LOCUS       DAKCAA010000001       107518 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000001 DAKCAA010000000
VERSION     DAKCAA010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 107518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.001"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            24..752
                     /locus_tag="OUE31_000001"
     CDS             24..752
                     /locus_tag="OUE31_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0221047.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(821..2344)
                     /locus_tag="OUE31_000002"
     CDS             complement(821..2344)
                     /locus_tag="OUE31_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCU0221048.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            2596..3777
                     /locus_tag="OUE31_000003"
     CDS             2596..3777
                     /locus_tag="OUE31_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCU0221049.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(3837..5465)
                     /gene="treC"
                     /locus_tag="OUE31_000004"
     CDS             complement(3837..5465)
                     /gene="treC"
                     /locus_tag="OUE31_000004"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HCU0221050.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(5916..8627)
                     /locus_tag="OUE31_000005"
     CDS             complement(5916..8627)
                     /locus_tag="OUE31_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0221051.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(8637..9338)
                     /locus_tag="OUE31_000006"
     CDS             complement(8637..9338)
                     /locus_tag="OUE31_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0221052.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            9524..10123
                     /locus_tag="OUE31_000007"
     CDS             9524..10123
                     /locus_tag="OUE31_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCU0221053.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            10204..11217
                     /locus_tag="OUE31_000008"
     CDS             10204..11217
                     /locus_tag="OUE31_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCU0221054.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            11325..12242
                     /gene="rbsK"
                     /locus_tag="OUE31_000009"
     CDS             11325..12242
                     /gene="rbsK"
                     /locus_tag="OUE31_000009"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCU0221055.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            12270..12665
                     /gene="rbsD"
                     /locus_tag="OUE31_000010"
     CDS             12270..12665
                     /gene="rbsD"
                     /locus_tag="OUE31_000010"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HCU0221056.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            12665..14038
                     /locus_tag="OUE31_000011"
     CDS             12665..14038
                     /locus_tag="OUE31_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCU0221057.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            14395..16539
                     /locus_tag="OUE31_000012"
     CDS             14395..16539
                     /locus_tag="OUE31_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCU0221058.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(16591..17631)
                     /locus_tag="OUE31_000013"
     CDS             complement(16591..17631)
                     /locus_tag="OUE31_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCU0221059.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(17908..19710)
                     /locus_tag="OUE31_000014"
     CDS             complement(17908..19710)
                     /locus_tag="OUE31_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0221060.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(19724..20476)
                     /locus_tag="OUE31_000015"
     CDS             complement(19724..20476)
                     /locus_tag="OUE31_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0221061.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(20485..20847)
                     /locus_tag="OUE31_000016"
     CDS             complement(20485..20847)
                     /locus_tag="OUE31_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCU0221062.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYIQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(21023..21895)
                     /locus_tag="OUE31_000017"
     CDS             complement(21023..21895)
                     /locus_tag="OUE31_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCU0221063.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(21946..22434)
                     /locus_tag="OUE31_000018"
     CDS             complement(21946..22434)
                     /locus_tag="OUE31_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HCU0221064.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(22572..23363)
                     /locus_tag="OUE31_000019"
     CDS             complement(22572..23363)
                     /locus_tag="OUE31_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HCU0221065.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(23418..24026)
                     /locus_tag="OUE31_000020"
     CDS             complement(23418..24026)
                     /locus_tag="OUE31_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HCU0221066.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(24019..24336)
                     /locus_tag="OUE31_000021"
     CDS             complement(24019..24336)
                     /locus_tag="OUE31_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCU0221067.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(24492..25220)
                     /locus_tag="OUE31_000022"
     CDS             complement(24492..25220)
                     /locus_tag="OUE31_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HCU0221068.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKSCGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            25379..26260
                     /locus_tag="OUE31_000023"
     CDS             25379..26260
                     /locus_tag="OUE31_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCU0221069.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(26497..27540)
                     /locus_tag="OUE31_000024"
     CDS             complement(26497..27540)
                     /locus_tag="OUE31_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCU0221070.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(27543..28211)
                     /locus_tag="OUE31_000025"
     CDS             complement(27543..28211)
                     /locus_tag="OUE31_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0221071.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            28353..30689
                     /locus_tag="OUE31_000026"
     CDS             28353..30689
                     /locus_tag="OUE31_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0221072.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(30804..31115)
                     /locus_tag="OUE31_000027"
     CDS             complement(30804..31115)
                     /locus_tag="OUE31_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221073.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            31296..32771
                     /locus_tag="OUE31_000028"
     CDS             31296..32771
                     /locus_tag="OUE31_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HCU0221074.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            32818..33402
                     /locus_tag="OUE31_000029"
     CDS             32818..33402
                     /locus_tag="OUE31_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HCU0221075.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            33404..33823
                     /locus_tag="OUE31_000030"
     CDS             33404..33823
                     /locus_tag="OUE31_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HCU0221076.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(34104..34388)
                     /locus_tag="OUE31_000031"
     CDS             complement(34104..34388)
                     /locus_tag="OUE31_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HCU0221077.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(34740..35450)
                     /locus_tag="OUE31_000032"
     CDS             complement(34740..35450)
                     /locus_tag="OUE31_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HCU0221078.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(35447..36919)
                     /locus_tag="OUE31_000033"
     CDS             complement(35447..36919)
                     /locus_tag="OUE31_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCU0221079.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            37057..37530
                     /locus_tag="OUE31_000034"
     CDS             37057..37530
                     /locus_tag="OUE31_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCU0221080.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(37683..38234)
                     /locus_tag="OUE31_000035"
     CDS             complement(37683..38234)
                     /locus_tag="OUE31_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCU0221081.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            38339..38869
                     /locus_tag="OUE31_000036"
     CDS             38339..38869
                     /locus_tag="OUE31_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HCU0221082.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(39352..39795)
                     /locus_tag="OUE31_000037"
     CDS             complement(39352..39795)
                     /locus_tag="OUE31_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0221083.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(39811..40971)
                     /locus_tag="OUE31_000038"
     CDS             complement(39811..40971)
                     /locus_tag="OUE31_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCU0221084.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            41478..43178
                     /locus_tag="OUE31_000039"
     CDS             41478..43178
                     /locus_tag="OUE31_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221085.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(43280..44113)
                     /locus_tag="OUE31_000040"
     CDS             complement(43280..44113)
                     /locus_tag="OUE31_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCU0221086.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(44417..46582)
                     /locus_tag="OUE31_000041"
     CDS             complement(44417..46582)
                     /locus_tag="OUE31_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCU0221087.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            46842..49136
                     /locus_tag="OUE31_000042"
     CDS             46842..49136
                     /locus_tag="OUE31_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCU0221088.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            49129..49794
                     /gene="pgmB"
                     /locus_tag="OUE31_000043"
     CDS             49129..49794
                     /gene="pgmB"
                     /locus_tag="OUE31_000043"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCU0221089.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            49787..50794
                     /locus_tag="OUE31_000044"
     CDS             49787..50794
                     /locus_tag="OUE31_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCU0221090.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            50816..51835
                     /locus_tag="OUE31_000045"
     CDS             50816..51835
                     /locus_tag="OUE31_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0221091.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(52116..53483)
                     /gene="nhaC"
                     /locus_tag="OUE31_000046"
     CDS             complement(52116..53483)
                     /gene="nhaC"
                     /locus_tag="OUE31_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCU0221092.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(53592..55013)
                     /locus_tag="OUE31_000047"
     CDS             complement(53592..55013)
                     /locus_tag="OUE31_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0221093.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(55256..57133)
                     /gene="tdc"
                     /locus_tag="OUE31_000048"
     CDS             complement(55256..57133)
                     /gene="tdc"
                     /locus_tag="OUE31_000048"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCU0221094.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(57424..58680)
                     /locus_tag="OUE31_000049"
     CDS             complement(57424..58680)
                     /locus_tag="OUE31_000049"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HCU0221095.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(58797..59002)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            59265..60566
                     /locus_tag="OUE31_000050"
     CDS             59265..60566
                     /locus_tag="OUE31_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCU0221096.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(60635..61234)
                     /locus_tag="OUE31_000051"
     CDS             complement(60635..61234)
                     /locus_tag="OUE31_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCU0221097.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            61488..62369
                     /locus_tag="OUE31_000052"
     CDS             61488..62369
                     /locus_tag="OUE31_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0221098.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            62382..63992
                     /locus_tag="OUE31_000053"
     CDS             62382..63992
                     /locus_tag="OUE31_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCU0221099.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(64069..64728)
                     /locus_tag="OUE31_000054"
     CDS             complement(64069..64728)
                     /locus_tag="OUE31_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCU0221100.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(65011..65676)
                     /locus_tag="OUE31_000055"
     CDS             complement(65011..65676)
                     /locus_tag="OUE31_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HCU0221101.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(65823..66428)
                     /gene="dhaL"
                     /locus_tag="OUE31_000056"
     CDS             complement(65823..66428)
                     /gene="dhaL"
                     /locus_tag="OUE31_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HCU0221102.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(66456..67466)
                     /gene="dhaK"
                     /locus_tag="OUE31_000057"
     CDS             complement(66456..67466)
                     /gene="dhaK"
                     /locus_tag="OUE31_000057"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HCU0221103.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(67441..67887)
                     /gene="dhaM"
                     /locus_tag="OUE31_000058"
     CDS             complement(67441..67887)
                     /gene="dhaM"
                     /locus_tag="OUE31_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HCU0221104.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            67990..68310
                     /locus_tag="OUE31_000059"
     CDS             67990..68310
                     /locus_tag="OUE31_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HCU0221105.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(68422..69291)
                     /locus_tag="OUE31_000060"
     CDS             complement(68422..69291)
                     /locus_tag="OUE31_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCU0221106.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(69387..70691)
                     /locus_tag="OUE31_000061"
     CDS             complement(69387..70691)
                     /locus_tag="OUE31_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCU0221107.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVSFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(70688..71197)
                     /locus_tag="OUE31_000062"
     CDS             complement(70688..71197)
                     /locus_tag="OUE31_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221108.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(71372..73507)
                     /locus_tag="OUE31_000063"
     CDS             complement(71372..73507)
                     /locus_tag="OUE31_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCU0221109.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(73590..75245)
                     /locus_tag="OUE31_000064"
     CDS             complement(73590..75245)
                     /locus_tag="OUE31_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCU0221110.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(75247..75561)
                     /locus_tag="OUE31_000065"
     CDS             complement(75247..75561)
                     /locus_tag="OUE31_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCU0221111.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            75731..75991
                     /locus_tag="OUE31_000066"
     CDS             75731..75991
                     /locus_tag="OUE31_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HCU0221112.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            76005..76319
                     /locus_tag="OUE31_000067"
     CDS             76005..76319
                     /locus_tag="OUE31_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HCU0221113.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(77049..77603)
                     /locus_tag="OUE31_000068"
     CDS             complement(77049..77603)
                     /locus_tag="OUE31_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HCU0221114.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(77729..79658)
                     /locus_tag="OUE31_000069"
                     /pseudo
     CDS             complement(77729..79658)
                     /locus_tag="OUE31_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(79964..80680)
                     /locus_tag="OUE31_000070"
     CDS             complement(79964..80680)
                     /locus_tag="OUE31_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCU0221115.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(80681..82504)
                     /gene="glpO"
                     /locus_tag="OUE31_000071"
     CDS             complement(80681..82504)
                     /gene="glpO"
                     /locus_tag="OUE31_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HCU0221116.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(82518..84014)
                     /gene="glpK"
                     /locus_tag="OUE31_000072"
     CDS             complement(82518..84014)
                     /gene="glpK"
                     /locus_tag="OUE31_000072"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HCU0221117.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(84150..85610)
                     /locus_tag="OUE31_000073"
     CDS             complement(84150..85610)
                     /locus_tag="OUE31_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0221118.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(85600..86895)
                     /locus_tag="OUE31_000074"
     CDS             complement(85600..86895)
                     /locus_tag="OUE31_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCU0221119.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(87227..87904)
                     /locus_tag="OUE31_000075"
     CDS             complement(87227..87904)
                     /locus_tag="OUE31_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HCU0221120.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(87934..89025)
                     /locus_tag="OUE31_000076"
     CDS             complement(87934..89025)
                     /locus_tag="OUE31_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HCU0221121.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(89126..89560)
                     /locus_tag="OUE31_000077"
     CDS             complement(89126..89560)
                     /locus_tag="OUE31_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCU0221122.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(90144..91601)
                     /gene="ascB"
                     /locus_tag="OUE31_000078"
     CDS             complement(90144..91601)
                     /gene="ascB"
                     /locus_tag="OUE31_000078"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCU0221123.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(91598..93493)
                     /locus_tag="OUE31_000079"
     CDS             complement(91598..93493)
                     /locus_tag="OUE31_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCU0221124.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(93551..95326)
                     /locus_tag="OUE31_000080"
     CDS             complement(93551..95326)
                     /locus_tag="OUE31_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCU0221125.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(95376..96872)
                     /locus_tag="OUE31_000081"
     CDS             complement(95376..96872)
                     /locus_tag="OUE31_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCU0221126.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLYYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(97066..98688)
                     /locus_tag="OUE31_000082"
     CDS             complement(97066..98688)
                     /locus_tag="OUE31_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCU0221127.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(99016..100329)
                     /locus_tag="OUE31_000083"
     CDS             complement(99016..100329)
                     /locus_tag="OUE31_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCU0221128.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(100574..100798)
                     /locus_tag="OUE31_000084"
     CDS             complement(100574..100798)
                     /locus_tag="OUE31_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221129.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(100818..101240)
                     /locus_tag="OUE31_000085"
     CDS             complement(100818..101240)
                     /locus_tag="OUE31_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HCU0221130.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(101382..102092)
                     /locus_tag="OUE31_000086"
     CDS             complement(101382..102092)
                     /locus_tag="OUE31_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221131.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(102110..102607)
                     /locus_tag="OUE31_000087"
     CDS             complement(102110..102607)
                     /locus_tag="OUE31_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0221132.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(102644..103096)
                     /locus_tag="OUE31_000088"
     CDS             complement(102644..103096)
                     /locus_tag="OUE31_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCU0221133.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(103231..103836)
                     /locus_tag="OUE31_000089"
     CDS             complement(103231..103836)
                     /locus_tag="OUE31_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCU0221134.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(104286..104906)
                     /locus_tag="OUE31_000090"
     CDS             complement(104286..104906)
                     /locus_tag="OUE31_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HCU0221135.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(104908..105777)
                     /locus_tag="OUE31_000091"
     CDS             complement(104908..105777)
                     /locus_tag="OUE31_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HCU0221136.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(105800..106207)
                     /locus_tag="OUE31_000092"
     CDS             complement(105800..106207)
                     /locus_tag="OUE31_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCU0221137.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(106226..107515)
                     /locus_tag="OUE31_000093"
     CDS             complement(106226..107515)
                     /locus_tag="OUE31_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCU0221138.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        31547 a        22373 c        18879 g        34719 t
ORIGIN      
        1 aaataaaata aaggagtaat gatatgattc ccatttatat ttgtgaagac gatccaaaac
       61 aattagaagt tttatcaacg gtgatcaaaa atagaatcat gattgaaaac ttagacagtt
      121 atgtccatat ttctacctct gatccggaag aacttctcaa tgcagccaag atcagaactt
      181 cttcttttgg tatttacttt ttagatatcg aactagaaga cagtgaaatg gatggtgtag
      241 cgatcggtaa attgatccgt gaattagatc ctttaggaaa aataatctat gtgacttccc
      301 atacggaaat gtcgatgaaa atcttaaaaa gcaacatcga accgactgat tatatcgtca
      361 aagaagatct ttatgattta aaagaaaatg tcgagcatat cctgagcaaa attttcgaag
      421 attttcaaat gtcccaaatc caaaaagata tcttcaaaat agagtttaat gatgagatca
      481 aatttttacc gatcaaagac atccaatatt tttctacttc gctaggagcg ccacataaac
      541 tggaagtcca tttgactcat gcccaattac aattctatga gaagatcaaa gaaatcgaga
      601 aaatgcatcg gaattttatc cgttgtcata aatcctatgt tatcaataca caaaatgtgc
      661 ggtcgattaa taaaaaaacc agagaagtca cgttggcaaa cggcgagacc atcccagcct
      721 ctatccgtgg attaaagaaa ttgatttcat aaaaagaacc gaatagtttg gaccgactaa
      781 atgaccagcc gatccaaacc cttcggttct tttttgccta tcagtgcaaa agcatttcct
      841 gtgcaatttc acgtccatcc attgtatctg gataaaatgt tggccaattc tccatttctt
      901 tcagcaatac ttcttgactt tcatttcctg catataaatg aaaatgttcg gagtcagccg
      961 gtgcaatcgt gtgatcactg aattgaatat atctaaaagc gccactttcc ttatcttctg
     1021 cttcgaatag ataccttacg ccacggtttc ctgcctcgta ggtcaagatt tctttcccta
     1081 cataacgata atttgaacgt ttcgttgttc cattcttaaa cgtaaatgcc atctctttct
     1141 cactgatctt gattgaagca atatctgttt gatagccctt cgtataatat tctttatatt
     1201 cttgtgctgt cttatcctga ttcaattttt ctttatattc aaaaacagga tcaaaagtcc
     1261 catcttctac atacgtatct actgtttgcc aagttcctgc ccaatctgaa agagagcgat
     1321 cttgtacatc ctcgtcttca aaataaccgt tgtagacgct cttttctttt ttgggggtca
     1381 aagtatcttc tagcgggttt tctgtctctg tcgttttttt caacgcttcg aggtttgctt
     1441 ccatgataga aagatagttt tctccatttt ctatttgttc attcgtcaat ccttccaaag
     1501 gattcaatac ttctaaagat acacctgctt cgtttgctaa cgttctggca atactatctt
     1561 tggcgttttc ttcaaaataa atatagttga ttccatgttc tttaacaaag tgtttcagtt
     1621 cagcaattct cgccgcagac ggttcttcac tagaagaaag accagcaatc gatacttgat
     1681 tcaatccata ttctaacgct agatagttga atgcagcatg ttgcgtgaca aaagatcttt
     1741 gttttgcttg cttaaaggtt tcttgataaa gctgatggag tgcttgaagt ttctcggtat
     1801 aggctgctgc attttttgtc catacttcct gtttttctgg gtaagcttca atcagctgat
     1861 cacgtatgtt tgctacctgc ttgattgcta aacttggagc tagccataca tgtgggtcta
     1921 gctcatgtgt atggccttct tccccgtgtt catggtcatg atcatgtcct tcttcacttc
     1981 ccggaagtaa aagcatacct tctgtcgctt ttatcgtatg gacattgcct tcttgtaatg
     2041 ttttttggat tgcggggacc catgtttcca tgttttcatc attataaaca aagatatctg
     2101 tatcttggat ctttgccatg tctttagcag aaggttcata atcgtgggaa tcagtccctg
     2161 ctggaatcaa taactctact tctccttcat ccccgacgat tgcttttgta aaatcataca
     2221 tgggataaaa ggtcgtcatc acgctcaatt tttctttact gtcctcggct ttcccacttg
     2281 ccccgcaagc agttaacata cctgctaaaa ccagcatggc caatatacct atcaatcgtt
     2341 tcatttatga cactcctctt ctcatcttct ttcatttgaa tgttccgatt cgcttttcgc
     2401 aaaccgtaat agttacgttt tagcaacagg atttaattta tcatatggtt aaaagaactg
     2461 tcaagcgttt tcttatttta attgatgaga aagtttatat gaatgattga cgatattttt
     2521 gcaatcaacc tctatcattt tccttttata cccgcttttg tctataatga agttatagat
     2581 aaaggaggaa aaagagtgaa aaaagaaaca gatacaacga atcgtttgat ccgcttttta
     2641 ggaggaaaaa cctcttacta tgttttagga atagttatct tacttgcgct gatcatttat
     2701 tttttccatc agatctcgtt tatattcaag cctgtcggaa tcattatcgc tactatcttg
     2761 cccccattat tgtttgcact gatcttgtat tatcttttgg aaccagtcat caaacgtttg
     2821 agcaagcacc tttcgaggaa cttgtcagtc attatcgttt atgtgattat tttattttta
     2881 ttggggcttg gaagcatatg gcttattcct tttcttgaag aacaggcaaa gacattgatc
     2941 agtagtttgc cagatttgtt tcaagatttt caagagagtc tccgacaatt tttggagaaa
     3001 acaccttttg ccgattcatt taatcaattt ttcgcttcta ttgacgacgt gacgtctgat
     3061 atagctggat ttattggaaa ttattgggaa agtggcgcac aacggatcag caacattttt
     3121 tcaactgtta cagctatttt tattacttta tttactggtc caattgtcgc ttttttcctt
     3181 ttgagagatc ctcaaaaatt ttatcagtca gttttagcga ttgtcccacc agcatttcgt
     3241 acagatttta aaaatttgac aaagattgct aatcaacaat tgggttcatt tctaaagggg
     3301 caaatcattg cttcatttat ccttggagca gtctactggg tttgtttctt actgatcgga
     3361 ttagaatttg ctagtgtttt agctatttct gctgggttgt tatgtatcat tccatatatt
     3421 gggccgttta tcgccttctt tccaggtttg atcattgcat tccaagactc tacttttatg
     3481 gctgtcaaat ttgtcattgt ctggtttgcc gtacaacttc tccacggtga cttggtgatt
     3541 cctcgagtaa tgggtgatcg tttacagatc catccgatta cgatcttaat cgttttactt
     3601 gtcatgggtg atctaatggg aattgtgggc gttatttttg gtattcctat ctatacgtta
     3661 gtcaaattac tcgttacttt tattttccgt aaattcaaac aacgctacaa taaattttat
     3721 ggcgataaag gagagtatga aaactcttca ttttctgaag aagattattt taaataaaac
     3781 acaaaacgtc gatcttacga gaatagctcg taggaacgac gttttgtgtt tttgttttaa
     3841 tttttcagca aagcaattgc ctggtatggt tttagctcca gactttgatg aagaacagta
     3901 tcggaataat tatcgataag aatattggct tctgtgaatc cttctgggat ggcgatcctt
     3961 gtatctttat catagaaatt tgttaataca agcagctgct gtccttcaaa ttggcgaaga
     4021 aagccataaa cttccggatg atttgcttca taagcatgat aatctccttg tgcaacgatt
     4081 ggatatgttt ttctcagccg aatcaatttc ttgtaatagg acaaaataga atcttcagaa
     4141 gatagttctt tttctacatt aatctcttct agcttgcctc caacttttaa ccaaggtttc
     4201 cctgtagtaa atcctgcttg ttctgtgtct gaccattgca tgggtgttcg agagttatcg
     4261 cgagattttg ctttgatccg acgaaacgct tctttttctg tgaatccttg ttcaaggagt
     4321 aacttataag cattcaaact ttctacgtca atatagtcgg aaatcgatga atagtctggg
     4381 tcgatcatgc cgatttcttc tcccatataa atatagggcg tcccacggtt caaatggatc
     4441 atggttgcta gcatctctgc tccttgtttt cgatactgat cgatagctac aaatcgattg
     4501 agcgcacgtg gctgatcatg attattaaaa aatagagcat tccagccgtt accctcactc
     4561 atcttttctc cccatgtatg aaatagtcgc tttaattctg caaaatcaaa tggaggagta
     4621 gaccatttat tcccattttc ataatcgact ttcaaatgat ggaaattaaa gaccattgat
     4681 aattcttctc tactaggttc tgtatacaag atacaatttt cgatcgtcgt agagctcatt
     4741 tcaccgactg tgatgatagt ggaatccgtc ccaaacgttg cttggttcaa ttcttttaga
     4801 tacgtatggg tgattggttt gtccgtatat tcaggtttgc catcattttc tttattattt
     4861 ttcaattgtt cgtctttacc gataacattg ataacatcga aacggaatcc ttttacccct
     4921 ttttccatcc aaaaacgaac aactttgaat agttcctctc ttactgcttg gttccgccag
     4981 ttcaagtcag cttgtgtccg atcatataag tgcaaataat atttccccgt atctccaaat
     5041 ggcgaccaag cacttccacc aaattttgat acccaatccg ttggctcttc tcttaaaatg
     5101 aagaagtcct gataatgctg gtcccctgct agtgcttttt tgaaccattc atgttctgtc
     5161 gaaacgtgat tcagcaccat atcgagcatg atttctatcc ggtatttctt tgcttcggct
     5221 attagctgtt cgaattcctc catcgtacca aagataggat cgatggctgt gtaatcagag
     5281 atatcataac cgttgtcttt ttgagggctt ggataaatag ggtttagcca aatcatgtcg
     5341 atgcctagat cattcagata cgggagtttt tctttgattc cttttaaatc tccaattcca
     5401 tcaccattac tgtctttgta agatttggga tagatttggt aaatgacttt gtctttaaat
     5461 gtcatggata tttacctcca ttcaactgat ttattaccta ccacaactta tatatacaag
     5521 ttatcattta ttattataac tgaaccgaaa gcgtttgtaa aatttatctt tatacattct
     5581 aagaggtctg ttgcccaata aaaaacaaga gatcagacat gtatttgtct atcctcttgt
     5641 ttaaaatagc aaaatattct tgtttcttct ataaatggtg ttcaaaagct tttatctacg
     5701 gcaatcagtc ttctcaaatg taaaacatga ggagctaatt ttatttgagt attctttttg
     5761 ctcgatgcag gacggctttt ttacaacctc tgattcatgg tgttcaatca gctgtccttc
     5821 ggtattagct caaaaaacgg caaaatatga aaaactattt tgccgtttgt ttctctaata
     5881 ctcaggtcaa accgctgatt tcacaacctc tgtttttatt cattcgattt caacgcatca
     5941 atcatatcga tatgctttaa tttgaaatgg gtaacaatca tcacaataac cgtaaatacg
     6001 atagttaatc ctgctgataa gacataagcc caccatgtga tcactaatgg aaagatgaca
     6061 ttctccatag acgcttgttg caagatgaag tcagtcaata tatatcctac accaaatcct
     6121 ccgatgattc ctaaaagagt aaagatgata ttttctcgaa caatgtacat cgtgacttct
     6181 ttatcaaaaa atccaaggac ttttattgta gataattcgc gtacacgctc ggaaatattg
     6241 atattagtta gattatacaa gacgataaaa gccagcagtc ctgataatac gacaaagatt
     6301 aagacaaccg agtctaagtt cgccattgat tcttcttgcg tttcgatttg tttggacatg
     6361 aaagacgtat ttgtcacagc gtctgtggca agcagtttct cggaaagcat ttcttcttct
     6421 tttgttgtca tcttatctgt acgcagcaaa aatgcattat ccatcatcga ttgatcagta
     6481 actgaagcat aatattcagg ggacatataa ataaagctac ctagatagtt tttcacgatt
     6541 tcttttactt cgactttcca ttctttttga tcttcatcat aaagcgaaat atgatctcct
     6601 gtagataagt caaatagttc tgctactttt tgcgtaatag cgattcctgt tttaggcaag
     6661 gagcgtgggt tctcttcaag atcagttaaa tggataaaac gatccaaatc agctgtttta
     6721 cttggtacga tcactgtcag actttgcgaa gcatgtcctt tttttctcaa ttctacggtt
     6781 tgagtatgaa tagctaggat ctcatttact ttttcttgct tctgcagcat atccgctgct
     6841 ttttgacgac tatcttccgt ggatgaatcc aatgtaacga ttgcttgata gtcaatgatc
     6901 ggtccaaatt gtttggctga aacagaactt agagaatctt tcaatcccac gcctgcaacc
     6961 atcagcccgg cacatccagc aattccgata atcgccataa gcattcttga cttatatcgg
     7021 aagagatttc ggtaactgat tttttgatta aagctaaggc gtgaccacag cggagtgatg
     7081 tattcaagaa aaatgcgttt ccctggcttc ggtgctttcg gttgaagcaa tgcagcaggc
     7141 cgttctctta aatctttgaa taaaacgatc attgcagcgc caaatgcggc aatgaagaat
     7201 gcggcagctg cttgtaaaat cggcggccag tcataaaaaa taagcgcact cccaatatca
     7261 taccgctcgt tagacagctc aaaaatgatc cttggcaaaa gattcgttcc taatatcgtt
     7321 cctaaaacaa tacctatccc tgaggctaga cttgcataga ttgcatattt ttttgcgatt
     7381 tcaactttcg tataacctaa cgcctttaat gtcccgattt ccctgcggtt ttcttctacc
     7441 atacgtgtca ttgtcgtaaa ggtgatcaat gcggcaataa agaaaaagaa aacaggaaaa
     7501 acattggcaa tcgcagcgat acgatcagac agatcaccaa attcttgaaa accgacattt
     7561 tctgaacgtt cattgtatag gtatgatggt ttagttaaat tttcaatttt ttctgcattt
     7621 cgattcaatt cttcctctgc agaggccagt tcacgttctt tctcaactaa ttgcctttct
     7681 tgttcagcaa gttgagcttc ttgttgagat aatgtttgaa cagcgattgt tcgttgcgct
     7741 tcaggaagct gctggatagt tgctgactgt tgcgctaact gttttttagc atcttctaac
     7801 cgtgttcttg cttgcgttgt ttgtgctttg ccatccgcta ttttttgctg tgccggttct
     7861 aattcttcgt tggccgattt tttcagctct tctaagcgtt cttcgggtcg atcttgtaaa
     7921 tacttttctg ccttttcttg attttgctcc attttatctt tgtaagcttt gctgtacgta
     7981 ttcaaattct ttacgtttgt aaaatcaaga tataagacag aataaatatc tgttttaaaa
     8041 acggattcag gtaaatagac aaaataatcg acgctaccat ttccgacgtt cgcgtatcct
     8101 ctctccaaat tgttgatgaa caatggagaa cggacaaagc ccgtgatggt atactctttt
     8161 tctttcaatt catctgaatc aatctgataa atatcaccga ttttataccc ttcatcttcc
     8221 gctttttcat ccaatacaag ctggtttggt ttttccggga gttttccatc agttaattgt
     8281 agcttgttct gcttgttatt tttgttataa gaaaatattt gaatcacttc gtttttgcca
     8341 gtattggaat aatagatctg ttttcctgtt tctacttttg catctgggat cttttctgct
     8401 tgagcaatat ctttttgtgt caagccacca gtagaaacga tttgcaaatc agaaagtcct
     8461 gctgtaccaa catagtgatc catcgttttt tgcatgacag gtccagcagt tttgacacct
     8521 acaaataaaa gtgttcctag catgacaata aggatgattg caatgaatcg tcctttagat
     8581 tgccgaattt cgcgaaaacc tgctttaaga tatgttcttg ttttcataaa atccccctac
     8641 catacaatct catcaatgga tgaaggatga tcatttaatt caacagacct tactttagca
     8701 tcattaatgt gaatgactct atcagcgatg ggcgctaaag cagaattatg tgtaatgatc
     8761 aaaacggtat tgccgtgttg tctgctagcg ttttgcaata atttcaatac ttgcttgccc
     8821 gtttcaaaat ccagcgcgcc tgtcggttca tcacataaaa gaagtttggg atttttagct
     8881 agtgcacgag caattgaaac cctctgctgt tcgcctcctg ataattggga cggaaagtta
     8941 ttcaatcgat gagctaggcc cacttgcctc aatacctcta caggatcaag cgcatcagga
     9001 gaaacttccg ttgccaattc cacattttct tttgctgtta gattaggaac gagattgtag
     9061 aattggaaaa cgaaccctac atctgttcgt cggtaagcag taagctgttt atctgaaaat
     9121 tgcgcaatat ctgtgtcatc aataatgatc tgaccttcat caggtgtatc catcccacct
     9181 aaaatattaa gaatcgttga ctttcctgct ccacttggac caagtataat cactaattcg
     9241 cctttttcaa ttgaaaaaga aatatcgtca tttgctgtaa tggtcgtttc tcccattttg
     9301 tatcgtttgt attcattttt tacttcgaca tacttcactc tgattcctcc attttcacga
     9361 tatttctcgc tatatctatg catcgaatgc gttttctcac acttatttat tttaccactg
     9421 aatttctcta gactaaagaa aggaatcctt taatttagtt gacaaataaa cgatttatga
     9481 tttacttaca taaaaaacat tgttatttga aagaaggaac atcatgaatg atttaaagga
     9541 aaatatgatt tttgatttat caaaaactgc ttttgtcgcg atcgacatgc aaaaagagat
     9601 cgtaaataac ggtacactct ctccacacac tgcagcatct attctgacaa acaatgattt
     9661 gttagtaaga acattgaaac gtaccgctgc cttgaaagtt ttagtgaacg tagacatctc
     9721 cactttccct tatttgagtc aacaaactga tatgggtgga atgactgctt ctgtacctcc
     9781 agaattcact gatttacttt tgaaggattc tttgaaagat acagataata tgttgactat
     9841 cacaaaatac aatccaagtg ctttttttgg tacttctctt gatcttcaac ttcgccggcg
     9901 tggaatcgaa actatcattt taagcggtgt agcgacaaca aacggtgtat atgctactgc
     9961 attagatgcc tttcaacacg ggtaccatat cgtgcttgct gaagatgctt gcagtgatcg
    10021 tgacaaagaa tcccatcaat tgttcataaa aaagatattt ccgaaaactg cacgagtacg
    10081 ctcaacgaaa caaataatcg aagctatcca acaaagcaaa taagtactgg cacacgtgat
    10141 tttcatttac ttctttttga tttcatggga aaataaccac aggatttaga taggagtatg
    10201 aacatggtga aaaaaaagat cacaatcaaa gaagtcgcta aactttccgg cgtttcaatc
    10261 acaactgtct ccttgatatt aaatggaaat acggagaaat tcagtccgaa aactgttcag
    10321 aaagttttag ctgccaaaga agaattaggc tatcagcctg actattttgc tagacaaatg
    10381 attaccaagg aaacgaaaac aattggtgta ctcgttcctg atatcacgaa tccattcttc
    10441 agtacactga tgcgaggaat tgaggatatc ttgtataagc agaatttcgt cacgatatta
    10501 tgtaatgctg attctgatca tcaaaaagaa atcgaatatc tagccgagct cacacgtcga
    10561 ggtgtggatg gattcattat cgcgacttct gctgtctcta cagatgcaat caacgaaaat
    10621 ttgaaaaaac aaggccggcc cttcattgtt ttggatcaga aaaaatctga aggatttagt
    10681 gatgccgtac gaacagacga ttttcgcggt ggttacctag cgggcatgca cttgcttagt
    10741 ctaggacatc aaacgatcgc ccttgtctat cctgaaaatc caccggaaaa tgtccacgct
    10801 cggattgagg ggtttaaatc tgctcttgat gtttaccaaa tccctcacga ccaactgatc
    10861 ctcttaccta cacagttctc aaaacaaggt ggctaccaga tcacagcaga acttcttgat
    10921 tctgctgcaa ctggtgtgtt tgctttaaat gatgaattag cttttggatt atatcgcgga
    10981 ttagaggaag ctggaaaaag catccctgaa gactacagca ttattggcta tgataatata
    11041 gatatgtgcg agtatatcaa gccgaaactg acaacgatcg cacaaccaat cttcgaattg
    11101 ggacaaacat ctgccaagtt attgttagat cggatccaat tcccagaaaa agaatgggaa
    11161 gaaaaaagat tacctgtacg attagaaaaa agattttcaa ctgcaccctt gaaatagctt
    11221 tcaaggtgtg ctatattttt atcgaactat taaaacgttt tactaaaacg ttttaaaaaa
    11281 taattttccc atcaaaataa atgagatagt tggaggtttg taaaatgaac acggttacag
    11341 taattggaag tattaatatg gacactaccc ttcgtttaac caacatgccc aagccaggcg
    11401 aaacgatgca tgcgcatgag atttttcacg ctggcggagg taaaggtgcc aaccaagcag
    11461 tggcagccaa acgttcaggc gcacggacat cttttattgg aggcgttggg gctgacagcg
    11521 aaggacaaca gttattagat ctactgacaa aagaaaacat cgatacatct gggatagctg
    11581 aaatccaagg cgccacaacc ggacaagcaa tgattatggt agacgcagca ggagaaaata
    11641 gtatcttgat ccatgcaggg gcaaataatg ctttccatga acaagaagtc ctaaaaaaca
    11701 agcaactgat tacaaacagt gactttatta ttgctcagtt tgaaagtagc ttagatgcga
    11761 cgatcctagc tttttctatt gcaaaagacg caggaaaaac aacgatcctg aatcctgcac
    11821 cagctcgtga aacgattcct actgaactac ttgaaaagac agatatcatt ataccaaatg
    11881 aaacagaaac agaaatcatt acaggaatca gagtgacaga tcataacagt ttggtcgcag
    11941 cagccgaaaa actccatgaa ttaggtattg gaacagtaat cattacacta ggcagtgccg
    12001 gcgctttcta tcatacagaa aaagaacacg gtatcgtccc tgcttttaaa gtggatgccg
    12061 ttgacacaac agccgcaggt gatacattta ttggcgcatt aagcagcaca cttcagccag
    12121 accttagtaa cttgaaagaa gcgatccttt atggaaatct agcctcttct gttgctgtgc
    12181 agtcttatgg tgcgcaacct tctatccctt accgcgaagc tttagaacaa tcagcagtct
    12241 aaaattaaca atgagaggaa gaaacaaaca tgaaaaaagg aaaagtaatc aattcagata
    12301 tttcacgagt aatcgcacaa atggggcact ttgataaatt aagtatcggg gatgcaggca
    12361 tgcctgtccc ctttggtact gaaaaaatag atttggctgt ctcaaacggt cttccaagtt
    12421 ttttatctgt tttagaaaac gttttagaag aacttgaggt acaatcgatt gaattggcgg
    12481 aagaaataaa gacaatgaac ccggaaatat tggaaaaaat caaattattg ttaccagata
    12541 caccgattag ctttatccca catgaagaaa tgaaaaaaga gttgaataac tgtcatgcat
    12601 ttattcgtac aggcgaaatg acaccttacg ccaatattat attagtgagt ggagtggtct
    12661 tctaatggaa acgacaatga atcctgaaca gatggtactg tccgagcaga ttcatatgct
    12721 gattgaacag ttgggaggaa aagacaatat tgattctgtc cttccatgtg cgactcggct
    12781 tcgtatcaaa ttgaaaaaac agccagtagc caatgcagaa aaattaaaac agcaaatccc
    12841 ttccattaag tatttcattt tactcgatag atatgcagaa ataatcatgg atcagggatt
    12901 ggctcctgct tacaaggaat tgacgcgtca aatcgatcat tcagctccga aagaaaagct
    12961 aaatccgatc gaaaaactat ttggtttgat atcggaaatc tttacgccga tcattccgct
    13021 gtttgccggt tctggtatat taaaaggtct ggttgtttta gcgactacga ttggctggct
    13081 tagtgaaaca agcggaactt atcatatttt gtctgctgcg tcgaatgccg tcttttattt
    13141 tctgccaatc tttcttgctt tttctgctgc caaaacgttt aaagtgaatg gatatattgc
    13201 ggctgtcatt gctgcagcac tgattgaacc gaatctgacc tctttacttt cagacagtgg
    13261 caaagcagct actgattttc tggggattcc tgtagtactg atgcagtata cgtctactgt
    13321 catgccggcg attttaggta ttttctttta ttcttttgtt gaaaaattcc tcaaaaaata
    13381 tattcgcgaa aatatgcaat tagtatttgt acctttactt tcattagtta tcacggttcc
    13441 tttgacgtta atggtattcg ggcctgcggg tgtttacctt ggcgaaggtt tagctgccgc
    13501 aattacttgg atgatggata ttaacggacc gatcagtggc gcaatcatcg ctggtggttg
    13561 gaatattttg gtaatatttg gtatccaatg ggctgtaaac cctgtcatga tcagtaatat
    13621 ctctgcttat gggttcgacc gaatcgttcc gttgacagga gcagccaatt ttggaatggc
    13681 tggtgcagct ttaggtgtat ttctgcgaag taaacgttca aaaacccgtt cgatctccgg
    13741 ttctgctttt gcttcgattt tacttgcggg agtgaccgaa ccaactgttt acggaattgc
    13801 gatcccattg aaaaaaccat ttgttgctgc ttgcattggt gcagctgctg gtggagctgt
    13861 aatgggattt gcccaagtga aagcgatcgc ttttgtattt ggtagtctga ccacattgcc
    13921 tgcattcatt tccggtactt ttttctggta cttagcagga ctggctgtta gtctagtcgt
    13981 agcaatgatc actactctcg ttagcgggtt tgatgaagac ctaatgtctt atgaatagtt
    14041 aatgaaaaag actgaagtat gagatgttta tcacatattt cagtcttttt ctttttagga
    14101 tcattatttt tataaatttt tgtgatactt tccaaacttt ggtataattt acatatgcat
    14161 aaccattttt atccccactt gtttatcccc aaacaaaggt ggtctatgca ataaaatgaa
    14221 cgtcaaagaa aaacgaatga atgctcgttg cttatttaca aattgtttta tttagaatac
    14281 acagacagat ttatgaaaag aaaaagcttt tcgacacgat tatctgttcc aaaaaatgtc
    14341 taatgaatgc tgaataagac agaaaatcaa tgaaaggaaa aggactagtt tattatgaaa
    14401 aataaaaaaa cgatacgttt gctagctgct acttggctga ttgctccgtc tgttttgtcg
    14461 accaataccg tatttgccgt agataatcaa atagctgatc aaacagtcac aacagatacg
    14521 actacatcca gctcagctac tagtgaaaca acggattctt ttacagaaga cccaactgga
    14581 acaactaact caacaacagg atcgaccgag ccaactgaaa ttgatccggc tgatccatca
    14641 gaaaatgaaa agccagccga gacatattcc cttacaattg ctccttcttt gattggtaag
    14701 atccaactga ctgcttcgac agcggattcc cctgaacagc aacctttgga tattacggaa
    14761 agtggaacgg tagaaggttt attagcggaa acgaaggtaa cttacactat tacgccagct
    14821 gaaggtgaac aaattgcttc agtcgctgtt aatggtgcca aagaagtaaa ttatgatgca
    14881 aagaccttta cagtaggtac gaacaattta tctattactg cagaatttaa agctggaccg
    14941 gatacttcaa cagagaaacc aactgatcct agtgaagaag tccctagtac accagatccg
    15001 gaaacgccaa acaaaccaga tgtgggtaat aacaacaata ataatggttc aaataattca
    15061 aacaataata acaataattc gaacagcggg aattcttcga atcaaacaaa cccatctgga
    15121 tcgaataaca atggaaatac tcagagagaa ccaaaccatc caaacaatgg ttcatcgaat
    15181 ggcggaacga acaatgcttc atctcgtcca aatacagcaa atcaaagcgg tatagagaat
    15241 ccatcttctg cttcttctga ttttgttgta aaatcaccaa ttgatgctgt attgcctaca
    15301 aatacaacga atgtccaaca agcaatcgtt cgagaagcat tcaagcatct tggaaaacca
    15361 tatgtatggg gagcaaaagg tccaaatact tttgactgtt ctggtttgac ttattacgta
    15421 tatatgaaag caaccggtca ttatatcggt ggctggacag gcgaacagca atatgcaggt
    15481 acgcagattc cagtaagtca ggcccaacct ggcgacctcg tcttctgggg accttcttcc
    15541 ggtgttactc accatgtagg tatctatatt gggaacggac aatttatcca tgcgcctcaa
    15601 ccaggagata aagttcgagt aacttctatt tcagatttca cgcctgattt tgctgtccga
    15661 gtaaacttag caggtttacc tgctgcttca ggttcgctga caggcggctc atctatttta
    15721 gatggattag atggctcgtt ccatttcagt caaaaccaaa caactgatca gttcttgaaa
    15781 aagattgcag atgatgcaca ggaaatcggg caaaaagaag gaatctacgc atcagtcatg
    15841 atggctcaag ctatccttga aagtggatct ggaaacagct tattatcaag cgaaccaaat
    15901 cataaccttt ttggtatcaa aggatcatat aaaggaagca gcgtgacctt caatacactt
    15961 gaacaagata gttccggaca aagctaccaa atccgcgcac aattccgtaa atatccttct
    16021 tacaaggaaa gtttggaaga ctatgccgac ttgatcaaaa atggactgac tggcaatcct
    16081 gatttctaca aaccaacttg gaagtcggaa acaaaagact acaaagaagc aaccaaatat
    16141 ttggaaggac gttatgctac agatcgccaa tattcacaaa aattgaacgc gatcatcgaa
    16201 gcgtacgacc tgacaaaata tgatgaaccg aaaaaagaag cagcaacaac tgaagaagca
    16261 aacgctgaaa tcctcaatat gtctaagcga ttcgatgtgc caatcaaatg gacaacagat
    16321 ggcgtgccaa tcacaggatt agaattttca acgataaaac gcgtcaacaa cgcttcttcc
    16381 atcttccgtg tcgcttcaat ctgggatttg tggaacaatt ttacggcaag acagatacca
    16441 gaaacaacta ctcgtacagt taaagctgca actgttcctg tactaacctt gttaagttta
    16501 gacaaatcat tctggcttga tctgccttta aagaaataga ataaattaaa aaggggatgt
    16561 gacactgtca cactcccttt ttaatttatt ctatttcttt atatttattt tgtattccgt
    16621 tacaaactcg cgtacttggt taggttccag agtgacatct ccaaaacttt caagtcgctc
    16681 cgctcctggc agttcttgag tctcaaatgt gataccgcca tgatttacta atttattccc
    16741 gcgcatttcc ggtccatctt ctccaaaatt tgctgtaaaa atcacgattc ctgaagcatc
    16801 tgtttttact tggatcgata ctttttcatc tgggcttgtc aattccgcag catttagtaa
    16861 accagattgt tttttcaaca aaaatggatg atcgatgccg cccactatca ttgattggcg
    16921 aaaatcactg gcaaagacct cacctaattt tttaggacgt tggaagtcaa atgctgtgcc
    16981 acttactgaa actacttctc ctgtaggcgt tgtatcttta ttgagcgtag caaataatcg
    17041 gctattcaac caaagtatat gttcgtcgat tgactgtgct ggatcaccgg ttaaattgaa
    17101 atagacatga tttgtaggat tgaatactgt tttgcggtca ctgatccctt ggaccgtcac
    17161 tcgccatgta tcatcgttcg tcagcgtata ccgtacttct acatctaaag ttccaggaaa
    17221 tccgttttcc atatctgggc tagtctgata gaaaatgacc gatgcttcgt tttcaccatt
    17281 gatgactgta taatgccact gcttggcttc aaagctaggt gcaccaccat gtaaacaatg
    17341 accagtgtcc gggtctgttt ttacttcgaa cgtttcatca tctaatttga atgtgccatt
    17401 cgtaatccgt ccagccatac gtccgattga agcaccgata taagggtctt tttctagata
    17461 ttcttttgct tcatcaaaac ctaagatcaa ctctcgtttt tcattatcga ttattgtttg
    17521 aaaatgaaca acccgtgccc caagatcact gacagacaaa gatgtcccat tttgattcgt
    17581 gatcgtaatc aagtgatagt tttcgccaaa attttgttca ttgatttcca tgttccttgc
    17641 accctctttt ctttcatttg cactgattcc agtatacatg gaaaccgttt tcttaacagc
    17701 ttattccgtg agtaacgaga aaaaatttac tatattctaa taaaagaccg tgaaaaaaag
    17761 gttgtgacaa aaatattgtc acaacctctt tttccgaaca aacggtgttc aaaagcttgc
    17821 atctgcggta ataagcccaa ccaaacgaaa aatatgagga gctatttttg cttggctgtt
    17881 cttattactt gatgcaggac agctttttca caatctcttt ttcaatacga ttccagtata
    17941 taaccatgtc gtcagtacat agtagatgaa atacaatacg aagaatatcg taaacggaac
    18001 ccaaatatct ttgtatggat tttgcatgaa tagaccaaac atttgtaatc cgaataagac
    18061 atggactaca cctaagattc ctggtgctaa gaataacacg cctacttctc tacggatcga
    18121 ttgtttaagc aacccgcgtc gtgttcctat cttttcaagc atttcataac gagcaatgtc
    18181 actcttgctt cctgacaaga tcttgaacat caaacagcta gcaagcatgg tcaagaaagc
    18241 taaacctagg aagaatccca taaattcaaa accagagaat agaccattat acacttcata
    18301 catttcatat ttctggttgc tgtactctac tttttgcaaa gatggattgt tcattttatt
    18361 ttgagcaaca agtgtttcga ttggtttcag gtttgcttgg aagtctttta cctgaactag
    18421 ctgtaaagtg gattgtggca agttcagttg atcaaattct gattgactga ctaccttgat
    18481 ttctttttct tgctgttccg gcaattcata gcttcgaagt tcctcttgta cagtcagttc
    18541 attcattttt ttagcaggaa ctttttcttt cgtgatcttc ggcggtgttc catcttcatg
    18601 ttttatcatg atcaatggtt gagccgcaaa ttcacttgca ttatagtaaa tcgttcccgc
    18661 atcttctttt tgagtataag aagcagaaag tgttggtgaa agttctttga ttttttgctg
    18721 atcttctgcc cgaggattat tcatcactag atcatatcca gaattgtttt ctgtcaagtc
    18781 tgcaatttca tttttaaaac ctaatcctac cgtcaaagcg cccagtgcca aggcaaacag
    18841 catagcgacc attgagagca tttgtgtata ttcacgaata cgaaagttta actgtgacaa
    18901 tgtgaaattg ttcaattttt tcaatgaaat ctgttctgat ttctttagta atgataaaaa
    18961 gaaaatgatc acagaatgga aaatgaaata agttcctaat acgatcgtaa ctaaggctac
    19021 ccctatacca aagacttgat aggtccccac gtgtttcatc atatagtaac cgcagcctag
    19081 aaaagcaatt cccagtacta cttcaaggaa aaacaagaat ttatgctgct tgattcttgt
    19141 tggtgtctga tccgcacgaa tcaatgctaa aatcggtttt ttgacaatcg aaaaagcatt
    19201 gacaacagca gctaataaaa acaaaacagc aaaaaacaaa acagtgatca acaacccgtg
    19261 aatactaaaa ggtgtaaaat gcgaaatatt gagatctaac tgatccacta ataatcggtg
    19321 gacgatactt gtcaatccta caccgacagc tgaacccact aaagtagctg cgatccctac
    19381 taagaatgtt tcagaaaaaa tcatctgtgc gatttttctg ccttttgctc ccagcatcat
    19441 aaacattgca tagtcttttt gccgcatcgt catcaaaaag gaatttgcat ataaaatata
    19501 aacgaatgtg atgatcccta gtaaaacaga accgaatcgg aaaatgataa ctgtagccgc
    19561 aacgatcgta ttacttttca aaaaagcttc gttgcttgcc attgattcaa acatgtaaaa
    19621 aatagcagat gccataacta atcctgagaa taacaccaag tagtctctta aacggctctt
    19681 gatcccagta agtgataatt tccaaagcat agtcaatctc cccctactgt tccaagtttc
    19741 caagaataga tagtatttct cgatagaagg aatcacggct ttgatctcca cgtttcactt
    19801 cttgatggat accgccatcc ttgatgaata aaatacgttg gcaataactt gcagaaaacg
    19861 gatcatgcgt cacaagaaga atcgatacat gatcttttgt attcaattcg tccatcgtat
    19921 ctaaaagatc ccgggcactt ttggaatcca gcgcacctgt aggctcatcc cctaatagaa
    19981 tcgttggttg tgtgatcaat gcacgtgcgg cggcgacccg ttgtttttgt ccaccggaaa
    20041 tctcagaagg atagctttcc aaaatatgag agatggataa acgttctgca attttttgga
    20101 cacgttgctt gatttctttt ggtctgacgc cttgtaaaga aagaggaaca gcgatatttt
    20161 cttgtgctgt caagctttct aataaattga aatcttggaa aataaagcca atctcattcg
    20221 cacgaaaatc tgctagttga tttcctttta atgtggtcac atctttttga ttgattcgga
    20281 tatgcccatc tgttggttta tctaatgtgg ataaaatatt caaaagtgtc gacttaccag
    20341 aaccagaagc gcccatgatc ccaataaatt cgcctttttc tacatcgaag ctgatgccgc
    20401 ttaatgcttg cgtctttttc tcattgtttt ttccgtatac ttttgttaca ttctgtactt
    20461 cgactatttt gttcatttct ttccctaccc tttaattagt ttttccagtg ctgttttcgg
    20521 cacgtctttt ttttcgactt cttcatacga agtgacacct ttatttttgt tccaggtgat
    20581 ttttaaatat gctcctttac gaagcggtcg agtcaattgt cccttgaagt ccagttcttt
    20641 ttccttaccc tctttcgtat agccaggcag gatatatcta tagttgactg tttcttgtcc
    20701 agagtctgat tttgaaactg tttttgtacc atctgtcgta atttgtatat agtattcttc
    20761 tccacccata actacgtaat ctgcgatttt cacccctgca agtaccacaa cgatgaaaac
    20821 aagtagaccg atcagaagtt ttttcacttt ttccccttct ctcttacttt atatactgat
    20881 tatagaaaaa agcgaacaat tctgccttcg aatcaactat cattcttctt tcaattttgt
    20941 cattttcttt aaaacaacta aaaaaagagt tcaagacaat aatccgtcct aaactccttc
    21001 ttcctatctt acaaaaagta tgtcacttac ggtctttcat gtcgcctgta ttgataacag
    21061 gttgcgttcc tttgtctgta atgattgaga caagtaaatt attgatcaat tggactttcc
    21121 gatcatcggt gaaattgatt tcttgtccat cttcgatttg ctctaaggcc atttgagtga
    21181 ttgtgacagc tccttcaaca atggtttgtc gagcagacaa aatggctttt gcttgttgac
    21241 gttggagcat ggcactagcg atttctgttg cataggctaa atggttcaag cgtgtttcga
    21301 ttacttcgac acctgctact gctaaacgct cttgcagctc tttttgcaac tcgtcagaca
    21361 ctgccgtcgt gtttcctcga agcgtcaaat cattctcatt gaatgtatca tacgggtatt
    21421 ggctagcgat atgccgaatg gctgtctcac tttggatttc tacaaaatct tgataatacg
    21481 ctacatcgaa taatgccttt gctgtatcaa cgactttaaa gactactact gctgagattt
    21541 cgatggggtt tccatccaaa tcattgactt ttaaaacaga actattgaaa ttccgaactt
    21601 tcaacgaaac agtcattttt tgtgccaaag gtatcgtaag gaaaaagcca ttttctcgaa
    21661 tcgtacctaa atattgtcca aaaaacaaaa ttacttttgc ttgattagga ctgactacag
    21721 ttgccgaact taacaacaat aacgtgatca accaaagaaa aatacttaaa aaaagtgccc
    21781 aaactttcgc ttgccacata cctaaataga agaaaaacaa tccaactaaa gctaatacga
    21841 ccaatccgac aatccctgca taaccattga tataaaatgc tcttttttct ctcatgctac
    21901 ttcctgcgct cctttatcct tcaataaata tctaatgtta cttttttaat ttttttttcg
    21961 aatacgcgcc attacacctt ctagttctaa ctctttgtct tcagtgatgt accaaccgct
    22021 tgcctgtgtc cctccggctg cctgcggtaa ataatccaat tttgttcgaa cccagtgctt
    22081 ttcttctgta aaatagtctt ctaccaagac ctctagatcc atccctgctg aaagaggcaa
    22141 atcttcccga acagatttaa agataaatcg ttccttcttc ccatcatact tcaatattcc
    22201 tgtatcgata atcggtaaag aataataatc cagctctttc ttcaccgtca ataaatgttt
    22261 gaaaacttca tggtacactt gctctaattg gcgaccttct gaattgttcg ggtaattaac
    22321 catcactttt tctttgtctg gatcatagaa ggtttggctt agttgagtga tataagtatg
    22381 taatctttcc atttctgttt ttaacttttc tctttgacct tcttctacct tcatatactc
    22441 tttcaccctg ttttcttttt agatattttc tttcttattt tactatagtt atgtgcgtta
    22501 agcgatgaaa aacagcaaag attggaagga tctttgctgt tttttcttaa aatatccagt
    22561 tgagtacagg atcaatctgt ttcattgtcc tcttgatccg tcgtaatatt gatcgatgtg
    22621 tctttagcag tgatctttag ctttttctgt ccttgttcta acaaagtatt tgttattggc
    22681 tggtagtctt tttcaatata agattcacca gacgtttgga tagtatagcc actgttttcc
    22741 atctcatgca aagataaatt gccaccgttt aggatgactt ttccttcttt gctgatcaaa
    22801 ctgtcttcta gatggaagtt gctgttttca cctgtgacga tcaagttatc cacattggcc
    22861 tcatctaatc gaagtgagcc taattcatct ttcgcagtta ttgttcctcc tgtaaattca
    22921 ttgaacgata cccagccatc atgtgtctta gtattcactt ttttgattga tacttcgttg
    22981 atatcaattg cactattatt cccttcgatt gtcaattcag ataattcatg atctgcaggg
    23041 acaacaatag tgatttgtgc acttgtgtct tctaaactaa tgattgcacc tgttgatttt
    23101 ttgactgcat tcacagtcaa cacgccattt ttctccttta tttctggctt ttctgtctta
    23161 tcataagtcg tttttatctc aaaatccaat ccgcgtatga ccgaaactgt ttgattttct
    23221 gcatggatga cgattttgtt tgcatccttg attttttttg tctcagtaac catatcgatc
    23281 aaccgaggac cattatccca agtcagactc ttttgagcgc ctaatgtata agttgcacct
    23341 gctaggaggc caccagtaag catcagacca ataccggtaa tcaaaaaatg tttcaatctc
    23401 aatttatgtg tcctccttca aacgcccgct gaatgcagat ctctttttgt aataaaacgt
    23461 cgtcccatcc atttaacaaa gttcatcatg acataaaaaa gcccttttgt tcctttcagc
    23521 aacagtggcg aaataaatac tgcgcttcct gtggcgaaca gaccgacacc gataaagaat
    23581 aatccactca gaatcgattg tccaaacaca ctgattcctg agatgatcat gaataggcca
    23641 acacctaaga tactgataca taaaacatag atactaaaaa tgagcgctag taaagcaacc
    23701 aatagtcccc caataaccaa tataaacccc agtgctagtg gaatgaggac aggagaagca
    23761 aataaaccga taatgattaa ccaaatcagg cgaatttgtc tttttggatt tttcactaac
    23821 tcgttttctg cttgttcttc ttctgaaaag taactgattt ttaattttaa ggcaaactgc
    23881 tttggtgtac catattcatc aatgatctga tctaatgttt ttccagaatc taaaaaatat
    23941 tcctcataat actggatcaa atcaaaacga tcgtcttcag gaatttcttg aagatgatcc
    24001 acaacttcat tcaaatattc attcatttgt gctctcctcc aataaccggt ctaaagaatc
    24061 tcgaaaaaca atccattcat caataatttc ttctaaatga cgacttccca ttggtgtcaa
    24121 cgagtaatat cgacggtttc tgccttcaaa aggttcatca taggtctcaa gatatccttc
    24181 ttttttcaat cttctcaaaa ccggatatag tgtagattca ctgacagaga gactttcttg
    24241 tacgattttt gttaaggcat acccatacat atcttccttg cttaatgctg ctagcacagt
    24301 accatcaaga agaacagttg gaatctggat gtgcattacg tcaccttcta ttctcaagtg
    24361 taatatttta tttcaatcta tattatacaa catataatat agtttcaaaa tcagtttgtc
    24421 aaatacaaaa aaactgacta aaagatttga tcctttttag tcagcaaaaa atggcttctc
    24481 tttgattttt attataacag tggcataatc caatttgtcc acatccagct cagtggcatg
    24541 ataacgatca ttgcaggtat catgtcagct actgggaaca ttttcacgtt gatcattcta
    24601 aaaccggtag cgaccatcaa gaatccgccg caagatttaa aatctaagat catgtctggt
    24661 gtagtcaatg gataaataaa ttttgccaat aagaacaaaa tataaaaaat aatgaattgg
    24721 ggaattgcta tcacagaaac gacataccct aaattacacg caaaaatagc tgctgtgaaa
    24781 aaatcaagga cagatttaga aatcaaaatc gtactgtctc ctgtcatccc agaatctaaa
    24841 cttccataga tccccgtacc acttgcacaa aatagaacaa tgaccgtcac taatgtgctg
    24901 ataaattcat cgtgggtcat accaagcttt tcactaggga agattttaga aataggtact
    24961 tgcatcagcg cagccccctt atttatccca ttacctaaat gaacaatcaa accaatcgct
    25021 gttcctatca ctaaagcaaa aataacagcc ggcatatttt tcatcggcgc aatggaatag
    25081 attcccatcc ccatcgaaca cacaccaaaa accatcgtca gctgtgcttt aaaatgttca
    25141 cttaatttat ttcctactaa tccgccaatt agtccgccaa acaaaacgga acctacattg
    25201 atcaaaactc cagttggcat caaaaaactc ctctcttttt ctacgaagcg aaaaaaatca
    25261 gaaaaatttc tgtaattatt gctttcgctg caagaaagat tgtaacagac agagaagatt
    25321 acaccaattc attttttgtg ttaaagtatt ctttattgga ataagtagga ggaatatgat
    25381 ggatatccat aaattcgaag tttttcttga tttagccgaa acaatgaatt tcaccaaaac
    25441 tgctgatcga caattcacca cccaaggaaa tatttctaaa cagattcttt cgttagaaac
    25501 agaattagac gtcaaattat tcgaacgcgc ccatagaaaa atcgaattga ccgaagctgg
    25561 aagcttattg ctcccatatg taaaaaatgt cgtagaacaa taccatgcta tgcaagaagt
    25621 gcttgaaacc tatacgaaag acaacaatct ttcattaaat atcttaacga taccgacaat
    25681 gatcaattat aaaggttttt ccaaaatcac cgagtttttg aaacgccatc ctgaatttac
    25741 agtccagttg aaagaagtgg aaagtgtcga attaacttac aatgacgcca atgaacatag
    25801 tgacacgatc cactttgcta gaagtttcca ggccccacca agttcgattg agtggttgcc
    25861 tactgaaaca gacgattttg tagcagttct acctaaaaat catcctttag ctagtaaaaa
    25921 gaaattggat ctaagcgaac tgaaaaagga gaactttttg ctccttggcc ccactacgaa
    25981 cttgtatcaa cctgtactag atctgtgtcg cgaagctgga tttgaaccaa aaatctctta
    26041 taaaggagca agaatcgact tgatcatcaa tatgattgca aatgacatgg ggattgctat
    26101 tgttatggaa aaaacagtca agaatctatt aaaagaaaat actgtgattc tccctatttc
    26161 tccaacaaca gagagttatc ttgcatttac tcgtaaagtc ggtgagcatt ctttggcttc
    26221 agatacattt tgggagtatt taaatcaaga agaaaactaa gccctacatt ttctgtccat
    26281 ctatccaccc aaaaaaagag agcgacgcat gactttcgct ctctttcttg catcatgtcc
    26341 ttgtttcaat gacacctcta acatttctcg tagttcaata agaaagcagc gatttttatg
    26401 ccaaaagaac cgtaagaaca tttccctaat cacaaaaaaa cgactaaaaa cccctaaaaa
    26461 ccttcaatag aatttttagg ggttttattc tttttcctat tgtttactta accgtatcat
    26521 tgctgtcgtt cctactcctt cgatactgct ataatcaata cgtccatcat gcagttctag
    26581 aattttttta accagtgaaa gtcctagccc attcccagaa atttgacgac ttgtatctcc
    26641 ttgataaaat ttttcaaaca ttcgatctct ggtctcttca ttcattccta cacctgaatc
    26701 ggtcacttcc agtacaatct ctgtggctgt ctcaaatagt ttgatatgaa tctgtccatt
    26761 gatttgattg tactttatgg cgttatccat gatattcagc cacacttggt acaaaaactc
    26821 ttcattgcct gtgtaattta ctgcagcaag ttcgatatcc aattctagct gttctttctc
    26881 ccatttaggc tgaaaaaaaa cgattacttc tctgatttgt tcatctaatc gatactcttt
    26941 cttttccagt tggatacgct ggttttccag tttgttcaat tttaagatgt tctctgttaa
    27001 ttgtgaaagc tgcgtgatac tttcgataat ccgatataaa aatatttggc gttcttcgtc
    27061 agagagattt ggggcttgta acaattgaac atatccttgg attgttgcta gtggtgtttt
    27121 gaattcatgg gatacactgg acacaaagtc attcctcagt gtctcgatac tattgagttc
    27181 ttggaccata acgttgaaat ctttatacag ttgctgtact tctgctactt tctgctgttc
    27241 atccattcga atcgaaaaat ctcccgttgc taccagactc atatttgtcc ctagcgcact
    27301 gattggatgc aggatacgcc gcccaacaaa aatcgatatt cctgtaccca cgaccatact
    27361 gaaccccgca aagacgaata acgggtataa cgttggtttt ccagccgatt cagcaggcga
    27421 gatagaatgt cgagacaata agaaaataaa accgagaaaa cacagcagtg tcactaagat
    27481 cgaaatgaag acaatactag caaaatagat ccataattgt gaaaatagct tttttttcat
    27541 ctttaaataa ccgccttata gcctagtccc cgtactgtga tgatttgaaa atcttccgtc
    27601 ttttcaaaac gggtccttaa acgtttgata tgtacatcga tcgttcgttc ttctgtattc
    27661 gtatctaatc cccaaatatc atccatcaac tgttggcgag tgaagatctt gttgggataa
    27721 gacagtaatt tatacagaag cagaaattct ttttgaggca gaatcaacga atgctgatct
    27781 tgtaacactg tataagcatc tagctctaat tttgtttgtc cgattatcaa gctactgctg
    27841 taattgatct ttgaacgtcg aagcaatgct tccacacgta ggatcatctc attgacatcg
    27901 atgggttttg tcatataatc atctgctcct aatttgaacc cgcgtttctt atcctcaaaa
    27961 tcggcctttg ccgtaatcat tagaacaggt gtgtcaaatc tggtgctacg taatgagtct
    28021 agcaagtcat agccatccat tttcggcatc atgatatctg taatgattaa ttctatacgt
    28081 gtcgcttcta gttttttcag cgcatcctct ccattcaatg cggtgatgac tgaaaagccc
    28141 gctcgttcca acacagaacg gtaaagcaac tgtaattgcg gatcatcttc tactactaaa
    28201 atacgattca ttgatctccc tctgtttttt gaaaaatttc tagatttttt cttgtagttc
    28261 atcttcagtt aacatttatt tcgtatacta cgatcattgt tctgatatac ttattagtat
    28321 accgaatatt tcaatacggg agaagggtga ttatgcttca attaaaagat ataaaaaaat
    28381 attataaagt cggcgaaacc accaccaaag cattggatgg tgtgtctgtc gctttcagac
    28441 aaaaagaatt cgtagcgatt ttaggtccta gtggttctgg taaaacgact atgctgaatg
    28501 tgattggtgg actagataat tatgattccg gtgatatggt aatcaacgga aagtctacta
    28561 aagactttaa ggacagtgac tgggatgcct accgaaacaa ctctatcggt ttcatttttc
    28621 aaagttacaa cttgattggt catctaggca ttattgaaaa cgttgaactt gggatgacat
    28681 taagtggtgt ttctaaagac gaaaaacgaa aacgggcaga agatgcattg caccgagtcg
    28741 gcttgacaaa tcatatgcat aaaaagccaa atcagttatc tggtggacaa atgcagcgag
    28801 tggccatcgc tcgagcacta gccaatgacc cagatatcct tttgtgcgat gaaccaaccg
    28861 gagcgttaga tacagaaaca agtatccaga tcatggaatt gatccaagag ttatcgaaag
    28921 aaaaattagt gatcatggtc acacataatc ctgaactggc ccatcaatac gcagatcgaa
    28981 tcattgaatt ttctgatggt aagatcttaa cagattccca tcctcacatc gaacgaccaa
    29041 aagatgatca atttaactta cgcagaacaa agatgagttt ttggacagcg ttaaagcttt
    29101 ccttcaacaa tatccgaaca aaaaaaggac gtactttctt gacctccttt gcttccagta
    29161 ttgggatcat cggaatcgcg atcgttctgt ccctttcttc tggattccaa aaacaaatcg
    29221 ataacacgca agctgaaacg atggcgaaat ttccgattac tatttctaag gtaacgacta
    29281 accagactcg tgacgatgcc ggattgggtg caagcaaagc ggattatcca gacagcaaaa
    29341 cgattactgc aaaagtcagc gaagaagata aagcacagca cacgaataag attgatcaaa
    29401 catacgtcga ttacgtaaca gacatcgatc ctaacttaag taataatatc ggatttaccc
    29461 gtactacagg aatcaatctt ttacgtgatg taaatggcaa agtacagcct gtcagcttct
    29521 cgaatcaaaa tcctgatacg gaatctcttt ctttatctag tacgatgtca gcaatgacag
    29581 gtgtgggagt gtcaagtttc cctacacagc ttgacactag caaagaaaac tttttaaaag
    29641 acaattattc tttacttgcc ggaagttatc cagcctcagc aacagatgtc gtgctgatcg
    29701 tagacggcaa taataatact aatatcaacg cattgaagaa tcttggattt gatgtgaaag
    29761 aagacgaaaa acttgatttt gatgatatcg ttggtacaac attcaaatta gtaaacaaca
    29821 atacttacta tacaaaactt ccaactggga attttatccc taatacagat tatgatgcga
    29881 tgtatcagaa tgcttctgat gaattgaaga tctcggggat cctacgcgtg aaatcttctt
    29941 ctacaatgaa tctcttatct ccaggaatcg cttatagcga tcaattaacg actcaaatcg
    30001 tcaacgaaaa caaagaatca gaaatcgtca aagctcaaag agacagtggt gtaaatgtct
    30061 taactactga aaaagttgac gaaaatgcca aacaaacatt gcttagttat ttaggtggag
    30121 acagcttgcc ttcaagtatc atgatttatc cgaacaattt tgaagacaaa gaaaagatct
    30181 tggattatct agatgattac aataaaggca aatcagatga agataaaatc atttatactg
    30241 atttagctgg aacgatgact gaactgactg gcggattgat ggatgctatc acttatgtcc
    30301 ttattgcttt tgcagggatc tctttagtaa caagtatgat catgatcagt atcattactt
    30361 atacatctgt gattgaacgg acaaaagaaa tcggtgtact aaaagcttta ggtgcacgta
    30421 aaaaagacat cactcgcgta tttgacgcag aaacgtgtat tttaggtatt tcttctggga
    30481 tattaggtgt gtttattgca tggctagcta cgttccctat caatagcatc ttatacaaca
    30541 tgacggatct aaaaaatgtt gctcaactaa atcctgtcca tgcgattatt ctagtgatcg
    30601 tctctactat attgacgatg cttggcggtc atcttcctgc acgaatggca gcgaaaaaag
    30661 acgccgctat cgctttgcgt gcagaataag gttgtgacaa ccacatttag atttgagtca
    30721 taagagcgct gaaatagtag aaaacagcaa gaaacgagga agtaatatgt tccttgtttc
    30781 gcgctgtttt ttttaattat tttttataat tctggtatac ttttctttcc tttgtaccac
    30841 aactcttctg gcgtatacct gtcttttcca tttatgaata ctgttccatc tgcttcaatc
    30901 gttacttcag tcccaatcca catattacga gaaagtgcga gaagattttt tctttttcct
    30961 cttccttttt ttccaaattg caaggcatcg gttatctctt ctgtccaatg agatttcacg
    31021 tattttactt ctccgttttc aaatgtaact ttcaaaatat tcgctatatt ttccactttt
    31081 actgctttag gaaatgactc ctccattttt ttcactttcc ttcctccaac actaagtatg
    31141 cgctttcttt tagtgataag tatatcatag tttattctat tatcaaaaaa acgcatccat
    31201 tccattgtag aatactttac cgaacaagtt gaattgtttt cctctttttc accttttact
    31261 atagataggt aaagacaact aaggaggaat ctctcatgac agatcaaccg tatgatttaa
    31321 gaaaagtcat cgaagaacta aaaacacttc caggtcaata tcacgaaaca gatattgaaa
    31381 tcgatcctga agcagaatta tctggtgttt accgttatat cggtgctggc ggtacagtaa
    31441 aacgtccgac tcaagaagga ccagctatga ctttcaacaa tatcaaaggt ttccccggca
    31501 cacgtgtgaa catcggaaca atggctagtc gtaaacgtgt aggtgaaatt ttgcaccatg
    31561 attatcgaac acttggtcgt ttcttgaaag acgctgtaga aaatccaatc aaacctgtga
    31621 aagtagacaa agcagacgct ccagcacaag aagtcgttca tctagctacc gatgcagact
    31681 tcgatattcg caacattttg cctgcaccta caaatactcc tgaagatgct ggtccataca
    31741 tcacaatggg tgtagtctta ggatcagatc cagaaaaaac aatgagcgat gtaacgatcc
    31801 atcgtatggt tctagaagat aaagatacga tcggtatgta catcatgcct ggcggacgcc
    31861 acattggtca cttccaaaaa caattcgaag ccttgaataa accaatgcct atcactatca
    31921 atattggttt agatccagca attgccattg gcacgacttt cgaaccacct accactccac
    31981 ttggctacaa tgaactatgg tgtgcaggag ctttgcgtaa cgaacctatt caaatcgttg
    32041 atggtatagc agtcgatgaa gtgggtattg ctcgtgctga attcatcatt gaagcagaaa
    32101 tcatgccaaa tgaaacaatg caagaagata tcaacacgaa ctcaggaaaa gcaatgccag
    32161 aatttcctgg ctatactggg gatgctaatc cagctgtaca agtagtgaaa gtcaaagcag
    32221 ttactcaccg aaaagacaat ccaatcatgc aaacaacgat tggtcccagt gaagaacacg
    32281 tatctatggc cggtattcct acagaagcaa gtattcttgc cttggtcgat aaagctattc
    32341 caggaaaagt agtaaatgtc tacaatcctc ctgcaggtgg tggtaaattg atgaccatca
    32401 tgcaaatccg taaagaaaac gaagcggatg aaggtattca gcgtcaagca gctattcttg
    32461 ctttatcagc cttcaaagaa ttgaagacag tcattttagt cgatgaagat gttgatattt
    32521 tcgacatgaa cgatgtagtt tggactttca acactcgttt ccaaggagat aaagatatca
    32581 tcgtgatccc aggaatgagg aaccatccat tggacccatc agaattacca gaatataatc
    32641 ctggctctat tcgtttccgt gggataagtg caaaaactat ctttgacggt acagttcctt
    32701 tcgatatgaa agaacatttt gtacgtgcaa aattccaaga agtagaagat tgggaaaaat
    32761 atttgaaata atgaatgatc tgcaactgtt ttgacatcat aaaaaggagt gcggaaaatg
    32821 gaacaattgg cacaacggaa gaaaaaaatc gtgattggtg taagtggcgc ttcaggcacc
    32881 atttatgcca tcaacctagt gaagaaacta aaagaatatc cgatgataga aacacacgga
    32941 atcatcagtc catgggcaaa acagaactta aagctggaat ccgacttatc actaactgaa
    33001 ttcgaaagcc tgtttgatta ccattattca aacaaagatt taggtgctgc tgtcgccagc
    33061 ggatcatttt tgaccgatgg aatgatcatc gtaccggcaa gtatgaaaac agtcgcaggt
    33121 atctctgttg gtttaggcga caacctgatt gcacgtgctg ctgatgtaac aatgaaggag
    33181 caacgaaagt tagtcattgt tcctcgtgaa acgccattaa atgccattca cttggaaaac
    33241 ttgactaaat tagcacgact aggtgtgcaa atcataccac caattcctgc tttttataat
    33301 cagcctcaaa cgatccaaga tcttgttaat caccatacaa tgaaactttt ggatcaattt
    33361 gaaattgtaa atgagcattc aaaacgttgg cagggtgatt aatatggaaa aagaaacgat
    33421 agttgaagta accaaactag gtttcacgat ccaagctgct gttaaagtaa tcggtaaaga
    33481 cttattgatc actttaacag gcggagatac accacatatc ggaacagtca ctacattttc
    33541 tcgtgataca gagatgcaaa ctgtacgttt ccctagccac gatggtcggt tccataaaga
    33601 cgatgtctta gccgaaaaaa tagctgtgat catcaaaact gccgttccgg gaagttgtac
    33661 gatcacttcc ggtatccatg ttgaccatat ctccaatgca caaatcaacg cctcttttcc
    33721 gatgtcagaa gagttaggtt acaagatttt agattggttg gaaaaaatag atttccatat
    33781 caaagaacca gtttattata aagatggtga aaaaccatta tgaaagaaga ggttgtgaaa
    33841 tcagcgttat gacctgagta tgagagaaaa aaatggaaaa atagcttctc atattttgcc
    33901 gtttttgagc taataccgag ggacagctga ttgaacgccg tttatcaaga ggttgtgata
    33961 aagccgcttc gtttcgagta gtaagaaaaa ttttgtaaac atgggtttcc acatttttgc
    34021 ataaatttga cttactaccg agaaactggc ttttgaacac cgtttatcaa gaggttgtga
    34081 cacgtctttt gtcacaacct cttttatttt tgcttcactg taactgctac aatatcaccg
    34141 atttcttttc cgatgttttt acgaatatct tttcgtagtc caaggatgta gcagactgaa
    34201 ccatctggat ttttcacgcc catattcacg atactgcctt catacggcac attgtcaaaa
    34261 gttgcttgga ctttaactct tccagcaccg aattcttttc ttatatcata cggaaaaata
    34321 atatatgccc cgcccttgcc gacttcggaa gcatagattt ttgattcaaa agaataaatt
    34381 tccctcattt tatttctcct attttttaca tctagtatag catagcaaaa aaaagaagga
    34441 actgtgacaa aagtcttgtc gcagttcctt ttttcgaata aacggtgttc tcctgccaac
    34501 tcctcggtca caagtcacaa tagtcaacaa acatgagaag ctgttttttg aaattgctcc
    34561 ttgtgactca gagttaaacg gcaggctcac aacctcttcc ttaaacggtg ttcaaaagct
    34621 tgcatctacg gcactaagcc caatcagatg aaaaatatgg agtgctattt ttatctgatt
    34681 gttcttactg cttgatgcag agcagctttt tcacaacctc ctacatggtg ttcaaaatat
    34741 tattcgcctt ttgcttcttt cactaatttt gcgaatgctt gttgttggaa ttcagcagct
    34801 aaggctttcg tacgttgttc ttgctctgct ttgctcattt ttggattttc agtcattgct
    34861 tttaccatac cgtcttgaac ataagctttt gcttcacttt ccatcgtact ttgctgtttc
    34921 ttcactaatt cagctaactt ggctgcttgg tccgtactta attctaccca tgtctctggg
    34981 attttgaatg tattcactcg gctgtcatat tcgtgattgt tatcagcaat attgaaccag
    35041 aatttataca tgtcgttttt gtattcccaa taagtagttt tcgtcacttt ttcagcatcg
    35101 ccgtctgtct tttctacttt atttgtttcg ttatccgtac cagttgcttt tggtttttct
    35161 tgtttttcat ttgttcggta aagatacact ttttcttttc cattccctaa agctttatac
    35221 aaaagcatat ctgctccttg ggaatcagca ctggaaacaa ttttttctgt ttttgtttcc
    35281 gttacttttt ccattccaaa gtgattggac aaattagcga cgatcaaact tagtgaagcg
    35341 acgaagatta gtccgaaaat caaagataaa aaggtttgcc atgttttttt agcgaacacg
    35401 ttcgttaaag caaaagcaag caagctgaca atcaaaactc caataatcat gcattatccc
    35461 ccgctttcat tagaacaggt tcttttttct tcaataaaaa ggcaataata aagccaagaa
    35521 tcccaaagat gatcgctacg ataaacgcgg catggtaacc tgacagtgtg gcattgattg
    35581 cctgatcttt ataagctaat ggcgtattat ccaatacaga tttgcttggg atatttgctt
    35641 ttgtcacatt cgtcaacaca ctgatcaaaa tagctgtacc aatcgagctt gcgatttgac
    35701 ggaatgtatt atttaccgct gtcccatgac tgatcaagtt atttggcaat gcattcatac
    35761 cagaagtcgt taccggcatc atgaccatgg agatcccaaa catacggatc gcataaagga
    35821 tcacgatata taaaactgga gtcgtttttg tcaagaaagc aaatggtgca gttgccgctg
    35881 tcaaaatgaa catccctgtg atggctaaac gtttcgcgcc gtatttatcg aaaatcgcac
    35941 ccgtcacagg catcatagcc cccatgatca atgcacccgg caacaacatc aagccagaat
    36001 ggaatgctga ttctccacga atattttgaa tatacaatgg tacgaccatt tctgccccta
    36061 ccatcgccat atttgttaca ccagctaaaa cagctgcaat cgtgaatgta gatgatttga
    36121 atacacgaag ttccaagaat ggatgttcca aatgtaattg acgccatgag aacaaggcga
    36181 tgaaaatcac accaacaact aagaaaccaa ttactttcaa gcttccccag ccgtcatctc
    36241 ctacactaga aaatccgtaa agtaaactac cgaatccaat cgttgataaa atagcggata
    36301 aaatatcaat gctaggattt gacaatggaa taacactttt cattaggaag aatgctaaaa
    36361 ccaagacaag aacaacgatt ggcagtacca taccaaacaa gtcacgccaa tggtagttat
    36421 caatgatata accagataat gtagggccta aagcaggagc aagtccaata acgatccctg
    36481 acatccccat tgctgatcct cttttttctg gcgggaaaat agatagcatg atattttgca
    36541 ataatggcat cgatactccc acaccgcaag cttggatcaa acgaccgatt agtaatgtac
    36601 taaaattagg tgctgtaaag caagtaatcg ttccgatcaa aaagatcgtc atggcagaaa
    36661 gatataaatt tcttgaactg aatttattga tcagccatgc tgttattggg atcatgatcc
    36721 cgttgactag caagaaacca gtcgttaacc attgcacatc agacgctgaa atatcgaaag
    36781 ctttcatcaa tgtaggaaaa gctgtcgtca ataaggtctg attcaaaacg gtacaaaatg
    36841 taccaattaa taagacaaca actaaaagtg tccgattata tggttttccg taaatatcta
    36901 cgggttggtt gttactcata tttctccttc tttctgaatt ttttctgaaa ctactagaat
    36961 actttagtcc taaattcgct atttgtcaac ctacttgaca cataagttaa tacggatata
    37021 attaagggaa gcaagaggac aaaaggagtg acaaaaatgg ttggggcttc ccttaaacgt
    37081 ttgttggaaa atgatcaatt ggttgttggc atcagtgaat taagtgatat cgtaggtgtg
    37141 tctccacgtc aattaaggta ttgggaacaa aagggattca ttcgttcgat cgaagctgat
    37201 gcgaattgtc ctagaaaata tcgtttacct acagtcataa aagtagaact gatcaaaaaa
    37261 tatttagatg acggatttac tttgtcaaaa gctgcagaaa aggcagaaat ccgccaaaag
    37321 aaaatgcacc atgtccgtaa agttttttca aaagcaatca aagatatcga attgatcgac
    37381 gaacgctata cgattttaca aatcggtaac ttcaaagaag agaatgctaa gatgtacatc
    37441 attcatgaca acgagacaga cgaattaact tacaagctcc ttcctgtcga tgaaaaagct
    37501 gactacgaac agttgttaaa agaactctaa acgccactaa tctcctaagt accaagcttt
    37561 ttaataagta gatgctacat aaatacttga aaaaaggcct gtttgaacat aagaatatcc
    37621 gaacggtgat ctgcgtttct ttcatataga aaggaattct ccatcactgt tcggatattt
    37681 ttttattttt ttcggttact ttcttctaat acatctgtta gccaatttgc atattctgtt
    37741 tcccgattga tcgcatgcgc taaaatcagg tagtgtccgt aattttcatg tttttctttt
    37801 tcagtaggaa agatcgtttt ttttcgctct aatagatgaa gtcgtttttc ttcatgaagg
    37861 tcacgctgct gctgaataat ttctactaat gccggatcat tcacgtcttt gacgaaatac
    37921 aatttcagaa caaattcgtc tcgattaacc ggtagttcat tggtgggtgt atgaatccac
    37981 tctgccaatt gttccttccc ttcttctgtt aattcataaa ctttcttttc caatttttca
    38041 cctgtgatct ctacttgatg ctgaatgatt ccttgctctt ccatttttgc aagttcagga
    38101 taaatctgac tatgttttgc ttgccaaaat tctcctattt catttttgaa cgattgattc
    38161 aattcatatc ctgtcatctt cttcttactt aataacccta acaaaatata tcgaagtgta
    38221 ttttttcttg ccatcagttt tccctccttg acaaatcttt aaatccattc tatcataaat
    38281 gagtaatcga aaacatgtag tttattacat gttttaattt ataaggagat gcttaaacat
    38341 gaaagaattt aaagaattgg aagattttat tggaactcac tttatctata cgtatgacaa
    38401 tggttgggaa tatgaatggt atgccaaaaa tgaccatact gttgattacc gtatccatgg
    38461 cggaatggtc aaaggccgtt gggtaaaaga ccaagaagct gatatcgtta aattgacgga
    38521 cggcgtattc aaaatcactt ggacagagcc aacagggaca gacgtggcat tggactttat
    38581 gccaaatgaa aagaaacttc acggaatgat ctttttccct aaatgggttg aagaacatcc
    38641 agaaatcact gttactttcc aaaacgaaca tatcgcagaa atggaagcag ctcgtgaaaa
    38701 atatgaaact tatccaaaat tacttgttcc tgaatttgct acgatcactt atatgggtga
    38761 tgcaggtata gacaatgaag atgttattag cgaagaacca tacgatggaa tgccagatga
    38821 tatccgtagc ggaaaatact tcgatgaaaa ttataaacga gtaaaataag gttgtgaaag
    38881 agaggttgtg aaatcagcgt tctgacctga gtattagaga aagaaacgga aaaatagttc
    38941 ctcatgtttt gccgtttttt gagctaatac cgagggtcag ctgattgaac accgtttatc
    39001 aagaggttgt gaaatcagcg ttatgctttg agtaataaga acgctagtta gaaaatagct
    39061 tttcatattt tctaggctag tgggcttatt accgagaagc agccgtttga acaccgttta
    39121 tcaagaggtt gtgaaatcag cgttttgacc tgagtattag agaaacaaat ggaaaaatag
    39181 ttcctcatat tttgccgttt tttgagctaa taccgagggt cagctgattg aacaccgttt
    39241 atcaaagatt gtaacaactg catattcaca cagttaaatt agtgacttca aaatgaaata
    39301 atgctcccag caaaaaatta ggctgggagc attatttcgt tattctgttc atcaaaaatc
    39361 agcgttttga ttccatttca tcacaagttc ctcctcattt actgcttcat ctttttgctg
    39421 tgtttgaatt gtaaaacctt gtgaaagata gaaatgaata gctgattgat ttttttgata
    39481 gactgtcaaa gtcagtgttt tattggtttc ttttattttt ttcattagtt gcgtaccgat
    39541 tctttgttgc cggtattccc ttttcacaaa gattcctgcg ataaactgat caatcacccc
    39601 agcaaaacca ataatttctt gatctatttc tgctaagtaa atcactgcat ctggtaaagc
    39661 tttcctaaca gattctactt gattctccca ataagttgat ggaatgaatt catgagaatc
    39721 caagttagca tgcagccaaa tcgatagaac agattccagt tctttggcag acaattttgt
    39781 tgttgtgcgg atcatttttt ctctccttac ttattcattg attttaaaat aaaaaccatt
    39841 tttttgaagc tcttttacaa gttttcgccc ctcaaaaaag tatatcttct cttgttttac
    39901 ttttctaata ccaaaagaaa cagcaacttt aggatcatca gctgaaacga ttcgataagt
    39961 tccaccaggc aattgatcca gcttgacttt cccatgatgg tcgctttgta ctgaaaacgg
    40021 cacaccattt ctagtaagtg tttttttctt atgtttcaaa atgaatgaac taccatttac
    40081 cggtttccct gacgaatcac taataataaa tgaaaaatca agcacttttt tacttaatct
    40141 atactgatag attagtcgtc cgataaacac taacagtatg actacagcta ttatcgttcc
    40201 tgcaagaata aaccattgcc gcatggttct ttcctgattt ccttttcctt cttctttttt
    40261 taccgattcg ttataaggaa tccgatgtcc tgtcactagc aaacgatgcg tgttgatcat
    40321 atacggcgta catgtaagca aggtaactaa gtcttctcct tctgaaatcg ttagaacaga
    40381 cgtgtcatct ggcagtacca cttgtatatt tttaacttga taagccaatt tctcccccaa
    40441 aacagtcaaa ataaacgtgt ctccgttttc taaacgatct aattcggtaa ataaccgtcg
    40501 attaggtaaa ccgctgtgag cagagatcac tgaatgcgtc gaatttccac caagcgggaa
    40561 agaggttcct tgcaagacgc ctgctccatt ttcaaggatc ctaccattga gccgatcata
    40621 aagtgaaata tttaattgga tcttaggtat attgatactt ccgatcagcc attcctctaa
    40681 ttggctggat gttgtacttt catttctgtt cttttcattg aaaggatcag taccaggatt
    40741 gaatccttgg tcagttaatc gttggttttt ctcctccatt ttctttcgct gcacttcaat
    40801 ttcagctgcg gtccgttttt gtacttgttc gatacgtttt tgatcaataa aactatttaa
    40861 agaatccaca taaaatggat ataaagcgat cagtaaccct acgacgatac atattaataa
    40921 aaacaaacga aacaaaagtc gacgagactg tttttgctta ctctgcttca catgtgtcct
    40981 cccttgcaag tttttttgtt ctttctttta ttatatgggt tcaggaaaaa aatagaaaat
    41041 gaaagccgat gaggttgtga aaaagctgtc ctgcatcaag taataagtac agcccaaaaa
    41101 aatagctact catatttttt gttgggttgg gcttattacc gcagatgcaa gcttttgaac
    41161 accgtttaag gaagaggttg tgaaaactgc gttatgcttt gagtaataag agcgctagtc
    41221 agaaaatagc ttctcatatt ttctaggcta gtgagcttat taccgagaag cagctgattg
    41281 aacaccgttt accgagaggt catgaaaaag ctactttgtt tcgagtatta agaaaaattc
    41341 tgtttcaaaa caaggagatg caacaaaact tatgtcgcat cctctctcct tagaactttc
    41401 acttatgttt ttcttgtaaa attcataaat attttcatga attttctaat ttcttgccta
    41461 cctctcgcat aggatatatg atgaatttat ctaaagtttg caaaggagtt cgacaattga
    41521 aaaaatatgg cccattttta gcaatttttt tcattgcttt ggcatttctc atgcctcatt
    41581 tattcacaca taaactaatt ttgggtgctg atgccccatt ccattacaat cggttctatg
    41641 atgccgcgca acaaattaaa tatggggatt tccattattt tccttccctt tatggattcc
    41701 agcaaagtgg caggatcgtg aatgccgttt acggcccatt tttcgcttat ttacaaggat
    41761 tgatcgtgtt gcttgcaggt agctggtttc attatcagat tctttcaaat ttcattcttt
    41821 atcttatttc aggattttct atgctgattt tactgagata tgtcaatgtt cgaaattggg
    41881 taagtgtacc agtagccgtt ttattcatga gtacgtattc tattcaatac tggtctatca
    41941 accaaggatt cactagctgg gggacttgtt tttatccttt atgtatgatc cctattgctg
    42001 atttcgtcct tcataaaaag ttccctgtta tcaaagtcgc tgtctcagtg ggacttatga
    42061 cacagatcca tttactgtct tcgatcatgt tagctttgat gtatatccct ttttatcttt
    42121 attacttttt taaccagact gaaaaaggaa aagcactgct tcaactgatt aagtcggtct
    42181 tgctttattt tgttctgaca gcaaatattt gggcaggatt agctattgtt tacagtggga
    42241 ataagattct tcctcccttt gttaacagag aaatgagtca aaaggcgata gatctggatg
    42301 gcagttattg gctccattac cctaaggcct ttcctatatt gatattatca ggttttttgc
    42361 tttttatttt ctttcaacaa aagaacacct tattccaaaa aatcgtgttg tacacaagtc
    42421 ttgttttctt ttttctttct actagcttga ttccatggac gacattgatc gaaaaaaatg
    42481 tgccttttat tagtttgatc cagtttccat ttcgattttt cgtgccattt acgctattgc
    42541 ttctacttta ccttgccctt tcactgaacc agtggtctga acaaaagtgg ttccgtcttt
    42601 taagtatatt tggcattctt attttttcag cacagacgat ccagaactta taccagcatc
    42661 tggaaaagtg ggaaaatgaa acatttgtca gtcgacatac ttatctattc gatacgccgg
    42721 aagaagcaag gaaaacattc ttcagcaaag atatgtctac cagcttgttc gttttccaaa
    42781 aaaccacacc tgactatctg ccaatctata aggagacaaa agacaataaa tacgaccggt
    42841 ataacgaaga aatactagaa aacgaaacaa cttttataaa aacacatcca ggcggtcttt
    42901 tgacaatcaa gtggaaaaac actggggaca aaactgttca tatccctgtt atcgtctacg
    42961 atcggactgt gctacagcaa aatggaaaaa cattgactga ttatgaagta acagatatcg
    43021 ggaccccaat cgtgaagcag caaaaaggaa tcaacgagct cacgcttcat tatcaaacgc
    43081 caatctattt ctatttcatt ctttctctta ctttgattgg ctggtttacc ttgctatgtt
    43141 tatttattta tcatagatac aagcttttac gtgcttaggc aaaagggata aatacatccg
    43201 atcaaaaaac tctccaaacg gtataatcgt ttggagagtt ttattttaat cagttttttt
    43261 atgttatatg ttatattttt tattcgttca catctaattc gatttccacc ccgtagtgat
    43321 cactgatgat tggactatcg atcccatcaa aaatccgttg atatttttta acctgcattc
    43381 cttcagggac gaaaataaaa tctatacgca atttttctgt attttgttcc caaccatcta
    43441 ttttcttttc cacagtagct gcttttcctt tttcattcgc gacaacatac gaatcttgaa
    43501 gaagaaggca actttctctt acagtataat aaccttgaga gtctactgga ttattgaaat
    43561 cacctaggaa aaaaagtggt acgcgagttt ccaaaaagta gttttccaag tttttccact
    43621 caaaataaaa gccacttttt ttatctgtcc accaagaaaa gtggcagctc gagacaaaaa
    43681 tgtcctgatc atctatcttt gttttcccaa tcaagatctt gcgtgtctga taatcttctt
    43741 tcttttgaaa ttgggagacg gtaaggacct gactttccaa tgtttttttc gtaagcagtg
    43801 catttccttc ttcatattta tcataaccga tgtggctcat ttcccaactc caaaaatact
    43861 cttttccgtg ttcctttaaa agctgaacta aacggtaggc aaaattatct ttacggatag
    43921 gtacttgatt ctttaccgga cagaacttca ttagcttcgc aggttctact tcttcagatt
    43981 ccagtaattg gttgatttct tgtaaagcaa tcacttcata atcttctaac aggatcttat
    44041 ctgctaattc ttgcaatttt ttctctggtt ctggctcaag ccagctatgc gtgttgagtg
    44101 tcatgaattt cattggtttt ctccttgtct tcatttcgaa acaaaagggt tgtgacaaaa
    44161 tttttgtcac aacctctcca gcaaatagtg ttctcctgct aactcctcag taataagctc
    44221 aatggaccag gagctatttt ttgtttggct gtttttatca cttggtgcag ggcagctttt
    44281 tcacgacctc tccactaaac agtattcaaa ctgctgcttc tcggtaataa gcccaaccaa
    44341 acgaaaaata ggaggagcta tttttgtttg gctgttctta tgacttgatg caggacagct
    44401 ttttcacaac ctctccttac attttaatgg agccgatcac tttaccagct gtcactgtac
    44461 ctaattgctt gatcactact tcttctactt tatcgtttgt aaatacgatc atgatcgttg
    44521 gatctttttc ttcgttttgg atcacatcaa gatccatctc agctaatttc gttcctgttc
    44581 ctacttcttg gccttctttg acagcaatct caaaagctgg ctgattcatt tggactgtat
    44641 cgattcccat atggatcaaa acttcgatac catctttcgt ttccagccca attgcatgtt
    44701 tgctagggaa aatacttgtc acttttccag cgatcggcgc aacaacttct cttgatgttg
    44761 gaataacagc aaagccgtca cccatcattt tttgtgagaa taccggatct tttacttcag
    44821 ataaaggaat cacttctcca gaagctgcgg aaactagttc ttgttctata cctaagtatt
    44881 gcttactacc tgcttgtcca tttcctgtag aaaccatttc tggctctgga atctctgctc
    44941 ctgattgcag cagatcttcg atatctgatt tcaagacatc tgcttttggt ccataaactg
    45001 cttggactcc attgtctttg acgatcaatc ccatcgcccc tgctcgtttc caggcttctt
    45061 cagtccctac tttttctcga tcatttacac ttacgcgtaa ccgagtcata caagcatcga
    45121 catctttgat attttctttt cctcccagca aatgaatgat ctggaccact tgctgatctg
    45181 ctgttcctgt tccgctgtta gatacaacgg tttcttcact gtcattgtcg taatttccgt
    45241 tacgtcccgg tgtagcaaag ttgaattttt tgatcaagaa atttgctaag aaatacgtaa
    45301 caacaccaaa agcgatcaca cacaacacga agttgataag atctccacct agacccgctt
    45361 tgatagctaa cggtgtccga gtcagcaatt cgatattccc aaatgaatgg acccgcaatg
    45421 gcaagatatc tgccatcgca aatgcagccc cttggatcac tgaataaatg acatataatg
    45481 gcacagcagc aaacataaac atgaactcca atggttctgt tacacctgtt agaaagacag
    45541 ccaacgctgc tgaaaaatac attgatttat atcttgcttt cttatcagga tcgacattac
    45601 gatacatcgc aaaagccatt cccatcaaga tacctgaaga accaatcatt tgtcctactt
    45661 tgaaacgagc cggcgtccag ttatgcaaca caaactcata ttgcgacata tcccctgcac
    45721 ctttaagatt cactaaatca gtggcccaag ccaaccataa cggatcttgc ccaaatactt
    45781 gtgtccccgc ctgtgcgcct gataaaatct catacgatcc gccaagctgt gtatagttga
    45841 taggaatcgt cagcatatga tgcaatccaa atggcaatag taaacgttct aatgttccaa
    45901 ataaaaacgg tgctagaatc ggtgcgcttt cttgtgattc tgcaatccat aaaccaaaat
    45961 tattgattcc agcctgtacg tttggccaca ccacagcaag aatcaatgcc acgattgttg
    46021 accataagat aacaacaaac ggaacaaagc gctttccatt gaaaaatgac aaagcatccg
    46081 gcaattttct ataattatag tacttattat aagccattgc cccgacaaat ccagcgatga
    46141 tccctacgaa tactcccata ttcaaagctg gtgcttccaa tacacttgta aaaaatcctt
    46201 taaccatgat cttcgtaccg aacagagtgt gggtaaatgc atcttcattc gcaagcatgt
    46261 cacttgtgac accaaagata gccccagtga tccgattgat taaaataaat gagatcccag
    46321 ctgcaaatgc tccgcctgct ctttcttttg cccaacttcc tcctattgct aaagcaaata
    46381 aaatatgaag attaccaata attgcccaac caatattttc aattactccg cccgttgtga
    46441 caagcggcgt ccaatcagga ttgatcaagg gaattgattt ccctatactg atcatcaacc
    46501 cagctgccgg cataactgct accacaacca ttaaagcctt tccaaatttt tgccaaaact
    46561 caaaactaaa tatctttttc attccgttta gctcctttac gcaatcggtt tcgttaaacg
    46621 tattatagcg tgcgttttct tttttgtaaa tgctttattt tttatttttc tgtctatacc
    46681 attctataaa acctataata cgtgtgttcc cttctataat tttctcctaa aaatttattt
    46741 ttttaagctt ttttctatga aatattttct tttgtctatt gacttgtgca atcggttgcg
    46801 tttattatga acgtataaaa cagctcatta ggaggagaaa aatgaaacag atcaaacgac
    46861 tatttgctat tgatccatgg aaaatcagca cgacacaatt agataaaaaa aatcttcgac
    46921 tgcaagaatc tttaacaagt attggaaacg gttatatggg gatgcgcggg aactttgaag
    46981 aaacttactc aggggaccac catcaaggta cttatttggc gggtgtctgg tatcccgata
    47041 agacacgtgt cggctggtgg aaaaatggtt atccagaata ctttggaaaa gtgatcaacg
    47101 ccttgaactt tatcgcgata gatatttcga tcaacgatca gctgatcgac ttggcttctt
    47161 tggaaccaga agacttttac tgggaattag atatgaaaaa tggtgtatta tctcgtacat
    47221 tcacaatcac tacttctact aataaagtac gcatttcctt cgaacgtttt ctgagcattg
    47281 tcaaaaaaga atcagcttat atctatttaa ctatagaaat gcttgaaggt agcggaacag
    47341 tcaaactcgt atcaaaattg gatggaaatg ttcaaaacga agacagcaac tatgatgaac
    47401 atttttggaa tgagattgat cgtggaacta tagaagaaat cggctatttg acgactaaaa
    47461 ctattccaaa caactttggg attgaacaat ttactgttac tgcagcaatg cgccatttcg
    47521 ttaatggaaa atcagtcatc cctgactatc acgaagatac tttagcatta catggttgct
    47581 tgtctgcaga attatctcaa ggtgagacat ggtcagtgga aaaagaaatt atcgttctta
    47641 ctagtagaga tattccagaa gcgcagcaag cagaaaaagc tgtctcagaa ttaacgaacc
    47701 agacaaacaa ttatatccaa gcaaaagaag agcaaacagc ggcttgggca gaacgatgga
    47761 agcttgccga tgtggtcatc gaaggagacg aagaagcaca acaaggtatt cgattcaatt
    47821 tgttccaact attctctact tactacggcg aagatgaacg attgaatatc ggccccaaag
    47881 gattcacagg agaaaaatac ggcggagcca cttactggga tacagaagcg tatgctgtcc
    47941 ctctttatct tgctttagcc aaacctgaag taactaagaa tctgctgaaa tatcggcata
    48001 atcaactgcc gcaagcaatc cacaacgctc agcaacaagg attaaaaggc gcgctttatc
    48061 ctatggtcac cttcactggt gtcgaatgcc ataacgagtg ggaaatcaca ttcgaggaga
    48121 ttcaccgaaa tggcgcgatt gcctatgcaa tctacaatta tacgaattac accggcgata
    48181 cggaatattt gaaaaatgaa ggactggaag ttttagcaga aatcgcacgc ttctgggcag
    48241 accgtgtcca tttttcaaaa cgagcaaata aatacatgat ccacggtgtg accggcccaa
    48301 acgaatatga gaacaatatc aataacaatt ggtatacaaa tacgatcgca gcttgggtct
    48361 tgcgttacac gcgagaaaat tatttaactt atcaaaaaga agctgctatc actatcagcg
    48421 aagaagaact agccaaatgg aaagatatcg cagagaacat gtacttccca gttgacgaag
    48481 aattaggaat ctttgtccag catgacacat tcttagataa agatctcatg cctgtatccg
    48541 atattcccac aagcgatctt cctctgaatc agcattggtc ttgggacaaa atccttagat
    48601 cttgcttcat caagcaggca gatgtactac aggggattta tttcttcaat gatactttta
    48661 caaaagaaga aaagcaaaaa aactttgatt tctatgaacc aatgactgtc catgagtctt
    48721 ccctttcgcc aagtatccat tcgattttag cagcagaatt aggaatggaa agcaaagctg
    48781 tagaaatgta ccagcgaaca gctcgcttgg atttggataa ttacaataac gacacagaag
    48841 acggcttgca catcacttcc atgactggta gctggttgtc gattgtccaa ggatttgctc
    48901 aaatgaaaac tgcccatgat cagttgagat tcgcaccatt tctgccaaaa acttggaaag
    48961 cttattcttt ccatatcaat tatcgcggac gtttattgtt catctcagtc acagatgaac
    49021 aagttacttt cgagttatta gaaggttctc ctctagaaat ttacgtctat gaacagtctt
    49081 attctttagc ggatcgtcta gaaataacgc taagaaagga ggaagcaaat gtttaaaggg
    49141 gtattgtttg atttagacgg tgtcattacc gatactgctg aattccatta tcgtgcttgg
    49201 cgaaagcttg gtcaggaaat cggcattacg atcgaccaca cattcaacga acagctaaaa
    49261 ggcgtcagcc gagaagactc actctctttg cttttagctt atggcggaaa agaacactct
    49321 ttttcaaagg aagaatttgc agaattagcg aaaagaaaaa acgattatta tttagagatg
    49381 atccagacga tcgaaccaaa agatgtcttc cccggggtcg tgcctttact ggattcttta
    49441 aaagaagaaa aaatcaagat tgctcttgct tctgcaagta aaaacgggcc attcctactt
    49501 gaaaaaatgg gtcttacacc ttactttgat gctattgccg acccggcaga agcaacaaac
    49561 ggaaaacctg cgccagatat cttcctcctt gcagcaaaag ctgtcggact aaaagcagaa
    49621 gaatgtatcg ggatcgaaga cgcgcaagcc ggtatccaag ccatcctctc aagtggcgct
    49681 caaccaattg gcgtgggacg tgctgaagac cttggagagg agatcccgct tgtccctgat
    49741 acgacttttc ttacgatcga ttacttgaaa gaaaagtggc atgaccatgg ataatccaga
    49801 gatctccgtc gtaccagttc cagagactga aataaagaaa atcacattga agaacgacta
    49861 cttagaagtc gttcttctca attacggtgc ccgcctgcac caaatcttcg caccagacaa
    49921 agaaggaaaa tcagaaaatg ttttattgtc ttacgatcgt ttcgaagatg ttctaacaga
    49981 caaaagcttt tttggagcaa ctgtcggacc tgtagccgga aggatccggg atgcttcttg
    50041 gggtgagcat agattggaga aaaactgcgg atcacaccat atccacggtg gcacgaaagg
    50101 ctggtctttc caattttggg aagtagaagt tttcaaaact ccatcatcaa taggtgtggt
    50161 cttttactta aaagatgaat tttctaccta tccaggacca atcactgcta cgatcactta
    50221 ccgtttaaca aaaaacgaat tagagatgac aacctctgct agtagccttg ttgaaaccat
    50281 ctgcaatccg accaaccatg cctacttcaa cctttcagga aatggaacaa gagacatcta
    50341 tgaacatcag ttaacggtct ttttagatgg tgtgcttgaa ttagatcaag aaaaactgcc
    50401 tactggaaat tggacaaaaa aagaaaaact gccaatcgac tttagaaaat ccccaacact
    50461 gcaagagatc cttgcatgtt atccagatgg actagatgat gtatttcttt tgcatcatcc
    50521 taggctttcc aaaacttcct tacaattatt cgagaagcat tctggtcgcc aaatgactat
    50581 agcaacttct aataaaagta tggtattatt ttctacgact ggattcgaag ctgatttctc
    50641 tgtcaatgga aaacagatgc attcaaacta cggattagca atcgaaccgc aagaaatccc
    50701 tgatatcgtt catttcccca aatttggatc gatcaacctc catcctggtc aagaacggat
    50761 cagtcagacg atttatcggt tctctgcaca ataacaagag aaaggtgttt ttatcatggc
    50821 tattaccgta aaagatgtgg cgaaaaaagc cggtgttgcc acctcgaccg tctctcgtgt
    50881 catcaacgat catcctagta tttccgagac aacaaagaag aaagtccgaa aaattatgga
    50941 tgaactaggt tatgttccta acatgactgc ccgcaatcta ggaaaacgca tttccagtgc
    51001 catcggcgta atcttacccc ctcttgattc aaaagagcgg atcggtaacc cattttatct
    51061 tgagatcatg gaagcaatca acgaagaagc gcggaattat gatatgacta cagcaatcgc
    51121 tactgctaaa aattttgaat tgctgttaga gaacgtccag cgtatgcatt tacaaaaaca
    51181 agtagatggt tttattctag tgtattcaga tagtcaagat actgtcattg attatttata
    51241 ccaaaaccac atccctttca ctttgatcgg acagccttat catcatgaga acgaaatcgt
    51301 ttatgtagat aatgataacc agcttctagg taaacaagca acagaatttt tgatccagaa
    51361 tggacataag aatatcctgt ttgtgacaaa cacgactcat gaaagtttgt atttcgaacg
    51421 atatttcggt tatcaaaaag caatgatgat ggctggtctt cctgcgttat ccagtgtagt
    51481 actagagcat ccggaggatt atctgtcctt tgagaaaacg ttgaaagaaa acgaagccac
    51541 agcattggtg gtcattgacg atatcttcgc ccttcgcacg atgcagttgg cgcaaatgta
    51601 tggctatgtc attccagaga cactctccgt cattagcttc aacaactcga tcttctcaac
    51661 attaacacac ccttacctta caagtatcga tatcgatatc tccgaattag gacgtgtcgc
    51721 tatgcaaaag ctgcgcgaat tgatccatga agaattgagc agtggcgtac gtttggtcat
    51781 ccctcatcgc ttgatcaaaa gagagacagt cgttccttta gaaaacccat actaaatagc
    51841 tgactcacta aatacgctga ccatttatcc tatggtcagc tttttatgta aaagaagata
    51901 ctacttctaa cacattgttt atctgtaaaa aagagcgtgg gacaaaagta aagaacactt
    51961 ttgtctcacg ctctaaacac gtataaacgg cggaagcaga agcaactcct tcggaaataa
    52021 gctgaaattc acaaaaattt aaaaagcaat tttcttgagt ttcttcttat ttcttggagt
    52081 taaacgcttc tgtcccagcc tcttttttcc ttccttcaat tttttacacg tcgacgattc
    52141 aataaaaaac cgcctaatat tgtaaagaca ggtgcaagaa tcgagaaaaa ggcgaatggc
    52201 aagtaatgca acgcgctaac tttcatcgtt cccataatga atgtgccgct gactccccac
    52261 ggtacgagag aattgacggt cgcacctgaa tccgctagtg ttcgtgtcaa ataggttttt
    52321 gataagccaa cgtcatcaaa agaacgcttg aatgtttctc ctggaagaat gatggacaga
    52381 tactgttctc caacgatcag attgattccg atacagctca aggcagtaaa cccgactaaa
    52441 cgagaaggtc ggtccatctt ttcttttaat tcttgaacga tggtatcaac gatcagatat
    52501 ttgatcagta acccacctaa tgccaatgca agtaaaatca aactagcaga acctaacata
    52561 ctcatgatcc cgcctcgaga aagcagttca tctagctttg gatcaggtgt atttgcgaca
    52621 taaccattca tcaagatgtc tgctgctttt ccgaccgtca aacttttctc atggataaaa
    52681 gaaagaacga gagcagctgt cgatcccgct agtaatgtag ggatagccgg aatttttttg
    52741 attgcccccc caaataaaat aactagtgga atcaatgtcc aaggagagat ccaaaagctc
    52801 gctttcatgt tttggatcat ttcattgata ctagctagat cggctgaatg actgttatgt
    52861 cctaatatcg tataaaaaat caacgaaagg acgaatgctg ggaaatccgt ataacgcata
    52921 ccagcgatat gttcgaatag attaactcct ccaatacccg ctgccaagtt ggtcgtatct
    52981 gataaaggcg agcagttatt ccctaaaaag gcaccggaaa cgactgcgcc tgtagtcatt
    53041 gcatcattga atccaagtaa atgaccgatc cccaaaaaag caattccaat cgtcgaaatc
    53101 gttgtaaatg aactgccgac agtcactccg acaattgcac aaacaagaaa tgctgtcggt
    53161 aaaaagaaac gcacagaaac aagtttaaat ccataaacca taatcgtagg gatggttcca
    53221 gataaaatcc atgaagcaac taagacacca atcaaaagaa aaatcaggat tggaatgatc
    53281 cctggagtga ttcctttgat gatcccgtca tggatctcat cccatgtgaa ctttttaaat
    53341 ctgccataaa acaacaaaca catgaaagct gcaaggatcg ggatatgtgg cgagagctgg
    53401 aatccgatga tcagtactcc taggagtgcc aacaacacga tcaatacagc gatactttct
    53461 tttaaagaaa tatttttatt catcgtcgat ctcctatttc aaatgaaaag gccctgccat
    53521 gaaaaaacta ttcacttggc aggacctcct actaaatcag cgacaaaacg tcggctgaaa
    53581 gacttatttt tttatttttc ttctaaactt ttttctacct caatccccca agaatctttc
    53641 ttgaagtgat tgatgatcaa tggaataacg aacatgacca ctgtgatagc tgctactaat
    53701 aatgcatcac tcaatgtcgc tgtacctaat gtagcaaata cgacaacgat gatagagaag
    53761 atcagcatgc agctgactac ccaagctaat ccgtttccgt ttttaccaat tcggtaagga
    53821 cgttcgaatt ctggatgttt cttacgcatt ttaagcaatg aaacagcaat caaaatgtac
    53881 acgatacaat aaataacagt tgtagcattt gtaagtgtca agaatacagc acttacgtca
    53941 tccattacac cataaagcaa agcaaataat gaaataacga ttgattgtgt tagaacgaca
    54001 tttctagata cgccgtattt gttttcttta tggaatccga attttggtgg aaggaatcct
    54061 tcacgagcta cttggatgat tgtttttgat ggtccagtaa cccaagctga taattgtaaa
    54121 agcacaccaa taaataccat gaagctgaag atatttccga tcacttctgg taagcctagg
    54181 atttgacagt caatcaagat aggctgcgtg atatttgcta attccatttt tccatctggt
    54241 acgacatttg ctacaagcat cgcattgatg acattcaata aaactaatcc gatcaaagcg
    54301 ataaatacgc cttttgtata attttttgtt gcgtctttca aacgaggcat gtaaacagaa
    54361 ctcatttcga tcccaacaaa aataaatgtg ataccagcta agtatttcaa tgaatcaata
    54421 tgttccaagt cagggaaagc ttttgaccat gaaaagtcac ctagatagcc gtttgagact
    54481 agtccgactt tgaaggctgc caaaacacct aaaacgaaca tgatgactac tgggatatat
    54541 acccctagcc atacaccgat gttcccgccg acttttgcca tatcgaattt caagttcaag
    54601 atcgtgatga tccagtagat aactaaaata caacctaaaa cgaaccagtg attattgcca
    54661 agttctacat taccaaatgt gtttcctaac aatggtccta aagtagaagc gaccattacc
    54721 atacctggga acatttgcac ccataatagc catgcaacga caaatcccca tttgctgccc
    54781 agtgctgttt ttacccataa ctgaggaccg ccttcttgag gaagcatcgt ggaaagctca
    54841 ccggaaacca ttgatatcgg accggcaaaa aacaaaactg caaaaattga ataaaaaatc
    54901 aatgtccaac cgactgcggc taacgtagga atactccgaa ccgttgcaca cagtgccatt
    54961 gtcagaccga taaaggtccc aagacccatt ttacttactt cagatttact caccgttgac
    55021 actctccttg attttttgga taaaataacg gtgtctttga agtagtttca gcaataaacg
    55081 aaacaattca gcgaatattt gaggggattc tttgagttta ttgcttgaag ggtttcttca
    55141 aagacaacct caaaacaaag ggatcgaaga gcttaggtct ccccttgctc ttcagatcca
    55201 aacatgcgtc agaaacagtt agtattcaag ctgttttcta acatgattac cttgcttatt
    55261 ttgcttcgct tgccaataat tggtctgcgt agattttttc caatttttct tgaagagctg
    55321 ctttgatttt ttcagcatat tcttcaaagt gttcttcttt gttcatgtat ggtgtcatta
    55381 cgctggcacg caatacagtt acttttccgg cacggttcca ttcttcatct gagaatccta
    55441 gttggttcac aaattgtaat gggctgttgc catagtctgg gatagcaaag tcagtatgtg
    55501 aagttaagaa ctcattaccg taaatgcttc ctttcacgta tgaagaataa tcatatacgt
    55561 catggttcaa tttattcatt gcaactaagt catcgttgcc tttttctttg aatacatagt
    55621 ctaccatatt gaaatctgga taagttaatg gatgaacttc gatttctttg tctcctactt
    55681 taaatgacaa gtcattcaag aagttgtaga aacgatgtgc accttcgatt gatgcaccca
    55741 ttaatttacc atatcctgtg acattcaaag gtaagacatg gtgtgctgcc caaacgctgg
    55801 ctgctgttgc ccctgctttt gaaccttcca agatataagc cccaagtaat gctgggatat
    55861 ctgcgccttt ttcaaataca tatgtcgcaa agtaagagat aacgtctctc atgcggatat
    55921 ctttgatgac gataccaccg gcagaatatg gaacatagcc cattttatgt gggtcaatcg
    55981 ttacagattc tgcttcttcg attgctttat atgcactgtg tacttcttct aagatataat
    56041 ctttgttttc tgtaaagaca ttgtatttgt aatgaacatc ttttaaatct tcaaatggaa
    56101 tgaagttgtt gtcttcgtct aagaaaatcg cacggccgta tccgccataa gcagcatcta
    56161 cgtgtaagta gaagtaaata ccgtcttttt ctaatacgcg acgcaatgca acgattttat
    56221 cgataccgtc gattgctcct tcttctgttg atcctacaac accgactaca cctaggattg
    56281 gtgttttttc agctgctaga ccacgaacga ttttttcaag ttcgttgatg tccatgcgat
    56341 agttgtggtc aactggcact ggaatcactt ggtctaaacc gataccgatg atgtcggcag
    56401 cttttagcca tgaatagtgt ttagtttgtg gaaccaacca ttttcctaat ttttctaaat
    56461 gttttccgct acgtgctgag tgagctttga tttcgtcgat tttttctggg acgctgtcta
    56521 acagattcat gatttcttct gttgacaagt tcattaattc ccaatcgctt tttccagcaa
    56581 ctagttcagg tgtcacttct ttcattgcaa gcggcaatga tttgatgttg cgggcatacc
    56641 aaagtccttc taagtttgct aaagaaccat cagcaacgat gtggccccag ccatctttat
    56701 agctcattaa ttttgcaaat tccattccta cttcttcttc catttggctt gttgcaggag
    56761 aagattcata ggcaacgtta ttaccattcc atagcatagc aaaattgtac gctagtaaag
    56821 atggcatcaa tgtttcagag ttcatatgac cccagtaacg tccggcatta tgccaaggaa
    56881 cggaatgggt acgcatccgc gctgaaattt ctgatagaac atcctttgtt ttattcacag
    56941 tgtgttcaaa actagcactg cttttttctt ctggcgtaat aataggcatg tcttgaggca
    57001 tgtagttttg acgccagcct aaatgttcat ccaccaattc attcaacaaa gctttataga
    57061 tttggccgtt ctcagctttg tccccaatga atagggcatt taggtttaga tctttcgaca
    57121 atgattcact catagtgaaa ccctcctaaa aaaatattta aattttgtcg agccctacat
    57181 tacacctgtt cttctattct gtaaactaag ttttggcctg atttttaatc atattttaat
    57241 atgtatcaat tatccgaatt gttcacactt ttgaaataat taaaaaaaac gagggaattt
    57301 acaaatgtaa actccctcgc aaagattgta ttaacgacaa ccagcgttct attttaggat
    57361 gggtttcaaa attggaatgt tgtaatagta tttccctttt tcaaggtaaa aacttactaa
    57421 attctaatca attactttgg ccaaaaagta atttttctta ccttttcgaa taaccacaaa
    57481 cttaccatcg aattcatcgg atggatttat gacaaaattt aaatcggtaa cgcggtcacc
    57541 gttaatactt atagctccgt ttgaaacatc ttcacgtgct tgacgtttag atggttcaat
    57601 ttttgtggaa acaagcagtt ccacgatatt ttcaggtgtg cttgaaattt caacgttcgg
    57661 cattttaccg aatccttgcg cgatttcttc cgcatttagt tctttaatat ttccagagaa
    57721 caatgcttgc gttatttttt gcgcttcttt caagtcttct tcactatgca caaatcttgt
    57781 aacttcttct gccaaacggc gttgtgcttc acgtttctca ggttctgtct ctactttttt
    57841 cgctaagtct tcgatttctt cttgagacaa gaaagtaaag aatttcaagt atttcactac
    57901 atcgcgatca tcttgattca accagaattg gtagaactca aatggtgaag ttttcttcgg
    57961 atcaagccaa acggcaccgc ctgcagtttt tccgaatttc gttccgtcag ccttcagcat
    58021 caatgggatc gttaaaccga acgcttctgc ttctggtcct tctaattttc ggattaggtc
    58081 taatccagct gtgatatttc cccattggtc tgctccaccg atttgcaatt gcacatcgta
    58141 tgttttatgc agatgcaaaa agtcgataga ttgcaggatt tggtaagtaa actctgtaaa
    58201 tgagattcct acttccaaac ggctggcaac gatatctttt gctaacatcg tgttgatgtt
    58261 gaagttttta ccgtagtctc tcaaaaattc aagtaaagag atttttgaca accagtcgta
    58321 gttgttcaca aatgtgatat ttgcatcttt accaaacaat tttctcattt gattggaaag
    58381 tgcgtccacg ttatgttgca cttgttccat cgtttgcaac acacgttctg ttttgcggcc
    58441 gcttgggtcg ccgatcgttc ctgttccgcc gccaatcaga atatatggat gatggcctgc
    58501 caattggaat cttttcatca tcataaatgg aatcaaatgt ccgatatgca tcgaatcacc
    58561 agttggatca acgccgcaat aaagtgaaat gctcttttct tcaacgagct cgcgaagtct
    58621 ttcttcgttt gtttgctgat taatggcgtc gcgccaagtt aattcatcaa taatattcat
    58681 tttactgacc tccgtgtagt ttttttatga aagcaggaac ctgctagcat atgtaattaa
    58741 ttatttcttc aggataggat aggataggaa ataaaaaaag tcccttggca tataagccaa
    58801 gggacgaaat ctcgcggtac cacccaattt gtatgtctag atatccaaca tacctctcga
    58861 acatttaacg ctgtcgcgtg gcaatcactg ccaaagactc ctgaaatgta attcgcttta
    58921 aagcatgtac tggtttgcag cgaccaccag ctttctgaaa cattggcttt aacaactact
    58981 tcgtttcgat cttcgtcttg ttattattaa tatgtgtcta tcatagagcg caactttttc
    59041 tttgtcaaca gaaaaaggat atttttttta aattcctcat tttttctttt ttgaatccgc
    59101 tctaattccg aacattttat tttcaattat tgttaaaaga aataactttt tctgtatttt
    59161 ttctgcaatt tatcgagaag tcactttact ttgcctctta ttctttcttc gttacaataa
    59221 ggaatgggac aagtaaaaaa atgaaaaagc aagggacgag gtatatggaa aaaaagcaaa
    59281 aaattatttt aggagccact tctgctttaa ctatcgttat tttaattcta agtttgtttt
    59341 ttgtcatccg atcatctaca aaaaaagaac caatcattcc tgaaaaaaaa ataacagaaa
    59401 aagcaaaaga accgacagat gataagcaac aactagttac tcaagcaaaa aatctggctc
    59461 aaagctacga ttatgaccaa gcgattgcgt tattggaaaa agatagtaag aacggatcta
    59521 ctgaaacaca acagcttctt caaacactaa aaaaggagaa agaacaactg atcgactggt
    59581 ctgatcctac tcagatctct catgtctttt tccacagctt gatcgtggac ccgcaaaaag
    59641 ccttccactc tcaacaggca caaggataca aagattatat ggtgactgtt gaagaattca
    59701 accgttcgat cgaacaactt tatcaaaatg attttgtttt agttaatttg aatgatttga
    59761 tccaaaaaga cgaacaagga aatctttcct ttaacgggct tgcgctacct gaaggaaaaa
    59821 aaccattggt tctttcacaa gatgatgtca gctattatga atatatggat aattccggtt
    59881 ttcctagccg attggtcgta tcaaataaca atgaaatcaa aaatgtctat aaagagaaag
    59941 ataaagaaga aatcggtgac tttgacatgg ttcctctgat cgatgccttt gtcaagaaac
    60001 atcctgattt ttcttatcga ggcgcaaaag gtaccttggc cctgacaggt tacaacggag
    60061 ttttaggtta tcgaacatca aaatctcaat atggagacaa tgaaaaaaca aaaaaagaga
    60121 ttaaagaagc taaaaaagtg gcggaacagt tgaagaaaga cggctggagc tttgcttccc
    60181 atacatgggg tcacttgaat atgactcaag cttcactaga agatgtaaaa aaagacaatg
    60241 aattgtggca gcaagaagtt gcacctatcc taggaaaaac aaatattctg atttatccat
    60301 ttggtgcaga catcagcgac tggcagcctt attcagcaga aaatcaaaaa tttgcttact
    60361 tgaagagtca aggtttcgat attttctgta atgtcgatgc ttctacacca gcttggggac
    60421 aattaggtac ggatttctat cgaaatgctc ggatcaatat cgatggcatt cgttttcaat
    60481 ctgatttaga cggaaaaaat cctattcttg atccattcat caatgtccat gatgtctatg
    60541 acaaagaagc acgcgaatct gcttgatttt acgtcattta tgaaccaaaa aagccgaact
    60601 gacattttat cgtcagtttc ggctttttta tgctttattt cttcttcggt gcgattccct
    60661 tgatcaggac ttctgtccat tctgctgtat atggaagcag ttttgcgtat atctccggct
    60721 tagaaattcc ttctaccatt gcttgaaaat agaggatcaa gaactcatcc gaatatttca
    60781 aatccacttt tccttctttc cgccctcgat ggaaaagatc aagcatgata ctgaaacttt
    60841 cttgcgtata cgcatccatc gcgtcagaaa attctttttt ttcttttttt gtatagtatg
    60901 tcatcaaatc gatataaaat tgtttgttca ctcgattgag ataacggatt ttgttttcac
    60961 tcatggcaat cagtgtttct tcaaatggaa gattttccgc aatcaacgct ttcgcttctt
    61021 gccctaaatc attcataaat gcaaaaaata cttcataaat cagcccttcc ttgctgccaa
    61081 aatatttaaa aatcgtcgct ttacttacct gagcgttctc agctacctta tccattgtca
    61141 ctccagcggt tcctatgtct gtgttcatca agtcaaaagc tgcttgtaaa atctctttct
    61201 ttttctcttg tgctctcttt tcaaaaccgt tcatttgtag agcctcccgt aattttaaac
    61261 ttttataata tatatagttc aaatttattc tgaggtttat tataactatc tattgagaaa
    61321 gtatcaagct agcaattcct tgtttatgaa ttcattgaca gaaatttata aaaagaatat
    61381 tatgtactaa aataataaaa aaagttttat aaaaaggtat aaaacctttt tattaaacta
    61441 tttaatcttg tttagtatat atttttagaa aaaggagtgg ggtttttatg gcagaaatcg
    61501 tcaaagtcac acatttgaaa aagagctttg gtcgtttcga agctttaaaa gatgtctctt
    61561 tcaccgtaca ttcaggtgaa gtcgttggat ttatcggacc aaatggttct ggaaaatcca
    61621 cgacgattcg gacactttta gggattataa aaaaagacgg cggaacggca acgatttttg
    61681 ggcaagatgt atgggaagat agtttatcta tccatgaacg tctttcttat gttccaggcg
    61741 atatctcttt gtggggaaat ttgactggag gagcgatcat cgatctcttc atgaagcttc
    61801 atggaaaagg gagtgctcaa aaaaaagatg aactgattca acgtttctct cttgatccta
    61861 agaaaaaagc aaaaaactat tcaaaaggaa atcgccaaaa agtgggcttg attgctgctt
    61921 tggctgttga ttcggatctc tatttatttg atgagcctac ttctggttta gatcctttga
    61981 tggaaacgat tttccaagaa gaagttgaaa aattgaaaga acagggcaaa tccatcctac
    62041 tttcttctca tattctcagt gaagtcgagc gactagcgga taaagtcgtg atcatacgcg
    62101 aaggaacact cgatgaagaa ggaacactcg atgaattgcg tcatttgact cgttcgacca
    62161 tcactataga aacagaagca gagaatagtc acttagcaca attgaacggt gtccatgact
    62221 ttgtgcaaaa aggtcacctc gctcaatttg ctgctgataa cgaagctttc gatgtgattt
    62281 tagctgaagc gtccaaatta ggtgtgaaaa aatttgaatc tattccaccg actcttgagg
    62341 atttattcat gagacattat gaaggatgag gaggaagcga aatgactgat aaattttcac
    62401 gctggtccac ccttttttct caaaacctta gccgtgactg gaaaaagatc ctgatatggc
    62461 tagtcggtgt cactgctttt tctggtggtt ttgtccctgc gtttgaagaa ttgacttccg
    62521 gacaaggatt agctggatta tacgaaacct tgcaaaaccc ggcaatgatt gcaatggtcg
    62581 gaccaactcc agcttcgaat gctgctgagt atactttagg agcgatgtat gcaaatgaaa
    62641 tgttgctttt ttgcagtttg tttgctgctg tgatctctgt tttacacgtg gtgagccaaa
    62701 cgagaaaaaa agaagaactt ggtctgattg aacttattcg ttcctttcga gtcggacgtc
    62761 aagcaaactc tttagctgtc atcgctgaaa gtattctgat caatttgctt ttagcaatat
    62821 cgatcagctg tacgatgatt tttttccaag cggattcgat cactgcagaa ggtgcttggc
    62881 tttttgggct atctgtaggt agtatgggga ttttggggag tgccgttgca ctgtttgctg
    62941 cacaactgat gccaagttca gccagttcga atggtctgtc tttagcgttt ttaggtggac
    63001 tttaccttct acgagcaata acagatgtag ctgattcctc cctttcgatg tggaatcctt
    63061 taggctggtc ttatttgacc tatccattta caactaacaa ctggattcct ttgctttatt
    63121 tgtttttgtt cagtctaatc ttgataatca gttcatttgt tttagaggaa catcgagatt
    63181 tgaacaccgg ctatatcccc gaacgtgaag gaaaaccgta tgctaaacgt tctcttttat
    63241 ccttgcgtgg tttattattc tatctaaata aagggatgac aatcagttgg cttatcactt
    63301 ttggtttgat gggggcggca tacggctcta tctacgggaa tatgcaacag tttttagaaa
    63361 gtaacgactt aatgaaacag atgtttatcc aatctggcgt ctcaattgaa aaaaacttta
    63421 caagcacgat catggtagtc ttgatttgtc tagctgctat tttaccaatt gctagcatca
    63481 atcgtttatt tacagaagaa acccacggac gtatgaatca gctgttcgca acaaaaattt
    63541 ctaggaacca actttattgg accaatatgt tactagctat tctatttgct atattggcaa
    63601 tcctgattag ttctggtgca ctagggcttt ctgctttggc ttcgatgaag gatgcgaaag
    63661 acatggatct attgatgttt cttaaagccg ggttcaattt cctgcctgcc gttttagtgt
    63721 ttatcggaat tagtggcttt ctattcggat ggcttcctcg aatcggtaaa cttgcttata
    63781 tctacttagc ttactccttt gcactcaatt actttggcgg aattttggat ttaccagaat
    63841 ggttttccaa aacagctgtc cctagctggg ttccacggat gccaaacgat tcttttgatc
    63901 tttccgtgtt ccttacgtta tcatgtatca gccttgcact gttcgtcctt ggttctattg
    63961 gttataggcg aagagactta ctagaaggat aataaaaaag catgtacaat ttcatgctag
    64021 cctccaaatc tgggtcaaaa atccaacatt tggaggtcat ttttttattt acaagtcttc
    64081 taactgctct ttatcaatga tccagacttc tcgattcttt ctttttacat aaccattctc
    64141 ctctaataat ttaaattttc tagataaagt ttcgggggtc gtaccgataa atgcagcaag
    64201 ttctttcatt ttcattggca ggaaaaagtg atccttccct gtcgctttag ctaagtcaag
    64261 cagatagaca gcgactcgtt cttctacttt ttccatcatc aaaaaagttg tctgctgctg
    64321 tacttttgtt aatttctcaa cgttgattgc taaaagtttc agactaaggg cgggataatg
    64381 cagtaagagt tccgagaaat ctttttgtct caatatgcaa atttccgttt tttctagtgc
    64441 ttcgccaaat aaagactcat ttggaacgcc tagcaactgg ctctctccct catatccgcc
    64501 cggctctatt actcgtaaaa gctgttcctt tccgctagca gataattgat acactttcat
    64561 actgccggag gccacgatca ctaattgagg ttctccattc ggcgcaagaa tctgttctcc
    64621 tttttccaca tagtgatgtt tgacaagtgc gtgtactttt tcttgatctt gctgtactaa
    64681 gtgattgaac aaaggaacaa atgaaacaca taaatgatca tgactcataa tctctcctcc
    64741 ttctaaacag ctatttctaa taaagaaaca taacttccct tattccaact gataattttc
    64801 ttttatcata gcataaacgt caagcgaacc agataccagc aaatagagtg gatttctttt
    64861 tgtcccttgc tttattttcc ttcttttgag accttaagta attgattcct atcaattttt
    64921 taaatattta ctttttgaat aatcaaaaac aaaccttcac tcgcaagccg agagtaaggt
    64981 ttgtttttcg cattgcttat ttcgtgttgt ctattgaaat ttttccgcac ctagcttttg
    65041 atatagtggt gctagttctt gtaaggtttc agcggttatt tgctcaacgt gttcgatttc
    65101 ttgcggatag aagaatagtt tacccatttg aaaggttcgg tctctcatcg cttttttcaa
    65161 ctcttcttgt ttctttgtat cggacaaata gtcagacaaa gctaagtggt cgtcaagttc
    65221 atgttctggt tgcggccata tgtaataatc cttgatatcg actgttttgc tccactcttt
    65281 cagtatcgca agcaactggt tatacgctgc aatgctacca tatcgttctt cgcttttata
    65341 atgttggtac atcaaataga tttggtattg tttttgattc aacaaaactg ctagacaggc
    65401 attctcgtct tgacgagatt cgcttcggta cgcgctccaa aaatgactgc gtaaattcca
    65461 gccattcgtc cagctttcga ttttaggttt gctcatgccg tacatatcag gcaaaagtgc
    65521 agctgtctgg agctgaatct ctttccattt ttgccagtgt tctttatatt ctttcttgat
    65581 ttgttcaatc ttatctgttg gatggctctc tttgagctgt ttgaatgcgt agattggtcg
    65641 atcaaacaac tgataatctg attttccaag ttccattgtt tcgcctcttt ccgttatctt
    65701 ttgtattcta cctgaatttt gcgatatgga caaatagagg ttgtgaaaaa gctgttctgc
    65761 atcaagtcat aagaacagcc aaacaaaaaa ctgcgatgag catcaccgca gttttattga
    65821 acttaaggtt gattgatcac atctaaaagc gttgaaaata aaatggcact agaagcagct
    65881 cctgggtcga tatgtccgat tgcacgctct cctagatagg aagctcgtcc ttttttagct
    65941 accaagactt tggtgtgttc ttttgcctgg tcaatgattt cttttgttaa attccctgcc
    66001 ttcaatgcct ctgtgactgg cagccaaaca tctaacatcg ttttatcgtc agcttctgcc
    66061 tttcctcggc tttgaatacc cgctgttccc tgctcgatca cttcgcctaa tttttcttga
    66121 gaatcaatag aatcgacctc ttttgtcgct ttcatcatgt tcatgaatgc agatccgtat
    66181 aacggaccag aagccccacc gactttcgat atcatcgcca tagagaatac tttgaatgta
    66241 tcgctgattg tttcaggatg atcggcttga aaagcttctt cataagctga aacccctctt
    66301 cccatgttat ttccatggtc tccatcgcca atcggggtat ctagatcact gagatattgt
    66361 ttgttctgat tgattgcctc tgcaaattgc gtgagccatt cttggatttc ttgaacggtt
    66421 agtttcatat tatcaccctt ttatcttgag attttttacc atgaaatcgt ctgtacattg
    66481 ctttctaaag aatctttcca ttgtgtctcc gtcaagtcga tcagtgttag agaaagacct
    66541 tgcatatcta gtgaggtcat aaaattaccg acttttcgga aaactacatt gacgcctctt
    66601 tcttccaaca gagctaaaac atcattcatg aacacgaact gttccatcaa aggcgtcccg
    66661 cccattccgt tgactagtac acctgcttct tttggtaaat tcgagtaatc atctaaaatc
    66721 ttagtaacaa gttcctttgc cagtacttta gaaggctgca tcttttctcg acgatagcct
    66781 ggctcaccgt ggataccaac accatactcg atctcatctt ctcctagttc gaatcctggt
    66841 ttccctactt ctggtacagt tgctgctcga agcgctagac cgatcgtctt agttgcctgt
    66901 acgacctttt ctcccagttc tttcaactca gctagggaag caccgtttct tgctgcatcg
    66961 cccacgattt tgtgtacaag gacagtacct gcaactccgc gttttccagc agtatacgta
    67021 ctattttcaa cggcgatatc atcatctacg atcacacttt ctacttcaat atcgtccata
    67081 gcagctaatt cctttgccat atcgaagttc aatgcatccc ctgtataatt cttaacgatc
    67141 agcaaaactc cttttccact atcggcttcc ttaatagccg tctgaatctg atctggagtt
    67201 ggagaagtaa acacatcacc aagcaccgct gcacttaaca tcccttcccc tacaaacccg
    67261 gcatgggatg gttcatgtcc gcttcctcca ccagaaacca aaccaacttg ttccgctttc
    67321 tgattcttgg ctacaacacg ggaagattct acacgatgaa caagttctgg atagcttttt
    67381 actaatcctt ccagcatttc ttcgacaata ttgcttggat cattcatgat ttttttcaat
    67441 ttattcccat cctttctttc cggcattttg tgcttctgtt aagatttgct gagtatcatc
    67501 tgttataccg gcagtgatgg ctgctgcaaa agctccttcc actaaaggcg catccaccag
    67561 atgataacgt tgctgctgct cttcttccaa catgtctttt gccagttccg agttcaatac
    67621 cgcgctaccg atatccgcaa aaacaaaata actagctgca tcgcttgatt cattgactgc
    67681 ttctacgatt ttcatcgggt ctgatccgat ctcgccattt attccgccga gagaaaaaat
    67741 ttgcacctct tcggattttt gcatctgctc aatcatttct ttaataccat ctgttacttt
    67801 ttgactatga gaaataagca aaatactttt tttcacaaga atcttccttt cttttacata
    67861 gttgctaacg attggtttcg ctttcattaa tgaacaattc aagtatataa taaatttcta
    67921 attttgggaa aatatgtgta gtgcttcttg aagtttgtta tactttaatt aaaagagagg
    67981 agtgatcgaa tgattacaac aacaacgaac agtgtagagg gaaaagccgt agtagcttat
    68041 aaagggatcg tttttggtga ggtcattact gggatccatg catttaaaga cttggaggcg
    68101 gggttgcgaa atatctttgg cggccgctca aaaagctatg aaaacgaact aatgggtgca
    68161 agagaagaag cacttgccga aatggccgaa cgtgcaaaag cattaggagc tgatgcgatc
    68221 attggcgtaa aaatggacta tgaagtatta ggcagcgaca atggcatgct gatggtcaca
    68281 tgtagtggaa cagctgtctc cacgagataa gtaggggaca tctgttttaa taactaaaga
    68341 gagatgggac atgtagtggc actcaagaat tagatttttc agtctaactt cgaggtactc
    68401 taccttccca tcctctcttt tttatttctt tttgcggatg attccgtaag ctgctgcgac
    68461 taacacaccc gcccctgcta aggaataact gacagaagct gttttttcat ttgtttttgg
    68521 caaagtctga cttgttgatt tggatggctc tgtcgtttgc tgaactgttt ctgtcgtgct
    68581 tccagaggtc actgattttt ctcctgccga atgcaaaata tcttttattc gttggaaact
    68641 agctgctaag tcagcttttt ttgcttcaaa atcattagca actgtttgtg cttcgctgat
    68701 ctttccgtgg attgcttgac tggccgctgt gatatccgct tgagtttgac ttagctttcc
    68761 agaagctgtt tgagcaacct gatttaattg ctgattgaat tcttttgctt gttggatctt
    68821 cccgtcaaga tctgtttgga cagcttccgc ttttgctttc gcttcggcaa gctttttctc
    68881 aagttgtgca cggtcatttc ccactttatt tttaagatca gctaaatctt gatcgattgc
    68941 tgcttggtct tctttcaatt tgttttttgc agcttctaat gcttcttcga gttcttttct
    69001 tttattttcc aagtcttgca aatgatcgat ttggtcagaa gaggtagaac tatttattga
    69061 tgtatcttct gaagatgaaa tcgtttctcc tgaattatct gtcggtacat tggaagtcat
    69121 ttctgtttcc gaggcaccgt tttcagcacc agaagagctt atggttgttg aaggttctgt
    69181 ttgagcaggt tcagaagttt ccgcaaaagc tgtctgtccc aataagaaaa tactggaaac
    69241 agcaattggc cagattaacg gcttcattct ttttttcatc acttttccca tccttactac
    69301 tttttaacta atttcttatt ataagcaaaa atgtttggaa gaaccataaa cacaacaggc
    69361 tgtttgtcta aaaaacggtg catcttttat ttttttgtac gttccgggct tttccatgtc
    69421 ccgcttccat aacctaaaat cgttttgact gctggaatga aagtcgtcac gatcgttatc
    69481 gcgttcacta tccagaacaa aagcatatat agtggtgcga aaagaaggta tttcaatttt
    69541 cttcgtcgat catctacaat cagcgaagct agcaactgga aaaatcctgc gaccatttca
    69601 aagcagatga acacaaaact gaatgtaaaa gtaatataaa tctgttcgta gtttccttga
    69661 tatacataat gcccgattaa tccagcaaaa agaactacgg aaatacaaaa gaatattgac
    69721 cagacaatac tcaatgtttg atcaatgaag atgatcgttc ttccaatatg tttaaaagga
    69781 tggagcatca cttttttgaa attcgtcagc cagacttctg ttccaccttt tgcccaacgt
    69841 tttctgtgtc gatatagcat cttcaacgtc acaggtactt ccatgaaaaa gataatctca
    69901 ggagcaaaaa cagataacca gtcatttaac tgatgatccc aagcaatact gatgtcttct
    69961 gtcgctcgat cttgtctgaa tccgcccaca tcgatcaagg cttcttttcg atacatcgta
    70021 tttgctccac tgtacgcata aagaccaccg aaaacagctg actgtgttcg tttaatgatg
    70081 cccacgatac ttgagaattc aaccgtttga gattttgcaa tcaatttggt acgattttgg
    70141 acatccatat ttgcagtgac cgcagcaata tgtcttgcac cagggcgaat gaaataattc
    70201 acatacctaa tcagtgcatc tggctccggt accgtgtctg catcattgct taaaatcaat
    70261 ttcccttttg caaaggcaag tccgatatta aacgcgtggg cttttccttt atttttttcg
    70321 atccgaacca cacgaagatt agcgtatttt ttcatcagtc tagctaatat ttctggtgtt
    70381 tggtccgttg aaccatcgtc tgtcactaat acctcatagt tgtgataatt caatttcgtc
    70441 atcaaatact cgattgtata ttcgatcaca atttcttcat tatgggctgg caccatgatc
    70501 gtgatgaacg gttcgacact caagggaaca tctacccatt ctttttgctt atgtttgtat
    70561 aaaaacacat aacaccagac accaataaac gatacaaatc cgcctaaaat cggataagaa
    70621 acgagaaaaa aatacataat agacaaacaa gtatctaaga ataaattacc tgtatgggtg
    70681 attgagatca tttcagttcc accccatttt ctttatacaa atctgcaatg aatgtcgtat
    70741 ctagattttt ctcttcggag acagaataaa aacggaccgt ttctctctct tcttttgttc
    70801 caaaacgttc cgtatacact tcttcaagta attcttgtct ttttttcaat ttttcatctt
    70861 catattcaaa agatttattt acttttttgt atagatttcg attgttccac ctagtcaata
    70921 caaatgaggt aatcaggaaa ctgaaaaaaa tcaatacaaa aaagccgatt aagaaataca
    70981 gcattttctt ttctgataaa aaagcgtaca aggaaaaatc cttggctctt tctggtctcg
    71041 ttaatgggaa aaagacccat ataaaaggaa gaacaacgat catccatcct aaaagagcca
    71101 ctaacgtttg ccaaatcttt aaccagtaat taccttttga aaaatactta tctttcacca
    71161 aaattgatgc aacttcttct cttgttactt ttttcatatc ctcacctcac gtttttttgt
    71221 tacgacgtag gagtttacca tacatttcat ttcttttcac ataaagtgtt cctaaatttt
    71281 tcctaagaaa aagaacaaaa catttctcat cagcaaatga aaaatatttt gttcttttta
    71341 tcagttgttc tttttatttt ttatctctta attatgttgc tctttccaat acgacaatgc
    71401 ttttcattcc tctagatatc gccgtgtaca tttgtctgcg tcttctttgc tcatctccat
    71461 cgttttcaaa tggatataag attacatgat caaattccag tccttttgct agactcaaag
    71521 gaatgatttg gcagttttct aatccatatg aatttttttt aatcgattct tgtagcgttt
    71581 gggtttcctc ttctgtttgg gtgataactg ccgctttttc tccttttaga gaaaccaaaa
    71641 tctcagctag tattttcaac aattcttcag aggatcgaaa agagcggtat tcgggttctt
    71701 ttccttgcgg tcggatcgat acgatgtcga tcttctcttg atccacagca taggttttga
    71761 aaagctctgt gattgctccg ctagaacggt aactatttct aagatcatac cgatggatcg
    71821 gcagatggta gtcgtcgaaa caacgcataa tatcagcaaa agtagtggaa gaattaaaga
    71881 ttgcctgatt ctcgtcacct actaaagtaa agtgagtttt tggaaataat tcgatcaata
    71941 gacctaattg tgccagggta taatcttgta cttcatcaat caatagatag cgaaatgctg
    72001 gtacatttac cttttcaaca agtaaatgac gaatagctaa tataatgact gcttcatcaa
    72061 cagtacgtgt gggttgccaa gcataagctg agccatatcg tttttcataa attctttcaa
    72121 acaactgatg ctcatccacc catgccattt cttcgatttg tctggttatt tttcgatatt
    72181 ttttttgtaa aagtttcctt gcataagcta caatactttg ttccgaatca tcagaaatca
    72241 atttaccgaa taattccaac tgcctatctt ctgtcaacga gagtacctga ttctgcacag
    72301 caggactttt tgcttgtttc aaaagatgat tcttccattc gctcatcagt gcctttttcg
    72361 ttgcttgaag cctatcgatc aatttaggat gagcaggaac tttctcatat attttttcga
    72421 tcgttttttt agaaaggact gtttttccat ttttagtaag tccacggata aaattcggat
    72481 gatctaaaaa caaaggatct gattgtttta gattatcgat aaactttttg ctacgcaaac
    72541 gttctgtctg ctccgataca ttttctcccg tgatacgttt gaaataagcc tcttcacctt
    72601 ctatttcctc tgctgaaagc tgtgaaacca gctgtatgat ggttagattc agtggatttc
    72661 tttcacctaa tgatggtagg acattcgaaa tatagtcgat aaaccgatga ttaggtgata
    72721 gaatcagcaa gtcatcggat gtcatcgtat ctcgatataa atagagcaga tacgcaatac
    72781 gctgcatgat agcagaggtt ttaccacttc ctgctacgcc atttaccaag atattttgac
    72841 ttttcacatc ccgaatgatt gtgttttgtt ccgattggat cgtagcagtg atagccttca
    72901 tttcattggt ctcatcttgg cctaagactt ctaataatac gtcatcttga atagctacag
    72961 acgtatcaaa aaacttgacc aaacgatctc tttccaaaag aaattgtcgt ctttctttaa
    73021 taaccgtatc gattttattt tgacgaaccg tataagaaga tggaccaatc atgttattgt
    73081 aaaaaagttc ggcaattggt gaacgccaat cataaacaag attttcatct gcatcatctg
    73141 tgaaatttgc tgtaccgata taaaaggatt cttttggctc attatccaga aagtctacaa
    73201 cgacttttcc aaagtaggga cttttcaata aacgttcgat ctttgctagc tgattttctg
    73261 cgtttttctg tttgatattc atctgatcga tttctctatt tttcatttca atcatcgaaa
    73321 aagtatccag gttatctaag taactgtcaa aattcaatcg aagctcgcca gccatttctt
    73381 tcaacgactg gtttccttct atttttgccg tatccatcga ttcccgcagt tcgttttttt
    73441 tatcaattag cttttgatac acgttcttca gatatgcttc ttctaactgt ttttgtgtgt
    73501 tgaccataca cattctcctc tttttttaaa gtggtggaac cgattagttt acctctttta
    73561 agagtcgaat gcaagctttt taacgagtat catttgttag gatatatcag ttcttcaggt
    73621 cggacagttt gatataaaga aaatgcacca tcaaggtttt ttacgtggta gccagactgc
    73681 ttcaagattc tttccgctag atagctacgt aatccgctat gacagctgac gatatattct
    73741 tgttggctgt ctaattcatt taatcggtcc cgaagttcat tcaaagggat atgtttggct
    73801 tccttgaatt tgcccttttc caattcttct gctgttcgca catctaataa aatttttcct
    73861 tttgctagtt ctgtcggcaa ttcatgccat tgtacggttt cactaagccc ttctgcaatg
    73921 ttcattgctg catatcctag catgtttact ggatctttgg ctgagccaaa tggcggtgca
    73981 tacgtcaatt ctaattccgg taaatcgaag atcgtcaaat gccctttgat tgctgttgct
    74041 aaaatatcga tccgtttatc cacacctttt gccccaacac cttgtgcacc ataaatctcg
    74101 ccagtctctg gatggaagat caacttcagt aaaatatctg ttgcttctgg ataatagctt
    74161 gcatgatctt ttcctgatac atgaatgact tcaaaagaca gttcgttttc tttggctgtt
    74221 ctttcactta aaccggtgga tgcggcagtc attccaaacg ttcgtataat tgctgttcca
    74281 ataccgcctt gatttcttcg agaaattccg gaaatcgtgt ccgcaacttg tctaccttga
    74341 cgattggctg gtgaagcaag agaaataagt gcatcttttc cagtgatttg ctgttttaca
    74401 acgatagcat cccccaccgc ataaatatca ggaatattcg tttgataacg ttcgtctact
    74461 aggatacccc cgcgtatgcc taattcgatt ccagcggtca ctgctagctg gttatcagga
    74521 cgaacaccaa tggataaaat aactaaatca gcagggatgg tacgcccatc atccagtcgc
    74581 aatcgtttcc cgtggtcttc aaatccagcg acagcatgag aagtaatcac ttctactcct
    74641 tgatgagaca attctttttc tataaaagct gccatttctt catccagtgt tggaagaata
    74701 tgtggtgctt gttcgatcac catgacttct aaacctcttc tttttaggtt ttctgccatt
    74761 tccaatccga tgaatcctgc accaacgatc acggcacgct ttggctgttt ttctaatgca
    74821 tgcatcactt tatcgatatc tggtacattt ctaatagaaa aaacattgtc ggcttctgtt
    74881 atccctggaa tcgatggaac aactggtttt gcaccaggag ataaaaccaa tgcatcgtac
    74941 tgttcaatgt gtttttgacc ctcatgtacg acttctaccg ttttgttttc gggaaagatg
    75001 gctgtcactt catgatttgg acgcacatct aaacaaaaac gagcggataa tgattctggc
    75061 gtttggacaa gaagattttc ccgttcactg atttctcccg aaagataata aggcaagccg
    75121 caatttgcaa aagaaacata cggtcctttt tcaaaaacaa cgatttctgc atcttccatt
    75181 aatcggcgaa gccgtgtagc agcagacatt ccacctgcta cacctccgac aataacgatt
    75241 ttcatcttat ttccctccta ctgttcgatc aaaccattga ttcatgccac cacgtacatt
    75301 cactacatca taaccagatt tctttaattc tttagctgct tgtttactcc tcatccctga
    75361 ttgacaaatc acatagacgg tcttttcttt gtctccatca tatctgttta tactttgtaa
    75421 tggaacattt ttagctcctt ttatatgccc gccccggtat tctgcaggtg ttctaacatc
    75481 aagtaacgct ggattttcca aaagcttttc ctttaattct gggactgtta tcgattttat
    75541 tgattgaaat agcaaattca ttttctgcac ctcatttaca tttttataaa tacctcacgg
    75601 ggtatattaa acaggagctt tattaatatg tcaaccagaa tgactcttca tttttttcac
    75661 tactttttat atttgcataa aataccgata aggggtatta tctaattata aaaatagagg
    75721 agaatgtgtt atggagattg ataataaaaa tatcctgaac cgtttgaaac gtacagaggg
    75781 acaaattcgt ggtatccaaa aaatgatcga agacgaaaaa gaatgtatgg atgtcatcac
    75841 tcaattaagc gctgttcgtt ctagtattga tcgcgtaatg ggcatgatcg ttgcagataa
    75901 tctgaaaaat tgctttgaga aacctgatag taatccagaa gaacaagcgg ctaaactaga
    75961 acaagcgatc aagatgatta ttaaaaagta aaggaatgat ttcaatgaaa gtcgttttcc
    76021 atattgatga attagaaaaa tggtcagaaa cagggaaaaa cgtaaaaaac ctgataaaag
    76081 cttctccaga aacgacgatt gtcgtatctg taaatggcat cgcgattacc ggttatctag
    76141 actctgccaa tgcagaattc ttagatttgc aaggagtcgt ttttcacgct tgcgccaatg
    76201 ctatgcgtgc taatcatatt tcagaaagtt ctttacctga acaagtaatc gttgtaccag
    76261 caggtgtcct tgatttagtt gaactgcaat cccaaggtta tgcttatatc aagccttagt
    76321 cagtagaggt tgcgacagaa gtgatcagct tcaagaaatt tcggcttatt tttcgaagaa
    76381 gctacttctg gaaaaccgtg aatcaaaggt tgtgaaaacg ctgtcctgca tcaagtaata
    76441 agaacagcca aacaaaaata gcttctcata tttttcgttt ggttgggctt attaccgcag
    76501 atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa atcagcggtt tgacctaagt
    76561 attagagaaa aaaacgggaa aatagctcct catattttgc cgttttttga gctaataccg
    76621 aaggtcagct gattgaacac cgtttaagga agagattgtg aaaaagtcgc ttagtttcga
    76681 gtattaagaa aaattttgtg aaaatggatt tctacatttt tgcataaatt tggcttaata
    76741 ccgagaaact ggcttttgaa taccgtttaa ggaagaggtt gtaaaatcag cggtttgacc
    76801 tgagtattag agaaacaaac ggaaaaatag ctgctcatat tttgccgttt tttgagctaa
    76861 taccgaaggt cagctgattg aacaccgttt accaagaggt tgtgagccta ccatttaact
    76921 ccgaatcaca agaaataatt tcaaaaacaa cttctcctgt ttttggttcg gttggcttat
    76981 tatcgagaag tagctactgg gagtctattt atcaaaaaaa ggaatgcgac ataggtcaca
    77041 cccctttttt attttctttg aaacatcttt cggtactcga cagcatacaa gacaaaagat
    77101 tgtaaaagac cgtaagtgat gacggcaaaa atgactctca cccacagcgt tggtaattct
    77161 gggaaaagca gcaaaaggat catgccaaca tagatgacag cagtcgctac tttgccatac
    77221 cacttcgctc cacttaattt gatattttta gatagcccga ttaatccagc tacaaacata
    77281 aagccttctt ttatcaagaa tagaccaaac aacagccaaa gccacggtcg ataccatgcc
    77341 atagacaaaa tcagaaaaag ttgtgtcaat ttatctgcaa acggatcaag caccttccct
    77401 aagtctgtta cctgattata tctccgagca atgaccccgt ctagataatc agacaaacct
    77461 gagacaacaa tgaccgctcc tgctatataa aatgactgtc tcagcacaaa ataaagataa
    77521 atcggcagca aaaaaatacg gaatatcgat aaaagattcg gaatcgtttg tatttcttta
    77581 cgccagtctg tgcttaattt cattttatcg ccctacctcc tcagcactct tttcttttta
    77641 ttttagctta cacggggaat aaaaccaatg atttcactgt ttttattttt ctttacagac
    77701 actgatatta tgagctaatt tgagataatc acttgctgtt ttcatcgttt actcttcttt
    77761 cttcctgtcg tttgcgcatt tcttttacta gtactttatg agcttttttt gatcctcgct
    77821 ctaggtcacg ctgccgttta cgtgttttat aatcgataaa cagactgtct aaatcgtaac
    77881 ctgtcgggta cagatcttct gctgaacgca ccagacgaac acgctgacga ggcacgtgga
    77941 ttattttttt gtctaaatat acatcaatcg tatcttcacc tatatcttca taaactaacg
    78001 cttctttttg gtattcattg acaaatatcc gatcaccttt tgcaaagagc tgacgttctt
    78061 ttttattctc cttcctattt gtaactgctg tcttaggaag aaattctttt ttctgtgtcc
    78121 gataggcttt ttccgccaag taacgctctg cttgatggat caatttcatc gacatatcca
    78181 ttttatgagc aatccacaaa gcttggcttt ctcctgtttc ttccaacccg caactgatat
    78241 ttaggacgaa gtgcttcccg atcgaaagcc atagcagccg gcacaaaatc ttcatgatct
    78301 ccggcgaatt tcttgatttc tccataatgg gtcgtggcaa tgatcaatgc cccttgctca
    78361 tacatagatt ccatgattgc gatcgctagt gcagcccctt catttggctc tgttccactg
    78421 ccaatctcat ctaaaagtac caacgtattc ctttttatct ttttcaaaat agcagcgatg
    78481 ttttgcatat gaccagaaaa tgtactcaac gcattttcta aattttggtg gtcaccgaca
    78541 tcgacgaaaa tctcatcaaa gacagcaagc tctgtccctt cttttgccgg aacttgcata
    78601 ccgaacatcg ccatcaaagt caataaaccg actgtcttca acacgactgt tttgcctccg
    78661 gcatttgctc cggtgataat caagcctcga tagtctttac cgatttcaac atccaatggt
    78721 accgcatgct caggtaaaaa tggatgtctg ccttgcttga taatgatatg ttccgattta
    78781 ttgattctag gtgtgcttcc attgatttct cggctaaatt ttgcccgagc aaagatgata
    78841 tctaacaccg tgatcgtttc gatcaataaa tcgatcactt cttcgttttc tgcgatagca
    78901 ccagtcaatg ccgccaggac ttgatattct tcactgattt cttcagcttt taacaactga
    78961 tagtgttcat tcaatttaga aatcacagtt ggttcaataa aaaccgtcgt tcttttattt
    79021 gattcatcga taatcgttcc atctatttta tttttatagc tggctttgat aggaatcgta
    79081 tagtattcgc ctttttgaac aatcattgct tcttggatca tttctttgtt tttcggatga
    79141 cgcaagaatt tcagtaattt tgactggatt tctttttcga ttagttgtaa ttgtttgcgt
    79201 actttacgca aattacgtga cgcgtcgtca ctgactttat tattttttat tttctggtca
    79261 atcaactctt ctacatttat caaatcagga agatgtttgc tataagcaaa caacaagggt
    79321 gtctggtatt gattcttatc aaaaaacttt gtgatcatcc gactgcttct aagaaaatcc
    79381 gcatattcga tcaaatcggt tggctgcaga atcaaccctt ttttgacttg ttctgtcagt
    79441 gcatcgatcc tcggcaaccc cataaatgga acatgctgac tgctttctaa gatcaagcgt
    79501 gcttctcttg tttcttcttg acgatccaag acagtttgta ggtttgtcga gaccgtcata
    79561 tcgctgattc gttttttgct atagtttcca attgctcttg cttggatttc ctttttgatc
    79621 cgatcaaatt gtaattgact aatcatttcg ttgtccatat tctctccttt tcttgaagag
    79681 atacctgtcc caaaataaat aagggcctag agataaataa aaggatagaa cacagcttaa
    79741 aaaagtcatg tcctatcctt attagaatac aaagatattg ttttcctgac aggtaccgtt
    79801 tcataagcac accaaataaa ctttgtttat tggctattcg acttactgat tagataccag
    79861 ctacactcac aaaacatacc ccattcttct aggtcttatt tattttccac ttaactatag
    79921 caagacacat tttggttgtc aaactttagt atgttttata gatttacacc attaatgaat
    79981 agacacctac cgcgataatt gctccgatca ttggacctgc gattggtacc catgaatatg
    80041 cccaatctga agttccttta ttagctattg gcaataccgc atgtgctaat cgaggaccaa
    80101 agtcccgagc agggttgatt gcatatcctg ttggccctcc taatgaaaga ccgatggcta
    80161 agatcaatcc acctacagcg aatacgttcg ttccaggtgc aaattcgttt tgtccaaaag
    80221 ctagcaaccc aagaactaat acaaatgtac caattaattc tgtgatcaca tttgctggat
    80281 aattccgtat agcaggacct gttgcaaacg ttcctaaaat cgcgctttca tctttcgttg
    80341 cattccaatg tggcaaataa gaaagccaaa caagaatggc ccctgcaaaa gctcctaaaa
    80401 cttgcgcaat gatgaaagga acgacaagat tccaactaat tgcccctgtc atcgccatag
    80461 ctagagagac tgcaggattc aaatgagctg ggcccatgaa tccagaaata tagacagcca
    80521 ttgttacagc gagtccccaa ccaaatgcga tgacaatcca gccagaagcc tgtgctttac
    80581 ttttgtttaa attcacagcc gcacacacac catctccaag caaaactagg atcagtgtcc
    80641 caataaactc ccccatgatt tgagtcatat cactgttcat ttatttctcc ccctttagtt
    80701 cccgcagatc tgattctgca atcaatgctt ctaaacgttt agtctgttgc gccttctcct
    80761 cttctgtcca ttcaaaatat ccagcaattg catcgatcac aggttgcttg atctcatcaa
    80821 gctgatctcg ttcaaacaac agatgatttg tacgacgaat gagataatcg cctggggcca
    80881 aaaccatttc ttcttctaaa ccataacgta accgagctga ctcagcgaga ctcaaaccag
    80941 gataaggtgc catttctttt gctaattcaa agatacgtcg ggcattagtc ccgtaaaaat
    81001 cagcgatata agtagcatct tcttcctcta aaccggctgc tactccttct tttgctaatt
    81061 ctgtcactgt ttcttctaat ttagttggat cgaagtttcc acctgaaatc tgatattttt
    81121 tagagtcgat ttctttcgtc tctattccgt attcttcttt taataattgg cgtatcaatc
    81181 gcaaagctcc ttctgccatc ttacggtaat cggtgatttt cccaccagat aaagtcagca
    81241 aaccatctgg ttctctttct aaagaactac ctctggaaat cgtagaaggt gctttttcat
    81301 cacggctgtt ttccaaatgg ttcaacacgt cttctacttc agcacgagaa actttgtttt
    81361 ccttatattc acttactgta tcgacaactt tattgaagct cttgtctgaa atcgatccat
    81421 tatctccacc attgtaatca gaaccagaat taccaatcaa cagtggacga agtcctgccc
    81481 agcttgcttc gatatcattc aatgtgatat ttgcttctgg atagcgatga ttgatcacat
    81541 ccaatagata atctacatct tcttgtgtga ctttcggatc cgtaaaatct ccttggtaat
    81601 ccgtatctgt cgtaccaaag taagtcttgt tttctcttgg aatagcaaaa accatccgcc
    81661 catcttgctt tcctgtatcg aagtatgtgg gttgcggtac aggcagtttt ttcgcatcta
    81721 caactaaatg gatcccttta gttggacgca ttttaggaga gactggacgc gtaaaattca
    81781 agtttcgtac tttatctacc caaggaccac tcgtattgat cactaatttt gctttgattt
    81841 cgatcacttc atctgtcagc aggtcacgag ctttgacgcc aacgatttga tcgccatcat
    81901 ataaaaagcc aaccgctttc attttactta ctagataagc cccatcttcg gcagcctttt
    81961 tgatattatc aatcactaaa cgggcatcat tgttgcggaa atctagatag acacccgcgc
    82021 cttttagccc ttcttttttc aaaaacggtt ctctttccaa tacttcttct ggtgtcagcg
    82081 tataattctc atatttggtt cctgtcacat ttgccagttt gtcataaagg tccattgcta
    82141 ctttgaccga gaacatattg aaggttgttg ctccttcgcc ctcatagatt ggcaaaagca
    82201 ttggatctgg ttttgggatg tgtggggcaa tactttgtac gactgcacgt tcaccaactg
    82261 tgtcagctac tacttccaca tcaaatgtct tcagataacg aataccgcca tgaacaagtt
    82321 tggtcgagcg agaggaagtc ccttctgcaa aatcctgcat ttcgatcaat cctgttttga
    82381 ttcctgatgc tgctgactgg actgccacac cggcaccagt gattccgcca ccgatgatca
    82441 acagatccaa ttcttcttgc tgcatttttt gaatgctatc ttgtcttgtc ttgtttgaaa
    82501 acatatggat ttcctcctta ttcaaatgct tgggtagctt ttactgcttt tttccaaccg
    82561 ttgtaaagtt tttctcggcg ctcttcctcc atttgaactt caaatagctt gccagcttca
    82621 taaaattcgc ggatctcgtc tgtatctttc caataaccga cagctaatcc tgctaaaaat
    82681 gctgccccta gcgccgttgt ttccaagttt tctgctcgtt ggatcggtac attcaagata
    82741 tctgtttgga attgcatcag atattcattg tttgctgcac cgccatctac tttcaataca
    82801 ggaatcttga ttccagtgtc atcttgcatc gtatcgatga tatctctcac ttgataagca
    82861 atcgactgta aagtagcttt aatgatatct tcttttgtcg taccacgtgt caagccaaac
    82921 atagcccctc gtgctgcctg atcccaataa ggagcaccta gcccaacgaa tgcaggaaca
    82981 acataaacct catcttcgct tgtagagcgt ttcgctgcgt cttctgaatc gctagctttt
    83041 tgcaacattt gaagtccatc tctcagccat tgaatcgaag aaccagccac aaaaatactt
    83101 ccttctaaag catagtaaac ctttccattt atgccgtaac caattgtcgt caataaatta
    83161 tttttggata attgcggttt ttcaccggta ttcatgacaa taaatgaacc tgtaccataa
    83221 gtattcttga ccatgcctgg ttcgaatgcc atttgtccga ataatgcggc ttgctggtct
    83281 cctgccatcc ctgaaattgg tgcttcgctt ccataaaaat gataaccttg cgtataacca
    83341 taaacttctg agttagaagt gacttttggt aacatcactc gaggaatatt tagtaaatct
    83401 aaaatctcct gatcccaatc tagctgatgg atattgaaca acatcgtccg actggcattc
    83461 gagtaatcag taacatgtgc ttgtccatcg gtcagtttcc atactaacca agaatcgatc
    83521 gttccaaaca tcaattcgcc tttttcagct cgttcttgcg cgccttctac atgatcaaga
    83581 atccagcgta tcttcgttgc tgagaaatag gcatcgatca ctaaccctgt tttttcgtgg
    83641 aaaaattctt gatagccttc attttttaag ttatctgcaa ttccagctga ctgtctggat
    83701 tgccaaacaa ctgcatgata gattggacgt cctgtatctt tttcccatat tactgttgtt
    83761 tcacgctggt tcgttatgcc aatcccagca atctgatttg gtttgatccc tgattcgatg
    83821 aacgctccgg caataactga ctgtacagaa ttccagattt catttgcatc atgttccacc
    83881 caactttctt gcgggaaata ttgcgtgaac tctttttgag aactgccgat gtgtcttcct
    83941 ttcttgtcaa agataattgc tcgtgagcta gttgtacctt ggtcaatcgc catgatatac
    84001 gttgattctg tcattgtgat tccctccatt atatgcaaac gctttcttta actactctta
    84061 tcatactact gttttaaaaa aagaaactgt caaaatttta ttcttttttt ctttttttga
    84121 cagtttttta ttatgaagct attttttaat caattctttt cttttttcag cgtctctatt
    84181 cttcttttca atcgaataat gtcgtaaggt gacgcaaatt ctgacagata atattcacac
    84241 tgttttttgt ttctctggca aaatgtgatc accaaatcat attctttacc ttcttcataa
    84301 cttccaatct caataccgcc gattcccctc agttctctga tcagatattg ttgaaaagca
    84361 atacgataaa tcggcagact ttctaaatcg attccaatca ctactggttt tgcaatataa
    84421 aaatcgatca tcaaaagaac attggcatac tggatcatca ggtaactaag ctcactatct
    84481 tcagctcttt tcctcggcaa ttgctgcacc gctgtttcct gtaatttcgc cagtaactgt
    84541 gttaaggaat gcccgagcat tttctgctgc tgttccaaaa gccgatcacg ctcatagact
    84601 tcgatctttc caacaaagaa aaaccattca ttgttgatct gggaaatttg gtagcctact
    84661 gccttttctt ctttgatttt caaacgacga ggacgataat gccataacat cgtttcccga
    84721 atgtaagtat ctaaaacagc ggttggtaac tttttgctcc gtgtcaaatc atactgataa
    84781 aatatttctt cgtctactat cgaaaaagaa acaaaaaagc tgtaaaacat cattgtttcg
    84841 tatacattca gttctgctgc tgttcgacta agatgcatca cgatgattgg atcgattgct
    84901 tgataaagcc ggtccgactg atagagtaat ttcttttctt tcaaagttgc gtacgtactt
    84961 ttttcattca atagtctttt tttcgtaatc ccgagccagc aagcaatctg tgcttctgct
    85021 gatgccgtaa acgttgtttc taatacacgg tccaatccta gaatgaacgg tcttttttct
    85081 ggtgtatttt gcaaaaaaag cggtcgctga tcttccggga tatattggaa tagttcataa
    85141 taaaaatatc gtatctgtag ctcttctccg tataattgac cgtttttgat ttgtaatcca
    85201 aattcctcta agagctggtt caattctttg atctttcgaa aaacagaaga ctcactgata
    85261 ttaaacgctg tcgctaatcg aacgatggat acttgctgat gttctaataa atagacgagc
    85321 atcttaaact tcaagctttc ctgcaataaa aacaatagaa ttttttccaa acttacatct
    85381 tcgtccaaca caagcagcgc ctgatactca tttcgctgta cttctacttt tttttccatc
    85441 attcggccaa tcaattcaat atcttccaaa tattgatcaa acgaggcttt tgacagttgg
    85501 acatgctctc tcaaaccatt gatagaggct gttccccctt gcagaacaag gtttcgcaaa
    85561 atcaggatct gtaactgctc ttttctttct aataatgctt caatcttcat aggcagtatt
    85621 cgccaccttt gaccacacca tatctggcac acggtattct ggctggaaaa atagctcatg
    85681 ttcttctaac tgttcaaacg tccatccttc ttctactgca attgtcagtt ggtcaagaag
    85741 gtggaacatc tcttttttgc tttggagctg tgctccaaga atcttttttt cagaatcaaa
    85801 tagaaatttg agtttaactt tgctttgatt tattgctgta agcttgtagt ctacgtatcc
    85861 tgtttcaatt ttttggggat aaaaaatgct ctcttcttct gtcaaaccta cgcttcctaa
    85921 gaaatagcca aaccactgat tgccgactgg acgataggtt ccctgatcct ttgtctgtga
    85981 gccactaatt gtcttgctga catttcgtgc tgtacggaca gcgttattta ctagagaaac
    86041 atacattttt tcatttgttg gacgaaaagt tacttggatc gcatcgccaa tcgcataaac
    86101 gtctttttga gacgtttgca agtagtcatc tacccagatc gttccatcat cattcaatgt
    86161 taattgttct tcccacatct gattgtcggg acgagaatga ttagccagca aaacaagatc
    86221 atagttctcc tttctttttt ccgtctctac aatagcggtt tcattttcgg tcaaagacac
    86281 aacttgttct tctaaaaaaa gtgaaagccc ttgatttttc atttccttta ctaacggttc
    86341 tgtcatttca ggatctagat aacgaaaaag aattgacttt cggctttcgt aaagatggat
    86401 ttgttttttt cttgatgcca acccttcagc tatttcgatt cctgcttgtc ctgcaccaat
    86461 aattgcaatt ttctttgcat tcatgatctt ttgctgaaga gccgttacgt tttgtatctt
    86521 tttaactggg tgaataagcg ttgattctgc agaaatattt cgaaactttt gatttgaacc
    86581 agtcgctaga atcaaacgat caaaatccaa tttttttcct cctgctaaaa cgactttttt
    86641 ttctttcaat cctattactg tcttttctgt gtaaacatgg attcgatagc ggtcagtcag
    86701 ttcttctttc gtgatccaag aaagttgttt ttcactggta acctttcctt ttaatatcaa
    86761 attgaacccg ctgggaatcc atcctaactt cgattgcttt tcaatcaaat atatttcact
    86821 tgttggcatc aattggcgaa gataaatagc cgcatgaatc cctgcaaacg acccgccgac
    86881 aattacaatg ttcatctgca ttcctctttc ttataaggtg ttctactgct aacttctcaa
    86941 tcagaaaaca cagtattcat aactcgcttt caaccttatg atacatagcg atgcagcaga
    87001 atcaaccctc tccatcatac cgtgttctag gtctgcttct caataatgta ctagtggacc
    87061 taattgaaga gtatcatttc tgaagagatg tttcaaaaaa tgtactctta taaaagaaaa
    87121 aaactcgcct tttacgtacc tctgtccaaa taggaaacag aaaagaacga aaagacgagt
    87181 tttagcgtgt gtaatgtaat agttagaata gacacatcat ttatttttaa ttctttaatg
    87241 cttcaacaac tgcttcgcct aattgatgag cagattgagg attttgccct gtaagaagcc
    87301 gcccatcaat ttgaaccact tctgaaaaag ctgctccaga ctgatagttt gctccttttt
    87361 ctttcaaagc atcttctgct aagaatggta cttcattcgt tgtaccattt gcttcctctt
    87421 cttcattact gaacccagtc actgtacgtc cagctaaaat agattttcca gactcatctg
    87481 taactggcaa caatcctaca acaccgtgac aaacagctga gaccagccct tcatttcgat
    87541 agatttgtga agcgactttc ccaagatcta ttgcttctgg aaaatcccac attgttccgt
    87601 ggccaccagc ataataaacc gctgcataat catttgcatc cacatcatca ggacgtaagg
    87661 tatttcccaa ggcccgattt ctgaaatctt catcttcata ataggcccaa tcgatttcat
    87721 ccatattcaa aacactttgc ggttctaaag gtacatatcc gcctttagga ctgacaaaat
    87781 ctgcatcgat cccatttttt actaatacat cataaaaatg agtcagttca cttaaccaca
    87841 aacctgtagg acgctcgatc ttttcgtact tttctacatt tgttaatacg atcaatactt
    87901 tcattttccc atcctctttc tataaaaatt gcgttattga taacgtgctt tcaagaaatt
    87961 atataatggg cttggcaaat aaagctcttt atatgcttct tcaaaaggtt tcgttacaaa
    88021 ttcatcctca cggttttcca ataatttctc tgcccagtca ggatcgacga tcatttgctg
    88081 tccaattgct gcaagttctg catatttcaa tacctgctct acatcttcgc gattgcggat
    88141 cccaccgaca ccaactaaag ggatctttcc ttgaatcgtg ttatggacca cttcaagaat
    88201 cgatttatcg ttgtatttat cagaacgagc tattcgatca tacatattta atgaaacatg
    88261 cagataatct agttttgact cacgtaatcg ttcaagaagc cagatcgtgt cttcaaaacg
    88321 gatacctggt gtttcatatt cttctggtga gaaacgatac cctacgatga atggtttttt
    88381 agcatattgt tcaaccgctg agaaaaccgt tgttaataat tcttcaataa aacgataacg
    88441 attttccaag ctaccgcccc attgatcctc tcgtctattc gaatgcggag agaaaaattg
    88501 ttggatcaaa tacgtatttg ctccatgcaa ctcgattcca tcaaatcctg attcaatcgc
    88561 tctacgtgtg gctttgccaa atgcttggat tgtttcaacg atttcttctt cactcattgc
    88621 tcgtggtgtt tccgcatcag gacgttttgc tgcaactgca cttgcagata caggctgttc
    88681 tccagataaa gttgctcgac ttgtcattcg tccaccgtgg aaaatctgaa taatcgcttt
    88741 tgcgccttct ccttggattg ctttcgctag ctcacttaat cgaggaatca tttcatcatg
    88801 agcgatgctg agttcacctg gccagccttt tccgatatct tggacatttg cagcaccagt
    88861 aataacagca ccaagacctt tagaacgttg tttataataa gtgatctcat cttcggtgat
    88921 cactccattg aaaaagctga gttgtgtcgt cataggcgac agcatcaatc ggttcttcaa
    88981 ttgaactcct gaaggtaaag taattgattg atcaaattgt gacattgtca ttcctcccat
    89041 aattcgctct gattaaccta tcgagaatca tctatcatta aaccactcga ttagttgtac
    89101 atgcaactaa tttgcttaaa aaattttatt ttttttgtaa cttatctgtt gcatcattca
    89161 ttgtctgggc taattcttta cttgcttcat ttcccaaaac tgctttgtat gactgatgaa
    89221 gttcttccca gctaccatcg acttccttag caaattggcg tccttgttct gtaagataaa
    89281 ctaatgacaa gcgaccttcg ctaactgttt tgacgtatcc tttatattct aatttttcaa
    89341 caaaacgagc aatcgttgat ggggcggaat agagcatttg tgcaatatct ttttgtggta
    89401 ttccatcttt ttcttttaat atcaataaaa taaaaccata agttggtgcc agacctgtcc
    89461 ttctaaacgc ttcatcagct aatttattca acatgcgatc tagctttttc acgctaaaga
    89521 aaagacattc atctaacgct ttttcaattg gcttttccat ttcatcccct ccattggcgt
    89581 acatatcata gtatgatttt tattttttgt caaaaaacac ggaataatgt ccgcctcctc
    89641 tgtctagatt tgaaaaaaag aagtagccat cttcaaagaa tttcggcttg ttttcgacaa
    89701 aactccttct ggaacaccgt gaatcagagg ttgtgaaaaa gtcgtttagt tttgagtatg
    89761 aagaaaaatt ttgtgaaaat ggctttccac atttttgcat aaatttggct taataccgaa
    89821 aaactggctt ttgaacaccg tttatatcag aggttgtgaa aaagccgtcc tgcatcaagt
    89881 aataagaaca gccaaacaaa aatagttcct catattttgt cgttttttga gctaatgccg
    89941 atggtcagct gattgtacac cgtttattga gaggtcgtga gcctgccgtt gaactccgag
    90001 tcacaaggag caatttcaaa aaacagcttc tcatgtttta tgactatggt gacttgtgat
    90061 cgaggagttg gcaggagaat actgtttatt cgtaaagaag gggctgtgac aagacttttg
    90121 tcacagtccc ttatttcctt ttattatagg atttcgccat ttgattggat gacttgtctg
    90181 taccaatcaa atgatttttt ctttaaccgt ttctttgtgc cattcccttc gtcatcttga
    90241 tcaacataga tatatccata acgttttgac atttgtgaag tagaagcgct gacgatatca
    90301 atgcagcccc acgacgtata accaaataaa tctactccat ctttgatagc ttccttcatc
    90361 tgctcaatat gctgcttcaa atagtcaatg cggtaatcgt cttgaacggt tccatcttct
    90421 tctactttgt ctatagctcc gagtccgttt tcagctatga acagtggttt ttgataccta
    90481 tcatataatt gattcaaagc aattctcaaa cccttaggat caatctgcca gccccattca
    90541 cttgatggaa gatacggatt tttaattcct ccagttatta agtttccttg gaccccttcc
    90601 caattttctg gatgagcact gactgcacta gacatgtagt agctaaaaga aacaaaatca
    90661 acagggtagg ctgctaagat ttcttcatca cctacttcta tttttaagtt gacacctttt
    90721 tcttcaaaca ttcgttgcgt atacgctgga taatatcctc ttgcttgaac atcactaaag
    90781 aacaaagaag ttctttgctg ctcaattgtt ttttgaatat catccggatc acaagaatac
    90841 ggaacaagaa gctgatagct gatcatacaa ccgacttgtg aacctttgat aatttcatga
    90901 caagcttttg tagctaaagc acttgctata aactgatggt gtgcaccttg gtatttcgct
    90961 tgttccaaat ggggatggtt ttcttcaatt actcctacgc taacaaaagg gtgatgtttt
    91021 acacagttga tctcattgaa agtcatccaa tattttactt tatttttata gcgtttgaat
    91081 actgtttcag cgaaacgaac gtaaaactga ataagctttc gattaggcca tccaccatat
    91141 tctgtaacca aatataacgg catttcataa tgggaaagag aaacgactgg ctcaatccca
    91201 tattttagac attcgtcaaa cacttgatca taaaaaaata atcccgcttc attgggtgtt
    91261 tcttcatcac catgaggaaa aattcttgtc catgcgatag acatccgata gcatttaaaa
    91321 cccatttcag caaataaacg gatgtcttct ttaaagtgat gatagaaatc atttccgtgt
    91381 cttttaggat aataatactt gctgttggga tcctgcgccg cttttacttg ctgatgcgtc
    91441 atcatatgcc attgatctgt ccatttttct ttaggtaaat cgctgtcgaa tgtatacaca
    91501 tcagacacag ataatccttt ttcatctaca tcccatgcac cttcacattg attggccgct
    91561 gtcgctccgc cccataaaaa tccttctgga aattttttca tatcgatccc cctaaacttg
    91621 ctagttttct tgtttgatta tttttcttat gactagtaat gatatttttg aatctactac
    91681 tatttgtaac aataaccatt gtggtcggat catatccctc tttgattaat tcttgcaaat
    91741 ctacttccat caataaatcg cctttacgta ctttttttcc atcagatact gcactttgaa
    91801 agtatttgcc atttaaattc actgtatcaa taccgatatg gatcagtatc tctgctcctt
    91861 cttcactgac taccccaatt gcatgtttcg ttggaaaaac tgttgaaact tccccgttta
    91921 cagaactgta gatttttccg tccgttggaa tgatcgcaaa cccttctcct aaagatccac
    91981 tagcaaatgt tggatcgttt acttcagata aatcaattat ttcacctgct gcaggagtac
    92041 ttaacactat atcctttgag gattcttctt cgatttcatc cttgtagccg aaaagaaaag
    92101 ttagcataca ggaactgatc atcgctaaga aataactagc aactagccaa acaaatcctt
    92161 caccaatata aatcgggaaa gacaaaatac ttcttgtagc aactgccaaa gcaccggctc
    92221 ctgcggcacc agctactcca ccaaatatag ctccacatat acaagcaatg taaaatggtc
    92281 gtttatattt aagagtcaca ccataaacag caggttcagt gattccaaat aatgctgtga
    92341 taaatgcaga taaagataaa ctttttactt tcttattttt cgttttcaaa aataccccaa
    92401 gtactgctcc tgcttgcgca gctacggcag tcatacatgc tggacctagc gtatcacgac
    92461 cgtagaaaga aagattgttg gtcattactg gtacaagtcc ccaatgtaac ccaaaaatca
    92521 ctaacacttg ccaaaatccg ccgataacag caccagataa aacagggcta aagttataaa
    92581 cagctaaata tccagctgca atcagctgac ttgcataatc tgcaattgga cctacaacta
    92641 ataaaataat tgggaccatc acgatgatac aaatgaatgg tgtcaataaa tttcgaatac
    92701 tttcgtgcaa gcttttgcga atcttaggct caatataaga aagaacccat acagctaaaa
    92761 ttgctggaat aaccgtactt gtataccttg ctagaatcac gggcatccct agaaatcgca
    92821 aggttatgct atcactatat gcactgacaa tcgtaggata aacgagagct gctgcaataa
    92881 ccatagcgat gaaacgatct gtattgaact tttttgcagc agtatatgcc aaaaatatag
    92941 gcaagaaata gaaaaatgca tcagctgctg cattcaaaat gatataagtt cctgattcag
    93001 tagttaataa attcaaactc gtacataagg cgagtactcc tttgatcaaa ccacttcctg
    93061 ccaagacgcc taaagtcggg gcaaaaacag cggcgatcat gtctataaaa gagtttaaaa
    93121 tgcctttttt ctcagttcct ctctttccac tagatgcatc atcttctagt ttcatttgtt
    93181 tggataatac gtcatacact tcatttactg catttcctac tacgacttga aacattcctc
    93241 cagcttcgac tacagtgatc acaccttcta gttgctctac cttctcctta tctgccttct
    93301 tattatcttt tagggtaaag cgtaaccttg ttgcacaatg gtaaacattg ctgacatttt
    93361 cttcgcctcc gacaaatcgg acaatatctt tcgctaattg tgaatagtcc atttttactt
    93421 cccccttgtt aattaatgcc gtagcaatcc ttcttacaag ataagtatag ttcttagaaa
    93481 acggtttctc cattcaatta gtaccccttc taatagcgaa cgaaactgta caatagtgtg
    93541 tatggtttac ttagccgagc aaatcactca ctgcttgaaa gaaaacaagt atatcgtttc
    93601 tcttatagtc aaaggagaca aaaaaaacac gcttgatctt cctttgctga tgtataagtg
    93661 gtatctcaag ctgatactct gtgatttttg tttctacttg gcttttgata agacagcaca
    93721 acaaagtctc ggcatttaac ggaagcataa ctaggtcaga actaggagag attagttgct
    93781 gaatggaatc tatcttttta tggattttta tttgattttc ttctttgtag taatgatcaa
    93841 gcagttttgt tttctttttt tcttcaacta tggtcagctt ttcacgcaaa atctgataaa
    93901 tctcccaaga ttcaaactca tctagaacac taggtagata aatcaaatca tcccactcaa
    93961 aaataagctc ttgctcagta gtcaaaattg catcatattc cgttattttg tttgattgat
    94021 ttttgaaaag atacactggt tctatccggc attctttgat ccacatgttc atactttgtt
    94081 gaatctgttt ttttagtgta ttcaaaatac taattggctg gttactaaca atcagtatct
    94141 ccccttgttt tcgaaaagga ttcaacgctt cggcaagata caaaacaaaa taagcgcttt
    94201 cagctaaatt gggacgtaat tgaaaatgta ttgggaagaa acgccgaatt aaataaattt
    94261 ctaaaggata acgggagatg atcttttgta caaaatgatt catggtatta tgtccggcat
    94321 ccatcctcgt tttcatttgt ttgatatggg ttagcaaaaa ttctgtttca tggaacaata
    94381 acgaaacagg aagatctaaa aaacgaataa tcgtttgctc aaatgctctt agattcttct
    94441 ctatttcttt gtttttttca tcattaatca tcaaataatt taactctaat agtcgatttt
    94501 caattgcttg tttttcttga ttggaaaaag aatagggtag ttctgatgat aacttttttg
    94561 tgagggtctc taccatcgga ataaataatg tatacctgtt tgttttttct aaaagttctt
    94621 ctcttcgaag aatggtcaaa acgagatacc gagaaaatcg tatgaagtcc tctcctgaaa
    94681 caatataatt atatgatata agaacctctt ttaatgtctt ttggacagtc ggcatgatat
    94741 tggaaaaaat tgtactgatt tgttgaggaa accttgcgtg ttggatcacc gtttctgttc
    94801 caacaagaga taagaaaatt ctttttgaat tttcttcagc aatgattttt agtccttttg
    94861 tcgacgaaac ttccagttct aatttaggat tgcgctcgat ccaacgcaaa atcgttttta
    94921 tttgtaatga tacggctgtt tttgaaagaa agaaaatgtc tgctatcttt tgcatactga
    94981 catacccttt ttgaaacaat aagtacgtca caatagttga agctcggaaa tccatgctgg
    95041 aatagatttt atgtttcgtc acctcttgta tgatttgctg tttagtttca gattcaattg
    95101 attctaaaaa ataacctgaa cgtttatttg actggataat gattttcttc tcgtagatag
    95161 caagcatatt tttgatttca gtttggatcg ttttcttgtt ggtacctaaa gcttcagcta
    95221 attcttcgct tgttatccaa tgattcttat ttcttaatac tacaagaatt tggagttgtc
    95281 gtttatttaa gtccatttgc ttacacctcc tctttgttat aaacatacag gaaaaacctc
    95341 tcaaatgaca atagtcactt gcagaggttt aaaaatcatt tgaagaaaga tctatattca
    95401 aggtttttac cattagactg gataatttgt ttataatatt caaaactatc ttttttcaat
    95461 ctcctaaagc ttccgctccc atcattttgt ctatccacat aaataaagcc atatcgcttc
    95521 ctcatttccc ctgttcctgc cgatacgata tcgattggtc cccaccataa gtaaccaatg
    95581 atttggcaac catcttttat tgcctcagca atttcctgaa gatgtatttt tagatactca
    95641 caacgttttg gatcgtggat tcgattcaat tcatctggtg cttcatctag tccaatgcca
    95701 ttttcaacta tgaataatgg taattcataa cggtctgtca attcattcat gacataacga
    95761 aaccctagag gatcaattgg ccaactccaa ggttcgggag atttttcctt caaaaaggga
    95821 ttatcgaaac catttgctcc gccagtatct acgcgcattt ctgcttcttt tttatagaca
    95881 gcgctacgat aataactaaa tgcaatataa tctgccgtgt tagcttgcaa gcactgttcg
    95941 tctccatcta acattactgg tgcacagtct tcttccttcc atgtcctgta aatataagct
    96001 ggataatgcc ctcggcacat gacatcggag aaaaaccatg aattgcgttt aaattgcagt
    96061 gaaccaaata cattctctgg atcacagtca tatgcataag tcgctaatgc agaaaagcta
    96121 cacataatac ccatcttagc atttggatcg attttcttta ataattgagt agcacgggcg
    96181 ttcgctagaa acatatgatg acaggcttga taaatcactt tttttgttag tgtagcaatg
    96241 ggttcaagtt tatctctagc agggaatgta accaatccag cagctgcata aggcatacga
    96301 aaagcattat tgatctcatt aaaggtcatc caatatttca ctttcccttg gtagcgttca
    96361 aagacggtct gcgcataaaa ttcaaaaaag tcgattaatt ttcgattttg ccacccccca
    96421 tactctccta ccaatgctaa gggggtttca taatgactaa gagtaattac tggctcgata
    96481 tcatatcgat ttaatgtatt gattagtctg tcataaaata cgagaccagc ctcatttggc
    96541 ttctgttcgt ctcctcttgg aaatattcgt gcccatgaga tgcttgttcg aaaagctttt
    96601 aaacctaact ccttcagtaa acgaatatcc tcttcaaatc gatgataaaa atcaatcgct
    96661 tcatgagaaa gataatagag tgattcgtct aaagcaatct cccaaatctt tttttcttca
    96721 ttccactgaa tactaggatg ctggttcatg atcccgataa gcgtatctgt cacattaggt
    96781 aatttgccgt cttccaacca tgcaccttca cattgattag cagctactgc tccgccccat
    96841 aaaaaatttt ctggaaatat ttcctgatcc ataactatct ctcctcgcta tcaacaattt
    96901 cttacttgaa gtatagctcg attcatcaaa acaagatatt ctaactattt cggcagaaga
    96961 gaagaaaaaa attgaatgct actcttcatt tttaatattt atatataaca aatacataag
    97021 acgatccccg aaagaaaaca ctcgttaacc atctaagcaa acgatttatt ttacttccaa
    97081 cacaaatgct tcataaggtc gtaaatcaac tttgccgtct ggtaactgtt tcagaggata
    97141 atttgacaca ataaccctta aagcttcacg tggaatagtg aacgtctgct tttcactgga
    97201 catattacaa ataacgagcc attgctggtc ttcatatatg cgagaatagg caaagacatg
    97261 ctcaggcgtc ttttccacta attcatagtc tccccagacg atgatgtcat gttttctacg
    97321 caaatcgatc aatttcttgt acatataaaa aacagaatct tgatctgcta acgcttcttc
    97381 tgcattgatt tctttataat ttggattgac tcgaagccat ggaattccag tagtaaaccc
    97441 agcatgttca cgggcgttcc attgcatagg cgtcctagca ttgtctcttc ctttcgcctt
    97501 gattgattcc aagatttcct cttttgtaaa tccagaagaa atcctttcgt tatacatatt
    97561 gattgtctca atatcttttg cttccgcgat atcatcgatt gggcaattcg tcatgcctaa
    97621 ctcttctcct tgatagatat aaggggtgcc tttcatcata tggagcaaga tagcaaacat
    97681 cttggcactt tcttttcgat acacatcgtc atttccccaa cgagaaacaa ttcgcggaag
    97741 atcgtgatta ttccaaaata aactattcca tccttcatca cctaaagatg tttgccattt
    97801 ggataatact tttttcagtt cagagatact caagggtttc aaatcccatt tgtctttgcc
    97861 ttcttgctga tctaatccta tgtgttcgaa ttggaagacc atggataatt catttctttt
    97921 aggattggaa taaagtttag cgatttcggt agttgctccc catgtttcgc caacagtcat
    97981 cagatttttg tcaccaaaag ttgcttgatt catttcctga agatactcat gcagtttagg
    98041 tccattactt gtgatttctt tatccggttc tttgccaatc atatcgatca cgtccatacg
    98101 aaagccccca atacctttat cgatccagaa attcatcatt tgataaatct cttggcgaac
    98161 ctgtttattt ttccaattca aatcaggttg acgcttgcta tacaagtgca gaaaatattg
    98221 ccccgttttt tcatccaact gccaagcaga accactgaat attgagcgca atctattagg
    98281 ctcttttcca ttgaccggat cacgccaaat ataatagtcc cgataaggat tttctttatt
    98341 tttacgggcc tcaatgaacc acggatgttc atcagaagta tgattcacca ccagatccat
    98401 gatgatacgg atatttcttt tctttgcttc ttcaatcagt tcttccattt cttccatcgt
    98461 accgaattct gccatgattg cttgataatt actgatatca tacccattgt catcattcgg
    98521 agactcgtat actggagaaa gccaaattgc atcaatacct aaatacgcca gataatccaa
    98581 cctggaaata atcccccgca aatctccaat accatcttga tttgaatctt gaaaacttct
    98641 tggatagatt tgataaacaa ctgaatggtg ccaccatttt tgttccatga ttttcctcct
    98701 ataaatggat gtttctattt tttgcttaat catttatttt agtctctctc actaaaaatt
    98761 gtaacgcttt caaatagcta ttgcaccttg ttatcggtaa cagaataaaa caaaaaaaca
    98821 gctgaggaaa ttccctcaac tgttttttga aaggattgat ttatgcaggg aagaatgctg
    98881 atttcacaac ttctttataa acggtgttca ctcagctgtc ccttggtatt agctcaaaaa
    98941 acggcaaaat ataagaaact attttttcgt ttttttctct aatactcagg ccagaacgct
    99001 gatttcacaa cctctttatt tcacattcaa tatccacatg aatcccacaa atacaaagaa
    99061 cagaccatac atgattggag atacttcttt tcctctttta gctgctaaca tggtaattgg
    99121 atagaagata aaacctaatg caatcccatc tgaaatacta taagtcaaag gcatgccgat
    99181 caagatcaag aatgaaggga tcgcaatctc taagtttccc cattcgattt gtcgcaaaga
    99241 ttgtgccatc aatactccta ccataatcaa tgctggtgca gttacttgtg aagtaacaac
    99301 tgatagtaat ggagaaaaga acaagcctaa caagaagaaa atccctgtag taatagctgt
    99361 gatacctgaa cgtcctccaa cggcgatacc agctgatgat tctacaaatg caccaacagg
    99421 agaagtacca aataaggaac ccgcaagcat agctgttgaa tcagaagcta aagctttccc
    99481 tacacgaggc atcttgttgt ctttcatgaa acctgcttgg tttgctaatc caactaaagt
    99541 tcctgctgta tcaaagaaag tcacaagcaa gaatgtcagc actacgaccc acatttgaag
    99601 agaattgatg tcccctacat gttttaatgc aactaaaaat gttggtttca aacttggtgc
    99661 tgcggcaaca atttcagaag gcattggaat caaacctgtg accagaccta aaatcgttgt
    99721 agctgccatc ccgatgaaga tgccacctgg tacacgccga acaagcaaga tagcagttac
    99781 gactaatcca aaaatcgtca accaagtaga accaacgttg agtgatccta atcctactaa
    99841 tgtagattca ttcgaaacga tgatcccacc ttcgctcaga ccaaggaaag cgataaatag
    99901 accgataccg ccagaaatcg catatttcaa atctgctggg atcgcatcaa tgatcatttc
    99961 ccgcagcttg aagattgtga tcaaaataaa aatcaaagaa gcaacgaata cgccggctaa
   100021 tgctgtttcc catggaatcc ccattcctaa acaaacagaa taagcaaaaa aagcattgat
   100081 cccaagagca ggtgccgttc caattggata acgggctaat acccccatta aaacacagcc
   100141 gatcgcactg gctaatgcag tcgcagtaaa cactgctcct tcatccattc cagaagcacc
   100201 taatacagtt ggatttacaa ataagatata agccattgag ataaatgttg taaatcctgc
   100261 cagtacctca cgttttaccg tggtgttcaa tttttctatt tcgaagtagg aaagtatttt
   100321 ttccttcatc ttccatcccc ctaaatccga acattataaa taaagtccgt taaaatttcg
   100381 atttattaat aaaacaacgt gttttatcat atactaaaac aaaacataag taaacaaaaa
   100441 attcggattt taagcaaaat ccgaacgttc catctgatta aatcccttta tctcaaagtt
   100501 catgaacatt cactttggat tacaagaatt tctttattgt gttaataaag tttcttcatt
   100561 ctagtctcaa aaatcaatag tgtgatttga ttttaccatt tcgtttctgt tcttctttga
   100621 tgaattcttt tgtatcgaca ggattcagat tatttagtcc gccaaaacct gtatcgacca
   100681 tttttcccca gccttttgtc ttcttttttc ctgatttgag attctttgct cgaagcttct
   100741 cactatgttt tgctcgccga tacttcaaat aaccttctaa tcttcccatt agatccactg
   100801 tttttcctcc tttttattca atcagacgac tcagcttttc ctataacaaa ataattgcct
   100861 tcagggtcag aaaaattgaa agtcaagatg ccattgttat ctgtgatttc tcctggttct
   100921 tccatgttct cgtagatagt ttcaaattca tccgtaaaaa atactaaaga aggcggtggt
   100981 cctaatacct ctggtgaaaa cttctgcaca aatacttttg ggaatacgcc taattctaat
   101041 tcttttgaga tgctgagtac aatactctta aattcttctg gcaattcgat tgtttcagaa
   101101 atttctgcac caattttttc tacaaagaat cggcaaatca tctctacgtc attgacataa
   101161 agcatcacac gtgttttttg tatcatcatt tgacccttct ttctatttga ttttctttcc
   101221 tgtctataaa ctgattccat tatatcacga aagcgcaaac accttgtgtt tgatactatt
   101281 caagaaaaat aaagcaatag tttctaggat tgctttcctc cacaaacttt ttttacaaaa
   101341 aaaaaacggc aatgaatgcc gctcttctta tttcgattct tttataattc tgcttctgat
   101401 tcatctttgg ttagtgtgtg tctaacacta gttacgccaa atgtttgatc gattttttcc
   101461 ttcaacgctt cgattgcctg tgcgccacgt gccgcttgtt cagcattgat ggattcaatg
   101521 accagcaccg ctgcttgtgt ttcttccgtc agcatcgttc tttgggcttc acgccagttg
   101581 agacagcgac agatcgctcc ttgttcatca tagtagatga tttcttccgg aagtgccgga
   101641 gcatcggaat ctgcacctaa aggcaggaat gattcgccac cttgggcttt tcctaaatgc
   101701 agatttcctg cgatcttttc gatatcttct ccgccgcaag gtacgccaaa agacaaggaa
   101761 atactattat agatatctac aagcggattg attgggaaaa attcccgttc ttgatttgca
   101821 cgtttcagta aagcttcaat agaagaacgt gcaccttttt tagtcttgaa tgtggtaaat
   101881 gcctgacgcc actgagcaat gacttcgttt tggctgaatg tttcttctgt aaggtaattt
   101941 cttgcttctt ttgctgcctc attcaataat tgatgatacg tttcttcact ttcttttgtt
   102001 acgtggttat cgataccatt tacggataag atttcgatgg ttgcttcagg aaatacttcc
   102061 cagaaattgg tatccactat tacttttttc atctgttcac acctcttgat tagaataatt
   102121 gcttgatgaa tagatagtct gtttggggat catctcccat ataaaaaaca tgttcgctgt
   102181 atttgataaa tcctttttta cgataaaaag cgagcgcaac atcgttgtgt tcccaaacac
   102241 cgagccaaat ggctgttttt tgcttttctt ttgctttttc aatagctgta tctagtaaaa
   102301 atgtaccgat accttgatgt ttaaattttt ttcgtacata gattcgctcg atttctaaaa
   102361 aatgatcagc catttcctca gattgactcg ttcctgtatt tagtttcagg taacccgcag
   102421 gctcttgatc gatactcact aggaaaaaat cggtttcttt atcttttagc tcttctgtaa
   102481 gtttttctag tgcataagct tgtgtcaagt aatcagctaa atgctccggt gaattatctt
   102541 ttccaaatgt atctgtaaat gtttcgatac taatttgttg tagtaagtct acatctgaag
   102601 gcgtcatttt tcgaatttcg tatttattca cggcttcttc ctttcaatag atccttttat
   102661 tgcctttttt gacaaaattc caatcttcgc taacattctt gcatacttta tttaaaagat
   102721 attccaattg ttttgcttct tcgtcagaaa gaccatttaa tgcgactgca ttggagtagt
   102781 tgttttctcg aatgatgaaa ggatagattt ctgctccttt tttagtcgga tagagtttct
   102841 tgattttttt attttcttta tcttccaaac gttcgatcat cccattggat tctaatttct
   102901 tgattgctcg ggcagtcgtt gtacgatcta ctttgatcat ttctgctagt ttttcttgga
   102961 tgattccagg attttcgcaa atacgtacta aataaagata ctgtcctctt gttaaatcga
   103021 cttctttgaa ttcgatattg ctaatagaat ctagcgctcg ggcaatcatt ccgatgtctc
   103081 gaaggatttc agccatttca tcccaccttt attttgtttg taagactagt tcacctcttt
   103141 ttgttgcaaa tgcaactatt ttcaataaaa aaatcaagtt cttttttaat aactagtaaa
   103201 gtatattctt ttcttctttt acgaaaaagc tcaatcacaa tagatctggt ttttgttttc
   103261 taaaataagt aactgtttct tcgttgttcg cttttctgat agctttggca actcttctat
   103321 actaaaaaat cccatgttgg aagtttcatt attctcaata aacttggcct cttcaccgtg
   103381 gatcgcacaa gcaaaaacaa gtttataata ctgaaaaagc tgtggaatat ctttttgttt
   103441 attcgtatca aaaactgctc gcaactgagt agtttctact gttaatcctg tttcttcata
   103501 gacttcttta cgcacatttt cttcaggaga caatcctatt tcagcaaatc caccaggaag
   103561 tgaccattct ttcgtccgtt tatcttcgat tagtaggacc ttgccatctt ttttgatata
   103621 ggcacgaaca tctacttttg gtgttggatg tccttctcca atcgttgtga gcgcttttat
   103681 ttcttcgaaa gtttcttttc ctatttcact gatcagttcc aatgaaatcg tccggatctc
   103741 ctcaaaacgc tctttatcaa atacatcttt tccataatat agaccagctt gagaaagtgc
   103801 gagtagtctt ttgtattgag ccaacttctt gttcattctc ttcccttctt ttttagcaaa
   103861 tgtatgacta tgtaatcaag tatagaagac tggtttaatt acggcaaata aatataatga
   103921 aatctgcaat aaataaaaga atgttaaaaa actcgagaac aaaagacatt cgacttctct
   103981 ggggctgtga ataaatggcg ttcaaaagct tgcatctgcg gtaataagcc ccaccaaacg
   104041 aaaaatatga cgagctattc ttgtctggct gttcttatta attgaggcag gacagctttt
   104101 tcacaacctc cccactaaac ggtgttctcc taccaactcc tcggtcacaa gtcacaatat
   104161 tcatcaaaca tgagaagctg tttttttgaa attgctcctt gtgactcgga gctgaacgac
   104221 aggctcacga cctctcggta aacagcgttc aaaagccaat ttttcgatat taagccattt
   104281 ctttgttact tattgtcatt gatttctttt tctaatttat ccaatagtgg agtgtaatcc
   104341 acttgagtat agtctgttac atcaaattca tatagtgttc ctaactggaa tttgtcatat
   104401 tttcggtcgg cgatgatctt tttgaatgct tctttcgtaa tatgattggt ccctttcgtt
   104461 cgatcttcca atacgtcacc atagtgataa tgatccatga tatagctcaa atgacgatct
   104521 gattcacgat cacgtttgta ccgacgttgc cataacactt caaagtctgc tgttaggcga
   104581 atcgtgatca cctgatatcc gtatctatct gctaattctt ggagtcgtgc tttttgctta
   104641 tcactaaaag gatactcgga cacaatcact ttctttcctg cttccatata caaatcaagt
   104701 gctttgtaat agaaaggata aactttcgtc ctttcttgtt ccgcccgttc ttccaaattg
   104761 ttaaacccga tggattctgc atagtattcc ttgatttcat cgagcgtgat ggcatacata
   104821 tctggaaatc gttcccgtag tttattcata agatatgttt ttcctgtacc aggactacca
   104881 gccagaagaa tgaaatactt tttcatctca tttatttcct aagttaattg gactttccaa
   104941 gttcataaac agtccaatct tatgcttgac aatttctttt actgcttcat ttgctggaat
   105001 cacattatgg cgaagagact tgttgatttc tgtttcacta aaggtttctt tagctacttt
   105061 cgtccagttg actaaaagct ccgttccaac attgaatttg cggatcccgt tattgatcaa
   105121 ttcaggataa tcttcttctt tcacacctgt tcctccatgg ataactaggg ggacatcaac
   105181 tactgcatcg atttctttca gcaagggaat gtttacttct gtttttgatt tgaattgtcc
   105241 atgattcgta ccgatagcaa tagctaatgc atccacgcct gtagcttcta caaatttcac
   105301 tgcgtcttcc ggtcttgtat ataccttgtc attttcagcg acatggattc cttcttctgt
   105361 accgccgatt gttccaagtt ctccttctac ggaaacaccg tgcgcatggg catattctac
   105421 tactgctttt gtcttcagga tattttcttt gaaaggcaga tgggacccat catacatgac
   105481 agaagtatat ccgctgtcga ttgcttcttt gatatcatca aagtctcggg cgtggtctaa
   105541 gtgcaagact gcatcaacca tttcttcttc tgcaatagct gtcattacat tgactaacac
   105601 atgcatgccg atatatttag cggtatcgac acttgtttga ataatgatcg gcgaacccat
   105661 ttcttttgct gcgcctagca tagcaggaag catttctagg ttatgcgtat taaaagctcc
   105721 aactgtaaaa ttcaactctt ctgctgtttt tgttacttct ttcaatgttg tatacatctt
   105781 ttattgccac cttatctttt tatttgtttc ctttgatcgt tacttgtttt gcaatttgtc
   105841 gcatctcatc cattttgccc atgtagtaat cgatcccttg atcatcacca gcacgagcag
   105901 catctgcacg cttctggtta tagaggctca tcagtttttt atacccatct ccgatcgtct
   105961 gtttattttc caaactcttt tctaaatatt ggatggcttg atcgttcaca tacaattcag
   106021 aaaatttaag tccaacttgt tcataaagtt tcgctaattt atgcttatct tgggtagtgg
   106081 aaatctcttg tttcaattgt gtaatctctg attgaatctt ttcggtcgct tctggcgata
   106141 gggctttttc ttcttttgcc agaacttttt tcggttcttt ttcttttttc ttaaaaaatc
   106201 caaacatcat tttccctact ttcaattaaa atgctttcaa aactgggctt aagatccagg
   106261 catataagag tgctgcggct actgtatcta catcggttgc tgtagcattg ttgaatccca
   106321 tcgaattaaa gatcgttact agcaaagcgg gcaataatgt aataaagaaa ccatgagcaa
   106381 taccgccaat gatcgctcct cggcgtccgc caactgcgtt gccaaatatc cctgctgtcc
   106441 ctccggcaaa gaaattggtt agcataccag gtaaaatcat cgctaagccg aacatgggca
   106501 aagtaaacat ggcaataatc gtaccaatcg ttgtcgtaat gaaacctaaa atgacagcat
   106561 ttgggctata aggaaagaaa actggacaat ctaaggcagg gatcgcatca ggaactaatt
   106621 tcatagctat ccctcgaaat gccggcacga tttcacctaa cagtagacgt acaccagcta
   106681 gcaatacata cacacccact acgaattgga tggcttgtaa aaaggcaaac atgatatagt
   106741 tttgatctcc tgataattca gaagcgaatg gttcgcctgc aaataaaaca gtgatgatat
   106801 atagcgggac catcacgacc atgacagaca aataagtatc ttgcagaaat tcgaaatgtg
   106861 tcggcaactt gatatcttcg atcgactttt tattttcgcc tttctcacca aaaagcttag
   106921 caacaccggc ttcaaataag tacccgatcg tacaaaaatg acctaaagca atatcatttg
   106981 atccagtgat tttacgaatg atcggttgcg ctactgccgg catagcaatg gcgaaacaag
   107041 ctccgataaa accaccgacc aagatcaata cgatccctcg cagaccggca aaatagccaa
   107101 agactgtcgt catcgttgcc atccataaaa ttgcttgacc agttaaaaaa atgtacttcc
   107161 attttgtgaa acgagccaaa ataatattga atacaaaaat ggctaagaac gtcagtgcaa
   107221 tatctctacc taaacccaaa tcattcattg cttgaccatt gatagattca atagaaggga
   107281 tgatcccttg catatgaaat ccttcagtaa agattttccc gaaataagtt aaacttccaa
   107341 cgatgatgct cgaaccggca ctcaacactt gaaatcctag gagtgtcttt aacgtgccag
   107401 agatgacttg tcctgctgat ttcttctgca gtagtagacc caacatagca atcaatgcaa
   107461 tggtgatcga tgcctgagtc aaaatatttt cgatgataaa attgataacg cccatgtt
//
LOCUS       DAKCAA010000002        97760 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000002 DAKCAA010000000
VERSION     DAKCAA010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 97760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 97760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.002"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            119..1243
                     /locus_tag="OUE31_000094"
     CDS             119..1243
                     /locus_tag="OUE31_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCU0221139.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            1470..2387
                     /locus_tag="OUE31_000095"
     CDS             1470..2387
                     /locus_tag="OUE31_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0221140.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            2380..3213
                     /locus_tag="OUE31_000096"
     CDS             2380..3213
                     /locus_tag="OUE31_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCU0221141.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            3296..4414
                     /locus_tag="OUE31_000097"
     CDS             3296..4414
                     /locus_tag="OUE31_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCU0221142.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            4408..6306
                     /locus_tag="OUE31_000098"
     CDS             4408..6306
                     /locus_tag="OUE31_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HCU0221143.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            6300..7523
                     /locus_tag="OUE31_000099"
     CDS             6300..7523
                     /locus_tag="OUE31_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCU0221144.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(7609..9543)
                     /locus_tag="OUE31_000100"
     CDS             complement(7609..9543)
                     /locus_tag="OUE31_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCU0221145.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            9769..10425
                     /locus_tag="OUE31_000101"
     CDS             9769..10425
                     /locus_tag="OUE31_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCU0221146.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(10499..10852)
                     /locus_tag="OUE31_000102"
     CDS             complement(10499..10852)
                     /locus_tag="OUE31_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCU0221147.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            11044..11973
                     /locus_tag="OUE31_000103"
     CDS             11044..11973
                     /locus_tag="OUE31_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCU0221148.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            11984..12820
                     /locus_tag="OUE31_000104"
     CDS             11984..12820
                     /locus_tag="OUE31_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HCU0221149.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            13068..13844
                     /locus_tag="OUE31_000105"
     CDS             13068..13844
                     /locus_tag="OUE31_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0221150.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            14020..14763
                     /locus_tag="OUE31_000106"
     CDS             14020..14763
                     /locus_tag="OUE31_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0221151.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            14756..16336
                     /locus_tag="OUE31_000107"
     CDS             14756..16336
                     /locus_tag="OUE31_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HCU0221152.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(16587..17066)
                     /locus_tag="OUE31_000108"
     CDS             complement(16587..17066)
                     /locus_tag="OUE31_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCU0221153.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(17082..17834)
                     /locus_tag="OUE31_000109"
     CDS             complement(17082..17834)
                     /locus_tag="OUE31_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCU0221154.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            17951..18021
                     /locus_tag="OUE31_000110"
     tRNA            17951..18021
                     /locus_tag="OUE31_000110"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17983..17985,aa:Gly,seq:ccc)
     gene            18382..19107
                     /locus_tag="OUE31_000111"
     CDS             18382..19107
                     /locus_tag="OUE31_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HCU0221155.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            19362..19628
                     /locus_tag="OUE31_000112"
     CDS             19362..19628
                     /locus_tag="OUE31_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HCU0221156.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            19625..20056
                     /gene="ruvX"
                     /locus_tag="OUE31_000113"
     CDS             19625..20056
                     /gene="ruvX"
                     /locus_tag="OUE31_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HCU0221157.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            20081..20386
                     /locus_tag="OUE31_000114"
     CDS             20081..20386
                     /locus_tag="OUE31_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HCU0221158.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(20467..21612)
                     /locus_tag="OUE31_000115"
     CDS             complement(20467..21612)
                     /locus_tag="OUE31_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCU0221159.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(21673..22320)
                     /locus_tag="OUE31_000116"
     CDS             complement(21673..22320)
                     /locus_tag="OUE31_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0221160.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            22514..22807
                     /locus_tag="OUE31_000117"
     CDS             22514..22807
                     /locus_tag="OUE31_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221161.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            22851..23162
                     /locus_tag="OUE31_000118"
     CDS             22851..23162
                     /locus_tag="OUE31_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221162.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            23159..23783
                     /locus_tag="OUE31_000119"
                     /pseudo
     CDS             23159..23783
                     /locus_tag="OUE31_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            23924..24082
                     /locus_tag="OUE31_000120"
     CDS             23924..24082
                     /locus_tag="OUE31_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221163.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            24083..24445
                     /locus_tag="OUE31_000121"
     CDS             24083..24445
                     /locus_tag="OUE31_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221164.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            24482..25330
                     /locus_tag="OUE31_000122"
     CDS             24482..25330
                     /locus_tag="OUE31_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HCU0221165.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            25320..26795
                     /locus_tag="OUE31_000123"
     CDS             25320..26795
                     /locus_tag="OUE31_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HCU0221166.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            27061..27468
                     /locus_tag="OUE31_000124"
     CDS             27061..27468
                     /locus_tag="OUE31_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HCU0221167.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            27471..27686
                     /locus_tag="OUE31_000125"
     CDS             27471..27686
                     /locus_tag="OUE31_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221168.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            27690..28070
                     /locus_tag="OUE31_000126"
     CDS             27690..28070
                     /locus_tag="OUE31_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCU0221169.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            28204..28359
                     /locus_tag="OUE31_000127"
     CDS             28204..28359
                     /locus_tag="OUE31_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HCU0221170.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            28428..28901
                     /locus_tag="OUE31_000128"
     CDS             28428..28901
                     /locus_tag="OUE31_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HCU0221171.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            28898..30592
                     /locus_tag="OUE31_000129"
     CDS             28898..30592
                     /locus_tag="OUE31_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCU0221172.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            30558..30743
                     /locus_tag="OUE31_000130"
     CDS             30558..30743
                     /locus_tag="OUE31_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221173.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            30747..31922
                     /locus_tag="OUE31_000131"
     CDS             30747..31922
                     /locus_tag="OUE31_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCU0221174.1"
                     /translation="MAFFKERQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            31915..33438
                     /locus_tag="OUE31_000132"
     CDS             31915..33438
                     /locus_tag="OUE31_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCU0221175.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            33494..33778
                     /locus_tag="OUE31_000133"
     CDS             33494..33778
                     /locus_tag="OUE31_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HCU0221176.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            33765..34100
                     /locus_tag="OUE31_000134"
     CDS             33765..34100
                     /locus_tag="OUE31_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HCU0221177.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            34395..35021
                     /locus_tag="OUE31_000135"
     CDS             34395..35021
                     /locus_tag="OUE31_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221178.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            35763..36599
                     /locus_tag="OUE31_000136"
     CDS             35763..36599
                     /locus_tag="OUE31_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCU0221179.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            36664..37098
                     /locus_tag="OUE31_000137"
     CDS             36664..37098
                     /locus_tag="OUE31_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0221180.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(37166..38488)
                     /locus_tag="OUE31_000138"
     CDS             complement(37166..38488)
                     /locus_tag="OUE31_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HCU0221181.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(38642..40282)
                     /locus_tag="OUE31_000139"
     CDS             complement(38642..40282)
                     /locus_tag="OUE31_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HCU0221182.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            40612..41082
                     /locus_tag="OUE31_000140"
     CDS             40612..41082
                     /locus_tag="OUE31_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HCU0221183.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            41465..42568
                     /locus_tag="OUE31_000141"
     CDS             41465..42568
                     /locus_tag="OUE31_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCU0221184.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            42852..43532
                     /locus_tag="OUE31_000142"
     CDS             42852..43532
                     /locus_tag="OUE31_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCU0221185.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            43622..44656
                     /locus_tag="OUE31_000143"
     CDS             43622..44656
                     /locus_tag="OUE31_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCU0221186.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            44670..45005
                     /locus_tag="OUE31_000144"
     CDS             44670..45005
                     /locus_tag="OUE31_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221187.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            44989..47469
                     /locus_tag="OUE31_000145"
     CDS             44989..47469
                     /locus_tag="OUE31_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221188.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            47525..49084
                     /locus_tag="OUE31_000146"
     CDS             47525..49084
                     /locus_tag="OUE31_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0221189.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            49081..50445
                     /locus_tag="OUE31_000147"
     CDS             49081..50445
                     /locus_tag="OUE31_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCU0221190.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            50616..51686
                     /locus_tag="OUE31_000148"
     CDS             50616..51686
                     /locus_tag="OUE31_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0221191.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            51701..52369
                     /locus_tag="OUE31_000149"
     CDS             51701..52369
                     /locus_tag="OUE31_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0221192.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            52389..52967
                     /locus_tag="OUE31_000150"
     CDS             52389..52967
                     /locus_tag="OUE31_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCU0221193.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            53370..54281
                     /locus_tag="OUE31_000151"
     CDS             53370..54281
                     /locus_tag="OUE31_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCU0221194.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(54537..55454)
                     /locus_tag="OUE31_000152"
     CDS             complement(54537..55454)
                     /locus_tag="OUE31_000152"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HCU0221195.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            55656..56093
                     /gene="zapA"
                     /locus_tag="OUE31_000153"
     CDS             55656..56093
                     /gene="zapA"
                     /locus_tag="OUE31_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HCU0221196.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            56151..56699
                     /locus_tag="OUE31_000154"
     CDS             56151..56699
                     /locus_tag="OUE31_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HCU0221197.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            56814..59174
                     /locus_tag="OUE31_000155"
     CDS             56814..59174
                     /locus_tag="OUE31_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HCU0221198.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            59261..59575
                     /gene="trxA"
                     /locus_tag="OUE31_000156"
     CDS             59261..59575
                     /gene="trxA"
                     /locus_tag="OUE31_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HCU0221199.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            59757..61535
                     /gene="uvrC"
                     /locus_tag="OUE31_000157"
     CDS             59757..61535
                     /gene="uvrC"
                     /locus_tag="OUE31_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HCU0221200.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            61680..62579
                     /locus_tag="OUE31_000158"
     CDS             61680..62579
                     /locus_tag="OUE31_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0221201.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            62572..63834
                     /locus_tag="OUE31_000159"
     CDS             62572..63834
                     /locus_tag="OUE31_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0221202.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            63997..65895
                     /locus_tag="OUE31_000160"
     CDS             63997..65895
                     /locus_tag="OUE31_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HCU0221203.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(66194..66913)
                     /locus_tag="OUE31_000161"
     CDS             complement(66194..66913)
                     /locus_tag="OUE31_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HCU0221204.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            67250..67582
                     /locus_tag="OUE31_000162"
     CDS             67250..67582
                     /locus_tag="OUE31_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221205.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            67569..69572
                     /locus_tag="OUE31_000163"
     CDS             67569..69572
                     /locus_tag="OUE31_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HCU0221206.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            69591..70061
                     /locus_tag="OUE31_000164"
     CDS             69591..70061
                     /locus_tag="OUE31_000164"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HCU0221207.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            70082..70666
                     /locus_tag="OUE31_000165"
     CDS             70082..70666
                     /locus_tag="OUE31_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HCU0221208.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            70681..71667
                     /locus_tag="OUE31_000166"
     CDS             70681..71667
                     /locus_tag="OUE31_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HCU0221209.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            71657..71968
                     /locus_tag="OUE31_000167"
     CDS             71657..71968
                     /locus_tag="OUE31_000167"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HCU0221210.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            71990..73771
                     /locus_tag="OUE31_000168"
     CDS             71990..73771
                     /locus_tag="OUE31_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HCU0221211.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            73764..75140
                     /locus_tag="OUE31_000169"
     CDS             73764..75140
                     /locus_tag="OUE31_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HCU0221212.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            75147..75782
                     /locus_tag="OUE31_000170"
     CDS             75147..75782
                     /locus_tag="OUE31_000170"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HCU0221213.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            75812..77167
                     /locus_tag="OUE31_000171"
     CDS             75812..77167
                     /locus_tag="OUE31_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HCU0221214.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(77359..78753)
                     /locus_tag="OUE31_000172"
     CDS             complement(77359..78753)
                     /locus_tag="OUE31_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCU0221215.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            78845..79816
                     /locus_tag="OUE31_000173"
     CDS             78845..79816
                     /locus_tag="OUE31_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HCU0221216.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            79813..80595
                     /locus_tag="OUE31_000174"
     CDS             79813..80595
                     /locus_tag="OUE31_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HCU0221217.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(80764..81135)
                     /locus_tag="OUE31_000175"
     CDS             complement(80764..81135)
                     /locus_tag="OUE31_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCU0221218.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            81269..81712
                     /locus_tag="OUE31_000176"
     CDS             81269..81712
                     /locus_tag="OUE31_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HCU0221219.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(81755..82564)
                     /gene="yidA"
                     /locus_tag="OUE31_000177"
     CDS             complement(81755..82564)
                     /gene="yidA"
                     /locus_tag="OUE31_000177"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HCU0221220.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(82583..83950)
                     /locus_tag="OUE31_000178"
     CDS             complement(82583..83950)
                     /locus_tag="OUE31_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCU0221221.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(83934..84764)
                     /locus_tag="OUE31_000179"
     CDS             complement(83934..84764)
                     /locus_tag="OUE31_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HCU0221222.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            84927..85364
                     /locus_tag="OUE31_000180"
     CDS             84927..85364
                     /locus_tag="OUE31_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HCU0221223.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            85440..86060
                     /locus_tag="OUE31_000181"
     CDS             85440..86060
                     /locus_tag="OUE31_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HCU0221224.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            86249..86755
                     /locus_tag="OUE31_000182"
     CDS             86249..86755
                     /locus_tag="OUE31_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HCU0221225.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            86772..87671
                     /locus_tag="OUE31_000183"
     CDS             86772..87671
                     /locus_tag="OUE31_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HCU0221226.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            87758..88642
                     /locus_tag="OUE31_000184"
     CDS             87758..88642
                     /locus_tag="OUE31_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCU0221227.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNYTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(88834..88905)
                     /locus_tag="OUE31_000185"
     tRNA            complement(88834..88905)
                     /locus_tag="OUE31_000185"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(88870..88872),aa:Arg,seq:ccg)
     gene            88965..90299
                     /gene="rpoN"
                     /locus_tag="OUE31_000186"
     CDS             88965..90299
                     /gene="rpoN"
                     /locus_tag="OUE31_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HCU0221228.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            90448..91539
                     /locus_tag="OUE31_000187"
     CDS             90448..91539
                     /locus_tag="OUE31_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HCU0221229.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            91580..92581
                     /gene="gap"
                     /locus_tag="OUE31_000188"
     CDS             91580..92581
                     /gene="gap"
                     /locus_tag="OUE31_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCU0221230.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            92691..93881
                     /locus_tag="OUE31_000189"
     CDS             92691..93881
                     /locus_tag="OUE31_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HCU0221231.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            93985..94740
                     /locus_tag="OUE31_000190"
     CDS             93985..94740
                     /locus_tag="OUE31_000190"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCU0221232.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            94856..96154
                     /gene="eno"
                     /locus_tag="OUE31_000191"
     CDS             94856..96154
                     /gene="eno"
                     /locus_tag="OUE31_000191"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HCU0221233.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            96553..97692
                     /locus_tag="OUE31_000192"
     CDS             96553..97692
                     /locus_tag="OUE31_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HCU0221234.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        32476 a        16706 c        20267 g        28311 t
ORIGIN      
        1 aaaagccaaa acgacaagta aaatattttt ttatataaat atttgtgtta ctaattccgt
       61 taatatacat aagtgaaagc gttttatata agaacttgaa aagaaagaag ggatagacat
      121 gaaaaaaaga tacaaattgg tgatagcttt gctaaacatt accctattat tcagcttaag
      181 tgcatgtgga aaaactaacg aagaagtaac agcaaacatc gcagatccaa tgataaaaaa
      241 agccactaca ttagaagtat atgtcgcaaa cggcaaactg acaaactatg ttgaaaatgc
      301 tgcaaaaatc tataaccgca aaactggagc aaatattgac ttaaaaattg tgaatgtagc
      361 ttcgggaaca gcaacagtac aaatgatcac cccaaaattg gtaacacacg aagatatgcc
      421 ggatattatc tccatggcag acacttcagc agcaggtgtg ctggaaaaat ttcaagatgc
      481 tttttatagt gctgatgaat atggatttta tgacaaatat ggcgatcagt tttatgatca
      541 aaaattgaat attttgcgtc aacaaacgag taatgaaacg attattcctt gggctagtga
      601 ttttacccca gcactttgtt attatcaacc aaaaaaattt gctgaaatag gtgtagattt
      661 tgaagaaatc agttcttggg aagaatatat ccaggtggca aaagcattaa aagaaaaaac
      721 tggtagtttt ggaattgcct tgccagaatc tggggaccaa gaattgttta tcaacatgct
      781 agcccagcag aatcaatctt tgcttgatga agaaggaaat atccgtctga atactaaaga
      841 agcgaaacat gctgcaaagt taatcaaaga aatgatcgac tcagatattg tacatttcta
      901 cggtgcacaa gatgctgaga aagcatttca agaatctgca atgtttgttg ctggcggctg
      961 gtatgctacg aatatgtctt tgaattttcc tgatgcatct gacaaatggc gcatggctcc
     1021 actgattcct ttttcaaaag aaaatccagg aaaaggtgca gtatcaggag gatcaagttt
     1081 ttatgtccct aaagatgcca aaaatccaca agtggcacaa caatttctta catttatgct
     1141 gacagatgaa gaatgcttag ccaacgcact ggagctgggc gtggctacat ctaactcatt
     1201 ggcctatcaa acagaagcag ctgagaaaaa gtttgactac taaggaggac aaaaatacta
     1261 tgaactattg aataaaatca atgaaaatac atcaaatact gttttaccag ccacttattc
     1321 agatgctacg tcttatttga ctaccgctgc atataactat tggcaaacag gtgattttga
     1381 aaattcatat ctaaaagaag cagaaaattt tgctcataag tacggcgtaa aattaactgg
     1441 tgattaaaaa atattaggag gacttaacga tgatgcaatc ttcgttacca agcaagacaa
     1501 taaagaacag caagaaaaaa gcaacagata cgtctcataa aaaaagtgct tatggattgg
     1561 tcacaccttt tgttattttc tttattgtga cgattttgat tcccatcatt atctcgtttg
     1621 cttttagttt tatgaaaatt ggctactcat ttgaatttgt tggatttgac aattatctag
     1681 ctatcttccg agatccattg tttattaaat cttacacgaa tgttttgatt atcatggcag
     1741 gatcaattcc aataacgatg ctattagcta tttactttgc tgttttattg aattcagcac
     1801 agttaaaagg aaaaggattt tttagaactg tctattatat tccaaccatt acatcaacgg
     1861 tggctgtagc ttccgtattc atgacttttt tcaatccgac tgggttattc aatggatttt
     1921 tgaatgcgct aggaattaac ggtgtacagt ggttaacaaa tcctttttgg atacgaatat
     1981 caatgatcat cacgatgatt tggcttagtg taggatataa cactatttta tttttagctg
     2041 gtcttcaagg gatttctaaa gagatatacg aaagtgctga aatagatgga gcatcgaaat
     2101 ttcggcaatt ctttttatta acgatcccca tgctaaagcc aatcatttta atggccacag
     2161 ttttagccac tatcaatggc ttgggtaatt tcaatatccc aaatatattc tttgggactt
     2221 ccaatggacc agaaaattca gctttggtcg taggagtcaa tttatataaa acaagttttg
     2281 aaatggttga ttttggaaaa gcctctgcta ttgcctggac gatggtgttt gtatctgtta
     2341 tattatcggc tattcaattt aaattcggag gtgataaaaa tgactaaaca aaagatacaa
     2401 agcagaattt ttacgtacgt cattattgtg tttggtgcct taatattttt gatgccatat
     2461 ttatatatga ttgtagcttc aacgcaaagt aatcaagaaa ttttaagtgg cggaatcaat
     2521 ttcaagtttg gggatatgct attaaaaaac tggcaagcca tcatggcgag atataattat
     2581 cccttgatta tttggaattc gattgttatt gctgtaatca gtacagtttt agctacagcc
     2641 agttctacaa tggcgggtta tgcattagca aagtatcgtt ttatggggaa taaactgttg
     2701 ttcaatacag ttatgctatc taggatggtg ccttttttta ccacattgat tcctttattt
     2761 tacattatga gtcgtttagg attatcgaat acttatgcag gtgtgatcat cccttcgatt
     2821 gccagtacaa cttcagtgtt tatgatgcga caatatagca gtcaatttcc tacagcactg
     2881 atggaggctg ccagaatcga tggtgccaat gagtgggtga tttttacgaa aatcgctgta
     2941 ccgattttat cacctacgat tattactagt ggtttactta tctttatggg aagttggaat
     3001 caatatctat ttccattagt catgctttca gataaagata aatatacggt tcccttaatt
     3061 atcaaaaata tgacggtttc tagtacaggt gagccaatta attatggcgc aattatgcta
     3121 attttagcaa cttcagtgat cccaatggtc ttgatttatg tgtgggcgca gtctaaattt
     3181 aaggagaatg acattggagc tgcaaataag taaaaaaaat aacgaatgtt aaccatctag
     3241 ttcgttctag gagcaactcc acattcataa aaattaaaag aatggcggga tatccatgaa
     3301 tgaacagacg aaggaatggt caagaaaaat tttgaatgta gcttctgaaa agatagatgc
     3361 ggaattagac agaatgggga ataaaattcc atatatttct tacaacggaa aatatacaga
     3421 cgtaataaag gacagaggaa tcgactggtg gaccaatggt ttttggagtg gtattttatg
     3481 gcagctcttt cacaagacaa aacgagaaaa gttcaaagag gcagcaatac aacaagaaca
     3541 attattagaa tctgccctgt accatttttc agacgttcat catgatgtag gttttttatt
     3601 cttaccatcg gctattgcac attatcaaca gtctcaaaac aaacatagtc gacaactagg
     3661 gttacatgca gctacggtac ttgctggacg ctataatatt tcagggaact atttagtagc
     3721 atggaatgac cataaacctg gttggatgat tattgatagt atgatgaatt taccattact
     3781 gtattgggct tcgagggaaa ctggtgatcc gaggttctct aaaattgctc ggcagcatgc
     3841 agatacaaca gctaagtatc tagtgaggaa agatggatca accgggcata tcgcagaatt
     3901 tgatgcagaa tcagggaaat atattcggtt acttggcggg caaggataca atgagaattc
     3961 ttgttggagc agaggaaatg catgggcttt atatggattc gcgttaagtt atcgttacac
     4021 aaaaaatccg tactatctag ctatagcaga aaagatagca gtaaatttta ttcagaaaat
     4081 cgaaaaaact ggttatattc ctctcattga ttttgctgta aaagattcga atattgatac
     4141 cagtgctgga gtatgcgctg catgcggtct tctggaatta gcaggatatg tttcctctgt
     4201 acgatcaaaa atgtatcatg aagctgctat caatatactc caaaagacag aaaagcacta
     4261 tgcaaattgg aatatggatg aagatgggat cattggaggc ggagcagaag cataccatag
     4321 agaactgact tataatgtgc cactgatcta ttctgattat ttttttattg aaggcttact
     4381 tcgattagaa cagtcggaat tagctatttg gtagtaaaaa gaggagaaaa tacaatgaaa
     4441 catccagtac cactattaag gaccagacag gattactttg acttatttaa aaagataaat
     4501 caaccactcc agccgtttta tcgagcaagt ggcgcacaaa ttgattatat acatcaaggg
     4561 gtaggatatg gaaataaaat tgcaggaatg gaaggattct ctcgggtttt atggggagcg
     4621 gggcccgcaa ttgaccaatt agatgaacga tggttgaaat taattctatc aggaataaaa
     4681 gctggaacag atccttccca tcccgattat tggggagaaa tacatgaaag agaccagcgt
     4741 atggtagaaa tgcccgcaat gttattagcg ttatatcatc atgaacaatt attatggaaa
     4801 aaattagata caggagaaaa aagccagatt attcattggt tctcgcaaat ttttgaatat
     4861 gaatgtgcag atggtaattg gcaatttttt aagataattg tcggaacaat tatccaaaaa
     4921 tttggttatc cagttaaaga atcagcactg aaagaagcat ttgataatat agaaaattgt
     4981 tatcttcaaa atggctggta tcgagacagt tcaagaggtc gccaagatta ttataatcct
     5041 tttgcatttc attattatgg tttgatttat agcgtactag aaccagaaaa gcccattagc
     5101 cagatatata agaaccgagc tattgatttt tctagagact atattcattt ttttgcggaa
     5161 gatggtgcaa atgtgccttt tggtcgaagc atgatttatc gttttgcagt ttcaagcttt
     5221 tggtcagcta tgttgtgggc cgatcttttg ccttttaaat taggtgaaat caaggggtta
     5281 gtcaatcgga atataagatg gtggatgcaa aaagaaatat ttgatgaaaa aggtatcctg
     5341 aatattggtt atacctaccc tcaattgaca ttgactgaac cctataatag tacgttatct
     5401 ccattatggc tgaataagat ttttttattg ttggcgctac ctgaagacca tgagtattgg
     5461 acggctaaag aaatgcctat gcctattcgt gaaggaacta aacttctttc agaagccaat
     5521 ttgctcatac aacatgataa tggacataca ttttttttga atgcgggaca attagggcca
     5581 aatttccata cattgaccaa tgaaaaatat ttaaaatttg cttattctag tcaatttggt
     5641 ttttcgatac cgcgagcgaa tcaattgaaa gcagaaatgg caatggattc aatgctaggg
     5701 attcagcgag cggacacata tatcacgacc agttttaaga atgagagcat caaaacctat
     5761 ggacagttca tcgttcgaaa taatgtacga gacattgtat gtaagaaaga ggtacttgcc
     5821 tctacatggg aacctacttt acaggcaaaa atcagaactt ggcttattcc ttttgaaggc
     5881 tggcagattc gcgtacacaa agtagaatta gatacagaat atgttctata tgagacaggg
     5941 tttgctattg aatgttctcc tgagaaagaa ggaataatca tagaagaaga caaggaaaac
     6001 tatagggtga gtgaagctgg cttttcaggt attatctgtt taagtgacga tactattaaa
     6061 cgaaaatcca cagctattat gggtttgccc aatacaaact tgatgacatg ggaaaacact
     6121 tttattcctg gattagaggg tacatttgga aaaggaaccc attggctcgg aacaggagtg
     6181 gttgctcatc aagatcggga ttatagttta gaagtatgga acaatcgtcc caaaattgat
     6241 tttgatggga caaccgggct aactatccaa aataaaaaca ataaaaaaag actaaaatta
     6301 tgctaaaggc tggtggggaa atgcttgata aagtgatgtt tgaagagata atacatccag
     6361 aaaaatggat aaatgaatgt tataaagaat taatggaaaa agaatggaat aatgagatcg
     6421 agcgttgtcg cagacacacg gagaggttaa tcaaacgtat cagtaacagt cagtatcaat
     6481 tcccaagcga gtgtcctata aaaggacgtt atccattaag agacaatatt ggttggacag
     6541 aaggattttg gacaggaatt aattggttgt tatttgagaa gacgggtgat cctttatttc
     6601 aacaaacagc tgaaaaagca gatatagatt ttatccacag gattgactgt caaattatca
     6661 ctaatcatca cgatcttggt tttttgtatt ctttatcaac cgtagcagat tataaaataa
     6721 cgggaaatcg aaaaatgaag gaagcttcaa ttgatgctgc agaaacatta cttcagcgtt
     6781 tttgggagaa ggcaggagtt atacaagctt ggggagatcc tagtgatcct tcacaacaag
     6841 gtagaatgat catggattgt tgcatgaatc ttccattatt gtattgggcg agtgaagaaa
     6901 ctggaaatca aaaatataaa aaagctgctc aggctcatat tcaaaatgca gcagattatt
     6961 tagtaagaga agatggttca acttatcata cattttatat ggatgtcaaa gatggaaaac
     7021 caagatatgg aagtacgcat caaggttata gtgataattc ctgttgggct agaggccaag
     7081 catgggggat ttacggtttt gcattaagtt atcgttattt gaaagaacaa aaatattttg
     7141 atttaagcaa aatattagcc aattatttta tgaatcggtt gccagaagat accatttgtt
     7201 attgggattt gatctttgat gattctagca gagaagaaaa agatacatct agtatggtga
     7261 tcatggtttg tggattatta gaattaatag aatcaggtct attagacaaa acagaaaaga
     7321 acttatacca gtctgctgtt tggaaaatta tgcgacaatt gaaagaaaga tatgctacaa
     7381 cggaagaaga agatggcttt ttaacacagt ctgtttataa taagcccaaa aataatgggg
     7441 taaatacacc ttgtatttgg ggtgattact attatttaga agctttagtg agaatgacta
     7501 gtaattggtc ttcttattgg tgaaaaaggt aaatatggaa tttttgtttg ataaaataaa
     7561 aaaagaaaaa ccaaaacagc atgaatggtt tctgttttgg ttttttcgtt aattttcata
     7621 ttcttctaat tccaagctta gttcttccca ttccgtcaat tttgtttctt gatcttgtct
     7681 agcagcttct aaatcttggt tcagctcatt gagttttacg tgatcttcca ggttttctgg
     7741 cgcgaccatt tcttgttcca actgatcgat ccattcatcg atccgcgcca tttcttcttc
     7801 aacctgagta atttttcgtt gaaggctacg gataagcttt tgctgttctt tgctttggta
     7861 ataatcagat ttgttcgtgg gagcaggagc agattctggc tcatcttgtg ccaacaattc
     7921 ggcgatttct tcttcttcct gctttttctc taaataataa tcatagtctc ctagatagac
     7981 tttgctgcca ttttcagaga gttcgacgac ttttgtcgcg atccgattga tgaaatatcg
     8041 gtcatgggaa acaaaaagca gtgtgccgtc ataatcgatc aatgcatttt ctaatacttc
     8101 tttgttgtca atatctaaat ggtttgttgg ttcatccaaa atcaaaaaat tttctttgtt
     8161 catcgctaac ttggctaaag caacccgtgc tttttcaccg ccacttagca gagggattgg
     8221 tttttctaca tcttcgccag aaaataagaa agcacctaaa gcacttcgga tctctttttc
     8281 tggagtggta ggatgctcat cccacaattc tgctaggatc gtcttgtttg tatgcagatc
     8341 agcttgacct tgatcgtaat agccgatggt gacatttgtc cctagcgttt cttttccacg
     8401 gataaaaggg atctggtgaa tgattgattt cagcaacgtc gatttcccga taccattcgg
     8461 acctactaga gcaatcgctt cttgacgacg gatatctaga ttgattggtt cagataaggt
     8521 gacattatca tatccgatag cggcatcttc gatttgcaag actacatttc cagaaggctt
     8581 ttctatactg aatagaaagt ttgcttgttt ttcatcccct tgaggacgat ccagccggtc
     8641 cattttttct aatgtctttc tgcggctttg cgctcgtttt gtggtagagg cgcgaacaag
     8701 gttccgagca acgaagtctt ctaatttatg gatttctgtt tgctgctttt cataagcctt
     8761 ccattcactt gctaactgtt ctgctttcaa atctagatat ttcgaatagt tacctttgta
     8821 atggcgcatt tttcttctgc ttaattcata gacttcattg actactttat ctaaaaaata
     8881 acggtcatgg gaaacaatca ataatgcacc agtatagctt tgcagataat tctcaagcca
     8941 ggaaagtgtc tcgatatcta aatggttcgt tggttcatct agaatcaaaa tgtcagggtg
     9001 ttgcaaaagc atgcgagcta aagctaaacg tgtgcgctgt ccgcctgata aagtatcgat
     9061 tttctgatca taaaatgaag aatcgaattt aaacccatgc aatacggaac gaatttcatt
     9121 ttcataacca tagccgtttc gatctgaaaa atcgtgttgc agccggtcgt attcttttaa
     9181 ataagaacta taagcaggtg tgtctggcgt accttcgcta atgaaaatct ctagctcgcg
     9241 catccgctct tccatttgtc taacttgttc aaaagctttc agcatctcgt tccaaactgt
     9301 ttcattggaa tcaagtcctg tgtcctgagc gaggtatccg agagtcgctg ttttattttt
     9361 agcgatcttt ccttcatcag gtgcttcaat tccagcaatg atctttaata aagtcgattt
     9421 tccagcgcca tttctgccaa ctaaagcgac acgagcgcct gtactgattt ctaaatgtat
     9481 gttttcaaat aagacttctg caccaaaatg gcgagcaatc tgattggctt gtaataatat
     9541 catggaatcc tcttttctac tttgtgaatt ctcctcaaat aaaaaactat ttttcaatta
     9601 gtagtctacc ataaattcca ttatactgcg agatttgcag aaatgataaa taaatgaata
     9661 aagaataaaa tttcacaata tctgagcaat ggaattgatt ttttcctata aatactgcta
     9721 tgatggagaa atcaaagatg taattagaca atacgtggag gtcatttcgt gaaagatcat
     9781 attattccaa aggcgacagc taaaagactg cctttgtatt atcgctattt aaggatttta
     9841 aataatgctg gaaagaaaaa agtgtcttca actgaattaa gtgaagccgt tcaagtagat
     9901 agtgcaacga tccgtcgaga tttttcttat tttggcgaat taggaaaacg tgggtatggt
     9961 tatgatgtag aagatcttat gcactttttt gcaaagacat taaacgacga tcaattgaca
    10021 aatgttgcgc tgatcggtgt agggaacttg ggaagtgctt tactaaaata caaattccat
    10081 caaagtaata gcatacgtat cagttgtgct tttgatgtga atgaggaaat cgttgggcgc
    10141 atcgtagacg gtatccccgt ttatccaatg gaagatatgt cagaacaaat caagatccaa
    10201 caaatcgaag tagcaatttt aacgataccc gctgaaagag cacaagaagt agtcaatcag
    10261 ttaacggaag caggaatcaa aggaatcttg aactttaccg ctgctcgatt gaatgctccg
    10321 tcagatgtat tgatccaaaa tgttgatttg acgaatgaat tgcaaacctt gatctatttc
    10381 ttgcattctg acgcaaatgc gcattccgaa aatacagcag aataaaaata aaaagcgatt
    10441 gaacaaatga aggcaaaact ttcacttgtt caatcgcttt tttctgtttg gacaacgatt
    10501 attttgttcg gaagatttct tcataagaaa gggaatcatc ttctgctgtc agttcatcta
    10561 gtagataacg gattttttta aagtcgatga accgtgcttg ccgaaagact tcttttcctt
    10621 gatgaaaaat caggacaact ggcgcagtca gcacttcaaa tttactagct acttctggtg
    10681 tttcaaatgc atccaaatga agtgccggaa tatcataatg tgtgagaagt tcctctagtc
    10741 gtggacgaac agcgtgacaa acactgcaat taggcatcga aagataaatg acggcaacgg
    10801 atgactgttg cagtatgtct tgaacttcag tcaagttagt ggtttgtttc atttttattc
    10861 tcccttttat gatagaagtg atatgtatga gaccttaatt taatgggaat aacagaaaaa
    10921 gtcaattgaa gtgctttggt aaaaaataag agttgtgtaa aaatttacag agcaacttgt
    10981 tttttttgaa taaaagcgta tatttgcaaa gcgaatgaac tagaaataaa aaggaggaaa
    11041 ctcatgtttt cttttattcc aaattcggtt ttgcagatga gtacgatttt cttatcgatc
    11101 gttattgaag cattaccttt cgtattatta ggctgtctta tctcaggcgc cttacaagta
    11161 tttttgaccc cagaacgtgt gaagagatgg cttcctgaaa atcgtatctt ctctattttt
    11221 actggttcga tcttaggatt tttctttcct tcatgtgaat gcggcatcgt accgatcgtt
    11281 catcaatttg ttaaaaaagg cgtaccagtt cacacagcgt ttgcttttat gctgactgct
    11341 ccgatcatca atccaatcgt gattttttcc acttttatcg catttggcaa ttcttggcag
    11401 atggcaagct ggcgggtgat aggcagcttt tttgttgccc ttgtgattgg tgtctggctt
    11461 gcctattttc aaaaagacgc tgtattgaaa gaaaaaatca cgtctaaagt agcagaaaat
    11521 caccatcatc atgtccatga agaagaacaa agtgagaaga atgaaccaaa aaatcagctg
    11581 atccatcaaa ctgggcatgt gttgacacat tcaatcgacg aattttttga tacaggtcgt
    11641 tatttgatca ttggcggatt aatcgcagct gcgatgcaga cttatttacc aactagaatt
    11701 atgctaacgc tcggctcaac aaagatttta gccattatca tcatgctgtt attggccttt
    11761 acgatgtctc tttgctcaga agcagatgcg tttataggat cttctttgtt aagtctgttc
    11821 ggcacagcac ctgtagctgc ctttttggtc tttggcccaa tggtcgatat caaaaatcta
    11881 ctgatgatga aacgatattt tacaggacgc tttattttat cgctgatcgg actgattgcc
    11941 cttagcgtta ttggattcac attatttatt taggagggaa aatatgctgc ggtttttgat
    12001 tttatctggg tatttcgaat tgatgatgta cttgcaagtt tctggcaaac tcgatcaata
    12061 tatcaatgtc cattatcgct acttagctat tctttcaatg attttatctg ctcttttggc
    12121 tttagttcag ctgtatttgt gggtcaaaaa cggaaaagca gaagaaaagg cacacgagca
    12181 cgatcatgac catgggttgt caaaacctta tcaacgtgga atcgcttatg tactgctagc
    12241 tttgccagta atcgtgggga cgttgtttcc aacagttagt ctcgacacta cgatcgtaga
    12301 agccaaagga tttaatttcc cagtaagtaa agaatcagta ggggatccgg agatgcagac
    12361 acaatactta aagccggata ccagtattta tttcaacaaa tcagactact tagaccaaat
    12421 gaatgagttg aaagaaaagt atggggataa gcaaactatc aagatcacag atgaaaacta
    12481 tttagaagtt atggagctaa tttataatta ccctagcgaa ttcattggca aaaaaatcag
    12541 ctatgaagga tttgtttacc aaacaccgaa cgatagcaat acagatatct tcttgttccg
    12601 attcggcatt atccattgtg tggcagattc aggagtcttt ggtttgttga cgcatatgcc
    12661 ggaaggagta acggttaaaa atgatgaatg gtataaaata gaaggaacca tccaatcaga
    12721 ctattatcaa ccattcaagc gtgaaatccc atctgtagtt gttacaaacg ctgagaaagt
    12781 ctctgctccg aaaaatcagt atgtgtatcg ttctttttaa aagaacaaaa taaataaaca
    12841 tagctcagac agctgacacg caaggacgtc ggttgtctgg ctttttttgc atgatgtatt
    12901 catttgtttg atatttattt tagaagcagc atcctgaaag tatttgatat cggtttcaaa
    12961 ggtgttggaa aagattgtga agagaattac aatttattcc taacatgtat gttgaaaagt
    13021 tgtatgaaat gattttgata gtaaaatatc gagtggaggt actttttatg gtaacgcgta
    13081 tatttatttt ggatgatagt ttggtttttg aaaaaatgct agtagaaatt ttggaagaat
    13141 ccagaatttt attaagtcct tggaaatttg agatcgttca gggattgaac gttatacaat
    13201 ttgttgaatt cattaaaaat aatgaaatct attcctcaga tatttttttc ctagacatcg
    13261 atttgaacgc ctattatagc ggtatcgaac taggcgaaat gcttagagaa aagaatgaaa
    13321 agtgtaaaat tgtttatcta acgtctcatc cgaataaagc aataactgtt attaatcgaa
    13381 agattacgcc tagtggttat ttgataaaag aattcactta tgaaaaaaat aaaaaaagca
    13441 tccaaagtta cttattgaaa gaaaaagaaa actatcctgt tcaacatgct acgaaaaaaa
    13501 ggtggacaac tgtccgttat ggtaatagcg atcactatat ccattacgat gaaatccttt
    13561 atctaatgag catgccaggt tataaaaata aaataggcct agtattgaaa gatgaagaga
    13621 ttctcgtaaa cggcacaatt aaaaaatata aaaaatcact cgaatatgag tatttatgta
    13681 aagatttaaa agcttatatc attaatactg aaaacattac atctattagc agagtaaacg
    13741 aaatagtaac atttgcaaat ggagaacaac tagagatggg aaagagaagt attgataaac
    13801 taaagaattt tatgcaagaa aagatagaaa atgaatcatt ttaaagaaaa caaagactca
    13861 tatcttacct gttagaagag tgttttcctg tagaagagaa caacccaagt agcagcctag
    13921 tcgtttctat ccttttttgt tatgcactct ttttgacatt tactccacca ataacgaagg
    13981 gtacaataaa aagtaataac aaacaaaagg agtacagaaa tgattgaatt catcaatgtg
    14041 agtaaaagtt acgggaaaaa acaagcatta aaagacttgt ctctctcgat aagacaaggg
    14101 gaaatttttg gatttttagg acataatggt gccggaaaat caactacgat taaaagttta
    14161 gttagtatta ttgaaccatc atcgggaacg attttagtag atggaatgaa attgacggaa
    14221 aatcgattga gtatcaaaca aaaaatcggt tatgtgcctg attccccaga tattttttta
    14281 caattgacgg ctggagaata ttgggacttg atttcagctg cctatgaatt agacacacaa
    14341 aaaaaagaaa agcgtttagc agaattgaca gcgctttttg atatgtatag tcatcaaaat
    14401 gaaacaatcg caagtttttc acatggaatg cgtcaaaaaa cgattttgat cggcacgttg
    14461 ctgccagatc cagatatttg ggtattggat gaacctttgc aaggacttga tcctcaagca
    14521 gcatttgatt tgaaagaaat gatgaaggct catgccgcaa aaggaaaaac agtcattttt
    14581 tctacacatg tattggatac cgcacaacag ttatgcgata aactggctat tttgaagaaa
    14641 ggtgaattga tttatcaggg ggcagttagt gaattattga atggctcacc tgatgaaacg
    14701 ctagaaaaga tttatttgaa aatggctgga aggcaagcga caggagatgg accgtatgta
    14761 taagcgacaa ttattagaat taattcgagt taatctttta tatgttaatc cacagctcac
    14821 gaataaagca agagagaaag gaaaaaaggg aaagcgatta actatctatc ttttgtctca
    14881 aaatcttttt tcagggctga tttttttact gatttacgga tttgctatgt ttgctatgaa
    14941 ctttgttaaa ttgccaggtt tctttactta ttacgtggca ctttttggta tgttaggttt
    15001 aactcaaagt atatcagtca tttataatat cttttttgaa ggaaatgacc tgcaagtatt
    15061 tttgcctctg ccttttggac aagaacaggt tttttcagca aagattttgg tagttgcttt
    15121 gaccatcatt ccttttgttt ttccgcttct agtcatgttt attttaaccg gatggcgagc
    15181 tgatctaggg attttgctta ctatcattat ctcaatcctt ttgttttctc tatttttgat
    15241 tattcttttt tgtctggcta gtttgattgt ttttggtttg gctcgaacag cagtgtttaa
    15301 aaaacataga aaaacagttt ctagtatctt gcttggcagc tcgatgctga tcgcatttgc
    15361 tggaatcatg tggatgaatc atcaaacggg gactattgaa aatgagttaa cagatcggca
    15421 tccgatttcg atattattgc cattctatga tgctgccagt cagccacttt ctcaacaagg
    15481 tttattgggt tggggaatac tagctatcac ggctctggga tttttccttg ctgtaaaaca
    15541 gctgatagta ccaaagctta cagagcaact gactgattca aacagtgagt tcaaaataaa
    15601 aagaacccat aaaaagaacc aaaatgtgca tcagctttta tttagttaca atgctcaatt
    15661 agtaaaagaa cctaatttga ttatgcaagt tctttcttct tccttgttaa ctccaatcat
    15721 ttttattctt gcttttgccc taggaggcga aataaaatta actgatttag ataataagtt
    15781 aatcggtgtt gttttcctgg tagggatcgc attggctttc ttaacagtta atcagacttc
    15841 ttttatcagc aatcttattt ctttggatca agaaaatttt ctgtttatcc gttctttgcc
    15901 aatctctatg aaccaatatt taaaagaaaa gttcagattc ggatggatat tgcagagttt
    15961 tttaactggt gggatcgcat tattaagcgg actgtctttt cagctgcctt tgttttttat
    16021 ccctagcttg ctatttggtt ctttattcgg ctgctactta ttgtcactac gttatttcgc
    16081 tagagattat cggttgctgc tgctgaactg gaccaatatt aaccaattat ttaacagagg
    16141 ttcaggaagt ttgggtttag tcgcaactat gatgggttca ttgatcatca gtattattct
    16201 tatcgtctta tacggaatgt tggctttgtt ttatccattt tggttagtga atattcctgt
    16261 gatcggttta gttctaatac tttccgctct atggatcgtt tattatcaac gaacgttttg
    16321 gaaaaaattt gaataaagaa gaggggccgt gacaaaaatc atgtcgcagc ccctttttta
    16381 cagatagagg gtgttcaaaa gtcagtttct cagtattaag tcaattttat gtaaaaatgt
    16441 gagaagctat ttttacaaaa ctttttttaa tactcataat tacttcttat tgctcctgcg
    16501 gttacttgtc gcaatgtttg tgagatattt tgtcatcgct caaggctgaa cgtctctttc
    16561 acaacctttt ctttgttaca cttcgtttat ttaaaaagcc gtttttttcg tttcatcatg
    16621 attgcgtcac gctttacttt gaaattacgg atgttatggt taaagacttc tgataataca
    16681 agacctaaag cgattgctcc agcaatcata attgcttgga ccgcataatg agccgcttct
    16741 cgataggatt cagtaacgag atttcgaacc gcttgataag ctaaaccacc agggactaga
    16801 ggaaccatcc cgggaatatt gaaaatcgtt acgggcattt tcaaacgttt agagaaaaga
    16861 tcgctgatga atgctactcc taaagaacca agcaatgaac caaaagcagc agatccgcct
    16921 atttgaacac agatccagta gatcatccag ccaaaagcac cagaaagacc acaacaaatc
    16981 aatgaacgcc taggtacatt tgtaataacg gcaaatgccg cagtcgctaa aaaactaaaa
    17041 gaaaactgaa taaatatcgt ccccatactt gtgttccttt cctaataaaa aagctggaaa
    17101 ataaaagcaa tcgcaaaacc gatcatcgta gcagtcatca tcgcttctgt tccgcgagaa
    17161 actcctgaga cataatgtcc agctagcaaa tcacggatag cgttcgtaat ttgaactcca
    17221 ggaactaaag gcatcacaca tccgataatg attagatcct gattgcttcc taagccaaaa
    17281 cgtacgctgt agatagcggc tatgccaatc aataaagaag ataaaaattc cgataaaaat
    17341 ttgattctaa aaaatttcaa actatataga taagctgcgt atcccaatcc tccaatgact
    17401 aaagtcacag gtaaatcggt catctttccg ccaaataaca ccataattgt tccactgatc
    17461 actgccgcgc taacgatttg caaccagaca ggaaagaaag aacggtctcg gtcgattgct
    17521 tgcagttcgc agtaaagttc ttctaatgtt agctctgaag caacatattt acgtgaaaga
    17581 tcatttactt ttactacttt ttctaaatta atcgaacggt tggtaatttg ttccattcgg
    17641 atggtcgagg tacgatcaag accaataaag agaccggttt gagtgacata gctgaccaaa
    17701 cggaaatttc cagaagctaa agcaattcga ctcatcgtat cttctacccg atacatctcc
    17761 gcattgcttt ccatcatgat tttcccagcg agtaaacaag tgtccagcaa cagatctaat
    17821 tcttttcccg tcatagcatc ttctccaata attgattgat tagttttatt ttactacaaa
    17881 acataccaga agcgtaaaga ataaaaaaac ttgaggaagg aataaaagag gcgtatactg
    17941 tttttgtatt gcgggtgtag tttagtggta aaatcccagc ttcccaagct gatgtcgcgg
    18001 gttcgattcc cgtcacccgc ttaaaatagg ttgtgaaaaa gctgctctgc aacaagtaat
    18061 aagaacagcc aagcaaaaac aacttcttat gtttttaact tggatggact tattaccgca
    18121 gatgcaagct tttgcgcacc gtttaccaag cggttgtgaa atcagtgtat tgtcttgagt
    18181 atgaagaaaa tttttgaata ataataaata ccttacagat agagtggtga ctgattagag
    18241 acgaggaatc cgtctctttt ttgtattttt aagccatctt aaaacaggtt ttattttttg
    18301 ctgtttctat ttctttctag tatttattta taggggaaca tatgttaaga tttagggagc
    18361 tgttagtaaa ggagtaaaga aatgagcaaa aaaacaacca aggcgatcgt ggggatcgtc
    18421 gctgctgtga ttgcaggggc attcggtgtt tccaccacac aaaaagattc agatatcttt
    18481 cagcagatta caactatttt tgattccaca ccacaagctt ctcaagtagc ggatgtgcca
    18541 gaatatgatg gaaaacatca agaaatagaa atcaatggga atcagccgga atttacaaaa
    18601 gaggatctta gcctttccaa aggaacatgg gaaagctatt caaatattga taaattgaac
    18661 agagtaggac aagccaatgc tatgcttgga aaagatttgt tccctactga aaagagagag
    18721 cctttgtata ttgacccgac aggttggaaa caaaagaaat taagtgacgg gcaatggtta
    18781 tataatcgca gccatttaat tggtttccag ctgactggtc aaaataacaa cattaaaaac
    18841 ttgatgacag ggacacgttc gttgaatgct ccatacatgc ttgctcacga aaatgatatt
    18901 gcggcatata tcaaagaaac aaatcatcat gtacgctacc gtgtcactcc tcattttgag
    18961 gggaatgaac tggtagccag gggagtgcaa ttggaagcag aaagcattga agacaaaaaa
    19021 attgaattca atgtctttat ctacaatgtt caagatggct acacgatcaa ttatgagaca
    19081 ggacaagcaa caaaaacaaa aaattagtag cagctattcg aattttttat gaatattatg
    19141 aaaaaattgt gtaaaaacat acattcaaag aaatatagcg tatactttat gaaaagagta
    19201 cttttgataa agctacagaa aaaaggaaaa aaacatacaa atagtgtttc ttaatttatt
    19261 cggaagtttg gaatatttgt ttgtagtttt ccctttcttc gagtaaaata aggttgtaga
    19321 aggtaagctg gaattacctt gcgggaaaga ggtgtagaat catgggtttt acagatgaaa
    19381 ccgtacgttt tggttttgac gatagtcgca aaaaagaagt gagcgaaaca ttagcgattg
    19441 tttatcgggc tttggaagaa aaaggctaca atccaatcaa tcagattgtc ggctacttgc
    19501 tttctggaga cccggcctac attcctcgtt atcgtgatgc tcgaaatttg attcgccgtc
    19561 acgaacgcga tgagatcatg gaagtaattg tcaaggacta cctctcaaat catggagtga
    19621 atttatgaga gtaatgggct tggatgtcgg ttctaagaca gtaggtgttg ctatcagtga
    19681 cccctttggc tggacagctc aaggagtaga gatcattcgg atcaatgaag cagaagaaga
    19741 gtttggcttt gatcggttga aggaattagt agcacaatat gaagtagacc ggtttgtagt
    19801 tggattacct aaaaatatga acaattccat cggaccaagg gcagaagctt ccatgtcata
    19861 cggagaaaag atcaaagaac tattctcctt gccagttgat tatcaagatg aacgattaac
    19921 cactgttcag gcagaacgta tgctagtaga gcaggcaaat acttcaagag ccaaacgaaa
    19981 aaaagtcatc gataaattag cagctgtgat gatcttacaa aattatttag acggctcagg
    20041 taagcaatta ttttaataat aaaagaaaag aggtaatctt atgacagaac ataaccattc
    20101 ccacgaccat gaaggacacg aacacatcac attggtggat gaccaaggaa atgaaacatt
    20161 atatgaaatc ctactaacag ttgacggaca agaagaattt ggacgtaact atgttctttt
    20221 atatcctgct ggtgtttcag aagatgaaga tgtagaatta caagcttatg catacatcga
    20281 aaacgaagat ggaacagaag gcgagttaga acaaatcgaa acagacgcag aatgggacat
    20341 gattgaagaa gtattcaata cattcatggc ggaagaagaa gaatagacta taaagctagg
    20401 agaaaccttg atatgatagg gtttctcctt tttttatttt ttactgtatg ccatattgta
    20461 tgccatctag tcaatattta agtgttgtac taatttttca acagtctttt ctttcgtttc
    20521 ttttgccaag tgaccgtaac aatcgatcgt ctgactaatt tttgtatgcc gtaatctagt
    20581 ttgaacttct accatagtag ctccagcgtc caagagcatt gaagcatgag tgtgtcttgc
    20641 tacatgcaca ccgagaaatg gaaccatagc tttttcacaa atagtaatca atcttgcata
    20701 aatagcgtgg tgtgtgatta gttctttata gataccacaa aaaatcatag tcggatcagt
    20761 tacaccaagt gtcagcatat atttccgctg attaatctgc cattttttta atatagaaat
    20821 tgttctttca tctagtggaa gaaccccagc actacaatca gttttaggat cactgatttt
    20881 atagccattt ttggattggc ttagtgtttt attgatggtg accgtatttt cttgaaaatc
    20941 aatgtctgac caattcaatg caagggcttc actgatccta accccgctat aaaagagaaa
    21001 gcgtagtaac gttttatcaa agtcgtttcg ataagtttca ggtttgctgt ttaggtaatc
    21061 aaacaaggtg atcagttgtt ctttactgta aactttgacc ttttctttat gcttagtggt
    21121 ggttctttta ggcattaata cgttgtctag tggattagtc tcaataatcc caagattgat
    21181 agcgtagcta aaaatacgct tagaagttga atgaagtacc ttgtattggt cagtagtttc
    21241 agcccagcta tttacaattt gttgggcttt ttttaccgtg acttcattca cacgaagatt
    21301 tccatatttt ggaagaatcc actttctaaa cttgatttca gttttcatga aggtggcttc
    21361 tcggacagtg gttttatatg tttctagcca caagtcataa acttctttaa acgtttcgtt
    21421 gttcgctttt ttaataccgt ttttatcgta gtccacttgc aagcgtgaca aggcaagctg
    21481 ggcttctttt tttgttttgt aacctcgtct acgaacctta tcaggtttgc cagtcatttt
    21541 gttcattcca agataggctt catagagcca aaatttacct tttttagttt catattgctt
    21601 gaatgttgcc ataatagttt tccctccata gtgtagcaag ccgtgggggc ggttggagga
    21661 ggcagtttat tattattttg aatagtgttt atttagctca gtaacaagag ctgtgaactc
    21721 ttttagaaga tcattttcat aaaattcttg atactctttt ttctcatctg tatttttttc
    21781 tgaatcatta attaatgagt catatcgtaa aagcgtattt agaagagctg cgagataagc
    21841 aattggggta ctcccgtcag gaaattcaat tcgagatcct gttttaagat attttattgc
    21901 gtttgttaaa taaatcttct gtgagacagt caggttatct tcttcgatgt tattgatagc
    21961 attagaaaga ttagaatcaa ttatagagtt atttttttca atagtttttt tcaattgctt
    22021 ttcaagcaca tttcgcttaa tttcgggcat catatgcata tctcttaatg tataagatcc
    22081 gtttaataga taggtagtgg atacatctaa tacctttgaa agttgtttaa gcctggtgtt
    22141 attgggaaga ttatagccat tttcccaatt actaacggca cctttactgg ccggtgggga
    22201 taatttacct ccaagttgtt ccattgagag tcccttttca attctagcca gtctaattct
    22261 ttgtcctgtc tccactgctt cggggtattt ttttctagcc acattttcac caccattcat
    22321 atattttctc tactatatca cgatttaaat atgtgtgaaa cataaaagtt caaaaaagta
    22381 tgttaaaatt cttgcaaatg aaaaggtatg atggtatatt gagtttataa gaggtataga
    22441 aatgtattca agagcctctt gcattttttt aaaatctttg tatagaaatg tatgctaacg
    22501 aggggggata aatatggaat taaaaattga caaactcacg cttgatgatc cagcttttaa
    22561 aattattgac gatcgagttg ttcaacaagt agagcaaact caaggaacgt tactttcatt
    22621 attagaaaaa aagtaccagt ttccaaaata tatgaacaag gcacaagctg ctaagtatat
    22681 gaacgtttca tacaatacta tgatgcagaa atatgttcct aacggtttaa agttgattat
    22741 agttgatgga gtcgtaagaa tttcacaaga tgaatgtgat cgctttatgg aagaatacca
    22801 aaaataaacg caagccgtgg gggcaaaggg attaatagga ggaaataata atggaatcga
    22861 cacaaaataa agcaatcgaa aaagtattat caacaattct tacagaagac acagcggcag
    22921 aattagcaaa cttggaaggc aaagcgctag aagaaacgtt tgaatgtttg tacgaacaaa
    22981 tggactatca aaaattgcta ccacaagaac caacggtaag cggagtattg cgtggcttga
    23041 acgatttagt acaagcagag tttaaagaac gactttctat tgaagagtat caagaaattt
    23101 tgtatcagca agttgagttg ttagcgagct tgctagggct tgaactggag gacgttgaat
    23161 gaaaactgaa atttggaacg gacacattat aagatttgtc gatattaatg atgaatggtg
    23221 ggcagtggcg aaagatgttg cggaagcgtt aggtcttaaa caggttacta gagccattca
    23281 ctctttgcct aaagatgggg ttactactag taaggtcatc gattcattgg gcagaacaca
    23341 agatgtaaac atcatcaacg aaaaaaaata tttaccgcat ggcattcaaa agccgtaaaa
    23401 aagaagccga ggcatttcaa gactggattt tcgacatcat caaagaacta cgccagtcca
    23461 caggacttga aggctttcaa gtattccgca tgctagacaa agaacaccaa aaagaagcaa
    23521 tgactaaatt aagccacgct attactgaac caaaaccagt agactacatt aaagcgaatg
    23581 tgatagccaa taaagctgta tcaactattt atggtcattc caaaatggta aaaaagaaag
    23641 atatgactcc tgaaatgttg gttgatcgtg aacctatttt agatgagaca gtagaattaa
    23701 tgactgttaa agaaaaatat gggttgcagt tttcagtgag tgagaaaatt tataatcgtt
    23761 ctgctgaatt gcagacaact taggagcatt aacatgatcg agaacaaaga aaaagcctta
    23821 tccataacag tcttggcgga caggataaag gcaacttaat tgggataaaa cccgatattc
    23881 tttgttccga ttataccata ttaaaaaatc ggagggaacc attatgaaac gaaacttaat
    23941 tataggaagc attttaatcg gcggaatttt cggcttatta ccattaattg caaaaatagc
    24001 tatctttgca ggattagcgt tatatctctt cactgcttat gacgagtacg actatcaatt
    24061 aagaactgga gggcataagt agatgtacaa aacaaaacta ttaaaccaac tcgatagcct
    24121 tgaattagag gaaattaatc aagggatcgc tgaactagaa aataatatcg ggaaaaccta
    24181 ctttggaaat tcattcaatg aaaaactaac agttttgtat gtactcaaaa aacatgcaga
    24241 acacaaaata atttgtcgag aaatcaacga gctaaaaaat cagattttaa ccgcatggtt
    24301 aaacattact gatatgcaag aagcaagggt gaaaacattt aatacatggg taaagtatca
    24361 gaatcaatta aaaggtgctg aatttgttcg ggatgggttg aaatacgaac ttgagcagtt
    24421 gaagctcatg gaggtgtctg aatgatttat accagtattt tgaaaaagga ggagaggttt
    24481 attggcaaat aattatcaag cagcaacgga attacaaaag tcgggatggt caatttatcc
    24541 cttatctcct ggaactaaaa ttccaataaa aggctctagt ggttggaatg atgcaactaa
    24601 cgattctaat caaattaatg aatggtggac ggaagatgca actagaaata ttgggttaat
    24661 gcttgaagat catcaaatgg tggtagttga cctagatcaa cattctgaaa cacgaaacgg
    24721 cgttgagaat tataaaaaac ttgcttcaat gtatgatcca tttccttcta cttatacgga
    24781 aatcacacca ggtaaaggaa tccatttctt ctttaaaatt cctgatggtg taattatcca
    24841 acaagaaaca ggtgcatttg ctgatatctt cgggcgtgat gataaaggta aaagtttaag
    24901 cgggattgat attatcacta aaggagttcc aatagcgcca actatgatta tttcaagaag
    24961 tgttgggaga gcatatgaac ctattgaaaa cgtatctcta aataatattg caccagctcc
    25021 cgattggcta gtgaacctac tgctaaaaaa accgcaagaa ataaagactc aataccgacc
    25081 cgtagcaaaa acagggacag caaaaaaatt agatatgatt gttcaaggcg ctggcgaagg
    25141 tagtagaaac gatcatttaa ctaagttatg cggttggtta ctatggcacg gtgtagataa
    25201 tcaaacttta gcagaattga tttatacagc aaatgcgtac aatgaaccac cgctaaaaga
    25261 taaagaagtg aatcaaatta ttcgatcgat gattaaaaaa gatttgaggg ggaaagctca
    25321 tggctcataa gcataaatta gatagtattt tagactttcc cgaagccagc gagcgtgaag
    25381 acaatatcat tgaattgaaa acctggatgt cacgattaag atgcaataaa gacgatcaga
    25441 ttaaaagtaa cagtgttgtg aatgcagaat tgattttaac caatgatagc aatttagctg
    25501 gaacaattgc ttataacgaa tttagcggat acattcacct attaaaagat tctccttgga
    25561 tcaatcgtac cgctggagaa tgggaagaca gttttgagga tgccttaacg gcatatattg
    25621 aagaaaacta caatgtagtt tttgatgaca acaaaataca caaagcagta gtaaatgtgg
    25681 ctagaaagaa tgttttcaac ccagtaaaag aacgtatcga aaaagttaaa tgggatcaac
    25741 agcctagact ggaaacactg tttattgacc ttttaggggt agacgacaac ctttacacac
    25801 gagaagtaac aaaacgttgg atagtcggat cagtcgcacg tatctataaa ccaggaataa
    25861 agtttgagat cgttccagtt ttggatggac cgcaagggat tggtaagagt accgttccag
    25921 cattacttta cacggatgat tttttcaccg attcattaga ttcgctaggt gaaaagaaag
    25981 atgattatat gcagcttcaa ggcaatgtaa ttattgaact tggagaatta tcttcaatga
    26041 acaaaactaa aattgaacag ataaaaaact tcatcagtgc caagatcgat aaaattagac
    26101 ctccttatgg tcggaatgtc atagcttggg caaggcaatg tgtatttatt ggaacgtcga
    26161 atgatgggca gtatttgaaa gatgatacag gaaaccgccg tttttatcct ttgccttgta
    26221 agaataagcc aaagatgaat ccgtttaaaa caaaggatga atattttctt caagtgttag
    26281 ctgaagcaaa ggtgcttttt gataaaggac aacgaatcta ttttagtccc gatgaagata
    26341 aagaagtctt agaaattgca aaagactatc aagaggatgc caagatggag aatccaatta
    26401 aagaagcaat cactaaatat ttggaaatgg aaatcccgta taaatgggaa gaagctccag
    26461 cgtgggcgag acgttcttat tatcagaact atcctgacag taaatgtaat gagaaaaatt
    26521 tacagcattt ctataatgga gctactatgc aacaagagtt ttatttagtt gatagcgtac
    26581 tcaccgctga tattttggaa gctgtttttg ataaacaagc aaaggattta ttgaatggtc
    26641 gatcagatgc agaaactaaa aagattgcct tgattattag cagtattcct ggttgggaac
    26701 ggaagcaact gccaaaaaga aataaacgac gaggatttta caataagtca aatgcctatg
    26761 aaaataaaaa tcgagctgga aagtacaaaa agtaacgggt agtaacgggt cagtaacacc
    26821 tagcccgtta ctagtttacc cttactgccc caagggatac agcaatttgg taacggggta
    26881 acaccttatt tccttaaaac ttttgaaata gttagctaat atgctgggga ataatgttac
    26941 tggattttac ccgttacctg ttaccaaaac gctagaaccc ttgtccccgt tgggattgag
    27001 tggtaacggg tacctgttac gtaggtgtta ccacgtgtta cgaatcaagg aggaaagtaa
    27061 atgctcaata ttatttcaac aaacaaagca ccgaactttc aatatacaga tgaaatggat
    27121 cggtttctaa tgaacacgct ggcatttagt gtgggattgg taacagaaga ttattccaca
    27181 tttgatccag aagtattaaa gataatggaa gaagaacctg attggctgca ggagtcagta
    27241 gcgtggtgtc aatcgctagt agtgggatca ttggtagata gtggcaacta tgatgataca
    27301 ggtgagctaa tggatgaatt taattgtctg cttaacctat atgatcgagc gagacaacga
    27361 gagcttacat cgaatgagga taatttgttt ttaaacatcc atgataagtt cttggctttg
    27421 ctactaacag atgatgaatt gataactaat ttattggagg tagaataatt atgcatatgg
    27481 aaagtattag atacttcgat ggtgagaaac acattgagta ttcaaacact caagaagatg
    27541 tagactttat tagttttgag gaagataaaa tcactaaagt taattttaaa gacggaacgt
    27601 gcttgaagat agtttcgcct tatattgaat acaaatcaaa atgggaacaa gatgattctg
    27661 acgaacgaga tcgctttggt tggtaatcta tggcagttaa aaaacaatgt aatcatgctg
    27721 gatgtaaaac attgattgat tataggcaga agtattgtgg gaagcataaa gcaaagcaaa
    27781 cggcaattaa gcgtgaagaa agaaagcaaa gcgaaggtaa atattttcaa ttctatcaaa
    27841 gtagaacatg gcgaaaggct tcatacttgt atcggttaaa tcatccagta tgtgaggatt
    27901 gcctagaaga aggcttgata aggaaagctg atgttgtaga tcacaaaatt gaactaaaag
    27961 atgattggaa tagacggtta gatgaaacta attttcgttc tttatgccat gcacaccata
    28021 attccaagac agccaatgaa agacaaagac gagaaaagag taccctttga gttaaggggg
    28081 catagtgtga aacttactga caatcgatgc ctactcattt tggtacaaat aaccgttgtg
    28141 aaaaggcata agggtaatta caaataacga ttacacttgt aatcacaagt gaaaaagtat
    28201 ataatgaaag taggagattt attgaaaaat acaattgtta ttactgataa aacagggaaa
    28261 cagcgcacca ttgagttacc tcattttggt caagtgacca ttcaaatgca gaacggaaaa
    28321 atcatttata tagataaatt agataaagaa aaattctgat cgaaaaacga aggaatgtga
    28381 gcttaattgc ttacgttcct ttttcttttg tctgaaagga ggacaacatg ggacacccta
    28441 aaatattaca cgatacaaaa ggcaatatat caagtgaaga aaaagcaatc cgtgtggacg
    28501 ctagagaaga attgttcaag cagcaaccat taataaatat cacgccccct gactggatgg
    28561 cagcgagcgc tagaagtgaa tggaatcgta tcgtaccaac attaaaaaaa gattatccat
    28621 tgagtgaagc agattatggt tcattggtag cctattgttt agcctttgct cgaatgaaaa
    28681 cagccgaagc cgagataaga aaatcaggta cgtttatcac atgcgaaaac ggagtaaaga
    28741 aagccaatcc agcggttcgg gttcaatcac aagctatgag tgatttgaaa aaacaagcca
    28801 cctcactagg tatgacctta gaatcacgat caaaactagc tttgaacaag gttaaaaatg
    28861 atgaacccga agacccgttc aaagagttga tgaattcatg aatgattaca ttgagaaagt
    28921 cctatcaggt aagctgattg cacccaagaa aattatccaa gcgtgtgagc gtcatataag
    28981 cgatttggag cgttctaagt cagatagctt cccttatgtg ttcgatgaag aacaagccac
    29041 caaagcgatt aaattcattg agttgctacc atctacggac ggtaaagcaa tcaagatgtt
    29101 aggatttcaa aaattcattc taggcagtct ttatggctgg cgtactaaag aagggaatta
    29161 caggcgattc aatcgagcgt ttaccagtat gagccgtaag aatgggaaaa cgtatatcgc
    29221 aagtggcatg gctgccaatg cgttgattat ggaacaagaa ccagcagaag caaggcaagt
    29281 attgtttgta agtaacgctt tgaaacaagc taaattgggc tatgatatgc tgtctaattc
    29341 acttagaaac gtggtcaagt ctagtaagtt tttaagacca caactgaaaa ttatgaactc
    29401 taagattcag cacttgccct ctaattcgtt cgctatggca ctggctagtg aaaccagcac
    29461 gctagatggg tttgcaccaa caaccgcaat tcttgacgag tggcacgaag caaaaactcg
    29521 taaaacgtac aacgtcatta agtcaggaat gacccaacaa aagaacggct tattgtgtgt
    29581 tattagtacc gctgggcttg atttaaacgt tcctatgtac gaggaatact tattgttaga
    29641 tcgtgtgcta aaaggcgaag aacaagccga caggtacttt atagcgatat gggaattgga
    29701 cgatcccgaa gaaattcacg atcaagagaa atggatcaaa gccaatccga tttttgaaag
    29761 tgaagaaatc aaaaaagtaa tgattccaac cattcaagat gatgtgaacc ttgctttgaa
    29821 acaaaataac cttaattctg tattggtgaa aaacttcaat ttatggagac aagcgagtga
    29881 ggacagctat atgattgctg aagactggca ggcaaccgaa gtagaaccac aagatattac
    29941 aggcaagccc gtttatatcg gagtggattt atctaaaaca gatgatttaa ctagcgtttc
    30001 atggatcgta ccgctagata acggcgaact ttattgtgat tcacatagct ttgtagccac
    30061 caaatatggg cttcaagaca aagaaaagcg cgacggtttg ccttatcgag aactagaaaa
    30121 agctggtgag tgttccatta ctcaattaga aagtggaatc gtggactatg accaagtatt
    30181 tcagtttatt caagatttga ttcaagaaaa tgatttggaa tgtatgggga tttgttatga
    30241 cccgtataac gctaattcgc ttatcagtaa agctgaaaaa gccaactacc caatgttaga
    30301 agtaagacaa ggaacgatta ctctaaacgt tccgacccga acttttagag aacaagttta
    30361 tgaaggcaac gttattcaca ataaaaatac gattctcacc catgcagtga acaacgctat
    30421 tttaaaaacg gataacaacg gcattcagat taataaatca aagaacagta acaaaattga
    30481 tccaatagct gcattaatca atgcctatgt gtttgcaatg gattacttca ccacaacgga
    30541 aggagcgaaa gcagacaatg aattttatac aagtgaagaa ttttctttct aattacattc
    30601 ataccgttct tttacttctt ggattggtgt gtgtgttggt tgctatcacc ttactaacaa
    30661 atgtctacta tggcttgtta gcgctgggca tagtgcttat tggggtagcg gtcatgctaa
    30721 atacagaaca gaagggaggt taaaagatgg cattttttaa agagagacaa aatacaacgg
    30781 gagatccttt cctacaacat gtggtatcaa tccaatcgga tgattacacc accagcttta
    30841 caagcgttcg tgcattaaga aatagtgatg tgtttgcagc cgttcgaatt attgctagtg
    30901 atattgcttc aagtccgatt caattggtca aaaacaatat gccacaagct gataatgaac
    30961 tggtgaagtt actaaacgag aaacctaatt cagaaatgga tggttggcat ttaaagtttg
    31021 ctttggcggt caatatgttg ctaaacggta atagctttgc agagattaaa cgcaacggtg
    31081 aaaaggtaga agaaattcac ttattaccta actcaagtgt aacggttact caattagata
    31141 atggtacgtt gtcttatcag attggtgata aaaaaagacg tgtgaagtct agcgatattt
    31201 tgcacttcaa atatttcacc caagatggtt taacaggatt accaccactt tatgcgttac
    31261 gtgatgaact gaaaattcaa caagctggca accgcacatt gcacaatttc tttactcgtg
    31321 gtgtcagtgg gtcaggtatt ttgaaggttc ataagtcaga tttagacgga tcagcaaaga
    31381 acgcaattcg tgaaaagttt gaagaagcca acggttcaag tagtggagat aatgctctta
    31441 gaacgatcat tcttgatgaa acaatggact acaaaacatt agaaataaac accgatgttt
    31501 tgaagcttat caattccaat gattggaaca caaaacaaat tgccaaggcg tttggtgtac
    31561 cgattgagcg tttaggcgtt gaaaatgaac attctagcac cgttcaaagt aatctccagt
    31621 atatccaaag tacgctgatt cattacttta atgtgtttgt gagtgaatta gatacgaaac
    31681 ttgaaaccaa tatccgcttt aattccgatc agttactaga gactgatcct gaaacaaaag
    31741 taaaaaatgt attggatcag gtcaaagggt cacttctcac gattaatgag gggcggtcga
    31801 aaatggggct accccccatg gatggtggcg atcgtttact agcaagtttg aactttacgt
    31861 atttagatac gttggagaaa tatcaattaa aagaacagga aggagttaca ccagttgaat
    31921 aatgaagaag aaaaggaaaa acggctgaca gaagaagctg agctaacagc cgattctccc
    31981 aaagtagaga aagaaaatga aaaacaacca acagacggca aaactatttc aggctatgcg
    32041 ttgaaattcg ggcaaccgtc aaaagattta ggcggctttg tagaagtgat tacacccgaa
    32101 gcattaaaag aggtggattt atcaaatgtg ttcttattat atggacacga ttattcaaag
    32161 ccactagcta gtgtcaaagc aggtacgttg aaattgaatg tcgatgatac aggattacat
    32221 tttgaagcag agctaaccga cacgacctat tcaaatgatg tgtatgagaa tatctcaaaa
    32281 ggggttgttg attctatgtc ctttgggttc gtgcttggat tagattcatt cgacaaaaaa
    32341 gaagatggca caattgaacg atcaatagat aaaatcaaag cacttaatga aattagtgtc
    32401 gtgaccgttc ccgcttatga ttcatcaaat gtccaagtaa ataagcgttc ttacgaatcg
    32461 tttatgagta acaaccaagc aaaacaaaca aacaatagct tagaatccac ttctaaagca
    32521 caaaaggaga gtaataacat ggaaaaaact ttaatcgata acgaaaaaac agaattgcgt
    32581 gggtatgaag aatatatccg ttcacaaggc gaagtgcgtg atggagtcac tactgtaaat
    32641 gcagcggcag ttgttcccga agaagtaatc ggtgaagtct ttgatttgaa acgttcaaat
    32701 tataacttag ctcaatatgc aacagtaaaa acagtatcaa atggacaagg taaatatcca
    32761 gtagcaacta accaacaagc agtgttagca acaaaagctg aacttgctga aattggtgat
    32821 attgacgctg aaatgtttac ttcagttgat tataaagtag aaactcgtgc tggtaagatt
    32881 gccttatcaa atgaggttgt ggaagattca gcagtgaata ttgtacaaga ggtcaaagat
    32941 cagttagcga aattggtaga aaacactgac aataagcata tcatggattt attaaaaaca
    33001 ttcactaaga aaacggctgc tacgttggac gatttgaaac aactatacaa tgtggcatta
    33061 gacccagcat taaataaaat ggtaattcta aaccaaagcg gatattacca cctagataca
    33121 ttgaaagatt cagatggacg ttacatttta caacccgatg tgacagcacc tagtggtaaa
    33181 tcattattcg gtatgccagt agtattgatt gcagatacat tgtttgccaa tcctaaagct
    33241 ggaacattcc ctatgattat gggggatatt gcacaatcta tctttgttgc tcgtagaaat
    33301 caagtaacga ctcaatggga aaaattcgat tactactcac aaggacttgc agtgatcgtt
    33361 cgcaacgatt ataagaaaat tgatcaaaat gcttcagtgt atattgagtt tacgccagtt
    33421 gtaacaccaa aagtatagaa aaatattggg cggcggttta tcccactgcc tttttttcat
    33481 taggagagat aaaatggtaa ttttggatag cataaaaaaa agtatgcgga tcgatcacac
    33541 tattgatgat gactttattc aacaattgat tgatacagca ggcgaatata taaaaagtgc
    33601 tattgatagt agcgcaacgg ataaagatat ggataattat cagcaatttg atttggcggt
    33661 gtcattactt actcaacatt ggtatttgaa ccgtcaagaa gccagcagcg aacggatacc
    33721 agtaacggta caagcattag tacaacaaat gagaggtgct tattatgcca atcattaaga
    33781 atgtaaatga attgactgag agagtcaagt ttaaaaagac aaaacgggta aaagatgaag
    33841 atgggcagat ggtggatagt gaagaaactg tatttgaatg ttgggctaat gtgcgttcac
    33901 aaatgctaaa agacgtgctt gctagtgtag gtaccattct tgaaggaacg ttgacgttta
    33961 ttattcgata cgatcaagat tatgaactaa caaacgatat gaaagtagct tggaaaaaca
    34021 agagttataa aattatttca atcaatgaag gaacggcgtt taaagattat acaacgatca
    34081 tagctaaaca gatttcttag aatgattaca cttgtaaacg ttgtgggtat ttagtataat
    34141 taaggtagta aatgaagggt tagctgcctg aattttgcaa gacttagcta gtcgaaatct
    34201 attgttggac tgaaaattgt aggtgtggtt gcaaacatgc tggactaaga aagatgatag
    34261 atgatgaacg ttcaatttta atacaggcat gctaggactg attggatggt tttggcaagc
    34321 tgattgtgta gaaatcaaag aacacgtctg ttgtggacgt gttttttttg ttataattca
    34381 aaagaggtga tttaatggac aaagcagagt ttacaaattt ttattggaag tattatctac
    34441 atttagaaaa tgagtttatt aataccacag attttgtgat gctcgatgag aataatttca
    34501 aaacattctc tattgaatat caaaaactac tactagcgat tggttcggag tgtgagatta
    34561 ttttcaaaga actttgcgga tttgatagca gtagcaataa aagcataact gattttaaag
    34621 ctgttattaa atctagcgaa ttaatgtgtt tggataatgg tgttagggtt atgaattctt
    34681 taacattgac ttcactaaaa ccttttggag atgggtggcc tgaagataca ccagattggt
    34741 ggaaaatata taacagagta aaacatggtc gttcttcaaa ttataaggaa gcaaatttgg
    34801 aaaatgtgtt gtatgcttta gcaagtctat atttattaga ggaatatttg cataagaaag
    34861 taatactaga aggtgaagta gactttataa gtccagagtc aaatctattt acgttatctt
    34921 gggaaagaaa acattcgtcg atgcaaaaag tgacgtttga aaaagtggat tcaaattatg
    34981 tagctccact cattgatttt aaagaacaag aagaaattta aaaaccccca cggcttattg
    35041 aagtttttgt atgccatatt gtatgccatt tggtttaaat cgcttgaaaa atagtgatag
    35101 ataactctaa ttcatttagt cataaacgct gttttgataa cctttatagt tctttgatat
    35161 gggtttctca ttcatggcgg aagaagaaga atagaacaaa agaatgaatt aataagatat
    35221 aaaaaaaggg attgtgacaa acgtcttgtc acaatccctt tttccaaata aacgatgttc
    35281 aatcagctgc ccctcggcat tcgctcgaaa aacggcgaaa tatgaagaac tattttgcca
    35341 tttgtttctc taataatcag gtcaaaacgt tgacttcaca gtctcttcct taaacggtgt
    35401 tctcctgcca actcctcggt cacaagtcac aatattcaac aaacatgaga agctgttttt
    35461 tgaaattgtt ccttgtgact cggagctgaa cggcaggctc acgacctctt tcttaaacgg
    35521 tgttcaaaag cttgcatctg cggtaataag ttcaaccaaa cgaaaattat gaggagctat
    35581 ttttgtttgg ctgttcttat tacttgatgc aggacagctt tttcacaacc tcttttcgtt
    35641 tagcactaaa tttccttaaa aagtagaaaa gctttcgaag cctcgtttgt ttcttttact
    35701 gtataataaa agaaaagagt aacaatcgct aaaagatata aacaagagaa aggaaataca
    35761 agatgattgg tctgatttat tttgtggtga tcgttctggc gaacacagtt ggcgctattt
    35821 ccgggatggg tggaggcgtg ttgatcaaac cgattcttga tcttatcggc gcccattctg
    35881 ttgcagggat ttctttttac tcaacagttg cggtattcac gatgtccatt gtttcgactg
    35941 tgcgacaagt atcaagcggg aaatcactga attggcagat tgtcggttgg gtatctagtg
    36001 gagctgttgt tggaggagta gtcggcaaca ttgtattcga agttttttta cagttatttg
    36061 aaaacgagaa gcatgtgcag ctgatccaaa tttttttgac ggtattgacc ttggtttttg
    36121 cgttcttcta caccaagcat catcagccaa aatttcattt gacgtcatgg acttggtacc
    36181 ttatatgtgg gggggttctg ggctttttag ctagtttttt aggtattggt ggtggaccag
    36241 tcaatgtttc tttgttgatg ctgatgtttg cattgccaat aaaagaagca acactatatt
    36301 ctctatctac gattttcttt tctcaactgg caaaattggt aacgattgct ttaacaagta
    36361 gctttatgcg ctttgattta tctatgttgt tttatgttat ccccgctgct gttattggag
    36421 gtttgtgggg agcaagattt agcagggttt tgtctccaaa aaaagtgacc tttatttttc
    36481 aagtaattgt cctcgtggtt cttttggtca attgttacaa tgcctttgtc atcttacaaa
    36541 cattaggaga atctagacta acgcaagtca aaatcactga aacatattgt tctaaatgaa
    36601 aaaaagagta tactatgata aaaaaattca ttttaaaaaa tcagaaattg gctggtgatt
    36661 tggatgttac gggaaatgcg tttagaagat gcagaagcac tacgtgaaat caatgcggat
    36721 caattagggt atgatatacc attaaccgtt acggtgagac aaatgaagaa actgctgaag
    36781 gagccagaga aaaatttttt cttggtttat gaagatccta cttctaaaaa agcagctggc
    36841 tatgtacaag cggagtccta tgaatcgatt tttagcgatc caatgttcaa tattatggca
    36901 cttgctgtgt ctaaatatgc tgaaaaaaga ggcatcggaa aggctttgat gactggcgta
    36961 gaagaagaag cgaaaaaacg aggaataacg acaataaggc ttaattctgc agaatacaga
    37021 gtagaagcac accaatttta tgaacacatc ggttatcatt ccgataaaat gcaaaaaaga
    37081 tttttgaaaa tcctgtaaat ctttatcaaa aaaatacccg atcaccaagc cgatacttga
    37141 tgatcaggta tttttgtttt tttgactaag aaagtaattg catcaagaaa ccagagatga
    37201 tcaaaacgat ggcaccacca agtcgattgc ccatttgagc aaaagcaata agttccatcc
    37261 gattagctgc agataagacg gctacatttc ctgttccgcc catcgagttg ttgcataagc
    37321 cagcagtaat agttgattca attggatata aaccaaacaa acgaccgaca aatcctgaaa
    37381 caactgaaat cgcgataaca cttgtcagac ataagacaac aaattgccat gtcaaagcag
    37441 aagctaatac attcagattc agcaacgcaa taccgatacc ggcaagaaca gctgctgtca
    37501 agtttttgac aatcaagtta ttgaacatga tagctgcatc ttcataatac tctggtaata
    37561 ggttggcgat tttacagatg acaacgataa taatcataaa tgcgtaagca tggactttag
    37621 gaacaaaata gttaccaatt tgtcctaaga tgaagaaagt caatgatacc atcaaaccaa
    37681 cacctaactg tggaatggaa ggtttcacag ttcgaggttt tccatcgcca agatcgcctt
    37741 tttccattaa tttaccattg ccgttgaatt ttggcattga ttgtccagca cgagcaacta
    37801 atgctgcacc gatgatagct aagacatttg tcattgctgt cgcaggaatc aggcgggaaa
    37861 tgatagaaga agcatccgta cctaaaacat ttgcataaat cgttgataaa ggaacggctc
    37921 cggctccaac accaccagcc atcgcaggta atgagatgta taaaacggaa tttgcaaaac
    37981 catttccgat aagcatgccc acgagtccta cggcaaaaaa ggagacgacc attgaaataa
    38041 gtgcaacggg aataaaacga acagaagctt tcatcaatag attacggttc ataccaagga
    38101 tgctaccagt aatcaaggca gcaatataaa agtcccaaaa gcccatattg ctgacaaagt
    38161 tttctgtgga tttcactaca tattcaggta agatcccaaa tgtagcaatc gcagcagaag
    38221 cgaagatcgc aaaaacggaa ccaccaccca aataactttt gacgataggg atttttgtcc
    38281 cgataaaatg aaataaatta ccgaaaataa ccaaaactgc gattggtcca atcatattcg
    38341 tcggtaattt ccctaaagcc attgcaatga tcaggacaag gaccatgatc aaataaagtg
    38401 gcaaacttac gccggtgatt tttgtggacc aaaaaccttc ttttttcttt tcctcaactg
    38461 cagttgcagt tgttgttttt tgtgccattt ttacagatcc tttcttattc tgtatcatat
    38521 gaaaaaagcc aaagaaaagc gacaaaagag caggagttgg ctggccgctg ttttgccgca
    38581 gtcgcttttt tctttttaga cgtcatacaa agtttctgta tgttctttta ctataacgat
    38641 cttaatcttc taaagattta tattcaggaa cccatttagc agattcaact gcttctttga
    38701 tatccgtgat ttcttcacga ttcaagtttt gtgcgacaac tgattttgcg acagtttcag
    38761 caatcgtttg agaaaattca gtgatttttg ctactggagg caagatagct gctcctggtt
    38821 ttgttacatc aacgattccg cctaatgctc gactagcttg agaaatgatt tcagcattta
    38881 ctcgtgtagc tgttgaagca atcaaaccaa gtcctaaacc tgggtacatc aaagcattat
    38941 ttgcttgacc gatttggtaa gttacaccat tatattcaac atcagcagca gggatacctg
    39001 ttccaactaa tgcttttccg tccgtccatt ctattaaatc ttttgctttt gcttctgcca
    39061 attttgttgg attagacaaa ggcatgatga tcggacgtgg tgtatgagca gccatttctt
    39121 tcacgatttc ttcagtgaat gctccaggtt gggtagaagt accaatcatg attgtcggat
    39181 ggatcgcttt tacaactgct tctaagtttg tcaattcatc agcattagtg aaatctgagc
    39241 gtttgcgagc gaatgggatt tgaccaggag tcaatccttc tgtatcttca aacaataaac
    39301 cttgtttatc tacttgatag aaatgttggc gtgcttcttc ttcaggtaca ccttgacgga
    39361 tcatctcatc taaaaggatg tttgcgatac ccacaccagc agtaccagca ccaaatgtca
    39421 aaattatttg atctttcaat tgttcaccgg atatattcaa tccgcctaat acacctgcta
    39481 ggacaacaat tcctgtacct tggatatcgt cgttgaaagt agtgatttga tcttcgtatt
    39541 tttctaagat cgctgcagca tttcctcgtc caaaatcttc ccaatgcaat aacaattctg
    39601 ggaataattc ggtagctgat tgaacgaatt gatcgatgaa ttcatagtaa gtttcgcctt
    39661 ctacacgagc atgacgattg cctaagtata agggattatt caataattct tcattattag
    39721 taccagcgtc gatcgataca ggcaaaactt gtgctggatt aataccagca gcagcagtat
    39781 agaccatcaa tttgccgata gcgatgtcaa caccgttcac accccagtcg cccataccta
    39841 agattccttc tgcatcagtc acaacaatca aacgaatgtc tcgtccatct gccgcgttct
    39901 tcaaacttgc tttgatgttt tctggttcgt cgattgaaag aaatgcagca tcttgcggtt
    39961 tcaagaaaat ttcgttgtat tgttcgattg aatccgcaac gacaggatca taaacgacag
    40021 gcatgaattc aactaaatgt tcgcccatca atttataaaa caatgtccga ttcgtattga
    40081 atagattcat taagaagata cgtttttcca aatctgtttg tttgcttaag tattgaccat
    40141 aagcttgaac agattgttgt tccagtgttt ggacagtact tggaagcata ccagtgattc
    40201 catattttgc ccgttcttct tttgtaaaag ctgttccttt atttagaaaa ggattattta
    40261 ataagtttaa ccctgtaagc atgaatgatt cctcctaagt tttaatacaa acgaagtata
    40321 gaagtcagat gatgatatag tcaaaaagag caggtatgat aaattttatt tatatgtaat
    40381 atagccaaaa gaaatcaaaa tagcagtatt tgttcttttt atatcgacaa tccttgcttg
    40441 aatactatgc gtatctctta tatgctagag aaagaaaagt agaagaataa gggatagatg
    40501 gaatggataa ataggatttc tgaggaaaaa agcacatgat agcgttgata ggagtcacct
    40561 atgtcaggtg ataaaaatac ataagtagaa aattaagagg aggaagagaa aatgaaagaa
    40621 gttcaattga ttagaaaaag cgaactatca gaaggcggtt gcaatgcatg tggcgtagta
    40681 gaagcgacaa gctatacatt aaaattagat tccaatcaag caataatctc tgaactgaca
    40741 gtaggcggtc ttgtggacag tctggcgctt gctgaaggtt ttactggaga agatatttat
    40801 gagatgtttt cagaagtccg tcagttaaaa aaaggagaaa aatgcataga ggttcatcat
    40861 gagagcccga atgtgaggtt caaacgtggt gataatgaga tgatcttcaa gaatcatgtg
    40921 tctgatcaca ctgaactata tgaaatcgtg aatcaaatac tgtctgggat ttttgaatta
    40981 ggaccttatg agttcaagga agaaaacggt aatccaaaat taaatgaaga atggcaagaa
    41041 acgattgaaa cacaaagaaa caatccacac ttatttcaat agtcttccac agtatttcgt
    41101 aaaaatgttg atgaaaaaga aacaccgtga atcagaggtt gtgaaaaagt cgcttagttt
    41161 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta
    41221 ataccgagaa aatggctttt gaacaccgtt tattcaaaaa aagggacttt gacactactt
    41281 ttgtcaaagt cccatcggtt ttttatctat ttttattaca atcatttctt ccagagtagt
    41341 gacatctgga atggctgaaa tgtaaacaga ttatttgcct gtatcaatgt cgaagagtaa
    41401 tataaaaagt gtaaacgcta tcatattgtt catcattcaa attttataga gagaaggcat
    41461 tgagatggaa aaaacatatc aagcaggtac aaatgaagga atagtagatt ttatcaatat
    41521 ggaagattta gaaatcgcgg cttcacaagt gattccagct ggtggttatg gttacatcag
    41581 cagtggtgct ggcgacttat ttacttatca agaaaatgaa cgggcattca atcatcgttt
    41641 gattattcct catgtattaa gagatgtaga attacccgat acaactacac attttgacga
    41701 agaaatgctg actgcaccaa tcatcatggc accagttgct gctcatggat tagctcatgt
    41761 gaaggcggag aaagcttctg caaaaggtgt agcagatttt gggacgatct atacagcaag
    41821 ttcttacgct tcttgtactt tagaagagat aagagaagca ggcggggaga aagcaccgca
    41881 atggtttcaa ttttatatga gcaaagataa tggaatcaat ttggatattc ttgaagtggc
    41941 caagcgtaat ggagcaaaag caatcgtatt gacagcggat gcaacagttg gcggaaaccg
    42001 tgaaacagac cgcagaaacg ggtttacctt cccgctgcca atgccgatcg ttcaggctta
    42061 tcaatcagga gtaggccaaa cgatggatgc tgtatataaa tcttccaaac aaaaacttag
    42121 tccaaaagat gtagaattta tcgctgctca ttctgatttg ccagtctacg tgaaaggtgt
    42181 tcaatcagaa gaagatgtct atcgatcatt agaatctggt gctggtggaa tttgggtatc
    42241 taaccatggt ggccgtcaat tagatggggg gcctgctgcg tttgattcgt tgcaatatgt
    42301 ggcagaagca gtagataaac gtgtaccaat cgtgtttgac agcggtgtac gacgtggaca
    42361 acatgttttc aaagcaatcg catcaggtgc cgatcttgtt gctattggca gacccgttat
    42421 ttatggattg tctttaggag gaagtacagg agtccatcaa gtgtttgatt tctttaaaac
    42481 agaattggaa atggtcatgc aattagctgg aacacaaaca gtagaagata tcaaaaaaat
    42541 aaaattgcgt gagaatcgtt ttatttaaga aataaatgac gaaaaaaata ggagtgcggc
    42601 agatgatgcc gtactcctat ttttatagtt caaggatgtc actaatagaa taatttgaaa
    42661 cgaaaaaata aaattgaaat attttttcat acttaataaa aaaggaagaa tattcatgta
    42721 aacgatttta ttgttttttt ctcttttata caaaaagggt cataatttca agtaagcgga
    42781 tgaattcatg aggatttttt gcatactgtc tctactatac ttaggtcact aagaaaaagg
    42841 agtgatttat tatgaaaaag aacatgattg ggacattatt actttcaaca cttcttctag
    42901 gcggcttggc aacaccagct tttgctgagg gtcaagcgac ttcaaaagga gatattacct
    42961 ttactgaacc aacaaatacc gttgagcctc ttaaccctac tgatccttca aaaccagtag
    43021 agccagcaga tccggaaaat ccagcaactg gccagacagg ttctttaaca ttggatgtag
    43081 ttcctgaatt gccatttggt acacacgaga ttgaaagcgg aacaaaaacg tatcaagtag
    43141 acgcttcaaa aaacgataca ccttatctcc aagtatcaga tcgtcgaggt gtaggtgcag
    43201 atggccaagc acaagggtgg aacgtgacag tttcggtttc agattttgta aacggttcac
    43261 aagttttgca aggcgctgaa ttagattttg gaacatccac tgttaaaagt acgtcagata
    43321 acgaatccac tggaccaact agtcaaactg taactgggtt gagtaaagca agtgcagcga
    43381 caccaatatt tacagcagca aaagatcaag gtctgggaac atggctttct gtttatgatc
    43441 cagcaaatat cacactgaaa gtgccgaaag cagcagctgg aacattcacg gctgatttga
    43501 cttggaacct cgtggctggc ccagtagcat agagtatgaa ataaattcaa caaactgcgg
    43561 tgaaaatact ataggtgaag gattttttac cgcagttgtt gttgaaagga tgtggtggac
    43621 aatgaatcaa agtaaacgac tgtttgtttc gtttttttct attttaagtc tatttttcat
    43681 ttttccgtca atcagccaag caaaggattc agcaggagac tttggaatca aaccggtatt
    43741 tccagagaac caaatagata aagcaatcgg ttattttgat ttattagtgg caccggaaca
    43801 aaatcagaca ctagaagtaa ttatcagcaa ttcttcagat gaagaacgaa catttgaggt
    43861 ctctgtcaat ccggcggtaa cgagtgatgg tggaacgatc gattatagtc aaaaaaaccc
    43921 aacgttagat gagacattgc cgtttgatgt ccgtgacgtt ttgctcattg cgaaaaagga
    43981 aatcaatgta tcagcacatg cagaaacaac tatacctata gaagtgaaaa tcccagcaaa
    44041 aagctttaag ggacgtgtat tagcgggtat tcatgtttca cctaaagaag aagctgaaac
    44101 agaaaatgct acagaaggag cacaaatcaa aaatcgtatt gcttataatc tcgcagtcgt
    44161 tttacaagaa agtcaagaga cgatagaacc ggatctgaaa cttttatcag gagatttgga
    44221 cgaggtcaac gcaaagccaa ctgttcagct tcgtttccaa aatcctcagc ctaggattat
    44281 cagcaatttg atatttacga gcaagatctt ttatgaaaat cagctttata ttgaaaatac
    44341 gtctaatgaa tttttagttg caccaaattc gaattttcac ttgaatcttg atttagctgg
    44401 tgataaagca aaagccggcg attaccgcgc agaaatcata gcaaaatcag gcgacagtaa
    44461 tgaatggcga tttacacaaa actttacgat caaaaaagaa aaagcacaaa aagtaaatga
    44521 aaattccgtt tttgcagtac aagaacaatc tttcccatgg ctttatgcag gattggttgc
    44581 tgcagttcta gtgttatggt tgattttgct gtttttgtgg gtccacaaga aaaagaaaaa
    44641 aggagaaaca acatgatgag gtgatttcgt tgaaaacatc gatcttattg ggagggatta
    44701 ttgcaagttt gctgttcttc agctggcaag agccagtcca agcagatacc aaaagttcag
    44761 gtacgattac attttatgat ctaagtccag ttccgcatcc aagtggttca gtcaatggcg
    44821 catcaaaaca gcagacacag ctaccgattt ataaagaatc taatcaacat ggcgtattcc
    44881 cggagacgaa tgaagaaaag atccgttttc tttatttgat cattggtata gaattatggc
    44941 ttcttgcgtg gttgttgtta tggagaagaa aggaaaagga ggatgaacat gttgctacaa
    45001 aataaatttt cattttttcg ctccttcttt tttacttcgc tttttgtttt aagtatattt
    45061 atcttttcac cttcggcaga agctgttgga gcaacgcctc ctgccatttc ttatgatcca
    45121 tacacgtatg aaaatatcgt acctccaaat ggtggacgta gtgcagtcaa tggcgggaag
    45181 cttgtccaac taactggggc taaccaattg cctaaattga ctgctactta tttgaacgat
    45241 ggttcaaatg atccttggaa aggtggcacg gtccgttttc attgggaaag ccatgtgaaa
    45301 ctaacaaatg tacttgattt ggtgaatatc actgcacaag gatttgcatt tgtggcgatc
    45361 atcaatttgc cggaacatgt atcaagcagt gatgtattaa aagcaattga ctggaacaac
    45421 gcctacttgt atattgccgg tgcccccatc aaggttacta gcggtagttt attatcagca
    45481 ggaagccata ccttgcgttt tgggatgggg tcgtgggata caaatactct attggcagat
    45541 attattgcta ttattacgcg aggcgaattc aacgtggacg atatcccgct tcaatttgat
    45601 gttacagcta atgtcgcgaa gatgacagaa aacggagata aatatgatac gagtccaaac
    45661 aaaattttga ccaagggtaa attacaacct tctatgtcta aaaaggccgt tttttctgtt
    45721 gatttttatg attcgaataa tattatccaa gatcgtatgt tcaattcgat tttagctcca
    45781 gctgcaggta gattttatcc taaattaact ggcggaaact tgaatccagg agcatatgca
    45841 ttttctgcaa gtgcagagat aaatacgtgg aatagttaca tctcaacaag tgattcaaca
    45901 ggaaaatata atacatttgc tgataccaca gaatacgtgg atggaaataa ccagaacctt
    45961 ccaggctcta ccaatagtcg gacattgacg atggggctga ctgaaggacg ttttgatcag
    46021 ttgccattta gtcgctttga tcgcgtagtc aactatttta caggaaaaaa cgttacacaa
    46081 ggagcaatac tgactcatac tccagcaagc acaagtggat tgaatcagac agccaatatc
    46141 gtgtacagtg ggaaagatgc gcaaggcgga ttgctttctc ctgttgcttt aaaggtattg
    46201 gagcagtaca agctagacgg aacggtttta ccaacaaact taacagccga tagtcagtgg
    46261 ggaaagctcc tttcttctgc atcgtaccaa gtcacggcca attggtcagc aactgaacta
    46321 aaaaagggtt cgatccatta caggctttat tcgaaaggaa cccaaaaatt agcgacagga
    46381 tggacagatc aacttttcca aacgatccaa tcaaataacg ggggtgtaaa tacagctact
    46441 tctacactac ctgcattggc ttcagggcaa tattattttg attatcgctt ggtggacgat
    46501 gtacttacta acatgtatcc gtcttttgcg tacaaatggc agtctgaaca agctggaatc
    46561 accactcttc ctcaaataac agtggctaat tttccatctg tgagtgcaga tagtcagcta
    46621 aaaaacctta gcagacaacc tgagacagga gatcccctgt ctgctctatc aggagatacg
    46681 attcaagaaa atgtgacatt cacgttaaca aaatctgggg atgcgataac cgacaaaaaa
    46741 atcacgatct cacttcctga aaatactact tatatcaatg gttccttaaa attaaatggt
    46801 acaactatcg cagataccgg cattcaacaa ggagtttctg tcccagcaga tctattgagc
    46861 aaaataggag ataccattca tcttacttac aactatcaat taaatactgt agatacttct
    46921 gtacaatccg tcagcatact gacaaaggca gctgtacttt ccagcaatat tacattagca
    46981 gatggtgcta agcttcctaa cccagttgtc caaacatctg ctaaaacaat tcttgtcccc
    47041 aaacaagaat taacattagt taatgtacca gatgatttta catttggtaa cgatctcccc
    47101 aaaccgttga agacaagtta ttatgaagca aaaggcgatt tttcttttga tgtgcgggat
    47161 actcggcttc caagcacgtc tccttggcaa ctgacaggga cattgacttc tttatttaag
    47221 aatgatcaag gtcaagaatt aagcggaaca aaattatact tcaatcattc tggatcaaaa
    47281 caattgattc agcaaggtca aaacacgttg atttatgaga gtgatggaac agctaaagga
    47341 gaggttctcg ttgactttcc cgataccgat ggtttactct tagaggtaaa tagcagtacg
    47401 aatgctcaac ctggcgcaac gtatcaaggc atggtcacat gggaactgac agctgggcca
    47461 accagctaag tgattagaat ttgtatggat ctgtgataac tgtcacagat cctctttttc
    47521 aaggatgaga aggaaacttc tgctgttaaa atcagaaatg cttggaggag tggacttgga
    47581 acttttcagt ttgcttgaaa aaaatgaaca acggcaaatc aaacttttcc aacttttatt
    47641 agaggaaaaa ggagagattt ccgttaataa cgtacttacc cgcttatcag ttgatcgggc
    47701 taccttgaaa gaagatctgt tttatttaca agctaacttg gaaaatatca aacaattgga
    47761 aattgttatc caagaaggga atattttatt aatcagacat ggaaatatag cagcagtcga
    47821 tgtttattat cattgctact tgcgctattc tacaaaatat cagatacttc tttatctgtt
    47881 ggaaaatggc tcatttgatc ggcagaaact tgtcatggaa cttaatatca gttcggctac
    47941 tttgtctcgc agagtgaagg aattaaatga ttctttaaat gagtttcatc tgaaaataaa
    48001 aagcgggcgg ctgaccggtc cagaaagtca aatttgttat ttttatttcc aattattttg
    48061 gtttggacgt ccttatcttg aaaacaaaaa agaatacagt gatttatcag gaaacacttt
    48121 tttagatctg ctgcaaaaag agtttagttt tactattaca gaagaaggac gattgaaatt
    48181 tgaaatatgg ctttccatta tgaagaagcg aatgcgctgt acgaaaaaat ccaaaccaga
    48241 ttatagcaat cttcctgttg gattgtttca aacgacacaa tttttattgg acctccatac
    48301 atttttgacc cgttacttct ttcaatatgc ctttccttgg aatcaaaatg aaacgttggt
    48361 tttttatctt ttcatgatca gtaactttac attagataca cataactcgc atgtccagga
    48421 gtttttgata agcgaaaaat acaaagacga cgtagtagct caattgaatc gaacgtttaa
    48481 acaatcgata gaagaatatt tctcttttta tgtttttcca gaagagattt cgcaaaagat
    48541 tgcgttgaca gtgatgcaaa atcacgctca ttttgcctat tttagaggat ggatgaatat
    48601 ttttggccaa gaaggattaa aacagcggtt aactgaagta gaagataaac aattcctggt
    48661 tttatgtgaa agattggtca gacaaacatt tgctattgtt gattttactg aagtagacga
    48721 ggaaaatgcc cgctttgaat tatttgctcg ctatgcatct attttgcgga cgctgatcaa
    48781 gcagttagaa ttacgtctgc aaattgctta tgatcttcct tatgaaaggc taatggcgga
    48841 tatcgtgaaa gaaatcatcc aggaacaatt gctgaatacg atcaaatatg atttagtcga
    48901 atacgagaaa gaaaagcagt atgatatcat tttgactagc caattgaaag agtacccgtc
    48961 acagaagtcc gctaaagttt ttgtattcac tagcaacgaa tataattatg atttccccta
    49021 tttgaaccaa tttttaaaag aatgttattt agaaaaattg aatttaagga tgaataaaac
    49081 atgaaaatcg tgatcattgg tgcttcccat gcaggcatca cagctgccct aaatctaaga
    49141 aaacttcaac cgaaagcaga agttttactg atcgatgaag atcataaaga tggactaggc
    49201 tatgtttcaa atggaatcaa cctttattta aaaggaaaga tacgtagttt agctgaagtt
    49261 gcccataaca tgcggactct tcaagaaagt ggggcaaaac tgatcaccga atggagagta
    49321 actgaacttg atccagacaa acatcagctc atcctcgcat ccaaagaagg aaaaaacgag
    49381 accataacct atgataaatt aatcgtagca acaggttcct ctcctgtcac cttgtataaa
    49441 caaattgaag ctgaaaatgt ctacacctat aaaaatctag tgcaatctaa gcaagtactt
    49501 gccgctttaa aagaagcaaa agaagtagtg atcttcggtg ctggttatat tggattggaa
    49561 ttagcagatg ctttgagaaa taaaggatac attattcatc tagttgatta tatgccgaat
    49621 gttttatcaa gatatttcga taaggatatg atcaacagtt ttcaaaatca gctgcaaact
    49681 aagcaaatca atttttatcc aaatgaattc ttgatcgatt ggaaaaaatc agaagagaaa
    49741 gtagtatccg tacaacttct atctcaagca ataaaggcag atatggtcat tttttctgcc
    49801 caaactcgtc ctaatacgac attgttaaaa gaaaaagtgg ctttgtatga ggatgagact
    49861 gtgatagtca atgaatatct gcagacaagt gatccggaca tctatgcgat tggagatatc
    49921 gtcccagtca gttttgacaa aaataaacgg catctctttt tacctttagt tactcgagct
    49981 gtacatatgg caagagcagt agcgctaact ttgagtggtc agccaaccgc ttacgacctc
    50041 agacaaaaga taacagcagc agtcattata gactactttt taggaactgt agggctgaca
    50101 gaagatgaag cgccattctt ggaacaaaat accggttcgt gttcaggaga atttgatcta
    50161 tttccacaat acgatgaaga aaacaaaaca gtaaatgcaa agctgatcta ccatccggat
    50221 acattagaaa taattggcgg acagctgata agccaagaat tcttattatc agatttgaac
    50281 ctgcttgcgg atatcgtgaa acacaaaact acgattccac agctagcagt tgaggatttt
    50341 ggatttctgt ctgaacacac ctctcgtttt cactacctca atgagttagc ttttaaagta
    50401 ctagctaaga gagcaaatag caatagagta gataaaagac tgtgagaaat atcacggtct
    50461 tttattgtgt ggggatataa taaatattaa tcaatcgaga ataaaaaatt catataatga
    50521 aatagcggaa gaattttttg agcataatat tcgccaaaaa tttatcaagt gataaaattg
    50581 ttgtataaaa tgattatttc aggaggagga gttaaatgtt tttagcatta aatgaaatta
    50641 tgcattcaaa gttacgttat gcgttagttg caggggtgat gtttttgatc gcctacctgg
    50701 tatttttttt gactgggtta gcttatggct tagctcaaga taatcgaaca gcagtcgaca
    50761 agtgggaggc agattcgatt gtgctttcga aagatgcaaa ttcaaatcta gggatgtcca
    50821 tgattactaa gaagatagca gaagaagtcg aaggtgggaa agtggcgtat cttgcccaga
    50881 cacctggagt cgtgactagt aaagacagta cagaagaagg aaaaatcaat gttagcttct
    50941 tcggtatcga taaaaatcaa ttcatcatgc ccaatcttgt tgaaggaaaa gcttttgata
    51001 acgatgatga ggcagtaggc gatattagtt tgaaagaaga atatggtcta gccgtaggag
    51061 atacagttaa gttatctggt agtgacaaga cgtttaaact aactggcttt acggatcatg
    51121 ccaaattcaa tgtctcacca gttctctata caaccatcaa tgcttaccaa gagatccgct
    51181 tcgaaaaaga agatacaagt gaaaatgcac ggattaacgc aatagttgtc agaggtaaaa
    51241 tcagtaattt acctgaagat ttagaacaga tcaaaatttc taaattcatc aatgaattac
    51301 ctggatataa tgcgcaagta ttgacttttg gatttatgat cggatttttg atcgttattg
    51361 cggctattgt gatcgggatt ttcatttatg tactgacgat gcaaaagatt aatatctttg
    51421 gtgtaatgaa agcacaaggg atcacaggag gatttattgc gcgttctgta gtggcacaaa
    51481 cattcatttt atcatttgtt ggtattcttc ttggtctatt aggaacagtg ggaacatccc
    51541 ttgttctacc tgatgcggtt ccattccaaa gcaattggct gttttttggc gtcattagct
    51601 tgttgatgct ggtagtagct gtgttaggcg cactattttc tgttcggaca atcgtaaaaa
    51661 tcgatccgtt gaaggcaatt ggataagaag gaggaagagc atgaaagcaa tagaatttaa
    51721 agaagtagaa aaaagtttcc aagatggcga ccaagtagtt aaagcattga aagaaacaac
    51781 catgagtatc gataaagggg aatttgttgc aatcatcggt ccttctggtt caggtaaaag
    51841 tacttttttg actttggcag gcggattgca gacgcctagc agtggctctg tatttatcaa
    51901 tgatcaagaa ttcagtaatc aaaaagaaag tgaacgcgtt aaactacgtt ttaaagaaat
    51961 tggctttatt ttgcaagctt ccaatctggt tccttttctg acagtaaaaa agcagttatt
    52021 attagtagat aagatcaaac atgaacatcg tcaaaaagaa gcaaaagaat tatttgagca
    52081 gcttggcgtg gataagttga tcaacaagta tccagaagaa ctatctggtg gagaacggca
    52141 aagggtcgca atcgctcgtg cattgtacaa tgatccgtcc attattctag cagatgaacc
    52201 aactgctagt ttggattcag aaaaggcacg agaagtagtc gatatcttgg caaaagaatc
    52261 aaaagacaaa aataaagcaa cgatcatggt tactcacgat acacggctga ttgacaaatg
    52321 cgatagaata tttatgatgg aagatggtgt attgaaagaa aaagaataac caaaaagcag
    52381 gtggaaaaat ggtccatcga tacaacaaag atacacagca aaaaattttg aaagaagcga
    52441 ctgacttgtt tatgtccaag ggatatctcg gcacttcaac aagagagatc gcacaaaaag
    52501 ttgggatcac ccaacccaat ctctatcatt atttcggtga taaagaaaaa ctatatacgg
    52561 cagttttaga aaaccactta aaagatgttg gaaaagcttt gagagaaatc gttcaaacaa
    52621 gcgaaacggg atttcaagta accttgacaa aaatggcgca gtttttgatt gagacacatc
    52681 tggtcgattt gtttctgatg cttcacgatc ttgaaagcaa tctttcaaag gaaacaagag
    52741 atcatctttt ctttctatgg aagaaaaatt atcgtgaacc ttttgaagaa atcttttcag
    52801 caaaccaatc tgtgctaaga aatgggattt caaaagaaat cgcagcaagg cattttttct
    52861 tagtgttagc accttacatc actcggtcga aaagacctgt ggaagaaccg ctaaatgtgg
    52921 cgcaattgat cgatttatat ttgaatggtg tattaggaga agcgtaaagc tgttatatag
    52981 ggagaaaaat agttaggtga agaagcaaga tatgacgaag atcgttatat cttgtttttt
    53041 ttatataggt agtttttcat aaatacaaat ttgttattct ctcatgatta tcagggtata
    53101 tttttattta ttatgtcggt gttccaggaa gtgttttaat ttaataacga agaaattaat
    53161 tgtttgtaga atgaaggaaa ctatttattg ggtagatgaa tcaccacgaa tagtcaaaag
    53221 gagatttcag gatatgccaa aaatgaaaaa aatcatttta gcagtaatgt tattttctac
    53281 ggttatatct tttacagccc cttttttgcg tacttaagct gattttaagt tttgaccctt
    53341 agtctggatc tacgaggtga gagtcaagaa tgaaaaaaat aattggagct tttgtatttg
    53401 caatcattat cattattatc tgttttcaaa tagatgtttt tggtcaaaaa aagatagttg
    53461 gacaaacggt cagcagtacg aacagtacgg ttacaaagac aaaggaatca tttgatgata
    53521 cagaacaaga gacattaatc aaaatcggaa aaaatgaccg tacactatat acagatgact
    53581 cgctaactac cccacttgca actataaacg gcggagagct ggcggagttt ctttctgaaa
    53641 caaaaaatgc ttatcagatc aagacaaatg atggctatac tggatattta gccctcgaag
    53701 atggaaccaa agtcacaaag aatatacaaa caaaaccgga agagctatct gatgcagtga
    53761 ttgtattaga tcctgggcat ggcggaaatg atactggggc attaagcaat gatgaacaaa
    53821 cagaagaaaa agatataaca ttaagtacag ccataaaagt aaaaaaggcg ctagaggatg
    53881 ctggagcaac ggtttatttg acccatacta cagatgaatt agtacagctt ggagatatat
    53941 gcgactacag tgaagaaaaa aaggcagatg tctttatcag tttacacgca gactctacgg
    54001 aatatgcgaa tgaagcaact ggaatcacga catattatta ctatggacaa gaggaaacat
    54061 tagcacagac aattgctgac tccttcactg atctgcctct ggattcaaga ggaatctcca
    54121 ctgggaacta tcaagttctt cgagaaaatc ttcaaccttc tattttaatc gagatgggtt
    54181 atatgaataa tgatagtgat ttaaaggaat tagtaacaga cagttatcag cagcagattg
    54241 ctgcaagttt gacacaagca ttgaccactt attttcagta ataaataagc ccagccaaac
    54301 aaaaatagct cctcatattt ttcgtttggc cgggcttatt atcgcagatg caagcttttg
    54361 aacaccgttt aaggaagagg ttgtgagcct gccgtttaac tccgcgtcac aaggagcaat
    54421 ttcaaaaaac agcttctcat gtttgatgac tattgtgact tgtgaccgag gagttggcat
    54481 gagaacaccg tttattcgga acaagggact gtgacatgac ttttgtcaca gttccattat
    54541 ttttttagca gcttcaaagc tttttctgta ttggcaaaat gaagtttggc atatttttca
    54601 agcataggca tgccgccttt ctccaatagt tttgccgcta cttggtcaga tttcgttcca
    54661 gctcctgatg gaagggtgat tccagcttca gctgatgctt tgtgtaactc ttccaaaaag
    54721 ctggcacgac tgatgataga agcagcagca acagctaaat gatattgttc tcctttagta
    54781 acgaagtaca gtttttcttg taattgattt ttttctaaac gcgcatattt tttaaaattt
    54841 gcttccggcg taaactgatc gatcaaaatc gcttctggtt tttctggctc gatttttttt
    54901 agcagcaaat ggatcgcttg attgtgcaaa gcgactttca tccgaacggc attgtatttt
    54961 ggttggatct cattgtattt ttctggagat aagacaagca gtttataggg gatggttttt
    55021 tttaagatgt cagcaagctg gatgatttgg ctatctttta actcttttga atctctaaca
    55081 ccaagtttac gtaattctgc aagctgatca cgtttcacat aagcagcaca tactgttagc
    55141 ggaccaaaat agctgccatt tccgacctca tcactaccta aaacggataa ttgactgata
    55201 ttttttggca aagaagaggc tgtttttgct ggcttggctt gtttatcctg tgcctccccc
    55261 catttatcag cttctattgc tgcattcgta ccttgaaaca tcacttttcc ggatgtataa
    55321 gcggtaatgg tcgtcccgtc tttttttgca gcaaagctag tataaggaat ctgtttattt
    55381 aacaaataag agcgatagta tgctttcatt tgactaagtt ggtcgtttgt tgctttgata
    55441 atgacgttgc tcataaaatt ctcctcgttt ttatacataa aactataccg caactcacga
    55501 cttttcgttt tctaagagat tgcgagacat agcatttttt taaagtttat catataatag
    55561 ttaagtatgt gaaaaatatt tgtggagaac ggtgaaagaa ccaacttcat ggtacactaa
    55621 ataaaacttt catcaaatag gaggaaatga ttcgtatggc gcacgaaaaa acacgctaca
    55681 aagcagtgat tgccaaccaa acatatacta ttatcggacg ggaaaccaag catcatatgg
    55741 atatcgtaac gaagctgatc aatgaacagt tagcagaatt gaaacaatta tcaccacaaa
    55801 tggataatga acaagcagca atcttgatgg ctgtcaatgc gctttcggat caattgaaga
    55861 aacaagaaag aatcttggag ctggaagaag aaacagcaga attaaagaaa aaaatgatca
    55921 aatttacaga gcttgaaaat cgtgtgaaac gcattgaagc aatcgagaac gaagctcggg
    55981 aagtattgaa agaaaatggt caagcagatc ataccattaa aaatcatgtg gaagcacaac
    56041 agattttaaa cgagaaacga aaaggacaaa ttaaacaaaa atcttctaat taagatcctt
    56101 ttatcaaaat aagaaaaatt taaaaaagtt agaagagaaa ggaacgtagc atgctgagtt
    56161 tgctgatttt atttttattg ctaattgcgt ttttttctgg agcacgtcgc gggtttgctt
    56221 tgcaaatcat attcgcgatt ggatatgtat tgtcatttat tgctgcccag catttttaca
    56281 aaccattagc aagtcatttg gaattataca ttccataccc agctgtcacc ccaacatcaa
    56341 agttagcatt ttttgatcag gtatttgctt ttcacctaga tgaagctttt tatgcaggaa
    56401 ctgcttttct gattattttg ctaattggct ggctgcttac ccgatttgtg ggggtttttg
    56461 tccatggatt gacgtatgtg ccgatcttga gacaggtaga ctggattgca ggaggcatcc
    56521 tgtcactaat catggcttac gttactatat ttttgatttt gcagttactt gcctttgttc
    56581 cattagatgt ggtccaaaat caattcggcg agcatagttt cgctcgtttt atcgttgaga
    56641 gaacgccatt tcttaccaac aagatgtatg agctttgggt aacgaatatt ttgaattaag
    56701 gaaaatagtg ctggaaaata tttcgttttt tgtacagagt agtttattta agaaggctgc
    56761 gtagcgtatg tccggcacag ctcttttttc atagtgaaag ataaggtgat aaaatgaata
    56821 accgaatcct tgaaacattg gaatttgaaa aagtcaaaca gatggtcaga caatttgtag
    56881 tgactgcaca aggaaaagaa gaactggcag aattggtacc agtgagtgag aaacaaacga
    56941 tcacaaactg gcttcaagaa actgaggatg gattgaaagt gcaacgtctg cgaggcggga
    57001 tccctatacc taaacttgaa aatatccgtc cccatatgaa acggatcgag atcggagcag
    57061 acttgaatgg agtggagctt gcacaagttt ccagagtatt gtctacgaca agcgaattga
    57121 atcgtttcat tgatgatctt tctgacagtg aaatcgaatt tgcacgtttg tatatgtggg
    57181 cagatcagtt agtcacgatc cctgttttga gccgccgttt aaaggaagca atcgatgaag
    57241 acggacgcgt gactgatgac gcttctcctg agttaaagag cataagacag aacattcggc
    57301 gaagtgaaca agctgttcgt gaacagttag atgggatcgt ccgtgggaaa aatgcaaagt
    57361 atttaagtga tgcgatcatc accatgcgaa atgaccgcta cgttatccca gtcaaacaag
    57421 aataccgcgg tgtatttggc ggtgtagtcc acgatcaaag tgcttcagga cagactttat
    57481 ttattgaacc aaaacaagtg gtggatttga ataatcgttt gcgtcaatac caaatcgctg
    57541 aacgaaatga gattcaacgt attttaagtg aactttctgc tgaacttgtt ccccatcgtc
    57601 aagaaatcat ccacaatgct tatgtgattg gtaaaatgga tctgatgaat gcaaaagcac
    57661 gatttggtaa agaagtaaaa gccatcgtgc cgggaatcag tgaagacaat catgtcgtct
    57721 tgaaacaagc aagacatcca ctgatcgatc aggaaaaagt agtttctaat gacatcacaa
    57781 tcggaaaaga ctatcaagcc atcgtcatta caggacctaa cacaggtggg aaaacgatca
    57841 cgttgaagac tttaggtctg ttacaactga tggggcaagc aggattaccg attcctgcag
    57901 gtgaagaaag tcaaatcggt atttttgagg aagtatttgc ggatatagga gacgaacagt
    57961 cgattgagca aagtctatcg accttttctt ctcatatgac gaacactgta gatattttat
    58021 caaaagtcaa tgaaaaaagt ctggtattat ttgacgagct cggtgcagga acagatccgc
    58081 aagaaggtgc tgctctagca atcgcaatct tagatgatct tggtaaaaag tctgcttatg
    58141 tgatggcaac aacgcattat cctgaattga aagtttatgg atacaatcgg gcaaatacga
    58201 ttaatgccag catggagttc gatgtggata cactaagtcc aacgtatcgt ttgctgattg
    58261 gcgttcctgg acgaagcaat gcgtttgaaa tctctagccg attaggtctt gatacagaag
    58321 ttattgatga agcgaagcag ttgatgaatg atgagagcca agatttaaac gaaatgatca
    58381 cagatttaga gaatcgccgg aaaatggcag agaccgaata tctggaaatg cgtcattttg
    58441 tttctgaggc acaagaactt cacgatgatt tgaaagaagc ttacagctat ttctttgaag
    58501 aacgtgaaaa agaaatggaa aaagcaaaga aaaaagcaaa cgaagtcgtg tcagaggcgg
    58561 aagaaaaagc agaaaaaatc attgctgata ttcgtaaaat gcaacagcag attgggcaag
    58621 gaaatgtgaa agagcatcag ttgatcgatg caaagaccca attagcaaat ctacatcaag
    58681 aagaaacttt gaagaaaaat aaagtattga agaaggcgaa agaacaaaaa acgttgaaac
    58741 cgggagacga agtgttggtt acgacttacg gccaaagagg gacgctttta cgtaaaaacg
    58801 ggaatcagtg gcaagtagaa atcggtatat taaaaatgaa tgtgtccgaa gacgagctga
    58861 cgcctgttgc tcctcaaaaa gagccgacac aacgagttat ccatgctgta cgatctgaat
    58921 ctagtagtca cgtgccgaat caattggacc ttcgaggaaa acgatacgaa gaagcgctaa
    58981 gtgaggtaga tcaatatttg gattctgcca ttctagctgg ttatcctcaa gtgactattg
    59041 tccacggaaa aggaacaggc gcacttcgca agggaattac tgattatctt aaaaaccatc
    59101 ggagcgtcaa aagctttgag tttgcaccgg caaaccaagg cggaaatggt gcgacaattg
    59161 ttaaatttaa gtaaagctta ctaaaggtaa gcagatggtt cgctatccaa gtatagaaat
    59221 gctatactaa tcatagattt taaaaatgga ggtctttgat atgtcacaag taattacaga
    59281 taagacattt aatgaagaaa cagataaagg acttgtattg attgattttt gggcaacttg
    59341 gtgtggtcca tgtcgtatgc aagcaccgat tttggatcag ttggaacaag aatatgatga
    59401 agaagaattc agaattgcta aaatggatgt ggatgaaaat ccagaaactc ctcaacaatt
    59461 cggtatcatg agcattccaa cattaatgtt gaaaaaagat ggtcaagtag tagaaaaagc
    59521 tgttggtgtt cattcaaaag aacaactacg tcaaatgatc gatcaatatt tataaaaact
    59581 tacagcaaaa ataagctgag ggtgggactg aatccagttc cgtcctcggt ttttttgcgg
    59641 ttgagttaag gttattcaaa ttaatatttt ttgagtataa ttacgttgtc aggctggatt
    59701 gtttttttga cagacatgct ataataactt taattgaata tgaaggggag taccagatga
    59761 acgaacgaat caaaaacaaa ttagctttac ttcctgatca gcccggctgt tacttgatga
    59821 aagataaaaa tggaacgatc atttatgtcg gcaaagccaa aatattaaaa aatcgtgtcc
    59881 gctcatattt tactggcagc cataatacga aaacggaacg gcttgttagt gaaatcgaag
    59941 actttgaata catcgttaca gaatcgaata tcgaagcatt gctcttagag atcaatctga
    60001 taaagaaaaa tgatcctaaa tacaacatta tgttaaagga tgataaaacc tatcctttcc
    60061 ttaagataac gaatgaaaaa tatccccgtt tggtgattac tcgtaaagta ctaaaagaca
    60121 aagcactgta ttttggacca tatcccgatg tcggtgcggc gaatgagaca aagaagatcc
    60181 tcgatcgatt atttcctctg agaaaatgca aacctagtca gacgaaggag ccttgtcttt
    60241 actatcattt gggacaatgt ctgtgtcctt attatttcga cgtagatccg aaagtctata
    60301 cgaaaatcgt tgatgaagtg aaaaagtttt taaacggagg acacgaaaaa atcgagtcag
    60361 agatccatca gaaaatggaa aaagctgctg aaaacatgga gtttgaaaaa gctgcagaat
    60421 accgagacca gatccgtgcc attgagacaa tcatgactcg ccaaaaaatg acaaatactg
    60481 atttactgga tcgagatgta tttggttatg cgattgacaa aggatggatg tgtgtccaag
    60541 tgtttttcgt aagacaagga aagctaattg aacgagatgt ttcaatgttt cctttctata
    60601 acgaagcaga agaagatttc ttgacttacc tcggtcagtt ttatcaggaa aatgagcatt
    60661 tcattcctaa agaagtcttg attcctgata cgatcgacaa gcccagtgta gaagctttgt
    60721 tagctacgaa agtgctgcaa ccaaaacgag gagaaaagaa aaaattagtt gaattggcga
    60781 ataagaatgc ctcagttgct ttgaatgaac ggtttgatct gattgccaga aaacaggaac
    60841 ggacgatcgg agcagttgaa cgtttaggaa acgcgatgaa tatcccgacc ccaatacgta
    60901 tcgagtcttt tgataactct aatatcatgg ggacgaatcc tgtggctgcg atggtcgtat
    60961 tcattgatgg aaaaccggca agaaaagaat atcggaaata taaaataaaa acagtcaacg
    61021 gaccggatga ttatgcatca atgagagaag tcatctatcg cagatattca cgagtgattc
    61081 gcgaagggtt gcctttacct gatttgatct tgatcgatgg aggaaaagga caagtagatg
    61141 tggcaaaaga tgtcttagaa aatcaattag gaatcgatat tcctattgct ggcatggcaa
    61201 aaaacgataa acataaaaca aatgagttgc tattcggtat agatttggct gtagtaccgc
    61261 ttgagcgaaa ttcaccagag tttttcttac tccagcgaat ccaagatgaa gtccatcgat
    61321 tcgcaatcac tttccatcgg cagctacgca gtaaaaacag ttttgcttcc cgattagatg
    61381 aaattgaagg gttaggacca aaacgaaaaa aaatgctgct taaagagttc aaatcgttga
    61441 aaaatatcac agcagccacg acagaagaat tacaagaaat cggactgccg aaaaatgtcg
    61501 cacaaaacgt atttgataaa ttacatcagg aatgaggaaa gggcacttta caaagaaagt
    61561 aaagtgtcct atcattttat gtacaacaaa aagagcgttt acgttttgtt ggtaaataat
    61621 aaatcgctta cgtctggtgt ctaaggatat atgtgatttc ttgaagaagg agtgaagaaa
    61681 tgttagaagt caaggatctt gttaaaactt ttgggaacta cacagctgtc gatcatgtct
    61741 ctttccaaat ccccgatgga aaaatcatgg ggctaattgg ccaaaacggg gctgggaaga
    61801 caacgacttt tcgtttgatc ttggattttt tgacacaaga ccaaggagaa gtgttatgga
    61861 atggccatca tcttggggag aaagattatg atgtcatcgg ttatcttccg gaggaacggg
    61921 gactttatcc gaaagtaacg attcaagacc aactgcttta ttttgcagaa cttagaggga
    61981 aatcaagaaa agagattgaa ccaaaaatcg atttttggat ggaaaaattt caggtaaaag
    62041 ggaaaaagac ggataaagta aaatctttgt ctaaaggaaa tcagcaaaaa gtccagctga
    62101 tcgccacgtt aatccatgaa cctaaattga tcattttgga tgagccattc agcgggttag
    62161 atccggtaaa tgctgaattg ctaaaagatg gaatattgga attgaaaaaa catggttcat
    62221 gtgtcatttt ttctagccac aatatggata atgtagaaaa aatctgcgat catttgatca
    62281 tgttgcgaaa cggaaaaatg gttttgaatg gaaaagtaca tgagattcgt gaatcatttg
    62341 gccgtacgaa gttattcttg gaatctggtt taagccaaca ggaagtagaa gaaatcgaag
    62401 gcgtgaaaaa agtgatcctt catgaagaca atacgttaga gattacctta gaagatcctg
    62461 aagctgggaa agaaatcttt actcgtgcga ctcagttcgg ctacattcct atgtttaacc
    62521 agcaaccgcc aactttggaa gagattttca aattgaaagc aggtgaaatc gatgcgtaag
    62581 ttttggatta ttaccaaaga tgtctattta aaaaatgtta agtcgatttc tttcttgatc
    62641 atgatattag tcccttttat catgctgggt atcatttatg tagcaggaaa ctttgctcaa
    62701 caaaatagtg atgtcaataa aatcggcgta ttggctgata atgagcaaat cagtcagcaa
    62761 atgagccaag tcaaaacaga tgattttgag ttcaaagcag ttgattctga agaaaaagca
    62821 caaaaagagc tttcggaaga aaaaatcgat gcgtatttag tagtctcaac tgagaatgat
    62881 aagataaatg ggatgcttta tagcgaaaat tcattaggac aaagtacaca actactgata
    62941 caacaacaac tgactggctt gcaatcgatg cttcgagcaa gtcaattagg catttcacca
    63001 gaagaagtag ctagcttgag ccaacaagca agtttgactc gacaaaaagt caattttgat
    63061 tcaaaaggaa aaatgacagt tggagaagat aactcgacag tccaatatgt cgtaagttat
    63121 gtagcaacga ttgtcttgtt cattattatt ttgacgtatg cgcagatcat tgcacaagag
    63181 atcgcttctg aaaaaggcac gcggatcatg gaagtgatcc tgtccagtac gactgcacaa
    63241 aagcattttt acggaaaact aacaggtgtt ttacttgttg cattaacgca aatggcatta
    63301 tacggtatta tttttggtat aggatacagt caattcaaag atatggaaat ggtcaaaaat
    63361 atattagacg gtatctcatt ggataacttg attggaccat tcttgtggta ttctcttcta
    63421 ttcatgatct ttggcatttt gattttttct gttttagcag ctttatgtgg ctctttggtc
    63481 aacaaagcag aagatacagc aaaagcaatt ttgccagtga cttatctatc tctaggcgga
    63541 tatatgcttg gattgatact aggagcttca gatccaaaca atatcgttat tcggatcact
    63601 tcgtatattc cattcttatc ttcatatatt atgccggttc gcttagcaaa tgagacagtc
    63661 ggtatgggtg gagcattgat ttccttgttg gtacttgtag ccgtaacatt cttattgatg
    63721 atcttgtctg caaacatgta caaatcgaat gtactcgtgt atagcgaagg cggattatgg
    63781 agttcattga aacaatcgat ttcaattatg agaaatgaac gaaaaaaagc ataaaatata
    63841 gaaaaatata gaaggaagct ggacatttat tgttcccagc ttcttttttg tatagaccta
    63901 tttctatttt tttattatat tggatatata tattcattga aaatagagca taacaacttt
    63961 ataatgttga gtataccaat ttttggaggc gttttaatgg accgctattt agatttactt
    64021 tcagagaagt tccctacaac ggaagatgtc atcacggaaa tcatcaatct cgaagcaatt
    64081 ttgcagcttc caaaaggaac agagttattt ttgagcgata tacatggcga atttcctgct
    64141 tttgatcata ttctgcgtat cggttcagga aatcttaaag aaaagatcaa agaccttttc
    64201 tctgaacaaa tgacggaaac ggagatcagc caattcacta tttttacggc ttatccagaa
    64261 tatgtgttga cgactgattg gtacaaaaaa caagataaat cccagctgat ccatcgtttg
    64321 atcgatcttt tacggtttac gacagtcaaa tacactcgat caaaagttcg aaaaggattg
    64381 ccgaaagaat atagctatat cattgaggaa ctcttgtata tcgatgatcg tatcaacggg
    64441 aaaaaagact atgtaaaaaa aatcattgaa caacttgtct tgatgaagga agaagaaaaa
    64501 tttttaacaa aacttgcgca gacgatccaa aaatctgtca tcgatcattt gcatatcgtg
    64561 ggtgatattt ttgatcgagg aactcaagca gccaaagtaa tggatcgaat catggatttt
    64621 tcctctgtag atatccagtg ggggaatcat gatattttgt ggattggtgc gtattgcggc
    64681 tctgaggcat gtttattgac gcttttacgg attgccgcac gctacaacta tttatttgaa
    64741 ttagagaaag aatatggatt aaatttacgt ccattatttt cttttgccca tcaaacctat
    64801 cagaagaatc cagtatttac ccctaaaaac aggaaagatc tatctgaaag agagcaagaa
    64861 gaattagaaa agatccatca agcactttct atcctccaat tcaaatcaga acatcagttg
    64921 ttgaatcgac gacctgaatt taaaatggac gatcgtaaat tgttggaaaa aatcaactat
    64981 gaggaatcaa cgatcgtttt agaaggtcag ctctatgagt tgaaagggac ttgttttcaa
    65041 acgatccagc cagatgatcc taaaaaattc ttggaagagg aacaaaaagt gatcgatagt
    65101 ttgatgtatt cattccagca ctcgttaaga atgcaaaaac acatgacgtt tttgatcgaa
    65161 aaagggggaa tgtatctcac gaacaatcag catgtactgt tccatggctg tatacctgta
    65221 gatgaaaagg ggcagctctt agcatttgaa ttagaccaat cttatcgcgg aaaagaactg
    65281 ctgggatttt ttgaaaaaca gataactgaa agcgcaaaag atttgactgc aaatgaagat
    65341 ttggcgaccg atttgatttg gtatgcgtgg agcgggccat tttcgccttt attcggcaag
    65401 agtaaaatgg caacttttga gcgctatttt ctcacagagc ctcatacgca cgtcgaaaaa
    65461 agcaatccct attatcactt gcgagatgaa gagtggttca gtgaaaaaat tttggcagaa
    65521 ttcgatgcaa aagaagaagg ttcagcaatc atcaatggac acacgccagt aaaagtaaaa
    65581 aaaggagagt caccgatcaa agcaaacgga aaagcatttg ttattgacgg aggtctatcc
    65641 aaagcttatc aaaaaacaac cgggattgct ggctactcat tactatgcaa ttcttacggt
    65701 ttccaaatcg tgacacatta tccgttcttg cctattgaac aacaatttgc aaaaaaatct
    65761 gatcaaacga atgtaaaaaa agtgatcgag cagcagctcc cacgcaaact taatcggaat
    65821 acgacaaaag gaatggaatt acagcaacag attactcaac tccaaaggct gttggattat
    65881 cgaaaggacg attgagaaaa atgctagcca acattgctca atagactaaa aagcgactgc
    65941 aacaaaaggc gtgtcgcagt ctccttcgga attagctcaa aaaacggtaa aatattagaa
    66001 gctatttttc tgtttatttc tctaatactc aggtcagggc gctgatttca cgacctcttc
    66061 cttaaacggt gttctcctgc caactcctcg gtcacaagtc acaatatcca acaaacatga
    66121 gaagctgttt tttgaaattg ctccttgtga ctcagagttg aacggcaggc tcacgaccta
    66181 atcagaaaaa cgattaaaat tcattcacaa agaaatcgaa taaacgctgt tcagatgaat
    66241 ctacacgatg agaaagttcc ggatgccatt ggacaccaag gattttgtgc atattatctt
    66301 tactttggac tgcttcaatg agtccatcgt tggaaaaggc gatggctttt aacaaaggag
    66361 aaagatcttt gactgcctga tgatgatagg aattcacaaa gtatgaatca gggagaaggt
    66421 cacttaataa actgtccgaa acgattttga cttcgtgagt tgcaaactgc ggggcagtgg
    66481 gctgttgttc gtgttttacg gaccattttg gatataatga aagatcttga taaagtgttc
    66541 cctccaacac gacattcaat agttgaagtc ctcggcagac tgcaaaaatc ggttttcttt
    66601 gtttcaatgc ttccaagatc aatgcctgtt cgaattggtc tcgttgaata tttgtttccg
    66661 tcagttttgg atgagggtct tccatgtaaa gttgcggact aacatcctga ccgcctgcaa
    66721 gaatgagttt gtcgattttc tcaattagtt gaggcgctga atctggagac atgactggca
    66781 gaataagagg taatccttga gcatctaaaa ctgcatccac aaatccctgc ggtgtatagc
    66841 ttacttgatt tccttggaaa gtatctgtcg ctcgaatcag ttgattcccg gcaatgccga
    66901 tgattggttt catttttatt ccccctaaag tagactaatt gtaacaagga tttaaaaaaa
    66961 tttaaactat gtaagacttg cccctatact tatctgttct tgctgtgtta ctatctgtaa
    67021 agagaatttt cgtgtgaaat tcatgacgat agttgaaaat attgcttaat ttgttataat
    67081 aaaaagtaag cagaaataaa aaggttgggc gtaagcttca aggatctagt tcttcaaggg
    67141 gtgagaagga cattttattg aaggggcctg cctatactaa gttatcttta gaggtacata
    67201 ctttcaatga aaaaagaaag catgtacctc ttttttaaat cgaaaggaag tgaagcaagt
    67261 gttagaagct ttggaacaaa tccgaaaagc agaagaagaa aatgagaagc gtgctcgaac
    67321 cctacggcag cagttgaaga cctatgcaga agaaaaagag caagaattgg agataatcca
    67381 aacgaacagt cggcaacagc tgaaacagtt ggtagaagaa aaagaacaat tcgaaaagca
    67441 agaattagaa aaagaaaaaa tgaaattgaa agcagaagca gacaaggtgc aagcaacttt
    67501 gaaagaccaa tatcaaaagc atcagagtca agcaatcggt gcaatcattg aaagggtgaa
    67561 agaaacttat ggccgtcact aagatggaaa aagtgaccct catttcagat aaaagaaatc
    67621 aggagaggat tttacaagca gtacaaggaa tccaaaatgt tgaaatccgg gatctgtatc
    67681 aaaatagaac aaacaaccag tgggtagaaa aatattttcc agataccacg attattgata
    67741 aagaagcaaa attaagcgct ttaggcaatc ggctgaaaga catccaagaa gctatccaat
    67801 tcatacaaca ccacggcgat agccgtcaaa agaaactcca tttgaaacgt caagaacttt
    67861 ccttacaaga cttggaagca aattattccg aagaaaattt catgaataaa ttagaagaag
    67921 tccttgattt aaaagaaaag tgggaacagc taactgaaaa acgtgatcgt ttagaagaag
    67981 aggaagaatg gcttcttcat tggcaacagc tggatattgc tccaagtatg tatgcaagta
    68041 agacgaccat ttttgagatg gggactgtga gtgcagcaaa ttttgaaagt ttcaaggaag
    68101 aactaagtaa gcttgatgac gtttatatgg aagaaataga ttatacgcca aaacaagttt
    68161 atctttcgta tgttgcttta aaaaaatcag ttgctgctat agaagaaatt gctgggaaat
    68221 acgggttcaa taaagaaacg tatccttatg aacaaaatcc taaagaaaaa ttgcaagaaa
    68281 ccaaacagca attatccatt gttcacgagc agcaaaaaaa gataacgaca gcgttaggtc
    68341 agtgcagcgg ctatatccaa gaatttgaat gggtagaaga agtcacactt gccgttgcag
    68401 aacgggaaaa agtaaaagaa cggtttatcc atgccactta tctgatcgtt ttgcaaggtt
    68461 gggtagatgc agaagaaaaa cagaatttga tgcatgtgtt aaacgaaact gtatcagaag
    68521 aagatatata cgttagtttc gaaacaccaa actcagaaga gattcagcag gaagtcccta
    68581 ctaaattgaa aaaccatccg cttatcgaac cttttgaatt gctgactgaa atgtacagtc
    68641 tgccaaaata tgaagaagta gatccaacgc cttggatgac accattttat cttgtcttct
    68701 tcgggatgat ggtcgcagat gttggttacg gattgctgat gctcattggg acaatactag
    68761 ctcaaaaact atttgtttta ccccgcggga tgaaacgttt cgtaaaattc tttgagattc
    68821 tctcggtacc atcgatcatc tggggattga tctacagttc atttttcgga caggcattac
    68881 caaaagaact atttggtatc cgcttgcctt tcccaatcct atctacgacg gatgacgtca
    68941 atacgatttt gattttatcc gtgattttcg gtctgataca gatcttggtt ggattattcg
    69001 tggcagcaaa ggaaaatatc aggaggaaag attacttgag tgctgtcagt gatggttttg
    69061 cctggcaagg gatcctgatt gggatcgtta ttgcattgat tggtgtcatg ttgataaaaa
    69121 atacagcatt tgtttatctt ggcgcggggc tatcgatcat tgctgcttta tgtatcttaa
    69181 tcgtgccgat tatccaatcg ccgtctaaag tcaagggtgc tgccaaagga gcgtataatc
    69241 tttacggatt gactggttat atcggtgatt tagtcagtta tacacgtttg atggcactag
    69301 gtatttcagg cggaagtatt ggcgcggcat tcaatatgct agttgctttc atgccgccag
    69361 ccgctcgatt cagtgtaggg atccttttga tcatcgcttt acacgcactg aatatgtttt
    69421 tgacactgtt aagtgcctat gtccatggtg cacgattgca gtatgtcgaa ttttttggaa
    69481 aattttatac aggaggcgga cgtgcctttg acccgctgaa aacggcggaa aaatacgtca
    69541 acatcaatca taagaaaaaa aacaataaat aattggagga tttttataca atgatggatt
    69601 acttaattag tcaaaatggt ggaatggtat ttgcagtatt agcgatggca acagcgacga
    69661 ttttttcagg gattggttca gctaaaggtg ttggaatgac aggtgaggca gcagcagcgt
    69721 taacaacaag tcaacccgaa aaattcggac aggctttgat tctgcaattg cttccaggta
    69781 cgcaagggtt gtatggattc gttatcgcct ttttgatttt tatcaactta ggaaatgata
    69841 tgtcagttgt acaaggattg aactttctag gcgcttctct gccgattgct tttacaggtt
    69901 tgttttcagg tatcgcccaa gggaaagttg cagcagcagg tatccaaatt ttagcgaaaa
    69961 aacctgaaca tgctacaaaa ggaatcattt ttgctgcgat ggttgaaaca tatgcgattt
    70021 taggtttcgt tatttccttc ctattagtat tgaatgccta agcataaagg aggaaaagca
    70081 gatgaacgcc attgaaaaaa tcatctctca gatgaatgaa gcagcagagc aagaaagagc
    70141 ggcgttagag caagaagagc gaatgaagat cgatcaaaac tttgaacaaa aacgtacgca
    70201 aatcgaaaca gaacatcaaa aacaaaaaga aaaacaaatc gaattacttg aaaaaaaata
    70261 ccgtcagctt aggaatcgcc aacaagtaga agtacgacaa gaaaatttga atgcgaagca
    70321 ggaattttta cgacgattgt ttgcagatgc aatagctgaa atggagaatt gggatgaatc
    70381 tgaacaaatc cagtttatca aaaattcatt gtattcatta cctttgacag gcaaagtaac
    70441 attcattgct ggagaaaaat cagcagctta tctttctcag acattgctgg atgaatggaa
    70501 caatgaactt ccctttatga tggttttaag tgatgaaact gttgctgatc aagcgggttt
    70561 tctgataaac gatcaaggag ttcagtataa ttttcttttc agcagccttg tacaagatat
    70621 ccaaggaacg atgagttttg agattgccaa tcaattattc gaataaggag ggatcagtgt
    70681 atggaatacc acgaactaaa tcccttgatt cgcggaagag agcttgaact tttgtccaat
    70741 gagacatttg aacggatgat tcaaacaaat tctgtcgaag cacttggtga aatattgaaa
    70801 tccacgattt acagtccata tatttatgac ggatatgaat atgacttcga acagaatctt
    70861 ttaaaggagc agagccgtct atttcgctgg ttaaaggaat cagcaccgga gcctgaaatc
    70921 gtttggatct atacgatgcg ctatactttc cataatctga aggttttgac aaaagccgag
    70981 atgacaaatc aaaatctgga ccatttgtat atcgacgatg gattttattc attagaaacc
    71041 ttgaaggatg ccattcatac gcaagtttca aatgaactcc ctgaaagcat tatggacagt
    71101 atacgagaag tacgtgatta ttttgaagag tctaccattc ttcagggaat tgacgtgatt
    71161 tatgatcgac agtttttgac agagcagcga cggcttgccg ataagctagg atatcaagaa
    71221 ttgctgacag aagtcattgc ttttattgac ttgaccaata tcacaacgat ggctcgagga
    71281 atattgcaga aaagaacata tgggttcatg acgacggtac tttccagctc gggaagtatc
    71341 gaaaaagaag tatttttgaa ctttgtagat aaagatatgg aagattacac gaattttcta
    71401 ttagagacag attatgctga ttttctgcgc cctgtcatcc gtgagggaaa tcttgatctc
    71461 gtaaagcttg aacagttgaa agatgattat ctaagttcat tgtatcaaga agcacaaacc
    71521 caggctttcg gaccactgcc actactagcc tttttgaacg caaaagaggt agaaagcaaa
    71581 aaccttcgtt tactggttat cggcaaaaga agccatttcg aaccagaaac aatcagaaag
    71641 cgggtgagac aagtctatga cgcataagat cggtgtagtt ggcgacaaag attctgtttt
    71701 gccattcaaa ttgtttggct ttgatgttcg ttatggtaca accaagcaaa ccgttcgtca
    71761 ggcaattgaa gaaatggcaa agaatgagta tggcgtgatt tatgtcacag agcaatgtgc
    71821 agcattgagc ccagaaacga tcgaacgtta caaggaacaa atgatacctg ctatcgtatt
    71881 gattcccaat catcaaggat cattagggat agggctggaa gaaattcaaa aaaacgtaga
    71941 aaaagcagta ggtcaaaata tcttatagta tgaaaaggag atagaaattt tgcaaattgg
    72001 aaaaatcata aaagtctccg gacctcttgt aatggctgag aacatgtctg atgccagtat
    72061 ccaagacatg tgtctagtgg gagatctagg agttatcgga gaaattatcg agatgcgtgg
    72121 cgatgtggcg tctattcaag tatatgaaga gacttctgga attggtccag gcgaaccggt
    72181 tcgctctact ggtgaagctt tatctgttga attaggacca gggatcattt cacaaatgtt
    72241 tgacggaatc caacggccat tagatacctt tatggaaatc acacaaagta atttcttagg
    72301 gcgcggagtt caattgcccg cattggacca tgagaaaaaa tggtggttcg aaccaacagt
    72361 agaagccgga gaaacggtga gtgctggaga tgttatcggg atcgtagaag aaacaaaagt
    72421 tataaaacat aaaatcatgg tgccaaatgg gataaaagga acgatcaaaa caatcgaaaa
    72481 aggttcattc actattgatg aaacagtatg tgtcattgaa accgaaaatg gtgacaaaaa
    72541 tttgacgatg cttcaaaaat ggccagtaag acgtagtcgg ccaatcaaag aaaaattaaa
    72601 cccggatgca cccatgatca ctggacagcg agtgattgat acattcttcc cagtgacaaa
    72661 aggaggagca gcagctgtac ctggtccttt tggtgcaggg aaaacagtcg ttcagcatca
    72721 aattgcaaaa tgggccgatg tggacatggt tgtctatgtg ggatgtggcg agcgtggaaa
    72781 tgagatgacg gatgttttaa atgaattccc tgaattgatt gaccctaata caggagaatc
    72841 gttgatggaa cgtacggtat tgattgctaa tacatcaaac atgccagtag cagctcgaga
    72901 agcttctatc tatacgggaa tcacaattgc ggaatatttc cgtgacatgg gttatgacgt
    72961 tgctatcatg gcagactcca cttcacgatg ggcagaagca cttcgtgaga tgagcggacg
    73021 tttggaagaa atgcctggtg atgaaggtta tccagcttat cttggttcac ggcttgcgga
    73081 atactatgaa cgatctggaa gagtcattgc attaggatca gaaggtcgcg aaggaagtat
    73141 aaccgcaatc agtgctgtat ccccgtctgg aggggatatt tcggaaccag tcacacaaaa
    73201 tacattgcgg gtcgtaaaag tattctgggg tcttgattcc agtttagccc aaaaaagaca
    73261 ttttccttcg atcgattgga tacaaagcta ttctctttat tcaacagaag tagggaagta
    73321 tatggatcat atccttcaag ctgactgggc atccatggtc accgagggca tgcgtatttt
    73381 gcaggaagaa cagcagctga atgaaatcgt gcgtttggta gggattgatt ccctttcaga
    73441 taatgaccgt ctgacattag aagtggcaaa atccattcgt gaagattatt tgcagcaaaa
    73501 tgcttttgat gatgtcgata cattcacttc aagagagaaa caattcaaaa tgttgaagat
    73561 gatcttgacc tttggtgaag aaggacgccg tgcgttgtcg ttaggtgctt atttaagtga
    73621 gatcatggac ggtaccgtat cgattcgtga aaggatcgga cgaagcaaat atatcccgga
    73681 aacagaatta gaaaaactag atcaaattat tggtgaaatc aagcaaacga tgcaaacgat
    73741 cgtttcagaa ggaggcatga gcaatgatta aagaatatcg tacgatcggt gaagtcgtcg
    73801 gtccattgat ggcggttgaa aaagttgctg gtgtcaaata tgaagaatta atcgaagtcc
    73861 gtatgcaaaa tggcgagatt cgtcgtggac aagtattgga agtccaagaa gataaagcaa
    73921 tggtccaaat attcgaagga acaagtggta tcaatttacg tgactcttct gtacgatttt
    73981 taggccatcc tttagaacta ggtgtatcgg aagacatgat cggtcgagta ttcgatggtt
    74041 tgggacgacc gaaagataac ggaccagaga tcctgcctga aaagcatttg gatattaacg
    74101 gagaagtaat caatccagta gctcgggatt atccagatga gtttatccaa acaggtatct
    74161 ctgcaatcga tcatttgaat acattagttc gtgggcaaaa attaccagta ttttctggct
    74221 ctggtcttcc tcataaagaa ttagctgctc agatcgcgcg acaagcaacg gtactcgatt
    74281 catcagatga tttcgccgta gtctttgctg ctattggaat cacttttgaa gaagctgaat
    74341 ttttcatgga agattttcgt caaacgggcg caatcgaccg ttctgtcatg tttatgaatt
    74401 tagcaaacga ccctgcaatc gaacgtatcg ctactcctcg tatggctttg actgctgcag
    74461 aatatcttgc ttatgaaaag ggaatgcatg ttttggttat catgacagac atgaccaact
    74521 atgcagaggc attgcgagag atttctgcag cacggcgaga agttccagga agaagaggat
    74581 atcctgggta tctttacacg aacttagcta ctttattcga acgagcagga agaatccgcg
    74641 gactaaaagg atcggttact caaattccga ttctaacaat gccagaagac gataaaactc
    74701 atccaatccc tgacttgact ggttatatta cagaaggaca gatcatcttg actagagagc
    74761 tttacaagag tgggattcag ccaccaattg atgtactccc gtctctttcg cggttaaaag
    74821 ataagggaac tggacccgga aagacaagag aagaccatgc agctacgatg aatcagcttt
    74881 ttgcagccta tgcacaagga aaacaggcaa aagaattagc cgtagtttta ggtgaatctg
    74941 ctttatctga tgtagacaag atctatgcga agtttgctga gcggtttgaa aaagaatatg
    75001 tcaatcaagg attctacacg aaccgttcga ttactgaaac acttgatcta gggtgggaac
    75061 tgctatcgat gttgccaaga accgaattaa aacgaatcaa agacgacatg ctggacaaat
    75121 atctgccaga agggaagtga gttctgatgg cacgattgaa tgtgaatccg acccgcatgg
    75181 aattgactcg attgaaaaaa cagttgacaa ctgccacaag agggcataaa ttattaaaag
    75241 ataagcaaga tgaactgatg cgtcaattca tcctgttgat tcgaaagaac aaccagctgc
    75301 gtcaagaaat ggaagagtct atgacagaag caatgtctga ttttgtattg gcaaatgctt
    75361 cgatcacgga acctttcatc gaagaattat ttgttttgcc ggcggaaaac gttgatttgt
    75421 ctatcgtaga caaaaatatc atgagtgtaa aagtacctgt gatgaatttt gaatatgatg
    75481 aacagctgac agacacacct ttggaatacg ggtatttgaa ttccagtgcc gaactggatc
    75541 ggtcaatcga tcggtttact accctgcttc caaaactttt ggaactgaca gaaatcgaaa
    75601 aaacttgtca actgatggcg agtgaaatcg aaaagacacg tcggcgagtc aatgcattag
    75661 aatatatgac gatccctcaa ttagaagaaa cgatctatta tattcgtatg aagctggaag
    75721 aaaacgagcg cgcagaagta acaaggttga tcaaagtaaa aaatatgggt accactgact
    75781 aagtggtatc tttttttaaa agaggaaaac gatgattaaa caaagcaaac aaataaagaa
    75841 acgtttgccg gctgttcagc ttctcgcatt aggatttttt ctcctgattt tagttggcgg
    75901 cggcctactt accctaccat tttttagtaa tagtgggcat gggacaaatt ttatcgatgc
    75961 gcttttcact gcaacttctg ctgtctgtgt aacgggattg acaacattga atacagcaga
    76021 gcattggaac agtgctggtc aatttttgat catgcttttg attgagatcg gcggtcttgg
    76081 ttttatgatg gttccgattc tatgctttgc attgataaag aagaaagtca gtctcagcac
    76141 acgtattata ttaaaagaag cgctgaatct agaagaagta tcaggtgtga tgaagctcat
    76201 gctttacatc ctaaaattgg cctttgttat ccaattgatt ggtacggttg ctttatcttt
    76261 tgtatttgtg cctgaatttg gctggttgaa aggtatctgg tacagtttgt tccatgcaat
    76321 ctctagtttt tgtaatgcag ggtttgattt gttaggagac agtttagcca atcaccagca
    76381 aaatgtttat ttgatcatgg tggtatctgc tttgatcatt tctggtgggt taggcttcat
    76441 cgtatggcgt gatttactgg aatatcatca gaaaaagaag atgacgattc attcaaaaat
    76501 cgcattaacc gttacaggta cccttttatt aggcggattc gttgtgttct ttttcacaga
    76561 gcgcaatggg gcaacgctag tggaagggaa tatgtttcaa cgattggcaa acaccttttt
    76621 tatgagtgtg acacctagaa cggctggata ttattcagtt gattacctcc atatgagcca
    76681 tgcaggtctg attttaacga tgtttttgat gtacatcggc ggaacatctg ggtcgacggc
    76741 cggcggattg aaaacaacta cgttaggtgt gttgctgatc cagatgcgtt cgatgttgaa
    76801 aggacgtacg agagcggaag catttggccg taccatccga caaggcgcag tgttgcgggc
    76861 acttacttta ttttttgtta cgttgacgtt gtgtgtagtc gccatcatga ttttatcggt
    76921 gactgaaacg atacctaaaa cttctggcat cgaatatatt gcttttgagg tcttctctgc
    76981 gtttggtaca gtaggtctta cgatgggatt gacgccagac ttgactgcaa tagggaaatt
    77041 gatcattata gcgcttatgt acattggacg agttggtgta ttgactgtgg tcttctctct
    77101 gatgacaaaa gcacaaagaa cacaatcaaa atacaaatat ccagaagaaa gtgtcatgat
    77161 tggataattt catcttctga cagaaaccta gtgatttagt aaaataagaa aataaaataa
    77221 tttttcttgc ttcttggata ctttaagtgc aaaatgttcg tttatttttt gaggcactac
    77281 ccgttgttga acctcgggta gtgcctcttt tttattgaaa ggaatcaata agatttgatt
    77341 cctttattta tcaataggtt ataattcata tttttttatt ttttctttta cgatacttag
    77401 tccagaagct aaaatttcaa ggttattaga ggatagggaa attcgaacga atgcatctgg
    77461 ttgcgcacgt gtagtaaagc gtctggaatg ataaagtcgg ataccgttag caagaaagtc
    77521 attctcaatt atcttagggt caatctcagg atcaactgga agaattcgat agtaagggac
    77581 acgattcgtt ggtttttcta ctttgaaaag agaatcaaaa agctgattgg ctctttttgt
    77641 aagacttaat ttagtttcta agatcctatt tgcttcattt gaatggagga tttgagtgat
    77701 gacttccaca tctaatccag aagttttcac atttatatta aaaattgctt gttctatctt
    77761 gctttggaca tgtactggaa ctacaagata agcaactcgc aatccagaac aaataaattt
    77821 tgtcattcca gctaagtaga ttgtttggtt aggtaataaa ttttggaaag gaggaatgat
    77881 cgtatgttga tagtaagttg ttaaaaatga atggatatca tcttcaataa cccatagacc
    77941 ttctttttca atcacttcgg ctaattgctc tcgtcttttg tgagagattt gaaaccctat
    78001 aggattatta caagaaggca taagaaagac accatgaatc ttcttttttc tacattcctg
    78061 aatcaatata tcaggtcgca ttccttgctc gtcaaaatca attggaacga tctctaaatg
    78121 atataactga gccaattcaa tgaaattagc gtatgtatat cggtctgttg ctattctatc
    78181 acctggagag aaaagtgcag aaagtgtgat agccaatcca ttttgaacac cggaaacaat
    78241 agatagagat tctaaggacg gaatgactcc ttgagttttt aaccaatttg ctgcagtagt
    78301 caattgaaaa tttgtgcctt tgggatcttg gtaattaagc aaaccaacaa gatttgggtt
    78361 attactagtt gattgaataa acgggacaac gaatttatta cattcttcaa aagaactaac
    78421 cagaccaaaa tcaatgatat gttcggttac ttcattggta gagatggtga tggactcaaa
    78481 gacattggga gaaataaatg tgccacttcc aatattcgta tacagcaaac ctttctcaat
    78541 tccatattta taagccttgc caacggtagt aaaatttaaa tctaaataat cagctagctc
    78601 tctttgggag ggtaactgag tgtttttctg taatttattc tttaaaatat cttgttctaa
    78661 ttgttgaatc aacgatcgat aataaggacg cttcaatttt tgtttgtctg gtcgccaagt
    78721 taacgggtaa ttgtcataag aattaatagg cattttctcc actccttaaa attgtatacc
    78781 atacaatttt accattgatt gtattgattt tagaagttaa tcttttgtga ggagggaatt
    78841 gtctatgaaa attattaatt ttgaggaagt agtagcttct tttagttttg aagaagcgat
    78901 tcaagtaatg aaaaaatgtt tttttgatta tgaaagtggt aaaatcagcc aaaatcctcg
    78961 attggtggaa attttacctg acggaaaagg caaaaatatg tttgcgatga tgcctgctta
    79021 tttgggggag aacagatatt ttggcacaaa agtcattacc gcttttccgg ataatcatca
    79081 gtatcattta ccttctcatt taggagagat tttcttgttt gatgctcaaa acggactacc
    79141 caaagcattg ataaacgcaa atgcagtcac ctggattcga acagctgctg tatctgcgct
    79201 ggcaacagat tacttagcaa atccgcatgc agaaacactt gctttaattg gagctggtca
    79261 acaagcattg tcgcatttga ctgcgatttc taccattcgt cccatcacta cagtgtttgt
    79321 ttacgatatt ttagaagaaa gacgaaatac ttttatcgct aaagctaaaa aacagtatcc
    79381 taaaataacg tttataaatg caatatcagt agaagatgca gtacgtccag cggaaatcat
    79441 ttgtacgttg acctctagta aagaggcatt tcttcaaaaa gagtgggtaa gggaagacgc
    79501 acatatcaat gctgtgggca catttactcc tgatacaaga gagataagta catcgttgat
    79561 ggaaacttct caaatctatg tagatgatta ctcagctgcc ttaacagaaa gcggggacct
    79621 gcttatagcc atggcagaag gagatttaga ggaatcttgt attgttggta cattaggcga
    79681 attagtttct gagaaaaaaa cattttataa aggagaatcg aggccgacga ttttcgacgc
    79741 agttggtcta gctattgaag atctttgttg tgcagaatat atttataaca aattagagaa
    79801 aggggcttta aaatgaactt agattattac gtagttgatg catttgcaga tgaggtgttc
    79861 aaaggaaatc cagcagcggt ttatgtgcta gaagaatggc tgccagaagg tacgatgcaa
    79921 aaaattgcca ttgaaaacaa tttatctgaa acagcattta cagtgaagaa aaaccaagaa
    79981 tttgagctta gatggtttac gccagatcga gaaatcgatc tttgtggtca cgcgacatta
    80041 gcaacagcat ttgttttatt taactattac aaaatacctg atgaaacgat taaattttct
    80101 actcaaagcg gtaatctatt tgtgacaaga attaaagatt attattacat ggattttcct
    80161 agtattatgc cgaaaaaagt gccgatattg tctgaatatg aagaagcgat tggggctaag
    80221 attaaagaag cctacttagc acgtgattta tttttcgtat tagaagatga aaaaacggtg
    80281 gctaaattgc agccagattt tacagctatc aaaaattttg aattaggaat aggagtcatc
    80341 gtgacagcag aaagtgtgca aaaagacttt gtttctagaa ccttctttcc aaaattaaca
    80401 atcaatgaag atccagtatg tggatcagca cattctaatc ttattcctta ttgggcagaa
    80461 agaatgaata aaacaaaatt gtcagcttat caaatgtcat caaggggcgg ggatctagaa
    80521 tgtgaattaa aagaagatcg tgtgataata ggaggaaaag cagttttgtt ttctaaaggt
    80581 acctcgttta tttgatttct ttcaaatgaa ttaaaaataa attggtggag agtggcaacc
    80641 ttatagctac aatggttgtt aaaaaaagac gcaaactttt tcaatttaat gaaaagtttg
    80701 cgtctcattt taattattgg tgtttgtttt ttattcaatc aagagtaaaa tgccccatac
    80761 taactatcct cggatgactt cgattttata accatcaggg tcaatgacaa agtagtaaga
    80821 aggcgcagtg ccaggtaatc cttttaagtc agtaatctca agaccggcag ctttatgttg
    80881 ctcgtgtaat ttttctagat catcagctgc tatagcgata tgaccatagc cgtctcctag
    80941 atcatacgca ccatgatcat agttgtaagt caactctaat tcatagtcat ccccaggaag
    81001 tgtcaaataa acaagtgtaa atttgttttc tggaaaatca cggcggcggc tttcttcaaa
    81061 accaaatgcc ttttgataaa attcgattga tgcttcaaga tctttcactc gaacacatgt
    81121 gtgagccatt ttcatagatt catctctcct tttcctttta ctcaatcata acaaaaagaa
    81181 gtaaggaaat agttgatttg tgcttgttca tgagaaattt ctcatgtaaa atggatagaa
    81241 aataaaactg ttaaggtgga aactattcat ggataaacca atttttggtg aaaaaaagca
    81301 atttgctgat tatcaaaccc gttatgcagc atatattgtc atagaaagag atcagcagat
    81361 tgcagtaatc gaggctccaa atggtgcttt ttttcttcct ggcggggaaa ttgaaggaga
    81421 agagacgaaa gaagaagcga ttgtccgtga gctgatagaa gaaatgggaa ttgtggcaga
    81481 aatttcttct tatctgggag aagctgatga gtatttttac tcgaattatc gtgcaactta
    81541 ttattataat ccaggatatt tctttgttgc tgattcttgg aagcgtatag gagaaccaac
    81601 tgaaaagacc aataaaattt ggtgggtgag ccctcaagaa gcgcttgtga aattgaaacg
    81661 tggtagccac cgatgggcag tcgagagatg gatcgaaaaa aataaaaact gaaagaaagc
    81721 gagtagatca gctttctctc agttttttta tttattacag tacatatttt ttgattgctt
    81781 cagctacacc gtgctcgtcg tttgatgaag tgatgacatt tgctgcttct ttgacaagag
    81841 aaacggcatt tcccattgct actcctagac cagcatattc aatcatggat aagtcgttct
    81901 cgttatctcc gatagccatg atttcatctt gatcaatacc aaggtgctgt gcgagattcg
    81961 caactgccgc acctttactt gcttctttat ttagtacttc gaagtaatag ggcgcacttt
    82021 tgaccgttgt gtatttatca cggaaagttt gcggtaaacg cgcaattgct gcatctaaaa
    82081 tttctggttc gtcgatcatc atcattttga cgatgttcat gtctggtgtc atttcttcag
    82141 gtgttcgata ttttagcggc atcttgacta aacttgcttc gtggatcgta taagcgctga
    82201 tatctcgatt aggcgtgtag atcgctttgt catcgatcga atggagatga ctgccgacac
    82261 ggcgtgccat cacttcgatc tctaggaaat cttcatgtgt cagtccgtga cgggcgatga
    82321 ttttacctga tttcgtttgt tgtacgagtg ccccgttata agtaataacg taatcattat
    82381 cttgaaaaag gttcaactcg tttaactgtt cctggacacc tggtaaggga cggccagtgc
    82441 ataaaacgat cgaaacacct tttgcaacag cagcggcaat cgcttctttt acttcttttg
    82501 ttacttctct tttctcattt aataaagtac catcgatgtc gatagcgact agtttgatag
    82561 acataatttc ctccaatata ttttaattta tttcaatcaa tgcgccatta cggatatggc
    82621 tggcaaattc ttgataagtt tcgtcaaata aatcataatg atcacgcaag gacggatcaa
    82681 ccatttcttt tggaaagaaa aatcgctcat ctccttgttc ttgtcccgct aatgcagcaa
    82741 caagctgact aacctgtgat aattctatca aagttccgtc atttcgcaaa atctcgattt
    82801 gtgtgcgatg tctgccttgt tctgggcgat aaaaatcata aggtagatcg tagctagaat
    82861 tcacagcagt gtaataaaca ggattatatc cgaccttttc tactaacaaa gtgagttctt
    82921 ggactaattt tgaatcccgg ttgccagaaa aagtagcaga tttcagtggt ttacgattca
    82981 aaaaacgttt agctaaatca tttaaaatag gatcagcaga ttcagaccat tgagtaaagt
    83041 aagtgcccaa gaccccatca tcaagtttga ggtattcttc taaagtaaag cttccgtcaa
    83101 gaaatggcag aagtaattga gaatggagtt caaaactgct ggcatcttct tgatacaact
    83161 cgtgtgcgcg atgaagcaga tgctccaaaa ttacttccat accacgggaa acaggatgga
    83221 agtacacttg cacatacatt tgatatcggc taacgatata atcttccact gcatgcatgc
    83281 cactcatgga aaaagcgatc ccgccttcat aaggacgaat cacacgtaat attcgggtaa
    83341 gatcaaatgt tccatattct gttccagtga aataagcatc ccgaagcaaa tagtccattc
    83401 gatctgcatc gatctgacta gaaatcattt ggacaacttg tgggttgggg taagtttttt
    83461 ggatcacact agctaccttt tcaggaaaac cttcttctac tcggttaaga atctgataca
    83521 cttctgtttc tggagaagtg atgatctcta cagtgatggc ttcatgattc gtatggaaga
    83581 tatgttcaaa tgtatgagag taaggaccat gaccgacatc atgcaacagt gccgcacata
    83641 aagtcaccag ccgttcctga tcatcccagc ctccgttgcc tattttttct tttgaaaaat
    83701 ttcgagaaaa gatatcgcag attcgtcttg aaatctcata aacgcctaat gaatgagtaa
    83761 aacggctatg ttctgctccg tgaaaagtga aagaagaagt gcctaattgt ttaatgcgtc
    83821 gtagacgttg gacttctttc gaattgatca aatctaagat tacttgatgc tggacatgga
    83881 tatagttatg gactggatca cgaaaaactt tttccatagg cagcatttga tatttataag
    83941 gggttgtcat aatgtagctc ctttatgtta ttacgttgtt ccattctctg gatttggttg
    84001 ttccattgct ccagctggat ttcttttttt agccagtcgg tagaatcctg taaatcactt
    84061 gcagaataca gcttttcaaa agcttttgca aatgcttctt tgacttcttt tacaaaaagg
    84121 ggttggtcaa gcagttcttc aagtgttgcc attgtagcag gatccactgc aggatagcca
    84181 tttgtaccaa agtcttcttt taaagcagat tgataaaatc gcttcatgac ttgcccgcgt
    84241 ttttcctgat taccgttgac acttaagtac atcataacag aaatcccatt tttgatccga
    84301 cgctgagcga taccggcaaa ttttttgcca tggatgctta aatcataagt tccaggacaa
    84361 taagaatggg tgatttcgaa tgcttgtatc ggtgcctttg gaaaagcgta tttagtcaat
    84421 aggagcattt gctcgtaagc gtcatctatg gttatttttt ttgtgtcact ttgggggaaa
    84481 atcaaagaaa tattcaaaat tccttcatct gatacgatcc ctaatccacc tgaatttctg
    84541 atcactggag cgtaacctgc atctttcagt gtttggatcc cgtcacttag aaaaggagtt
    84601 cgaacatcct tcatacctaa gatgactgtg cagtcatatt gccagaaatg taaaaagatt
    84661 tgctggtgtt ctttagaata ttccgttaat atatctgtta atgcaaaagg ggaaaagtcg
    84721 tttttttgat aaatgtgctg atctagtcga atcgcagggt tcattcaacc ggctcctttg
    84781 tataaattca tattttctac aatattatac tctaaaatca aagagttgtt ttggaaaaaa
    84841 ggttttctgt aaaaatggac aagttggttg acaaaacaaa agaaactagg aacaatgtag
    84901 ctatgagaag taaaggagaa tgaataatgg aattatcaca aggaacaccg atttcaatca
    84961 aattgcgtac aaaagtaaaa cagcaagggg aagtgcaaga tttttatttt gatttgaaag
    85021 ggcaaatggt gacaattggc gatacgctgt acatacgtta taaagagatt caggaggaga
    85081 cgggcgatga gattcctgta acgatcaaat tagttccaga tggtcatgta cagctgatcc
    85141 gtgcaggaga aatgcggatg cgtttgaaat ttggctataa agaacggtta gaaacatcct
    85201 atcgaacacc atacggtatg atccagattg ctacttttac gaaagaactg catgttagtt
    85261 tgaaagaccg tcccacagga gggaaggttc gaatcgatta tgatctgttc atgggaccgg
    85321 aaaaaatcgg cgaatattat ttgaccttgg attttacagc gtaaatataa aagaaaagtt
    85381 tgattttttg tgtctgattt tgtatgataa ggagtagact gtgaaaggac gtgtcctgat
    85441 tggaaattag tgtatttgaa ggtgcaaaca aaagcgaatt atcaatgatc gaagtagcac
    85501 acgcgatctt agaacaacgt ggcgatgtca tggatttttc tgatttagct aaccagatcc
    85561 aaaactatct tgggaaatca gacagtgaaa ttcgtgattc actcgcacaa ttttatactg
    85621 acttgaatat tgacggcagc tttatctcat taggggataa tcgttggggc ttgcgttcat
    85681 ggtatgctat cgattcgatc gatgaagaag taaaccatgg aatggacgaa gaggatgaag
    85741 atactccacg tcgccgtaaa cgcaagaaag tcaacgcctt tatcaatgat gatgaagacg
    85801 cgatcgatta caatgacgat gacccagaag atacagatct gacagaagaa gatgacgatg
    85861 atctgtttga tgacgatgat gatgaagatg aagaaatcgc tgcttataat tctgacttgc
    85921 aagaaatcgg agcagatgac ccgacagatg atgaagaaga cttgccagga aatatcgaag
    85981 aagatttaag tatcatagac gaagacgatg atgatgaaga ttatgaagag gaagaatttt
    86041 ctgactctga aaaagaataa acattatttt cttacgagag gttgtgacag agacgatcag
    86101 cctatcagaa taaggaggtg tgacacgatt tttgtcacac cttctttttt gtatataaaa
    86161 atcccaagta aatacataaa aaataaaaaa attgaaactt ttagcgcacc ttgtacgtca
    86221 tattaagtga ggcagaaagg agtggagaat gatttttact ggatataaga aaaaacggca
    86281 gatcgaaaaa taccgtcacc tgctgaatgg actcatcgaa actgattatc aaaaaatgtt
    86341 ccgtatcacg atgaattacg tacatgataa agaagaggcc ttagatgtga tgcaagatag
    86401 ttttcataaa gccctgaact attttgaaaa agaaaaagag atcgagcatt ttagtgcatg
    86461 gttttatcgg atattgatcc gcacggcatt agatagttgg cgcagacaaa aaaggacgcc
    86521 tgtggactta tttgaaattc aagatatccc ccaacagtta cctttagaaa cttccgttgc
    86581 agagctccat atgattttag ataaaataga cagtccggaa aaagagattc tgatcctcta
    86641 cttttttgaa ggatttcgtt tgaaagaaat tgcgactatc ttggatatga atgaaaacac
    86701 agttaaaacg aaaatgtacc gctcattgaa tgctttacgt caaatcctag aatgaaggag
    86761 agaagagtgc catgtattcc caaaaagaaa atttaaaaaa actaaagaaa acttataaag
    86821 aacaagcaat tcccaaaggg cttaaagagg agatccgcca gcgttttatt atcgaagagc
    86881 aatcatttat aaaagcaaag cggagaaaga gacgtctcca agggttcgga gtatctttgg
    86941 ctatcgtaat gattacaaca agtagccttc tttttaatag tcaagttcga agctttgcag
    87001 aagatttacc catcttagga tcagtcattg aattgatctt aggcgaacgc tttactgatc
    87061 gatctgaaaa aatcgatatt caggtaccga agatcaatac acaaaatgag aaagaaaata
    87121 aaacaattca tggattaaat caaaaatact ttcgcgaagg acaagcagat tttgaaaaag
    87181 ctgaaaaaga atatggaaat tttgaaacgg atcattacca agttttggga gattatcaga
    87241 aaatcgtaga cgataaccgg tttctcgtga ttgaaaggca gatcacccaa acagcagcag
    87301 atagccatgt tgaaaaaaga tacgacacaa tcgacaagaa aaacagtgtc cagctctcac
    87361 ttccactttt attcaaagat gacacctatc tatctgtttt gacaaaagaa gtcaaacggc
    87421 agatggccga acaagtcaag gaagatccat ctaagtacta ttggactgag caagatattc
    87481 aagaagggac gatagaaaaa ccaacacttg ttacgcctac acgaagtttt tatttgaaca
    87541 aagagcatca attagttttg actttttctc aatacgaaat tgctcctggt tatatgggta
    87601 caccagaatt tgtcattcct aagtccgtga caaaaacgat tttggcatcg gaagattatt
    87661 tggatcatta gacgagaagt agttgcgact agcagtttca attttcaagt aagtacaagt
    87721 aaataataag aagagaaaaa gagaaagaag agatatagtg aaaagaaatt atttagttat
    87781 cagtattatt gctttatccg tgcttttgtt tttcgaaatt acttcggtgg cctccttgat
    87841 caccgaagta aaaggacaaa cacactcttc ggagcattcg tcacaatctt tcaaacaatc
    87901 agaacaatca accattaaaa gccaatcaac tgaaacagct aacgtcaaag aagccattca
    87961 agaatcagcg gaaaaggtac aaagtcagtc atcacaatca acacaagaca gtacaaaaac
    88021 gagccgagat ccggctgtca aaagcgtcgc aatcagcttt gatgatggac caggagcgac
    88081 cacaacaccg cagcttctgc gaatcttaaa agaaaaaaac gtgcatgcca cttttttcgt
    88141 cttaggagaa aatacggcgc agcatcctga aatcgtgaag cagacagctg aagcagggca
    88201 cgagattggc aattacacat acgatcatca gaatctggcc actctttctg cccagtcgat
    88261 gacggaggaa gtgacgaaag cagacactga gatcaaaaaa gtcactggca aaacccccac
    88321 ttttgttcgt ccgccctatg gttctgtcac gaatgtagga gcaacgatca tccagcgacc
    88381 gatcatcgaa tggtctgttg attcagaaga ttggaagaca agaaatcctg atttgatttt
    88441 gcagaagatc caagcaacag tatacgatgg ggcaattatt ttattccatg atatctatcc
    88501 tgaaacgatt cgtgccgttc ctcaagtgat cgattatctg aaagagcaag ggtatcgcat
    88561 cacgacagtt ggggatttat tagggcatcc aacggctgtc gagaactatt atggcagaaa
    88621 cgatcatcgg ccagttcagt aagtgagaca agtatcttta ataaataaca cattttaata
    88681 agtagttgaa cacataacta ccttacttgc aaaggcttaa caatatctat acaggtacaa
    88741 caaaaaactg tccaccaatt ttctttggcg gacagttttc acttaaaaat aaagaagcaa
    88801 ctattcgtaa attatgctaa aatagcagta gaacgcgtcc tgagggaatc gaacccccgt
    88861 ctcaagaacc ggaatcttac gtgatatcca ctacactaag gacgcaagca ctgggataat
    88921 tgtaactaaa cagataaaaa attacaaggg gattggacaa aaaaatgaaa tttgagcaaa
    88981 atttttcaca aaaacagcag cagacacaga aactagccat gacgcaacag ttgcaacagt
    89041 ccatccaagt tttacaatat aacagtgagg agctgttggc attcgttgag aatcaagcaa
    89101 tggaaaatcc attggtggaa gttgttgagc cggaatggca gccagattac ataaaagctt
    89161 cttcatcttc ttatgaagga gaagagacaa attacctaaa tcagattcct gatacaaaag
    89221 ggtctttatt tgattcattg atcgaacaag tccatttgaa ttaccgagat acttttttga
    89281 ggaaaatcgt tctttatctt gtagaataca tcgatttgaa cggatttttg acgattagtt
    89341 tagaagaagc cggaaaagag attggagcta cgcctatcca aatgctcgat gcgttgactc
    89401 tgattcagca attagaacca gctggagtag gtgcacgtag tttgcaagaa tgtctcatgc
    89461 ttcaaacaga acgagatgat tatgcgccgg aattagctta tatcgtgttg gaagaatgtt
    89521 ttgaggaact ggtggagcga aaatggaaag aaatcgcaca acgtttttct gttgatctac
    89581 atgctgttca gcagatattc gactatttac aaacgttgag tccaagccct ggccggattt
    89641 tcgaccgtag cagcgaattg tacattattc ctgatgtccg ggtattagtg gacgacgata
    89701 aaaatgtaca agttatctca aaccgaaaaa atcagccaaa tatacgcttt caagagagtt
    89761 acttcaaaca aatgtcacaa caagcagata aagaaactga aaattattta aaagaacgga
    89821 aacaggaatt cgaatggttg aagaaaacga tcctacaacg tggggataca attttgcggg
    89881 ttgctcaagt cattgtttcc cggcaaaaag ctttctttat cgacaaggaa cgtccaatca
    89941 agcctcttac gttaaaggaa gttgcaactg agatagatgt gcatgaatcc acggtcagtc
    90001 gtgcagtcaa cgggaaatat ttggaaacag atttcggtgt atttgaatta aaaaaatttt
    90061 tcactacacg aattcctacg aatagtacag aacagacaga agacctttca gcagatacag
    90121 cgaagaaaaa gctgcaggaa ttagtcgatc aagaagacaa aaacaagccg ttgtcggacc
    90181 agaaattggt tgaattgctg aaaaaagatg agatagcgat ctcaagacga acagtagcaa
    90241 aatatcgtga tttattagga atcccgagtt catcaaaaag aaaacgttat gataactaat
    90301 cagtcaaaag actagaaaaa gtatttcact ttttctagtc tttttagttg aaaaacgaga
    90361 gcgaaactgt tagacttaca gtcgtgaggt tgagatttcc ctttattgat gtgaaattcg
    90421 aatagttaat ttcttttttt atcgtatatg ggtcgtttta agtctacatt ggacgtaaag
    90481 tgtccaacta aggagatcgc tatgctggat gaaataaaaa tgattgaatc tgttgcacca
    90541 gatattatcg aagtgttgca agaacgctat aaaattttac gaaatatcta ttggatgcag
    90601 ccgattgggc gtcgaagttt atcggaaagt atggggatca cagaacgagt cttacgaaca
    90661 gaaacagacc ttttgaaaaa tctgaatttg atcgacacct caaaaagcgg tatgacgctg
    90721 acaactaagg gcgaagaagt ttatcaaagc cttgaaaact tcatggatca gcttttaggt
    90781 acgcatcaaa ccgaacaaca gttggcagaa tattttggta accaacgctg tatcgttgtt
    90841 tcaggaaaca gcgaagagca gaccaaagtg gctgatgcat tcggcgaagc gctgagcgaa
    90901 gccttagacc gactacttcc agaaggcgag aatatcatcg ctgtgatggg aggaactact
    90961 atggctgtgg tagccgaaca attgtctaat ctggaaaata agaaacggca taacctgttt
    91021 gtccctgcaa gaggcgggat tggtgaagcg ataactgtac aggcaaattc tgtcagtgca
    91081 agaatggctg ctaaagcaaa cggtaaccac cgcgcacttt atgttccgga acaattaagt
    91141 ctggcaactt acaattcttt actcaatgag ccatctatcc aagaagtctt aaacttgatt
    91201 agtgaagcga attgtgttat tcatagtatt gggcgtgcat tacacatggc agcacgtcgt
    91261 aagatgactg aaaaagaatt agtcatgctg aaacaagcaa atgctgttgc ggaatctttt
    91321 ggctactttt tcaatgaaaa aggtgaagtc gtttataagg tccctagaat cggcatagaa
    91381 ttgcaagatt tggaaaaagt cccgatcatc atggcaatcg cgggcggaaa atcaaaagct
    91441 aaagcaattc gagcttatat gaaaaatgca ccaaaacaaa cgtggctcat cactgatgaa
    91501 gctgctgcaa atgagatttt aaaaggggta accctttaaa ataaatattt ttttgatttt
    91561 cataaggagg aaatcttaaa tgacagttaa agtaggtatt aatggttttg gacgtattgg
    91621 acgtctagca ttccgtcgta tccaagatgt agatggaatc gaagtagtag caatcaacga
    91681 cttgacagat gctaaaatgt tggcacactt gttaaaatac gacacaactc aaggacgttt
    91741 caacggaaca gttgaagttc atgaaggttc attcaacgta aacggaaaag aagttaaagt
    91801 attagctaac cgcaacccag aagaattacc atggggcgaa ctaggcgtag atatcgttct
    91861 agaatgtact ggtttcttca cttctaaatc agcagctgaa aaacatttaa cagctggtgc
    91921 taaacgcgtt gttatctctg ctcctggcgg aaacgatgtt ccaacaatcg tttataacac
    91981 aaaccacgaa acattaactg gtaaagaaac agttatctca ggtgcttcat gtactactaa
    92041 ctgtttagct cctatggcta aaacattgaa cgacaaattt ggtgttgttg aaggattaat
    92101 gacaactatc cacgcttaca caggtgacca aatgactcta gacggacctc atcctaaagg
    92161 tgacttccgc cgtgcacgcg ctgctgctgc aaacatcgtt cctaactcaa caggtgctgc
    92221 taaagctatc ggtttagtaa ttcccgaatt gaacggtaaa ttagacggag ctgctcaacg
    92281 tgttcctgta ccaacaggtt cattaacaga attagtaaca gttcttgaaa aagaagtaac
    92341 tgttgacgaa atcaatgcag caatgaaaga agcttcaaac gaatcttacg gatacaacac
    92401 agacgaaatc gtttcttcag atatcgttgg tatgacttac ggttcattat ttgatgctac
    92461 acaaactaaa gtaatgacag ttggcgacaa acaattagtt aaaactgttg cttggtacga
    92521 caacgaaatg tcatacactg cacaattagt acgtacttta gaatacttcg ctaacttata
    92581 agatagacaa acgtacaagt gtaaattata gacatgtaca tttaaaagcg gggaagcaat
    92641 cgcgcttctt ccgctttttt tgataataag tttattcagg aggaaataaa atggctaaga
    92701 aaacagtgaa agatatcgat ttaaaagaca aaaaagttct tgtccgtgtt gacttcaacg
    92761 ttcctttgaa agacggcgtg atcactgacg acactcgtat caaagcagca ttgccaacaa
    92821 tcaactacgt tctagaacaa ggcggaaaag caatcctttt ctctcacctt ggacgtgtaa
    92881 aaacagaaga agataaagaa ggaaaatctt tagctccagt tgcaaaacgt ctaggcgaat
    92941 tattaggtaa agaagtaaca ttcgtacctg aaactcgcgg agaacaatta gaagaagcaa
    93001 tccgcaacat gaatgacggc gacgttgtcg tattcgaaaa tacacgattt gaagatattg
    93061 acggtaaaaa agaaagcaaa aatgatacag aactaggtaa atactgggct tcattaggcg
    93121 atgtatttgt taacgatgct ttcggtacag ctcaccgtgc acatgcttct aacgtaggta
    93181 tcgcttcaac tggtatccca acagttgctg gattcttgat ggaaaaagaa atcaagttca
    93241 tcggtgaagc agtagaagaa ccaaaacgac caatgattgc aatccttggt ggcgcaaaag
    93301 tttctgataa aatcggcgta atcgaaaact tgattcctaa agcagataaa atcttgatcg
    93361 gtggcggaat gacttacaca ttctacgaag caaaaggaat caagatcggt aactctctag
    93421 tagaagctga taaagtggaa ctagcaaaag aattaatcga aaaagcaggc gacaaacttg
    93481 tcttgccaat cgacaatgtc tgtgcaccag aattttcaaa tgatgttgaa acacaagtaa
    93541 tcgaaggaga cattcctgat ggtttgatgg ctttagacat cggcccagca tcagtaaaat
    93601 tatttgctga tacattacaa ggtgcaaaaa cagttgtttg gaacggacct atgggtgtat
    93661 ttgaaatgag taactttgct aaaggtacaa tcggtgtttg tgaagcaatc gctaacttag
    93721 aaggcgcaac aacaatcatc ggtggcggag actcagccgc agcagcagaa caattaggat
    93781 ttgctgacaa attcacacac atctcaacag gtggcggcgc aagcttggaa ttgcttgaag
    93841 gtaaagaatt accaggacta gcagcaatca acgataaata aacgaccaag tttgctcaat
    93901 tctgacgagt aatcgaacaa aaggtgaagg gagttttcat gactccctag ccatttttca
    93961 ataaattaag gagtgtgttc ctcaatgcgt aaacctatta tcgcaggtaa ctggaaaatg
    94021 aacaaaactg catcagaagc aaaagaattt gctgaagcag taaaaaacaa aatcccttca
    94081 aatgacaaag ttgattcagt catcggatct cctgcattat tcttacaaga attaatgaca
    94141 tcagctgaag gtacagaact aaaaatctca gcacaaaact gctactggga aaactcaggt
    94201 gcgttcactg gtgaaacttc accagcagct cttgctgatc taggtgttca ttatgtgatc
    94261 atcggacatt cagaacgtcg tgaatatttc catgaaacag acgaagacat caataaaaaa
    94321 gcgaaagcta tctttgcaaa tggtatgaca ccaatcctat gctgcggcga atctttagaa
    94381 acctatgaag caggcaaaac tgctgaatgg atcgaaggac aaattacagc tggtttagct
    94441 gatctttcag ctgaacaggt gtcaaacatg gttattgctt atgaaccaat ctgggcaatc
    94501 ggtactggta aatcagctga cgcacaaatc gctgacgaaa tttgtggagt tgtacgtcaa
    94561 acagttgaaa aactttatgg aaaagaagta tcagaagcag ttcgtatcca atacggcggt
    94621 tctgtaaaac cagaaaatat tgctgaatac atggcaaaag aaaatgttga cggtgcttta
    94681 gtcggtggcg caagcttgca agcagattca ttcttgtcat tgttagacgc tgtaaaataa
    94741 ttgttgaaaa tttgcgaaaa atgcaagaaa tgtttgcact aatgagcaaa attaactaaa
    94801 atcgtatatg agggaaatcc cttaggaaaa aacaaactca aaggagagac aaaacatgtc
    94861 aattattact gatgtttacg ctcgcgagat cttagactca cgtggtaacc caacaatcga
    94921 agtagaagta tacacagaaa gcggagcttt tggccgcgga atggttcctt caggtgcttc
    94981 aactggtgaa tacgaagcag ttgaattacg tgacggagac aaagctcgtt atggcggtaa
    95041 aggtgtaact aaagctgtcg acaacgtaaa caacatcatt gctgaagcaa tcattggcta
    95101 cgatgttcgt gaccaaatgg ctatcgacaa agctatgatc gctttagacg gaactcctaa
    95161 caaaggtaaa ttaggtgcga acgctatttt aggtgtttct atcgctgttg cacgtgcagc
    95221 tgctgactac ctagaagtac ctttatacca ctacctaggc ggattcaaca caaaagtatt
    95281 gccaacacca atgatgaaca tcatcaacgg cggatcacat gctgataact caatcgactt
    95341 ccaagaattc atgatcatgc ctgttggcgc tccaacattc aaagaagctc tacgtatggg
    95401 tgctgaagta ttccacgcat tagcttcaat cttgaaagct cgcggattag caacttctgt
    95461 tggtgacgaa ggtggatttg ctccaaacct tggttcaaac gaagaaggtt ttgaagtaat
    95521 catcgaagca atcgaaaaag ctggctatgt acctggtaaa gacgttgttc ttgctatgga
    95581 tgctgcttct tcagaattct acgacaaaga aaaaggtgtt tacgtactag ctgactcagg
    95641 cgaaggcgaa aaaacaactg acgaaatgat caaattctac gaagaattag tttctaaata
    95701 tccaatcatc tcaatcgaag atggattaga cgaaaacgac tgggacggat tcaagaaatt
    95761 aactgacgta ttaggcgaca aagttcaatt agttggtgac gacttgttcg taacaaacac
    95821 tcaaaaatta tctgaaggta tcgaaaaagg aattgctaac tcaatcctta tcaaagtgaa
    95881 ccaaatcggt acattaacag aaactttcga agctatcgaa atggctaaag aagctggcta
    95941 cacagcagtt gtatctcacc gttctggtga aacagaagat tcaacaatct ctgatatcgc
    96001 tgttgcaaca aacgctggcc aaatcaaaac tggttctcta tcacgtactg accgtattgc
    96061 taaatacaac caattactac gtatcgaaga ccaacttggt gaagttgcag aatacaaagg
    96121 tttgaaatct ttctacaact taaaaaacaa ataattcttt tctaatgaag atacatgatc
    96181 gactattgaa agatagtcga gtatgatcac ttagttaagt aatcgaactc tctacttgct
    96241 gaaatatcag caggtagaga gtttttttgc aactagcttc tgtatatgat gtttacaaag
    96301 aatggtacaa gaaaagatca tccttgaaaa aggaaagcta acaataacta gcatcatata
    96361 agagctttta aggatagaac agtagaatag gaatctatgg gcaagtcctc tcgtataaat
    96421 aaaataggag ggaagtagca gcatattttt cataaagtgg ctctctttct tcatttttac
    96481 tttggttgct cctatttgaa aattcgagca cactcaaata caataaaaag aaatggcaag
    96541 ggagaggatt agatgaaaaa agaagaaaaa atcgcgattt tacaagagat tatccgaatt
    96601 aaatcagtga atggaaacga aggtgaagta gcagcctatt tgaataagct tttggcaaag
    96661 catgacataa caggagagat tgtttcttac agagatggta gagataattt gattgctcgt
    96721 taccaaaagg gccaatcagg aaaagtgtta ggcctatctg gacatatgga tgtcgtggcg
    96781 gctggtgatg aatcgtcttg gacctatgca ccctttgcag cagaaatcca tgggaaccgt
    96841 ttgtacggac gtggtgctac agatatgaag agtggcttgg cagcaatggt gattgccatg
    96901 atcgaactga aagagtcagg aaaaccattt aacggaacag tcaaattatt agccactgtc
    96961 ggagaagaag tgggtgaact aggtggggaa cagctcacga aagcaggcta tgtagatgac
    97021 ttagatgcct tgatcatcgg agagccaacc aattacagtt tgatgtatac gcacatggga
    97081 tcaatcaact atacagtcac ctcgcacgga aaagaagcgc atagctctat gccagaccaa
    97141 ggttataatg caatcaatca cctaaatgaa ttcattacga aagcaaatgc tgaaatgaat
    97201 cacctcgctg aaacaatcga gaatcctgtc ctaggaaaaa caatccataa tgttacattg
    97261 atcagtggcg ggaatcaagt caacagcatc ccaagccatg cgcagctcca agggaacatt
    97321 cgatcgattc cagaataccc aaatgataaa atcattgcat tgctgcaatc aatcgtcaat
    97381 gaattgaatc aagagacaga ctatcatttg gaattgatga tcgattacaa caaaatacct
    97441 gtcaaagctg atccagattc tcctttgatt cattgcattc agcaacaatt cagccagcca
    97501 ttacctttag ttggagcggc agcaacaacg gatgcagccg aatttacgaa agctaaccat
    97561 tccttcgact ttgtcgtctt tgggcctggt gtcgttactt tgcctcatca agtagatgag
    97621 tatgttgaaa tcgataatta tttggatatg atcgaaaaat atcaaggaat tattttatcc
    97681 tacttagcgt aagatttttt taataaacgc cgtttgtata attaagcgag acaaataaaa
    97741 aagccattta tgttacactc
//
LOCUS       DAKCAA010000003        95023 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000003 DAKCAA010000000
VERSION     DAKCAA010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 95023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 95023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..95023
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.003"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(2..1846)
                     /locus_tag="OUE31_000193"
     CDS             complement(2..1846)
                     /locus_tag="OUE31_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221235.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            2058..2576
                     /locus_tag="OUE31_000194"
     CDS             2058..2576
                     /locus_tag="OUE31_000194"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCU0221236.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            2704..3387
                     /locus_tag="OUE31_000195"
     CDS             2704..3387
                     /locus_tag="OUE31_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HCU0221237.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            3696..3769
                     /locus_tag="OUE31_000196"
     tRNA            3696..3769
                     /locus_tag="OUE31_000196"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3730..3732,aa:Arg,seq:tct)
     gene            3928..4287
                     /locus_tag="OUE31_000197"
     CDS             3928..4287
                     /locus_tag="OUE31_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HCU0221238.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            4410..6041
                     /locus_tag="OUE31_000198"
     CDS             4410..6041
                     /locus_tag="OUE31_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HCU0221239.1"
                     /translation="MFKKYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(6103..6744)
                     /locus_tag="OUE31_000199"
     CDS             complement(6103..6744)
                     /locus_tag="OUE31_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCU0221240.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    6930..7006
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            7026..7334
                     /gene="rplU"
                     /locus_tag="OUE31_000200"
     CDS             7026..7334
                     /gene="rplU"
                     /locus_tag="OUE31_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HCU0221241.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            7361..7705
                     /locus_tag="OUE31_000201"
     CDS             7361..7705
                     /locus_tag="OUE31_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HCU0221242.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            7718..8011
                     /gene="rpmA"
                     /locus_tag="OUE31_000202"
     CDS             7718..8011
                     /gene="rpmA"
                     /locus_tag="OUE31_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HCU0221243.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            8445..11252
                     /locus_tag="OUE31_000203"
     CDS             8445..11252
                     /locus_tag="OUE31_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCU0221244.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            11443..11934
                     /locus_tag="OUE31_000204"
     CDS             11443..11934
                     /locus_tag="OUE31_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0221245.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            12037..13026
                     /gene="manX"
                     /locus_tag="OUE31_000205"
     CDS             12037..13026
                     /gene="manX"
                     /locus_tag="OUE31_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HCU0221246.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            13059..13862
                     /locus_tag="OUE31_000206"
     CDS             13059..13862
                     /locus_tag="OUE31_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HCU0221247.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            13883..14797
                     /locus_tag="OUE31_000207"
     CDS             13883..14797
                     /locus_tag="OUE31_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HCU0221248.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            14880..15254
                     /locus_tag="OUE31_000208"
     CDS             14880..15254
                     /locus_tag="OUE31_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HCU0221249.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            15393..15638
                     /locus_tag="OUE31_000209"
     CDS             15393..15638
                     /locus_tag="OUE31_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCU0221250.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            15810..16874
                     /locus_tag="OUE31_000210"
     CDS             15810..16874
                     /locus_tag="OUE31_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCU0221251.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            17120..17545
                     /locus_tag="OUE31_000211"
     CDS             17120..17545
                     /locus_tag="OUE31_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCU0221252.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            17538..17987
                     /gene="nusB"
                     /locus_tag="OUE31_000212"
     CDS             17538..17987
                     /gene="nusB"
                     /locus_tag="OUE31_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HCU0221253.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            18084..18938
                     /locus_tag="OUE31_000213"
     CDS             18084..18938
                     /locus_tag="OUE31_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HCU0221254.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            18939..20276
                     /locus_tag="OUE31_000214"
     CDS             18939..20276
                     /locus_tag="OUE31_000214"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HCU0221255.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            20281..20505
                     /locus_tag="OUE31_000215"
     CDS             20281..20505
                     /locus_tag="OUE31_000215"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HCU0221256.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            20507..21397
                     /locus_tag="OUE31_000216"
     CDS             20507..21397
                     /locus_tag="OUE31_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCU0221257.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            21406..22224
                     /locus_tag="OUE31_000217"
     CDS             21406..22224
                     /locus_tag="OUE31_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HCU0221258.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            22331..22780
                     /locus_tag="OUE31_000218"
     CDS             22331..22780
                     /locus_tag="OUE31_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCU0221259.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            22798..24480
                     /gene="recN"
                     /locus_tag="OUE31_000219"
     CDS             22798..24480
                     /gene="recN"
                     /locus_tag="OUE31_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HCU0221260.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(24535..24651)
                     /locus_tag="OUE31_000220"
     CDS             complement(24535..24651)
                     /locus_tag="OUE31_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HCU0221261.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(24724..25680)
                     /locus_tag="OUE31_000221"
     CDS             complement(24724..25680)
                     /locus_tag="OUE31_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCU0221262.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            25851..26219
                     /locus_tag="OUE31_000222"
     CDS             25851..26219
                     /locus_tag="OUE31_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HCU0221263.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            26389..26820
                     /gene="mraZ"
                     /locus_tag="OUE31_000223"
     CDS             26389..26820
                     /gene="mraZ"
                     /locus_tag="OUE31_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HCU0221264.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            26841..27800
                     /gene="rsmH"
                     /locus_tag="OUE31_000224"
     CDS             26841..27800
                     /gene="rsmH"
                     /locus_tag="OUE31_000224"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HCU0221265.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            27805..28206
                     /gene="ftsL"
                     /locus_tag="OUE31_000225"
     CDS             27805..28206
                     /gene="ftsL"
                     /locus_tag="OUE31_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HCU0221266.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRRVK"
     gene            28207..30399
                     /locus_tag="OUE31_000226"
     CDS             28207..30399
                     /locus_tag="OUE31_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCU0221267.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            30425..31387
                     /locus_tag="OUE31_000227"
     CDS             30425..31387
                     /locus_tag="OUE31_000227"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HCU0221268.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            31401..32762
                     /locus_tag="OUE31_000228"
     CDS             31401..32762
                     /locus_tag="OUE31_000228"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HCU0221269.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            32788..33876
                     /gene="murG"
                     /locus_tag="OUE31_000229"
     CDS             32788..33876
                     /gene="murG"
                     /locus_tag="OUE31_000229"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HCU0221270.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            33891..35111
                     /locus_tag="OUE31_000230"
     CDS             33891..35111
                     /locus_tag="OUE31_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HCU0221271.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            35267..36592
                     /gene="ftsA"
                     /locus_tag="OUE31_000231"
     CDS             35267..36592
                     /gene="ftsA"
                     /locus_tag="OUE31_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HCU0221272.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            36615..37856
                     /gene="ftsZ"
                     /locus_tag="OUE31_000232"
     CDS             36615..37856
                     /gene="ftsZ"
                     /locus_tag="OUE31_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCU0221273.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            37873..38550
                     /locus_tag="OUE31_000233"
     CDS             37873..38550
                     /locus_tag="OUE31_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HCU0221274.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            38564..39163
                     /locus_tag="OUE31_000234"
     CDS             38564..39163
                     /locus_tag="OUE31_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HCU0221275.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            39178..39465
                     /locus_tag="OUE31_000235"
     CDS             39178..39465
                     /locus_tag="OUE31_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HCU0221276.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            39514..40296
                     /locus_tag="OUE31_000236"
     CDS             39514..40296
                     /locus_tag="OUE31_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HCU0221277.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            40317..41024
                     /locus_tag="OUE31_000237"
     CDS             40317..41024
                     /locus_tag="OUE31_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HCU0221278.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            41286..44084
                     /gene="ileS"
                     /locus_tag="OUE31_000238"
     CDS             41286..44084
                     /gene="ileS"
                     /locus_tag="OUE31_000238"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HCU0221279.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(44133..45659)
                     /locus_tag="OUE31_000239"
     CDS             complement(44133..45659)
                     /locus_tag="OUE31_000239"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HCU0221280.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(45674..46321)
                     /locus_tag="OUE31_000240"
     CDS             complement(45674..46321)
                     /locus_tag="OUE31_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HCU0221281.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(46505..46834)
                     /locus_tag="OUE31_000241"
     CDS             complement(46505..46834)
                     /locus_tag="OUE31_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HCU0221282.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            47011..47739
                     /gene="sfsA"
                     /locus_tag="OUE31_000242"
     CDS             47011..47739
                     /gene="sfsA"
                     /locus_tag="OUE31_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HCU0221283.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            47755..48768
                     /locus_tag="OUE31_000243"
     CDS             47755..48768
                     /locus_tag="OUE31_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCU0221284.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            48768..50045
                     /locus_tag="OUE31_000244"
     CDS             48768..50045
                     /locus_tag="OUE31_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCU0221285.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            50108..52810
                     /locus_tag="OUE31_000245"
     CDS             50108..52810
                     /locus_tag="OUE31_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCU0221286.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            52962..53279
                     /locus_tag="OUE31_000246"
     CDS             52962..53279
                     /locus_tag="OUE31_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0221287.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            53309..53629
                     /locus_tag="OUE31_000247"
     CDS             53309..53629
                     /locus_tag="OUE31_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCU0221288.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            53737..55197
                     /locus_tag="OUE31_000248"
     CDS             53737..55197
                     /locus_tag="OUE31_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCU0221289.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            55265..55486
                     /locus_tag="OUE31_000249"
     CDS             55265..55486
                     /locus_tag="OUE31_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221290.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            55517..55699
                     /locus_tag="OUE31_000250"
     CDS             55517..55699
                     /locus_tag="OUE31_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HCU0221291.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            55699..56112
                     /locus_tag="OUE31_000251"
     CDS             55699..56112
                     /locus_tag="OUE31_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HCU0221292.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            56235..57416
                     /locus_tag="OUE31_000252"
     CDS             56235..57416
                     /locus_tag="OUE31_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0221293.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(57487..57651)
                     /locus_tag="OUE31_000253"
     CDS             complement(57487..57651)
                     /locus_tag="OUE31_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221294.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            57805..57878
                     /locus_tag="OUE31_000254"
     tRNA            57805..57878
                     /locus_tag="OUE31_000254"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:57839..57841,aa:Arg,seq:cct)
     gene            complement(57947..59086)
                     /locus_tag="OUE31_000255"
     CDS             complement(57947..59086)
                     /locus_tag="OUE31_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCU0221295.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(59385..60021)
                     /locus_tag="OUE31_000256"
                     /pseudo
     CDS             complement(59385..60021)
                     /locus_tag="OUE31_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(60134..60769)
                     /locus_tag="OUE31_000257"
     CDS             complement(60134..60769)
                     /locus_tag="OUE31_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HCU0221296.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(60803..61264)
                     /locus_tag="OUE31_000258"
     CDS             complement(60803..61264)
                     /locus_tag="OUE31_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HCU0221297.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(61394..61825)
                     /locus_tag="OUE31_000259"
     CDS             complement(61394..61825)
                     /locus_tag="OUE31_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCU0221298.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDK
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(61843..62163)
                     /locus_tag="OUE31_000260"
     CDS             complement(61843..62163)
                     /locus_tag="OUE31_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0221299.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            62462..63238
                     /locus_tag="OUE31_000261"
     CDS             62462..63238
                     /locus_tag="OUE31_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HCU0221300.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            63253..63456
                     /locus_tag="OUE31_000262"
     CDS             63253..63456
                     /locus_tag="OUE31_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0221301.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            63472..63810
                     /locus_tag="OUE31_000263"
     CDS             63472..63810
                     /locus_tag="OUE31_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HCU0221302.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            63797..63976
                     /locus_tag="OUE31_000264"
     CDS             63797..63976
                     /locus_tag="OUE31_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221303.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(64019..64489)
                     /locus_tag="OUE31_000265"
     CDS             complement(64019..64489)
                     /locus_tag="OUE31_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221304.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            64576..65274
                     /locus_tag="OUE31_000266"
     CDS             64576..65274
                     /locus_tag="OUE31_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HCU0221305.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            65452..65793
                     /locus_tag="OUE31_000267"
     CDS             65452..65793
                     /locus_tag="OUE31_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221306.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            65786..66457
                     /locus_tag="OUE31_000268"
     CDS             65786..66457
                     /locus_tag="OUE31_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HCU0221307.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            66463..67149
                     /locus_tag="OUE31_000269"
     CDS             66463..67149
                     /locus_tag="OUE31_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221308.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            67152..67901
                     /locus_tag="OUE31_000270"
     CDS             67152..67901
                     /locus_tag="OUE31_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0221309.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            67913..68182
                     /locus_tag="OUE31_000271"
     CDS             67913..68182
                     /locus_tag="OUE31_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221310.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            68187..68351
                     /locus_tag="OUE31_000272"
     CDS             68187..68351
                     /locus_tag="OUE31_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221311.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            68344..68646
                     /locus_tag="OUE31_000273"
     CDS             68344..68646
                     /locus_tag="OUE31_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221312.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            68643..68804
                     /locus_tag="OUE31_000274"
     CDS             68643..68804
                     /locus_tag="OUE31_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCU0221313.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            68801..69106
                     /locus_tag="OUE31_000275"
     CDS             68801..69106
                     /locus_tag="OUE31_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221314.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            69106..69462
                     /locus_tag="OUE31_000276"
     CDS             69106..69462
                     /locus_tag="OUE31_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HCU0221315.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            69449..69667
                     /locus_tag="OUE31_000277"
     CDS             69449..69667
                     /locus_tag="OUE31_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221316.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            69664..70083
                     /locus_tag="OUE31_000278"
     CDS             69664..70083
                     /locus_tag="OUE31_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HCU0221317.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            70080..70637
                     /locus_tag="OUE31_000279"
     CDS             70080..70637
                     /locus_tag="OUE31_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HCU0221318.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            70634..70930
                     /locus_tag="OUE31_000280"
     CDS             70634..70930
                     /locus_tag="OUE31_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221319.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            71007..71420
                     /locus_tag="OUE31_000281"
     CDS             71007..71420
                     /locus_tag="OUE31_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HCU0221320.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            71729..71881
                     /locus_tag="OUE31_000282"
     CDS             71729..71881
                     /locus_tag="OUE31_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221321.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(71878..72153)
                     /locus_tag="OUE31_000283"
     CDS             complement(71878..72153)
                     /locus_tag="OUE31_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221322.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            72607..72813
                     /locus_tag="OUE31_000284"
     CDS             72607..72813
                     /locus_tag="OUE31_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221323.1"
                     /translation="MLGQCFGNHARFDSLPATLNAYDGYDYRKKIVKKLYGATYGNVV
                     SVLSVHHQASVTVAEVEDAAVNGE"
     gene            73009..73176
                     /locus_tag="OUE31_000285"
     CDS             73009..73176
                     /locus_tag="OUE31_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HCU0221324.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            73202..73546
                     /locus_tag="OUE31_000286"
     CDS             73202..73546
                     /locus_tag="OUE31_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCU0221325.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            73551..73832
                     /locus_tag="OUE31_000287"
     CDS             73551..73832
                     /locus_tag="OUE31_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221326.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            73935..74249
                     /locus_tag="OUE31_000288"
     CDS             73935..74249
                     /locus_tag="OUE31_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HCU0221327.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            74227..75921
                     /locus_tag="OUE31_000289"
     CDS             74227..75921
                     /locus_tag="OUE31_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCU0221328.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            75941..77119
                     /locus_tag="OUE31_000290"
     CDS             75941..77119
                     /locus_tag="OUE31_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCU0221329.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            77082..77768
                     /locus_tag="OUE31_000291"
     CDS             77082..77768
                     /locus_tag="OUE31_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HCU0221330.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            77768..78928
                     /locus_tag="OUE31_000292"
     CDS             77768..78928
                     /locus_tag="OUE31_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCU0221331.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            78938..79813
                     /locus_tag="OUE31_000293"
     CDS             78938..79813
                     /locus_tag="OUE31_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221332.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            79810..80121
                     /locus_tag="OUE31_000294"
     CDS             79810..80121
                     /locus_tag="OUE31_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221333.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            80111..80464
                     /locus_tag="OUE31_000295"
     CDS             80111..80464
                     /locus_tag="OUE31_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HCU0221334.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            80454..80855
                     /locus_tag="OUE31_000296"
     CDS             80454..80855
                     /locus_tag="OUE31_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221335.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            80848..81252
                     /locus_tag="OUE31_000297"
     CDS             80848..81252
                     /locus_tag="OUE31_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221336.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            81264..81872
                     /locus_tag="OUE31_000298"
     CDS             81264..81872
                     /locus_tag="OUE31_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCU0221337.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            81892..82254
                     /locus_tag="OUE31_000299"
     CDS             81892..82254
                     /locus_tag="OUE31_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221338.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            82456..85887
                     /locus_tag="OUE31_000300"
     CDS             82456..85887
                     /locus_tag="OUE31_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCU0221339.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVKKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            85938..86675
                     /locus_tag="OUE31_000301"
     CDS             85938..86675
                     /locus_tag="OUE31_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCU0221340.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            86685..88976
                     /locus_tag="OUE31_000302"
     CDS             86685..88976
                     /locus_tag="OUE31_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCU0221341.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            89000..91126
                     /locus_tag="OUE31_000303"
     CDS             89000..91126
                     /locus_tag="OUE31_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221342.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            91143..91292
                     /locus_tag="OUE31_000304"
     CDS             91143..91292
                     /locus_tag="OUE31_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221343.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            91289..91735
                     /locus_tag="OUE31_000305"
     CDS             91289..91735
                     /locus_tag="OUE31_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221344.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            91737..91874
                     /locus_tag="OUE31_000306"
     CDS             91737..91874
                     /locus_tag="OUE31_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HCU0221345.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            91912..92205
                     /locus_tag="OUE31_000307"
     CDS             91912..92205
                     /locus_tag="OUE31_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221346.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            92202..92426
                     /locus_tag="OUE31_000308"
     CDS             92202..92426
                     /locus_tag="OUE31_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCU0221347.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            92423..93448
                     /locus_tag="OUE31_000309"
     CDS             92423..93448
                     /locus_tag="OUE31_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCU0221348.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNPYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            93638..93711
                     /locus_tag="OUE31_000310"
     tRNA            93638..93711
                     /locus_tag="OUE31_000310"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:93672..93674,aa:Ile,seq:cat)
     gene            94388..95023
                     /locus_tag="OUE31_000311"
                     /pseudo
     CDS             94388..95023
                     /locus_tag="OUE31_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        32138 a        15515 c        19898 g        27472 t
ORIGIN      
        1 tttatacagg attcgggtaa tttcgagaga gttgaacagt gatccgatca atgaaagtat
       61 ctttttcctg cgttagtgtt cctgtgtaac gatccgctac gtctttcatc atcattaagt
      121 caaaacgttc ctgatcatct aattcttctg tgatgcctcg actaaatagg tttgtatcgt
      181 aatgtgcact atgttcgcaa caaatgacga aatgttcctc ttgttcgtgt atcgacaaat
      241 aaatttttcg atacagtgga ttttcgatgg catgagtttc tctaaaggaa tgctctaaag
      301 cgtggatcaa aagttgagcc agatcgtcat cgttgatagg aagttcttcg ggaagatctg
      361 cttggaaggt tatctgaata ttccgtttgg cagctaactt ctggtaacgc gctaagataa
      421 gatttgtcac ctggtggttg caaaaagaac acagcatttc gaaatttttt gcttcttcta
      481 atatcttttc cacatagttt ttagcttttg tttggtccgt atgcattaaa tcttgcagat
      541 tctccatctc ttggacaaat tccaggcgaa gtgtatttac ttcttggata tgctgtcgaa
      601 gctgctcata atgttgctcc aacaaatcat ttttgatttt taagaaatct acttgtctcc
      661 gatctttgtc ggtatttaag atgtgatcga ttagattgta gctgataata acgattagaa
      721 tgataatata taaaatcgta gaccaattga tcgttgtttg atagatacct aatgccgttt
      781 ggatgtaaat caagcaatgg ataatggcta ccaagacgat ccaaggtgta caagctacat
      841 aaaaacggtt attcttatat gcttcgccaa tgcatgcaag tgaagtgact aaagtgctta
      901 taacactagc aatattagca atcggcatta attcaggaag ttctgcagga gtaaaagttg
      961 cataaagcag aacgccgata aaaatcaaaa gttggaacgt acaaaaaatt ccgtaccatt
     1021 ttttatagta aaacattcgg ctccaatagt agcagatgat gaaagctgac gttaagataa
     1081 taaataaatg agataaaaaa gaatgaacga atggttcaaa aagaatacca cttaaaatat
     1141 cttctgatac agcttcaaat cctaatgcca aagcaaagca acttaagaga ataagtgagt
     1201 attcaagacg tttttgttta tacatcaagt agatcgtata gaaaaaggtc cctatagcga
     1261 taaaaacagc gattatcatc gtcaatactt gcggcactga ttgtgaataa ataaaactaa
     1321 tcaatggtcc agttgttcct agataaactt tcggtggcag tccagcatag ttctgataag
     1381 gagatgagac tgtaagggtc aatttttttc cgatataatt tgctggtaaa tctatcacag
     1441 ccaatgagag tccgggattg ctttcttcct gataatcttt ccgttggtat aaaatctttt
     1501 cgcctagata tacagtaatc cattgatggt ttcctttgat tagtaaattt gcttcgtcca
     1561 acggtttttc aagtgtcgtt tccataatga atgtttcgtc tttatccacg gtaggaatcg
     1621 tacgagtgta cttgctgtca aacttaaaat caggatcatc ttttgtatag aaaacccacg
     1681 aatcttttat ttctttcatt tgattgctgt ccgcaggaga aaaaataaaa taaaagaaat
     1741 aagcaattcc tgttaaaaat aacaatgata atataatgat tatgctccac tttatacgta
     1801 aataaaaaga ttctttttta ttatatatgt tattaaaaaa agacataaag gtattccttt
     1861 ctaaaacttg taatgttagg gtaaacgttt tttaaactaa cgtcaattat ttataataaa
     1921 aaatgagata aagatgagga aatagaatta gaaacatata attattaaag ggaaacattt
     1981 ttacagctat aatttgaaaa aaatttatcg ttattatatg attaagaagg attgaataaa
     2041 gaaagaagtt gaaaacgata cctgattaca aaaaaataac ttttataagt tctataacgt
     2101 tgattatatt tttaattctt attcttctcg tcgtcttggt tccccgaatt tttggtttga
     2161 ctccttatat tattgaggac aaagaaatga gtccatatta tgcacaagga aatctgatat
     2221 atgtacgacc gaaaaataca aatgagattt tagtcggaga tattattaca tattatgaaa
     2281 attcaggaaa aaaaatctcg acgcgtcgcg taatagccgt tgaaaacaac cacgaagatt
     2341 tttatacaaa agctgataca aagacttata ttgagcctgg agtagtaaaa aagagaaata
     2401 ttatcggtag tcccatcttt cagattccat atattggact agtcctttca aaaacggcat
     2461 ttgcatggat tcaggggtta ttctttacga ttgctttttg cctaacagga atcacagcat
     2521 ggaatacctt tgtagagttg aaaaagaagc ggagacgaac acagaaattt ttgtaagaat
     2581 gttaaaaaca taaatgtatt ccagagatcc aacgactctt ctgaacatga aacacgagaa
     2641 aacactcatg cagcttgtag atttagtcag ttgttcgtat aatgtgtgaa gaggaggagt
     2701 agtatgcgca atgaaatgat gcatcgtcct gtagtcaaag aagaactatt ggattttatg
     2761 cgtacccagc aaaaaaaatt accgggtgag ctaggcaaac tggaagaaga agctcatgta
     2821 gcagaagtac cagttattcc ccatgaaaca gttgtatttt tgaaattttt acttggacag
     2881 cttcagcctg aacgaatctt ggagatcgga gcagctatcg gtttttcatc aagtgtcatg
     2941 gccacgacaa tcggagaaaa cgctcatgtt acgacaattg atcgtttcga tgtcatgatc
     3001 gagaaagcta aaaaaaacta tgaacgtcta ggactgacag ataaagtgac tttgcttgaa
     3061 ggtcaagcag cagatatctt gccggagttg tctggtccgt atgactttat ttttatggat
     3121 agtgcaaaat caaaatatat tgaattttta cctgaatgct tacgtttgtt aagaaaaggt
     3181 ggcgttttga tggtagatga catcttccaa ggaggaacga tcttgctccc agatgaagag
     3241 attccccgtg gcaaacgagc tatccatcgt aaattaaatg aatttcttcg tgttgtgatg
     3301 gatcatcccg atttgacatc gacaatcttg ccattaggtg atggtgtgat cttaatgaca
     3361 aaggaatcag aaacaatcga gttgtgatac atgattatgg cagcctgtag ataatcgatt
     3421 gaatcgaggg ctcaattcga acttgatgta aaagtttcta tatttgtaag tcaattaaag
     3481 gatacaggaa atctaaataa acaggagtag catgaagtca atgtagctcc tgttttcaat
     3541 tgataacctt agaacagctg aaggagaatg tctcgtttta aaagattgat ttagtagttg
     3601 ggccaaaata attcattatt tgctaattaa ataactattt cgtattgaca gaagcaattt
     3661 aattatctat aattattgat gttccgctga ttcttgtcat agtagctcag ctggatagag
     3721 catccgcctt ctaagcggac ggtcgggggt tcgaatccct cctgtgacgc taaaaaaccg
     3781 ttagaaactg aggtttctaa cggtttttct ttgttttttg tgccaatatt gtttgttttc
     3841 aaaggcaaat aaaataaaaa aacatcctta tcgagtacaa ttataaggag caaaaaaata
     3901 aaactcatca gaaaagagga agaagatatg acgatactat ctagaatttt agtgactcta
     3961 gttgcaattg aattttttta tatcatgtat atcgaaacgg tgagaactga ttctgacacg
     4021 acaagtaggg tttttaaaat gagtaaagaa gagttaagca gaaaatctgt tcaaacattg
     4081 tttaagaacc aaggagtgta caatggacta ttaggagtgg gactacttta tggagcttat
     4141 ctttcttccg catctaaaga aatcacaagt atgctattaa tatctatttt ttttgttgca
     4201 ttatatggca gtttgactag cgatcgttgg attttactca aacaaggtgg gctagctctg
     4261 ttggcattgc tttctatttt cttataaata tagaaaaaat aagaatttat ctaacaggaa
     4321 actttgtgaa aaatattact ttatctcatg aaatatgata ttctaatgaa tggtatttta
     4381 gaaaatttca tgaaaaagga gttagatagg tgttcaaaaa atatgtttcc tcactaaaaa
     4441 aagaattttc aggttatgat ctttcaagat ttcagaaaga tcttttggct gggatcacag
     4501 tagctgctgt agcattgcct ttagccttgg cttttggggt atcaagcgga gctgatgcgg
     4561 ccgcaggttt gattacggct atcattgccg gtatcgttat tggcggttta tcaggcggtt
     4621 tttatcaaat atcaggtccg acaggtgcga tggcagctat cttgatgtct attgcggcaa
     4681 caaagggaat gcaaggtgta ttgcttgcta cttttttagc gggtctattt ttacttgcag
     4741 caggactttt ccgattagga acactgactt cttttatccc agcacccgta attacggggt
     4801 ttacttcagg tattgctatc attattgcat taggtcagat cgataattta tttggtgttc
     4861 actcggaagg tacaaacgtt attgaaaaac taagtagtta tcaaacgata ggatttccga
     4921 taaacacagc ctctttgatc atgggagggc tagtcatttt agggatgttt atctatccaa
     4981 aaaaatgggc gaaacgaatg cctagttcgc tgctggctat cattttggca acagcagtta
     5041 tgctattgtt ccatttacca gtagcaactg tgggtaagat tccacaaaca ttgatcagta
     5101 gtaatcgttt gaatatggga gattttagct tttctgcctt gcaacaagtg gcagttccag
     5161 ctattagcat tgctttatta ggaatgattg aaagcttgct atgtggtgct tcggctggcc
     5221 gaatggcaaa taagccctta gatagcaatc aagaattaat ggcgcaagga attggaaatc
     5281 tgttgcttcc tttctttggc gggattcctg ctactgcggc catcgcccgt acaagcgtgg
     5341 ccatcaaatc tggtgcacaa actagattag ctggtatgat acatgcagtt gtcttactgc
     5401 tctccatgct tgtttttgcg ccagtgatgt cacagattcc aatgccagca cttgcaggtg
     5461 ttttgattgt gacggcttgg cgtatgaatg aatgggaaac gatcaaggag ctatttacta
     5521 ataaatattg gtcagcagtt ctattgttta tccttacgat gatttgtaca gttatctttg
     5581 atttaagtat tgctatcgtg atcggggtga tcggcggctg tgtatttttt gttgtcaaaa
     5641 gcgctgctat cacgatttca ttagaaacga tcgattggca aagaatgggg ctgccagaaa
     5701 cggaaaagct gaataactgg acagtagtgt atattagtgg tccactgttt tttatgtctt
     5761 cagaaaaact caaaaataaa ttggaagaac taaatcatca cgatggtgtc attttctcca
     5821 tgcgaggcgt accaagtatt gatttgacgg cacgtgcagt ttttgatgaa tttcaagaaa
     5881 aagcagagca aagaggacaa acgattatct atacttcctt gcagccagaa gtagaaaaac
     5941 aactttctca cttgtgggaa catacattca cgcatcaaca tcaaacagtt gctcatgcgt
     6001 tgacagcttt acatgcgaaa tatactgcaa ttagccatta aaacaatgaa aaagaacaga
     6061 caagactgta aactgaagat tttatggtct tgtctgttct ttttaatatt gctgtaaaag
     6121 tgaagctagt acttgccagt cttgatggat aacaggtaca agggagcgat tgtagaaaat
     6181 agctgctgga tgaaaaagtg gaagaattcg atagtttttt tctgaccatt cgtaggcatc
     6241 cttttgttct gttaattgta agacaggccc tgtatagagt tgaccatgat ttttggtaac
     6301 cgtatattct ttgccaagta aacgttgaag accaatgttt ccaagtgtcg caattaattt
     6361 tggctggacc ttcatcagtt cgtaatccaa tattggtgca tgcgcaaata cttcggaacg
     6421 agtaggtgtc cgatttggat aaacagtttc tgactgttgt gtccgtttat tgatccgatg
     6481 agtcacgcga tacgggcggc tccttacagc actggtgata tacacctctt ctcgtgttaa
     6541 gccagttgaa gaaagtgcct gcatcaattc ttttccagct tgaccgctaa aaggaacatg
     6601 cgtatcaatc tctgttttcc ctggggcttc tcccacgagc atcagtttag gatgaagagg
     6661 tccttgccca gcgataaatc cttctacagg acggccgttc attcttaaag aagcttcttg
     6721 tatcagttct tttgggtatt ccatttatgc tcctcctttt tcttttatta taagaataaa
     6781 agaaacacaa tgcgactatt ttatttggta gaactgtgag gatagaaaag cagaagtatt
     6841 gcttgaattt ttgttttact ttttgatttt aaatttagtt gactaacggt tgctgttctg
     6901 gtaagctagt actgttgtaa ttgtggactc cacagctaca accgctcaga acaagtaata
     6961 agcacagcat atgctgtcac ttcggatggc gagtctaagt atatgagaag gaggtgcttt
     7021 atagcatgta cgcaattatt aaaactggtg gtaaacaagt aaaagttgaa gtgggacaag
     7081 caatctatgt tgaaaaactt gacgttgaag caggagaaaa agttgttttt gacgaagtta
     7141 tcttagtagg cggagaatct acaaaagtag gcgctccaac tgttgcaggt gcaactgttg
     7201 aaggtactgt tgaaaaacac ggcaaacaaa agaaagtcgt tactttcaaa tacaaaccta
     7261 aaaaacattc acaccgtaaa caaggtcatc gtcaaccata tacaaaagtg gttatcgacg
     7321 cgatcaacgc ttaatagcgt ttgagaaaga aggcctatat atgatcaaag gaacatttaa
     7381 gcgaaatgac gcaggtcaga tcgtttcatt cactttgacc gggcatgctg atgctggtcc
     7441 ttatggaagt gatatcgttt gtgcgggtgt ttctgcgtta gcgatcagca ctgtcaacgg
     7501 gattgcctca ttagccggtt ttgagccgat tgttgaaatg aatgaagaag aaggcggtta
     7561 tctttatacc gaagtcactt caggaatgac acaagaacaa aacaatattg ctgagattct
     7621 attagaaaat cttttattag gattacaatc gatagaagct gaaaactcag aatatatcca
     7681 aattaaaaca attaatgata aataggaggt gcagaccatg ttgttatcta tgaatctaca
     7741 attatttgcc cacaaaaaag gtggcggttc tacatctaac ggccgtgact cagaatcaaa
     7801 acgtctaggt gctaaacgtg ctgatggaca aacagttaca ggtggatcaa ttctttaccg
     7861 tcaacgcggt acaaaaatct atccaggtgt aaacgtgggt atcggtggag acgacacttt
     7921 atttgcaaaa gttgatggcg tagtacgttt cgaacgtaaa ggccgtaaca aaaaacaagt
     7981 gtctgtttat ccagtagctc aagaagctta attgaatctt atgattaaag aggttgtgac
     8041 aagacttttg tcacagcctt ttttgtttat aaaaataaaa gttgtagtgg aggctacgaa
     8101 gtttactttg tctttttaca cttaatattt ttttgccaat ttggaatcag gatgttttga
     8161 taactatcgt tttcaattga tggaagctat attgtttgct atcagtgaaa taattatatg
     8221 gtaaacagtg ttctttttct tgtttccatt ataaaaatcg tatcgggatt tttcgttctt
     8281 ttaaattgaa catttctatc tatccgcgtg ttatcaacaa aacaaaatca ggtaaatagt
     8341 tgacgaaaca gaaataaata catagtatta tgttttgaag cctaagtaca atagtctata
     8401 gaaaaggagc gataccattg gcaaaacgca ttgaccgaat ttatatgtat gtcaaagaaa
     8461 aaaccgctca tttaacaaag gcagaatatg atcaaggagt aacaacacag gaaattgctg
     8521 aagtgttagg gattcagcga acaaatagca gtaaagatct gaatcagcta gtgcgcgaag
     8581 gaaaactgat aaagacagac ggacgaccag tacgttacat atatcaaaca ctcgttacgc
     8641 acgtaaagcc agttacaaaa catgtagtca gttacaaaga aacgccggtc tctgaagaaa
     8701 aaaatacact ccaaatagat actaaggata tctttgcaaa aatcattgga gctaacggca
     8761 gcatgaaaaa ttcagtggaa caggcaaaag ctgcgatttt gtatccgcca agaggattaa
     8821 attgtttgat tacaggacct accggatcag gaaagactta ttttgcacac gcgatgtatc
     8881 attttgcaaa agcgcatcat gtaatagatg aggaaacgga actgattgtt ttcaattgtg
     8941 ctgattatgc caataaccct gagcttttga tgagtcattt atttgggtac gcaaaaggtg
     9001 cttttacagg cgcagatgaa gaaaaaatgg ggattatcga tcaagcggat ggcggtatgc
     9061 tgtttttgga tgagattcac cggttgccgc ctgaaggtca agaaatgatc ttttacttta
     9121 tggatcatgg aacttacagt cgtcttgggg aaacaacgaa atcccatgaa gcaaatgtac
     9181 ggatcgtagg tgcgaccaca gaagacccag gttcttctct attagaaact tttgttcggc
     9241 gtatcccaat caatatcaaa cttccggctt ttgaaaaacg tcctgcaaat gagaaagtcg
     9301 atttagtaaa aatcatgatt gcccacgaag caaaccgcac gcagcgaaag atttctttga
     9361 cagaagatgt agcaaaagca ttgatcggca gtgtgaccta tggaaatata ggacaattga
     9421 agtcaaatat ccagttagta tgtgcacgag gatttctaaa tcatatgcaa tcacccgaaa
     9481 tctcgatcac aatcgatgat ttgacagaag ggattcgtag cggattgatt caattagcaa
     9541 gcaaccgcag tgcaatggca gagctttcta aaatattgga gccaaagata actgtagcac
     9601 caaatgatac gatcatgaaa atccaatcgg actcctatga gttaccttat aatctatatg
     9661 atatcatcgg agataaagca gctttactga agtcggatgg tttggatcaa gaagcaatca
     9721 atcatttcat ttctacagat atcaacatcc atctgaagtc tttctataaa gaccatggtt
     9781 tttcttttaa tgcagacagc aaattagcag aatttgtaga tccgaaaatc atagaagtga
     9841 ccaatcagat ttatgtaatg gtcaaaagat ctttaccata tgagtttcag caaaacttta
     9901 tttatgctat gagcttgcat atcagttctt ttttgaaaaa aatcaactta ggagaagaac
     9961 ggcatacgaa tgataacatc cgtgagatgg cttttgattt tccagatgaa tatgctgttg
    10021 cgaaagaagt gcgtagttat atcgaaacgt attttcaagt ggagattcca gaaagtgaag
    10081 actattactt gaccgttcta ctcgtctcgt tacgggcaaa tcaagcaagc ggcagaatcg
    10141 gtgtagtcgt tgcagctcac ggaaacagca cagcaagcag tatggtccaa gttgtccaac
    10201 agttgttaga tgcagagaac gtacgagcag tagacatgcc tttggatatg gatccgaaaa
    10261 cagcattgga ccgaattgaa cgcaatgtac aagaagtaga tgaaggaagc ggggtcatac
    10321 tcttagtaga tatggggtcc cttgcgtcgt ttaattcgca aattcaaaga gacactggaa
    10381 ttccagtacg tactgttgat atggtaacaa cttctctagt tttggaaact gtacgaaagg
    10441 tctcagtatt agggacagat ctagatatgt tgcatgaatc attgaaaaat tttcgaggtt
    10501 acgcagaaat atcttctgta gaatctgttc aggaagcaaa acctattcat aagaaaaaag
    10561 ctgttttggc tatctgcgca tctggcgaag gtacagcaca aagaatcaaa gaattgatcg
    10621 aacgagcggt aaacaagcgt caagaaacag aattagaagt tctagctttg tcgattgtgg
    10681 aagtgaaaga agaactgcca gttatccaaa aagaatatca gatcatagct actactggga
    10741 ttactgattt gaatatccaa gccccattta ttcctttaga acgttttatt gatcaaaata
    10801 tcgaagtcat tttggatcag ttgctgatgg aatcagaatt ggaggaaact gaattcatct
    10861 ccctagatga agagtcagct aaaaatacgt gtgttgagtt tatctctgat aacttcatct
    10921 ttattaatgg tagtaagtta atcgatccaa tgtggcaatt ttctacacaa atctctcaga
    10981 cgacgggaat cggcgatgaa gaatatggat tcaaaatcaa cctagtgatg cacacagcag
    11041 gaatgatcga acgtattatt cggaatgaac cattgactgt ggaagaaaac gaattgacaa
    11101 atacaacgaa tgatcctctt tatagccaat tggcagcctc agttgttctg ttggaagatc
    11161 agataaaagt aaaagtgccg atagaagaaa tgtattatct gctacgtcta gtccataatc
    11221 agttagataa aaaagaatac actgtgccat gaatacacaa aaacgataca cttttatagt
    11281 gtatcgtttt tgtgtattgg ttaagaatcc tttaaattca attagtgtat cgtaaaaaag
    11341 ttggcacgct ttttgcttat agtagtgtgt gctaggaggt ggttgttcac acagaaatga
    11401 taggggtttc tgtgaagtag tgaggaagaa ggagttttgc agatggatat tcgattggca
    11461 cgtatagatg atcgtttaat ccacgggcaa gtcgcaacag tttggtcgaa gcaaacaggt
    11521 gttgaacgta tcattgtgat cagcgatgta gtcgctcaag ataaattgag aaagtttcta
    11581 ctaaaagaag ctgcaccgcc ggggatcaca gcaaatgtaa taaccgtgca gaaaatgatt
    11641 caaatctatc atagtggatt attatcacga gcaaaagtga tgcttttatt caccaatccc
    11701 caagatgttg aagcggttgt ccgctgcggt gtacagttga agtcgttgaa tatcggcggt
    11761 atgagtttta ctgaaggcaa atcaatgatt accaattttg tttcagtaaa tcaacaagat
    11821 attgattcct ttcgttactt gaacagtcaa gaagtggagt tagagattcg aaaagtacct
    11881 gctgacagga aaatcctttt gatggaacta ctagcgaaaa tcaaaaaggt gtagcaagaa
    11941 tggttgttgg aaaaggtcaa ataattctgt tgtaatggtt agcaattatt aatatttttg
    12001 aatttgttac aacaaaagta aataggaggt ataaatatgg tagggattat cctagcaagt
    12061 catggacaat ttgctgaagg aatcttacaa tccggttcaa tgatctttgg cgaacaagaa
    12121 aacgtcaaag ccgtgatttt gaaaccaagt gaaggtccag atgacttgag agccaaattg
    12181 gaagaagcgg ttgcttcttt tgataatcaa gacgaagtgt tattcttagt tgatttatgg
    12241 ggcggaacac cgttcaatca atcaaacaca ttattcgaag agcacaaaga taaatgggca
    12301 atcgtcagcg gtttgaattt accaatgttg attgaagcct acgcatcacg cttttcaatg
    12361 gaatctgctc atgaaattgc agcacacatc attgaaacag caaaagacgg tgtaaaagta
    12421 aaaccggaag aattagaacc ggcagaagca ccgaaagcag cagttgaaga cgcacaacct
    12481 aaaggagcac ttccagaagg aactgtggtc ggagacggaa aaatcaaata tgtattagca
    12541 cgtgttgact cacgtctgtt acatggacaa gttgcgacag cttggacaaa agcagtgcaa
    12601 ccaaaccgta ttatcgttgt ttcagatgca gtatcaaagg atgatctgcg taagagacta
    12661 atcgaacaag ctgctcctcc aggtgtaaaa gcaaatgtta ttcctattag caaaatgatc
    12721 gaagtagcaa aagaccctcg ttttggaaat accaaagcat tgcttttatt tgaaaatcct
    12781 gaagacgtat tgacagctgt tgaaggtggc gtagacatca aagaattaaa tgttgggtca
    12841 atggcgcatt cggtcggtaa agtcgttgta agtaaagtat tgtctatggg acaagaagac
    12901 gttgaagcgt ttgagaagct tgaacaaaaa ggtgtgaaat tcgatgtacg taaagtacct
    12961 aatgattcac gcgataacat ggatgatatt ttgaaaaaag caaaagctga attagcaaaa
    13021 gcgtaataaa taatattaaa atttatagga ggcttatcat gtctattatt tcaataattt
    13081 tagtcgtatt agttgccttt ctagctggta tggaaggtat tcttgatgaa tttcaatttc
    13141 atcaaccact agtggcatgt acattgatcg gtttagttac cggtaacctc gaagctggta
    13201 tcgtacttgg cggtacgctt cagatgatcg ctttaggttg ggcaaatatc ggtgccgctg
    13261 tagcaccaga tgctgcatta gcatcagtag catcagcaat tattttagtt ttaggtggac
    13321 aaggtgttaa aggtgttcct tctgcgatcg cgattgccgt tcctttggct gttgcagggt
    13381 tgttcttaac aatgatcgta cgtacaatcg ctgttccaat cgttcatttg atggatgcgg
    13441 ctgctgaaga aggaaacatc cgtaaggttg aaatgtggca catcattgct gtatgtttac
    13501 aaggggttcg tatcgcggtc ccagcagcag cgttgctatt tatcccagca caaactgtgc
    13561 aatcattcct tgaatcaatg ccagcatggt taacagatgg tatggctatc ggtgggggaa
    13621 tggtcgtagc tgtaggttac gctttggtaa tcaacatgat ggctacaaaa gaagtatggc
    13681 cattcttcgt tattggtttc gttgtagctg caatttctca attaacattg attgctctag
    13741 gtgctttagg tgttgcatta gctcttattt acttgaacct ttctaaaatg ggtggttcat
    13801 caaataatgg aggcggaagc aactctggtg accctttagg cgacattttg aatgactatt
    13861 aatcttgaag gaggaaaata aaatggcaga agaaaaaatc aaattatcaa aaaaagatcg
    13921 tttagctgtt gcgtggcgct ctaccttcat tcaaggttca tggaactacg aacgtatgca
    13981 aaacggtggc tgggcatttt ctatgattcc agcaatcaaa aaattataca aaacaaaaga
    14041 agaacgttct gcagcattaa aacgtcactt ggaattcttt aatacacacc catacattgc
    14101 ttctccaatt ttaggggtta cattggctct ggaagaagaa cgtgcgaatg gcgcgcctgt
    14161 tgatgatgta gcgattcaag gggttaaagt aggtatgatg ggtcctttag ctggtgttgg
    14221 tgacccagtg ttctggttta cagtacgtcc aatgctaggt gcactaggtg cttcattagc
    14281 tatgggagga aatatccttg gaccaatcat cttcttctta ggttggaaca ttattcgttg
    14341 ggcattcatg tggtatacac aagaatttgg ctacaaagct ggttctaaaa ttactgatga
    14401 cctttctggc ggattgttac aagacgtaac aaaaggtgct tcaattttag ggatgttcgt
    14461 attagctgcc cttgtacaaa gatgggtatc aatcaaattc ttaccagttg tatcaactgt
    14521 aaaattagat aaaggtgctt acatcgaatg ggataaattg ccttcaggtg gtgaaggaat
    14581 caagagtgca tttgaacaag ttaataatgg cttagccctt tctcctgaaa aggtaacaac
    14641 attacaagac aacttagacc aattgattcc tggtttagct gcattaggat taacattgtt
    14701 atgtatgtgg ttgcttaaga aaaaggtttc tccaatcgtt atcatccttg gtttattcgt
    14761 agtcggtgtt gttggacacg tcatcggact tttataatcc ataaaaatat agctcgggcg
    14821 ttgtcccgag ctttttttat atagtatact gttcataaac aaatatctgg agggagaaaa
    14881 tggttcaatc aatcaataca aaagtagact tggtaattga tgctacttcg tttacgggtc
    14941 tgacagatta cgggcaaatc atgataggtg ataatggttt tgagttttac catgcgcgag
    15001 atagacgcaa atatatccaa attccatggg aagaagtgga ttatgtacta gcatcagtca
    15061 tgctaaaggg aaaatggatt cctcgatatg ccattcaaac gaaaaaaaat ggtacataca
    15121 cattttcttc caaagaacct aaaaaagtgc ttcgtgcgat cagagaatat gtagatgaag
    15181 atagaatggt acaatcattg agtttctttg atgtagtgaa acgtggtatt cgtagtatgt
    15241 ttaaacgcaa gtaaaaaata aagaaaactt ctaagaggag gttttcttta tttttttact
    15301 ttgcagaaga aaatatgaaa tagcaaaacc aattatttgt cccctttaaa tcccatatgc
    15361 taaaattgat tagcaaagaa ggaggttata ttatgagttg gttatggaca ttgattgttg
    15421 gagccgtgat cggagcaatt gcaggtgcga tcaccagtaa aggaaattcg atgggctgtg
    15481 taacgaatat cattgctgga ctagtcggtt caagtattgg acaagcgatt ttcggcgaat
    15541 ggggaccaaa agctgcaggt atggcactta ttccatctat tttaggcgca gtgattttgg
    15601 tagcagttgt ctcatttttc tttggaaaac gatcataagt ttttacaaaa tagtaaacta
    15661 aaaggagttg cagcgagact gtgactcctt tttggcttta tttatttaaa ataaaaagaa
    15721 gttttccgga aatttttatt taactgtcgt gtacgaagaa aagtttgcta taatggaaaa
    15781 aagcgtgcaa agaaagaggg agtttcatta tgatgctacg tgtagaaaaa ttgcgcaaaa
    15841 aaatgcaaga agaaaatttg gattcatttt tggttaccag tccgtacaat cttcgttact
    15901 taacgaactt tacaggtacg acaggattag ctgttattac tttggaaaaa gcatttttta
    15961 ttactgattt tcgttatacc gagcaggcgg cagcgcaggc tcaagggttt gaaattatta
    16021 aaaatgtcgg acctattttt gatgaggtag caaacttagt acgcaaagaa gaactgcact
    16081 cattagcttt tgaggaaaca acagtctcat ttttagaata ttcggtttta gaagaaatca
    16141 tcgatgcgga attagtacct gtttcacaga tgatcgaaga actcagagaa gtgaaagatg
    16201 aagaagaaat cgctattatc gaaaaagcat gtcatattgc ggatatggca tatgatcaca
    16261 tcctgaaaat gatccaaccg ggcatgactg agattgaagt cgcaaatcaa ctagactttt
    16321 atatgcgttc tcttggcgct tcaggtgttt cttttgatac gatcgttgct agcggattgc
    16381 gttcggctat gccgcatggt gtagcaagca aaaaaatcat cgaacaaggt gacttgatca
    16441 cattggactt tggttgctat tacgaagggt acgtttccga tatgacacgt acattcgcta
    16501 ttggtgatcc tggggaaaaa ttaaaagaaa tttatcaaat agtcttagat gctcaattag
    16561 cagttattga tgctgcaaaa ccaggaatga ctggtgtcca attagatgca gttgctagag
    16621 attatatttc aaaacatggt tacggggaag catttggaca ttctacagga catgggatcg
    16681 gtttagagat ccacgaagga ccaaacgttt cttctcgtgc agaaaagcaa tttgtaccag
    16741 gaaatgtgat cactgatgaa ccagggatct acttaccagg aatcggtgga gtacgtattg
    16801 aggatgactt gttgatcaca gaagatggaa atcgtgtgtt gactcgttca ccaaaagaat
    16861 tgatcatctt atagtttcat caatagaaga agtaagcgta aaaatcagtg ttcacagact
    16921 ttgttataga aaatcactcg atttaatgat acactataga agaactttta agctgtaaga
    16981 gataataaag ttgggtgttt tctccaattc atagcagttt gcagctgatc ggcggcagtt
    17041 ttcttaccac gtgatcacta tgccgcatca tagagaattc ggatgtatct cgtgcttagg
    17101 caaagggagg aataaataaa tggcagatga aaaaaatttg attttaaacg caaaccaaga
    17161 tttaggagag atcgtgatcg ctcctgaagt catcgaagta attatcggga ttgcagcttc
    17221 taaagtagaa ggcgtatacg gaatgcgcgg aacttttgcc agcaatgtca ctgaattatt
    17281 aggacgtgca gctcacggaa aaggtgttta cttagcaaac gaggaagatg gcttgaaagt
    17341 agatctttac tgttatctag aatatggtgt ttcagttcct aaagtagcaa tggaaatgca
    17401 ggaacgggtc agccagcaag tccttttcat gacggatatc gatttatctg aagtcaatat
    17461 ccatgtagta gctgttgttc ctgaaaaatt agaacaacca acaatcgaag aactttttga
    17521 agacgaagag gaagagaatg aataaagaat tatcaagaca cgagattcgg gaaatggcat
    17581 tgcaggcttt atttccatta gacttcaatg cagacctaac aaaagaagat gcgattttca
    17641 acgcaatcga attagaccac cgcgacatga tcaacgaaga tgaatcagag tttgttcctg
    17701 tttatcttga tacgctagtt ggcggtgtct gtgcaaaaaa agatgaattg gataaagtga
    17761 ttgaaaaaca tttaaaaaac aattggcaca tcaatcggat ctcaaaaatg gatttggtga
    17821 tcttgcgtat cgcgattttt gaaatgactt atgtgacaga tgtaccagcg gctgttgctt
    17881 taaatgaagc aatcgagttg gcaaaaacat ttagtgatga ccgttcacgt aaattcgtca
    17941 acggtgtttt atccaatgta ttgaaagaat tagaagctgg ggcgtaagtc ctagcttttt
    18001 tctatgaatc atcataaacc tgttataaat cgggaaaatt ctatggtaga atgaaaacac
    18061 aaaaaatatc tgggagtggt tagatggcag aattgattaa cggaaaagaa ttagctgaaa
    18121 aaatgcaggc agagattgct gaaaaaatcc aaaaattgaa agataatggt atccatcccg
    18181 gattagtcgt tttattggta ggggaaaatc cagccagcca aatctatgta agaaataaag
    18241 aacgtgtagc aaaagaaatc ggaatccatt cattggtaga gcgttatcct gagacgattt
    18301 ctgaagacga actacttgca gaaattgaaa aatacaatca agatcctagt tttcatggta
    18361 tattggtcca attaccattg ccaaagcata tagatgaaga aaagatcctg ttagctatcc
    18421 gccctgaaaa agacgtagac ggttttcatc cgatgaattt aggcagactc cttgcgggta
    18481 aaccggacaa gattccttgt actccatacg gcatcatgaa aatgtttgaa gcttattcta
    18541 tcgatccggc gggtaaacga gcagtagtta tcggacgaag caatatcgtc ggtaaaccga
    18601 tggctcagct actcttgatg gcagatgcaa ctgttactgt tgctcattct aaaaccgaaa
    18661 atctggctga actggcacaa gaagcagata ttttagtcgt agcaatagga cgtggacatt
    18721 ttgtcacaaa agaattcgta aaaccaggtg ctgtagtgat agatgtaggg atgaatcgtg
    18781 atgctaacgg taagctgatc ggtgatgtga aatttgatga agtggagcct attgcaggct
    18841 ggatcactcc tgtgccaaag ggtgtagggc caatgactat cacgatgctg atgtatcaaa
    18901 ccgtaaaatc tgccgaagct tttggagcag gtgaatagat ggcacaagaa tatttaactg
    18961 tcactacatt aacgaagtat ttgaaaagaa aatttgatgc cgatccttat ttagaacgcg
    19021 tatatttaac aggcgaaata tcgaatttcc gtttacgtgc caatgcccat caatatttca
    19081 gcttaaaaga tgaccatgca aaaatatctg ctattatgtt caaaggagca ttccaaaaat
    19141 tacgattcca gccaaaagaa ggaatgaaag tccttgtcgt tgggcgtatt tcattatatg
    19201 aagcgggagg ttcttatcaa atctatgtag agcacatgga gcctgatgga ataggtgctt
    19261 tatatcaaga attggaagaa cgaaaagaaa agctgatgaa ggaaggcctt tttcaagggc
    19321 ctaaaaaaat gctgccacgt ttcccaaagc gaatcgcggt ccttaccagt ccaagcggag
    19381 cggttatccg cgatatcatc acgacggtga aaagaagata tccaattgtc caattggttt
    19441 tgttcccaac agttgtacaa ggaaaccaag cagcggacaa tgttgtcagg aatatccaga
    19501 gagtagaaga gatgggcaat ttcgatacaa tgatcatcgg tcgtgggggt ggttcgattg
    19561 aggatttatg gccgtttaat gaagagcggg ttgctcgggc gatttatcaa gctaatacgc
    19621 cggtgatttc atctgtagga catgaaacag ataccacgat cgctgattta gtagcagatg
    19681 ttcgggctgc cactccaaca gcagctgcag aattagctgt tcctgttttg tcagaagagt
    19741 tgatgcgcat tcaagaacgg caagctagat tgcagcaggc gtttgtacgc cagatccagc
    19801 gcaaacaaga acggttcgag cgtgctcgac gttcctatgt atttcggcag cctgaaagat
    19861 tgtatgaagg tcagaccatc aaattagacc agttgaaaca gcgattatat caagctacac
    19921 agcaaattta tcatgcgaaa gaaaaacaaa cgatcgcatt aagccaccaa ttggaacaag
    19981 tggctccgct ttatcgagtt aaagcagctc gccaagaaac tgcttatcta gaaaaacgct
    20041 tagaagagaa aatccaacaa tatatgaaac aacagcagca gcgttttgct caagctgttc
    20101 aatctcttga tttgttgagt ccattgaaaa tcatgggaag aggctacagc tatacgacgt
    20161 taaatgatca agtagtaaaa agtgtcaccg agattcatca aggggatttg ctgacgatcc
    20221 attatcaaga tggaatcgtt aaaggacaag tacaagagat agacaaagga gaataaaaat
    20281 atggaaaatc caacttttga agagtcactg caagaattag aaaaaattgt catgcagtta
    20341 gaacaaggag acgttccatt agaatcagct ctagattcgt ttaaacgagg aatggaatta
    20401 agcaaacatt gccaagatac attagctaaa gcagaagaga ccttgacgaa aatgatgaca
    20461 gaatcaaatg aagaagttga ttttgacgga aacgaggaaa gctgagatga gattaactga
    20521 cttttcagct attcatctac ctgctgtaga aaaagaaatc ttgtcttttt tagatgagca
    20581 tacaacggat agaggactct atgatgcgat gagttattca gtgaaagcag gcgggaaaag
    20641 aatacgtccc ttattacttt taacggccgt tgcttccttt gatgagccta ttgatgttcc
    20701 cgtctatcaa gtagcagctg ctttagaaat ggtgcatacg tattccttga tccacgatga
    20761 tttgcctgcg atggacaatg atgatcttcg tagaggaaaa cctaccaatc ataaagtatt
    20821 cggcgaagca ttagctatat tggccggaga tggtttgctt acaggagcat tccagctaat
    20881 cagtatggca cacttaggta attctcctaa gcttctgctg cttcagcaat tagctgtttg
    20941 tgcgggatca caaggtatgg ttgctgggca agctgcagat atcgagggcg aatcgaaaaa
    21001 gctttcttta gaagaattag catttattca tgaaagaaag acagggcatt tgattcgtta
    21061 tgccttgctg gctggtggca tattagcgaa gcaacctgaa gaaatcttat tgctacttca
    21121 acgattagcc gaacatttag gtttagcttt tcagataaga gatgatctac tcgatgtgat
    21181 tggtacaacg aaaacattag ggaaaacagc tggtaaagat gaacgtatgg aaaaaaatac
    21241 ttacccgcgt ttattaggcc tagaaaagac acgtgaggcg ttggagattg agctgttatc
    21301 cgccaacaag atcatagaca aattagaaga ggacgttttt tcttttgatg gcgggctgat
    21361 gcgccagatg atcaagcaat ttgatgtgga gaaatgaggg aaagaatgga aaaagaacgc
    21421 gtagatgtat tagcggtcaa acaaggatta tttgaaacaa gagaacaagc caaacgttca
    21481 gtgatggctg gtttgattta caacgaaaaa aacgagcggt ttgataaacc gggagaaaaa
    21541 attccagtga gtagtgaatt aagagtcaaa ggtaaaaaac ttccttatgt ttctcgaggg
    21601 ggattaaaat tagaaaaagc actcaaagca tttgatctat ctgttgaagg aaaaacattg
    21661 ttagatattg gtgcatccac tggcggattt actgatgcag ctttgcaaaa tggcgcaaaa
    21721 atgagttatg ctttagacgt tggctacaat cagctagctt ggaaaataag acaagatcct
    21781 agagtcgtcg taatggaaag agtgaatttt cgttatgcaa aacccgaaga ctttacctta
    21841 ggaattccag aagttgctgt tatcgatgtt tcttttattt cactaaaact gatgctgcct
    21901 ccattacatg ctattttaaa agaagaggga gaagtgattg ctttaatcaa accccaattc
    21961 gaagcaggca gagaagctgt agggaaaaac ggaattgttc gtgaccctca gacccatcaa
    22021 aaagttttag aagacatttt gtcatttgcg gcacaaggtg gatatgatgt gctggaatta
    22081 agttattctc cgatcacggg gggagaagga aatatcgagt tcttggctca cttgaggaaa
    22141 gtacccgaaa gcggaacaat caattcagct attaatatgg cagaagtggt ttcaaatgca
    22201 cacgaacagt ttgaccataa ataaattgta actgtgaaaa tcaagtgaga agtatgcgga
    22261 ttcttcttta ttataccaag gaaataagct atcattgatt aagaagaata tgctaaggag
    22321 cgaagacgta atgagaaaaa aagatcggca tcgtttgatt actcgattgt tgagtgagca
    22381 agatatccga aagcaggaag aatttgttga aatcctgaaa agcaaaggaa tatctgttac
    22441 tcaagctacg atttccagag atataaagga actgaaactg atcaaggtac cggcttcaga
    22501 tggcggctac cgttatagca taccagctga aacaaacgaa gatgtaaata ctaaattgga
    22561 aaaactatta aaagacgctt tcgtggcagt tgaccaaatg gaaaaatttg ttattttgaa
    22621 aacattgccg ggaaatgctt cggcagcagc aaatttgatt gataaacgtt acaagaaaga
    22681 attattttcg attatcaatg atgacgataa tgttttgatg attacacgaa ctgaagacca
    22741 ggcagtttta ttgaagaaag acttcctgca ttacctttaa gttgaggagc gaatgtgatg
    22801 ctacaagaaa tcagtattac taactttgcg attattccgg aattgcggct ttcttttcac
    22861 gaaggaatga ccgcgctgac cggagagact ggtgcgggta aatccattat tatcgatgct
    22921 ttaggtctgt tagcaggagg aagaggttca agcgattata tacgtcaagg agcagaaaaa
    22981 tgtgtgcttg aagggttgtt tgaactacca aaacaagaag gattctctga actgatggtt
    23041 gaattaggga tcgaaacaga tgaggacaat ctgattgttc gacgggatat gtccttaact
    23101 ggaaaaaatg tttgtcgagt gaatggtcat attatcacat tagctaatct gagaagaatc
    23161 ggcagttatt tagtagatat ccaaggacaa aacgaacatc aggaactgct ccagcctgaa
    23221 tcacatcttg ctttattgga tcgttttgga gatgtagctt tccaacagaa gaaaaagagt
    23281 tatcagcaag aatatatctc ttatcgtgag ctggaaaaaa gggtacgaaa agtgcagcaa
    23341 aatgaaaaat cctatgttca gagaatagat atgctccatt tccagcaaga agaaatagct
    23401 gctgctgatt tgcaagtcgg agaagaagag aaattaaaag aagaaagaga aaaacttagc
    23461 aattatcaaa aaattgctga tggattagct gcaggttacg gagcactgac gaataatgaa
    23521 caaaacagtg tagatggtgt tggcttggcc gtttcagaac tgcaagggat cgcccatcta
    23581 gatgtggagt atgaagcaat ttatgaaaat atccaaagtg cttactattt gctgcaagat
    23641 gcaatcggcg atatgagtcg tcagattgat ttattggagt tagatgagag tcgtttagaa
    23701 gaagttacgc aacgtttaga attaatccga cagttgaaac gtaaatacgg cgaatccatt
    23761 gagtcaatat tggcttacta tgacgaaatc accgaagagc tagcttcttc tgatttttca
    23821 gaaggtcaat tggacaaaat gaaagaggaa ctagagcaaa aagagcttct acttcagcaa
    23881 caagccgcag atcttcatga agcgcgtaaa aaaatcgcaa aagaattgga aaaatccatt
    23941 ctgcatgaat tgaaaagtct gtatatggaa aacactgagt ttgaggtacg tttcttaaaa
    24001 gaagaaaata gacaattgaa tcatgatgga tttgaccaaa tcgaatttta cattacgacc
    24061 aatccaggag agccactgaa gcctttggtg aaagtcgctt ctggtggcga actgtctcgg
    24121 atgttgcttg ctttgaaaac tattttttct tctgagcaag gtgtgacaag tattattttt
    24181 gatgaagtgg atacaggtgt gagcggaaga gttgcacagg ccatcgcaga taaaatttct
    24241 caaatatcga aatactctca agttttgtgc atcactcatc tgcctcaagt tgctgcagtc
    24301 gccgactatc aatattatat tgtgaaagca gtgattgatg gacgtacgca aacttctgtt
    24361 tcagagttga aaacaaaaga aagagaagaa gaaattgcac gtatgctggc tggaagtgag
    24421 attacaaaac tcacactcga acatgcaaaa gaactattga aactcgcaaa aaggacctga
    24481 gccacctcgc agtggttcag gtccttttca gcagctgata gctatatttt atttttacat
    24541 gacactcatt acagcagtca atacaacaga tccaatcgtt aaaatcagca ttgtccaaat
    24601 gacaaatttt gttactttag caaaagtact tgtttgtttt ttttcacgca ttgttttcaa
    24661 cctcgtcatt aattagttga ttcaagtgta caatcttttt tccatttcca caagagggct
    24721 tttttataaa aacttccctt tttttaaata ataggtagtt acgatacaaa taaataatgt
    24781 taatagaact agccatataa aggcatcatc cctttcagca ataggtaact taatgttcat
    24841 tccatagata ctgccgacga ttgtcggtat agttaaaata atcgttaaag aagttaaaat
    24901 tttcataata ttattcagat tattcgatac gattgctgaa aaagtctgat tcatttgttc
    24961 tactagtttt aattgaatgc gagaagtagt cattgcctgc tctgtttcca ccaatacatc
    25021 acgtaaatga tttttcaaag catgattttc ttggaaaagt ttattttgcg ctagttcttt
    25081 caatgcatct aaattagcag aagtcgcttc tctgaaataa acgaggcttt tttggatatc
    25141 catgatttga taaagttgtt tgttttcagt ggatacttga agtttggctt ccaaagtatc
    25201 gcattgagat tgaagcgtag ctaaataact gttgtaagag agtgtgacct gccaaatgaa
    25261 ttgaaagaag atattgagat taggcgaaat atcacttttt ggaaaggtct ggctaaagac
    25321 tttctttaaa aacagtggtt catgattcgt aattgtgata agcttctttt tgggcgtcaa
    25381 aataatagag agcgggtatg tatccacttg aaaataaccg ctaggacttg ttttagcaaa
    25441 aggatattgt aacaataata acgctggctt tgtcaacttt gattgattga attcttctgt
    25501 acgggaattt tctgcatcgt ccaatatgga agtgatgtaa tctgacggaa tttcaaattg
    25561 atgtgtcagc tgatgaatct cttcttgatt aggacgttct acacaatacc agatcgtttg
    25621 gtcagtttcc tttccggtat tacgcagttt ctcattatct aatgtaaaat atttgatcat
    25681 gattttcctc ctgttgcctg tttcttttat tataacggat agggaattgg aatacatgga
    25741 atgtgtttgt aagatataga atataactgc ataaatttaa ataaaatgaa acagttgtgt
    25801 aaagtatata cagtatactt gaagcaacga taaaaaagga gtttacgttc atgggcacat
    25861 tcacaccact tatcttgttt tggtatattt acccggtaat cgttttgttt ggttgccaat
    25921 ttcttgtaaa attattttcg ttaaatcgtc gttttaaaat aaaagcccct gatttggcga
    25981 ttcctttttt gtggggcggt atgcatgcat tgtctagaaa tacagggaca atttctatct
    26041 taccgttttt ctttatttct gttttgctaa tgggaatttg tattgctgtt ttccaagcat
    26101 attattatga agaaattatt tatccgcgtt atttcaagat gacttggcgt ttggtttttc
    26161 tgttgacaat cgtcttgtac gctgtcttga tcattgtgaa catactttct tacctatgaa
    26221 aaaaatagaa aagctgtaaa aagtctttta aaaggctttt tgcagcttga tttttaaaaa
    26281 aatgtttatg aataaaaaaa gttgttcccg gatttcccag aaaaggtggt agaaagtggg
    26341 ggattgtggt agactaattt tagttagtgg aggaatgggg ggctttcaat gttgatgggt
    26401 gaattccaac ataatattga tgcaaaagga cgtttaatcg tgccctcaaa acttcgtgaa
    26461 gaacttggcg aaaagtttgt tctgacacgc ggattggatg gctgtctttt cggctatccg
    26521 atgagcgaat gggaaaatct ggaagctaaa ctgaacgaaa tgccgttggc taaaaaagac
    26581 gcacgtactt ttgtgcgatt cttctattcg gctgccactg aatgcgaact tgataaacaa
    26641 ggacgaatca atatacccag cacgttaaga aattatgcag ctttgacaaa aggttgcgta
    26701 gtcatcggtg tatctaaccg aattgaaatt tgggatgaga cacgatggca agatttttct
    26761 gcagcagcag aagagaactt tgacgaaatt gctgaaagta tgattgattt cggactataa
    26821 gaataggaag aggctgacta atgactgaaa catttcaaca ctatacagtc atgttgaaag
    26881 aaacggtaga tggattgaac atcaaaccgg atggcgttta tgtagactgt acactcggcg
    26941 gtgccggaca tagtgaatat ttattaagcc aactaagttc taaagggcat ctgtatgcgt
    27001 ttgaccaaga tcaaaaagca atcgatcacg ccaagctgcg tttagcttct tatgtcgaac
    27061 aaggtatggt cacatttatc aaagcgaact tcagagaatt agaagaacgc ttgagtgagc
    27121 atgtagataa ggtagacggc attttgtatg atctaggggt ttcctctcct cagctagatg
    27181 aagcagaacg tggatttagt tatcatcaag atgcaccgtt ggatatgcgc atggatcagt
    27241 cagctccttt atccgcttat cacgtaatta atgaatattc ctaccatgaa ttagtaaaga
    27301 ttttcttccg ctatggcgag gagaaatttt ccaaacaaat tgctcgtgaa atcgaacgag
    27361 tacgaaaaac aaaaccaatc caaacaactg gtgagcttgt cgaaatcatt aaacaagtca
    27421 tcccagctcc cgcaagaaga aaaggcgggc atcctgcaaa aagaattttt caagctgtgc
    27481 ggattgcagt aaatgacgaa ctcggtgccg aagaggcctc tttagaacag gcaatccggt
    27541 tattgaaagt caatggaaga atcagcgtaa tcacattcca ttcattggaa gacagaattg
    27601 tcaaaagtat gtttaaagaa tatagtacgg tacaagatct accaccggga cttcctgtca
    27661 tacctgacga attccaacca gaactgaaag tcattactcg taaaccaatc cttccttcag
    27721 aggaagagct aacagaaaac aatcgatcac gcagtgcaaa gttacgtatt gcagaaaaaa
    27781 taagaatgaa agaggagtag aatgatggca gaattaaaga aaatgcaaga ttacgaatat
    27841 gatttacctg aattggtgga tcagccggaa caacaaatgc ctgattcttc ttcgaatcaa
    27901 gaaatcattc ttccacaatc accggcaaaa cgattaaagc agatttctgc tttggaaaaa
    27961 attgctgtgg caagcgtggc gattgctatt gttgctttat gtgttttaac agttatgctg
    28021 cgcacaaata tcagcggagc tgaaaaagaa atcacgtcaa tacaaacaga aatcaatgat
    28081 aaaaagcaag aaaaaacgag tttagaacaa gaaaaaaacg aactttctcg tactgaacgg
    28141 attaaacaaa tcgcagaaga aaaaggattg tctattaatg acgacaattt aaggagagtg
    28201 aagtaaatga gtcttaaaaa taaaattcgg cggtttatgg aaaagaaaaa tctaaatccg
    28261 atgaacaatc gcaaaaaagt aggtatcatt ttatttgcta cgagtattgg attgttcttt
    28321 ttatttgccg tccgtttctc gtatatcgtt attggaggtc atgttgctgg tacctcatta
    28381 gctgaaaaaa caaaacagtt gtaccaagga agtgaagtag taaaagcaaa aagaggaacg
    28441 atttatgatc gtaacggtgt ggcgctcgca gaagatgcct cctcttattc aattaaagcg
    28501 atactctcaa aaacatatac ctctggggat aaaaaactgt atgttgaaga aaagaatttt
    28561 gataaaatag cagaaatcct gcataagaat ctttctatag acaaaaaaga tgcactgaat
    28621 attttagagg acggcgcaaa aaaagagctg tatcaagttg aatttggtag ctatgggaaa
    28681 aatatctccc aagaaaccaa gcaaaacatc gaagcggaca tgaaaaaaga aggtgtcgct
    28741 ggtctttatt ttgtcgacca tcaggctcgg atgtatccaa atggcgtctt ttcttctcat
    28801 tttattggat acgcagttcc agacaaagat gagaatggct tagttggtaa actaggtttg
    28861 gagtctgctt acaatgatat cttgagcggt aaagatggta agattattta tcaaaaagat
    28921 aattttcaaa atcctctgcc aggtacagtg gcagaagaag aaaaagctgt cgacggacaa
    28981 gatatctaca cgactttaga cagcagacta caaagttatt tagaaacact gatggatcaa
    29041 gtaaatgaag aatatcagcc agaagaattg acagcagtcc tgatgaaagc aaaaaccgga
    29101 gaaatcttgg caatgggaca acgacctact ttcaatcctg aaacaatgga aggattgact
    29161 ggaaaagatg ctatctggcg taatttcttg gtacaagata gttatgaacc aggatcaacc
    29221 atgaaagttt tcactactgc agctgctatc gaagaaggag aattcaacga gaatgaaacc
    29281 ttccaatctg gaaaaatcca agtagaagat gctacgatca atgaccatga ctttggtgaa
    29341 aaaggtgtgc tgaccatgcg tcaagctctt tcatggtcaa gtaacgtcgg gatggtcata
    29401 ctggaacagc gattaggcgg acgatggtat aactatttac aaaaactggg atttggacaa
    29461 agtactcatt ctggattaga tgatgaagta aacggtgctt tacctacatt aaatattgtc
    29521 gaccgagcaa tgagtgctta tggacaagcg gtaggtgtga cgaatttcca aatgatgaaa
    29581 gctttcactt ctattgcgaa taacggtaca atgattcaac ctcgatatat cagcaaagtg
    29641 gtggatcccc aaactggaga agagcgaaca actcaaacag aagttctagg gcaacctttt
    29701 tcaaaagaaa caacagaaaa agtccgtgaa tatatgagag atgttgtcga aagcgaaaac
    29761 tacggtagtg cttatggtgt atatagtgta cctggataca atgtatcggc aaaaaccgga
    29821 acagcccaaa tcgcttctga tacaggggga tatcaaacag gagatacagc ctacctgtat
    29881 tcgattgtgg agatggttcc ttctgaagat ccagactatg tcttgtatct aacaatgaaa
    29941 caccctaaga catatgatcg aatggcattg gctaaaatcg caaatccatt gatgaaacgg
    30001 gcaatggatt ttaaagaaac tgaagaagat tcagatacag aaacaaaaac agaaaaagta
    30061 tccgtagccg attatcgtaa tcttgaagcg gacgttgcag cagctgatgc tcaaaaaagt
    30121 ggactgcaac ctgtagtgat cggtaatggt aaaaaagtac aaaaacaatc tactgccaac
    30181 ggtgatcagt tgatctctgg agaaaaactg atcctatata ctggtggtga taagctgatg
    30241 cctgacgtaa caggatggtc aaaagcagat atcatgaagc tggggaaaat cctcggtatt
    30301 gaagttagtt ttgatggaga tggttattgt gtcaaacaag aacttgctcc atatgaaaaa
    30361 atcactgaag acaaacttag ttttacttta gaagaataag aagagaaata ggagagaaaa
    30421 gagcatggaa tggacacaag cattgattcc cattgtcagc agttgtgcaa tgacaattgc
    30481 cgcaatgccg ctatttattg gttattttca aatgaaaaag caaggtcagg cgattcgtga
    30541 ggagggacca aagtggcaca atagcaaagc cggaactcct acaatgggcg gcttagtgtt
    30601 tctgatcggc tctattttga caggaatttg ggttggagct tggcaaaaac agctaactcc
    30661 tactcttttc atcttgcttt ttgtattagc gttatacgga gtaatcggct ttcttgatga
    30721 ttttataaaa atattcaaga aaagaaacat gggactgaac tcgaagcaga aattgattgg
    30781 acagattcta gggggaatca tcttttatct tgtttaccgt tctgaaggtt atccaggtgt
    30841 attgaatttc ttcggactag atctaccttt aggaatcatt tatggtattt tcgctctctt
    30901 ctggcttgtt ggattttcaa atgcagtaaa tctgacagat ggcatcgatg gattagttgc
    30961 tggcttagga agtatctctt ttgcagctta cggtctaatt gcttggcatc agcatcagta
    31021 tgatgtatta atcatttgct taagtgtttt aggaggttta ctgggtttct tcgtctacaa
    31081 cagaaaacct gccaagattt ttatgggaga tgtcggttca ttagcgttgg gcggactttt
    31141 agcggcaatt tctataatgc taaaccaaga atggacattg cttttgattg gtttgatcta
    31201 tgttatggaa acagcaagtg tgatgcttca agttacttcc tttaagctta caggaaaacg
    31261 aatttttaaa atgtctccaa ttcatcatca ctttgaaatg tgcggatggt cggagtggaa
    31321 gattgataca gttttttggt tgatcagcat tgtgacttcg ttgatcacat tatggatcgt
    31381 ttggtaggag atgacgggaa atgaaaaaaa tatcaacata tgaaaataag aaagtgcttg
    31441 tcttaggact cgcaaaaagc ggagtaagtg cggccaaatt attacatgaa ttgggcgcac
    31501 ttgtcaccgt taatgatgga aaaccttttg acgaaaatcc ggaagcacaa gagctgcttt
    31561 ctttagggat aaaagtaata acaggtagtc atccaatcga attgttggat gaagaatttt
    31621 cattgatggt caaaaatcca gggattccct acagtcatcc tttagtagca aaagcccaag
    31681 aaatgggtat tccggtaatt acggaagttg agctagctta cgaagtagcg gaatgcccaa
    31741 ttattgggat tacaggaacg aacggaaaaa caacgacaac aacgatgaca ggactactac
    31801 tgaatgcagg agcagatcaa ggaattgcac gtttagcggg taatattggg tatccagcaa
    31861 gtggtgtagc gcaagaagca aaatcagaag ataaaattgt gatggaattg tctagcttcc
    31921 aactcatggg aatcacagat ttccgccctc atatagcggt gattaccaat atctatgaag
    31981 cacatattga ttatcatggt acaagaaaag aatatgtcaa agctaaatgg aaccttcaaa
    32041 aaaacatgac agaaaaagat tatctgatcc ttaactggaa tcagtcagaa ctacaagaat
    32101 tagcgcaaag aacaaaagca cgcgtactgc ctttctcgac aaaagaagtg ttggaagacg
    32161 gtgtgtatgc tgacgattac tcaatatact ataaaaaaga aaaaataatg gaaatatctg
    32221 aacttggcgt accaggtaag cataatgtag aaaatgcact agctgctatt tctgtagcaa
    32281 aattgtatgg tatatcaaat gaagctatac gagaaacgtt gcattttttc catggcgtac
    32341 cacatcgtac gcaatatgta ggagaaatcc aaggcagaaa attttataat gattcaaaag
    32401 caaccaatat tttagcgact aaaatggctc taagtggatt tgaaacgtct aaggtcgtgt
    32461 tattggctgg cggattagac agaggaaata catttgatga attaattcct tcattaaaag
    32521 gaatcaaagc aatggtcgta tttggccaaa caaaagaaaa gttgatggat gctggaaaaa
    32581 aagcaggcat cgagacaata gtaacagccg attctgtaga acaagcagtt cctttagcat
    32641 tagaaaacag tacagatggt gatgtagttt tattatcacc agcgaatgcc agctgggatc
    32701 aatacccaaa ttttgaaact agaggaaaca gattcatgga agctgtgaac cgattaaaat
    32761 agaaaaagta gaagcgagcg ataaaaaatg aaaattttgg ttacaggcgg aggaacaggg
    32821 ggacatattt atccagctct tgcctttgtc aattatgtaa agactcaaga accgaatgct
    32881 gaattcatgt atgtgggagc aaaacgaggt ctagaaaaca aaatcgtccc tgatacagga
    32941 atgcctttcc ataccttgga gattcaagga tttaaacgaa aaatttccat gcataacatc
    33001 aagacggtcc gattgtttct taagagtatc cgtcaagcaa aaaaaatcct cagtgatttt
    33061 caaccagata tcgttatcgg tactggagga tatgtttccg gagcggtagt gtacgctgca
    33121 gccaaaatgg gtattccaac agttatccat gaacaaaaca gtgtaccagg tgttaccaat
    33181 aaatttttaa gccgatatgt ggatcggatc gctctttcat ttaaagatgc ggcttccttt
    33241 tttcctgaaa acaaagcagt tcttgtaggt aatcctcgag cacaagaagt agcagatact
    33301 aaaaaatcag atattttgaa aacatttgat ttggatccag aaaagaaaac agtcttgatt
    33361 tttggcggta gtcaaggagc acttaaaatc aatcaagcag tatcagtttt tttaagtgaa
    33421 tatattcctt cttcttacca agttttgtat gcttcaggag atagatatta tgaagagatc
    33481 ctaaataaaa taaatcctga aatacaaaat attagtgtcc agccttatat caaaaatatg
    33541 gcagaggtca tggcttccag tgatctgctg gtggggcgtg ctggtgcaac ttcgatcgca
    33601 gaattcacag ctctggggtt accggcagtg ttggttccca gcccatatgt tacgaatgat
    33661 catcagacta aaaatgcaat gagtcttgtt cacgcaggag cagcaaaaat gattgcagat
    33721 aatgaactaa caggtgaatc actaagtcag acagtcaacg aaatcatggg tgatgaagaa
    33781 ttgcaaaagc aaatgtgccg agcttctaaa gaacaaggaa tccctgatgc ttcaaaacgt
    33841 ctttatgact tagtaaaaca aataatcaaa aaataaaggc ggtggtctta gtgagtaaga
    33901 aaaaagaacc aaaaaaattg tctcatccgt cttctgatga aaacaatttg actccttggc
    33961 aaaaggctaa ccgaaaatat ctggcagaac aagagatgaa aaaccaagag ccaaaaaaag
    34021 aagacataac attagataca cccctttcag attctgaaga agaaaaaacg gttcaagagg
    34081 aacagcaaga agaaagccag tccgagaaaa aaatcgaatt ttttgaagag atcaagcaaa
    34141 agaaaaacgg tggaccatat aacggttctt ttttgaaccg gctgcccaat ttaaaaagtc
    34201 aacggcacaa agtactattt cgtcggttag ctttgatcat cactgtattg ggtataccgc
    34261 tgattttttt gatctattat gtttctcctt atagcaaatt acaagcagtt gcagtatcag
    34321 gcaataagac agtcaacagc caagaaatca tctctgatac aaaattgtca ttaggagaaa
    34381 atgtttgggg acagtatttt catcgatcta cttatatcga tcgccttaaa aaagcacagc
    34441 caagaatcga aacagcaaat atacatttca aagggatgaa tgaattcgat ttggatgtaa
    34501 cagaatataa agagattgct ttgatcgcaa aaaacaatca atactaccca gtgattgaaa
    34561 atggaacagt attagatgaa aaagtagcaa atcctacaaa aaatctccct atcttggaag
    34621 agttcaaaga ctctgcaaaa atcaaagaat taacaaagca atacaatcag ttatcatcag
    34681 aattacaaaa agcaatttct gaaatcaagt acacgccaag agcaagcaat aaaaatctga
    34741 tccaattgaa tatgaatgac ggcaatcaag ttattgtaaa tatcaataat cttgcgaacc
    34801 aaatgaaata ttattcgcaa gtagccaaag atatggatga aaaaggtgtg atcgacatgg
    34861 aagttggtat cttctcgcat ccttacggta gcactcaaga aacggaagaa tcgggccaat
    34921 cggaagaaac aactgaaagt gaagaaaatg cggatcaaac aaacgaatca agtgaagagg
    34981 cagaaacgca aaaagcacaa acacctggat cgtctagcac aaacggatca tctgattcaa
    35041 atgattcaag tgaaacaagt caaatagaag ataatccaag tacaactccg tcaagtttaa
    35101 atgaaaattg ataaaacaac tttaaaaagt aagaatgtac tttctaaaaa ccagtaattt
    35161 atggtagaat tggaagcagt gaatatatct attaataagt atattttaaa acggacgcta
    35221 gttgttcgct tgtatatgga atagtaagta ggagggaatc ccattcatgg caaaaacagg
    35281 aatgtatgta ggccttgata ttggaacgac atctgttaaa gttgtcgtgg ctgaatatat
    35341 cgacagccaa atgaatatta ttggagtagg aaacgcaaaa tcagaaggga ttaaccgagg
    35401 cattatcgtt gatatcgata aaacggtcca agcgatacaa cgagcagtac gacaagcaga
    35461 agaaaaagca ggtatccaga tcaaaggcgt aagtgtcggt ttgccagcaa acatgcttga
    35521 agtagaaaat tgccagggaa tgattgcagt taacggagat tcaaaggaaa tcaccgatga
    35581 agatgtcaga aatgtggctt cagctgccct tgttcgttca atacctcctg aacgtcaaat
    35641 cgtgtcaata ttgccacaag attttactgt cgatgggttc gagggaatca aagatcctcg
    35701 tggaatgatc ggcgtaagat tagaaatgta cggtctgttg tttacaggac ctaaaacgat
    35761 catccataac atacgtaaat gcgtggaaaa tgccggatta atcgtcaacg aaatggtgat
    35821 tactccttta gcgctgactg aatcaattct ttctgacgga gaaaaagatt ttggtacgat
    35881 cgtcattgat atgggtggcg gccaaacaac aacggctgtt atgcatgata agcaattgaa
    35941 gtttaccaat cttgaccaag aaggtggcga atttgtcact aaagatatct ctattgtatt
    36001 aaatacgtca tttaacaatg cagaagcgtt gaaaataaac tacggggatg catacccaga
    36061 acggacatca ccagatgaag aatttccagt agatgtgatt ggtcagtcag aaccagtgaa
    36121 agtcgatgaa cgctacttgt cagaaattat ttcagctcga atggaacaga ttttcaacaa
    36181 agcaaaagat gcattggacc aaatcgaagc attagagttg ccaggtggcg tcgtattgac
    36241 aggcggagct gctagtcttc ctggtgttgt ggacttggca caagaaatct tcggcgtaaa
    36301 tgtaaaattg tatgttccaa atcacatggg gctgagaaac ccggtattta caaatgtaat
    36361 aagtatcgtg gattattcag caaacttgag tgaagtgtat caattggcaa aaattgctgt
    36421 tacgggtgaa acctcagcag ctcgtcaaat ggtagttgaa caagaaacaa caaacacata
    36481 tgagagctat gaagcacctg aagaaacaat ctacgatgag ccggaaccaa aagagtccgg
    36541 agaaaatgta aaaaataaaa tcaagggttt ctttacaaat atttttgatt aattcatcct
    36601 gggaggaata agatatggaa ttctcaattg ataataatat caatgacggc gcagtaatca
    36661 aagtcatcgg agtcggtggt ggcggtggaa atgctgtaaa ccgaatgatt gaagaaaacg
    36721 ttaaaggtgt tgaattcatt acagccaaca cagacgtgca agcattaaaa aattcaaaag
    36781 ctgaaacagt tatccaatta ggccccaaat atactcgtgg tttaggtgct ggttctcagc
    36841 cagaagttgg acaaaaagcg gcagaagaaa gtgaacaatc cttacgcgaa gctttagacg
    36901 gtgcagatat gattttcatc actgcaggaa tgggtggagg aaccggtaca ggtgctgcac
    36961 caatcgttgc aggtatcgcg aaagaattgg gcgcattgac tgttggtgtc gtgacacgtc
    37021 cattcacttt tgaaggaccg aaacgtggcc gttttgctgc agaaggtatc gctcgtttga
    37081 aagaaaatgt ggatacatta ttaattatct caaataaccg tttattagaa gttgtagata
    37141 aaaagacacc gatgcttgaa gctttccgtg aagcagataa tgttttacga caaggtgtac
    37201 aaggtatctc tgatttgatc acagcgccag gttacgttaa ccttgacttt gctgacgtga
    37261 aaacagtgat ggaaaaccaa ggtacagcat tgatggggat cggtgtggct agtggagaag
    37321 atcgcgtagt agaagcaacg aaaaaagcaa tctcctctcc attgcttgaa acatctattg
    37381 atggagctga acaagtactt cttaacatca caggcggttt ggatatgaca ttgttcgaag
    37441 cacaagatgc ttcagatatc gtagcaaatg cagcaactgg cgatgtaaat atcattctag
    37501 gtacatctat caatgaagaa atgggcgatg aaatccgtgt gacggtcatc gcaacaggta
    37561 tcgatgaatc aaaaaaggaa cgcaagtcta gccgaccagc tagacaagca caaatgcaat
    37621 cacctgctca aaagactgta ttagatatgg atcaagctaa accaacttct tcagaagaag
    37681 aaaacagttt tggcgattgg gatatcagac gtgaacaaaa tgttcgtcct agagttgatg
    37741 attccaattt tgacaatatc gaaaaaaaag aatttgatac attcaaccgc gaagaaacaa
    37801 aatctcatgg cgatgatgaa ttaaatacgc caccgttttt ccgtcgtaaa aaataaagga
    37861 gaggaagagc acatgattgc tgacaacttg cagaaaatca agcaagaaat tcaggattcg
    37921 tgtgctcttg ttcatcgtga tccgaaagaa gttacattag tagctgtaac aaaatctgtt
    37981 gaatccgctc aagctgaaga attggttaga gctggcgtta tgaattgtgc agaaaaccga
    38041 gtagataaat tattagaaaa gaaacaagat ttatttgatt ttcctgaaat aaagtggcat
    38101 ttaattggta atttacagcg cagaaaggta aaattgattg taaatgaaat tgattacttt
    38161 catgcgttgg acagtttaag attagcagaa gaaatccaga agcggttaga gaaagaatta
    38221 tcctgtttta ttgaagtaaa tgtttctggt gaggaatcaa aacatggaat ttcaccagat
    38281 gagcttttac cgtttgtgga atctttagct gcctgcacaa aaatcaaggt tgttgggttg
    38341 atgactatgg cgcctaaaga agcttctgat gagcaaatcc ataaagtgtt tggtacgctg
    38401 aaagaattgc gtgatcttgt tcaagcaaaa ggttatgccc atgcaccatg tagtgaatta
    38461 agtatgggga tgagtcaaga ctttcaaatt gcgattgaag aaggtgcaac atttatccgt
    38521 gtaggaacag cgctattcaa agacgaataa aggaggaaca aaaatgccgc ttttaaacag
    38581 aggagcaatt gctaattttt tcggattagc tgatgaggaa gagtacgaat accaagatta
    38641 tcctgaaaca acaaaaaagg ctgtacagcc aactaaaaaa aatacaacac agaatcaatc
    38701 aactcattct gtatctgctg cgaatactca tgaaaaacaa aaaacggcga cttcacgtcc
    38761 tgtaacgcat gaaagtattc agccggctga aaagaaaaaa gtaattgaac tacatcaatc
    38821 acctacaaaa actgtagcga aagaaagaac agcttcaaga acctctacac aacctaaagc
    38881 aaatcttgct ggaaaaatca ctgtaatgga accaagagct tattctgaag ctatggcgat
    38941 tgctaaacga atcattgctg gagaagcaac cttagtgaat tttcatttag tagaagaaaa
    39001 acaagcgaga agaatcgttg attttctaac aggaacagtt tatgcactag atggagatat
    39061 caaacgtgtt ggagatgaga tttttctttg tacaccgact gggatggaga ttgacagttc
    39121 aaccgctcaa tcttttgcag atgcgaattt gtttgatctg taagaggagg aactacgatt
    39181 tatactattg cactattact tcatttactt caacgggcag cctatttcta tagcattatc
    39241 ttgatggtat atgcattgct ctcttggttt ccaggcgggt atcaatcagg gctaggacga
    39301 ttattagcta agatctgcga accgtatatc agtttgttcg atcgtctgcc tttgaggatt
    39361 ggacccttgg atttcacaat tttaggggca atcctgatct tgaacttagc cgtacaaggt
    39421 ttagcacaga tcgttatatg gataactgtc catttagttt attgattgaa gcaacaaaat
    39481 ctttattctc agaatagata ggaggggaaa attttggatg caaatgtata ccagcacttt
    39541 cgggcagatg aacgtacatt tatcgattcg gtaggcgatt ggattgaaca ggttcaagga
    39601 caatatgcac cctatctgac cgaatttctt gacccaagac aatcctatat tttagaaaca
    39661 ctgattcgac aaagcagtga tttgcgtttc atgttttatg gcggatatga acaggcagaa
    39721 agaaaaagat gtttgatttt ccccgattat tacgaacctg tagaggaaga ttttgaaaca
    39781 gcattgtatg aaatccatta tcctagcaaa tttgccagcc taagtcatgg gaaaatcctt
    39841 ggaactttag tgggaacggg gatcaaacgc tcttactttg gcgatatcat ctcggacggt
    39901 gatcgctggc aagtatttat tgcaaatgag gtggatcatt ttgttgctgc acaagtaaca
    39961 aagattggaa aggttgctgt acgcttggaa ccaatcaaat acacagaaat gattatgccg
    40021 aaagatagct ggacacaaga aagaggaaca gttagttcca tgcgactaga cagtgtgatc
    40081 tctgagattt ataatatttc cagacagcgg tccaagcagc tgatcgaagc tggtaaagta
    40141 aaagtgaact ggacagaaaa tacaagacct gattttgtac ttgaactatt agatattatt
    40201 tcagtcagag gttatggcag agtccagatc caagaacttg aggggaagac gaaaaaagaa
    40261 aagtacaggg tactgttcgg tgtattacgt aaataaaata aaaaggtggt ttactcatgg
    40321 ctttaactcc attagatatc caaaataaga cattcccgac aaaaatgcgg ggatataatc
    40381 aagacgaagt agatgatttc ttagatttag ttgttcgtga ctatgaggaa ttgactcaaa
    40441 gaaatcgaga attagaaaaa gcagtcaaac attctgaaga aaaacttgag tacttcaatg
    40501 aattaaaaga tgctttgaac caatcaatca tcgtagctca agatacggct gataaagtaa
    40561 aaacaagtgc aagcaaggaa tccgaagtga tcgttacttc tgcacaaaac aaagcagatg
    40621 agttagttgc gaacgctgaa aaacgtgcac atcaattaac aactgatgca gaagaaaaag
    40681 caagaaaaat cttgacagat gcaacagaaa aagcaagaca gcttgcgaca gaaactgaag
    40741 atcttaagaa aaaaacacga gtattccatc aacgtatcag cttgatgctt gagtctcaat
    40801 tagaacaagt gaaaagtccg gaatgggatg aaattttaca accattctcc agctacgtga
    40861 ctgacagcca tgaagtgatc aaagaagttt tagcaaaaca gcttgacaat gaaaatgata
    40921 ctgatgtaaa ctcagacaca ggagtcatag aagcacctat gacggcattt gatacacagg
    40981 ctattgatat ctcgatcgtg cctggtgaaa atgaaaacga gtagaacaga aaagcacttt
    41041 gttattctta aagcgagccg atgagagtgg aagttcggta agacactgca tggtgaaaga
    41101 tcctctactt gagacctgct tttccgaaat tagagtaaga agcagcggct gacctcgtta
    41161 ttggtcacag agagtttgca ctagatagat gcaactaaat ttgggtggta ccacggcatg
    41221 ttcgtccctt gcggctgaac atgctttttt gtgtccggaa aacaaataaa ggagtgtatg
    41281 gttgaatgaa aatgaaagaa accttgcaat taggaaaaac aaaattccct atgcgtggta
    41341 atttgccaaa ccgagaaggc gagtggcaaa aagaatggga agaaaatcga atctaccaaa
    41401 aaagacaaga gttgaacgaa ggaaaaccta gctttgttct tcatgatgga cctccatatg
    41461 ccaatggtaa tatccattta ggacattcat tgaataaaat cagtaaagac attatcattc
    41521 gttcaaaatc aatgtctggc tatcgtgcac catatgttcc aggatgggat acacatggat
    41581 tgccgattga acaagtattg gctaataaag gcgtgaaacg taaagaaatg tccatggcag
    41641 aatacttgga aaaatgtcgt gaatatgcac tttcccaagt agataagcaa cgagcagatt
    41701 tcaaacgcct aggagttgca ggagattggg aacatcctta tgttacatta gatccttctt
    41761 atgaagctgc acaagtacgc gtatttggta aaatggctga aaaaagctat atttacaaag
    41821 gattgaaacc aatttactgg tctccgtcaa gtgagtcttc tttagcggaa gctgaaattg
    41881 aatataaaga tgtaaaatct ccatctattt ttgtagcttt caatgtcaaa gacggcaaag
    41941 atattcttga tgaagataca gcttttgtca tttggacgac aacaccatgg acattgccag
    42001 caaaccaagg tattgctgta aatccaaaat ttacgtatgt attggtggaa gccgatggcc
    42061 gtaagtttgt cgtagcgaaa gatttgctag aaacagtcca atcagaaatc ggttgggaaa
    42121 atgtaacagt tctaaaagaa tttgctggac aagaaatgga atatatgact gcaagtcatc
    42181 cattctatga acgtgaatca cttgtgattt taggcgatca tgttacttta gacgctggta
    42241 ctggattagt ccatactgct ccaggacatg gggaagatga ctatatcgct ggtagcaaat
    42301 ataaactatc tgtagtgtca cctgtagact caaaaggatt gtttacagaa gaagcacctg
    42361 gatttgaagg tatcttttat gacaaagcaa atcctatgat cactgatcta ttaaaagaaa
    42421 aaggagcttt gctgaagcta gatttcttta ctcatagtta tcctcacgat tggcggacga
    42481 aaaagcctgt gatctatcgg gcaactccac aatggtttgc atctatcgat aaattccgtc
    42541 agaatatttt ggatgaagta gaaaaagtag agtgggttat cccatggggt aaaacacgtt
    42601 tgtataatat gatccgtgac cgcggcgatt gggtaatttc ccgtcagcgt gcatggggag
    42661 taccacttcc gattttctat gctgaaaatg gagaagcaat catcacacca gaaacaatcg
    42721 aacatgtggc aaaattattt gctgaacatg gatcaattat ctggtttgaa aaagaagcga
    42781 aagaacttct tcctgaagga tttacccacc caggttctcc taatggcgaa tttacaaaag
    42841 aaaaagatat catggatgtc tggtttgatt ctggttcttc tcatgaagct gttttacgtc
    42901 agcgaccaga attatcattc ccagcagata tgtatttaga aggatcagac caatatcgtg
    42961 gctggttcaa ctcaagtatc acgactagtg tggctatcaa tggtgtagca ccatacaaat
    43021 cagttatttc tcaaggattt gctttagatg gtgaaggccg taagatgagt aaatctttag
    43081 gaaacatcat tgcaccagaa aaagtgatca aacaatttgg tgcagatatc cttcgcttat
    43141 gggtatctag tgtagattat gaagcagatg ttcgtgtttc tatggatatc ttaagtcaag
    43201 tggcagaagt atatcgtaaa atcagaaata cgatgcgttt cttattagcg aatacagaag
    43261 atttcgatcc taaaaaagat actgtttcgt acaatgattt acgttctgta gacaaatata
    43321 tgaccgttcg attgaaccaa gtaatcaaag aaatccgaga agaagggtac gacaaatata
    43381 acttcatgca tatttaccgt acagttatga acttcttgac ggttgatcta tcgtcattct
    43441 acctggattt tgctaaagat gtagtttata ttgaagcaga agatgattat caacgtcgtt
    43501 gcatgcaaac tgttttctat caaacagctg tagctttgac aaaattattg actcctatca
    43561 ttccgcatac agcagaagaa atctggtcat tcctgaaaga agaagaggag tacgttcagt
    43621 taagcgagtt tcctggttat gaagagtttg caaaccaaga agaattgatg gatacctgga
    43681 ctgctttcat ggacttccgt gataatgtct taaaagcatt ggaagaagca agaaacagca
    43741 aattgattgg taaatctttg gaagcaaaac taactgttta tccaaaacaa caagttcgtg
    43801 aaatgttaaa agctttggat gcagatattg cacaattatt gatcgtttca ccagactact
    43861 ttgaagttat ggcagcagat gaacaagtgc cagataacgc tatggtattt gatgatgttg
    43921 ctattacagt ggaaaaagca gacggggaaa cttgcgatcg ctgtcgccaa gttcgtaaag
    43981 atgtaggagt agatgaaaaa cttcctcatc tatgcggtcg ttgtgcaaaa atcgttgaag
    44041 acttctatcc tgaagctgta gctgaaggat tcgaagaaaa gtaaaaggga aaagggggtg
    44101 tgacatgttc tttgtcacac ccccttttgt tatcaatcgt ttaattttcc acgttcacga
    44161 taccagttat ctggttgcca gatccattcg aatccgtctt tttcaagtag ttcgaaagct
    44221 gctttaggtc ccattgatcc agctttgtag ttgggaaaat ccggttgtgt ttggtcccaa
    44281 gcttttcgaa tgacatccac gatatgccaa gattgagcga cttcttccca atgagagaag
    44341 ttcgttccat caccattcaa cgcatctaat agtaattttt cgtaagcttc tgggctattt
    44401 tcaaccattt ctgcactatt tctaaattcc aatttgattg gttccgtttc aaatccttgc
    44461 cctacttctt tcccattcaa ggataaagaa aatccttcag ttggctgaat atagatcgtt
    44521 agaacattag gtggaagtgt cgtatcgtca catggttcat cgacagatgt tttgaataca
    44581 ttaacaggaa cttgtttgaa tacgatgttg atccgagtcc ctttttcagt caaacgtttg
    44641 cctgtacgta catagaaagg aacacctgac caacggaagt tatcgatagt gaatttgcct
    44701 gcgacgaatg tttcagtctc tgattgagca tccactttgt cttcttcgcg atagcccttg
    44761 aattgtacac catccaattc accttgagca tattgcccgc gaacgaagtt ttctaacact
    44821 tcttcttcgt tataaatgcg gatagctttc aatgctttga tcttttctgt acggatttct
    44881 ttttcggaaa atgctactgg cggttccatt gcaagtaatg ctacaacctg taaaatatga
    44941 ttttgcacca tgtctttaag tgcgccacta tgatcgtagt agcccccgcg atcttctaca
    45001 ccgaggtttt cgccaaaagt aatttggata ttgtcgatat agcgattgtt ccattgagcc
    45061 tcaaaaatat tattggcaaa acggatagct gagatgtttt ggatcatttc ttttcctaaa
    45121 taatgatcaa tcctgaaaat atcttgttct gggaatactt ctctgatttg ctggttcaat
    45181 tcaaaagcag actggtaatc agaaccgaac ggtttttcta tgatcaaacg attgaagcca
    45241 ttttttgtca taatattttg tgatttcaaa tgagaaacga tcgttccaaa aaattgaggt
    45301 gccatagcca aataatagac acggttaccg tttaattgat agtgtccatc taatcggtca
    45361 gacaattctt ttaatgtctg ataatgcgtt gaatcattta catcatggga ttgatagtaa
    45421 aaatggcttg caaaggtagt tgcttcttca tctgaaggat tcaatgcacg gattgtttct
    45481 ttgacaactt cacggtagtg ctcatcgctc cagggacggc gagcggttcc gattacagca
    45541 aaatgctcgc ctaaatttcc ttttctgtaa aggcggaaca aagacgggta caatttacgc
    45601 tgggctaggt cacctgtacc gccgaatatc gtaaacaata catttttttc attagacatg
    45661 tggatacact cctttatatt ttatcgacaa aaatcgtgct ggccgcctta aagctgacgg
    45721 ggattttctt tctatcattt tggatagtga tcggtccttc ataagctgcg atgtcaacga
    45781 tctcatattc ttcgttgata ttcaggtcaa tagtgactaa gtaatccaac aattcttttt
    45841 catcaagcac tcgtgcgata cgcacttttg taccgacagg ataggactcc aatgtttgtc
    45901 ggcgttcttc atggacaact tcctcttttt taggaatcga tcctccatga ggacaatgtt
    45961 caggatgatt caaatagttt tctaaatgat ctgcaagatg ttccgaagtc acatgttcca
    46021 atacttcagc atcatcatgg acttcattcc agctatagtc taaatgttca actaaaaaaa
    46081 cttcccataa gcgatgtttg cgaatcagac tgctagcttt ttgcagtccg cttgcagtca
    46141 attgtacacc ttgataaggg gaatgttcta caagctcttc tttcacaagt ttagaaatca
    46201 tttcactgac agatgcagct gagacatcta gactagatac gatttgttta ttgttgactt
    46261 tcgttgtatc tccacctagt tctaaaatga ttttcaaata atcttctcga tttggtgtca
    46321 tattcgatca tcctttcatg gtaaaaaacc atcattagta agtgtaacaa aaaaaacgtt
    46381 aattgactat ttttctaaat aaaaaacaaa ggatttttag acgtttttac aacaaaaaac
    46441 gaaagatgat agagaagact cattctttcg tttataaagg atatatatat acattgggag
    46501 ggatctattt ttcagataac aacttatatg aagtgtctgc agattcgtca taaagagttt
    46561 gttcgggata agaaaagata agataaaaac catactgatc acgtacgact aaacgatatt
    46621 catctatttc taccacagat gtgccaagag actgaccgtt gatcaaaaac gtgtaatcag
    46681 atgtaatctg taattgttgt ttttgctggc tatcactaaa gaaccatgta ccttgatact
    46741 ttgagagtcc ttctgacttt tccgcttgtt ttttcttttt caagtaaata aaacttgaga
    46801 gaacggtaat gagtgaacca agaaaataga tcattttttt tatcaccaaa tcactccttt
    46861 atgagaaaat aatcgcatag acatattctt tcttctttat ttcattgtac cgaataaaag
    46921 ctaaaatttc tctaagactt tcgactggtt tttttactgt ttttctacaa attatgatag
    46981 gatacatagt aggaagaaag gtgacataat ttgaagtatc agcaagtgga aatagctttt
    47041 tttattgacc gcccgaatcg gtttatagca cattgtatga aaaaagacgg agaaataatt
    47101 attgcgcatg tcaaaaatac aggtagagga aaagaggtcc tgataccagg cgctgaagtg
    47161 gctattgtat ttgctcctgg acctaaacgg aaaaccgcct atgatctgat tgctgtaaaa
    47221 aagaagggtg actggtttaa tatcgatagt caattgccta atcggctggc aattgatggt
    47281 attttagacg gcacgatcct tttaccagga ttaactggtc catttacggt atacaagcgt
    47341 gaagtaactt atcttcactc caaatttgat atttatttag agacggtggt cggacaaaaa
    47401 gcatttgttg aagtcaaagg tatgacactt gaaaataaag cgattggtgc ttttcctgat
    47461 gcgcccacac tcagaggatt gaaacatata ggagaattaa cgtatgccgc acaagatggt
    47521 tatgccgctt atgtcttgtt tattgctcag ttcgaacatc ttcatctggc aacgatccat
    47581 gaagaaatgc aaccagcact agctgatatg gttcgacatg cgcagcaaag cggagttcaa
    47641 atcctcgcct ataattgtca agtatcggca gatgaggtaa ctgtcaagca ggccattcca
    47701 tttgatgtag atatcccttt tgaagatcct atacaataga aagaaggtaa aataatgatc
    47761 aacttaggta ttatcggaac aaattggatt actcatcaat ttgtccaagc agctttaagc
    47821 acaaaaaaat atgaattgac agcggtatat tctagacatt tggaaaaagc acaggaattt
    47881 ggttctcatt atgaagggga tatcgaattc gcaacagatt tgaagacttt tttcaatatt
    47941 actcatatgg acaccattta tattgcttct ccgaatagtc ttcactttag tcaagctaag
    48001 caagcaattt tggcaggaaa aaatgtgata gttgaaaagc cagctttttc gacgccaaaa
    48061 gaaatggatg aaatcatcca tttggcaaat gaacacaatg tgtatttttt tgaagcagca
    48121 agaaatatcc atgaatcagg ttttaaaaag attgccgatt acttaccatt aaaagacgag
    48181 ataatcggtg caaatttcag ctatatgaaa tattcttcgc gctatgacca agtattagat
    48241 ggagaagaac cgaatatctt ctcgactcat ttctcaggtg gtgcattgat ggatttaggt
    48301 gtttaccttg tatatgcagc tgttgcttgg tttggaatgc caaaagaagt ccattatttc
    48361 ccaagaaaga tttctactgg tgtagatggt cttggatggg ggatcttacg ttatgagaat
    48421 tttgatgtat cgatccagcc aggtaaaatc ggtgattctt atttaccgtc agagatttat
    48481 tttgactcag gaacgctagt gatgaatgga gtcaatgcaa ttgaacaagc acaatttcat
    48541 gatcgcgcgc ataaagaaat cattgatttg gcggtaacag ctgcagaaaa tccaatggca
    48601 gatgaagcag aggattttgc caatgtcatg gctcatccga aagatccagc ttggggattg
    48661 ttgtatgaag agtggatcga gctagctaga aatgtgaacc aagtgattta tgatttaaga
    48721 aaaaatggcg gcatcaaatt cgatgcagat aatgaggaag atttttaatg aacgaatttg
    48781 tacaagtatt tcccgaaaat tggcagaaaa aatatgagga taaagggttt atctcacctt
    48841 ctcttattca acgagcagtt tttcagccac taagtaataa acaaagtata gtagcggttt
    48901 ctcctacagg ttcaggtaaa acactggctt atctttggcc tctactacta aacgtggaac
    48961 caggtgaagc aagtgcgttg gtcatttttg cttcttctca agaactagct attcaagtag
    49021 cagatgttgc acgtgaatgg ggaaaagaca aagagttgaa agtccaatct ttggtgggcg
    49081 gagccaacgt caaacgtcag attgagggtt tgaaggaaaa accagaaatc ttgattggta
    49141 caccaggaag aatattggaa ttgatgaaag caaaaaaaat aaaagcacat caagtgaaaa
    49201 caatggtatt tgatgaagca gaccagctat ttgacgctgg gaacagccaa atcattgatc
    49261 aaattcttca tcaagctcca acagagtatc agctagcttt tttttcagcg acagcagatc
    49321 gttcccttga aagcattgaa aaaatcactg ggaaaacgtt tgagacaatt gacgtgacag
    49381 cagaggacga ttctcgaaaa ggactgagac attacttttt acgtgtaccg atacgaaaga
    49441 aagatgacta cttgagacgt ctcacgcata tagaagattt tcatggtctg attttcttta
    49501 atcaactgac tgaattaggc gtaatggaag aaaaattgct gtatagaggt gtaccggtag
    49561 gaagtctggc ctctgatcag aacaagctac tccgaaaagc agcgctagaa caattcaaaa
    49621 agaaaatggt cagagcactt ttgaccacag atgtggcggc tagaggttta gatattacag
    49681 gtcttcctta tgtagtgaat gcagaagttc cgttaagtga agaagcttat ttgcatcgtt
    49741 cgggaagaac tggtcgaatg ggtaatgaag gaatagtaat tacactcgta caagataata
    49801 atctaagaga tttaaaacgg cttttacgtc catcaaatat aacacttgaa gagatttttt
    49861 tatacggagg taagctgcaa actgagcagc caaccaaaga agatgcagct cctgcagtaa
    49921 ataaaaagta tgcgaaaact ttttctggaa aggagcagaa cccagaatat aacaaagaaa
    49981 aaataagaaa aaaagttaaa aataaatcaa aaaaagagag aaataaagga gcaaggcgca
    50041 aataagcgcc tttttatgct atgattatga aaacgggaac aaaattggtt gccagaggag
    50101 gggttatgtg aaagaacgtc aagaagagat cttgcagcta ttgacagaaa accaacaagg
    50161 attgacagca agtgatgtag ctgagcgctt aactatcgat cgaagcaatg caagccgata
    50221 tttaagtgaa ctatacaagg cccatcatat tgtaaaaacc gctggccgac cagtcgttta
    50281 ctctttgcca acggaaaagt caaaatctga tgaagtgcat gtcgactctt ctacgcaagt
    50341 gacttttgaa acactcgttg gagaaaatga ttctttaaaa gtcagcatac agcaggcaaa
    50401 agctgcgatt ctttatccac cgcgggggtt gcatacgatt atttttggag aaactggtac
    50461 agggaagtcg atgtttgctg aatgtatgta tcattttgca atcgattcag agatgctttc
    50521 tgcagatgcg ccatttgttt ctttcaattg tgcggattat gctcaaaatc cgcaactgct
    50581 ctttggacac atctttggga tcaaaaaagg ggcttacaca ggagcagctc aagatagtcc
    50641 cggtctaata gccaaagcag acggcggtat attgttttta gatgagatcc accgtttacc
    50701 gccggaaggg caggaaatgc tgtttacttt cattgataaa ggtatttacc gtccgcttgg
    50761 agaaagtgca caagtacatg aagcatctgt tcagatcatt ggggcgacga ctgaatcttc
    50821 agaaagtttc ttatctacgt tcaatcgacg gattcctatg gcaatcacct tgccgaatct
    50881 tgcttcacgt tcactggatg agcgttatga aatcatctct ctttttatca aacaagaagc
    50941 gaatcgtttg aatcaacgta tcgatatcga aaaagaagcg attcttgcct tcatgcttta
    51001 tgatgcggaa ggaaatatcg gtcaagtgaa acgagacttg aaactagtct gtgcaaaatc
    51061 ttttttacat taccgtactc atcatgagaa aaagctaatc attcgaaaag aagaactttc
    51121 ccttcaagta caaaaaggat tactgaaaat caaggaaata ccggaacgtc tcgaccgatt
    51181 catggacagc aaaagtcagt atttgacatt tgaaccagga tttgctgatg ttgtctggtc
    51241 acaagatcca gaacgaaaca tgcaggtcta taacgatatt gaggaaaaag tcacttctct
    51301 ttccgaaacc ggtgtggaga acattgatct agagaccctc atttcaaaag atgtggatgc
    51361 ttatttccag acatatgtca aagaattgac taaaagttcg attcccaaag atcttttgcc
    51421 agatgaaatc tggcggttaa ccaatcaatt gtatgatgtg gctgaaaaac ggttagaccg
    51481 tatttataat gaaaaagctc gttttgcttt tgctttgcat ctgcaaagta cattggatcg
    51541 tgtgagagaa ggtcatatga tcgtccaccc agatttgaat aacgtacgga aaaattttaa
    51601 gagggaattc caggtagcaa tcgatctttc aacgatcatt gaagaagaag aacaagttga
    51661 gattcctttt gatgaaatcg gctttattag tatgtttctt tctatcaatc taggagaaag
    51721 tgagcctgtt aaagaaaaca aagtagatgt tctcatattg atgcacggca gacagactgc
    51781 ttcaagcatg ttggagatgg cacaagaact attaggaaca aaagtaggga aagcttttaa
    51841 tatgccactg gttatggaag ttcaaacaat gtatgaagaa gtgttacaat atgtcaaaaa
    51901 ctatcaagag catttgacga atggcctact cttgttaaca gatatgggat cattaaacac
    51961 cttcagtgat ttgatttatg aagagactgg cattcggacg aaagctatca cgatgacaag
    52021 taccatgatt gtgatagaag cgatacggat ggcaagtgtt ggaagaagct tagaagatat
    52081 ttatcaaaat atccagcttt cctttgaatc gatcgtacgt gatcagttca aagcggaaaa
    52141 gtctgaaact ttacagcgta aaaaagccgt aatcgtgaca tgctttactg gtgaaggagt
    52201 agctgccaaa ttatatcagc gtattatgcc agtgattaat caaaataagg tagaactgat
    52261 ccagatgcag tttttagaac gtgaatcatt caaaaaacac atcgatgcct tattggaaga
    52321 atatgagatc aaagcaattg cgggaacagt tgatgttgat tatcaaaata tcccattttt
    52381 ttcagcctat gacgtttttg atgatgaaaa actaaatatt ttaaagcgta tagctgatga
    52441 tgagatcccg acagctaaaa ttgtcgattc acttgctgga tcattaagcg atgtcttttc
    52501 tattgatgaa ctgatccgtt cattgcaaaa gacagttcag cagatccaga ccgatttgtc
    52561 gattatcgtg gaacctggag tagatactgg aatcgttatc catttagcct tcatgttaga
    52621 cggattgatc aaacaagaaa gccatcggca atttgagaaa ctgtctattt tctcaaaaat
    52681 ttatcgtttg gaaatggata tcgttcgggc aaacttgatg gcactagaac gaaaatatca
    52741 ggtaaaaatt ccagaagatg atatcgcatt tcttacacaa atgtttcttg aaaataaaat
    52801 aaaaaaatga acacactaat catactgttt acacactaaa catctgtgtg cgcactataa
    52861 aaaagagcta aaaagcatga aaacgctatt tcagctcttt tttttattgg catgcttctt
    52921 gcgttatata aaagtgtaaa aaaataaaag gagtgttaaa aatggcaaaa aaaacaatca
    52981 tgttagtttg ttcagcaggg atgagtacga gtttattggt cacaaaaatg caaaaagcag
    53041 cagaagaaaa agggatggaa gccgatattt ttgcggtctc tgcctcagat gcagataata
    53101 atttagaatc taagaatgtc gatgtattat tattaggtcc tcaagtacgt ttcatgaaag
    53161 ctcaatttga acaaaaactt gcgcctaaag gtattccatt agatgtcatc aatatgcaag
    53221 actatggcat gatgaacgga gaaaaagttc ttgcacaagc agaaaatcta atgaaataaa
    53281 tcaagtatgc agttgggggt ataacaacgt ggaagatcaa caaaacctag aagccatcat
    53341 ggggttaatc atgtttggcg gtaatgcaaa gagcgatgca atggaagcga ttgcggctgc
    53401 taaaatcggt gattttgagt tagcggatag gaaaatcgct gatgcagaag aatcacttat
    53461 acaagcgcat catgcacaaa cagacatgtt gacacaagaa gcacaaggaa atcatatgca
    53521 agtgacatta ttgactgttc acagtcaaga tcacttaatg acatctattg cgtttactga
    53581 tttagcaaaa gaaatcatcg aactttatcg tcgcgtatac agcgaataaa tacaacttct
    53641 tttttgaacg gaagaagaaa aatttttgaa cggatttttt attttgttat aaggagaact
    53701 ctctttatat aaaaaactta taggaggaag taaaaaatga acggactatc aagttggatg
    53761 gagaaataca tcctgccggt tgccgcaaaa atcggagcgc aaaaacattt agttgctttg
    53821 cgtgatgctt ttatcggcac actgcccgca acaatggcgg gatcagtcgc tgtaatgatc
    53881 aatgcaatta ttcgtgattt accgcaacag tttaacagta cctatgctga cagtttagca
    53941 gcagacaaag gaatctttgc cgtattgaat gtcatcatcg gaatcaatgg ttttgtctgg
    54001 aacggtacac tagcaatcgc cggattgatc tttgcctttt cttgggggta taatcttgcc
    54061 cgagcttatg gagtaaatga tctagctggg gggatcgttg gtttagctac cttgattcaa
    54121 ggtatttcct ttggtccagc attatcagca gcattagatg tgaatgttcc ttcaaatgtc
    54181 gcagatgcaa tcaatagttc tgagattggt gcaacgattg cagatggcac actgtcagtt
    54241 ggattatggg gttggctaaa actagatcat ttgaatggaa acgcttattt tacagttatg
    54301 atcatgggag ctatttcagt cattattttt tgtaaattga tgcttgccaa cattacgatc
    54361 aaaatgcctg attcagtacc accagcagta tctaaagcat ttgcagccat tttaccagcg
    54421 acgatcgctt tatacgtcat tgctattatc aattatatcg taggtcgtgt agctgatggg
    54481 caactgatca ttgatttggt gcaaaaatat attgcagaac cattcctagg attatctcaa
    54541 gggttgggag cagtattgat cgtcacagta tttgttcaag tattctggtt ctttggtatt
    54601 catggaccaa atgtattggc accagtgcta gagggaatct ggggacaagc acaactaatc
    54661 aatattgata ttttccaaaa aggttataac ggaaaaactg gtacaccagc cgtgttagat
    54721 gcaatcgaag atggaaaagc ttatatgtgg gtccgcggat cgttcgatgc ttttgcatgg
    54781 tttggcggat caggcggaac gatcgtctta ctgatagcta tcttgatttt ctctaaacgt
    54841 gcagattatc taacagtagc taaattatcc attgggcctg gtatcttcaa tatcaacgaa
    54901 ccagtgatgt ttggtctgcc aatcgtattg aatgcaatca tgtttatccc attcttgatt
    54961 gctccagtag tagcaacagc aattggatgg acagctactt atcttggcct agtcgctccg
    55021 gtatcgcagc aagtcacatg ggtagtaccg ccgttcttat tgtcattctt agcaacagga
    55081 gcggattggc gggcaccgat cgtaacatta gtatgtatgg tcgtgacttt cttgatttgg
    55141 gcaccatttg tcatctctgc aaacaaaatg gaccctgccg caggcgaaca acaataagat
    55201 gaacgtgagg agcgggacgc tttaagtttc gttcctcata atgaattttc gaggaggaac
    55261 tgaaatgatt acaattgcca gtgcaatgca acaagatgaa atcaaagaat tgttagaagg
    55321 atacaatgaa gaaggaatga cttttacatt taaagaaaaa caaggaatca agctgttctt
    55381 tgaaacaagt gcagaagatc cggaagttgc ggctaaaaaa gcaaaggaac taatcaaagc
    55441 acagccttgg ggaacagtcc tttattttca atcaacagct gtttagaaaa tggtttaaaa
    55501 agataggatg gttgagatga taaaaaacgg tttattttta tgtagtattg gttctttgat
    55561 cgtgttgtat agtttgaatc cacattcgca aaggtatgat ttgtatagta tggtcacagg
    55621 tctttttcta acaggattag gaatctattt cttcatgaag gggaaaaaaa gagaagaagc
    55681 aaaggagaaa aataactaat ggaaatcacg aaaaaattaa atattccagc atcgtttttt
    55741 tacgataaag ttatggactc tgtccttttc gatgtacgta aagcgaccgg caaatcagta
    55801 actagaaaac agctgaaaaa tttggagtac gtcaaacaat tctcgcaaaa taaccgggct
    55861 cgcataaaaa tcgaagaagt cattgaaaac cagtcttata agtttcgtac atcgacaacg
    55921 aagaatgaat tcgtcgttca ttatcaaatc aaaccattgg acgattcgac ctgtgaggtt
    55981 cattacacag aaaaaatgga gtcttatggc atgcttcaaa agttgaatga tatgctttta
    56041 ggaacaatct tgatgtattt taaacggaga cgtttcaaaa aaatgctaga tatgatcgaa
    56101 gcaacgtatt aaatcaatga aacatggtac tatttagtta ttgaaaaatg aagtaagcta
    56161 gaaggaattt ttcataggaa gatagatctt tcctgcgaat cctcactagc ttttttgtag
    56221 gaaggggcag caaaatgaca aacaaagtaa gagagctagg tgtatcttcg attgaggaaa
    56281 tgtttgattt agccacttat gcatttaatg gggcagatac acctgaaagg cgagaacgtt
    56341 ttcgtacact tgcggagaat tcttggaatt acggattttt tgatgaggag gatcggctaa
    56401 caagtcaagt catggcgacc ccttttccag tgaattttta cggacaagag tacctaatgg
    56461 ccggcattgg ctatgttgct tcttatccag aagcaagggg acaaggcggg atcaatcaga
    56521 tcatggaaaa gatccttgaa gattgccgtg atcgtaaagt aagcttatct tatctggcgc
    56581 cattctccta tcccttctat cggcgctatg gctatgaaca atcatttgat aaaatcagtt
    56641 atcaactaaa cagtcgtgat gtgccgttta tcaaaaaaaa atctggaaaa ataaagcgta
    56701 tggattttga agatgcaaaa gctgcaatca gaagaattta tgaacagatg ccggaaaacc
    56761 aacgagctgg tctgaagcgc gaagactggt ggtatacgta taaattcaag caaaaaggca
    56821 attaccagtt tgctttgcat tttgatgata atgaggaagc aacgggatat atcgtttatc
    56881 agcttgcaac gtcttccttt attattgcgg agtggggatt tttggatcat gatgcttttt
    56941 gcagccttgt tcgcttcgta agttctcaca atggtgcttt tgaaacattt gaatattcat
    57001 gcggctacgg cggtaatgat caaaattatc tattagaaaa tccatttgct tctgtaatga
    57061 tcacacctta tatgatggcg aggatcgtag atatttcttt gtttttggaa aattatccat
    57121 ttaaaaagag acaagctgca tttgccctac aaatagaaga agatcattat gcgaaatgga
    57181 atgaaggaat cgtggaagta acaatcgaaa atggaaaaaa tcatctctca aaagtagaac
    57241 aaacaaaact cccaatcgtt cgaggaagta tccaacatat cacgcagcta ttattagggt
    57301 atcgtaaagt ggaagagttg gtattccaag aaagaataca ggtgacaaaa gaatatgaag
    57361 aaacgttaag ctcaatcttg ccacagcaac agccaattct taatgactat ttttgataaa
    57421 aaacgggtga tgacaatatt tttgtcacca cccttttgtt tttcatttgg catttgaagg
    57481 aaaatgttaa agtaaatcct cttttttcgt aaatttgaat tttttgtttt cttttgtttt
    57541 agggttttct tttttgtggt cttggattgc ttctttcgta atcttttccc gatttttttt
    57601 agatgaatct aagcgttctg cgtatacttt ttcttttggc ttatcattca ttggaaagga
    57661 cctccctaca ttatttcatt ctacctctag tttatcatct gttaaggact agtggaaacg
    57721 ttttgcctaa cttataagct gattttttta gcagataagc ttgcaagtaa aaaacaaaca
    57781 agctacaatt gatttattga aattgttcct gtagctcagt aggatagagc aatcgcctcc
    57841 taagcgatag gtcgctggtt caattccagt caggaacgta taaataaccc ctgtatcctt
    57901 tgcggtacag gggtttgttt tgtatttgtg ccaaaaatgt gccaaactag ttatcatttt
    57961 tatataaact atcgaacaca gtattgattt tttctttatc ctgatcttca agctctcgaa
    58021 caatatgaag ataagtagac attgtagttt ctaaactgct atgtcctaaa cgtttcgata
    58081 cgctaagtat atttactcct tgataaagta aaatagatgc atgtgtatgc cttagtccat
    58141 gcaaagtaaa ttgcttttca atccctaatt cttttaattt tttgcgcaaa tatttgctga
    58201 cggcgtttga tgaaactaat ccatttttta agttgaaaaa aacaaaatta tgagggtttt
    58261 tgatttcaaa attctcgaat aattcttttt gattgatttt aaactttttt aagagatcaa
    58321 tcgtatgttt atcaatggaa attttcctat ttgaagtttc gttttttgtt tttccccatt
    58381 catttaattt ataattccat gttttattaa tagtgatgat ttgatcttcg aaatcgatat
    58441 cttcccatgt taatcctaga agttcagcaa atcgcattcc agtggcacca gcaactaaca
    58501 cgagcatagg agaagagtac tgcgcagaaa ggttttcttc tacgagtttc attaaagatt
    58561 taaattgatc ataatctaaa tatttatctt cttttggctt caatgaatct tttcctttga
    58621 ttactgcttt tctagttgga tcaaacggaa ttaatccttc ttctacggca tctttcaacg
    58681 acgctctaat atggttatta aacttaataa cggtagattt tacatggtct ttagcatact
    58741 tatttaaaaa gcgttgatat cccactctat ctaaatcaga aatcaatacc gctggcatat
    58801 atttctttat gttcattaac gtatcttcgt attttctata agtgatagga gatactgttc
    58861 cttctttata aagttgcatc caatcctcaa agtaatctga taataataga tttttgcgat
    58921 cccctttaag gcctttgttc aagttatatt ctaattcgtt ggcggcatct tttgcttctc
    58981 cttttgtctt aaatcctgat tttcttatct tcgtgtattt tccgtcatct tttttgtatg
    59041 aaatttcgta ttgccaacta tttccacgtt tgactaatct tgccataatt gaatcagctc
    59101 tctttctctg atacaatagg aactataaag aagcccattg tttgggtttt attatttttt
    59161 gcacatcctt tttgcttgcc ggcgcaagga tgtgctattt gtcgttttaa tggtataatt
    59221 ggatgtgtat tagatcatcc aatcagaggt gtttattatg attaaagtga tttttaaaag
    59281 aataactgaa cttccagagt ttagattatt tgttgattat tggtatgtct ggttttttat
    59341 tgttgcattg ctgataggtc tagatgtcat attagaaaga aaacttaagt aagagttgag
    59401 ttaataaatt gaattcctaa atgagatatt ttgtagccca tattttgttt gccgacatca
    59461 cctaatacta tggagctaat cgttttttct aacagaccaa aatcagataa tctatttaag
    59521 ctaccatcta ttagctcttg tgaatagcca gacatgctga tatttccagt gaaattttcg
    59581 tttccacgac tcattaagca tgctaacaat tgaatctcaa tcgatgttaa ttgattcagt
    59641 acaagaagat aatactcctc gttatcccat gaagcgttgt taattcgaag taaacaattc
    59701 ttataaagat ttttatacat atctatttta ttttgtgcct ttgatttttc tacctcgtca
    59761 tttatccctt cgaatattcc aatgagttgg tccttgttct ctaagttgaa aacatcttct
    59821 ggaatttgat cgcgaatgtt ttctaatgat tcgtttaaat ttttgtagaa tttctcgatg
    59881 cgtttgaaac gcttctcgtt tttagaccca aaaataaagt gactgcacaa cgccaccaat
    59941 ataaggaatt gctccaatac cgccttcaac tattaattca agatattctt ttttggttag
    60001 tttttcattg ctattatcca tagttacctc ctattttgtc atttccttta caagcattgt
    60061 gactcctgat ggcactcttt tgtataggtt ttattattgt gcacaatcta actcttagtg
    60121 gggcgtggtt catttatttt ttacttactt tactattaat catatcccat tgagcatagg
    60181 atttttctat gttcgatcct cttgaactaa tttctcctgt aaaagttact ttatcgccct
    60241 ttgtaaaggt atcagcattg tttaagtcct tcgcaaaaat tacatatgaa actttaggtg
    60301 ttgcagaaat atcattccaa cttttatcat cgtactcttt gtctgctata atggctattc
    60361 tagtagtcat tgattcgata acagttcctt caaaagtata tgttttacca ctaatatatt
    60421 tagtaaaagc tgtattttgc tcagtagctg gagtaataga ataataacta tctaagaaag
    60481 caccccagtc atgattattt gtctctaaaa attcttcaaa ttgagttagg cttttattgc
    60541 tgctgttaga tgtagtagtt tgagtatcag atgatgagct ttcctgtttg ttattgtcat
    60601 ttgcctcgtt tgatgaggaa agcgagaaac ctacggtagt aaaaataatc ccgataataa
    60661 ggagaatcat aggtgttttc ttatttgttt ttttgataaa tcttacaatt aacatgatta
    60721 aacctataat aaataaaaca ataccagtaa aaccaaatat accgtccatt aatagatcct
    60781 ctttctcttt tgatattgaa tattataaac caagcaattc ttttttctta aaatcgaatt
    60841 cttcttgatt aataatccct tcatctaaca actctttata ctttttaatt tcatctgcac
    60901 ttgaaatttg tgtttctttg gaattattat ctaatataga ttgttgcttc tctatatatt
    60961 tttttaaatt ttccatttca ttccaatatt tttttgtaaa cataacggtg ttttcatctt
    61021 tcgtggccgc taatatacct ccgcgacttt cgtttccgcc tagcaaggta aattgtatat
    61081 aaccattact catacctggt ttttttaatt gtacggctga tatattttta aaggggatag
    61141 ttttttctcc tttaatacct tgattaacta aatttataaa tccttttcta ataattgaaa
    61201 tagaatcatc agttacttta atcaaggttt ttcctggaga ttttattaaa atctcttttt
    61261 ccattttttc ttcctcattt ctgtgatatg attttttttg tagaagctca tatatgagga
    61321 aagagcccgt gttgcagcac gggctttttt aatgttttgc tgaaatcggt ttttttaata
    61381 attcttgatg tattcataca tattgccttg cgtaagaata ttttttctta aaatagcatt
    61441 ggcagacagc ataacaagtg tatctgagct tattctgaat agaataatac tccataaatt
    61501 tttcgagatt aaactgagat ttatcagtca gttcgttctc aatatagata tttaataaaa
    61561 ttagaatagc tattttatct gcttctgttt caaattttga gtgaaaagtt gtagaagtat
    61621 cgtacaaaac tgaaaattca aaatgagagg cgctgaaatg tgcaagttca tgagataaat
    61681 gaaaggcttc tgcagtttca ccgtatagat tttcattcaa aaaaatgatt ctgggttttg
    61741 gatagtagaa accaggctct ttcatctcca tataaactac tttcaaattg tattcgctca
    61801 acatttcttt caatttcaaa tacatacaaa ccatcactcc aactattcat tttcctctaa
    61861 agctttagca attgcaatcg ctttacgcat tgtctcctta gatatttctt ttccatcaaa
    61921 agaaaaaaca gtatcgtctt ctgataaatc cacatgttta ggggtttctc tttcttctct
    61981 acctagaagg tagtctacag agacatcgaa atagtcagca atccgactta attcatctga
    62041 attaggagta ttatttttcc actttgctag ataaccgtta gaatatccaa aattaatttc
    62101 taactgccgt atagatatct ttttcctctt cgccaagtct tttattattt cataggtatt
    62161 catcgataaa acaacctttc taaatgttta caaaaaaagt ttagaaaaat acgcagaaat
    62221 aatttgacta attctgagta atgagctata ctatatcttg taaacagatt taacaactaa
    62281 aaagacaaca aaaaacacta ttgatatgta aatgcagacc gccaagaaag ctttaaaatc
    62341 aatgttttta tgtcttattt aattatgctc ttagtataga gtattactca gatactgtca
    62401 attgaattta gaaaaaagtt gttaaatttg tttacgaata taaaagaaag gaatgagaaa
    62461 tatgaacaca ccgcaaattt ttaatttcga acaaaacgaa gttcggacaa ttttagtaaa
    62521 tgatgaacca tattttgtag gcaaagacgt tgcgagtgtt ttgggttatt caaacactaa
    62581 agatgctttg tcgcggcatg tagatttgga agataagatg gggtcgcgaa tcacgacctc
    62641 aggtcaatca agagagatga caatcatcaa cgaatctggt ttgtacagtt taatcttaaa
    62701 atcaaaactt ccctctgcca aaaaatttaa acgttgggta acaagtgaag tgttgccagc
    62761 aattagaaaa catggaggtt atctaactcc agaaaaagta gaagaagctt tgcttaatcc
    62821 agatacaatc attcaattag caactcaact aaaagaagaa agaactggaa gattaatcgc
    62881 agaacaaaag attgcagagt acgaacctaa aatctcctat ttagatagca tattatcttc
    62941 tacagattca gtaacaatta gtcagattgc agcagattat gggatgtctc cacaacagat
    63001 gaataaatta cttcataaac taggtattca gaaaaaagtc ggtaaccaat ggttattgtg
    63061 caaaaaacac atgaaccaag gatacacaaa atctcataca actgagatcc cgaaagccga
    63121 tggtggcact aaaattgtaa tgaataccaa atggacacag aaagggcgtc tatttatcta
    63181 cgaattacta aaaaaagaag gatattaccc tcaaatggat ttagaggaaa ttggttagaa
    63241 aggagtttta gtatgactga cattgcagaa atcactcaac gagatagaga aaaaatcaaa
    63301 gaatatgtcg aaagttcaaa gttcttaact tacaccatgc ttgctgaaag atttggaatt
    63361 agcaaaagct acttatcttt aattttaaac ggtaaaaaga cttctgcaga agcaaacaga
    63421 attatagatt cgattatcac tatgtacgaa ttgtaaaggg aggaacagct aatgcaatat
    63481 ctagaagcaa aaatcccaat tccagaaggc tatgtaatta tctcccaagt ggattatgag
    63541 gagttaaaaa aagctgatga tactggtaga tggatgacgt tgccagaagt gctagaacgg
    63601 attaacagaa aatatgattg gtttacttct agagttttaa agaacccaag atatagaaat
    63661 attatcgata tcgagaaaaa caaaaatgga tttgtctatt atccagttga aggaagagac
    63721 acatatctat ttttaagaag taaaacactt gaatttttag aaacaaattt ttcggaaatc
    63781 ttaaggaggc aagcggatgg gaaaatttaa tagagcgcta gtgttcagcg caccgctaat
    63841 catctacgct ttaggacttt ggggaagcag gcaagcgttg ataggaacga ttgtttacat
    63901 ggtttggatt tttatggggc ttgatgaagc tgaagctgag tacagagcga aaaagccaac
    63961 cgagggggct gactaaaaat gaatagaaaa gagaaactag aatgtatatt actattactc
    64021 agtttaattc tttcactaat ttctctattg ggaagtttgt atttttgata tcaacaattt
    64081 tgtggatttg ggttctattt agagtaaata tcatttttgt ttggtgatta aggagtttat
    64141 taaaattaat tttccctact tcaaatgcaa ggtaacaaga tatagcactt ttaggaggaa
    64201 tatttagcgg tacagcttca gagtatattc tattatcatc gactgatcct cctttagcaa
    64261 ttaatttctt aaatggagta gctgaccatc tgcggtttaa gttagcggat gaaagttcta
    64321 aattaactaa catagctggt tctgttgaat agttagaaat gattactttt gtataaatca
    64381 tatctgcagc gaagtaagaa gcattaagtt caacttctag ttgagggcgc attcctttta
    64441 tttttatccc tgttaaaaac gtactcaata taaaacttat tattgacatc cattgaaaaa
    64501 ttgttaagtg aaaaaaattc aaaataaaca ccaccagttt ttaactaaat tataccaaaa
    64561 aggagagaag aaataatgca agaattagta attttgaaaa ataaagaagc tgtgactacg
    64621 agcttacaag tggcagaaag cttcgagaaa aaacatcaac atgttttaag agatattgat
    64681 gcactaaaaa aagatgtgtc caattttgga cagatgtttg tagaaggtaa tgaaccagat
    64741 tcatatggca gaaatcgacg agttttcttc attagtagag atggattttt cttgctggct
    64801 atggggttta caggaaagaa agctatctac ttcaaacaaa aatacattga agcattcaac
    64861 gaaatggaag atgttattcg caagaatact gttcctcaaa caattgaaga tatgatgatc
    64921 tatcaattag aagaaatgaa agatgttaaa aaagatgttt ccatgcttaa agatactatg
    64981 cgaattagcg gacaacaaga gtttgaaatt aagcaaaaag gaaatatgaa agttatggga
    65041 gttctagggg gaaaagaaag ccgagcttat gaagaaatca gcaaaaaagt attctcaaaa
    65101 ttttggtctg aatttaaacg taccttttca atcccaagat atggcgagtt acctcgtaag
    65161 agattcgatg atgctgtttc atttattgaa atgtggttgc cagaaactgc gatccgtatg
    65221 gaaattgatc aactgaacag acaacagaga ctttttggtg atgacaatga atagagctga
    65281 agcgctaaga atagggacgg caattgctaa ttgctggtgg aaatactata aaccaatcat
    65341 cctaagccaa caacatattg acaagcaaaa agcatggcaa caaataaaaa agtgactccg
    65401 ccggcaagca aagagtcaca aagaaaacac atcataagga gattttagca tatggaaaaa
    65461 gaactttcca ctctagatca atatttgatt gatcctgatt ggggcaagcc gaaaattgag
    65521 gaaacaagtg gtcgaaaaat cagacgaaat cttttgacga atgaagaact agcttgggat
    65581 caagatgatt taggcaacca tgtaactatt tgggatcatg tttatcttat ccatctatcg
    65641 aagcattcga ataaacctga atatatttac gtcatcgaag atggcttgat tgatgcgcta
    65701 gaagagtacg acagagataa cttgattgat atctcttatt acggaccagg taagaaatac
    65761 attgctgaaa tggaggcaga atttgatgag tgaaatcaaa gggacaacga actttgaaaa
    65821 actttttagt cgtaagttaa ataaaattct caagaaaaaa ggaaattttg attatttatc
    65881 ttgggctcac gcgtgggaga ttatgaaaaa gaatgatcca caggcaacgg taactattaa
    65941 tgagtacaaa cactacaggg ttgtttctgg aactcatcaa gactttcttg ttgaggaata
    66001 taaacctttt cttatggatg aaactgggac ttatgtatct gtctcagtaa cggttaaagg
    66061 acacacggaa accgaattat ttcctgtttt agattatcga aaccaaccag ttgttaaacc
    66121 aaatgcaatg caaatcaata actcattgaa gcgatgcttt gtgaaagcat tggctctaca
    66181 cggactggga ttatatgtat ttcaagggga agatattcca acaccaccta gaatcgatac
    66241 aaagaaatta aacatgctag agacgattct agaagctttc aatgagcaga tgggtaaaga
    66301 tatgaccaaa accttaatcg aatatgttaa tgagcagaca gataaattag ggctcttagc
    66361 tgataacgtt gaaactattg aacagttaag ctatgagcaa tgtgccttga tggagcgagc
    66421 aatagcagct aagagaaaag aattagataa gaagtgatat gagtgtttaa accattaatc
    66481 gattcatatt cagcggttct gaaaaagttc aaaggaaaag acataagcgc aaccatcaat
    66541 gaggaagtga acattgatcg actaaagacg atgtatgacg gctacgatgg tgatcgagtc
    66601 attgaaattc gttttattga tcctagacgt ttcaccgtac agcaacgaaa cttcatctat
    66661 gcgctgatag gcgatatttt tatcgataca ggcatgccaa cggacttctg gaaggaattc
    66721 ttctactttc gttttgaagg tgtcacaggg cgcaaaataa gcctgaaaga cgaatcgaat
    66781 acaactgtga gtgatgccaa tgtcttagca aatatcatct tagatttcat ctttgaacat
    66841 catattcctt tcaaagaagg ctatgagatt ttacctgcga atcaagaata ttacttctac
    66901 aaatgcatca caaaaagagt ctgctgcatc tgtggcaaaa caggagctga catcgatcac
    66961 tttgacaaag cgctaggaag acgaaagcgc aaagaagttg atcatgcaga gtacacattt
    67021 gcagcactct gcagaatcca tcacacagag aagcacaaaa taggtgtgat taatttcaaa
    67081 aataaatatc aaatcaaagg gatcaaatta aaccagaaaa caatcaaaaa gttaaatatt
    67141 ggagggtaaa aatgacagaa catcgaagtt attatgcgat tataccagcc aacgtaaggt
    67201 acgacaaaag acttaaacca aatactaagt tgttatacgg agagataacg gccttgtgta
    67261 atgaaagagg cttttgttgg gcaggcaatg agtactttgc agatttatat ggtgtgaata
    67321 aagagaccat atcgcgatgg gtaagtgatt tgattaagtt tggatacttg aatcgggaaa
    67381 tcatttacaa agagggtacc aatcaaataa tcaataggta cctacgaatt aatcaatacc
    67441 ctattgacga aaaacgcaat acccctattg acgaaaaagt caaagataat aatacatcta
    67501 ttaataatac atttaataat acaaaagaat atataagaga gttaccgcct tcgaaaaaat
    67561 cgaaggctaa gcccgtccgt cataaatacg gagagtataa aaatgttctt ttgtcagatg
    67621 agcagatgga gaaactcaaa acagaattcc ctaatgatta ccaagagcga atcgaacgac
    67681 tgtcagagta ttgtgaatca tctggtaaga cttataaaaa ctatttggca actattcgaa
    67741 gttgggcaag gaaagaaaaa agtgaaccta agaacgcaag cagtggatac aagcgcacag
    67801 gaagacgaga gaagcttcct gaatgggcaa tcgaccaaga agcctatctc aagaaaaaag
    67861 cgctagaacg agctaataga caatcaaaag caccattcta agaggtggaa aaatgaagat
    67921 cgattatcta gaactaatta atgaaatagc gaattataaa aagggcgagg aattagacgt
    67981 cctgagagac gtatatgatc aactcgaaga agctggaatt gaaggaatta agaatgatcg
    68041 ttcgagttgg agtaagctca gatactattt cgcactttat atcgatacaa cacaattaag
    68101 aaatttagca tataccaaat tactatttgt tgattgtgtt aaaggcttgc aaaaacatct
    68161 taatgaactt gagcaggtgt aatcagatgg acctaaagac atttacagca cagattgaac
    68221 taatgcatca agaagcttta agacaaagtg tatcgtacga agacaagtgg ctcaacacgt
    68281 tccatggcgg acgtgagagc gcacttgatc aagtactcaa attactgaaa ggagaatgtc
    68341 gggatggata agaaagcggc aatgcagcga attatcgaat tgacttattc agaagattgg
    68401 caaaatgaca aagaagctgc ttcagaagtg atgaggcttg gaagagcgat gtgggcagac
    68461 aagagcaaca agccaagacc acgaaaaatc gcaatttggc acggtgacaa acttctagtg
    68521 atagggacag ctgaacagtt agcaagtctc acaggcttgc acgagaaaat cgtgaggaaa
    68581 agagcaaggt gtggctacac agacgctaag aagagaacgt ttagatacgt ggaggaatca
    68641 tcatgacaac agaagaagtg attcaaatgc gtattcgaag ccttcagcgt gagattgacg
    68701 atctggaacg aacaaaggca gtgatggtca atgaaacggc gagaaaggca atcgatttgc
    68761 acatagagaa tttaagaagg gaaatccatc gattggagga atgagcgtgg ataagaaagc
    68821 agcaatgaaa agaattgctg aattaaccaa gtcagaatct tggcaagaag acaaagaaat
    68881 agttgcagaa gtccaaaagc tcggtaaatc aatgtggact gaaaagccca aacggagaac
    68941 gccgagaaaa attgcaatct ggcatgatga ccgaatttta gtaacaggta ctgctgaaca
    69001 gttatctgaa attactggat taagcaaaaa cattatctgg gatagagcta ggagcttatg
    69061 gattgattca aaaggacgac agtttaggta tgtggaggag agataatgga tctcattaca
    69121 caatacagtg acatcatcct caagaaaatc atgatgaaga ttcagaaaga taaaaaatca
    69181 aaagaacgag ctgaattagt taagttagaa atggctgaaa caggagcagg agtgcgaagt
    69241 agcaggcatt ggaaagcagc agcaaacatt gaattttatt acaacgaaat tcaaaaaggg
    69301 ttcgatcaga tgcgtgagct ggatcggcaa acaaattgga gcaagaaact tcatcaagat
    69361 cgtttcaaat ttgtagagaa gtataaagaa atattagaag agtatttgag gaggacagca
    69421 aatgataaaa aaactcgttc aattcagcat ggatttatat gatatcgaat caggagcaac
    69481 actatctgtg gaatcggacc atctaatcat aaattttggt ggaaagcgcc agattatttt
    69541 gtgggtagtt gatgatgtac tgtttccaga aattgttcat gatttcgaag aatcaaaagc
    69601 ggttgagttt gaaatagtga aaaaagtaat ggaattgatt gaaaaatacg aggaggacag
    69661 cgaatgatac cgaagtttag agcgtgggat aaacgaaaga acgtaatgag agatgtagcc
    69721 gtcttgcatt ttactaaaaa cggcaaaaca aactttattg aatattggat aaatcctacc
    69781 gaattgaaat catatcacgt gcgaaacatc gacctcatgc aatccacagg aatgaaagat
    69841 aagaatggtg tggatatatt tgaaggggat atagtattag tcagcgtgcg aaatggcttc
    69901 gattacttag ataataaagt ctgtattgtc aaaaattcaa tagattattc cggattagtt
    69961 tgtgccactg ttgatgaaga cttagagtat caaattttta acacagagct gtttgaagaa
    70021 tacacgtacg aagtcaccgg aaatatatac gagaatagcg agttattgga ggaacagcga
    70081 tgaataaaca ggaagcaatc aaaaagttag aaagtattaa agcgatagga aatgatgcaa
    70141 tagctgcttg ctataacgag agtataaatt caggtattac gttaatgaaa aaaatagacg
    70201 aaccgcagaa accagttatt ccacaactcg tggccggttg gcttgagaaa tctacggacc
    70261 cttttacaaa agctgaaaaa atagcgtatt taatcaaatc taaagatggt gattcatatt
    70321 atttctgtga ttggtttgta cgagatggca tagtgacgca agagcaagga gaagaattac
    70381 tcgcttgggc aacaagacaa tcatatgaaa cactattgag cctatacaac ggctacgagg
    70441 ttgagaaaga gccgttatgg gcaataaaga atgccgatgg aaactatctt actaaatgtg
    70501 ctttatgggg aaaagatgga gtaaattata gttttgaatg caatccatct catcgattgc
    70561 ttttcactga taaagcaaca gcggatgctg cagcattgtt ggtgaatgga acagtggaag
    70621 aggtggtaga aagatgaaac taaaagacgg attttacgct agcagtcacg gtatcggcgg
    70681 tttaatgcta gatatgccga caaagaaccc taaaacacgc aagaaatcaa aattcaaagt
    70741 cggtgacatg gtccgctgtg aagcagaaga gttcgtttat ccgttcagag gatacgttaa
    70801 aaagatactg tcaaactcag caatcattcg tattgaaaat acaatgaagt gtgatcgttc
    70861 gactgcaaaa cacaagcatt atttagctgt agcgagatta gttgacatgg aagtaatcaa
    70921 gagcaaataa aaaaagccgg atcgctccga ctgattcaat aaatccaaca catttattat
    70981 atcacataaa ggagcggttt gacttgatgc aattgttacg agaggtagat ttcaaacaga
    71041 caagatgtaa tgcgagagat gtgctgaaga actttcggcg tttggagcgg atggcaggtc
    71101 gctctttgat agatattaag tcgccgatta taacggatat gccgaaggca ccgaagcatg
    71161 gcaataaggc agaagacgcg attattcaga tgatggatat agaaacggag agagatgcga
    71221 ttctagcggc tttgatggct cttagtctga ttagtcgtca gatactctac tacagcttct
    71281 gtgtgccaga tagcttctca aactacagaa ttagccgtga agtgggttat tcagaaagaa
    71341 gtatacaacg gatgaagtcg gaagctctaa tagagtttgc agaagcatat aaacacggaa
    71401 aaataattgc ttataaataa tttggcggtt ttttggcgga atgatggcgg tttttagaca
    71461 tttaccagtg ttattatggt agtgtcgaaa gattaggaaa caggatcgac aaaataaacg
    71521 aagggaggca atctccctca tcgttttaaa cttcttctta gatagacagc aactaattat
    71581 gaagaaaagg atgtgaattc aactcctcct aaattcttca tcggttgctg tttattttga
    71641 ttagacagca gcactcacaa aactaaacat gttcttgtcg tctttcaact gctgctgtct
    71701 attaatttat gtattggagg gaagaaaaat gaaattatca gtagaaggca ctccagaaga
    71761 aatacaagaa ttgctccaag ctattggtag tagcaaggag caaaaggtaa gtgtttctaa
    71821 ttcagatatt gacggtattt gcaattgttt aaacagagaa aaaatatcta atccttacta
    71881 agagaaaata tgttcgttaa tgaatttcca attttcctct gtagctctac cttgataatt
    71941 tttttgcagt tcacagatga ataaggaatc gttattatca agtactgtat ttaatttttc
    72001 acacatttga tttggattca aattagtttt aactaaccaa aaagattttt gtagctttat
    72061 atatgcccca aattctttta ttatttcaaa tactttatca tacttttgcc ctgggttatt
    72121 aagatcataa ctaatcatgt agggtttata catgttgtct tgcacatcct tgttttatat
    72181 ttcagcggac cactcgctga taaataaaat tatacgctta gtatttattt tcacaatatt
    72241 aatttatcgt aataactttt gagtaaatag aacaaaaaac ctgcactagt ttccgctagt
    72301 acaggcagtg actatatcgg ttgataatct agcatatatt aaaaataatt gcaagaaaag
    72361 aaatttatag tggtttatac caaattatca aagcaatgtt attttgttgc tgtctattgt
    72421 tttttaatta ttcacacgat aactaaaggt gggtgaagag aaatgattcc attaataatt
    72481 tcaatttttg cgctctgtct taatgtctat atgattggat ttaaaaatgg gcaaaataaa
    72541 aaatagtagc agccaagaat aattttatag tgtcactgtg gcggaaaggg tagacgctaa
    72601 gcatgtgtgc taggtcaatg cttcggcaac catgcaaggt tcgattcctt gccagcgaca
    72661 ttaaatgcct atgacggtta cgactaccga aaaaagatcg ttaagaagct atacggtgct
    72721 acgtacggca atgtagtaag tgtgctatct gtacaccacc aagcttcggt cactgtggcg
    72781 gaagtagaag acgcagcggt aaatggcgag tagcctcgtg agagcctggt aagttctcgt
    72841 gagtggtgca atcccactcc agcgacttta agcaaccgag gcatcggcgg tttaaaaata
    72901 taggggtgcg caatttcgta cgcgttttgt gcatcgtgca agttactatt acatattaga
    72961 tcactctttg agtggtcttt ttatttttgc acaaaggagg aaacaacaat gtatagacca
    73021 caatacttag aacagaagta tgaagtaatc actgttcata aaggtaatgg cgaaaaagta
    73081 tatgagtata gaagaccaat aaagagcgat acatataaac gaaaggaaaa caatgaagtt
    73141 attccattgt atggcaaaag aatagctaag cattaaataa gattgcgaaa ggagacggaa
    73201 catgaccgag gaattctata gatggctatt acagttgaca agagaagatc gtttggttaa
    73261 gttctatcag tctcctaaat ggcgcaggct tagagagaaa gcgatgaaac gagatcacta
    73321 tgaatgccaa gagtgtagaa gactaggtaa gtatcataga gtagagaacg ttcatcatat
    73381 aaaggaagtc aaggatagac ctgacttagc tttagattta gataatctta tttgtttatg
    73441 tgttgaacat cataatgaag ttcatggcag atatcttaca gcattagata aacaagagaa
    73501 gaagatagaa agctttgcta acttcgatgc aagtgaaagg tggtaagtgc atgatcatca
    73561 atgataatgg cagagagtat gatacagaaa agattgaaga gtattcatct tatactcagg
    73621 gattaattaa acgtttgata tacgttcgct atgtaggtat tagggatctg ttatcagata
    73681 actgttgtag taaatacaaa gtgaatcaag taagagaagc gttgaataaa gataataacg
    73741 tcgaaagaat aaaaaatgtt tttggatata gtattgaaga gattaattat tacattgact
    73801 tcgctgaagc tttcattccg atggtgagat aaccccccct taaaataaat cgcaaatttt
    73861 ttgggggtga tgaaacggag ggggctgtca ggaaaagaga ttttttcgaa ctttatcatg
    73921 aaaggagggc taaaatgttt aaaaacgaat tgtctcaaaa tcgctacaga gaaaaattac
    73981 gccgctcttt aataagccaa ttggaaagtc agaaaacaaa tattgagcca ttcttagata
    74041 atgttgatcg ttatatcagt ttatgggaaa cggcgatatc actggaagaa gatatatccg
    74101 agaacggcat tagactggag aatggtaaaa agaatgaatc agtagcgttg cttgtttctg
    74161 tcaacaaaca aatgggattg atgttggata aacttgccat tactcctgaa ttggtaggtg
    74221 aagcaaatga atcaattcct gagttataag catattgaaa attggttcaa agctatagaa
    74281 gaaggcacta tcaaggtatg caaagagcaa ttattgctaa aaaattatct agaagaaaga
    74341 gtctttacta gagaagatat ttacttcgat aagcagatgg tagaggattc aatcaatata
    74401 ccagcacaat actttccatt cgaattaatt ccgtgggaaa aatttctaca atgttttatt
    74461 tatggtgttc gatggaaaaa agataaaaca ctagtgttca atagatatct ttcattaatg
    74521 ggacgtggta atggtaaaac tggttttgct tcttggaaca acttctttct actaaccgct
    74581 aaacacggta ttaaaaatta tgatattgat atctatgcca ataatgaaag ccaagcaaag
    74641 actagttttg atgatgtatt taaagtaatt aaagatcatc ctgatttaga taaaaaagta
    74701 tttaaagcta cgaaggaagt tattcaaaat atcgctacaa acagcaaact tcgttataac
    74761 acggcaaatg ctagaacaaa agatgggaag cgaccaggtg caaaccgctt tgatgaaatt
    74821 cacgaaaatg aagattattc aatgataaat gtggctactt ctggtggtgg taaaattcga
    74881 gattatagag aattttatga tacaactaat ggtcatgttc gtggtggtcc gcttgatgac
    74941 attatagaag aatcaaaaat gattctttct ggagaacttg gaattgacaa ggatggagca
    75001 gaattttcta gtttgtttcc atttatttgt cgcttggata acgataatga agttgatgat
    75061 cccgacatgt gggaaaaagc ttgtccaact attaattaca atgcagattt aaaacggaaa
    75121 atgtttcaag aatactctca aatgcaacgt aatgctggtt taagacttac gttcatgacc
    75181 aaacgaatga acagacctat ggaagataca cgatttgctg ttgcttcata tgatgatgtt
    75241 ctgcatacga aagaaaaaga atttcctgaa aaaatggatg aagtgatagg aacagtcgat
    75301 tttgctgata gacgagattt tgccagcgtt gggttgctag gaaaatacga taaagatgtt
    75361 tattttacac aacatacttt tatccacgaa tcagcccttc gattacaaaa catcaaacga
    75421 gaggttatag atatttctat agatcaagga aaatcacaga tcgttcatgg aaaaaatata
    75481 gaagctgatt atattgtagg ttggtttctt gaaatgagta ataaatatta tattaaaaaa
    75541 atcgctatgg atatgtaccg tgcaaaaata ttgaagcccg ctttagaaga agcaggtttt
    75601 actgtggaaa ttgttcgaag cggatctgtt acacatggta tgttaaaaga tctggttgat
    75661 gaccttttta ttaatcaacg tttatttttt ggtgacgatg cgattatgcg ttggtattgc
    75721 atgaatgtat atgaagagca tatttctaat ggaaatatac gctatgaaaa aatagaacct
    75781 gaaactagaa aaacggatgg ctttttttca ttccttcatg gtttgaattt tttagatgat
    75841 atttatgatt ctgctcctgt aacagtcaca aatagctcag tagaaaatac aggaactgga
    75901 tttactcctc tagtattcta acttgaaagg aggtgagaaa gtggggattt ttcaaaaggc
    75961 ggtaggatac ttcacaaaaa aagcaacggt tcctttagaa gaatactttt gtaaattgca
    76021 agttgatttt gtgtatcgaa aatttgcgat tgaaacttgt attgatttga ttgcaaatgc
    76081 gatgagtaaa gcggaattca agtcatatga agatggaaaa aataaaaaga atgatcttta
    76141 ctataggctg aatgtagctc ctaataagaa aaataatgca acagaattta gaaaaaaact
    76201 gatcaggaga ttaatattct acaatgaagt attgatcgtt tctccgtcta ataattctag
    76261 cgaaatattt attgcggata gttgggatgt cacagaatat gcattgaaag atgatgtgtt
    76321 ttctcaagtg caaattaaca acatagtcct tgatagagaa tttctagaaa gtgatgttat
    76381 ctatataaaa tacgcagatc aacaaattag gcaactagtc gatgcgtatt atcaagcgta
    76441 tgggaaactc atttctagtg ccatgaatgt ttacaagcgc tctaacgctc gtagatacgt
    76501 actgaaaggg aatttattcc gaccgcaaga caatacaaca caagatcaaa tcaataaaat
    76561 gatgacatca caatttaagg cttttatgga agctgataat gcaggtgcgg tatttcaatt
    76621 acaaaatgag tacacattag aagatttcag cggaaacttc caaagcaatt caagagatat
    76681 aaaaaactta atagacgaca tctttgagat gacagcagca gcgtttcacg ttccgaaaaa
    76741 cctactaaag ggagacatga gtgggttatc ggatcaagtg gacgcttttt taatgttcga
    76801 aatcataccg attgctgaac ttattcagga tgcgtttaac gctagtctct atgaagtaga
    76861 agaatacttg tcagggaatt ttgtacgtgt ggatacaact atgatcaaga ttactagctt
    76921 caaagatttg gttgacgcta ttgatgtagg cattagaaat ggagtattta caatcaacga
    76981 aggaagagaa cgcgttggaa atgatcgctc tgataaggcg atggcagatg aaatatttat
    77041 aactaaaaac aatcaacaag tatcgaaagg aggtgaggcg aatgacgaca atgaaaacat
    77101 ttctagcagt aaagaatgaa ggcgcagtac cgcaaatttt tattcaggga tttattggtt
    77161 ctagttggtt ctttgaaggg aatactgaca agggaatcaa aaatattttg gatagtctag
    77221 gtgatcaaga agaaattgaa gtagtaatta attcaaacgg tggagacgta tttcaaggga
    77281 ttgctattgg gaacttactt aagtcaaata aagcaaaagt taacgttgtg attaacggct
    77341 tagccgctag tgctgcttca attatcgcaa tggctggcga tactataaaa atctacaaca
    77401 atgcacaatt gatgattcac cgcgcttcca catacggaga aggaaatgtc gatgacttcc
    77461 gtacgattgc tgaccaactg gaatcaattg ataaatcggt aaaggcttca tataaaacac
    77521 gattcaatgg cacagatgaa gcattgcaag aacttcttga aaaagaatcg tttatggatg
    77581 cagaaacagc tttgagttat ggattggtcg atgaaattat cgatgcagaa aatagctcag
    77641 gtactgaagc taaaaaagaa caaagcgttg aagaaatttt gaatgacgtt aaagaaaaaa
    77701 gagcagaaaa aattgctgca tttacagcag cattaaataa aacatttgga caaggagatg
    77761 taaaataatg acagttaaaa atttaaaagg tgtaacagct gcaagcgacc aattgatgaa
    77821 agcttttaaa gatggtaacg aagaatcttt tagcgcagct atggtaagct tatctaagga
    77881 aattcaggat aaaattttag aagaagcaac agcaaaaaat caagatcaat tagtattaat
    77941 gaaccgtggt cagcgtgtat taactacaca agaaacaaaa ttctataacg aagtagtgaa
    78001 aaacgaaggt tttgcagggg tcgaagaatt agtgccagct actgtatttg aacgtgtatt
    78061 tgaagattta gaacaatctc atccactatt gcaaaaaatt acttttgtta acacaactgg
    78121 tgtaacagaa tggattgtgt cacgtggagt caatccagca tggtggggta aactttgcga
    78181 agctgttaaa aaagttttag ataatggctt tgatgtaatt aacatgaagc agttcaagct
    78241 atcaggttat attcctgtat gtaaggcaat gcttgattta ggtccagtat ggttagatcg
    78301 ttatgtccgt actgttttag tagaatcatt gagaattgca ttagaacaag caattgttga
    78361 tggtactggt aaagatatgc cagtcggaat gatgcgtgac atgagcaaac aaactagcgg
    78421 agaatatgct gaaaaaaaag cagaacctat tacagcttta gatgctgtaa ctatgggcgg
    78481 tttgatggcg cgactatcaa aattcaatat cgaaggtgtg aatgatccga tttatcgtaa
    78541 tgtgaatcct tctgatgtgg tcctaattgt gaatccaact gattactggt ctaaagtatt
    78601 cccagctaag actgtactaa ctgctaatgg agaatacgta caagtattgc cagtaccagt
    78661 ttcagatttg cagtcaacgg ctgtgccaga aggaaaagca gttattgggg tagcctcaga
    78721 ttacttcatg ggtgtaggat ctacactaaa aattgaagct tcagatgaat accattttgt
    78781 tgaagacgaa cgcatttatc tagctaaaca atatgcaaac ggtcaaccta aacgtaacga
    78841 tagtttcatt gtattagata ttagcgcttt gggaactact actacaacta caaaaccaac
    78901 aaccacaaca actacaacac aagcgtaggt gatcagaatg aagtatattc tttgtcagcc
    78961 ggcaatcaat cggtttaaat gggagcttga agtttgttta actaatctga agaaactagg
    79021 aatcaaagat atcgtattgc ttttcagcag acacgatgat cagattccta ttttttttga
    79081 gaaggaatat ggtgttgaag ttcatgtgta cgatgatctg cgggacgaca aagagtatat
    79141 tccttcgatt aaaccatatt tatggtggaa atatttagaa gaagatcatt cgcgtgagga
    79201 cgaccgatat ttctatatcg attcggatgt cattttcaat aaaagaatta atttgcgcaa
    79261 attgccttct aaagatgatg tttggtattg tagcgactgc tgtagttatc taagtcttga
    79321 ttatattaga agctgtgaaa acggagaaaa tattctaaaa gatatggcaa acattgtaaa
    79381 tgttacagta gaatctttgg aaactataaa cactaattca ggaggcgcac agtgggttat
    79441 taaccgtcct aaagcgaatt attggaaaaa ggtttatctg gattctaatc ggctatatcg
    79501 ctaccttaga gggcaaaaaa caaatataca aatctggaca gccgagatgt gggcacagct
    79561 ttggaacatg atgtatttca atattggtcc taaagttcac gaggaattag acttttgttt
    79621 tgctactgat ccaatagaaa aagttaaaga agtaaaaatc ttacacaatg ctggagtaac
    79681 aacaaacgat gaagatttat ttttcaaagg gagatacgtg acttctacgc cttttgatga
    79741 agatttatca tttgtaaaca agaaaaaatg ctcttacgca tatgttaaag caattaaggc
    79801 ggtggttaga tgacgcctga acaagtgact gaagaattgc taatagctgt gaaggataat
    79861 atttacgtta cctggaacga agaagatgag tcaattaaaa agatgatagc taaaaatgct
    79921 gtttatcttc aaagtaaagt gagtacaaca ctttcttttt ctcctgaaag cttagaatac
    79981 ggattgctaa tcgaaagatg tagatacgac tggaatcgtg ctttagatga gtttgaacaa
    80041 aatttcgcta gtgagttatt aggtttcatt caacattatg cgctacaaga atatattgca
    80101 ggtgatgtga atggcgaata atcgtagact cgaagaaaca ttcaacgatg gttggttaaa
    80161 gattttgacg caaactacca aaagaaatga actaggaaaa aagattggtg tagaagatac
    80221 agaaatcact tctttaaaat ttagaaatct ttccatgaga gatagtgata taacagctat
    80281 ggatgcgatg ggatcgaaat taactaagaa agtaaagact ccatttcatc caatcgccaa
    80341 gaaatttaat aaagatcaat attttatcgt aatcgatagt atgcgttaca acgttatcta
    80401 tgccgattac gataattttt atatctattt ttatcttgaa agtgtgggtg aatatggtga
    80461 ttgataattc taaagaaaaa gaacgtttaa ataagcaaat ttctgctatc aaaacttcct
    80521 tagaagagca ttttggcctc aaactctttc aagactccgt aggcgaggat gagctacctg
    80581 atgattttaa ttacttcatt ctcgaaacag gagaaataga aatgatcact gagccaaaat
    80641 atagcgtggg tcaaaatcta tatctaactt tctattcaga aaatagagaa gatttaacag
    80701 gagactcact agatattatt tcattgattc aaaatcgttc gattcgtttt cagagaatgg
    80761 atcccaatca tttaaaacta gagaaccaag atcgctatat cgatcaattg gtatttacgt
    80821 ttagacgatt attgaagagt gattgtcatg gctaaaaata gttgggagct aaaaataaat
    80881 ggacatgatg aacttcttgt gcggatggaa cgctattcaa gcgagagcga acgactgatt
    80941 aacgaagcat tgaaatcaaa aggttcggct attgcagtgg ataggattac agaaaaaatt
    81001 cctgtttctg aagcagattt aagaagaggg caccaacacg caaaaaatag tcgtccactt
    81061 aagactcaat acattaattt gggtttcatc attagaccta caagaaaatt tgagtattta
    81121 aaatatcctg atttggggat aggtacttct aaaagaaatc agccggacga atttatgaga
    81181 agaggattag gtcttgcact tgatccaatt acagaacttc tgattcgtca attcgataaa
    81241 ttaaataaat agggggaaca acaatggcta aaacaaaaac tgtagtaaca acgttcgata
    81301 acgtaagtat caaacgaatt gcttttaatt ttaagaacgc aggaaatgca atcgcaacga
    81361 attgtaacgg acaattagat ggcgaaacag aaatgcaaac ggtggttaaa aaatgtggag
    81421 cgacagaagt aaaatcaaaa tctaaaccaa tcaatatgac ggtaacaatt actgcacatg
    81481 taccgatgga agtttatcga cgtttcaatg ggttgaaaca agatggacgt attaaaccag
    81541 gcatttactc ttacggtcct gattccgtag gcgaagattt ctcacttgct gcagagatcg
    81601 tggatgactt cgaagaaaat agaaagttag ttggtatgtt agcatgcact tcgaatacag
    81661 gattaacatt ctctattgaa aatggtgcgg atgaagtagc tgcgttagaa ctagaaacaa
    81721 aagttatgca agatgaattt ggtaaatttt atcatgaagc aattgttgca gaacttgaag
    81781 aagacttaac agatcaatgg atgacgaatc tatctgctga tgtgattaaa aaaacttcag
    81841 ttgtgacaac tacggccact caatcacagt aaaaaaaacg gaggtagcga aatgaacgaa
    81901 gattactcaa aaattgaact aaacgatgga acaattttga atttagaacc taaactgaat
    81961 atcaagaaat tattgatgat caatagagat tttaacacag acgagtttgc aaaaatgact
    82021 gtgggaaaag gatccatgga tatttctgtt attcaaggtg caaaggctgt gtatattgct
    82081 taccgccaag cgaacatgac tgattatatt tcattcgatg aatttatcga taaatgggat
    82141 tttgatatgg ctactgccag ctatatttat caattgatga tgttcaaaca agcacgcgat
    82201 gcttatcaaa aagaatttga aaaagcaaat aaggaaaaaa agcttcaaaa gtaaaaattc
    82261 caaagctctt agttgaaacg tgggtcgatg tctattcgat gttgaccgac gttttttcta
    82321 tgccttcaga tttggtttta agcgatatct gtttagatga cattttgcaa atggcttaca
    82381 acaagagtgc ttatgaagga tggaaaaact atgcaataaa ccaatcccag aaaaactaaa
    82441 gaaaggaggt aaaaaatggc taaaaagaga acagaagcag aagtaacttt catagctaac
    82501 gatgacggat tgaaatctac gttaaaagaa atcagtgctg aattaactaa aaatagagca
    82561 gaattaaaac tagaacaagc tcaattacaa cagactggtt ctgaatcaga caagttagga
    82621 agtaaattat cttctttaga aaagcagtat gaattacaaa gtcaaaaagt tgaagtaact
    82681 agccaacgtt tagccaatgc gaaaaaatat tatggagaaa attccaccga agttaagaaa
    82741 cttgaaagag aactgattaa tcaacaaaca gcgcaacaac gtttgtcaaa cgaaattgat
    82801 aaaacgagta atgcactagc tcaagcaaaa ggcgaaatac agacgtacga gtctacaatg
    82861 caacagttgg atagcgaaca aaaaaatgtt caagctagtg cttctctgat tgaatccgaa
    82921 tacaaaaaat ggcaagcaac tgctggtcaa tcagcttctg aagccgagaa attagcgaaa
    82981 gcccaagaat atgtttctca acaatctgaa aatgcggaga aaacgataga tatcctaaga
    83041 cgacagttag aagctacaca gtctgaattt ggcgctacat ccacagaagc aatgcagatg
    83101 gaagcgaagc ttaatgatgc tgaacgtgaa tttgaagagt taggacaagc tgctaaaaat
    83161 gtagatacaa ctaacttgga cgatatcgga agcaaaatag atatgaataa tttaatggaa
    83221 gcttctgacg ttttaagcga cattggcgat aagcttacag aattagggaa acaagcagtg
    83281 gactctgcta acagtgtagg tagttcccag agtaagatac aagctaattt tggtttgtct
    83341 aaacaagagg ctgaagaatt aacgaatgta gccagagaca tttattataa aggttttgga
    83401 gaatcgttag atcagtccac agatgcattg attttggtaa agcgtaattt aggagattta
    83461 aataatcaag atttacaaaa tatcacggaa caagctatgg tcctagaaaa caccatgggc
    83521 gctgatatgg atgaaacgtt acgtggtgta aatggcttaa tggtcaattt cggcttgagt
    83581 gctcaagatg caatggattt aatggtttcg ggtactcaaa acggtttaga taaaacgcac
    83641 gaattaggcg acaatatggc agaatatagc caattatgga gtcaaatggg atattcagct
    83701 gatgaaacgt tcggaatgct tcaaaatggt ttagatgcgg gtgcttataa ccttgataaa
    83761 gtcaatgact tagttaagga aatgggaata tcgttaacag atggtcgatt tgagcaaaac
    83821 atggatatgt ttagtgaaag tactagaaaa gcttttgaag agtggaaaaa tggcggagga
    83881 acacaaaaag acgttattaa ttccatgatt caagatttta gcaatatgga tggtcaatac
    83941 gaccaattaa ataaagcttc gacaatttgg tctgcgcttg gcgaagataa tgcgatgaaa
    84001 gttgtccaat ctttaactga tgttaaccat acatttgatg atgttagtgg atctgcacaa
    84061 aaaatgaatg aagattctac tactccgttg caagagttga acgggaaaat agctgaatta
    84121 aaggattcat tagctcctat aggcaacaca atcatagatg cactcgaacc agtaattgat
    84181 tttctaggaa agatggctga tgcgtttaat aatcttccac aaccagtaca ggatttcatt
    84241 gttgctatag gtggtcttac agcagcattt ggcatactgt taccggcaat actagccgtg
    84301 tcatatttat ttggtccgat gatgcttata attggaggaa ttatagctgt tatagcaggc
    84361 gttattgtgg caattaagaa ctggggtgca attactgact ggtttagtgg tttatggaaa
    84421 aaatttactg attggttggg tgatacttgg gaaagtataa aagacggagc ctcatcagtt
    84481 tgggatgggg ttaaagaaac ctggtctgga tttgtagatt gggttcaaga tatttggcaa
    84541 ggagtttctg attggtttgg agagctatgg agcggattag ttgaaggagc ttccaacatc
    84601 tggcaaggag tccaagaaac ttggcaaaca ttcgttgatt gggtttcaaa tatttggaac
    84661 ggagtcaaag aagtatggtc gattatttgg gcagacattg taggaattgt tcaaatacca
    84721 tggacattaa taacgtcatt gattcaagct ggtattaata ttatcgtggg tatttttgat
    84781 gtagctggac agttattggg cgcagcttgg caagctgttt ggacacctat ttctgatttc
    84841 cttaaaaata cttgggatac tatgacacaa tggataagta tcgcttggaa tgggattgta
    84901 actacattcc atactatatt tgatccagta gtggcatggt ggaatggtat atggacagct
    84961 attagtacta cggcttcaaa tatttggaat tcaattagtg caacagcttc tagtatttgg
    85021 aacagtatca agaatacaat cactagcttg gtacaagcag ctgctacagt aattcaaaat
    85081 atttggtcaa ctgtatctag ttggttaggt ggaatttgga attcaatcag ctctacagca
    85141 tcaaatatct ggaatagtgt gactagtagt ataagcaatg ctataaacgc agctaaaagt
    85201 gccattcaaa gtgtttggaa tagtatatct tcgtggatta gcggaatttg gaacggtatc
    85261 aaaaatactg ctttgaatct ttggaatgga attacaagca ctattagctc taaagtaaac
    85321 gatggaaaaa atgcaatttc aagcggttgg tccaatctaa caggtattgt ttccgacata
    85381 ttcaataatg ttaaaagtac aattgctaac atatgggaag gcatcaaaaa gactgttagc
    85441 gctccaattg attggattag agacaaaatc agtggcattt ttgataattt gaatatttct
    85501 ataccacata ttccgttacc ggaatttatc atggaaggca gctttaaccc gctaaaaggt
    85561 caaatccccc atttgcgtgt aaaatggcat gctaaaggag gtatctttac taaaccaact
    85621 ttactaggtg gaatgaacgg tgtcggtgaa gcaggacctg aagcagtttt acctttgaaa
    85681 agatctgttt tgcaagaaat tggtgatcgt atcttgagta gcacatcagt ttcatctagg
    85741 gcacaaacga ttcaacctgt gaataactac gaattcaatt tcacaattga tggtaacgca
    85801 gatgaggtta ctatgaagca aacaactcaa caaatcattg atagcattac aaaaattcaa
    85861 aatgataatg cttcggcatg gcgttaaaca ggagagtatt tctcctgttt ttttagtatt
    85921 aaaaaggatg tgaaaaaatg actgattgta tacattctat aatcgatgga tttcctgatt
    85981 atttgcataa attggcttta gctgaaagac caaccatacc ttctccaaaa agacagagag
    86041 ttgaaacttc tgttttaggt aggttaggtg gcttagtaca agattactcg tttgaagata
    86101 tgtcgtttac attgcactat aactatttag aggatgtgga agaccatcaa gcgttcaagc
    86161 aatcgtttta tatcatgcgt cattggttaa actatgcaaa gaaattagaa ttctctgacg
    86221 atcccaacgt ctattacgtt atccagacta tcgatattgg ggatgcagaa aacgatattg
    86281 ttgaatgggg agagttcgat gtaaatatta ctgcgaaacc attcgcaaga gttcaagaag
    86341 atgtacctat aaccgtagat aaaccacagt catttaactt gctgaataat agtttagaag
    86401 aaagttttcc aaagattatc atcactcctt cagctacttc atgccagttc atcttaaatg
    86461 attatgtgtt tagtttcgaa ggcttagtag caggaactga tgtagtcatt gatagtgatt
    86521 tgatgctttg ctacgaagag caatcggacg gagatatttt agatcggtcc aacaaaatga
    86581 agaccatgca atatccgaca ttgcaagtgg atatcaatca ttttaattgc actggtttga
    86641 gcaaaataca aatttatcgt aacgggttaa ggtaggtgaa atagatgatc gataatttaa
    86701 taactattta cgataaaaat gacgcgaata atttagctga acatttatat gatacgcaag
    86761 gtttaggcgc tttgtcagac tggttaacag ctactgttag caataaacta aacggagccg
    86821 agatatttca gggtacttat tcaataaacg gaactaatgc agatttgatt gtagaaggac
    86881 gtattattca gtgttatgta gatgaaaatc gagcaaaaca gcgtctacgg atttattatg
    86941 caaaaacttc tgtaataggc aatacgatag aagtaaaagc tgaacctatt ttcaatgata
    87001 taagaaaatc ggtgttgaat aaatatgaca gcggaacaga aaagatcact gctactcagg
    87061 catggcaaaa cgcaaaagtt ttagcgaaac cagctatccc ttcgcagttt tctttctcgt
    87121 cattagtaga tacgcttgct aatgtgaaga tagaaaaggc gaatttttta gaattctttg
    87181 gtggaaaaga gggatctatt ctagatcgat ttcatggtga gtttctaaaa gataataaca
    87241 cattacgtca tgaaaaaagt ctaggtacgg atcataaaat caaagcgatt tatactaaaa
    87301 acttaactgg tcttgactta gagattgatg ctcaaagtgt tttagttgga gtttatccat
    87361 tcattagcag ctcttcagaa ggagaagacg agatcactct accagaagaa gttattttca
    87421 cggattacgt ggatgattat cctgctggat atgtttcttt tgttgatttt aaagacaaag
    87481 cgactgatgt agccacatta agggaagctg ctaaagactg gttgaaaaca aacatagata
    87541 aacaaaaacc acaagtgagt ggttcgattg aattagtacc attgaggcat caaagaggct
    87601 atgaaaaatt tgttgatcta gaaaaagttt cgatgggtga cggagtagat gtgtatcatc
    87661 cacagttaaa agtgaatatg tcagcgagaa ttgtggaata tacgtttaat gttctaacca
    87721 attcatacga taaattagtt gtaggaaacg tcaaaacaaa cttcttagaa aacacagaga
    87781 ataatgtcag caatttgatt aatgatgcca ttgatcaatt gaaaaacggt ggcgaaatca
    87841 gtgatttact caatgatatt gtagatcatc aaactgatat gattactggt caaaatggtg
    87901 gttatgtttt attagatcct aaagaagcgc ctagtcgtat tttgattatg gacacaccag
    87961 ataagaatac cgcaaggaat gttttacaaa tcaacaatgc tggtattggt ttttctaaaa
    88021 ctggcattaa tggaacatat gaaacggcat ggacgttaga tggcggattc aatgcctcgt
    88081 ttattacggc tggtgaaata gtaggaatta ctattagagg tactacatta attagtgatg
    88141 gtgctgatta tagaacaagt attgctaatg gcaaaatgac ttggtactca aaaaaagtta
    88201 acaaagatat tatggagcta gaagcacgtg attatgtaag tgctgatgcc ggtattgtat
    88261 catacaccat gaaaactggt ggtggtttca tgattagaaa tccacagggt aacttggttt
    88321 ttagtacgtg ggataatggt aataacagac cgtttctatc ttttggtgcg cccaatttca
    88381 ggtatagcaa tgctagttat gtaacttctg gcgacggtag ttctttaagc attaatggta
    88441 gtgcgggtaa ctcatgggaa tttaaggtag ctggtaggac tatgaaattt actagtgatg
    88501 gtatgctaac gttaccaggt tgtttttttg gttcatggga agatgggaaa cttgctaggt
    88561 ttgaacaatc aacggtacaa gtatataaag attttactgt tagaggtact aaaaactcaa
    88621 ctgtaccaac agaacattat ggacaacgac tattgaacgc ttatgaaact ccagaatatt
    88681 atttcgctga ttatggggaa gccgttacag gtgacaatgg taaagttcgt gttgatattg
    88741 accccatgtt tgctgaaaca gtaaatctaa gtcggtatat gacacatgtg acacctacag
    88801 aactagtttt gtgtgctgtt actcatgaag atattgacca tttcatcatt gaaactagta
    88861 agccaaacgt attagttaga tggaatttag tggcacaccg tctagggtat gaagatatta
    88921 gattaaaaga ggatacagca tatgatagca cagtgcttga ccaaaaacgt ttttaaaacg
    88981 aagacaagga ggtatataaa tggctagcag tttatataat ttggctttag atttcagcaa
    89041 agaattaaac tacaccaaag ctattatggc tcgtcaaggt gataaaggga ttacggtgac
    89101 ggttaaaccg tttctaaatg gcttgcagat ggatacgagt ggcggaacat ttactttaaa
    89161 aggaacaaca ccatctaacc gttacgtaga taatgttgca actagtgtaa ctagtgaaga
    89221 agtcacgttt tctcttgatg gcacatttat gagtgaagca ggatattata aacactgcta
    89281 cgtagaatat agaaaagaca atcaaatttt aacaacgcaa gatatcattt ttttctcact
    89341 aggagtgtct gacatttcgc aaggccaagc cgatgaatat gtttcgcaat tagaagagtt
    89401 gattcgaaag tacaacgaaa cttttgatgc ttttatggct gaaatcaaag gtagagtgga
    89461 tagcttaaat caacagatta ctgatttaac tggtcaagct aaaacgctac aagacaagtt
    89521 agatgctctg aaagaagaaa tttctaagtt aggtaactta caagtgatgt acagtaacag
    89581 catcgacttc ggggactatg attattcgga gaacccgaat ttaatgccat atattacaga
    89641 accttgggtt ggacctttgt taggtaatgg acatacagtt aaagatagtg ttaaaagggt
    89701 tataactcat actaaaacta gaacagctaa ttccggcgac atattatcgc ttggcttagg
    89761 tattccgtgt acagcggaag ctaataatag gtatcttata accactttac gaccatctac
    89821 gacatacaca ttaagcgtta ctatgagtgt cggttcagat tggactggag agaccaatac
    89881 tataggggtt aggcttagat atttaaatga acaaggtggt atagaactgc ccattaatgc
    89941 attaatacca gcaaatgtag aacgcgataa aatggtcact catacattta ctggtataac
    90001 aaaagataat gtaactagca taacaaactg ttatgttgaa atattctcac ttaatagtga
    90061 atataaagga acggttagtg tcagctatga cgttaagtta aaagcacact accctaactt
    90121 actagatggc ccttactggt taggtaaagt tcctttaggc gagaatattg ctgaccctac
    90181 agttgtcttt ccacacaaaa ctagtgaata tatggtttat ggtagacgca atacagaaaa
    90241 ctatatcgct gaccaaacat ataccatatc aatgaaagca actaaactaa cagttcaatc
    90301 gtttgccgtg tatattgctg ctggccgcgt taaagtagga gacatgaagc ctactgaggg
    90361 gttagctaat acatgggagt taacttttac tgtaactaag caacatatag atagtggggt
    90421 aactaattat ctggaaatat accaataccc gtcagctaca aaaggagctg ttcaaattga
    90481 gtggctcaaa ctagaaaaag gcaatactcg aaccccgaat attagtgagt ataaatatcg
    90541 tggtactggt atgcgtgatt caaacaatcc aaaagattat gtttgggatc tagcaccaga
    90601 atatgtcgaa gataatttgg ccacagatat taaaatttct gaaattactg gtaaagcaaa
    90661 caattatacc gatgggaaag tatcggagat taattcgcag ttgactgctt caattaatga
    90721 agtagacacc acagctaagg atgctcaaac aaaagcgaat gctaatgcga ctgctataga
    90781 tgaattagac aataagatcg atgaacgcat taatgataca gctactacca cattaacagt
    90841 tacaaacggg aataccggat cagcaaagct ttatcgtgaa ggaaaaacag tttctatata
    90901 ttttgtggct ttaaacggaa aaagcagtgg tggaaatgat tcaacgatac taacaattcc
    90961 agaaggctat cggccaccaa ttagttttga gcaactggtt ggctcgatag accgttctac
    91021 tttgaacagt gctcagttat ctattggtgc agatggagcc attaaatggc gaagaaactc
    91081 aagttatgga tcggattata cctttgcaat tacttacacg atttagaaaa gcgtgaatcg
    91141 atatgaaggc agcatataga ccaattgaac cttacggatt cgagcaaatc attgtgaatg
    91201 atgaagaaca tttaccggaa gaatgcacag aagtcgaacc accgattcca aattggaaac
    91261 cgaaattcaa ttactgggag ggaaataaat gaaaaacatt tggaaatatg gacgtactgg
    91321 cggagagtac gcaggaaaag tattggacga catgcttgta tccgttcctt acacagatca
    91381 gccaccgctt gaaggaattc gtgctgatgg cgaaccgtta acaatcgctg atcaaatgtt
    91441 tgatcctaaa ttgaatcaat ggattatttt agcgaacgca ctagatcaca acgatttaaa
    91501 caatctcaaa gcaatgtatg agtcgttaga aaatgagaac ggcgatttaa aacagatcaa
    91561 tgccaaactc atgctaagcg atgtagcaat taaacaggaa aatactgcat tgaaagaaaa
    91621 agcggatagt ttagcacaaa tcaattcaaa aatgatgctt gcttcgttac aaaatagcaa
    91681 agacatttca gaaattaaag agcaactaaa tccagcttca aagggaggtg agtagtatgt
    91741 ttagttttag cgatgtgaaa atgatgtatg attggggctg tttcactaac gaacaagtaa
    91801 tggttttcgt tccgttgtgc attactgaag aaaaagcaga taaaatcatt agcaaagaag
    91861 agagcgcatc ttaattgatg tgctttttat tttgattcaa ggagttgtca catgattaat
    91921 ttaggggaat ggggagcgat agcaggatca ataaccgcta tcgtttcttt gattttatta
    91981 gtaataaaac caattactgc atctttctcg aagattactg agactctttc aaaagtaagt
    92041 cacaatttag atttgctgac taaagattta gaatcgagca aatcagatcg attgatgatt
    92101 catgaagaac taaagaaaca cgatgaaaga ttagatacac atgcagaaaa attggtagaa
    92161 cacacgcaac aaattaaaac tttatttagg gagagaagaa aatgaataat aaaacgttcg
    92221 aagtactaaa atggttcgca ctggtaatta ttcccgcact agctactttc gtggggttag
    92281 ttggtaaagc gctcaattgg cagtacacag atatctgtgt tgtcatcatt actggttttg
    92341 gcgcgttttt agggagtgtg ttgggtgtat caaatcgaac ctacaaaatg ttctcggctg
    92401 aaagcgaaga aggaggaaac aaatgaaaaa gaaaattact attactgcga tgagcctgtt
    92461 aacggctctt tttttattac ccattaatac gtttgcttat actattaatg acgagtataa
    92521 tttagcgccg aatcaaggag actccagatt agcaattcct aacaaaatta ttttgcacga
    92581 aactggaata gatgcaccag caagaaacgt agccgccaac atgaaaaata attataacgg
    92641 aagcaatcct tatactacag atgttattgg tgacggtggg attgtttacc gtgtgggtga
    92701 gcaaggatat gtttcgtggg gagctggtaa cgctaatcct tatgcgcctg tacagattga
    92761 attacagcgc acatatgata aagcattgtt tgaaaaaaac tatcgagctt atattgaata
    92821 tacaagagat agtgcaaaaa aatatggaat tccattgact cttgatcaag gaacttcttt
    92881 atttacaaaa ggaatcattt ctcatttgtg ggtgacaaat tatgtttggg ggaaccacac
    92941 agatccatat ggttacttat cgcaaatggg agttagcaaa gaaaagcttg cttatgattt
    93001 agctcatgga tttaccgatg aaaatccaac aacttctgaa aacaagcctg tcattgatcc
    93061 aacacgagct ggtgcagcta atcctacgct gacagatgga acaaatcacg cccacattga
    93121 tcagtttggg gaaatcgaaa acgcaaactt gcatgtggct ggatggcaca ttgctaacta
    93181 taaatacgag tatattttca ttatggacta caatactggg aaagaattag ctcgagtaag
    93241 agctgatgga atttatagac cagatgtaaa ccaagcttat aatacttctg gaaatgttgg
    93301 ttatcatgta tctttcaata tgcgtaattt tcctagtaag aaagtctatg taatgatgcg
    93361 ggcaacgaat gatccagagg gaaacactaa aggcggtgcg caagatttcc atgacaaacg
    93421 ttggtattta aatattccta aacgataaaa atagctcctc gttgaggagc agtacataac
    93481 tatattgaca actataaaaa ttattcgata aaatagtgat gttatcgcat atcttcacta
    93541 tcacccataa atagtcacac tccaagctat gcgataacag gtttgttgcc acacattcta
    93601 ctggttgatt gtttatggct ttatgtggca acaaccagta cccttagctc agttggtcag
    93661 agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacagggtac attaacgtag
    93721 ccatttgaat cgttctgtgt tagaattttt ttgaagagta ttatacaagc taaagctttt
    93781 cttcattgcc actcaaatga gtggcttttt tatgtatcct tttatggatt aatgaaagga
    93841 tgtttcacat agttatactt ctgtatattt gaaaagtttt actttgattt ttaaatagaa
    93901 agacatttgg gttaaattgt gagataataa taaagaagag tttaaagcgc accccaaacc
    93961 acttccccat aagtgtgtta cgctttaaac tcttttatat ttgaagccat taaaaagcat
    94021 accatatttt tgaaaaaaag tgagaaaaaa ggcttacaat tggagtggta gttaattagt
    94081 gacttatttt tgattttata gcactgatac tataaaatat agatatcatc atattacaca
    94141 atcttaatac taacttaaaa aatatctcct ttcacaagta tggtgataaa attcgttccg
    94201 ggctaccttt ttaggtagcc tactttaatc tttatacctt tctggatcaa cgaaagtata
    94261 ctttatatag tcataacgcc gatgatcgct acgtgcgtcc ggcacgtcag tcatgaatcg
    94321 gctacactag actagacaga aaaaataagg tgtgtagaat aataaaaaac acactggagg
    94381 atttttcatg tcaagacgtc aacgaagaac ctattcaaaa gaattcaaac aacaaatcgt
    94441 cgatctctat ctcgctggta agcctcgcgc agaaattatt cgagagtatg agcttacgcc
    94501 ttcttctttc gataaatgga tgaagcaagc acaatcaacg ggctcattca aagaaagaga
    94561 caacttaaca ccagaacaag cagaattgat cgcactaaga aagaaaaata agcaactcga
    94621 aatggagaat gatattttaa agcaagcggc gctgatattc ggacgaaaag acaagtaatt
    94681 gatgccaaca agcataaata ttccatatca gcgatgtgca aaattctaaa tatttctcgt
    94741 caaacctact attatcaagc gaaaccgatc gaaaatgagt ccgacttaga agagatcgtt
    94801 caggaagagt ttattcgaaa ccgaaaggct tacggtaccc gaaaattgaa gaagtgttta
    94861 gcaaagcgtg ggcttcaact cagtcggcgc cgaatcggtc gaatcatgaa acgccgcgga
    94921 ttgacatcta cctatacgat cgctcatttt aaagggcaac gaacagcttg taatgaagcg
    94981 aaaacagcga atgtattaga tcggaccttt acacaagaac agc
//
LOCUS       DAKCAA010000004        79106 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000004 DAKCAA010000000
VERSION     DAKCAA010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 79106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.004"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            75..1073
                     /locus_tag="OUE31_000312"
     CDS             75..1073
                     /locus_tag="OUE31_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221349.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLIFLLTYRKC
                     QNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLS
                     LFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVW
                     ASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(1313..1396)
                     /locus_tag="OUE31_000313"
     tRNA            complement(1313..1396)
                     /locus_tag="OUE31_000313"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1360..1362),aa:Leu,seq:gag)
     gene            1451..1630
                     /locus_tag="OUE31_000314"
     CDS             1451..1630
                     /locus_tag="OUE31_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221350.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            1779..2996
                     /locus_tag="OUE31_000315"
     CDS             1779..2996
                     /locus_tag="OUE31_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCU0221351.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3180..4016
                     /locus_tag="OUE31_000316"
     CDS             3180..4016
                     /locus_tag="OUE31_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0221352.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            4092..5240
                     /gene="nagA"
                     /locus_tag="OUE31_000317"
     CDS             4092..5240
                     /gene="nagA"
                     /locus_tag="OUE31_000317"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HCU0221353.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            5461..6519
                     /locus_tag="OUE31_000318"
     CDS             5461..6519
                     /locus_tag="OUE31_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HCU0221354.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            6523..7557
                     /locus_tag="OUE31_000319"
     CDS             6523..7557
                     /locus_tag="OUE31_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HCU0221355.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(7659..8375)
                     /locus_tag="OUE31_000320"
     CDS             complement(7659..8375)
                     /locus_tag="OUE31_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCU0221356.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(8344..9129)
                     /locus_tag="OUE31_000321"
     CDS             complement(8344..9129)
                     /locus_tag="OUE31_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HCU0221357.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(9120..9869)
                     /locus_tag="OUE31_000322"
     CDS             complement(9120..9869)
                     /locus_tag="OUE31_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCU0221358.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            10167..10691
                     /locus_tag="OUE31_000323"
     CDS             10167..10691
                     /locus_tag="OUE31_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HCU0221359.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10707..12206
                     /locus_tag="OUE31_000324"
     CDS             10707..12206
                     /locus_tag="OUE31_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HCU0221360.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(12294..12896)
                     /locus_tag="OUE31_000325"
     CDS             complement(12294..12896)
                     /locus_tag="OUE31_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCU0221361.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            13000..13956
                     /locus_tag="OUE31_000326"
     CDS             13000..13956
                     /locus_tag="OUE31_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HCU0221362.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(14261..15217)
                     /locus_tag="OUE31_000327"
     CDS             complement(14261..15217)
                     /locus_tag="OUE31_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCU0221363.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            15391..15951
                     /locus_tag="OUE31_000328"
     CDS             15391..15951
                     /locus_tag="OUE31_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221364.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15944..16768
                     /locus_tag="OUE31_000329"
     CDS             15944..16768
                     /locus_tag="OUE31_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCU0221365.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16778..17395
                     /locus_tag="OUE31_000330"
     CDS             16778..17395
                     /locus_tag="OUE31_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCU0221366.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            17413..18096
                     /locus_tag="OUE31_000331"
     CDS             17413..18096
                     /locus_tag="OUE31_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCU0221367.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18779..20062
                     /locus_tag="OUE31_000332"
     CDS             18779..20062
                     /locus_tag="OUE31_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCU0221368.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            20078..20965
                     /locus_tag="OUE31_000333"
     CDS             20078..20965
                     /locus_tag="OUE31_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0221369.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20982..21818
                     /locus_tag="OUE31_000334"
     CDS             20982..21818
                     /locus_tag="OUE31_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCU0221370.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21821..22444
                     /locus_tag="OUE31_000335"
     CDS             21821..22444
                     /locus_tag="OUE31_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221371.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            22441..23733
                     /locus_tag="OUE31_000336"
     CDS             22441..23733
                     /locus_tag="OUE31_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCU0221372.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      24092..24189
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            24305..24886
                     /locus_tag="OUE31_000337"
     CDS             24305..24886
                     /locus_tag="OUE31_000337"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCU0221373.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24889..26196
                     /locus_tag="OUE31_000338"
     CDS             24889..26196
                     /locus_tag="OUE31_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HCU0221374.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMILISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26612..27100
                     /gene="purE"
                     /locus_tag="OUE31_000339"
     CDS             26612..27100
                     /gene="purE"
                     /locus_tag="OUE31_000339"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HCU0221375.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            27093..28217
                     /gene="purK"
                     /locus_tag="OUE31_000340"
     CDS             27093..28217
                     /gene="purK"
                     /locus_tag="OUE31_000340"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HCU0221376.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            28230..29525
                     /gene="purB"
                     /locus_tag="OUE31_000341"
     CDS             28230..29525
                     /gene="purB"
                     /locus_tag="OUE31_000341"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HCU0221377.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKRMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29705..30082)
                     /locus_tag="OUE31_000342"
     CDS             complement(29705..30082)
                     /locus_tag="OUE31_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221378.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            30338..31066
                     /locus_tag="OUE31_000343"
     CDS             30338..31066
                     /locus_tag="OUE31_000343"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HCU0221379.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            31066..31320
                     /gene="purS"
                     /locus_tag="OUE31_000344"
     CDS             31066..31320
                     /gene="purS"
                     /locus_tag="OUE31_000344"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HCU0221380.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            31322..31993
                     /gene="purQ"
                     /locus_tag="OUE31_000345"
     CDS             31322..31993
                     /gene="purQ"
                     /locus_tag="OUE31_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HCU0221381.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31994..34216
                     /gene="purL"
                     /locus_tag="OUE31_000346"
     CDS             31994..34216
                     /gene="purL"
                     /locus_tag="OUE31_000346"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HCU0221382.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            34201..35640
                     /locus_tag="OUE31_000347"
     CDS             34201..35640
                     /locus_tag="OUE31_000347"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HCU0221383.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35663..36715
                     /locus_tag="OUE31_000348"
     CDS             35663..36715
                     /locus_tag="OUE31_000348"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HCU0221384.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36712..37290
                     /gene="purN"
                     /locus_tag="OUE31_000349"
     CDS             36712..37290
                     /gene="purN"
                     /locus_tag="OUE31_000349"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HCU0221385.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            37287..38822
                     /gene="purH"
                     /locus_tag="OUE31_000350"
     CDS             37287..38822
                     /gene="purH"
                     /locus_tag="OUE31_000350"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HCU0221386.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38838..40112
                     /gene="purD"
                     /locus_tag="OUE31_000351"
     CDS             38838..40112
                     /gene="purD"
                     /locus_tag="OUE31_000351"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HCU0221387.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            40234..41148
                     /locus_tag="OUE31_000352"
     CDS             40234..41148
                     /locus_tag="OUE31_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCU0221388.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(41281..42846)
                     /locus_tag="OUE31_000353"
     CDS             complement(41281..42846)
                     /locus_tag="OUE31_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCU0221389.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKILQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42839..44290)
                     /locus_tag="OUE31_000354"
     CDS             complement(42839..44290)
                     /locus_tag="OUE31_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCU0221390.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(44304..45320)
                     /locus_tag="OUE31_000355"
     CDS             complement(44304..45320)
                     /locus_tag="OUE31_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCU0221391.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45540..46628
                     /locus_tag="OUE31_000356"
     CDS             45540..46628
                     /locus_tag="OUE31_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HCU0221392.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46682..48208
                     /locus_tag="OUE31_000357"
     CDS             46682..48208
                     /locus_tag="OUE31_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HCU0221393.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            48210..49415
                     /locus_tag="OUE31_000358"
     CDS             48210..49415
                     /locus_tag="OUE31_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0221394.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49672..50649
                     /gene="guaC"
                     /locus_tag="OUE31_000359"
     CDS             49672..50649
                     /gene="guaC"
                     /locus_tag="OUE31_000359"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HCU0221395.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50913..52337
                     /locus_tag="OUE31_000360"
     CDS             50913..52337
                     /locus_tag="OUE31_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCU0221396.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            52798..53907
                     /gene="pdhA"
                     /locus_tag="OUE31_000361"
     CDS             52798..53907
                     /gene="pdhA"
                     /locus_tag="OUE31_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HCU0221397.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53910..54887
                     /locus_tag="OUE31_000362"
     CDS             53910..54887
                     /locus_tag="OUE31_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HCU0221398.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFILEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            54912..56555
                     /locus_tag="OUE31_000363"
     CDS             54912..56555
                     /locus_tag="OUE31_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HCU0221399.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            56563..57969
                     /gene="lpdA"
                     /locus_tag="OUE31_000364"
     CDS             56563..57969
                     /gene="lpdA"
                     /locus_tag="OUE31_000364"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HCU0221400.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            58131..58406
                     /locus_tag="OUE31_000365"
     CDS             58131..58406
                     /locus_tag="OUE31_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HCU0221401.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            58412..59179
                     /locus_tag="OUE31_000366"
     CDS             58412..59179
                     /locus_tag="OUE31_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HCU0221402.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            59347..61176
                     /gene="typA"
                     /locus_tag="OUE31_000367"
     CDS             59347..61176
                     /gene="typA"
                     /locus_tag="OUE31_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HCU0221403.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            61437..63209
                     /gene="recQ"
                     /locus_tag="OUE31_000368"
     CDS             61437..63209
                     /gene="recQ"
                     /locus_tag="OUE31_000368"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HCU0221404.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            63323..63625
                     /locus_tag="OUE31_000369"
     CDS             63323..63625
                     /locus_tag="OUE31_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HCU0221405.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            63628..64791
                     /locus_tag="OUE31_000370"
     CDS             63628..64791
                     /locus_tag="OUE31_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCU0221406.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKNFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            64817..68245
                     /locus_tag="OUE31_000371"
     CDS             64817..68245
                     /locus_tag="OUE31_000371"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HCU0221407.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            68266..69390
                     /locus_tag="OUE31_000372"
     CDS             68266..69390
                     /locus_tag="OUE31_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221408.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            69380..69817
                     /locus_tag="OUE31_000373"
     CDS             69380..69817
                     /locus_tag="OUE31_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCU0221409.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRVVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            69801..70139
                     /locus_tag="OUE31_000374"
     CDS             69801..70139
                     /locus_tag="OUE31_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HCU0221410.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            70258..70818
                     /gene="rsmD"
                     /locus_tag="OUE31_000375"
     CDS             70258..70818
                     /gene="rsmD"
                     /locus_tag="OUE31_000375"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HCU0221411.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            70815..71306
                     /gene="coaD"
                     /locus_tag="OUE31_000376"
     CDS             70815..71306
                     /gene="coaD"
                     /locus_tag="OUE31_000376"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HCU0221412.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            71296..72339
                     /locus_tag="OUE31_000377"
     CDS             71296..72339
                     /locus_tag="OUE31_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HCU0221413.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            72498..73226
                     /locus_tag="OUE31_000378"
     CDS             72498..73226
                     /locus_tag="OUE31_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HCU0221414.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            73342..73587
                     /locus_tag="OUE31_000379"
     CDS             73342..73587
                     /locus_tag="OUE31_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCU0221415.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            73584..73802
                     /locus_tag="OUE31_000380"
     CDS             73584..73802
                     /locus_tag="OUE31_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HCU0221416.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            73938..74477
                     /locus_tag="OUE31_000381"
     CDS             73938..74477
                     /locus_tag="OUE31_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HCU0221417.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            74470..76743
                     /locus_tag="OUE31_000382"
     CDS             74470..76743
                     /locus_tag="OUE31_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HCU0221418.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            76781..77827
                     /gene="holA"
                     /locus_tag="OUE31_000383"
     CDS             76781..77827
                     /gene="holA"
                     /locus_tag="OUE31_000383"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HCU0221419.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(77916..78170)
                     /locus_tag="OUE31_000384"
     CDS             complement(77916..78170)
                     /locus_tag="OUE31_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HCU0221420.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(78570..78839)
                     /locus_tag="OUE31_000385"
     CDS             complement(78570..78839)
                     /locus_tag="OUE31_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221421.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
BASE COUNT        25658 a        13518 c        17207 g        22723 t
ORIGIN      
        1 atgtttttga gaaaataaat gttaaaaatt tattattggt ttgctctata tactgtttaa
       61 taccattgac agtaatgggg gaaaccggtt ggagagcaac caccttgaac tatcagtggc
      121 cagtagcatt tagtttacta actttttatc cgttttttca actcttaaga ggagaagaaa
      181 taaatagaaa aatatattgg gtaagtattc ctttattgat atttttaact aatcaagaac
      241 aagtcaacgc ctgttttttt gttctaacaa gtatagttag tttatatttg attgtcaatg
      301 gacgatataa ttataagtta tcagtatttt caataataag cttagcagaa ttaattttct
      361 ctttgacaac tccagggaat gcattacgtg ctgcacatga aattaataaa tggtttcctg
      421 aatataaaaa tttcaacttt cttaataagt tagatttagg tatttcatca tttggaaagc
      481 cgtttttttt agacatgaat atcttatttt tattgctatt tttcttaatt ttccttctaa
      541 catataggaa atgtcaaaac tattatgtgc gtatattgac tgcattaccg tttttcttaa
      601 acctgattat ttattttggt aatacaatgg gtcaaagctt tacttacgtc aatggaaata
      661 aaagggcaat gatttggagt agtagtaacc tgaataatct ctttacagag ttaggaacga
      721 aactgtcact tttttatcca ggtacttgga tagctacttt agtagtcttg gcattattac
      781 tatgtttaat tgttggaatt tatttaagtt ttgacaataa gaaaacttct atttttttag
      841 ttattttgat gataatggga ttttgttcaa ggttaattat gggattttct cccacagtat
      901 gggcttccgg aatgcggacg tactatatac tttatgttgt tatcgccatc ttagtactaa
      961 tggcagttaa agagctaatg aaaagcatga gtgtacaaaa aaatgaattt atgcaatttg
     1021 gattaaccgt gcttggtatt tgtaccttta taataacggt gataaacaga taatatacaa
     1081 aaaatccctc gctttagtat taggtgaggg attttactcg tttttcgatt aattgtttta
     1141 acacttgcaa gtttctacga gtagcttgtt tccgaccttc atatactcac ctcaggctgt
     1201 ttacatgatt gtacgttctt tttgtaaagg atacagtgat atgtatataa tggcataaag
     1261 aaacgttcaa acaaaaaaac tcgtgaagca aaattaactt cacgagttgt agtgcagatg
     1321 atgggactcg aacccacacg agctaacgct cacatgaccc tcaatcatgc ttgtctgcca
     1381 attccaacac atctgcgtaa taataacaca ctaatgatag cgaggtttta catagttgtc
     1441 aagctcaaaa atgggaggac ttattaagat ggagaaatat gacggagaat tttcaggact
     1501 gggaatgatc ttaggtgtat tgattggact tgcattcgga cgttttttgc ttggttttat
     1561 gctaggaatc atttgtggaa ttgcaatgga ttgggcagcg aatctatgga atgactatca
     1621 tgacaattaa gttctcaacg cttgtttgtg tttttttaat acttacgttt ttcctaaata
     1681 agtggcaaaa ttttctagga tggagtatga tattgaaata gtaaataaca aaaaatttgg
     1741 aaagttctaa ctttttgaaa tgagggattg gctaagtgat gagagaattt gaaaaatcca
     1801 acaaattaga aggtgtcagt tacgatgttc gcggtcccgt tctagaagaa gcggagcgga
     1861 tgcaagaaga gggcattagt attttaaaat tgaacacggg aaatcccgca ccttttggat
     1921 ttgaagcacc aaacgaagtc attcgtgatt tgatcatgaa tgcccgtgac tcagaaggct
     1981 actcagattc caaggggatc ttttctgcta gaaaagcaat tgagcaatat tgccaactga
     2041 aacattttcc gaatgtgacg atcaatgata tctacaccgg caacggagtg agcgaattga
     2101 tcacgatgtg tatgcagggg ttgctggaca atggagatga agtactggtt ccaatgccgg
     2161 actatccgtt gtggacggct tctattgcat tagctggagg cacacctgtt cattatattt
     2221 gcgatgaaga ggcagaatgg tatcctgata ttgatgatat caaatcaaaa ataacgagtc
     2281 ggacaaaagc tattgttatc attaatccta ataatcctac tggggcactt tatccaaaag
     2341 aattattaga agaaatcgtt gaagtagctc gacaaaataa cctgattatt tattccgacg
     2401 aaatctatga tcgcttagtg atggatggtc tagaacatat tccgattgct acattagcgc
     2461 ctgatttgtt cgttgttacg ctgaacggtc tatccaaatc tcatcgtgta gcaggatttc
     2521 gagtaggctg gatggtccta agtggagata agtcacacgt caaaggctat atagaagggc
     2581 tgaatatgtt gtcctccatg cgtttgtgtt ccaatgtatt gtctcagcaa attatccaaa
     2641 ccgcgctagg cggttatcaa agtgtcgatg agctgctcct gccaggcgga aggatctatg
     2701 aacaaagaga atatatctat aatgcaatca atgatattcc tggtctttca gccgtaaaac
     2761 caaaagctgc tttttatata ttcccaaaaa ttgatacaaa gcgattcaat attttggatg
     2821 atgaaaaatt cgttttggac tttttacatg aacatcatat tctacttgta catggtggtg
     2881 gatttaattg gaaccagcca gatcattttc gaatcgttta tcttcctaaa atggatgatt
     2941 tgaaacaaac agctaagaaa atgagagaat tcctagcaac ctatcgccaa aaatgatttt
     3001 aaaaaccaaa tttttcagta ggagggccac agacaaacac actgaggctc tctttctagt
     3061 ggagttttct taaataacta aagtatatta tttagttgca agtcttttct tgaagtttgc
     3121 gacttcctaa agtaaaatac gaatagaatg cgaatacgca tattttgggg aggatactta
     3181 tggaaacgtt aatcgagtcc tttggaacga tcattaaaga gattcgaaaa gaacaaaaaa
     3241 tgacgcaaaa aatgctttcg catgatattt gttcacaaag tgtattaagt cggatcgaaa
     3301 ataatgagga actgccgaat gtattggtga tgatgcagat ttgtcaacgg ctaggggtaa
     3361 cgattgatca tgtgatgaat ctctctcgaa aaactactcg gacaaacgat aaattatttg
     3421 aactgttgga tagttgtttc caaaaacgtg attatcggaa gttagaacaa gtactaaaat
     3481 cttctgatat ttctgaaaat ctgtatcaag caactgactt tcaacgctat tattattatc
     3541 tcggtgtttg cgaattcacg ttgcgtcaaa atatctctca gtccctttat tatttgaaag
     3601 aagcattaag ctactctagc caaaaagaaa gaatccatgt ttctgacaca gaaatacaac
     3661 tgattagttg tatcggaaaa atatatggtg tggcaggaaa aacggctgaa gcacgctact
     3721 atttgagtcg aagcatccaa ctgctgcatc aatcagctga tgaacgatca aaaagtgaat
     3781 tttcgcaaat tttttataat tatggaaatt tcttattcca tcaaaatgaa atcgacgaag
     3841 cgttagaaca ggtgaatcaa ggaatctatt gggctcaaga gaagaatagc tactattacc
     3901 tcaatgattt atttgtgctt aaaagcttaa tatacaagcg taaagaagaa ccagaaagag
     3961 cagcattcta tgaaggctta gcacaagctg tgaaacaaat ttcaaaaaat ttgtaaatgg
     4021 tgtagaccat tcttgacttc ttctctaaat aagagtactt tagaggtaga aaaacaaagg
     4081 gagagaatag aatgagaact tttatctatg ctgacaaatt ctttttagcg tcaggtgtca
     4141 aacatgcagg ctatcttgaa attaccgatg gactttttgg tgaatacacc aaagaactac
     4201 ctgagggaga agtcaacatc attgaccaaa gcggcaaatg gattgctcct ggtttggtag
     4261 atacacatat tcacggctat atgaatcatg atgtaatgga taatgatgca gaaggcatca
     4321 aagtgatgtc tgaaggtctg ttatcttgtg gagtgacttc atttttacca acaacattga
     4381 cgtcaagcaa agaacgttta aaagatgtag ctgagacaat cggcaaaatg tatcaggaag
     4441 caccaggagc taaaatcaaa ggaatctatt ttgaaggtcc tttcttcaca gaagaacaca
     4501 aaggggcaca aaacccaagt tatttcgggg atcctgattt ggatactttc catgaatggc
     4561 aagaagcttc aggtggttta atcaaaaaaa ttgctttagc accggaacgt caaggtgtag
     4621 aagagtttgt caaacaagtg actgaagaag gagtagttgt ttctctagga cacagtaatg
     4681 ctacactaga agaagcgcaa aaagctgttg aagcaggcgc aagtgtattt gtccatgctt
     4741 tcaatggtat gcgtggattg aatcatcgcg aaccaggtat ggtgggtgcg ttattatctt
     4801 tagaacatgt cttttctgaa ttgatttgtg atggccatca tgtacatcca aatgctgcgg
     4861 gaatcctaat ggaaaaagca ggacatgatc atgtcgcatt aattacagac tgtatgatgg
     4921 ccggtgggat gcctgatgga aattacaatt taggcgaatt tccagtagta gtaaaagaag
     4981 gaacagcacg tctagaatct ggcaacttag ctggaagtat attgaaattg aaagaagcaa
     5041 ttaaaaatgt tgtagactgg ggattagcaa caccagaaca agcagtcatg atggctagtc
     5101 tgattccagc aatcagctgt aaaatcgatg atacatgtgg aaaaatcgct caaggacgcg
     5161 atgcagactt tatcgtattg aaccctgata tgacattgga agcaacttat ctagatggcg
     5221 tggaacgttt ccacgcataa tataatttaa gttaacctta aaactaaact tcttaagttt
     5281 ggttttaagg ttttttttgt gttctagtaa aaatcacttt acataagttt caaaagtttc
     5341 tttaatttcc tattgttcaa taagtaacaa tgtaaagata aaattaaaaa tgttaatacg
     5401 tattagcaaa ataaaagctt tttttattgt gaataaatga acataattag gaggagaaag
     5461 atgaacttat ttgacatttt tcgatcgact ttgacagata tgtcgattgt cagtgcaatc
     5521 acttcaacag tttttattat attattaggg tttgtttgta gaaaaaaggg gattttttct
     5581 gaatctgttg gaaaaattct atcgaaagtc gtcttaacag tggctttgcc agcactggca
     5641 tttcgagctt tcatgcaaga tatcaataca gaattactga tgcaaggaat caatgtcttg
     5701 atttggggat tagttattta tattattctt attctagttt caaaaccttt tttcttaagc
     5761 tataaagggg ataagcaaac aacgttgcgt gtcctgacga tctttggttc tacgaccttt
     5821 ttcggaacgc ctatcgtcag tgcgatttat ggtcctgtcg gcgtgatgta ttcctcaatt
     5881 ttcaatattg gctaccgaat ctttttgtat tcttatggat acataaaaat gagtggcttg
     5941 aagatggaag ctaaaaatat caaagcgatg ttcgtcaatc caatcattat cgctactttt
     6001 gccggccttt tcatttggct gttccaaggg tatctgccac aagtgtcagt tacaggtgca
     6061 gaaggagaga taagccaagt agcgtttttg cgaattgacc agactgcacc gtggctattt
     6121 cagccgatgg attatttagc tggtttaagt tcaccattgg cgtggctagc aatcggcgca
     6181 acattaggtg aagtaagctt caaaaaagct gcatctgaaa aaacttcatg gtattacagt
     6241 ctagtcaaag tggtatttgt acctgcattg aatatcgtga ttctagcagt tttgacggca
     6301 acgaatattc taccagtcaa ttttgaagca ctggcaacaa tcgttatcat gatggctaca
     6361 ccagctgcaa cagtggcagc agcctatgct atcagttttg atagggaggc acttttagcc
     6421 tccaatgcat ccttactgtc aactattttt gctgtggtac tgacacctgt atggatcgtt
     6481 gtattacaaa tgattcatgg cataggttta ttttcataag aaatggagga agaaagtatg
     6541 agaatcgcat gttacggtgt tcgtccgaac gagatagatt tttttgaaaa attgaatatt
     6601 taccattatg atctcagtct ttatgaagaa ctgttgacac atgacaatat cgtgtcagca
     6661 aaggaccatg atgctgtatt gttgagggga aattgtatag cagatgagac caatcttgca
     6721 aaaatgcagg aatatgggat tcgttatgtt tttacacgga ctgtgggagt caatcatatc
     6781 gatctacaag cggcagctga ttttggtatg acagtagccc gtgtaccatc gtattcgcca
     6841 aatgcgatag cagagttatc tttgactttt gccatgatgc ttttgagaaa tactgcgtat
     6901 acgacgatcc gaacatcttt caaagatttt cgagtggatg agcaaatgtt tagtcgtgaa
     6961 atcagaaatt gcacagtagg gatcatagga acaggcagga tagggttgac ggaagctgtt
     7021 ttgtttaagg gactaggagc caaagtgatc ggctacgata ttcatcagac agaagctgct
     7081 aaaaaagtat tgacgttcca ctcgcttgaa gagttattag ccaaaagcga tattgtcagt
     7141 attcatgtac ctcatatccc aggtgaaaac gatcaaatga tcaatgaagg atttttagct
     7201 caaatgaaaa aaggtagcat cttgattaat acagcccgtg gagagcttca agataatgaa
     7261 gctattttaa gagctttgaa aagcaatcat ttagctggtt ttgcaaccga tgtttttgca
     7321 aatgaaacag aggttttttt ccgatccttc aagccatggg agacgattcc agaccctgct
     7381 atccagcaat tagtagaaat gtaccctaga gttcttgtaa ccccgcatgt aggttcaaat
     7441 acagatgagg cattatcaaa tatgatttcg acaagtttcg agaactttcg tgaaataata
     7501 gaaactggaa aaacgaaaaa tgaggtatct cttcctaaag cccgtcaatt aagataagaa
     7561 aacatggata ttcgtcaata aaatgtttaa aaatagtcca agtaaacagt tgttacttct
     7621 gtatacttgg actattttgt atgggataat tcgatgactc aacagtaatc tgtgagcttt
     7681 ttccgcccat tctttgtcaa ttcataacag gttagcggcc ggccgatttc caaatatttg
     7741 attctttcgt tcaatatatc ttgttctact aaaaaattca aatatttctt gacggatata
     7801 cgtgacagtg agcttttttg agccagttct tttgttgaaa aaatagtatc ttcttttaga
     7861 ataaatgcac ttattttttt taaagtcagt tttgacagac ctttaggcaa atcgatgaat
     7921 gatggtattt cgtgaatggg agtggtgtgg ttgaatactt gatcgatcaa tttctgatcg
     7981 gctttttcag tcgtttggat tgtctgagag aaagcaagat acttttcgat cgccagctga
     8041 aaacgttgca aagtgaacgg tttgatcaaa taatctaagg caccgtagcg gatcacattc
     8101 tttatggttt cgatatcatc tgcagcagtg atcaaaatca ctgggatatc atttccttgc
     8161 tgtctaagcc aagataaaaa atggatacca ctttcgccag gcatgtatac atcaagcagc
     8221 agcagatctg cgtttttttg tctgaaatat ttttttcctt cttctacatt tctgaaactt
     8281 tcgattacgt tcatattagg gatgctttcc acaaaagtac gattcaattc tgcaaccatt
     8341 ggatcatctt cgattatcag gacatttgtc atcattttga tcttcctttt ttggtaattc
     8401 tagatagacg attgtaccgc catttgtttg tttggaaaat tctaaaaatc caccgtggcg
     8461 tttgacgatt gaatggatga gattcaatcc aaacccacga ttgattccct tcgtcgaaaa
     8521 acctagcgta aatatttttt ctgagatttc ttctgatatc ccgacaccgt catcgcagac
     8581 ggtcacgatg aatacttcag cttctgtgtc atagtttaaa tgaatccgga cctgtccgtt
     8641 tctttcatgt ttttgtagca cggcttcttt tgcattatca agtaagttcc ctaacacttg
     8701 caaaagtgaa tggatggagt catccatctc cattttaggg ataaaagaat cgctttctaa
     8761 cagcatttca acagattgtt ctttggcttc gtttattttg cctaataaaa aaccggcaat
     8821 tgcaggtact ttgatcagac ttgagacttg gccaatctct tttttataat tttgatttag
     8881 ctgctggata aaatgggtga cttcttcata cttcttcaaa tcaatcaaac cagaaatgac
     8941 atgaagttta ttcatgaatt catgggtttg agctctcatg gagtttatat attgtttcgt
     9001 ccccccaagc tcctccatta atttcattac ttctgatcga tttcgtaaag ttgcgactgc
     9061 tcctaaaaaa cggtcattgc taaaaagagg tgtaacgcta gaaatagttt ctatcccatt
     9121 taaatacatg gattgagtcc gaacggtcgt ttgatgctca atcgtctctt taaacaaaac
     9181 gtcatataga ttatcactga tttttttcct acttcgaaat ccaatagctg ctctgtttgg
     9241 tagaaaatgt tttttgcagg tgtattgatc aagaggatag ttttatcaga agagatggct
     9301 aagattcctt catctacttc attttcgata atcgtttttt cacttaactg ttctgctatt
     9361 tcttgtggtt caagtccaag cagtactttt ttcatttttt gggcaagaaa aacggcgcct
     9421 atgatgccta cgctaagtcc aataatcaat gaaaaaacaa tcattttttg tccatctttg
     9481 acttgattgt caatcgtgtt gtttgttaag ccaacacaaa ctgcaccaat aatctcttga
     9541 tcataataaa tagggacgaa atagcggaag ccgaacccta acattccttc tttttcagag
     9601 aaaaattctt gtcctccaat cacttttttc acatcttcat gacttgagaa aggaagaccg
     9661 atgtaacttg ggtctgcgtg agaatatcga atgccttcag ggtccatgac aacgataaaa
     9721 tctaaattcg atgcaatcat gatttcattt gttattcctt gaatcgcatg tgtcgggtca
     9781 ccagtctgca gctttttttg gatgagttta tcattggcaa cgattttagc aatgctagag
     9841 attttatctg acacactaga tcggttcatc gaaagaataa aattcctgat caatatggca
     9901 gaaacaatca aagaaacgaa tgtggagaaa caaacgacaa ggatgatcgt gttctggagc
     9961 tttaatggtt ttttcttaaa aaaaggaaac ataggctacc tcgaaagaat ttattgtgaa
    10021 aattttaaca tgaaaacaaa aatttaacaa attgtcaacg ataaacacaa ccttcctata
    10081 aaaaacacca ctgagtcggt aaaagaagct atacagaatt ttcaaacatt ggtatgatag
    10141 acgtagaaat ggaaggaggc gtgtatatga tagggggaat cgcacttgag acgatttatt
    10201 ggtatacatt gctgatttgt gcaggattgg cagtcctatt gattattttt ggagatgtat
    10261 tcgattttga tggcccgctt gatccgatgc ttattatccc ttggttaact ttcacaagct
    10321 tatttggttt tctaggtgag cgtttaacag atcaatcatc tttattttta tttattgcta
    10381 gtggaggcat atcgatagtg ttggtatttt tgcttaattt ctatatattg atgccgatga
    10441 aacatgccga atcaacgatg tcgtcttctg aaaaaactct ggaaggacaa gtagctgttg
    10501 tgatcacacc gatccctgta cgaggtatgg gagaaattca gttgaaaagt gttaccggtt
    10561 ccattagtcg tccagcttgt ttttacagcc cccaagaaca gacagctgag cggggaacga
    10621 aagtattgat cattgagatc aaggaaagaa tctgttatgt catgccttat gaaagcatga
    10681 taaaagctta aaggagcgtg tgttaaatgg aaataccagt tgtttttatc gcgatcgcaa
    10741 tcgcagcttt gattttactg atgttgctga tcgtctttgt agcgaagtac cagacagcaa
    10801 aaccggatga agcgttgatc atcagtggaa gttatttagg aagcaaaaat gtgcacattg
    10861 atgaaagcaa taacaaaatc aaaattgtgc gtggaggtgg cgcattcgtc ttgccagttt
    10921 ttcaacgttc gaatcggatc agtctattat cgagtaaatt ggacgtctcc acccctgaag
    10981 tgtatacgga acaaggcgta ccggtgatgt gtgatggtac ttcgatcatc aaaatcggtt
    11041 catctgtaga agagattgct acagcagcag aacagttttt aggcaagaca agagaagaac
    11101 tggaaaatga agcaagagaa gtattagaag gacacttgcg ctcgattctt ggttctatga
    11161 ctgtagaaga aatctatcaa aatcgcgata agttcagtca aagcgtacaa gaagtcgctt
    11221 ctgtagacct tgcaaaaatg gggttgatca tcgtttcttt cactatcaaa gaggtcagag
    11281 acaaaaacgg ttatcttgac tctttaggga aaccaagaat cgcccaagtc aaaagagatg
    11341 cagatatagc agaagcggaa gctctaaaag aaacgcgtat caaaaaagct caagcagaaa
    11401 aagaatcaca agcagctgaa ttacagcgac aaacagagat cgcagaatca ttaaaagaaa
    11461 aagaactgaa attagcaacc tacaaacaag aacaagatgt tgctaaagca aaagcagacc
    11521 aagcctacaa tttagaaagt gcccgagcac aacaacaagt aatcgaacag gaaatgcaga
    11581 ttaaaatcgt agaacgtcaa aaacaaatcg aactggaaga aaaagaaatc acacgtcgtg
    11641 aaaagcaata tgattcggaa gtgaagaaaa aagcagatgc cgatcggtac gctaaagaac
    11701 aagaagcaca agctcaaaaa gtcaaagaag tgactgaagc cgaagcagaa cgattccgtg
    11761 tggaagcact ggcagaagcg gaagccaata agacacgttt agctggacaa gcagaagccg
    11821 aagcagcact agcaaaagga aaagcagaag ccgaagcaaa acaaaagatc gccaatgcct
    11881 tcaaggaata tggcgaagca gctgtcttga gtatggttat cgatatgcta ccgcaattga
    11941 tgcgcgaagc agcacagccg ctaggaaata tcgaaaaaat ctctgttgtc gatacaggaa
    12001 gcagttcagg agaaaccagt ggagcgaacc gagtgacaaa ttatgccaca aatttgcttt
    12061 cttctactca agaaacacta aaagcgacaa caggacttga cttgaaggaa atcgtagaga
    12121 atttgtcgac acgtgggact actagccaag taaatatgta tgaagcgcca aaagaggcag
    12181 aacaaaactc gatgaaggaa gaataaagta gtacacttca ccgttcaatc aaaaatggag
    12241 gaagactttt taaagttctt ctctccattt ttttatttta ttgcaaaaga aaattagtcc
    12301 tcgctatttt tcttttgttt ttggatctta gcttctatct cttgtaaatt tgttcttagc
    12361 aatcgttctt tcttttggag ttcgaccaaa tcttctgata gttcttcctt cttttctgtt
    12421 tcaggaggac gaagaaagaa attgataccg attgcaatga atgtccctat aaaagtatct
    12481 agtacacgtt ggatagcata caaagcggat tcgccttgag ggatgctcaa cgcaatcagc
    12541 aacaacgtag ctattgcgga aatgataccg gaattattgt taataccatc tgacacgacg
    12601 atcacaataa taactagaat aggaagcaag atcaattcta ccaaaaaatc attgtgaaaa
    12661 tagcttttga caaaaaaata aatgatagct aatgtaccac ctaatgtatt gccgatgatc
    12721 ctagactttc caaaagaaac ggttgtagtc aagtcctgac gcaaagaaaa aacagcagat
    12781 aatgcagcaa tcatcgggat tcctcgttga gtcaaatgaa aaaacaagat acataaaaaa
    12841 acagctaagg cacttttgat cgtacgcata cctagtcgaa aacggccaaa ttgcatagag
    12901 attctccttt ttggtctttt tactatcata cctaaacttt tgtctgatag ctagtttttc
    12961 attattcaag tataattaaa ataaaaaagg gggaagtaaa tgcgtatagg aatgcgaaca
    13021 gtcaaaacag tgatcagtgt cttcttttcg atggtcacag cgggtagctt atcgctgttg
    13081 tattggccag ctgcagggat cattgcatta ttaagtgtag gaaataccaa gcgctctaca
    13141 ttgcgtacgg gcatgaatcg aatcgcagcc tttatattag ctacggcaac agcactgttc
    13201 agtttttttg ctgttgggta tactattttt ggcttcagtc tttttttatt cctgttcatc
    13261 ccgcttgcct ctcgcttcaa attaaccgaa gggatagtag taaattcggt tttggtcact
    13321 cattatttag tggaggaaaa catgtcttgg cagctgatcg gcaatgaagc gggattaatg
    13381 gcgattggat tagtatttgc tttgcttgca aatgtttaca tgccagatcg tacgaagcag
    13441 ctgaaggaaa accaaataca gatcgaaaaa gaatttcgaa atattttgag acaaatggca
    13501 gaatttcttt tatcagaaaa taaagaagat gtgcagatca aatgcgaaca tttactgaca
    13561 ttcattcgcg aaagccaaga agatgccaga gaacatcaag aaaactactg gctcagacag
    13621 ccgctatact acgaaactta cttctctatg agaagagcac aggccaatgt gattaaagac
    13681 atgctggaaa atctagagag aatccagcaa ccagcttatt atggaaaaca tatctatggt
    13741 ttattgattt atactgcaga aacattttca gagtcaaatg atggcagaca aattttaaca
    13801 cgtattgaag aagtttatgt attgtatcgg caaatgcctc tgccgactag tcgccctgaa
    13861 ttcgaggatc gagcagaatt gttccagttt ttgcagtctt ttaaaagttt tattgaaatc
    13921 aaggcagaat tctcccaaca aaaaatccaa aaatagaggt tgtgaattca gctaatattc
    13981 aggtcaaaaa gctgatttca caacctcttc tttaaacggt gttctcctgt caactcctcg
    14041 gtcacaagtc acaatattca acaaacatga gaagctgttt tttgaaattg ctccttgtga
    14101 ctcggagctg aacggtaggc tcacaacctc tttcttaaac ggtgttcaaa agctttcctc
    14161 tgcggtaata agtccagcca aacgaaaaat aggaggagct atttttgttt ggctgttctt
    14221 attacttgat gcagaacagc tttttcacaa ccttttaaaa ttacatattt ttccatagaa
    14281 cttgcatttg atccaagatt tcgatgacat cttttgtcaa gaagagagag cgattgggca
    14341 agtcaccttc aatcatgtgt accatattct ttatttcgta attcattgct tcagatgtat
    14401 tcccgctttc gatgaattcc tttgtaccat ctgtaaataa gatctccgca cgatcagcac
    14461 gcgggtaatc agcaatcgtc acataaccgt tctcaaaggc aacgataccg acttttggca
    14521 tttttgcctg aaaagtcaag ctgacagcag caagttcatt ttctttgtta cgcaagatag
    14581 tgacggattg ttcgtccacg cctgtttcaa aaggaaccat tgtagaggca actacttcag
    14641 gttgagagct caaaaagaaa cgagcgaaag atacagcata cgtaccgata tccaacagag
    14701 ctcctccagc taattctgga ttgaagaacc ggtttttagg gtctggttct ttgtaactgc
    14761 cgaaaggtgc ttggatcatt tttaaagccc ccagttttcc tgtatccatt attgagcgta
    14821 actgctgata aagtggcatg ttgaagattg tcatcgcttc tgctaagatc aaattctttt
    14881 cttctgctaa gcgcatagcg tcagccagtt cttttttatt catcgtgatg gctttttcac
    14941 atagaacgtg tttgcctgct tccaatgctg ccaagatatg gtcgatatgc tgtctatttg
    15001 gtacagcaat gtacacgatg tcgatttcag catcgtctaa catttcttga tagcttccgt
    15061 aagcttttgg aatattgtaa cggtgagcga agttttccgc tttttctgaa gttctggaag
    15121 caactgctgt tagttcgctc gtctcttgat tgaagctttc ggcaaactca tgtgcgatgg
    15181 taccaagacc aacgattccc cattgatatt ttttcatctg aaaacgctcc ttcatagttg
    15241 gattgagttt cttgtctgtc tattattata acaaaaatca cgaagaataa agaggagagg
    15301 acttgaaaca ttaaaaaaaa tgaaagcagc gatttaagag gtgctttttg atcaaaactt
    15361 aagtagaata gttaaaagga ggggataaac gtgcatcaag tatatattga tcttattatg
    15421 agtgtattat tagaacagtt tgaaactgaa aaaaattttt tagatgaata cttgctgatc
    15481 agtccagaac aatggcaaaa atggaaagat ggcgagaaaa atctgccatc tgaagcgatg
    15541 cagaaagtaa aaaatctttt cactgattat gaatggatgc taacgcaaaa gattttgcgt
    15601 caaacgatta tttttcccga aaaacgaaac gttgccgttg cagagtacaa gcaaatcaaa
    15661 acacgcatcg cgcaaaaatg gcttagcagc aaagcagcaa aagtcgagct gatccctttg
    15721 aaaaataatc agcaggctgg tagatacctt gacttgaaag taagtattca atatgatgaa
    15781 tggggctatg atgatatttt gaattttcgt ctgccagcag atgttcaaaa acagatcgaa
    15841 ggagaaaaaa tcgaacttct cgattgggtg aatgaaaatc tggaagaaac ttacgttcat
    15901 gaggcgaatg gggaacgtga agaacaacga aaggattttt caagtgaata aatttttagg
    15961 atttggagca gttgtgatta tgatcgcagc aatgggctat gttattttta gcgatgatga
    16021 ttcgcatgtt caagccggca atcaagcagt cgaacgaaca agcaccaaaa caactgctag
    16081 taaagaaaag aacagtcaaa caaccagcag caaggtaaag gacaaagaaa caaaagatcg
    16141 tacgtccaaa caattgccag atgttaaaac agacgattgg aagctagttt tggttggtcc
    16201 agatcacaaa ttagaaaaag aaattgatga gtctactcaa ttggcatcat taagtaacgg
    16261 atacttgatc gacaaacgca ttgctccaga atatgaagca tttgccaagg ctgctgaagc
    16321 agctggattt ccattagtga tggtctcagc ttaccggtct gtatcatccc aacaacaagt
    16381 tttcgaacaa aatgtccaag atgtgatgag tcgtcaaggt gtatcagaag aggaggcgac
    16441 aaagattact aaagaaacga ttacggagcc aggatacagc gaacaccaca caggtctggc
    16501 agtcgatgtc gtcgatcaaa actggtacaa cagttatcct tctactgtat tggatgcaag
    16561 ttacggagat cagcctggag ctaaatggat cgcagataat gctgcgcagt atggatttat
    16621 cgttcgttat ccaaaaggac acgaagatat aactaagatc acatatgaac cttggcactt
    16681 acgttatgtc ggtaaagaaa acgctgagta tatcaccaaa caccaattga cgctagaaga
    16741 atatctgaat gaattaaatg aaaagtagga attgatcatg gcgaaaaaaa agtggaaaaa
    16801 gcaaaagcgc aagaatatcc gttggccagc agtggttgcc ggtgtagcag tgatactctt
    16861 agcctttgtt ttttccttga agaatctgtc ttctcctttt actgataatc agcaagaaaa
    16921 tgaagcgcaa tcccatcagc aatttattga acggcttgtt ccgcatgccc aagaactaca
    16981 agatggttat ggagtgcttc ctagtatcat tttaggacaa gctatattag aatcaaattg
    17041 gggaaaaagt accttggcta gcaaatacaa taatcttttc gggatcaagg cttatgggga
    17101 tcagaagaaa gtaagcctgg aaacaaagga atttgttaac gaagaatgga taactatcca
    17161 aggagacttc aaagtgtatg attcatggga acagtccatg gatgaccata cacaactgtt
    17221 cgtccaagga gtagattgga atcctgcgct gtatgaaaaa gtgattacgg ccaccaacta
    17281 tcaggaagcc gcacaagcat tgcaagatgc aggttatgcg acagaccccg gttatgcgca
    17341 aaaaatcatc caggtcatcg agacgtatca attgaatcag tatgaccgga gatagcaaag
    17401 gagaagtggc tgatggcaga acaatttacg ccagaaatca tgacggaatt gagaaaagat
    17461 atcgtaagag taccggaaat cattttagaa gcaagcggga tcaagatatt tggaaaattg
    17521 atccgttcga tcatctttac tacggatatt gcgatcatac gtaatacaaa tgcgaatgca
    17581 gtaattgctg tgtatccttt tacacctcat ccagcgatta ctaaaagcat tattgaggca
    17641 gctgacattc cagttttctc cggtgtaggt ggtggtttga cacaaggtgc tcgttcttcc
    17701 tacatgagca tgttcgcaga agcgcaaggt tcgttagggg tcgttttgaa cggtcctacg
    17761 cctttagaga cagtaaaaga agtttgtcga gtagttgata ttccagttat cagtacggta
    17821 acgtcgaaat atacagaaat agatgaaaag ttagcagctg gtatttcgat tatcaatatc
    17881 agtgcaggta aagaaactgc agaagcagta cgccattttc gtaaaaaata tcctgaactt
    17941 cctatcattg cgacaggtgg tccaacggaa gaaagtattg ctgagaccat tcaagcagga
    18001 gcaaatgcca tcacatatac gccaccaagt agcggagagc tttttagtcg taaaatggaa
    18061 aaatatcggg aaactgagaa aaagaatcat gaataacagg tgagaatcaa aagacgagga
    18121 agagcagata gtggctcttc ctcgtctttt gtactccagt actatttgtt cagaattcaa
    18181 aaaaaagaga aatttttttg tttttttacc tgtaatgtac ataagaagag ttaaaacctt
    18241 ttgttattat tagcattcta acaaaaaaat gtcttgattt attgaagcgc tttctataga
    18301 atgaaaaacg aataaaaact aaaaaaggca cccgacaatt tagtagcagc taaattgtcg
    18361 gggcttgaaa agtcagcggg aactgaccaa tcaagttgcc atagtcaatg cttgtgcatc
    18421 gacgtgtata ttgtacctaa tttcatacag aattactagt tatttttctg ttttttaggg
    18481 aagagcgcac acgaagaagc atgcttattt agctatgtca aggatattgg gcagttgtct
    18541 gatatccttt tttctttgcg taattatcct cccatcattg aagcaagaag tgtttttagc
    18601 gatgaaagaa gaatcagcac tatctaattt ttcttgaaag tattgagttg ttcatcctag
    18661 gcagaacgat aaggcaagtc ttggttttta ttccccttga aaaagatcgt ttaataaata
    18721 tgttctgtat aaaaatacag tatattgaaa aataacaatg gaagtagagg tgcagagaat
    18781 gaagaaaaga atgagaatca tcttagcttt aagtgttatg ttattcttct tgacggcttg
    18841 tgggcaagaa gatgacaaaa aaatcacgct gaacatggct tggtggggtt cgcaagtccg
    18901 acacgatgca acagtaaaag taatcgagct ttatgaagaa aaaaatcccc atgtgacgat
    18961 cgattatgaa ttttatgatt atgaaggata ttacacaaaa ttaggtacac tagcagcatc
    19021 agatgatatc tgggacattt tccaactgaa caatcaattt cctcaataca tcaatcagat
    19081 tgaaccatta gatgaatatg tggagcaagg gataattgat atttctaatg cagatgaatc
    19141 ctatttagca acgacgactt acgacgggca attagttgga ctgtctaacg gggtgaattc
    19201 gtttgcgatt gcttacaata aaaatatatt tgaacaatta aatatccctg aaccagcttc
    19261 aaattggaca tgggatgaat ttgaacaaat cagctatcaa atcactgaag aattaggaat
    19321 ctatgctatt tcaagattcg aagattttat agctggctgt attattcaaa taccacaagt
    19381 tgagaaagga ttgaattttt ataatcggga agatctatct aacagcttgg gatttgaaaa
    19441 tccagactat ctaacagatt ttttccagct gcgtaaaaat ctggtagaca aaggggccca
    19501 tccagaacca ggtggtggag ctgcaagtac gacggatctg tcttttcagg cggttaggga
    19561 tagagaagcg gcaatggtgt ttctatcaag taaccagttg acagaaatat tgtcaggggc
    19621 tcctgaagat atggagattc agttgattaa tccacctcgc agaaaagcag atggagaatc
    19681 tggtatccct ttacgttctt cgcaaatgct gagtatggca aaaagctcag cccataaaga
    19741 agaagctgct aagtttattg atttctttca aaacagtgaa gaagccaatg aaattttaaa
    19801 aggagaacgt ggtgtaccaa tcatgtcgaa tattcgagaa cagctcgctc gtgcagatga
    19861 tgcaactttg caagcgacat ttgattattt agaaatgatt tccgatatgg acaacggcga
    19921 agtgaatgtc tttgatagtg ctttgaatcc ggaaattcaa gaccaataca atcttttagt
    19981 tgaaaaagtc atttatgaag aagtaacagc agaagaagca gcagagagtc tttatgagtt
    20041 tgcgtcaaac attctaggat agcagcagga ggaaggcatg aaaaaagaaa aactaaaacg
    20101 gttcttggat caagacaatg tggtcggtta cgtatttgct tctccattca tcctaggatt
    20161 tctattgata acagtgatac cgatgatctt gtcactttat tattcgttca ccgattatcg
    20221 tttgggaaat ccagtctcat ggatcggctt ggataattat ataaagatgc tgagtgatgc
    20281 ccgttttttg aactccatcc gagtcacttt tctctatgta tttgcatctg tacctgtgaa
    20341 actgatcttt ggtctattga ttgcttatct tttaacgagg aatatcaaag gaacgacttt
    20401 ctttcgttct ttgtattatg tgcctagttt gatcggtggc agtatttcta tcgctctagt
    20461 ttggcgggag ttgttttcta aaaacgggtt agtgaatatt ttcctggaac gattaggcgc
    20521 acctgcgctt tcctggttta gcgatcaaaa actggtcatg atccctcttg ttttgatgtc
    20581 tgcttggcaa ttcggttcgg caatgatcat ctttgctgca ggtatcaaag agatcccagg
    20641 ctcgtattat gaagcggcag agatcgatgg agcgaacaaa tggcagacgt tttacaagat
    20701 cacgttacct cttctttcgc cgatcatttt gtataacttg gttatgcaga caatcgcggc
    20761 gtttatgact tttacgcagg catttatcat tacccaaggt ggtccgaatg atgccacgaa
    20821 cttttatgct ctttatgtgt ataaccaagc tttttctttt aattctatgg ggtatgctag
    20881 tgctatttcg tggatcatgc tgttgattat gggagctgtc acctttctga ttttcaaatc
    20941 atcaaaaaaa tgggtcgttg tgtgaatgag aggaggaaga aatgaataat acagtaacga
    21001 aatggtttca atacggtttt attttgctat taggtctagt catgatttat ccggtcttat
    21061 ggatgatcgc aggttctttt aaaacggatc aagagattat gagtggttcg ctgaatttga
    21121 ttccagagac ttttcaatgg gaaaattacg caaaaggatg ggcggggttt gctggaattt
    21181 cattttttac tttctttagg aattcgtttg tcatctctgc agtttcgacg atagggacag
    21241 ttctgagctc gacttgtatt gcttacgcat tatcgagaat cgatttcaaa ggaaaaagat
    21301 tctggttcgt cgtcatgtta gtaacgatga tgattcctgc acaagtgatt ttgattccgc
    21361 agtttattat ttacaatcgg ctgaatttgg ttgggacgta tgtgccgctg attttaccac
    21421 atttttttgg acaagcattt ttcatttacc agatcatgca attcatggtc agcatcccca
    21481 aagagttaga tgaatcagcg attattgacg gatgcagcaa gtatagtgtc tttaccaaaa
    21541 ttatttttcc tttgctgaaa ccttcgatca tcacgacgat catcatccag ttttattgga
    21601 aatgggacga cttcatggga ccattgattt atttaaacaa gccgagatct tacacggtat
    21661 cgattgccat caaattattt gcagacgctg gatctagtac gacttacgcg agtatgtttg
    21721 cgatgtctac gttgtcgctg ctaccggttt ttctgatttt cttattcttc aataaatatc
    21781 ttgtccaggg gatcagtaca agcggtctga agggctgaat atgaaaaagc caatagaaga
    21841 gatgtttctt tacaagctca actactatgt ctgtcggatt tttttaacca gtcttatcag
    21901 taatgctctt ttcgctttag ttctaggatg tttgttcact ttaggattag tgctgtctgc
    21961 tcgtgttgtc tatctgattt attttttgat gatgtatcct tcttattatc tatctgtcca
    22021 ttacttggca gaaaaaaagg tatgttggag gaaaggaaaa atcaaacgga tgtgtttcat
    22081 cattacgttg tttcagctgt ttgtcattat ttttgcagtt gattggtatt tattagtggg
    22141 aaagattgga gcttggtatc tgattccttt tctattgtgt ctgttgcttt ttgtatccca
    22201 tagttttttt agtacgctaa ttgatatctg caaagaagat aaagcagata gtcttgttta
    22261 tttgatcaaa aggaatatct ggctgttgtc aaaaaacgtc aaggggtttc tgtggtattt
    22321 atgccttttg tatggactgt tctggtgtat acagcatgat tttttactca ctgcattact
    22381 gtatccaggg ctgccatttg tcacagtatt ttgcttaaaa gaaaaggaga atgactttaa
    22441 atgaagaaaa aatatgtaca agtcggactt ggtgggagag cgcgtttttt ttatgaggca
    22501 attgcctcta cgtatcatca aacttgtgaa ctagtcggtt tttgtgatgt atctcaaaca
    22561 aggatggatt atgcaaatcg gatacttgtg aacaagtatg gacagaaaaa agtaaagaca
    22621 tgtatgccat cacaatttga gcaactactg gatgacgtac ggccggctga agtcattatt
    22681 acgtcagtag atcgaacgca tcatgattat atcattcgtg caatgaaaaa aggatatgat
    22741 gttatttgcg aaaaacctct gactatcgat gaggaaaaag ctcaagaaat aataacggtc
    22801 caaaaacaga cgggaagaag cctgcgagtc acttttaatt atcgttatgc accgtatcac
    22861 acgaagataa aggaactgat agaaagtgat gtgattggtg atgtgttttc tatccacttc
    22921 gaatggctgt taaatacgca acacggggca gattatttca gaagatggca tcgaaataag
    22981 cacaatagcg gcgggcttct tgttcataaa tctacccatc attttgatct agtgaatttt
    23041 tggttgaaca gccgtcccca aaaggtattt gcattcggtg gattaaactt ttatgggatg
    23101 cataatgcgg agaaacgcgg agtagaaata ttttacagtc gatgctatgg aagcgaacta
    23161 gctaaagctg atccatttgc tatagacctg tcagccaatg aggaattgcg agaaatgtat
    23221 ttagaagcag aaaaagacag tggatatatt cgtgaccgca gtgtattttc cgatgatatc
    23281 tctattgaag atacactagg cgtaacggtc aaatatgaaa ctggtgcgat tttgacgtat
    23341 tcgctaaacg cgtatatgcc gtgggaagga ttcaatgttt ctttcaatgg cagcaaagga
    23401 cggatcgaaa tgaaagtgat cgaaaagtct tacatcaatg caggtggaga taaaaaggat
    23461 gaaggagcag ccgttcttca gtccatccat gtctatccga tgttcggtga gccatatgag
    23521 gtaatcgtcg aacaagaagc gggcggacat ggcggaggag atccgcgttt attagatgat
    23581 ctatttggtg aagaaaaaga agaagatccg tggaatcggg cagcaactca cgtagatggt
    23641 attttgtcga ttttgacagg aatcgcagca aatcattcta ttgcttcagg aaaagcagta
    23701 gtgattgacg agcttgtcag cttaaaagaa taagaataga tttacggaaa ttacttcccg
    23761 tagtttataa aatcttgcct tattgccgat aggctgtctt ttgaacacta tttattcgga
    23821 aaaaggggct atgacatgct ttttgtcatg ccttcttttt atgtgggctg cttttttaga
    23881 taggagaaaa taaaaataac tatttaaacc cgaacaaaaa ggaataatgc attaaaaatc
    23941 attagatttt acaaaaaaat aagtaaacca cgttgtcagt ttcagaaagt agtgttagac
    24001 tgttttcaat atttgaaaca acatttttta ttcaaatatg gcaaactgcc ttcacgtgca
    24061 aaacagttgc aagaaaatga atttacacta ttattagttt tacataccta cttatatatc
    24121 gtcataatat ggatgacagt ttctagccag taccgtaaat gctggactat aagtaaaaga
    24181 ttggctattt cacccttctt ttcttatgat aaagtggagg gtgtttttct ttaacagaaa
    24241 catagtaggt ttttgcacaa aagcggttat ttcggtatta ataaatgata aaggagcaaa
    24301 taaagtgaaa gaattagttg aacgtattca aaaagacgga cgtatattag gcgagggcgt
    24361 attaaaagtc gacagcttcg tcactcacca agtagaccct gtattgatgg aacaaatggg
    24421 aaaacggttt gcagaagtat ttaaagaaca aggaatcacg aaagttgtga ccattgaagc
    24481 ttctgggatc gcaccagctt tatttgctgc aagagaatta gatgttccaa tgatcttcgc
    24541 tagaaaagca aaaagtttga cgatggatga agaattattg acagcttctg tttattcttt
    24601 tacgaaacaa gtgacaagta cgatttctat ttctcgtaaa tttttatctt cagaagacaa
    24661 agtattgatt atcgacgatt tcttggcaaa cggacaagcg gcaaaaggat tgatcgaatt
    24721 atgccagcaa gctggagcgc aagtagaagg aatcgggatc gtcatcgaaa agtctttcca
    24781 agatggacgt cagttacttg aagaaatggg attgagagtc gtttctcttg cgcgtattgc
    24841 ttccttgacg aatggacaag ttgagtttct tgaggaggac gcataatcgt ggaaaaagaa
    24901 acacaaaatg gaaaagctgc ggttttaggg ctgcagcatc tgctagcgat gtatgcagga
    24961 gcagtagcgg tgcctctttt gatcggtaca ggactaggct ttaatcaaga acagatgact
    25021 tatttgattt caattgatat ctttatgtgt ggattagcga cattattgca attgacagtt
    25081 aaccgatttt tcggaattgg cttgcctgtc gttttaggat gtgcgatcca agcagtagct
    25141 ccactgatct tgatcggaac caatgaagga gtaggagcta tctacggatc tattatcgct
    25201 tctgggatct ttgttgtgtt agtttctggt gtcttttcta aaattaaaaa actattccct
    25261 cctatagtaa caggaacggt tatcaccgtt attggtttga ctttgattcc tgtagcaatc
    25321 gagaaaatgg gtggaggtaa tgcaacagca gctgattttg gtgacaaaac aaatctgcta
    25381 cttgcatttg tgacgattct cctaattgta ggcgtgcaaa tgctggcaaa agggttcatt
    25441 cgttcaatcg cggtattgat tggtttagtc ggaggaagca tcttagctgc tttcatggga
    25501 atgattgatc tgagcgcgat tggagatgcg ccgttgttcc atgttccaca acccttttat
    25561 tttggtaaac caactttcga cgtatggtcg attttactaa tgatcctcat ttccatggtc
    25621 agcatggtag aatcaacagg tgtatatttt gcacttggtg acattactgg gaaaaatgtt
    25681 ggagaagaag aattgaaaaa gggatatcgt gcagaaggac ttgccgttat cttaggcggt
    25741 attttcaata cattccctta tactggcttt tctcaaaatg tcggattggt tcaactttcg
    25801 ggaatcaaaa caagaaaacc catctatttc tctgcattct tcttgattgt tttaggatta
    25861 ttccctaaaa tcggtgcgtt agcacaaatc atccctgagc cggtacttgg tggaggaatg
    25921 ttagtcatgt tcgggatggt ggcagtccaa ggaatccgta tgctgttgga agttgatttc
    25981 agcaatgata aaaatctatt gattgttgct gtttctgttg gatttgggct gggtttcaat
    26041 gttacgccga cattattcag tcaaatgccg caaacattgc aaatgttcac tggaaatggc
    26101 atcgtaatga gtagcattac ggctatcata ttgaatttga tctttaatgg attgaaaaaa
    26161 gatgaagaaa tattggaaga agccttcaag aagtaataga gcaaaagaaa ggttgtgaaa
    26221 tcagcgtttt gacctgattg ttagagaaac aaacggaaaa atagttcctc gtattttgcc
    26281 gtttgtttga gctaataccg agggtcagct gattgaacac cgttgaagga agaggtcgtg
    26341 agcctgccgt tcatctccga gtcacaagga acaatttcaa aaaaaagctt ctcatgtttg
    26401 ttgaatattg ttccttgtga ccgaggagtt ggcaggagaa caccgtttat ccataaaaag
    26461 gaatgtgacc taacttttgt cacattcctt ttttttatct ttaataaaca cgaacaataa
    26521 aatgtttttc tttgttaaca ttcgaaattt ctttgacatc aaaaaaagtg attgttaaaa
    26581 tatgaatgta gaaaaactgg gaggaaaaac aatgacagca aaaatctctg tgattatggg
    26641 gagtacttca gattgggaaa caatgaaaga agcatgtcaa atattggatg aattcggtgt
    26701 gtcttatgaa aaaaaggtcg tttctgctca tcgaacccca gatttgatgt ttgaatatgc
    26761 acaaaacgct cgaaaaaaag gaatcaaaat cattattgca ggagcagggg gagccgcgca
    26821 tctgccgggt atggtcgcat caaaaacaac tttgccggtt atcggtgtac cggtccaatc
    26881 acgaacatta aatggtttgg attcgcttct ttcgattgtc caaatgcctg gaggagtacc
    26941 tgtagctact acagcaatcg gaaaagcggg agcaattaat gctggactac ttgcgataca
    27001 gatgctttcc atgtatgatt tagaattgga ggctaaattg gctgaaagac gttcaatgtt
    27061 ggctaaaact gttatagaaa gtagtgatca acttggttaa acctttgttg cctggttcaa
    27121 cgatcgggat cgtcggtggc ggtcaattag gtcgtatgat ggcgattagt gcaaaagaaa
    27181 tgggctttaa agtaggtgtg ctggatcctg tgagcgattg tccagccgca caagttgcag
    27241 attggcacat tgaaagtgtc tatgatgaca cctttgcgct gaaagagctt gccagaagaa
    27301 cagatgtcat tacctatgaa ttcgaaaacg tcagtgtaga ggcgttaaat gcgattttac
    27361 ccatgtcatt tattcctcaa gggacagact tgcttgcgat tacgcaagac cgcctgttag
    27421 aaaaatcttt tttggaaacg aataacatcg tgattgctcc ttatgcaacg atcgtcagtc
    27481 cgacggatat ccaagatgcg attgacggga tcggctatcc ttgtgttttg aaaaccactc
    27541 gaggcggcta tgatggcaag gggcagtatg ttttgaaaag tcgggcggat ctagctcctg
    27601 ccatggacct tttaagagaa ggaacctgtg ttttagaagc atggatcccg tttgaaaaag
    27661 agatttcgat catggtggca ggaaatggtc aaggagattt cacgactttt ccggtcgtgg
    27721 aaaacatcca ccacaacaat attcttcatg aaacgattgc tccagccgcg attgatcagg
    27781 atgtgatcga ggaggctgag cgtattgccc gtgtgattgc agaagcagtg agcctttcag
    27841 gtgttttagg ggtagaaatg tttttaacaa aaacaggcgg gctatatgtg aatgaattag
    27901 ctcctcgtcc tcacaattct ggacattatt ctattgaagc ttgttctatg agtcagttcg
    27961 atgcccatat tcgaggtatt tgtggttggc cattaggaga aaaagtacgt ttgataagca
    28021 atgcagtaat ggtcaatgtt ttgggagaac aactgctgga aagctatcgc ttgattgaga
    28081 ataagccaga ctggcaattc catttctatg gaaaaaaaca agcaaaaaaa ggtcgcaaga
    28141 tgggacatat cactatcttg acagaagaca tccagcaaac gctggaagaa atcaaacaaa
    28201 cgaatatttg ggattagagg agaaaaaaca tgttagaacg ttatacacgc cctgaaatgg
    28261 ggaatatctg gacggaagag aacaaatacc gtgcgtggct cgaagtcgag attttagcag
    28321 atgaagcttg ggcagaactt ggtgaaatcc cgcaagaaga tgtgaaaaaa attcgtgagc
    28381 atgcatcatt tgatatcgat cggatcttgg aaatcgaaaa attaacacgc catgatgtcg
    28441 ttgcgtttac acgagcggtt tctgaaacat tgggagaaga aagaaaatgg gtccattatg
    28501 gtctaacaag tacggatgtc gtagatactg cttatggcta tctcatcaag caagcaaatg
    28561 atattttacg ggaagacttg aaacgtttta cggaaatcat tggcgaaaaa gcaaaagaac
    28621 acaaatatac agtgatgatg ggtcggacac acggtgtcca tgctgaacca actacttttg
    28681 gattgaaact tgccacatgg tattcagaaa tgaaacggaa catcgaacga tttgaacatg
    28741 cggcaaaagg agtagaagca ggaaaaatct caggagcagt gggaacgttc gcaaatatcc
    28801 cgccatttat tgaagagtat gtatgtaaac aattggggat ccgtccacaa gaaatctcta
    28861 ctcaagttct ccctcgggat ctacatgctg aatatttctc agcgatggcg cttattgcta
    28921 caagtattga acgttttgca acagagatac gcggattgca aaaatccgaa acacgtgaag
    28981 tagaagaatt ttttgcgaaa ggtcaaaaag gttcttctgc tatgccgcac aaaaggaatc
    29041 cgatcggttc agaaaatatg gctggtctag ccagagtggt gcgcggacac atggtcactg
    29101 cctatgaaaa tgtcacatta tggcatgaaa gagatatttc tcattcttca gcagaacgaa
    29161 tcatcttgcc tgataccacg attttattga attacatgtt aaatcgtttt ggcaatatcg
    29221 ttaaaaatct aacggtcttt cctgaaaaca tgaagcggaa tatgtctgca acatttggtt
    29281 tgatttatag ccagcgcgtt atgctgaaat tgatcgataa gagaatgaca agagaagaag
    29341 cttatgatct tgttcagcca aaaactgcgt acgcttggga caaccaagtg cagttccgcc
    29401 cgctgttaga agaagatcca accatcacat cggtattatc taaagaagaa atagacgatg
    29461 cctttgatta tcatcatcat ttgaaaaacg ttgacgtgat attcaaacga gtaggtttgg
    29521 aataaagaag agtgagttgc aaaattcaat taaaatagaa tagcaaaaat aaccaaaaaa
    29581 gaagcagatc cgttagcggt tctgcttctt ttagtttatt atattttctt atcaataata
    29641 ggaacctgat tttaaaagcg gctacctctt taccgtgcct ctttacatac aaaaaataga
    29701 ggaattaagc gtaaatggct tggctattat aactaaaatg ctggttatgg agatgttgca
    29761 gcaagttttc gagaaaagcg tattccatct cttgtccatt gaataagatc tggatacgat
    29821 aatgattttt gaaacgcttc tgttcatgaa tctgactgat tgaaagttcg cctttgtgtt
    29881 ctgtctgata aagaaaagtc cttttacggc attcagcaca gcgcttggtt gctcggcgga
    29941 tttttcggaa tgtataaaaa ctagtatctt tattgcataa ataaacgtct ttgatcgaca
    30001 gcaaatcatt atatagacag gaacgttctt cagctgttaa ttctgataaa aaaagctgac
    30061 cttgttttat tgcatcttcc atcggcaagt gcctcctcga acccattatc caaattttta
    30121 gttaattcta atataccatc attaagtata aatgtaaacg cttgttgatg gtataagatt
    30181 ttcgtttctg ataaaacacg aacattaaaa gaatctaatg ccttaaatgt acatattttt
    30241 gttgatttat aaaaagatga ttgctaaaat ttaaagtgaa aaaacgaaca aaaaacgatg
    30301 tatttgcttt taatgtaaat aaaaaggaga gacgtacatg gagaagaaag aacttttgta
    30361 tgaaggaaaa gccaaaaaaa tatatcttac ttctgatgag aacttgattt ggatagaata
    30421 tttagatcaa gcaactgcgt tgaatggcgc gaggaaagac cagataagtg gaaaaggaga
    30481 attgaataat caaatcacaa gtgcaatttt ccgttatctg actcaaagag gaataaaaaa
    30541 tcattttatt gaacaattgt ctaaaaccga acaattagca aaaaaagtac aaattatccc
    30601 tctggaagtg gttatccgaa atattgcagc aggaagtttc tcaaaacgtc taggtgttcc
    30661 cgaaggtaaa gaattcatca aaccaatcat tgaattctac tataaggatg accagttgga
    30721 tgatccattt atcaatgaag agcatatcta tttcttacaa cttgcaaagc cggaagaaat
    30781 cagtgagctg aaagcccaag cgttggctat taatgaaatt ttgaccgaat tatttgctaa
    30841 ggtcggtttg gttttagtag atttcaagct agaatttggc cggtcgaatg gacaaatttt
    30901 gcttgcggat gaagtaacac cggatacttg ccgattatgg gatgaacgta cgaatgaaca
    30961 tatggacaaa gacgtttacc gcagagatct aggtgatttg atcccagtct atcaagaagt
    31021 atataaccgt ctatcggaac taactgaaga aaaggagcga gtatgatgta tttcgtaaaa
    31081 gtatatgtaa cctataaaga ttcagtgtta gatcctcaag gggaggcagt aaaaaaagca
    31141 gtccatcgta tgggatatga aacaatcgaa gatatccgaa taggaaaata ctttgagata
    31201 caacttgctg atgcagaaga accaatcgat acagtgattg aaacgatttg tgacaagctg
    31261 cttgcaaatg taaatatgga aacataccga tatgaaatca aaaaaatgga ggaagtataa
    31321 catgaaattt gcggtcatcg tttttccagg ttcaaattgt gacgcagata tgttatgggc
    31381 agttcgcgag atcatgggcg ctgatgccga atttgtacgg catgatgagt cctctttaga
    31441 aggatttgat ggggttttac tgccgggagg attctcctat ggtgactatt tgagatgcgg
    31501 tgcgattgct cggttttcta caatcatgga agaagtgatt cgttttgctg aagaagggaa
    31561 accagtattc ggtacatgca atggattcca gatattgaca gaagcaggac ttttgccagg
    31621 tgtactgaga cgaaatgagt ctttgcattt tatttgcaaa actgtaccat tgaaagtcaa
    31681 ccccaagacg gcctttactt cagagtatga agccgacgaa ataatctatc ttccagttgc
    31741 tcatggggaa ggaaattatt tctgtgacga agaaacactt caagaactaa aaaaaaataa
    31801 tcagattgcc tttacttata atgacaacat caacggcagc gtggaaaaca ttgcagggat
    31861 tacgaacaaa gcagggaatg tgttaggaat gatgcctcat ccagaacgtg cagtagaaga
    31921 cttgctagga tcagaagatg ggaaacggtt ctttgcttcc attttaaaaa acttcggaaa
    31981 ggtgaccgta tagatgaaaa cattgaaaga accgacagct gaagagatca agaaaaaaag
    32041 aatctatgcc gaatggggat tgactgatga agaatatcga atgatcgaag aagatatctt
    32101 aggaagaatg cctaattata cggaaactgg actgttttct gttatgtgga gcgaacattg
    32161 ttcctataaa aattctaaac cggttctacg caaatttcct actagtggac ctcatgtgtt
    32221 gcaaggccct ggagaaggcg caggcatcgt cgacatcggt gatggactag cagttgtctt
    32281 caaagcagaa agtcacaatc atccttcagc cgtggagcct tatgaaggag ctgcgacagg
    32341 agttggcgga atcatcagag atattttcag catgggggct cgtccaattg cgttgctaga
    32401 ttcattgagg ttcggcgaat tagataatcc aagaacgaaa tatttactag aagaagtagt
    32461 tgcaggtatc ggcggatacg gcaattgtat cggcataccg actgtaggcg gcgaaattgc
    32521 atttgatcct tgttatgaag gaaacccatt agtcaatgca atgtgcgtag gtttgattga
    32581 acacaaacat atccagaaag ggcaagccgc tggcgtcggt aattcgatca tgtatgtagg
    32641 tgcaaaaaca ggtcgcgacg gtatccacgg agcaactttt gcctcagaag aatttaatca
    32701 agaagaagaa cagcaacgtt ctgctgtaca agtaggcgat ccttttatgg aaaagctgct
    32761 gcttgaagcg tgtttggaat taatcttgca tcattcggat tctctaatag gtatacagga
    32821 tatgggagca gcaggacttg tttcatctag tgcggaaatg gcttcaaaag ctggctcagg
    32881 acttatattg acattagatg aagtcccaca aagagaaact gggatgacac cttatgaaat
    32941 gatgttatcg gaatcacaag aacggatgtt gatttgtgtt aaatcaggag aggaagaaaa
    33001 aatccaagaa ctatttcaga agtatgatct agatgcagtc actatcggta aagtaacaga
    33061 cgacgggcaa tatcggctat atcatcaagg agaagaagta gcaaatctgc cagtcgatgc
    33121 attagctgaa gatgcaccag tttatcataa agaaatgaaa gaaccagctc gaatcgtaga
    33181 atttcagcag ttagctcctt atcagccagt tatcgaagaa cctggacaag tattgcttga
    33241 tctgctgcag caaccgacga ttgcttcaaa acgttcaatc tacgaaactt atgattcaca
    33301 agtacaaacc aatacagttg tccgtccagg aagcgatgct gctgtgatga gggttagagg
    33361 gacgaataaa gcgttagcta tgaccacaga ctgcaacgcg cgctatctgt atttggatcc
    33421 aaaaatcgga ggacaaatag cagtggcaga agctgctaga aatattattg ctagcggtgg
    33481 taagcccttg gcgatcaccg actgcctgaa ctatggttct cctgataaac cagaagtttt
    33541 ttgggaatta tcgacttcag ctgacggaat tgctgctgcg tgtgaaacgt taggaactcc
    33601 tgttatttca ggaaatgtct ctttatataa tgaaacggat ggtcaagcaa tctatccaac
    33661 accaatgatt ggtatggtcg gattgattga ggatcataaa catatcacta ctcaggaatt
    33721 caaaaaatca ggggatctaa tctatatatt aggtaagacg tttgcagatt ttgatggcag
    33781 tgaattacaa aagatgcagc ttggaagaat cgaaggtgtg atccgaaact ttgatctatc
    33841 cattgaaaag agaaaccaag agttagtatt gacagccatc caaaacggat tgattgaaag
    33901 tgctcatgac tgttcagaag gtggcttggc aattgcactg gcagaatcag ctttcaaaca
    33961 tcagctaggg atatctgtac agtttgaatt gtcctctgct caattatttg cagaaactca
    34021 atcaagattt gtgttgacag tcgcaccgga aaataagaca cgattcgaag aaatgatggg
    34081 agatgctgct gttttagcag gtaaggtgac ggatgaagcg ataatcgaaa tttcagcaac
    34141 tgacggtcag atcaaaatag aaactgcagt agcaagaaag tgctgggagg atgcaatcgt
    34201 atgtcttatg aagtgaagag tttaaatgaa gaatgcggga tcttcggtgt ttggggtcat
    34261 ccagacgccg ctagtgtggc atacttcggg ctccatagtc ttcagcatcg aggacaagaa
    34321 ggtgcaggta tcgtgtccaa tgatcgagga aagcttaagg ggcatcgaga tttggggctg
    34381 ctttctgagg tattcaaaga tcaaagaaaa ttgcagcagt taacaggaga agctgcaatc
    34441 ggacatgtac gttatgcaac agcaggcaat ggaagtgtgg acaatattca gccttttcta
    34501 ttcaaatttc atgatcagtc gatcggctta gcgcataatg gtaacttgat caatgctcgt
    34561 tcccttagaa aagagttaga ggaaaatggg gcgatcttcc attctaactc cgatacggag
    34621 atattgatgc atttgatccg acgaagtgaa gaaacagatt ttttaaataa attaaaaagt
    34681 gctttgaatg aagtcaaagg tggctttgcc tatttattaa tgacagaaac ggcaatgatt
    34741 gccgctttgg acccaaatgg ttttcgtcca ttagcaatcg gacaaatgaa aaacggagca
    34801 tacgtgattg cctcggaaac ttgtgcatta gaagttattg gggcacgttt tataagagat
    34861 gtccagcctg gtgagatagt gatcatcaat gacgaaggaa tccagattga ttgctttacg
    34921 aaggacacgc agctttctat ttgttcgatg gaatatatct attttgccag accagattca
    34981 aacatcgcag ggatcaatgt gcatactgca cggaaaaata tgggacggaa tttagcgaaa
    35041 gaatcgccag taaaagcaga tatggtcgtt ggcgtaccta attcttcttt gtcagccgca
    35101 agcggttatg cggaagctag tggaatccct tatgaaatcg gattagtaaa aaatcaatac
    35161 attgcccgaa catttatcca gccaacgcct gagctaagag agcaaggtgt tcgaatgaaa
    35221 ttatctgctg tacgaggagt agtggaaggt aaaaaggtga ttatggtcga tgattcaatt
    35281 gttcggggta cgacaagcag acggatcgtc catcttttga aagaagcagg ggcaaaagaa
    35341 gtccatgtga ggattgcttc tcctcctttg aaatatccat gtttttacgg gattgatatt
    35401 caaacgcgta aagaactcat tgcggcaaat cacacgattg atgaaatcaa agaatgtatc
    35461 ggtgcagatt ctttaggttt tttaagtgaa gagggtctga tcgaatcgat cggtctggaa
    35521 aaagatgctc cgtattcagg attgtgtatg gcttatttca acggagatta tccgacgccg
    35581 ttatatgact atgaagaaaa atatcaggaa tcactaaaag aaaaagtatc gttcttttaa
    35641 aagcagacca agaagggagt atatgaattc aatggcaaat gcatacgcaa aagctggcgt
    35701 agatgtcgaa gctggatatg aagtagtaga acggatcaag aagcatgtca aaaaaacgga
    35761 acgtttaggt atgatgggcg ctataggagg attcggcggt tgttttgatt tatcggtctt
    35821 tcaattaaaa gagccagtcc ttgtctcggg gaccgatggc gtggggacga aattagcagt
    35881 ggcaatcgaa gcagacaaac acgatacaat cgggatcgac tgcgtagcga tgtgtgtcaa
    35941 tgatatctta gcacaaggcg cagagccgtt atatttctta gactacttag caacggggaa
    36001 aaatgatccg ttacgtttgg aaaatgtagt aaaaggtgta gcagatggat gtgttcaagg
    36061 aaatatggcg ctgattggcg gagaaacagc tgaaatgcct ggtatgtact caggtaatga
    36121 ttatgatcta gccggatttg ctgtagggat agctgaaaaa tctcaattat tgacaggaga
    36181 aacgatcaac ccaggagatg tgttgcttgg aatagcatct agcgggattc attcaaatgg
    36241 gtactctctt gttcgcaaaa ttttctttga gcagcagcag ttttctttat catcaaaact
    36301 gccagaattg aaaaaaacac ttggcgaaga attgcttgag ccaacgaaaa tctatgtttc
    36361 ttccttgctt ccgctgatca aagaaaagaa aataaaagga gctgcacata tcactggtgg
    36421 agggtttgta gaaaatatcc cgcgaatgtt accagaatct atggctgcac aaatcaaact
    36481 tggctcatgg ccgattcttc caatattcgg ctgtttacaa aaatatggtg aaattcctga
    36541 gatggagatg tatgaaatct tcaatatggg catcggtatg gtcctggcag tcgaagaatc
    36601 gaaagtaaaa gaaatagtac acgaaattga gcaagctggc gaaaaagttt atgaaatcgg
    36661 gaaagtgatc gccaaagaaa aacatcgtgt ggtgtttata ggagaagaac gatgagaatc
    36721 gctgtttttg cttctggaaa cggaagcaac tttcaagcgc tagccgatta tctatcgaaa
    36781 aaaggattgg aatcttcgat tgactggttg ttttgtgatc agcctgaagc atatgttttg
    36841 aaacgtgcaa ctgcgttgag tgtaccggca gattgttttt cacctaaaga atttgattca
    36901 aaaaaagagt atgaagaagc aattttgcat aaattgaaag aaaaaaagat cgatttgatc
    36961 gtattagctg gatatatgcg aatcattgga ccggtattgc tgaaaaatta tgataaaaga
    37021 atcatcaata tccatccgtc tcttttacct gccttccctg gtttgcatgg catacgtgat
    37081 gcctttgaag ctggagtaaa agaaacgggt gtcacaattc attatatcga ccaaggtgta
    37141 gatactggac caatcatccg gcaggaaaaa gtgagaattg aacaggagga cacgttcgat
    37201 tctttagaag aaaaaatcca tagagtagag catcgaatct atccagaagt gattagtgaa
    37261 attattgaaa atggaggcta tctgaaatga caagagcatt gatcagtgta tcagataaaa
    37321 ctgggattgt agcattcgcc caaggtttga ttgaacaagg agtagaaatc atttcaacag
    37381 gaggaacaaa gcatgcgttg gataaagctg ggatcaaaac gctttcgatc gaagaagtga
    37441 cagggtttcc tgaaatgatg gatggccgtg tcaaaacact tcatcctaaa atccatggtg
    37501 gtcttttagg aagacgcgat ctccctagcc atatggaggc aatggaaacg gaaaatatcc
    37561 aaccaatcga ctttgtttgt gtcaatttat atcctttcaa agaaacgatt atgaaaccag
    37621 atgtcgaaat agcagaagct attgaaaaca ttgatatcgg tggtcctagt atgctccgta
    37681 gtgcagcaaa aaaccatgaa tttgtcacct ctgttgttga tccatctgac tatgaagaag
    37741 tactttcaga attacgtcag tatgggcata cttcactttc tttcagacaa aaactagcgg
    37801 caaaagtctt tcgtcatact gcggcatatg atgcactgat cgctcaatac ttaacggatt
    37861 gggtggaaga aaaagaaccg gaaaaattga cacttacgta tgaacgaaaa caaacgcttc
    37921 gttacggtga aaatagccat caagccgctg ccttttatca gtccgctctt ctggaaaaat
    37981 attcgatcgc agcagcaaaa caactccatg ggaaagaact ttcttataat aatatccgag
    38041 atgcagatgc tgcgctacgg atcatgaagg aatatgacga gccaacggta gtcgccttga
    38101 aacacatgaa tccttgtggt attgggacag catctacgat tttagaagcg tgggaagcag
    38161 cgtatgaagc agatcctgtt tcaatctttg gtgggatcat cgttttgaat cgagaagtag
    38221 atctgccaac agcagaacag atgcataagc tgtttctaga aatcatcatt gccccttctt
    38281 atacacaaga agctttggaa ttactgcaaa aaaagaaaaa catccgatta ctgacagtag
    38341 actttgcgca ggaagaaaat caaaatcgag aagaaacggt ctcagtctta ggtggacttc
    38401 ttgtacaaga tcaagatctg gcaatagaaa atgaagaaga gtggaaagtc gtgacaaaac
    38461 gtaagccgac tccagcagaa gcaaaagcat tagcgtttgc ttggagagct gtcaaacatg
    38521 tgaaatctaa tgcgatcgta ctggcaaacg aacgtcagac agtaggaatc ggagccgggc
    38581 agatgaatcg agtcggttca gtaaaaattg cgattgaaca agcgcaagag aaaatggaag
    38641 gtgcagtttt agctagcgat gcttattttc caatggatga ttcggttgaa tatgcagcca
    38701 aacatggtat aaaagcaatc attcagccag gaggaagcat caaagaccaa gattctattg
    38761 atatggcgaa taaatacgat ctagcaatgg tctttactga tgttcggcat tttagacatt
    38821 agagaggagt cggataaatg aacattttgg tgatcggtgc aggtggtcgt gaacatgcaa
    38881 taagtaaaaa acttttagcc agtccgaagg tggatacggt gtattgtgcg ccaggaaatc
    38941 cggggatgac aaaagatggt atcaattgtg tcgctatcag tgagcgagat cattcagcgt
    39001 taatccattt tgttaagaaa gaggctattg attggagtat cgttggtcct gaagttcctt
    39061 tgttaaatgg gatcgtcgat gattttatgg cggaaggatt gaaaatcttc ggtccgacaa
    39121 aagcagcagc tctgatcgaa ggttcgaaaa gttttgctaa acaattaatg gatacttatc
    39181 aaatcccgac agctaaatcc agaagttttg aatgttacga aaaagcagca gcgtatatca
    39241 aagaaaatgg tgcgccaatc gtagtgaaag cggacggctt agcagctggg aaaggtgtag
    39301 tcgtggctac cacagtgaag gaagcgctgg atgcggcaga acaaatgttg aaccagcatc
    39361 gatttgggga tagtagcaaa aaaatcgtcg tagaagagtt tttggcagga gaagaattct
    39421 cccttttggc gtttgtccgt aataccaagg tgtatccgat ggtcatttcg caagatcata
    39481 agcgggcatt tgataacgat aaagggccaa atacaggcgg aatgggtgct tattcaccag
    39541 taccgcaaat ttcaaaaaag atgattgaaa aagctgtgga agaagtttta aaaccagcgg
    39601 ctttgggaat gaaagaacta ggacgctctt tcacgggtgt tttatatgcg ggtttgattg
    39661 ctacgaagga aggaccaaaa gtgatcgaat tcaatgcgcg tttcggtgat cctgaaacgc
    39721 aagtcgttct ttctcggttg aagagtgact ttgcgcaagt aatcgatgat ttattagaga
    39781 atcgtacagt agagttaaag tggcagcaag aaggatacaa tgtaggcgtt gtggttgcag
    39841 ctgccggtta ccccgaagaa tatgagacag gaatggttct accagatttt ctggaagaag
    39901 agctttctgt ttactatgct ggagtttcct caaataacgg caaactagtt ggagcaggag
    39961 gacgtcttta tttagtagaa gcatacggtg agacgatcaa agaagcacag aaaaaaattt
    40021 acaccgcgtt aatggataaa acgacagatg gaacatttta tcgtacagat attggagaaa
    40081 aagctgccaa tagcgaactg atcgtgaagt aaatcagctg cttccattta taaaaaatac
    40141 aacaaacata atcggaagcg ccgattttag tgaagccttt tcataaagag tgtggtacac
    40201 ttttgttgtg tatataaata aggaggagtt cagatgaaaa aaattcaatt aggtacttct
    40261 gatcagaaag cagctgcagt gatcttaggc tgtatgcgta tcaacaatgc ggaagatcca
    40321 gtaaaagtga ttgagacagc ttatgaaaac ggcattgatt tttttgacca tgcagatatt
    40381 tatggaaacg gtgaatgtga agaaatcttt gcagatgctc tagcaaaaac atcaatcaaa
    40441 cgagaagatc tttttattca aacaaaatgt ggaatcgttc caggtgtgat gtttgatttt
    40501 tctaaaaaac atatcattga atctgtagaa aaaagtttga cccgtctgaa aatggattat
    40561 gtggatgctt tacttcttca tcgtccagat acattggtag aaccagagga agtagctgaa
    40621 gcgtttgatg aattggaacg gtcaggaaaa gttcgttatt ttggcgtcag caatcaaaaa
    40681 ccaatgcaaa tcgaattgct gaaaaaatat gttcgtcaac cattagtagc taatcagctg
    40741 caatttggct tgaaacatac tggaatgatc gatcaaggga ttcatgtcaa tatgacagat
    40801 gaagcaagta tcgatcatga cggtagtgta cttgattatt cccgattgca tgatatgacg
    40861 atccaagcat ggtcaccata ccagtatgga ttttttgaag gtgtatttat cgggaacgaa
    40921 aaattccctg aattaaacca aacattagaa gaactagcag ctaaatatca aacgacacca
    40981 actggcttgg cttctgcttg gattttacgc catccagcca atatgcaagt gatcgccggt
    41041 acgatgaacg tagggcgaat caaggaaatc gctcaagctt cagaaattaa tatgtctcgg
    41101 gaagattggt acgaattgta ccgtgctgct ggaaacattt taccttaaag attgtcataa
    41161 gcaggtcaaa agggctataa attaaaaaga cagaataact tgaaagctgt tttcagcttc
    41221 gagatattct gtcttttttt attgcaaatg gaaagagtat cattgtacgg atttcgttta
    41281 ttagttattt ttgtttttaa ggaaaagctg tgtccgatat tcttttggag aaatcccttg
    41341 ttttttctta aataaataac tgaaatagtt agggtcatta taaccaattt caaaagcaat
    41401 atctgaaata cgatagtctg attgctgcaa tatttttttt gctaattcga ttctttgttc
    41461 tgtcagataa tcgatgaatg tttggttaaa cgattgagaa aaaatcgtac tgaaatgaga
    41521 gggacttaat gcaacttgtt gagcgaccca agttaaggac atatctggat cggtaaaatt
    41581 ttctttgata aaatccaatg catggttcaa aattggctga tatttgttcc ttgaaggctg
    41641 tgagggcaga gcagttaaga aagaaatgaa catataaact gtcgaacggt aaagcgagtc
    41701 gtcggcgctg attgctaagc gttgactggt ggatgtgcaa tgaaccattt cttgcgggat
    41761 tttcttttct ttcaggcaga catgctggag tagcttagtc aagacaaata aacgatataa
    41821 tcgtgttcga gttggtgtgc cttgtggttt cgtcaagtgt tcgatgtact tagatacttc
    41881 gtttttcgat aatgaagaca aatcaagtga gaggtcaaag taaaagacag aatcaactgg
    41941 aagtttcgct tcttgaatca aatcctcata gctgataatt tgttctttaa gggaactggc
    42001 ggtttcaagt atcatctgcg tgatctcaaa agatgcaggt aattcgctga ttctttctgc
    42061 gacaggacca atggcgacag aaaaattatt tttttgtccc ttttctaatt catggaccaa
    42121 cgtttgggct acctgataac tggtctcgat cacattttct tcaagagaat caactattaa
    42181 aaatttgatg aatcgagagg aaacagcaga gaagatcact tgttgattct ccctaaataa
    42241 aaacttcaaa taatcactga gatgagcgta atcttcaaag tctgtactga cttggtttgc
    42301 tgctaataat acggtcattt ttttccctgc taaagagcga ttgaaagatt cagcaagttt
    42361 caatgtttca ctgatcgtaa gtgagccttt gaacaaaccg ttcaagaaat gatttttttt
    42421 caattcgaaa acaagatcag aagaagtgtg cgtttctttt tgctgcaaat ctaaagcagt
    42481 tactgctttt tctattgctt gtttcaattc gctactttta atcggtttaa gcagataatc
    42541 atctgcctgt acctggattg ctcctttcat ataatcgaaa tcgtcgaatc cactaataaa
    42601 tatgagacga gtccaaggaa gtagtttcct tgcttctttt gaaaaagtca acccgtccat
    42661 gaaaggcatt tggatatcag tcagaatgat gtcgggctgt aagtcgataa ttgaagacag
    42721 tgccatctca ccatctccag cttcgccgac ataagtgatt ggataataag aaccaaggac
    42781 agttatttgt tcccgcaagt tattgcgaat gaggtattcg tcttcgatga taaaaacttt
    42841 atacatgttt gtttcctcca attgttttgg gagatagagg gatcatcagt gtgacagttg
    42901 ttccttctcg gtatttgctg tcaatcgtga taggtttttg atcatttccg taataaagaa
    42961 ggagacgctt gtttacgttg taaagtccgt agccgatact gaaatctgaa tcgatccctt
    43021 tggctaactc tttacgtatt tctgccagtt tttctgcagg gatgccaatc ccgttgtcta
    43081 taactttgaa ttggatcatc tcatcaattt tgcatgtggt aatacgaata aatcctttgt
    43141 gacggacgta cttcgttcca tggtatacag cattttcaat caatggctgc aagatcattt
    43201 ttaaaataga aacaggaaaa agtgtttctg gtatatcgat cttatagtca agcatatggc
    43261 cgtatcttat ttttaagatg actagataat cattgatatg gctaatttct ttttcaagag
    43321 gaatccagtc ttgtcctttg cttaaagacg tacgaaaaaa gccggaaagt gcatgggtca
    43381 tagtcagagc ttcttcaaag cagtcttgtt cgatcaaaga aataatggca tccaaactgt
    43441 tataaataaa atggggagta atctgagctt gcaatacacg aacttcactt tgtgctaaat
    43501 ggtattgttt caaagcgttc tcccgtaaag actggtttag atcttccgcc attttattca
    43561 tgctagcggt aagtgtttgt aattccagtg tttccggcag ggttaaacga aagccaaggt
    43621 tccctgaaga aagttgttct gacatctcga tcagctgatt gatcggttct tggacctttc
    43681 tctctaaaaa gcgacgattc tttttcgcat agaaaaaaat ggtactaaga actccaagtt
    43741 ccactattgt taatagaatg agcgagcgga caagtgtcgt attttttttg cttgctaagt
    43801 cgatctccac acgaacaaaa tcttgtaaga tatctgacag cagttgagtg acagaatcta
    43861 cctgattgat gatctcttca ttggtatcca taaaatcttt tgccaagata ttattgatca
    43921 gctcgttttg ataatcttcc agtgtatcga tcgtacgtag cgatacatct aacgtactaa
    43981 tttctttaag tgtatttgta ttatttttga tctctcgaat atcattccta agttcttcta
    44041 ggatattttc ctcattgaac tcatctacgg ttacttggcc agaaatcaag tcccacatac
    44101 tttccaaaac tttttgatca accttcaaag caattgcatc tgctttttgg atatttgcga
    44161 tcgtctgttg ataaatcaaa agctgttgcg aatataacag tatgctcagt agcaaaggga
    44221 taacagcaaa tagaagcatg gctttgtttg cttgggcaaa aatctgtttt atgcttaaat
    44281 tttttgtcat gatacttctc cagtcaataa tttctggttg ggatgttagc tatattctgc
    44341 tgggaaaaga cagtctcgga aataaaaata tctttaggta atgtttttcc tgtttgaata
    44401 tttccaaaat aacgagtaac ggtattggct acataccagc cgacatcagg tttacactcg
    44461 actacacaat tgacgattcc tgagcgtagc ttctcgatca tatcttcttg tccatcaata
    44521 gttacaatga tcaaatcttc tccaggtttg attgatgttt cttttatcgc agctaaagca
    44581 ccgtgagtca tttcatcact atggctgtat aatacatcga tttcggataa atcatttgtt
    44641 tctaaatatc gtttcatctg gtcttttcct ttcatccgaa taaaatcacc gacaattcgg
    44701 tgaacaatag tcatcggagg tttatggtcg atggttccat ctttttttag ggttggttta
    44761 cgattgattg attccaaaaa tccttcggag cgtagcttgg tcggtgtgga gttctctgaa
    44821 ccagcaagtt ctaggattct gatttcctgt ttctttgaat ttgtgaagtg attgctgaca
    44881 aataaacccg cccgatttcc ttctgctttg aaactggggc caatgtgggt gacgaaaagc
    44941 tcgggatcat tcgtttgaat atgtctgtcg acaagtatga cagggatccc tgctcgcttt
    45001 gcttctttta atacagagtc ccacccggat tcttgcaaag gagtaaaaat gatcatatcc
    45061 actttatagg caatgaacgt ccgtatatct tggatttgcc gttcctgatt catgtagcca
    45121 tttcggtaga gaacttggta atcttctttt tcaagcgcag tgataattga ttcagtatgc
    45181 tttttccgcc agctactctc cgttcctgat tgcgaaaaac caacgactag tgggtcaggt
    45241 gcttcctttg tattaggtgt acaccccatc atttggtaag cgattacaac aagggctaaa
    45301 aaaaataaaa cacgtttcac tttaaatcac tccatctgga tttgttagta ctatcttatc
    45361 agataaaagg gaaaatcaaa gtcaaaagga atcaatcgaa aaaaatccaa gaaacttaaa
    45421 aaaatccaag acaaaaaaag tacacctaaa aaatttaaag taaatcccat aaaaaaatca
    45481 atgttaacgc tttctttatt agctatactc ggtgtatcaa ttgaaatggg ggataaaaaa
    45541 tgaaaaacaa atttagaaag attgttggga ctatcgctat tttgaccgca agcattctat
    45601 taagtgcgtg tggcaattca ggatctgcag atgatagtac ggggtatgta ggaatcgcta
    45661 tgccgaccaa atcagcagaa agatggatcg ctgatgggaa caacatggtc tcggaattag
    45721 aaaaactggg ttataaaaca gatcttcaat atggagaaga taaagtagaa aatcaagtag
    45781 cacaaataga aaatatgatt acaaaagggg tagatacact tgtgattgct tctatcgatg
    45841 gttcggcttt aactgatgtg ttagctaaag caaaagaagc agatatcaag gtgatcgcct
    45901 atgatcgttt actgatgaat tcagaaaatg tcgattatta cgcgactttt gataattttg
    45961 gagtaggtgt atcgcaagca gcttatattg aagagcactt aggattgaaa gaaggaaaag
    46021 gaccattcac gattgaatta tttggtggct cgcctgacga caacaacgca ctaatcaatt
    46081 acaacggagt gatgtctgtt ttacaaccat atatggacaa cggtcagttg gtcgtgccat
    46141 ctggacagac gagtttcagt caaatcgcta cgcttcgctg ggatggttct acggcgcaag
    46201 caaggatgga taatctgtta agcgcaaatt atactgacca aacattggat gctgttttgt
    46261 cgccatatga tccaataagt ttaggaatca tttcgtcatt aaaaggcgtg gggtatggga
    46321 gtgaaagtaa acctttacct gtgattactg gacaagatgc gacagttgct ggcgttaaat
    46381 cgatcattgc cggggaacaa acacaaacga tctttaaaga cacacgtatc ttagcaaaaa
    46441 atacgattga aatgatcaaa gcaatcagtg atggagaaga ggttccggtc aatgatactg
    46501 aaacttatga taatggggtg aaaactgtcc ctacgtattt agcaaataca gtatctgtcg
    46561 ataaagataa ttatcaagca gagctgatcg acaccgatta ttataaagaa tccgatctga
    46621 aaaattaaga ggaaccaaac aaggaactaa agagatctaa gtcagagaga ggataagaat
    46681 tatggcggat tgtattttaa aaatggcaga tatcaccaaa aaattttctg gaatccgagc
    46741 gttagattgc gtgaatctga tgattgaacg tggggaaatc catgcattgt gcggagaaaa
    46801 cggagcggga aaatcaacat tgatgaatgt cttgagcggc ttgtatccat atggctccta
    46861 tgacggggaa atcttttatg atggaaagct gtgtcaattt aaagatttga aagatagtga
    46921 agaaaaaggc atcgtcatca ttcatcaaga attagcacta agtccttatc tttcaataaa
    46981 agagaatatt tttctcggaa atgaacaagc agaaagaggc gtgattgatt gggaactgac
    47041 agaaaagaaa acatatgaac tgctgaataa agtcggtttg tctatcgacc cgaatcttct
    47101 agtatcccag attggcgtag ggcaacagca actagttgaa atagctaaag cattatcaaa
    47161 atccgtccgt ctgttgattt tggatgagcc taccgctgca ttgaatgaag aagaaagcgc
    47221 gaatttgctg agattgatcc gagagttgaa agagcaaggt gtaacctcca tcattatttc
    47281 acataagctg aatgaaatcg tggatatcgc agatcgaatc accattttac gggatggaca
    47341 gacgattgag acactagaaa atgaaatgat cagcgaagag catattattc gcggaatggt
    47401 gggcagagat ttagttgatc gttatcctga aagaaaaccg gatattggag aagtttattt
    47461 taaagtagaa gactggacgg tctatcaccc tcttgatcac gagcgaatca taaacgacca
    47521 catcaacttg catttgaaaa aaggagagat tgtaggaata gctggactga tgggagcggg
    47581 cagaactgaa ttcgctatga gtctatttgg acattcttat ggaagcaaga tatccggacg
    47641 tatattaaag gaaggggcag agatatcagt taagaccgtt ccttcagcca ttgcaaacgg
    47701 actcgcttat gtctcggagg accgaaaatc tttaggactg aatctgctga tggatattcg
    47761 ggaaaacgtg acgctgagca gtttggataa aataagtcaa aaaggagtat tagataaaga
    47821 aaaagaagta actgaggcag aaaatttccg gaaaaagatg cgtataaaaa caaactccat
    47881 ccatcaaatt gtcagtagtc ttagtggtgg gaatcaacaa aaagtcgttt tatccaagtg
    47941 gctgatgaca caacccgata ttcttttttt ggatgagcca acccgtggga tagatgttgg
    48001 ggcaaaatat gagatctaca cgattatcga agaaatggca gcaaatggca aagctgtctg
    48061 tcttatctct tctgaacttc ctgaaatatt agggatgtgt gatcgaatct atacgatgaa
    48121 cgaaggacgt attacaggag aagtctcgcg agaagatgca gatcaggaag tcttgatgaa
    48181 attaatgacg aaagaagagg tgggttaagt tggaacaggc aaaaaatctt acggataaaa
    48241 aagagaaaaa actaaatttg aaaagtagag cagctgatct ttttggtcgc tacagcatgg
    48301 tgatcatttt agcgggacta cttattgcgt ttcaattgat gacggatggt attttctggc
    48361 gtccattgaa tataactaac cttgttctgc aaaatagcca tatattagta ctagctgcag
    48421 ggatgttatt agttgtgctc ttaggtcatg tggatttgtc ggtagggtca gtgatggcgt
    48481 ttgttggtgc aattgcgggc atgatgatgg tcaatcgcca aatgaacccg tggatgacag
    48541 ttatcgcatg tcttgcagta ggcgggctga tcggcgcatg gcaaggtttt tgggtagctt
    48601 atgcagggat accggcgttt atcgtgactt tagcaggatt gctgatgttt cgtggactga
    48661 cacaagttgt tctaggaggc caatctctag caccttttcc agctgttttc caaaaaatgt
    48721 ctacgggtta tttaccagac ttaagcgaag gaagcagcct tcacttcttg acattgattt
    48781 taggaatgat catcacgatc gtgttagttg ttggtcaatg gcgaacaaga aatcgtcgga
    48841 aaaatcattt atttgaagtg gaatctccaa cagctttctt ggtaaaggcg gtatttacag
    48901 cagtcgttgt actaggaata acttatatct ttgcctctta tcaagggtat ccgattattt
    48961 tgatcattct tggtttgatc gttgcagcat atgggttttt gacaaataaa acagtagcag
    49021 gtcgacagat ttatgcgacg ggcggaaatc gaaaagcggc tgaactatca gggatcaaaa
    49081 caaagcgaat cacgttctgg gtattcgtca acatgggagt catggcagct ttagctggat
    49141 tagttttagc tgctcgattg aatgcggcaa cacctcaagc aggtacatcg atggaactgg
    49201 atgcaatggc ggcagtatat tttggtggtg cttcgacttc cggcggcatt ggaacaatca
    49261 tgggtgcgat tgtcggtggc ttggtcatgg gtgtattgaa caatggcatg tcgattttag
    49321 gcgtcggggt agactggcag caggcaatca aaggattgat cttgctttta gccgttgtgc
    49381 tagacttgta taataagaaa aaacgaacaa cgtaggagaa cgccggttat tcagaaaaaa
    49441 gactgtgaca agacatttgt cacagtcttt ttttcgctaa aagcgaacat tcattgtttc
    49501 gtttgtatag actaaaaata atatatgttt ttttaccatt cgtataaatt ctctttttgc
    49561 tcttgatttt tttgcttaat tgagttaaat tacatagggc gctaaaaaaa gccttgatta
    49621 aattaataat gttcgtgttt tgctggatgt gaacatcagg aggataatgt aatgaaagta
    49681 tttgattacg aagatattca attaattcct aataaatgta tcgtaaatag ccgttctgaa
    49741 tgtgatacaa cggtcacatt aggtaaacat acattcaaaa tgccagtagt gcctgccaac
    49801 atgcagacga ttattgatga aacaatcgca gaattcttag cggaaaatgg ttatttctat
    49861 atcatgcatc ggtttgatga agcagctcga attccgttta tcaaaaaaat gaaaaagcgt
    49921 ggattgatta cctcgatcag tgttggcgtc aagaaagagg aatattcctt tatagagaag
    49981 ttggcagaag aatcgctaaa tcctgattat atcactatcg acatcgcgca tggacatgct
    50041 aactcagtta ttgatatgat tcagcatatt aaaaaatatt tgcctgaaac ttttgtgatt
    50101 gccggtaatg ttggtacacc ggaagccgtc cgtgaattgg aaaatgcggg cgcagatgca
    50161 acaaaagtcg ggattggtcc aggaaaagta tgtattacaa aaatcaagac aggctttggg
    50221 actggaggct ggcaactggc agctcttaga tggtgtgcga aagcagctcg caagccgatc
    50281 atcgctgacg gtgggatcag aacacatggc gatattgcaa aatctgtccg ttttggtgcg
    50341 acaatggtca tgattggttc attgtttgcc ggtcacgagg aatctcctgg cgaaacaaaa
    50401 gtcgaaaatg gaatcgtgta taaagaatac tttggttctg cttcagaatt ccaaaaaggc
    50461 gaaaaacgaa atgttgaagg aaagaaaatc tggatccaac acaaaggatc tttgaaagat
    50521 acactagtgg aaatgcaaca agaccttcaa tcatctattt cttatgctgg aggaagagat
    50581 ctggaagcca ttcgaaaagt tgactatgtc atcgtgaaaa attcgatttt taatggagac
    50641 acaatctaaa aaataaataa aatattagga tgttgtgaaa aagttgtcct gcattaagta
    50701 ataagaacag ccaaacaaaa atagttcttt atatgttttg tttggctgga attattatcg
    50761 cagatacaag cttttgaaca tcattattca gaataaggga ctgtgataag atttttgtca
    50821 cagtccctta tgttttgcaa aaaaagtttt tcttttttct cgtaaattcg gtaaaatcaa
    50881 aagaaaaaat agacaataga aaagagaagc ttatgtggga aaaagtagag aaaaaacaag
    50941 gaccgattta tcgtcaaatt atggaacaga ttatgagaga aatcgaaaac ggaaggatca
    51001 atcctggaag tcaacttgaa tcagaacgaa aactagggca actttttggt gtgaatcgtt
    51061 ccaccgttgt ccatgcattg gaagagctta gggagcttgg ggtactaacg agcaaacgtg
    51121 gcagcggatg gtttgttaat cagactgaat gggggaaatt cgctgttcca agaatcgatt
    51181 ggcggcaaat gatctctcct cgttatgagc agacggactg gtatgagcaa aaaataagag
    51241 aagcaaagca gatccaaaaa acatcgtttc ttgatttata cgctagcgag atgccagatg
    51301 agcttttgcc gaattttgag tttccttctt attctcttga agaaatctta gcggaagaaa
    51361 aagaaatgga tcttttaggc tatactccgt tacgtaacaa aatcaaacgg tatttggaaa
    51421 gtaaatttga attggcattt tcccccaacc agcttcttgt gactggtggc ggtcagcaag
    51481 caatcttttt gattttacaa acgattcttt cagctggaga ggggatagct gtagagtcac
    51541 cttctttttt ttaccgatta cctcttttca aagcttcagg aacgcgttta tttgggatac
    51601 cgatggatga agaagggatc gacttagaaa aactgaaaga atcgatccat aaaaataaat
    51661 tgaaagcagt gcttatcaac ccgaattttc aaaaccctac aggaaaagtg atgagtcaaa
    51721 aacgacgaga aaagctagta gaattgtgtc gacagtatcg gcttccaatt attgaagacg
    51781 atgtatttac ggatctttca tttctaaacc aagaagaagt ccttcctata cgaacgattg
    51841 atccggataa tgtgttatac gtcggttcgt tatctagggt tttaggaaaa acaacgaaaa
    51901 tcggttgggt gataggacct gagactttta tctcgcaact agctcaagcg caagaaatga
    51961 tggagttttc gatgaatatc cttacacaaa tcacagtggc taatgtattt aatgaagcaa
    52021 ttgatttgaa aatgcaagat gtaagaaaaa agttgaaaga aaaaagccga ctgataagcg
    52081 cttggggaga ttcacaatcg tttttcaagc ttcattcaat tttaggtggt tactatgcct
    52141 ggattacttg ggatgggaaa aaactagacc ccgaactagc agaaaaagta gtagatatgg
    52201 gtcttggaat tgcaccaagt ctactttttg ggcaagatat aaatggaatc agaatcaatt
    52261 acagtaggct ggatgaaaac caaataccgt tgttttattc aaagatgaaa attctagaaa
    52321 agtggttaac agaataattt cacaaagtaa atagattaaa gaatataaca gcttggattt
    52381 aaatttcaag ctgtttcttt tttttcggaa aaagaatacg atataaagaa actaagaaaa
    52441 aaccattatt tgtacgtccg ttcacgatgt gtaaataaaa taaatgtttg caacaaaact
    52501 gtataacacc aacgttttta aatagaaaca gatggttgta agtttgatta gaaaatagaa
    52561 aaaatgcaga tgaaatataa aacgctttcc ttattgtgat tttattcact aatgctgtta
    52621 atatgcggat tggcataatt tcctttcatc gtgaaaattt gtgcttttag cttgtatttc
    52681 tcataaatcc atgataattt attaatgaag acggttaaat agtgatacag ttttattcac
    52741 tgtttcaatc gcagaatgaa gagattttct tatagatgag agaggaatgt gtgacaaatg
    52801 gcaaacaaaa aagcaccgat cgacttccaa gcactgctag atgaagtcaa tgcagatttc
    52861 ccagtatatc aagcacttga tcaagatgga aacgtagtta acaaagattt agtacctgat
    52921 ttatccgatg atgaactcgt tgaattaatg actcatatgg tatggtctcg tgtattagac
    52981 caacgttcaa cagcgctgaa ccgccaagga cgcctaggct tttttgcacc aactgctgga
    53041 caagaggcaa gtcagctggc tagtgcttac gcatttgata aagaagatgt tcttcttcca
    53101 ggttatcggg atgtacctca actagtaaaa catggtttac ctttatctca agctttttta
    53161 tggtctcgag gacatgctgc aggtaattct tatccggaag aattgaaagc tctaccacca
    53221 caaattatca tcggtgcaca atatgtacaa gcagccggtg ttgcattagg tttgaagaaa
    53281 cgaaacaaga aaaatgtcgt cttcacttat actggtgatg gcggttcatc acaaggtgat
    53341 ttttacgaag caatcaattt cgctggcgct taccatgcaa atgccgtatt ttatatccaa
    53401 aacaacgggt atgcgatctc tacacctcgt gaaaaacaaa ctgcagcaaa aacacttgca
    53461 caaaaagctg tcgcagctgg gattcctggt attcaagtcg atggaatgga tccgcttgca
    53521 gtatatactg tatctaaaat ggcacgggaa tgggcgatca gtggaaatgg accagtccta
    53581 atcgaaacac tgacttatcg ttatggacca catacactat ctggtgacga tccaacccgc
    53641 taccgtacaa aagacacaga tgacgattgg cagaaaaaag atccattgat ccgcttccgt
    53701 aaatatttga cggaaaaagg actttggtct gaagaaaaag aagaacaagt catcgaagca
    53761 actaaagaag aaatcaaagc agctattgct gaagccgaca aagtaccaaa acaaaaggtt
    53821 tcagatttct tgaaaaacat gttcgaagta tctccacaat caatcaaaga acaaattgca
    53881 atttatgaag cgaaggagtc gaaataatca tggcacaaaa aacaatgatc caagcaatca
    53941 cagatgcctt agcacttgaa ctagaaaatg acgagaatgt cgttgttttt ggtgaagatg
    54001 ttgggaaaaa cggaggagtt ttccgggcaa ctgaaggatt gcaggaaaag ttcggagaag
    54061 accgagtatt cgatactcct ttagctgaat ctggaatcgc aggattgagt ttcggtcttg
    54121 cgttagaagg atttcgtcca gttcctgaaa tccaattctt tggttttatt ctcgaagcaa
    54181 tggacgaagt agtagctcaa atggctcgta caagatatcg aatgagcggc actagaaatc
    54241 tacccatcac aattcgttcg ccatttggtg gcggtgttca tacaccagaa ttgcattcgg
    54301 ataatttaga aggtttgatc gctcagtctc ctggtattcg agtagtgatt ccttccaacc
    54361 cttatgatgc aaaaggacta ttgatttctt ctattagaag taacgatccg gttgttttcc
    54421 tagaacacat gaaactatat cgctcattcc gagaagaagt gccggatgaa gcttacgaag
    54481 ttcctttgga taaagcagca gttactcgtg agggaacaga tgtatctatt atcacatacg
    54541 gagcaatggt gcgtgaagca atcaaagcag cagacaatct tgcaaaagaa aatatatctg
    54601 ttgaaatcat tgatcttcgt acagttgcgc cattagatgt agaaacgatc attcaatccg
    54661 tggaaaaaac tggtcgcgta gttgttgtcc aagaagcaca acgacaagcg ggcgttgccg
    54721 cgcaagtagt ttctgagatc tcagaacgcg ctatcctttc attagaagcc ccaatcggac
    54781 gagtttctgc acctgataca gtcttcccat ttggacaagc agaaaatgtc tggttgccaa
    54841 atgcaaaaga tatcgaagac aaagtaaaag aaatcgcgga attttaagaa aagaagggac
    54901 gaaacaaagt catggcttat caatttaaat tgccggatat cggtgaagga atcgcagaag
    54961 gtgaaatcgt caaatggttc gtcaaaccag gagatacgat caatgaagat gatacattac
    55021 tagaagttca aaatgacaaa tcagtagaag aaatcccgtc acctgttaca ggaacggtta
    55081 aaaatgtgat tgttccagaa ggtaccgtag caaatgttgg ggatgtatta gtagaaatcg
    55141 atgcaccagg acacgaagac aatgaagggg acagtggtgt agccgcagaa tcccaaactc
    55201 cagctaaacc ggctgctgaa cccactgttg atacagaatc agctggatcg tcaagcgaag
    55261 gagtcttcca atttaagtta ccggatatcg gtgaaggaat cgcagaaggt gaaatcgtca
    55321 aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta gaagttcaaa
    55381 atgacaaatc agtagaagaa attccgtcac ctgtcacagg gacagttaaa aacgtgattg
    55441 ttccagaagg cactgtagca aatgttgggg atgtattagt agaaatcgat gctcctggac
    55501 acaatagtgc accgtcaact agtgcgccat cagctgaagc accaaaagaa aaagtggaaa
    55561 catcaggttc agcaagtgtc gttgaagctg ccgatccaaa taaacgtgta ttggctatgc
    55621 catctgttcg tcaatttgcc cgtgaaaaag atgtagatat ctcacaagta actgcaactg
    55681 gaaaaggtgg cagagtaaca aaagaggaca tcgaaaactt cttggcaggt ggtccaagca
    55741 gtgcaccagc gaaatcagaa gcgccagaag cggcagcacc gaaagaagca gctcctgcag
    55801 cagaaagcaa accagctgca ccagcaaaac cattcaagtc caacttagga gacttggaag
    55861 aacgtgtagc aatgacgcca acacgtaaag ctatcgctaa agcaatggtc aacagtaagc
    55921 atacagctcc acacgtgaca ttgcatgatg aagtagaagt gtctaaacta tgggataatc
    55981 ggaaacgatt taaagaagtt gctgctgcaa atggtacgaa acttactttc ttgccatatg
    56041 tcgtgaaagc tttaacagcg actgttaaga aatacccagt attgaatgca tctatcgacg
    56101 atgcaaacca agaaatcgtt tataaacatt actacaatat cggtattgca actgatacgg
    56161 atcacggact atatgtacca aatgtgaaag atgcagaccg caaaggaatg tttgctattg
    56221 cagacgaaat caatgagaaa gcaaaattag ctcatgacgg caaactatct gcagaagata
    56281 tgcgcaatgg aacaattacg atcagcaata tcggatctgt aggtggcggt tggtttacac
    56341 cagtcatcaa ctatccagaa gtagctattt taggtgtagg aacgattgca caacaaccaa
    56401 tcgtaaatgc tgaaggcgaa atcgttgtcg gtcgtgtgat gaaactgtca ttaagtttcg
    56461 atcaccgtat cgtagatgga gcaactgcgc aacaagcaat gaataatatc aaacgtcttt
    56521 tagctgatcc agagctatta atgatggaag gatgataaac aaatggtagt tggagatttt
    56581 gctgtagaat tagatacagt tgtaattggt gcgggacctg gtggctatgt agctgccatc
    56641 cgcgctgctg aaatgggaca aaaagtagca atcattgaaa gagagtatat tggcggtgtt
    56701 tgtttgaatg tcggctgtat tccttcaaaa gcactgatag ctgcaggaca ccattatcaa
    56761 gagtcactag attctgaaat gtttggagta actagtgaaa acgtcaaact agattttgca
    56821 aaaacacaag aatggaaaga aaacaaagtt gtccatacgt tgacttctgg tgttggtttc
    56881 ctattaaaaa aacataaggt tgaaacaatc gaaggagaag cgttcttcgt agatgatcac
    56941 acactacgcg tcattcatcc agattcagct caaacttatt cgttcaataa cgcaatcatc
    57001 gcaacaggtt cccgtccaat cgagattcca ggatttaaat tcggaggacg tgtgttagat
    57061 tctactggcg gattagcatt gaaagaagta cctaagaaat ttgtgatcat cggtggcggt
    57121 gtgattggtg ccgaattggg cggagcgtac gcaaacttag gagcagaagt aacgattctt
    57181 gaaggctcac cacaaatttt accaacttac gaaaaagatc tagtaaaatt agtagaagat
    57241 gatttcaaga aaaaaggcgt aacagtcgta acgaatgcaa tggcgaaaga agcagtcgat
    57301 aacggtgaca gcgtgacagt gaaatatgca gtggacggga aagaagaatc cgttactgct
    57361 gattatgtga tggtcactgt aggtcgtcgt ccgaatacag atgatatggg cttagaacaa
    57421 gcgggtgtcg aagtaggaga acgaggattg atcacggtgg ataaacaagg acgtacgaac
    57481 gtacctaaca tctatgccat cggtgatatc gttccagggg cggcattagc acacaaagcc
    57541 agttatgaag caaaaatcgc tgctgaagca atctctggca aaaaagtagc tgtagattat
    57601 aaagcaatgc cggcagtagc cttcactgat cctgaattgg cttctgtagg tatgacgatc
    57661 aaagaagcaa aagatgctgg tatcgaagca aaagcatata aattcccatt ttcagggaac
    57721 ggtcgggcat tatcgcttgg taaaacagaa ggattcatcc gtctagttac gacgatcgaa
    57781 gataacgtgc ttattggcgc gcaaatcggt ggagtcggcg caagtgatat ggtctctgaa
    57841 ttagctttag caatcgaatc aggaatgaat gctgaagata tcgccttgac gattcatcct
    57901 catccatctc ttggcgaaat cgtcatggat gcttcggaat tagcattagg tttaccaatc
    57961 catatttgat ttgaataata caggcgaaac gcaactgaaa aatcagttgc gttttgtttt
    58021 ttagaattat caataatatt attatgtaaa cttaaaaata tgacaacttc ttggtttatt
    58081 accacttcct atgctacact gaagaggaat atgaaatagg agagttgaag atgcaagaat
    58141 atcagtatcc acttgattta gattggacaa cagacgaaat ggtcattgta atgaagatgt
    58201 gggaagatct ggaacgtgcg aatgaaaaag ggataaacaa tgaagctttt ttgaagactt
    58261 atcagcagtt taaaactgtt gtcaaatcca ttggtgagga aaaacgattg ggacgggaat
    58321 ttgaaaaagc ttccggttat tctttatatc gtacagtgca gcaagcaaaa aaaaatccaa
    58381 acaaaacttt gagaatgaac gggtgagata aatggaacag atgattgatc atatcaagtc
    58441 ctggcttgaa gaagctggtg agaaaatcaa atcttctcaa caaacattaa caatctcgca
    58501 aaaatcaaat cgaacggatc tagtaacaaa tgtcgatcga aacatccaga attttctaat
    58561 cgaaaaaatc cattcctttg atccagaggc gaaaatattg gcagaagaag aagggtgtaa
    58621 tcaattatcg gatctcgatg gaagagtctt tatcatcgat cctattgatg gcaccttgaa
    58681 ttttgtgatt gaaggggaaa atttttgtat tatgctcgct gtttatgaat ccggcgttgg
    58741 aaagcttggt ttcatttatg acgtgatgag aaatgaactt ttttggggtg gaaaaggaat
    58801 aggcgtgtat aaaaatgatg agccattgcc tagaccagca aataaatcct tatcggaagg
    58861 cttacttggt gtgaatagtt atcttttcgg tcataataaa tatggaatcc gagaaattgc
    58921 ggaaagcagc atggggacac gtatgtacgg atgcgctggt cttgaactag tggcaatctt
    58981 gaaaggaaac cacattgctt atatttcaaa ccttagccct tgggattatg cagcgggaaa
    59041 tgtcttattg gaagagtttg gtatggtaac aagcggtctt tttggtactc ctttgacatt
    59101 tgaaaaaagg gaatactatt tagcagggac ttcttgtgca tatgcagaaa tcgcagacct
    59161 tttgaaaaaa gaaggctgaa aaaaaggtag aaatcattca caaaaatgat aaaaacgagc
    59221 aaaagattaa ttttctcgaa aaaatgaaaa cattttacta tatttcatga aaaaagtctg
    59281 ctataattag cagtcgagta aaatttgccc tgtcataaag aaccaataaa aaaggagtta
    59341 gttacattga attatagaaa cgatatccgt aacgtcgcaa ttattgccca cgttgaccac
    59401 ggaaaaacaa cattagttga tgaactatta aaacaatcag atacattaga cgcacatacg
    59461 caattgcaag aacgtgcgat ggactcaaat gcgctagaaa aagaacgtgg tatcacgatt
    59521 ttagccaaaa acacagctgt agactataaa ggtattcgcg taaacatcat ggatactcca
    59581 ggacacgcgg acttcggtgg cgaagtagaa cggatcatga aaatggttga cggcgttgtg
    59641 ttggtcgtag atgcgtatga aggaacaatg cctcaaacac gttttgtatt gaaaaaagca
    59701 ctggaacaac atatcacacc aatcgttgtc gtaaacaaga ttgacaaacc ttctgctcgt
    59761 cctgagcatg tcgtagatga agttcttgaa ctattcatcg aattaggagc agatgatgat
    59821 cagttagact ttcctgtgat ttatgcatct gcactaaatg gtacgtcaag cttgtcagat
    59881 gatccagcag atcaagaacc aaccatggca cctatttttg atacaattat tgaaaaaatc
    59941 cctgctcctg tcgataacag cgacgaacca ttacaattcc aagtttcatt acttgactac
    60001 aacgattatg taggtcgtat cggaatcgga cgtgtattta gaggaacaat caaagtagga
    60061 gaccaagtag cattaattaa attagacgga acagttaaga aattccgtgt aacgaaatta
    60121 tttggtttct ttggactaaa acgtctagag attcaagaag caaaagctgg agacttgatt
    60181 gctgtctcag gtatggaaga tatctttgtc ggtgaaacag ttactcctgt ggatcatcaa
    60241 gatgcgttac ctatccttca cattgacgaa ccaacattgc aaatgacttt cttagttaat
    60301 aattcaccat ttgccggtcg agaaggtaaa ttcgtaaccg ctcgtaagat tgaagaacgt
    60361 ttgatggcag aacttcaaac agatgtatcc ttacgagttg aaccaacaaa ctctccagat
    60421 gcatggacag tttctggtcg tggagaattg catttgtcta tcttgattga aaacatgcgc
    60481 cgtgagggat acgaattgca agtatctcgt ccagaagtta ttgaaaaaga aatcgacggt
    60541 gtaaaatgcg aaccgtttga acgcgtgcaa atcgatacac cagaagaata tatgggtagt
    60601 gttatcgagt ccttgagctt acgtaaaggt gaaatgcaag atatggtcca tacaggaaac
    60661 ggacaaatcc gtttgacatt cttaacacct gcccgcggtt tgattggtta ttcaactgaa
    60721 ttcctttcaa tgacacgtgg ttacggaatc atgaaccata cttttgacca atatctgcca
    60781 atgcttcctg gtcaaattgg cggacgtcac caaggggcgc ttgtttcgat cgatacagga
    60841 aaagcaacga cttattctat catgagtatc gaagaacgcg gtacagtctt cgtagaacca
    60901 ggtacagaag tatatgaagg aatgattatc ggggaaaaca gccgtgataa tgatttgact
    60961 gtcaacatca cgaaagcaaa acaaatgaca aacgtacggt ctgctactaa agaccaaaca
    61021 tctgtcatca aaaaaccaaa acaattgacg ttggaagaat ctttggaatt cttgaatgat
    61081 gatgaatatt gcgaagtaac accagaaagc attcgcttga gaaaacaaat tttagagaaa
    61141 aatgctcgtg aaaaagcatc taaaaagaaa aaataatctg taaaaggatg aagagagaaa
    61201 ccagcttgtt ataaaaaata gctggtttct ttttttgtcc aactcttttc tgtggagaag
    61261 tcatctttgt caatggacat aaattcagaa aatacgccga aagacgttta aaagactttt
    61321 aaaaaactta tttctagaga gtttttgttt cataataaga taatgtttca cgaaaggaga
    61381 tcaacttgtc cttcgaagaa aatcgaagta aaatggcaag agaaaggagc gggaagatga
    61441 acgacttatt aaaacaatac tttggctatg atgagtttag acctggtcaa aaagaaatta
    61501 tccagaaagt cattgatcag gaaaatgtat taggaatcat gcctaccgga agtgggaaat
    61561 caatctgtta ccagcttcca gctttactat tagatgggct tactgtggtt gtgtcccctt
    61621 taatctcttt gatgaaggat caggtggacg cggcgaatca attaggtata cccgccactt
    61681 ttatcaatag ctcgttagat ggttacgaaa cagctagacg cttccaagaa atcgatagac
    61741 agcagtaccg tttactttat atcgctcctg aacgttttat catgccggat tttatccaag
    61801 caatgaagcg atggaacgtc cgtatgatcg ctattgacga ggcacattgt atctctcagt
    61861 gggggcatga tttccgccca agttatttac agatggcgaa ccagctagat caactgccaa
    61921 atcgtcctgt aattgttgct ttgacagcta cagcgactgt gcaagtagct gctgacataa
    61981 aaagactttt aaaaattcca gaaaacaacc atattcagac tggttttgaa cgagaaaatc
    62041 tacgatttca agtaattaaa gatcaaaaaa aagaacaata tctaatcgaa tatttaaaga
    62101 tcaacaaaaa tcaatctggt atcatttatg cagcaacgag aaaagaagta gaccgtctct
    62161 atcatttgct taaaaaattc gatttttccg tgggtagata tcatggtggt ctaaatgaga
    62221 atgagcgaac agaaatgcaa gaagcctttt tatacgatcg cttgcagctg attgtagcga
    62281 caaatgcatt tggtatgggt ataaataaaa gcaatgtccg ttttgttatc cattatcaaa
    62341 ttcctggctc tctagaagca tactatcagg aagctggtcg ggcgggaaga gatggtcttt
    62401 ccagtgaagc catcctgctt ttctctcctc aagatatcca agtccaaaag ttttttatcc
    62461 agcagtccca aagagaagaa gggcaaaagc aaaaagaata tgaaaaatta aaagcgatga
    62521 cagaatacgt gtatattgag tcctgtcttc agcaatacat cctaaactat tttggcgaga
    62581 caagcagtcc gtgcaaccgt tgtggtaact gtttagatga cagagaaata gtagaagtaa
    62641 cgacagaagc acagatggtt ctttcttgct taaaacgtat gggtgagaac tatggtaaac
    62701 aaatgctgat gaaagtctta gcaggatcga aagaacaaaa gctgcaagct ttaggttttg
    62761 gacatttatc tacctatgga ctgatgaaaa accaatcgca aaaagaaacg atgcagttaa
    62821 ttgaatattt gatatcgaat ggctatcttc tgaccatcaa tggtgagtat cctgttttga
    62881 aagtaacaga aagagggata caagtattga aaggacaaga atctgtttat cgaaaggaac
    62941 ccaagaaagt ccagcagcta tcggatgaag aaaccgatac actatttgaa gtgctgcggg
    63001 aactgcgaac ggatctagca tcagaagcag gcgttccccc gtatgtcgta ttttcagatt
    63061 ccacattgaa agaaatgagc cgaatacgtc catcaagcag attggagatg cttcagataa
    63121 aaggagttgg ccaaagcaag cttgataaat atggcgaagc ctttttatct cggataaaaa
    63181 atgcggactc taacgttctg gataagtaga aagaacgaat acgtaaaaat gaataaaaac
    63241 aactggttaa atctgttttt tttgctcctt atgaaaatca aatatgttat aattaaggaa
    63301 ttagaatggg aggtaagcac agatggattc tttgtcgaaa aaacttgcga tccaagtatt
    63361 aaatgatgaa gcagaacgga tcaaacgatt aatccgaaat caaaacaaca gtctctgtat
    63421 ctcacaatgc aaagccttcg aagaagtggt agatacacag atgtacggct tttcccggca
    63481 agtcggtttt gctgtccgta taggagtaat cggaaagaac gagggccagc tgatgttaag
    63541 tgagctagaa cgagaattga atcagttata tagtgaggtt taccaagaaa tttatgataa
    63601 aaaagaagtt ggcaaggagg aatagacttg cctaagaaag tgaaaaaaag gcatctatta
    63661 gactatagca tcttgattcc ctatttaatt ttatgtgtat tgggattgat catggtatat
    63721 agttctacgt cgtatctatt attagaaaac ggacaaaatc cgtccgcatc agtcattaac
    63781 cagagtattt tttgggtgct tagcttgatt gctatcgcac tactttataa aatgaaaaca
    63841 gatgttttga aaaaccagcg tttgatcatg gcagccatcg cagttttgac gattttgctg
    63901 ctgattgttg tgttttttgg taaggagatc aatggggcga aaggttggct gcaaattgca
    63961 ggattctcga tccaacctgc cgaataccta aaaatcattt ctatctggta cctgtctctg
    64021 actttatcta aaagacaaaa cagtgtacaa aaaaattttc ttgggactgt gaaacgtcca
    64081 cttgcaatgg ttatcggact tactgcatta gtcgctattc ttcccgattt tggtaatgcg
    64141 gcagttatct ttttgattat tttggttctg cttttagcca gcggagtcaa ttatgtgtat
    64201 actttgattg taggagtagg aggcttttgt ctaagtactt ttacgatctg gctgatcaat
    64261 atcacaaacg gaaagatctt acccggacgt ttacagtata tctataatcg atttgctatt
    64321 taccaaaatc ctttctcaga cgaattaaat aaagggcatc aactagtcaa cggctactat
    64381 gccatgttca acggaggact atttggcagg ggattaggta acagtatcca gaaaaaagga
    64441 tttttacaag aagcacaaac cgattttatt tatgcaatcg tagtggaaga actgggagtg
    64501 attatgggga ttttgatatt agcgttgcta ttctttatga ttgtgcgcat tgtccttgta
    64561 ggtatccgtt caaaagatcc gttcaattcg cttttgtgca ttgggatcgg cgcaatgttt
    64621 ttgatccaag tatttgtcaa tcttggagga attactggcg ttattccttt gacagggatc
    64681 acgttcccat ttttaagtca aggaggctcc agtttgctga tgctttcgat ttgtgtcggc
    64741 tttgtcctca acatcagtgc ggatgaaaaa cgcaagagct taggtttata ataaaaaaag
    64801 atgtaggagt ggttcgatga aaaaagtttt agttgctaac aggggtgaaa tcgctgtacg
    64861 tgtatttcgt gcttgtacag aattaggaat taaaactgtt ggaatctatg cagaagaaga
    64921 tgaatattcc gtacaccgtt tcaaagcgga tgaagcatat ttagtaggac aaggaaaaaa
    64981 accgattgat gcgtatctag atattgaagg gatcatttct atcgcgaaag aatgcggagc
    65041 tgacgctatt catccgggtt acggtctttt gtcggaaaac ttgaattttg cgcaacggtg
    65101 cgaagaagaa ggcatcattt ttgttggacc caaactgcat catttagata tttttggaga
    65161 taaaatcaaa gcaaaagctg cagctatcga agcggggatt gcttcgattc caggcacaga
    65221 tggaccaatc gcttctatag acgatgcctt ggagtttgcg aaacaatacg gttatccgat
    65281 tatgatcaag gcagctctag gcggcggcgg acgcggcatg cgtgtagctc acgatgaaaa
    65341 gagtgcaaga gagggctacg aacgtgcgaa aagcgaagca aaagcagcct ttggtagtga
    65401 tgaagtgtat gttgaaaaat acatcgctaa tcctaagcat atcgaagtac agattctcgg
    65461 ggatacgcat ggaaacgtca tccatctttt tgaaagagat tgttctgttc agcgccgtca
    65521 ccaaaaagta gtagaagtag cgccttgtgt ctctatgaat gaacagcaac gtcaaaaaat
    65581 ctgccaggca gctgtccaat tgatgaaata tgtcgggtat gtcaacgcag gtacagtaga
    65641 atttcttgtt gaaggagatg atttttactt tatcgaagtc aaccctcgcg tccaagtgga
    65701 acatacgatc acagaaatga ttacagatat tgatatcgta acaacgcaac tgttgattgc
    65761 tcaaggtttg gatctgcata aagaaatcgg attgcctcag caagaaggaa ttaaattaaa
    65821 tggttcagcc attcaatgcc gaatcactac agaagacccg ttgaataact ttttaccaga
    65881 cacagggaaa atcgatacgt atcgttcacc tggtggtttt ggcgtacgtc tggatgtcgg
    65941 aaatgcttac gcgggctatg tagtgacacc gtattttgat tcattgctag taaaagtatg
    66001 tacgcatggt gctacctttg aaacagccat tcagaaaatg gaacgttgct tgaaagaatt
    66061 tagaatccgt ggagtgaaaa caaacattcc atttatgctc aatgtcatca cacatcctga
    66121 attccaatca ggaaatgcaa aaacaacctt cattgatagt acagcaacat tatttgaatt
    66181 tcctcgacta cgagaccgcg gaaacaaaac gatgaaatat atcggtgaaa ttactgtgaa
    66241 tggttttcca ggtatcgaaa gtggcgaaaa accattttat gaagaaccac gtatgcctaa
    66301 agatctaatc acaagaactg attacgtaac ggctaagaat gtattagatg cgaagggtgc
    66361 cgatgctttg gtcgaatgga tcaaaggaca ggaaaatttg ttgttgacgg atacgacatt
    66421 tagagacgcc catcaaagtc tgctagcaac tcgtgttcgg acaaaggatt tcaagcagat
    66481 tgcacgtttg actggagaag gtcttcctga actcttttca agtgagatgt gggggggagc
    66541 aacatttgat gtggcttacc gctttttgaa tgaagatcct tggcaacggt tgagaaaaat
    66601 tcgttcttta atgcctaata cgttgctgca aatgcttttc agaggttcaa atgccgttgg
    66661 gtattctaat tatcctgaca atgtattggt ggaatttgtc aaagaagcag cagcgcaagg
    66721 aatcgatgta tttcgaatct ttgatagttt gaactggact ccacaaatgg aaaaaagtat
    66781 ccaagctgta cgggatactg gtaaaatcgc agaggcagct atttgctata ctggcgatat
    66841 caacgatcca agtcgggcaa aatacaatgt tcagtattat aaagacatgg caaaggaact
    66901 agaacaactg ggtgcgcata tcattgcaat caaagatatg gctgggctgc ttaaaccgca
    66961 ggcagcttat cgtttgatta gtgaattgaa agaaacgaca gatctgccaa tccatctgca
    67021 tactcatgat accagcggga atggaatcat cacttattct gctgcttcaa aagcaggagt
    67081 agacatcgtt gacgtggcaa tgagtgcaat gagtgggaat actagtcagc ctagcatgag
    67141 cagcttgtat tatgcactgg tcaatggtcc acggctgcca gaaatcacga ttgaaaatgc
    67201 acagaaatta aaccattatt gggaagatgt gcgcatgtat tacaaaccgt ttgaaaacgg
    67261 cttgaatgct cctgaaacag aagtatatat gcatgaaatg ccaggaggac agtattcgaa
    67321 tctacagcaa caggcaaaag ctgtcggatt aggtcatcgc tgggatgaaa tcaaacaaat
    67381 gtatcatact gtcaacttga tgtttggcga tatcgttaaa gtaactccat catctaaagt
    67441 agttggagat atggcactat ttatggtcca aaatgatctt acagaagaag atatttatga
    67501 aaaaggcgaa acactaagtt tccctgaatc tgttgtgact ttcttccaag gagaactagg
    67561 gcaacccgtt ggcggatttc ctaaaaaatt gcaaaagatt attcttaaag gcagacctgc
    67621 attgaatgaa cgtccaggtc ttttggctga atcagtcgac ttcaacgaag taaaaaaaga
    67681 attggcagaa aaaattggct atgaaccaaa acaagacgaa gtattaagct atttgatgta
    67741 tccgcaagtc tttttggact atcaaaaagc atataatcaa tttggcgatg ttacattact
    67801 ggacacacca acatttttcc aaggtatacg tttgggtgaa acaatcaatg tacaaatcga
    67861 acgcggaaaa acgcttatca ttcgtttaga tgaaatcgga gaacccgata tcgaagggaa
    67921 tcgcgtactg ttcttcaatt tgaatggaca aagacgtgaa atcactatca aagataattc
    67981 gatcatcagt acggtccaaa cccgattgaa agctgaaccg acaaaccgag aacaaattgg
    68041 agcaacgatg tctggttctg ttttggatgt attagtgaaa aaaggcgata acgttaaaaa
    68101 aggtgatacg ttgatgatta ctgaagcgat gaaaatggaa acggccatcg aagcacgttt
    68161 tgacggagaa gtcgcacatg tatatgtgtc ttcaggagac actatttcgt ctggtgacct
    68221 tttgattgaa gtgactgaga aataataagc gaaaggtggg gaaacatgaa aagactgggt
    68281 ttgttttggc tgattctgct attagttatt gtggcattct acatggaacc agtcttgttt
    68341 ccgccaaaac ttgaagtgaa ggaaaactct gatcaacaaa tatcaaacca aatgacaacg
    68401 tggaaatacc aggagcttaa agcaactggt ttttctactt atatcggaaa accgatcgat
    68461 cagctggaaa aggattttgg ccaagcctat gatcgattaa ctagcggatt tggttttgaa
    68521 acaagatatt atgaaaataa agctagtcat ctcacatttg aagcgaacat ccaagacagc
    68581 agagtcacaa ctgttaaagt actgcaaaca gggcctgctg atatcgcgcc gttttattta
    68641 gggatgacga tgcaagatct tacgaaaatc actactatct atactaattt cacttttgag
    68701 taccatgata cagaagttgg aatcgaacta atggaagagg atatgaatta tcgtccgcta
    68761 attgcttttg ataacgacac ttttgctatt ttattttttg atcaaacaac aaacggccta
    68821 ttttcagttg tgtatttaga taaagatagt cttttgaaac tattgccata tcaagtgttt
    68881 ggtgaaggcc ttccacatta tcaagcagat aaatcggctg attgggaatc aatcaatcgc
    68941 gttaaagaac gaaaaagtac gactttatta aatatgctta gaagagaaga cgaacttccc
    69001 atatacaatc aaacacttgc ctttcaaaac cacagtcagc tgctactaca tgattttttg
    69061 acaaggcctg aggaaatatt gtcagaggaa cgtatggctg attggcaaaa atcgctaggc
    69121 agtgctcaaa cgacagtgaa attctcactg acgaatgatg aattggagaa gttaatcagt
    69181 aaacaaaaat tagaaaatac tagtgggcta tttattcatc cggcgattga cgctactttt
    69241 tcgtttttat attggtacag cgatccttac aaccatgacc gtttcatgga cccgggaacg
    69301 gattctgtag gcattgcttt ttctaaagaa aatatgttag tcttattgca agaagaaaac
    69361 ggagaaagta gtgatagcag tgatcgttaa cgaagagctg tttcaactgg aggatcaatg
    69421 cctccaagtc gctgaaatga taaaaaagag taaaacgatg gcttcttatc ttgaacataa
    69481 acagtcaatg gaagaatctg caaaagtttg ccagttgaaa gaagcgttct tgtctaagaa
    69541 agaagcattt gaaaatgtag cggcatatgg tgagtatgca cctgattatc gtgaaaaaaa
    69601 acgagttgtt cgaaaagcaa aaagacagct tgatatggat gagcatgttg cagctttccg
    69661 atatagtgaa acacagctgc aaagtctgtt ggatcaaatt gtccaagtac ttgccgaaga
    69721 agtttctaat gaaatcaaag tagatgcagg tagcccgttt tttgaaacga aaaaacactt
    69781 tggatgcgga ggtaattgtc atgcaattag acaatagtga atttgaaata acaaaacgac
    69841 gcgggctgat cgtatgggtc tacagcttaa aacaattaaa gaatctgaaa aagttcggct
    69901 tgttgcatta tgtctcaaga agaatgaaat atgtcgtgct ttacttaaat gaagagacat
    69961 tggaagaaac agaagaacga atccgtaaat tacattttgt tcgaaacgta gaacgttctt
    70021 accgaccgga tatcgaaatg aattttgccg aaaaaatagg aaacaaaaca gtattaaaag
    70081 acgaaggttt cgaaattgaa gagctaaata cagaaatccg attagctgaa catctttaaa
    70141 aatctcttat gagcagtttt taaataaaaa ataacttgga taacgatcga tttttgatca
    70201 ttgtccaagt atttttttgg tatactagta ccagtaccat ttctaaggag tgagtagatg
    70261 cggataatat caggaaatta tggcgggcgc cgtttaaaaa gtttagcagg ggcgaacacc
    70321 agaccaacta cagataaagt aaaagaatcc atattcaata tgattggacc atattttgat
    70381 ggagagacag tattggatct gtttgcagga agcggtggtt tagctatcga agcagtatct
    70441 agaggctgca gtcatgcggt atgcgtagac aaaaattacc aagcgctaaa aatcatcaaa
    70501 gaaaacatcg aaattacgaa agaaccagag aaatttacca caataaaact tgatgcggac
    70561 aaagcaatcg aacggctagc agcggagaaa caacaattcg actacttgtt tcttgatccg
    70621 ccatatgcaa aacaaaaaat aatcgatcaa atccataaaa tggaagaact gggacttttt
    70681 tctaaaaccg cagttatcgt atgcgaaacg gataaaacag tcgaattgcc agaaactgtg
    70741 gctggattcc atcaaataag aaaacagatt tatggcataa cggccgtaac tatctataga
    70801 aaagagggaa atcaatgaaa cgtgcattat tcccaggaag ttttgatcct tttacaaaag
    70861 gtcacttaga tacggtggaa cgtgcggcta aattattcga tgaggtagta attggtgttt
    70921 ttatcaatac ttcaaagaaa agtttgtttc ccccagaaga aagaatgaca ttgatcacaa
    70981 aagctgtttc tcatcttcct aatgtaaaag tcatgcatca agaaaatcaa ttgacggtag
    71041 aaacagcaaa agagattggt gcagatgcgt tgatcagagg catacgaagt atcaaagact
    71101 ttgaatatga acgagagatt gctcagatga atcatcatct atatgatgaa ttggaaactg
    71161 tcttcttatt agcaaaacca gaatatagtc acgtgagttc cagtatttta aaagaagtac
    71221 tgcactttgg cggagatgtg agcagctact taccgccagt gatcaacgaa gctttagctg
    71281 gaaagcgtga atcaaatgaa agctaaacaa tggttgaaaa cagtactgat tatcatattt
    71341 ggaatgttga tcattggatt tgtagtagtt cccttgccgt attatgtaga atcaccggga
    71401 gccacgatcg atctgaaaga actaattacg gtcaatgata aggaagataa aggttctggg
    71461 tctttctctc ttacctctgt tggtatcagg caagctacag gtttcttagc tttaaaagct
    71521 aaaatgaccc cttttgaaga attgatcagt gaagaagaat tgactggtgg ggcgacaaat
    71581 gaagaatata atcaaatgca acagtattat atggattctt cccaaaatgc agcaatcgaa
    71641 caagcgttaa aacttgcaga caagccttat aaaatggaat tcaaaggcgt atatgtcatg
    71701 agtgtagaga aaacatcgaa tttctttggc aagctttcag ttggagatac agtaacaaaa
    71761 gtagacggga aaagctttca aagtacagaa gcatttatgg attatgtaaa aagccaaaaa
    71821 gttggacaaa caatcgaaat cagttatttg cataatggtg aagaaaaaac agcttctggt
    71881 gatctgatcg agttaccaac agataaaaag gcaggaatag gtatcacgct tactgaccat
    71941 accgagatcg aatcagatac agatgttcgt attaattctg gctctatcgg tgggccatca
    72001 gcgggattga tgttcacttt agaaatctat gaacaagtca ctggtaaaaa cttgcgacat
    72061 ggtaagcaaa ttgcaggaac tggaacgatc aacagtgaag gagaagttgg ccgaatcgga
    72121 ggaatcgata aaaaagtggc aagtgcggat aaagctggcg tagagatttt ctttgcacca
    72181 gatgatacga tttcagacga tgttaagaaa gaatatcctg aaataaaaac caactacgaa
    72241 gaagcaaaag ctgccgctaa aaaattgaat tcctcaatga aaatcgtacc agtaaaaaca
    72301 gtacaagaag cgcttgacta tctagagaaa atgaaatgaa actaaataat taaagagggg
    72361 ttgtgacacg agttctgtca caacccctct ttttcgtcaa aaatcttcac gataaaaata
    72421 aaaacaaaag aaaaaattga cgtaattaga tgttgaaggg acgattttgc cagagctcac
    72481 tgtttcttca attttaaatg aaaggagtaa tgaatgattt ttactggtca ttctttgaaa
    72541 aaagaacaat gatagaaaaa atcagcaaga aaatactagc ttcacccaaa ttgatcattt
    72601 ggatgtctat gatagttctt atcttttgta tcgcaagtgg ttttttatta tcaaatttgc
    72661 tattttatag agaaacagaa gagactgctg caaaagaaat actttcttcg tttagttcca
    72721 gtggagaaga tccatcagct gaaggaaacg atgtagaaga ggatgctcgt ccaaaggtca
    72781 tgtacaccga tatcaaagga agtgtgaagg agcctggtat ctattccttt tcttcagaag
    72841 aacgggtcta tgatgtacta aagcgtgcag gtggattatt agaagaagcg gatagcgatc
    72901 gaatcaactt ttctgcgaag atagaagatc agcaagtcct atatatccct gctgtaggtg
    72961 aagagctgcc agaacatctt gatcagttgg catcctcgga aggaaaacag cctacagcag
    73021 attccgagcc tcccaaaata aatatcaata cagccactcc atcagaactt cagcagattc
    73081 ctgggatcgg atcagtcaaa gcgcaagaaa tcattcgatt tagagaagaa aacggatcct
    73141 tccagaaagt ggaagacctg caggagattt ctggtatcgg tgaaaagaca gttgaaaaac
    73201 taaaaaactt cgttacaatt aaatagaatg attcaaaatc gactggcacg agcaataaat
    73261 ggacgctaat ggatactaag aataatccaa ttctaagagc ttggcaggac gaggaggtag
    73321 tatttttgga taggaaatag cttgattgtt cgcaaagaaa cattaaaaaa accaatgctg
    73381 aatgtctatc tccaaaataa aatatctggg attcatatta tgaatacggc tgtcagcggc
    73441 aataacagtc aagctctacg agaacgcttt gccaaagatg tacttagcta tacagcagat
    73501 aaagtattta ttctcattgg gacgaatgat ctagcagagc ataaacaact ttctaaagaa
    73561 acgtaccaaa aaatctgcag tggatgatag ttcagctgaa aaaagactat agttctgatc
    73621 atgctttctt tatcacgcca ccagcagtcg atgagacaaa acaaaaatat cggaataaca
    73681 agttgatcaa agaatatatc tctgttctca cagaagtagc aaaacgccat gattgtgaag
    73741 tatcgatttt tatacggaat ttcttgaaca aatggattcg aagaattttt ataatgggct
    73801 aatggatgac ggacttcatt tcggcagtga agggtaggat cttttgtcag acaggatgat
    73861 tcgttatatt taaagaatat tttgtttaag caatgagtac tttttaatca acttgaaaaa
    73921 acggaggaat ataaaacatg ttagaaaaat cttcaaaagc atgcgatacg aataaagaaa
    73981 aagttactga taagtcacat aatgaacgca ttccttggga ccagtacttt atggctcagg
    74041 cagtactgtt atctttacgt agtacgtgta cacgtttaga agtaggagcg acactcgttc
    74101 gagaaaaaag gatcattgct ggcggctata atggagcagt cagtggagat gtccactgca
    74161 tagatgaagg gtgttacgtc gtggatggac actgcttgcg aacgatccat gcagagatga
    74221 atgcactcct acagtgtgca aaacttggta tcccgacgga aggttcagaa atctatgtca
    74281 cacattttcc atgtttggcc tgtacaaagg ctttgttgca agctggtgtg aaagggatca
    74341 attatctcca tgactatcga aatgatcctt atgcccaagc gttgatcgaa caattaggtg
    74401 tatctgtaca ccaagttgct ttagactcac agcatttttc aaaacttcaa aatgaattaa
    74461 caggaaaaca tgtctagcgt tttagaaagg catgttcgaa atcggttgat ttttccggca
    74521 attacgtcga tgattatctg tttgttgtat tacactgaca attggggtta tcgtttgctt
    74581 cttgccggaa tttttttatg gttttcgcta aaagaaggac gttttatcgc gtacttgtgt
    74641 attttgtgta gcataacggt atccatttct tataggctac aagagtattc atttttagag
    74701 gaaaaaacaa catctgcgca aattactgta tttacagata cgattcgtgc aaatggtaat
    74761 tttttgacaa tggaaggaag gttatcagag aataaacaaa agctccagct ttcttatcaa
    74821 gtaaacacag aagcagaatt gaaaacatgg cttaacttcc gaggaaaggg aatagaattg
    74881 actgctgaag gcgagttcat ctctccagca aaaaagcgga atctttataa ttttgaccaa
    74941 gaagcttact tcaggaacca tagaatttct ggacggttcc aaattcaaaa gattgaacag
    75001 atcaccatgc aaaatcactg gcgaaactgg cttcagagaa aaagaggatc ttttatctcc
    75061 tttgtccaat ctgaatttcc gcaaaaaaca agtgtatata ttaattcttt attatggggc
    75121 tataaagatg caggattcag agaaccagaa gaaattttta gggagagtgg tttgctgcat
    75181 ctgttcagtc tatcgggtct acacatccaa ttttatttag ggtggctgta ttatttattt
    75241 cgacgtatcg gatggccact acacgtcagt attattccgt tgagtctact aactatctgt
    75301 tatgtttcta ttgcaggaag ttctatttct gttttgcgtg ctagtttgct gtttttattg
    75361 cgattgctag tcaaattgct gaataagcat tattccacca tggacttatt tgcagttgtc
    75421 ttttggcttc ttttactatt tgatcctcga tttctttttc atgcgggtgg acagcttagt
    75481 tttttcatga gttttttgtt tatcctgatt tcttttgatg gagattggtt gaaaaaaacg
    75541 gcctctcacg tcctgtttac tatgatcacg atgccgttga ttgtatggca tttttatgag
    75601 tggcctattt taggtagtct ttttacatta ctgattgcac cggtattcaa gtttcttttt
    75661 cttcctggtg tgttatttct cacactcttc aatcgctggc tgccggaaac tttacttttg
    75721 ctgatagaag agggattaat cttatttgag cgaataatcg atttttcttc agggtcgtct
    75781 ctcattatag gacgtttgcc ccttgtgcta tctgggatgt atattttcgg attactgatt
    75841 tgtatggata ggttgaaaga acaacctgtg aaacacttgt tttatgttgg tcttttttct
    75901 tttatttttt tgactttgcc atttttacgc ttttcttcaa cgatcgcttt tatcgatgtc
    75961 ggtcaaggag acagtatctt tttgcaaagt ccttttcgaa aagaaacgat tttgatcgat
    76021 actggaggtc agttacactt tgaaagagaa aagtgggcgc aaggtatgat acgtcctcct
    76081 gctgaaagaa atatcgttcc atatctaaaa ggtcagggga taagtgtaat cgataaactc
    76141 atcttgacac acgacgatac ggatcatgtg ggagaattac ccacgttatc tcagcatttt
    76201 actatcaaaa aaatttatat cggttggggc gctggacgaa atgagccatt acaaaggcat
    76261 ttatctgaag ctcaaaaaaa tggtactgag atcattgaaa tcaaacatgg ggacaggatc
    76321 agcggttatt atgatcttta tgtattgact ccttttgaaa agggagaggg aagaaatgaa
    76381 gattcgattg gtctatggat ggaatataac aataggcgct ttttattttt aggagatttg
    76441 aatcaagcaa tggaaaaaca attgcttttg atttatccta atctgaaagc cgatgtagtc
    76501 aaattaggtc atcacggtag ccgtacgtca agtaacacag attttctttc ccatattgaa
    76561 gcaaaacatg ggattatatc ctgcggcgta aataatcgtt atggtcaccc gcacagcgaa
    76621 gtattggaga cactagaaga aaatcagata aaaacatggc gaacggatca acaaggaatg
    76681 atcacctatc gctggcatcc agtttttcat cctcatgggc tagtggaaac aatgatagac
    76741 tagtaattct catctgctca tggtaggata atttttgaaa gtggtgagta atttgagtat
    76801 acaagcagag ttacaaaaaa tacgtaaaga aaaacttgca tcttgttact tgattttagg
    76861 aacagaaaag tttctccaag atcaagttcg gacagaaatt gtcaaaaaaa tccaattaga
    76921 gggcgaagat gacttaaatt ttttaagttt tgacatggaa aatgcaagtt tagatgaggt
    76981 agtagctgaa gcagagacgt tgccgttttt cggagatcaa cggttagtat tcgtagagaa
    77041 tccttatttt ttaacaggtg aaaaagtaaa caatggaatc gaacaaaata ctgatttatt
    77101 gacggcttat ttgaaagaac cattagaatc gactgtatta gtattctttg cgccatatga
    77161 aaagttggat gaacggaaaa aagtaacgaa acaattgaaa aaaacagcaa ttatcatcaa
    77221 tgtccaacag ttgaatgaaa aagaagtacg tcaatatctg atgaatacct tagagaattc
    77281 ctcaatcaaa atggaacgaa gtgcaattga tttattcttg aggttgaccg acttagattt
    77341 atccaaaatg atgagagagt tacagaaatt ggtcctttat ggacaaaatc aacagcaaat
    77401 cacggtaaga gaagtagaag aattagttcc taaaacgtta gaacataata tttttgacat
    77461 gacccaatat attttaaaag ggaagacgga acaagctttg cgtttatacg aagatttagt
    77521 tatgcaaggg gaagaaacaa tcaaaattaa tgcgattttg ctttctcaat tacgtttatt
    77581 tttacagaca aaatttcttg taaagattgg ttatcagcag gcaaatattg ctgaaacatt
    77641 gaaaatccat ccatatcgtg taaaacttgc catgcaggaa gtaaaaaaat tcgatgaaca
    77701 tttgctggta cagttgtttg atcaattagt tgagatggat tatcaaatca aaacgggaca
    77761 aatcgaaaaa gaattaagtt ttcaactatt cgttttgcgc acagggcagt tgttaagaaa
    77821 tcgataagaa gaaagacgag ggcaaagcat gcgggaaggt cgtttgtttt tgtccttttt
    77881 ttgacaaata aaaaaatcgg ccgaagccga ttcttttatt tagcgatttt tttgcttaaa
    77941 cgagatttgt cgcggttagc tttgtttttg tggattagac cttttgattc agccatatca
    78001 atagctttaa cagcttcttt atataacgca tctacgttgt cagcacctga agctacagca
    78061 tcttcaaatt ttttgattgc agtacgcata gcgcttgttt gagatgaatt tttcacatta
    78121 gcgttttcgc ttgtacgaac acgtttgatt gcagattcaa tgtttggcat tagtttcacc
    78181 tccgataact taagttctta cgcgtgttac cgcataattc aacattcatt attataccta
    78241 aaggcagcgt gctttgcaat atgaacatga caagtttttt tccttaacag tcttttatta
    78301 ggattttttt tcagtaaaaa cggatagtac aagctgaaaa aaatcaaaaa gacgctattg
    78361 tgggaggcaa tagcgtcaaa ccaaactaga tttttattta tctatttaaa caaagtttga
    78421 atgggaatgt ttggtactaa gttattatat aacaaagaga accgtttgca aagttttttt
    78481 tgaaaaggga tacgattccc tgttgttctt tgtttttcta ttaagaaact gcagttattt
    78541 tataaccagt atcctttgat cagtaaaggc tattctggtg taccgattat tttaatgtat
    78601 tcatcgatat tttttatcaa catttttttt atgaccaact ggttccgacg gttccatttg
    78661 ccacttactt ccagcacata tttatttagg ggcaaacgta agatatattt tgccaaatag
    78721 cgatctttaa gcaggccatt gatcacacgg tcctcaagct gcaagttgat cccagtcagc
    78781 atcattggct gttcttgtaa aacgtacgta tcaattaaaa gaccttcaaa agtttccaca
    78841 agcgtcttcc tttcttttca aagtaacctg aaaacaggca ctaattcttc cattttgata
    78901 ttcgttgaag tggatgcgat cattctttct tttgtccact gtaatctagt ataacaaaaa
    78961 agagcagaag agccaaaaag aaaaaagagc atcgaattct ataggaagtc tcattggcac
    79021 ggcctaaatt attacaaaac attgattaaa aaaagcccct gcatcgcagg agcatcccct
    79081 atatcgtttt aataggtcaa tcaaaa
//
LOCUS       DAKCAA010000005        77438 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000005 DAKCAA010000000
VERSION     DAKCAA010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 77438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.005"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..1087
                     /locus_tag="OUE31_000386"
     CDS             <1..1087
                     /locus_tag="OUE31_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCU0221422.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="OUE31_000387"
     CDS             complement(1305..2447)
                     /locus_tag="OUE31_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCU0221423.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="OUE31_000388"
     CDS             complement(2452..2637)
                     /locus_tag="OUE31_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCU0221424.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="OUE31_000389"
     CDS             complement(2991..3236)
                     /locus_tag="OUE31_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0221425.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="OUE31_000390"
     CDS             complement(3230..3631)
                     /locus_tag="OUE31_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCU0221426.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="OUE31_000391"
     CDS             complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="OUE31_000391"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HCU0221427.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5649..7415)
                     /locus_tag="OUE31_000392"
     CDS             complement(5649..7415)
                     /locus_tag="OUE31_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HCU0221428.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7428..8222)
                     /locus_tag="OUE31_000393"
     CDS             complement(7428..8222)
                     /locus_tag="OUE31_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCU0221429.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8232..9608)
                     /locus_tag="OUE31_000394"
     CDS             complement(8232..9608)
                     /locus_tag="OUE31_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0221430.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9728..10375)
                     /locus_tag="OUE31_000395"
     CDS             complement(9728..10375)
                     /locus_tag="OUE31_000395"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HCU0221431.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="OUE31_000396"
     CDS             complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="OUE31_000396"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HCU0221432.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="OUE31_000397"
     CDS             complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="OUE31_000397"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCU0221433.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13042..14673)
                     /locus_tag="OUE31_000398"
     CDS             complement(13042..14673)
                     /locus_tag="OUE31_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HCU0221434.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            14977..15648
                     /locus_tag="OUE31_000399"
     CDS             14977..15648
                     /locus_tag="OUE31_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCU0221435.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(16373..16708)
                     /locus_tag="OUE31_000400"
                     /pseudo
     CDS             complement(16373..16708)
                     /locus_tag="OUE31_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16805..17257)
                     /locus_tag="OUE31_000401"
     CDS             complement(16805..17257)
                     /locus_tag="OUE31_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221436.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(17264..17812)
                     /locus_tag="OUE31_000402"
     CDS             complement(17264..17812)
                     /locus_tag="OUE31_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCU0221437.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(17857..18189)
                     /locus_tag="OUE31_000403"
     CDS             complement(17857..18189)
                     /locus_tag="OUE31_000403"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221438.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(18203..18460)
                     /locus_tag="OUE31_000404"
     CDS             complement(18203..18460)
                     /locus_tag="OUE31_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221439.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(18655..19197)
                     /locus_tag="OUE31_000405"
     CDS             complement(18655..19197)
                     /locus_tag="OUE31_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221440.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(19218..20309)
                     /locus_tag="OUE31_000406"
     CDS             complement(19218..20309)
                     /locus_tag="OUE31_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCU0221441.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(20317..22527)
                     /locus_tag="OUE31_000407"
     CDS             complement(20317..22527)
                     /locus_tag="OUE31_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221442.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(22543..25071)
                     /locus_tag="OUE31_000408"
     CDS             complement(22543..25071)
                     /locus_tag="OUE31_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCU0221443.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(25123..25533)
                     /locus_tag="OUE31_000409"
     CDS             complement(25123..25533)
                     /locus_tag="OUE31_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221444.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(25546..25764)
                     /locus_tag="OUE31_000410"
     CDS             complement(25546..25764)
                     /locus_tag="OUE31_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221445.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(25761..26753)
                     /locus_tag="OUE31_000411"
     CDS             complement(25761..26753)
                     /locus_tag="OUE31_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCU0221446.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(26832..27743)
                     /locus_tag="OUE31_000412"
     CDS             complement(26832..27743)
                     /locus_tag="OUE31_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCU0221447.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(27762..28106)
                     /locus_tag="OUE31_000413"
     CDS             complement(27762..28106)
                     /locus_tag="OUE31_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221448.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(28126..28682)
                     /locus_tag="OUE31_000414"
                     /pseudo
     CDS             complement(28126..28682)
                     /locus_tag="OUE31_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28763..29263)
                     /locus_tag="OUE31_000415"
     CDS             complement(28763..29263)
                     /locus_tag="OUE31_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221449.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(29264..29809)
                     /locus_tag="OUE31_000416"
     CDS             complement(29264..29809)
                     /locus_tag="OUE31_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221450.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(29806..31062)
                     /locus_tag="OUE31_000417"
     CDS             complement(29806..31062)
                     /locus_tag="OUE31_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCU0221451.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(31423..31734)
                     /locus_tag="OUE31_000418"
     CDS             complement(31423..31734)
                     /locus_tag="OUE31_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221452.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(31757..33067)
                     /locus_tag="OUE31_000419"
     CDS             complement(31757..33067)
                     /locus_tag="OUE31_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HCU0221453.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(33681..34133)
                     /locus_tag="OUE31_000420"
     CDS             complement(33681..34133)
                     /locus_tag="OUE31_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221454.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(34135..34500)
                     /locus_tag="OUE31_000421"
     CDS             complement(34135..34500)
                     /locus_tag="OUE31_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221455.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(34599..38882)
                     /locus_tag="OUE31_000422"
     CDS             complement(34599..38882)
                     /locus_tag="OUE31_000422"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HCU0221456.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(39029..39268)
                     /locus_tag="OUE31_000423"
     CDS             complement(39029..39268)
                     /locus_tag="OUE31_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221457.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(39358..39630)
                     /locus_tag="OUE31_000424"
     CDS             complement(39358..39630)
                     /locus_tag="OUE31_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221458.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(39713..39964)
                     /locus_tag="OUE31_000425"
     CDS             complement(39713..39964)
                     /locus_tag="OUE31_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221459.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(40960..41871)
                     /locus_tag="OUE31_000426"
     CDS             complement(40960..41871)
                     /locus_tag="OUE31_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0221460.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(42067..43902)
                     /gene="lepA"
                     /locus_tag="OUE31_000427"
     CDS             complement(42067..43902)
                     /gene="lepA"
                     /locus_tag="OUE31_000427"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HCU0221461.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            44049..45269
                     /locus_tag="OUE31_000428"
     CDS             44049..45269
                     /locus_tag="OUE31_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0221462.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            45289..45783
                     /locus_tag="OUE31_000429"
     CDS             45289..45783
                     /locus_tag="OUE31_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCU0221463.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            45761..46447
                     /locus_tag="OUE31_000430"
     CDS             45761..46447
                     /locus_tag="OUE31_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221464.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(46598..49207)
                     /gene="clpB"
                     /locus_tag="OUE31_000431"
     CDS             complement(46598..49207)
                     /gene="clpB"
                     /locus_tag="OUE31_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HCU0221465.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(49458..50504)
                     /locus_tag="OUE31_000432"
     CDS             complement(49458..50504)
                     /locus_tag="OUE31_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HCU0221466.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(50515..50787)
                     /locus_tag="OUE31_000433"
     CDS             complement(50515..50787)
                     /locus_tag="OUE31_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HCU0221467.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(50822..51730)
                     /locus_tag="OUE31_000434"
     CDS             complement(50822..51730)
                     /locus_tag="OUE31_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HCU0221468.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(51862..53094)
                     /gene="pepT"
                     /locus_tag="OUE31_000435"
     CDS             complement(51862..53094)
                     /gene="pepT"
                     /locus_tag="OUE31_000435"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HCU0221469.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(53109..54230)
                     /locus_tag="OUE31_000436"
     CDS             complement(53109..54230)
                     /locus_tag="OUE31_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HCU0221470.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(54227..54928)
                     /locus_tag="OUE31_000437"
     CDS             complement(54227..54928)
                     /locus_tag="OUE31_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HCU0221471.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(55072..55512)
                     /locus_tag="OUE31_000438"
     CDS             complement(55072..55512)
                     /locus_tag="OUE31_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221472.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGPSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(55641..56567)
                     /gene="dnaI"
                     /locus_tag="OUE31_000439"
     CDS             complement(55641..56567)
                     /gene="dnaI"
                     /locus_tag="OUE31_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HCU0221473.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(56567..57940)
                     /locus_tag="OUE31_000440"
     CDS             complement(56567..57940)
                     /locus_tag="OUE31_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCU0221474.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(57963..58454)
                     /gene="nrdR"
                     /locus_tag="OUE31_000441"
     CDS             complement(57963..58454)
                     /gene="nrdR"
                     /locus_tag="OUE31_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HCU0221475.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(58766..59098)
                     /locus_tag="OUE31_000442"
     CDS             complement(58766..59098)
                     /locus_tag="OUE31_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCU0221476.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(59150..59779)
                     /locus_tag="OUE31_000443"
     CDS             complement(59150..59779)
                     /locus_tag="OUE31_000443"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HCU0221477.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            complement(59743..60579)
                     /gene="mutM"
                     /locus_tag="OUE31_000444"
     CDS             complement(59743..60579)
                     /gene="mutM"
                     /locus_tag="OUE31_000444"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HCU0221478.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(60624..63269)
                     /gene="polA"
                     /locus_tag="OUE31_000445"
     CDS             complement(60624..63269)
                     /gene="polA"
                     /locus_tag="OUE31_000445"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HCU0221479.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(63395..64078)
                     /locus_tag="OUE31_000446"
     CDS             complement(63395..64078)
                     /locus_tag="OUE31_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HCU0221480.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(64071..64556)
                     /locus_tag="OUE31_000447"
     CDS             complement(64071..64556)
                     /locus_tag="OUE31_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HCU0221481.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            complement(64863..66197)
                     /locus_tag="OUE31_000448"
     CDS             complement(64863..66197)
                     /locus_tag="OUE31_000448"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HCU0221482.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            complement(66328..67089)
                     /locus_tag="OUE31_000449"
     CDS             complement(66328..67089)
                     /locus_tag="OUE31_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCU0221483.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            complement(67105..67587)
                     /locus_tag="OUE31_000450"
     CDS             complement(67105..67587)
                     /locus_tag="OUE31_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HCU0221484.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            complement(67607..69787)
                     /locus_tag="OUE31_000451"
     CDS             complement(67607..69787)
                     /locus_tag="OUE31_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HCU0221485.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            complement(69931..70662)
                     /locus_tag="OUE31_000452"
     CDS             complement(69931..70662)
                     /locus_tag="OUE31_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HCU0221486.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            complement(70731..71672)
                     /locus_tag="OUE31_000453"
     CDS             complement(70731..71672)
                     /locus_tag="OUE31_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HCU0221487.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            complement(71852..72220)
                     /locus_tag="OUE31_000454"
     CDS             complement(71852..72220)
                     /locus_tag="OUE31_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HCU0221488.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            complement(72831..74222)
                     /locus_tag="OUE31_000455"
     CDS             complement(72831..74222)
                     /locus_tag="OUE31_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HCU0221489.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(74435..74821)
                     /locus_tag="OUE31_000456"
     CDS             complement(74435..74821)
                     /locus_tag="OUE31_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HCU0221490.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(74877..75500)
                     /locus_tag="OUE31_000457"
     CDS             complement(74877..75500)
                     /locus_tag="OUE31_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HCU0221491.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(75564..76232)
                     /locus_tag="OUE31_000458"
     CDS             complement(75564..76232)
                     /locus_tag="OUE31_000458"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCU0221492.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(76244..76684)
                     /locus_tag="OUE31_000459"
     CDS             complement(76244..76684)
                     /locus_tag="OUE31_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221493.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(76743..77414)
                     /locus_tag="OUE31_000460"
     CDS             complement(76743..77414)
                     /locus_tag="OUE31_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCU0221494.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
BASE COUNT        22645 a        16263 c        12110 g        26420 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaatacaac aatcagaaag cccctttttt tcgaaaaaac tagaaaaaaa acataaaaat
     3721 atttatcatt ctttaaacag aaaatctttc tataaaaaac aaaaaaaaac gattaggcta
     3781 ggctaatcgt tttttgaaca ttcttaaaaa atccaaatta ttttttataa ctgaaattgg
     3841 gtattgatga ccatcgtttc tgtagatagt aagcaatcat tttaggtttt ctatctctag
     3901 taaagattcc tttcttattt ccttgcactc ttaaaatccc ttgacttgtt gcaaaatctg
     3961 caaaattcca cacttgttca ccaacaaaat tttcacatgt atctattact tcgtgatttg
     4021 cttcgtaata agccacttga tactcttctg taaacattgt tggtactgta tcatgaaatc
     4081 cagctactgt atctgctcca tattctgtaa acattattgg cgtatcagga catctttcca
     4141 tccatccatc tagctctttt ttcaacagat attttgcatg tgccagatcc cctcccgaaa
     4201 cataccaacc ataataacga tttaaacata aaacatcgac aatatctcct accttacaaa
     4261 catctggcgt tgattttaga taagtaacga ttgttacagg tcttttctgc ggatcaagtt
     4321 ctttagttaa ttcaactaaa ggttcaaaat attctttagc accttcggaa tccgaatctg
     4381 gttcatttgc aatagaccac attacaacac ttgggtggtt cttgtcgcgt tctatcaatt
     4441 ccttgatcac cgttttatga gaattttctg ttcgtatctc tttccacgta ttatgttttt
     4501 ccacattatc atctaataaa gtggccatga aatttaaatg taaccctact gcaggtactt
     4561 catcaataac tacaatacct tctcgatctg ctaatcgcat aatttcttct gagtaaggat
     4621 aatgtgatgt tctaaaagaa ttagcaccta tccatttcat taaattaaaa tctttaatat
     4681 ttacagcctc attcaaacca cgtccattaa catacgaatc ctcatgctta ccaaatcctt
     4741 taaaataaaa aggtttatta ttaatcaaaa atttgccatt ggtaacctga acactgcgaa
     4801 taccaaattc ttctgtatag gtatcgatca ctttattatc atcaattaaa ctaattttca
     4861 tactatataa ataagcgtct agaggttccc aaaaaattgg attcttaagc tgaatcattc
     4921 ctttctttcc ttcagcttca gctacaagtt gagcctcttc gtcatatatc gctattaaga
     4981 tttttccggt ccattctgta tcgatattga attctacact tgcatccaaa tcagttattc
     5041 ttgtattaat agtaatatca cttatatagt ctttcggagt tgtatataac ttaacaggtc
     5101 tatgaatacc tgcataattg aagaaatcaa aattaactaa gttttccttt tttatatccc
     5161 cattttcctg tactgtttcc ttcataatcc ccacaggtaa agtactatcg tcaataatat
     5221 tgtttacagc aactgtaatt cgattattcc cgtcttttac aaaccgatta atttcagact
     5281 caaatggtgt aaacccacct ttgtgttgag taataaactt tccattcaaa aaaacttttg
     5341 cttcatgtgt tgcagatcca aaacgaagaa ctaatctttc ttctaataat cttttaggaa
     5401 gagtcacttc tttttcatac cacacccatc caacatgatt tctaatgttc tctgtttcaa
     5461 ataaatcatt ataagaagag ggaactgaaa tcggataact ctctttttca tttattggtt
     5521 ctaaagcaag ttcttcctgt aagtcatcat ttgtatctaa tttaaatctc cagagaccgc
     5581 ttaagtcaat tacttgcctc gtctctgtca taatgggata caacatataa accactccta
     5641 tctaaatatt aaataaatgt atcctttaaa ccacaataag catctattgg acttactccc
     5701 ttaaattcag aaagacccat tagtttgtcc accaatattt ctaaagtttc ttgttttcca
     5761 tcataagtat taatataagt ctttacttga ggtacatcag ccaaatgaaa cggacactgt
     5821 acagatacaa aaattgttgg aatttcatga atgtaaaacg gtatatccgg agttccttta
     5881 cttgctggcc agacaattcg ttgaactgtg cctggattaa cattagctat attaatgatc
     5941 aagtcatatt ttttagttaa atttttaatt ggtctcttag cagcatatat tccagctata
     6001 tttttaattt tttcttcttg cgataatcct ttcaattctt cttcaggtga aatgtatttt
     6061 tcaacttcaa atccttttgc tgacaaaatc tgtttcaata aatcaatggc ttgaggtcta
     6121 tttccagcaa ctacttcacc aaacccacct tttaccccat gtacatctac tagtaaaatc
     6181 cttttatatt tttctggtac aataggccaa atatcttgtt tatctttaac taatgtaatt
     6241 gcttggtcag ccacctcttt aaaaattgat ttattttcaa ttaaaccaat tttttccaga
     6301 gcttcttgct taggtaataa aatttgttct tttgcttttt tgtgtaatcc caatttagct
     6361 tttaacccta aaattctttt taaggcatct aataaccgat catcagtgat aattccttta
     6421 cgatagcctt ccatcatata attaaagtct tcatctggat cattaaaaaa tagaaataga
     6481 tcacatccag ctgcaataga agtgggcaat aattctgatc gtttcattgc cccagtcatt
     6541 cctaacatat gactagcatc agtaactact aatccattaa atccgagttt tcctctaagt
     6601 aagtcagtga ttaattcttt tgataaagtt gcaggaagta aatcttcatc tttcagatca
     6661 ggattaaaat gttttgaata agctggcata tggatatgac ctgccataat tgaaggtaat
     6721 ccagcttcta ttaagcctga gtatactttt ccaaaagaat tatcccattc ttccgtacct
     6781 aaactattaa tactaaaaga tagatgctga tctcgttcgt caataccgtc accagggaaa
     6841 tgtttagctg caggcaaaat tccactctcc tgaatacctt tcatataagc taaactaagt
     6901 tctaaaactt tatcagggtt ttgtccaaaa gatcgactag aaatgatagg atttctccaa
     6961 tttctattaa tatctacaat aggagcaaaa ctccagttac atccaatagc cgatgcttca
     7021 atcccagaaa ctctccctaa ttcataagca tatttcgcat catttgttgc accaattttt
     7081 acttctacac caacttcagt accatctgta caagctccgt taccacctgc ttccgtatta
     7141 gcagcaatta atagaggaat tttactttct gtttgtaaga tatagttttg atcatatacc
     7201 tcatcagcag ttcctggatt atatcgtaca gctccaatat ggtactgatt gaccatatta
     7261 ctcaagtaat ttttatcacg actagatccc atattaacaa acaattgacc tattttttct
     7321 tccaaagtca tagaatcaat cgtctcttca atccaagaaa tagcatcttc atctaaatta
     7381 tatggttttt ttcgtaaatc tacttttata gtcattttct ttctcctcta cttattagta
     7441 agatttttcc aaaaagtatc tatatatttt tgttcaatat ctacataatc tcccgataaa
     7501 catttaaata aaacatcagt tcttaagttt tcccatgatt ctttttcttt attgaccaaa
     7561 ataggataaa agaaaacttt atttttattt gcagcttcta gatcaccagg agaatcacca
     7621 atcattaata tcttatccaa atcacaacca ttttcaatta cacttcgaat aatatcttct
     7681 ttttttcctt tatcttgaca acacagttca tcaactaatg ataataattc atgtctttcc
     7741 cattcttctt gaacagcttc cttattagct gagcttacaa taattatctt cccatatttt
     7801 ttcagagctt ttatagtatc tctagcactt aaaaagggtt tatctaatcc ttttgcttga
     7861 ctaatctgtt gattgacttc ttccgaccat tttaaagctt ttaataaatc ctctgactga
     7921 gaatattcta tttccctctt caaagatgga ttagacaatt cttttgttag agatacccag
     7981 tgctttaatc gattaatcga tgttacatca tttttttcta atgttttaac taaacctaaa
     8041 aatctgttta ttccacgagt ctctgaatat aaattaatat tattccaatc ctgtaggaat
     8101 ttttctctat gatgaacatc aaaaatctct gcagcaattg gtccgaaaaa gagattgtgt
     8161 ttataagtca tcgtatccat aacacagcca tctgaatcaa tacaaaatat ccaattattc
     8221 atatttctct cctatttatg tttttgtttt aaaagctcgc aattttctaa gactttatct
     8281 ttagataatg gataaaggaa aaataaaatt aatcctacaa tcagaaaaca aattgatgga
     8341 attaatgttg aagcgttata taacttttct aaaacatctc ccgtttgtac atttgctaaa
     8401 gagtcatagc ctataataga aagagtccaa cctccgacgc ctccagctag agcttgacct
     8461 atttttctag caaaagaata taccgcatat acggtcccat cttctctttg atcagacttt
     8521 acttcttgat catcaataac atcagtaata tttgcccaaa taacagtatt aaacacaccc
     8581 aaacccatat agccaaccga actaagaatt aagaatacat acatattact agcttttatc
     8641 aaaaataaga tcaaatatac tattgctgaa aagaacattc ctactgatgc cagttctttt
     8701 tttccatatt ttttacttaa aaacaaagtt aaaggcgaaa caactattaa aaccaaaata
     8761 ggattgataa aattcattaa aactattccc tgtgcatcat tatagtaatc aggaaataca
     8821 taattattca tactcataat taataattga gcaaggagta agaaaatagc cgcaccaatt
     8881 atagaaagta atgccctatt tttaactaac ccttttaaag attttaacaa tgaaactttg
     8941 tattgagatt ggtcaattct tactcgttca gtagttagtt tataacatat taaataacaa
     9001 ataagtgcac atatcgaaaa tattcccgca acaattgtaa aagttgatcc accacgaact
     9061 atttgagcgc ctgaatcatc tcttgtataa ataaataatg gtgttaatac accaatgacc
     9121 aaacttgcta aagtagctcc aacatttcgg aatgtcgata gcattgttct ttcttctgta
     9181 atagaagtaa tagctgatgc cattgatcca taaggaatat ttatagatgt gtaaaaaata
     9241 ctcccccata atatatacgt aacatacatg tatactacct taacgctcat agaagctgaa
     9301 atcatagaag tttgatacat taaaaaactt gctaaagcga ctggaccact cattcttaaa
     9361 atccacggtt taaacttacc ctgcttagtt gctttcgatc tatcaacaat acgccccata
     9421 gttacatcag taactgcatc gataaatctt gctactaaaa ataatgttcc aacggcagct
     9481 ccgcttatcc ccaatacttt tgtataaaag atcattaaaa aagaactagc aaaaatgaaa
     9541 gtaaaatcgt ttccaaaatc tccaaacata tatcctattt tgtctcttat accaaatttt
     9601 ctttccatac aattctctcc cttctgttgt taagcgtttt cattctgatg aaagtacgta
     9661 ctatactctg aagcgtaaag agtcagtatt tattttttac atttcagagt attatttgtt
     9721 ttttctccta ataattcttt atctcataaa acttatctat atatttacta gctactcgac
     9781 ttacttcttc aaaatcacct ttttcaacag aagccaataa attcccacct acaccaactg
     9841 caacaactcc tacttcaaac caatcttcta agttctctat acttactccg ccagtaggca
     9901 ttatatttac gtgtggtaat ggagcttgat aggcttttac aatggatgga ccaaaagcag
     9961 aacctgggaa tagtttaatg atatctacgc cagcagtaag tgcctccttt atctcagtaa
    10021 ttgtcataca acctggtaaa taaggaattt gatataaatt acaaatctca gctgtttgtc
    10081 gatcaaaaga tggactaacg atatattctg ccccagccat aattgcgata cgagcagtaa
    10141 acgcatctaa aaccgtaccg gctccgatta ttacatcttt ttgatcagca tattttttag
    10201 caatttcttt gattatttct tcagcattag gaactgtaaa agttagttca atccctttaa
    10261 ttccacccgc aataattgaa tttattgctt taatggcctc atccttattt ttcccacgta
    10321 caaccgcaat gactccagcc gcttctaact tacttaaaat ttctactttt ttcatatcta
    10381 tctccttcct ttatggatac atactttgtc tagctgtact aacttacaaa gaataaattt
    10441 aagcttttat ttcaagtatt attttctact tccgatttca aaaaaattaa aataattata
    10501 cgcattacga taacaaatat tctccactat ctgactaaga tacatttcat catctggaat
    10561 tcggcctgct ttaacccact cgcttagtaa ttgacataat actcgacgaa aatactcatg
    10621 gcgaggatag cttagaaaac ttcgagaatc agtcaacata cctgtaaaat tcgacaacaa
    10681 actttgttgt gccatcgtag tcaactgttg acgcattcct tcagctgtat cattgaacca
    10741 ccaagcacat cccaattgga ttttttgaat cataccccct tggaagcttt gcattgctgt
    10801 tgctagtgga agccaatcag ttggatttaa tgaatataaa attgtttttg gtaagcaccc
    10861 actcttttca gcggtatcga acaatgctac aacattttgt gtcaaactag cttgatcccc
    10921 catcgaatca ccaccgacat ctactccaat ttgttccttt aatatacttg aattatttct
    10981 taaagcattt aaatgcattt gcatcgtcca accatatctt gtatactcag acatcaaatg
    11041 taattgaata cctgtaacaa attgtgcaat ttctgataaa tggaaatccg tttttcctgc
    11101 taaagctttt attaacagat tgtcgagtat tttttcatct gctatttcat aaaaataagt
    11161 attcaaaccg tgatctgcta atcgacagcc aatttgatga aaatgatcca ctcgttggct
    11221 caatgcttgc ttcaacccat taaagtcttt gattggtata gccgctgttt gactaagttt
    11281 taaaatatag ttcgaaaagc ctgatgattt gatactccag accttatctg gacggaaagt
    11341 aggtaatacc ttgaaagaat tatcctgttt agaaagctca gtatgatacc acaagtcatc
    11401 tgtaggatca tccgttgtac agatggcttt cacatccatc atctccaaca attctttcgg
    11461 gcgataggaa tccgtttgaa ttttttcgtt agcacgtcgc caaatttctg gtgcattctt
    11521 ctcagaaatt gtcaaatcaa tatcaaagta acgttgtaat tccaaatgag accattcaaa
    11581 aataggatta cctggcgcct tctccactgt ttttacaaaa gctaaaaatt tttcataatc
    11641 atcacctgga ccactgatca actcttcttc tataccatta gctcgcatca atcgccattt
    11701 ataatgatct ccagctcctt tatcatttaa ccatacctga gtcaaattct tgtattgctt
    11761 attttctagc aaatatgctg ggtctaaatg acaatgatag tcgataattg gttggtgttt
    11821 tgcaaattta tgaaaaagtc ttttagctat ttcattctct aataaaaagt tcttatctaa
    11881 aaacatattt aaacactcct ttccttccgt tagtttttag aagagaaaat ttttcctcta
    11941 aataaactcc cttatataat tatttactcg cccccttttc aagcgcttcc caaataccat
    12001 ttaaataaac tgcacctaga gctcggtcat ataatccata accaggtcta ccggtttctc
    12061 cccaaatcat ccgaccatga tctggacgaa tatagccatt aaatccatta tcgtacattg
    12121 tttttaatat cttatacata tctagagaac catattctga tttatgcggc gcttcgtaaa
    12181 aatcgagtcc attgtcactt aaatatttga tattacgaac atgtgcaaaa ggaatccgat
    12241 cccgttgaca aaattcagat agaatttcat agacatcatt atctggtcgt tctgcaatac
    12301 ttccagtaca taatgtaata ccattagaag gagaatccac tacattacac aaccaatcta
    12361 aatcgtcacg atttttaaca atacgaggta atccgaaaat ggaatatggt ggatcatctg
    12421 ggtgaactgc cattttaatc ccaacttctt cacatgtcgg gataattgct ttgagaaaat
    12481 atgcaaagtt ctctcgtaat ttctcttcat caacttcttt ataggcttct aataattgct
    12541 taatttgtga taaccgatga ggttcccaac ccggcaattc aaaattatta gtagaatttt
    12601 ctacttctct aataatttcc tccggatcag tagggatatt ttttgaaata taggctaacg
    12661 tagaagaccc atcatctaaa cgataatcca aatccgattt tacccaatca aatactggca
    12721 taaaattata acagataacc tcaatcccaa attctgccaa attgcgaatc gtctgtttat
    12781 aattctcaat gtattgatct cgtgttggta aaccaatttt gatatcatca tgaacattaa
    12841 cactctcaat aactttcaag gtaagtccat tggcttcgac ttcatctttt aaagatttaa
    12901 ttcgttctct cggccaaacc tctccggctg gtatatccat taatgttcca acaattcctt
    12961 tcattgctgg gatctgacga atttcttgta gtgagatttt ttcttcattt gccccatacc
    13021 atctaaaagt catttccata gttactttcc tccaacttct gttatatatt tattgattgt
    13081 tttacgaact gcttgaggac ctactagcat ttcgcaaaag attttttcag ttttctttcc
    13141 taccccaact tgatataaat ctaaaccaaa gatttcttta ttttctaaaa tttcctgtac
    13201 cgcacaatga atctttgaag gatcttgttc acctaatttc aatactgata atttatcctg
    13261 caactctacc aataacggat caggacttgg cacaaaattt tccccttgat catcgactgc
    13321 cagtaaataa cgtaaccaag cagcaatagc gataggaata aatgttagat tttctgcatt
    13381 tccgtctttt tcgacatact ttttaattgt ttcaccatag cgaatcgcta ctttttgaga
    13441 agtatctgtt gcaattcgtt gtggtgtatc tggaatatag ggattaggca aacgtttatt
    13501 aattacttca tcaataaatt gttttggatc aataatgcct ggattttcaa ctactggtaa
    13561 accttctaaa taacctattc ctttgattaa accaaccaaa tcatcatcct gcatctctgc
    13621 tgaaattgat tgatatccta gcagacaacc tgttactgcc aaagcagtat gaagtggatt
    13681 caagcttgtc gtaaccttca tgatgtctgc tttatcaacc gtctctctat ctgtcataat
    13741 cacaccagcc ttttccaatt taggccggcc atttggaaaa ctatcttcaa taactaaata
    13801 atgaactacc tcagtattag tgaaagcagc aatattggta tgtttttttg tgtgaatgat
    13861 atctaaatcc tcgagcccca tcatcaatag atcttccttt acattctctg aaggatttgg
    13921 cgtaattcga tcaatcatac tccaaggaaa agtcactttt tctttatcct ttaaataagc
    13981 aataaatttt tcagaaacat atccttcttt ttgccaagct tctgcaatcg taaaaatact
    14041 atcttgaaaa cgttgaccat tctgtgagaa attatcagta gaaaccatcg caatcggcaa
    14101 ctctccagca ttaaatctgc tatataacaa ggatgttaca atactcatcg tatgttgagg
    14161 attgctaggt ccagatttga tatcagcttt gactaccgaa aagaattgcc ctttagaatc
    14221 ttttaaactg taaccttttt cagtaatagt aaacgttgta aactgtaatt taggatcttc
    14281 aaaatattta accactcttt gatagtccgc tatattcttc ggattgcaat ataaactatc
    14341 agccgttact gccaaaagtc tttttttgag ttcaccatct ccactcataa caatttccaa
    14401 aatgtcattg ttatagtcat gataagcttt ttccactact tcttcatcaa atgtttcaca
    14461 cacaactact cctgtttcta attcattttg atctgctaag cattgagcaa tttctgcatg
    14521 aaatcctcga taaagatttc ctccaccaaa atgaagccat actggatgtt gctggccttc
    14581 ttgcttaact tctttgacat caaaacacgg cagtagaatc tgcatttcat tgaattcttc
    14641 gatagaattt tgccaatttt taatcgaaac cataattaac ctcctcaaac tgatatgtta
    14701 gttttgatac attttatatt ttaaaaccca ttgtaaccgt tgtcaatata aaaagggaat
    14761 aaacttgctt ttttctacca tatcagaatg attgtatttt ttattcagaa aaataaaata
    14821 ctccttcttt ttggactgat tttatcgaaa cttatttttt ctttttttca tgtattcttt
    14881 tatttttata actagtgtat tacttcaaaa tttgatatta tatggcatga acagaattaa
    14941 aatatcagtt aaaataaaag ttaaggagca ttgtgtatga caattaaaac tagtctccaa
    15001 aatcaagctt accaatctat tcgccgacaa attatctatg ctgacttaga acctggaaaa
    15061 aaagtatcag aaaaaaaatt agaagaaaca ctttctattg gtcgtacacc aatacgtgaa
    15121 gcactgattc aactccgaca acaaggtctt gttgatacaa ttcctcaaag cggaaattat
    15181 atctcattaa ttgatttaga ttcggccaaa aatgctcgat ttgtcagaga acatttggaa
    15241 cgacaaatta tgttagagtg ttgtgccaaa atgaataacc aaaaaaaacg gattttagaa
    15301 actataattt cagaacaaga aaaagctgtt agtcaaaaaa atgctcgtag tttttttcat
    15361 aatgataatt tattccataa agcttgtttt gaaattgcag agcgagaaga agtatggcaa
    15421 tggttagaaa ataacaatac acacttagaa cgatttcgat ggctacgagt aaaaacggaa
    15481 ggattaaagt gggaaaaaat tatggaacaa cattatcaac tatttgaggc attaacaaaa
    15541 caagatccag aagaagctaa ctttctaaca tcgttgcatc ttcatttaat gcttaatgag
    15601 caaaatattg ttttagctac tcatccaaaa tatttcaaaa atatataact tttaactctt
    15661 tttaaattaa atggttgttc tgatcagaaa aatatcgctt gttttcttat tatgtaatat
    15721 atttcataaa ctattctgca taacaactat tgtttgtact ttttacattg gataactaat
    15781 tatgactgct gataactttt gatattaaac tagtatctcc aatacaaata aaaaatagat
    15841 atcttgttca tcaaaattag ttcgtggata cttaccttca tttacatcat tcagcggttt
    15901 cccattttct tttattctat tatttcattt tctaatagac ttggcttcat ttcgcaatac
    15961 tttttttcaa taggcatcaa attggtgttg tttagatatt tagttgtagt tttgtgacat
    16021 gataagtatg ctcctttttc tcttttccac taatacaacg atcaaagggt gcttttttca
    16081 aaaaactaga aaaatcaaaa taagattcgt attttgattc tatatatcct gtttcaacta
    16141 catcttatat ttcacaatag aataaatagc cttttgcata gctgcttaac ttataagaaa
    16201 ttgcaattta cttcttcaaa gtgaaaacga atatgagtaa aataaaatta ttcttcttac
    16261 agataattaa aaatagcgcg taacaaaaat cggcattcaa tcacataatt aggattgatg
    16321 ccgattactt atattctacg tatagtttta gtattcttat tttttatcac cagtaaccaa
    16381 ttgagaacag ccctaaagca gaatagtctt ttatctcaaa acgcttaatt tcaggcttag
    16441 gaatatgaat aatcttttga gtatattctt tctcttttaa tcttactgaa gaaataccac
    16501 tgcctatctt ttttacaaat atttcatttg gtgtacagac taataaaaca atatttgtaa
    16561 tcaatccttg cactaaagaa ttaaaaggaa gactatttaa aacagggtgt gcataactat
    16621 aacatgtgaa gtagttattt tgaactttaa cttttaaaaa ctttaaaaat aatcttattt
    16681 gttcttctaa acaatcatct atactcatat aatcactcca ctaattaatc tccccaaaaa
    16741 gacacagcat taagagatat accaacacaa cagtgcaaat aactctacat cttccttcgc
    16801 aaccttattt caataaacca taaaaattat tttttaatag aaactgaaaa ttaaaactag
    16861 aaaaagtagt tttaccgaat gtaagagcat catcaccatc aatatagaaa tacattcttt
    16921 tccagttaca tttaattttt aaacaaaatt ctccccaaaa aggaactttt tctagtgaaa
    16981 acttggtaat ctctttgtaa ttaattcttg ttaaagaata attaaacact tcatttttac
    17041 ttgttatttt ttcattgact ataactagtt catctggtaa aaaaattaac caacaaacat
    17101 cgacaaacag taaatgatat aatccatttc cacctccaag catattcaat actggtgaac
    17161 atgccttaga aacacgaata tagttatggt ttaaatagat attttcttta aacattgctt
    17221 gtttaaaagc catatgctct tgttctaaac ttttcataaa cttttactct aatgcacagc
    17281 tagcagcagc tgctgcaatt cctgctacaa tatttacctt agctaactct ttagctgcag
    17341 cttttcctaa ttgtttttct gcaattttta ataataaatc cgcagctttt tcaaaattaa
    17401 aagcttttaa tgcttcaata aaatctccct gcgtacctat agcccaagcc actcctcctc
    17461 caggaagaga attaatggct acacatccag catatcgttt ccaatcaact ttctccattc
    17521 taggaacaat aatatgttca taaaagactc ttgctgctct tccttgttcg ttatcttgac
    17581 tgattcgttc acgaatagca ccaaaatcct ttatatggta tacaccatgt tcgtctaaaa
    17641 aaccaactgt atcaaaataa aaagttaatt catctactaa tttattcttt atttctaaat
    17701 caactgtatt cactttttct gtggcataca cacttgttcc agtactaaca aaagtactta
    17761 aacctaataa gaaaacacct aaaacaccaa atattttaat tattcttttc ataatttctc
    17821 ctccataaaa aataagttac tttttaaata tcttgtttat gaattcattc cccaaaggcc
    17881 ttttaagatt gatacagcag tccgttcact tcttttagac ttgtcataca agtcttttaa
    17941 atgatcccat atcagactag tttgtctatc tagcttcaat ccattaaacg ctaatgaacg
    18001 gttcattttt tctattactt tagataaagc tacagaaatt tttatacctt cacaacgcgc
    18061 atcttggatt tcaataatag tatcatcaat tagtttttga atttcttgcc tatcaacata
    18121 ttcaatctta gaaagagaat cttttaaagc tactaatgat tcaacgattt cttttttctc
    18181 ttcagacatt ttcttcctcc ttctagtgac ccgtaaagcc atgtagagca gagtccattg
    18241 aaccagtaat tacactatct acaacgccat tccaatttac tctacatttt ccatttttca
    18301 gatttgtcgg tccatacgga tagccttttt gacattcaat gttcggatta taccagatag
    18361 gattatacca ttcagccgca gaagcagatt cagtcgatac aaacaatccc acaccaacaa
    18421 atccaataca catcacacta tagccaatta gttttttcat ctcgtatcca tctcctaaaa
    18481 aatagaatag ttcttatagt tattcataag acatattttt tccgtttttg ttttatcctt
    18541 tctgtcctat aacaactttt ttcaagtaaa gaatgacata gtttttctta aaaaaacagt
    18601 ctgttttttt ctatttcttc ggtgtataat aaatatgagt gttcattttt tattttaata
    18661 cgcactccgt acataataaa tcttgatcgc atcaatcttt tgagcttctt gatctacttt
    18721 caattgaagt aatacaaatt gagtaacctt attcattgtt tcttctccaa ataacaaata
    18781 ttgatccgga ttctctatat cttgtgtcac ctggtaaagt ttcccagttg ttttcatttg
    18841 tacatgcggg tctacatcaa tactattgtc tttaatacaa cgatctgtca tatagtccct
    18901 cacagcttga ttgcgtttat aaacatctgt gaaattactc cattttctag caaaatcttt
    18961 taagaaattt tttgtcattt catctatttg catttgttgc gctgtctcgt cttctaatga
    19021 accaatttga ctgttacttt cagtactttg aagagttcca cttgtttctt ttactgcttc
    19081 gattgtttct tctgtcgttc tcaattgtgt tttttgtttt tcagaagaaa accaatgaca
    19141 accagtaaga cctatcaaac ataaccaact aaatactaaa attatccctt ttttcacgtt
    19201 tctagtcact gcctttctta tttcacctta cgaaccagac tacgaatttt tgtttgattg
    19261 tacgtgcgtt gataccgagc cataatccgt ccttgctcgg cattctgttc cacactagag
    19321 aaatgttgtc cgccatatga aacatctgtt ataattccgg tgtgaccata gattccagga
    19381 gacaatgcac cacctgcttg ccaattcacc acatctcctg cttgtaaatc acttggtttt
    19441 gggttcatga ttacttgcca accataggtt gtccagttat aatcttcccc tattaacatc
    19501 gcaaacatgt gtccagaacc cattaactgt gggccaccta attgagatac ataccatgcc
    19561 gtaccaccat aacattcccc attatttacg gatcgtccaa tgatccgatc caaaaccttc
    19621 gcattgcctt tactttttcc tgcaataagc gaagtttttt ttgttggtag gctattccaa
    19681 tgcttgatcg caaaagtatc atattccgtt aagttatagg acgttatgat actcattgct
    19741 cctcgataat acggactccc ttcggtaata cctgctgccg catagcctcc acgacctaga
    19801 atcaataaac aacttccagg atctttattg cccacacatt gattaaagtt gctttggctc
    19861 gccaccataa agccataata gtcataacaa gcttttaagt tcggaaactt catatagaaa
    19921 ccaccttcag aaccaccaat tccacgtgca gaaccttgtg ggtagggaca accaggaaac
    19981 caggtaatcc caaaaaagtt cgtatcgttt cttccagatt gtgactgtcc ataagctgat
    20041 tcatagccta attgagaaag aatcacactc ggtaataact gatactttac agctgcacca
    20101 actgctgctt gcgcatgttc atctgtgatt ggaccacgtc ctttaatctc tgaaaaaatc
    20161 ggtaatcctt cggtatattc cccattaaaa gcgacagcta gacctgtagc ttctcctcca
    20221 tgctcagaaa gttctcctga aaaaaagaat ggcaatagaa aaaagggaag aataaagaaa
    20281 agaagacaac ctagacaccc tttcttcatt tcttcctcat cctttcttcg ataatggttt
    20341 ttggactgtt cgtccttttg gtaaagtaaa atcagttcct ggttttgcgt ccaaaatcgg
    20401 cagtgtttta ggatcctttt ctattttttc cgattgctct gttggcttat ctaaagaaga
    20461 aaatgcaggt tgtaacgatt ttggtgcgga aatcgacggt ttactttcag acgaacgttg
    20521 ccccggttgt tgcacagaac gatttcctga tagagtggct accgacgaat taggaacaga
    20581 gtattggttc aataactgct gcattgctgg ataactccca tttttcgcct gatttttcac
    20641 ttggcgaatc tgttgtgaaa gagaaccagc agctgttaat tgtggcacgg gtacttttcc
    20701 agaaggcaac ggaatcgatt gaccaacaaa agcgatacct ttatttaaca atggttttct
    20761 ttgattattc ccttgttgct tactcaattg tgccaatgat tgtacctgtt gttttggtct
    20821 tactgaattc atggacgaat ttggaatcaa accatttgaa agaccagaat tccactctgt
    20881 tttcgatttg gtagaagaca tttcaggctc taccccatga taacgaacat gacgaccact
    20941 ataaggcaag gcttgatttg aacgcccacc tagttcaaag ggattaacca cttgcctccc
    21001 ttttaccgat tcttgtggtg tacgtttttg ttgaaacttt tgaaatccat gtatcgctgc
    21061 agaagcgagt ggattcgttg ctcgatacac attccctgct aatcctgcac ctttgattgc
    21121 caaattttgt ccagcagttg atagttgacc aggcagttgt ttcatttgag acaaagaatg
    21181 acttgctatg tttttcgtgt tgtttatagt ttgatctgca gctcctaacc ctagtttctt
    21241 taataaatct ttccgtttta caatgagtaa aattgatagg agtgctttga caaacatatt
    21301 tcctaaaaaa ccaaaaacag tattcattgg aattaaatcg tctactatgt tatagatcaa
    21361 aaatgccacc aaaataatca cactgtaaaa agatttttga aacatcaagc ccaaaaagga
    21421 ctttaaggta ttcatgagca tataatcaaa tactggaaca aaagaagcga gtaatgaaaa
    21481 aggaatcaca agtaataaac acaacaccaa catttgaaag ataaaacgaa tcatgccaat
    21541 cactacaagt ggtaatccaa tacttagatt aagcaatggc accatagaac caacgactgc
    21601 tttataaaca gctttagttg gttgaatata gacacgataa gccttctttt tccctctatc
    21661 ttctcctgca gcagtggtca cttttgtctc aatatcagat aattcttcac ttgacgcttc
    21721 cttggctaga aattcttgtg gttcaatctc tgcttgatac aattcttcta aatttgttgt
    21781 cccataattt aacaatatat acggatcaac aacagccgct ttataataaa gttggcgcac
    21841 tttttgaatg gcttcctttt gtgtcgttgg cactaaaaca ccattgacat cttttgtcgc
    21901 caattcatct agactatttg tagcagaaaa aataaagcct tctacctcca cggacaaatc
    21961 atttaaccct ttggtaaaag cttctccttt actaggtacg ttactaccat agccaaacca
    22021 aaccattgaa aaaatgacaa cgaagagaaa tcgaataaac accatttttg cgtaatgttt
    22081 ccctctaaat atacgaagag taaatagata taacacatac aagacgacaa tccccgcacc
    22141 aataggatcg tatatttttg aataaatagt atccgaaaaa gtgaaaaact ggtgaattaa
    22201 ctcgttcatt gcagctcctt catagagctt ctcaatgaca aaatcaaggc cttgccaaat
    22261 caatttactt aaactaaaga acatattcgt catcattttt agaaaatctg tgccatttgc
    22321 cccaaataac attttgccta atgaaaattc actatcagat aaataagaag aaaaggtatc
    22381 aatatgaaat ttcccaatct catagatcga ttgatccacc tgcttttctg ccgcatacac
    22441 caatccacca acaaaaagca gtccgaatcc aatcgttaaa aaaaacaaaa cgcaccattt
    22501 cttttcctta tgctttatat aagccattgt ttcacctcat ttctattgca tgattaacgt
    22561 atcctgttct tctacttgag agtgacttgt tttttccgtt gtttgtaatg cagcggtcat
    22621 ttcttcaaac aaactgtgta cattgagttt tcctacacgt ccatagggat ctaacatcca
    22681 acactgtcct ttaatcatgt ggctcatttc agctaagttc gcttcattta cttccaaacg
    22741 taaatgattc aaaatctttt ctcgctcact gtcttcatca aaagcaaaga cgacaccaaa
    22801 attccctttt tctttatctg aacctaagtc accaataaat tgtgtatcta acactaattg
    22861 attcatctgg gaacgcccca cacgtgccat tgctgcaata atactacgtc ctgcgttcga
    22921 attattaaat acccatgctt ctgtaaaata aatcgctgtt ttcttactac tatctcgttt
    22981 tccaaacatt tcacaaaaac gacctaaact aatcatcaaa cacaaagact ttcgatccgc
    23041 atctgtatat agttctggtc ggacattgtc atttggtaat ttcaaatctt ggatctctaa
    23101 aatcgttgtt ttggcattaa agtctaatcc cgggttttct ccataagaaa atcctaaacg
    23161 taaaatcgaa tcttctaccg tcaagcgtaa aaactcacca tattctcgaa cctctttttg
    23221 ttccatttgt tctaaatagt cgaccacatg catcaagcca acttgttgtc cggcttcttt
    23281 ttgaactaaa acttcttgga ttccctttaa taccgcccct tttaaaaggt gattggtacc
    23341 taacggactt aactcatcaa tcatatcctg ggctacttgt ttcgcatcta ctcgggataa
    23401 acaaacaatt ggatctaata caccataatt acggggattt gtagcatcta acgtgacata
    23461 actcattttt tgcaaatgtt ctacaaacaa agggtaatgt ttctgataat acgggtcttg
    23521 aatgagtttc gtaaaccatt tgcgcttttc tcctttggga tccacaaata aactttgtac
    23581 attcataaac gaactataca aaaagagcaa gccaactaaa aaggtcttcc ctttaccggt
    23641 ttttccagtt actgctacat gaggcgcatc aaacaacgca cctttgattc cttccgcaat
    23701 ggctagaaga ttcaaaaaga caaaacgatt tgacgcataa attaattctt ctaatggtgt
    23761 tttttctcct cgagaaccac catcccctaa tgtatcttgc cgaccaatat accagccgga
    23821 ttccatacct aattctgata ctgctgaaaa caaccattcg ccaactgctt ctacagttgt
    23881 tcggtgcttc caatgtaact gccgtcccaa tggttgccct aataaacatt tatagaacaa
    23941 ttctcgttga tcattttttg cacggtggat atggataatc gtatgaagtt gttgaataac
    24001 cgttgcacta ttttgacgaa cttcttcaac cgtttgaccg tatacaataa aacatgcgat
    24061 ccaatcgacg acaggttgcc cattatctac tcgttgcttt aaatgtttta ctaatcctcg
    24121 aacagttaat aagcgttcac taggttcttc atcattttga accaattcct tatgctctgt
    24181 tttgaaccgt tccgatagcc aattcagttt taaaccaata cctccctgtc ctttcaagcg
    24241 tggatagtga attttcattc gcaattctgc tgggaaagaa agatcctgag caaattgaaa
    24301 tagatcacaa tttctcatat tttcaggtgt ttccccaata ggcaacaatg ctaaataact
    24361 actccctaac tcatcttcta attgaagaag gcctttatgt tccttcggta tacgtacata
    24421 cgttccttga ttgtctttca gtacttccca attattttgt tcttctactt tgtgagccat
    24481 tcctcgaata tattgcagac gattgagata caacagctct ttttttacta agggacgaat
    24541 agaaaagcta taaagtaatt gtgtcacttc ttttacataa ggatcacttt cagaaaacaa
    24601 agtttccaaa tcatctactt ctaatccaaa taagcgtgct aaacttcctg ctaaatctaa
    24661 ccagattaga tttattacat catgaaaact ctccaccgtt gctttttctt tgactttgat
    24721 tcctaaaata aatgaaggac gatagacttg accttctcgt tccaacaatg tcactgtttc
    24781 ttttgcataa tacgcaccaa ttgcttgact atcgggagaa aatccctttc ctaatgtgtc
    24841 aaacttcgtc cgtaaattca ttgttcgtgg atacatcacc aactccacat cttcataatc
    24901 tgctaaaagc aacagtaaac gagccatcat ttcttttatt tcctgtgtct tttttggtgt
    24961 gttttttgaa attgttcgtg gaaaaacatg atagtaggcc cagatacaat cctctccatt
    25021 taacaaacaa tttttcttga atgcttttac tggttctttt acaagcacca atgaatttca
    25081 cctcccaata aaaaaggaac aaccagttga ttgtcccttt ttctaatcct ctaaataaac
    25141 atacttattc acaaaaagta attcttccaa tgcattgttt gataccttgt cccagttata
    25201 atacacacaa tcaccattca tcatacgaat catataacaa aaccaatccc ataaataaaa
    25261 atgcactttt tttccatcag gttttagttt tgccagtgct aacacacata aataggggag
    25321 tcctatataa aaaacaactc ctgctggtgg aaaaaaagaa atgacccaac caataaatga
    25381 acgtaaaaat aaatattcaa agattacgac caacaaaaaa gttgctgcat tgactaatgc
    25441 aactggaaat ggaagacgcc aattgcttgt aatctgttgt acgcgataag gttccgcata
    25501 aacaatcgaa taatcataag gttcccaatc cacttcacta tcctcctaat ccataaataa
    25561 tttttcaatg attttaccaa acgcatcaaa tacacgtgtt ggatcattta agaagaaata
    25621 aactgcggca cctgctgcga tagatattaa tgcatttcct acttttgatt tcataaaatt
    25681 tcgcaatccc agataaacaa ccaccattat taaaaaatag ccaccttgcg ttaatataaa
    25741 atctacaatt cccttcagtg tcatttccgt tcttctcctt tcctatccaa ccaattatgt
    25801 gttaattttt caacataata ctgatttgtt tttttcgtaa tgacaatcgt catttgttct
    25861 ttttgtaaaa gtgacgtatc accatctcga aagacgaccg ttgcttttac aataaaaggt
    25921 tttttcgttt ctttataacg caatactttc atctctactt gatcaacttt agctgtttga
    25981 ttgagtcctt caggttcttt catcatgtat gacatatctt ttgcattgtt tttcgcatac
    26041 ttatctaaga aatcttccac aaatccttca acatctttcg cttccgacgc atcaaccgtt
    26101 tcgtataatg tgtcatcata agtaatcatt cgttgttttt ctgtattctt tggtagtgcc
    26161 gtaaaataag gataagcaat aatacgacag cccttgtttg aaatagaaaa gggaagattg
    26221 agtacttgtg tgattgtcac acttgtttct ttcttactct ctggattcat cgagcgaata
    26281 tcataagtta ctttataact agcagttgga atggtttcaa tttcttttaa tccaataaac
    26341 gaagcagcag ttaattttcg aacacctgaa acacttcctg gttcttgaat aaagttttgt
    26401 gcataaaact ctttttttaa tgtttcttga cgttgttgtt cttgttcatg attatcgaat
    26461 gtattcatat acaaagcaac aaaacgattc ataaaggatt caatttcagg tgtgtacgtt
    26521 aattctgacc gactttgtac ttctttcttt tgtaattgtt ggatttcatc tttcaaaaac
    26581 gacacttgaa ccttcgtttt catggattga aaaaatgcca agccccctga aaaacaaaga
    26641 aataaaacca aacaccaaat ccatttcact gctttttttg aatggatttt cttttgcttc
    26701 ggtactttct ctgtataaac tttttctttc cgccgtagtt gtcgtttttt cataagctac
    26761 tccttctagt atgtttttac tagtacgtac gattgacaac gataagcttg tttttctgaa
    26821 aaatagtcca ttcaattacc ctcattttct attccttttc tctttctttt atatccaaca
    26881 aatccagcaa tacttgtcaa cactcctcct agaacagaaa gtgcaacatg tatttcttca
    26941 ccagtctttg gtaagacttt tgtttttcca tctgctgttt tgatttcaat attgccactt
    27001 ggaagtttct ttacaggaat cgacaaatcc tttaccaaat tcccttcact atcttggatt
    27061 aatggaatac catcttttac accaacaatt gtttgatcac ctgctacttt taatggggtg
    27121 gttggtgttg gaatatgggt caattcctct acattactag tgacaatcgg tacactcatt
    27181 ccttgagaag tattcgtcgt aatttcaccg cttggggtta ccgatactgt gacttctttt
    27241 gctggaacaa taggtttatt ttcttttgga attgcttctg atttttcaac aggttgtttc
    27301 ggttcttctt tttgttcttc actggtagac gacatcgttg gctgttccgt acttgacgaa
    27361 tcagtattct tttcagaaga actggttgtt cctgattgtt ccggagttgt gactatactt
    27421 gaatccgttg ttgttgaact atgcacacct tcttcttcga tcgaatcagt cggtaaagtt
    27481 gattcaggaa actctggttc tggtgtcact ggctcttttt caggtttctc tgactgcaat
    27541 tgttcaggtt ctgctggttt ttccgttgtt cctccattta gctctgtctc aacatctggt
    27601 aatccttccc ctggcaatgt ttctacaatt tctgacttag gtgtttctac agtttcatct
    27661 gcataaacca atgaactccc taattgaaac gaaaataatg aaattcctag tgttgttacg
    27721 actgctaatg ttgttttttt catgattatt cctccaattt tttatgcaat tcgtgttttg
    27781 ttcatagacg ccgcactaat attatctgaa cgataaaaga actcccgtcc gttttcttct
    27841 aacccaacat atggattatt tttgaataat tgaatcaata gttcactggt gttgtatttt
    27901 ggatagtttg caaaaaaata atactgtgct tgtcgcccat ccgaaaattc aacaagtaat
    27961 tcataacgat accgcttcaa tccttttcgt tgttttaaag gatctctata ccaacttgtc
    28021 catcgttcca ttcgtggata gagatagaca cgatacacat agaacaatgc cataccacat
    28081 accaccaaaa ataataatcg ccacataaaa attccccctt ttcttctacc tttcttgaat
    28141 catcgaacat tcataccctc tatagagatt tgaaaaatcc atcatcaatt gttcatataa
    28201 acgttgttgc aaatagcgat tgtttcgaat acataattct tcatagccat caatcacttg
    28261 atcttctttt tcatagcatc ttgtagctct atgacgctca gcttgcatga cataaccaaa
    28321 ctctgcacca tatcgttcta ctgttaataa ctgttgacta cgcaataatg caatataaca
    28381 atcacaaaaa tgttcaaccg acatttgatt tttctcacgt ttgtgaaata ggtattcttt
    28441 agaaagcaca ttattcgtta aacaatctga taaatagcga taatctggcg gtcggttatt
    28501 ttcatctgtg aatttttccc ataataaact gatttttatt cgttcagcgg ctagatagtc
    28561 ttgttcgcgt ggataaaatt catcaatcgc acaaagtttt ttatcacctg aataaacaaa
    28621 tccatataat gcgaaacgaa ctcttccttt tcaattggct ctcctaaaaa ttccagtgac
    28681 ataccatctt ctccttccta aaaaaaataa aaaagcagaa accgatttgg cttctacttt
    28741 tctttccttt tatagctctt ttttacggaa gaatccgcaa atgacatttt ttcaaaaaat
    28801 caatcggcac aagttcacga aaacttggag caattttgga tagaatcact tccccatctt
    28861 gtaaaataca atcataaaaa tcatcagtta cttgatactt acgcttctta caataattga
    28921 taaaatagta gcgatcattt tctatttcca ttcgttgttc tactaagcgc atacgaacat
    28981 catcatagaa ataagccaca aatcgccctt caagttcatg tttttcaatg ggatactctt
    29041 ctggtaacaa tctatttttt cgtcgtttat acattgctgg ataccttaga agaagttcat
    29101 ctaaacgtct gtcagtatat ggtaactgac gaatcaacga ttctaatcgt tctttataca
    29161 gatagaataa ttggcgcaag caatagtgta ccgcctctgg attttctaat actgttggat
    29221 cacgtgacca atacgcacca acataaatca taattttttt catttagaca atcacaccag
    29281 caatactaat gaccgatcca caataggtag aacaagtggc atagcgacca atttcctcta
    29341 attctatctc aatctcttct aaagaaagat atgtctgttc ttctgttggc tggcgactca
    29401 tttcccaagt gacagtcacc aatgaaattt cttccataag aggtttttcg ctgctaagtg
    29461 ctgccacaca gttttcatat atcttcattt tatcgcagcc ttttttaacc gctaaaatcg
    29521 caggtattgg caatgaaaat cgataaaagc gaatgaattc tagccttcct ttccttcggc
    29581 taaattccaa ctcttcgagt tcttgttcgt atcccttacg aacttctaat aagcgtgcaa
    29641 tttcttgcca gttctctttt tcctgataac gtccagcttt taccgcttgt tcaatataag
    29701 gaactcgaaa acgaaaataa gacaaatcaa ccatcttttc atttaatgct tcgattgcag
    29761 cctttaaatc caacaggcgc agccattctg ttgtcgtata tgcattcatg caattttccc
    29821 tcctgacgtt cccatccatt ctagatagtt ttgttgctcg tcatttagtt cggcattatc
    29881 aatcccttct tgtacaaagt ctcttcctaa aatacgatct gcttcttgta acaactttaa
    29941 tgtcggagct acttgtttca aaaaccagcg ttctgaacga tctaatgaga atttttctgg
    30001 ctttactgta aaatccaatt cttccatcga acgaaataat tttgcccatc gtttatcaac
    30061 aatccgtgca tcactttcca gtctatccca aacaataagt tttgcattaa ttaaaccaac
    30121 gccaatctct cctaaacgtt tcggtgaatc acctaaaata aatgcttcta ctgcttgtgt
    30181 tgctttctca ttggctaacc gtaactcata tcgattataa ataccatatt tcgttaatgc
    30241 ttctaattct gaaatttttt ctcggttcgc aatttcaaaa cgtttctcat aaaaattaaa
    30301 aaagagagga ctctttcgcg atccaaaata caaagataat ccttcacttc gaaaatagcc
    30361 atcatctaaa aaacaaccgc caatattctg gaatctctta aagtccattt ctaataaacc
    30421 tgctttttgt ttttctagta attcaaagag atcgaaatgt tcttccgttt ccaatcccca
    30481 aagttcatct aacgcaatat cgaatcggct acattgcaca cgtgtataac cagcttccaa
    30541 ctttccttga tttttccaaa tggaatatag ccatgttcgc caatctgttt gttgttcacg
    30601 catgacttcc tcatattccc ggcaaccttg tcctgaaaat tgcacaagta cattttctgt
    30661 tacagttcgt tttgaatgcc agaacaccca gatattccca cgaacagaaa gacagtcaaa
    30721 aagatacaag cccgttggac gtgtttcaaa ttctgtcaga tccattcgta atacacgttg
    30781 aatcactgtt ttgtagtctg tcccaaaaaa ggaaagacgc aaataatcaa tcattgctcg
    30841 aagatctatt ccgcttttca tatacaatcg aaagcgttcc ttgattcgtt gttcaaaatc
    30901 ctctgggatt tttcttttcc cttgttccat ctttctaatg taatcttttg agcagcccat
    30961 caattgcgca aatcttgctt gtgatagcgg ctttttatct ccacttatat tatgaattgc
    31021 acttaacttc tttctgtagc tttttagctc aatcggtgtc attttctcgc tccttttata
    31081 aaataacaaa atcgattttt tttaaccctt tagaaacacc gatatatcaa ctagtccccc
    31141 tcgttttttg ggaaaagtag tacaactgct gaccttagat aatcacttga tacaaaaggg
    31201 tttataaaac ttttttctat gtgttatgtt atttctgccc cccatattat atatcggggg
    31261 gctttacaca aagaggccgt gcgcaagcgc acgacctctt tgtgagctgc acacgctgct
    31321 agcgagtgcg cattataggc ccatgcttcg cagccttaat gcgcaccgcc aggcagagtg
    31381 cggctaccag actacgtcta gagccctccc gatagataat aactacaaaa ttaaatgatc
    31441 taattttgtt atttcactat atttttcagg agaaaaaacg cgataaattg acaaagttaa
    31501 atcctcttct aaatctactc gataatgata caatcgagtc aatcgttcta tatctttttt
    31561 cgttagcaat acttgattaa taacttttcc tgtaaaaaca cgttctttgc gcaaaaagcg
    31621 gtaatcagtt acttgttcaa tacgattcaa ccaatcataa aacgttctgg aagaaagaga
    31681 aggattaatc attcgtattg ctgtagctac tctataataa caactctctg ccatttaact
    31741 tcacctcctt agttgattac aaaatatgcg catcagaaaa acttgttcct tttggatctt
    31801 ttgctaaata catttggcgc tctagttgtt cttgtaacaa ctgattatca tctcccatcg
    31861 tttgatcttg actatcctct tttactgtaa aatcatagac aatcatttca gtaaatttct
    31921 caaattcttt gataaagtga taatctttgt aaacaaatgg cgcaaaaaac tctacaggta
    31981 catcaaatcc tggaaaagca tatccacgac caggttgatc tttgttgtaa aatggcttat
    32041 ttttaaaatc ttctccaaaa gtcattaaat aaccaatggg agacaatcga ccaacagaaa
    32101 tacggaatgt taaattatcc cgaacaccac ttggaaaata ttctgcatct ggtcgttgca
    32161 ttgctaaaat aatgtacatc cctgcttgac gaccctttaa tactaatggc tgaatcaatt
    32221 tatcgactct atttctcgct tccatatcca acgaaccata aaaagctgcc cattcatcaa
    32281 aaaagataaa atgcggtggt aacccataat aagcataatt tttccctggt tcatatttag
    32341 gatctttcat ggttttcata taggcatacc gttgattcat ttcttttaat gcatttcgta
    32401 aacaaataat catttcttca tttattttgt aaaacacatg tcctttgaat acatcgacgt
    32461 cacctaatgc tgctaaatct gccgcttttc catcgcaaat atctactgtc ccaacactta
    32521 aacaagcttg aattaaagaa tacaataaat aggttttccc accaccgatt gcaccagcaa
    32581 tcaacatatt tggtgattga tcatataccc aatccaaagt tttcattaaa tgaatacgtc
    32641 cattttctgc tatacattga tcaataggaa tccgaccaga atctgaaagg aatacataat
    32701 tgattcgggc tttttctcgt tcttcacgaa ttaaatcacg caaaaatact tcagataaca
    32761 aatgacccat ttttaaaaat cgttcgtgaa aacgcccacc atctaaagga aaagaaacca
    32821 ctaattcttg tttcttttga taaaaataaa cttttggtaa tctcattttt tcccttgttt
    32881 gtttctcact aacttgtttc tttgtataaa caaaccgatt gtcaattaac attcgaacaa
    32941 gtaactgacg ccaataaaca gaggcaaaat atccttcttt tagtcgcgac caatgcatca
    33001 accctaaaat taacccacta accagcaaca aatacaacac aatacttatt ccaggaataa
    33061 gatacatttg ccaattcgaa aacgtactta aacgtggata aaatactttc caactaaacc
    33121 aacctaacag aatcaaaaat ggaaacaaaa agaaaccata atagcaaaac cataaataac
    33181 gattgaaata gcgaattcgc cgaccacgat acttgaaaaa atgagctttc aattgtcaca
    33241 ttcctccttt ctgtttttac ttttcctgtg ctaaaaactt ttgacaaaaa gcaactaata
    33301 caggaatatc acatttagta aaaaaacata atcgaaaaag atttaatcga tttttataag
    33361 ggtgtgcaca catattacat attcgtacta tacgaatcca aatcacttcc tgatgatctt
    33421 gtttccactg gtacggtaat gaaaaacgaa caagatcacg taaaaacata cactgcccaa
    33481 taaccgcaca aatatatgca tttgtttgta caaaaatcgt tggattgtct ccaaaatact
    33541 caatcaattg ttggatattt tgataacaag cacaatctct caaagtattt gattggtttt
    33601 atctgaattc aaaatctccc cttccttcta tcttagataa aaagaatagg aagactcctt
    33661 cctattcttt caaaaaaacc ttattttttc tctttttcct tagaatcaac acttggttgt
    33721 ttttgatcta aacctttttc ttgtgattgt ttcatattag gattatttgt tggagcttct
    33781 actttctcta atcctttcgc ataaatcact aaatctgaat attcacgatt gccatcttgt
    33841 gctggaatat ataccacatg atattctgga tcaattaatt tcacaggatc acgtcgttta
    33901 aaaccagtca aatctacatc tgctggaaat ttaactcgtc gtgcaatctt tggttcatct
    33961 ggatttccaa aaactaattg tgctcgctgt gatcgaattt ctcccgtata atcgcctgtt
    34021 tcattatcaa atacacgatc agactcttct aatgcgccaa agcgtacggc tcctaaacaa
    34081 gtttcatcta atgcttctgt aatgtcataa ttatttggaa attttaatcc catcttacaa
    34141 aacctcccca atttttacac cagttaaaaa gacaccaaca tcttgatagc cagttgttcg
    34201 acgctctgtt tgtcccatat catttgtttc acgactattc actcgttctt tacgaaaaac
    34261 aaaataagct tcttcaaatg aaatacgcac ctctttttct ggtaatcgta atcttttatc
    34321 ctcttcagct gtgagataaa caaaaaaagc aggctgttct tctcgcgaac actctgcttg
    34381 taattgaaca tatcgcccag acacaccatt aatttccttt ggtggattag gttcccgtga
    34441 acccaataaa aatacttgac ctaaaaactc tttcttcata cgcaatgctt tttctgccat
    34501 aaagtttttc ctcctcttaa aaaccaaaat aaattctaaa tatttctaca ttacaatcaa
    34561 acaagcggtt aaaaatccta accgcttgtt cctcatgact aatctttggc tttacgtact
    34621 ttataaagtg ttatacctaa agcaatgact aatactacta atccaagaac cataagtata
    34681 ctacttgttt gttcacctgt ttttggcaac attggtacaa cagtagctgg tttaacccgt
    34741 tgttctggtt tcactggttg cggtggtttt ggcgcttcca caatttgaac cgtttgatct
    34801 ttgtttgtta gatctacatt gtgtttcgcc acttcttcaa acgtttcttt ctcatcttcc
    34861 gttttcgctt ggagccattc cgcaaaactc aagccttttc ctgcaagatt gcgaccgtcc
    34921 actaagaatt caaataagaa ttccatcatt tctttatcgg ccgcaaagac tttttccgca
    34981 tgagtgcctt caaatggtgt gccgtctggt gttaagtagc cttgaacaat taagcgatag
    35041 atttgaccaa tcgcaagacc gtctactttg acccattcaa gcacagtttg atttggcaag
    35101 gccaagatct cttttccgcc atttttattc gtcgctttcg tcgtaatggt tggattactg
    35161 attttgatgg tttggtcatt gtcggtaata tctgcgtgag aagccaataa tacgccttct
    35221 ctaaacagat cttcaaagac cacgacttct ttgcctcgca acgcacgtgc gtctagaata
    35281 aagtctagat tgactgtacc atccgttgtt tctgccacaa acgttaaggt acttgtgact
    35341 tcttttccat ctactagcac tggtttttcc gttactttgt ccattagaac accgttgact
    35401 gtgtatgttt ttccaacgac caaatcgtgg tatttcacag cgtctgtaat ggtgactttc
    35461 gttaatggat taacctcttt caagccagtg ggtttatgtg tagccgttgt acgtacactt
    35521 gggttagtta ctcgtaccgt ttgccctttg tcgttgatgt ctttatggtt tgctagttct
    35581 tcatcatttc taaaaagact ttcaaacacg acgatttcac gaccatttat acctgtcaaa
    35641 tcaaaggtaa atggtacgat caccgtttca ttttctgctt tggcaataaa gccaacactc
    35701 gtttctaccg tatttccatg cacaagcaag ggttcaccgg ttgctttatc cattaagatc
    35761 cctttgacca agtatgcttt tcctggaaga atctcggtaa tttcaacggt atcgtttaag
    35821 gtaaacaatc ctgttgggtc tgcgactgtc aatccgtctt caaagacagc cgtggtatga
    35881 acggttggat tattcacttt cacactttgg gcttcatcgt tgatatccgc atgtgctgca
    35941 acttcaatgc catcacggaa aagtttttca aaaacaacga tcgtttgacc tttcagaaca
    36001 ctagcattaa ccacaaattc aaggtctttt gtgccattga ctttgtctgc aataaaggcc
    36061 aaggtacttg tgatttcttt gccatcttgt aaaattggcg cattcgttgc cttgttcatc
    36121 aatactcctg aaatggtgta ttcttttccg acaaacaagt tggtataaga aacactgtct
    36181 ttaatgacga tcgtttctaa tggatcaacc actttttcac catcggcttt atttgacgct
    36241 tgtgtttcta gttttggtgg aatcaagtaa ttacgtacag aaaccactaa cgtttcccca
    36301 tcatctggcg cattttgttt gaatgcaacc gtgaatgctt gtttatctgt atttggttgg
    36361 aaactttcta atggggcatt ttccaagaag taatagtcat cggcaactag acctttcact
    36421 aaaatttccc cgttttgatc agtggtatat tcaccaattg cttgattttt accgttatac
    36481 aaggtaaagt tcacacctgc gagcggcgtt ttcttcttgt tccattcttc atacttgaat
    36541 aattttacac ttttccgtgc ttgacggttc gcaaaatgga tcactttgat cggttctgta
    36601 tcattggtaa tcgagaacac taatgggttt tgattcaaaa cgtaatttac gggggctttg
    36661 atttcttcca aacgatagcg atcttttcca taagtaagtg taccgttagt taggaaaaag
    36721 cctttttcat tggttttaaa gatatccgtt gtttctgtat catttggaat ctccattgtg
    36781 acataacgat tggctaaagt atcaaaaatc ttgaattctg tattagcaag tggaatcact
    36841 tttcctgttt cttgatccac tttcaccact ttaagacgtt gttcaattac tttatcttct
    36901 aaaacataat ggaaagtttg cccattttca gaaattgtga cttcaagtgg ttcaaatagt
    36961 ttataccctt cttttccttt ggtttcagaa agaatgtacg tatcaaagac aacggtattt
    37021 ttaccaaaag tagcataacc atcattgtct gtcacaacgg ttttcaccac tttgccagtt
    37081 gtttttgacg tcaaagtgat ttcaatgcca gctaattttg gtttgttatc tggattcgtt
    37141 gaatcgacta aatctttatt agcaactttc actaaatcaa tggttccttt gatcacttga
    37201 tcttttgcgg tcgcattgac agtttttcca ggttcaacaa caatttcaat tgcttcatca
    37261 gaaagcacat aaccttttgg cgctttgatt tcttttaaaa catatttgcc aggatcaaga
    37321 tctttaattt ctgcctgtac tttgccgtta atttttttca aggtaatttc tttaatcttt
    37381 ttcccatctg cttgatacaa accatagacc gcattttcta aagaagctgc accttgtgct
    37441 ttcacaccag tttccgcatc ttctttaaac acacgaatgt ttccttgttt tagaatttgt
    37501 aaattaataa cagacgcatt aggttctgtt ggatgtaaca caccaattgt ttgagctcct
    37561 ggacgacgat aggctaatgg cgcaccttga actttaattt tattcaattg aatttttgct
    37621 ttatccggtg cctcttttgt gactgtaatc catacttcat tgccgtgaat agatacattg
    37681 acaccttttg gtttttgaat gtctttcaca tatttcaaaa aatcattttt attctttact
    37741 ttcaacgttt cgccaatttt taccgtatgt gtttgattat taaaagttgc tttttcacca
    37801 aagttattaa tcaaacgttg aatttctgct tttcgacgat cataatcaac acggatattt
    37861 ttgattggga tttttgtgcc caaagcttcc caaatcataa attgtgccgc aatgtattgt
    37921 tcatcggatt tgtctttatt tgtgacatat cctaaataag agatcaagct tgtttttttc
    37981 cgtacatttg aatttttcaa atagtttttc aaagcagtag ctgtataaac ttgaccttct
    38041 gcggctgaga caccaggctc aatacaaaac gccacttgtc cattaatctc aaaacgaacc
    38101 atataattta aagtgaagtt tagattgttc ggactagaag taacaccaat attttcgccc
    38161 caatcaattt tccgaccacc taaaacagct gcattggttg cacggcgaac acgaaccgaa
    38221 cgattggttg gtactgttac taacagtgta ggtgtacctg tttttggaat gttctgctct
    38281 tttttctttt gattttcaat actagccgta gattctttgt ttggtttcgt tggttgattt
    38341 tgactagctg cggttgaaga gattgttttt tcaacgtttt cctcattttt tccttctttg
    38401 tcagcagtag ccgctggttg ttccactgtt tcttctattc gtttcttttc ttccgcttgt
    38461 ttctcagaag actctggctg cacagaaggc gttgcttcgg cagctttttc tccttctaga
    38521 gtggacgttt ctgaagcagg ggttgtaatt gaggcagttt cttcaactgg ttgtgaagta
    38581 ccaggactat tccctgggtg ttgtgtttcc ccaatcgtct gatcgagagt cgttttggaa
    38641 ttgaccgttg gcgcttctgt cacaggggcc tgttcaacag tggcttcacc agctgggacc
    38701 ccggcttctg ctggttggac ttctgtcact tcagaagcga cttgggcaat ggcttccatc
    38761 gtaggttgta tagccgtcgt ttcttctgca tgtgcttgag cagttcccac caagaaacag
    38821 aattgagaaa aagccaccaa tgcgagtgct ttcaaccaat tcattttcgt ttttgcatac
    38881 acaagaattc ctccttttcc tgagaatttt atataataaa acaaaacgcc gttaccaaaa
    38941 gtgataacga cgtgaactgt ctcttctatt tttatctggc gctcttatct gaacacattt
    39001 catcaatgat tttaccctcc cactataatt acagaacaaa aaaagaacct gcttcgtgga
    39061 aatcaactgt ccatttccca attggaatac cagctttttt ggcaacttca ccatcaccaa
    39121 atctcatgcc ataccaatta ctaccttcat ccttaatttc tttccaacca tatgacatag
    39181 cttcatctaa tgaatcaaaa atcatgacac tattgccaat tgttacagga tctggcttaa
    39241 gatcttctgg aagagaaata tcaatcatac cataatgatc cgattcctca gtattattgt
    39301 cattactagc tactggtttg gttgttctac tggcttattt tgatacaaca agtactctta
    39361 ttcttctttt acttctccgt tttcaatttc ccattcaaac cactccgcaa agtcttgctt
    39421 aaaaccatct actcgatacc tattttgtaa ataggcatct tctgacgtcg taggatctaa
    39481 ataggtaggt ttattctctg gacgagcata gacacctacc catgtttcgt aatctccttc
    39541 aaaataacta tctaccaaat agcctttttt tctaagaatc tcccgaactt gatttttaat
    39601 tattgatact tgttcaaaac catcactcat tctatcacct caaataactc tagattctca
    39661 taaatattcc cgacaatttc aatcctatca atgatctcta acaaatcgct acttatgctt
    39721 ccccattcgt ataagaattt cccttccgca aaataaattt tccataaact tcttcatgat
    39781 cgtcccaacc aatatcactc tcgaaaaatt ccacgttgtt cttatctttt agctcagtaa
    39841 atgccataag ttcaacatgt tttccaacct cgaaacaatc acaccaccca tcaaccgtta
    39901 cacgtgtgcc ttcaatacct aagaaacttt gtcctcgtgt attaaacact aaaactttcc
    39961 gcattttttg ctcattaatt aatcacgcgc gaaatctagg aatcacaact tattcgcttc
    40021 ttctttataa ataaaaaaac tccaataatc ggaaattact atcttttcct cattcctttt
    40081 ttaaatcttc atacttcttc ttatctttgt cctaacctaa taacacaaat tttgaagaaa
    40141 aactcagtaa aacctgattc tttttttatc ttcacaacaa ccaacttttt cttcagatcc
    40201 ttttactaga acttgtatac aaaaattgtt gaatgctgat ataatttgcg gctacttgaa
    40261 aaaacgatag atgtaaaaag ataaatagaa tcatttttta ttctatatca gtctatgatt
    40321 cattgcttat caatcaccca acccattcga tgccgttttt tttagagaaa tttaaaaaag
    40381 accgtacgaa tctcgcatta tccgattact tttccagaaa agatccccaa ttctgtataa
    40441 ataaccctat cttcttgttg gtttcatttt ctcatataag aattcagtca atctacccac
    40501 tatgaccatt actacgtcca acacaactga catattaacc acgtaagtat tccctcacag
    40561 atctccgaat ctccatggta tggattccca tcctgacgct gcagaggaca acatatttca
    40621 tgtggctctg tacccttttg atttggaaac actacaaatc aatactcatc tataacttat
    40681 caagcgaact ttcgctaggc ttctagtgat tactaaattg ttggataaca tacatagccc
    40741 attttatcta gctgttattc ataacagtta gttcttgtat tacttcttcc gcttgtgttg
    40801 ccattgagct tgtcaaaaag ttacttagaa aaaagctgcc agtaaagcaa ctttcaacaa
    40861 accctttttg tttcttatca tatcaagaaa cctcctttta taaatttttt ctataataaa
    40921 aaacgtcgat aacttaataa gtatcgacgt aaactatttt tatatcccgt aaatcaaaaa
    40981 ttctaaagaa agatttccta tataagcata ttggataatt cgattagtat tgggtatatc
    41041 tctaccattc tcatacctat ctatggacca ttttgaaatt gaaggagaaa aaagctttcc
    41101 aaactcctcc ctttctagat aataatcttt cctaattttc ctcatcctta atcccatact
    41161 aaaagaattt atctttttaa aatcgctaac tctttcatct tttggaagta tattcttata
    41221 atcttctccg tacataaggt aaggaacagt gaccttacca agataggcaa tattcattag
    41281 tttttcaata tctggaatat taataccttt ttcccatcta cttataacat ttttgcctgt
    41341 atagatggta aagtttttac caaatttttc aagcgtctct tcccggttct ttcggacttc
    41401 tcgtattctt tttcccataa caattttatc gtcttttgat aaactaaata tctcactatc
    41461 acgattaatc tccttcaaaa tttctttttc attacttaat agaaaaatat cgattttttt
    41521 ttgcatttct tttgacggat ttctctttct atttaacaca taactgagta atacttcact
    41581 aattcctata ttatcagcta actctttgtt aagtaactta ttcatatctc tgtatgcaat
    41641 tagtttaccg atgagaatct caatcttatc ttcctcatct tttattagag tttctatatt
    41701 cagaatcttg cttagagtat tatctacgtc tttagggatt tttcttgacc ctttttcata
    41761 tttaactaaa gtactttgtg aaatacctgc taaatcagct aacttttttt gagatagttt
    41821 tttctctttt cttagagatt taagaaccct tccacttgaa ttatcaacca tgaaaaaagc
    41881 acctcctatg agatgctttc atcatatact gacagctaaa aatcttcaag aaaaatattc
    41941 caattttgtt aattttagta tcgccgtgat aaccaaatga cagtttaaaa tcttttatac
    42001 agataatcct cagtgttgca tctactcaaa aaggtttatt taataggttt ttcgattgat
    42061 tataagttat ttcacactat cttgctcatc cattttcaga acggccatga aggcttcttg
    42121 cggaacttcg acggagccga tttgtttcat ccgcttcttc ccttcttttt gtttctctaa
    42181 gagtttacgt ttacgagaaa catctccacc ataacattta gccaagacgt ttttacgcaa
    42241 ggctttgatg tctgaacggg caacgatttt ttgtccaata gctgcttgga ttggcacctc
    42301 aaattgttgg cgtgggatta gttttttcag tttttcaacg attgcttttc cacgttcata
    42361 ggcaaagtct cggtgaacga taaagcttaa tgcatcgact ttttctccat tcagcaagat
    42421 gtccatcttc actaacttgc ttttttgata accagacatt tcataatcca atgaggcata
    42481 gcctttcgtg cttgatttca atttgtcgaa aaagtcaaag acaatttcag aaagcggaat
    42541 attatagacg acatttactc ggtaatcatc taaataatcc atcgtaatga attctccccg
    42601 ttttcgttga gaaagttcca ttactgcacc gacaaaatca tttgggacca tgatctgtgc
    42661 tttgacgaat ggttcttcta catcctgaat cgttacaggt tcaggaaaat ctgccgggtt
    42721 atctactgta gcagtcgtac catccgtttt attaacatgg taaataacgg atggtgcagt
    42781 cgtgatcaat tctagattga attcccgttc caagcgttct tggacgacat ccatatgaag
    42841 aagtccgagg aatccacagc ggaacccaaa acctaatgct tgagaggttt ctggttcgaa
    42901 ttgtaaagca gcatcattca attgcagttt ttctaaagct tcccgcaaat cgttgtaacg
    42961 agaagtatca attggataaa gaccacaata aaccatcgga ttcatttttc ggtaacctgg
    43021 taaagcttca gcggcaggat tgtctgctaa cgttactgta tcccctactc gtgtatcttg
    43081 gacagttttg atacttgctg tgatataacc gacatcaccg accatcaaaa agtctctagc
    43141 aactgctttt ggcgagaaga ccccgacctc tgtaacatca aatgttttgc cattactcat
    43201 cagtttgatt ttgtctccgg gtttgaccat accgtccgtg atccggacat ttagaacaac
    43261 accgcggtaa ctatcataaa tagagtcaaa gatcaaagct tttagcggtg catctaagtc
    43321 tccacttggt gcaggaacat attccacgat ctgctcgaga atatcttcaa tcccaatccc
    43381 tgatttggca ctggctaata cagcttcact agcatcgatt ccgattacgt cttcgatttc
    43441 ttgacggaca cgttcgggat ctgctgcggg taggtcgatt ttattgatga ctggcaggat
    43501 ctccaaatca ttgtctaacg ctaaataaac attggccaat gtttgtgctt cgattccttg
    43561 tgctgcatcg accactaaaa cggcaccctc acaggcagca aggcttcgag agacttcata
    43621 ggtgaagtcg acgtgccctg gggtgtcaat caagtgaaag atatatgttt ctccattttt
    43681 cgctgtgtaa ttgagttcta cagcatttaa tttaatcgtg attccacgtt cacgttccaa
    43741 atccatcgag tctaacagct gatcttgcat ttcgcgagac gtcacagtgt gcgtcatttc
    43801 taaaatacga tcggccaatg tagatttccc atggtcgata tgagcgatga tcgaaaaatt
    43861 acgaatctgc tcttggcgtt ctttcatttt ctttatatcc atagcgtctc ctcttttcat
    43921 ataatcagca ctttccatta taccaacgaa aagcagtaat ttaaagagtt tttaattagt
    43981 cagctataga agtttttttt gtagaatttt gctatactgt tatcaagcta ataaatggag
    44041 atgaaaaaat ggatcaaaaa gattttagag aaaatcttga attaaaaccg gtcactcaag
    44101 aacatatcga tcaattcaat gaattgcttt cctatgtgtt ccaagtgact gaagcagaca
    44161 tcgaggaaag cgggtttgag aataaacgag cttttatccg ttccaaaaaa ccgattttgg
    44221 aagtatcgaa agtgttcgga tggttccacg aaaataaact gatctctcaa atcgctatct
    44281 atccttgtga agtcaatatt cacggtgcac gttataaaat gggtggtgtg actggagttg
    44341 gaacttatcc agaatatgct aaccatggat tgatgcaaga tctaattatc gttgcattgg
    44401 ataatatgcg caagaataag caatggatct cttatttgta tccttacagt atcccctact
    44461 atcggcgtaa aggatgggaa atcatgtctg ataaactttc ctttaaaatc agagatacac
    44521 agctacctaa acaaatccca gtaagtggta tggttgagcg attaccagtt gatcatccag
    44581 acgtattttc cgtttatgac aaatttgccc aacaaaacca tggtgcttta ttccgcagtg
    44641 attttcattg ggaagagtat tggcgtttcg aaaatgaaga tgagcgcaca gccgctgtct
    44701 actacgatag caaccatgaa ccaagaggtg ttctgttcta ctgggtagct gaagaaatat
    44761 ttcacgtaaa agaaatgttc tatcttgatc aagaagctcg aaatggctta tggaacttta
    44821 tttccgcaca tttttccatg atctactggg tacatggaga tatttataaa aatgagcctt
    44881 tagcattttt gattgaagat agtcagatca aagagcagat cgaaccatat tttatggctc
    44941 ggatcgttga tgtaaaagaa ttccttcaac ggtttccgtt tgttggaaca gctgatgctt
    45001 ttcatttcat cattgaagat cctgtcgctc cttggaataa tggtgtcttc gctttaacat
    45061 gggatgaaca gggacaagtc cgtgtcttaa atgaacctat aggaaaatcc gttcgactgg
    45121 atatccaaac attgacttgc ttgatgatga attatcgccg tgcttcttat ttggcaagaa
    45181 tcgaacggtt agaaacagat gaagaaacac tgaagtcact agagcgtatc attccaaaca
    45241 tggaagctta ctttagcgat tatttttgat aaaaaggatg atgtttagat gaaaatttat
    45301 tttgccgcac caatgtttgc taaaagtgat ttgttatata accaacagtt agttaaagaa
    45361 atcagagagc tctcttctga gctttcgatc tatcttcctc aagaaaatga agcaatcaat
    45421 gacaaaactg cttatgcaga cagtcgaatg attgctcttg ctgacacaga aaaagtgttg
    45481 gctagtgatt taatgattgc tttactagat gggctgacga tcgatgccgg ggtagcatcg
    45541 gaaatcggtg tggcttatgc gaaaggcatc ccagtgatcg gcttatatac tgatactcga
    45601 cagcaaggcg gaacccaccc gaaaaaaatc gctgcactac aagaaacagc tgaaaatcaa
    45661 tttcactacc tgaacttata tacaataggt ttgatcaaat tgaacggaaa agtggtttct
    45721 tcagaaattg agttgctttc agaagtaaaa agatttttag atggagggac tttcagtgat
    45781 taaagaaatc aaaaaggtgc aaatagcttt acttgctttt ggtgtattcg ttgtctgcta
    45841 taatttttat gaatttatca cacaaaaata ttcgacttct caaggaatca catttatcgt
    45901 ggaatcttta ttagggattg cattgatttt catgccacaa gtcattttga aagttttcaa
    45961 acttaaaata ccagcagcaa tcgttttgtt ttactggttt ttcttgttca tctctgtctt
    46021 tttaggcaca gggatgcatt tgatcagtat catctctttt tgggacaaaa tcttacatgc
    46081 ggtgagtcca atggtcctga cagctcttgg ctatggattg attggttact tgatgaaaga
    46141 tgctgagata tcaaaaacca gtccttggtt gttcctctta ttcggctttg cgtttgctgg
    46201 actttgcggc gtgttttggg agttctggga attcttatgc gaccagttct taggcatgaa
    46261 tcttcaacgt tttgctgctt ctgatggcac actgtttgtc ggacgagcag cattgatgga
    46321 tacgatgggc gacttgctga caaatacgat aggtgctgcc ttaatgggat tgtttgcatg
    46381 gtctcaaagt aaaaaagatg agcgttactt tgaaagttat aaattagaaa aagtgaaaaa
    46441 tacctaataa aagaggttgt gacagaagcg ggcagcttca agaaatttcg gcttattttt
    46501 cgaagaaact acttctggaa cactgtttat ttgaaaaaag gaggtctgac actagttgtg
    46561 tcagacccct tttttctttt atagtctcaa tggaagatta gacgatttct tctagctctt
    46621 ctgttttgaa atgaagttgt ccatcaagta aagtaatcgt tacttttgat ttaggcataa
    46681 catgtcctgc aacgatttct ttagctagtg gtgtttctac ttccttagtg ataaatcgtt
    46741 tcaatggtct tgcaccatat gctggttcat aagcattttc agcaatccac gttttggctt
    46801 catcactgat tgtcagcagg atttcttgat gttccagacg ttgtgccaat tgcgccacca
    46861 ttttgtcaac gattcctttc acgttgtcta ggctcaatgg tgtaaataaa atcgtgtcgt
    46921 cgattcggtt caagaattct ggtttgaagt ttccacgtaa tagcgtgttg acttgttcag
    46981 ccactgcttc tggaatcgtt ccatcagcag tcacgccttc cagcagtaac tgtgaaccga
    47041 tattgctggt catgatcaga accgtatttt tgaaatctac tactcgccct tttgaatcag
    47101 tcaagcgtcc gtcatctagg acttgtaaca agatattgaa gacatcggga tgcgcttttt
    47161 cgatttcatc caacaagacg attgtataag gatttcgtct gacagcttcc gttaattgac
    47221 caccttcttc gtaacctaca tagcctggag gagctccgac tagacgagac acagcatgtt
    47281 tttccatata ttcactcata tcgatccgta ccatatgatc ttctgagtca aacaagttct
    47341 cagctaacgc tttcgctaat tcggtttttc cgacaccagt tggtcctagg aaaaggaaag
    47401 aacctagagg acgatttggg tcttgcaatc cagcccgtga acgaattacc gcgtcactga
    47461 ccgcatcaac tgcttcatct tgaccaatca ctcgtttatg aagtgtttca ttcaatttaa
    47521 ttagtttttc tcgttcacct tctacaagtt tcgttacggg gatacccgtt aatctgccaa
    47581 cgacttgagc aatctcattt tcggtaacgg actcttgaac catcttaatc tcgctgtctt
    47641 ttgctttagc ttctaattcc ttcaattctt tttctaattg aggtatcgta ccatgacgca
    47701 atacagcagc gcgttctaaa tcatagttat tttctgcatc ttctaattcg tgttttgctt
    47761 tatcgatttc agcacgtttt gctgaaacag aattgacttc ttctttttct gtttcccact
    47821 gcatcttcat cgcatttgct tcttcacgaa gttcagctaa ttcttcttgc aaatttttca
    47881 agcgtttttt acttgcatca tctgattctt ttttcagtgc agcttcttcg atttccaact
    47941 gcatcaaacg tctagtaact tgatctaatt ccgttggcat agagttcatt tctacccgaa
    48001 tcgttgcact ggcttcatcg atcaaatcga ttgctttgtc cggtaagaac cgatcagtaa
    48061 tataacggtc agataaagta gctgctgcta ctaatgcgtt gtcatggatg ttaacaccat
    48121 ggtggatctc aaaacgttct tttaatccac gcagaatact gatcgtatct tccactgttg
    48181 gttctttgac taataccttt tgaaagcgac gttccaacgc tttgtctttt tccatatatt
    48241 gacggtactc atctaaagtt gtggcaccga tcaaatgtaa ttcaccgcga gcaagcattg
    48301 gtttcaacag atttccggca tccatacttc cttctgtttt tcctgcccct acgatattgt
    48361 ggatttcatc gatgaacaag aggatacgtc catcactttt tttgacttct ttcaagactg
    48421 cttttagtct ttcttcaaat tcaccacgga attttgctcc agcgatcaat gcacccatat
    48481 ctaatgaaaa aatcgtttta tcttttaaat tttcaggcac atctttgcgt acgatacgtt
    48541 gagcaagccc ttcaacgatt gccgttttcc ctacaccggg ttctcctatc agaacaggat
    48601 tattttttgt ttttcgtgaa agaatacgga tgacatcacg gatttcttca tcacgaccga
    48661 tgattggatc catttttccg cttttgactt gctgtactaa atcaacgccg tatttttcta
    48721 atgctttgta ttgttcttct tggttttgtg aggtcactct ttctcctcct ctcatctctt
    48781 cgatgttttt acgcaattct ttttcagata atccgttttt attcaaataa acagttaacg
    48841 gataattttt taatttcatc aacgctaaaa taacgacttc cgttgaaaga aactcgtcgc
    48901 cgaagctttc acgtatttgg tctgcttcat tcaataatcg aaagaaattc tggctgaggt
    48961 tttgtccata ttggacgttt ccaccagaaa caactggata ctcatccagt agacgatcaa
    49021 tttcatgttc aaaagattcg acatccaatc cggcatccgt atagaaattt cgaccaaaat
    49081 gattagattg taaaaagatt ttccatacat gggcaatgtc gatatcttga tgttttcgag
    49141 tgaccgcaat ctgttgagct tcagcaatcg cttcttgaag cgtcgtagtc attttctcaa
    49201 tattcataca ggtataccct cctaattaaa ggtaagatca cttatttctt tgatctttac
    49261 aaaaactatt atatcgcttt ggtcaatttt ggtcaaaata tacacatagt tttttgactt
    49321 tttttctcga cttatataaa tcttaaaaaa acaaaattga ttgtatgtat ataaaaaaag
    49381 agccaaacaa acgtaaaatt atcttatcca taacgttttt ctttgatttg ataaaaaggg
    49441 tagatcttat aaaagaccta cccttgattt tctttattct ctttttttac ttctattatt
    49501 tcttctttga tcactcttcg ccgttcagca atcacataca caaatccata gagaaatggc
    49561 aagataaagg aactgaaacg atacagtaaa agcgaagaaa ctgcgtcaac tgttccaaca
    49621 actggtctga ataataacaa atagacaaat tcaaaggaac caataccagc aggcgtagga
    49681 ataacccctg aaagcactac tgcaaagctg ataaacgaaa tggtcagtag aaaatctatt
    49741 ttaggatggt tttcaatcag aatcaaataa ggaagtacat accaaaatac aagttttaac
    49801 atattccata gataaatccg caatagcgca gtcctgtctt ggataatggt ttggaccgtt
    49861 tcccttaaag agtagatctg ctgattgcat gtatccaccc atttccgcaa acgctcactt
    49921 ttaaataact tattcgataa gctgacaaaa aatatttgaa cattcaagct gacggacatc
    49981 gccaataaaa aggcaacaat cacgatcgtc aaaaggatac cagcgatgat aaaccagatc
    50041 attgatggac cattagaata aaaaagagag aattggatga ccaagccagc taatgcataa
    50101 gtgatcactg ccagtttgta cataatcata tggagtgctg tcacccctgc tccctgggat
    50161 agcttcattc cttttttgtt ataaaaataa atctccgaga tcagcgttcc tgtaccaaac
    50221 gaaacgattc ggtaaaacgc aatatagcta gaggtcaaga acccatcttt cgttgtaaaa
    50281 ttcggcgcga aaggttcagc aatttctttg attgagcgcc cttcagcgat ttggtaaact
    50341 gtccctaata taacagccgc tgccaaaaca acaacactgg tagacagcaa ttcggcaaag
    50401 atatctgcaa atgattgatt gattaaataa taaataatgg caaaaatcac aatcagcaaa
    50461 agcagattca gaatgatttt agttttcgtt cctttagacg acatctcctg ctccttaatg
    50521 gaaaaaataa atgagaatca aatcaacaag tacacctgca gcgaatccta tagtaaactt
    50581 ctttttccga gttttatgat ggaaaacttt tcgagagatc aatcctccca aaccaccgcc
    50641 taacaggctg acaaatatca aattattctc aggaacacgc cagccgctag ttctagcctg
    50701 atgtttatca taccccatca gacaaaataa gtaaaaattc acaatgaaaa ggtaaaacca
    50761 caaaggattg tgtaacaata catccattac tcttcttcca actttctgtt aactactatt
    50821 tctaagcttt ttcttctttc tttggtgaat aaactgttaa tccttttgat acaacagata
    50881 attcaactgg aagatcatct gtcgtgtctc catccgttcg agtgcccaca gatttttcct
    50941 gcgcttggat tttcatgcgt ttggctgtga aataagtaat gccggggatc gtatagaatt
    51001 tgcctctcat gattctaggc aaataaaaaa taaatcggaa aatatctaag gaaggtacga
    51061 tcgttacatg aaattttcca tcatctaggg tcgctgagtc gtcaaaattt gtaaaaccgc
    51121 ccacggagtt agacatcgtg actgtcaaca gttgggattt tcctttccaa tgctcctcgt
    51181 ctgtttctaa atccaaatga tattttttct tcttcagcaa taacttaaaa aacttcttga
    51241 taaagatcca cgagccgtaa cgctgttttt cttcttgact gatccaaact gctgtatctg
    51301 ctaagattcc gattgtcagt gtagagataa tgacttcatc attgacttga ccatagtcta
    51361 ttttccgtac attgccttcc aggatcacgt cagcagcttc ttcttttttg aggggaatct
    51421 caagaacacg tgcaaggttg ttgacagttc cacctggaag taatccgaca tggtattgag
    51481 ataatgtttt ttggaacgct tggacgatat gatgaatcgt gccgtctcca cctataatta
    51541 ctaaagtatc agcttctatg gcttctgctt tcttgactaa ttccgcatca tcaatcgatg
    51601 ggccagtttc agctagttct acatataatt ctggctgctt ttcttttaca taatcttgaa
    51661 accagcgtgc taatttctca ccctcatctt tccctgaact tttgttataa aaaactagca
    51721 gcttttccat tctttacctc ctatttactc ttcaaaaaag agggcgggac aaccaattcc
    51781 attgtcctgc cctttagcct tagacagatg acattccatc attgggacga acgccttgtc
    51841 ataagctgtt ctttttcgat tttaactctt tgtgttcaat tctgcaattt ttacaatcac
    51901 gtctgttgct ttttccatta cttgtaaaga aacaaattcg aatcgtccgt gcatattttc
    51961 tcctccggca aatagatttg gcgtcggaat acccatgtaa gagatttttg aaccatctgt
    52021 tcctccacga actggttcga tcactggaga gataccaagc tcgatcattg cttgtttcgc
    52081 taattccacg atgctcatat ctttttcaat gatttctttc atgttgtaat attgatcata
    52141 catatctact ttgattcgtt cttgatcaaa tcgctgattc aactcttctt ggatatgtgt
    52201 gatttgtgct ttgcgtgctt cgaatttttc acgatcatga tcgcgaatga tataactcat
    52261 agaagcttct tcaggattcc catccaatgc catcaaatgg aagaaacctt cgtatccttc
    52321 cgttttttct ggaacttcat cggctggaag ctgattatga aaatcgattg ctaactgtag
    52381 agcattgatc attgtatctt ttgccgtccc tggatgtaca tttttccctt ggatcgtaat
    52441 atttgcttga gcagcactaa acgtttcata ctgcaactca cctaaaggac caccatcgac
    52501 tgtataagca aaatctacat cgaattgctc aacatcgaat ttatccgctc cgacaccgat
    52561 ttcttcatca ggaccaaaag ccactttgat ggtaccgtga gggatagaag gattattgat
    52621 caagatctcc attgcagtca tgatttccgc aatccctgat ttgtcatctg ctcccagtaa
    52681 tgtactgcca tctgttgtga tcaatgtgtg gccttcataa tttttcaaat ttggaaaatc
    52741 ttttgtattc aatgtatagc gttcttccgc atctagtacg atcgtagact cgccatcata
    52801 gttttcaatg atttgtggat tgactcctac tgcattaaaa tctgctgtat ccatgtggga
    52861 aataaatcca atggaacgca cttcatgatc aacattgctt ggtaatgttc ccataacgaa
    52921 tccgttatct tcattataga aaacatcagc taagcctaac tcttctaatt cttttttcaa
    52981 ttcttgcgca aaagcaactt gtgtctgagt cgatggagtc gttttgcttg ttgcatcgga
    53041 gcgtgtttct gttttgacat atcgtaaaaa acgtggcaaa agattttcgt acatagtatt
    53101 ctctcctttt aattaaattg aaatgggttt gtatttgttt cagaaacgaa aaagttaata
    53161 tcccaatttt cttcttgttt ccaagattca aatttctcga taaatcgttg cttgcataac
    53221 gattcaatat aatgaccggg atcaattgca atcaacccag cgctttgcat atcatgagcc
    53281 gtatgataat agatatctcc cgtgatatag acatctgctc tttgggcgat tgcttgcgga
    53341 taaaattttt caccgcttcc accgcaaatc gcaatgcgct tcacagagga ttttgcattt
    53401 tttggctgga ctattctcag tccatctagt tggaacgctt cttttacttg ttctacaaat
    53461 gcctctatag aaatttcttg cggcaattca cctactcgtc ctaacccaaa catttcgact
    53521 ggttcatcta tagcgaaaag atcataagca ggttcctcat aaggatgagc tgaccgcatg
    53581 gcttgaatca cttgtttttc gatagtttcc ggcaaaataa cctcaacttt tgcctcttga
    53641 acttgttctg tcttccctac tttcccaatc gctggttgtg caccagcttc cggagtaaat
    53701 cgaccgtgtc caatcgaggt aaaacttgta ccggtataat caccttgtgt accagcacca
    53761 gctgcagcta atacttcacg cattttctgt gcatgatcca caggtacata aacggccagt
    53821 tttttataat gaatctcatg agtctttact aaataactct ccacttcaat accgagaagt
    53881 tcacaaaacc agtcattcag tccatcccaa ataatatcca tgttcgtgtg tgctgcatag
    53941 acggcaatat catgtttcaa caaatctgca tacatttttt cttgtggctg atcagtaacc
    54001 agccgtttta caggacgaaa gattggagga tgtttagcaa tcagcaaatc gatttttttc
    54061 ttgattgctt cttcgaccac ttctggacga acgtctaatg tcatcattac tcgttggatt
    54121 ggcttatcca atgttccgat atgcagtccg actgggtctc cttcttcagc tagccactga
    54181 ggacaatagc tttcaaactt ttggatgaaa gtgcgtccgc tgattgtcat ggctttaaaa
    54241 cctcctcaat catttggatt tcctgctcga tttgtttttg acgtgcctct tgattagctg
    54301 cttgtttgag ctgttcacgg atagcttttc tttgttgaag ctctcttgtc cattttgatt
    54361 tgaagatctc acttttctct tcaagcagaa atggcccgaa catcagctcc atttcattgt
    54421 aagtaactgg tttttgttct ttttcggcta caatgatttc atatattttt ttattttctt
    54481 caagtatttt ttctgattgg attttatact gattttcttg cagccaagat cgtaatgtac
    54541 gctctccgat gtttggctga aggatcaaac gttcttgtcc gcttaagcgt tgattcaact
    54601 tgccagcttc taggatatct cggatcagtg aacctcccat acccgcaatc gtgacagctg
    54661 taataccatc ttgtggctgg atagcatcta gaccatttgc aaggcgtacg gtgatacggt
    54721 cttctaatcc atcttttttg acttgcttac gtgctgattc ataaggacct tgaacgactt
    54781 caccagcaac tgcatattcg atttttcctc ttaatatcaa tgcaacgggt aagtaagcgt
    54841 gatctgatcc aatgtctgct aaacgagcgg attcagggac aaagtcaccc actgcggcta
    54901 agcgctgaga taaatctaaa tggttcatag cttcactcct tctagataat tatagcattt
    54961 tccaaataaa ataaggagac taggaataaa aaaattccca tatctcctta aaaaatatac
    55021 cttttcgttc tataaaacaa cattttctta tttttgaaaa aatgttattg gttatttgtt
    55081 caatgaaaca tcaataatcg aatctccagg aacttgcggt gggatagaca tcgtcatgat
    55141 cggcatctca actaatgtaa attggacttt gtcaccgatt ttcaattcat ttatgtccac
    55201 gcttattttt tcagcagtag catttaagat cactccgtca ttgctgaatg acggtcccat
    55261 attcgctgga tcttctttgg ccatgacatc gacgagtttc aactgaagcg tttcttcttc
    55321 tgcttctact tgagtgatac tttcaatcgt tccgacaaat atgctttgtc tctccgtttt
    55381 cgtactgctt gtttttactg tttgacccgc atcaatcgaa tcaacagaac ctgtgttgct
    55441 atctgcgcta ccgcagcctg ctaaaagaaa aaatagacca actacagata tactagaaaa
    55501 aatagccctc ataaaaaatc ctccgtttaa gtttctgcat tacttgttgc ggtgattgtc
    55561 tccggtcatt tctgtccata taatgattcg ctgacctgct tttactacta ggtcaaatgt
    55621 cagttggact tgtcaactgt tcaaccattg cgtcggttgc gaccagtcat ttcgatttct
    55681 tttgtcaaat aacgtatgcg ttccattatc cgtttcgctt ttagcggctc ttcatctcca
    55741 cgttgagtga cggacaaatg ctgttccaat tcatccattg taaaattcga tgagaagaag
    55801 gttggtaact gttcctgcat ccgatattga aggataacac cgaatacttc gtctcgtatc
    55861 caactactca tcgcatctgc accaatgtca tcgatcatca aaataggtga acgtttcact
    55921 gcatctaact tttctgccac ttgatctttt ccgattgcct gtttcatctc aacggcaaat
    55981 gtcggaaaat ggactagcgt cgtggtgaat ccagcaatcg ctaattctct cgctgttgct
    56041 cctaataaat atgtttttcc aataccaaaa cttcctacta gatacagtcc tttatgatac
    56101 ccttttggat cagcagtata tttctctaca aaatctaggg cttctaagct cgcatatcct
    56161 cgtccatctg tacgttcaaa gttttcaaaa gaagccgatt gaatatcttt tggcatatcc
    56221 attgctttta ctcggcttct gatttcttct tgtctttgcc gtgctaacaa tgcttccgtt
    56281 ggtacataag tgacatccac ataatgaaaa ttcaacgtca gcttcggctc atagccggga
    56341 gcgatcatcg ttggatcgtt tttttgatat ttacgctttt cttgcacgaa ttcatacaat
    56401 ttagcgtaac ttttttcaat atccgcttgt gtcaattctt cttggtgtgc gcttagaaaa
    56461 gcttgaacat ccgcatcatt taagacttca gcgatcattt cagcatactt ttcttgataa
    56521 ttgcgtttgc tgatgatcct cttcaattct ttgcctacgt cttccactag atatcaccct
    56581 ccttttttgc caggtattct ttaaaacggc ggtcaatctc tgcttttttc tcgctgctga
    56641 tctgtttttc atcttttggc tggttgaccc aatcaggaag cttttcccgt cgaacatttc
    56701 gcttgccagt ttgataattt gtttgcttct tttgttttga ttgttttgct tgattactta
    56761 tttgccgaat gtgctggatc gcttcttctg ctgtggcgat tttcttttgt gcccattcat
    56821 ttgccactgt atttacataa ctggcattta agctagcatt attcttgatc actagtacat
    56881 aattcagcaa aacattgatc acgctactgg aaagacctga ttgagaaaca agatcttgca
    56941 gtaaccagtt ttcttgttta gaaacatatc cgcctttttc tgacttgatt gcttccagat
    57001 atttcatcgg tggaatgctc tgtgcttctt ttatcagctg aagcgctgcg tttgtcaaat
    57061 gttcgtttga cgagggttca ttactgtttt cagaaaccgc aactgtttct tttgtttgct
    57121 tcaccggacg tctctgcatt gccaaaatgg ctttttgcag ttctttttca gatacttttt
    57181 gttcactaaa gtcataagat tgactgatca gttcgccaag tgtcaattca tcgaaaccgt
    57241 aaagctgatg atacatgtcg acttgtttga tgattggatc atcaagactt gcaatatgtt
    57301 tttttgccag ccaatcattc aaaaactgcc aatcgaatgt cgaatctgct tcaagtaatg
    57361 ctactgattc agattcttca aaagatttat tcagcgattc gatgttttct tgattagcag
    57421 cgtacactgc ttcattgaag cgataaacat ctaaaaattt ttttgtgatt ttttgatatc
    57481 cctctgctgt atgcctttta ggttcaaaga attgggtaag cttctggaat cgtcgttcac
    57541 caactttttc cagaagaaga aaagccagaa cagagtcttt gaaaaatgct ttaggaatga
    57601 gtggttctaa cagctcataa ataaaacgag gtcccagatc actatcttct ttaaaataaa
    57661 catccagtaa gccgattcct tctagctttt ttcttgcatc ataaaattgc gggataccgc
    57721 agcctagact actaagcaga tctgcatgca tcccttcagg acctttgcca gattcttgag
    57781 agatttctga taacagggtg aaatagatac tcaaggcttc tccgccgatt agtggctgat
    57841 aaagatacag caaggcgttc ttgctgtctt ctctcagcgg agccgctttt cttccttggt
    57901 aaatattttt tggttgaagc tctttccaag cattttccaa ggaaatgcct cctttttgtt
    57961 tcttaattgt tttctttatt attctcttta ttattttctt ttgctttatc cacgatatct
    58021 tgcaactctt ttaagaaaac agacatatct ttgaactggc gataaacact tgcaaaacga
    58081 atataagcga tttcgtctaa atcaactaaa tcttccatca catattcacc aattagattc
    58141 gtcgatactt cgttttctcc gagactgcgt acgcggtttt cgacatggtt gacgatttgt
    58201 tccatttgtt ccatagctac aggtcttttt tctgctgaac ggatgagtcc tcttaaaatt
    58261 ttatcgcgat tgaactcttc gcgttccccg tttttcttga ttactaataa cggagcagct
    58321 tcaattcgtt caaatgtagt gaatcggaac gaacaattct cacattcgcg acggcgacgg
    58381 atcgcacgtc catcatctgc ttgacggctg tcgattactc gtgaattatt atgttgacat
    58441 ctgggacatc tcattttgtc tcacctcttg catcgcattt tatataaagg atgtgtcttt
    58501 ctttacaact agttgtatta taacacgaaa caaatcacaa acgcgactgt cctacccaaa
    58561 aaacacggat ataagaacaa ttttttctac tttcatgcgt aattgtgtcc cctgtcctta
    58621 ctaaatttca attttccaat actgatcacc ttgattactg agaaataact tacacaaaag
    58681 ctgatttagt catctagcac aaaaaacttg aagcagatga acaccttctc atctgcttca
    58741 agtcacatct cgatttttta ctattttata acttctcttc gattcctgta tagtgtttca
    58801 ttcgctgttc ctcgattttt tgctcatcgg gaatgtggtc actttctggg agcggtgttt
    58861 tactacgatc aggtgtcgga ttttttcgtt cttgagtcaa atcttgccgc ttcgcttctt
    58921 cttctgcctg ctggtcttct atttcatcga ttcttgcttg gtactgcttt tctttttctt
    58981 ctgctgtttc tgattgcgta cgaccttcat cgattagatt ttctttattg agcatctcgc
    59041 cgattttttc ttttgcgtta cctacgactt tatccttttg attttttaat gatcccatcg
    59101 ctatccctca ctttctatat actcaggata gcaaaattga cacagatact caaagaaagc
    59161 gattagcaaa aagccaattt tcgatttgtc ccacaagtat ttcttttgtt ccattgttgt
    59221 cgaacaaaat atccgcacgc tgcttttttt cttcgattgg aagttgacta ctaattctct
    59281 gctgcgcttg ttctagcgtc agttgattac gtttcatcaa acgctgaagc tgagtttctg
    59341 gcgtagtata aacgacagct actgcatcca tatagtggtc ataatgacct tcgtagagca
    59401 atgggatatc tacaattact aaaggatgat tggaacttag agaggcgatt tgatctttta
    59461 tcgcttttcg gataaacgga tctaatagct gatcaagttt ttgccgtttt tcctttgatg
    59521 gaaaaacaat catcccaagt ttccctcgat ctagttgccc atcaggctgc aatacctctt
    59581 ggccaaacac tgatacaatt ttcctcagag caagcgttcc aggctcaaca gtttctctgg
    59641 caatcacatc gccatcgatc aaaggaaatc catgagactg aaagactttg gctgccgtac
    59701 ttttaccggt agctattcca cccgtcaaac ctaaaacaaa tcctactttg cgatttttag
    59761 cctttgacaa ttcggacaat agtgcgtccc cctttgtgcc acttttgttt tcacgatcgg
    59821 cgttccacaa cgtatacatg gtttgccagt ttgctgatag acatgcagtg ctacttgaaa
    59881 tccgcctgat tctcctaatg cattcaaata actgcgaatc gtggtacctc cggcttctat
    59941 tgcacgatcc aaaacatcaa tgatcgatag acgtaattgt tctacctctt tggggcgcag
    60001 tgtgttcgcc ggttgttctg gatggatctt cgcttcccat aatgcttcat ctacataaat
    60061 attacctaga ccagtcacta gacgttggtc tagcagcaat ggcttgattg ctttgtggga
    60121 ctttttcagt ccatttgcga aatctgctaa taagaagcta tctggcaaag gctcaggtcc
    60181 caatttcatg attcctcggt aagttgcact tgctcctttt tcgacgattg tcatacgacc
    60241 aaattttcgt acatcgttgt agcgaagttg gcttccatcc tcaaaaaaga aaagtacatg
    60301 cgtatgttta tcgattggtg tattttcttt cgtaaattga tattttcctt ccattcgcaa
    60361 gtgtgagatc agttcacaat gatcgagatg aaaaattaaa aacttccctc tacgtccaat
    60421 ggattggatg gtttcgccaa caagagaagc ctcaaagatg ggtgtctctg gttgctcgat
    60481 gatcttgggc cacaagacct gaactttttg aatcgttttt cctactacta accgttccaa
    60541 tcctttacga acggtttcta cttctggtaa ttctggcatt ttttcttttc accttcatta
    60601 tattgctctg tcttaaacaa tgtttatttt gcttcgtacc acgtttttcc ccaactgctg
    60661 tcagtgatca gtggtacatg aagagaaaca gcttgttcca taacttcctt caccaattta
    60721 tctaatgatt caagttcttt ttccggtacc tcgaagacaa gttcatcatg aacttgtaac
    60781 agcatcgtag cttgaagacc tgtttctttt aatcgtttat ccaattcgat catcgcgatt
    60841 ttcaaaatat cagcagcact tccttggatt ggtgtattga tagctgttcg ttccgcaaaa
    60901 gaacggatat tgtaatttct tgaattgatg tctggcagat atcgacggcg gtgatacagc
    60961 gtttcgacgt agccttggtc ttttgcttcg cgtacgattc tttccatata ttctttgaca
    61021 cctgggtatt tttcaaagta cgtatcgatg tattgctgtg ctgcttttcg gctgattcct
    61081 agattttgtg aaagtccgta atcagagatg ccatacacga taccaaaatt cactgctttt
    61141 gcctgcctac gcatatttgg tgtgacatcc tctgcctttt cgattccaaa tacacgcatc
    61201 gctgtgctgg catggatatc ttgaccttct aggaaggcag ctttcaaatg ttcatcattt
    61261 gagatatgcg caagtacgcg taactcgatt tgtgaatagt cagaagaata aatcagccag
    61321 tctttttctc taggaacaaa tgcctgacgt atctttctcc cttcatctaa tcgaatcggg
    61381 atgttctgca aattaggatc aacagagctt aatcgtcctg tttgggtcaa tgtctggaca
    61441 taacgggtat gcacttttcc atctgattgg atcactttca gcagtccctc gacataggta
    61501 gattgaattt ttgcaatttg acgataggtg aggatatcct ctacgattgg tgcttgttca
    61561 cgaagctgtt ccagtacatc tacggctgtg gaatatccag tttttgtttt tttgataacg
    61621 ggtaatccca ttttttcaaa taagatcact cctaattgct ttggtgaatt caaattgaat
    61681 tcttcgccgg cttcttcgta gattttttgt tcgatctctc ttaagcgagc agagaactcg
    61741 cccttcattt cttgtaagcg agtcgcatct actttgatcc cgcttatttc catctctgcc
    61801 aaaatgatag acaatggcag ttccattttc cggaaaagat cttcttggtt tttttctgcc
    61861 agttcttggc tcaattttgg tgtcaacgca ttgattgcag ctacttttcg cgctaaatga
    61921 gcaaaaaaga gttcctcttc ttctggtaaa ccttttttcg cccctttgcc gtatacagct
    61981 tcatctgatt ggatatcgtt gtatccgtaa tgagcagcta ttccttcgat atctgtgctt
    62041 ttttcattcg tatcgagaag gtatgcacct agcaagacat caaaatcgat tcctttcgtt
    62101 tttccagtat agcggtttaa agcaacataa gttcgtttcg catcatatac ttttttcagc
    62161 cgagtcggat cagtgatcca agaatggaac gctcggtttt cgaatacaga tagatcgttc
    62221 gtgacataaa ttttcttttc tgtcccccac gctactccga cgatttcctc tgtatgataa
    62281 ttgtcgccca tcatttccac gtacaacgcc atatccgtag taaacatttc ctctttgaat
    62341 tcatgaacga cttcaaacaa aatatcatcc atttttactt cttcttctac gatattcaat
    62401 ttagaaagga actgattgaa atccatttct ttataaaacg gaacgagttt atcgagattt
    62461 ttcccttcat acttcaatga gtcgatagag acatccacag gcgctgaagt attgatggtc
    62521 gccaattttt tcgataagaa agcctgctct ttgtcattta tcagattttc tttcattttg
    62581 ctttgcttca tttcatcgat atgttcataa attccttcga ctgagccata ttgtttcaat
    62641 agcttgatag ctgttttttc accgatttta gtcacaccgg ggatattgtc agaggcatct
    62701 ccggctagtc ccttcatgtc aataatctgt tttggcgtca acccatcata tttttccgct
    62761 acatgttctg gtgtatagct ttcgatatcg ctgacacctt ttacagtgat atccactttt
    62821 acttctttac tagctaattg agtcaaatcc cgatcacctg aaagcacgac gacatcaaat
    62881 tgatctttgt ctactttttc tgccaaagta ccgataatat catctgcttc ataattgggc
    62941 aattcgtaat actgtacccc tagtcctgtc aacaaatcac gtatatatgg catttgttct
    63001 ttgaattcgc caggtgtttt ggatcttcca cctttgtact ccgcatacat ttctgtccga
    63061 aaagtcgttt ttcctgcatc gaacgcaacc agaacatgag tcggttgctc tttttgcata
    63121 acattttcaa acatcgtatt gaatgcatag attgcatttg tatgaagacc gtttctattt
    63181 ttgaaacgtt caagagaatt gtgaagcgca aagaatgcgc gaaaagccac actgttccca
    63241 tcaacgagta ataatttatt ttttgtcatc ttcttaactc cttactgtaa agttcttatt
    63301 cattctaaca aagaatcctg cggaatgcga aaagaaaaag cgggaccata ccaaataatt
    63361 cggtatagcc ccaactgatg aatttttttc ttttttagtt gttccgtcca aagattctca
    63421 gaaacgccaa gaacaagttg ataaagtcca aatacagctt caatgccatg aatacagcaa
    63481 ttccactatg tgctgttccg tttgtctgga catagatatt acggatgctt tggttatcat
    63541 aagctgtaat ccctgcaaag atgacgacta acagtaggga gatgaacagc tcaactacgc
    63601 tacttctcaa aatgaagatg ttcaagacta gtgcaatgat cactccgatt aaagctgcct
    63661 gtcctgctct tccaaccccg ctaagatctc tttttgttgt tactccgaca acagacatcc
    63721 ccatgaacat caaagtagct gtcaagaaag cttgcgttac tgttccaata tcgtagtatg
    63781 caagagtaac cgctaatgtt atgccattca aaagagagta ggcaataaat ccaccgattg
    63841 ctaagctcgg attcttttgt gcttttacgc ctagaaccat tactaaaatc agttcaacga
    63901 tccacagacc cacaaagcct agtggaaaat tattgataaa agttgctaat tgcaaaggaa
    63961 atacccaaag agccaagtaa gaagtgactg cactaagggc aagtcccata cctaaaaatc
    64021 cataaacttt tgcataaaaa cgattgatac ctgacattga tgtacttgga ttattcattc
    64081 aattcacctt cactttcgat tgctatttcc aattcaggaa cttgtggcgg ttggaccata
    64141 acgacagcat ccaacacacg atcttcgttc gtattctccg cttctacaga aatcgtcacc
    64201 acatccttca tcttatctac ttttatgacc tcaaactgaa aagtcagtgt ttcataatgg
    64261 aaaaccggtt caataaaatt gacagaaaaa ttgacaacat gtgatcctgg tccaggaaga
    64321 tgctttgaaa ttgcacttgt gatgatcccc atcagcatca ctgatggaac gattggctgt
    64381 tgatattctg ttttttgtgc aaagtcatgt tggatataca aaggatttgc atcattcgtc
    64441 aatcccaaat acagcaaaag ctggttatct tcaatagatt ctgttaagga taacgagtcg
    64501 ccttcctcga tttcatttat tgtttttcct agttttctcg gcttacctat gttcaagata
    64561 gaaaccctcc agtttatttt taatcataca ttattgtacc aaaagtagcg taaaaggcaa
    64621 gttctgctcc cttgatttaa cagattccta tagtttacag aggtcgtgaa aaagctgtcc
    64681 tgcatcaaat aataagaaca gccaagaaaa aacagcttct catgtttttg atttgattgg
    64741 gcttattacc gcagatgcaa gcttttgaac accgtttatc ataagttgca aaaaaggggg
    64801 cttggcaaga tttttgccac tccccctctt tctattttta taaggacact gcagtaattg
    64861 tattacagta catttttcgt cgtgctgctt aaaagttttt catacgcttg ttcaaatttt
    64921 tgaacatctc cagcacccat gaagattact actgcatcat gataatctaa caatggagat
    64981 acattatttt ctttgatgac ttctccacct tttttgattt tcgctccaag gtcttcaatc
    65041 ttaacgtttc cttgttcttc ccgagccgaa ccaaaaatat cgcataagta aactttatca
    65101 gctaaatcaa gtgcttctgc aaattcatcc atcaatgcaa tcgtacgcgt aaacgtatgg
    65161 ggttggaaaa ctgcaattat ttctttatct ggatattttt ggcgtgcgcc atcaatcgtt
    65221 gctttgatct ctgcagggtg atgcgcataa tcatcgacta cggtcatgtc tgctacgatc
    65281 ttttcactga atcgacgttt tactcctggg aaagtcagca tttcttctgc aacttctttc
    65341 agatccagtt tttcgaaata agctactgca ataacaccta aagcatttaa gatattgtgt
    65401 ttaccgaatg ctggtacagt gaagtgccca acaaattcat ccccatgata gacatcaaaa
    65461 gcagaaccag aagttgtgcg ttcgatgttt cgtgcttgga tatcatcgtt ttctgtgaca
    65521 ccataataat aaatcggcac atttgctttt aatttgcgta aataagcatc gtcaccatac
    65581 gcaaaaatag cttttttcac ttgtccagcc attgtttgga aagctgtaaa tacatcgtcg
    65641 atacttgtat aataatccgg atgatcaaaa tcgatattgg tcatgattgc atagtctggt
    65701 gaataggcaa ggaaatgacg gcgatattca caggcctcaa atgaaaagaa ttccgcttgc
    65761 ggatcaccat gtcctgttcc atctccaatt agataacttg ttggacggac accactcaat
    65821 acatgagaga gcagtccagt cgtacttgtt tttccgtgag agcctgttac agcgatactc
    65881 gtataatttt ggataaaatg accaataaag tcgtgatagc gaatcacttc caaacctaat
    65941 tcttttgctc gctggatttc ttcatgtgaa tcaggaaatg catttcctgc aatgatcgtc
    66001 atccctggtt ttacattatc tgcgttaaat ggcagaatcg tgatatttgc tttttctaaa
    66061 tctctttgtg taaagaaata tttttcaatg tctgatcctt ggacatttag accttgttca
    66121 tgtaaaacaa gagccaagga gctcattcct gaacctttga taccaacaaa atgatacaat
    66181 ttattttgat tttccatttg aatcctcttc tcttatctag cgtccattct tttagctatt
    66241 acattcaaca cgctcctcat tatcttataa acgattgaaa atttcaacca aatttatttg
    66301 gaaaggagga ttcgcttgct aaaatggtca agtacgagaa aaatccgttt ttattgactc
    66361 tttaattctg gtgtaagaag accaaacttc ctctgatata tcaatgtgag gaataaaatc
    66421 ttttcctttc ggaccatagc cgttctcatc gtcatggaga cgttccattt ctcctaatac
    66481 tagcgcatgg aaatattcct taggccattg atgattcagt tcttttgctg taaagatgat
    66541 ctcttcagaa aagtgaagga tttccggcac aaatggcaca gcattcgcga aaatagtttg
    66601 ttcattttgc catactttct caaaagttgc tcgagtcctg cgttgcagtg tcggatcatt
    66661 catcaataag attttttctg gtacagctcc taaggaatga agaatctcca gtgaaaaagt
    66721 ggcgttctct ccagaatttg tagacttcga ttctatcaga aaagccttat cgggcaaatc
    66781 atagacttct tttagatact gacgacagat ttcactttca ctcatgccat cttcaaaatg
    66841 aaatccttgc ttttcaaaat tctcataaag gattctagtc gcatgcccca cccctccgac
    66901 caaaaacaat tgatctactt ggccatttaa atacatttgt gctgctttat cagctaagat
    66961 aggaagacag tttccagcta aaataagtgt aggtgccgtc agttcctcaa aatttccctc
    67021 ttcaggtgcg gctaaaaaat ttaatagctg attccagtct tttagattcc tctgctcact
    67081 tttttccaaa ggccttctat cctttcatct gattttttgt gcttcattaa agtcttctct
    67141 ttttgtctca atccatttga tttctccatg acatcttcca caacgatatt tgcgtacatc
    67201 gattcttctc ttgcggcaga tcgtggcaga acaatcttgg catcgataat actccatctt
    67261 tatctgtttc ttcgtcaagg ctggtgcata gcgcaaccct cctgtttttt tcaaaagata
    67321 cttgaaatcc atatctttat gctgataccc tcttccagct agatgaagat gataatggca
    67381 aagttcatgt ttgatgattc ctgcaatcgt ctcttcgtct gactcttcaa atagcttcgc
    67441 attaaaatct aaatgatgat cgtttaaatg atagcgcccg ccagttgtac gtaagcgtgg
    67501 attgaacatt gcttggtgct tgaaaggaag ctggaagctt tttaatgata tctcttctac
    67561 taactgctgc agttcttctt gtgtcaattt ttgttactcc tcattgttac tcttcataag
    67621 gggaaagcat cgtcaaactg attctgcctt ttttcgtatc gacttgttct atccaaactg
    67681 ttacgatatc tcctactgac acgacatctg taggatgctt gacgaatttt ttgctgagtt
    67741 tcgatatatg gacaagtccg tcttgcttca caccgatatc aacaaatgcg ccgaagtcaa
    67801 tgacattacg gaccgttcca gtcaattcca tccctggttt caagtcttcc atactcaata
    67861 catctgtacg taataagggc gctggcatct catcacgcat atctcgtcca ggttgtgtca
    67921 gcccagctaa aatatcggct aacgtttctt ctccgactga taggctttca gccagtttct
    67981 ctacggataa tcgtgtcaat ttttctactg cttcttctgt accaagctct ttttctgaaa
    68041 gttggactga agttaatatt tcttttgcaa tagaataact ttcgggatgg atacctgtgt
    68101 tgtccaaaat gtttttccca ccagggactc gcaagaatcc gattgcttgt tcatatgctt
    68161 ttggtcctaa gcgtggcact tttttcaatt gagttcgtgc ggtgaattct ccgttttctt
    68221 cacgataaat gacaatgttt tgggcagttg ttttattcaa tcctgatata tgctgcaaga
    68281 gctgcgggct tgctgtattc acatccacac ctacttggtt aaccgctgtt tccacaacaa
    68341 aatccaattg ttcagccaaa cgtttttgag aaacgtcatg ttggtactgg cctactccga
    68401 cagctttagg atcgattttg actaattcag ctaaaggatc ttgcaggcga cgggcaatag
    68461 aaacagcact tctttcttca acttgtagat gcggaaattc ttttcgtgca atttcgctag
    68521 cggagtaaac agaagcgcct gcttcgttga cgatagcgta ataggtttta tggtcggcgg
    68581 atttcaactg ctcagccaca aaaagttcag attcccgact ggctgtacca tttccgatag
    68641 ctaccatatc tacttgatat ttattaatta attggataaa agctggtcca gcagcttctc
    68701 tttttgcttg cgctgcaggt ttatgaggat aaataacttc gattgctaaa actttccctg
    68761 tcgcatctac gactgctagt ttacatccag tacgataagc cggatcaaat cccaggacaa
    68821 ctttaccttt tagtggcggt tgcaacaaaa gattacggag gttttcgccg aaaatagcga
    68881 ttgcttgctc atctgccttt tcagtcaatt cattgcgcag ttctcgctcg attgctggct
    68941 gaataaagcg tttataacta tcctgatagg cttctctgac gaatgaagaa gaaggagagg
    69001 caggattttt gactatttgg cgatccaagt aagctaaaat tgctgcttca tctacttgaa
    69061 agaatacttt cagaatatct tctttttctc cacgattagt agctaatatt cgatgagaaa
    69121 ccattttatg gacgggttct gcaaagtcat aatacatttc atatacgcct ttttcatctg
    69181 cttgctcatc cttgacattg ctgacataca tacctttgtt atacgtataa gaccgaatcc
    69241 aagtccgaaa ttttgcatta tcgctgactt gttcagcaat aatctcatga gcaccgtgca
    69301 acgcttcttc ggcagaagag acttcttttt ctttgtcaat atatttttct gcttcagatt
    69361 gcacctctcc atctgtaagc tgcatcagcc acttcgcgag tggttcaagt cctttttctt
    69421 tagcaatcgt tgcttttgtc cgtcgttttt gtttgtatgg acgatacaaa tcttccactt
    69481 gttgcatttt cacggcttgg gtgatttctg cttctaactc gggagtcagt ttcccttgtt
    69541 catcgattag ccgaatcact tcagttttac gtttttctaa gttttcaaga taggcatacc
    69601 gctcttcgat ttcacgaatc tggacttcat caagacttcc agtcatttct tttcggtaac
    69661 gcgcgataaa aggaacagtg tttccttcat ttaacaaatt aagtacagta gtcaactgct
    69721 taggacgata gtctgaaagt tctttttgta caagctgaat gatcgtctgg ttcaaatttt
    69781 ccgtcattaa aatgcctctt ttctgctaaa aattgcttct ttattctatc atacttttta
    69841 tcctgggtta aactactgaa agaaacaata ttctctataa aaataaaaag agccgcaaca
    69901 aagtcacagc tccttcattc tttccattag tcagattcca tgccaaggtc cttcgttgtt
    69961 ctgatattca atatcttgaa gaataccttc cttgtcaaaa acaaccccat gcaatgaccc
    70021 tccgaataca gccccaccgt ccattccgat tttatgatcc tgaatccaga ggtctgttgt
    70081 ctgcatatct ccatggagca ttggtgtaat cgtatgtcca aatacaattg tcttacctgt
    70141 attgtttttc ccttcatgaa atggttccct tatccaaata aagtctctta gacttgtctt
    70201 acgccagtct ttctttgtca aatccacacc ggcatggaca aaaagataat tttcccattc
    70261 ataatacaag gggcgctgga ctaaaaattt aatcagttct gaatatctcg attggatcat
    70321 catcgagatt tcagttgggg agtattcctc cgatgcccct gggtgaatca ggctttcaaa
    70381 cgtttctttt ccaccatttc tcatataagg cgcataccag tcctccggtg attgcagaaa
    70441 ttgcaaaaaa tattcttcat ggtttccccg gaggtaaatg gctcctgttt cttcgactaa
    70501 ttgctttcct aataaaaaac attcttttgt acgaggacct cgatcattga gatcccctaa
    70561 taaaacaagc tgatggatct ttggatcata atagtgaata agtttttcaa aaagctcatg
    70621 tttgccatgg acatccccaa tagcataaat caatgatttc atgtggatca ccatcctcaa
    70681 cgctagtata gcgcatattg gaaatggtcg acaatcaaaa ctattgtttt ctatttaatt
    70741 aaagctgtaa accgcagttc tgcttcttct ggagagattc catggtcttg aacatagcga
    70801 ttgcgcggat gtttcgcaca ctctatgcta catgctccta aatgtttttc ttcattttca
    70861 atggaagcaa gaatctgacg attgcactca ggattgctac aattgatata tcgttcacat
    70921 ggtgttccgt caaaccagtc gcgaccgacg atttgtttat ctacttggtt gatatcgaca
    70981 gcgatccgtt catcaaacac atacatcttg ccgtcccata attctccttg gacttcagga
    71041 tccttaccat aagtagcaat accgccatgc agctgtccga catctttgaa tccttcacgg
    71101 acaagccaac cagaaaactt ctcgcaacga atgccaccag tacagtaggt cactacccgt
    71161 ttttccataa attcttcttt gtgctcgcgg atccagtctg gaagctctcg aaaactgcgt
    71221 atatctgggc gtacagcccc tcgaaaatgt cccaagtcat attcataatc attccgtgca
    71281 tcaatcacca ctgtctgttc atctaaaata gcttctttaa attcttgcgg tgaaagatag
    71341 gcacctgtca cttggtttgg atcaatgtcc tcttctagct ttaaacttac aagctctgga
    71401 cggtatctta caaacatctt cttaaaggca tgtccttcgc ttggatcgat cttgaacatc
    71461 gtatcagcaa atcgaggatc agctttcatt gctttcatat aggcagtcgt gttttcaacg
    71521 gttccagaca cagtaccatt tattccttct tcagctacta gaatacgacc tttaagatcc
    71581 aaagatttgc aaaaggctaa atgatttttg gcaaattcct ctggttcttc gatttttgta
    71641 taattgtaat aaagcagtac ttgataatcc atgtatttct tccttccttc ttttcgttcc
    71701 taaacagtat aaagaaggcg ttcgcatttg acgatttatt tgcttgtgta taattacgca
    71761 tggaaagttt tttgtttaca taatattatt atttgaatta aaaagacttc gctttcctgt
    71821 ttcgcacaga aaaacaaagt ctttatttct attatttacc tgtaaccgca aagtagttgc
    71881 catcgggatc agcaaagtta aagacatatt cttctccaag ctgtaccata tcacctaatg
    71941 tgactgattg cgtctgcatt tttttatata gtccaaagat atctttactg taaaacatca
    72001 aagatggggc actagtagct gtgccaggtg aatgggactc aacaaatgct cgatcatata
    72061 acagaaatga ggtttgactg tcctcaactc ctacttcaat tataagcgtc ccatccattt
    72121 cttgacgatc tttttccgca aagccaactg ctctccaaaa cgttgcattt ttttctacat
    72181 cgtccacata aagcatgatt tttatttcat tcgtaaacat ctgtttcctc ctaaacgatc
    72241 tgttctaaca ttctcaactt tgtcagttta ccataggaaa atgggaaaat ctacgaaagc
    72301 tctcaacaga atcgtcctac ttaaatacgc ttttctttaa taataaataa gttggttgtt
    72361 tttgttattt gcgctttcac ttttcggaat aaataatgtg tatttatatg gaataaataa
    72421 aaaaagaggt cgtgactaaa aacaagtcac aacctctggt aaacggtgtt ctcctgacaa
    72481 ctcctcggtc acaagacaca atattcaaca aacatgagaa gctatttttt gaaattgctc
    72541 tttgtgactc agagtgaaac ggcaggctca cgacctcttt cttaaacggt gttcaaaagc
    72601 ttgcatctgc ggtaataagc tcaaccaaac gtaaaatatg aggaactatt tttgtttggc
    72661 tgttcttatt acttgatgca gggcagcttt ttcacaacct cttattcacg gtgtttcaga
    72721 agtagcttct cggaaataag ccgaaatttc acaaaaattt gagaaactat ttttaggaaa
    72781 cttcttctta tttcttaaag ctgaccactt ctatcacaac ctctttttga ctatgcattc
    72841 acatcgatca ctttagaatc atcattgatg acatcgcgat ctaaatcttt gatgcgtgca
    72901 cttgtcacga taccagctac catgctaccg ctgacgttta ctgctgtacg tgccatatcg
    72961 attaatggtt caacagagat aactaaccca acgattgcta ctggcaagtt cattgcccct
    73021 aaaacgatca gtgaagcaaa tgttgcgccc ccaccgactc cagctacacc aaaagaactg
    73081 attgttacaa ttgccacaag catcaaaata aattccaaac taaagacatt cactccagct
    73141 gctggtgcga cgatcgttgc caacatagct ggataaacgc cagcacagcc gttttgtcca
    73201 atagacaaac caaaacttgc tgagaaatta gctgttgcat catctactcc taaagctttt
    73261 gtctgagtct cgatattcaa tggcaaagct ccagcacttg aacgtgaagt aaacgcaaag
    73321 ctcaataccg gaaaggcttt tttgaaatag ttgattggat tgacttttgc accaatcaaa
    73381 atcagtgagt ggacaatcaa aacagcaagc aatgctacgt aagaagcaac gacaaattta
    73441 cctaaattga cgatagctgc aaaatcactt gttgccaaaa cgtttgtcat caaagcaaat
    73501 actccataag gtgtcaaacg caaaacaagc gtcacgatcc gcataatgat tttatacaga
    73561 ctgtcgacta aatctgaaaa gaatgctgct tcttttggcg cttttctttt cacgcctaga
    73621 taagcgattc cgacaaatgc cgcgaaaata acgactccaa tcgtacttgt tgcacgacta
    73681 cctgctaaat cagcaaaaac gtttttaggg ataaaggata aaatctgctg tggaatcgat
    73741 aagttttcaa ctgtttcctg acgtgttgcc agttcagaga ttcgtgctgt ttctgcagct
    73801 ccttgtgtga atttagctcc ttggagtccg aacagcattg ttgaaccaat tccgatcaat
    73861 gctgcaatag ctgttgttcc aagtaaagaa gtcaatacag tcgcactaat tttccctagc
    73921 ttttcagaaa ctttcatttt tgtgaatgca ccaatgatcg aaataaacac taaaggcata
    73981 actagcattt gcaagaatga tacatatcct tgacctacaa tcccgatcca ttccattgat
    74041 tgagtaacga ctttgtcgtc tacaccaaag atcaattgaa gcagaccgcc aaagacgata
    74101 ccaactccta atgctgtaaa gacgcgtgtt gaaaattttg tatggcgctt ttgcatacga
    74161 tagaacacat ataataatgc cgcaaaaact agaaccacta aaactgtgat gagtgttgtc
    74221 atttttctcc tcctcatatt attaatgaca agtccatcga aggaagtaaa ggttcccgag
    74281 aatgattctt caaccatcct cctgaaaaaa tttttttcag tgacttttat attttagacg
    74341 atttttatcg aaatgacatt ctttttgctt acaattagta ataaaaaaac atacctgtga
    74401 tagctttaat ctatcacagg tatgttttta ctgtctattc ttgtttttct gattgaaaat
    74461 tcaattttac cccaggctga tctaaggcga tctctgtcac ctcataagac attcggcgta
    74521 cgatatcgaa taacggtgct actagctcgt ccacttcttc ttgtgtgaca tcattttgac
    74581 cttcaatttt ccgattgagg atatgattga tctgactcac acttccagat aaaacatatg
    74641 tatcaaacac taaacggaac tctaagcgtg ctcctacgat gctatgttct ttcggatagt
    74701 tttcgatcgt ttcttttaaa ggcgagaagc ctactttcaa atctgtttct acttcttggt
    74761 tcggcaatct catatcataa tgaaatgctt ctacaacttc tttttgtctt ctgatttcca
    74821 tataatttta tcactccttt atgaaaatta taacatatct cctttgaaag gggatactac
    74881 tttttaatga tgctctgcaa ggtaaggatt tcattcagat ttcctaccac ataatctgcc
    74941 gggatctcac ccagaaaatg atcgatgtcg taaagacaag tagcgactcc tgcatttttc
    75001 cctgcttcga tatctaaacg acgatcgccg atcatcatcg tgtctgttct ttctaaatga
    75061 aaagtatcga tcaaataatt taaagatgct ggatcaggtt tacgaggaaa gtcctgatcg
    75121 atccctacta cttcctcaat cagatgtgcc aatcgatgtt cttttaacag gccccatgtt
    75181 gattctgtca aacggtgggt caggatgaaa tgacgaccgc cgttgtcttt tagcatttcc
    75241 agtacttgtt tcgtttctgg aaatggacgg gaaacttccg tactttcttt ttcatatcgg
    75301 tgaaataatt cattaaactc tctggcattc aagtttgatt cattgatcaa ataactagta
    75361 gaatactttt tcattttgaa gtagatttct tttttgtcca tactgatacc aaaatctttt
    75421 agtgcttgcc atgcaccatc taccattgcg ggatacgtat caaacaatgt accatcaaag
    75481 tcccatatat aatttttcat gttccttttg ttccattcct ttgcttcttt tttctatctc
    75541 tcacttttag ataaaggtgt tctttaaagt atttttttgt ccagaattgt caaatcatct
    75601 gctaatgtat actggattgg ttgtgcattt gggatatcga tcgtatccat ttgatcttca
    75661 ggaacatctt ctaaatattt tgtcagtgct cggatgctat taccatgacc cacaactagt
    75721 aaatcttgcc gatcttttag ttttggtgct agatgatctt gccataaggg aatgatccga
    75781 ttcactgtca tttccagact ttctccgtat gggatcaaat gcggatccaa gtgatcatat
    75841 ctgcggtcaa atctattttc tgcggttaac ggcggaactt ccgtatatcc tctgcgccat
    75901 gtttttactt gatcttttcc gtatatttct ttcatcttat ctttgttttt acccacaaga
    75961 tccccataat gccgttcatt tagacgccat gtttttatta taggaagcca taactgaccc
    76021 atttcttcta gtgcgacttg tccggtaaga atcgcacgtt tcaaaacaga ggtataaacg
    76081 gcatcgaatt gaagtccggc ttcaagcatt ttttgaccgg caactgctgc ttgttctttt
    76141 cctttttctg ttaaggcgac atctagccat cctgtccagt aattttcaaa atttgcttcg
    76201 ctttcgccat gacgtaataa tactaatttc attcttttct cccttaaaca ttcgtttcga
    76261 attttatacc acatgttttg catgtcacac gtattcgtcc ttttccttta ggtgcacgct
    76321 gcttttgatg acaattcggg cactcaaaaa aagtataact ttttcgatcc attttgactt
    76381 gctttttgtt ttttatctga tgatattttt ctttgactct atcaagatat ttcaaataac
    76441 gttgattctc atttagtctg gggtagattt tttttgatag gaaacgaaat atcatccatc
    76501 cgaaaaagac gatgaacaac aattgtccga ttctataggg caaccaacga cttagcaaac
    76561 taaagacaag cgcagcgatc aatagaccgc gattcaactg atcaaatttc gcatatcttc
    76621 cctgcataag tttgtgatag ttctgctgaa atcgtattag cctttctaac catgtttgca
    76681 tcatattatc tcctccatca tctaatattt attatgacaa aaaaatccaa aaagaaaaag
    76741 ccttaattgg ccttttccat tgcaacttgg tgaaggacat tccgatttct ggtaaagtca
    76801 atcacaatca ctttcttttt atcttctctg ttgactactc gaaatgtgtc cgtcaatgga
    76861 agaaacagct tcttagatgg tagctgttgc atacgtataa aacgatggat catcgtaatc
    76921 aattgaggaa attgaataga cgtgtgaagc agacctggat attttttcaa cagctgtgtc
    76981 gttttgatca gattccgttt tttactgatc acttttaaaa agctttttag aatcttttgc
    77041 tgacgtctaa aaatagaaaa agaattttcg tcatctattt gataacgcat ttgtttttgc
    77101 agttctgctg cagtcagatg gatcttccca tcgtttgtat cgatcattaa accttctgga
    77161 aacagttcaa ccactgctcg atcccaagat tcaagagaaa gctcgatata atcttttact
    77221 ggtaattcca attctacctt aaaaaagtgc aaaacagccg acagcccttc tgcttgatag
    77281 atttctccta atgttagccc ctctagatgg aactctggtg aaaaatgcag caatgtttta
    77341 ttttcctgca attgaacata tagaaatgta gatcgctcaa tcagagtatc ttttaaaaca
    77401 actaaaaaat tcatttttct cccccttttt tcatcatt
//
LOCUS       DAKCAA010000006        73663 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000006 DAKCAA010000000
VERSION     DAKCAA010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 73663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.006"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(24..1520)
                     /gene="lysS"
                     /locus_tag="OUE31_000461"
     CDS             complement(24..1520)
                     /gene="lysS"
                     /locus_tag="OUE31_000461"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HCU0221495.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1631..2635)
                     /gene="dusB"
                     /locus_tag="OUE31_000462"
     CDS             complement(1631..2635)
                     /gene="dusB"
                     /locus_tag="OUE31_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HCU0221496.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2636..3523)
                     /gene="hslO"
                     /locus_tag="OUE31_000463"
     CDS             complement(2636..3523)
                     /gene="hslO"
                     /locus_tag="OUE31_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HCU0221497.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3740..5851)
                     /gene="ftsH"
                     /locus_tag="OUE31_000464"
     CDS             complement(3740..5851)
                     /gene="ftsH"
                     /locus_tag="OUE31_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HCU0221498.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5941..6486)
                     /gene="hpt"
                     /locus_tag="OUE31_000465"
     CDS             complement(5941..6486)
                     /gene="hpt"
                     /locus_tag="OUE31_000465"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HCU0221499.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6486..7931)
                     /gene="tilS"
                     /locus_tag="OUE31_000466"
     CDS             complement(6486..7931)
                     /gene="tilS"
                     /locus_tag="OUE31_000466"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HCU0221500.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8051..8521)
                     /locus_tag="OUE31_000467"
     CDS             complement(8051..8521)
                     /locus_tag="OUE31_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HCU0221501.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8567..8992)
                     /locus_tag="OUE31_000468"
     CDS             complement(8567..8992)
                     /locus_tag="OUE31_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HCU0221502.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9059..9328)
                     /locus_tag="OUE31_000469"
     CDS             complement(9059..9328)
                     /locus_tag="OUE31_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HCU0221503.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9339..10934)
                     /locus_tag="OUE31_000470"
     CDS             complement(9339..10934)
                     /locus_tag="OUE31_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCU0221504.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10949..14470)
                     /gene="mfd"
                     /locus_tag="OUE31_000471"
     CDS             complement(10949..14470)
                     /gene="mfd"
                     /locus_tag="OUE31_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HCU0221505.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14487..15047)
                     /locus_tag="OUE31_000472"
     CDS             complement(14487..15047)
                     /locus_tag="OUE31_000472"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCU0221506.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15400..16374
                     /locus_tag="OUE31_000473"
     CDS             15400..16374
                     /locus_tag="OUE31_000473"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCU0221507.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16544..17944
                     /locus_tag="OUE31_000474"
     CDS             16544..17944
                     /locus_tag="OUE31_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HCU0221508.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18022..18744)
                     /locus_tag="OUE31_000475"
     CDS             complement(18022..18744)
                     /locus_tag="OUE31_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0221509.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18823..19329)
                     /locus_tag="OUE31_000476"
     CDS             complement(18823..19329)
                     /locus_tag="OUE31_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCU0221510.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19452..21251
                     /locus_tag="OUE31_000477"
     CDS             19452..21251
                     /locus_tag="OUE31_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HCU0221511.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21319..22893)
                     /locus_tag="OUE31_000478"
     CDS             complement(21319..22893)
                     /locus_tag="OUE31_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCU0221512.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23148..23657)
                     /gene="mreD"
                     /locus_tag="OUE31_000479"
     CDS             complement(23148..23657)
                     /gene="mreD"
                     /locus_tag="OUE31_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HCU0221513.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23661..24515)
                     /gene="mreC"
                     /locus_tag="OUE31_000480"
     CDS             complement(23661..24515)
                     /gene="mreC"
                     /locus_tag="OUE31_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HCU0221514.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVASVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24670..25308)
                     /locus_tag="OUE31_000481"
     CDS             complement(24670..25308)
                     /locus_tag="OUE31_000481"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HCU0221515.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25309..25959)
                     /locus_tag="OUE31_000482"
     CDS             complement(25309..25959)
                     /locus_tag="OUE31_000482"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCU0221516.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25972..26871)
                     /gene="rsgA"
                     /locus_tag="OUE31_000483"
     CDS             complement(25972..26871)
                     /gene="rsgA"
                     /locus_tag="OUE31_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HCU0221517.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27036..29105)
                     /gene="pknB"
                     /locus_tag="OUE31_000484"
     CDS             complement(27036..29105)
                     /gene="pknB"
                     /locus_tag="OUE31_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HCU0221518.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29102..29842)
                     /locus_tag="OUE31_000485"
     CDS             complement(29102..29842)
                     /locus_tag="OUE31_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HCU0221519.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29855..31213)
                     /gene="rsmB"
                     /locus_tag="OUE31_000486"
     CDS             complement(29855..31213)
                     /gene="rsmB"
                     /locus_tag="OUE31_000486"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HCU0221520.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31213..32151)
                     /locus_tag="OUE31_000487"
     CDS             complement(31213..32151)
                     /locus_tag="OUE31_000487"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HCU0221521.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32144..32635)
                     /gene="def"
                     /locus_tag="OUE31_000488"
     CDS             complement(32144..32635)
                     /gene="def"
                     /locus_tag="OUE31_000488"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCU0221522.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32650..35058)
                     /gene="priA"
                     /locus_tag="OUE31_000489"
     CDS             complement(32650..35058)
                     /gene="priA"
                     /locus_tag="OUE31_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HCU0221523.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35311..35616)
                     /locus_tag="OUE31_000490"
     CDS             complement(35311..35616)
                     /locus_tag="OUE31_000490"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCU0221524.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35621..36235)
                     /gene="gmk"
                     /locus_tag="OUE31_000491"
     CDS             complement(35621..36235)
                     /gene="gmk"
                     /locus_tag="OUE31_000491"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HCU0221525.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36722..37006)
                     /locus_tag="OUE31_000492"
     CDS             complement(36722..37006)
                     /locus_tag="OUE31_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221526.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37024..37914)
                     /locus_tag="OUE31_000493"
     CDS             complement(37024..37914)
                     /locus_tag="OUE31_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HCU0221527.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(37934..38152)
                     /locus_tag="OUE31_000494"
     CDS             complement(37934..38152)
                     /locus_tag="OUE31_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HCU0221528.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38122..39822)
                     /locus_tag="OUE31_000495"
     CDS             complement(38122..39822)
                     /locus_tag="OUE31_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HCU0221529.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40088..40861
                     /locus_tag="OUE31_000496"
     CDS             40088..40861
                     /locus_tag="OUE31_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221530.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(40942..41511)
                     /gene="thiT"
                     /locus_tag="OUE31_000497"
     CDS             complement(40942..41511)
                     /gene="thiT"
                     /locus_tag="OUE31_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HCU0221531.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNSWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(41577..41679)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(41685..42656)
                     /locus_tag="OUE31_000498"
     CDS             complement(41685..42656)
                     /locus_tag="OUE31_000498"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCU0221532.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(42750..44123)
                     /gene="glmU"
                     /locus_tag="OUE31_000499"
     CDS             complement(42750..44123)
                     /gene="glmU"
                     /locus_tag="OUE31_000499"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HCU0221533.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(44626..45444)
                     /gene="purR"
                     /locus_tag="OUE31_000500"
     CDS             complement(44626..45444)
                     /gene="purR"
                     /locus_tag="OUE31_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HCU0221534.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(45611..46435)
                     /locus_tag="OUE31_000501"
     CDS             complement(45611..46435)
                     /locus_tag="OUE31_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCU0221535.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46408..47088)
                     /locus_tag="OUE31_000502"
     CDS             complement(46408..47088)
                     /locus_tag="OUE31_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCU0221536.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47111..48049)
                     /locus_tag="OUE31_000503"
     CDS             complement(47111..48049)
                     /locus_tag="OUE31_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HCU0221537.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48294..49157)
                     /locus_tag="OUE31_000504"
     CDS             complement(48294..49157)
                     /locus_tag="OUE31_000504"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HCU0221538.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(49299..51872)
                     /gene="mprF"
                     /locus_tag="OUE31_000505"
     CDS             complement(49299..51872)
                     /gene="mprF"
                     /locus_tag="OUE31_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCU0221539.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52013..52819
                     /gene="proC"
                     /locus_tag="OUE31_000506"
     CDS             52013..52819
                     /gene="proC"
                     /locus_tag="OUE31_000506"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HCU0221540.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(52898..54454)
                     /gene="rny"
                     /locus_tag="OUE31_000507"
     CDS             complement(52898..54454)
                     /gene="rny"
                     /locus_tag="OUE31_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HCU0221541.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(54865..55914)
                     /gene="recA"
                     /locus_tag="OUE31_000508"
     CDS             complement(54865..55914)
                     /gene="recA"
                     /locus_tag="OUE31_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HCU0221542.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56023..57264)
                     /locus_tag="OUE31_000509"
     CDS             complement(56023..57264)
                     /locus_tag="OUE31_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HCU0221543.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGAVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(57504..58082)
                     /gene="pgsA"
                     /locus_tag="OUE31_000510"
     CDS             complement(57504..58082)
                     /gene="pgsA"
                     /locus_tag="OUE31_000510"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HCU0221544.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58291..59214)
                     /locus_tag="OUE31_000511"
     CDS             complement(58291..59214)
                     /locus_tag="OUE31_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0221545.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(59953..61239)
                     /locus_tag="OUE31_000512"
     CDS             complement(59953..61239)
                     /locus_tag="OUE31_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCU0221546.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61232..62500)
                     /locus_tag="OUE31_000513"
     CDS             complement(61232..62500)
                     /locus_tag="OUE31_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCU0221547.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            62752..63213
                     /gene="mscL"
                     /locus_tag="OUE31_000514"
     CDS             62752..63213
                     /gene="mscL"
                     /locus_tag="OUE31_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HCU0221548.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63272..63718)
                     /locus_tag="OUE31_000515"
     CDS             complement(63272..63718)
                     /locus_tag="OUE31_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0221549.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(63811..64056)
                     /locus_tag="OUE31_000516"
     CDS             complement(63811..64056)
                     /locus_tag="OUE31_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HCU0221550.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64171..64749)
                     /locus_tag="OUE31_000517"
     CDS             complement(64171..64749)
                     /locus_tag="OUE31_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCU0221551.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(64826..65356)
                     /locus_tag="OUE31_000518"
     CDS             complement(64826..65356)
                     /locus_tag="OUE31_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HCU0221552.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65360..66220)
                     /gene="rlmB"
                     /locus_tag="OUE31_000519"
     CDS             complement(65360..66220)
                     /gene="rlmB"
                     /locus_tag="OUE31_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HCU0221553.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66213..66608)
                     /locus_tag="OUE31_000520"
     CDS             complement(66213..66608)
                     /locus_tag="OUE31_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HCU0221554.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(66605..68017)
                     /locus_tag="OUE31_000521"
     CDS             complement(66605..68017)
                     /locus_tag="OUE31_000521"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HCU0221555.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68014..68550)
                     /gene="cysE"
                     /locus_tag="OUE31_000522"
     CDS             complement(68014..68550)
                     /gene="cysE"
                     /locus_tag="OUE31_000522"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HCU0221556.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(68636..68875)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(68872..70332)
                     /locus_tag="OUE31_000523"
     CDS             complement(68872..70332)
                     /locus_tag="OUE31_000523"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HCU0221557.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(70502..71659)
                     /locus_tag="OUE31_000524"
     CDS             complement(70502..71659)
                     /locus_tag="OUE31_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HCU0221558.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(71693..73063)
                     /gene="radA"
                     /locus_tag="OUE31_000525"
     CDS             complement(71693..73063)
                     /gene="radA"
                     /locus_tag="OUE31_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HCU0221559.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73126..73653)
                     /locus_tag="OUE31_000526"
     CDS             complement(73126..73653)
                     /locus_tag="OUE31_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HCU0221560.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT        20129 a        16072 c        13215 g        24247 t
ORIGIN      
        1 ttccttagac agcttttatt cgattatctc attgttggga atagcaaaac atcccgaatt
       61 gattgtgcat cagttagcaa cattactaat ctgtcgatcc cgatgcctag accaccagtt
      121 ggcggcatac cgtattctaa ggcttccaag aagtcttcgt ctacaccgtg agcttcgtca
      181 tttcctagtt cacgttcttt ttcttgcgct tcgaatcttt ctctttgatc aattggatcg
      241 ttcagttctg taaaggcatt agcaaattcg cgccccacta tgaatagttc gaatcgatct
      301 gtgaatcgag gatcttctgg atttttcttc gctaaaggcg aaacttcgac tggatgtccg
      361 tatacaaacg tcggttgtgt caatgtttct tcaacaaatg tttcaaagaa ttcattgata
      421 acatgtccga cacccatagc ttcggttact tctacattgt gtttttcggc taaagctaat
      481 gcttcttcca atgtcatttc ttgccagaag tctacaccag tttgttcttt gattgcatct
      541 accatatgga tgcgtttaaa gtcactttct aagtcgacag cttgtccatc atatgtgatt
      601 tttgctgttc ctagtacttt ttcagctgcg ttacggataa taccttctgt cagattcatt
      661 acatcattga aatcagtata tgctgtgtat gcttctaaca tcgtaaattc tggattatgt
      721 gtagtatcaa ttccttcatt acggaaaacg cggccgattt cataaacttt ttccattccg
      781 ccaacaatta gtcgttttaa atgaagttct agcgcaatac gcaaatataa atcaatgtcc
      841 agtgcattat gatgcgtgat aaatgggcgt gcggcagctc cacctgcctc attgtgcaat
      901 actggtgttt ctacttcaat atagccattg ccatctaaat agcgacggat ttcgctgata
      961 atttggcttc gtttcataaa tcggtcaaag ctttcgcgat tactgattaa atccaagtag
     1021 cgttgtctgt agcgttgttc aatattcgtt aagccatggt atttatctgg cagtggacga
     1081 agtgcttttg acaaaatcgt gatttctgaa gctttgatag aaacttcgcc tgtgtctgtt
     1141 ttcatgattt gtccagttac accaaagaaa tctccaaggt ctgcatgttt gaatacttca
     1201 taggcctcat cacctacttg gtcttttctt acataaattt gaatttggcc ttcacgatct
     1261 tgtagatgcg caaatccagt tttccctttt cctcggcgag tcatcatacg accagctaca
     1321 ctagcggtca atcccatttc tgctagttct tcttttgttc ttggatcaaa tagttcatgc
     1381 aattcttctg agttgtgcgt gcgttcaaat cgttttccaa atggatcgat tccatcttca
     1441 cgcaattgtt ccattttttg acgacgtaca agcatttgat catttaaatc ttctacttga
     1501 tgttgttgtt cctgtgtcac aaaagttcct ccattctcat gttaatctct ttcctataat
     1561 gccaatgaaa cacaaaaaaa gcaagccgaa cttggaattt cggcttgaaa attcacgaaa
     1621 aacttagaaa tcacaacgtt tgtttcaata gtactttttc cgctttttct acaaattgat
     1681 ccagcaggtc attgatttct tgctgttttt ctgtctgatt gattgctact ttcactttcg
     1741 ctgctcgagg aatccctttt aaataataag ccgcatgtgt tctgaattct ctacaagcta
     1801 ctttttctcc tttgagatct gctaagcgtt gtaaatgaag tttagctgta gcaatttttt
     1861 cggctggtgt tggttcagga atcagttctc ctgtttcgag ataatgctgt gtgcggtgaa
     1921 tcatccatgg attgcccagc gctgcacgac caatcatcac accgtctgca ccgacatagt
     1981 caagcatcca ttttgcatct tctggcgttt tgacatcccc gttccccata aatgggatcg
     2041 tcaaatgttt tttcacttct ttcaatactt cccagtccgc ttttccttca tacatctgaa
     2101 cccgtgtacg tccatgcata gcgatggcac ttgctccagc tgattgtgct gctaatgcat
     2161 tttctacagc aaagacgtgc tcttcatccc aaccaatacg catcttgatt gttactggga
     2221 tatttactgc tgaagaaaca gcttggacca tttcgtatac tttctcagga tctaaaagcc
     2281 attttgctcc tgcttctgct ttgattactt tatttactgg acagcccata ttgatatcta
     2341 ttatatcggc agctgtgttt tcttcgacaa attgagcagc ttcaactaga ctatctttat
     2401 ttccgccaaa tatctgtaaa cttaatggat gttctgtttc ttcaatgtgg agcatctcta
     2461 aagttttttt gtttctgaaa tgaatacctt ggtcactgat catttcacat acgactaagc
     2521 ccgcaccaaa ttctttgaca gtgactcgaa atgctgaatt tgttattcca gccatcggtg
     2581 caacaacgac acgattaggg atttccacat tgccaatttt ccatgtgtgt tccacttaaa
     2641 tccctcctaa ggcttctttc ttcaatccat ctaattcttc ttcgctatac ttgtatttgt
     2701 tattacagaa agaacaaacc gcttctgcac cgtgatcttc gtctatcatt gcttggattt
     2761 cttctgcacc taacgcgata attgcttctg caaatttttc ttttgaacag tcacatttga
     2821 attgaacagg cattttttcc aaaatgttca attcttctgt accaagcaat cctttcaata
     2881 tttcttctgg tgtctgtcct tcatctaaga gggtagagat tcttggtgtc gtttttaatt
     2941 gttcttcgat cttgctgatt gtttcttcat cggcacctgg catgatttgg atcatgaatc
     3001 ctcccgccgt cttgatgctg tcgtcagtat tgaccaatac actcagtcca acagctgaag
     3061 ggatttgttc tgagatagca agatagtaag taaaatcttc agcgatttct ccagaaacaa
     3121 tcggcgtttg cccagaaaaa ggttctttta atcctaagtc ttttgtgaca gtaaacattc
     3181 cttgtgttcc aactgctccc cgcacatcga ttttaccttc actatttaga ggaagactga
     3241 gatgcggatt tttgatgtaa cctttcacat ctccctttcc atttgcatct actacaattc
     3301 ctgttgctgg accatcgcct tggattcgaa cagttagttt gtcttctcct ttgagcgtcg
     3361 caccaagtag cagactaccg accaatgtcc gtcccaaagc agctgaggag gtgtgccaag
     3421 tatcatgacg tctttgtgcc tccgctacgg tatttgttgc ttgaacggcg tatgctcgga
     3481 cgaatccgtc gtgagcaagt gccttaacca aataatcttt catttgttat gtactccttt
     3541 ttccgttttt aaactcatag tgaatcatac tagcaactac tgcttttttc aactttggaa
     3601 tgcttctttt aaaaataatt cagaatcatc tagaaaacag gacatcaccc tatttacaac
     3661 ttaaataaag aaatctcccg aaaaccggtt tttgttccgg ttttcgggag tcatatcaga
     3721 tcaattgacc tatatttttt tatttgtatt gatcgtctga atgattatct tctgattgtt
     3781 gagaatctga atcatgttct gctttatttt cctcattcag ttcatgtttt gcttcttcaa
     3841 aatcacgttt ttcttccgct tgtttttcag cgtctttttc ttccaaagca cgttttgctt
     3901 cttcaaaagt tttcgcttct ttttcgcttg gataatcatt tgactcagta ccttcaggca
     3961 tcacaccgtg ttcaaacaat gacttgattg ctttggcatc caatgtttcg aattccaaaa
     4021 gtttttcagc aatcagttta tgctgtgcac gatgagcttc gatgatttct cgagctttat
     4081 catgagcttc catcaagatt tttcgtactt cttgatcaat ctcgaaagcg acttgttccg
     4141 agtaagcttt tgtttgacca tagtcgcggc caacaaacac ttgatggttt ccttcatatt
     4201 gaacaggacc taaacgatca ctcattccat attctgttac catgcttcgt gctagagctg
     4261 tcgcttgctc aaagtcattg gaagcaccag ttgattggac attgaagatg atttcttcag
     4321 ctgtacgtcc accaagtaag cctacgattt gttcaaacat atcttctttc gtcatcaaga
     4381 actgatcttc ttttggtaaa gcgatcatat atccgccggc gcgtccgcga gggatgatcg
     4441 ttactttgtg gacgacccga gcgcgactca atactaatcc gacaatcgta tgaccagctt
     4501 cgtgataagc aaccatttcg cgttcttttt tgctgattac gcgatctttt ttagctggac
     4561 ctgcaatcac gcgatcttcc gcttcatcga tatcagaagc atcgattttc tttttatttc
     4621 ttctagcagc tactaacgct gcttcattca agacattttc taaatctgct ccggcaaaac
     4681 ctggtgtctg ttgagccaca actttcaagt caacgtcatc tgccatcggt ttattccgtg
     4741 catggactcg caagattgct tcacgacctt ttacatctgg acgtccaact aaaatctggc
     4801 ggtcaaaacg gcctggacgt agtaacgctg ggtctagtac atcagaacgg ttggttgcag
     4861 caatgacgat tactccttca tttccgtcga agccatccat ttctacaagc aattggttca
     4921 atgtttgttc gcgttcatca tgtccgccgc ccataccggc accacgttga cgacctaccg
     4981 catcaatttc atcaatgaaa atgatagctg gtgcgttttt cttcgctgtt tcaaacaaat
     5041 cacgaacacg acttgctcca acaccgacaa acatttctac gaaatcagaa cccgagatcg
     5101 agtaaaacgg tactccagct tctccggcaa cagcttttgc taataaggtt ttacctgttc
     5161 ctggaggtcc ttctaaaagt acacctgccg ggatacgggc acctaattca acaaatcggc
     5221 ggggatcttt cagaaattca acaacttcaa ctagttcttg tttttcttct tccgcacccg
     5281 ctacatcaga aaaacgtacg cgattagctt ttttgtctgc ttctttggct tttgatttac
     5341 caaagttcat gacacggccg ccaccgccac cgccgccgcc ttgttgtccc atcatcatgt
     5401 aaaagaaaaa gatgatgatt acgattggca agaagctaag caatagggaa acccatatac
     5461 cgctgcttga ttcttctttt actgttgtag caactttgtt ttcttttgcc agttctgtta
     5521 cttggctcaa tgttgtatca tttggcaaaa tgattgttgt gaaatgggta gtagtcgtat
     5581 ctgttgaacc taagatagct aacccaccgc tgttagcgac ggtctgctgt tctttgtatt
     5641 caccagtgat cttatataca ccatttgcag gctgcacttc aaattctttg atcttgcctg
     5701 cttgtagttg ttctgtgaat tttgagtact cgatatctga cgatcgctgg ccgttattac
     5761 caaaaatgaa ataaacgacc attaccatcg ctaagattac gaggacataa tacaaggcat
     5821 ttttcatcat gccgttgttc tttttgttca tagttgccct ccctaagcgt caatttaatt
     5881 taacagtttt ttatcaatcc tgaccattct attgtaccat aatttaattg agatacagca
     5941 ttaatttgat tgataaacac taggtttcaa tacaccgatg tacggaaggt tacgatatgc
     6001 ttctgcataa tccaagccat aaccgaccac aaattcattt ggtacgttga agccaacata
     6061 atctgcttcg atatttacta ctcttccttc aggtttgtca agtagtgtaa caattttgac
     6121 tgattttgct ttgcggtatt tgaaaagatc cactaaataa gcaagtgttc ttccgctgtc
     6181 aatgatatct tcaacgatca acagatcgcg accttctaca ttcgtatcta agtctttgac
     6241 gatttttact tcccctgacg agactgttgc attcccgtag cttgaaacat ccatgaaatc
     6301 caattccaaa tacgtatcga tagaacgaac gatatctgcc atgaatggta ccgctccttt
     6361 taagacacct actactaggg gattggtgtt ttggtaaatt tctgttaact ctttgcctag
     6421 ttctttgcaa cgaacttgta tctcttcttg tgagatcaaa attctctcaa tatccttttc
     6481 caacatcagg ttctccttcc aattgcttct ttttgatatt tgtaaagaag tatgtagtgt
     6541 attttatcag tttcttcacg aatactcaaa tatgaaaagg caaaaggtat caagctatat
     6601 atatttcttt tggcatctgt aatgatccaa gcatgctgcc tttgtgaatt aggtactttc
     6661 tgatcgataa aatatctaga tacttttttt gtgagattct ctgttaattt aatgcggtct
     6721 cctgcttttc ttttttcgac atacagttgc acatcagcag gaatccaaat gtcatgagaa
     6781 aatagagacc atgaatctgt tgctttgatg tcccctgcat tttcaggttt gaccagacca
     6841 atccattctg tttcattcaa atatattcct tgttctggaa tcagcaacaa gcgctggtct
     6901 tctgtctggc tagttgcttg tttttctttt ttagagagta caacaaaatg atactctctt
     6961 ttcagtatcc aattattgcc aatactgagt tgccattggc tttttttctg ttgccactgg
     7021 tctaaaatcg actccatttg ttgttctttc aaaataattc ctgtttttga gaatgctttg
     7081 tcgaaaaagg agtaaaaaaa atagtatcgt tcagcatctg tcatttcttc aatcatttct
     7141 gcagaaaatc gaaattgttc ctcccactgt tcgacttcct tttcgatcaa ctgtcccata
     7201 tatttttgaa tgacttggtc tgcccattgg atctgttgcg aaaattgctg gaaatgtctc
     7261 aacgcctgtg tattttcttg tttcaattga ggaactacca aatgacgaag ccgatttctc
     7321 tggatatcta acaattggtt tgtctgatcc tcaaagtaaa caagctgcga ttccgctgca
     7381 taagtatata ggtcttcttt gctaaaactc agcaacggac gaatcagtct gcccgtagca
     7441 aatggttgta cttctttgat tccagaaaaa gtatttaact gtcccccacg aacgattttc
     7501 attaacaccg tctcgatttg atcatctccg tgatgagcag tcatcaacgt gtcatattgt
     7561 ccttcttcca tcacgcgagt gaattcttga taacgaaagt tacgagcttc tgtttctatg
     7621 gcggatttgg ctggatcttc ccaaatactt acatataaag ggagattctt ctcttcacaa
     7681 tatgagcgaa gataggcagc ttcttctgct gattcttctc ttaattggtg attgatgtgg
     7741 acgataccta aagaaaaacc gatttggcgt tgcacttgta aaagtaaatg gagcaaaacc
     7801 atcgaatcaa caccacctga taccgctgct aaaattctcg atccttgttg ccagaatcct
     7861 tgttcattcc cgtgccgaat aaatgactgc tgtaatagcg gtgctttttt cccgcctttt
     7921 tcaacgttca tcctttccac accctttctt cctaaaaaaa agagagcggg aaaacgtcta
     7981 aaacgacaat taacctgccc tctgttgata ctatgaccca aatagtcgca ctatcattat
     8041 ttgcggcttt ttagctgcga cgtccgccac ggccaccgcg ctttccttct gtgtttcgct
     8101 tcaatgaaga taagcggtca tcgctatctt tcaaaaatga actcatcaat gaatcgaagt
     8161 cttctttttg agctgaaggt tgactgcgag aaaaagattt tttctgtgct ggacgatttc
     8221 ggttgtcacg gggatctttt tgttgatatt ttttaggacg gctttcttct ccagattcag
     8281 caggttgttc ctgcgctttc cggatagata gtccgatttt tccatcatca tttactgaaa
     8341 taactttaac tgttacttca tctcctacac ttaaaacatc atggatgtct tttacatagc
     8401 catttgacac ttcgctaata tgaactagac ccgtttttcc agcacctaga tcaataaacg
     8461 caccaaaatt tgtgattcct gatacttttc cttgcagttt tgctcctacc tcgattgaca
     8521 taaaaaaaat gttcctccta attatttccc ttttttatat tcctgcttat tttgcagttg
     8581 tagaactagt tgattgatct gtttcatttg tcgagctgtc tgtatttgat tctaatatag
     8641 gataaacttt ttcaccgtct tttgagtaaa agaatttgct tctggcaagt ttagctacat
     8701 actcatcatc tttcagcaat gaaacatctt ggtgcagctg atcaacgtct gcgttgactt
     8761 ctttcatttc agtatttgct tcgactctca attcgttcaa ttgatgcatc ctttgcatgt
     8821 catggaaaat ctgcacacct attatcgcga aaatgaccaa agcaccaaca aaaattgcag
     8881 ccagtctgcg tcttcgaaaa atcagttgac gttgttgttg ctgaaattca gcatactttt
     8941 tctttgcata ttccgtatct agcgcagcga ttttattgct ttttttcgtc acttggattc
     9001 gctccaatct ttttgattgt ctttttcatt ataccaatat cgtgaaagct tgtctaatct
     9061 atttctctag tgtttctgtg cgattttcag aaataatttc gtacattttt tgtgcatctt
     9121 cttttttggt tgattcatgt aattccgtaa ttttcacttc caacgttttg ttgccaaact
     9181 ggactttcaa aatatcgcct actttgacat cactggaaga tttcgccaat ttaccgttga
     9241 tttgaattct tcctttatca gctacttctt ttgctactga tcgtcttttg atgattcggg
     9301 aaatttttaa aaatttatct aatcgcatat cttattcctc actttttaat ttttttattt
     9361 aatcgcagga ttttcttacc aaaaggcaac attagccatt ctcgtactgt aaacagacga
     9421 agacgaatca ctgcataaat gaacacagaa gccccgatcc caactcctat cacgctgaca
     9481 aaaaaagcag tggaacgatg agttacagga ccaaatacta tattcaatac accataatac
     9541 agcagcagta ctactgtcat acaaagaagg ctgaacatca acttccgtcc aaaatgccgt
     9601 tctttccaaa aagcatttag ctcttttgtt tcaattcgaa caaaatacca aagcgtcaca
     9661 cctaatccta aaagggtaga caggcttgca cctgctgttc ctaataaacc ggtcagaaaa
     9721 gaagtagtca atccttttac caatagtccc catcctgcgc cttttaaaga agggcgaaac
     9781 gagttcttgc tttgagcaat actttgataa gcttggatga ctgcagtgaa agcaatggaa
     9841 aaaacaaata atacaagcgc tgcatttccc gcataatctt taaacaacgc ataattgata
     9901 taagggagca gcaaggctaa tcccaaagac gcagctaatg ctaaagcggt cgtcaatcta
     9961 agatagattt tggctgtctg taaaaactga cgatagatcc ggttggtcaa atgacgagtc
    10021 aacgcaggca ggaatgtcgc acttaatgca gtggcaatca ctaaacctaa ttgtactaaa
    10081 ggctgacctc gatcatagac cccttttgct atcttcgcac cgtattctga cagtccgtaa
    10141 acttccaaag cattttttac aaagaaagag tcgatcagct ggaaaaagat aagcaatcca
    10201 ctataaatcg aaaccagtcc gccttctacc agaaaacgcc ggatcaaggg ctttgacggc
    10261 tgtttgaaca atggaaaccg tcggaagctt aacgctcctc catgaatctt ttgttcatag
    10321 tagtgaagga tcccatatgc gcataaaccg ccaaaaacag ctccactcat tgctgccgtc
    10381 cctgtttggt acaccgtcca tccaagcttt ctaaaagcaa acgcactaca gacaatcaca
    10441 aaaacacgaa cgaactgctc aactacttga gaaacagcag ttggttccat caagaatctt
    10501 ccttggaaat tccctcgata aaaagataga ccaggcatca gcaaaaaggt aaaggaaact
    10561 acttggatca gcggtttcaa ttgtatgtct cccatcatcc aagcaatcca gctgctaaat
    10621 gcaaagacaa acaaccacaa aaagacacct gtccaaaata ctaagggata aagattttgc
    10681 aaagcttgct ttcgctcgaa aggattcttt ctttctgcaa cgtactttga tatgaactgc
    10741 ggaagaccgg ataaagctaa agtcattgct atcccataaa ttggataaac ttgctgataa
    10801 acataaaaac cttcgtcgcc gactaagttt tggaggggaa ttcggtaaag ggcacttaat
    10861 acttttgcta tgaaagaagc aatcgtcaat acaaatgctc cttgcatgac gcgccgcatt
    10921 tctttatgat ccaaatcatt gctccttcct acgctgacag atatttttgc tcacgcaacg
    10981 ctttgacaaa cttttggatt tcctgaagcc atactgcttc ttccatttgg ttggggatcg
    11041 tcaagcgtat caccatctgt tctttttcaa cgcctagact ggcttttagt tttgtcgctg
    11101 tcagtgcttc gaataactgt tccacactat agcgttttgt tccaacttta cttagagtaa
    11161 agactatatg cgcctcctgt ttccttatcg tttctaggag cgctcgatcg ccatccattt
    11221 tgatctgccc aattgtcaag agatgtgcta cttcttctgg atattctcca aaacggtcga
    11281 gcagatcatc ttctagttca tctagcattt cttgcgaatc aagttcacga attcgtttat
    11341 agatctcgat tttctgccgt tgatctgcca cgtatgtttc aggtagatac gcatcgacac
    11401 cgaggtcgat ctcaacagtg gtcttctcca cttgactatt ctttccttgt ttacgagaaa
    11461 cagcttcgct tagcatttga gaatacatat cgaaaccgac tgcatcaata aatccatgct
    11521 gctgagcacc taagagatta cctgcaccgc gaatggaaag atcccgcatc gcaatcttga
    11581 atccagatcc cagttctgta aaatctttga ttgcctgaag acgtttttca ctgacttcgt
    11641 taaggatctt ctgctgctca tacataaagt aagcatatgc gacacggctg cttcttccta
    11701 cccgccctcg caattggtat aacgtggata atcccatata atcagcgttc tcaacgaaca
    11761 acgtatttgc gttcgggata tctactcctg tttcaatgat ggttgtagtg acaagaacat
    11821 catattgacc ttcaataaat tcaaaaagcg tattttctaa ttgcgcctct gtcatttgcc
    11881 catgagcata accgatccgt gcttccggaa cgagttcttg gatttcttct actttttgtt
    11941 cgatcgtttc tacccgatta tataaataga atacttgtcc acctcgtccc atttctcgat
    12001 ggattgcttc gcgaatagcc ccaggatttt tttccataac atacgtttgg atcggataac
    12061 gattcgcagg cggtgtttcg attactgaaa gatcccgcac gcctaacatc gacatatgca
    12121 aagttctcgg aatcggtgtt gcagtcagag tcaaaacatc cacttgtgca cgtaactgtt
    12181 tcaatcgttc cttatgtttt acaccaaaac gttgttcttc gtcaatgatc agtagaccca
    12241 aatcgctaaa ttcaatatct tttgacaaaa ttcggtgggt tcctacaaca atatcaactt
    12301 gacctgtacg cagttgttcg atggtttctt tttgttgctt tcttgttctg aaacgactta
    12361 atagcccgat atttacgggg aaaccttcaa atctttccag catcgtttca tagtgctgct
    12421 gtgccaagat cgttgttgga actaaaaagg ctacttgttt gctttccttt atcgctttaa
    12481 aggccgctcg aagcgctact tctgttttcc cataaccaac atcacctacg agtagtcgat
    12541 ccattggttt ttctttttcc atatcccgtt tgatctccgc tgcacttctc aactggtcat
    12601 cagtttcaga gtaggggaag gcattttcga attctttttg gtaggcgtca tcaggtccaa
    12661 aagcatatcc tttttctgac tctcttgcgg catataattt gattagatcg tcagcgatat
    12721 cctcgatttt tgaagagact tttcgcttgg ttttcgtcca ttcacttccg cctagcttat
    12781 tgatgcgagg cgctttggct tcagaggcga catatttttg gatcagattc agttgagtaa
    12841 caggaataaa cagtttgtcg tcgttttgat acaaaatagt catatagtct tggtgaacgc
    12901 catctacttc tagcgtttcc atcccaatgt atttcccgat accatgattg gcatggacaa
    12961 cgtaatctcc tgcttttaac tcattatagc ttttcaatcg ctctgcgttt gttactgttt
    13021 gacgtctcgt ttgttttttc gtcgtttttt ggaaaatttc tttttctgtg atagctacta
    13081 ttttttcttg aggaagttca aaaccagcct gcaaagctcc ttcaactaat tgtacctgtc
    13141 ctctgatcaa tgcatttttt tctgtttcta ctactaatat gtcttcatct cgaagcattt
    13201 gttctgcttt gcgtattctg tcctttgtcg gaataaagat cacaacagtc tgtttttgct
    13261 tgcgccaacg gtccatttct gttttcagca atggcatttg tccgaagaac tgttgcatcg
    13321 tccgatattg aaaattatgg attgcttgga aacgaagatt tcccatccct ttttggaaga
    13381 gtgagaaaaa ggttgtggtg aacttttcct tctgcacgat tttttgtata tctgctgaaa
    13441 atgtctgctc agaaaacacc cgcaattcgc tgattttttg agtctgccat tctgccgctt
    13501 ccctttcgat ttcccgattt gtttccatga ttcgctgata atcatcaacg actagtaaac
    13561 tatttgaagg gaaataatcc aagatcgtca cagattcttg gtaaagaaga tctgagtaga
    13621 attttgcttc ttctgtcggg acacctgctt gccagcttga agtcagctga ccgaagtaat
    13681 cttgcaaaaa ctcgcggtct gcttcttctg tggtcgcagc aagccgtttt tctagcattt
    13741 tttgcatttg ctctattcca tgttctagat cctctggtcc gtagacttgt tcactcgttg
    13801 gggaaaccca gatttcttcc gttttttcga ttgagcgttg tgtttctgct tcaaaatacc
    13861 gcatagaatc tatctctaca tcaaatagtt ctacacgaac aggataggtt gtcgttaacg
    13921 ggtaaatatc gataatgctt cctcgaatac tgaattctcc cggttttgcg accatctctt
    13981 ctcgtacata gcccatcaaa gtcaattggc gaggaagatt ttccacgtct atctcatcac
    14041 caatatgcca attcaattgc gcctgtagcc aagttttctt attcggcagt cgtttgtgca
    14101 aagatgcgac tggcaacaaa tagatacctg cttttttttc ttgaagtgcg ttaagcgttg
    14161 caactctctc gcctcgcgct tctggagaag aaaaggccat ttcagcagaa agcacttcat
    14221 ccactggaaa taaatggatc tgatcttgcg gaatcacatg ttgcagatct tctgctaact
    14281 gattcgcata atacaaattt ggcatcagaa taatcatgtt tttatttgtt ttcttaaacg
    14341 ctcgagcaaa tagaagtgtt ttcgctgagc ccgctaatcc tgtgattagt tgtctaggca
    14401 ttttttcttc taaattgctg acccattctt ttacttgcgg atcttttccg actaattgaa
    14461 taatatccat tccttttcct ccttcctcaa ttgaatcgat tcatcgcatc cacgaacgaa
    14521 tgcccttcta tgagatattc gactgcttta acagattgac acatgctttc ttctatcaaa
    14581 ggctgatttt ctttgctgaa aggactaagc acatgctgga ctactgtttt tttcccttct
    14641 ggcctgccga ttcccacctt gattcgatca aagacattcg tattcaaatg ggaaataata
    14701 cttttgatac cgttatgccc gccggcactt cccttttgac ggagccggat ttttcccact
    14761 gccagatcca aatcatcgta gattacgact aattcctctg gataaatccc aaaataagtc
    14821 attagtgggc cgactgcacg accagattca ttcatgaatg tttgtggttt gactaaaagg
    14881 atcttttctc cattatgaaa aaattcggca acttctgctt cgaacggatt ttttttgaaa
    14941 gtagcttgat gctcgcgtgc aattttatcc acgaccataa agccgatatt gtgttttgta
    15001 tattggtatt tggtacctgg gtttcctaac ccgacgatca ttttcatttt tgttttccac
    15061 ctaattctaa aaagcagcac aaaaggctgg actgctaatt agcggtccag tccatcgagc
    15121 ttttttcttt tttatacttg tcaatgcata gtataacaca aaacaaggcg tttcggctaa
    15181 aagagaatcg ttaataaatg ataaataaat taaaaatttc ttcaaagttt aatgaaataa
    15241 ttgatatata aaaatagtga aataacgcac atgtaagctt ttacatataa tacaaccttg
    15301 ttatctgtta tattttatag ccaaatagcg tgacatgggg cttgagaaat gttagcataa
    15361 gcatgggaaa aaacaaatca atggaaggat tgatactaaa tgactgcagc tgcagaaaaa
    15421 aaagatcatc aaaaagttat tcttgttgga gacggcgccg taggttctag ctatgccttt
    15481 gctctagtta ctcaaaatat cgctcaagaa gtaggtattg tggatatcaa tactgctaaa
    15541 actgaaggag acgcaattga cttgtctcac gctttggcat ttacttcacc taaaaaaatc
    15601 tattctgcta cttacgcaga cgcacatgat gctgacttag ttgttattac agctggcgca
    15661 ccacaaaaac caggtgaaac tcgtttagac ttagtaaaca aaaacctaaa aatcaaccgc
    15721 gatgttgtca cacaaatcgt tgaatcagga tttaacggta tctttttagt tgccgctaac
    15781 ccagtagata ttttgactta ctcaacttgg aaattctcag gtttccctaa agaacgcgta
    15841 atcggttcag gtacctctct tgactcagct cgtttccgtc aagcacttgc ggaattagtt
    15901 gacgttgatg cacgtaacgt ccatgcttac atcttaggtg aacacggaga ttcagaattc
    15961 ccagtttggt cacatgcaaa tgttgccggc ttgcaaatct atgaatgggt aaaaaacaac
    16021 ccagaaatcg atgaagaagc tatggttaac ctattctttg gcgtacgtga cgctgcttac
    16081 acaattatcg agaaaaaagg cgctactttc tatggtatcg cagtagcatt agcacgtatc
    16141 actcgtgcca tcttagatga tgaaaatgct gttcttcctt tatcagtatt catgaatggc
    16201 gaatatggat tgaacgacat ctacattggt gcacctgctg ttatcaaccg tcaaggtatc
    16261 caaaaagtaa tcgaaattcc tttaagtgac agcgagcaag accgtatggc tgcttctgct
    16321 aagcaattaa aagaaattct agatgaagct tttgctaaac tagacgctga ataatctttg
    16381 aacatgacgg aaaacatcta ttcggtgttt tccgtttttt tattttatca cccttatggt
    16441 ttctaaattt tttcataaag tagagataac cttcgtcttt tcctctaaat tatgctatca
    16501 tgagaccgtt ccaccctaaa cttttactta aggagttgtc gatatgacaa gatcttcgca
    16561 tcgaaaaaaa tcgaaacatg ttgctttgct ttcagttctt ggtgttctct tagtgctgat
    16621 cagcttttat acctatcgca gtacatacta cacaaagcat tttttgccga atacagaaat
    16681 aaatggaata aatgtcagca atctaacagt cgaaaaagca aatgaaaaat taaaagaagc
    16741 ttattctgat aaaaaactgg ctattaaaga agatggaaaa gtctggcagg aagtaccaaa
    16801 atccgagctc ggctacaaag atgatttcac ttcggagctt tctccgatcc taaatgaaca
    16861 aaacggatgg acttggggaa tgacttatgt ctcagcggca gaaaaacaag aaatagatcc
    16921 tgtcagtcaa aaccaccaaa aactagacac taccgttcag acattgacaa ctaagctgac
    16981 tgatttgaac aaagaccgga cacctactac tgatgcaacg atcgaaaaag caggtgactc
    17041 tttcgttatc aagcctgaag tcaatggaaa tacgatcgac gtcgatgctg cggtcaaaca
    17101 attaaaaagt gcggtaaact ctggtaaaga tacaattgaa ttgactgaat tcaaagaaaa
    17161 accaaaagta acatctgaag acagctcact gaaagaacaa ctcgcatcca tgaatgctat
    17221 cgcaaatgta aaagctactt acagtataaa cggtgagact ttccagatcc catcaagtga
    17281 tattatgagt tggctgacct acaatgatgg aaaagtcgat ttagatacag aacaagtacg
    17341 tcaatatgta acagatttag gcacaaagta taacacaagt acgaatgaca caaaatttaa
    17401 aagtacaaaa agaggagaag ttacggtccc agttggcact tacagttgga cgatccaaac
    17461 agacagtgag acagaagcat tgaaaaaagc gattctggca ggccaagatt ttactcgttc
    17521 acccattgtg caaggtggca caaccgctga tcatccattg atcgaagata cgtatatcga
    17581 agttgatctg gagaaccagc atatgtggta ttacaaagac ggaaaagtgg cccttgaaac
    17641 agatatcgtt tccggaaagc caactacacc tacacctgct ggagtcttct atgtttggaa
    17701 taaagaagaa gatgcaactt taaaaggaac aaatgacgat ggaacacctt acgagagtcc
    17761 ggtaaactac tggatgccga ttgactggac aggtgttggt atccacgatt cagactggca
    17821 acctgaatac ggtggagact tatggaaaac ccgcggttca cacggctgca tcaacacccc
    17881 accaagtgta atgaaggaat tattcgggat ggtcgaaaaa ggaacgcctg tattggtctt
    17941 ctaacaaaaa taatatataa aaagaaagca cccgtacgat tggtacaggt gctttctttt
    18001 tattatctaa caatgtgcta cttacatttc agcagcagta aagacttctg aaacatcatc
    18061 atcgtcttct agcttatcta ctagacgttc caattgctct ttttgttcct catttaaatc
    18121 aatcgtcgtt tgtggaatca tcgtcaattc tgcttgcgcc aaagtgaact ctttttccaa
    18181 ctcatctcgt acagcagcaa aatcttctgg tgcagtataa atctcgaata cttcaggaga
    18241 agtttgcaga tcttctgccc ccgcctctaa tacatcctca aacatcgtct cttcatcaac
    18301 agtcaaccca tcgcgttcaa tagcgatata tcctttgcgg tcaaacaagt aactgactga
    18361 acccgtttct cccagtgatc caccgtttcg agtaaaagct actcggacat ttgtcgctgt
    18421 ccgattacgg ttatctgtca atgcatggac taagattcct actccacccg gaccatatcc
    18481 ttcatacgtg atttcatcgt aattcgtttc atctacggca ctcgtagcct ttttaatcgc
    18541 ccgttccaca ttgtcgttag gcatatttgc agcttttgct ttgtccacaa caagccgcaa
    18601 agctggattc atagatggat caggaccgcc tgctttagct gccatataaa tttcacgaga
    18661 aagtttctga aagactttcc ctcgttttgc atcttgggca ttttttcttc cttggatatt
    18721 atgccattta ctatgtcctg acatgatttt tcctcccttg ttcttttgag aatacacttc
    18781 tattctagta ctatttcaca aaaaaacaaa gccacagcca atctataaac gcttcttgaa
    18841 tgccgcaaaa agcacacata atatcacagc agtcagagca ccgatcgaat ccaacatgac
    18901 atcttggaac ataggtgttc gtccaccggt catcatctga tggaattcgt ccaaacctgc
    18961 gtaccctgtt gctgaaagcc aagcaaggat cgctgtcagc caccaaattt ttagcttggg
    19021 gaaaacacct aaaaacaagc tgcctcccaa aataaaatag gtaccgaaat gtgcgccctt
    19081 ccttaaaaag aactctaaaa atttggcgta gcccagatgg tcgatactca ccatacttcc
    19141 accataatta aaacgtatac ccgctaatgt gtctttaaat ggctgattag gcagccagct
    19201 ttctaatcgc gaaacttgtg attgctgtcc gtaagtttga gaagaactgt aaaataagat
    19261 tataacgact atcagtgcga ttactaaata aatatttccg tttttcattt gtttttttga
    19321 agaattcata agtcacctct gtattttatc ttagactttt tttgaagaaa caacaatcat
    19381 tttcatagag acttcttcca taaaaaagtg ctatacttaa ttttgtatta caatatgaag
    19441 ggagtttttt catgagttat tcattaaatt ggaatctaga ttctattttt tccggaggca
    19501 gtcattctga tgctttgaac caacggatga agcaattgga agaccaaatg aacgagtatt
    19561 atcaccgcgt aacaaaatgg tcacctagtt ctgacaatgc agagcagtta aacgctattc
    19621 ttcaattgca agaaacgatt acgaatggtt ttacccaatg cagcagctat attactgcat
    19681 tgctttctgc caatgtcaat gattcagatg caaaggtctt atcaggcaag ctttacgcaa
    19741 tgctgcctcg tctgcaatca gccgaaactg tattgtcaaa gaaatttgca gaaatatctg
    19801 acaatgattg gaatcagatg ctttctcaat cttcgtttga aacaattgct tttcgtttaa
    19861 acgagattcg tcgtgatggc tcacaattat tatcagaagc tgaagaaaac attataaata
    19921 cgctttcttt agatggtcta aatgcttgga gcagtcatta tgatacgatt gtagccagca
    19981 tttcgattcc cttcgaacaa gatggacaag tagtcgaatt atctgctgga caagccttca
    20041 ataagatgat gggcgatcca gatccaaaag tcagagaaac acttttcgca gcatgggaag
    20101 aagcctggaa agaaaaggca cccctcttca cggatacttt gaatcattta gatggtttta
    20161 gactttctga ctatgaactt catggtgtca cagattttct acaaaaacca ttagagtaca
    20221 atcggttgaa gaaagaaaca ttgtctgtca tgtgggatac aatccagaaa aacaaacaac
    20281 cccttgttaa ttacttgact agaaaagcta atcttttcgg taaagaaaaa atggaatggc
    20341 aagatcaaga tgcacctatt attttaggcg atttgaaaga aaaaaccttt agttttgacg
    20401 aagcagcagc atttattatc gaaaacttta acaaattcag tccaaaaatg gctaaatttg
    20461 cccaatctgc ttttgaaaag agctggatcg aagcagaaga tcgtcctggg aaacgtcctg
    20521 gtggttattg tactgagtta ccagaaacaa aagaatcaag gatctttatg acctacagta
    20581 attctgttaa tgaggttgcg acacttgctc atgaactagg acatgctttc catagcagca
    20641 cgatgtggga tttaccttct ttaaatcgcg aatatgccat gaatgtcgca gaaacagcaa
    20701 gtacattcgc agaactgatc gtagccgatg ctacattaaa agtcgcaaaa acaaaagaag
    20761 aaaaaatcaa tttgctagat acaaaactgc aaaatgcttt agctatgttc atgaatatcc
    20821 attcccgatt catttttgaa aatcgattct atgaagcacg gcaagaagga ttagtctcag
    20881 aagataagat cacagagatg atggttgagg cgcaaaaaga aggctatcaa ggagctttag
    20941 ctacttacca tccatatttc tgggctgcaa aattgcattt ctttattgat gacgtaccgt
    21001 tttataactt cccatacaca tttggctacc tctttagttt gggcatctat gcttacgcca
    21061 accaaaaggg agcaaatttt gaagaagaat atatccattt actacgcgat actgcctcaa
    21121 tgacgacgga agatcttgcg aagaaacatt tgaatgtcga tcttacccaa ccagattttt
    21181 ggcaagcagg tatcgacatg gtgactgaag atatccaaac gttcatggaa ttgacagaag
    21241 aatttatctg atttctattt tatcacaata aaaaaagagt tagtccagaa tgggctaact
    21301 ctttttgatt aatcattctt acatgctgac agcaaagtca ggggcaaacc attgaactga
    21361 accaactttt acgctttcgc ctggttgagg agcatggata tattgtcctc cgcctaaagc
    21421 aatcgctacg tggtaagttc cgccttgtga cccccagaat aacaagtctc cagcttttgc
    21481 ttgagaaact gaaatttttg ttccagctga ttcttgagga actgtccaac caccgatgtc
    21541 acgaccagtt acttgcatgt aaacatagcg tgtgaaccct gagcagtcaa agccacttgg
    21601 atctttaccg ccccaaacat atggagtacc aatatatttg taagcttctg ctacgattgc
    21661 tgcaccattc acacttccag aaggagctgg agcaggtgtt acaggttttg gttgttcagg
    21721 tgttggtgtt ggcgttggag ccggagtact acttcctgtg ccgtttcctg tatcaacact
    21781 ttgatctgtt gatggtgttg taggcgcagg tgttgttgat tcttctgttg ttgaagattc
    21841 aggcactgtt gttgattctt ctgttgctga agattcaggc actgttgttg attcttctgt
    21901 tgctgaagat tcaggcgctg ttgttgattc ttctgttgct gaagattcag gcgctgttga
    21961 ttcttctgtt gaagattcag gtgttgttga ttcttctgtt gctgaagatt gtgtagctga
    22021 tgatgattct tcagtcattg aagattgtgt agctgatgat tcttctgttg ctgagctttg
    22081 tgcagtagat gaagcttgag tagcttgtgc ttcagcctct gcttgttcgc gtgcttcttt
    22141 ttcagctttt tcttgtgcag cttgttgacg agcttgttct gctagacgtt gttgttcacg
    22201 aatacgagct tgctctgctt cagcttctgc tttttgacgg ttcaagtcag ctttcttgtc
    22261 ttcagcagtt gcttgttcag cagctaatga agttttcagt acgttcaaat cagcttgttt
    22321 agataaaaga tcgccttttt gagattccaa agcagcttgg ttttcagcta attcttttag
    22381 tttagcatcg ttttcagctt ttttgtcttc tacagctttt ttatcttgtt tttgttgttc
    22441 catcaagtcg ttgtttgctt ttaccatcgt tgtcattgct tgaacgcgtc caatagcatc
    22501 tgctaatgaa tcagcattca atacagcatc gatgtagttt gagcttgtgt tgcttacttg
    22561 tgcttcgcgt gcttgttttt ggattgtatc ttcacgtttt tcaatacgtt cttgtaaatc
    22621 tgcaatgtct tttactaatt gtgcagattc ttgacgcaat gtatcttgtt ttgctaatag
    22681 gtcttgtgct tgtgtgttga tttcagaaac ttggctttct aaggcatcga tttgtgattg
    22741 tgcatctgct tgttgatttt tcaagtctgc aatcttttga tcttgctgtt gtatctgaga
    22801 atcaaaatcg tccgccgcgg cagcgatcgg tgatgctacg gcagtcaagg tcattgaaca
    22861 taccattact gctgatatta aactcttttt cactcttcat tcctccgact ggcttaattt
    22921 aataaatatc taaatatatt taagtctttc ttaacgatat aaaaattgta ccatagcagt
    22981 gtgtcaacga tataacagtt atgttacaaa aatgtttcaa aacaactttt aaaaatgaca
    23041 aaactgttcg tttcagaaaa tgatcatgaa aaagccgcgt taagtctagc atttcttaag
    23101 ataacaacga ttctttttcg ctttcgacct aaaaataaaa aaagaaatta ttcatcactg
    23161 aataatttct taaagggaaa aatgaataat acaaatataa tcatgttcaa cagcagtgta
    23221 ggtcctaaaa accttgtaat aaaatacgtg ttatttacta ctgctaattt aaaaatcaac
    23281 tggaccacca tcgtaaacaa ttcataaccc gtgacaaaga tgatcatact gaaaaattca
    23341 gtaaagatgt tgacatggat aacgtctttc attacataca tcaaccatac aattaaaggg
    23401 agagctactg catagatacc gataacgcca atatagtaag cgtcatagat agccccgaga
    23461 acaatcgtgg taatcagtaa ataacgtttt tcaaacgcca tactgcaaca taataatgcc
    23521 aatatcagaa agtgggcatt tgacatatag gtgcctttcg accactcccc tagcattctt
    23581 gttaaatgac catctatcaa catcaaaaag aacaaaacga ttggcagata gtacttcatt
    23641 gtttctttct tcaacatgga ctaatcctcc gctagccgtt ggacaatcgt cacaactgac
    23701 acgtcataca tttctgcata aggtttcaca taaacttccc gatccagccc ataactatct
    23761 ggtttcgttt taataaccgt accgatcggc aagttagctg gagaattccc tccaagaccg
    23821 gatgtctgga caacatcccc ttctttgata tccgtatcac cagttaattg ggtcaccact
    23881 aaggcatgga gcttttcatc atagttttta agcaaaccaa acgcttcgcc attagccgaa
    23941 gatacccgta ctggaaaatg attggagctt tcattagagg atgacagtaa ttcgatttta
    24001 gacgaagccg tattgacctc gatcactcgg ccaatcaatc ctttttgcga catgactgcc
    24061 atatttgctt cgataccgtc tttagaaccc ttgtctacga tcagcatgtc ctgccaactg
    24121 tcaggcgaac gagtaatgac atttgccgtt actttttcgt aactagtcag cgtctgattc
    24181 aactcaagtt cttttttcaa cgcttcgatt tctctctcgt aattcttgtt ttgctgtgaa
    24241 acgtcatcat agctatcgat tttttctttt agccgctcat tttcggcata agttgaaaaa
    24301 agattatgga cagaagctac tccatttcgt acccaccgta ctggggcaga gattgtttta
    24361 tcaaccattg caacactgtc attaacgatg gattggaaga aattgggctt tccttcattc
    24421 gctcgctgcg cagcggtcac acttagtatc gtcaccacga tgataacaat aaccaaggta
    24481 ataataatat ttttattagg attgaacttc ttcacaaaga cacctcgaat taattagact
    24541 cttgtgttca attttatcac taaatgccgt gaaacaaaag gtaagttgct cctcttaagc
    24601 ttttttttag caaataatag attctgtcat ttttagcctg aaagacaaat ttttttattt
    24661 gtttatggat caatctttgc tttgaataac tgcaatcata ccatctgaaa aagaaaattc
    24721 tgcggtatct gaaagaaatt cgttacttgc ataagatgtc ggatattcta cttctttatt
    24781 ttccaataca tacttgctgc cttttaatgt aagattcgag acgggagtca agcagcaata
    24841 agctaaatac ttcatatctg gtatctgtct tactatatgc tctccaggca aataataaga
    24901 caaataattt tgacaatctc tgataataag ctgatgggca aagggtttga agcgaggttc
    24961 catacctaac cagagattgg ctaaaagatg atccaatctt ccgcccgtag ctccaatcaa
    25021 agtgacttcc gcttgcgggt aacgttcaaa tgtttttaag atacctaact gtgtatctgt
    25081 atcgtctttt tctgcagggg aacgggtata ctctttggct tttgcaaata cttccttctg
    25141 ctcttcgttc gacaatgaat caaaatcacc cactgccaga tctactgggt agcctgcttg
    25201 aagcaggtac agcgcaccac ggtctatccc gacataggca tcgtatttgg acagcagaga
    25261 ctgcggccag ttttgcggat tacctccagc agctaataaa attttcattt agtctaatgc
    25321 ctcttttaat cgttcgattt gtccgactgg attttcggct ccatagatat atgatcctgc
    25381 aacgaagaca tccgcccctg catctttaca gatttttgct gtttctggaa cgattccgcc
    25441 atctacttcg attgcataag tccaattgtt ctctctacgt agatcagcga gttccgtaat
    25501 tttttctact gtttcttcaa taaagctttg tccgccgaac ccaggattga cagtcatgac
    25561 tagtacttga tcagccaaag gcaaaacatg tttgatcatg gagactggtg ttcctggatt
    25621 gataactact ccagctttaa ctcctaagct ttttgtcatt tgaagtgccc gatgaatatg
    25681 aggagttgct tcgacgtgga cagtaatgat atctgctcca gcttttgcaa atgctggaat
    25741 gtagttttct ggatcaacga tcatcagatg gacgtctaac ggtaatttag taacaggacg
    25801 gattgcctga acaatatttg gccctaatgt gatatttggg acaaattggc catccattac
    25861 atctacgtgg atgtaatctg cgcctccttt ttccactaac tcaatgtctc tttgtaaatt
    25921 ggcaaaatct gcactcaaaa tggatggtgc tatcttcatt cttgtttcct cctattttcg
    25981 tttaccttct ttttttgcat acattggttt tcttttttcg atttcttgta agaattgcaa
    26041 ataattgtcg taacgtgtct gtgcgatacc acctgtttct actctatgtt ttacttcgca
    26101 gccaggttct ttagcatgca tgcactctct aaatttgcaa tggacagaag cttctacaaa
    26161 ttcaggaaat tgtctcggca gttctcctgc ttcaattgtc aaaaagtcaa tcgagctaaa
    26221 tcctggtgta tctgctacta acccgccata gataggaatc agttccacat gacgtgttgt
    26281 atgccgtcct cttccaagtg catcagaaat ctctcctgtt gctaaattca gttccggtga
    26341 tatttgattc agtagcgtcg attttcctgc tccagactga cccataaaga ccgatagccg
    26401 ttctgggaag taacggatca gttctgtcgt atcacccgta tgattgggta caatcaccgg
    26461 atagcctatt ttagtatagg tttgcttgat ctcttcgatt ttttctgggt cgtctgacaa
    26521 gtcggtcttt gtcaaaaaaa taatcggttc gatcgactcg tattccaagg taactagaaa
    26581 gcggtcaagt agattataag aaaatgcagg ctctacgata cttgtgacaa tgattccaag
    26641 atcaacattt gtgactggtg ggcgaactaa ttgatttttt ctcggcaaga tttccagaag
    26701 atagccgtct gtttgatttt cactctcaaa gatcacctga tctccgacaa gcggcgtgat
    26761 tttccgattc cggaaatttc ctcttcctct tgtttgatag gtctctccgt ttgcgtatac
    26821 atagtaaaaa ccgctgattg cttttctgat ttgtcctttg ataagtgcca cctccgtttt
    26881 tgtttatttt accatacgaa gaggaaagta ggtgttattc catgcaaact tctcaaagta
    26941 tatggcttga aaattgatca aaagagatag aaacacaaaa aagagaatgc aacaaatcaa
    27001 tgtcgcattc ccttctgata tattttattc agcacttatt ttgaactttc tgaggtgcta
    27061 gctgatgaac ttgtggagct ggaagattct tcttttgaag agttgcttgt gctactggag
    27121 ctacttgagc tgctagaact gtctgaagag tctttttcag aactagaaga cgctggatct
    27181 ggtcctttag agtaaattac gttcacaacc attcctttgg taattgtcgt tcctgcccct
    27241 ggtactgtac gaatcacttt atctttatcc accgtgtttg aatattcgga agtctcatgc
    27301 ccgatatatt ctgcaccgac actagctaaa taactttgtg cttcgctttt tgtatagccg
    27361 gagatatcat tcaatttagg ctctgttcct tggcttacga caaaattgat gtaagtttct
    27421 tctgctacaa cttcacccga ggctggatcc tgactgatga tcgaacctga tggtacagtg
    27481 tcgctatagt cataagtagc actaatatta ttgatattga atccttgtgt aacaagccaa
    27541 ttacgaacag tttcgtagtt ttctcctaca tgactactca aagtcactgt ttctggtcct
    27601 ttgctgactg tgaaagtaat cgtgtctgtt ttaggatcga cttctgtatc ttctgatgga
    27661 gattgcgaaa tgatcattcc gctttctacc tctgaactga attcctcttc tttttgaatc
    27721 aagtcagcag aaaaccctaa ttctttcaaa cttgcttcgg catcttcata acttttacca
    27781 ctgtaatcat ctaatttgat ttttttcgtg ccgctactaa tatacagagt gacttcgcgt
    27841 ttttgcttga ctgtcgttcc cgctgccggg tctgtcttca ctacattacc ttcttcgatt
    27901 ttgtcatctg caatttcttc tgtttttgtt gctacttcta atttcgcttt tgcgagtgtt
    27961 tctctagcag aagcttcaga aagatcagaa acatcaggaa caacaacttc tcctcgcccg
    28021 ccagaagcaa agaatacagc tgttccgatt cctaaaacag caagaatagc taataggatc
    28081 agccaccatt ttttctgtcc tttcttttta ggatcaggca gaacttcttc ctcctctggt
    28141 aaggtttcgt tttctggctt gtcttttggc agaggcatag atttgaatga atcaggcatt
    28201 ggtgcatctt ccgtaagggg tgtgataact tttgtttcat tatccatcac atgaggctgc
    28261 catttttctt cgtttgcacg agctggtgat aatactgtag aaagatcatc agacatttcc
    28321 tcggctgact tataacggtc tgcaggttct ttagccgttg cccgtaaaat cacgttttcc
    28381 agtgcttgtg gcacatttgg atcaagtgct tttatagatg gaagatcatc ttgaaaatgt
    28441 tttaaagcaa ttgttacagc agattcacca tcaaacggta cgctacccgt caacatctca
    28501 taaaggatga tccctaaagc ataaatatct gactgcttcg ttgccatact tcctctggcc
    28561 tgctcagggg acagataatg aacagatcct agcatcgtat tcgtctgcgt gatcgatgtt
    28621 tcagataaag cgatagcaat cccgaaatcc gtgattttta caacaccttc attatcgatc
    28681 agtacgtttt ggggtttcaa atctcggtgg atgatttgat ggttatgagc taaagaaata
    28741 gcagaaagga tctgctgcat aatatttact gctgtttcat aaggaacagg ataatgtgtt
    28801 tggatatatc gtttcaagtc cattcctttg acgtattcca tcaccagata ctgcatgttg
    28861 tcttcttcac caacatcgta aacactaaca atgtttggat gaacgagttc tgttgctgct
    28921 aaagcttctc tctgaaatcg tcgaatcgca gtctggtcat tttgaaagtc aaatcgtaag
    28981 actttaactg ctacatcacg atccaagatt aaatcgtgcg ccaaaaatac atttgccata
    29041 ccaccgctac cgatatttcc agtgatttga taacggccat ttaatttttt gcccaactcg
    29101 atcatacact gtcctcctta tattcgataa gaagaacggt gatattatcc gctccgcctg
    29161 cttcattggc acgatcaatc agctcagtta ctttatgaga caatgggcct tcttgattga
    29221 tgatcgttcc tatttcttct tcagacagca tgttcgtcaa gccatctgaa cataacagca
    29281 gtcgatcttt tagttgccaa agatgagtag aaacatctac ttcgactgtt ccaggcatgc
    29341 cgacagaacg tgttaaaata tttttccttg gatggttcac tgccatttct tcgctgattt
    29401 ctcctgattt gactagttca ttgactaaag aatgatcctc cgtcaattgc atgattttat
    29461 cttcacgaat caaataagct ctgctatccc caacattggc aatcgtgaac cagtcatctg
    29521 acagagcggc cgctacgatt gttgttccca taccgttata ttccggctgt tcttgtccac
    29581 gctgataaat cagcatattt tcttcttgaa tcgattgaat gaaccattgg gcgatttttt
    29641 catcgtcaac agcttcttgt ttttcccaag cttcgcctag attcgttacc gccatctgac
    29701 tggcaatgtc tccggcacga tgaccaccca tcccgtctgc taatacagca agcttgagac
    29761 ctgaacggct ggtaaataca ctggcatagt cttgatttgt gttacgtcgt cttcctacat
    29821 ctgattgata ttcaatctgc attttttcac ctcattactt tttgcgcaaa caacaaatga
    29881 aaaatccatc tgtgtaaaac tgatgcggat acaaagtcaa cattttctct tcgattgatg
    29941 attgtagcat aggattggtc aaaacatcaa tcctctcaaa atcagggtgt ctttccaaga
    30001 aagcagaaac aacgtcttgg ttttcttctt ttaagatcgt acaagtgcta taagtcagaa
    30061 taccggaaga ctttaaagtt ggtgcgcagc tttctaaaat ttccaattgg atttttggta
    30121 aattcgctaa ttcatccggc tgttttttat aacgaatatc tggttttcgc cgaagcagcc
    30181 caagacctga acaaggcgcg tctactaaaa tccgatcaaa ctgctctgct tcgaactgtt
    30241 tactgacttc tctagcatcc atcttttgag cgtagacagc agaagagaca cctagacgtg
    30301 ctgcattatc ttcaatgagt ttgactttgt gttcgtgtac atctaaagcg accacttctc
    30361 caccgcatga cggatctaaa aaagaagcaa tatgcgtcgt cttacctccg ggtgctgcac
    30421 aggcatctaa gacatgatgt tcaggctcga tttgcataga cggcgctaca agcatcgaac
    30481 tttcatcttg gatcgtcatg acgccatcgt ggaacaatga gctagaagct aaatgccctt
    30541 ttttcgctac tataccgtat ggactgactt ggcttttttc agctgtgatc tcttcttctt
    30601 gcaaaacagt gatggcctga tctctggaaa gtcggcgtgt atctactcgg gcactagcat
    30661 ggctaggctg atatagcgat aaaccgagct tttcagtttc ttcgtatccg atttgatcca
    30721 ccagtcgttt agtcatccat agaggcaggc tgattttgac agaaagtctt tcgataggat
    30781 cagcaatgcc ttgcagatct ggtgctcctt gacgctgata attcctcaag acaccattta
    30841 caaatttccc tgtcccagga tttcctttta cttttgcgat ttcgaccgcc tcgtttaaaa
    30901 tagcatgtgc agggacttta tctaaaaatt ctaattggta tacagaaaga taaagaagcg
    30961 tcttgaccca gtcatccact ttttttgctt tagcgatcaa tggtgcaacg taaaattcca
    31021 atagtcgctg atggctaatc gtaccataga tcaattctgt aaataaaccc acatcttttt
    31081 gatttagctc gctttgtttg atcatctcat tcaacaaaag attcgagtag gcgccaccct
    31141 tgttcactcg ctctaatgtc agtaatgcca tatatcgtac tgattttttc atttttttag
    31201 ggattttttt cattatttca cctgctgacc aatctgaact tgctgaccgc ttccgttaag
    31261 gaaatcatgt acggcctgtt ttcctttacc agctggctgt aattcattga tggctaagac
    31321 ggtctgttta ccgcaagcaa tccatagatt ttttttgtct ttccggatga tcgtaccagg
    31381 tgctttgtct gtagtttctg ccaatacttc aaccgataat aatttccagc gtatgccctc
    31441 ataggtcgtg aatgcaattg gccaaggacg cattccgcgt acttggttgt caatttcttc
    31501 tgcagtttta tgccaatcga ttgcttcttg ttcccgtgtg atgtttggcg aaaaagttgc
    31561 ttctgactcg tcttgaggta ctggtttttg tccatccaaa atattgggca atgtttctag
    31621 caatagcttt cttcctaaaa ggctaagctt ttcaaacatc gtccctacat catcttgttt
    31681 agtgattggt atgctttctt gcgcatagat tccgcctgca tccatttttt tgatcatttc
    31741 catgatcgtt acaccagttt ctttctcccc attcatgatg gcataatgaa caggcgcacc
    31801 tccccgatat ttaggaagta aagaagcatg gacattgatt gcccctaatt ttggtacttg
    31861 caataacttt tcaggcaaga attggccaaa tgccgcagtg acgatcacat caggcaccaa
    31921 ttcaatgatt tcttccattt ctggcgaacc ggagattttc tctggctgca gcacacggat
    31981 accgtgcttc agagccgctt cttttaccgg tgtcggcgta attactcgtt tccgcccaac
    32041 tggacggtcg ggctgtgtta ccactgcctg gatctcgtaa cctgattcta tcagcccttc
    32101 aagaatcggc acagaaaaag caggtgtgcc cataaatact agcttagtca tcaagatgtt
    32161 cctccatata ttcttcaagt tcttcttccg ggatctgctg tatcattttc tcaatgaaca
    32221 agataccgtc taagtgatcg atttcatgct ggaaggcacg ggctaaatag ccaaaagccg
    32281 tcacttctat ctcttctccg tctcgatcat aataacgcac ggtcacttca tctgctcgct
    32341 tgaccgttcc atagacatgc ggaatactga gacaaccttc tacgtcaagg ctttcacctt
    32401 ttgcttcgat gatttctggg ttaatcagtt caaatttctc gccttcatct acttcgatca
    32461 cagcaattct cttgttttgt cctacttgag gagcagcgat ccctattccg tcattcgcaa
    32521 tcattgtctc atataaattg tctaataaag cgattgtctc gtccgtgatt acatcgattg
    32581 gctgagcagt tctttttaat ttatcattag ggtggatcaa tataggatag cgcataattt
    32641 ggccctttct taaataaagt ttaatggttc gttgtcaatt gccacaaaaa gaccttgtcg
    32701 ctgttctttc tggcttccat tcaaaatttc atccaaaaca tgaggaagat tcggttcatg
    32761 tttatatttg atgattagtt gataataata tcggtttttc actctcaaaa tcatgctggg
    32821 cgttggccct aatagcaagc tttgagggct taacacttct tttagctgat tggcaatctg
    32881 aaagattttc tttgccgcta cttgttcttc aggatggctg gcggttattt tcacagtaaa
    32941 gtaataagga ggatagcctc cacgatgccg tacatgcatt tcctgctgat aaaactgctc
    33001 ataattttgt tttttagcca attctatggc gtaatgttga ggattgaatg tttggatcac
    33061 gacttcgcct gctttttccg ctcgccctgc tcgtcctgaa acttgggtaa gcaattggaa
    33121 tgtatgctca ctagaacgaa aatccggtaa attcagggag gtatcagcat tcaacacccc
    33181 aactaatgtc acttctggaa agtccaaacc tttagcaatc atttgtgtcc ctaataatat
    33241 atctgcttct tttgcaccga atttttgtaa aatctgttcg tgtgcccctt ttcttcgagt
    33301 ggtatctaca tccatacgca aaatcctagc ttgcggataa agttctcgga gttcctcttc
    33361 tactttttga gtacctgttc catagtagcg gattttattg ccgccacaat taggacagcg
    33421 attgggaata ggttcttcat gtccgcaata atggcagcgc attgaacgtg tatccatatg
    33481 cagtgtaaga gagatatcgc aattaggaca tggaagaaca aatccacagt ccctacacat
    33541 cacaaaagac gaatatcctc gacgattgag cagtaggaca gtttgttctt ttttgtctaa
    33601 tcgattttgt attttttcct gcaaattagc agaaaaagta gaggtccgat gattctgaaa
    33661 ctcttcacgc atatctacga tctcaatagc tggaagctgt gcagctgctt tggctcggtg
    33721 gtttaactgc aataactgat aaacgccttt ttgagctcgt gctcttgatt ctaaagaggg
    33781 cgtcgcgctt cctagaacta ttgggcaatg atgatattta ctgcgccaaa ttgctagatc
    33841 tctcgcatga taacgcggtg tctcatcttg tttgtaactt gattcatgtt cttcatcgat
    33901 aatgatcagc ccgatatttt tcagcggggc aaaaatagca gatcgtgcgc ctactactac
    33961 ttgcgcttct tcccgctcaa tcttgcgcca ttcatcatat ttttcacctt gggaaagtcc
    34021 gctatgtaag accgcaactg attctccgaa gcgtcctttg aatcgctcga ccatttgcgg
    34081 agtcaatgcg atttcaggca ctaacataat agccgtttta ttttctgaca aaacatcagc
    34141 gattgcctga agatatactt ctgttttccc gctgccagtg attccctcca gcaaaaagac
    34201 ctgatctttt tgctgctgac ctgctgtgat gatttgttcg acagcatttt tttgttctgc
    34261 attcagttcc aatgccgtcg tttggtcaaa tactcggtct ttataagggt cgcgataacg
    34321 ttctgattct ataaactcca gccagccctt ttcttttcct tgattcaaga cagcagtact
    34381 gattccttta tttttgaaat aagcaattgg ttcttcttgg ctcagttcag ataaacacaa
    34441 aagaagttct ttttgtttct tggcattttg ccgtaatttt gcccattctt cttcgatttg
    34501 cttttcagtt aacaaagaac ggaccaaacg aatcgttttt actttatttc gtgtatggac
    34561 ttcatatttg atatctacta attgctcttg gcgccagcga atcaattgag aaaggctgcc
    34621 ttcttcttct gcttccttcc aggaaatcac ttctcgctga tcaaacaata cctgaacttc
    34681 tggtgtgtct gccaaaggat agatcaattt atcatattct gctttcatca cactcggaag
    34741 catcgtttgt agacaagtga ttttgaatgc gtaagtaatt tttttcatat aatcagctaa
    34801 tgaaagtaat tcttcattga ccaccggagc aaggtctagc aaacgaataa ctgccttcaa
    34861 agatggatta gctgattctt ctgatttttg gatagccata acaaatcctt ggacatgacg
    34921 attgccatta ccaaaaggga cttctactcg catcccgact tgcaaagctg tttccatttc
    34981 agagggaacc aaataagtga atggctgatc ggtctgcata gtaggtacgt ccacaatgac
    35041 ttcagctgtt aatgtcatgg ttcgtttcct cctttttttg tcttttctta tcaagcgaca
    35101 aaaagttcct tgcctatttt actagagatc gatggatttg tcttatcttc tgccaaatcc
    35161 taacaaaaaa ttaacagcag ataagaaaaa aaagaactgt gtcaaaaagt tcagacacag
    35221 ccttttctac cagacaataa gtggcgaatg tttgaaaagg aaacagctgg gtttgctttt
    35281 ctttttagat gttcgctcta tttttcttta ttacattttt tgctcttcac ggatacgtga
    35341 ttccaattcg tgttgttcac gctctttttg tgcttgacgt tcctcttctt ccatcttcaa
    35401 acgttcacgt tttaattcag gatgtggatc attgactaca tttcctgcat cgatttcttc
    35461 taaagcttga ccgacgcttt ttactgaatc aaaagaatct agagtaggct gtgcacttgc
    35521 atccaattca tgcgcgcgtt tacttgctaa aatcactaga gaatattttg aatttacacg
    35581 atctaatagt gagtcaattg aaggttttaa catcataaga ctacatctcc tttaacattt
    35641 taatatattt accgattacg cgatctactc gaaaatgttc actggcaata atgtttttga
    35701 ttcgttcaac tgctagcggc acttcatcat ttacaacagc atagtcgtaa agagccatca
    35761 tttcgatttc ttcttttgca actttcattc gttcttcgat tacttcatct gcatctgttc
    35821 ctcggcctac gatccgtgat tttaattccg ctaaatctgg cggagtcaaa aagatgaata
    35881 caccatcggg cactttttct ttgacttgtt ttgctccttg gacttcaatc tccaagaaaa
    35941 catcttttcc ttcatccaat gtcttgttga catatgacaa aggagttcca taataattcc
    36001 cgacatattc tgcgtattcc agcatctctc cagcttcgat cattgattca aactcttctt
    36061 tgcttcggaa gaaataatca acgccttcga cctccccttc acgcatttta cgggtagtca
    36121 ttgagatcga atactgaaaa tcattatcct cactctcaaa aattgctttt cgtactgtgc
    36181 cttttcctac accggatgga ccagacaaca cgattaataa tccacgctct gacatgacga
    36241 cgtcctttca actagtcttt ttgtacttat cgtttatttt gcactttttt tctgcaactt
    36301 tcaaggttat ctttaattat agctagaaat tggtaaaaaa gctaccctgt accaagaggt
    36361 cgtaaaaaag ctgtcctgca tcaagtaata agaacagcca aacataaaca gcttctcatg
    36421 tttttcgttt ggttggggtt attatcgcag atgcaagctt ttgaacgccg tgtataagag
    36481 gtcgtgaaga agccgattag tttcgagtat gaagaaaaat tttgtgaaaa tagtttctca
    36541 catttttgca taaatttggc ttaataccga gaaaatggtt tttgaacatc acttattcaa
    36601 aataaaaaaa gattgtgaca cgaattttgt cacaaccttt aaatgtattc ctagagcaaa
    36661 gaagctaagc gaagaaatcc aattctgatt atttattgta tttctttgtt cagcatcctt
    36721 gctaaaagcc catattggac aaagtattca ctacacccat gatctcatct tttcgagaac
    36781 gtgctttttc tgtcggatct tctacctctt ctgtgtcaat tcgaacaata aatttccgat
    36841 tcatcgtcac gtaagcaccg tcgttgatca aaataaacag ttcgttctca ttatagtctg
    36901 cacaggcatc tttccatacg tcaaagccgt ttttttcaga agggatatcc cgtttaacca
    36961 cagtttttcc acttaattcg tggaacgtta cgtcataata tttcattatc tctacctctt
    37021 tcgtcattca atattttgta cttgttctct gattttttct aagatcgtct tagactggac
    37081 gacttgattt ttaatttcga ttgcatttga tttggaaccg atcgtgttga tttcccgatt
    37141 catttcttgg atcaggaaat ctaattcccg acctacagga cattgtgctt cgataagttc
    37201 atctagtttt tgtacatgga tcgccagacg atccagttcc tcgtgaatat ctccgcgttc
    37261 caacaagatg gctagctccg tcaacaaccg ttgctcatcg actttcgctc caagaaattc
    37321 ctccagcttt ttttgatacc ttatttgaaa ttccttttca tagatttcta caaaactatc
    37381 gagttttttt agtacttctt tgaattcttc agtattcttt ttcaacacta aagctaaagc
    37441 ttgaccttct ttttctcgac tcgcctcaat agaatcaagt gcgcttttca atgtatctag
    37501 agctaactgt gccaattctt ccatgctctc ttccggtttt tcttctaccg ttacgaagtt
    37561 ttcgtccagc gcgaagcgtt ccgccatccg actaattgac acttgatttt gactaccgta
    37621 tcgttgttga attccgtctg tcaattgagt gataagtgaa tcaatcaatt cccagttgat
    37681 gacgatctgt ttttcgtttt tgccaatata agctagattc acaaatactt cgattcgacc
    37741 gcggcttaac tgctgtttaa taagctgacg aaaatcgttt tcaacaaagt tcaggatttt
    37801 aggacttcgt atttgaacat ctagaaaacg ctggttgaca ctttttattt caatatctaa
    37861 ctgatacgct tttgtttcgc ggatggcttt gccaaaacca gtcatacttt tcattcgaca
    37921 gggtccttcc tcattacata ttttctattg ctttttgcag ttgttcaaac tcttcgttcg
    37981 tcaatgtcag gcctttcccc attttttcat ggtctggcgc ccaatctcga agatcgaatt
    38041 ttggcgggcg accattccag ctgactaggt tcagttcttt acgccacccc ttgttgtttt
    38101 ctgacaatat agcgatttct tctacgattt catatgaaaa ttcttgtgcc atggttgttc
    38161 ctccttgaga taatataaat ataggatcag taatgtgtca actggttgct taagcaattc
    38221 atgctgcaaa cgatccttgc gttttccttg tagcagataa tcaaaataaa cagttttcgt
    38281 gcgctcattt tgtatttttt gctggtattt tcgatacctt cgccattctt cagtacttaa
    38341 ttgaccaatt tgtgccaata aatcatccgg catacttttt atatcttgtt ggcagatcat
    38401 ttgaatcatc atgtctactt gatagatttc attgggcagt aaaaaatgtt tttttgctaa
    38461 aagttctagc atcgccaatc cgcatgtctc tggtacgacc ctgttcttat ataaattacg
    38521 cagtttttgc caaaatttta tgcttttgaa aaaagataat tctaactgaa tttcttttgt
    38581 taagtaagac aaaaatcctc gccagtatgt tcttgcaggt ttaacagaat gaaatgtata
    38641 ccagttccca tagtaatagc ctaatcgttt tttcatttcc agatagccta attgtaaatt
    38701 taattggttc ctttggctat caaaaagcag aaagctgcct agtgtccaca atgtttgaca
    38761 tttccaatgg ataaaaatgt ctggcatacg aatttttttc gctgggcctg gcccttgcac
    38821 atctacgaca aatgcctctg ttgctccttt gttaatcgca atatcaatag gtattttgtt
    38881 gcgataccca ccgtctgcat atttattttt tccgatcttt cgataagcca tagcgggata
    38941 aaatgaagca gaggcgagta tccaatctgg tatttcttct gtttttgtct gttggatatc
    39001 agtcactact tccgctagtt ctggcagttt agtagacacc gtatataaac gtattttggg
    39061 attatgtttg agtaaggaca aatccaaatt gtctttgacc atcttttcca atggagcaga
    39121 agaaaccccg ccttcaatta gtgctgtttt cgtcatttgg cgtctttctc gatagaagcg
    39181 ttcacgaagg tcttcaactg cagccatttc tggtaacgca agcacttgtc ttgtcgacag
    39241 ctttttccat aaattcacag cttttttcat atctccttgt aaaatcaatg cgccgttcaa
    39301 cgcacctacc gaggtacctg tgataatctc aaagttgata tcatgttcct tcagcgcctg
    39361 ccacacacca atctgataag caccgtgtgc tcctcctcca cctaaaacaa gtgctgtatg
    39421 atagaccagc tttttattta attgtgtggt tccttgatag ccgtttttat gaaaaatacg
    39481 caaccattct tctgatagag gagattgaaa taaaaaacaa cagttttctt taataaaaaa
    39541 acgagcgcaa gcttccatat accgaaaaaa ttttttccat tcaaaagttt caccttcaat
    39601 caacagatta ttaaaaataa catctcctct acttttagca atagtaaaat agacggtata
    39661 ttttttcgat actgctttaa aagcacattg cttttttgca gaacgccaaa aagcgtctct
    39721 actttcttga tgactttgaa aaaatggaag gggttgtttt gcttgctgga taggcgaata
    39781 cagcgacatt ttctgtgaaa agtaaacttt ttttatctcc atcgcgctct cctttttctt
    39841 caagtatacc agtacgtcat aaaaaggtca tgagtctcgt attcgacttt gtagattcca
    39901 taagaaaaca attcataaaa catcctttaa ataaaaaata caaaaatcac aaaaattaat
    39961 tgaaaatgag agtgttttca atgaaaacgt gattttgtaa tggaatttta aaataaaaga
    40021 aacaagcttt tttaatgcaa atgttgtaaa ataaaagaga ttaagaggaa ataagaggag
    40081 gaacatgatg actgagtcag tttatgtaca tattgatacc acaagtaatg ctgttttaac
    40141 aaaagggctg actgctactg actttgcaaa cagtatcgtg cattttcctc aaaacttgct
    40201 cttgcttgat ccatctgctt ctgctggaga atatgaatcc catacagggc tgaaagtaat
    40261 ccgtggtaca gaaaatattc agcgtttctt ttcctcttct cgtaacaggc gtggattcga
    40321 tgaattgaag tggatcgact ttactgattt aacgatgctg aaagaattga cacctttaga
    40381 aatttcagaa ttattatatt ttggtcatat gaaaacacat cttcattcgc cgttttttta
    40441 taaactacag aataattttg tatacttcga tcttaatgat cagctgaatc ggatttatta
    40501 tcgctattta gatgaatttt ataggatttt tgctagtaaa ttaagttcga tcttgtcaga
    40561 taagatcaat gtaaaaaaat cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt
    40621 ggaattattg aaagaaatgc gtaatttgat gcaggaaggg atcatttttt cttttgatca
    40681 agttggtttg atcgatggta aatatcgtat cccaatctat gtgattgaag attatatttg
    40741 gaaattaaaa ggcacccggt atcgagaaga ggaaatcatc gctactttaa tctactctgt
    40801 caccgatcga cactggcaat tggtagaaga tgccgatctt tcttatctgc cattgaagta
    40861 gatctatttc ttatcaaaaa ataaaaagga aacaagaaac taggacatga ttctgtctca
    40921 agtttcttgc ttctttttta tttacagctc ctgtcgttta tctggcacaa aaatcgaagg
    40981 agtcgtttgt tggatcccta ataaaacgat gatcgttaca atagctgtac tcaacccgct
    41041 ggcaccattc attacgaaag aaaagagcca agaattcatc ccccatagtg catacgctcc
    41101 ccagaaaacc actcctgcaa taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc
    41161 accaaacacg atgctttttc taatttgttt cgtattatcg tctacatagc ctttttggac
    41221 atttgaagcc atgagccctg ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa
    41281 cacttgaacg acacttaaat aataaacttg tcccaacgga aaatgtagga tgccccaaat
    41341 gaaacctgcc agcatccctg cctttgtccc tcttcttaac gcaaaaagag tcaatggaat
    41401 ctgccctaat gaaatagaaa aactgctgcc gatctggatc ggaatcaacg acaacaccat
    41461 cgctaacgct gcaacaatcg ttccttctac ccaaactcta ttttttccca taaaaaaact
    41521 tcctcctttg aataaaaaag tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc
    41581 tgtttattca caattcctac gctcgcataa ccgatacagg tacgaagggt ttagaaatag
    41641 attcaatctc agcccaattg gactcccctt tgtgagttta tttattattt attttttgtt
    41701 tcaaacaatg gactaactgg tttgttttca tggatacgtt tgattgcatc tcccattagt
    41761 ccgccaacac ttacttcatc gattttgtcg attttacgat cttctggaag atagatcgag
    41821 tctgtaacaa ctagacgctc gatagctgaa tcttctattc tttgtaaagc agggccggat
    41881 aatactggat gtgtacatga agcatacaca ctagttgcac cagcttcttt caaagcattg
    41941 gcagccaatg tgatcgtacc tgctgtatcg atcatatcat cgatcagtac acaagttttg
    42001 cctttgactt gtccaatgat attcattact tctgcaacat ttgcttttgg acggcgtttg
    42061 tctatgatcg caatcggaga tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca
    42121 ccatggtctg gtgaaacaac gacaacatca tcgcctttga ttcctttttc taagaaataa
    42181 ttggcaataa gtggcgcacc catcaaatga tcgactggaa tatcaaagaa accttggatt
    42241 tggactgcat gaaggtccaa agtcagcatt cttgttgcac cagctttttg aatcatgttt
    42301 gctactaatt tcgctgtgat tggttcccgt gcacgtgctt tacggtcttg acgcgcatag
    42361 ccataataag gcatgactac gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc
    42421 atgatcagca actccatcaa gttatcattg actgggctgc tcgttgattg aataacatag
    42481 acatgcgatc cacgaatact ttcttcaatg tttacttgaa tttctccatc actaaattga
    42541 gtaacagatg attttcctaa ctcgacgccg actgctgctg caattttctc tgctaatggg
    42601 cgattggaat ttaacgcaaa aatttttaat cttgggtcaa agtaatgttt tgacatgggg
    42661 acctccactt tctttttcac aactctagaa ttctacctaa taaatagtag tcatattttt
    42721 taaataaatc aagtgatttt gcaaaagtct tagtttagat aagggagttt ttttgcatat
    42781 ccttctttat tgacttgtct tgctctcgca attgccagcg catattctgg aatattgtct
    42841 gtaattgttg acccggcagc aatcgaactg tttttagcta cctcgacagg tccgatgata
    42901 ttcgtgctag aaccaataaa gctgtggtcg ccgacagtcg tatgatgttt gttctttcca
    42961 tcatagttga cgaagacaac accacatccg acattgattt cttctcccag cgtagcatca
    43021 ccaacataag tcaagtgacc gactttagtt cctttgccga tttgagcatt tttcacttcc
    43081 acaaagtttc cgatatggac gttttcgcca atttcagctt ttggtcgtaa atgtgcataa
    43141 ggtcccacat ctgcatgttt cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg
    43201 acgtgatcct caatcctact gtctacgatt tttgaatgtg acccgatgac acaatcagaa
    43261 ccaatgactg tatttccttg gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt
    43321 tctacgcctg catcgatgta tgtcgttgct gaatcgacaa agcttacgcc attgaccata
    43381 tgcatctggt taattcgctt tctcatgatc tcatttgctt tagctaacgc gatccgatca
    43441 ttgactccca ttgattcttc aaaatcatcc gtttgataag cagcaactgt atggccttct
    43501 tcttttaaga tttcgatgat atctgttaga tagtattcac cttgagcatt gtttgttcca
    43561 actttgctta acgcatcgaa caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt
    43621 tcttgtacaa gagcttcttc tggtgttgca tctttttgtt ccacgatttt ttctacgatc
    43681 ccaatatggt cacggatgat tcgtccatat cctgttgggt tttctgcttg tgccgtcaag
    43741 atcgttgcac ttgcattttt tccttggtga tattcaaaaa gattgttcag cgtttcagta
    43801 gtcaataatg gtgtatcgcc actgataact aacgttgttc ctttttttcc ttccaagaaa
    43861 gaagcagctt gcaaaacagc atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta
    43921 ctgcgttctc ctagttgtgc tttaacttgt tctgctccgt gtccaacgat cgtaatcact
    43981 tcatctggtt tcgtttcact gacccgatta atgatatgtt ctaccatagg tttaccagaa
    44041 acgggatgta aaactttata taattttgac ttcatgcggg tacctttccc tgccgccaaa
    44101 ataattgcat aacgtgcgtc caactgcgtc actcctaaat atagtttgct gatttcagtt
    44161 tatcccagta tacccatttt ttcaacaaaa caagtgattt tcttttatcc cagcgttttc
    44221 tggataaaaa aatagataga ccataacggg cctatctatt tggtaaccgg tgctctcctg
    44281 ccaactcctc ggtcacaagt cacactactc ataaaacatg aaaagctgtt ttttgaaatc
    44341 gtttcttgtg acttagagtt aaacggtagg cttacaacct cttcattaaa cgtttttcaa
    44401 tcagctgacc ttcggtatta gctcaataaa cggcaaaata tgaggagcaa tttttccgtt
    44461 tattgagcta atactcagga caggacgctg atttcacaac ctctagataa acggtgttca
    44521 aaagccagtt tctcggtatt aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca
    44581 aaatttttct tactactcga aactaagcgg ctttttcaca acctcttatt ctgaaaaata
    44641 atttcctggc acaaccgtaa tatttttcgt ttgagtatct acatctttga cataaagcag
    44701 tgacgtataa tcatcgatgg cgcgatgacc gttgaatttt gattcggcaa atacagtgat
    44761 gccaacaagt tctgattcga attcttcaat caagctcttc attccgttga ctgttccgcc
    44821 gcctttcatg aaatcatcca ctacaaggac acgtgaacca cgtttcaaac ttctcttaga
    44881 cagttccatc ttttcaattc tttcagaaga tccagacaca tagttgacac ttactgttga
    44941 tccttctgtt atttttgagt cccggcgtac aataacgaat ggcgcattca gataatagga
    45001 cacagcttgg gcaataggta cgccttttgt ggctacagtc attacagcat cgattttttc
    45061 accaaggtat ttagaagcaa tgattcttcc aacttgacgc agcagttcag gttctcctaa
    45121 caaatcagag agataaacat atcctcctgg aagcagacgg tcttgttctg atagacgttc
    45181 tgctagagat tcaatatatt ttttcgcctc ttcatatgaa atttcaggga tgaacaatac
    45241 accacctgca gcacccggga ttgtttccaa ggttccatac cctcgttctt taaatgtttt
    45301 cttgatgatt cccaaatctt cactgataga agatttagca gattcataac gttcggcaaa
    45361 gcttgttaag gaaatcaatt catgcgggtg attcaataaa tactgtgtca tgtcaactag
    45421 acgttcactg cgacgtactt tcacctattc caactccttt taagaaattt tatcgtttta
    45481 cattatataa gtttttcttc aaaaattcga gcattttatg aaaaaataag aaaatagttc
    45541 ggtatttatt aaaataaaaa gaagcctata aaaaattttt cgtttttata aggcttcttt
    45601 tctttataat ttagttattt tttcttctga aggcaaccaa tattcgtttg atgatattta
    45661 caatcaggaa caaagcaata aagactaatg tgattgttgc tcctggaggt gtatctagat
    45721 aaaacgagct agttagtcct gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa
    45781 tcacgacatt gaagcttttg cctaatcgca taccgattgc tgcgggaaga accatgattg
    45841 cggatatcaa aagtgcaccg gcaatcggga tcatcacagc aatagccaca ccagtaatca
    45901 cattgaacat catcgacatc aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat
    45961 caaaagtcag aacatacatc ggccgtttga ataaaaagaa caatataccg atggcaacga
    46021 ataagattcc taaaaagatg acttgctccc atgtaatggt cacgatcgaa ccaaacagat
    46081 aggattggat acttgttgct gaattccctc cgctcaaatt catcaatact aacgctagcg
    46141 ccaaaccacc agccattaaa atggcaatgg agatttctga ataggttcgg tagatcgttc
    46201 gcagatactc caatatcaca gctgctaata caacgactag catggtcgta agtgtaggat
    46261 taaggttcaa aaagaatcct aacgctaccc ctgctaaaga gacatgagaa agcgtatcag
    46321 ccatcagcga ttgtcttctg atcactaaaa acacacctag catcggggcg attccggcaa
    46381 tgaagatagc ggcaagaaac gctcttctca tgaattcata tgaaagcaac gccattgaga
    46441 atcctccttt ctcaccagtc ggatctgtct gtccgcatac tgtttgatat cttcatgatc
    46501 atgggtgatc attagaactg atttcccatg gacatgcgca ctatgtcgga gaagacgata
    46561 aaattcattt ctggattctt catccatacc tgttgttggt tcatcaagaa caaataagtc
    46621 agggtcagta gcaaaaatac gcgctaaact gattcgctgc ttttgtccgc cagacaattc
    46681 acctattcgc cgatttcgca tatcccacat ccctacagct tctaaagcac gctgtacatg
    46741 ttgatgatct ttttcagaga gacgcttgaa ccagcggcct cttggatatc ttcctgaacg
    46801 gactaattcg atcaccgtac taggaaaacc tgcattgaaa gatgcaactt gttgaggaat
    46861 ataaccgata cttaattttt ttccttcttg atttttctca gcaatcttta tcattccttt
    46921 tgaaggtttc agtaatccta acgatgcttt caccaaggtt gacttggctg ctccattttc
    46981 tccagttaaa atgacaaatt cacccgcatc tacatgataa gagacatctt ctagtacagg
    47041 ttcatcatca tagtaaaagg tcaaatcaga tatttcgata taacgcacct tacaacctcc
    47101 attctaaaac ttaattgata ctttctttta aagctttcag atttttttcc atgacagaaa
    47161 tataattttc gcctgctttg atttgttcat tagtcaagct ttctaaagga ttcaacactt
    47221 ctagcttcac tcctgtttca ttcgacaatg tctcagctac cttcgaagag gcattttctt
    47281 caaaataaat cactttgatg ttgtttttct tcacaaattc ttttagctca gctaagcgac
    47341 ttggtgtggg ttcctgatct ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt
    47401 gattcgctaa ataagcaaaa gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt
    47461 ttagctcatc ggagtatttt tgatccagtg cttcaagctt tttgatataa gcatcggcat
    47521 tcttcgtaaa agtttccttt ttatctggat atttttcgcc taattcttca gcaatcgttc
    47581 tgacttcttt tatagctaat accggatcga gccaaacatg tggatcgtat tcatgtgaat
    47641 gaccatgccc ttcttctgat tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga
    47701 ttcctttagc tgcttcgatc atcaaggtct gtttgctatc cactgaatcc tttaacgaat
    47761 ccacaaaaaa ttccatgtct gaactattat acacgaaaac atctgcatcg gaaatttctg
    47821 ctctttcttt tgcacttggt tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt
    47881 tcacgtttcc ttcatcccct acgatctctt ttgtaaaatc atacatcgga taaaaagtcg
    47941 taacgatcgt caaatcctct tttttgtctg cttccttgtt cgtatttcca catgctgcaa
    48001 acagtaaagc acctatcatt accgtagctg tcaaaagata ttttttcatt tatatgctcc
    48061 tttcaatgaa caaatcggaa ttttacgatt tattaacgtg aactaatgta tcaaaataaa
    48121 aaaacacagt caatagaaat ccatcaattt ctgatttaag catgtatatt cttgattaaa
    48181 tcgtaaaatg gatgagttgc tgctcatatc tagccatttc actacaataa aaaactgaag
    48241 aataccattt taggattcct cagtttttca tcacctattt tacttcttat attttattgc
    48301 agggttcgta ctaaataaac ttcctcacaa aaacctttta acccattata tactctctgc
    48361 gctcttgaat aatgttgaca caaggcaaaa acggttggtc cgcttccact catcaatgca
    48421 gcatctgctc cgtacttgat catacgctct ttgatttgat ggatgactgg atgccgcttt
    48481 cccgttatat cttctaaact gtttcccatt tttttgatca tctgctgata atcttgctct
    48541 cggatggctt cagcaagtcc gtggatgtct tgatgttgga tggcttgcgt atctacttct
    48601 ctaaacactg tacgtgtaga gacactcatt cttggtttga ccaacacaac ccagcactgt
    48661 ggcatagaag gtaatacttg gatttcttcc cctttgccac cgacaaatgc cgtacttccg
    48721 tagacacagt aaggaacatc tgtaccgact tccaaaccga tttctgccag ttcttctaac
    48781 gaacagccca gattccataa ttggttgatc cctcttagag cagctgcaca gtctgtactt
    48841 cctccgccta atccagctgc tactggaata ttcttcttaa caaagatctt gacaccggtt
    48901 ttgatattgt atttattttt tagcaataaa gcagcttgat aaacattgtt ccgttcatct
    48961 accggtaaaa atgctttatt tgtttctaca atgattttgt cttctgttat ttcttcaaaa
    49021 aatagatgat ctgccaagtc tacgctcgac atcaccattt ccaactcatg atacccatct
    49081 tgccgtctat ataatacatc cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat
    49141 tccatcctct cacccattcg aaaagtctaa gtcgcaagta ttctatcata gggaaaaata
    49201 aaagtatagc ttatgtctgc ctagtggttg attttgtcat cgtttcaaca gctttcacag
    49261 aattttctct tcataatcca aacaagttct agtgattctt ataattctgt gagcacttct
    49321 tctgccaaac tcggaacatt tcctttttct tttcctatca gactgagtag ctgcatggta
    49381 gcaaatccga aattacttcc tttcctataa gcaaaataac gtccttccca atgatcgaca
    49441 tattttaatt tcttttcata agcagactgg aaggaataga aaaaattacc ataattatat
    49501 acgatatgca tgactttttc ttgaaagaaa gaaaaatctg tttctccaac attagctaat
    49561 ggagctaagc ctagattggc ttccgagtag cccattttct cgtatacaat aaacagattg
    49621 gctaacagat agtcagctaa ttcctcagat tctttaggta agacccgcaa caaatcatat
    49681 cccgcctgct tcttcgtcat cggctgagcg gtgatgaagc caacgacttt ttgatcttta
    49741 cggacaatac cgacaccgct agataataca tatgatttat caaatcgtcc cacagagaag
    49801 tatttttctc gtgcaccttg aagccatttt tgtgaaactt catttacagc ttgatgtaat
    49861 tcttccggca gttgatcgta ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat
    49921 tcaagttgct gactcagccg agacaagtct tctgttgcta gatcaacaat ccctgcttca
    49981 cctactttcg tgaagtgaaa acccaattca tgaagcatca ctacgtagct ttctgatatc
    50041 ttataaaacg caagctgata gcctaaacaa tctgcttgtt tcataaactg attcgttgct
    50101 gcccgcatca ttttaggatt gccaactgga tctcctaaaa caaagcattt gtttcctttg
    50161 atctgataac caaaaacgac ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa
    50221 cctgacaagc gaagctgatg gcttgtagct gtgcctccgt atgtttccaa taaacggtca
    50281 aaacggtctt tttcgtactc actgccaagc ttcgtagtat cttcagctaa atattgataa
    50341 agcgccacta aagctagcaa tgagatgccc aaaccaataa gccctgagaa ccacacatca
    50401 tctgaaggaa acaaaataaa atgatttcct gttattcgac cgactaaaaa gcgtccgctg
    50461 tgatagcctg caattgcgta aacgataaac aaaaagccga acaagctagc atcaaagatt
    50521 atagctcccc aagaataaac gaattttgtt cgataaaatt cttttctgga taaccacaca
    50581 gctaacagaa tcaagacata taccaatatc aactgccaag ataacgtacg tgtgattgta
    50641 tttaaaatac caaaagatag taaagcaatc gtaggcagaa atgccttttt gacttttact
    50701 gaaagtgctc tagcaaggcc gagtaataaa aagccaacca atagattcac tgtctgatct
    50761 aaaaaattga atgagaacgg caataatact tgaaatagcc gactgattgc agacagatta
    50821 gtgattgttg atagaagtac catcatgatc cccgcaaaat agacagcact tacgagcacg
    50881 atatgcgcaa ccttttggaa aaacagtcgc ggaatgttat ctaaaaatcg attgattttg
    50941 actcctgtat gtgtgatgaa caatagaagt cccgtcataa aaggtagaac ataataaaac
    51001 aaccgataat ataatagcca aactactgct acatcttgcc gaacagacaa ttgactcatt
    51061 cctaagatca tcaaaacgtc aaaagtcccc attccacctg ggaccatcgt cagcattcct
    51121 atcaatgtag caatcatgaa cataggatag atcgaaagca tcgaaatatc tattctcatc
    51181 aacttgccga tgatcaaaaa taccgcaagg gctcccgtcc attgtccaaa ggatgccagt
    51241 agcagaccaa gcaagccttt tggataaaac tcgaagaaca atgtctttct ctttagataa
    51301 gcaaaaaaga aaatgactgg tgctaaaaaa ctaccgccga aaagccagat ccaatagctt
    51361 cgaaaaatac tttctgactg aataaaaaag acatcaataa atgtaagaaa cgaccataca
    51421 gacaaaccag tcagcataaa tagtgcgact tttgatacag tggctaaaac catttttcta
    51481 tttgtctgct ttccataaaa actagcccgc agacttgctc ctaccacacc accaaaaccg
    51541 gcgagattgt tgatcgtgtt tgttacccac gcagcaagaa gaaactcttt tctttccatt
    51601 tttggttttc cttgtttttc taagactctg atcgtcaccc aatcatacaa caacatcgga
    51661 gtgacaccca gcagtccagc cagaatcatg agcaggatcg tcatgcggct ttgttgtccc
    51721 atcctttgcc aaatatcttg ccaactcatg ccattagcaa tatttgcgac ttgatttgcc
    51781 acaaagacta acacggagcc gaaaaaaatc agttttaaaa tcagactatg ttcctttatc
    51841 cattgcagca tcaagtatcg tttatttttc acattttccc attcctaact tgtatacttt
    51901 tgtgtcatac cccaatgtta tcttatttat tttaattttt ccactttaga cctgttcttt
    51961 gcttgcgatg atagaaaaag aaagatatcc taatgctaaa ggagaggata acatgaaagt
    52021 aggatttatc ggcacaggga atatggcaca agctattatt gatggtttat taaaaaaagg
    52081 aacagtctcg aaagaagagg tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt
    52141 tgctgctgaa actggcgtcc atgcatgcaa aagtaatcag gaagttgcat cacaatcaga
    52201 tatcgttctt ttagccgtga aaccaaaaat cattgaaaaa gtattggaag aactaagaga
    52261 atatagccag aaagtcttat tcatttctat tgcttcagga aaatcattaa cagatttaga
    52321 aacagcgctt gaagatcctc aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag
    52381 cgtaggagca ggcgtttctg cgatttgcaa aaatgaagct gccacggagg aacagcttca
    52441 gcaagctacg atgatttttg aagcaatcgg cagcgtctat cctttagcag aatcagattt
    52501 cagtacattc attggccttg ctggcagctc acccgcattc gtttacatgc tgatcgatgc
    52561 gatgggacgg actggtgtac tgaatggttt gtccaaacag acagccactg agattgctgc
    52621 aaaagcaatt atgggttctt gtcaaaaatt cctttcaagt gataaaaatc catgggaact
    52681 tgtagaccaa gtttcttctc ctggcggtac aactgttgca ggtgtagttg ccttagaaga
    52741 agcaggattc atcccagcaa tcatcaaagg aatcaatacg acgatcgaga aagatcttga
    52801 gatgttgaat aaaaaataat gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc
    52861 tgtggctttt gccgcggctc ttcttttgta ttttttatta tttagcataa tcagttgcac
    52921 gagtttcccg aataacgatt actttgatgt gtccaggata atccagttct tcttcgattc
    52981 gtttacgaat atcacgtact aaacgaacag cgtctaaatc cgagatttct tctggcttga
    53041 ccattacccg aacttcgcgt ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc
    53101 tgttcgaaat attttccaga cttcttaaac gacggatgta gttttctaat gattcacttc
    53161 gcgcaccagg tcttgctgct gagagcgcat ctgctgcagc tacaaggaca gagataacag
    53221 aagtagcttc cacatctcca tgatgagaag cgatcgcgtt gattactact gggttttctt
    53281 tgtacttggc agctaattcc gcaccgatct caacgtgaga tccttcaatc tcatggtcaa
    53341 gtgctttccc aatatcatgg agcaacccgg cacgttttgc taattggata tcttcgccaa
    53401 gctctgctgc taagatacca gctaattttg caacctcgac cgaatgcttc aagacgtttt
    53461 gtccataact agttctgaat cgcagacgtc cgatgatctt gattagatct ggatgaagtg
    53521 tatgagcacc gacttcaaac gctgcctctt ccccgtattc gcgaatacgt tcatccattt
    53581 ctttacgaga tttctcgacc atttcttcga tacgcgctgg atggattcgt ccatcttgta
    53641 tcagtttttc caaggtcatc cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa
    53701 caactgcttc cggtgtatca tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc
    53761 gaatattacg accttctcgt ccaatgatac gacctttcat ttcatcattc ggaagggtaa
    53821 cgactgaaac agtcgtttct gaaacttgat ctgctgcgca gcgttgaatc gctaatgata
    53881 ataagttttt cgctttgcga tctgcttctt ctttggcacg ctgttcagat tcttttacca
    53941 ttagagttaa ctcatgattc agctcttctt cagtcgattt catgatgaca tctcgtgcgt
    54001 cctcttttga taaaccagca attttttcta gttctttttg ttgatcttca atcatttttt
    54061 caacgtcttt ttctcgctct tcaattaatt gctgttttga actaagtgct tcttctttac
    54121 tttcaagtga gttctcgcgt ttttctaacg agtcatcttt acgattcagc gtttgttcgc
    54181 gttgaatcaa acgattctct tgagatttta attctaactt actttctctc agctcacttt
    54241 caacttcaga acggtatttc tgattttctt ccttagcttc taacaatgct tcttttttta
    54301 gagtttctgc ttcttttttt gcactatcga tgattccagc agctgatgat tgtgcaccag
    54361 ctatttcttt ctcgtgacgt gactttgcga ccataaaccc taaaccaaga ccgacaatta
    54421 aaccgatgat agcgaggaga atgttgaata ccataaaatc cacctccata ctatcttttt
    54481 catttttatc atctatacag cttctatgat aaattattct aaactcgtca atatgcatct
    54541 tcgcatatat gtgtacaaaa aacatgcaca actttattct aatgtttgta ccccgtagtg
    54601 tcaactttaa ataaacaaag aaacggcttt ctacttattc attaaacgat ggtttttaaa
    54661 ataaatgaca ctagtttcat ataggtaaac ctttaaattg agaaactttt ctattaaatt
    54721 attctttgta gatgaacaga tatttttatt ttatgtaccc actcgtataa ttaaataact
    54781 cacgatttct ttattcaata aaaaaacggc aggtcaagga gagtacctac tcttcagacc
    54841 agccgttttt gtttatcata atttttattc ttctactaaa ggcaattctt cttgtccttt
    54901 ttcatcttct gggacagcga cttcttcacc aataccataa gctgctctaa ctagagcaga
    54961 aacttctgcc atcatttcag gatgattagc catatagatt ttagcgtttt cccgtccttg
    55021 accaatccga tcttctttat aagaatacca agcaccgctt ttatcaacaa tgtctttttc
    55081 tactgccatg tctagaagtt ctccttcttg tgagatccct aaaccataca tgacatctac
    55141 ttcagcgatt ttgaaaggag gtgctacttt gttttttacg actttgatct ttgtacggtt
    55201 accaacaata tctgtacctt gtttcaattg ttctgcacga cgtacttcca aacggatcgt
    55261 tgcgtagaat ttcaatgcgc gtcctccagg agtgatttct ggattcccaa acatcacgcc
    55321 tactttttca cggatttggt tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc
    55381 agagagttta cgcaatgctt gagacatcaa acgtgcttgt aacccgacat gtgagtcacc
    55441 catttcgccg tcgatttctg ctcgtggaac taaagcagca actgaatcga ctactacgat
    55501 atctacagcc ccacttgata ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc
    55561 aggctgtgaa agaagtagtt catcgatatt cacacctaat ttttgtgcat attgcggatc
    55621 taacgcatgc tcagcatcaa tgaaagcggc cgttccgcca tttttttgta cttctgcaat
    55681 agcgtgtagt gcaactgttg ttttacctga actttcaggt ccatatactt cgatgatacg
    55741 tccacggggg taaccgccga cacctaaagc gacatctaac gcaagagagc cacttggaat
    55801 tgtagagatt tgttggtcga ttttttcgcc caatttcata atagagcctt taccatagct
    55861 cttttcaatt tttttcagtg cagcatctaa ggctgcttta cgatcatctg ccaatacgat
    55921 aatcctcctt atatttacaa atcagagcaa catttcatta tccttatcat atctttttta
    55981 gtgaaaaaaa gcaagaaaaa accgaacaaa tattcgcatt tatcattttc ttaaaagctg
    56041 ttttctcaaa agatcaaatc cttgcataac cgcattatat ctgatagcag cacgatctct
    56101 ggcaaagtga tatttttccg aaaccgcgcc gtctttagat gaaatagcga tccatactgt
    56161 tcctgcagat tgaccttcta acgtgtccgg tccagccact ccggtgaaag ctacactgta
    56221 atctgttctt gctatctcac gtgcttgaat ggccatctgc tccacacatt ctttgctgac
    56281 tgttccatat tctgctaata gctccggatc aatctccaga aaaccagctt ttgtttggag
    56341 cgagtaggta acgaatccgc ctggaaatac ttcagataca ccagcaatgt cgcctaatgc
    56401 ggcttggaag gcgccggctg tcaaactttc cgctgctgtt acagtctgct tgttttcttt
    56461 cagtagttcc actacgactt ttgctagcga attatcatcg ccgtatccat aaaaatattc
    56521 ccctactcgt tcttggattt tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac
    56581 atcatttgtt ttcactgtca gtcgtaatgt cacttcattt ggtttggcat atggtgcgat
    56641 cgttggattg atctgtgtct caatcagatc ttttagctca gtgaccagtc gcgattcacc
    56701 aatcccataa aagcgcaaaa ctttagaaat tagtttttct tcagaaggaa aacgttcctc
    56761 tagtaaagga cgtacttgtt ccacaaacat tggtttcaac tcattaggcg gaccgggaag
    56821 aaggatatac gcatgtgtat ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt
    56881 tggtagagga accccgcctt cgataatctg ggactgttgc agattgtttt tggtcatttt
    56941 tcgatgggtt gtttcaaaat atgccaataa ttttttgtat ccttccgtat tttgtatgag
    57001 agacttaccg aggtgagccg cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa
    57061 tccgccacat aagagtatga gttcacttct tgtttcagct agagcaatca actcttctaa
    57121 acgctgctga ttatctccta caactgtttg ataataaact tcgataccta gatcagctag
    57181 ctgttctgac aagaaagtgg cattcgtatt cacgacttgt cctagtaaaa gttctgttcc
    57241 gacagctatt atttctgctt tcattacttc ccgctccctt atatagtata cgctgtattt
    57301 ttatattttt ttatttaaaa agagggcaag gagctgtgac aaaaatcttg tcacagctcc
    57361 ttgttccaaa taaacagtgt tctcctgcca aaacctcggt cataagtcac aatatacata
    57421 aaacatgaaa agctgttttt tgaaattatc ccttgtgact cagagttaga cggcaggctc
    57481 acaacctctc cactaaacga tacttacatt gatcctttga acacaccgct gtttttgatg
    57541 aagtaatcca cacctgaata gatagtaaag atcagacaag cataaagcat gatttgatct
    57601 actggaatac cgatcaggct gaatgggata ttattgataa acagcaagat aatagcaacc
    57661 atttgtgtag ccgtcttgac ttttcccggc caagctgcag ccatgacttc tccatgttcg
    57721 acaagtagta aacgcaagcc tgtgacggct aattcacgac agacaatgat cgctactacc
    57781 caaccagggg cctttccttg gtcaaccaac atgataaaag cagtcataac tagcatttta
    57841 tctgccaacg ggtccgcaaa cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt
    57901 tttccatcta accagtctgt gatactagct aaagcaaaaa taactgcacc tactagctgt
    57961 gtgacagcca gtgtggtgtc tcctacgtta aattgtcccc aatctaaagg taaacctaca
    58021 accaaaatga aaatcgggat catacaaatt ctaagtacag ttaatttatt tggtaaattc
    58081 acactatcga ctcctttctt ccctattcta cgtgactatc agcgaagttt ccaccgatat
    58141 tatttacttt tccaaatgaa tttattcaaa ggagtatttt tattgaaatt gatctttttg
    58201 aattaacgaa gaaggaccgc gacacagatt tgtcacgatc cttctttttt atacctacaa
    58261 gtaaacagat gcgtaaacta atttatacga tcattctgcg tattgaagag taaggttcac
    58321 attttttgga ctctgattgt tttcccctgg attaactggt acggattctc cattcgcttt
    58381 gatcgttgca ttgcttgctg caccaatcgt gatggtcgca tttgttgctg tttccggtaa
    58441 cacggtactc tgtgtttcat ttgctgccag tgtcccttga taaacatagg cattgtctac
    58501 tagcacacct aaccatacac gattgacagc agtaaattca agggttacag gcttggtagc
    58561 gtctgtgata tttactgcga tggcactgcc agaatcttct cctgtagcta ttgccatttt
    58621 cttttcttca cttgattttg ttgttgattc tactgtagaa gactctttgg tctgcgtgct
    58681 ttgctctgag gaagaggact cctcgactga tccttctact ttaagcgaag aagctgtgtc
    58741 tccgattatt ggatcagctt gacgatcttg ccaagtcata tagcccacga caacgacaat
    58801 cgccaaagca accaatccta ataaaatgac aggaagactt gtccaaaagc gacttggatg
    58861 cgattcttcc tgatgcattg cttttctaga agtacttact gtttcaggct gcggacgttc
    58921 agggaccgat cctgtcaatt tgcttttccc atcaaaaaca tcgactaaat ggtctccatc
    58981 ttctcctaca gcttcagcgt attgccgaat aaatgcccgc acgtaaaatt taccaggcaa
    59041 ttggtcaaaa tcatcattgt cgattgcttc caaataacgt ttttgaattt ttgtaatctg
    59101 ctgtaattca tctaaagata tttttttatt caggcgtgct tgccgtaatt tttctccgat
    59161 ggtttcaaaa gccactcgtt catcttctcc agtctgtttg attctccgaa gcatctgctg
    59221 ttgcaacgaa agacgttatg tttgggtgct gtgacaaaag tcatgtcaca gctccttttt
    59281 tccgaataaa cattgttctc ctgccaactc ctcggtcaca agtcacaata tccaataaat
    59341 ataagaagct gttttttgaa cttgttcctt gtgactcgga gttaaacggc aggctcacga
    59401 cctctttctt aaacggtgtt caatcagctg ttcctcggta ttagctcaaa aaccggcaaa
    59461 atataaggag atatttttcc gtatgtttct ctaatactca ggtcaaaacg ctgatttcac
    59521 aacctcttcc ttaaacggtg ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt
    59581 aaaaacatta agaagctgtt tttacttggc tgttcttatt acttgatgca gggcagcttt
    59641 ttcacaacct cttggtacac ggtgttccag aagtagcttc ttcggcaata agccgaaata
    59701 tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa gctgaccact
    59761 tctgtcacaa cctctttgat tacttcgttt gattttattt taatataagt tgattaaaag
    59821 agagcatgat ttgttttatt ttctcactaa tttttccaac acaactaaga ataccataaa
    59881 agctgatttt ggaggaggtt cctactacaa gtctaaaacg aaatttaaga cttttcctca
    59941 taaaatactg gtttattttg gtctcatgta aaactcgctg aaggcctctt cacttataaa
    60001 tgcttcccca gctgccagta cgtctttcat ttggatcgaa tcgatgattt caggaagatc
    60061 aaataaagtt cgatcgccaa ataaactttg cgtaaattga ttggcaatat attcgatcga
    60121 atttaatgat tggaaatatt gtccaagcat tttcttcttc agcaaatcga gatttgtttc
    60181 tgacacttcc ggatcatcag cgaatccaag aatgatttct ttgacttttt ctgctgcttt
    60241 ctctggttcg tccgtatctc cgctgaagtc cgcaaagtga aattcacgat ccaagctgaa
    60301 ttcaaaacca aagctgtcat cgataattcc ttgattgtac atcgctagat agtttcgaga
    60361 agtattgcct aaaatcattt ggaacaacag attgattgct gttttatagc gtaacagttc
    60421 tgttccttct tgcggcaatg tgtctaatcc tttaatacca agtacaaatt tatctcgtgt
    60481 aatggctgct tccaatgcac tttgtttgat gatttctttt gtgttttcag ggaaataacg
    60541 tacaatttct tgctttggag ggaaattttt tgcttcttgg ttttcccgaa taagtttcat
    60601 caatttctca ggctccatct taccaactac aaataaaacc atattgcttg gctgataaaa
    60661 cgtccgatag cacgtataca agtcttgagc tgtgattttg tcgatacttt caaccgtgcc
    60721 cgcaatatcg atatgcaatg ggtgtgtagg atacaagtta tttagtatgc caaaaaacat
    60781 ccgccagtta gggtcgtctt catacatttg gatttcctga ccgatgattc ctttttcctt
    60841 gtttacagtt tcttctgtga agtaaggtgc ttgtacaaaa tcgatcagag tcgtcagatt
    60901 cttttctacc tgatccgtcg tagaaaacag atagctggtt ttcgtaaaac ttgtgaaagc
    60961 attggcggaa gctccttgtt tcccaaataa ttgaaagaca tcaccatctt ctttttcaaa
    61021 caacttatgt tctaaaaaat gggcaattcc atctggaact ttcacctttt ctttttcacc
    61081 atagggaata aattcgttat cgatcgaacc ataattcgta ctgaacaaac catatgtctt
    61141 gtgatagtca tttttaggca acaaatacac ggtcaaaccg tttggcagta cttcatgata
    61201 aagtgtttca ttgatttgct catattctgt tttattcatt tgcatttcct cctgctaaaa
    61261 agaagattgc ctgcaattcg atttgctcag ctacttgttg tatctctttg atcgttacgc
    61321 tctccatacg tttcaaccat tcttcatcag ataattttgt ttccggcagc cagctgtcca
    61381 aaaaagaagc ttcgattgcc gcttgcggag agtctagaga aagcagatat tggtttctca
    61441 gcattgcttt tgtctgagac agttccaact ctgttatttc accatttcgc aaactttcta
    61501 attgctcgtg aatcagatga agtacttgat ttcggttctt ttcatcgata ccggtttgga
    61561 cactcatgaa tcctcggaac gtatccacgc tactagaggc ataataagct agactttctt
    61621 tctctctgac attcatgaaa agtttagagt gaggaaaacc gccaaataaa ccgttaaaga
    61681 ccattagcgc aaaacgttct ggttcatcgt aatacacatt tgtctgataa gctaggttca
    61741 gctttgcttg aacgattggc tcacgtactt gtcgttcctt cacgatattc acttgaggtt
    61801 gggtataaaa cagatctgga taaactgttt cccgcgactc aaatggtaat tgcccaactg
    61861 cttcagctgc tttgtccgga tcaacatcgc cgacaacaaa aatgtcgatt tgatcatttg
    61921 ccatcatttc ttgatagtag gacgctagcg aactagcagt gatcttgtcc aaatcttcga
    61981 ctacgcccaa ccctgggatc ttttgttccg ggctgttttc aaaataaagt tcttgcaagg
    62041 cataggaagc aaaagtttgt ttatcttcct tcaaactttc caaatataga cgcagattgt
    62101 tcttttccaa gtcaaacgtc aactgatcaa actgatgatt tttaatattt ggataaaata
    62161 aaacctcttt taaaaaatct accgcttgag aaaaaaggtt tggatcattg acatattcac
    62221 cattcacaaa actgatccct gcgtttagcc aatgtaaatt tccttttttt ctaactgata
    62281 atccaaagct tgcgccataa agctctgcaa gttgcgcact taactttgtc tgatccggat
    62341 aattcaaact atttgtttcc aacatgctgc tgagaagtga acgtttcgtg atgacttctt
    62401 gttgcagacg cgcagtaaaa cggataaaaa tccggatcgt tttgtattgt tttgttggta
    62461 agacatgaag attcacgcct tctgccaatt gatacaccat atttatatgc tccttttcac
    62521 agttgattgc ccgcttactc ttttaatggg tcaacctgcc ttttttactt attcctctgc
    62581 ttgaaattta taagttcagg caattcgccg ttttttctaa atgatgttac actttatagt
    62641 atagcataga tgttttttat caaaagaaac agacggctaa aagcgtatat tgttttttta
    62701 ttttttattt ttcgatatac taaagacaaa taaaagaagg gagggtcatt catgatcaaa
    62761 gaattcaaag agttcatcat gcgtggagat gtcttggatc ttgctgtcgg cgttgttatt
    62821 ggtagtgcgt ttacaagcat cgtaaaccaa gtggtgcaag gcttgatcac accactaata
    62881 ggttggtttg tcgcaatgat cacaggtact tctgatttag aaggagcact ttcaattctt
    62941 gactggtcgc cgacaaaagg cgtcacattt gcgtttggta acgttattag tgctatcatt
    63001 acatttctga tcactggttt tgtcttattc ttagttgtca aagcggcaaa ccgtgcgaag
    63061 aatttacgct ccaaagaaga gcaagtggaa gtggaagaaa ctcctactgc agaagattat
    63121 cttagtgaca tacgcgatct tcttgccaaa caagtggcag aagacaatac acatccagta
    63181 gagcaaacaa atctttccga tacttctaaa taataaagaa tctaaaaaaa agaaagccga
    63241 ttttcagtgt cggctttctt tttttagatt cttaacttgc tacttgttcc tttttcatgt
    63301 cgatatgtgg aatatcatct tccaaataca catctgagat tgccttgaat ccaaacgact
    63361 cataaaaagc ttgtaggtat tcttgtgcgc cgatcacgat tggtttttct ggaaaatttt
    63421 tctggatcat gttaatcgtt tcttgaacaa tctttcttcc taaaccatct ttacggttgt
    63481 cctgatgaac aaggacacgt ccaaaatgga tactctccgc ttcttcatat actcgcgtgt
    63541 aggcaaggat cttcccatca gtatcttgaa aaaacgtatg ccaagcttgt ccatcaatgt
    63601 catcaacttc ttgataagga cactgttgtt ccacaacaaa aactgcgatt cgttctttga
    63661 cgatcgcgta aaactctgct gttgacaatt cttcaaattt ctttacctga tattccacta
    63721 agcaaacgcc ccctgctttt ttattcttag cataccgatt cgcacacaaa aaagcaaacg
    63781 aaccttacga atctcaggct cgtttgcttt ttaaactgct tcagttaaaa attcgatctc
    63841 aactgtccga gtaagtacat ctgaatagct gtaggatact cgttcaaaag aattttcttc
    63901 aggatccaaa tcaacaacga atactgaagg ataggtttct gttaaaacgc cgcggcgttc
    63961 tgtttgacgc tttcttcctg tctgagcaac caacatgatt gggctgccga tacgaccttc
    64021 taaatctttc ttgattgaag ctaaagttgt tggcatacag ttcacctcta ctatcaacta
    64081 taccacatat ttttaaaatt ttcaagttta ccataaaaaa aaaagaaatg caataaaaat
    64141 aaataagaag ctcattaaga tttttctaaa ttattcctca ttataaaatt tcaagtgttt
    64201 ttttattttg agttttactc tcccgtaagc gctcattact tgcttgtgat ccattgctaa
    64261 acattcagcc atgtctacaa aatcaacgcc ttgcatataa taatgaaaaa ttttagcttc
    64321 tatttttgaa aactggattt cgcaattttc gattgcttct tttaataaaa gatgctgaat
    64381 cgctaaaggt tcttgcaatg tgatctctgc taaaaagtct ggtccttctg tctctatttt
    64441 ttggtcgatt gagacttcat ctttttgatc acgacgcttc agcgcgttct gcttcctcaa
    64501 cagagaatag atttgattgc ttataatgct tttataataa cttccaaagc taacaccttt
    64561 gcttttttcg taagttctca atgcctgata taaagcgatc cttgcttctt gttcccaatc
    64621 ctcagaaaca taatttctta aataataggt gtttttcaaa cgtagtaaaa gtggaaaata
    64681 tttttgatac agggcagcaa atgcttcttc gtcaccatta cgtgcagcgc gcaataactc
    64741 ctcagacata aaataattcc tccataaatt cgtttatgga ggaatcttat catcaatgat
    64801 tcatcgaact gattagaacg atatgttatt tattttttct cattaaatcg tccaattttt
    64861 gggacaattt ttttaactgc tcttcattcc atggagaatt acgtcggaaa tcaataaaat
    64921 gcatatcttt attttcttgg gctattgttt tttccgtttt ttttatcgtc ttatataatt
    64981 cataagcaga agttcgtaat gctccttggg aaaagatcat ccactgttct gctaaatcgc
    65041 ttgtcgccac tgtcacttgt gtcaaacggt cattcagctg accagcgatt ctctcgatat
    65101 aactgtcagc cgtttcgtct tctttcgtaa aaacaacatc caactggtat ttcttataat
    65161 tttgttggat gcccggaact agttgggcat cgaagacaac gatgacttcc attccttcat
    65221 atttcgcata atttgataaa cgatgtaaaa gagcttctct tgcatccgcc attttgtcct
    65281 gctttttaag ctggacaagt tccggccacg aaccaatcat gttgtagccg tctacaatca
    65341 acagctgttt tttcatggtc tactccccct gacgttggga aaaagcctga tacataagca
    65401 aaccagcagc aacactggca tttaagctct ggacgtgccc ggtcatcggg atcgtcagca
    65461 attcatccat ttcttttttc aatcctggac tcattccttt gccttcatta ccaatgacta
    65521 aagcaattga tcctttggca ttccattttt ggaagtttgt gccggtcata tctgtgccaa
    65581 atacccaaaa tcctgtttct ttgagctgtt gcacagcttg taccaaattc gtcacgcgtg
    65641 caacagggac atgttcgact gccccagtgg aagtctttgt tacgataggt gtgattccaa
    65701 ctgctcggtg ttttggtatg atcacaccat cgacgccact tgcgtctgct gtccgtaaaa
    65761 tcgacccaaa attgtgtgga tcttcgatgc tatccaaaat caaaaagaag gggtcttctt
    65821 ttttctcttt tgttcgttca atcagttggt caagggataa atattcataa ggtgtaatcg
    65881 caagaacgac tccttgatgc acgccgtgat cgctcaaagt ttctaatttt tgtttaggaa
    65941 cccatttgac tggcacagct tgttcacgtg cgatttcttt cagttcttct actttttctc
    66001 ctcgtgaatc ttcttgaaga aagagtttat tccctcgccc ttgttgtagc gcttctactg
    66061 cggcatggtg cccaaagacg aaattatctt ctaatgcttc ttcattttga tcagaaactg
    66121 actgatttcg tccagtttgc tttttatttg aatatctatt ttgttttttg tcttcaaatc
    66181 cacgtttcga ttgatgtttg tttgttcttt ctttacccat ttttttcacc aactttctga
    66241 atacaccagc ggatcaattc ttccatccgc tcggtttgtt ttgtcaaatg cagatagccc
    66301 atgagcgctt cgaaccctgt tgcgacccga tacgtcgtaa catcagcatt ttttgcgctc
    66361 gtatggcttt tagcatttct tcctctgcga taataaagtt cttcttcttc tgtcaaaaga
    66421 tgttcttcca gcatttgctg aatcaaaaag gcttgtgcat tcgcagaaac ataattcgtt
    66481 gccgcacgat gcagcttatt gggttttgtt tctccttgat caatcaggtg gtcacgaaca
    66541 tagatttcgt aaatcgcatc tccaacataa gccaaggcta aaccgttcaa ttgtgtgtaa
    66601 tctctcatgc ttctcttctc catcgggttc cttgcggtgt atcttctaat aagatccctt
    66661 tttctttcaa caaatcacga atttcgtcgc ttcggacaaa atcacgattg cttcttgctt
    66721 gatttcgttc ttcgatcaat tgttcaatct cttcatctaa taactcttct gctgtaaata
    66781 aaataccgaa gatcgaaagc cattgcgaga ataaagcttc tccttgtgcc aagacagcgg
    66841 cagaaacttt cggctggtct agataagtgt tcagccactt agcaagctca tagaccactg
    66901 tgatcccatt tgctgcatta aaatcatcgt ccatttcttc gatgaatcgc tgttctaaat
    66961 tttctaacaa agcgatttta tccgcatcat ctgccaaatt ctctgaggca gtttcttggc
    67021 ggaatttcaa attgtcaaac gtattcttca gtcgttgtaa attggtggct gcttctttca
    67081 tcgtcgtttc actgtagcgg atcggacgac ggtattgtgt ggtcgccatg aagaaacgca
    67141 agacttgtgg atcaacgttt ttgatcattt catgtacagt gatgaaattc cctagagatt
    67201 tactcatttt ttcatcgtct tcgccaatcg ttacatagcc attgtgcatc cagtaattag
    67261 cgaatttttt ccctgttttc gcttcacttt gtgcgatttc attttcatga tgaggaaatt
    67321 ctaaatcttg cccgccacca tggatatcga tcgtttctcc taaatgtttt gttgccataa
    67381 cggaacattc aatatgccaa ccgggacgtc ctttgcccca tggtgaatcc caagaaatct
    67441 cgccaggttt tgcttgtttc cataaagcga aatctaatgg gtcttctttt tgctgctgtt
    67501 cttcccctgt acgctgactt gctccgactt ccagttcatc gatggattgg tcacttaatt
    67561 tcccataatt ttcaaattta cgggtacggt aatacacatc acctgaagat tcataagcat
    67621 agcctttttc aaccaacact tgaataaatg ctaaaatatc tggcatatga tccatgactc
    67681 ttggatgcag tgtagcaggc tcgacattca acgctttcgt atcttcttca aatgctcgga
    67741 tgaaacgatc agcaacttct ggtgctgtaa tacctaattc gtttgctgta cggatgattt
    67801 tatcgtctac atccgtgaaa ttcgatacga aatcgacttt atagcctcga tattcaaaat
    67861 agcgtcgaat tgtatcgaaa gcaatggtgc tacgagcatt tccgatatgg atataattat
    67921 acacagtcgg tccgcagaca tacataccga catgtccctt ttgtataggg atgaattctt
    67981 ctttttttct ggtcaatgta ttgtagattt ttatcattct gatctcctca ctttttctcc
    68041 tttgattcga acgacttttg ctggtactcc taccgctgta gcgtcgtctg gaacatcttt
    68101 caacacaacg gcacctgcac cgattttggc gttttttccg atcgttaccg gtcctaatat
    68161 ctgcgcattc gcagagagca tggctccttg tttaacagtt gggtgtcttt tacccgtttc
    68221 ttttcctgtg ccgcctaatg ttacgccatg gaataaaatc acatcgtcct cgatttctgc
    68281 ggtttcgcca atgacgattc ccattccatg gtcgatgaac acgccagttc caatcgttgc
    68341 tcctggatgg atctcaacac cagttaggaa acgccagaat tgagcattga tcttcgccaa
    68401 taaaaagagc cggtgctgat ataaaaaatg agagaaacga tgccaaaaca aggcatgaaa
    68461 accagggtat gtcaaaacga tctcagctgt cgaacgtgca gccggatcgt ttctctttgc
    68521 tgcatcaatc gctcgggtaa accaactcat gactttccac tcctttcgta agaattttat
    68581 gtaggaaatc atcttcttat aaagaaaaga agcgcctttt aaataagttt ccttatcaaa
    68641 agacgctttc cgcgtggttc cacttttctt cataatcaat gattatctct gacagctaac
    68701 gcctgttata cgttcttggc tactttgttt cctataaaac agtttttcct gttttctgtg
    68761 tttcgccaag accactccca gaggcatttc ggcaaccatt cattgatacc ttgcaccacc
    68821 cggtatctct cttgtaatga tcagctgctt acttttttct gttcatcgtg tttagttcag
    68881 tacttgattt aaatgtgcta atgatttttc acgaccaagc aattcgatcg tttcaggcaa
    68941 ttctggacca tgcatttgtc ctgatacagc tacacggatt ggcatgaaaa gattttttcc
    69001 ttttacgcca gtttcttttt gaacagcttt gatggcagct ttgacagttg gagcatctac
    69061 tacttccatt tgttctagct gtgctttgaa tgcgtggaga acagtaggaa ctgtttcacc
    69121 agcaagtact tcttttgctg cttcattcaa tacaggatgt tcattgaaaa atagcgtaga
    69181 cagatcaacg atttctgcag catagctcat ttgaggttga tacaggctaa cgatcttctt
    69241 cacccattcg attgtctttt catctgggtt ttctgctaca cgtccatcag cgattagata
    69301 aggcagacac atgtcagtaa atgcatctag atccattgct ttgatgtaat ggttgtttac
    69361 ccattgcagt tttttcgcat cgaaagctgc gggtgattta cttaggcgtt ttggatcgaa
    69421 cattttgatc aattcttggt gttcgaagat ttcgtcttcg cccacaggtg accagcccaa
    69481 taatgcaata aagttgaaca ttgcatctgg tagatagcct aattcgcgat attgttcgat
    69541 aaattgcaag attgattcgt cacgtttgct tagtttttta cctgtttcac tgttgatgat
    69601 caatgtcata tgtccgaagg ttggtggtgt ccagccaaat gcttcataga tcatcagttg
    69661 ttttggtgta ttggcaatat ggtcatctcc acgtaaaacg tgagtgattt tcatcaaatg
    69721 atcatcgacc gcaacagcaa aattataagt tggcatacca tcgcgttttt gtatgacaaa
    69781 gtcgccaccg atattatcgg attcgaacga aatagcgcct ttcaccatat ctgtaaatgc
    69841 gtattctgta ttgcgaggca cacggaaacg tacaacagat tctagacctt gtgcttcttt
    69901 ttctgcttgt tcttcaggtg tcaagttcgc acatgttcct gcgtaatgag gcatttctcc
    69961 tcttgcgcgt tgtgcttccc gttctgcttc taattcttct tctgtgcaat agcatttgta
    70021 tgctcgattg ctagcaagca gctgatcaat cagcggttga tagatttctt tacgttcaga
    70081 ttgacggtaa gggccgtatt ctccaggatt ttcaggagat tcatcccaat tcattcccaa
    70141 ccaagcaagg ttttccaact ggcttttttc gccatcttcg atattacgtt tttggtcagt
    70201 atcctcaata cgaataataa agtctccatc attgtggcgg gcaaacaaat aattgaataa
    70261 tgcagttctt gcatttccaa tatgcaggtg cccagttgga cttggtgcat agcgtacgcg
    70321 tactttcgtc attttcttcc tcttctttca aactagactt tgactaacag caaaaattcc
    70381 gtcagttacg gcttctcaaa tatcatttat ttaaagccac tcagcacaaa ttttaccttt
    70441 tctaaggtaa atagtaaagc caactggttg aatttcctta ccagttggct gaatttcttt
    70501 tttattttga ttgtttagtc tttttctctg tctctttttt attgtcgatt cctcgtcctg
    70561 catgtgcagg tttagcaaag atcatgcgtc cagcagctgt ttgaagggca cttgttacaa
    70621 cgacttcgat acgttcattc atgtaatgct gtccatcttc tacgacaacc atcgtgccgt
    70681 catcaaggta ggctactcct tgttggcgtt ctgtcccggc ttttactact agaacattca
    70741 tcgtttcacc agggatgacg actggtttta cggcatttgc caacgcattg atattaagaa
    70801 caggtacatt ttggaattca gagactttat tcaagttata gtcattggtt acaatgacac
    70861 catctaaaag cttagccaat ttgatcaatt tgctgtctac ttcactgata tcttcaaagt
    70921 ctccatcgta catttcgaca gatataccct cttctttttg caaggcattt aggatatcta
    70981 atccgcgacg accacgcaca cgtttcaaac tatcccctga gtccgcgatg tattgtagtt
    71041 cgtaaagaac aaaattaggg atcatcaagg ttccttctaa gaatccagtc tttgtaatat
    71101 cataaatccg accgtcaatg atcacgcttg tatccaagat tttatattta tggaaatttt
    71161 ctcctgattt tcgttctaac agttgactct caacttgact agctgtttct tgctcgattt
    71221 ttttgcttcg tgaaccaaaa actttcttcc attcttcgat tcgtgtcgtt cccattctca
    71281 atcccagata gcctaagatg atcatcagta aaatcggcaa tacactattg acgaatggaa
    71341 tttccatatt gtaaagaggg gtcgagatca caacacctaa agtcaatccg atgatcgcac
    71401 cgatcgcacc gaagagaaga taagtcaagc tgacctcact tagtttttgt tctacttgtt
    71461 tgataatagc tgagatatgt ttggccaaca gcaaagataa taaaaagaaa ataagtgcgc
    71521 ctaacaggct gttggtaaat gtattattca gccatccgtt tgactgttga ccgattgcct
    71581 gccaagctga gggtaaaaat gaaataccca agcttgcgcc gacaatgatc atcagcaaag
    71641 taatgacacg tttttgcatc gtttttcctc cgtttcgaca atcatttatt agttagcgga
    71701 acacacgctt caacgtttca gccaaagttg ctactccaac tatctcgatt ccttttggcg
    71761 cttcccagtt acctaagttg tttttaggta ggtatacttt tgtgaagccg agtttttgga
    71821 cttctttgac tcgttgttca atatgactga cacgtctgat ttctccagtc agtccaattt
    71881 caccgatgaa acattccgtt ggctgtgttc ctttttcttt atagcttgaa gcaatactga
    71941 cagcgatagc taaatcaatc gctggttcat ttaattttac cccacctgca gcttttaagt
    72001 aagcatcttg attctgaaga agcaacccag ctcttttttc cagcactgcc atgatcagag
    72061 atacccgatt gaaatcaaga cctgttgttg ttcgtttggc atttccgaac atagtaggtg
    72121 tgactaatgc ttggatctct accaaaattg gacgtgtccc ttccattgcc acaacgatag
    72181 cagagccagt tgcaccgtct aggcgttctt ctaagaaaat ctgtgaagga ttagcgactt
    72241 cttccaatcc atgctcatgc atttcaaaaa tcccaatctc attcgttgag ccaaatcggt
    72301 tttttactgc tcgcaaaatc cgaaaactat gatgttgttc accttcaaaa tataacaccg
    72361 tatccaccat atgttctaac attcttgggc cggcgatcga gccttctttg gtaacatgac
    72421 cgacgataaa aatggctatc ccatttgttt tagcgatttt gagtagttct gcagtggttt
    72481 ctcttacttg gctgacactt cctgccacac ttgtgatgtc tggctgcgtc atcgtttgga
    72541 tggaatcaat gataacataa tcaggggaga tatgttcgat ggcacgactg atttcgttca
    72601 tatctgtttc agcgtataga taaaattctg tgttgatact tccgaggcgt tccgcgcgta
    72661 attttatctg ctctgcgctt tcttcgccgg atacatataa gacttttccg cctatggctg
    72721 ctaattgctg agaaacttgt aacagcaaag tggatttccc gatacctgga tcgccaccaa
    72781 tcaagaccat agaccctggc accacacctc cgcctaacac acggttcagt tcttctaatt
    72841 ttgttttgat ccgaggttct tttttaggga cgacgtctgc gatttttgtt ggttttgctt
    72901 tttctcctgt caaacttgtc cgagttctgc ggtccgttgt atcttgttcg atttcttcga
    72961 ccatcgtatt ccattttccg caatttgggc agcgtcccaa gaacttaggc gacacatacc
    73021 cgcaattttg gcaaacaaat tgtacttttg atttttttgc cattgtaccg cctcctttta
    73081 tcctaatcat gagacattaa atcaagctta agtatcttta acgttttatt tactggaaga
    73141 accaaatccg ccttgacgtt gagcagtcgt ttgatcttga tctgctttta aaaacggcaa
    73201 aaagatccct tggccgatac gctcgccttt tttgatcact acatccttga aaccaaagtt
    73261 ggtgaattgg aacatgatat ggccttcatt tgcctcatta ttgtaataat cactgtcaat
    73321 cacacctact ccgtttgtca acactaaaaa ccgcttcaac ggattgcttg aacggttagc
    73381 aagctgcaaa aattcatctt ctcccatgta agctttgatt ccagtaggca cgagggttgg
    73441 tttcaattgt ttttcatttt ctgatacatc ttttttcaat ccatctgcga ctgtttccaa
    73501 cccctttttc cagcctgctt tccagatact tggaatcacg acctcttctg ctgcttcaaa
    73561 atcatagcca gcagcatgat gtgtagcgcg ctgcggtaga ttgatatttt gatctttata
    73621 tttagaaata acttcaaatc ctctttttct caccggtttt cct
//
LOCUS       DAKCAA010000007        71236 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000007 DAKCAA010000000
VERSION     DAKCAA010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 71236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.007"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..282)
                     /locus_tag="OUE31_000527"
     CDS             complement(<1..282)
                     /locus_tag="OUE31_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221561.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(295..858)
                     /locus_tag="OUE31_000528"
     CDS             complement(295..858)
                     /locus_tag="OUE31_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCU0221562.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            1086..1748
                     /locus_tag="OUE31_000529"
     CDS             1086..1748
                     /locus_tag="OUE31_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HCU0221563.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            1872..3068
                     /locus_tag="OUE31_000530"
     CDS             1872..3068
                     /locus_tag="OUE31_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HCU0221564.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(3169..4545)
                     /locus_tag="OUE31_000531"
     CDS             complement(3169..4545)
                     /locus_tag="OUE31_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0221565.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(4582..5448)
                     /locus_tag="OUE31_000532"
     CDS             complement(4582..5448)
                     /locus_tag="OUE31_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HCU0221566.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(5537..6562)
                     /locus_tag="OUE31_000533"
     CDS             complement(5537..6562)
                     /locus_tag="OUE31_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCU0221567.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(6580..7254)
                     /locus_tag="OUE31_000534"
     CDS             complement(6580..7254)
                     /locus_tag="OUE31_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0221568.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(7438..8331)
                     /locus_tag="OUE31_000535"
     CDS             complement(7438..8331)
                     /locus_tag="OUE31_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCU0221569.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(8405..10102)
                     /locus_tag="OUE31_000536"
     CDS             complement(8405..10102)
                     /locus_tag="OUE31_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCU0221570.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(10095..11408)
                     /locus_tag="OUE31_000537"
     CDS             complement(10095..11408)
                     /locus_tag="OUE31_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCU0221571.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(11408..15445)
                     /locus_tag="OUE31_000538"
     CDS             complement(11408..15445)
                     /locus_tag="OUE31_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCU0221572.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(15458..15916)
                     /locus_tag="OUE31_000539"
     CDS             complement(15458..15916)
                     /locus_tag="OUE31_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCU0221573.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(16214..16732)
                     /locus_tag="OUE31_000540"
     CDS             complement(16214..16732)
                     /locus_tag="OUE31_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCU0221574.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(16734..17351)
                     /locus_tag="OUE31_000541"
     CDS             complement(16734..17351)
                     /locus_tag="OUE31_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HCU0221575.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(17348..18202)
                     /locus_tag="OUE31_000542"
     CDS             complement(17348..18202)
                     /locus_tag="OUE31_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCU0221576.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(18199..19110)
                     /locus_tag="OUE31_000543"
     CDS             complement(18199..19110)
                     /locus_tag="OUE31_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0221577.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(19151..20485)
                     /locus_tag="OUE31_000544"
     CDS             complement(19151..20485)
                     /locus_tag="OUE31_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCU0221578.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            20693..21523
                     /locus_tag="OUE31_000545"
     CDS             20693..21523
                     /locus_tag="OUE31_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCU0221579.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(21767..22049)
                     /locus_tag="OUE31_000546"
                     /pseudo
     CDS             complement(21767..22049)
                     /locus_tag="OUE31_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011066964.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(22207..22401)
                     /locus_tag="OUE31_000547"
     CDS             complement(22207..22401)
                     /locus_tag="OUE31_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221580.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(22906..23091)
                     /locus_tag="OUE31_000548"
     CDS             complement(22906..23091)
                     /locus_tag="OUE31_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221581.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(23941..24282)
                     /locus_tag="OUE31_000549"
     CDS             complement(23941..24282)
                     /locus_tag="OUE31_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCU0221582.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(24282..24512)
                     /locus_tag="OUE31_000550"
     CDS             complement(24282..24512)
                     /locus_tag="OUE31_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCU0221583.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            24799..25137
                     /locus_tag="OUE31_000551"
     CDS             24799..25137
                     /locus_tag="OUE31_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221584.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(25342..25581)
                     /locus_tag="OUE31_000552"
     CDS             complement(25342..25581)
                     /locus_tag="OUE31_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCU0221585.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(25557..25904)
                     /locus_tag="OUE31_000553"
     CDS             complement(25557..25904)
                     /locus_tag="OUE31_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCU0221586.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(26636..27217)
                     /locus_tag="OUE31_000554"
     CDS             complement(26636..27217)
                     /locus_tag="OUE31_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCU0221587.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(27400..28026)
                     /locus_tag="OUE31_000555"
     CDS             complement(27400..28026)
                     /locus_tag="OUE31_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCU0221588.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(28048..29379)
                     /locus_tag="OUE31_000556"
     CDS             complement(28048..29379)
                     /locus_tag="OUE31_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HCU0221589.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(29534..29935)
                     /locus_tag="OUE31_000557"
     CDS             complement(29534..29935)
                     /locus_tag="OUE31_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCU0221590.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(30021..30227)
                     /locus_tag="OUE31_000558"
     CDS             complement(30021..30227)
                     /locus_tag="OUE31_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221591.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(30322..31824)
                     /locus_tag="OUE31_000559"
     CDS             complement(30322..31824)
                     /locus_tag="OUE31_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HCU0221592.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(31842..32297)
                     /gene="argR"
                     /locus_tag="OUE31_000560"
     CDS             complement(31842..32297)
                     /gene="argR"
                     /locus_tag="OUE31_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCU0221593.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(32395..33012)
                     /locus_tag="OUE31_000561"
     CDS             complement(32395..33012)
                     /locus_tag="OUE31_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HCU0221594.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            33233..34606
                     /locus_tag="OUE31_000562"
     CDS             33233..34606
                     /locus_tag="OUE31_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0221595.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            34681..35793
                     /locus_tag="OUE31_000563"
     CDS             34681..35793
                     /locus_tag="OUE31_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCU0221596.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(35865..37502)
                     /locus_tag="OUE31_000564"
     CDS             complement(35865..37502)
                     /locus_tag="OUE31_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HCU0221597.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(37670..38278)
                     /locus_tag="OUE31_000565"
     CDS             complement(37670..38278)
                     /locus_tag="OUE31_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCU0221598.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(38662..39813)
                     /gene="queG"
                     /locus_tag="OUE31_000566"
     CDS             complement(38662..39813)
                     /gene="queG"
                     /locus_tag="OUE31_000566"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HCU0221599.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(39832..40584)
                     /locus_tag="OUE31_000567"
     CDS             complement(39832..40584)
                     /locus_tag="OUE31_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221600.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(40725..41675)
                     /locus_tag="OUE31_000568"
     CDS             complement(40725..41675)
                     /locus_tag="OUE31_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCU0221601.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(41676..42515)
                     /locus_tag="OUE31_000569"
     CDS             complement(41676..42515)
                     /locus_tag="OUE31_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCU0221602.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(42512..43258)
                     /locus_tag="OUE31_000570"
     CDS             complement(42512..43258)
                     /locus_tag="OUE31_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCU0221603.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            43496..44867
                     /locus_tag="OUE31_000571"
                     /pseudo
     CDS             43496..44867
                     /locus_tag="OUE31_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(44922..45818)
                     /locus_tag="OUE31_000572"
     CDS             complement(44922..45818)
                     /locus_tag="OUE31_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCU0221604.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(45932..46102)
                     /locus_tag="OUE31_000573"
     CDS             complement(45932..46102)
                     /locus_tag="OUE31_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221605.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(46099..46776)
                     /locus_tag="OUE31_000574"
     CDS             complement(46099..46776)
                     /locus_tag="OUE31_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCU0221606.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(46867..47772)
                     /locus_tag="OUE31_000575"
     CDS             complement(46867..47772)
                     /locus_tag="OUE31_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCU0221607.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            47947..49401
                     /locus_tag="OUE31_000576"
     CDS             47947..49401
                     /locus_tag="OUE31_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0221608.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            49417..50448
                     /locus_tag="OUE31_000577"
     CDS             49417..50448
                     /locus_tag="OUE31_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCU0221609.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            50455..51642
                     /locus_tag="OUE31_000578"
     CDS             50455..51642
                     /locus_tag="OUE31_000578"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HCU0221610.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            51798..53180
                     /locus_tag="OUE31_000579"
     CDS             51798..53180
                     /locus_tag="OUE31_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCU0221611.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            53307..53537
                     /locus_tag="OUE31_000580"
     CDS             53307..53537
                     /locus_tag="OUE31_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221612.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(53737..54405)
                     /locus_tag="OUE31_000581"
     CDS             complement(53737..54405)
                     /locus_tag="OUE31_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HCU0221613.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(54594..55391)
                     /locus_tag="OUE31_000582"
                     /pseudo
     CDS             complement(54594..55391)
                     /locus_tag="OUE31_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(55672..57051)
                     /locus_tag="OUE31_000583"
     CDS             complement(55672..57051)
                     /locus_tag="OUE31_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCU0221614.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(57226..58395)
                     /locus_tag="OUE31_000584"
     CDS             complement(57226..58395)
                     /locus_tag="OUE31_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCU0221615.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(58370..59521)
                     /locus_tag="OUE31_000585"
     CDS             complement(58370..59521)
                     /locus_tag="OUE31_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCU0221616.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(59481..60842)
                     /locus_tag="OUE31_000586"
     CDS             complement(59481..60842)
                     /locus_tag="OUE31_000586"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HCU0221617.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(60839..61840)
                     /locus_tag="OUE31_000587"
     CDS             complement(60839..61840)
                     /locus_tag="OUE31_000587"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCU0221618.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(61856..62551)
                     /gene="dapD"
                     /locus_tag="OUE31_000588"
     CDS             complement(61856..62551)
                     /gene="dapD"
                     /locus_tag="OUE31_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HCU0221619.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(62557..63273)
                     /locus_tag="OUE31_000589"
     CDS             complement(62557..63273)
                     /locus_tag="OUE31_000589"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HCU0221620.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(63270..64151)
                     /locus_tag="OUE31_000590"
     CDS             complement(63270..64151)
                     /locus_tag="OUE31_000590"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCU0221621.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(64154..64954)
                     /gene="dapF"
                     /locus_tag="OUE31_000591"
     CDS             complement(64154..64954)
                     /gene="dapF"
                     /locus_tag="OUE31_000591"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HCU0221622.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(64941..66200)
                     /gene="lysA"
                     /locus_tag="OUE31_000592"
     CDS             complement(64941..66200)
                     /gene="lysA"
                     /locus_tag="OUE31_000592"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HCU0221623.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(66415..66585)
                     /locus_tag="OUE31_000593"
     CDS             complement(66415..66585)
                     /locus_tag="OUE31_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221624.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            complement(66686..67249)
                     /gene="efp"
                     /locus_tag="OUE31_000594"
     CDS             complement(66686..67249)
                     /gene="efp"
                     /locus_tag="OUE31_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HCU0221625.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            67677..68594
                     /locus_tag="OUE31_000595"
     CDS             67677..68594
                     /locus_tag="OUE31_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HCU0221626.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            68607..69752
                     /locus_tag="OUE31_000596"
     CDS             68607..69752
                     /locus_tag="OUE31_000596"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HCU0221627.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            69923..70381
                     /locus_tag="OUE31_000597"
     CDS             69923..70381
                     /locus_tag="OUE31_000597"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HCU0221628.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            70540..71010
                     /locus_tag="OUE31_000598"
     CDS             70540..71010
                     /locus_tag="OUE31_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HCU0221629.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(71063..71178)
                     /gene="rrf"
                     /locus_tag="OUE31_000599"
     rRNA            complement(71063..71178)
                     /gene="rrf"
                     /locus_tag="OUE31_000599"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        20458 a        14930 c        12613 g        23235 t
ORIGIN      
        1 tataaatgcg attgctaaaa aaaccacaca taacattagg ataacaataa taagagattt
       61 catcaaaaaa gagttccatt tggtcgtctt ttcccgttcg ctgatccttg ttttcgtgat
      121 tggtttattc tttttgcttt ctttacgata aaagctggca atcttttttt cttcttgctg
      181 ataagctgtt tctgcttttc gctgtttttt taatgactcg cttgcttgtg cttgttgtcg
      241 cttgcgaagt tcgcttcgcg taataagcgg tcctttggcc ataagccgat ccctctactt
      301 tcctttggtc aatagttccc agtattgaat cgcataaatc gtctttgcat cacaaatcaa
      361 ctgatctttc atcgcttgtt gcgcctcttc aagagttaga tgatacaact ccagtacttc
      421 gtcttcatct tgtgctaaag gattctcgac cttctctacc ccttgtgcat gataaatatg
      481 aaggacttca tttgcaaaac ctggtgaaag atacatcgaa gtaagatggc tcagcgactt
      541 cgcacgatag ccagtttctt cttctaattc tctagctgct gtcatttcgg gattttgtcc
      601 ttctcctgga tcgatttttc cagctggaat ctccaaaatc actttttcta aaggttttcg
      661 aaattgtttg acaagaagca gacgatcttg ttcgtcaaaa gcaatgatcc cgacaccgcc
      721 aggatgaaat accagttctc tcttcgaagt tcctccatct ggcaaacgaa cttcgtctac
      781 agcaacatca ataatttttc cgctatagat ttctttgcga ctgattgttt tttcttcaaa
      841 ttgctcattg ttcagcatat cttctcctgc tttctttgta atcataactg cttttttttc
      901 atttttcaat ttttctcaaa aactccttat tagtttacca tagataaacc ttagattttc
      961 tctaaatata gaaaatcctt ctttagtccg atactctttc tagtagtccg tatgctaaaa
     1021 taagtatgta atcgaataac gaaaagaatt caatactcaa cgataaatga catggagggt
     1081 ttattatgat aaaacgaaat tggccgtggc ttctagcatt ggtcttgcta tttctctttg
     1141 tccgaaacaa tagtttttct tttgttctag gacttttatt gataggtgta gttttagttt
     1201 tgtggggact ctttggttcg cgcaggaaaa agggaaaaca agaagaaatt cctgcactga
     1261 ctgacgaact tgaaactcac tatgaaaaaa gcggtatgac agcgaatgaa atttcatttt
     1321 ttcgacaaac aatgaatcaa acaaaaaatg agatcaatca attgcaaatg aatatgcagc
     1381 agacagccaa acttaaagca atcgatctcc gccatgatcc agtcaaagca gcgaaagctt
     1441 tattcaaaga attggtgaaa gaaccaaacc gactgcatga agcaagtcag tttctttata
     1501 cgcatctgcc gaatctagtt gatttgacaa ataagtataa tgagatcaat gaccatgaga
     1561 tcaaaaacaa acagacctat gaaaaactag aagaaagcgc gcagatcatc gaccagctgt
     1621 cagctttaat cgcacaagat tatcaaaaat tcgttgctga ggatctagat gatatcgacg
     1681 tagagatatc tgttgcgaaa cagagcttaa agcgtgataa taaatatgaa ccagaacaaa
     1741 aggattaact cttttgttca taaaagaaga ctcggaacat tcagatgatg tctggctgtt
     1801 tcgagtactt tttctaaagt agagacattc atgtaagaat cgagaacaga ttcaacaagg
     1861 aggaattttt tatggatcat aaaccgactg aaacaaaaga tgttacacca gttaacgata
     1921 cacttgaaga tttattgaac aacccgtttt caactccaac agatacgctg accacttcac
     1981 aacaagcgga gattgatcag ctccaagagc aacagacagc tgctcgttta attgacaaac
     2041 taccggcgga acgccaagaa caagctaaac agctagcagc aaaaatcgat gctaatgatg
     2101 cacagtctgt catcagctac ggatcggctg cccaagcaaa attaagtgaa ttctcacaat
     2161 cgatgttgaa tcatgtgcaa gcacaagata ttggtcctgt aggagattcc ttaactgaac
     2221 tgatgtatcg tctccaagaa gccaatcctg acgaactgcg tgccggagaa gggaacatct
     2281 tccagcgtgt cttcgggaag gtcaaacaat cgatctatga agtgacagca aaatatcaaa
     2341 agattggtgc acaaattgac aagatttcag tgaaattaga taaagaaaaa gacggtctgc
     2401 taaaagataa tctgatgtta gaacagcttt accagaaaaa caaagactac tttgatgcac
     2461 tgaatattta tatcgctgct ggagaattga aaatggaaga acttcaaaca acgatcattc
     2521 cagaagcgat gaaaagagca gaagaaactg gcgatcagat ggatgttcag attgccaatg
     2581 attacacgca attcctagat cgtctggata aacgtacgca tgatcttcgc ttagctagac
     2641 agatcacgat ccagcaagca ccacaaatcc gtttgatcca aaacacaaat caggccttgg
     2701 ctgaaaagat ccaagcatct atcgctacag ccattccgct gtggaaaaac caagtcgtga
     2761 tcgcattgac cttgcttcgt caaaaagatg cagtaactgc tcaacgccaa gtctctgaaa
     2821 caacaaacga cttattgaag aaaaattcag aaatgctgaa aatctcagcc atcgaaacag
     2881 cgaaagaaaa tgaacgtgga atcgtggata tcgagaccct tcaaaccact caaaatgatt
     2941 tgatcgaaac aatccaagag acattgcgta tccaaaaaga aggaaaagaa aaacgtcgtc
     3001 atgcagaagt agagcttgga cacatggaag aagatctgaa acaaaaactg ttggatttaa
     3061 cccaatagat cacctttcgc ttgttactaa aacaaacgcc caacaacagt ttattacaac
     3121 tgttgatggg cgtttttctt atctttcttc taacttctcc attggagtct atttctcatt
     3181 catcttgctg tgtccatagc catagccaaa ataaatgatc agtccaataa ccattacgat
     3241 accgaacacg atccatgtca cagtttgcag acgaagcatc aatacaatac aagtcaagat
     3301 ggagacgatt ggcaatagcg gaacgaatgg cactttgaat tctccagctt ttggtttgcc
     3361 aaacattttt ctcaacttca gtaagcctag actaacaagc atcaaatagg cgagcgccat
     3421 gatattcgtt agttccgcta atacattcaa tgggaaaaat ccggcaaaga atacagctgc
     3481 cacaccagcg gcataagtcg cttttttcgg tgtacgatgc ttttgatcga tttctgtcat
     3541 aaacttagga agtaagccat ccttgctgac agcaaacagt aaacgagcaa gtgaatacat
     3601 catcgagatc gttaccgtca gtagcgttaa aattgcccct acagcgatca ccgcgcccac
     3661 tgttccatgt cctacatacc tcattgcaaa agccactggg tcattgactc ctagttcagt
     3721 atacggaacg attcctgtca agatcagcgt cacgatgatg taaaggacag tagcaatcag
     3781 tatcgaacca atgattcctc ttggcacatc tttttgcggg tttttgactt cctcggctgc
     3841 cattgcaacg gcatcaaatc ccaagaaagc aaaaaacaca agagctgcac catctagcac
     3901 accggaaaaa ccaaaaggca tgaatggctg ccagttatca ggtttaacga aaaatattcc
     3961 tacaatgata aacaacgcga tgataccaaa tttgacatat accatggcat tattcaaacg
     4021 taatgctttc ttggcttcaa gcgacacgat gtaagtgacg aatatcacta cgagcaccgc
     4081 aatcaagtca atgtatgtac cattttccgg attgtacccg ccagttaatg cttgtggaag
     4141 ttcggcccct aaacttttca aaaaaccttg catatagcca gaccatccgg aagcaacaga
     4201 ggaaaccgct agtaaaaatt ccccgatcaa caaccaccct gtcagccagg cagcaaattc
     4261 accaaataca acatacagat aggcatatgg cccaccaatc actggcactc gcgaagcaaa
     4321 ttctgcgaaa cttagtccag acaaaatgac aacgattgca gctaagacaa atgaaagtga
     4381 cagtgctgga ccagcatttt gattggccgc aacccctgtc accacaaata ttcccgtacc
     4441 gatgatcgca ccaattccaa gcatgatcaa atcagacgtt tttagttctt ttttcatctc
     4501 actcgtatga ttgagattga tctctttctt acgaaacaaa tccattgaag ttcctcccca
     4561 ttttaggttg gaaaacagcg attaaactgt tttcatatac cctaaaagga taccacctaa
     4621 aatgactaaa aggcaaccaa caataacata aatgagctct tttttcgttt ttctttcgcc
     4681 aaggatgaaa atcccaccta aagtagagat aatgatcccc atttgtgaaa gtgagaagcc
     4741 aacagctaaa ccaagtgatt tgactgttag aagcatgcag atgtttccta agccccataa
     4801 taatccacag atcatgtttt tccacacaaa ctgatcgact ttaactttac ggaaagcaaa
     4861 gaagcttgcg cctaagatca ttccgatact ttgaggtaag ataattgaca tcgcatccaa
     4921 attcgcccag ttgacgatga tggtatatac accataacca atcgtagaga agatcaatgc
     4981 tctaaaaccc ttaccaaaat caagcatttt attatctgta tctatttttc cttcgtcatc
     5041 ttgtcgggca gtcaaatacg caccgcttac aagaagagct aaagcaataa taccgtatac
     5101 ataatctttc gtttgtgtcc attcatggaa gaaaacggct cccgcaatcg tattcaaaat
     5161 taattgaaaa ccagtagaca atggtagccc tacagaaaca cccatgtact tcattccatg
     5221 gaactgtcca ttttgtccaa cactccaagc taagccggat aaaaatccga tcaagaaaat
     5281 ccaaggggtg attacaggac taacaacgaa aaagacaact aaagaaaaca gaaatgcacc
     5341 gatcgtcatt cctagtgttt gttgattggc atcgccacca attttaccac ttactaaacc
     5401 aatactaccc catgccaaca tagggactaa tgctattaaa atttccataa ccaatctcct
     5461 tttatttcac atgataagaa acttatcagc gaaaacgtta acaacacaag cacttttttt
     5521 cgtttctaac gattttctaa cgtttttcat tataaaaatt taagattggg aaaaataaag
     5581 tcattgttgt cccttttcct tcagttgatt cagccgtcaa atggatacct aatttttcgg
     5641 ccagattttt tgctaaataa agtcctaatc ctgttgaatg tgttttgcta agtcgaccat
     5701 ttctcccagt aaatccctta tcaaagatcc gtttcaagtc ttccgctggg ataccgatcc
     5761 ctgaatcttt aactgaaagg ctgactcctt gcgcttcctt ttctatgctc acaatgatgt
     5821 ttccgtgatc cggcgtatat ttgatggcat tactaagcaa ttggttgaag ataaaagcga
     5881 tccatttagc atcggtcaaa acagtatgat cctcaccaac gatctcgtag cgaatatttt
     5941 tttggataaa ataatttgcc tgactgcgta tcacaggctg aatgattcct tttagtccat
     6001 attcttggat gaggtagtcc cgcgagaaac tgtcgagtct tgcataatac aaaacttgtt
     6061 ctacgtattc atcgattttt gataattcat tttctagtaa tgtatacttt tgatcgtcaa
     6121 tatcgaactc gatcgaacga actagcaatt tagaagcgga aagtggcact ttgatttcat
     6181 ggacccatga gtcaatataa tctttttggt cttgttgatt actgattgct gattgcatta
     6241 cttcttggtg ttcacggatc agctgattga tatattcttc taccagtttt tcttcttctg
     6301 tcctcccacc actcaaataa ttttgcaaag gggaagtttt ttgtatgtcg gctaattttc
     6361 cccaccatct tctcttgctc aagtaaccac ccagcagata aaaaatcaga aagacgccct
     6421 caatcaaagc taaataagca attgtgctca aatcaacttt gatgtttggc gccagccaca
     6481 tcacaaagat cgtcaatgca ataaaaaaca gccatcccaa gatcaatgtc cactgatctt
     6541 tcaaatattt aaaaaaattc atcttaaccg ctcatccttt cagggaacga tatatccctg
     6601 tcctactttt gtttcgatat atccttggat acctgcctgt tcgatttttc ggcgtaaccg
     6661 attgatgttg actgtcaatg tattgtcatc tacaaatcgt tcgtcatccc acagtgctcg
     6721 cagcaatttt tcccgactta agatctttcc attgtgcttc atcaaaataa ataatagacg
     6781 atattcattt ttgctcaaat caatgatctc tccgttgatt tccatacttc cgttgtcaac
     6841 attcaacgta atgccattgt ggctcatcat ttcactagat aattctgtgt agttgtaaga
     6901 acggcgaagt aatgcattga tttttgcaat cagtacatcg atttggaaat gttttgtcac
     6961 aaaatcatct gcccccatgt tcatagccat gatcatatcc atattcgtat tcctgctgga
     7021 gataaaaatg atcggtactt tcgatacttc acgtattttt tgacaccaat aatagccatc
     7081 caaaacggga agattaatat ctagtaatac aagctgtggt tcttctcttt caaagtctga
     7141 gaacacttga ttgaaatcgg tcgttccaaa ggtttcaaat tgccatttct caagttcctc
     7201 catgatcaat tgtcgaatga tctcttcgtc ttcgactacc atgatttttg ccataaaaaa
     7261 tccctccatc tttcttcttg ctactacaat atcaaagaag cccttgtgaa acaagttggc
     7321 ttacctggaa aatgtcattt tagcaaacgt taaaaaaaac tggaaatatg cgatttaatc
     7381 gcgtttgtct cttccaagca gcttaaattt attatgttat tcttaataat tggtctatta
     7441 tctgttattt ttctttcgtt gtttttgtct tttaaatttt cgataacacc aataaccgaa
     7501 aagcgttagc actagcaata tacctagaag gagtataagt aatcgataaa gatggtattt
     7561 ttttgtctgt tctatctttg aagagacttc ttctgtaaag ggaactcgtc ttcctgtcac
     7621 tagtaatcgg tgagtgttca cggtgtaagg tgtacaagtg ataagtgtga ctagatcctg
     7681 cttttctcta attgctaatg tatttgtttt tgttggaagg acaacaattt tctcaacgac
     7741 ttcataagcg agcatccgac catacacttc aagatagaat cggtcatctt gctccatttc
     7801 ttcaagatcc gtaaagagtt ttttctcagc aataccgcta tgggcggtaa tcacggaatg
     7861 tgtactctct cctccagttg gaaaagaggt gccttgcagg actgtcgctc ctctatctaa
     7921 caaaagatca ttcgtttcat caaataaagg caagctaaca ttgattttcg gaatatagat
     7981 ggctccgatc atatgttgtt cgtaatattc ttttcctgga ttttggacat ttctaaccgc
     8041 ttgctcaaaa ggatctttga cttgtcccat tcctgggatt actgatgtat gagcaagcgt
     8101 ctgatttttc ttttcatgca ctgctaattg ttgctcatgt ttttcttctt tatcgcgttc
     8161 aagctgcttt tgataattct cgatccttct ttgatccaaa taattgctga gagcatctgc
     8221 taaaaatgga tatgtaaaaa ctgcagctcc ggcaagaaac atcactgcca taaataattg
     8281 taataaaaga ctgatttggg tttgaggtct attacctatt ttctttttca ttttcttcac
     8341 cttcttattt aaaaaaactg cagcaacctt tataaaaccg attgctgcag cttatttttg
     8401 ttgcttatac ttcagacttc attttagatt tacggtacca gctgtacgct ccaatcatca
     8461 aacttattcc gattagtaag aatgccaaga gcccgttccc accagtagca ggaagtgacc
     8521 cgcgtttcat attcggtact ctttctggcc ctggattttc tactcctacg atctgaattt
     8581 cttcattata gcttccataa gagatgataa attcagtaaa ggctgcctca cctgttggaa
     8641 gtacataacc ttctggcgcc atggtctctt tcatttgata ggttccataa tctaaccctt
     8701 gaacctcaaa gtatccattt ccatctgcga caaattctgt tgcttgtccg cttgttgccc
     8761 actcaattct atctgctcct gattcataaa cagctaaagg cgactcccct ttataaaata
     8821 ttgcgtattc agaacggtct tcattccaca attcgaatct tgcatcttta agcaattcac
     8881 tgcttgatgc atcatatttt tcaaactttc ttccacctgt tgtgactttc tctggcggct
     8941 ctactccttc ttcataatca aattcatcat ttcgtccgat ttcaataacc gctgtgttgt
     9001 tatggaaatc atccgcttct agttctgtgg aaaccttcaa attatacgtg atcgttaaat
     9061 ctcctccacg tgcatctgct aatctaccta aagtatctac tttggctact ccattttctt
     9121 ctgtcaaaat cgtcacgaca aacccgttgc ttactacttc tactatataa tcttgtcctt
     9181 ttgttaaaat cgtctcgccg gctcgcactt ctatttcctg atcataataa gttagaccaa
     9241 ctgtaggcgt atctgtgatt ttgtaatttt tgataacagc gcttccgttt tcaaggacag
     9301 aatcgatgaa ataaggaata ggtgctgtga tcgtgtaaga agccgttttt cctctttcta
     9361 gatcaatata agaaatcgtt tcttgttctc cagcttcatt aataatcgtt acttgtctaa
     9421 ggtcgctttc ctctacattc atctgtttat ctgcttctct gatttcgttt ttcggataca
     9481 aatgcacatc tgtattgtat gtgtctttcc atgtagaacc atcccacacg ccatccacca
     9541 tatcaggcat catcactggc atcataacaa ccattggaga cgcgattctg gaaatatgag
     9601 ctggcgaata agtttctaag aaaagataga ctttatctct agaagaaggt gcttcttccg
     9661 tcacttggac ggtagagaat accgcttctc cagcttcatt cgttgtttgt ttgtcaatac
     9721 ttgtcagtcg atattttaaa aaccaacttt ctgtgtgccg tttttgaatc cattcaatcg
     9781 cttcggcaga attaagaccg tcttctcgtt ccggtgttaa aggattatct cgaatcaaat
     9841 cgtaatatac ttccgttacg tcaaacaaat caaaatcgac tcctggaata ttttcttcac
     9901 caaaatccgt agaaaccaat ccgctattcg gtcgttcttc cggaacagat gagaaacctt
     9961 ttttgtgtaa tgtaatcgtc acttcacttg gtttttgtgc gacttcttcg gctttgacta
    10021 gttttccgtt cccgaaaatc cctattcccg cagtaacgag taacagtaca ctcattcccg
    10081 tgacaatcat ttttttattc atttttttct ccccgttctt tttttattaa taaaacagca
    10141 cctaacaata aaagaattcc tagtaaagaa atcaacgttc ttgcttcatt cgtttgcggg
    10201 aatacggacc attttcctga ttgacctgga ttgcttggac cactcggctc tttcggtttg
    10261 tccgttgttt cttttacggt ctcgttataa acacgtggtg ttgcggattc ataggcagag
    10321 actggaactt tcccggattc taattcagcc atctcctgtc cgttaactac tacatattgt
    10381 ggttggcctt ttgcatccac ccaaaattca gggatgatga cctcgattct cttacttgct
    10441 tcatccatct cgtaaccttc cacacctttt aattcttcaa aataataggt gccagaaggc
    10501 aagaaacgtt gtcctgtcgt aacaaggccc tctttatccg aaatgaattt gcttacattt
    10561 ttgtcattca aaggatcatt gtctgctggt ttgatccatt gatttttcaa gtcattagca
    10621 ggagccatat ctaaataata tttcccccct tctatcatct gatatagagc aaaaacagca
    10681 ccttctaatg gttttccttt ttcagttgtt cctctttgac gtccatactt gaagaagtat
    10741 ggatctctta gataaccgac atttttagga tagatatgaa tctcttgcag ttcctcggtt
    10801 gattctgtcg ggtgataaat tggcaaaata gcagcaattg ggatagctgt ctgatcgata
    10861 tcaacatcca atccaacttc tggatcaatc gattcttcga aaatcaaata aactgcatcc
    10921 cgatcttggt ttttcttagg tgctttgata cgtgcaatcc cgtctcctaa tccgccaacc
    10981 gtatctttcc cagttgttac cgaagtccct atttggacaa gcctttcttc tgtgattagc
    11041 tgacggatat tgtttctgtt cgtttcagcg atttgctgga cgaattcttt aggagtcatg
    11101 ttttcagcag cttttttttc atgataataa tcggtcatgt cgtaaatggc aaatgtcgct
    11161 ccatttagtg gcaccgtctg tgaaatgata tctgctgttt cccctgcttc ctcagagata
    11221 gccaagccat cattttcatg gtattcaaat tgatcgttat aatcgatatc tcgaatcatc
    11281 cgtttatgca acacgaattc cacgacatct tcccctgatt cttctgccga catcgcatgt
    11341 ggaagaagga ctgctgcaag cggtagtaaa acaagtaatt gaagcatcaa acacaacagc
    11401 tttttcatta ccttgctccc tcctttttag attgtctgac aaacaaacca taggctgctc
    11461 ctgcaagcgc catgaagaat gcagcaagca ggatatagaa taatcgtccg gatcctcctg
    11521 tagcaggcaa cggattttca ggatcgttcc cgacactaag ctgtaatctg attcgatttg
    11581 tctccaaaag ttcatattct aactcttgct gtagatcagg cgtctctgct tcttcgtttg
    11641 gataatacga aatctcaact tttagtgtac ccgcttcttt tcctggaact acccgatcat
    11701 tttctatgtc aggttcttct cgataactaa tttctaaaat aaagtaacct ggaagttttc
    11761 tatagctgtc aggtgacttc acttccttga tccgatagac cccttccaac aagtctgaag
    11821 cattgaatag ggaagaatcg tttggatctg gtgccaagcc tccctcgatg atttcatact
    11881 ctcctgcact attttgtttc tcaattgaaa attctgcgcc ttcaagacgt cggctattca
    11941 tactgtcaat tttcaaaagt tccaaatcga ttggcgctag ttcatcttct aaggttactt
    12001 gtagtacacc atcgatgatt tcatagcctt ccggcaaggg agcagtttcg tcttcgatga
    12061 ccgtatcttc aatgataaac ttaccttctt cattcagtgc aaactggaac acttgatcag
    12121 atagccgata cccatttggt gcgacagatt ccgagacctc atattcacca atagacagat
    12181 gcagaggttg gtcgtaattt aaatcgacat acttttctac tcctacggca cgagaataga
    12241 agtatccgat cccaggcaaa cgtttcgatt cttctggttc taacggatta ccagtgtatg
    12301 ctcgatacag cgggaaggaa gaatccccca ctttcctgat atcgaaacct gcaccatcta
    12361 atgtatggcc ttcatggtct aattttctaa ctcggatctc ccgataatca aacgtattgt
    12421 aagcagtgaa tgctacccat aaacgatcct cttcatctgt tgtatacgtg agatattgcc
    12481 aattttcttc acctgtttgc ttgagttgga tagtccctat agcattatcg taaagtcgca
    12541 agatccatgt gtcattttca tcaggttctt tgaaaccttc tgggttctgg ctctcaatga
    12601 ttttgtattc tgcatagttg gtagtttctt cactatcctt ataaacaaat gaatctggct
    12661 ctccgattgg atgaataact ttctcaccat ccacgattac atatttcccg tcttcatcta
    12721 ctgaatagaa cgtgagtctc cctttctctt cctctacttc gttcacacca gaaagccctt
    12781 tcgctactgg atatccgatt tccagtccgt taccatctgt ttcataaagt tcaaactctg
    12841 cgccattgat tggcatatta ctgccttcaa ttagtttatt gatattcatg tggattggct
    12901 tgaattcatt tcgcatttcc agtttgacat acaactcatc atactctgtg ccttctatgt
    12961 taggctcttg tacaacagaa agcttgtgat attctccttc ataataggaa ttcggatctt
    13021 taccttccgg tccgccgact ctcgaaccag atgtatattc atctacaagc tcgtagtgac
    13081 ctaacatctc atcttcgttg gctgcatatt ttttgatttg gaattgatac gtctcatcta
    13141 ctaactgata acgtggtggt ccagcgatct ctctgatcca aaatatgtcg ctgactgctc
    13201 cagtttcatc tcctaaaatc ggcatcttcg tttcaaagat cgctattccg tccgtggtag
    13261 ttttacttgt ttcgattggt tcggcttccc cactctctgg attttggtca tataatgcaa
    13321 attcgactcc agccaacggc tcgccatttt gacccttctt gctgacttgg aaattacggc
    13381 ctttatgttc gtaacgaatg gaagaagatg ggaaatacat ccgtccagta gtgatatcat
    13441 tctcataatc ctccaggttc tgaatatagg ccatattgtt cactgtgcaa aaatttccgt
    13501 cttgagctcc cgcatcaagt tttacttggt acttgatcct gaccatttcc ccttcaccta
    13561 aagaaatcgg agaaaattta taagcttggt tttcccgtcc gacatacgtt gtcggagtcg
    13621 ccactacttc tggtggggct tgtccatgac gttcttcatc ccatatttct ggctcttggt
    13681 acttcatgcc gttttctcct ggatctagat ggtaaaactg aatatctgcc gatctgccag
    13741 ctccaaatgg tgagacatta aaaccagttt catcataaag tgtggcttgc tggatcgttc
    13801 tcttgaaggt agaagagata tcctccaagg ctgtaacaat gtcattcttg ttgttcgcat
    13861 tgtaatatcg cggtgttacg ccatcttctt ctaaatcagc aatatttttc aatacatttc
    13921 gtccaatagc atctagtcgt tgtctcccgc taacgtttcc atcgattcct aaaccaatgg
    13981 agaagatact tggcgggttc tcttgatact tgtttttcag ccaatgatga taagcaactg
    14041 tgttgatcgc agatgacttt tcttgcgaag taggactgcc attcgtattg ttattagaag
    14101 aaccatcacc aacccagtga gtcgctttat tatctccttc ttttacctct ccataacgat
    14161 agtgtacatt tacttcatct tctggacggt taaagtcaga tgcataggta actggatgag
    14221 taaaccctgc attagaagta ttcccagaaa actcctcaaa atttctgaac aaaacgtcat
    14281 tatcttcagc aatcttatct tccatcacag tccagttgct ccaagctcca ttagtgctcg
    14341 tacgataact tgactgaatc ggtgcataac tgaaggtcgg tgtcccatct cccacaacga
    14401 ttaggatttt ttctggattt ctattttctc cgccattgtc tttatacaat gtttcatagc
    14461 catttttaag ccctagtgta agcggagttc ctccgattgg tgtacgattt aatgctgtat
    14521 tctcacttcc cgtcaaacga ttgatatcat ttgtcaatgg aaagatgtcc gaactgattt
    14581 gctcatggtt attgatagct gtactattat ggtaaaaatt caccataccg attcgaatat
    14641 ccagactcgg gtcagagagc agatctttac tcatttcgtt tactgcctca atcaacgcag
    14701 catttttagt ttgactattg gtcccagcgg ttaattcact catactcgct gacttatcta
    14761 gaacaaaaac gatatcgatt ggactgattt cctttttctc gcccccgatg acatctagat
    14821 agacattgta aagggttgtt gcatcttcag gatgtagatc agatgctgtg ctgcttggca
    14881 gaacaggttc tacccatttt ttgatgtacg ccccgttata atccaagtaa ctgttttcaa
    14941 aattccgttc atttccccaa agctgaacgg tttgagctgg aacgtttcta tcttcttcgc
    15001 ctgcagttga tccattatta gtagcatagt cgtaatttcg ccagttcgct cccccgtttg
    15061 tataatcact atcatcgatc aagttctctc cgtcatatgg cgagcctttg tctccttgat
    15121 agcgttcatt gctttgtgtc caatttccta acacttttgt atagtcattc gttgtaaact
    15181 tcgggtagcg atgctgttcg ttttcaactt ctccgctagg atagatatat tcataggggt
    15241 cttgcgtagc tgttggccca agacgctcca aaataccgtt gaataactgg cgttgaatgc
    15301 gctggagtgc ttgaccgctg ggtacgattg gttcgtccag cttttccatc tcattttctt
    15361 cgctacgttg aatttcagcg gaatcttctg tatcagtttc attttcttgt aattcttggt
    15421 tatctattct ttcatcaacc accacttgaa gaggtagtta cccttcgttc acatcgggga
    15481 tcttttctgt ttcaaaaatc aatgtgccgg tttctgcttc ttttgaataa acttttccga
    15541 cataccattc ttgaccatcg atcgtctcga cttttaggtc ttctccatct tcatcatagg
    15601 aggatagacc tgttccacga acgtttttta cggtaccaat cccggcggct gccgcatcga
    15661 ttgctaaacg tattctacct tcattggcac tttccttttt ttcaaaagcc agatgccatt
    15721 caagggtttc ttctttttca atatacttcc cttcaatttt tgcatagtcc tcatctaaga
    15781 atacctcatc ctcctttgtt tctgttgact cagcagctac atccagggtc gtcatatgat
    15841 agactgactg gaaatatggt ccaaatagca aactgacagt tactaactgc aaaagcttca
    15901 attttaaccc tttcacatcc ttatactcct ttcaaaaata tttgtcttct ttcacaacaa
    15961 tcaacaaaac aatgcccatc taattataat ttaatttaat tttaatttta aatcaaatga
    16021 tatccttttt agttaaaaaa caccaattat acaacattta ttattaaaat taaattataa
    16081 aattttataa cgttctcatt taacaaaact taagttatta agacaaatga ataaacaact
    16141 acgctttcct cgaaacaaaa aaataaagca caaatgcgca tttacgcact catgctttat
    16201 tcgtacaatt aattcagata acggcagcgc ataggatgcc aataacactt cctaaaatag
    16261 ctcctcctaa aatgtcagta ggataatgta aaagtaaaaa aatcctcgaa taagcgatca
    16321 aacaagcaaa taaaaaggct aatattcctg caactggact taattcgaac aacgcagcta
    16381 ctgataaaaa ggctagcgct gtatgtcctg aaggaaaaga agaagtcttc ggtttacttg
    16441 tgtaaaggac aagccgacga tttttttcat aaggtctttt ccgtcttgtc gtttttttga
    16501 taaaaagcaa accaacaaaa aaatagatca aactgccgat aagaatggct agaccatatt
    16561 ctctagtatc aggtatcaag actaaaacag cagcaaggag caaccaaata aaaccaccat
    16621 tagagatatt actgataaat ttcaaaaaat tgatttttcg actatccgtt ttccgttgct
    16681 tggcgaactt gttgataata ctatcatcga ttttagcaat caaacgcaac atgttattcc
    16741 tcctttttaa gaaccttttc ttgcgtacga tggataaaaa gcaggacttg aaaataaaac
    16801 aagaaactga aacctaataa agcaaaatag attggtcctg caaaccagaa tgcgacaaga
    16861 aggatcaacg tgcctgccaa atagaaaagc gcgcttttga aatcattaaa aaacaagaaa
    16921 aatgcagtaa tccaagaagc ttctttttgt tccagttgaa gcaagatttt gtaactaaag
    16981 agaagcgcgc ttaatagaag caaaaacaac gtagtataca tcaatgtata gccaattccc
    17041 ccaccccaat agcggaaaat ctgataatcg atcaatagaa gaagaaaata aacacttgct
    17101 aaactatctt gctttccata aagagagaag ttctcacgaa actttttcca gaatagtgaa
    17161 ccgagctttt tctcttcatt ttttttgtaa tgataaatca tatacagaac tgttcgactt
    17221 gcagttccta atgtgaaaac aggcaagacg cacaggaacc atagtagctg taaatggata
    17281 agacgtggaa tccattcaat gatttctaag aaataatcat tggctttttt accaatcgat
    17341 cgattcatca tccttttgaa cctcctgtca aatccatccc ttcaatgaaa taacgttgtg
    17401 caaaaaagaa cagcaaaatc gtcgggatca agacaagtgt tgctcctgcc atcagataat
    17461 tccattgtgt cgttgcttgg ttctgaaaaa cttgcaagcc aatctgtaac gtgtattttt
    17521 cttgatcttg gatatataac agaggaccta agaaatcatt ccaagctgcg ttgaaggaat
    17581 tgatcgcaat ggtaatcaag gcaggtttcg tcaatggaag catcaaatga ctccaaatat
    17641 acaaatgatt cgctccgtcg atttcagcag cttcgatcaa ttcattattg atcgataagt
    17701 aaaattgacg catcagaaat atattgaacg cattgccgaa gaacgatgga acgatcaggg
    17761 gcaaataagt acctacccag ccgatcttgg agaataatac atattgaggg atcatcgtta
    17821 caaaccccgg gatcatcatc gtagaaagaa ccaaagcaaa catcagcttt ttcccaggaa
    17881 aatcaagctt cgcaaatcca taagcaataa aagaatttga aaggacatta ccgatcacta
    17941 ctagcacagt gatgaataat gtatttcttg catagcgcca aaaaggaaag gcggcaatcg
    18001 tatccagata gttttcccat acgatttttt ctgggaaaaa ggtcggagga taacgaacga
    18061 tttcttccat tggtttcaat gaagtaaaca ccatccaaag caatggaatg atcaaaatga
    18121 ttcctattac tgtcatgagg acataactta gtattttttt tgtttgccga ttcacactgg
    18181 tctttttgaa ataatccatc atttgccgtc acctccagaa taatagaccc acttaggtgc
    18241 aagcttcaaa ttgacaaacg tcagaaccaa cacgatcaga aacaggatca ttgacatagc
    18301 catcgcataa cccatatcaa aagctacgaa cgccttgttc cacatatgca gattataaaa
    18361 aagcaaagaa tttgcaggtc cgcctgttcc atttttcgtc atgacataag cttcttgaaa
    18421 aatttggaaa gaaccgatcg tagaggtgat cacatcgtaa aaaataatag gagtgattaa
    18481 tggcaaagta atacttttga actttcccca aacgcctgct ccatcgattt ctgctgattc
    18541 atataaagat ctaggaacat tttgtaatgt agctaagtaa agtagcattg ctcctccaga
    18601 actccatatt ttcatcaaaa tcaacgcagg tttcgtccat tgtggatcaa acagccaagc
    18661 tggtccaggg atatggaacc agcccagaaa tgtgttgatc aatcctgcag atggagaaag
    18721 cagctgcatc cataagatgt agactgctac tcctgataag actgccggta aatagaaagc
    18781 tgtacggaat acactgattc ctttgatttt ttgattgagt actgtggcta aaaacacact
    18841 gaaaatcgtc gtcagcggta cattgaagat gacgaaataa acggtgttgt ataacgattt
    18901 ccaaaataaa tcatcgtgaa cgaacattct tttgaaattt gctagaccaa tgaaattcat
    18961 cttggatgtc aaattataat cggtgaaact accaataact gaaaaaagca taggccctag
    19021 cataaatacc aagaacccga taataaaagg cgagataaat aaataggccc atcttgcttc
    19081 ttttttcttt cggatagata aacgcttcaa attttcttgc ctcctctgta cctagacagt
    19141 caaaaatgga ttattgattt tgcttgacta agttttctac tgctttttgt gcatctgcca
    19201 atccttcttt tggtgatttt gttcctaaaa gaatctggtc aatctgttca ttcactaatg
    19261 tcgtgtaatc cggagcatct aaaggaactg gtgtgatcac cgtattttta aagttttcgt
    19321 ccgccatttg atagatcatt tttcctttat ccgttaggtt gtcattattc actaaattct
    19381 cattggctgt cttgctcgcc atgatatcaa aacttttttc gccgaatttt tcttgtactt
    19441 ctggagaaga aagatatttg atgaattcat aagaggcctc aggatctttt gctccgtatg
    19501 gtacttccaa gacgaatccg ccaccccacg accaatggcc tgaaccttct tctttttctg
    19561 ggagctgcat cacgccaaaa tcaaaatcat ccggtgcatt ttccatcaaa ctagagtaat
    19621 aattgatatt ttgggcacgc atggctacta atccggaaat aaatggatca gatacaccag
    19681 acccaaattc ggcttctaat ttattgatcg tatttttccc ataataatct tgccagtctt
    19741 ggatccactc caaggcttcc actttatttt tagtatcaat cttgactttt tcatctttgt
    19801 caaaccaact agtcccgtta tctgcgttta gcgcccatac atcagcccct aaattccata
    19861 atggataaaa accgatgcgt gtaaattctt ttccttcttt tttatctagt ttacgtgctg
    19921 tttcttctaa ttcatcccaa gttgtcggta gatcttgttc actgattcca gcttctttaa
    19981 ataacttttt attataaaaa atgacttgtg tatctgtatt gaatgggatc gcataaggat
    20041 caccttcata ttctactgta tcccaaagct gcggataaaa atccttagaa gtgtcttttt
    20101 ctacatattt ggagagatta gttgcttgct gtgcttctgc tctttgggca acggaattta
    20161 tgtcctgtac aataacatcg ggtgcatttc cagctgttat tgcagataaa gatttagtcc
    20221 agatgtcacc ccatggctga tacttataat ttacatggat ctcgttttgt gattgattga
    20281 aatcctcaat gatttcttcg atagcttctt ttcgtgcacc ggatccccaa aaggaccaga
    20341 aatcaatatt ttttcttcca tcacttgttt tttcagaaga atttgctgca cttgaactgg
    20401 catcgcttgc attacttgat ccgcatcctc ctaataaaaa caatgctgaa cttgccagca
    20461 accctgtaaa caataatttt ttcatatttt acctccaaat tttaatgtaa ccgatgccgg
    20521 ttttaatata acgatatcat tttgttctga aaataacaat ttataaggta tgattctaaa
    20581 aaaattatta atgataccaa tactttatat aattcgcgag cgctttcttt gaatttttta
    20641 atctttcgta gcagaatgag aatgtattaa aaatagatta ggaggaattt tgatgtttag
    20701 acaccagaaa gaattgcagt ttgaagcaaa accagatcgt ccgaatccat taatcgcgaa
    20761 atatctgcag gagctgatcg gcggccaata tggcgagatg agtgtagcta tgcagtacct
    20821 gttccaaggc tggagctgcc gaggagaaga aaaatataaa gatatgctga tggacattgc
    20881 aacagaagaa atcggccacg tggaaatgtt ggcgacaatg gttgctcgtt tattagaggg
    20941 tgcgcctgtt gaagatcaag aagcagcgat gcaaaaagat ccaacaatcg gtgccattat
    21001 ctctggaatg aatccacagc acgcgatcgt agctggctta ggacctcgtc ctgctgacag
    21061 cgtgggcaat ccatggagcg gtgcctatat cattgcgagt ggcaacttgt tagcagactt
    21121 tagagctaat ttaaatgccg aatcacaagg aagacttcaa gtagcacgta tttacgaaat
    21181 gatcgatgat cgtggcgtaa aagatatgct gtctgttctc cttgcaagag atagctatca
    21241 tcaaaatcta tgggaatgtg cagtgaaaga attagaagaa aaagaaggtt caatcttagt
    21301 cccaagtact ttcccgcgtg acaaagaacg aaaagacatt gcttatgact tctataactt
    21361 ctcagaggga gaccaaagta gtgaaggttc ttgggctagt ggcaaagcac tggatggcga
    21421 aggcgaatat caatggttga aagaacctaa gatcgaaggc gctgcaccaa aattagaacc
    21481 agtaacacca aaaatgtatg ggacacctcc attcaagaaa taaatatcta cccgtagaaa
    21541 cacccgtttt ttgttccaca cgctttgtga gcaaaactga ctaaagtcat taatcataac
    21601 cacccttcaa aagggtggtt ttctctagag ctataagctc aaatcaccgg ccagcgccta
    21661 aagacgctgg ctttcatatt ttatgttcaa gccatattgc ctttgccagt tttgcccacc
    21721 tcttaaaagg tttatgtact actccttagc ccttaaaagg atcgtcttac tctcgtacac
    21781 tcagcttatc taacgcacta tcatgttttt cttgttcttg aatgtacttt ttgatggtcg
    21841 cttcattttg tcctactttt gtcacatagt atccttccac ccaaaagtgt cgatacccaa
    21901 atttatattt tagatttgca caatctcttg atgatctcct gaatattggc tcgatattga
    21961 ttataaatta tttttcttct atactttggt gtgaatacaa tgtggtattt acacatctac
    22021 tttgtacggg ctaaactatt tccctttatt gctccacccg catagcaagt ggttttgtat
    22081 ttcaatcgct cggcgcgctc aattaggtct aaagacaata aatctaaaaa cccgctgctt
    22141 cactgacaga aacaacgggt tttcagaaaa aaatgaaatg aaaaagatct cttacggcaa
    22201 tctattttat ttttttgatt ttttataaat ggaaaatgct tcaagaagtc caagaaataa
    22261 agccgtataa aaacaagaac ctatgaaatc tttatttatt agatattcaa cagaaatccc
    22321 gataacacta gccaacaata tatttatcag aagtgtaaaa taaggatgct ttttatagaa
    22381 tagaactagt gttgttttca tagactctcc tttcttcata tttccaatta atcacaaatt
    22441 cacggcatta ctagaaaaat taaaggggcg cagaagtgga aaaatactct tcgactttcc
    22501 ctacaaacca ggccatcttg tgtttaataa ctataccaaa tctaaggtac ctctaaatct
    22561 aaattccatt tgtggcggtg acctccaatt tttaactctt ctatctccca tccagtatac
    22621 ataaccttga tacttcgacc acttatatat cgaacacaca aatacctatc cattgcagga
    22681 gtactaccta acttagttgc tacttgcatc taaataacag ctgaaaagat aggacttact
    22741 cttagtaaag tatctgaact attaattttt aaactatcat ttttatcctc aactacatgc
    22801 acatctgttg caacttcact ttctgtctca tccagataaa tgattaagga atcgggaatt
    22861 gcaatatctt cagctgacgc tggaatagtt gagctaaatt agtcatcata tctttattat
    22921 aaaataacca acagcaaaaa atacaatgaa aaacaaactt ggaactaatg tatcattaat
    22981 aaatgttgaa aaattcagca actcattact gtatgatttt agcagcccaa ccaacatata
    23041 ccctataaaa gctaataaga tggttaggaa tcctttagaa tttttactca ttcatagaca
    23101 cttccttaaa taacttttat tatagaaggt attgtaaata ataatattga caaaaagtga
    23161 ctcaaaataa aaaaaacctt acattatact ggaatgaact gtattgatag tgtacctaaa
    23221 agctctactg acataagatc gtgtaatcgg taaagtaatt ttattaatta tacgggatgt
    23281 aatcaattag agaataaact aatcataaaa ggtactttta cattcataat tgtcgctttg
    23341 agattctact ttggttcact atctgaccca attgcacatt ttcgatcatt acaagtattg
    23401 gtgtcgttag aacaactaaa taaaaactag cggtagattt ttcagaatct atgctaattt
    23461 ctgtatggat gttccagtga tggcaaattt ctcttttcat tgtttttctt gtcgcatgat
    23521 atgccttttt gtgttattca gttaaactat agaaattctt tcctagacag atcttgatcc
    23581 caaattttac gtttttgagc atcgatatag tttaaaatga cattactcat atctaaagag
    23641 tttagatttt ttaggactaa aactgtcagt tgttcttttt cttctttctg ttaaagtatt
    23701 gtcgcgactt ttcgtatacg ttaagatatg tcgtgaaaaa acaagttttg tgacacaaaa
    23761 aaacgaatga cttgaggaaa tcacctcaat cattcgttta aaatgctata tattctttag
    23821 tttaagatac ggaaattaat gccatcgacc acactagtag aatgaacgac atttacttgg
    23881 ccttttttta atttcgttat gtttagcata taaaaatatt atagagttta cttacaatgc
    23941 ttaaaacata tactgtataa tctgatcaat tttagccatg tcttgcaatg gtaagttttc
    24001 tatttttttg agttttcgtt ccttaaaatc aagagatttt aattgtgtaa taattacttg
    24061 tccttttata tctagctctt caggtaatga gtaacgtgtc ggtaaattct ttatagtgga
    24121 agtaattgga catatgaccg aaaacattgt tttacggtta aattcataac gagagacgac
    24181 tagtcctggt cgtctttttt gaatttcttt tcctacggag ggatcaaaat caatccatac
    24241 aatatcacct tttttaggaa tataaattct ttcttctgac actataaaat ttctctccct
    24301 tcaggagtta aatcttccca ttcgtctttc tcataatact cggcctcttc cccaccacta
    24361 aatggatctt caatttttgg aactaacgta attgttccat catcagaata cacaacgata
    24421 tattcttggt tttctgaagg tttctttccg ttatcagaag gtaaagttac cactacagaa
    24481 cttccttgta atctagattt tgtaacaagc attatcatca ctcccttaat aaaagtatac
    24541 tatataacac taagtaacgc aaaattcccc tttgtaaact atctagaaaa ttgttttgtt
    24601 taaagtatat cttattggat ataaatagaa ataaattgta gccagttcat tttttcttta
    24661 actaaaaaaa taatccaaga aacattgaac ctatggatcc aaaagctacc caaatactat
    24721 agctaacccc ccgctacctt caattttgca gataaaacgc tttgggagaa aatttcaaag
    24781 acaacaggcc atcctatcat gcccgattat aaacaaaaag ctggctattc cttttgctct
    24841 gacaaatttc aattgggaaa gttcacgaaa ctagcaggtg aagaagtttc aactgttcgg
    24901 atcaaagaat gcccgcttca aatagaaaca ttggttcaac gaatttcaac tagacaagac
    24961 tttgctattg tagaacgtga gatcgtagct atttttgtag aagaagggat tttacatgat
    25021 ccaactcata tcaatgtgga taaatggcaa cctcttatct ataaattcag agaatataca
    25081 actgccaacc agtcgttaac tttgaatttt agattccaag aattcaaaga gtcataatga
    25141 taaacatcgt taggtataaa taaaaaagac tcgcagcacg agtaaaaaac aaatagaagc
    25201 tatacattag aaaggtcgac tgtgacccta tagatgcagt atatgcagct tatgagcatt
    25261 tcttctgttc tctttgtttt tgggatctgt gctgaagtct ttttcgtttt ttgccgctct
    25321 ttctttgaaa aatcgattat gttatacctt ctccattact aattcaggca tctgctgagt
    25381 aatgattttt cgcgcaaaag aaatatctgt tacccaaggt tcgatttgtt cttcagtcaa
    25441 gacaagcggc attcggtcat ggattggtgc gactgtgcgg ttaggttcag tagtcattat
    25501 gattgattct gccatttttt catcctgatg gctacgataa aaaccgccaa tatacactat
    25561 tttttcctta tttgaaaaca taaatttgtc tttttcttca ttccactcat tgggaaaaca
    25621 caacgatttt gcaaaaatgg ttgatgaaag gtcttttttt cttctactgt ctctgcacgg
    25681 gcattaatca tcaattgtcc ttttttaaat ccggtaaatc cccacttcat gatttccgga
    25741 gtgaggatgt tttcttcctc ttttcttaac gtcacaacaa gatttgacgg aaaaacttct
    25801 ccagctgcta attctgctgc ctgcttcggt tgtttcgtct gggcttctcg ataataattc
    25861 tgaaggagct ctgactctag atcaaaaaaa taacgaccac acatcctaat ccctcccaat
    25921 ctttttttct atcatacact gcaacaagaa gttcgcacca acaaaacgct ttcaattttt
    25981 gtagaactaa aaaagttgtg acaagtgaca aactctccag tgaatggtat tctcctgcca
    26041 actcctcggt cacaagtcac aatattcaac aaacatgaga agctgctttt tgaaattgtt
    26101 ccttgtgact cggagtgaaa cggcaggctt acgacctctg ggtaaacggt gttcaaaagc
    26161 cagtttctcg gtattaagcc aaatttatgc aaaaatgtag aaagctattt tcacaaaatt
    26221 tttcttaata ctcgaaacta agcgactttt tcacaacctc ttccttaaac ggtgttcaaa
    26281 agcttgcatc tgcggtaata agcccaacca aacgaaaaat atgagcagct atttttattt
    26341 ggctgttctt attacttgat gcagggcagc tttttcacaa cctctccact aaacggtgtt
    26401 caatcagcta accttcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttgcc
    26461 gtttgtttct ctaatactca ggtcaaagcg ctgatttcac aacctctaat acacggtgtt
    26521 ccagaagtag cttcttcgaa aaataagccg aaatttcaca aaaatttgag aagcaatttt
    26581 cgtaaattcc ttcttatttc ttgaagctga ccacttctgt cacaacctct aattattaaa
    26641 gaaccttttg cgaagttaac aatctttctt tgatcaattg aaaattctgc ctaagtagtg
    26701 atagatcctg tgtgactttc aacaataaga tacttccctg gatttcagca atcaacgctt
    26761 tggcttgacg gtctgcttct tcatcggaca gtttttcttc agaaagtgcc aggatatttt
    26821 gtttcgtata cttgacccat tgattgacta attctagtag caacagacgg tattcttcat
    26881 ccactgtact caactcaata atcaaattac ctacaggaca gccatgataa gtgatctgtg
    26941 tctcatgatc agcgaaaatc cagtccaaca tttcttctaa tgcttcttct ggctgttttc
    27001 cagcatttaa gatgtcttcg aacaattctg tctgccatac gtccatatgc gcatggatca
    27061 ccgctagaca aacttctttt tttgaagaaa agtaataata aaattgacct tttcctgtat
    27121 cagaagctgc tagaatatct cggattgacg tttcatgata gcctttttta taaataagat
    27181 ctttggtcgc ttccaagatc ttttcctttg ttttcaatga tattctcctt tttcatttct
    27241 catagtccta tattatacag taaattcatc attttttctt cttaatcgtt taaaaaagac
    27301 tgtgccaaat tatctgacac agccctcact ataaaactgt tctcatatag ctagatgttc
    27361 attgattcaa gaactgcgag gacaaaagca attcctatct tatgatagtt gctctaatac
    27421 ttcctctgtt gtcatcactt gatctgcaat aaagccaaag ttcgtcaacg ctgcatccat
    27481 tgcttcttgg ccaggagcac caattgcatc tgtcgctacc acaacattga atccactctc
    27541 taccaattca cgcatatggg aatcgctaca caagtttccg ttcattccac caagaattac
    27601 tgtgtcgatt ccattttttc tcaattggag cgccaaatca ttgctttctg gtccaaagat
    27661 tttatgagga gagctgatga tcgtattttc atccaaataa ggtttcaatt cttcgataaa
    27721 atcggctcct gaaccttctt ccactgattc atattgactt tttctagcaa acatctgctg
    27781 ctcaagcatc atatgttctc ctgcaccgcc aaattgccat ttatggtcat gtgggtaaaa
    27841 ataatgagga gaaataaaga gtttgtatcc tttttctttt gcttgtttta ccatttcaat
    27901 catattttcg atcgtattgt atttttctaa gatatctttt gtcaaaccaa agccaccgcc
    27961 tgctggtttc aagaactcga cttgcgggtc agtgagaact actgctgtat ttttattatt
    28021 gaacatggtg gattctccat tcgttattta ttttaataca tcatttagag cttcactcat
    28081 tgtcggatga gaatagattt gatctctcaa taacgtataa ggaagttttc cattcatagc
    28141 tagcgaaatc aagttgatga cttcatgaga atcttccgca tagatacttg cccctagaat
    28201 caagtcagtt tcagggtcga ctaaaacttt gaatacacct ttaggatctt ctaatacttg
    28261 tgctttaggg acaccgcttg tcatatactt gaataatttg taattgacgc cttgtgcttt
    28321 ggcttgtttt tctgttaaac ctacattgga taaagtcgga gtgataaata cactgtaagg
    28381 cacagctttc cggttattcg ttgttcgttt attctcgccc ttcaactgat ccataatgat
    28441 tcgataatca tctagagaga tataagtgaa ctgcaatccg cctttgacgt ctccaatcgc
    28501 ccaaatgttg tctgcatctg tacgaaggta ttcatccaca gcgattgctc cgcgatctgt
    28561 tagtttaaca tctgtatttt ctaatccaag tgatgctgta cttggttttc ttccagttgc
    28621 agccaaaact tttgacgctt ggattgttac ttcttggcca tcttctgtaa aggtgacggc
    28681 agctgttgat tcttggtctg ctacttgatc tacagataca cctagatgga attcgattcc
    28741 cgcatttgtc atgtcttcta aaatcatttg cgcgatatct tcatcttcac gtggaagaaa
    28801 ttcagaatgg gcatcaagaa cgacaacttt agatccgtat tcattgaaca ttgatgcaaa
    28861 ttccaagcca atatatccag ccccgatgat cactaatttt tccggtaatt gttcctgatc
    28921 catcgcttgc gtagaatcaa tcaagtagcg acttgtattc aatcctttga ttggtaaaat
    28981 gattggttca gaaccagtat tgatgaaaat ccgttcgcct tcaacaatca ctttttcacc
    29041 attattcgtc acttcgattt gatggttaga aagaaaacgt gctgtaccgt ccatcactgt
    29101 cccagttgcc tcatcgctga tcatatgata atttttggcg cgaagcatgc ccgtcaattt
    29161 ttctttccga gcaacagcct ctgtaaagtc gattcctctt tctccattga aaatcaatga
    29221 tttagaagga atacagccga tgttgataca tgttccgcca tacatacgtg ttgacttttc
    29281 aacgactaaa accgattcac cttttgaagc taacgccttc gctaaagtct taccgccctt
    29341 tccaaaaccg atcacaatat tttgatattt ttccatcatt tttccctcgc ttctttttta
    29401 cctaccgatt ggtacaaaaa tatgataacc gataattgtc tattctccaa atcatctgct
    29461 ttatttgtca aaaaaaacca gacaaaaagc ggtcctttca cgtttttagt ctggttcgat
    29521 ttcctttatt cttctaaaca atcgttactt ctacatcgat atttcctcta gttgctttgg
    29581 agtaagggca gaattcatgc gcatcttctg caattttttg ggcttcttct tcgctgatgc
    29641 catcgatatg cacttctaat actacaccga tctgatagcc gccatcatct aaattataaa
    29701 gagagacacg tgcttttact gtggactctg ctgtcattcc tgcttctttg atcatatgtt
    29761 gtaccgcccc attgaaacaa gaagcataac ctgctgcaaa taattgttct ggatttgttc
    29821 cttctgcatg gattcctgga ggagtgattt tcatatgcat cgagccattt ggtgcctcga
    29881 cttctccatt gcgcccgcca tggttgatca ttgctgtttc gtatgctttt ttcattgtac
    29941 tgctcctttc gattgaccat ttgctacttg gctataatta tagtgtatga caagtaaggc
    30001 gctttctaca aaaattctgc ttattcgaat accagaatgc cgtcttctac tatttttcca
    30061 aaaaacaaaa aaatactact cgtgaacaac agcgtcatat ttgttccaaa ataaatagca
    30121 atcttttcta cataatcttt tatatgattg attttaagat acatatatac cagaaagttg
    30181 accccataaa ccaatactgt taaaaaaata accatattcg ttaccatttt ttcctccttt
    30241 tgctggtctc cctaccagca ctcgatttaa ccataccact ttttttgccg tccaagcaac
    30301 tagcctttca aaaagactgg tttattctgc tgttaatgat tcaagatcag aaaaatgtcc
    30361 gaataatttt gctaatttta ctaacgccaa cttgttcttt ccgaattcat cattttctat
    30421 ctgtaatact agtaacggct catgtaagct taaacggatc aaaaaccagc cgtttccgta
    30481 tggctcttct agatcatatc gaataccttc ttcattttcc gggtcgaagt tcatcccttt
    30541 ttcttcttcc aacagtcgct tcatttcttc taatatcttg tttccttgtt cgcgtggttc
    30601 atcgctgaac aattttaatc ggatttcttg tacttctacg ggctgtttca actctttgat
    30661 ttgttcatct aatgtgatac cttttctttt taattctggc aaaagcatca ggatctttgc
    30721 gatgacatat gcaccatcat ccagaaaata gttttccttg aatgcagcgt gtccgcttgt
    30781 ttcgatggct agctgtgtat ctttcccaag acggttaagt tctaatgctt tattgattac
    30841 atttcgatag ccggaaatat aacgaacttg gatgcctcct ttttcttcaa tgaatctttg
    30901 tagatgagaa gaagtagggg aattcgtcac gattcttgtt cctggatgct cttttaatac
    30961 gattgtactt aatactgcga tcaaattatt tcgattgatc actgttccag aagcactgac
    31021 aactgcagaa cgatccacat ctgtatcgaa aatgatccca agatctgctt catttgctaa
    31081 aacagcctgc ttgatacttt ccatcgcttc tttattatca ggatttggga tatgattagg
    31141 aaatcggcca tctggttcca aaaattggga acctgttgaa tccgcaccta agctattcaa
    31201 tactttttca gcaaagaatc caccagcacc atttccggca tcaacaatga ttttccaacc
    31261 atttagtggt ttgctttcta gtgttccaat ccccttttta atttttgtga ctaaatcttg
    31321 cgcataaggt gtcaaaaggt ctgctttttc tacgcttcca gtttgttcgc tttttatttt
    31381 ttgctgctgt gataggataa aagcaatatc ttctttttct gctcctcctt ctgaggtaaa
    31441 gaattttatt ccattataat aatagggaag atggctagca gtcagcataa ccgcagcatc
    31501 gcacgagaac tgttcaaatt gagtggacat aaacatagca ggcgtagtag ctaattcgaa
    31561 atcgatgaca tgtatccctt gttctttcag actttggatc aacgcctctt tcagtgctgg
    31621 tccgcttatc ctactgtcat gaccaatccc aatcgtccat tttttatttg gatcggttga
    31681 tttcttcttt ttctttatcc agtttgctag tccccagccg atctttttta ccatgtctgt
    31741 cgtcaagttt acttcatatc cttcaactgg taatgcgatt cctcgaatat ccgatccatt
    31801 ttgcagcgct ttcatatctt tcatataaaa gtcctcctca tttattccct cattttttcc
    31861 agcttttctg caaatcgctg tgcttcttct tctgagcggc aaataataat gaatgtatct
    31921 acaccggcca tcgttccgac aacttcaggg taagccactt catctagcca attcgttacc
    31981 acatcggcac catttcgttc agtcaatacg ataaccatga actgaacaga ctggatacgc
    32041 aaaacctcgc gtctaattgc tgtacgcaaa cgttcttcat ttaaagaaac agatggctgg
    32101 ttaaataatg tatagcgtac tattttgttt tcattttgac tttttactaa cttcatttct
    32161 cgaatgtctc gagaaatcgt tgcttgagtc acatcggcgc ctgcttcatg cagccgcgca
    32221 agcagctctt cctgtgtccc aataggttgt tctgtaatga tctggcggat cagtgcttgt
    32281 cgctgtttct ttttcatatt agacacctct caatgttgat tatagcaaaa gataagtaat
    32341 atttcttcat attttggtat tttttacttt tattttttgt tttcattcag gttgctaacc
    32401 tttttctatt ttaacacgca aaatcgtctt cattttttca ggtgctgatt ttcttggatc
    32461 gctgatgtaa atctctttgt gttctttaga agctctttca tagccttctt ttgcgatgaa
    32521 tgcttctaat ttctcaaacg ttgctggttc ttcggcatag ggcccgacgt gtaagatttg
    32581 ggcacaaaga ccttcttcca tctttttgaa tactacttgt tctttcaagt cttccggaag
    32641 tttgctagaa cgctgaatgg cttcttgtgc tatcgcttct gtaacaaagt caggctgtcg
    32701 gatcatcaat tgataagaaa aatgttcttt tttcatcact ggttcatgca aatacttttc
    32761 ttgcagtccc cattgtcctt ccagtggata gacagtatac atctgataat caggaatcag
    32821 ccaatttttt ttaggcgaca tgcgtattgc atagctgact gcatatagac aggctactct
    32881 tcgtttaaag tcttcctgat tcgggtcgcc gatccctctg atgctaaaga atgatttttt
    32941 aggaacctct agtatttgcg ggcttttttt catactatag ctcttgtctt tacgccattc
    33001 aattttttcc atttttcttc ctccgcgaaa ttccatttag ttatttatta tcatacctct
    33061 ttttgagtga cttggctaat cgtgttgaca ctatttttca gtttgtgcta gaataagtga
    33121 agtaaataaa tcgtacagat aacacgtttc ggcgtgtcga gagagaggcg gtttctattt
    33181 ttataataga aatcactctc tttttttacg aaatttttta gaggtgatgt aaatgacaaa
    33241 acaaaaacag ctgcttttag tacctgcagt aattgcaaca gggatgatgt cttttgcggg
    33301 cgtattgatc gagacggcca tgaatgtaac tttcccaact cttatcagac agtttgattt
    33361 aacgactgca caagtccaat gggtaacaac gatttatctt ttgatgattt cgatcattgt
    33421 tccgctgtct acttatttga atcgcaattt tagtctcaaa aaactctttt tagcttcaaa
    33481 tctgcttttc ttggcaggta taatgatcga tttcttctct cctaccttca tggtcctatt
    33541 gtttggtcga ttgctccaag gtgcagcgac aggtatcgct cttccgttga tgttccatat
    33601 tatcttgaca tttgcccccc tcaatcgacg aggcgcgatg atgggtgtcg gtactttgac
    33661 aacggccatt gctccagcaa ttggccccac ttatggaggc attatgactt cacattttac
    33721 atggaatcat atcttcctgt ttcttgtgcc cgttttgttt ctttctttga ttatcggctg
    33781 gtttgctatt cccgagatgg cagtacaaaa aagtggttat ttggattgga taagcgtttt
    33841 aggaatttgt cttttgttta gtggaagtct aacatttttg agtacgttgg gaacagtttc
    33901 cagctggatt gctttaatca tcggcggtat tggctggttc cttttttact atcgaagtaa
    33961 aaaagtggag catccactga tccgactgtc tattctttca aataaaacat tccgcttgtt
    34021 tttgattggc ttcttagttt atcagttttt attacttggt gtatcttttg tcttgccgaa
    34081 tttccttcag atcgttcaag gaagtagtcc ttttgtcgct ggattagcga tgcttcccgg
    34141 cgcagcggtt ggtgctttgc tttctccttt ttccgggaaa atgctggatc aatatggtcc
    34201 gaagaagcca atttttgctg ggctgattct ttctttgatt ggttggctag cattattcct
    34261 actcatagga cacgcttcag tgggtgtatt gattgcttgt catgtgtttt atatgatcgg
    34321 tatcggatta tcttacagca atatgatgac caccggaatg aatgcactga atgaagaact
    34381 acaaggagac gggaacgcaa tgttcaatac cttgcagcag ttttctggcg ctgtggctac
    34441 ttcattagta gcggtcatta tcaattacgt ccagcatcat acttcccata actatgaagt
    34501 gtctactaca ttaggatcaa aagcagcatt aggcgtcttg ttgctgttgc ttctcgtaag
    34561 ctttgctcga ttcgcctatt atctgttctt tgctaaaaaa gcgtagattc catatacggc
    34621 aggtgttgca tctgccgttt ttttgtgtga aaatggttgt ttgtaaaagg aggctttttt
    34681 atggaaaaaa ttgccattat cggtggcggg atcattggta tgaccctagc cagttactta
    34741 gatacatcaa aattcaatgt tgctttattt gatgaaggga caggacaggc aactaaagct
    34801 agcgctggga ttatctcccc ttggttgtcg aaacgcagaa acaaacaatg gtatcgtctg
    34861 gctaaagacg gcgctgcttt tttccctaaa cttataaaag atttccaact tgatcaaacg
    34921 atttacgcac aatcagggac acttttgctt cgacctgaaa aagatttagc tgaattggct
    34981 gttcttgccg agaaacgaaa agaagaagcg ccagaaattg gaaacatcga atggctttca
    35041 cctgaacaga catctcaagc acttccgtta ttgaaaccag cagtttcact gcgtatcagt
    35101 ggtggtggtc gtctggatgg aaaagcatat ttagaacatc ttggtcagcg tttagcacaa
    35161 aaacaaatgg agcagatcca ggcaaaagtc actttgcata agaagagcga ttcttggctc
    35221 atcaagggac cgtttggaga atacacagct gatcgtgtaa ttttgacacc tggcccggca
    35281 cttaagcctt tattacaaga attaggctat gctgcagata tacgtccgca aaaagggcag
    35341 ctcttagcat ttcagacatc ttataagatg agtcaagact ggcctgttgc tatgcttgac
    35401 ggagaagctg atttcattcc tttcatggat ggaaagatcc ttttaggtgc tacccatgaa
    35461 aacgatcaag gctgggattt ggctcctact agcgaagctt ataagggatt gactaagagt
    35521 acagaacagt tcttgactga tccagatcag ataaaaaact ggccatacga gttccgtgta
    35581 ggtacccgtg cttatacgtc agatttttcc ccatttttcg gcgtactgcc agatgatcca
    35641 agcttactgg ctgctagcgg tctaggctct tctggcttga ccacaggtcc ttatatcggc
    35701 tatctattag ccaacttctt aaatactggt cattggccta cggaagatta tcaaaaggac
    35761 atctccacct atattacgaa aaatccatca tagaaaaaca gctttttcaa gtaaggatcc
    35821 cgagcgatat tgcgcatgga ttacttcttg aaaaagctgt tattttagtt caatttctga
    35881 atcaaattct ccaaactttc ttttgcttca tctggcaaga gatcttttcc tatctgagct
    35941 tcaatgaatc gtaaacgaat atcaagtcgt tgtttcacca gatttttata ggacgtatcc
    36001 tcaaaagaaa caggaaaatc tggtataggt aaatagtgga tgtcttcaaa tggaccaaac
    36061 gacttgaatt ctgccgtttg ttgcacgatt ctttcaacga ttgacaatgt cgtttcaggt
    36121 ttgatttttt tatcatcgaa atatccagta ttcaggacat agcaggctgt ttgctgtttc
    36181 aaaaacaact ctcgaaaagc ttgatagtct tccctaagag gatagacacg gaaaggatta
    36241 gcaaatggtt caatgactag ctcatctagc tgtctttttg tagtgatatt ttccgcgtct
    36301 gatcgttttg ttgctaatgt tgcaccaaaa gacgctgcta aaactgggtc attgatcttg
    36361 ataattggcg gaagcgaatc atctttcatg atccaaaaaa cagcatcgat cttttcgcta
    36421 agatgatcga ctcggtcggg tgtcgcataa cgtgatttga ctgtccgccc atttccgttt
    36481 cgtatatctc ctgttactag gactttttct cctttacttg tacatgtcac gcccacattc
    36541 tgacaagtaa ggaaagaaga aatggccgga tcatcagacg gatagtcttg tgttttatca
    36601 aagtaagaag gttccaaggc agtagcaaaa ccattttttc gagaaataac gaaagcatcg
    36661 tcatgcaaga tcgaaacaga gtgaccttcc gtatgttttg ctaaggtaat cgttgatttt
    36721 ccagaaccgg acaacccaaa tacagccatc gtataggtct ggtcattact agcatattgt
    36781 ttcatcccac cgtggcaggc aataaagcca ttgcgatttc ccaatgccca agcaagcgtc
    36841 aaagtcgctt tttttaattc tccaaagtaa cgtaatccta gcacagccgc tgtattatgg
    36901 agagcatcaa acaaaatgag tccatttgga aatgtttcat gtgtccattc gggatcacaa
    36961 aagatataaa gatctccctc atcaaaggaa acagactttt gataagtctc taagatcttc
    37021 gaattcgctg gctgaaaatt cagcaaataa gaatacaaat tgttctcaaa tccttctgga
    37081 atcagcaaat gactttgcac agaaaattct tcagataggc caacgattac ttttgtatgg
    37141 taaaactggc gcttgcgact ttgatacaca gcttctctta aaattttctc gtatttgctt
    37201 tgttccttgt ctaagtcctc aaagatccgc cgagcacttg ctgttcttcc cacaatgctt
    37261 ccatcattga atactagtgt cctaacatca gctggtaaat ctagttcttc agcatgtgag
    37321 attgttaaat ctgtgatgat cgttcctgga ctcccttttg ctagttgata agctgtcttc
    37381 ctatcaaaaa cttcatgaac attattaccg taaaatgtcg tttctacaat cgatcgaata
    37441 ctggataaca gtggatttcc acttgtgatt tcgtttaatt cgagactctc ttttgtactc
    37501 atggctcctc ctcattccct aaacaaaaaa acgttttctt tattatacat tattcgagtt
    37561 tttatttgta ctgctgcgct gtgggaagca aacgagttat ttttcacaca aaaaaaccga
    37621 gaacttgaat aaacaagttt ctcggtttca tcattttcct tttatcggct tagtaccagc
    37681 cgtttgctaa ccagaatgtt ttagcagcat cccatgaacc ataacgagat gttacatatt
    37741 gttctgctac acgttcttga ttggcagctg aatagtcgcc gtttaagtat gaagcatcta
    37801 attgataacg gccgatgtaa cgtccgttag tagctgtgta tgaaccgcct gattcttttt
    37861 gtgcgatcca ttcttttgca gagcttgaag ttggcgctgt tgcagcagct ggggcagcag
    37921 gagctacttc aactgtttca acaggtgcaa cgtatgtatg ttcttgcgtt gctgtttcag
    37981 ttgtagatgc tgtattttct gttgttttgt tttctgttgt tgctgaagaa tcatttgaag
    38041 ttgggattgt taattgttca ccaacataaa tgcggttgat gtttgcgatc gaattttttt
    38101 cagcaattgc atcgatcatt gagttgtctc ctgcaaattt ttgtgagatc ttagataatg
    38161 aatcacctga ttttactgta taaacttcat cagcgtgagc atttgtagtt cctacaaaca
    38221 ttgcagtagc accagcagca aaagttgtac ctaaaacaat tttcttaaat gaattcatat
    38281 taaactcctt tttttctccg ttttttattc tttcgacgct attaacttta tcatttagaa
    38341 atatttcata ggtaaaagaa acatgacatt taatgacaaa ataacgaatt atttaatatt
    38401 tgtaacattt aaacaaatat ttttttgata caaaaccata aaagccttgt tgtataagca
    38461 aagtaatcgt ttttctatgt ttttttattt ttgaatgaaa aacgcagatt ctgtaacatt
    38521 cactgcaata atccataaaa aaaagcaaaa aaatttttga tttttatcaa attctcttaa
    38581 aaaaatgtaa aaaatacaaa aaaaccagta attgttacaa caattactgg acaaaaactt
    38641 tgaataatgt taactatttt tttattttaa ctttctccgc aataatttct gggcatgttc
    38701 caattcgttt ataacgactt cttctgtttc tttagctaat atttcatcta atacatcaag
    38761 ccatttttcc ggttcttttg ttcctagacg tccaatagcc caagctgctg ttcctctgat
    38821 gacagggcgg acatctgtta aacattctga aatctcaggc aatgccgttc gatcacctag
    38881 attagctaaa gcaatcaatg cgtttctctg caaaggtttc ttcccacgcc atgaaccagc
    38941 taaatgccca aattgctgtt tgaagtcttt attagacatc gaaagcattg gctttaattt
    39001 tggatatatt tcgtctactt ttggttccat ctcttcatga aaatgaaaat cttttccttg
    39061 attgtaaggg cagactaact ggcagatatc acatccataa atgacatttc gcattttttt
    39121 acgatattct tccggcatca tcccttttgt ctgagtttga taagacaaac atcgctgggc
    39181 attcattctt ccgtcaccaa gcaatgcttt tgtcggacaa gcagtcacgc agcgcataca
    39241 gtcaccgcaa ccaaattctc ctggtttatc aggctcaaat acaatattag taacgatctc
    39301 accaagatag acaaatgaac cgaactcttc agtgatcaac aatccgtttc gtccaataaa
    39361 tcctaaacca gctcgctgtg ctacagcgac atcgatcagt tctccagtat ctacttgcgg
    39421 agctagacgc cattcctctt ctttttgcca tttttctgct cttgtttgga tgaattcgat
    39481 caatcggttc aaacggtctc tgagtatatc atggtaatcg atcccccaag aagcacgagc
    39541 aaactgcccg cgtttttcat ccctaggcac ttcttcatgg atcctagtag gatacgcaag
    39601 tgcaatggaa atgatcgatt tcggctgatc aaatgtcatt tctggataaa gacgctcatc
    39661 gatatttgga tgttcaaagc cagaagtatg gccagctgct ttttgttctt ccaacgattc
    39721 ttttaatgaa tcaaaaggtt ccgccgtggt gaacccgatt ttgtcaattc ctaatcgttt
    39781 gctttcttgt atgatttctt cttttaatgt catggtcttc ctcgcttgct gttaacggct
    39841 gtataaccca taatatagtt tttctttttt cagctggaca aactggatct gctgatcggc
    39901 aatcttcttt tcttccatcc atttttttct tgcagcaaat acttcccaat aatttgttga
    39961 aattaatttt cttttgttat ctaatgcatt aaaaaaattc aatgaaactg gttttgtact
    40021 taacagttca tggagcctta cctcttccca tggcgaaaac tcagacagat cgcgggaata
    40081 caatacttct tcatagagat ttttttgctg tgtgtacgtg aatgtttgcg ggattttccc
    40141 aggcctagca atttctacta gacgattata aaacatattc attaatttgc tgttggcaat
    40201 aaattgactt ttataatagg ccgactggat ctttttgatt actccttctg ctttgatgac
    40261 tgaaaataat gcaggccatg ctttgacggt tatttcgtcg ttttgtttaa ctaatacgcc
    40321 aggtgtgaag ccgactggag aaaggaacac aaaataaccg ataccggtat tttcatctaa
    40381 aggctgaaat tcatcaaaca accatttgcc tatgtacagc tcttcatctg gttctgttgt
    40441 ctcattttga tttgctatga ataatttagc taattctgct tcaagaaatt gaaggtcttg
    40501 atccttgtcg gtattttcct gctggctgat caatcgaaag acttcttctt taatcgtata
    40561 tttatcttta cgtgtaaaat tcatagccac accttccttc cttactctaa ctataacgga
    40621 atttcttcaa aaaaggtatc tgtacgacga aaaacagcat aatttttttt catatctctt
    40681 ataaaaaatg caaggtctgc tcctcaagct agaccttgca cttttcagct ttcttttgtt
    40741 tgtgacaaac cttcatggat cgtttcaata ttccatttca tcatctgata gtaagaatct
    40801 ccttgttctc cttcttttgc tatggaatca gtgaacagtt tatcatagat tttcaaaccc
    40861 gtttcttttg ctacccgttc catgcttctt gagtctacac tggtttccac gaataaaacc
    40921 ggtacttctt ttgctcttat ctgatcaatg atcgctttca tttgatcagg cgtaccttga
    40981 ctttctgtat tgatctccca tatataagct gctggcaaat catatgctcg tgaaaaatac
    41041 ttgaatgccc cttcacttgt tactaataat tttttgttct cttcgataga agcaaaactt
    41101 tccttcgctt gtgtatctaa ttcttttagt ttttccacat atgcttctgc atttttttta
    41161 tagagtgtcg cattttctgc atctttttca gagaatatac gtgcgatttc ctccacatat
    41221 tttattccgt tagataggtc tagccaagca tggggatctg cttttgtatg ttcttcaccg
    41281 ctagttaaat aaagaggttc tacatttttg ctaactgcaa aataatcttt tccttcttct
    41341 tttttagccg tttccatcaa gttatcgaac cagctgttac ctgtttcaag attcaaaccg
    41401 ttgtataaaa taacatctgc atcgcttgcc tttttgatgt cttctggtag tacttcatat
    41461 tcatgcggat ctgttccgac tggtacgata ctgtggatat ctatttgatc tgttccgacc
    41521 tcttttgcca tgtccgccaa gatcgaattg gtagccacga ctgacaactt ttctttactt
    41581 ccttcatccg cttggtcaga agcctgcttt ccgcaaccgg ctaataccaa gaaactaact
    41641 gccaagatta aaaagagtga tttttttgtt ttcatctatc tgcttccttt ctgaaataaa
    41701 attccttttg ttggagaaaa taaaaaagca aggataaaaa atgcggtaca tgctaacacg
    41761 atcgtagctc ctgatggcca attgtaacta taactgaaaa acacaccgac aactgcactt
    41821 agcataccga ttcctgcagc tgtaatgatc attttcagta aatggttcgt tagcaagtaa
    41881 gccgtggcgg ctggtgtgat caacatggca atcaccaaga ttgttcctac tgtctgtaaa
    41941 ctgactacag ccactaatgt caaaaagaac atcaaaagat aatggatcag cgatgtgttc
    42001 agcccataag cttttgccat tgtcggatcg aatgatgtga tcttcaattc tttataaaag
    42061 aaaaagacaa atatcaagac gattccacta acgagtgctg tcagcaacaa atcgctttcc
    42121 ctaacagcta agacattccc aaataaaata tgatacaaat ctgtcgcact ctgggcatat
    42181 gaaatcaaga taatccctaa tgcaaaaaag gagctaaaga caattccaat cgctgtatca
    42241 tttttcaatc ggctccgctg agtcacgaaa ccaatcactg ctgctgttag catcccaaaa
    42301 gcagtggctc caaagatgta actaaaacca aacatataag aaatggctac acctggaaga
    42361 actgcgtgag agatagcgtc tcccatcaaa gacatccctc gtaaaataat aaaagaaccg
    42421 atgactccag aagcaagtcc tacaagcatg gaagtgacca aagcgtattg caggaattga
    42481 taattcatta atccatcaat aaaggattgg atcatttttt ctctcctcct tttactaaat
    42541 gtctgatgat ctcaccatag gccaattgaa ggttcttcga tgtaaagact tcttgtactg
    42601 gaccggaagc gatcagctgt ttatttaaaa gaataacctc atcgaaatat tcttctactt
    42661 tatgaagatc atgatggacg atcaaaatcg tttttcctga attcttcaat tcctgcaaga
    42721 tgtcaaagat ctttcgttca cttaacgcat caatccctac gaatggttca tctaaaaaga
    42781 tccattctgc tccttgggct agagctcttg caataaaaac tctctgaagc tgtccacccg
    42841 atagttcgct gatctgtctt ttggcatatt cttccatccc tacttttttc aaagcttgtc
    42901 ttgcacgttc tttttctttt ttcccaggtc tttgtccaat tcgtaaagat ggatatgttc
    42961 ctaaaagtac aacgcctaat acatcaattg gaaaggaaag atccaattca cttcgctgtt
    43021 ccacgtaggc tattttttta cggactgagt ttaccgactg tccagaaaag gtgactttac
    43081 cagtagtagc tggtatcaac tctagcaaag atttcataaa tgttgatttt cctgcaccgt
    43141 ttggtccgat aataccggta attttttgtg gatttatcgt caagttgata gttttcaaaa
    43201 cagttttccc ttgataagcg gctgaaaggt cttgaattac aatggccgta cgttccaaat
    43261 cttacactcc tttttaggtt tacctaactt tttatttaaa tatagtttaa ctaaaatgga
    43321 aagcattttc aagtagaatg atgaaaaagt ttttttcgaa ttttcctcgc attttatgaa
    43381 aattttctgt agaatcacat caagagttca ataaggctaa cctaataatg aaaaacatgt
    43441 gttgaaacgt ttgattattt tttcttgttg actcaacaac gaaaggagtt tttgtatgga
    43501 agaagaaaag ttaactcgaa gtcttagtgc ccgtcatatc caaatgatcg cactaggtgg
    43561 aacgatcggt gtcggtctgt ttatgggtgc ctcctcaacc atacgttgga cagggccctc
    43621 agtgatggga gcctatgcga ttgcaggatt ctttttgtat ttgattatgc gtgctttagg
    43681 cgaaatgctt tacgttgatc cttcgactgg ttcttttgca aattacgcga gcgagtacat
    43741 ccatcctgtg gctggctact tgacccgctt ggagtaatat ttttcaatat attgtcgtag
    43801 gaataagtga agtgattgct gtaggatctt atatgaatta ttggtggcct gatttgccgg
    43861 caattattcc cggaatcatt gtcgtcttgt ttcttatgct ggcaaatctt atttctgtca
    43921 aggcgtttgg cgaattagaa ttttggtttt cgatcatcaa agtcataacg atcattttga
    43981 tgatcattgc aggtcttggg gtaatcttat ttggatttgg taatcatggt caggcagtag
    44041 ggatttcaaa tctttggaaa aatggtggat tcttcactgg aggcgtcaaa ggatttttct
    44101 ttgcattatc gatcgttgtt gcttcctatc aaggaatcga actgatcgga atgactgctg
    44161 gtgaagcaga gaatcctaaa aagacgatca ttgaagctgt ccagtccact atcggtcgaa
    44221 tcttgatttt ttatattggt gctattttta tcattgtgag tatctatccg tggaatcaat
    44281 tgagtgagat tggttcacct tttgtacaaa ctttttctaa agtcggcatt acatttgctg
    44341 caggactgat taattttgtc gtgattacag cggcattatc aggttgcaat tcagggattt
    44401 tcagcgcaag tcgtatggtc tatacacttg ccataaatgg aaagatgtct aaaaaatttc
    44461 tgaaactatc tcgtcacggt gcgccttttt atcctgtcgt agcaatctca ggtggaatct
    44521 taattggtct gatcttaaat tatcttctac caatgttcat caaccagtca gaaaatattt
    44581 tcgttttcgt atacagctca agtattttgc ctggtatggt tccttgggta gtgattttga
    44641 tcagcgagat tcgcttcaaa aagaagcacg cagataaaat gcatgatcat ccttttaaaa
    44701 tgccactatc tccttatacg aattatgtga cacttgcttt tttagctatc gtattgattt
    44761 tcatgtttat caatcctgaa acgagaatct cattgattat tggactcgtt ttcttgcttt
    44821 acatgacgat ccattacttt gtacgcgaaa aaagaaccgg aaaataaaaa aagaacgaag
    44881 cttcacctta gtggaagctt cgttcttttt tattgctttt atcaattcaa ttttagcgtc
    44941 tcaccgggag tcaggaaata attctccatg ctcatcccat tcagcgacaa gatcgtttct
    45001 actggtacgc cagttcgttc ggctatttga tttggacctt ctccttccaa aactacggtt
    45061 gtcgcagcct gtgaagtcgc gctgttggta ttagtttcag aggaatctgt tgtgtcttgt
    45121 gttgttcgag cttgcatttc agaagcttct accgactctg ctgtctcaga atcagaagat
    45181 gttgtgtctt gtgtgcttgt tgactctgct tgaagagagg cgctagtctg caaataaata
    45241 tcggaaatct tagcgacatg attcgtataa ttagccgata attgattgat caaagtatct
    45301 aagtctacac cgtctttatt ttctgctgcc tgatacgctg cacgtaattt tctgatccct
    45361 tcgtcggaga ttgcttgaag ctcacgtgct ttttggttag caactgctga taaaccagct
    45421 attccctctt gatttccctg aatttctgtc tggtattctt caatcaatgc aggcgtcttt
    45481 tcttcgatct ttttcgaata atcatttacg attgcttgaa gttgctctgg caaaccattt
    45541 gctgtttttt cttcagaagt ttgtgtctct tttgttttag ttgatgactc acttgtttgt
    45601 ttcgtctctg ttttctttgt cgttgtttcc gttatggtcg tacttttcgc ttctgacgaa
    45661 ttttttccat gaaaatatag acccgcaact cctcctgcta tgatcaaaaa cacggcaact
    45721 gctgccccaa tcatgatcat ccgcttacga gctgcctgtt tttgctgtct tcttcgggtc
    45781 atccgaacat tttctcccca ctcattttca tcatacattt ttttcaccac caatttttat
    45841 gtataatagc gttatcaaac gcttcatatt cttattgtag caaataattg tcgctgtgca
    45901 catttttatc tttgttattt ataagaaaat ttcaccagtt gagatgattc caagattgtc
    45961 cgtcgatttc tccttgcagc tgcattgttc gttcgtctat ctcagccatc agtttcttta
    46021 tttcatataa gagcgcacgg tcttgatatt ctgatttttc gcttaattca tctaattgtt
    46081 ggatcagcca atcatttgtc ataatgaagt tcctttcatt tcttgcagtg taaaggtcaa
    46141 gtcttcgatc tgctcttttg cctcagtcag tgcttctacg atatatgctt gtttttcaga
    46201 ttcttcttcc tgcattttct gattttcctg tactctttga ataaaccagt caatccgctg
    46261 agtcagcgat ggtttgcctt ccaatgagag atactgctga taagcaatta gcttctccca
    46321 acgtttttcc tgggataaat acataaattg tgctaaaacg aatggcggaa gataggtcat
    46381 atggaattta tttgcgattc gctgatacgg cctcaaaaat tcggaaatcg tatattcttc
    46441 ttttcctcca gcttggtatt ctttttccgc cacacctgtt gtcaatacga ttcctagttc
    46501 tttccctttt aatacatgtg ctgctcgttc caagacatta tcttgccaaa tttttaaatg
    46561 agcaggagaa ctataccagt aaaacggaaa ctggaaaatg atccgatcat gctgggccaa
    46621 gagctgtagt tcagtctcta tatctatttt tccgtctgga taacttgatt ccaaatgatg
    46681 ccaagtagct ggtaaaccag cagaagcttc tttgaaaaat tgctgattta aagattcttc
    46741 gatcgttgga tggctaatga tgataagtgt acgcatccct tttcctcctt tttagtcttc
    46801 gctttacagt gtagcataac cgccacaagt ttcttttgcc gatgcttgtc attttaacca
    46861 gactaatcag gttgtccaag aaactgcggt ttgtttttcc aactgttttt tcaaggtatc
    46921 caaagcaata ttcttaaaat tttcgttttt catacgttta cgatagttcg tagccgtttc
    46981 tccggtactc tttttgaaca ttcggctaaa tacgactaga ctattgaacc ctacttgata
    47041 ggcaatactt tccacggatt catccgtcag agaaagaaga aacgcccctc gattgatccg
    47101 taccccgatc aaatattcct tgatactggt acccatatga tttttgaata ctcgcgacaa
    47161 atggctccga ttgaccgcta aatgctgggc gatttcctca acagacaatt tttcagcata
    47221 atgtgcctcg atgtatttga ctgtttcaac agctaaagag gaatgaacct tttgtacacc
    47281 accgctgacc tttccgccat cttttaaaag gactgataaa aaacggtagg ttaatgctgt
    47341 taactgtaat tcattttcca aggtttcttc cgtatctttc atgcattcta aaataatgtc
    47401 gatatatttt tgtatgtcag aagagaccat cgtgtattgg tcttctctga aaagcgactg
    47461 ccgaatgatt tcttctgcag cactcccacc aaatgaaagc cagcaataca tccacggatc
    47521 ttctccatct gataagtaaa acgtcgagtc tcctggacga atcaagaaca gatcaccttt
    47581 tttcaattgg aattgttgat ttttcacatg ataagatcct ttgccttcca tcacgacatg
    47641 caggatgtaa tcattgcgaa tagcaggacc aaaagaatga aacggcatcg ttttagagaa
    47701 accacaaaaa tcaaaataca attctttttc tacttgttga tgttcctttt ttaaaaaaat
    47761 cgattgctcc acgtctatcc ctccttactc ctttagtata atgcaacaaa aagttaaata
    47821 aaagtcacag aaatatatta aaaaggaagc gatttcttgt taagtttaag tcattaaaag
    47881 atctttgtta ttcgttgtaa ccggtttact tagtattata tattgaacag gagaggaata
    47941 cagattatga aaagcaaaat gatccaacgt gtgtcctacg ctttaggcgc ttttggacac
    48001 gacacattct atgttacatt aagcacttat tttatggtat tcgtgacaag ccagatgttc
    48061 gcaggaacag ataaggcaac gaatgcaaaa atgattgcta cagttacaag cttagttgta
    48121 ggtatccgct tagttgaaat tatttttgat cctttgattg gtggcatcat cgataatact
    48181 cgtacaaaat acggtaaatt caaaccatgg ttagttatcg gcggcgttgt tagttccgta
    48241 ctcttggtag caatctttac caatttcttt ggcttagcta ctcataatac gactttattt
    48301 atcatattat ttgcaatcgt tttcatctta ttggatagtt tttattcatt taaggatatc
    48361 gctttttggt caatgattcc agctttgagt acggaaacaa aggaacgtga aaaatttgct
    48421 acgtttgctc gtttcggctc ttctctaggt gcaaatggta ctactctagt cgttgtccct
    48481 atcgttactt tctttaccta tcttgttact cataaacata ttgaaggcgc ttcaggctgg
    48541 ttctggttcg gtgtgattgc tgctgttatt tcaggcggta ctgcgattat cactgccttg
    48601 ggcacaaaag aagtcgatac tgcgatccgt cagcaaaatg aaaaagctgg gatcaaagat
    48661 gtgttcaaag cagttgctca aaatgatcag ttgatgtggc ttgcccttgc ttatatcgct
    48721 tatgcgattg ccaatgtagc aacaactgcc gtattattct acttcttcaa atatgtactt
    48781 ggccaaccaa ctgaattttg gatcgttggt ctagttgctg ccttacttgg tttagtagct
    48841 gttccactat tcccaatgct tacacgcgtc atctctcgtc gctacgttta ccttggaggg
    48901 atcgcaatga tgatttcttc ttactttttc tttacgatcg caggttcaag tttgccaatc
    48961 gttatcatcg ggctagtatt gttctacttc cctcaacaat tgattttctt atccgctttg
    49021 atgacgatca cagactctgt tgaatatggt caatggaaaa atggtatccg taacgaagct
    49081 gttactctat caattcgccc tttactagat aaaatcgctg gtgctttgtc taacgggatc
    49141 gtagggtttg tcgctatcgc ttctgggatg actggtaatg ctactgctgc tgatatcact
    49201 gctcatggcg taacgacttt caaagcttat gcattctatg ctcctgctgc tttgatgatt
    49261 ttctccgcta ttatttttgc ttggaagatt acattgacag agaaaaaaca tgcacaaatc
    49321 gttgagaaat tggaaaacaa attggctcca gctgatacaa tggaagatga acttcacgat
    49381 gcagtagttc cttcccatta agaaaggatc ttgaaaatga agattacaga aaaagatttt
    49441 ggccaaggtt atcacttgat aaccttggag aacaaaaaca agctagcact ttctatctct
    49501 gatttaggtg ctagaatcgt cagtttaaaa tcaaatgatc gagaattagt tttgggattt
    49561 gacaccgctg aagaatatat cgaaaaagat ccgtatatcg gtgcttctat cggtcgcacc
    49621 gcagggagaa tcgaaaatgg ccgcttttct ctcaatggaa aaacttacca attagccaca
    49681 gatccaaaaa ctggacataa tctgcatggt ggtgctcctg gatttgaatt aaaaaaatgg
    49741 tcttatgtca ttttgaatgg cgaaaatgaa gcttctgtca tttttactac tacaagtccc
    49801 gacggagaac atggttttcc aggtacaatg gatgtggaaa tccgctatac tttgacaaaa
    49861 gataatatct ggcgagtgac ctctcgcggc accagtgacc aagatacttt attcaatccg
    49921 acaaatcatg tttacttcaa cttgacggga gatgcttctc agtcaatcga tcaacatgag
    49981 ctttggctca atagcgaagc ttatgctcct ttgcgaacag atagtattcc tataggggta
    50041 aaagaaaatg ctgcaggaag tgctttcgat tttcaaatac ctaaaaaatt agcgtccgtt
    50101 tttgctagtg atttggatca aaaaaatctt gttgacggaa tcgatcatcc atttttctta
    50161 aaagaaaccg gcttgggtaa agaagccgct cgcttgacta gccccgataa aagaatccaa
    50221 gtagatattg ctacagatgc ttctagtgtg gttattttca ctgcaaattt cggcacagaa
    50281 acaccagaaa tgcgcaaccg aaaactggca catcacggtg gcatcacatt tgagactcaa
    50341 acagctccag gtgcagagcg cttctcagca tttggttcga ttcatttaaa agccggatca
    50401 gtatttgaaa cagtaacaga attcaaaatc aaaacaagaa aggaataact catcatggaa
    50461 atcaaaagaa gcttaaacac aaaatttgcc gaaacattcg gacctaaaaa aactacacaa
    50521 tacttctcac caggacgcat caatttgatt ggtgaacaca cagattacaa tggaggccat
    50581 gtcttccccg cttccatcac ttatggaacg caaggtgtag cagcacctcg agacgataat
    50641 aaaatattag tttattccac aaactttgac gatatcggtg tcattagttt tactttagat
    50701 gagctagaat atgataaaaa agcaaactgg gcaaattacg taaaaggaat ggtccttaaa
    50761 ttaaaagaag ctggacactc aatcgatcat gggtttgagt tattagtgga aggaacaatc
    50821 cctaatggtg caggactttc cagtagcgct tcattagaat tattagtagg tgttgtatta
    50881 gaagatctgt ttgatttaaa aacagatcgc ttggaactag tccaaacagg taaaaaagta
    50941 gaaaatgaat tcatcggtgt caattcaggt atcatggatc agtttgccat cggcttcggt
    51001 gagctagatc atgcaatctt attagataca aatacgctga aatacgaaat ggttccagtg
    51061 aaactagatg gttatgcaat cgtcatcatg aatacgaata agcggcggga attggcagat
    51121 tcaaaataca atgaacgccg tagcgaatgc gaagaagcct tggcacgttt gcaaaaaact
    51181 ttgcctatct cttctttagg agacttagat gaagaagaat ttgaatcaac tattgaccaa
    51241 atcggcgatg atacattgat acgcagagct cgccatgccg tttctgaaaa tcagcggact
    51301 ttgaaggcaa aagctgaatt agaagctggg aacttagaag catttggtca actgttaaat
    51361 gattctcacc actctcttcg ctatgattat gaagtaactg ggatcgaatt agatacacta
    51421 gtagatgctg ctcaaaaaca agaaggtgtc ttaggtgcac gaatgacagg agctggattt
    51481 ggtggctgtg cgattgctct tgtcaaagaa gaaaatatac ctgccttcaa aaacaatgtc
    51541 tatgatgaat acatgaaagt tgtcggctat gctccggaat tttatgttgc acacattgga
    51601 aatgggacaa caaagatcga tccagaagct gttcatgttt gataaaaaaa tcaacgatct
    51661 cagctaaaaa caaatagata aaaataacct ctcagcaatt tccaaatgtg agccttttgc
    51721 tcgtatttga aaattgctgt tttttattga cacggaaaga gaacgtgtgt tctaattgtg
    51781 ttgaagaggt gattgttatg tgggcgaatc aaaatccggt atttgtttat gaaaaagaac
    51841 cttcaagaga tattttatgt attgactgca aatcttttta cgcctccgta gagtgcgttg
    51901 aaaaggatct tgatcccctt acaactaaat tagtagtcat gtcctatccg tccgattcga
    51961 cagaaacacg gggtagcgga ttaatcttgg cttccagtcc tgcagcaaaa aaagcttacg
    52021 gcatcaccaa tatcagccgt gccagagatc ttcccttccc ctatccaagt gatttatata
    52081 ttgttgcccc aaggatggcc tattatatgg aaaagaacag agaaatcaat tctatctata
    52141 aaaaatatgc agacgaagcg aaccatcatg tctattccgt cgatgaaagc ttccttgatg
    52201 taacaaatag catggcactc tttggtaaaa caaatgcgta cgacatggct aaactgatcc
    52261 ataaagatgt gtttgagcag accggaatct acacgactat aggaattggc gataacccgc
    52321 tacttgctaa actagcctta gacaatggct caaaagacgg aaagcaaatg tttgctgaat
    52381 ggcgttatga agatgtacca gaaaagttat ggaaaatctc agatatcact gacttttggg
    52441 gaatcggcaa acgaacagca aaacgtctga aacaaatggg tatacattct gtttatgatt
    52501 tagctcacgc ggattattat cacttgaaaa gcaagctagg ggtcatcggt actcagcttt
    52561 atgcccatgc ttggggcatc gatcgaagtt ttttgggaca agaatataca ccaaaatcaa
    52621 aaagtatcgg aaatagtcaa atcctagata gagattatac aagacgagaa gaaatcgaga
    52681 tcgttatcaa agaaatggcc gaccaagtcg gcactcgctt gagacgatct gcagcaaaaa
    52741 cacaagtagt cagcttatgg gtaggatact ctttaggcta tcttgatcca aatggcaaga
    52801 ccgggtttca ccagcaaatg aaaatcgaag cgacaaatgc tagcagagat ctagcagatg
    52861 ctttattgac cattttccac cagcattacc actaccagga tattcggcgt gtaggcgtga
    52921 actgttccga cctcgtatac gcgacaggtt tacagcttaa cctttttgaa gatcctgaaa
    52981 agcagataaa tgaagcgaaa gttgattttg ttgtcgatac gattagaaaa aaatacggct
    53041 ttcaatcaat catccatgcg catagtctct tgcaaggagg acgcgccatc gcacgtagtt
    53101 ctctcgttgg cgggcatgca ggtggtatga gtggattaga aggtggaaaa gatgagacgg
    53161 acagcaaaaa aattcattga ctataacgag tatcgagatc ggccatttgg attaaaatgg
    53221 gggactgctt ttgcgatgga agaactagtc aacggtatca aaaaaatgaa gaagaagcac
    53281 gcaaacagcc tcttcctaaa caacaaatga cattgcaaga aatcgatagt atactgacag
    53341 aagccttttt atctcgtaaa gcagtaatca ttcagctcaa tttaaaagat gaatttggaa
    53401 gactcttgga tgaggtcgaa gggcacttca ttggtgaagc ctatgaagat tactttatga
    53461 ttgaccatca gccgatattg tgggaagacg tacggtatat tgagttaaag gaaacaaaaa
    53521 aatggtttgt gacatgagag gttgtgacag aagtgatcaa cttcaaaaaa taagaaagga
    53581 tttttcgaaa attgcttctt aaatttttgt ggaattttgg cttatttttc gaagaagcaa
    53641 cttctggaac aacgtatatt agatatcaga ggttgtgaaa aagtcgctta gttttgagta
    53701 acaagccaag gcgctgattt cacaacctct gtctatctat ccatctattc ggtaagattc
    53761 atgcatgacg tcttctttat ttagtatgta gagccctttt tcttctgacc attcaacata
    53821 aatcagctgt tttacatctg catagccttc tttcttcaag ttctccataa gccatgcttc
    53881 agtcaattga ttggactgaa gcactttatg ctgaatttgc ccttcatcta caagcaggat
    53941 cgataaagct ttgtcttcat ctgatttttt caatacactc atttgaccgg cattctctag
    54001 gataacatgt ttggcatttt caagaaaaaa gcattcttgc tgtcttaaga ttgctcgcaa
    54061 ctgctccatc tcgatatggt tatttgtcaa ctctgtcatg ttgatgacgc cgtctttgat
    54121 tagaacagat ggctcgcctt tgacccaacg attgaccttt tcattttttt ggacgatacg
    54181 ttcgatacca taaatcatta ctgcccaaag cgcaatggca aataggacat gccctacatg
    54241 gacattgtca tcataggttg attcttctaa gatcccacct aaaacaagcg tatagactaa
    54301 atcaaacggt gtgatttctg acatggattt cttcccaagc aaacgtacca ctaataataa
    54361 accgatcaac ccgaacacca gtttcattgt aattgaaaaa atcatttttt ctccccctaa
    54421 ctatctgtta attaaattat atatgctttc tcacgaacac gcatggaata tacaaggaag
    54481 aaatgtatcc ttttactaaa aaaaggactg tgacactgta gtgaccccca aaagttagac
    54541 ttttttggag tggagaaatc cactcctttt ttttatgctc taaaatgata tttttacaca
    54601 accgttacgg ttgttttacg aaattggacg agactttgcc agtttaattt ctgttttatc
    54661 cgttcattat tgtagtaata gatatagcta tcgatggctg attttaattc ctcgaaacag
    54721 ttataaactt tcccgtgaaa aatctcttgt tttaataagc caaaaaaatt ctccataagt
    54781 gaattatcta agcagttccc tttccgagac atgctttgaa agattttgta ctccttcaat
    54841 ttgtttctat aagctttcat ttgatacgcc caaccttgat ctgagtgaaa cgtacgacga
    54901 tagggacaat cgttagtggt ctggatagct tcctccaaac cttccattac cgctaatgca
    54961 ttgggctttt cagagatacg ataggataaa atctcactat tgaacatatc cataaaagga
    55021 tctagataca atttcttttg acggataatg cctttggcat ccacttcatg gtatttaaat
    55081 tcagttgtat ccgtcgtgat tttctgatgg cagatactgg tgtagaaacg acgatggatc
    55141 cgatttttgg ctactgctcc aacttttcct cgataagaat tgtagcgacg tgatttacgc
    55201 gtgtatgccg ttacttttat tcctagcttc ttgatcaagc gctgaacttt ctttttattg
    55261 atagagaaac cgcggtttct tagttcattg gtcatccgta aacagccata atccttgtgc
    55321 ttctcccgaa ttttaagcat ttccgcttca atctcttgat ctggattttt acggtccaat
    55381 cgcctttgcc atccaaataa tcatgaacga tctttaattt aagttcaaaa gtatatttaa
    55441 ccataaaaaa taccgacctc caaaagttag attttttggt ctaacttttg ggggtcggta
    55501 cacaaatcgt gtcacagtcc cttttttgaa aataaacggt gttcaaaagc ttgcatctgc
    55561 ggtaataagt ccagccaagt taaaaacata agaagctgtt tttacttggc tgttcttatt
    55621 acttgatgca aggcagcttt ttcacaacct cttttcaaat atttcgtttt cttattctac
    55681 aaatggttct tctcctaacg cttgttgagc ggctagattc aacatgctcc attgtcggtc
    55741 aaagcctggc tggaagaaga agtcagcttc tgctagttct tctaaagtca gtttgttttg
    55801 gatcgctagt gccaatacat ttccttgacc tgtaacatca taggtagata atactgctcc
    55861 tcctagcaat tgatgggtca ttggatccga gaataattgg atggacactt ttggatttcc
    55921 ttgttcttct ggtacatatt ttggtcgtaa cgtatcttca taataagaca ctcgtacatc
    55981 tactcctgct tttgctgctg taaagctatt caatccgctt gctgcaaaat gatagtcaaa
    56041 gacacttaat gcagaggaac ctacgactcc gccgaacggt ttgtttggta cttcttcaaa
    56101 aagatgtttt actacataac gtgcttctct acgtgcaaca gtcgctaaag cgatcggcat
    56161 ttttttgcgt gctgggatag aataagcaag tgtagcatct cctactgcat acacatctgg
    56221 aagattcgtt tgcaagtatt catttgtttg gatccagcca cgttcatcta agtcgacgat
    56281 cccttttaac cattctgtat ttgccttcac accggcagct tgaatgacta gatctgctgg
    56341 gatttctttt tcacttgttt tgattgcctc aacttttccg ttaccagtaa aagcttcgat
    56401 ttttgcattt gtcaaaactt caataccgtt ttcatttagg tgttgttcta aaatatctgt
    56461 catctcagca tctaaataag tgcctaaagg tctatcgatc acatcaagca atacgacttc
    56521 tttcccagct tttcggcttg cttctgctgc ttcgatccca atgtaacccg cacctacgac
    56581 agcgattttt ttaatagccg gatcatttaa tttttctttg attttggttg cccaattgta
    56641 tccacgcatc aagtagacat tttctagatc tgctcctggt actggcagat tgtttggttt
    56701 gacaccagaa ctcaaaatca atttgtcata aggatattct tttgtttcgt tatctgatgc
    56761 gctagtaacc gttactgttt ttttatcggc atcgatcgtt tttacttcgt gattatttaa
    56821 aatatgaaca ttggattgcg gaaagttttc tggtctgaaa ttacgtacat catttacatc
    56881 tgttaccttg tcttctaaat acagctccat accacatgac atgaaggaaa tatagtctcc
    56941 tgcttcaaat agcgtgatat ctacattttc accgtatcgt gtcaatagtt ccaagatcga
    57001 ttgatgccct ccatgagatg cacctacaat gacaactttg attttttcca ttgatgaaac
    57061 ctccttgaat attcttttaa aatcattcta aacaatttaa acttaacatt acattagtta
    57121 tgaatcaaaa gaaacgcgtt catttgaact aaatttaaaa aacaatcgtc tccttgcaga
    57181 atataccgca aaattaacga ttgttttttt gataaaatct atgaatcact gttctgttaa
    57241 aaagtctttg atccgtttgc aggcctcatg taatttttcc atgctgctag cataagaaat
    57301 ccggatataa ccttctcctt ctgggccaaa tgcaattcct gggatacacg caacttttgc
    57361 ctgttccgct aattctacac aaaactgcca agagtcagtt tgaatggcag ctgggagttt
    57421 gcaaaacaag taaaatgcac cgtttggctg ggtcacttca aatcctaaag gcgccaattg
    57481 ctggaccaga tagtctcttc gtgtttgata ttgctctttc atattctcgc tatctttcac
    57541 cccatttatt agcgcttcag ccgcagcttt ttgcgacatc gttgtagcgg cagtcaccag
    57601 atattgatgg actttaatta gttcgtcaat aagggctttt tgagcaaaaa taaagcccac
    57661 tcgccaacca gtcatcgcat gtgacttgga taacccgctt atcacgattg tttgttctgg
    57721 aagataagta gctatggaca tatgcgttcc actataagtc aattcagcat atacttcatc
    57781 acttataaca aataccggat atttttttaa aacctcagcg attgctttca attgttttgc
    57841 agacaatgtc gtcccagtag gattgttagg atagtttaaa atgactgctt tgacagctga
    57901 tccatattgt tcaaatgctc gttcaaattg ttccggctga cagacaaacc ctgtgtcaga
    57961 agtatctatc gggatcaatt cagcaccagc tagttccact aatggctgat atcctgaata
    58021 agcaggcgct ggaataagaa ccttgtctcc ttcttccaaa acagataaca acgcagaggc
    58081 aatcgcttcc gttgcaccaa ctgtcgtcaa aacttccgtt tgcggatcat aagttaatcc
    58141 ataacgctgt tgctgaaata tacaagccgc ttcccgcagt tcctctaatc ctctcattcc
    58201 ggtatagtga gaaaagtctt cttcaatcgc tgctattcct gcttgcttga catgttcagg
    58261 agttggaaaa tccggttctc ccagggtgag tttgatcaca tctggtatcg acgatatttg
    58321 ctgatcgaat tgtcgtattt ttgatacttc tattctagaa agcctaggac taaatcgatt
    58381 ggataaattc atcattattt actcgctcct cttttgaact gctatcgatt tttacaagaa
    58441 gattttctgt aaaaagaatc gttttgtacc attctacacc attttctaaa acatccatat
    58501 caaaatcgaa cgtcggatca tgtaaagcag gggtatcacc gacacctaaa aagaaaaata
    58561 cacatggata ttgttgcgta tatatgccaa aatcttcggc ttgaagaact ggagcatcta
    58621 attcatgtag tttgtttgaa tctaacagtg ctgcatataa gcctctatgg ttgattacag
    58681 ctggatagcc gtcattatag cgaaaagaaa tagtagctgt agagtgaaac tgttctgcta
    58741 aatggtctaa tcccctcttc aaataatttt gcatatctga actgtaagaa cggatacttc
    58801 cggatacaat aacttctcca gctaaaacat ttcggatcgt tccaccttgg atttggccaa
    58861 atttcattag atgattccac tctgccggta attgccggtc aaaatcataa acattcttca
    58921 aaaatcgtac agctgcctcc agactatcga ttcctttttc actagaagca atatgtgcag
    58981 actggccttt aatgataatg tctgtttcac tgctttgtgc catcaaaggt cctggtcgag
    59041 agaaaacttc tcccttagct agtccaggcc atagatgaaa gccaaatatt gcttgtactt
    59101 catatttatc caacaatcct gactgaataa cgctttgtgc gccaccggaa atttcttctg
    59161 atggctgata gatcagtact acattataaa taagatcctc aatgtgttta gttataaagt
    59221 cagtcaaccc taaaagcatc gccatatgtc cgtcatgacc acatgcatgc atataacctt
    59281 catgcttaga agcaaaagag agattcgttt cttctttgac tggcagtgca tcgatatctg
    59341 ttcgaaaagc aatcgtttct tcttgctgat tatcaaaata aaggagtagt cctgtttcgc
    59401 cgatttcatg gataacggcc tcgctgtttt ttacttgttc atataaatat ttttttgtct
    59461 tgaattcatg aaacccgatt tcaggaattt gatggagtgc cattcgatat tctttcagca
    59521 tccgtattca ccatcccttc atagataccc ttcactactg tttcatattg attattcggt
    59581 acaccgatga tcagattcaa ctcctgtgct ccttgtgata agatcgatgt gcgaatttct
    59641 aatttgttca atatcgataa cactttccca gataatccaa tcaattcttt atgcggaccc
    59701 ccaacgacag agatcaaagc taagtcttcg atcacgacga tttcttccac gccaagtgtt
    59761 tcttttaatt ctttcgtgat gagaaataac ttatcggcaa tcgcttctgc tgagacgatc
    59821 actccgatat tgtcgatccc tgaaggaata tgttcgattg atatctcatg tttagcaaaa
    59881 atgctcattg ctttccagat aaacccgatt tcatcggaca tatgacgttt gaataaagtg
    59941 atggaaagaa aatccttgcg tccagctatt cctgtcagtc cattttcctt ttctatttcg
    60001 tgattcgata tttttgtccc ttgagcgaaa ggatcattgg tattttttat ttggatgggg
    60061 atatcagcct cttgaactgg gaaaacagct gcttcatgaa gaacgttagc ccccatataa
    60121 gccatctctc tcagttctct aaaagagatt tcctcgatga ttttaggatg atcgatgatt
    60181 cgcggatcag ccatcatgat tcctgaaaca tccgtccaat tctcataact ttccgcttgc
    60241 aacatcttcg ccagtatcgc gccggtaatg tcgcttcccc cacggcccaa taatttttct
    60301 tttcctgcag ggttcgcccc gtaaaaccct ggaacaacca ttttcggata tcttttaaat
    60361 gcttttgtga tttcctgtgc tgttttttcc tgatcgattt tcccatcata gtcaaagaaa
    60421 atcaggtctt ttgcgtcaat aaactggtaa ccaagatact cagccatcag ttgagcagtc
    60481 agatattcac ctctacttac taaataatct tcagttatct tttcgtcttc cagttgtttc
    60541 tgtatgcgtg ctagttcatc ttcaataggt aactgcaggg caagaacatc tcttacttga
    60601 atgaaacgat cacaaatcct tttccaaagg ggtgtccaat caacatgatg ctgaaggtaa
    60661 gcataaatca aataaagtaa gtctgttact ttgtcatcat ctgacgtacg tttgcctaaa
    60721 gcagaaacaa cgatcacttg gcgattggga tctgaaagaa caattgtacg gacttttttg
    60781 aattgctctt catgagacat cgatgttccg ccgaatttcg ctactttcag cgtattactc
    60841 atcttgccac ctccgctatt ttctgcatta aagctgcagc aatctgtacg gcattcgcag
    60901 cggctccttt gcgtatgtta tcggcagtcg tatagaacaa caatccgttc tctaaagaag
    60961 tgtcttttct gatcctccca acataaacca tatctgttcc tctagcaaga atgctcgtcg
    61021 gatatttatg tgctgctaga tcatcttcta attgaatccc tggaaactgg ctgagacact
    61081 ctctaatttc ttccgtcgta aactcttttt gcagttgaac tgccacagag actccatgtc
    61141 cattttcgat tggcacacgt acgcaggttg ctgatactgg caaagcaggc tgatgcagaa
    61201 tcttacgggt ctcatttatc attttctgtt cttcttttgt atacccattt tccaaaggct
    61261 gatcgatttc cggaatcacc gtttggctaa tattataagg atacaaaact ggttcctcgt
    61321 cattttgcgt acgatgaaga tcttcaatgc ctttttgccc ggaaccagaa actgcttgat
    61381 aggtcgaata attgactcgc tggataccaa aggcttcttg taaagcttta agcggaagta
    61441 ccgcttgaat ggttgaacaa tttggatttg caatcagccg attcaatgta tagtcttcca
    61501 gattgacctc tggaacgatt aatggaatat ccgaatcttc ccgccatgct gaggaattat
    61561 ctatgacaaa tagtccctga cttcgtgcga ttggcgcaaa ctctttggat acagaagcac
    61621 ctgcagaaaa tagcgctaaa tcatatcctt caaatgaagt ttctgtcaat tcctgtacag
    61681 tgtgtttctt tttcttgaat acacaaactt taccggctga acgttttgaa gctaataatt
    61741 tcaatcgtcc tactggaaaa tcatattctt ctaacacttt gagcatcgtt tggccgacta
    61801 atccggttgc ccccacaata caggtatcta tttcgcgcat ttttctccat ctcctctata
    61861 attcgcgtaa cgcagcaatc aatgctgtat tttcttttgt ctgatcatca cttattttta
    61921 atacacgtgc aggtattcca ccgacaacag tttctgctgc cacatcttct aaaaccactg
    61981 ctcctgctgc cacgactgca tcttttccga tatggacacc ttcaacaatc actgcattcg
    62041 cacctaccag tacgccgtct tctacgataa ccggtttggc cgatgctggt tcgatcacac
    62101 ctgctaagac agctcctgca ccaatatggc agtttttgcc cactgtcgct cgtccaccta
    62161 agacagcacc catatcaatc atcgtgtttt caccgattac tgcaccaata ttgataatcg
    62221 ctcccatcat gatcacggca ttgttgccga ttgacacttg atctctgata atagcacctg
    62281 gttcgatacg agcattaatt tttttaatat ctagcaaagg aactgcgctg tatcttgcag
    62341 cagtttcgat ttcgatttca atgatttttt ctgattcagc ttctaaaacc ggagcaatcg
    62401 tctcatagtc accaaaaaca acgaagctgc ttccttcacc aaaaacttta ctttctttaa
    62461 attcgattgg ctcggttaca ttcagataga ctttcacagg cgtcttttta gatgccgttt
    62521 gaatgtagcg gatgatttct tgagcttcca cgttttttac acccctttgt ccattaataa
    62581 atcttctaat ttgtaataac ctggtgactg atctttcaac cagtccgctg cttctactgc
    62641 gcctgcagca aagattcgat tagaaaaaga ttcatgtttg atcgtaaata tttcatcagt
    62701 agcagcaaac aatacatcat gttcaccagg taaagaacct gcacgaatac tgtgtacacc
    62761 aatttggttt tcttctcttt ttttcccttg ccagttgtat acgggctgca gcttttgcac
    62821 ttcttggatt gtttgaagca gcatatttgc agtaccagat ggtgcatctt ttttacgact
    62881 atgatgtttt tcaatcagtt cgatctgcca gccttgcaac attgcagctg cttgcttgat
    62941 tagttgattc atcaccatga tgccgaacga aaaattagca ctatacatca caggtacatg
    63001 tttggcatgt tcttttattt cttggaactg tgattgtgta taacctgtcg tgccaatgac
    63061 taacggaagt tgatatgata agctatacga aaggattttc tctaaattat ctggatgaga
    63121 aaaatcaata agcagttctg gcagttccgt aaaagcaagc gtagttgctt ctttaggtgc
    63181 cgtccgtaaa agaaggaccg tatctcctct ttcttgtgca acttcttcga ctctatttcc
    63241 catctgtcca ctgccaatca gtccgatttt catttttcaa ccgtcctttc ttttaacaaa
    63301 agctgagcta attgtttctt tttctctttt gaaagagaaa ctaaaggcag gcgtagaggt
    63361 ccggaaggta agtctaataa tgacatggct gctttgacag gaataggatt ggtctcactg
    63421 aacaaggcat ggatcagttc aagtgcattt aattgctttt cttttgcttg ctgccatctt
    63481 ccgtcctgcg tatcttttac taattcatgg actattttag gttggatatt cgcccataca
    63541 cttattacac cgcttcctcc tacactcatt actggtagga tcaaatcatc atttccactg
    63601 taaaggaaga attcttctcc aatcaaccga gcggcatcca tcacataagc catatctcct
    63661 gaggcttctt tcaaaccaat gatattagga tgttctgcta aatttactaa tacatggatt
    63721 ggaatcgaca tgcctgttct agaaggaaca ttatacaaaa taagcggaat cggtgaggct
    63781 tctgcaattg ctgtaaaatg agcagctagt cctgcatcac ttgttttgtt gtagtaaggg
    63841 gtgatgacca aaagtgcgtc tgcccccaaa gaagcaaaat gcttcgcttt ttcaatcgtt
    63901 tctttcgtat tattcgttcc agctcctgca atcaccggca cacggccagc cactttcttt
    63961 actgtcagtt gaaggatctg ctcctcctca gattgtgtga gcgtagaaga ttctcctgtt
    64021 gtacctaaaa ctaataatcc atctgtttgt tcatctaaat ggaattggat caatttttcc
    64081 aaaccagcat aatctactga tccctcttca ttcatcggcg tgatcagcgc cacgatcgaa
    64141 ccttttatca tcttcattcc tccaatattc ttgtccattc atgaactgct gggccagcca
    64201 tttgtatcgc atcctcacca gagatcatca agtctccttg ttccaagtga acaactacct
    64261 gatctgctga aattttccca gtttccttag caaccacata agaggcacag caacctgtac
    64321 cgcaagcaag tgtccaacct actcctcttt cataggtacg gacgatcaat tcttgttcat
    64381 tgactacttc tacaaagttg acattggttt tttctttgaa caaaggatga tgacagatca
    64441 gttcacctct ttttctccag acttcctcac gcgcattttc aacaaaaaca acggtatgaa
    64501 tcgttcctaa aaataaacta gtgatcgtta ctttttcacc attgatctct atttcctggt
    64561 tttttattgg ataagtttga ttagctttga ttttttccgg agaatcatct ggcactccca
    64621 tatctacgct gcaataaaaa ggtgagggat ccaacaccgt aatttttctt gtgcctgcta
    64681 atgtctctac gttgaattcc tgttcattca tcatgttctg atcatttacg tatcgagcaa
    64741 aacagcgaat gccatttccg cacatcggcg cgcggctgcc atctttgttg taatagatca
    64801 tttccaacgg atcgattttt acggcgatca atccgtctat atcatatttt tcttttgtgc
    64861 ataaagaagc ggctaattga ctataatctg tgtcttctgc gtaatctaat aagataaaat
    64921 catttccgca gccattatat ttatgaagga tcataggaaa cttcccccct tagtagatca
    64981 gaaaatgctt gtctgcgaac aatcagtctt gattggccat tattgacaaa aacaactgct
    65041 ggtcgtgtcg ctcgattgta gttgctgctc atcgagtatc cataagctcc cgtggaataa
    65101 acagctaaaa gatcacccga ttctgctttc ggcaaataag cttctttaat taccacatcg
    65161 cctgattcac acatttttcc tgcaatcgtc actttctctg ttttttcttc cgacagtttt
    65221 gctgctaaat cacaatcgta ttctgcctga tacagagctg gacggatatt atctgtcatc
    65281 ccgccatcta caaagtaata ttttttatgt ggtgtctttt tgatgaaacc aatcgtgtat
    65341 agtgttgtac cagcttctcc aacaatactt ctacccggtt cgatcagtaa ttgacgaatg
    65401 gtcagttttc gtttttccaa agcttcttcc gtatattcaa tcagtttttt tagtgcctct
    65461 tcgactggga tcggctgatc attttgtgta taacgaatcc caaaccctcc gccaagattc
    65521 aaggaaagag gttggtcaaa atcggttaag taattcgtca atttgtcgat ttcagctaac
    65581 caagcagtaa catcaaaaat ttgtgacccg atatgagcat gaaatccttc taactctaga
    65641 tagctgcttt cttttatcaa ctgaagggct tgttggcact ctttactttc atagctcatg
    65701 ccgaattttg aatcaatatg cgcagtgacg atatattcat gagtatgtgc ttctactccg
    65761 acattcaacc gaagcatgat acagattttt tttaaatagc gttggcttaa ttctgctaat
    65821 aattcaactt ccatcaaatt atcggcaaca atatgcaaca aatcattttc aagtgcatag
    65881 atcagttcct ctggcgtctt gttgttacca tggaagtaga tagtatctct aggaaaatca
    65941 gcttgcaaag cggtatagat ttccccacca ctgacaacat ctagcccgaa tccatattca
    66001 cgaactaaat gcagcatctc aatcgtttgg aatgctttag aggcgtaaag cacttttgta
    66061 tcaaaacgtt tcgatacaaa gcctcgcttg aatgacagca tcgtttgtct catcttttct
    66121 tcatcataca catacagagg tgtcttatac ttttctgcca atgtgcttgc tgtgactccg
    66181 ccaattatca attctgtcat tttttcattc ctcttttcac tttttttccg tttttattgg
    66241 aatttcattt gataaagatt tgaattttat tggaataata ttaaacaaaa ttttctgaat
    66301 tgtctagtat atttcgaaat atttttttaa aaataagaat aaaaatggtt ataaaaacaa
    66361 aatacccgaa ctattagaag ctatttatac ataaaaacat aaattcaaca ctatttagtg
    66421 atgaaaaaat attttcgctt caatatagtt cggaatagtt cggatatttt caattttatg
    66481 aatcatttca atttcttcat aaataagtgc agttttttct ttctctagct tttgccattc
    66541 atctttcaaa atataaataa aatcaaatac ttttttattt ttcaatttgc tgattccaca
    66601 aaaaacctct tgaaaggcag atccgatgat ctgcctttca agaggtcaag ctctgttttc
    66661 aaattcttat caatccgtta gcgaattatt ttgacgcacg ttttacataa gaaccttctg
    66721 ctgtattgat ttccaacaat tcatctgttt cgatgaagtc aggaacattg actactaagc
    66781 cagtttccat tgtcgctggc ttacctgaac cagtgactgt tgcacctttg atggaaggtt
    66841 gtgtttccac aacacgtaat acgacagttg ttggtaattg aacgccgatg acttcgctac
    66901 cgaaaaattg gatttttact tccatgtttt ctaggatata tttcatttct tcttctactg
    66961 tttctacagg aatttcatat tgctcatatg tttccaaatc catgaagaaa gctgtatcat
    67021 ccatcgtgta caaatattgt acaggttttg tgtcgatatg tgctttttca aatttttctt
    67081 ctggtctgaa cgttgtgtcg tatgttgcac ctgaacggac atctttcagt ttcatacgca
    67141 taactgtatt tcctttacca ggtttatggt ggcttgcatc cagaacttta atcagtttgc
    67201 cgtcttgtac gaaagtcata ccggctctta aatcacttgc tgagatcatt atttttgctc
    67261 cttcttttct ttatcataat caactttatt gtatcagaca accggccaga aaactagagt
    67321 attctctatc ttttaaggtc tcatgcctat ttgtcagaaa aataaacacg ggtaaacgat
    67381 gctatcgaaa tatttttttc tttcaagcct ttgactttta ttttttttca tgctatcgtt
    67441 aataaaaatt ttacttggag ggatacacat gacagtcagc aaccaaaaac aattgaatcg
    67501 ttgctgttgt atggtgcata aaagcagcat actatttgtc atgtctatta attgcccttc
    67561 atagaatgag taccaggtaa cttatctttt tatctactca atttttctct atgtctttca
    67621 aggagctgat ttaatagtca gctccttttt ttattatctt tttttaggag gcccacatga
    67681 ttatctcgac aattacagaa gctattggtt ccacaccgct ttatcgcttt gacaatcagc
    67741 actattctat gcctaaaggt tctgctattt atgcaaaact agaatattta aatcctggag
    67801 gaagtatcaa agatagattg ggcagttatt tgatcaaaga aggatttgcc caaggaaaaa
    67861 tcaatgaaaa aacgacgatc atcgaaccaa ctgccggaaa tacaggaatt gggatcgctc
    67921 tggccgcact cacatacaaa ttaagaacgg tttttgttgt tccagagaag tttagcttag
    67981 aaaaacaaca attgatgaaa gcattgggag caaagatcat ccattctcct agtgagcaag
    68041 gaatcatcgg tgccatcagc aaaagtaaaa aacttgcaga ggagatatca aacagctatc
    68101 tgcctcttca atttgaaaat aaagataatc ctgctgctta ctatcatacg ttagggccag
    68161 aaatctttca tgaaatcaaa gaaaatatcc atagttttgt agcaggaatt gggagtggtg
    68221 gaacctttgc tggaacttct acctttttga aagaaaaata tcccgacatt cgaataatcg
    68281 gtgtagaacc agagggctct gtgttaaatg gtggtgatcc agcccctcac gaaattgagg
    68341 gtatcggtgt agaattcatt ccgccgtttc tttctcccct ttcaatcaat cagatcgaga
    68401 caatctctga tgtagaaggg tttaactata ctaggcagtt agcacgagaa caaggactat
    68461 tagttggaag ttcgagtggt gcggcttttg cagcagcatt aagagaaatt cgtcgtttac
    68521 cacctggtca tcgtgtcgtt acgatttttc cagacgcagc agaccgctat ttatcaaaaa
    68581 acatttactt ataggaggaa agaaacatgc acattcaaac aaaattgatc cacggaggca
    68641 tcagtgaaga tcccacaaca ggagctgtca gtgtacctat ttatcaaaca tccacttatc
    68701 ggcaagatgg cgtcggccag cctaaacaat atgaatattc aagatctggt aatcctactc
    68761 gttttgcatt ggaagaactg attgctgatt tggaaggcgg tgttcgagga ttcgcttttt
    68821 cttctggtct ttctgggatt catgccgttt tttctctttt tcaagctggc gatcatatct
    68881 tattaggaga tgatgtctat ggaggaacat tccgtctatt tgacaaagtt cttactaaaa
    68941 atggtctcga gtacacgatc atagatacga gtaatcttga taaaatagaa caatccatca
    69001 aacccaatac aaaagcactt tatcttgaaa cacctagcaa tccgcttcta aagattactg
    69061 atttagaaaa aagtgccact ctggctcatc aacatggatt gatagttatt gctgacaata
    69121 catttgctac tccttatttt caaagacctt tagatctcgg ttctgatatc gttgtccata
    69181 gcggtaccaa atatctaggc ggacacagcg atgtagtagc tggtttagtg acttctaacc
    69241 ataaagatct agccgatcag atcggatttt accaaaatgc tatcggagcc gtacttggtc
    69301 cccaagatag ctggttactt cagcgcggaa tcaagacact aagtgttcgt atggaggaac
    69361 atcaaaaaaa tgcttttgtg gtagctgatt ttctattttc tcatccagca gtagaaaagg
    69421 tctactatcc aggattaccc gatcatgaac tccatggagt tgctaagcag cagatgagcg
    69481 gctttagcgg aatgatttct tttactttaa aaaatgaaga atctgctatt ccatttgttg
    69541 aatcactcca actatttact ttagcagaaa gtttaggtgg cgtagaaagt ttagtggaaa
    69601 ttccttctgt catgactcat gcgtctattc caaaagaaaa acgagaagag gctggcataa
    69661 aggacggctt gatccgtctt tctgtaggaa ttgagtatgg tcaggatctc ataaacgatt
    69721 tagctcaggc atttgacaga atcaagaact agaagtccca ataaacgact tagcagaaaa
    69781 atctaaaaaa tatttcagat tgctacacct tggaaacgat aagtgttaga atcaagtaga
    69841 aagacgtttt tgtaaatttc actaaataat tctttagtga aaagcatcaa aacgaatgaa
    69901 caaacagata ggagtcttac aaatgagaat gaatgtcgaa agttttaatc ttgaccatac
    69961 aaaagtcaaa gcaccttatg tacgtgtagc tgatcgaaaa acgggtgcgc atggcgatgt
    70021 catcattaaa tacgacgtcc gctttaaaca accaaataaa gaacacatgg acatgccaag
    70081 tctacattca cttgagcact tgactgccga actaatccgc aatcacgcag attacatcgt
    70141 agactggtct ccaatgggat gccaaacagg cttttacttg actgtattga atcatgaaag
    70201 ctacgaagac attttagatg ttcttgaagc aacaatgaaa gatgttcttg aagctactga
    70261 agtacctgca agcaatgaaa cacaatgtgg ctgggctgcc agccatacac tagaaggtgc
    70321 acaagctttg gctcgtgaat ttttagcaaa acgcgatgaa tggtctgaag tagaagcata
    70381 gtttctaaaa gaacgtaaag atgagaagca atatagctat cttatcttcg tattttatta
    70441 aatatttatt gtctgaaaag agttctaaac gggaaaacaa atagctagtt ttcagtttag
    70501 cgctcttttt attatataaa atagaaagga gaaaacttta tgtctattta taattttgaa
    70561 actactttag aagacggcac tgtctattca ttgaaaaaat atgcaggcaa accgataatc
    70621 attgttaaca ctgcaacaaa atgcggtcta gcacctcaat ttaaacaatt agaagaactt
    70681 taccaagctt atcagacaca aggtctggtt atcttaggct ttccttccaa tcaatttaaa
    70741 caagagctag attcagcgac tgaagcagca gaagcttgta aaaccactta tggcgttacc
    70801 ttccctatgc atcaattgat tgacgtaaat ggagaaaata cagatcctct ttttacttat
    70861 cttaaaaatg aagctcctgg tactgtcact aaagcaataa aatggaattt tactaaattt
    70921 ttgattgata gaaatggcaa agtaatcgaa cgatttgcac cacaaacttc tccattgaaa
    70981 atgaccgctg caattgaatc cgttctttaa cttaataaaa ataaaaaaag atgaactatt
    71041 tctagttcat ctttttgcct ttgcgtggcg acgtcctact ctcacaaggg gcaacccctc
    71101 actacaatcg gcgctaagaa gcttaacttc tgtgttcggc atggttacag gtgtatcctt
    71161 ctcgctatcg ccaccacact gtggtgttat cttttattga gtaaattttg ttcactcaaa
    71221 actggatttg aagtca
//
LOCUS       DAKCAA010000008        66360 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000008 DAKCAA010000000
VERSION     DAKCAA010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 66360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.008"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..156
                     /locus_tag="OUE31_000600"
     CDS             <1..156
                     /locus_tag="OUE31_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221630.1"
                     /translation="KVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRPTNHTK
                     KWMAKNR"
     gene            376..1083
                     /locus_tag="OUE31_000601"
     CDS             376..1083
                     /locus_tag="OUE31_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCU0221631.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(1143..1787)
                     /locus_tag="OUE31_000602"
     CDS             complement(1143..1787)
                     /locus_tag="OUE31_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HCU0221632.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            1914..2201
                     /locus_tag="OUE31_000603"
     CDS             1914..2201
                     /locus_tag="OUE31_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221633.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            2309..2629
                     /locus_tag="OUE31_000604"
     CDS             2309..2629
                     /locus_tag="OUE31_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0221634.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            2710..4023
                     /locus_tag="OUE31_000605"
     CDS             2710..4023
                     /locus_tag="OUE31_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCU0221635.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            4020..4739
                     /locus_tag="OUE31_000606"
     CDS             4020..4739
                     /locus_tag="OUE31_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HCU0221636.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            4867..5418
                     /gene="raiA"
                     /locus_tag="OUE31_000607"
     CDS             4867..5418
                     /gene="raiA"
                     /locus_tag="OUE31_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HCU0221637.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            5640..8174
                     /gene="secA"
                     /locus_tag="OUE31_000608"
     CDS             5640..8174
                     /gene="secA"
                     /locus_tag="OUE31_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HCU0221638.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDIQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGDE
                     DAVIQSKMLTKQVEAAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIVDFAGSTLVHEDSISLTDIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKDAN"
     gene            8301..9402
                     /gene="prfB"
                     /locus_tag="OUE31_000609"
     CDS             join(8301..8372,8374..9402)
                     /gene="prfB"
                     /locus_tag="OUE31_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HCU0221639.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAVMQEEAEARI
                     NALDEKMNTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            9507..10193
                     /gene="ftsE"
                     /locus_tag="OUE31_000610"
     CDS             9507..10193
                     /gene="ftsE"
                     /locus_tag="OUE31_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HCU0221640.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            10177..11070
                     /locus_tag="OUE31_000611"
     CDS             10177..11070
                     /locus_tag="OUE31_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0221641.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            11222..12670
                     /gene="cls"
                     /locus_tag="OUE31_000612"
     CDS             11222..12670
                     /gene="cls"
                     /locus_tag="OUE31_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCU0221642.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            13007..13864
                     /locus_tag="OUE31_000613"
     CDS             13007..13864
                     /locus_tag="OUE31_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HCU0221643.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            13979..14899
                     /gene="pstC"
                     /locus_tag="OUE31_000614"
     CDS             13979..14899
                     /gene="pstC"
                     /locus_tag="OUE31_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HCU0221644.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            14899..15783
                     /gene="pstA"
                     /locus_tag="OUE31_000615"
     CDS             14899..15783
                     /gene="pstA"
                     /locus_tag="OUE31_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HCU0221645.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            15798..16604
                     /gene="pstB"
                     /locus_tag="OUE31_000616"
     CDS             15798..16604
                     /gene="pstB"
                     /locus_tag="OUE31_000616"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCU0221646.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            16620..17378
                     /locus_tag="OUE31_000617"
     CDS             16620..17378
                     /locus_tag="OUE31_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCU0221647.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            17391..18068
                     /gene="phoU"
                     /locus_tag="OUE31_000618"
     CDS             17391..18068
                     /gene="phoU"
                     /locus_tag="OUE31_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HCU0221648.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            18306..19337
                     /locus_tag="OUE31_000619"
     CDS             18306..19337
                     /locus_tag="OUE31_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCU0221649.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            19334..20101
                     /locus_tag="OUE31_000620"
     CDS             19334..20101
                     /locus_tag="OUE31_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCU0221650.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            20201..21769
                     /gene="liaX"
                     /locus_tag="OUE31_000621"
     CDS             20201..21769
                     /gene="liaX"
                     /locus_tag="OUE31_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HCU0221651.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            22066..22386
                     /locus_tag="OUE31_000622"
     CDS             22066..22386
                     /locus_tag="OUE31_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HCU0221652.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            22386..22736
                     /locus_tag="OUE31_000623"
     CDS             22386..22736
                     /locus_tag="OUE31_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCU0221653.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            22903..23841
                     /locus_tag="OUE31_000624"
     CDS             22903..23841
                     /locus_tag="OUE31_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HCU0221654.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            23856..24686
                     /locus_tag="OUE31_000625"
     CDS             23856..24686
                     /locus_tag="OUE31_000625"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCU0221655.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            24730..25755
                     /locus_tag="OUE31_000626"
     CDS             24730..25755
                     /locus_tag="OUE31_000626"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCU0221656.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            25770..26708
                     /gene="galU"
                     /locus_tag="OUE31_000627"
     CDS             25770..26708
                     /gene="galU"
                     /locus_tag="OUE31_000627"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCU0221657.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            26833..27273
                     /locus_tag="OUE31_000628"
     CDS             26833..27273
                     /locus_tag="OUE31_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HCU0221658.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            27276..27878
                     /locus_tag="OUE31_000629"
     CDS             27276..27878
                     /locus_tag="OUE31_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCU0221659.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(27937..29043)
                     /locus_tag="OUE31_000630"
     CDS             complement(27937..29043)
                     /locus_tag="OUE31_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCU0221660.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            29253..30254
                     /gene="ccpA"
                     /locus_tag="OUE31_000631"
     CDS             29253..30254
                     /gene="ccpA"
                     /locus_tag="OUE31_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HCU0221661.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(30591..32936)
                     /locus_tag="OUE31_000632"
     CDS             complement(30591..32936)
                     /locus_tag="OUE31_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCU0221662.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            33215..34117
                     /locus_tag="OUE31_000633"
     CDS             33215..34117
                     /locus_tag="OUE31_000633"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HCU0221663.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            34330..36105
                     /locus_tag="OUE31_000634"
     CDS             34330..36105
                     /locus_tag="OUE31_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HCU0221664.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(36171..37757)
                     /locus_tag="OUE31_000635"
     CDS             complement(36171..37757)
                     /locus_tag="OUE31_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HCU0221665.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            38008..38232
                     /locus_tag="OUE31_000636"
     CDS             38008..38232
                     /locus_tag="OUE31_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HCU0221666.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            38374..40125
                     /locus_tag="OUE31_000637"
     CDS             38374..40125
                     /locus_tag="OUE31_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0221667.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLMLDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            40125..41909
                     /locus_tag="OUE31_000638"
     CDS             40125..41909
                     /locus_tag="OUE31_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0221668.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIITRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTSDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMMKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPIEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVEHGNHETLLAQNGLYADMYKLQSSGI"
     gene            42235..43086
                     /locus_tag="OUE31_000639"
     CDS             42235..43086
                     /locus_tag="OUE31_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCU0221669.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEDLQVHLNDSVYIALTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDKAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRCYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVIQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            43181..45067
                     /locus_tag="OUE31_000640"
     CDS             43181..45067
                     /locus_tag="OUE31_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCU0221670.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVRVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTVARKFKVNEFVGMLLGAALMNPNLSLEVLSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVNYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAMPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKDEAGETDDIQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(45107..46009)
                     /locus_tag="OUE31_000641"
     CDS             complement(45107..46009)
                     /locus_tag="OUE31_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCU0221671.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            46240..47643
                     /locus_tag="OUE31_000642"
     CDS             46240..47643
                     /locus_tag="OUE31_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCU0221672.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLDIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETITSIYGNKETQIV
                     VSTKNDGAVPDLSADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETIGRLKEEGIEVQ
                     DELARELSSNTHIMEEV"
     gene            47643..49076
                     /locus_tag="OUE31_000643"
     CDS             47643..49076
                     /locus_tag="OUE31_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCU0221673.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWDSRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            49221..50147
                     /gene="trxB"
                     /locus_tag="OUE31_000644"
     CDS             49221..50147
                     /gene="trxB"
                     /locus_tag="OUE31_000644"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HCU0221674.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            50362..52089
                     /locus_tag="OUE31_000645"
     CDS             50362..52089
                     /locus_tag="OUE31_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCU0221675.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EENHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAKKVASYE
                     AIIKKMTEE"
     gene            52104..52454
                     /locus_tag="OUE31_000646"
     CDS             52104..52454
                     /locus_tag="OUE31_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCU0221676.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(52546..53406)
                     /locus_tag="OUE31_000647"
     CDS             complement(52546..53406)
                     /locus_tag="OUE31_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HCU0221677.1"
                     /translation="MTSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            53498..53926
                     /locus_tag="OUE31_000648"
     CDS             53498..53926
                     /locus_tag="OUE31_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCU0221678.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            54088..54264
                     /locus_tag="OUE31_000649"
     CDS             54088..54264
                     /locus_tag="OUE31_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HCU0221679.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            54291..54737
                     /locus_tag="OUE31_000650"
     CDS             54291..54737
                     /locus_tag="OUE31_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HCU0221680.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(54891..56270)
                     /gene="brnQ"
                     /locus_tag="OUE31_000651"
     CDS             complement(54891..56270)
                     /gene="brnQ"
                     /locus_tag="OUE31_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCU0221681.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
     gene            56976..57947
                     /locus_tag="OUE31_000652"
     CDS             56976..57947
                     /locus_tag="OUE31_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HCU0221682.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            57971..60163
                     /locus_tag="OUE31_000653"
     CDS             57971..60163
                     /locus_tag="OUE31_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HCU0221683.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKVNDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            60180..60656
                     /gene="ybeY"
                     /locus_tag="OUE31_000654"
     CDS             60180..60656
                     /gene="ybeY"
                     /locus_tag="OUE31_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HCU0221684.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            60640..61035
                     /locus_tag="OUE31_000655"
     CDS             60640..61035
                     /locus_tag="OUE31_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HCU0221685.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            61050..61949
                     /gene="era"
                     /locus_tag="OUE31_000656"
     CDS             61050..61949
                     /gene="era"
                     /locus_tag="OUE31_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HCU0221686.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            62092..62904
                     /gene="recO"
                     /locus_tag="OUE31_000657"
     CDS             62092..62904
                     /gene="recO"
                     /locus_tag="OUE31_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HCU0221687.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            63288..64205
                     /gene="glyQ"
                     /locus_tag="OUE31_000658"
     CDS             63288..64205
                     /gene="glyQ"
                     /locus_tag="OUE31_000658"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HCU0221688.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            64207..66282
                     /locus_tag="OUE31_000659"
     CDS             64207..66282
                     /locus_tag="OUE31_000659"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HCU0221689.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDADRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELYKAVEG
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLNQIAAMALSL
                     ASLDQIITK"
BASE COUNT        21675 a        11740 c        14165 g        18780 t
ORIGIN      
        1 aaagtagacg aagcagctga aaagttatat gatttggtca aatcagaaaa atacaatatt
       61 gaagtgaata ttccgaaaaa aggcggaaaa gcggtccagg taaaatcaaa acgcccaacg
      121 aatcatacaa aaaaatggat ggctaaaaac cgctaataat aacaaaagat ccataagtcg
      181 gcattttcat cgattttagg gtcttttgtt attttctagg ttgaacatat ctaaaaaatt
      241 gtttctgaca ataggagtag gaagaacgat gtgtgtctaa atcctctgtt gatggataga
      301 aacctttatc tttttcagtt gtgaatcagg tatataccag ttataataga agaaacgaaa
      361 ggacgggtgt acgttatgtc gaatcaatta cctgtatata tacagattca tgaccaatta
      421 aaaaatgaaa tcgaacaagg tatatggaaa gtcggagacc gtcttccttc agaaagagaa
      481 ttagcagtga aattcaatgt cagccgtatg acgttgagac aagcaattca aaacttggca
      541 gatgaaggaa tcttagaaag aaagatcggt tcgggtacat atgttgcgcg agaaaaagta
      601 caagaaaaaa tgtctggtgc aacaagtttt acagaaatta tggaatcgca aaatcgagta
      661 ccgtctagtc ggacaatctc ttatttcttg acttcgccaa gctcaagtga aatggaaaaa
      721 ctaaacttga gtaaagatga cacgatcttg cgaatggaac gtattcgttt cgcagatgat
      781 gtccctattt gttttgaagt tgccagtgtg ccacaaaagc tgatcgatgg ctacagcaaa
      841 gcagagatta ctgaatcgtt gtatcgcacg ctagaagaaa aaggcgggaa aaagatcggt
      901 ccagcgaatc aaacgattac tgctgtgttg gcttctgaga aaattgctga ctatttagag
      961 gtaaaacgag gagatgcagt tcttcgtttg cgccagattt cttattttga agacggtacg
     1021 ccgtttgagt atgtgcgtac gcaatacgta ggaaatcgtt ttgagtttta tttggaaaaa
     1081 taaaaaacag gtgatccctg attccttact tagaaataaa agagaatcag aatcacctgt
     1141 ttttatatat gatcagttac cagttgctcg tgataagaaa caggaccctc ttcaaattgg
     1201 acttgtccgt tcagcagctc aatgatggat tctttaaagt ggtcagcact tttttcatct
     1261 acagcacaga tgacgctaac ttgatcagta tattggattt cttttataaa aaaatgttgg
     1321 agttcaagat aattctgtaa ttttcctagt tgcggatacg tgatcatcac agagatctcc
     1381 tgttgcaagg taccttctac gattccaatg tcagacaatg cttgagagac agcatgagtg
     1441 tatgctcgta ttaatccgcc tgtgccgagt ttcgttcctc caaaatatcg agtgactact
     1501 gcagctacat tgatcagttg attttttttg aggacttcca acatcggtac gccagccgtt
     1561 ccacttggtt ctccatcatc gctgcttcgc tggatttcat ttttttctcc aatgatgaag
     1621 gcgctgcagt tatggttcgc tttccaatgt tcttttttta tttcttgaat gaaacttttt
     1681 gcttggtcct ctgattctat tcgtctaaga gaacagataa agcgtgattt tttgatctca
     1741 atctcacttt gtccattttc ttttattgta cgatagcgct cgatcatctt gtcacctctt
     1801 tttttcattt tctttattca gtataaataa agttctaggt tgtttcaaca ctgtaacggt
     1861 tgcgcaatcg ctgtagtatg cgataataaa gacaaaggta ggtggatctg gggatgcagg
     1921 aacgaatgaa aaagtacgat gcaattacgc attatttgaa gaacaatggc ggctctcaag
     1981 taacgttgac ctttacccaa tttgacgaac tgctgtttcc cagtaacgga cttcccaaaa
     2041 cagcaaggga aagtacagat tggtgggcaa atgattataa acaccctgaa aaaggtgcct
     2101 atggctggat aaatgcaggc tatgaagtag ttgtcatcaa tttggacaaa gaatatgtcg
     2161 tgttcaataa attagtgaaa tctagttggc tatttgatta aataaaccgc gtttagaaaa
     2221 cgttgacaaa tttctttctt tttatataat agagtaacag acgcgaagaa aacgtttgcg
     2281 tagtttgttt taaaaaggag agaaaagtat ggctaaaaaa acaatcatgc ttgtatgttc
     2341 ggctggtatg agcacaagtt tactagtaac aaaaatgcaa aaagctgctg aagcaaaagg
     2401 aatcgactcg gatattttcg ctgtgtccgc ttctgacgca gataacaatc ttgcaaataa
     2461 agatgtagat gtactgttat taggacctca agttcgcttt atgaaagctg attttgaaaa
     2521 acgtctggaa ccaaaaggca ttcctttaga cgtcatcaat atggctgatt atggtatgat
     2581 gaatggcgaa aaagtgttag atcaagcaat cacgctcata ggtgaataaa tagaacagta
     2641 taactatcga acaagcgatc caaaaaatag atcgcttgtt ttttcgtata tttttttagg
     2701 gcgaataata tgaatcattt ttggggtaga aggcttctga cgagagatat taaagcaata
     2761 gactgtgagg aggtaaattt accaaattat gagaagatcg cagcagtgga acgtttgggc
     2821 aactggattc tttgtcatcg ctgtggaatg aggacgtccg tcattgatgg acagcttgca
     2881 gattacggtt atttttgtac acattgtcta tatttagggc gatgcgacac tcaacaagat
     2941 ttatatttgt ttgatcagcc tgaagcaaaa cctcgagaag tcgtcttttt ttggacagga
     3001 cagcttactg aaaaacaaac ggaaatcgca aagagaatac tttgccattc agaaaaaaga
     3061 catcatctta tttgggctgt aacaggtgca gggaaaacag agatgcttta tcctatttta
     3121 gtggaaactt taaaagctgg aggaagagta gcgatttgta caccgcgagt cgatgtttgt
     3181 aatgaattgt ttttacgcta tcgttatgtt tttccagaag aaaaaatcac gttgctccat
     3241 gggaatacag caacggctta tacctttact tcttttgtta tctgtacgat tcatcagcta
     3301 taccgttttt atcggtcctt tgatttaata gtgatcgatg agatcgatgc gtttccttat
     3361 aacggggatg caggattagc tcatgctgtg caaacagcga ttaaaccaga cggacgattc
     3421 atctacttaa gtgccacacc tgataaaaag ttactaaagg aaatcaagca gacgtttgac
     3481 atccacaaac ttgctttgcg ctttcatcgg cgtttacttc ctgaacccgt cttggttttc
     3541 atgaataatt ggcgacaaaa atgcaagaac aagaagaaga taaaatcttt ggtgcggatc
     3601 attcatcaat taattaaaga aaaccatatc cttttatttt gtccaagtat cacgatgatg
     3661 catcgtttga aagccacact tcaagaggct cttccgagat atgagatcac agatgtttct
     3721 tcaagagaca atcagcgggc ggaaaaagtc cagaaaatgc gagaagcaaa atatgacata
     3781 ctgttaacca cgatgatcct tgaacgtgga gtcacatttg aaagaatatc cgttatcgtt
     3841 ttaggagcgg atcatccggt ttttactaaa tcttctttgg tacaaatcgc aggaagagcc
     3901 gatcgtaaag ggccttatac gaacagtcaa gtatactttt tctatgaaga aaaaactgca
     3961 gctattcgaa aagcttgtca ggaaatcaaa gaaatgaatg aagaagggaa gaagatgctg
     4021 tgaggtgcag ttgctgcagt aaagatatcg tccaaaattt aacattcagc gagattattg
     4081 gtgtttcgaa atacagatta cctcagactt gttcagtttg tcgcgcacaa tttcatttat
     4141 tggaaacaag aggctgttct ggctgtcaaa aaccaatcca tttcaatcta gagagtacga
     4201 aaaagaaagt aaagtctatt cccgtttact gcagtgactg tcaagaatgg aagaagaaat
     4261 atccgaccta tgattttcag caccgtgcct tttttgtgta cgatgaaaat atgaaggcct
     4321 ggctcaatca atacaagttt atgggagata tccgactagc aggcaccttt gcatataaat
     4381 ggacgcagat aaaaaaagaa tacccgacat acatctattg tccaatacct ttatctgaaa
     4441 aaaggcgaac agaaagagga ttcaatcaag taagcgagat gttgaaagca gcaagaattc
     4501 cttttcagat gctactcaaa agagagaagc atctgctggc tcaagcaaaa aacacgcgaa
     4561 aggaaagatt ggagatgcct caaccttttg aacttgcagt caccttttct aagatacaaa
     4621 ataaaaaaat attgattatt gatgatgtct atacaacagg acagactctt ttccacgcag
     4681 cagattgttt gcaggtcgca cagccgaaaa tcatccgaac catttcttta gcaagatgaa
     4741 ttagatgtgg aaatttgata gcgatttaat ttgcaaataa cctagagttc gatataatag
     4801 aattaagaag agggaaagag tggtccttct ccttcttgat tgtggtagac gaaaggggta
     4861 atttttatgt ttagatataa tgtacgcggc gaaaatatcg aagtaactga agcgattcgc
     4921 gactacgttg agaaaaaagt aggcaaacta gaacgctatt tcagtgacgc acccgatgca
     4981 acggcgcatg tgaacttaaa agtttataca gaaaaaacag caaaagtgga agtaacgatc
     5041 ccattacctt atcttgtatt acgtgccgaa gaaacttctc cagatttata cgcaagtatc
     5101 gatttggttg ttgacaaatt ggaacgccaa atccgcaaat tcaaaacaaa aattaatcgt
     5161 aaatcccgtg aaacgggcat gaatactgca gatgctactg ctttattcaa tgaagaggac
     5221 gaaaacgaaa atgattctga attagatatc gtacgtacga aacgcctttc attgaaacca
     5281 atggatagtg aagaagcagt cttacaaatg aacatgctgg gacataactt ctttattttt
     5341 gaagatgcag aaacaaatgg tacaagtatc gtttaccgcc gtaaagatgg aaaatacgga
     5401 ctgattgaaa cagactgatc agccttactt aaataacaac gaaaacttgc agcagctact
     5461 gacagctgcc gcaagttttt ttgagtttcc tcctctttta gatgaaatat gaataaatta
     5521 tgaagttctt actttaatac gcttaagata tttcaattat ctataactaa tgataaaatg
     5581 aaaagtaaag tctacatagt ctggataata cacagaagga aaaggagatt acacaacgca
     5641 tggccaattt gattcgttca cttatcgaaa acgataagaa agaactaaaa cgtttagata
     5701 gcattgcaaa aaaagttgaa gcatacgctg accaaatggc agcattaact gatgaacaat
     5761 tacaggcaaa aactgctgaa ttcaagggca gataccaaaa aggagaaaca ttagatcaat
     5821 tacttccgga agcttttgca gtcgtccgag aagcagcaaa acgtgtattg gggttatatc
     5881 cataccacgt acaattaatg ggtgggatcg tgcttcacga tgggaatatc cctgaaatgc
     5941 gtactggtga aggtaaaacc ttgactgcaa cgatgccggt gtatctgaat gcgttgactg
     6001 gcgaaggggt ccacgtagtt accgtcaatg aatatttagc aacccgtgac tcgacggaaa
     6061 tgggcgagct ttataatttc ttaggattga cagttgggtt gaatatcaac tcaaaatctt
     6121 cggatgaaaa acgcgaggct tataattgcg atatcactta tagcacgaat aatgaattag
     6181 gatttgacta tttgagagac aacatggtcg tttaccgtca tcaaatggta caacgtccgc
     6241 tgaattatgc cattgtcgat gaagttgact cgatcttgat tgatgaagcg agaacgccgc
     6301 tgatcatttc agggcaagca gaaaaatcaa cagctttata tacaagagca gacaacttcg
     6361 tgaaacgttt gaaagaagaa gaagattata aaatcgatat acaatcaaaa acaatcagtt
     6421 taactgaagc agggatcgaa aaagctgaag aaacattcgg tttggacaac ttatatgaca
     6481 ttgaaaatac tgcattgacc catcacttgg atcaagcatt gagagccaac tacatcatgc
     6541 ttttagacat cgattatgtt gttcaagatg gaaaagtatt gattgttgac caatttacgg
     6601 gtcggatcat ggatggacgc cgttattcag atggtcttca tcaagcgatc gaagctaaag
     6661 aaggcgtaga gatcgaagac gaaacgaaaa cgatggcgac gatcactttc cagaactatt
     6721 tccgtatgta caagaaactt gcggggatga ctggtacagc taagacagaa gaagaagagt
     6781 tcagagagat ttataatatt caagtatacc agattccgac aaaccgtccg gtcatccgtg
     6841 acgatcgacc agatttgctt tacccaacat tacaaagcaa gttccatgct gtcgtacaag
     6901 atatcaaaga tcgctaccgc aaaggacagc ctgtcttagt cggaactgtt gcagttgaaa
     6961 catctgagtt attatcagat atgctgaatc aagaacgtat tcctcatgaa gtactgaatg
     7021 cgaaaaatca ctttaaagaa gcagaaatca tcatgaatgc gggtcaaaaa ggtgcagtga
     7081 cgattgctac caacatggct ggtcggggaa cagatatcaa gctagggctt ggcgtaagag
     7141 aacttggtgg cctagcagtt atcgggacag aacgacatga atctcgtcgt atcgataacc
     7201 agcttcgagg acgtgcagga cgtcaaggag accctggtat gtcacaattc tacttgtctt
     7261 tagaagatga tttgatgaaa cgattcggtt cagaacgaat caaagctttc ttagatcgaa
     7321 tgaagatcgg tgacgaagat gctgtgatcc aaagcaagat gctgacgaaa caagtagaag
     7381 ctgcacaaaa acgcgtagaa ggaaacaact acgacacacg taagaacgtc ttgcaatacg
     7441 atgacgtgat gcgtgagcaa cgtgaagtaa tctataaaca gcgtcaagaa gtgatcatgg
     7501 aagaaaaaag cttatctaaa ccactgatga atatggtcaa acggacaatc agtcgtgtgg
     7561 tagatgcgca tacgcaatta gaaaaagaaa attggaattt ggaaagtatc gtcgattttg
     7621 ctggcagcac gcttgtccat gaagacagta tttcccttac agatatcgaa ggaaaaacct
     7681 ctcaagaaat caaagaatat ctaaacgaac gagcacaaga agtattcaat accaaagcag
     7741 ctcaattgaa cggaccagag caactgcttg aatttgaaaa agtcgtgatc ttacgtgtcg
     7801 tggactctaa atggacagat catattgatg caatggacca attacgtcag tcaatcggct
     7861 tgcgtgccta tggtcaaaac aatccattag tcgaatacca aacagaaggt tataagatgt
     7921 tcgaagatat ggtaggtgcc attgaatatg aagtcactcg tatcttcatg aaagctgaga
     7981 tccgtcaaaa cgtacaacgt gagcaagttt ctcaaggaac agcttctcac tcagaagatg
     8041 gagatgccaa agaaaacagt aatactagcg cgaaaaaaca accaatccat gtgaacaagg
     8101 ttggtagaaa tgatccttgt ccttgtggaa gcgggaaaaa atataagaac tgtcacggaa
     8161 aagatgcaaa ctaatttctg acagcaggat tggtgagaca aattcttttt taaagaattt
     8221 gtctcacctt ctttctgtta tttgacgatt ctgttagact agatataata aaaaaagtat
     8281 agtgaaagaa ggaaaaaaac atggaaatat ccgaaattcg aaatctcctg acagaaatgc
     8341 aggaaaaggt cacaagcttc aggaggtctc tttgacttag accagctgga agaagacatt
     8401 gcggaagcag aagcaaaaat ggctgaacct ggtttttggg atgatagcga agctgctcaa
     8461 aaagtgatca gtgaaaacaa tgcaaataaa gaaacttatg atcaattcca ttctcttgct
     8521 gaagaactgg aagaaatcga attgatggtg gagatgttgc aggaagaacc tgatgcagta
     8581 atgcaagaag aagcagaagc acgtatcaat gcgctagatg aaaaaatgaa tacgtatgaa
     8641 ttatctatgt tgttagatgg tccttatgat cgaaacaacg ccatcgtcga attgcatcca
     8701 ggggctggcg gaacggagtc ccaagactgg ggcagcatgc ttttacgcat gtatacacgc
     8761 tgggcagagc agcatgggta tcaagtagag acactagatt atcaagcagg cgatgaagca
     8821 ggaatcaaga gtgtgaccct actgatcaaa ggacacaacg catttggcta tctgaaatca
     8881 gaaaaaggtg ttcatcgcct tgtacgtatc tcgccttttg actcagcaaa acgtcgtcat
     8941 acttcttttt gttcggtaga tgtgatgcca gagcttgatg aaacgatcga tatagaaatc
     9001 aatccagatg atttgaagat cgacacatat cgggcgagtg gtgcaggtgg tcagcacatc
     9061 aataagacag aatccgctgt acgaatcact cacttgccta caggaacagt agtagcgagt
     9121 caggcacaac gttcacaatt gaaaaaccgg gaacaagcga tggggatgct gaaagctaag
     9181 ctttaccaat tagaagtgga aaagaaagaa caagaagcag ctgcactgag aggagaacaa
     9241 aaagaaatcg gctggggatc acagatccgt tcttatgttt tccatccata ttctatggta
     9301 aaagaccatc ggacaaacgt agagacagga aatgtccaag ctgttatgga cggagatctt
     9361 gatttattta ttgacggcta tttgaaaatg catctgcaat aagagccctt tgttaaattg
     9421 aaataaaatt gtaagatttt gcaagcaagt tgaaacattg ccatgctata atagctaaag
     9481 actgaaaaag atatggagag aacgccatga ttgaaatgaa ggatgtaatg aagaagtact
     9541 caaacggtac cactgctatc cgcaatctct cgattgtcat cgaacaagga gagtttgtgt
     9601 atgttgttgg tccgtctgga gctggtaaat ctacattcat caaattgatg tatcgagaag
     9661 aaaaagcttc aaaaggaact ttgaacgtcg caggtcatga tctaatagcc atcaaaaacc
     9721 gcgaagttcc ttatctacgc agagaaatcg gcgtggtgtt ccaagactat aaattattac
     9781 caagaaaaac agtatatgaa aatgttgcgt acgccatgca agttatcggc agaaaacctc
     9841 gggatatcaa aaaacgagta atggaagtgc tggatcttgt tggtttgaaa cacaaagtcc
     9901 gagtctttcc tagcgaatta tctggtgggg aacaacaacg tgtttctatt gcccgagcaa
     9961 tcgtaaatac acctaaagta cttatcgcgg atgaaccgac agggaatcta gatccggaaa
    10021 actcatggga aatcatgaaa ctattagatc ggatcaatgc acaaggaaca actgtcgtga
    10081 tggctacaca taacagtacg atcgtaaata cgattcgaca ccgagtaatt gctatcgaaa
    10141 acggccgcat tattcgagac caagcggaag gggaatatgg atacgatgat tagaaccttt
    10201 ttccgccatt tattagaaag tatcaagagt ttgaaacgta acggctggat gacagtagct
    10261 tcggtcagtg cggtaacgat cacgttgact ttagttggtg tgttcatggc ggtcatcatg
    10321 aacgcaacca aactagcaca agatatagaa ggaaacgtgg atgtatctgt gttcgtagac
    10381 attggtacaa aagacgaaga gatgaaaaaa ttagaaaaag aattaaatga cttagatcat
    10441 gtcaaaaaag tcgaattttc aagcaaagaa caggaattga agaaaatcca aaacgaaatg
    10501 ggcgattctt ggaaattgtt tgaaggggat aataacccgt tatatgatgt atacgtagta
    10561 agtgctaccg atccttctta tacaaaacaa gtagcagaaa aagcggcaga tttgaagaat
    10621 gtttcccgtt ctgattacgg tggggcttcc tcagatcgga ttttccaaat tgctggtgca
    10681 gttcgaacat ggggattagt tgcggcggca ttgctgctgt ttgtagcaat gtttctcatt
    10741 tctaacacga ttcggatcac gattttatct agacagcgtg aaattcaaat catgcgttta
    10801 gtaggggcaa aaaatggata tatccgctgg ccatttttcc ttgaaggtgg ttggatcggc
    10861 ttaatcggtg ccattcttcc gatactgatc attacatttg gttacgcatg gttttaccaa
    10921 ttgatcaatc cgtcattatt acgatctcat tattcattga tccatccaga aaatatcgtt
    10981 tggaaaatca atcttttgat ggtcggtatt ggtgtgatca ttggttcact cggctcgatc
    11041 atctctatga gacgtttctt gaaattctag tgtcacaaga taaatataat cagaaagttg
    11101 gacgatttcg ttccagcttt ctttttttat cagctaggtg gagtaaatgg ggcggctttt
    11161 ttctctttac tttaaaaaac aacttgggta ttcttaagtt ggtagaaaaa gaggtgaagc
    11221 cgtgaagatt atcgttgaca atttttttac gatccttttg attatgaata ttttgctttc
    11281 ctttattatc gtttttcgag aaagaaagga aactgcgcaa acatgggcat ggctgctcgt
    11341 tttgatgttc attccagttg taggatttat tttatatatt tttttaggaa gagggatttc
    11401 caaagagaaa atctttgatt tgaagatcca agggaaaatc ggtaagaacc tggaaattga
    11461 agaagacaaa caggcattga tgcgagggct ttatcctcat ccgcctactg gacaagtaga
    11521 tgtgaaacaa ttgatctata tgctcacggt atttgaaagt acgctctata cgactaaaaa
    11581 tgaaatcact ttatttacag atggtcgtga aaaattcgat gcgctgattg aagatatcaa
    11641 gcaggcagaa gaccatatcc acttccagta ttatatttat cgcagtgatg cattaggtga
    11701 agaagttcga gatgcattga cagaggcggc aagacgaggg gtaaaagtca gagtccttct
    11761 tgatgcatgg ggttccacac aagtttcttc cagctttttt cagaatttga aaaaagcagg
    11821 cggagaagtc gcatttttct ttcctctatt tgttccgtat attaatcctc ggatcaatta
    11881 tcgcaatcat cgtaaaatcg tagttattga tgggaaaatc ggatatacag gtgggttcaa
    11941 tgttggaaat gaatatctag gattggtaaa gaaatttggt tattggcgag acaatcattt
    12001 gcgtatttac ggagaagcgg tgtatacctt gcaaaaccgt tttttgatgg actggaattc
    12061 tcagcataca aaagaagtag gctattctcc caaatttttt ccgtccattc actctactgg
    12121 tgatatagct gttcaaatcg tgacaagcgg accagatacc gaacatgaac aaatcaaaat
    12181 gacttatttg aaaatgattt cgttagccaa acgggagata ttgatccaaa cgccttatta
    12241 cataccggat ggatcgattc atgaagcact gaagttggct cttctttcag gcgtaaaagt
    12301 tcatatccaa atacctaaca aaccagatca tcttctcgtt tactgggcaa cgtattcttt
    12361 cgctgcagag ctaatcgagt atggagcaag gatcgaaaca tatgagaatg gatttattca
    12421 tgcaaagacg atgattatcg atggtggcat tgtttcagtt ggctcagcaa atatcgatgt
    12481 tcgttcattt cgcttggact ttgaggtcaa tacactggtt tatgatgaac gaatggcttc
    12541 acgtgtaaga aaagcttttt ttgaagactc gaaaatttct acgcatctca caaaagaaat
    12601 gtatgaaaac cgaggaataa tcatcaagat gaaagaagga ttagcaagat tgatttcgcc
    12661 gctcctttaa aacataaaaa ggacatgaga accatcaaca gatggagatc tcgtgtcctt
    12721 ttctaacggg gccatttctg agagtacgtc agaaatggag aaagcgtctc gcatgagcga
    12781 aattaacttt ggggtatctc ttgttttttg gggaaagcaa gaaataagct aatatatgct
    12841 attaaaagag acacatttca aagccagtat agcatagaaa cttttaatga gatagttttt
    12901 tttacaatta tgagaattta ttttgttatt taatgatttt gattcgtttt catcaagtaa
    12961 tgaaaatgat aaaataaaca tactttagga ttaaaggaga tttctaatga aaaaacttaa
    13021 attattctta ccaataatag gattagctat tcttttatca ggctgttcaa agtggattga
    13081 tcgaggagaa tccattacgg ctgttggctc ttctgcttta cagcctttag tagaaacagt
    13141 tgctgaaact taccagacag aaaatcctgg aaaattcatc aatgtacaag ggggcggaag
    13201 cggaactggt ttgtctcaag tacagtcagg agcagtcgac atcggaaact ctgatttgtt
    13261 tgcggaagaa aaatcgggga tcgatgcctc agcattagtc gatcatcgag tagcagttgt
    13321 tgggatcact cctattgtga acaaggatat tggcgtaaaa gacatcagta tggaaaacct
    13381 gaaaaaacta tttacaggcg agatcaaaaa ctggagtgaa gtcggtggaa aagatcagcc
    13441 agtagttata ttgaaccgcg cttcaggaag cggaacccgt agcacgtttg aaaaatgggt
    13501 attggacgga gaaacagctg ttcaggcaca agaacaagat tcaagcggaa tggtgcgcca
    13561 gatcgttgcc gacacacccg gtgcaatcag ctatgttgct ttttcttatg tttccgatga
    13621 tgtagatacg ttgaatgtta acggtgtaga accgacagat gaaaatgtga caacgaacaa
    13681 atggacgatt tgggcatatg agcatatgta cacaagagat catccaaaaa aactgacaaa
    13741 agaattttta gactatatct tatctgatga agtacaagat aacatcgttg gagaactagg
    13801 ttatatccct gtttctcata tgaaagtcga acgtgattgg caaggaaata tcgttaaaga
    13861 gtaatcttta cacaaaattt acaaacttag ctaaactttt acatgttatt aaaaccaaat
    13921 tgatgttcaa tttgtacact gagtgagtat gttaaacctg attaaggggg agtcatctgt
    13981 ggaagatgtg aaaaaagtat tattaacaaa atcaaaacgt tcaaaaatgg aacagcgtgg
    14041 aaaattcatc agttttttat gtatcgcgct gatcgtgttg gttgtattat ctatttttta
    14101 ttttgtagct agtaaaggat tggccacctt ttttactgat aagatcaatg tatttgattt
    14161 tctgtttggt acagattgga atccaagcca aatcggagca aatgggaaac caatggtagg
    14221 ggcattgcct atgatcacag gttcgtttat tgtgaccttt ttatctgcta tcgttgccac
    14281 gccatttgcc attggtgcag cagtattcat gacggagatc tctcctaaaa acggaacgaa
    14341 gatcttacag ccggtcatcg agctgcttgt aggtattcct tctgtcgttt atggttttat
    14401 cggtttatca gttatcgtgc cttttgtcag aagtattttt ggcgggactg ggtttggtat
    14461 cttagctggt acatttgtgt tgttcgttat gatcttgccg actgtcacaa cgatgactgt
    14521 tgatgcatta aaggcagtgc cacggcacta tcgggaagct tcattagcgc ttggtgccac
    14581 aagatggcaa acaatctaca aagtcgtgct acgagcagcc gtgcccggga ttttaacagc
    14641 agtcgttttt ggtatggctc gtgcgtttgg tgaagcctta gctatccaaa tggtcatcgg
    14701 taatgcagca ttgatgccaa caggtcttac tactcctgct tctacattga cgtccatctt
    14761 aacaatggga atcggaaata caatcatggg aacagttgaa aataatgtgt tatggtcatt
    14821 agcgctgatc ttgctattga tgtcattatt ctttaatatc gtgatccgta tgattgggaa
    14881 gaaaggagag ctgaaataat gaacgcaaaa cgctcagata aaattgctac aggtgtttta
    14941 tatatagttt cggggatcat cgtattgatt ttagcagctt tactacttta tatcttagtt
    15001 cggggaatac cgcacatttc atggtccttc ttgaccgaac cttccaaagc ctaccaagaa
    15061 ggcggtggaa tcgggatcca gctatttaac tcgatttatt tgcttttgat cacgatgatc
    15121 atcagttttc ctatttcttt aggtgcgggt atctatcttt cagaatatgc tggaaaaaac
    15181 tggctaacag atgtgattcg cacgtcgatt gaaatcttga gctcattgcc ttctgtcgtt
    15241 gtcggtttat tcggtttctt ggttttcgtt attcaattcc agtatggttt ctcgattatt
    15301 tctggtgcat tggctttgac tgtattcaac ttgcctcttt tgactagaac agttgaggag
    15361 tctttacaag cggtccatta cacacaacga gaagcaggat tggccttagg tttgtcacgc
    15421 tgggaaacag tgataaaagt ggtggttcca gaagcgacac cagggatttt gactggtgtg
    15481 atcctaagtt ctggaagaat ttttggtgaa gcagctgcat tgatctatac ggctggacaa
    15541 agtgcacctg cgttagattt tacgaactgg aatccattaa gtgtttcaag cccgatcagc
    15601 attttccgtc aagctgaaac attagctgtc catatttgga agatcaatac agaaggcacg
    15661 atgcctgatg gtgtttctgt ttcggctggc gcttctgccg tgttgattat tgctgtttta
    15721 ctgttcaact tcggcgctcg tgcgattggc aaacgattat accgaaaaat gacttcagcc
    15781 taaggagaag aagcaaaatg aaaaaatata actggaatga aacaaatgtc atcaccatgc
    15841 caaaagagaa agaagtagca ctatatacgg atgatctaca tgtctggtat ggcgacaatg
    15901 aagcaatcaa aggagtggat ctggaatttg aaaaaaataa gatcactgca ctgattggtc
    15961 cttccggctg cggaaaatct acgtatcttc gttcgttgaa tcgaatgaat gatgggatcg
    16021 ctaatacgaa aatcactggg aaaatcatgt atcaaggcgt agatattaat gcgcctcaag
    16081 tggatgttta tgagatgcgc aaacggattg gcatggtttt tcaacgtcct aatccgttca
    16141 gcaagtcgat ttatgacaat attacatttg ctttgaaaca gcacggcgaa aaaaacaaaa
    16201 agaaattaga tgaaatcgtt gaaacaagct tgaaacaagc tgccttgtgg gaccaagtaa
    16261 aagacagctt ggacaaaagt gccttggctt tatctggcgg gcaacagcaa cgtttatgta
    16321 ttgctcgtgc gatcgcgatg aaacctgata tcttgctgct agacgagccg gcaagtgctt
    16381 tggaccctat ttcgacagga acggttgaag aaacacttgt aaacttgaaa gaagactata
    16441 cgatcatcat cgtgacgcat aacatgcaac aagcagctcg tatcagcgac tatactgcct
    16501 ttttctattt aggaaaagta atggaatatg acaaaactaa caagatattt accagaccaa
    16561 aaattcaggc aaccgaagat tatgtgtccg gtcattttgg ttaagacgga ggcctcaaca
    16621 tgacaaaaga gattatttca tctaaagatc ttcatctgta ttatggaaag aaagaagcac
    16681 taaaagggat cgatctaagc ttcaatcaag gggaaatcac tgcgatgatc ggtccttctg
    16741 gttgcggaaa atccacttat ctgcgttctt tgaaccggat gaatgacctg attccgaatg
    16801 taacgatcac cggaagtgtt ttatataaag acaaagacat ctatggtcca aaaacagatg
    16861 ttgttgaact aagaaaagaa atcggcatgg tattccagca gccaaaccca tttccttttt
    16921 ctatctatga aaatgtcatc tatggattga aattaaaagg ggaaaaagat aaaaaagtcc
    16981 ttgatcaagt agttgaagaa agcctgaagg cagcgtctgt ttgggatgat gtgaaagaca
    17041 aattgcataa aagtgcttta tctttatccg gtgggcagca gcagcgtgta tgtatcgcac
    17101 gtgttttggc agttaatccg gaaatcatct tattggatga accaacaagt gcgcttgatc
    17161 ctgtttctac tgggaaaatc gaaagtatgc tgttagaatt aagagagcgg tatacgatga
    17221 tcatcgtgac ccataatatg tctcaagctt cacgtatttc agataagacg gcattctttt
    17281 tagatggtca cttgatcgaa tacaatgata cgaagaagat attcatgaat ccagaaaaac
    17341 aagagacaga agattatatt tcaggtcgat ttggataagg aggaaacgga atgctacgta
    17401 cacaatttga agaagaattg ctgaatctcc ataatcagtt ctacgaaatg gggatgatgg
    17461 tgagcagcgc cgtgcacaag tcagttcgtg catacatcaa acacgataaa atcttagccc
    17521 aagaagttat cgaaaacgat ataaatatca ataacatgga aacacgcttg gagaagaaaa
    17581 gttttgaaat gatcgcattg caacagccag ttacaactga tttgcgtatg atcattacgg
    17641 tcatgaaagc tagctcggat ttagaacgta tggccgatca tgcggtgtct gttgctaaat
    17701 ccacgattcg cgtaaaaggg cagacgagaa taccggaaat cgaaaaagag atctccgata
    17761 tgtccgatta tgtgaaaaaa atggtggaca acgtcctagt tgcttatgtc aaaacagacg
    17821 aaaaagacgc acgtacgatc gccaatatgg atcaaagagt caatgactat ttcaatcgaa
    17881 tctataatgc aacaatcaaa aatatgcagg aaaatcctga gacagtcatc agtggaacag
    17941 actacttgaa tgttgccagt tatctagaac ggatcggaga ctatgtgaca aacatctgtg
    18001 aatggatcgt ctacttggct acagggaaaa tcactgagtt aaatacgaac cacaatgaga
    18061 ttttctaaac tgaagctgtg attatgccgt ttgtttagga aaagaggttg tgaaatcagc
    18121 ggttgtgaaa aagctgttct gcatcaagta ataagaacag tcaaacaaaa aatagctcct
    18181 catatttttc gtttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    18241 cgggaaaggg tttgtgacaa aacatgtcac aaaccctttt catcatttca tagaaaggat
    18301 aaagaatgca aaaaaaaatt agcatcatca ctatattttt tatttgtgtg cttacttcat
    18361 gggttattca gcatcaagcc gctttatatg aagtacctgt catcgagata gaaaaagtac
    18421 gaataaaaga ggatcatcaa ttgattacag gaaaactgat gaacacggat caaaaaggag
    18481 aatcgattta tttatcggtt ccttatcaaa aaaatcaaat agaaacagca aatataaaag
    18541 cgagacaaat gtatctagtc caaatgcatg gagatgaatg gcagctagta gcaaaaaaaa
    18601 atgatggctg gcttttcttc ttcacaagta tcttcattgg cgccatgttg cttattggtg
    18661 gaaaacaggg tctatttgct ttaggaagtc tcatcatcaa tatcgtttta cttttacttt
    18721 tgttgctcat ctttactaaa acagaaggga tttctctatt aaatatatct atcctgttcg
    18781 tcgttatagg gatgattatt agcatattgg ctttagatgg atggaataga agcagtataa
    18841 tcaaaatttc agctgcagtt acgagtgttt ttttagcatt ttttatttgt cttttgacaa
    18901 tgaatcattg gaaagaccaa ggactgcgct atgaggaact gaattatctg acacgaccgt
    18961 atcgttctgt ttttctttct agcgtactga ttggaacagc tggaggaaca ctcgataccg
    19021 ttatcacagt cattgcgaca ttagaagaat tgactaagcg acaaccagaa ataacagcga
    19081 aacagttatg gctttcagga aggcaagtgg gtcgagatgt gattggctcg atgaccaata
    19141 tccttttgtt cgtctatatc agtgggtcag ttccatcgct tcttttatat ttaggaaatc
    19201 aatggtcgtt caaagaaacg atagaacagc atttatcatt ggaattttta cgcgtcattg
    19261 ctggcagctt aggaatagta ttatcgatcc ctatctcggt cctctttttt ctgactgtaa
    19321 ggaggctgaa acgatgaatg tacttattat acttgttggg attttagcaa tcagcgtgct
    19381 acttattggc ggtacgcaag gtatgtatat tcttttaggc ttattcatca atttagggat
    19441 ctttttcctg ttgttattcg gttatcatca gaagtggccg atactggcat tgtcggtcat
    19501 aggattttta ttgattgctg tggttatctt attttttatc aacggttata atctaaaaat
    19561 gcgtgcagct tttgtgagta tactgatctt tttattttgt ttcctactat tgcttcctat
    19621 cactgatttt ttagcaatcc aaggttttac atcggtagaa ctagaagaat tatctggctt
    19681 agataagact ttagcgattg attttagatt acttacgaga tcgttgcttc tgattagtct
    19741 tagtggtgct gttttagatg cgagtgtagc aatttctagt gggacattcg aagtatatca
    19801 ggcaaatccg caattatctt tttaccaatt gcgccattct agtttcgcta ttgctaaaaa
    19861 aatattggcg tcaacagtaa tgacacttct ttttgcattc atgggaagtt ctttagcgtt
    19921 gatcctctgg tttattgatt tagacattcc ttttcagcaa gtgatcaatg aaaaatcatt
    19981 tgttctagaa tatacgatgg ctattcttac cacattgtcc gcactacttg ttcttccttt
    20041 aacctgcgtg actacagcat atctctttac aaaaaagaaa gaacaactca agatggagta
    20101 aaagttacaa cttaagtcct atgacatttt tactgaatca gtgcataata tggatgtaag
    20161 gaaaagcttg caaacaattt tgcttaagga ggcaatttcc atgaaagaaa gagaacgtat
    20221 tttagattta gtgaaaaaag gaatcctttc gactgaagaa ggcttagatt tattagaaag
    20281 catggcaact gaaaaagacg aaaagcaaat caaaaaagaa gcagacaagg taactgctag
    20341 tcataaagaa aaagatcagg caagtcaatt gatcgataaa cttgaaaacg gcgaagaaga
    20401 aatttctgag ccagttgatc caaaggaaag agaaagacaa gatcaagaaa acttagaaaa
    20461 gatcttagat gaactagcaa ctgaagcgaa taaaacttcg gcgcgtctag atgaagtaaa
    20521 tgctcaattc gctgacaata aggcagcacg caatgagaaa caggaagcat tgatgcagct
    20581 gaatacaaaa gaagaattag gcgagttgac agaagaagaa ttagcacagc gtcagacgtt
    20641 agaagcagaa atcaaagaat tagaagctag tggcgataca ctgttagaag aacaattgaa
    20701 attagaagca gaattaaaag atatccgtaa gaatcaatgg tctgagaaaa aagaaacgtt
    20761 tactgataag tttgaattgc cagatgattg gaaagatcaa gcaacagata cactgaatca
    20821 agtaggcgaa aaaatgtcag aagctggatc acagttaggc aaattcttga agaaaacatt
    20881 ccaaactgtt tcagaaacag tgaatgacaa catggaatgg aaagatgtca gcttacgtgt
    20941 ccctgggatt gcgacaacga aatttgagca tgaattttac tatgaagctc ctgcagcaag
    21001 tatccttgat atcaaggcag caaacggaaa cgtgacgtta aaaacgtggg acagcaacga
    21061 tgtgaaagtt gaagctaaga tcaaacttta cggaaaaatg ggtgctgaac catttgaagc
    21121 attctctgaa cggagccaga ttgaggttaa tgaagatcat atctccttcc aaattccaaa
    21181 taaacgtgtg cgtgcagacc ttgttttcta cttacctaaa cgagtatacg accacgcagc
    21241 tattaaactt ctaaatggca acatcatgat tgaaacattg gaagctaaag atatttatac
    21301 aaaatctacg aatggtaaca tcatcgtgga ccaattaact gcaacgatgc tggaagtaga
    21361 aggtgtaaac ggcaatatcg atattcgaaa cgggaacatc ttagattcta ttatcgaaac
    21421 agtaaatggt acagtgacat ttggtgcgac agcagaaaac ctttctgtgt ctttggtaaa
    21481 tggtgatgta cgtcttacga ttaaagaaga taatttgaaa aaagtagaag caagttcagt
    21541 gaacggaaat gtcaaagtcg ctttaccaga tggcatcggt ttggaaggac atgctaaaac
    21601 aagtcttgga agtatcaaca gccgtctgtc caattacgaa gtagttcgtg agaaaaaaga
    21661 acggacaaac caaatgttgc aattccgtcg tgtttcagat ggtgaaatcg cgcaagtgca
    21721 actttcaacg acaacaggaa gtatctattt aaaagataca gataaataaa gaggttgtga
    21781 aagagatgtt cagccttgag caataagaag cgattttgta aaatagcttc ccctatttta
    21841 caaaattgtg ccttattgcc gatagtctat ctcttgaaca ccgtttacca agagattatg
    21901 aacctgccaa ttatcgccga gtcacaagga ataatttcag aaaaagctcg tcacgtttta
    21961 tgaatatggt aatttgtgac cgagaatttt gcagaaagac accgattaag aagaaggttg
    22021 tcacaacgat tttcttcatt taaaatagta gaacagaggt gagacatgat gaaaaaaaag
    22081 ttgacaaaat ctaataaaaa tgttgttttg acagggactt tagcaggaat aggagaatac
    22141 atcgggattg atccgactgt tatccgtgtg ctttatgtat tcctgagctt agttgctttt
    22201 ggaagtccaa ttattttata cattttatta gctttgatta tcccatctgc gcgttctgca
    22261 cgaacaaact atggacataa caatgcatat tatgaaaaaa acaattatcg tgaacaaact
    22321 cgtgaacaaa caaaaaaacg caaagaagcg gaaaaaatcg atgatgacga atggagtgac
    22381 ttttaatgtc gtactttcaa cgtattttag ttaatacgtt aacattcata tcattggctg
    22441 ttctttttcc tgcgatggtc catgtgagca gtatttggac ggccgttctt gccagcttcg
    22501 tattgtctgt gttgaatatg tttgtcaaac cgattttgac gatactgtcc ctgcccttta
    22561 cattagtcac attgggattg tttacgtttg ttatcaatgc agcgattctt aaaatgacct
    22621 ccttttttgt gggagcagaa cattttagtt tttcttcatt cggtgcagcg ttgttagtag
    22681 ctatcttgat gtcgcttgtc aatgtaattg tcagcgaaca taacagtaga aaataaaaga
    22741 aagctgtgcc gaactatcgg cgcagttttt ttatttagaa tcaggaatgc gttttctatt
    22801 acattggtaa ttaaataaaa acgttttttt taattggtag tacttttggc tagacaatga
    22861 taaaatgata gagaacactc taatagaaat gaggtagcat gaatgtcaga agttgtaaaa
    22921 gttagccaat tagtgaaaaa attatctttg gaaatcgtga caggcgacga gaaaagctta
    22981 gaccgtgtca tcgtaactgg ggacatctca cgcccaggac tagagttgac tggttatttt
    23041 aattattatt cccataatcg tttacagcta tttggcagta aagaaatcag ttttgcggaa
    23101 cggatgatcc cagaagagcg tttgatcatc atgagaagat tatgtagtga agatatgccc
    23161 gcatttatta tttcaagagg attaccagct ccagaagaaa tgatccaggc agcaaatgaa
    23221 aatgggatag ctgtactgcg ttctcccatc tcaacttctc gtttattagg agaattatcc
    23281 agttatttag atggtcgcct tgcccctcga acaagtgtcc acggtgtttt agtggatgtt
    23341 tacggattag gtgtactgat tcaaggtgac agtgggatag gaaaaagtga aacagcgttg
    23401 gagttgatca aacgcggcca tcgattgatc gcagacgatc gagtagatgt ttatcagcaa
    23461 gatgaattaa cggtgatcgg agaaccgcct aaaatcctgg aacatctgat tgaaatccga
    23521 ggaatcggga tcattgatgt aatgaatctt tttggtgcga gtgcggtacg tggctctatg
    23581 caagtccagt tggctgttta tctggaagca tgggcaaaag ataagaaata cgaccgtctg
    23641 ggctctgaag acacgaccgt tgaaatcgcg gaagtgggca ttccacaaat aaaaatccct
    23701 gtcaaaacag gacgaaacgt tgcaatcatc attgaagtag ccgcgatgaa tttccgtgca
    23761 cgtacaatgg gctttgacgc aacgaaaaca tttgaagaaa gattaagtcg cttgattgaa
    23821 gaaaactcag gcaacgacta gcaaggagtg acaatatgtt agcacaaatc aatcgagttg
    23881 cttttgagct tgtagggatt cctatctact ggtatgcatt gatcatcgta tcaggtatca
    23941 ttatcgctat gtggcttagc agcagagagg ctgttcgggt aggattaaaa gcagatgatg
    24001 tgacagattt tatgttgtgg ggattgccta tctccattat tggcgctcgc ttatattatg
    24061 ttttatttga tcttccccag tatatagctg atccaatcca aatattcaat atccgttcag
    24121 gaggcttagc tatttatggc ggactgattg caggcgcgat cacgctgtat ttttttacta
    24181 aatatcattt tatttctttg tggacttttt tagatatcgc tgcaccaagt gtattattag
    24241 cacaggcaat cggtcgttgg ggaaatttca tgaaccacga agcatatgga ccagacacga
    24301 cgcgaagctt cttagaaagt ctgcatttac cgcaattcat cattgataat atgtatatcg
    24361 aagggatcta tcgtcaacca acatttcttt atgaatcact ttggagtttg attggattta
    24421 ttttgctttt gtttttacga aagaaaccac accttttgaa aaaaggcgaa gtccttttat
    24481 gttatctaat gtggtatagt ttcgggcgtt tctttattga aggattacgt acagacagtc
    24541 tttacttttt aggtgtgatc cgtatttctc aattattatc tgctgtgtta tttgtcggta
    24601 cattgattct atttatttgg cgcagaaaaa aaggaaattt accggattat gaccgctcat
    24661 taggaaaaaa tcaacaaatt atctgatttt tagagcgtta aaaatgaaaa aaatttcagg
    24721 agtggtaaaa tgaattatag agtagcggtt ttaggaccag gctcttgggg tactgctttg
    24781 gcacaagtcc tcgccgaaaa cggacatgac gttcggattt ggggacatcg tgcttcacaa
    24841 gtagaagaaa tcaacaccca acacacgaat caacgttatt taccagatca ttatctaccc
    24901 gattccatcc aagcattcac caatatggaa gatgcagtaa aagacgcaga tgcggtgcta
    24961 ttcgtcattc caacgaaagc aatacgttct gttgcaaaag aactagtgcc taaattgaat
    25021 acaaagccag tgatcatcca tgcaagtaaa ggattagaac agggaacaca taaaaggatc
    25081 tctgacatct tgttagagga aatcccagca gaaaaaagaa aagctgttgt tgttctttct
    25141 ggaccaagcc atgcagaaga agtagcaaaa catgacatca ctacgatcac agctgcaagt
    25201 acagatgcaa aagcagcaaa atatgtacaa gagctgttca tgaataatta ttttcggatc
    25261 tataccaatc ctgatgtgat cggtgtagag atgggggcag ctttgaaaaa tattattgct
    25321 attggtgctg gcgctattca cggcttaggg tttggcgata atgcaaaggc agcaatcatg
    25381 acgcgcggat tagctgagat cagccgttta ggtgtagcaa tgggtgccaa cccgctgacc
    25441 tttatcggat taagcggaat aggcgatcta gtcgttactt gcacaagtgt tcattctagg
    25501 aactggcgcg caggcaactt gttaggacaa gggcagcccc tagaagaggt gctagccaat
    25561 atgggaatgg tcgttgaagg tgtgaatact acccaagcag cgatggaact agcccaaatg
    25621 atggaaatcg aaatgcccat cactcaaaca atctatgaag tgctgtatga acaaaaagaa
    25681 atcaaaacag ccgcaaaaga aatcatgtta cgtgatggaa aaaaagaaaa tgaattctca
    25741 ttaacaattt tttgaaggag cgaatgtata tgaaagttaa aaaagcagtt attccagcag
    25801 caggattagg aacaagattt ttaccagcaa caaaagctat ggcaaaggaa atgttgccaa
    25861 ttgttgataa accaacaatc cagttcatcg ttgaagaagc gttgaaatca ggtatcgaag
    25921 acatcttgat cgttacagga aaagctaaac gaccaatcga agatcacttt gattcaaata
    25981 ttgaattaga aacaaaccta agtgaaaaag gaaagaccga attattgaaa ttagtagaag
    26041 aaacgacaga tgtcaacttg catttcatcc gtcaatctca tccaaagggt ttaggacatg
    26101 ccgttcttca agcaagagcc tttattggaa atgaaccatt tgtcgttatg ctaggcgatg
    26161 atataatgga agacgaagta ccattgacac agcaattaat cgatgattac gaacgtactc
    26221 atgcttctac gatcgccgtt atgcaagttc ctcatgatga aacttcaaaa tacggaatta
    26281 tcaatccagg agaagtattg gaagatgggt tatacaatgt caaaaacttt gttgaaaaac
    26341 cagatccaag caaagcacca agtgatttag ctattattgg acgttactta ttgactccag
    26401 aaatttttga tgtattgtcc gagcaacaac caggagccgg aaatgaaatc caactaactg
    26461 acgcaatcga tacattgaat aaaacacaac gcgtatttgc ccgtaaattc acaggtaaac
    26521 gttacgatgt cggtgacaaa tttggtttta tgaaaacaag tattgaatat ggtctaacac
    26581 atccagaagt aggtgcacct ttacgtgagt acatcctgtc tttaggtaaa acattagaag
    26641 cagaaggaag caagatcgat cataatccaa aaggaataac agaaatcaaa gaagaaaaga
    26701 aaaaataacc cttttttcta acgagcttca gctgctaatt gaataaaaag tagttgaagc
    26761 tcgtttttat ttgtttaaaa aacacgaaaa tgctatcctt atagaaaaga gagacaagaa
    26821 gggagtttga tcatgtcagg aggagaaatt gcaggattga tcgcagcaat cgcctttgcg
    26881 atacttgtcg tttttatcgt tcgtgtgttg ttgcaagttt ctaaaacttt agaaaaagta
    26941 gatcagactg tagcagaagc aaatacgacg atcgaaatcg tcacaaaaga cgtagatctt
    27001 ttgtctagac aagtagaagg cttactggtc aaaagtaatg aactgctctt ggatatcaat
    27061 ggaaaagtcg caacgatcga tccattgttc acagcagttg ctgatttaag tgaaagtgta
    27121 tcagaactta atcattctag taaaaacatc gcgacgaaag tcggcggaat cggtaaaacg
    27181 acagctaaag cgacggttgc cggaaaagtc ggtgggacag cgatgaaatt ttttaaaaac
    27241 aaaaaacata ctgaaacgac aggaggaaaa taaaaatggc taaaaaaggt ggatttttat
    27301 taggtgcagt agtcggaggc acagccgcag caatcgccgc gttattgtta gcaccaaaat
    27361 ctggtaaaga acttcgggat gaattagctg cccaagcgga tgatttgatg gatatggctt
    27421 cagattacac agatatggcg aaagaaaaat cgactgagtt aacaggtatt gcaaaagaaa
    27481 aagcgcaaga tctttctcaa caagcaggtg atctagcagg tagtgtcaaa caaaaagtaa
    27541 gtgaatcagc agatgaagca ggaagtgaat ctgacgatat cttgttaaat cttaaagaac
    27601 aatcagctga cttatctaat cgtttcaaaa aaacggcaga agatatgaaa aaacctgcag
    27661 atgaattagg aagtattgct aaagatactt cagaagatat catgattgat gtaaaagacg
    27721 ctgctggtaa agcaggagat actgtcaatg aaggaatgtc agaagcaaaa ccagttgcag
    27781 atgactcaaa agaaatgatg aaaatggcaa aagaagatgc gaaagaagct aaaaaagaaa
    27841 taaaagatac aatgacagat tcatctacaa atcactaaaa tcacaaattt atagaataaa
    27901 aaggtgggag cggactagct ctcacctttt ttactcttat ttttctaaaa caagtaattc
    27961 ttttggtgta gtcgtgaatg gcacacagcc atcgcttgtc acatatacac agtcttcgat
    28021 acgtacccct actttttcag gaatatagat tcctggttca agagagaagc acatcccttc
    28081 ttcgattact aagtcatttc cttctacaag ggaagggaat tcgtggacgg ttgttccgat
    28141 cccgtgacct aaacggtgat tgaaatattc gccgtagcca tagctgttga tcacgtttcg
    28201 tgcgatttga tcaagttcac ctgctgtcac acctggacgg acggcttctt gtgcggcaag
    28261 ctgtgcttca agagtgatgt tgtagatttt ttcttggaag tcggttggtt tttgataagc
    28321 aattgtacga gtagcatcac tgcaatagcc attccaaaca acgccaagat cgaataacac
    28381 aagttcattc ggtgaaatct tcgtatttcc tggtgtacca tgagggcttg cagcatttgc
    28441 tcctgcaagg actaatgtgt cgaaagacat ttgtgaaaca ccttgttttt tcaattggta
    28501 ttcaatttct gcaatgatcg cttgttcagt cacgccttct ttcactgctt taaagccaat
    28561 ctcaaatgca acatcggccc atttaccagc ttcgatcagt ttgtcttttt cctctagagt
    28621 tttgatcagt tgtagacgtt ggatgatgga agttagatca gtgtaagaat ccgttcccgt
    28681 caagatatca gagatagcat cgaagcgctc gacagtcaag gcgttctttt caatccctac
    28741 attgccaggc tgaccatagc gagcacgaag ttcttttccg atgatctccc aagggttttc
    28801 gctgtctaaa tagccacgga catcatacgc ccaactactg ttttgagcat cttcaacttc
    28861 caaagcagga gtgaaaagga aaggatcttg ttcaagaggg ataaaaagag ctagtacacg
    28921 ctcatgagga tcactttcgt atccggaaaa gtaagcgatg tggccagggt cgctgatata
    28981 agccaattcg acttggtgtt gtgccatcca ttgacgtagt tcattgattt ttacgttatt
    29041 catttggcaa cctactttct aaattaattt tgtattcaat aattgtacca ctgatttatt
    29101 aaaagaccaa cgttctaaaa actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa
    29161 cggttgcaat tcttgagatt atttgatatt ctattttaga aatgtaagac gtattttcag
    29221 aaaacatata aaatatgaat aggagaacac aaatggaaaa gcaaacaatc actatctatg
    29281 atgtagcgag agaggcaaat gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc
    29341 caaacgttaa accagcaaca agaaaaaaag tcttggaagt tatcgatcgc ttggattatc
    29401 gtccaaacgc agttgcgcgt ggcttggcaa gtaagaaaac aacaacagtt ggtgtaatca
    29461 tccctgatgt cagcaatatg ttctttgctt ctttagcacg tggtatcgat gatgtggcaa
    29521 caatgtacaa atacaatatt atcttagcaa attcagatgg caacgaccaa aaagaagtca
    29581 atgtattgaa taacttactg gctaagcaag tggacggcgt gatcttcatg ggtcaccata
    29641 tcacagacga aatccgtgga gaattttcac gttcaaaaac tcctgttgta ttagctggct
    29701 ctattgatcc agatgaacaa gtaggtagcg taaacattga ttatgtatcc gcaacaaaag
    29761 atgcagtaaa caaattggca aaaagcggca ataaaaaaat cgcttttgtc agtggtgcgt
    29821 tgatcgatcc catcaatgga caaaatcgtc tgaaaggcta taaagaagca ttaagcgaaa
    29881 ataacctacc atatagcgaa ggattgatct ttgaagcaca atacaacttc aaagatggtc
    29941 tatctctagt cgatcggatc cataatagcg gtgcaacagc tgtctatgtt tcagatgatg
    30001 aattagccat cggtattttg gatggtttat tagaccgtgg cgtgaaagta ccggaagaat
    30061 tcgaaatcat cacaagtaac aattcactac tgacagaagt agctcgtcct cgtttaacaa
    30121 gtatcacaca accattatac gatttagggg cggtatctat gcgcctattg acgaaaatga
    30181 tgaataaaga agaagtcgaa gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag
    30241 gatctacaaa ataataaaag gacaaccatt cagaggttgt gtgcctgccg tttaactctg
    30301 cgttacaagg agcaatttca aaaaacagca tctcatgttt gatgaatatt gtgactcgtg
    30361 attcggagtt ggcaggagaa caccgtttat ttgggaaaag gggttatgac aaaattttgt
    30421 tataatcctt tttttgtgtc ttaaaaaaga gagaaagtgg ttgaaattac atttatcgta
    30481 tataaaacaa tccgtgtata gatgctgcat tttgttcacc accatcaaaa aaataaggga
    30541 ctgtgacaat actattgtca caatccctta ttactgtgta ttctattaaa tcaatcatct
    30601 ttctcatctg attctttagt tgcttgattc gctcttgcat aagctgaagc ggtgttccag
    30661 taatctgtat agttttcatc ggtaccgcca acgccaaatt taaaggcgct tttcttcggt
    30721 ccatttttcg cccatagcga ttcaactgtt tttcctggtg tttggatgga ttttttattg
    30781 acagtaactt ttccaggtgt ttgaccagta aatccagata cttttttctt catcacatca
    30841 gatgataatt cgaatttctc atcagtgcca aaaatgtcag gttttgcttg gtaagcttga
    30901 ttgatcagat tggcaagata attagccgaa cgtatccttg ctttgctgtc cattccagta
    30961 ttgtcatcgt gccctgccca gctactgatg gtaatagacg gagtagagac aattagccat
    31021 gaatctcggt attcattggt agaaccagtt tttccgaccc aatctgcttt tcctagattt
    31081 ccgtttaagc ttgagatggc atctttgaat ggtgtagtga tttttgcatt gatcacacta
    31141 cgcatcatgt cattcatgat cgatgccgtt gcttccgaat agatccggac agagttgctt
    31201 tcgtgtttat aaattacatt tcctgcgtta tctgtgatgg aatcgatgat atagccttct
    31261 tcatagacgc cgccgtttgc taaagcctga aatccgttgg tctgttgaag cgtcgtgaca
    31321 tctactgtac ctaaaggagc agattcaacg ccccaattgt catttgccgg gtagttcatc
    31381 tttgccaagt agtgctcgta agcatattgt ttcgatccac cggaattcaa cacatcttga
    31441 tataagtgat aagccgggat attgttggac cattctagtg actcacggac ggtttggaag
    31501 gtgttcgatc cttcgttagt agcattgacg attttctcgc cagcattttc tccttcttgc
    31561 caagttgttg cataatctga tacacgggat tctgatccga taagccccat gtcgattgca
    31621 ggtccataaa caagaactgg tttgattgat gagccagctt gacgttctgt atcgaaggca
    31681 tggttatttt gattctgact gtaattccgt ccgccaacga atccgtagat gcggccagtt
    31741 ctgttatcca tcaatacatt tccggtttct acttgactgc cagcaccatc atctaacatg
    31801 tatccataat tttcaacgcc attttgcaat gcagcataga catctttatc gattgtcgaa
    31861 tggattgtat atcctttatt ttggatcgtt tgctgtgcct tttgataata agcgtcactg
    31921 accgatgaat cagacatatc agcgttgtct ttttcagcca attgttgtgc aatgattctt
    31981 gttgcttcat tcatcacagt ataatacaag aattctctgt cagtctgttc tgcgatttgt
    32041 tgtggtagaa agtcttttgt aaggtcatag gcttttgctt cttcgtattg ttctttcgta
    32101 atttggcctt cacgatacat actgaataaa acaaaatctt ttctggcaag gccggcagaa
    32161 agatcttctt ttagcgcgcc tgtgttcgtg tatggactat acgtgatcgg gctttggggt
    32221 aatccagcga tataagcagc ttgcggcagc gtcacatctt ttgcatctac accaaagatt
    32281 ccttttgcag cttcctggac tccagcaatg ttttgtccct tattattacg accaaatggt
    32341 gagacattca aatacgtagc aatgatctca tcttttgaaa agtatttttc tacttgtgca
    32401 gaaagaatga tctcgtttgc tttacgtttg aatgttgttt catctgtaag gatctgctgt
    32461 ttgactaatt gctgtgtcaa agttgatcca ccagaagagc caataccagt agcttcagat
    32521 actaatgctc gtaaaacagc tttaggaacg taaccttggt gtttatcgaa gtattcatcc
    32581 tctgtgctga taattgcagt tttcaataaa ggtgaaatct tatcagatga aatagtcgtg
    32641 cgcatcagat ctgtctggat ttttgatatc tctgtattat ctgcataaac aatctttgac
    32701 gtttctgtaa tgtttcctag ttctgtctgc agtgcttttt tagtcggcaa ttgtgtgtct
    32761 tcgacgagat aggcaaaata gccagcgcct attccaatac ctagagctgc gaacatcaaa
    32821 agaagaacag taataaaaac agtcaatgat tgaaaaactc taaaaataat cttaggaaca
    32881 aaccattttt ctttttttct tctattctgt ttttttcgag tatttttgcg tggcaaaagg
    32941 gtcacctcaa ctaatggttt tatttcgcta attatagcaa ataatagaac aaaaaaacag
    33001 acaaggctgt ttttggcagg aatttctttt ttaaaagagt taaaacgtga gaaaatgatc
    33061 tttattataa aagagttctt aagcttttct ttagagaaaa tttcagttac tatggagaac
    33121 agggcaaaga aaaatcaatc attttctttg tatatcatct taccaatata taggaattgt
    33181 tagtaacaat tgcctttcaa ggaggaatcc atccatgtta ttaggctcac acgtcagcat
    33241 gagcggaaag aaaatgctgt taggagcagc agaagaagca gccagttatg gatcttcgac
    33301 ttttatgatc tatacaggcg cccctcaaaa cactagaaga aaagccatcg aagagatgaa
    33361 tattgatgcc ggaaaagcgt acatggcaga aaaaggtcta acaaatatcg tcgttcatgc
    33421 cccttatatc attaatttgg ggaatacgat caaaccagaa atgtttcctt ttgccgtcca
    33481 atttctgaga gaagagattg ttcgtgcgga agctttaggc gctactcaaa ttacacttca
    33541 cccaggtgct catgtagggg caggaacaga agccggaatt gctagaatta ttgaaggctt
    33601 gaatgaagtt ttgacaaaag aacagacggc acaaatcgct ttggagacaa tggcaggtaa
    33661 aggtacggaa atcggtcgaa catttgagga attagcgcaa atcatcgatg gagtaaaatt
    33721 gaatgaaaaa ttatccgtta cttttgacac ctgtcatacg aatgatgccg gttataatat
    33781 taaagaagac ttttcaggtg taatggaaga gtttgataag atcatcgggt tagatcggct
    33841 taaagtactc catatcaatg attctaaaaa tccgcaaggt tcgcataaag accggcacgc
    33901 caatattggt tttggaacaa tcggattcga cacgctgaat aagatcgtcc atgatccaat
    33961 gtttgacaat atttcgaaaa tcttggaaac tccctatgta ggcaaagata aaaagaaagc
    34021 ttacgcacca tatggaaaag aaatcgccat gttcaaagcg caaacattcg atccagaagt
    34081 gtttcctgag ttattagcag aagaagtgat actctaagat tttctatctg acagcagcaa
    34141 aaaaggacca ggcacattgc cttgtccttt tttgtttaag aaacaaagga gtactttttg
    34201 cagtcttttt catcatgcat cttctccccc ctctttttaa atttagacaa acaaggtata
    34261 ctggtagaaa agtaaaaaaa cgaaaagttt cacaagcaag tggcaaaacg tgattggaag
    34321 gacgaaaaga tgctgaacac tttaaaaccc ttgatcaacc aactaaaaaa gaaacataca
    34381 tactttattc ttggcatagc cctattattt acaattattc gtttgtattt atatagtaaa
    34441 gcaatctatg gaacagacat gtcggcaacc tatgatgacc agctgctgat tcgctatgct
    34501 caaaatattt tggacggtaa atggctaggg gagtatacga ctacaacact ttccaaagga
    34561 atctcctaca gcttattttt agtacttgca cataaactgc atctttctta tgcagttttg
    34621 ttcggcatgt tcagtatttt tgccagtata ttggttgcac tcgcgtttaa accgattgtg
    34681 aagaacaagt atcttctttt aagtatctat ttttattttt tgttttctcc gattagtttt
    34741 acacatgaat attccactcg aacatatcgt aatgccctcg tgattccggc tgttgagatc
    34801 attatcgctt gtttattagc tatttattac cgcaaatacg gttctagcag aaaattgctg
    34861 ccatggtttt tagggctttc tgtcgctttt cctttctttt ggttcattcg cgaagattct
    34921 atctggcttc ttccttttac tgtagtagct ttgggtatca gtttcgtcca gatcttgcta
    34981 gggcaagact tttctttcaa agaagtaaag aagttaaaaa aacgactctt tcttctctcg
    35041 aaacgggaat ggctgaaact ttcattgttt ttacttccta tagttggctt ttccatcgtc
    35101 tatcaatgga tcgaatataa aaatgagaca acatacggta ttgcaaccat caatgaccgt
    35161 tccagtggag aatttggacg tttgatgaaa caactgatcc gaatagatga tgaaacgaac
    35221 ttgaataaag aaaacagtga gatatgggtc tcacatgctg cactaaataa agcattagcc
    35281 gcatctccta cattccatac tgtttctacc cgtattgacg aattatatac gactcacgcg
    35341 tggactcaag gtggaaaagt aaaagaatta cccggagata tcatcttttg ggcattgcga
    35401 gatgtggtaa gcgaatctgg ttattaccaa aacaatgcaa aagaaaccaa tgatttttgg
    35461 aaaaaagtca accaagaatt agaagaagcc tatcacaagg gaacaatcaa aaagaaaaaa
    35521 gagttctatc tgatgggatc aggagatgga aagacgatga gtgatctgcc aatcgtattc
    35581 gatttccttc aatcaggata cgcttatgca tggcgatata aagatttcca tcaaggagga
    35641 aattatagtt tcggaacgca agaacaagtc aaacaggctc aagaattatt aaaccttccg
    35701 ctaatggaga attggatcga tagtaatgaa ccgagaacac ctaatttcca attaacaaaa
    35761 tcagcaaaag tcgcgaatgt catcataaaa atttaccaag ttctggctat tcccgtgctg
    35821 attgcttcaa tagcagggat attacttatg atactaggaa ccgtatttgc aaaagctgat
    35881 cgtgcctatt atagttcctc tttgattgtg gtcaccggat taatactgac acaattggtt
    35941 tttcttttcg gtgtctcatg gttttgttct tatgcgccag aaaaaaagga ctatttttta
    36001 agtgtctaca ctggtgcagg cgtgccatta acgcaattca tcgtagtaac aagcatgcta
    36061 gttttcagta aattaaatct gaaaaaagct ttatcttcta aataaaaaga cccttggtag
    36121 ctagattttt aacctaacta tcaagggtct ttgtgtggaa aaatcagttt ttattcgatt
    36181 tcttctaccg tttcctgcaa aagctgttca tattttttgt ttcctttata taaatcacca
    36241 atcgtccatg ccaacaggag aaggacaaga acaatgatta cataagcgat gtgatcagcc
    36301 aatgctagtt gagcggaagt ggcttgctcg ccgaagaaac tttcgatctg tcctggtaat
    36361 cctcgtaagt tcaagtaagt tagactaatc acagagaacc agccaagaag ttttacgatg
    36421 aatgaatttt taaatcggct acccatctcc gcttggctgt tggtcatcat cagtaaagga
    36481 atcatcgaaa acggcaacgc aaaagccaag aacacctggg attcattcat taagttattc
    36541 aaagcggcat gttcttcgat cgttcctttt gtacttgtaa acaaaacaca aatcaataca
    36601 ggaatcacag aaagcaatcg tgtgaccagt cttcttagcc aaatcgggat acgcatatgg
    36661 atgaatcctt ccatgatgac ttgaccggtc aacgtaccag taatagtaga gttctggcca
    36721 gaagcaagaa gtgctacagc aaataaagtg gacaagatac cagattttgc tacagcaatc
    36781 aaaataccat tgctcatagc tgatggatca gataaagctt catacagacc aaaaaaggaa
    36841 ggatcttgga cagaaccggt tttgaagaca gcgacaccca tgatcaatag cagtgcattg
    36901 actagaaaag ccattgacaa ctggatatta gaatcccaag tagaaaaacg tacagcttgt
    36961 gctacatctt cttcgttttg gtgatcgatc ttccgagttt gtgaaactgc tgaatgaaga
    37021 tataagttat gcggcatgac tgttgcacca ataatcccta aagctccagt cagcggagtt
    37081 tcgccgccga tgaccggtga gtctgagaat gtatgactgt tagggataaa gccagcaaat
    37141 aaactgtgcc aatctgggtt agacaagcca acttgataga caaaaacgaa taaaatgacg
    37201 aaaattaagc agacaaccag tgcttcgatc ttacgaaacc cgacttttgt cagtagtaag
    37261 agaacgaaaa catctaatac agtaataaag acggcaatca ccaatggaat atcaaaaagt
    37321 aagtagaggg cgattgctgc accaatgact tctgcaatat ctgttgccat aatggctaat
    37381 tcagtcaaga tccataaaat gacacctaat gtcttacttg tgcgtgctcg gattgcctgt
    37441 gccaaatcca tttggctcac gattcctaat tttgctgcca tatactgtaa aagcatagca
    37501 atcagactag acatcaaaat aactgacatc aataaatatt ggaaattttg tcctccggtg
    37561 atcgaagtag accagttacc cgggtccata tacccaactg ctactaacgc accaggtcca
    37621 gagtaagcaa gaagtgtttt aaaaaaactt ttcccctttg gtacatcaac tgttccattt
    37681 acttcagcta aagataaacc atttgtatgt tcaataagtc gatgcttatg aaattgttta
    37741 ttggattgat tattcaagaa aaaaccacct ttcctattta tctacgatta cattctacac
    37801 ctcaaaaaga aaaaattaaa gaaaaagatt cggtacgcct aatttttttt catggcgcgt
    37861 cttgctagat gacgaaagaa attttgttct cctctaaaaa aaccactatt ttttgcatga
    37921 aactaaagaa tacgcctttc ttttttcaat aaactttagt aaaataagtc attgagagca
    37981 attcggaaat agaaaggaga gatttatatg ttatcaacag gtattgtcgt acttattgct
    38041 attattgctt tgctaatcgg cgcagtaggt ggctttttcc tagcgcgtaa atatatgaaa
    38101 gactatttag aaaaaaatcc tcccgttaat gaggacatgt tgcgatcaat gatgatgtca
    38161 atggggcaaa aaccatctga gaagaaaatt cgccagatga tgcagcaaat gaagaaccaa
    38221 gggaaaaaat aggttctgac ccaacgactt tttacgggct gattttttca gtccgttttt
    38281 tatttcgtaa tttgttagac tattcagatt attcagcaaa aaagacaagc acagacaatc
    38341 ctaggctctt gataaagaca aaggaggagt aaaatgtcga tttttagaaa attaggctgg
    38401 ttttttcgtc aggaaaagaa acattattta attggggttt tctcgctatt cgcagtggcc
    38461 ttggtacagt tagttcctcc aaaagtgatt gggatcatca ttgatgagat cgccgataaa
    38521 aatttatcaa taaagatcat tttcgggtgg atcttcctat tgattatcgc tgctttttta
    38581 caatatcttt ttcgttatat ctggcggacg aatatttggg gaagtgcagc tcgattggag
    38641 aaagaacttc ggcagcagtt attcaaacat tttacagaaa tggacaatct cttttaccaa
    38701 aaatatcgga ctggggattt gatggctcac gcaacgaatg atttgaatgc gatccagaat
    38761 gtagcaggag ctggtatctt gacctttgca gattcagtga ttacgggcgg aacaacgatc
    38821 attgcgatga ttttgtttat tgattggcgc ttaacactga ttgcgctgat tcctctgcct
    38881 ttgctggccg tcacttcacg agtgctgggg tcaaaactcc atgatgcttt tcgtgattcg
    38941 caagaagctt tttctagtat caatgataag acacaagaaa gtatcactgg gatcaaagtc
    39001 attaaaacat ttggacaaga aaaagaagat ctagcggatt ttgaagaaaa gattgaagat
    39061 gcaattatta aaaacaaacg agtcaatttt ttagactcct tatttgatcc attcattacc
    39121 ttgattatcg gtctgtctta tgttgcaaca attattttag gtggaaagta tgtcttggaa
    39181 ggcacgatct cgatcgggca gatggtctca tttattagtt atatcggtat gcttgtttgg
    39241 ccgatgtttg cgattggtcg attgttcaac gtattggaaa gaggaaatgc ttcttatgat
    39301 cgcgtcaatg aacttttgca tgaaaagacg catatcgtgg aacaactggg tgcagtgcag
    39361 accccggcaa aaggcgagct gaatgtagct atttcctctt ttaattatcc gaaagaagaa
    39421 tcaccagcat tagaacaaat caagtttgcg atccaagaag gagaaacatt aggtattgtt
    39481 gggaaaactg gtgcgggaaa aacgacgatc atcaaattac tgatgcgtga atacgatgat
    39541 tatcaaggga aaatccaatt tggcggacgt tcgatcaaag aatattcatt gaatgcttta
    39601 ttaggatcaa tcggctatgt gcctcaggac cacttcttgt tttcgatgac cattcgagat
    39661 aatatccgtt tttctaatcc aaaactttca gaagaagaag tagagcatgc ggcttcttta
    39721 gcatttatca acaatgaaat caaggaatta ccaaaaggtt atgatacctt agttggagaa
    39781 cgtggagtct ctttatctgg cggacagaaa caaaggattt cgattgctcg agcattgatc
    39841 aaaaatcctg aattattaat gttagatgat gcactttctg cagtagatgc caaaacagaa
    39901 gaagctatct tgcataattt aaaagaaata agaaaagaga aaacaactat cattgcagct
    39961 caccgtttaa gtagcgtaat gcatgcaaaa gaaatcattg ttgtcgatca agggaaaatc
    40021 attgaacgag gaacccatca tgagctgctt gcactaggcg gctggtatga acaaatgtgg
    40081 gagaaacagc aattagaagc gaagatagaa ggaggcgagg cctgatggat gaaaattatc
    40141 aatcggaatg gacaaaatcg attccactta aagaacagaa aaagatcatc acacgactga
    40201 tgaagttcgc caaacctttt agaagaacgt tcatcgttgc tatcttattt gcgtttgctc
    40261 tgtctgtgat caatgtccta ttgccaagga tcatccaaac ttttatggat gatcatctgg
    40321 ctaaacagtc ggctacgaca caagttattt tgttttttgc tggtatgtac ttatttggag
    40381 tcatagtaaa aagtatcatt tggtttttcc aatggtattt gtattccatg gcttcattga
    40441 agacctatca gtatattagg gtaaaattat ttgaaaagct gcatacacta ggtatgcgtt
    40501 attttgatca gacaccggca ggttcaaccg tttctcgagt gacgagtgac acagaaacgc
    40561 tatttgaatt ttggtacgtc tttttgatgg tattgactgg gatctttgca gtcgtttctt
    40621 cattcattgc catgtttcaa atcaatggag aaattgcctt gtggactttg gtgttcttgc
    40681 caattttagg aatcgtcatc tggtattacc agaaatttag ttctcgtatt taccggaata
    40741 tgcgagaaaa attaagtcag ctgaatacga aattgaatga atcgatttcc ggcatgcgta
    40801 ttatccagca gtttcgccaa gaagctcgtt tagctaaaga atttgaacaa gtgaacaatg
    40861 agtatttaga cacgcgttat gcgatgatga aaacgaattc gattctatta agtccgatca
    40921 tcaattttct atatgcactg gcgattgcgt tggtgttgac tttgtttggg atcgatgcgt
    40981 tgcattctcc catagaagtt ggactgatct atgcatttac gacctatgtc cagggatttt
    41041 ttaatccaat gtctcaaatg atggactttt tgagcatctt cacagatggg atggttgctg
    41101 gtagtcgtat cttgaagatt atggatacag aagaatatgc accacaacaa aaccctggag
    41161 cagatcaaat gattacttca ggtaagattg agtttcgcaa tgtaagcttt tcttatgatg
    41221 gagagcacaa tgtattaaac aatatctctt ttgttgctaa tccgggagag accgttgcat
    41281 tagtgggaca caccggaagt gggaaaagct cgatcatcaa tgtgttgatg cggttttacg
    41341 aattttatga aggtcagata ttgattgatg atcatgacat tcgagaatat ccaatggaag
    41401 agttacgtaa gaaaatgggg ctggtcttgc aagatgcttt cttgttttat ggggatatcg
    41461 caggaaatat tcggatgatg aatccagcta tcacagacga acagatacgc catgcggctg
    41521 agtttgttca agcaaacaaa ttcatcgatg aattaccaaa aggatatcac tcaaaagtga
    41581 tcgaacatgg tgccagctat tctagtggac aacgacagct gatcactttt gcgcgaacaa
    41641 tcgtgactga tcctaaaatt ctagtattgg atgaagcaac agcaaatatc gatactgaaa
    41701 cagaaggatt gatccaagaa ggattggcga aaatgcgaca aggacggaca acgattgcga
    41761 ttgcccatcg gctgtcaacg attcgagatg cagaattgat tttagtttta gacaaaggtc
    41821 atatagtaga acacgggaat catgaaacac ttctagcgca aaatggtttg tatgcagata
    41881 tgtacaaact gcaaagcagt ggtatataaa agatgttgtg acagtagcat tttgacctaa
    41941 gcactagagt gaaaataaaa catagcttcc catatttttc atctgtgaga gttagtgtcg
    42001 tagttaccag atttaaaaaa gacgacgcca gctagtcaga agtgcctagt agcccctaag
    42061 aaagcgttga caaaatcgtt tgctttcgat aatacaaaga aaacgataca acttggatag
    42121 tgattgccta atgcaagcta aacctgatga gtctcccatg gtttcatgga cggctttttg
    42181 ggtttttctt tttgttttgg atacagccct atatatcatg gaaaggagca aaacatgctg
    42241 attgagaaag tactgaataa caacgtcgta ataaccaggg atgaaagaaa tcaggaaatg
    42301 atcgtgatgg gaaaaggttt ggcattcaaa aagaaagtgg gtgacccgat ttttgactca
    42361 tgcatcgaca aaaaatttca gttgacaaat gacggacttt cacaacagtt ccaagaattg
    42421 gcacaagcga ttcctcttga gtacttagaa atttcttgtg aaatcattga atatacaaaa
    42481 gaggatctac aagtccattt gaatgattct gtgtatattg cattgacgga tcatttgtat
    42541 acagctatcg aacgtcaaaa aatggggatc tttgtgccaa atgtattgct gtatgatatc
    42601 aaacaactgt ttcctaaaga gtatgccatt gggaaaaaaa cagtgaagaa aatctcggat
    42661 aaataccaca tcaagttatc agaagacaaa gccggattta tcgcattgca tttagttaat
    42721 gcacaaggca ttcaaagcca gcaagacaat acctacctgt ttaccacaac aatacaggat
    42781 attttaaata tcgtccgctg ttactataag attacttttg atgaagattc agtccatttt
    42841 tttcgatttg tcacacacct acgttttttt ctgacacgtg ttctagatgg agcgaaatca
    42901 gaagatggag aagtttctga ggaattgttc caagttattc aaaaaaaata taaggatacg
    42961 tttggttgcg ttgagaaaat agcagacttt ttaaccgggg ctttcgacta ccagatgtcc
    43021 acggatgaaa aaatgtattt aacgatccat actgcgcgtt tagtgcatga gaatcgttgt
    43081 aaataaataa aaaggaggac aaattaacac gaacgtatga aataagggta gtgacattca
    43141 gttggctaaa ccttccacta attaattgga gggaacagaa atgggaaaat accaagaatt
    43201 agcgagcaaa attgtagaaa atgtcggcgg gaaggaaaat atcaatggtt tgacacattg
    43261 tatcacaagg cttcgtttca aattaaaaaa cgaagaaaaa gcaaatgatg agatcttgaa
    43321 aaatatggac ggtattgtga cggtaatgcg agcgggagga cagtaccaag ttgtcatcgg
    43381 gaatcatgtg cgagtcgtgt ttgaagaggt tataaaagca ggaaacctta cttttgatga
    43441 ggctgtttca acagaaaaaa tgagaccgtt tgatatgctt attgatggaa tatcgggatg
    43501 tttccagcca ttccttgcta tcctggctgc tggtgggatg attcgtggac tgacagcatt
    43561 acttgtcttc ttaggcgcgt ttgatcgcgg ttctggaaca tttgttatgt tcgacaatat
    43621 cggtgattct gtattccaat ttatgcctgt tattatcggt ttaacagttg cccgtaaatt
    43681 taaagtaaat gaattcgtag ggatgttgct tggcgcagca ttaatgaatc ctaacttgtc
    43741 gctggaagtt ttgagtggtg cagcagaagc accactgacg accatatttt ctggtactat
    43801 ttttgaagca cctatttatc aaacagtatt tggcattccc tggattgcgc gtaactacgc
    43861 ttcttctgtc attcccatta tctttattgt gttgttagct agccaaattc agaagccaat
    43921 taaaaagtta gtacctgaga tgatcgcgaa tttcttcgtt ccattcttca ccgttcttat
    43981 tacaatgccc ttaggttttt tactcgttgg accagcattc acattcgcaa ctgatatttt
    44041 aatggctgga tttgaaacac ttttagcact ttcgccagtt aattatggag caatcgtagg
    44101 cttcttctgg caaattctgg tgatgtttgg tctccattgg gcaatcgtac caatgggatt
    44161 gatgcaattt tctgtgaatg gctggcaaaa tatcatgaca cctgttgcag tagtgtcttt
    44221 tggacaaact gcagcactta ctgcactcta ctttaagctt agaaacccaa aagacaaagc
    44281 aatcgcaatg ccagccattg tttctggtat tgtggggatt acagagccag ctatttatgg
    44341 gtttacattg ccacgtaaaa aaatatttat ttttacctgt gtcggtggtg cgttaggggg
    44401 cgcgtatagt gggttaatga atttaacttc ttggaatcaa ggtggactag gcatctttac
    44461 gattcccaac tatattagac cagatggtga tttaacagat gtgattaatg tattaattgg
    44521 gatcgccatt gcgatggtgg tatcctttgc gctgactttt ttcttttgga aggatgaagc
    44581 aggtgaaaca gatgatatac agaaaagatc gggtaaagaa attgtaaaaa caccgataca
    44641 aggacaaatc gctccactaa atgcagcgaa ggatgcagct tttgctcaag gaacattagg
    44701 tcgagggatc ctgatctacc ctgaaaaagg agaagtacgt gccccttttg acggaacagt
    44761 tatgaccctg ttcccgacga aacatgcaat cggaatggtt tctgaaacag ggctggaatt
    44821 gctgattcat gtcggattgg atactgtgca gttggaaggg aaatattttg aaagcttagt
    44881 gcagcaagga gaaagagtga aacaaggcga cctgttgcta cgcttcgaca aaaagaaaat
    44941 cgaaaaggaa ggatacagtt tagaaacacc tgtgatcgtc accaattata cggattattt
    45001 ggatattttg gaaaaccaag gggagacggt cgggccagac gatgcactta tcaccgcact
    45061 gacctgaacg gttaggtgaa gaatggacta ggcttaacta ttctttttat tccacttctt
    45121 tattttcaaa attgaaaggc tctttcatga tggctgagct gatagggcgt ttatcgaatt
    45181 tttgaccgac agaaattaga tggactaaat tctgctgata attttctgca aaaacacaac
    45241 tatataacac gtctagaaga taacaaattg atgtattgat cgtaaaatta ccaatttttg
    45301 aatacagtcg ctcgcgtgtc gtaagtcgca aagcggctgt actcattgca gatagcgttg
    45361 aatcaccgat actggtcaaa gctaaaattg gaacatcatt ttgtttcaat atttctgcgg
    45421 tacgaaggat cacattgttt tcacctgtat aagaaatcag aatcccgcac atatcgctcg
    45481 tgcaattgta cgcttcatag aatgattcac caaaagtggt gacaattgtg acatccattt
    45541 tgatgcgctt cattttcagc atgaaatctt gagaaatcaa agtattcgag ttactggcga
    45601 agatcacgat tttttttgcc tggagcagta aatacttagc tttttgcagt tggtcatgat
    45661 gaatgagaga aagtgtatct tgaatcgtca tctgttctaa agaagccatt ttatttgcga
    45721 tcgtcataat accgtctgtg gtggaaaaag gaagattcgc atctacgtct tgaaaattcc
    45781 cttcaagata ggctgtttca gctaaaaaag cattacgaaa actgacccag ccatcaaacc
    45841 ccattttttt tgctacacgg atgagtgtgg acgggtggac ataacatcgc tcagcgatct
    45901 cttggatggt catttcgcca agtgctggag aatcgcttaa gagaaactgg atcacttcat
    45961 tttctgaagg agaaaaggag atttctttga ttttttcacg taataacatg tagatacctt
    46021 cttcttattt ttttacgtaa attataactt ttttgaaaat gatttgtaaa cggatttata
    46081 ctatataact taaaatagac attttttgac aagatattta caaaaatcca ctagaaaaca
    46141 gtaacttttg taaatgttac tggaaagaaa cggatttcta ttgtttgttt tgtttacaaa
    46201 aaagataatt aaagtgtaaa aaagtaaagg agtgagaaca tggcaaaagg aatcaaaatc
    46261 gctacgattg gtggaggcag cagttacacc cccgagttga tggaaggatt tatcaaaaga
    46321 tatgaggaat taccgatacg agaaatctgg ctcgtagatg tagaagaagg aaaagaaaag
    46381 cttgatatcg ttagtcagat gtctcagcgt atgtgggatg cttctccgta tgaagtcaag
    46441 atctatgcaa ctctggatcg ggaagaagca ttgaaagatg cggattttgt tacgactcag
    46501 tttcgtgtcg gtcaattaga tgcacgaatc aaagacgagc ggatccctag ttattacggg
    46561 atgatcggac aagaaacaaa tggtgctggc gggatattca aagcttttcg taccgtgcca
    46621 gtggtcttgg caatcgttga agacatgaag cgtttatgtc caaatgcttg gctgatcaat
    46681 ttcgcgaacc caagtgggat ggtgacagaa gcagttatca gatatggtaa atgggataaa
    46741 gtgattggat tatgcaatgt gccagtaatg gcgatgatga cagaaccagc aatgcttggc
    46801 aagaaaaaag aagagctgat ctacaagttt gccggtctaa atcatttcca ttggcacaaa
    46861 gtagcagata ataaaggaaa tgaccgcacg gcagaattga ttgatcgttt atacgatgaa
    46921 gacaatggat tgccgaaaaa tatctttgat atcccgtttt tcaaagaaca attaaaacaa
    46981 atgaacatga tcccttgtgg ctaccaccgc tattactatc gtgaagaaga aatgctggaa
    47041 catgctttag aagaatatca aacgattggt acaagagcgc agcaagtgaa agaaacagaa
    47101 gcagagctgt ttgaattata caaagatcca gaattagacc ataaacctga acaattgcaa
    47161 aaacgaggtg gcgcttatta ttcagacgct gcctgtgaaa cgattacttc aatctatgga
    47221 aataaagaaa cacagatcgt tgtatctaca aagaatgatg gagctgttcc tgacctgtcg
    47281 gcagattgtg ttgtagaagt cactgcctat gttggcgcac aaggagcgag aaatgtagcg
    47341 tttggttctc ttcctgctgc tgaaagaggc tggttgcagg taatgaagaa tatggaattg
    47401 ctgacgatcg aagcagctgt gactggtgat tatgggacag ccttacaggc gtttacgatc
    47461 aatccactta tacgatcagg aaagacagca aaacggatca tggatgagtt gtttattgca
    47521 caccagcagt atttaccgca attcaaggaa acaatcggcc gattaaaaga agaaggaatc
    47581 gaagttcaag atgaactggc aagagaatta tcaagtaata cacatataat ggaggaagta
    47641 taatgggatt cagaaaagat tttttatggg gcggtgctac agcagccaat caatgtgagg
    47701 gcggttatga tgaaggtgga cgcggactag caaacgtaga tgttgtgcca atcggaaaag
    47761 accgttttcc tgttatcacc ggaaagaaaa aaatgtttga atttgatgag gaccattttt
    47821 atccagcaaa aattgcaatc gatatgtatc atcgttataa agaagatatt gctttgtttg
    47881 cagaaatggg gttcaagact tatcgaatgt ccatcgcctg gagtcgtatt tttccaatgg
    47941 gggatgagaa agagccgaat gaagctggct tgaaatttta tgaggatgtc tttaaagaat
    48001 gccaaaagca cggaattgag ccacttgtga cgattacgca ttttgattgt ccaatgcatt
    48061 tgatcaaaga atatggtgcg tggcgttcca gagaactcgt tggtttttat gaaaatctgt
    48121 gtcgagtcat cttcaatcgc tataaaggac ttgtcaaata ttggctgaca ttcaatgaga
    48181 tcaatatgat ccttcatgca ccattcatgg gcgcagggct gtattttgaa aaaggagaaa
    48241 atgaagaaca aatcaaatat caagcggcac atcatgagtt ggttgcaagt gccatcgcaa
    48301 cgaagattgc tcatgaagta gatccggaga acaaagtagg ctgtatgctg gcagcaggag
    48361 catattatcc atacacttgc aatcctgaag atgtttggga ttctagaaaa tcagatcgag
    48421 aaaattattt cttcattgat gttcagtcac gaggagaata cccagcttat gcattgaaag
    48481 aaatggaacg aaatggcatt cagatcgaaa tggaaccagg ggatgccgca ttgctgaaag
    48541 aacatactgt tgattttatc tccttttctt attattcttc ccgagtttcg actaccgaca
    48601 acgaactctt ggaacagact gcaggaaata tctttgcttc tgtcaaaaat ccatatctgc
    48661 aagcaagtga atgggggtgg caaattgatc cattaggctt gagaataacg atgaatgata
    48721 tttatgatcg ttatcaaaaa ccattattta ttgtagaaaa cggcttaggt gcagtcgata
    48781 cgccagatga aaatggttat gtggaagatg attaccgaat cgattacctg gcagcgcata
    48841 tccaggcgat gaaggatgca gtagaactag acggagtcga tctattaggc tatacgactt
    48901 ggggatgtat tgatttagta tcagctggta ccggtgagat gaagaaaagg tacggattca
    48961 tttatgtcga tcgtgataac caaggaaatg gcacattagc ccgttcaaag aaaaaatcat
    49021 tcaactggta taaaaaagta attgattcaa atggagaaaa tctttcgaac gattgatcaa
    49081 tgatttataa aagtctattg tttttcagcg gatttttcga gtataataaa gctattcgag
    49141 aaacgcaagc agaacaatag actttttttc gcattggctg taaagtatgc ttacttgatt
    49201 aagtaaagga gaatctacat atgtatgatg taatcgttat tggcgcaggt cctgctggga
    49261 tgactgctgc tttatatgct tcacgttcaa acttatccgt attgatgatc gaacaaggtg
    49321 cccctggcgg ccaaatgaac aatacggcag aaatcgaaaa ttatcctgga ttcgattcga
    49381 tcatgggccc cgatctagct tataagatgt atgaaagtgt ctcaagattt gggacagaaa
    49441 atgcttatgg aatcgttcaa gatatcaagg atcacggcag ccataaagaa gtcatctgtg
    49501 aagataaaag ttacgaagga aaaacagtca ttatcgcaac aggctgtatc caccgtaaat
    49561 taggcgtacc tggcgaggaa gaatttgctg gacgaggcgt ttcttactgt gcagtctgcg
    49621 atggtgcgtt tttccgtaac aaacgtctag tagtcatcgg gggtggggac tcagcagtag
    49681 aagaagccat ctatttgaca caatttgctt ctgaagtagt gatcgtccac cgtagagatg
    49741 aattacgtgc acaaaagatc atccaagacc gtgcatttgc aaatgaaaaa atttccttta
    49801 tgtgggatac agtcgttgac gaaatcgttg gaaacgaaat ggtagtgaca ggtgtgaaag
    49861 cacgtaatgt caaaaccggc aatgaatttg atttagcagc agacggagta ttcatctatg
    49921 ttggactgga tccattaact gcacctttta gagaagcagg tttgacgaac gaagctggct
    49981 ggattccaac agacaacgaa atgaaaacga atatgccagg cgtttttgcc atcggagatg
    50041 ttcgtgaaaa agatttgcga caaatcacta cagctgttgg tgacggcggt attgctggac
    50101 aacaagtgta taaatacttg gagtctttag aagaaacaac agcataagtt taaaaagagt
    50161 gaaagaacgg ttttaattgt tcttttactc tttttttttc gcgtgaaatc cactgaatcc
    50221 gatttatgtg aatacttgca atcatgcttg ataaaagaat cctttcttga tttaagcgtt
    50281 ttttggtcct catactttca tatctaataa gtgaatgcta tacttattaa gaaccatatt
    50341 tcagaaagag gtgttatttt catgtcttgg gaacaagtgt atgaacaatg ggtacatgaa
    50401 gaaaatttag aagaaaactt aaaaaaacaa ttaaatgatc tgggtgaaga tcctgaaaaa
    50461 cttgaagatg ctttttatgc accgttggaa ttcggtactg caggcatgcg gggaatctta
    50521 ggacctggga tcaatcgaat gaacatctat acggtaagac aagcaacaga aggactagca
    50581 cgtttcatgg atacacaagg tgaagaaaca aaacgccgag gtgtcgctat cgcttatgac
    50641 tcacgccatc agtcaccaga atttgcaatg gaagcagcca aaacactggc acatcacaat
    50701 atcccgtctt atgtattcga aagtctgcgt ccaacaccag agctttcttt tgcagttcgt
    50761 catttgaaga cgtttgcggg aatcatggta accgcatctc acaacccagc ggcttacaat
    50821 ggatataaag tctacggaga agatggcgga caaatgcctc ctgcagacgc agatgcattg
    50881 acgaaatatg tccgtgaagt cagcaatccg ctaaaagtcg aagtattatc tgacgaagaa
    50941 gctaaacata gcgggttgat cacgatcatc ggagaagaag tggacgctgc ttatctagaa
    51001 gaaatcaaag cagtgacgat tgatcgtgaa ttggttgaaa caatggggaa agatttgaaa
    51061 cttgtgtaca cgccacttca tggaacaggg aaaatgttgg gcgaacgcgc gttgaaacaa
    51121 gctggattcg aacaattcgt actagttccc gaacaagctg tggcagatcc agatttcact
    51181 acggtcaaat cgccaaatcc agaagaacat tcagcttttg aatatgctat acgacttgga
    51241 gaaaaagaag gagctgactt gctgattgca acagatcctg atgcagaccg tttaggcgca
    51301 gcggttcgtt tgccagatgg ttcttatgaa gtattgactg ggaaccaaat cggagcattg
    51361 tttgctcaat atattttgga agcacatcaa tcaagaggca ctttaccaga aaacgcagcg
    51421 gtattgaaat caatcgtttc cagcgaattg cctacagcaa ttgcggaaca ctacggtgct
    51481 accatgttca atgtgttgac agggtttaaa ttcattgctg aaaaaatcca acaattcgaa
    51541 gaaaaccatt cacatacttt tatgtttgga ttcgaagaaa gttatggtta tttagttaaa
    51601 ccttttgttc gcgataaaga cgcgatccaa gcattgcttt tattagcaga agtagcagct
    51661 tactataaaa aacaaggcaa aacgttgtat gacggcttgc aaacgatttt tgaaacctat
    51721 ggctatttcg cagaaaaaac gatttctgtg acaatgagcg gacaagaagg ttctgcgaaa
    51781 atctctgctt tgatggaaaa attccgtaaa gaagcaccga cagaatttgc cggagcaaaa
    51841 gttattcaaa cagaagactt taaagaattg acgagaacag accgtgaagg aaacgtagaa
    51901 aaactcacaa caccgccatc cgacgtattg aaatatacat tggaagaaaa tggctggatt
    51961 gctatccgcc cttcaggaac tgagccgaaa atcaagtttt atattggtgt aaaaggaagc
    52021 tctacagaag acgcagccaa aaaagtagcc tcttatgaag cgattatcaa aaagatgaca
    52081 gaagaataaa aaacttgaga ctgatggaaa aagtggtaaa ctttagaagt cagtcttttt
    52141 tcaagttgga ggtgaatgga ttgccagaca cgcaaaaatc aaaagtagag aaagtcagtc
    52201 aattattcaa aatgttgagt gatcccactc gtcttaaaat tctgctatat ctgaaagacg
    52261 gggaacaaaa tgtgacagca atcacccaag cagtggaaat ggagcagtct gctgtatcgc
    52321 atcaactacg tttattaaga gaaaatcatg tcgtcaagtc tcatcgcgag ggaaaagcga
    52381 ttttgtatag tcttgatgat tctcatgtac tggatatttt gaaccagaca ctcaaacatg
    52441 tggaacatca ataacgatag gtgcaaatag ataaacactg gagtgtgaca acgaaatttc
    52501 ttcgttgtca cactccagtg ttttttaaga aaaagacaaa aatgatcaat cgcttttttc
    52561 tgttgtttca gttccataat aactatgatc ttctaggtct aaagcattca aaataagcga
    52621 agccgtttct tcaatagata aagatgctac attgatcact acacatccta gtttttcata
    52681 aagatcattc gcaaaatcga gttcagctct aattttttcg atatcggaat aagcagtatc
    52741 agggtttaat ccgtaagagc gcatccgttc tttacggata ttatttaaaa tatctgggtt
    52801 attcgttagt cccacgattt ttttaggatc gatctcccaa agctgtttgg gaatatgtgc
    52861 ttgtgggatc aaaggtaaat tggcaacttt taaatttttg ttagctaaaa acaagctcaa
    52921 aggcgttttg gaagttcggg atacgcctag caaaacgaca tctgcttcta aaaaaccacg
    52981 aggatctttc ccatcatcgt attttacagc aaattccatt gctttgatcc gtttgaaata
    53041 gttctcattc aataaatgga gggcaccagg ttgccgaatt ggcttgatac cagttaaacg
    53101 ttcaatttct gatatcggtg gcgtcatcac atcaaaacta aataattgat gttcttcaca
    53161 aaaagaacgt gttatctcga tcagttcttg attgattaat gtatgcagga caagtgcttt
    53221 ttcttctaat gcatcttgca atgcctgcct taatgttttt tcatctgtca cgaacgttct
    53281 gcggaatagg ttgaactcaa cggtaggata ctgagccata gtagcttgcg ctagttttgt
    53341 cgcagtttct ccagcagagt cggagatgac aaaaaaagta acgatttctg tagaatcgga
    53401 agtcatggat aaaacctcac ttgcattttt tttatgttta ttataccata ctctagaatg
    53461 cgtacttcgt aatcattttg atttggagga ataagtcatg aaaaaacaga cattgatcga
    53521 acaatcatta gaaacattga aaaataacgg ttttaaatat actaaaaaaa gagaagcatt
    53581 gttaacttat ttagtgaagc gtaaccgcta cgtatctgct aaagaagttt ttgactatat
    53641 gaatcaggaa ttcaaagggg taagttatga tacgatttac cggaatctcc atgattttgc
    53701 agagatcgat ttactggaag aaaccgattt aaatggagaa atgaagtttc gttttcattg
    53761 ctgtcagggg gaaatcggcc atcaccatca ttttatctgt acagtgtgcg gaacaacgaa
    53821 agaaatccat atgtgtccga tgaattattt cgaagaacag ctaggtggat gcacgatcga
    53881 agggcataga ttcgagattt tcggaagatg tgaaaattgt caataaggat ttaaataaaa
    53941 taacatttga taatttaaaa aaaaagcaag atttccttga cggtcaaaac agcattagat
    54001 ataatattta caggacagtc ttgttttttg agatatattt caataacaat tacggttact
    54061 ttttaagctc ggagggaggg aattaacatg tcaaaaacag tcgttcgcaa aaacgaatca
    54121 cttgacgatg ctcttcgtcg cttcaaacgt tccgtgtcaa aagcgggtac tttacaagaa
    54181 tctcgtaaac gtgaattcta cgaaaaacca agtgtaagac gcaagaaaaa atctgaagca
    54241 gctagaaaac gcaaaaaatt ctagttctgt gatgaattgg agttggtagt gtgtcactac
    54301 taagtagatt aaacgatgac atgaaagcag cgatgaaagc gaaagataag gaatctttac
    54361 aagtcatccg aatgatcaag tcatctatac aaaacgagca gattaaagaa ggtcacgact
    54421 tgacagaaga agaagaacta acggtgttgt ctcgtgaaat gaaacagcga cgtgattctt
    54481 tgcatgagtt tgaagaagca ggacgtgacg atttagctga aaaagtaaaa agtgaaattg
    54541 taatagtcga aaaatatatg ccggaacaac tttccgacga agaaattcga caacttgttc
    54601 aagaagcaat cactcaaact ggtgcttcat caatgaaaga atttggcaaa gttatgggtg
    54661 caattatgcc taaagtcaaa ggaaaagcag atggaaacca agtgaatgcg attgtgaaag
    54721 aactattaca atcttaattt tatcatttaa actgcggaca gtgattatcc gcagtttttt
    54781 gtgttcgtaa aaaaagaact aaaaaacagc tagaagaaag aatcttattc tttcttctag
    54841 ctgttttttt cctgtttaat atctcttatg ttaaattgtg tttgatttgg ttattcttct
    54901 ggtaactcac ttgcttcttg tttatatcct gatacgcgat atacataata aaagagcaag
    54961 ctgccagcgt aaccaagcaa cgttgggacg acccagccaa gacctaatgc agcaaaagga
    55021 acataatgat gataaaatcc tagtaagctt gctacgacag tttgctgact cactaatgca
    55081 ggcgaatttg ccaacatatc caatacggct ggaacggcag aaaagaacat cgttacttga
    55141 tagacaaatg gactcttttg gaagaatttt gctgttaagg aaagtaagat taacgcaagt
    55201 gacaatggat acaaaagcat caatactggt aaagaccatt ggatgatatt atccaatccg
    55261 gcattcgcaa cgacaaaaga gacaaaagtc gttaaccgca gccatgtcat ataactgact
    55321 ttagggaaca gtttatggaa atcttgtgca aaagaaacaa cgagtcccat agcagtagtg
    55381 aagacaccta atgtgaccat tacccctaag aagctagcac cgaagttacc taaataaaaa
    55441 ttagtgatct gagaaagtgc agttccgcca ttttctgata aagacatctt attcaaactc
    55501 atcgcaccga gaaggaccag accaaaataa atcatgactt ctaacgcaac gctcaggcta
    55561 ccagcttttg ctgttaattc tgtgactttt ttatctttaa aaccaagatc acgaactgca
    55621 tggacaaaag tgacacttaa agcaagtaaa gctactgcat caaccgtgtt gtatccttct
    55681 aaaacgccat ttgtcaaagc gttcgtctga taagaatctg cagcagattg gtttagattc
    55741 cccatgggtt ggaataaaga aacgacaaaa atgatagcta ataatgcaag aaacaaggag
    55801 tttaaatact ttccgacata tttgaccaaa cgtgttggat gtacagtaag gaaataagca
    55861 agtaaaaaga aaagagcaga gaataaaaac atacctaatg aatcatattt ttcaggcaaa
    55921 aagggtttag cagccatttc aaaagcagtt gctgctgtcc gcggtgtacc aaagaatggt
    55981 ccgatcgtta aatgaacaag gatcaagaac aaggcagcat accattttcc gacaggttta
    56041 gctaagtcat acagaccatc actttttgtc actactacag ctaagatagc taataatggg
    56101 aaaagagcgc ctgagatggc aaatcctaca ccagcgctga tccagtttga tccagccatt
    56161 tgacctaagt gtacaggaaa gatcagatta cctgacccga agaacatccc gaagataagt
    56221 gaactgacca tcaataattg cttccatgaa taagtttttg tttcttccat aaatttttcc
    56281 tccaataatt atcattttga gtaacaaaat aaacgttgca gaaactagaa ataccactaa
    56341 tatcagattc catgaaaacc accaccttaa aatataaaaa aagccctttt ccacttggga
    56401 aaagggctct agattctaga acggtaccac cttttttcgc ttaaaaaagc ttcttcattc
    56461 acggacgctt ttcgataaag ttatccgcta gcctgataat ggaggcagcc acaatgatct
    56521 acgttttcga cattgactcg gaaatgatgt tcgtctattc gatttattgt catttctcac
    56581 ttacatgact cactgggaat aaatcactga atagcctact gttttcctcg acgctttgct
    56641 gtatatttat ttgttgacgt tataatacac ctgttttttt tgaaatgcaa gaatatttca
    56701 aatattttgt tttctttttt tgaaacaaga aaaataccca gagaatactt gctaagttag
    56761 acggaatact tgtcctctat cttatgcata gcttacatga tcagcttttt ttattcaaac
    56821 gagaccttta gagaatggaa gcggctagtt ttttaacgtt tcttggtact tatggttaag
    56881 caactctttt agaacctttt cttatttgct atatagtttc ttctgagtat ggtaaaatag
    56941 gaaagaatta atcgaaaaaa aggggatgtc tatttttgac ggaagagtct agttctttag
    57001 agattagatt gacggctgct gatgatgtca gcatgctttt aggtgcacac gacaagcata
    57061 taaaactgat tgaggaaaca acggaaacaa ccatccatac acgtggagaa atcattcaga
    57121 tcattggtga gcaatcccag atttccttgg ctgcctcagt cattcggaca ttacaggaat
    57181 tgatcaaacg aggaatccac gtaagtacgc ccgatgttgt gacggcattg aaaatggggc
    57241 aaaaaggtac attagattat tttgttgaga tgtatgagga agagatcgtc aaagaccgta
    57301 atggaaaacc tatacgggta aaaaacagcg gccaaaagaa atatgtcgaa tcggtagcca
    57361 aacatgatat cgtatttggc gtaggaccag ccgggacagg aaaaactttt cttgcagtag
    57421 tattagcaat cgctgccttg aaaaaaggtg aagtgcaaaa aatcattttg acgcggcctg
    57481 ctgtggaagc aggtgaaaat ctaggctttc ttcccgggga tctaaaagaa aaagtggatc
    57541 cttatctgcg gcctgtttat gatgctttat accaaatttt tggattggat catacgaacc
    57601 gattgatgga acgaggcgta atcgaaatcg cacctttagc ttacatgcgg gggcgaacat
    57661 tggatgatgc attcgttatc ttggacgaag cacaaaacac gacagtcgct cagatgaaaa
    57721 tgttcttgac ccgtctcggt tatcaatcaa aaatgattgt caatggggat acaagtcaga
    57781 tagacttgcc tcgagggacg acaagtggtc ttgttcatgc agaacgaaca ttaaagcaaa
    57841 tcaagaaaat cgattttgtt aattttgaag caagtgacgt tgttcggcac cctgtagttg
    57901 ccgaaatcat caaagcttat gaaaaggcag atctccatca agaataagct ttgcttagga
    57961 ggataagcac atgttgaata aaacactgca gaaactacaa gaaaaacttg gaaaggcagc
    58021 attgcctttc ctgctgttct tgttttttat cattatctgc ggcgttacat ttagtagtgt
    58081 caaacaaaag gtcaatgatt tcagagaagg ccaagtagca gaagaaagta tccgtgcgaa
    58141 caaaacgatc gagaacacgg aagaaaccga acaaaaaaga aaactggcag cagaagcagt
    58201 cactccagaa tacacttacc aaaaagatct tgcagatgac cagaacaatc ggatcaagca
    58261 actatttgaa ttgatcgata agacgaatga tgccatcaac aaatcttatg acgaaaagat
    58321 tgataaggca aaggaagatg aaaatatccc aaagcctact acagaagagc ggatcgccgc
    58381 gctgaagaaa aattttgaaa atgtgaatgc agaaaatgtt gtgttttatc aaaaactacc
    58441 gaacaatttt tattcgacga tatttgaaat gactgaaact gagattcata ctgtgaggga
    58501 tgagagtctg aagctcattg acgaacagat gagcaaacaa gttcgtgaaa gtgaattgga
    58561 agcttttaaa caagaagcag aagagcaaat ccaatatttg aatgtcacac cagcacaaca
    58621 acaaatgatt cgctacttag tggatcaagg tatcgtagtg aatgacgtat tgaatgagaa
    58681 aaagacagaa gaattgaaac aatccgcacg agaagctgta cagccagtga tgatcttcca
    58741 aggagaaatc attgttcgtg aaggtaatca aatcgatgct tcagctatga aaaaattgga
    58801 attactagga ctgactaatc aaacaacttc gatttttccg ctaattgcca tggttttagc
    58861 tgttttgctt caaatcggcg tactgattta taattcactt caattccaaa atgcaggaga
    58921 aagaacaaaa tacgtgcttt tctatgtgac agctatgtca gtcagcatag tgctgatgaa
    58981 atttttccaa ttattccaaa cggaacaagc tacttatatc ccgctgtttt atcccgctgc
    59041 ttttgcacca cttgttttaa gctttttctt gaatcgaaga gcagggatca tggctggtat
    59101 tttccaagca gtatccgcac ttttcatttt ttatgattcg attggcacga actttctaac
    59161 gattatcttg atgtcttatg ttttctctgg gctcatggca acgattgtca gacgcaaacg
    59221 gatctcagaa caaggattat ctgctgccat gtgggtcatt atttttcctg tgatgatgga
    59281 tgtcattttg atcgtctatc aaggaatgag ctttggtgat gcaacgactt ggttaatgct
    59341 cgtctgcggg ttcactggtg cactcttctc attcttgctg acgatcggtc tacacccata
    59401 tattgaattg atggtcaatg atgacagtgt aattgtatta aatgaactca gcaatccaaa
    59461 tcatccttta ttgaaacagt tgctggaaga agcgccaggt acttatcatc atagtatgat
    59521 ggtagctaat ctaagtgcta acgctgtagc agaaatcggc ggacgttctt tgctaactcg
    59581 agtagcttgc tattatcatg atatcggcaa gatcaaacat gctagctttt tcgttgaaaa
    59641 cttgccttca ggagcggaaa acccgcacaa tttcttattg ccagaagaca gtaaacatat
    59701 tatctttgga catgtgacag atggagccaa aatattggaa gattataata tgccgcaaat
    59761 ggtgatcgat atttgcaaac agcatcatgg aaccacgcta atgcgttatt tctacatcaa
    59821 agcgaaagaa cgcaatccgg aagtaacaga agagcaattc cgttatcctg gaccaaaacc
    59881 gcaaagtcgt gaagcaggga tcgtcaatat tgctgacagt tgtgaagctg cagtacgggc
    59941 aatggatcat ccgacgagcg aaaaaatcga aagttttgtc cataatctta tcgaagagcg
    60001 tatttccgat ggtcaattag acgatagtgg actgaccttg aaagaaatcc gaaaagtgga
    60061 aaaatcatta atcagcggtt taagtagcac cttccattct cggatcaaat atcctaaaat
    60121 gaaaacagaa gttgagaaga taaaggaaga acaagaagaa tagaaagaag cgatgtataa
    60181 tggatattac ctttatggat gaaacaaacc aagtctcaga agagaaaatg aaagaaatcg
    60241 atgacttgct gcaatttgca gcatcttatt taaagctgcc agaggaaaca gaaatgtctg
    60301 ttactttcat ggacaatgcg gcaatccaag taatcaatcg tgattaccgt ggaaaagatg
    60361 caccgacaga cgtcatcagt tttgctctgg aagaagaagg cgaagacgaa atcccagtga
    60421 tttttgaaga tggagagaat ccattacctc gtgtactagg agacatcatg atctctattg
    60481 aacgtgctgc tgaacaagca gaagcttacg gccattcata tgatcgggaa cttggctttt
    60541 tagcggtaca tggattcttg catatcaacg ggtatgacca tatgacacca gaagatgaga
    60601 aagaaatgtt tggtttacag aaagagatct tggatgccta tggactcaaa agataaaaac
    60661 gtagagaaaa acaaacattt cctgatgtct gtggaatttg ctgtccaagg agtcaaaacc
    60721 gtttttgagg aagaacgcaa tatgaggaaa catgttgcgt tcggtattct tgctttattt
    60781 atgggcgtga ttttccagct tgatcggata gagtggttat ggctgctttt agctgttttt
    60841 ctcgtttgga tagtagagat catcaatact gtttttgaaa atgtagtgga catgtttacg
    60901 gattttcatt ttcatccgat tgggaaaaaa atcaaagata tggcagctgg agcagtttta
    60961 gtgaccgctt gttttgctgt catcattggg ttgattttat ttgtccctaa aatatatcat
    61021 ttgttgttta attaaaaagg agaacgtata tgccagaaca taaatcaggg tttgtcgcaa
    61081 tcgtcggccg cccgaatgta ggaaaatcca cattattgaa ccgaatcgtg ggtcaaaaaa
    61141 ttgccattat gagtgacaag gcacagacaa ctagaaataa aatccaagga gtatatacta
    61201 caccagaagc tcagctgatt tttatcgata caccaggaat ccataaacca aagcatcgtc
    61261 taggagattt tatggtagaa gcagcttaca gtgcgttgaa agaagtggat gcagtcttat
    61321 ttatgatcag tgctgatcaa aaacgcggcc ggggagacga ttttattatt gaacgtctaa
    61381 aaaacgtgca ttctcctgtt tatctgatta tcaataaaat cgataagatc catccagacg
    61441 agttgctggg aatcatcgaa gattattcga cgcagatgcc ttttgcacaa gtgattccga
    61501 tctctgctac agaaggaaac aatgtcgaac gcttaatgga tgtattagtc agtgaaatgc
    61561 cagagggccc acaatatttt ccagatgatc aagtgactga tcatcctgaa tacttcatcg
    61621 tttctgaatt gatccgtgag aaagtcttgt ttttaacacg agacgaagtg cctcattctg
    61681 tcgcagtcgt tgttgattcg atgaagcgaa acgagaatga taaaatccat atccaggcca
    61741 cgatcatcgt cgaaagagat agccaaaaag gaatcattat cggcaaaggc ggaaaaatgc
    61801 tgaagcaagt aggaacgaaa gcaagaaagg atatcgaaaa tcttttagga gacaaagtat
    61861 ttctagaact ttgggtcaaa gtccaaaaag actggcgaga caaaaaagtc tatctgcaag
    61921 acttcggcta ccgaaaagat gaatactgat attctgaact tcttataggt taagtataga
    61981 aataaactgg ataaaaatcc gcacgttgag aaaaacggcg gaagatcgaa acataaataa
    62041 tctggatcgg cagaatctgc ttttccagat ttatttttta ggagggagaa tatgagccag
    62101 cttgcagaat cgaaaggctt gattttatct agccgtaatt acaaagaaaa agataaatta
    62161 gtcaaaatct ttacggaatc ttctggcaaa atgatgtttt atatcaaagg aatccatcgg
    62221 caaaatcagc cattagctcc ggctttgctc ccctttaccg aagcagtcta tatcggtaat
    62281 tttcgaagtg aaggtttgtc gtttttaagc agtgtcaaag acgtccatgc gtttcggaac
    62341 atccaagaag atatcttttt gagcggttat ggtacctatt tgctaaatct agtagatgca
    62401 gcaatcgaag atcatcaata tgacccgcat ttattccaat ttacgcaaca agctctgcag
    62461 cggatggatc aaggagatga tgcagaaatc atcacgaata tctttgaagt tcaaatactg
    62521 caacgcttcg gaatcgcgcc aatttggact cactgtgtcg tatgcggaga aacaaaagga
    62581 aaatttgact attcttccaa atatggcggt gtgatatgcg agaaacactg gccaatggac
    62641 gaacaccgtt atcatgcaga tcctcgtgct gtttatttcg tccgaatgtt ttcggctatt
    62701 tcttatgata agatcagtgg aatccacttg aaagaagaaa cgaagcaggc aatccgtgac
    62761 ctcattgacc agttgtatga tgaatatgtc ggtattcatc taaaaagcaa aaagttcatt
    62821 gatcaaatga agtcttgggc acacgtatta aagacgccag agaaaaatat gcctgaaaaa
    62881 gagatacctg aaaaagaaga ataaatgaaa gatacaacaa aaaaatcaaa actatttgac
    62941 aaatacaggg acttccgtct attattaacc gtagattaaa tagatcgttc actgagagga
    63001 tctattatat aaacaagaaa actgcaaaat gaatacgtac attgaccaag atcagtaaaa
    63061 aacacgtggt ttagcgagtt cgggagagtg gaagccggac ccaaacgatt tttgaagagg
    63121 cacttgcgag tacgataaat gaagctgccg aatctttatt cggaagtagg gtggaaccgc
    63181 gaaattattc gtccctatgt ctgtaatcag acatagggac tttttgtcgt tttctttcct
    63241 gtattcttat tgacagcaac gcttaaaaat tgaaaggggc aaaacagatg agtaaaaaat
    63301 tgaccgtcca agatatgatt ttaacattac aaaaattttg gtcatcaaac ggctgcatgc
    63361 tgatgcaagc ttatgataca gaaaaaggag caggtacgat gagcccatat acattcttac
    63421 gggcaatcgg accggaacca tggaatgctg cttatgtaga gccatcccgc cgaccagctg
    63481 acgggcgtta tggagaaaac ccaaaccgtt tgtatcagca tcatcaattt caagtcgtaa
    63541 tgaaaccttc acctgaaaat atccaagagc tttatttaga aagcttgcgt cttttaggaa
    63601 ttgatccatt agaacacgat attcgttttg ttgaagacaa ctgggagaac ccatcgatgg
    63661 ggtgtgccgg tgtgggttgg gaagtatggc ttgatgggat ggagatcaca caattcacgt
    63721 acttccagca agtcggagga ctaccttgta aaccagttac ttctgagatc acttatggac
    63781 tagaacgtct tgcttcatat attcaagaag ttgaaagtgt ctatgatctg gaatgggctg
    63841 atggtgtgaa atatggcgag atcttcaaac aaccagaata tgaacattcc aaatattctt
    63901 ttgaagtaag cgaccaagac ttgctactaa gcaattttga ccgttttgaa aaagaagcta
    63961 aacgctgtat cgatgaaaat cttgttcatc cagcgtatga ttatattttg aaatgcagcc
    64021 atacattcaa cttattagat gctcgcggtg cagtatccgt aacagaacga gcaggttatc
    64081 tttcccgtat ccgcaacatg gctcgtgctg tagccaaaat ctttgtggca gaacgcgaaa
    64141 aattaggatt ccctttattg aataaaaaca cagcaaatcc agaaaacatg aaggaggctg
    64201 aataagatgg caaaagactt attacttgaa atcgggctgg aagaaatgcc tgctcatgtt
    64261 gtcacaccaa gcatgaaaca attagaagaa aaaacagcaa aatttttaga tgaaaaccaa
    64321 ttgacttatg atacgatcga aacgttttct acaccgcgcc gcttagcaat caaagtaaca
    64381 aacattccag aacgtcaagc agacagtgaa gaagaagtca aaggaccagc caaaaaaatt
    64441 gctttggacg cagatggaaa ctggacgaaa gcagctgaag gatttgtccg cggacaaggt
    64501 ctgacgacag atgctatcac ttttagagaa ttaaaaggcg tggaatatgt ctatgtaacg
    64561 aaatacactc acggcaaaga agcaaaagaa gtattgacag gtttagcaga tgtcattaaa
    64621 agcctcactt tcccagtaac gatgcactgg gcagaatacg attttgaata tattcgccct
    64681 attcactgga tcgtggcatt gttagatgac gaaataatcc cgtttgagat cttggatgtc
    64741 aaaacagaca gagcttcaag aggtcatcgt ttcttaggcg aagatgtaac atttgcgcat
    64801 gcaaaagaat acgaagaaaa attaaatgaa caatttgtta ttgcttcacc gcaaaaaaga
    64861 aaagaaatga tcatcacaca agcaaacgaa ttagcagaaa aaaatcactg gatcattgat
    64921 ctagatgaag atttactaga agaagtcaac aatctagtcg aatatccaac tgtcttttct
    64981 ggcgacttcg aggaaaaata tctttctgtt cctgaagaag tactagtcac ttctatgaaa
    65041 gaacatcaac gttatttcga agtacggaac gatcaaggta tgttgcttcc tcattttatt
    65101 tctgctcgta atggcgatcg ggtaaaattg gaaaatgtgg tacgaggcaa tcaaaaagta
    65161 ttgactgctc gtttagaaga tgcagaattc ttttataatg aagacaagaa agcttcaatc
    65221 gaccaatacg ttgaaaaatt aaaaactgtt actttccatg aaaaaatcgg tagcatctac
    65281 gagaaaatgc aacgggtaca agtcatcgcc cgcattatag gcgaacaagt aggactatct
    65341 gaggaagaat tgatggatct gcaacgcgct gctgaaatct ataaatttga tctagtaacc
    65401 aacatggtag gagaattccc tgaactacaa gggatcatgg gagaaaaata tgctctgctt
    65461 aaaggcgaga aaccagccgt agcaacagca atccgtgaac attacatgcc tatatccagt
    65521 gaaggagatc tacctgagac tacagtaggt tctgttttag cgattgctga taaattagat
    65581 agtatctttt ctttctttgc agttgggatg atcccaagtg gctcaaacga tccatatgct
    65641 ttgcgccgtc aagcatatgg tgtcgttcga atcatcgaat cgaaaaaatg ggcctttcct
    65701 ttatctgttc tgcaagaaac gattagtgaa gttatcagta aagatgcgga tcgttttggc
    65761 attggcttgt cagcgggaca acaacaggtg atcgacttta tcaaaggccg tctgcgccaa
    65821 ttattgacaa cgaagaatat tcgtcatgat gtcatcgaag ctgttttgaa cgcagaacaa
    65881 aaagatctga caaaagtatt tgcagcagca caattgttca agcagcatct tgcagatgaa
    65941 gacttcaaac catcgatgga agctttgaca cgtgtcgtga acttagcgaa aaaagcggag
    66001 cttgaaaaac aatcagaagt agaccctgaa ctgttcgaaa acgaagcgga gaaagaactg
    66061 tacaaagcag tagagggaat gaaaacaagc tttgctgacc aaacgatcaa cgaaaattat
    66121 gatcagcttg taagccttcg cccactgatc gaaaattatt ttgatcagac gatggtcatg
    66181 gcagaagaac cagcagtacg taagaaccga ttaacgcaat taaatcaaat tgctgccatg
    66241 gctttgtcac tagcaagttt ggatcaaatc atcacaaaat aatttctaat atgtaaataa
    66301 accagagaag aggcacaaaa taggctgttt ctctggttta tttgttataa atataaataa
//
LOCUS       DAKCAA010000009        62023 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000009 DAKCAA010000000
VERSION     DAKCAA010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 62023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62023
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.009"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(285..971)
                     /gene="gpmA"
                     /locus_tag="OUE31_000660"
     CDS             complement(285..971)
                     /gene="gpmA"
                     /locus_tag="OUE31_000660"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCU0221690.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(1143..1724)
                     /locus_tag="OUE31_000661"
     CDS             complement(1143..1724)
                     /locus_tag="OUE31_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCU0221691.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(1857..2540)
                     /gene="rpiA"
                     /locus_tag="OUE31_000662"
     CDS             complement(1857..2540)
                     /gene="rpiA"
                     /locus_tag="OUE31_000662"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HCU0221692.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            2859..3272
                     /gene="rpsL"
                     /locus_tag="OUE31_000663"
     CDS             2859..3272
                     /gene="rpsL"
                     /locus_tag="OUE31_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HCU0221693.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            3356..3826
                     /gene="rpsG"
                     /locus_tag="OUE31_000664"
     CDS             3356..3826
                     /gene="rpsG"
                     /locus_tag="OUE31_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HCU0221694.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            3920..6007
                     /gene="fusA"
                     /locus_tag="OUE31_000665"
     CDS             3920..6007
                     /gene="fusA"
                     /locus_tag="OUE31_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCU0221695.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            6179..7366
                     /gene="tuf"
                     /locus_tag="OUE31_000666"
     CDS             6179..7366
                     /gene="tuf"
                     /locus_tag="OUE31_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCU0221696.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            7773..8081
                     /gene="rpsJ"
                     /locus_tag="OUE31_000667"
     CDS             7773..8081
                     /gene="rpsJ"
                     /locus_tag="OUE31_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HCU0221697.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            8112..8741
                     /gene="rplC"
                     /locus_tag="OUE31_000668"
     CDS             8112..8741
                     /gene="rplC"
                     /locus_tag="OUE31_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HCU0221698.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            8769..9392
                     /gene="rplD"
                     /locus_tag="OUE31_000669"
     CDS             8769..9392
                     /gene="rplD"
                     /locus_tag="OUE31_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HCU0221699.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            9392..9682
                     /gene="rplW"
                     /locus_tag="OUE31_000670"
     CDS             9392..9682
                     /gene="rplW"
                     /locus_tag="OUE31_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HCU0221700.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            9721..10554
                     /gene="rplB"
                     /locus_tag="OUE31_000671"
     CDS             9721..10554
                     /gene="rplB"
                     /locus_tag="OUE31_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HCU0221701.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            10597..10875
                     /gene="rpsS"
                     /locus_tag="OUE31_000672"
     CDS             10597..10875
                     /gene="rpsS"
                     /locus_tag="OUE31_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HCU0221702.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            10898..11245
                     /gene="rplV"
                     /locus_tag="OUE31_000673"
     CDS             10898..11245
                     /gene="rplV"
                     /locus_tag="OUE31_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HCU0221703.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            11259..11915
                     /gene="rpsC"
                     /locus_tag="OUE31_000674"
     CDS             11259..11915
                     /gene="rpsC"
                     /locus_tag="OUE31_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HCU0221704.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            11918..12352
                     /gene="rplP"
                     /locus_tag="OUE31_000675"
     CDS             11918..12352
                     /gene="rplP"
                     /locus_tag="OUE31_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HCU0221705.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            12342..12530
                     /gene="rpmC"
                     /locus_tag="OUE31_000676"
     CDS             12342..12530
                     /gene="rpmC"
                     /locus_tag="OUE31_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HCU0221706.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            12555..12821
                     /gene="rpsQ"
                     /locus_tag="OUE31_000677"
     CDS             12555..12821
                     /gene="rpsQ"
                     /locus_tag="OUE31_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HCU0221707.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            12879..13247
                     /gene="rplN"
                     /locus_tag="OUE31_000678"
     CDS             12879..13247
                     /gene="rplN"
                     /locus_tag="OUE31_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HCU0221708.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            13284..13592
                     /gene="rplX"
                     /locus_tag="OUE31_000679"
     CDS             13284..13592
                     /gene="rplX"
                     /locus_tag="OUE31_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HCU0221709.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            13620..14159
                     /gene="rplE"
                     /locus_tag="OUE31_000680"
     CDS             13620..14159
                     /gene="rplE"
                     /locus_tag="OUE31_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HCU0221710.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            14178..14363
                     /locus_tag="OUE31_000681"
     CDS             14178..14363
                     /locus_tag="OUE31_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HCU0221711.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            14399..14797
                     /gene="rpsH"
                     /locus_tag="OUE31_000682"
     CDS             14399..14797
                     /gene="rpsH"
                     /locus_tag="OUE31_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HCU0221712.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            14829..15365
                     /gene="rplF"
                     /locus_tag="OUE31_000683"
     CDS             14829..15365
                     /gene="rplF"
                     /locus_tag="OUE31_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HCU0221713.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            15526..15882
                     /gene="rplR"
                     /locus_tag="OUE31_000684"
     CDS             15526..15882
                     /gene="rplR"
                     /locus_tag="OUE31_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HCU0221714.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            15903..16403
                     /gene="rpsE"
                     /locus_tag="OUE31_000685"
     CDS             15903..16403
                     /gene="rpsE"
                     /locus_tag="OUE31_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HCU0221715.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            16418..16597
                     /gene="rpmD"
                     /locus_tag="OUE31_000686"
     CDS             16418..16597
                     /gene="rpmD"
                     /locus_tag="OUE31_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HCU0221716.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            16641..17081
                     /gene="rplO"
                     /locus_tag="OUE31_000687"
     CDS             16641..17081
                     /gene="rplO"
                     /locus_tag="OUE31_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HCU0221717.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            17081..18376
                     /gene="secY"
                     /locus_tag="OUE31_000688"
     CDS             17081..18376
                     /gene="secY"
                     /locus_tag="OUE31_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HCU0221718.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            18438..19085
                     /locus_tag="OUE31_000689"
     CDS             18438..19085
                     /locus_tag="OUE31_000689"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HCU0221719.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            19276..19494
                     /gene="infA"
                     /locus_tag="OUE31_000690"
     CDS             19276..19494
                     /gene="infA"
                     /locus_tag="OUE31_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HCU0221720.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            19527..19643
                     /gene="rpmJ"
                     /locus_tag="OUE31_000691"
     CDS             19527..19643
                     /gene="rpmJ"
                     /locus_tag="OUE31_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HCU0221721.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            19661..20026
                     /gene="rpsM"
                     /locus_tag="OUE31_000692"
     CDS             19661..20026
                     /gene="rpsM"
                     /locus_tag="OUE31_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HCU0221722.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            20054..20443
                     /gene="rpsK"
                     /locus_tag="OUE31_000693"
     CDS             20054..20443
                     /gene="rpsK"
                     /locus_tag="OUE31_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HCU0221723.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            20523..21461
                     /locus_tag="OUE31_000694"
     CDS             20523..21461
                     /locus_tag="OUE31_000694"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HCU0221724.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            21489..21869
                     /gene="rplQ"
                     /locus_tag="OUE31_000695"
     CDS             21489..21869
                     /gene="rplQ"
                     /locus_tag="OUE31_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HCU0221725.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            22141..22980
                     /locus_tag="OUE31_000696"
     CDS             22141..22980
                     /locus_tag="OUE31_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCU0221726.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            22956..23825
                     /locus_tag="OUE31_000697"
     CDS             22956..23825
                     /locus_tag="OUE31_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCU0221727.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            23815..24612
                     /locus_tag="OUE31_000698"
     CDS             23815..24612
                     /locus_tag="OUE31_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCU0221728.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            24815..25561
                     /gene="truA"
                     /locus_tag="OUE31_000699"
     CDS             24815..25561
                     /gene="truA"
                     /locus_tag="OUE31_000699"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCU0221729.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(25894..28563)
                     /locus_tag="OUE31_000700"
     CDS             complement(25894..28563)
                     /locus_tag="OUE31_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HCU0221730.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(28801..28989)
                     /locus_tag="OUE31_000701"
     CDS             complement(28801..28989)
                     /locus_tag="OUE31_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HCU0221731.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            29259..29621
                     /locus_tag="OUE31_000702"
     CDS             29259..29621
                     /locus_tag="OUE31_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCU0221732.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            29673..31355
                     /locus_tag="OUE31_000703"
     CDS             29673..31355
                     /locus_tag="OUE31_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HCU0221733.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            31472..33508
                     /gene="recG"
                     /locus_tag="OUE31_000704"
     CDS             31472..33508
                     /gene="recG"
                     /locus_tag="OUE31_000704"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HCU0221734.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            33557..34558
                     /gene="plsX"
                     /locus_tag="OUE31_000705"
     CDS             33557..34558
                     /gene="plsX"
                     /locus_tag="OUE31_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HCU0221735.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            34680..34922
                     /gene="acpP"
                     /locus_tag="OUE31_000706"
     CDS             34680..34922
                     /gene="acpP"
                     /locus_tag="OUE31_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCU0221736.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            35190..36194
                     /locus_tag="OUE31_000707"
     CDS             35190..36194
                     /locus_tag="OUE31_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0221737.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDTELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            36195..37139
                     /locus_tag="OUE31_000708"
     CDS             36195..37139
                     /locus_tag="OUE31_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0221738.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            37139..38101
                     /locus_tag="OUE31_000709"
     CDS             37139..38101
                     /locus_tag="OUE31_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0221739.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            38128..39042
                     /locus_tag="OUE31_000710"
     CDS             38128..39042
                     /locus_tag="OUE31_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0221740.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            39068..40849
                     /locus_tag="OUE31_000711"
     CDS             39068..40849
                     /locus_tag="OUE31_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCU0221741.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            41197..41883
                     /locus_tag="OUE31_000712"
     CDS             41197..41883
                     /locus_tag="OUE31_000712"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HCU0221742.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            41903..45484
                     /gene="smc"
                     /locus_tag="OUE31_000713"
     CDS             41903..45484
                     /gene="smc"
                     /locus_tag="OUE31_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HCU0221743.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            45493..46302
                     /locus_tag="OUE31_000714"
     CDS             45493..46302
                     /locus_tag="OUE31_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCU0221744.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            46313..47311
                     /gene="ftsY"
                     /locus_tag="OUE31_000715"
     CDS             46313..47311
                     /gene="ftsY"
                     /locus_tag="OUE31_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HCU0221745.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            47498..49765
                     /gene="gshAB"
                     /locus_tag="OUE31_000716"
     CDS             47498..49765
                     /gene="gshAB"
                     /locus_tag="OUE31_000716"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HCU0221746.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(49854..50306)
                     /locus_tag="OUE31_000717"
     CDS             complement(49854..50306)
                     /locus_tag="OUE31_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HCU0221747.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            50456..51406
                     /locus_tag="OUE31_000718"
     CDS             50456..51406
                     /locus_tag="OUE31_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCU0221748.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            51399..52358
                     /locus_tag="OUE31_000719"
     CDS             51399..52358
                     /locus_tag="OUE31_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCU0221749.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            52355..53110
                     /locus_tag="OUE31_000720"
     CDS             52355..53110
                     /locus_tag="OUE31_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0221750.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            53133..54086
                     /locus_tag="OUE31_000721"
     CDS             53133..54086
                     /locus_tag="OUE31_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HCU0221751.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(54730..55026)
                     /locus_tag="OUE31_000722"
     CDS             complement(54730..55026)
                     /locus_tag="OUE31_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HCU0221752.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            55381..55737
                     /locus_tag="OUE31_000723"
     CDS             55381..55737
                     /locus_tag="OUE31_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCU0221753.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            55747..56646
                     /locus_tag="OUE31_000724"
     CDS             55747..56646
                     /locus_tag="OUE31_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HCU0221754.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            57163..57894
                     /locus_tag="OUE31_000725"
     CDS             57163..57894
                     /locus_tag="OUE31_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCU0221755.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            58039..60066
                     /locus_tag="OUE31_000726"
     CDS             58039..60066
                     /locus_tag="OUE31_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HCU0221756.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            60174..61271
                     /locus_tag="OUE31_000727"
     CDS             60174..61271
                     /locus_tag="OUE31_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCU0221757.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            61578..>62023
                     /locus_tag="OUE31_000728"
     CDS             61578..>62023
                     /locus_tag="OUE31_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0221758.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        20489 a        11103 c        13216 g        17215 t
ORIGIN      
        1 aagctgccct gcattaagta ataagaacat ccaagcaaaa atagctcctc atgtttttga
       61 cttggctgga cttattattg caaatgtaag cttttgaaca ccgtttacca agaggttgtg
      121 aatctgccgt ttaactctga gtcacaagga acaatttcaa aaaacagctt ttcatgtttg
      181 atgaatattg tgacttgtga ccgagaagtt ggcaggagaa aaccgtttat acgaaaaaag
      241 ggactgtgac aaatcgtgtc acagtccctt ttttatagtg ttttttatag gtagtatttt
      301 ttagcaactg ttaagtcatc atttaattca taaacaagtg gttgacctgt tggaatttca
      361 agatccatga tgtcttcgtc agagatacct tcgatatgtt tagctagggc gcgtaatgag
      421 ttaccatgtg cagctactaa aacagttttg ttgtctagta atgctggagc aatttcatct
      481 tgccagaatg gcaaagcgcg ttctaatgtc actttcaagt tttctccacc aggaatatcg
      541 cgtttgtcta acattgcgta acgacggtca tttgctgcag aaccttcgtc agtttcttcc
      601 attaatggag gaagagtatc gtaagaacga cgccagatgt gcacttgttc gtcgccgtat
      661 ttttcagctg tttctttttt gttcaaacct tgtaatttac catagtgacg ttcgtttaag
      721 cgccatgatt tgatttgtgg tacccaaagt tgatctgaat attctaagat caagttacat
      781 gttttgattg cacgagttaa aacagaagtg taagcaacat caaattcgat tccagcttct
      841 ttgattttgc gtccgccttc ttttgcttct tcgattcctt ctggtgctag atttacatca
      901 gcccaaccag taaattggtt caatgcattc cattcactaa gaccgtgacg agaaaaaact
      961 aattttggca tgtttagctc tccttttaag ataggtttat atttctgaaa ttttcagttc
     1021 tgttttattg tacaattttt tggaagagat ttccatcgaa aaattagata agattctatg
     1081 agaaaacaag tagagaatat aaaaaaacga acagtgccca cgcaactgtt cgtttttagg
     1141 tattagatgc ataattgctc gatttctttt tcaggtaaat tgatatattt ataacatgtt
     1201 ccaactgaaa caccgcattt tgaagaaata aattggatcg tttctttttt ttcataatag
     1261 agacgtcgga tttttttgat cgtttttgca tcgatttttg gtcttccgcc gatttttcct
     1321 tttttacgag cttcatctaa tccaactaat gtacgttctt tgatcaatgc gcactccatg
     1381 tttgctaggt tttccattaa ttggaaatag atttttccca tttcgcgcgt atcgattcct
     1441 tcatcaagac taatcaagtg cagcccgcga tctttgaata attgcgtgag ttctgttaat
     1501 tgccgcgtag atttgcctaa tcgatgaagt tggcaaatga ctagtgcatc gccttgttgc
     1561 atgtcagcga tcactgactc caaatgaaca gcagtagaat cattttgttc cacttcatat
     1621 gtctcatgga aaatttcttg acaaccaaag tcagataatt gatcaacctg agttgttaaa
     1681 tcaacgtcat ttatggttgt gcgtgcataa ccaataattt tcatggtgat tcctttctag
     1741 cagtgatttt ctaactggat ataacagtaa aaatgtagca taaagtacgt caaaaagata
     1801 gttttttcgc aaattttccg ctgtcttttt ttattggatg atcaagcagt ttttctttat
     1861 ttacgacgga ttgcgtcaag aatctcaacg cctttttctg agccgacaac tactttagaa
     1921 accatgttta ggaaaagccc atgttctact accccaacaa gttcatctaa ataggtagct
     1981 aagctttctg gctgttcgat gacttctaga tgcagatcaa tgatgtaatg accaccatct
     2041 gtggttaaga cttctccgtt ttcgtctgta cgcaagacgg gttggaatct tttttcttca
     2101 aaaatatgaa gtagctgttg ggagccataa gggatcactt caactgggag tgggaacttc
     2161 ccaagtttat cgactaattt agaagaatca acgatccaaa tcgtttcttt tgagtacgta
     2221 gcgactattt tctcgaaaag caaagcagcg ccgccgcctt tgatcccttg aaaatcagca
     2281 ctgatttcat cagcaccgtc tattgtcaaa tcgactacgg ggacttcatc aatactcttt
     2341 aacggtattc ctaatttttc cgcttgttct tttgtcgcat ttgaagtagt aactcctgtg
     2401 atacgtaaac cttcttcacg catacggcga ccaatctctt ctaccatata ataggcggtt
     2461 gaaccggtcc cgagacctac gatcatcccg tcctttacga atttcgcggc ttcaatgcca
     2521 gctaattgtt ttaaattcat ctttgcgtcc accttttttt agtttgagca tcgtgctttc
     2581 ctcactattt tagcgtgatt tacggtaaaa agataccatt cttttttatt ccaataaagc
     2641 tttttcaaaa aaaattgcat ctcttgttga catgtttttt cattcgtgat attctaacaa
     2701 aggtgcttta tctacaggtt tctgtgaaga aacgtgctga ctgtttatca aagcatattt
     2761 gataaggatg cagacattgc atttattttt tatcacaaaa aaagaaccac ctggatgtgt
     2821 ggaactagac gcaaatcgtg ggaaggagga aacaaggaat gcctacaatt aaccaattag
     2881 tacgtaaacc tcgtaaatca aaggtggaaa aatctaattc acctgctttg aacaaaggat
     2941 ataacagctt taagaaaact caaactaacg taaactcacc tcaaaaacgt ggggtagcaa
     3001 ctcgtgtggg tacaatgaca cctaaaaaac cgaactcagc tttacgtaaa tatgcacgtg
     3061 ttcgtttgtc aaacttaatt gaagttactg cttatatccc agggattggt cataacttac
     3121 aagaacacag tgttgtatta ttacgcggtg gtcgtgtaaa agacttacca ggggtacgtt
     3181 accatatcgt tcgcggtgct ttagatactg ctggtgttaa cgaccgtaaa caaagccgtt
     3241 ctaaatacgg aactaaaaaa cctaaagctt aattttaatt attaaacaaa tgaaacttgc
     3301 ttctactata tagaagtaat tactatgaac aatatttcgg aaggaggagt tacggatgcc
     3361 acgtaaaggt cctgttgcaa aacgtgatgt tttaccagat cctatttata actcaaaatt
     3421 agtaactcgc ttgatcaacc gtgtaatggt tgacggaaaa cgcgggattg cagctaacat
     3481 tatctataat gcctttgact tgatcaaaga atctacaggt aacgatccat tagaagtgtt
     3541 tgaacaagca atgaaaaacg ttcaacctgt tcttgaagtt aaagcacgtc gtgttggggg
     3601 ttcaaactac caagtaccag ttgaagttcg ccctgaacgc cgcgttactc taggtcttcg
     3661 ttgggtagta aactacgctc gcttgcgcgg tgaacacaca atggaagaac gcttagcaaa
     3721 agaaatcatg gatgctgcaa acaacacagg tgcttctgtt aaaaaacgtg aagacactca
     3781 taaaatggct gatgccaacc gtgcgtttgc tcactatcgc tggtaagatt ctctctgttt
     3841 ggtcggcttt tataagtcga cctcagatag tgtccttatt tttagcaact agatagtaaa
     3901 gagaggagaa acaaggagaa tgaccagaga attttcttta caaaacactc gtaatatcgg
     3961 tatcatggcc cacatcgatg ctggtaaaac gactgctact gaacgtatct tgtactatac
     4021 tggtaaaatc cataaaattg gtgaaactca tgaaggagct tcacaaatgg actggatgga
     4081 acaagaacaa gaacgtggta ttacgatcac ttctgctgct actacagcac aatggaaggg
     4141 tcaccgaatc aacatcatcg acacaccagg acacgtagac ttcacagttg aagttgaacg
     4201 ttcattgcgt gtacttgatg gtgctgtaac tgttcttgat gcacaatcag gtgttgaacc
     4261 tcaaactgaa acagtttggc gtcaagcaac aacttatggt gtacctcgta tcgtatttgc
     4321 aaacaaaatg gacaagatcg gtgctgactt cttatattca gtatcaactt tacatgaccg
     4381 tttgcaagca aacgctcacc caatccaatt accaattggt gcggaagacg acttcacagg
     4441 aattatcgac cttgtaacaa tgaaggctga aatgtataca aacgatcttg gaacagagat
     4501 cgaagaaaca gaaattcctg aagaataccg cgaattagct gaagaatggc gcgaaaaatt
     4561 ggttgaagct gtagctgaaa ctgatgaaga acttactttg aaatacttag aaggtgaaga
     4621 aatcactgaa gctgagttaa aagaaggtat ccgccgcgca acagttaacg tagaattcta
     4681 cccagtacta tgtggttcag catttaagaa caaaggggtt caattactat tggacgctgt
     4741 tcttgattac ttgccatcac cgttagatat cccagctatc aaagggattg accctaaaac
     4801 tgatgaagaa gtagaacgtc ctgcagacga cagcgctcct ttctcagctt tagcatttaa
     4861 agttatgact gacccattcg taggtcgttt aactttcttc cgtgtgtact ctggtgtttt
     4921 acaatcaggt tcatacgtac aaaacgcaac aaaaggcaaa cgtgaacgtg ttggtcgtat
     4981 cctacagatg catgccaact ctcgttcaga aatctctgaa gtttacgctg gagatatcgc
     5041 tgctgctgtt ggtttgaaag acacaactac tggggacaca ctatgtgatg aaaagagtct
     5101 agttattctt gaatccatgg aattcccaga accagttatc caagtcgcta ttgaacctaa
     5161 atcaaaagct gaccaagata aaatgggtgt ggctttacaa aaactatctg aagaagatcc
     5221 tactttccgt gctgaaacaa acgtggaaac aggcgaaaca atcatcgctg gtatgggtga
     5281 acttcactta gatatcatcg ttgaccgtat gcgtcgtgaa ttcaaagttg aagctaacgt
     5341 aggtgcgcct caagtatctt accgtgaaac tttccgtgct ggcactcaag ccgaaggtaa
     5401 gtttgtacgt cagtctggtg gtaaaggtca atacggtcac gtatggattg aatttacacc
     5461 aaatgaagaa ggtgctggtt tcgaatttga aaatgcgatc gtcggtgggg ttgttcctcg
     5521 tgaatacatt ccagctgttg aaactggttt gaaagatgct atggaaaatg gtgtcttagc
     5581 tggctatcca ttagtagata tcaaagctaa actttacgat ggttcatacc atgatgtcga
     5641 ttcaaatgaa actgccttcc gtgttgctgc ttctatggca ttacgtgcag cagctaagaa
     5701 agctaatcca gtaatccttg aaccaatcat ggctgtagaa gttgttatcc ctgaagatta
     5761 tttaggtgat gttatgggtc acgtaactgc tcgtcgtgga cgtgttgaag gtatggaagc
     5821 tcgcgctggc ggccaacaag ttgttcgtgc gatggttcca cttgctgaaa tgtttggtta
     5881 tgctacaact cttcgttctg ctactcaagg tcgtggtaca tttacaatga catttgacca
     5941 ctacgaagat gtaccaaaat cagtacaaga agaaatcatt aagaaaaacg gcggaaaagc
     6001 tgaataattt cttaaaaccg gatagtcctg caaagagatt atccaaagag actatatttt
     6061 taatatagtt tcgtgtaaaa taattatcga tgatatgggc atgtggtgta ccttgtgtac
     6121 atcatatacc tatcagacaa ataaaaaata tattgtattt ttaggaggac attttaaaat
     6181 ggcaaaagaa aaatttgacc gttctaaacc acacgttaac attggtacta tcggacacgt
     6241 tgaccatggt aaaactacat taacagctgc aatcacaact gtactatcta agaaaaacgg
     6301 cggccaagct atggcttacg atcaaatcga tggtgctcca gaagaacgcg aacgcggaat
     6361 cacaatctca acagctcacg ttgagtatga aacagataca cgccactacg ctcacgttga
     6421 ctgcccagga cacgcggatt acgttaaaaa catgatcact ggtgctgctc aaatggacgg
     6481 agctatcttg gtagtttctg ctgctgacgg cccaatgcct caaactcgtg aacacatcct
     6541 attgtctcgt caagttggtg ttccttacat cgttgtattc ttgaacaaag tagacatggt
     6601 tgatgacgaa gaattactag aattagttga aatggaagtt cgtgacctat taacagaata
     6661 cgaattccct ggtgacgatg ttcctgtagt tgctggatca gctttgaaag ctctagaagg
     6721 cgacgcttca tacgaagaaa aaattcttga attaatggct gcagttgacg aatacatccc
     6781 aactccagaa cgtgacaacg acaaaccatt catgatgcca gttgaagacg tgttctcaat
     6841 tactggacgt ggtactgttg ctacaggtcg tgttgaacgt ggacaagttc gcgttggtga
     6901 cgaagttgaa gttgttggta ttgctgaaga aacttcaaaa acaacagtta ctggtgttga
     6961 aatgttccgt aaattgttag actacgctga agctggagac aacattggtg ctttactacg
     7021 tggtgttgca cgtgaagaca tccaacgtgg acaagtttta gctaaaccag gtacaatcac
     7081 acctcataca aaattctctg cagaagtata cgtgttgaca aaagaagaag gtggacgtca
     7141 tactccattc ttcactaact accgtccaca attctacttc cgtacaactg acgtaacagg
     7201 tgttgttgaa ttaccagaag gaactgaaat ggttatgcct ggcgacaacg taacaatgga
     7261 agttgaatta atccacccaa tcgctatcga aaacggtact aaattctcaa tccgtgaagg
     7321 cggacgtaca gttggtgccg gtgtcgttac agaaatcaaa gcttaattca cttaagtttt
     7381 aaagtaaagc aacatttatt cggacgtaat cgctcggaac gaaggtctta ggatctttgt
     7441 tccgagcttt tttatttatt gcaggatcag gaaaaaagac aggagtatta taaatagaag
     7501 aaacacgaaa taaaagagtc agtattttct aaatgaaact ttatgaaaac aaaatgtttt
     7561 ttacaagaaa aagccttgct ttgtgagttt atatatatta taatgacaaa ggtgcgttta
     7621 ctttagtgaa ttgcacagac gtaatcagaa tgatttcgtc ggctaagaaa cgagaggttg
     7681 cgacacgccc ggacgctttg ccacgaacga gcgtgacgga aattttcgtg gagctatgtc
     7741 tacttttcaa aataggcgaa ggagggaaca agatggcaaa acaaaaaatt cgtatccgtt
     7801 taaaagcgta tgaacaccgt attttagatc aatcagcgga taaaatcgtg gaaactgcaa
     7861 aaagaactgg agctagcgtg tctggtccaa ttccattacc aactgaacgc agtctttaca
     7921 caatcatccg tgcgactcat aaatacaaag attcacgcga acaattcgaa atgcgtacac
     7981 acaaacgtct tatcgacatt gtgaacccaa caccaaaaac tgttgatgct ttgatgaagc
     8041 tagacttacc atctggtgta aacatcgaaa tcaaattata aaactaaaac aaaaataatg
     8101 gaggtgtact catgaccaaa ggaatcttag ggaaaaaagt gggaatgaca caaatcttca
     8161 ctgaatctgg tgaattaatt ccagtaactg ttgtagaagc tactccaaac gtagtactac
     8221 aagtgaaaac aatggaaacg gatggctacg aagctattca agttggttac caagatatgc
     8281 gtgaagtttt atcaaacaaa cctgcgaaag gtcatgttgc aaaagcaaac acggctccta
     8341 agcgcttcat tcgtgaattc aaaaatgttg agctaggaga atatgaagta ggaaaagaaa
     8401 ttacagtaga tgttttccaa gcaggagaca ttattgatgt aacaggtact acgaaaggta
     8461 aaggattcca aggggttatc aaacgccacg gacaaagccg cggaccaatg gctcacggtt
     8521 ctcgttacca tcgtcgtcct gggtcaatgg gtccagttgc acctaaccgt gtatttaaaa
     8581 acaaacgtct tgctggccgt atgggtggca accgcgtaac tatccaaaac ttggaagttg
     8641 tacgtgtcga tgcagaaaga aatgttatct tgatcaaagg taatgttcct ggagctaaaa
     8701 aatctttaat tactatcaaa tcagctgtga aagctaaata attgtaggaa gaaaggagga
     8761 actaaggaat gccgaatgta gcattattca aacaagatgg aagccaaaac ggtgaaatca
     8821 cacttaacga agaaatcttc ggaattgaac ctaatgaaag tgttgtttac gatgcaatcg
     8881 taatgcaacg tgcgtcatta agacaaggaa cacacgcggt taaaaaccgt agcgctgttc
     8941 gcggcggcgg acgtaaacca tggcgtcaaa aaggaacagg tcgtgcacgt caaggatcta
     9001 tccgctcacc acaatggcgt ggaggtggcg tagtctttgg accaacacca cgttcttaca
     9061 gctacaaact tcctaaaaaa gttcgtcgtt tagcaatgaa atctgtattg tcagaaaaag
     9121 ttgctgaaaa caacttggta gcaatcgaag gcttgaactt cgacgcacca aaaacaaaag
     9181 aattcaaaca agttcttgct aacttatcta tcgactctaa agtattggtt gttctagaaa
     9241 aaggtaacga ctttgctgct ttatcagcac gtaacttacc aaacgtttct gtagtaactt
     9301 ctgataatgt gagtgtgcta gacgttgtat caaatacaaa agtgttagca acacaaactg
     9361 ctcttactca aattgaggag gtgcttgcat aatgaactta ctagacgtaa tcaaacgccc
     9421 agtgatcact gaaaaatcaa tgcttgccat ggatgacaag aaatacactt ttgaagtgga
     9481 cactcgcgca aacaaaactt tagtaaaaca agcggtagaa gctgcttttg acgttaaagt
     9541 caaaaacgtg aacatcgtga acgtacgtgc gaaattcaaa cgtatgggca aatatgcagg
     9601 atatacaaaa aaacgtcgca aagcgatcgt tacattgact gaagattcaa aagaaatcca
     9661 attattcgaa gctgctgaat aagcactaat agataactca ttaaattagg agggaaaaac
     9721 gtggcgatta aaaagtacaa acctacctca aatggtcgtc gtaacatgac aggttctgat
     9781 tttgctgaaa tcacaacatc aacacctgaa aaatcattgt tacaaccatt gaaaaaccat
     9841 gctggacgta acaacaacgg ccgcatcact gtacgtcatc aaggtggcgg acacaaacgc
     9901 caatatcgcg tgatcgactt caaacgtaac aaagataacg ttgttgcaac tgttcaaacg
     9961 atcgaatatg atccaaaccg ttcagctaac atcgcgttag tacactatga agatggagtg
    10021 aaagcttaca tcttagcacc taaaggacta gaagtgggta tgaaacttgt ttcaggtcca
    10081 gaagcagata tcaaagtcgg aaatgctctt ccattagaaa acattccagt tggtactgtt
    10141 atccacaaca ttgaaatgaa acctggtaaa ggtggacaat tgatccgttc tgctggtaca
    10201 agtgctcaag tacttggtaa agaaggcaaa tacgtattga tccgcttgaa ctctggtgaa
    10261 gttcgtatga tcttagctgc atgccgtgct acaatcggtt ctgtaggtaa cgaacaacac
    10321 gaattaatca acatcggtaa agctggacgc tctcgttgga tgcgtaaacg cccaactgta
    10381 cgtggtagcg taatgaaccc taatgatcac ccacacggtg gtggtgaagg taaagctcct
    10441 atcggacgta aagcaccagt ttctccttgg ggtcaaccag ctcttggtta caaaactcgt
    10501 aacaaaaaag ctaaatcaga caaacttatt gttcgtcgtc gcaaaaataa ataattactt
    10561 tgaccatgtg tcgcacattt tgagaggagg ttcaccatgg gtcgtagttt aaagaaagga
    10621 ccttttgtcg atgagcattt aatgaaaaaa gttgaagctc aagcaggggt tgaaaagaaa
    10681 aaagttatca aaacttggtc acgccgttca acagttttcc caagttttgt tggatatacc
    10741 atcgcagttt atgatggacg taaacatgta ccagtttaca tccaagaaga catggtagga
    10801 cacaaattag gtgaatttgc acctacaaga acttatcgtg gacatgctgc tgacgataag
    10861 aaaacgaaac gctaatttga ggggaggata aatccaaatg gcagaacaaa tcacatcagc
    10921 taaagcaact gcaaaaacag ttcgcacttc acctcgaaaa gcccgtttag taattgacct
    10981 tatcagaggt aaaagtgtcg cagatgcaat ttcaatcttg aaattcacac caaacaaatc
    11041 tgctggaatc attgaaaaag tattgatgtc agcagttgcg aatgcagaaa ataactttga
    11101 cttagatgtt gaaaacttgg tagtaagcga agcttttgtt aacgaaggac ctacaatgaa
    11161 acgtttccgt cctcgtgcaa aaggatcagc ttctccaatc aacaaacgta caagtcatat
    11221 cacggtagtc gtatcagaaa aataaggagg gataatcagt gggtcaaaaa gtacatccaa
    11281 ttggaatgcg tgtaggcatc atccgcgact gggatgctaa atggtatgct gaaaaagagt
    11341 atgctgagtt cttacacgaa gatttaagaa tccgtaaatt tatttcaact aaacttgctg
    11401 atgctgctgt atcaacagtt gaaatcgaac gcgcaacagg tcgcgtaaac atttcaattc
    11461 acacagctaa accaggtatg gttattggta aaggcggttc tgaagtcgaa agcctaagaa
    11521 aagaattaaa caaattaact ggtaaaagaa tccatatcaa tatcgtggaa atcaaaaaac
    11581 cagatctaga tgcaaaatta gtaggtgaag gaatcgcacg tcaattagaa aaccgtgttg
    11641 ctttccgtcg cgctcaaaaa caagccatcc aacgctcaat gcgtgctggc gctcaaggga
    11701 tcaaaactca agtatctggt cgtctaaacg gagcagatat cgctcgttca gaaggatact
    11761 cagaaggaac tgttcctctt catactttac gtgcggacat tgattacgca tgggaagaag
    11821 cagatacaac atacggaaaa ctaggagtta aagtgtggat ctatcgtgga gaaattcttc
    11881 caactaaaaa aaacactgag aaaggaggga aataatcatg ttagtaccta aacgtgtaaa
    11941 acaccgtcgt gaattccgcg gaaaaatgcg cggggaagct aaaggcggaa aagaagtagc
    12001 attcggtgaa tacggtttgc aagctgttga ttcacattgg atcacaaacc gccaaatcga
    12061 agctgctcgt atcgcaatga ctcgttacat gaaacgtggt gggaaagtat ggattaaaat
    12121 tttccctcac aaatcttata ctgccaaagc aattggggta cgtatgggtt ctggtaaagg
    12181 ggcacctgaa ggatgggttg caccagtaaa acgtggtaaa atcatgtttg aaatcgcagg
    12241 cgttcctgaa gaagtagctc gtgaagcgtt acgtctagct tctcacaaat taccaatgaa
    12301 aactaagatc gtaaaacgtg aggaaatggg tggtgaatcg aatgaaggtt aaagaaatca
    12361 gagaattaac cactgccgaa atgcttgatc aagaaaaaca attaaaagaa gaattgttta
    12421 atcttagatt ccaattagca acaggtcaat tagaaaacac tgcacgtatt aaagaagtac
    12481 gtaaatcgat tgcacgcatc aaaactgtgt tgcgtgaaca agctaagtaa ttatggaagg
    12541 aggccattaa gcgtatgact gaaggaagaa atcaacgcaa agtttatcaa ggtcgcgtgg
    12601 tttcagacaa aatggataaa acaattaccg ttgctgtcga aacaaagaaa aaccacccta
    12661 tctatggcaa acgcatgaac tattctaaga aatacaaagt gcatgatgaa aacaacacag
    12721 caaaagttgg cgacatcgtg agaattatgg aaactcgtcc attatcagct acaaaacgtt
    12781 tccgtttgtt ggaagtagtc gaagaagcag ttattatcta ataacacgag attttcctat
    12841 atagattgaa tgcaaaatct gaaaggagga tacacaacgt gatccaagca gaaagtcgtt
    12901 taaaagtcgc tgataactca ggcgcacgtg aaattttgac gatcaaagtc cttggtggat
    12961 ctggtcgtaa aactgctaac atcggtgatg tgatcgttgc tacggttaaa caagcaacgc
    13021 caggtggggt tgtcaaaaaa ggtgacgtcg ttaaagccgt tatcgttcga acaaaatcag
    13081 gagctcgtcg tacagacggt tcatatatta aatttgatga aaatgctgca gtgattattc
    13141 gtgatgataa aagccctcgt ggaacacgta tctttgggcc agttgcacgt gaactacgtg
    13201 aaaacaactt catgaagatc gtttcactag caccagaagt tttataatct tgagacactt
    13261 atcaaaggag gtgcgaaaca gttatgtttg ttaaaaaagg cgataaagtt aaagttatca
    13321 ctggaaaaga caaaaacaaa gaaggcgttg tactagcagc gttcccgaaa aaagataaag
    13381 ttattgtcga aggtgtaaat gtcgttaaaa aacaccaaaa accttctcaa gctgctcctc
    13441 aaggtggaat tgttgagatg gaagcgccaa ttcatgtttc taacgtgatg gtggttgact
    13501 ctactggtgt agctggccga gttggctaca aagaagtaga cggcaaaaaa gtccgtgttt
    13561 ctaaaaaaac cggtgaagtt ttagataaat aaaagtttaa ggaaggaggg tcttactgaa
    13621 tgaaccgcct aaaagaaaaa tatcttaaag aagtaactcc atcattgatg gaaaaattta
    13681 actatagctc tgttatgcaa acacctaaag ttgaaaaaat cgtcatcaac atgggtgttg
    13741 gtgatgcggt atcaaacgct aaaaacttag ataaagcagt tgaagaatta actttgatca
    13801 ctggtcaaaa accaatgatt acaaaagcta aaaaatcaat cgctggattc cgtttacgtg
    13861 aaggaatgcc aattggtgca aaagttacat tgcgcggaga aagaatgtac gaattcttag
    13921 acaaattggt ttctgtttca ctaccacgtg tacgtgactt ccatggtgta agtaaaaaag
    13981 cctttgacgg tcgtggaaac tatactttag gtattaaaga acaattgatc ttcccagaag
    14041 tagattatga tttagtagat aaagtacgtg gtatggacat cgttattgta acaacagcaa
    14101 actctgatga agaatctcgt gagttgttga cacaattagg catgccattc caaaaataat
    14161 taaaggaggc gaactacgtg gctaaaaaat caatgattgc taaaaacaaa cgtcctgcaa
    14221 aattttcaac acaagcttat actcgttgcg aacgttgcgg acgtccacat tcagtttatc
    14281 gtaagttcca tctttgccgt atttgcttcc gcgaacttgc ctataaaggt caaattcccg
    14341 gcgtgaagaa agctagctgg taaaaagtaa attcgcataa gaaggaggta aaagatcaat
    14401 ggtcatgaca gatccaattg cagattttct aactcgtatc cgtaacgcaa acatggttaa
    14461 acatgagtct ttagaagtac ctgcatcaaa aattaaacgt gacatcgctg aaatcttgaa
    14521 acgtgaaggt ttcgttcgtg atgttgaata catcgaagat gacaaacaag gcgtgatccg
    14581 tgttttccta aaatttggta aaaacggcga acgtgttatc acaaacttaa aacgtatctc
    14641 taaaccaggt ttgcgtgctt atgtcaaagc tgacgaagta ccaaaagtat tgaacggttt
    14701 aggtatcgca atcatttcga cttctgaagg tgttgtcact gataaagaag ctcgtgaaaa
    14761 aaatatcggc ggcgaagtta tcgcttacgt atggtaatca agtagaatct acaaggaggt
    14821 gtctttaagt gagccgtatc ggaaataaag tcgttgttat ccctgaagga gtaacagtta
    14881 ctcaagacgg aaacaacgtt acagttaaag gaccaaaagg tgaattgact cgtacttttt
    14941 cagcagatat caaaatgaat atcgaaggaa acgaagtaac tttcactcgt ccaaacgaca
    15001 gtaaagaaat gaaaacaatt catggaacaa ctcgtgcgaa cttcaacaac atggttgtag
    15061 gtgtcagcga aggtttccaa aaagcgttag aactaatcgg ggttgggtac cgtgcacaat
    15121 tacaaggatc aaaacttgta ttgaacgttg gttactcaca tccagtagaa atcacaccac
    15181 cagctggagt aactgttgaa gtaccagcta acacacaagt aattgttaaa ggtgcgaaca
    15241 aagaagaagt tggcgaatta gctgcaaaca ttcgtggaac tcgtcctcca gaaccttata
    15301 aaggtaaagg tattcgttat gttggcgaat atgtacgccg taaagaaggt aaaactggta
    15361 aataatcgtt tagaaaaatt gcatagaagc cagcagcagg aaaaaggcat ttggctgaag
    15421 tttaccttca aaaaaataca tttttacttg tgccgcagct tctatttttc gaaacgtatt
    15481 tactgcttga aatagtagta caataaaaat aaagaggtga caattgtgat tacaaaacca
    15541 gataagaaca aaacacgtca aaagagacat cgtcgtgtac gtaacaatat ctctggtact
    15601 gctgagcgcc cacgcttgaa cgtttttcgt tctaacaaaa acatctacgc tcaaattatt
    15661 gatgacgtag cgggtgtaac gctagcaagt gcctctacct tggataaaga aatttcaggt
    15721 ggaacaaaaa cagaagcagc acaagctgtc ggtaaactag ttgctgaacg cgcagctgaa
    15781 aaaggcatta aagtagtagt ctttgaccgt ggtggatacc tttaccatgg ccgtgtgcaa
    15841 gctttagctg aagctgctcg cgaaaatgga ctagaatttt agaagaagga ggaataccat
    15901 tcatggttta tatcgatcca aaacatttgg aattagaaga ccgcgttgtt gcaattaacc
    15961 gtgtaacaaa agttgttaaa ggtggacgtc gtctacgttt tgctgcttta gttgttgtcg
    16021 gtgacaaaaa cggacacgta gggtttggta caggtaaagc tcaagaagtt cctgaagcaa
    16081 tccgtaaagc aattgaagat gcgaagaaaa acttagttga agtacctatg gttggttcaa
    16141 caatcccaca cgaagtaatc ggtgctttta gtggtggtag aatcctaatg aaacctgctg
    16201 tagaaggttc tggggttgct gctggtggac cagttcgtgc cgtattagaa ttagctgggg
    16261 tagcagatat cacttctaaa tctttaggct caaatacacc aatcaacgtt gttcgcgcaa
    16321 cagttgaagg tttgaaacaa ttgaaacgtg cagaagaagt tgcagaactt cgcggcaaat
    16381 cagttgaaga attaatcgga taaggaggac aacaataatg gctgaattaa aagttacttt
    16441 aaaacgcagt attatcggac gtcctcaaaa ccaacgcgat acagttaaag cgttaggtct
    16501 tacaaagatt aacagttcag tggttaagcc ttctaatgaa gcaattaaag gcatgatcaa
    16561 tactgtttct cacctagtgg acgttgaaga aatttaattt agaaaaatca taactagaac
    16621 attaaggagg tgccaaacct atgaaacttc atgaattaaa acctgctgaa ggttcacgcc
    16681 aagtacgtaa ccgtgttggt cgtggtactt catctggtaa cggaaaaact gccggacgcg
    16741 gacaaaaagg acaaaaagct cgttcaggcg gcggtgtgcg tttaggattt gaagggggac
    16801 aaacaccatt gttccgtcgt ttaccaaaac gaggattcac aaacgtgaac cgtaaagact
    16861 atgcagtcat taatcttgat gtattgaacc gctttgaaga cggagctgaa gtaactcctg
    16921 ttgctttagt tgaagctgga atcgtgaaaa acgaaaaagc tggaatcaaa gtattagcta
    16981 atggggaact aaacaagaaa ttaactgtga aagcagcaaa attctctaaa gcagctcaag
    17041 aagcaattga agcggctggt ggatcaatcg aggtgatcta atgtttagac tattaaaaga
    17101 tgcttttaaa gtaaaagaca ttagatcgaa aatcctattt actgtatttg tgttgtttgt
    17161 atttcgccta ggtgcacata ttactgtacc aggcgtaaat gctgcttcat tgcaaaacct
    17221 ttcttctttg ccatttttca acatgttgaa cttggtaagt ggtagtgcga tgcaaaactt
    17281 ttccattttc tcaatggggg tttcaccata cattactgct tctatcgtca ttcagcttct
    17341 tcaaatggac atcgtgcctc gatttgttga atggtcgaaa caaggggaag ttggtcgtaa
    17401 aaaactgaat caagcgactc gatatctgac attagtattg gcatttatcc aatctgtcgg
    17461 tatcactgct ggattcaatc aatacgctca attaggtttc gtgaataatc ctaacgtagc
    17521 aacttacgta acgatcggtt tgattctaac agccggtacg atgtttgtta cttggctagg
    17581 agaacagatc acagaaaaag gtatcggaaa tggcgtatca atgatcattt ttgcaggtat
    17641 catttctaga ttgcctgaaa gtatcagaga aatttatgaa gattacttta taaatattga
    17701 tccttcagac atatggaaat ctgctatttt tgtggccatt ttactagtag cggtcttgtt
    17761 gatcgtgaca ttcgtaacat ttttccaaca agctgaacgc aagatcccga tccaatatac
    17821 gaaacgcgta gctggcgcgc ctacaagcag ctatctgccg ttgaaagtaa atgcagctgg
    17881 agttattcca gttatctttg ctagttcgtt tattgctacg ccaaatgctg ttttacaagc
    17941 attgagcggt agattcggtt ctgaaaactg gtacaaagtg atgatggaga tctttaacta
    18001 taatacagca cctggtgcta cgatttatac gattctgatc gttgccttca ctttcttcta
    18061 cgcctttgtt caagtaaacc ctgagaaatt agcggaaaac ttgcaaaagc aaggaagtta
    18121 tataccaagc gtacgccctg gtaaggggac tgaagagtat gtctcaagat tactgatgcg
    18181 tttaagtaca gttggtgcag tcttccttgg tttagtggca ttgcttccaa tcattgctca
    18241 aatggtttgg gatcttccac aatcaatcgg attaggcggt acaagcttac tgatcgttat
    18301 cggtgtagct ttagaaactg cgaaacagtt agaaggctta atgctgaaac gtaaatatgt
    18361 tggattcatt gagtaagaaa gcgtgttgag gtttcccctc aacacacgtt ctcacacatt
    18421 tattaggagg gaaaacaatg aacctcattt taatggggct gccaggcgca ggtaaaggaa
    18481 cacaagctga aaaaatcatt gatgcttatg gtattccgca catctcaaca ggagatatgt
    18541 tccgcgcagc gatgcaaaac gaaacagctc ttggcctgga agcaaagtct tatatggata
    18601 aaggtgcatt agttcctgat gaagtaacaa atggaatcgt gaaagagcga ctagctgaac
    18661 cagatacaga gaaaggcttc ttattagatg gctttccacg tacgctagat caagcaaaag
    18721 ctctggacgc aatgctaaaa gatttgaata aaaaaattga tgctgtcatc gatatccatg
    18781 ttggtgaaga aatcttggtc gaacgtctag ccggccgatt tatctgcagc aattgtggag
    18841 caacttacca taaaattttc aaccctacaa aagttgaaga cacatgtgat cgttgcggtg
    18901 ggcatgaatt ctatcaaaga gaagatgata aacctgagac ggttaaaaat cgtctggcta
    18961 tcaacatcaa aaatagtgaa ccaatcttgg cttattataa agaacaaggt ttgctaaaca
    19021 ctattgatgg tgctcgtgaa atcgatgctg tatttgcaga tgtacaaaaa atcattgaaa
    19081 aatagcacga ttgcccgtag ccgacttgca ttatgcagtt actcttgtca agttcaataa
    19141 attatgatag aatatgtcag tccgacttct agagaatcct ctagatgatc cattttgaga
    19201 attttgaggt gggaactgca gtttccgcca ttttatcgtg tgaaaatgcg aaacaagtac
    19261 aaggaggtac tgtgcgtggc aaaagaagat atgattgaag tcgaaggtac agtcgtcgaa
    19321 actttgccga atgcaatgtt taaagttgaa ctagaaaacg gacaccaagt tcttgctact
    19381 gtttcaggta aaattcgtat gcattacatc cgtatcttac ctggtgacaa agtaacggtt
    19441 gaattgtctc catacgatct taaccgtggc cgtattactt atcgctttaa ataattgtac
    19501 tccgtaaaac tacaggaggt attatcatga aagtaagacc atcagtaaaa ccaatgtgcg
    19561 aacattgtaa agtaattcgt cgtaaaggac gcgttatggt gatttgccca gcaaatccaa
    19621 aacataaaca acgtcaagga taattggagg tgctataaat atggctcgta ttgcaggagt
    19681 agatattcct cgtgataaac gtgtagtagt ttcacttact tatatctatg gtattggtaa
    19741 cactactgct aaaaagatct tagctgatgc tggtgtatct gaagatgttc gcgttcgtga
    19801 attaacgaat gaacaaacag atgctatccg tgcagaagta gataaattaa aagttgaagg
    19861 ggatcttcgt cgtgaagtga acttgaacat caaacgtttg atggaaatcg gttcttaccg
    19921 tggaatccgt catcgccgtg gattgcctgt tcgtggacaa aacacgaaaa acaatgcacg
    19981 tactcgtaaa ggcccagctc gcgctatcgc tggcaagaaa aaataattct taagtgaagg
    20041 aggttaaaac ttcatggcag caaaaaaagt gaatcgtaaa cgccgtgtga agaagaatat
    20101 agaagcaggt attgcacata tccattctac attcaataac actatcatca tgatcactga
    20161 tactcacgga aatgcattag cgtggtcatc agctggttca ttaggtttca aaggaagcaa
    20221 aaaatcaact ccttttgccg ctcaaatggc agcagaaact gctacaaaag cagcaatgga
    20281 acacggatta aagactgttg aagtaacagt taaaggacct ggttctggac gtgaagcagc
    20341 aattcgttca ttacaagcta caggtttaga agtgactgca attcgtgacg tgactccagt
    20401 tcctcataat ggtgcccgcc ctccaaaacg ccgtcgtgtt taatgagtgc cgctcatttt
    20461 gagttttatc agtaacgtca ttgaacaaga cacttttcgt tttgaaaggg gtaaagataa
    20521 gaatgattga gttcgaaaaa ccaagaatcg caaaaattga tgaagaaaaa gattatggca
    20581 agttcatcgt tgaacctctt gaaagagggt atgggactac tttagggaat tccctacgtc
    20641 gtattttatt atcttctttg ccaggtgctg ccatcactaa tattcaaatc gatggtgtac
    20701 tgcatgaatt ctctaccatc aaaggtgtta gagaagacgt cactcaaatc atcttgaaca
    20761 ttaaaggctt agcgctgaaa atgtatggcc aagaagaaaa aacccttgaa atcgatatta
    20821 ccggacctgc tacagtaact gctggcgata ttatcgttga tagtgatgta gaaattctta
    20881 acaaagatat gtacatctgt agtgtctctg aaggagctac gttccatgct cgcttaacag
    20941 tgaaacctgg acgtggttat gttcaagcag atgaaaataa aaaagaagat atgccaattg
    21001 gcgttcttcc agtcgattca atctacacac ctgttcgtcg tgtgaactat caagttgaga
    21061 acacacgtgt tggacaccgt gaagattttg ataaattgac gatggagatt tggacagatg
    21121 gttcaattga accgttggaa gcaatgagtt tgtctgcgaa aatcatgact gaacatttgg
    21181 atatttttgt gaacttaact gatgaagcaa aaaatgctga aatcatggtc gaaaaagaag
    21241 aaacacaaaa agaaaaaatg ttggaaatga cgatcgaaga gttagacttg tctgttcgct
    21301 cttacaattg tttgaaacgt gcaggaatca atactgtaca agaacttaca aataaatctg
    21361 agcctgaaat gatcaaagtc cgtaacttag gacgtaaatc attagaagaa gttaaagcaa
    21421 aattgcacga cttaggttta ggtttacgta aagaagatta aaacctttta cgaaggaggg
    21481 aaaccaacgt gagttatcgt aaactaggac gcacatctag ccaacgtaaa gcgatgttgc
    21541 gtgatttaac aactgattta ttaatcaacg aacgtattgt gactactgaa gctcgtgcga
    21601 aagaagttcg ctcaactgca gaaaaaatga tcactttagg taaacgcgga gatttgcatg
    21661 cacgtcgtca agctgcggct ttcgtacgta atgaagttgc cagcgtgcgt gaagaaaatg
    21721 aggacatcgt cattgaatca gctttacaaa aactgttcaa cgatattgca cctcgttacg
    21781 cagaacgtca aggcggatac acacgcattt tgaagacaga accaagacgc ggtgatggtg
    21841 caccaatggt tgtcttagaa cttgtctaaa atcacactaa taacatcact ttatagatga
    21901 ttcttttaga gtgttatgat gttggaagat atttttccga gtctagctca gcgctgctcc
    21961 tcaagcgaat atcgcttggg gagtaagcac tcatcataaa gtgttttttt ataccttcaa
    22021 ttacctgtca tgacagatat gtttgaaggc ataaaaaaac attttaagcg agaaataatt
    22081 gaaaattttg tctttttttg atagtgttag taggaacttt aggatgaaga aggagtaatc
    22141 atggagccaa ttattgaatt agaaaagata aattataaat accagccaga tgatcttcgc
    22201 cccgcattga aagatgtctc ctttacaatt gataaaggtg agtggatcgc tattattgga
    22261 cacaatggtt caggaaaatc gacacttgcc aaaacgatca atggattgct tctgccagaa
    22321 tcagggatcg tgaaagtggg aaatcaaata ttggatgaag aaaatatttg gacgatccga
    22381 cagatggttg gaatgatttt tcaaaatcca gacaatcagt ttgttggttc gacagtagaa
    22441 gatgacgttg cttttggtct tgaaaatcaa gggattccca gagaagaaat gctagtgcgt
    22501 gtgaaagatg cacttgagaa agttagaatg gctgagtttg cttcacgcga gcctgctcgt
    22561 ttatcaggag ggcaaaaaca acgtgttgcc attgccggcg tggttgcctt acgacctgat
    22621 atcattattt tagatgaagc aaccagtatg ctagatccag aaggtcgtga agaagtgatc
    22681 tctacgatca agaagatcaa agaagaaagt caattgaccg ttatatctat cactcatgat
    22741 attgatgaag cagctaatgc caatcggata ctagtgatga gacaaggcga acttgtccgt
    22801 gaaggtacac caaaagaaat tttttctgct ggtcctgaac tgatcgactt aggtctagat
    22861 ctaccatttc ctgaaaaact gaagagcgca ctgaaagaac gtggggttga tgtgcccagt
    22921 gaatatatga cagaagaaag gatggtggat tggttatgga catccgtttt gaacaagtag
    22981 acttcactta tcagccgaat acaccatttg aacaaagagc cttatttgac atcaatatga
    23041 cgatcaaaga aaacagttat actgcattag tagggcatac cggaagcggg aaatcaacct
    23101 tacttcagca tttgaatgcg cttgttaagc caacaagcgg tacagtccat attggagaac
    23161 gagatattca gccggatacg gataataaga atttaaagcc catccgaaaa aaagttggca
    23221 tcgtctttca gtttccagaa gcacagctat tcgaagaaac ggtagcaaaa gacattgctt
    23281 tcggtcctaa aaactttggt gtcagcgaag aagaagcact agtcctagca aaagaaacat
    23341 tagaacaagt tgggctggat gaaagctatt tggaacgttc gccatttgaa ctttcaggag
    23401 ggcaaatgcg tagagtagca atcgctggtg tgcttgccat gaggccggaa gtacttgtat
    23461 tggatgaacc aacggcagga cttgatcccc agggcagaaa agaaatgatg gagatgtttt
    23521 ggcgtcttca taaggaacag cagatcacta ttgtattagt tacgcattta atggatgatg
    23581 tagccaattt tgcagattat gtctatgtgt tggaaaaggg acgaatcgtt aatagcgggg
    23641 agccgcaaga ggtctttcaa aacattgaat ggctaaaaga aaaacaacta ggcgtaccta
    23701 ctgccaccga gtttgcagaa gaattaatgg ctaaagggat gaactttgct accttgcctt
    23761 tgacagctga agaattagca gacgctatcg tccattatgc tggaggaaat gcccatgatg
    23821 aataaattga tatttggtcg ttatatgcct ggagattcct tgatccatcg attggatccc
    23881 cgagctaaat tattagccag tttttatttt atcggaatca tttttttagc aaataattgg
    23941 gaaacgtacc ttttgttggc atttttcaca ttactttctg tcttcttgtc aaaagtagat
    24001 ttgaaatttt ttatccgagg cattcgccca ttgatctggc taatcctctt cactgtagct
    24061 ttgcaggtct tgtttacaag tggcggagaa acttattgga gttggggtgt tttccatatc
    24121 actgaatttg gtgtgatgaa cggcctcttt attttctgtc gattcgtgtt gatcattttt
    24181 atgtcgactc tactcacgct tactacaccg cctttggaat tatcggatgc gattgagtac
    24241 ttgcttcgtc cattgaaagc cgtacggttc ccagtccacg aaatttcatt gatgctgtcg
    24301 attgctcttc gttttgtgcc tacattgatg gacgaaacag aaaagatcat gaacgctcag
    24361 cgcgctcgcg gtgttgattt tggtgaagga aacctagttc agaaaatgaa agcagtcatt
    24421 cctttgctga ttcctttatt tgtcagcagc ttcaaccgtg cggaagatct tgcgactgct
    24481 atggaagcaa gaggctacaa aggtggggaa ggaagaacga aatatcgtgt attgcattgg
    24541 cataatagag acacgatggt tatcattgct tttgtattat taactgtgct actgatcttt
    24601 ttaagaggat aaacgttcag tgggccgcta tctattcttt tcttgctgat ctgtttgcaa
    24661 gaaaggatgc aagcagtgta tgacaagaaa tattagggtc tgtggcagac taaggtcaca
    24721 ggcctctttc ttttatctga aaagaaagaa cgaaaaaatt ttatagaaaa atcattattc
    24781 cagataacct tttaggaaca aaggagagaa aaacatggta cgttacaaag caatcattgc
    24841 gtacgacgga acaaatttta atggattcca aaaacagcca aatgggcgta ctgttcaaga
    24901 agaagtagaa aaaacattac aaaaaatggc aaatggaaaa gaaatcacgg tctttggttc
    24961 gggaaggaca gatgccggag tacatgcgat cgggcaagta atccattttg attatccaga
    25021 ggagcgtccg ttagaacgaa tgcgtttcgc gctagatacc cagtcaccag aggatattgc
    25081 tgtaagacaa gtagaaattg tttcagaaga cttccacgca agatatttgg tcaaagaaaa
    25141 gacgtatcaa tttcgagtgg atatagggaa accacgcagt ccttttcgac gccattatgc
    25201 aagttatttt ccttacccac ttgatttgga aaaaattcag cgggcgcttc ctgatttatt
    25261 agggactcac gatttcacct ctttttgtgc atcaggaagc tcgatagagg ataaaatacg
    25321 tacgatctac gaggctaaga tggaggtaaa tgaaacaaaa gacgaattgt tgtttacatt
    25381 taggggaaat ggcttcttgt ataagatgat acggatctta gtaggaacgc ttttgaaaat
    25441 tggcaatggc cgattgcctg aagatagtat cccagatatt attgcgaaaa aagatcgtaa
    25501 tgcagcagga cctacagcac accctgaagg actttatttg tatgaagtga aatatgaata
    25561 agaggttatg atagaagtgg tcagcttcaa gaaataagaa ggtatttacg aaaattactt
    25621 ctcaaaattt tgcaaaattt cggcttattt tcgaagaagc tacttctgga acaccgttta
    25681 agaaagaggt cgtgagcctg tcatttaact ctgagtcaca aagagcaatt tcaaaaaaca
    25741 gcttctcatc tttgatgaat atcgtgactt gtggacgagg cgttgataag tgaatcatct
    25801 ttttgttacc tattttttct gtaaccaaaa aacgatggaa cgttgttttg attgcccttg
    25861 gtgcggacag tctgaacagg ttccatcgtt tctttatttt ctacgtcttc ttctgtgtgt
    25921 gtttcgtggt tgttcttcta ttgctggatc aatcgtgcca taaaaggggc gattgcggtc
    25981 aaggtaccag acataaagaa taaacaatgc aatacatagg acaaaaagga ttgcacctat
    26041 cgtaaatcct tcaggcaagt aactgaaagt gacagtatgt ttacctgctg gaacttttat
    26101 catcaagaat gcgtctttga aattgctgac cttgactggt ttcccatcaa ttttagcttt
    26161 ccatcctttg tcataaggaa tagttgtcac caacatggaa tcttcagcgg tatttacagt
    26221 cccagaagct tttctgccag tggcttccat ttcgacacct ttttctttga tctgattcat
    26281 tgcggcttga taggctacaa catctagacc aacgacttta ggctccatga aacttatttc
    26341 tttcgtccca taaaaacttg cagtaaatgt cactgttgtc tcttgaggat aatagccaag
    26401 atcatagtat tgaccagaaa tgttgatttg cgtttttcgc gatgtaccat tgacagtgat
    26461 cgtcgcacta gaactttcta attgcgcaaa attggttggg aacaaactta agtaagcttg
    26521 tgtatttgca ggcacatgga cttcccaagt gagctctttt ggctggttat ctgctgtttc
    26581 tgagtaagtg acgccagtcg ttgtctttgt gatcgtcgta ttcaactgat tcttcaaagt
    26641 aggtgtatag aatgtaaaat actgttcatt tagaccagac aatgtattga tcaagtttgt
    26701 ctgactggtc aaattatctg tcactggctg ctcaacatca ttaacggaca acggtgcagt
    26761 aaatgctagt ggcaatgcat tgacattctg atacagtgta tagtcgccgc tttgaccagc
    26821 ttggcggaag ccatatttac tgaacgtgct ttcgttttta gaaatgttat atttgattcc
    26881 tgtaaaccca tccatcagca aagtattatt gttataacgg atattcaaat ttgtccctct
    26941 tgaacggaaa cctaatttat ccaggtaaga ggaagaatta cgatttctta tagaagaaaa
    27001 caaactgata ccactgtaac catagttgat cgaatcgttt gcagatactg gatccagatt
    27061 ttccaagcgg taaaacgagt cggaatcttt ttttgtttca tttacaagag ctttcaagtc
    27121 aggataagga tcagtatata aactgcggga agcataattc caatcatcaa gaatgccatg
    27181 gatcatactg ttcgtattga ccagtgcttc agcagacatg atcaataata acaatatact
    27241 cagatgattg aatgaaagtt ttttatgctg ataaaatccc acagcaaaag cataaatccc
    27301 taagaaaacc actgtcaata caaaggaagt catcgtcaca taggtgtagc ttccttcagg
    27361 tttgatgccc catgccaccg caaagagagc agctacgacc aaaatgattc ctaacaacag
    27421 cccaccatcg tcttgttcta tcttttccca tccttttcct gcaagcagga gcactaagaa
    27481 agagaacaga taggcataac ggaataaaaa catattcggt gcatgcatac catgccagaa
    27541 caaattcaat ggaacaagat aaaaacttgc gataagtatg gcgaaaagac tgccgtacaa
    27601 aaatttattt ttcaacggta ctttccgact ggcaaaataa aacagacaga ggactaatgg
    27661 tagcagacct gcgtaaacga acggaatcga tccgtatttt gtcgtgtcat aaacaccaat
    27721 catatttttc atgattagat ccagataaga agtcgcttct gttttcaacg tagtgatctg
    27781 actcagtgcc tcgccatttg accgaagatc cagcactgct ggcaatacaa tgatcattga
    27841 agcgccgcct gccagtaaag aagtgatacc ataaggaaca atcgtttttt tatattctga
    27901 ccagtttgtc aatagacggg cgataaaata taagaaagaa aatacgccaa tcataaaacc
    27961 catataaaaa ctggataaaa acaagagtaa ataactgata aataaaagtt tcggccgttt
    28021 aagatccata acacgatgaa tccccaaaat cactaatgga agataaacaa atgcatccag
    28081 ccacatgatg atctccgaat gtgcagtgat aaatgagatc aatgcgtaac tgacgctaag
    28141 tgcaacatgc ccccagcgag gaatcttgaa cgtacgtgca agaaaccaaa aagccaatcc
    28201 ggcacagccg accttaagca aagtcagaac atacagtgca tctggcatca tctggtttgg
    28261 aaaaaagaac accagtggcg tgaagatccc gcctagatag taagaaatta aagataaata
    28321 attcaatcct agagaagcat tccatgtata aaaaatactt tgctttccaa gaagaacatt
    28381 tcggaagctg gcatgaaaat tagaaaactg tgaaaaggca tcacttgcca aaatacttct
    28441 gctgcttcca ggatagattc cgatacttag ataaacaagt gctaaaatca aaaacggaat
    28501 caggaaacta gctgctgcgt agcgtccgtt ttctctaaag aatgacttta aatttttttt
    28561 catatttatt ttccaccaaa tttctatgaa gttgtattca gtttatcata tccttgtttt
    28621 tctctgctta aaaagagtct agttttcaca aaaaaataaa atttagaata aataacttca
    28681 taatttgttc gtataacaaa aataaacgca aaaaaagggt aggaatcaaa agtcccaccc
    28741 ttaaaaattt ttattaaata aaaaaccgtt cactatctga acggtccaag tatcattcaa
    28801 ttaaacgcgt tcaacttttc ctgatttcaa agcacgagtt gacacccaaa cttttttagg
    28861 ttttccgtcg accataacgc gaactttttg taagttaggt ttaacagtac gttttgttga
    28921 gttcatagcg tgtgaacggt tgtttccact ttttgtcttg cgacctgtaa agtaacaaac
    28981 ttttgccatg gtaatttcct cctttgcctt gatttggagc aatagaataa ttcagctcat
    29041 accagactaa catatcatat agaatgggaa tttgcaagta cattttcata gatacaattg
    29101 acaattgaga agaataattg taaattaaac aaggttatac ctgaaatttt gcaaggtttt
    29161 tgagtacttt gggtaactgc cttttatttc aagttgcgct atgataaaat atgatagaag
    29221 aaaaatggga gttttttacc cgttaaggag gctcattcat ggctgtaaaa attcaaacgt
    29281 cagctggaac cattgaaatt accaatgatg taattgcaac agttgttggt ggcgccgcga
    29341 cagatgtgtt cggtgttgta ggaatggcca gcaaaaatca aattaaagat aatattactg
    29401 agattttgcg taaagaaaat tactcaagag gagtagttgt ccgccaagaa gataatggta
    29461 ttgctgtaga tgtttatacg attatcagct atggtacgaa aatctctgaa gtttcccgca
    29521 acgtccaaga aaaagtgaaa tacaatctag aggcattatt aggcgtaact gccaattcag
    29581 ttaatgtctt tgtacaaggt gttcgtgtac tgccagacta ggcaggagac tggctggtaa
    29641 ctcagcagtc gatctgaagg aggattatct aggtgagtgt aacagaaata agtgcaagcc
    29701 agttccagga aatggtccag gcaggtgcga atcgtctgca agtaaatgca gaatacgtca
    29761 attcattaaa tgtattccct gtgccagatg gcgatacggg aacaaatatg aatctatcta
    29821 tgactagtgg agctaaggca gtagtagatt caacctcaga aaaagtagga gaattagcag
    29881 caatgctttc aaaaggattg ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc
    29941 aattgtttcg tggattttct aagcaaattc cagatgttgt ctcattaaat gcttctgatc
    30001 ttgctgcagc cttcactcat ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag
    30061 aaggaacgat tttgacagta gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa
    30121 gtactgatga tgtcgttgaa gtaatgacag ctgttgtaaa aggagcaaag cgtgctttag
    30181 ctaaaactcc agacttgctt ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc
    30241 aaggactgct gtttgtttat gagggctttt taagtgcatt gaatggagaa ttccaagcgg
    30301 atgaaacata tgaaccttct ccagcagaaa tggatgatat ggtcaatgca gaacatcatc
    30361 gcagtgtcca aggtcaaatg gcgacagaag atatccattt tggttactgt acagaaatca
    30421 tggtaaaaat cggagaagga cctacagtcg atagtacatt cgattacgaa gaattccgta
    30481 actatttaga tggtatagga gattctttac ttgtggtcaa tgatgacgag atcatcaaag
    30541 tccacgtgca tacagaaaac ccaggagaag tcttgaatta tggacaaaaa ttcggttcat
    30601 tagtcaaaat caaagtcgac aacatgcgct tgcagcatga gacgattttg gaacacgatg
    30661 aagaagtgaa cgagtttgcg aaaaaagaaa taccacgtat cccgtatggt atcgtagcga
    30721 tcgctgctgg taaaggcgtc caagagctgt ttgaaagttt aggcgctaat tatgttatca
    30781 gtggtggaca aacaatgaat ccaagtacgg aagacattgt taaagcgatt caagaagtaa
    30841 acgcagataa agtgattgtc ttgccaaaca ataagaacat cttcatggca gctgatcaag
    30901 cagcagaagt agcagatatc ccagtagcag ttgttccttc aagaacgatt tcccaaggat
    30961 tgacagctat gctttcattc aatgatcaag cttctttaga agaaaacaaa gaaacgatga
    31021 cagaaatgtt gtctagcgtt gtgagcggtc aagtcactca cgcgatcaga gatacctcaa
    31081 ttgacggtgt agagatcaaa gaaggagact ttttgggcat gatcgatgga aaaatcctga
    31141 tctctaaccc agatatcaca gcaacagcgt taagtacact agaacaaatg atcaatgagg
    31201 acacagagat cgtaacgatc ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat
    31261 ttgctgagaa actaacagaa aaacatcctg atttggaaat cgagatccac caaggagatc
    31321 agcctgtcta tccttatcta ttttctgctg aataatttct gtgtcagaat atctttctaa
    31381 cacagtattc attcataaaa ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc
    31441 ctttttttgt taaaggaggg aggaaaaatt tatgcgttct ttagatgatc caatcactat
    31501 gctggcagga gtcggagaaa aaagagcagc tagtcttgcc agcttgggca tccaaacgat
    31561 tgaagactta ctgacttatt atccttttcg ctacgaagat attcaggaaa gaaatctaaa
    31621 cgagatccag gatcaagaaa aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat
    31681 gaatcgattt ggttataaaa aaagccgatt gcaatttcgt atgatgcaag aacatgatgt
    31741 gttcaacgtt tcttttttta atcaacctta tctaaaagaa aaagtcattt tatcggagga
    31801 aatcgccgta tacggtaaat gggatgcaaa gcgtaaagcc ttgaacggga tgaagatttt
    31861 aggttctcaa acaatggatg acttttcgcc gatatatcac gtcaacaaat caattcgtca
    31921 aacgacatta gttgatctaa tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga
    31981 aaatctgcca aacaaccttg tggagaaata tcgactgctt gaccgagctt ctgctgtaag
    32041 aagtatgcat tttccaaaag accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt
    32101 tgaagagttc tttttatttc aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga
    32161 aacgaatggt ttggagatcc tttatgatgt ccaaaaattg aaacaattta ctcaaaagct
    32221 accttttgaa ctgacaaatg cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg
    32281 cagtccgcag catatgcagc gacttttgca gggagatgta ggtagcggaa aaacagtggt
    32341 tgccgcgatt gcgttatacg ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc
    32401 tacagaaatc ttggcacaac aacatatgga aagcttgcaa cagctgtttg atcccaatga
    32461 agtaaccatc gcattgatta cggggtcaac gaaagcaaaa gaacgacgtg agctccttga
    32521 aaaactagag caaggggaaa ttaacgtcgt gatcggcaca catgcattga tccaagatgg
    32581 agtcgaattt cagaatttag gtctagttat tacggatgag cagcaccgtt ttggcgtgaa
    32641 ccagcggaaa gtacttcgtg aaaaaggctg gcgaccagat gtcttattta tgacagcgac
    32701 tccgattcct agaacattag ctattacagc atatggtgag atggatgtat ctatcattga
    32761 tgaacttcca gctggacgta tcccgatcga aacacgctgg gtaagaacac ctcaattgga
    32821 cagtgtactg gattggacga aaaaagaact ggcaagagga catcaaatgt atgtcatctg
    32881 tccgctgatt gaagaatcag aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa
    32941 acttcgtgaa ctatttgcac caaaatatga agttggcttg ttacatggta aaatgaagaa
    33001 tcaggaaaaa gaagtaatca tggaagcctt caaagacaac cagatgcaga tattagtttc
    33061 gactactgta attgaagtag gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga
    33121 tgcggatcga tttggattgg cacagctgca ccaacttcgt ggacgtgttg gacgcggaag
    33181 tgatgcttcc tactgtatct tagttgctaa tcctaaaaat gaactaggtg tggaacggat
    33241 gaaaatcatg acagagacca ccaatggttt tgtactaagc gaaaaagatc tggaattacg
    33301 tggtcctggt gaagtatttg gcttccgtca atctggtctg cctcaatttg cgattgctga
    33361 cttggtgacg gatggaaatg ttttggaggt agccagagaa gaggctgcag ccctttggca
    33421 aataaaggat tggcagatgc ttcctgagta tcagccttta gcgcaaagcc tccaaataga
    33481 aaatcaggat aatcgttatt tcgattagca gactgtgcta tactttatac tgatgacgga
    33541 aaaaggagtg gaaacaatga aaattgccgt agatgcaatg ggcggagatc acgcacctca
    33601 agcaattgta gaaggcgtgg ctttagcgca gcaagatttt ccagaagtag aattcttact
    33661 ttacggaaaa gaagcagaaa tcaagaaata cttaacaaat gaaaaaaaca tcacgattat
    33721 ccatacagac gaaaaaatca atagtgatga tgagccagta aaagcaattc gacgaaaaaa
    33781 gactgcatca atggtccttg ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt
    33841 ttcagcaggg aatacaggcg cgctactagc agcagggttg ttcatcgtag gacgtatcaa
    33901 aaatatcgaa cgccctggct tgatgtctac cttgccagta gtagggaaag aaggtgccgg
    33961 tttcgatatg ctggatcttg gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata
    34021 cggtatttta ggttcttttt atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc
    34081 actcttaaac aacggaacag aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga
    34141 actccttcag aatgaaacaa gcttgaattt tattggaaac gtagaagctc gtgagctact
    34201 caatggtgtg gctgatgtag tggtcacaga tggatttaca ggcaacgctg ttttgaaatc
    34261 tattgaagga acagcaatga atatgatgaa tctattaaaa tctgctattc taaatgaagg
    34321 gatcaaagga aaaatgggcg ctatgctttt aaaagacggc ttacgttctt tgaaagcaga
    34381 aatggattat tccaaacatg gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa
    34441 aactcatgga gcaacaggcc ccgatgctgt tcgctatacg atccgccaaa tccacacaat
    34501 gcttgagaca gatgtagttg gacaattagt cgaacaattt gaaaaaagcg aagaatagta
    34561 tttggatatc tgaagcgatc cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc
    34621 agtaaaatta gccatggtgt aggtaattga caagtgtatg attcttggag gtgaaaaagt
    34681 tgactcgcga agaagtattt aacaaagtag cgaaaattat ttcaaatcat tttgagatag
    34741 ataccgataa agtgacggat gaattgaaca tcaaagatga tttaaaagct gattcaatta
    34801 gtattatgga attcgtttta gagcttgaag atgaattcgg tacggaaatt tcagatgaag
    34861 acgctgaaca aattgaaaca gtcggtggcg cagtagatta tatcagcagc catcttaaat
    34921 aatttcaaat aaaagcaaag aaggataaaa agctgcatgc agctttttat ccttcttttt
    34981 ttaatctttt tgacacgtaa aagtcatttt tctgataatt ctggcgataa acagaaatta
    35041 tgttgcaaag taaagcggtt ttctatataa ttattaataa ttcattacac aaagataaga
    35101 ataacctttg ttataaaacg atttattctg tgtaatgtcc ttttttatta agaaaaactt
    35161 ccatttagga agcagagagg ggtattcgat tgtccgataa ccaattatta gaagttcaga
    35221 acctacatac aggattccga ctcaaagatg actattacga tgcagtagat gacgtttcat
    35281 ttactttaga caaaaacgag attttagcaa tcgttgggga atctgggtgc gggaaaagta
    35341 ccttggctac tacgattatg ggattacttg atcctaataa cacaaaaatt acaggtgaga
    35401 ttttatataa cgatctgaat ttaatcgacc tgaacgaaac gctctataat aaaatccgcg
    35461 gaaatgatat cggaatgatt ttccaagatc cgttgtctgc attaaatcct ctcatgagaa
    35521 tcgaagacca gatcaaagaa ggactttcct atcacacaaa gatgaatgca gaacagcgtc
    35581 aagctcgtgc actagaattg ctagaacaag tagggattcc taatcctgcg agagttggac
    35641 gccaatatcc ccatgaacta tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa
    35701 tcgcctgcaa acctccaatc gtcattgcag atgaaccgac gacagcccta gatgtaacca
    35761 tccaagcaca gattcttgat ttactgaaag accttcagga agaaacaaaa acagggatca
    35821 tcttgatcac tcatgactta ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt
    35881 atggcggaca gttcgttgaa gtagcaggtg taaaagaact gtttgatcat cctaagcatc
    35941 cttatacacg ctctttactg aactctatac cacaagaagg aaatcatgat acagaactcc
    36001 atgtgatcga aggtgtcgtt ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg
    36061 caccacgtat tccatggata ccagcaagcg atcatgaaga agagcctatc cttcatgaag
    36121 tcgcaccgaa ccacttggta cgttgctcct gctataagca tttccacttt agagacgaaa
    36181 aaggagaggt gtagatgaca gaattaatca caatcaaaga cctgaaagtt cattacccta
    36241 ttcgcagtgg attcttcaat cgagtaacgg atcatgtata tgctgtagat ggtgtggatt
    36301 ttattatcga aaaaggaaag acatatggtt tagtgggaga gtctggctct ggaaaatcta
    36361 ctacgggaaa agccgttgtg ggattagaaa aggtaacagc cggacaaatc atgtatgaag
    36421 gaaaagatgt aacgaagcga agcaaccgca aaaaaatggg ttataacaag gatgtgcaga
    36481 tgatcttcca agattcaatg tccagtttga atcctaaaaa gcgagtgttg gatatcattg
    36541 ctgaacccat ccgaaatttt gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag
    36601 gactgctaga tatcgttggg atgccggaag atgcgctata taaatatcct catgaatttt
    36661 caggcggaca acgtcaacgt ctaggagtag cccgtgctgt tgctaccaat ccaaaactga
    36721 tcgtagccga tgaacctgta tctgctctgg atctatctgt tcaagcgcaa gtattgaatt
    36781 tcatgaaacg aatccagcaa gaatacggcc tcagctattt attcatttca catgatttag
    36841 gtgtagtaaa acacatgtgc gacaatatcg caattatgta caaaggtcga tttgtagaaa
    36901 tcggtacaag agaagacatt tataatgacc cgcgacatat ctatacgaaa cgtctgcttt
    36961 cagctattcc gcaaatcgat gtagaaaata gggaaagcca caaagaaaat cgacgaagag
    37021 tagaacaaga gtatatccaa aaccaaaaag aatactatga tgcgactggt cgagtctacg
    37081 atttgcgtac gatcacaact acacacaaag tggcgttgaa agatggaggt gcaagctaat
    37141 gtggaaaacg attctgcgac gtgttttatt gatgatcccg caagttatta ttttaagtgt
    37201 tctgatcttc ttattagccc aagcgatgcc gggggatcca tttaccggtt tgatcaatcc
    37261 aaatcaggat ccggcagtga tcgaacagat gcgacaagca gctggcttga atgacccatg
    37321 gtatgtccag tacttccgtt ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt
    37381 cttatacaaa cgctctgttg ctgacttgat cggcgaacgg atcatcaaca ctttatatct
    37441 atcgatcttg acagttgtcc ttacttattt gattgctgtg cctctgggga tgcttgctgg
    37501 ccggtatcaa aattcaatct tggataagat tgtcgtaatc tacaacttct ttagttttgc
    37561 tgttccttta tttatcttcg gcttgatcat gctatttgtt tttggttatc gtttaggctg
    37621 gttcccaaca agtggatcac aaacactagg tttgcaaggt ggatttatca ctcaatggat
    37681 agaccgtttg aaatatattc tgttaccatc aattacccaa gcatttttgg cgactgccgt
    37741 cacaatccaa tatctgcgaa gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac
    37801 agcccgttcc aaaggggtac cgacgaataa agtattcagt cgacatattt tccgaaatgc
    37861 agcgttgccg atggcttctc aaatggggta tgaaatcact tcgttgattg ctggttctgt
    37921 agttatcgaa aagatttttg gttatccggg agtcggaaaa ctatttattg attccatcgg
    37981 ccaacgggac tataccgtga tcacatcctt agtattgatt ttaggaatcg cgacgctagt
    38041 ggggacatta ctttcagata tcatcatgag tatcgttgac ccgcgtattc ggattcaata
    38101 aaaccaatca gaaaggagaa tggatcgatg agtgaaaaaa acaatacagc agttcaagaa
    38161 agtattcctc ctatggggat acgaatgatt gctcgagaat ttaaaaaaga taaaattgct
    38221 attttttcat taggtttgct agtggtttta ttattagtga tctttatcgg tgcgatgctg
    38281 accgatcaag acaaagtgat gtatgttagt atcttcgaca aatacgctgc accaggaaca
    38341 gtttcgacac aaggacaaaa gttcattctg ggagcagatg aaggcggacg tgatgtatta
    38401 ggacaattga tcataggtgc tagaaactct gttacgatcg gatttgcgat cacgatcctt
    38461 acttcgatca tcggggttgg attagggatc atctctggct actacggagg gatcattgac
    38521 aacatcttga tgcggatcgt tgattttatc atgattctac cgatcatgct gatcattatc
    38581 gtcttcgtat cgattatttc cagatacaat gtctggtcct ttatattcat catgagtgca
    38641 ttttattggg tagctaaagc ccgattattc cgaagcaaga cattatctga agcaagaaga
    38701 gattatgtca gtgcctcaaa aacaatggga accaatgatt ttaaaatcat gttccgcgaa
    38761 atcatgccga atctaagttc attaatcatt actaatttga cgatgaactt tgcggcaaac
    38821 atcggtatcg agacaacttt gactttctta ggtttcggct tgccggcaaa tgtacctagt
    38881 ttaggtacat tgatcggtta tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc
    38941 tggttacccg catcaatcct tattttagtt ttgatgttga gtatcaatta tgttggacaa
    39001 gcattcaagc gttctgcaga tgcgcgccaa cggttaggct agtatagaag cgaaggggga
    39061 aataggaatg aagaaaacga tttttggatt tgcagcgctg atgtctgctg tcgttcttgc
    39121 agcatgcggg ggcggaggta cagatacctc tggaaacaac tctggaggca acggcaataa
    39181 caaagaggaa ttaacttttc caattgcaac aaaaaataat gatgatgcaa tcgaagacgg
    39241 cgaattagaa gctgcggtcg caacggacag tcagtttaaa ggattgttcc agtgggagtt
    39301 ttaccaagat tcatatgatg cagcttttat ggctccttct catgaaccgc tatttgcaaa
    39361 cgatgacgat ttcagaatca cagacgacgg agctgcaacg cttgatctag atgaagatac
    39421 gaaaaaagcg acaatcaaag taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac
    39481 ggcggacgat gtgattttcc cttacgaaat cattgggaat aaagattaca ctggtatccg
    39541 ttatgacgac actttccgta acatcgtagg tatggaagaa tatcatgatg gaagtgccga
    39601 cacaatctcc ggaatcaaaa aaatagacga caaaacagtt gaaatcgaat ataaagaagt
    39661 aaacccaagc atgcttcaat cgggtggtgg tatctggtca tatgcagcac caaaacatac
    39721 gttagaaggt gtagcaatca aagatatgga atcaagcgat caagtacgta aaaatccagt
    39781 gacttttggc ccttattaca tgagtaatat cgttgcagga gaatcagtag aatacttgcc
    39841 aaacgagcac tactggaatg gtacgcctaa attgaaaaag atcacgatga aatctgtacc
    39901 gatggcaagt gcaactgaag cattgaactc taaattatat gatatgattt tccaaatgcc
    39961 aacagatact tacgatacct ataaagaaat tgctggctat acaaacttag gccgtgaaca
    40021 aacttcttat acttatctag gattcaagtt aggtaaatgg aatgcagata caaagagtgt
    40081 ggaatacaat ccagattcaa aaatggctga taaatcatta cgtcaagcaa tgggctatgc
    40141 attagataat aatgcagtag gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc
    40201 attgattcct ccagtattcc agtcatacca tgatgatgag atgaaaggat tcacacaaga
    40261 tctagacaaa gcgaaaaaac tattagatga tgctggctac aaagatgtgg atgacgatgg
    40321 tttaagagaa gacaaagatg gaaataaact aacaatcaac tttgcttcga tgtccggtgg
    40381 ggaaacagcg caaccattgg cagattacta tatccaacaa tggaaagaaa ttggtttgga
    40441 tgtccaatac acaacaggtc gtctgatcga attcaattct ttctatgata aattagaaaa
    40501 cgatgatcct gaaattgatg tttaccaagc tgcttggaat acaggaactg atccaaatcc
    40561 aagtggacta tggggaccaa atgctgcgtt caactacact cgttatgaat cagaagaaaa
    40621 tacaaaattg atcaacgata tcagttcaag caaagcattt gatgaagagt accaaaaaga
    40681 agcatatcaa aaatggcaac aatatgcatt tgaagaagca tttgcgattc caacgttgtt
    40741 ccgtaatgaa gtattgccag tcaacgaccg tgtcaaagac tgggattggt cttatgatgt
    40801 accaaaccca tgggcaaatg tttctgttac agcagattca cgttcataat cactaaaaat
    40861 gaccgaaaaa gggcgatgtc ctttttcggt tttttgatat ttttctgttt atttctctaa
    40921 tattcaggtc aaggcgctga tttcatgact tctccaataa acggtgttca aagtccagtt
    40981 tctcggtatt aagtcaaatt tatgcaaaaa tatggaaagc cattttcaca aaattttttc
    41041 ttcatactcg aaactaaacg aatttttcac aacttctcgt caatcactag gattattaaa
    41101 gctttactta ccttttgacc gaaccatttc aaatttgaca aaaaaccagt ataataagga
    41161 agtatcgaaa aaatatccat aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa
    41221 ctaaaagaaa actataacat cgtttttcac gatctaaatt tgcttgaaca agcttttacc
    41281 cattcatcct atgtgaatga gcatcgcaat ctgcaattat cggataatga gcgacttgaa
    41341 tttttaggag atgccgtttt agaactgatg gtttctcagt atttattccg tttatatcct
    41401 catttgccag aaggaaaatt gacaaaaaca cgagctgcga tcgttcgcga agacagcttg
    41461 tcgaaatttg ccaaagaatg tcactttgat caatatgttt tgttgggcaa gggagaagag
    41521 aattcaggag gacgtacgcg accagcattg ctttgcgacc tattcgaagc ttttttaggc
    41581 gcgttatatc ttgaccaggg attcgacacg acccatgcat tcatcgaaaa agtgattttt
    41641 cctaaagtca aagcaggtgc tttttcacat gagatggatc ataaaacaaa actacaagaa
    41701 gtcttgcaaa aatcaggtga tgtatcaatc gaataccgat tgatcaatga agaaggtcca
    41761 gctcatgaac gagtattttg gatcgaagtt tatgtagatg atcaattgat tggcactgga
    41821 caagggaaat cgaaaaaatt agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg
    41881 taaaagtaag tgagggaaag ctttgtattt gaaacgaatt gaaatagccg gttttaaatc
    41941 atttgcagac aagacagtca ttgattttga aaatagcgtc acagcagtgg ttggaccaaa
    42001 tggcagcgga aaaagcaata ttacagaggc tatccgctgg gtattaggag aacaatctgc
    42061 taaaagtctg cgaggcggaa aaatgccgga tatcatcttt gccggttccg atacccgtaa
    42121 gcagctgaat attgcagaag tcacagtgat tttagacaat agtgatcatt atctgccatt
    42181 ggagtacaat gagatcagtg taacccgccg ttatcgacgg actggggaaa gcgagttttt
    42241 catcaataaa caaagctgca gattaaaaga tatccaagaa ttgttcttag attctggatt
    42301 aggaaaagaa tcgttctcaa tcatttctca aggaaaagta gaagcgattt tcagtagtaa
    42361 accggaagac cgtcgtggga tctttgaaga agcagctggt gtcttgaaat acaagcagcg
    42421 gaaaaagaaa gcagaacaga agctttttga aacagaagac aacctcagcc gcgtccaaga
    42481 catcatccac gaattggaag aacagttaac tcctttggcc gcccagagtg aggcagcaaa
    42541 ggagttttta cggctaaaag aaacactgac tcaaaccgat gtctctttga tggttgctga
    42601 aatcaagaca gcaaaaaaag attgggacaa caaacaagca cagcttgcga aattcaatct
    42661 agaattaggc aaactatctg agtcgatcca agaacaagaa tccattttgg cgaagcagcg
    42721 taaagaaaat gcgcaagccg atcgtctgat cgaaaaaaat cagcaagtat tattagatct
    42781 ttcggaaaaa ctgaagcaga cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca
    42841 tacacaaaaa agctcgcaag aatatcaaac ttcattagca gaagcacaaa aaaaggttaa
    42901 acattttgaa aagcttcaag aaagcttgat gaaagcagca gcagaaaaag aaacagagat
    42961 ccaaaaagct gaagcaaatc tcataaaaac acagcaagaa ttagaaaaat accaaaaatc
    43021 aacgaaagaa ttattggcag aattaagaga tcaatatgtt gatttgatgc aagaacaagc
    43081 agctgtagga aacgaactga agtatctaga acgtcaatat atacaagaaa cagcaaaaag
    43141 caagcagacg ttagccaagc aatcggaagt agaagcatca gtagaccgat tgatcttaca
    43201 aaaagaagaa ttgacacaaa agcaggcgca gctaaaatca tctttaactg aaacaaaaga
    43261 gaagttagaa atgatccaac aaaacgggaa aaagttccaa gaagcattag caaaagaaca
    43321 gcctaaaatg tatcaattaa tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct
    43381 tcaagaaatc caagaaaact attttggttt ttaccaaggg gttcgattgg tcttgcagca
    43441 taaacagcag ctttcgggta ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga
    43501 tttcacgtta gctatcgaaa cagctttagg tggggcagcc cagcatgtca tcgttgaaaa
    43561 tgaaaaagat gctcggcaag ccatcacgta tttgaaacag caaagaggag gaagagcaac
    43621 attccttcca ctgacgacaa tcaaaccaag acaattaccg gctcatatat tgacacaagc
    43681 agcagctgta gaagggttta tagggattgc cagtgaacaa gtcagttatc ccgatcaaat
    43741 ccaaactgtg gttcaaaacc tgctaggaac gatcctttta gccaaagact taactagtgc
    43801 caatgcaatc gcgcaaacga tccgctatca atatcgagtg gtttccttag aaggtgatgt
    43861 gatgaatgcc ggaggatcca tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt
    43921 gtttgtacaa aatcaagaat tgaaacagtt gactagtgaa tttgaagaag cagataaaca
    43981 actccaagca caagaaaaaa aagttcagga gctgcaacaa gaaacagctc gtttagccga
    44041 agaacaagaa gttttgcgta cacgaggcga acaattacgt tttgaagaac aagaagcgac
    44101 aaatcagcta caaaacatca taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc
    44161 aacttttgag acacgtgaac tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga
    44221 attgaaagac aaacaaacag atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa
    44281 atcgttaagt caagaaagcg accagatgga agccagaaga gcacaagtac aaagtcaaaa
    44341 agcacaagaa caagcagatc ttgctgtctt gaaagagcag tttaatcatc tgcagatcca
    44401 gctccgcggt gcccgagtcc aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa
    44461 gcagttggcg acattgacag cagacttttc tgatcatgaa gtcacagaag aaagtttgga
    44521 aaaacaaatt aacgaattat ctgctcagcg agaaacatta aaagccgagt tggcaaaagc
    44581 caaagagcag cgagatagaa ggcaaaagga gatcgataag cttgaagcag tcttggcaga
    44641 gcgtaatcgt gagcaaaaag cacgactgtc ggaacaatcc aaattagaag tccaaaaaga
    44701 ccgagctgaa atgattttag ataatcattt gacctatctg cagtcagaat atcagctgac
    44761 atttgagaaa gcttcccaag actatcaaga aacaaccgat atcgaagaca gtagaacaaa
    44821 ggtttcatcc ttaaaagaac agattgaaaa actgggacca gtaaacttaa attcaatcga
    44881 acaatacgaa caagtcagtg aaagacatac attcttagca acacagcgag atgatctgtt
    44941 agcagcgaaa aaccaattgt ttgaaacgat ggatgagatg gatgatgaag tgcggacaag
    45001 attcaaagaa gtatttgaag ctatccgtca agaattcaaa attgtctttc caaatatgtt
    45061 tggcggcggt aaagctgaat tagtactgac ggaaccaact gatttgctga aaacaggtat
    45121 tgagattgaa gtacaacctc ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg
    45181 agaacgagca cttacagcca tcgcgttgct cttttccatt atccgtgtct gtcctgttcc
    45241 gttttgtatc ttagatgagg tagaagcagc gttagatgaa gccaacgtga aacgttttgg
    45301 tcgttacttg agcgatttcc aagatgacac acaatttatc gtagtcacac accgcaaagg
    45361 aacgatggtc gcagcagatg tactgtacgg agtgacgatg caggaatccg gtgtatcaaa
    45421 aatcgtttct gtacggatgg aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt
    45481 gtaggaacga aaatgatcaa attagtagca atcgatttgg acggtacatt attaaatgaa
    45541 caaaagctga tttcagatga gaataaacaa gcattagcac aagcaaaaca gcaaggggtc
    45601 aagatcgttc tatgtacagg acgcccctta gctgcgatgg cgcattatct gcaagaatta
    45661 ggactggtag atgaaggtga ctacagcatc actttcaacg gcggtttggt acaaaaaaat
    45721 gatactggtg aaatcatgga aaagaaagtg atggaagtat cagatatcca acgcttatac
    45781 aaactggctc agcaattgga tctgccacta gatgttttgt ctgacaatgt ggttttacag
    45841 ctgcctagtg ccccaaggaa gcaatccttg tacaatgtgt tgaataagct gctgcaattc
    45901 caaccagcgg atataagcga tattacagat gaatttgtgc ttaataaggc agtaatcgct
    45961 tatgaccaag aagaattaga tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg
    46021 tatgagatca tcaaaacaag aagtatgctt ttggaattta tgccaaaagg tgttacaaaa
    46081 gcttatggta tttctttatt ggcaaaagat cttggtttga aacaagaaga aatcatggcg
    46141 atcggtgatg aggaaaatga tttaccgatg atccaatatg ctggactagg cgtagcgatg
    46201 gagaatgctg tgcctttcgt caaagaagca gcagatttcg tgacagccag caatgaagaa
    46261 aatggcgtag ccaaagtgat ccaaaaattt gtattagagt agggggagtc aaatgggatt
    46321 ttttgataaa atcaagcgtg cttttactgg cgaagagaaa acagaagaag ttgaagtaca
    46381 ggagaagtac gacaagggtt tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga
    46441 gttgtttgcc aattttcgaa cagtcgatga agactttttt gaagaattag aagaaacact
    46501 tatcggtgca gatgtaggtt ttgaaacagc gatacgaatt accgaagcat tacgtcaaga
    46561 agtgaaactc agaaatgcga aaaaatcggc agaagtccaa aatgcgatca tcgagaaact
    46621 tgtggatctc tatgaagcgg aaggaatcaa tgaagtaaat gaactaaata tccaagaaga
    46681 cggactaaca gttattttgt ttgtcggtgt taatggtgta gggaaaacaa caagtattgg
    46741 taaacttgcc catcagttca aaaacgaagg taaaaaagta ttgatggcag cagcagatac
    46801 cttccgcgct ggagcaatcg accagttagt tgtctggggc gaacgcgctg gtgttgaagt
    46861 tgttcgtggc aatgcaggag gcgatccagc agctgtcgta ttcgatgctt tggaaagagc
    46921 aaagacagag caggcagatg ttttactagt tgatactgca ggccgactgc aaaataaagt
    46981 gaacttgatg aacgaattag aaaaaataaa acgagtaatc cagcgggaat taccagaagc
    47041 accccaagaa acacttcttg tattagatgc aaccactggt caaaacgcga tggttcaagc
    47101 aaaacaattc aaagaaacaa cagatgtgac cggtcttgtt ttgacaaaat tagatggtac
    47161 agcaaagggc ggtatcgtac ttgctatccg taatgaattg catttaccag tgaaattggt
    47221 cggtcttggt gaaggaatcg atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg
    47281 attgttcaaa ggattactaa aagaagaata acccatgtct aaaaagcagg agctgtgaca
    47341 aaagttgcag ctccttgttt gaatgattgt ttttaacata gctgtgtttt tgatgccttc
    47401 atttttatac ttatttgtaa gcggttctca aacaatttcg ttctttttct tagacttttt
    47461 gattataatt agattcatat gaattggagg tcacttaatg atgaatttta agcaattatt
    47521 attgcatgtc aatgcgcgcc cttttatcga ccaagctcga tttggtatag aacgggaagg
    47581 acagcgggtt gatcttgcag gaaatctagc aaaaaccgat catccagcaa tctttggcga
    47641 tcgatcctat cacccctata tccaaacaga ttttagcgaa acacaaacag agatgatcac
    47701 ccctgttacc gattctattc ccgaattatt tcagtatctc gctgctgttt atgatgtgac
    47761 tgctcgttct ataccgaaag aagagatgat ctggccatta agtatgccac ctgccttacc
    47821 ggaaaaagac gaagagatca ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg
    47881 acgttattta gcaaaagaat acgggaagcg aaaacagatg gtaagcggta ttcatttcaa
    47941 ttttgaattt ggcgatgagt tgctaagaac attgttcagc catcaggaag aatttcaaga
    48001 tttttccgaa ttcaaaacag aactttattt gaaaacagcg agaaacttta tgcgctatcg
    48061 ctggatgatc acttatttat tcggtgcttc accaatgagt gagaagaact actttttaga
    48121 tgaatcacat ccgcaagaac ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa
    48181 tcatccaaat gtgaaagttt cctatgcttc tatgaaacag tatttagcag atatcgagcg
    48241 aatgatcgaa gaagggaaac tttcggagga gaaagaattt tatacaccgc ttcgtttccg
    48301 aggcggaaag aaagtcgcag atttagcaac aacaggtgtt cgttatattg aattgcggaa
    48361 tatcgatttg aatccttatg caagattggg tatcaatcca gagcaagttc ggttcttaca
    48421 attattcctg atgtacatgt tatggacaga agaaaaagaa gactgtgacc aatgggtagc
    48481 agaaggtacg actcgaaata acaaagtagc actagaacaa ccatcagatc aaacagaatt
    48541 tcatcaagaa ggtagagaaa ttcttgaagg aatgaagcaa atgctggttg aattggattg
    48601 gttggattct ctttatttag tagaggaagc attgactcaa atggatcatc ctgaacaaac
    48661 gttagcagcg aaactctatc aagaagcaca gctatcgagt cagcaagaag ttgctgtggc
    48721 attgggacat caatattata aagaaagcca tgaacgtccc tatcagttgg ccggttttcg
    48781 cgaaatggaa ctttctactc agatatttat gttcgatgcc atccaaaaag gtgtccaagt
    48841 caaagtatta gatgagtcgg atcaattttt gcgtctgcaa ttccaagacc atgtagaata
    48901 tgtgaaaaat gcaaacatga caagtaagga cagctatatc gtcccactta tcatggaaaa
    48961 caaaacagta acgaaaaaag tcttaaaaga agctgggttc cgggtaccag gaggcgcaga
    49021 attttcatcc atggaagaag cggtaaaagc ttatccgaga tttgccgagc aggcatttgt
    49081 gatcaaacct aaatcaacca attacgggtt aggtatcacg attttcaagg aaggagctag
    49141 tctggaagat tatcaagcag gtttagccat tgcttttcgt gaagacagtt cggttttagt
    49201 agaagaattt atgccgggaa cggaatatcg tttctttgtg atcgacggag aagtccaagc
    49261 catcatgttg cgagtccctg ctaatgttat tggtgacagt atccgaacag tgaaagaact
    49321 tgttgaagaa aaaaatagtg accctttgcg tggaacgaat catcgtgcac ctttagaatt
    49381 gatccaatta ggtgaattag aacaattgat gttgaaagaa caagggttga cgatcgaatc
    49441 agttccccaa gccaatcaaa ttgtttatct aagggagaac tcaaatatca gtacaggtgg
    49501 tgattcgatc gatatgactg atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc
    49561 ggtagaagca ctaggagcta agattagtgg tatcgatttg attataccag ataaagaaat
    49621 cgatcctaca actgataaaa aagcatatgg gatcatcgaa gcaaatttca atccagccat
    49681 gcatatgcat gtttatcctt ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa
    49741 attgttatat cctgaagtat tttaaaagaa aaagcttttg acagattgtc ctatttgatg
    49801 tcaatctgat caaaagcttt ttttgcatgt aaaaatttat gtgttttttc gttttaaaat
    49861 aaacgatccc agaagctttt tttctttttt ggtttttctt tttcagctgg cgaagagttt
    49921 tcttctgggt attttttttc gatatcaatc acaggttcat ttactgcttc ttttgctgtt
    49981 aagagcaatc cgaattcctc aggatttgca gtgacgtaat cgttgactac agtgaaacgg
    50041 ctattgtttt tcgttgctag ctggatatat tggttttgga cagaaagggg tagagcccca
    50101 ttcaagagta tggaagcatc tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt
    50161 tttggttgga tcatttcagc aacagtcata ctaagatagc agcgttccct gaatgtccct
    50221 aaatatttat gctgttcttc agggttcact aaaggtgtac cataaagtcc cttatccaaa
    50281 tggcttttta catcatcttg tgccataaaa aataccctcc ttcttctctt tgtctttctt
    50341 acgattatag catattccca ataataccta aaacatatga aaaagcggtt gcttttgttc
    50401 aacgattcac ttaaaataag aatgaaaatc attctcaatt agaaaggtgg attggatgcg
    50461 ctacggacga ctagtagcat tattagttat tttaagtagt atttcattgt tcatcggagt
    50521 atcgaatgta caattgtcag aactgctcca gttagatggg caaagcttac aaatcttgct
    50581 agtgactcgt ttgccacgaa cgatttgttt gatccttgtg ggagcgacca gtagtatttg
    50641 tgggttgatc atgcaacatt tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac
    50701 gatggatagt gcgcgtttag gtattttagt ggctatgatt ttcctacctg gtgcatcctt
    50761 gattgtccga tccttgacag cattttgctt tgcttttgca ggaacattgc tttttttatc
    50821 ccttacgcga ttgttcctcc agaaaaatca attgatgctt ccgttgattg gagtcatgtt
    50881 agggaatatc attggttcag ttgctacttt ttttgcttat caattccagt tggtacaaaa
    50941 tatgacttca tggcttcaag ggaattttgc gactgtgata cgaggaaatt atgagttatt
    51001 gtatgctgtt gttccattgt tgctcttggt ttggctattt gcttaccgat ttacgatcat
    51061 tggtctgggc gaatcgtttg cagtaaatct gggaatagat taccagaaga tgcagttttt
    51121 aggcattggc ttagtatcat tggctagtgc agtcatgttg atcatggtag gaagcattcc
    51181 ttttatcgga gtgatcattc cgaatcttgt ctctagaata tatggagatc aagtgcacaa
    51241 aacaattggc gtaactgctt tagcaggtag tttgttctta gtattttgcg atcttgtcgc
    51301 tcgcgtgttg atttttcctt atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg
    51361 ggctatcttc ctttatcttc tgataagggg acgacgatat gcttaaaaaa aagccatcta
    51421 tttttattgg tatgcttgtt cttgttttat ttgttacagg aatgtacttg acgatccata
    51481 catatggaaa ctggcatttt gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc
    51541 ttgtctcgct agctgtcagc agtgccacaa tcagctttca gacaattacg cataaccagt
    51601 ttttgactcc ttcagtattg ggacttgagt cgttatatgt ccttgtccaa acggtccttt
    51661 tcttctttat cggaggagtg acgatgcttc agcagacagg tacagttttt ttcttattga
    51721 acgttgggct gatggtcggg ctgagtctat tgttattttt ctttcttttg aaaaaaatga
    51781 gagcgaatct ttttttatta ctgatgtcag ggatgatttt aggtacgctt tttggtagtg
    51841 tcagtacctt tttacaagtc atcatggatc cgaatgaata tgatttgctt caaggcagat
    51901 tatttgcaag ctttggcaat atccagagtc agtatctttt gcctgcttct ttgatcatta
    51961 tcggctgctg gtacctgtta tttcgatatc gacatgtgct agacgttttc catctcggaa
    52021 atgaacaagc agtaaacctc gggatagaca cagatcgttt tgaatttttg attttatgtt
    52081 gtgtcagtct tttgacaggg acatcaacgg ctcttgtggg tccagttact tttttagggt
    52141 ttattgtcgc aaatatcagt tatcgtgtct tttctactta tcgtcatggt cagctattta
    52201 tcggaagctt tctggtagct atgctgtttc tgacaggagg acagctcgca gtagagcaga
    52261 ttttcggctg gaatacaaca gtgagtgtcg tcgttgaatt tgtcggagga atttattttg
    52321 tcacaaaatt gattcgcgaa aggaagagta tcctatgatt gatttacaaa aggtcaataa
    52381 actgtaccat ggaaaatcag tggttaaaga tgtacagtta acgattcctg aaaagaaatt
    52441 gactgctttt atcggtccaa atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg
    52501 tttgatacca aaagatacag gtgaaatcta tttagaccat aacgaagtaa aggcttggaa
    52561 atccaatgaa ttagccaaaa aattatcgat cctacgacaa tcgaatgaaa taaatgtcca
    52621 aatcaccgtg aaagaattag tagaatttgg acgatttcct tatacgaaag gaaaattgac
    52681 gacaaaagac gaggaaatcg ttcaggaatc actggaacac cttgggttag aagaaatagc
    52741 ggatcaatcg attgacactc tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt
    52801 gctagcgcaa gacacggatt atattttact ggatgaacct ttgaacaatc tagatatgaa
    52861 ttttgcggtt caaatcatgc agattttaaa aaatttagta caagaaatcg ggaaaacaat
    52921 tgttattgtt cttcatgata tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat
    52981 gaaagatgga cagttattta cgcaaggaac gacccaagaa atgataaaaa aagatgtatt
    53041 ggatgaatta tacgaaatgg acatacggat ttgtgagatt gaaggccgca gattctgtct
    53101 ttatttctaa aactaacatt aggagagaag agatgaaaaa attagtagta ggtatcttga
    53161 ttctagcatc atttggttta gcagcatgtg gaaatagcaa caacaccagt caggcagaca
    53221 caaaaaaaag cagcacacaa actgaaacta cattgacgat aacagatagt aatggagacc
    53281 aaatcgaggt gccaaataat ccagaaaaag tcgtcgtatt cgacaatggt tctttagata
    53341 cgatggatgc tcttggtgtt ggagataagg tagttggagc agctacaagc agccttcctg
    53401 agtatctttc atcctataaa aaagtagaat cagcaggtgg aataaaagaa ccagacttag
    53461 aaaaaattaa tcagcttcag ccagatctaa tcatcatttc tggccgacaa agagattttc
    53521 aaaaagatct aagtcaaatt gctccgacca ttttcctttc tttagatgcg aaaaatccat
    53581 gggaatcttt ccagcaaaat gtcactgctt taggggagat ctttggtaag caagaagaag
    53641 ctaaaactca attagaggaa ttatctagtg caatcgatca gacgaaaaag aaagcagaag
    53701 ctactgacaa aaaagcacta gtcacacttg tgaatgaagg gcaattatca gcctacggat
    53761 ctggttctag attcggtttc atccatgatt tatttggctt tgaacaagca gatgatcaaa
    53821 tcgaagcatc cactcacggt caaagtgttt cttatgaata tgtgctggaa aaaaatccgg
    53881 atatcttatt tgtagtagac agaacaaaag ctattggtgg agacgacagc aaagatgata
    53941 tttctgccaa tgaactggta gcacaaacga atgctggtaa aaatcagcag atcatctccc
    54001 ttgaaccaga tgtctggtat ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg
    54061 aagatgtgaa tcaagcattt aaatagcata aataacagag gattaaactc tcatactatg
    54121 taacaataat gtttcttaca ttcttaaata gcaagagcct atcctcaaag aagttatcaa
    54181 aaaccatccg taaaatcgta ttgatgattt tacggatggt ttttatttat ttgagaaatc
    54241 ttttttcaac gtgaattcat tatctacatc atacgggttg attctagaat ggggagtggc
    54301 aaaaaatagt gtgatccatt ttttcagcat caagatcgcc tcctttgatt tgaatcaaag
    54361 gtacaaagcg aaacttagat aaaacttaaa tttagatatt tttattttgt accgatctct
    54421 tctttaaacg atgttccatc tgctgcttct cggcaataag tccactagac tagaaaatat
    54481 gagaagctat tttctgtcca gcgttcttat tactcaaagc aaatcgcagt tgtcacaatc
    54541 tcttctaaac gatgttccat ctgctgcttc tcggcaataa gcccactaga ctagaaaata
    54601 tgagaagcta ttttctgtcc agcgttctta ttactcaaag caaatcgcag ttgtcacaat
    54661 ctcttctaaa caatgttcaa tcagctgacc ttcggtatta gctcaaagca ctgatttcac
    54721 aacctctatt taggcatgtg tctcagcaag cggttgatag ttgatgatct gcatttttcg
    54781 ataaaaatcg gcgggaagct tactccaccg ttttaataat tgatagaaat aactctcttc
    54841 tgctttgatt ttatactcgc ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa
    54901 ttttttataa atatccaatg ctttggtttt atcttcattg acaaagagtg tttttacttc
    54961 aatataagaa ccctcgatat tttgtgtttc ttcgataaaa tagatgtttt ttatatattc
    55021 cttcatagtg attcctccaa agaagtcttt tatttgataa gtttactcta ccgaagagtt
    55081 gttaataatc cgtgaacaaa aagtaattct ttttccaata gttgttaaag gttttttatt
    55141 ttttatagta ttttttgtta tttaagaaag gaataaggtt aaacaaataa caggttgctt
    55201 tttgggtctt tttccgttca agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg
    55261 ataagagaaa tcataataaa cgaatgactt actttccaat aaattgagaa cagtcagaac
    55321 cagacaaatt agttgcatct gatgaataaa gtgattattc tatgacatga ggtgatacag
    55381 atgaaattag aagtgacaaa agaagcacaa gaagtattga agaataaatt agaagcagac
    55441 gatcaacttt tattagatat cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt
    55501 tgccaattgg atacggcatt tcgattgatc attgtcaaaa aagatacaca aacagatcta
    55561 agtctttatt ctgtagtggc tgatacacca gttggaccaa tcaaaatcaa agacagtgca
    55621 atactttaca tggatgatcc atccacactt gctttagaac caacttataa tagtttacaa
    55681 ttaaaaggac caagcggctt gagaaaaggc aacttgcaag ttgttcgaaa agactagagg
    55741 gataaaatgg gaaaattggc gatcatcagc gacctacatg tggacatcaa taaattcggc
    55801 gaatcagagc tgatgcagct ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat
    55861 ctagccggag atacggctaa taaagtagac cgttgcctag ctgttgtcga atttttcgtc
    55921 aataaaggat tatctacgac atttcatttc ggcaatcacg agttggcaga tgtgcccaat
    55981 gaacagatga tggaccattt tccagaccca cattttttaa atgaacggta tattgcttta
    56041 aatgagcaga ccgttctttt agggatgaat ggctggtacg actatcagtt ttccgaattg
    56101 aaagattacg aggcaatcgt acgaatgaag cgtttgtatt ggtatgatcg gttcatccag
    56161 cgtgggaaaa cagatctcga ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta
    56221 gaccagctgg aagcaaaaaa acttgaggtg attttatcca ctcatttcgt tcctaaacgg
    56281 gcatttatca tgtatcaatc tgctccttat gagcgttgga acaaattaaa tgcattttta
    56341 ggatcagaat cattcggaga attacttgac cgttattcaa atatcaaaca agtagttttt
    56401 ggccatacgc atcgtcgctt tgaagataaa tccatcggtc acacgattta cagctgcaga
    56461 ccttttggtt attattatga atggcagctg acccgagatt ttgtcttgaa agaacagttg
    56521 ctagacagct atgatcctat gaaattacgt gtcctcttgc gtgcccatca cccagctttt
    56581 caggcctatc aaacacaaca tttgcaagag gaatttgaac aagcgatgac aatcgttccg
    56641 tattgagaca gcattagtaa tgtgtaaaag aaaatacctt gtaaaacata aggataagta
    56701 agagcagtag atccatttat cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa
    56761 tgtttatttg atcggatgat ttgtaactcg cagagtacta gatgcaagcg tgtattcttt
    56821 ttttgaacga taatcacaaa aaaaaatata atatacattt tttatttaat tataattaat
    56881 attgattgaa gtctaggcag tcaagtcaca ttttgataga taggaggggg acttacgaat
    56941 tattttaaag gctatgacag ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa
    57001 actagaaatc aaatcgggct gataatcatt tataactaat cgatacatag gaccaaatat
    57061 aggtctatgt tcttttattt cataagtatc gtaaaacaga attttgctat ggattaatcc
    57121 aatcgactga tatgtttagt aaataaagaa agaggaatgt caatgatgaa aaaagaaatc
    57181 gtattaacag cagcaatgat gttattcagc atggtagcaa gtacgacttt tgtttctgca
    57241 actgaagtat acccaaagga atataacaca gaaggaacga ttacatttga agcaggagat
    57301 gagggtgtaa ctcctcctgt tgatccagag aatcctgatc ccaataaacc tgtcgatcca
    57361 tcagatcctc caagccctgg aacaggaggg gcattatcga ttgattatgg atcaaaattc
    57421 aaatttggga ctcaaaaaat ttctactgcg gataaaacgt attatgcagc tgctgatgtg
    57481 atgaacgatg ggtctagaaa accgacatat gtccaagtga cagataggag aagtacctta
    57541 tctgggtgga aattaagtgt ctctcaacca gaacagttta aaactgccag tggggatgaa
    57601 ctagttggag cacagctgaa atttacgaaa gggcaggctg tttctttggt tgatccaaca
    57661 tatacgccgc aaacggtgaa ttctgaatta acgttgacac cgggaggaaa caatacgtta
    57721 gcaattaatg ctaaatcagg aacaggtgtg gggacttggg tctatcgatt tggtgcaaat
    57781 gaaaatgaaa atcaagatgc ggtacagctt tcggtacccg gtaaatctgt caagttagcg
    57841 caacaatatt ccactaaatt agtttggaca ttagaagata cacctaacaa ctagtttact
    57901 gaaaagaact gttaaaaata aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa
    57961 attgtcaaag gctaggctaa atttgtttgg atacgaatag ttcatctagg aatttaacga
    58021 tcaggaggaa aagatatatt gaaaaagagg aggatcgtgc tcattttaag cagtctctta
    58081 gtgactaata tctttccgat catagggtac tctttggaat tgaatcagtt ggagcatgga
    58141 aatagaagag acgaagaaag caaactcact tcgacattcg acagtttaat agaatccaac
    58201 cagacacaag aaagcagtga ggatttaagt atttcgagta gtggagagac cactgacaac
    58261 gtagaagctg agggttcgga caaacaagga ctagaagatg caccaatttc tgcggttgag
    58321 ctgcctgacg atcccaatat tatttctatc gataaaattt ttcaaacacc tatcggtact
    58381 agcacgtcca tattggaaaa tgggaagtta ctgcagttga acccagcaga aaggtctcaa
    58441 agaggagcta tttggtcaaa taagaagatt agtttactct cggattttac atttaaatct
    58501 tatttatact taggaaatca acgagataga gcgggagatg gcatgacctt tacattgact
    58561 ggcgatccta gaatggctag taatcccagt caagttattg gatcgccagg tatgggaatt
    58621 ggctcatatt ctactcgttc tggccaacct tacattgcga atgcgctctc gattgagttt
    58681 gatacgtata aaaatagtgg ttcttctgat cgaatggatc gagagataac tgctgataat
    58741 agagggcatg gacatgtcgc ttttgtcacg cctaaaccaa ataataataa ttattctgga
    58801 gagcatactg gcgtgacggt agctcctaca tttctttcta atggcacatg gcgcttgtta
    58861 ataattaaat gggacgcgga gcaaagaagt cttacttatg atttggaagg tgtcggtcac
    58921 tcttctcgga ttatacctga tctcattagg cagtttggtt ctacagaagt aaattggggg
    58981 tttacttctt caacaggtac tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca
    59041 tcgaatgtca catcaacagc tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct
    59101 gaagctggag gaaacgataa gataactatc agaaatacat tgaaggtcga gggggatttt
    59161 cttgaatata agaaaatgca gactagtatc gacctcccac aagaattaac tattcccgag
    59221 catatcttga tcaatggaaa tcaaattgat gccaaagata tcttgataac cggaaatcga
    59281 gtcacgctaa atctgacaga ttattttatt gctggagata cgttaataat cgaattggag
    59341 acaactttgc aggaagtaat tcctgaaaaa gtactcacta tgcattttga ataccttgaa
    59401 aacgggaatt tgattgagca atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag
    59461 atagatatcc atgtttatta taaagataaa gacagtcaga ttgatattgc tgaaatgaaa
    59521 acaatcactg ggaaaatagg agagaagtat aaagaaactc ctattgatat tgaagggtat
    59581 gtttttgact cggattcagc gaatacagaa ggcatcttct ccgaaaatac agaggatatc
    59641 tatttttatt acagaaaagg caaactttat ctctcaactg ctcctcaata tgtcaatttt
    59701 ggaaaacata aaatatccag tagaccatta agtgaattcg gacagttttc aggtgggttg
    59761 aaaattatag atgaacgggc ttttggaagt tggaaattac aattgaaaca agagaaagtt
    59821 cttacaaatg gagattttga gcttccagaa gctctttcct ttgttacctc tgaaaataca
    59881 acggttatag ggacatccgc tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat
    59941 ttgtcctctc ttttagattc tacagctcat cgtggaatca gaatagatat tcctgtagaa
    60001 aaccaaagaa tcggaacctt tgaggggaaa ctatcttgga tacttgcaga tgtcccagga
    60061 aattaacagg aagagaagaa tataacaaaa ttattgagtt tcaagaaggg cacaggtacc
    60121 ataggctctt gtgtcccaca gagacaagat tttgttatag tcttctctta catatgatta
    60181 aaggagcgat tttcttgaga ccaaaacaac aattatttat aacactccta gttattttag
    60241 gggcactttt taacaatata tcagtgtcag ctagtgcatt taatttttca gtgacgccga
    60301 taacttcaga gaatcaaatc gacaagagaa aaacttactt cgatcttcaa cttgatccgg
    60361 atcaggaagt agaagtaaaa gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg
    60421 atatttctgt gaatagcgca accaccaatt caaatgtgat ggttgaatac ggaaaaaacg
    60481 agattgaaaa agacatgagc ctgatctttg atctggtaga ttatgtgagc tatccacaga
    60541 tagtgacgct aaaacctaaa agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg
    60601 agcgatttga tggtgtattg gctggtggga tcacattcca agaaatccag acggaaaagg
    60661 accaaacaga aactaaggat caaagcttat cgattgagaa tgaatacacc tatattattg
    60721 ctttgttgat gcaacagaca ctgaacgaag ttgctccgaa ccttactctt catgaagtta
    60781 aaccagatca aatcaatgca agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa
    60841 cctatatcaa tcaagtagtt attgaaacaa aaattacaaa aaaaggacat tctgaagttt
    60901 tatatcaaga ggaaaaagaa ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa
    60961 ctgctttaaa tggtcaaccg ctaaccccag gtgaatatca ccttacaatg actgttttag
    61021 gaaatgaaaa tgaaaatgga aaattttcga gaaaaaaagg aaatactacg atcaactata
    61081 ccaatcaatg ggtatttgaa aaagatttta caatagacgg aaaagtagcc aaggaattga
    61141 acacgacgga tgttacgatt aaaaaagaca ataattggat ttatatctta gtagcttcac
    61201 ttttcttatt gtttatttta ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga
    61261 aagaaaagta aggttaagat aacaaatagt aaatttttat tattgtagga tggttgggct
    61321 ctttttataa caatataaaa tataccattt tattaataaa aatgcatact agtaaatgat
    61381 ataattctaa taacaggttt gatcgcgaga aaggccaaat aaaacgctct ccaaaatgtt
    61441 aaaaaaaaga caggacgatg tatattatac aaacaagaat cgctgacaac agtgactcgg
    61501 atccaggaaa tcagttttat ccccagctag ttggtgaatg catggaaagt aatatacgta
    61561 gaaagagctg atgactaatg aattatgagt tttttttaag caaagaagat cacagaagtt
    61621 attcattact taaatattta gaagcaagct caaatttatc agagtcaata tcgaatgttc
    61681 aagaagagtt gtcgctatcg acatttctct tgaaaaaaac gatcgataag ctgaaacatg
    61741 atttacaaaa gttcgatcta gagaaaaatt tgcgagtaac cgtcagtgaa ttggatatat
    61801 gtctggaaat taatggaaaa tgttctagca aagctctgtt atctcgttat ataacggatt
    61861 ctttatctat gaaaatggta ttggctttct ttcaggaaaa atatatctca gtagaaaatt
    61921 ttgctaaaca gcatcacgtg agttattctg tggcttataa agtattacaa agactaaaaa
    61981 gaaatctaaa aaaatatcaa attttttttg aaaagagaaa gtt
//
LOCUS       DAKCAA010000010        55087 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000010 DAKCAA010000000
VERSION     DAKCAA010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.010"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(54..452)
                     /locus_tag="OUE31_000729"
     CDS             complement(54..452)
                     /locus_tag="OUE31_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HCU0221759.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(449..1222)
                     /locus_tag="OUE31_000730"
     CDS             complement(449..1222)
                     /locus_tag="OUE31_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCU0221760.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1219..1902)
                     /locus_tag="OUE31_000731"
     CDS             complement(1219..1902)
                     /locus_tag="OUE31_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCU0221761.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2069..2956)
                     /locus_tag="OUE31_000732"
     CDS             complement(2069..2956)
                     /locus_tag="OUE31_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCU0221762.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(2953..3822)
                     /locus_tag="OUE31_000733"
     CDS             complement(2953..3822)
                     /locus_tag="OUE31_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0221763.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(3959..5245)
                     /locus_tag="OUE31_000734"
     CDS             complement(3959..5245)
                     /locus_tag="OUE31_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCU0221764.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5518..6096
                     /locus_tag="OUE31_000735"
     CDS             5518..6096
                     /locus_tag="OUE31_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCU0221765.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6096..7025
                     /locus_tag="OUE31_000736"
     CDS             6096..7025
                     /locus_tag="OUE31_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0221766.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7022..8758
                     /locus_tag="OUE31_000737"
     CDS             7022..8758
                     /locus_tag="OUE31_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCU0221767.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8821..9657)
                     /gene="pheA"
                     /locus_tag="OUE31_000738"
     CDS             complement(8821..9657)
                     /gene="pheA"
                     /locus_tag="OUE31_000738"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HCU0221768.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9654..10163)
                     /locus_tag="OUE31_000739"
     CDS             complement(9654..10163)
                     /locus_tag="OUE31_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HCU0221769.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10156..11451)
                     /gene="aroA"
                     /locus_tag="OUE31_000740"
     CDS             complement(10156..11451)
                     /gene="aroA"
                     /locus_tag="OUE31_000740"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HCU0221770.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMSADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11464..12555)
                     /locus_tag="OUE31_000741"
     CDS             complement(11464..12555)
                     /locus_tag="OUE31_000741"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HCU0221771.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12572..13738)
                     /gene="aroC"
                     /locus_tag="OUE31_000742"
     CDS             complement(12572..13738)
                     /gene="aroC"
                     /locus_tag="OUE31_000742"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HCU0221772.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13740..14804)
                     /gene="aroB"
                     /locus_tag="OUE31_000743"
     CDS             complement(13740..14804)
                     /gene="aroB"
                     /locus_tag="OUE31_000743"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HCU0221773.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14837..15859)
                     /gene="aroF"
                     /locus_tag="OUE31_000744"
     CDS             complement(14837..15859)
                     /gene="aroF"
                     /locus_tag="OUE31_000744"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HCU0221774.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16518..17492)
                     /locus_tag="OUE31_000745"
     CDS             complement(16518..17492)
                     /locus_tag="OUE31_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HCU0221775.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17473..19356)
                     /locus_tag="OUE31_000746"
     CDS             complement(17473..19356)
                     /locus_tag="OUE31_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HCU0221776.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDIK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19374..21599)
                     /locus_tag="OUE31_000747"
     CDS             complement(19374..21599)
                     /locus_tag="OUE31_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCU0221777.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21714..22748
                     /locus_tag="OUE31_000748"
     CDS             21714..22748
                     /locus_tag="OUE31_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0221778.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22815..23828)
                     /locus_tag="OUE31_000749"
     CDS             complement(22815..23828)
                     /locus_tag="OUE31_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCU0221779.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKHLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(23906..24094)
                     /locus_tag="OUE31_000750"
     CDS             complement(23906..24094)
                     /locus_tag="OUE31_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HCU0221780.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(24534..24662)
                     /locus_tag="OUE31_000751"
     CDS             complement(24534..24662)
                     /locus_tag="OUE31_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCU0221781.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(24665..26038)
                     /gene="rlmD"
                     /locus_tag="OUE31_000752"
     CDS             complement(24665..26038)
                     /gene="rlmD"
                     /locus_tag="OUE31_000752"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCU0221782.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(26149..27204)
                     /locus_tag="OUE31_000753"
     CDS             complement(26149..27204)
                     /locus_tag="OUE31_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCU0221783.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(27214..28644)
                     /gene="gatB"
                     /locus_tag="OUE31_000754"
     CDS             complement(27214..28644)
                     /gene="gatB"
                     /locus_tag="OUE31_000754"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HCU0221784.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(28641..30113)
                     /gene="gatA"
                     /locus_tag="OUE31_000755"
     CDS             complement(28641..30113)
                     /gene="gatA"
                     /locus_tag="OUE31_000755"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HCU0221785.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(30113..30418)
                     /gene="gatC"
                     /locus_tag="OUE31_000756"
     CDS             complement(30113..30418)
                     /gene="gatC"
                     /locus_tag="OUE31_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HCU0221786.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(30524..32560)
                     /gene="ligA"
                     /locus_tag="OUE31_000757"
     CDS             complement(30524..32560)
                     /gene="ligA"
                     /locus_tag="OUE31_000757"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HCU0221787.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(32577..34811)
                     /gene="pcrA"
                     /locus_tag="OUE31_000758"
     CDS             complement(32577..34811)
                     /gene="pcrA"
                     /locus_tag="OUE31_000758"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HCU0221788.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            34966..36525
                     /locus_tag="OUE31_000759"
     CDS             34966..36525
                     /locus_tag="OUE31_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HCU0221789.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(36635..38566)
                     /locus_tag="OUE31_000760"
     CDS             complement(36635..38566)
                     /locus_tag="OUE31_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0221790.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(38584..39498)
                     /gene="pfkB"
                     /locus_tag="OUE31_000761"
     CDS             complement(38584..39498)
                     /gene="pfkB"
                     /locus_tag="OUE31_000761"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCU0221791.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(39495..40247)
                     /locus_tag="OUE31_000762"
     CDS             complement(39495..40247)
                     /locus_tag="OUE31_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCU0221792.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(40408..40617)
                     /locus_tag="OUE31_000763"
     CDS             complement(40408..40617)
                     /locus_tag="OUE31_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221793.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(40628..41956)
                     /locus_tag="OUE31_000764"
     CDS             complement(40628..41956)
                     /locus_tag="OUE31_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221794.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            42092..42247
                     /locus_tag="OUE31_000765"
     CDS             42092..42247
                     /locus_tag="OUE31_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221795.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(42321..42908)
                     /locus_tag="OUE31_000766"
     CDS             complement(42321..42908)
                     /locus_tag="OUE31_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HCU0221796.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(42991..44241)
                     /gene="clpX"
                     /locus_tag="OUE31_000767"
     CDS             complement(42991..44241)
                     /gene="clpX"
                     /locus_tag="OUE31_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HCU0221797.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(44488..45777)
                     /locus_tag="OUE31_000768"
     CDS             complement(44488..45777)
                     /locus_tag="OUE31_000768"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HCU0221798.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(45931..46863)
                     /locus_tag="OUE31_000769"
     CDS             complement(45931..46863)
                     /locus_tag="OUE31_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221799.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(47020..47679)
                     /locus_tag="OUE31_000770"
     CDS             complement(47020..47679)
                     /locus_tag="OUE31_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCU0221800.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(47682..48707)
                     /gene="sppA"
                     /locus_tag="OUE31_000771"
     CDS             complement(47682..48707)
                     /gene="sppA"
                     /locus_tag="OUE31_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HCU0221801.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(48720..49010)
                     /locus_tag="OUE31_000772"
     CDS             complement(48720..49010)
                     /locus_tag="OUE31_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221802.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            49419..51224
                     /gene="glmS"
                     /locus_tag="OUE31_000773"
     CDS             49419..51224
                     /gene="glmS"
                     /locus_tag="OUE31_000773"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HCU0221803.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(51296..52651)
                     /locus_tag="OUE31_000774"
     CDS             complement(51296..52651)
                     /locus_tag="OUE31_000774"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HCU0221804.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(52675..53844)
                     /locus_tag="OUE31_000775"
     CDS             complement(52675..53844)
                     /locus_tag="OUE31_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221805.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(53841..54728)
                     /locus_tag="OUE31_000776"
     CDS             complement(53841..54728)
                     /locus_tag="OUE31_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HCU0221806.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(54917..>55087)
                     /locus_tag="OUE31_000777"
     CDS             complement(54917..>55087)
                     /locus_tag="OUE31_000777"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221807.1"
                     /translation="KIKKRLEPEESIDVPVKTRKEKTTDLEAEERRAARRAARAERRK
                     KMEQATKEKKEK"
BASE COUNT        15219 a        11957 c         9864 g        18047 t
ORIGIN      
        1 aataacgctc atccgccttc ttgtttgtgt ttatttcctc ttcaaacgct tgtctatgat
       61 tcagactttt ctctatcgtt attttcatct aaaagttctt gcattccgat aatttctcga
      121 tattgatgaa tcttagtgat accaatgact ttgtctacat caatactaaa acaaatacca
      181 ttacctggaa tatcgatgtt gatgccttga ccaatcgcat ccattacttt attcgtcaaa
      241 ctatcgggta ctaatgtcaa cacaatatct ttttctggcg aaatgtccaa acctaaaaat
      301 ttccctgaat catgtacacc agaacctctt ccatgtaaga tcgttccgcc tgctgcacct
      361 gcttcttttg aaaagtcgat aacatcttcg cccattcctc cgtcaacgat cgtcacaatc
      421 atgtgaagat tcaatgctac aagatctttc atttgctttc ccccaatttt tgcaatcttt
      481 ctttttcgat tctgtctttt tcatcttttc gtttataaat atatcctagt actaaagtgg
      541 ataatattgg tgtcaatgca atcattgcaa ccacaccaaa cccgtcaatg atcggatctc
      601 ttccttcaat ttgtgcagcg attgccacgc tcattgataa aataaatgtc gaacacatcg
      661 ggcccgttgc tactccaccg ttatcaaaag ccattgctaa aaagatcttg tccacttttc
      721 gtcctaaaat aaatgctagc ccgtatcctg ggatcaagaa ataataaaga gagaatccga
      781 cgagcaaacg ccacatagac aatcctactg ctgcgccgat cccaattgaa attaccatca
      841 gcatgatttt cgatcggatt ctcccctcgc tcaattcttc aacctgtttg atcattacat
      901 gaatcgccgg ctcagcaaac cctactaaga accccattaa aaagccaagg ggaaccagta
      961 tataattgta aggcaatccc gcaatagcac tgcctaaatg ctgtcctacc ggtacataag
     1021 ccatattgac tccgtgcagg aaaaggatca acccaatagt cgttatcaag aaacctttca
     1081 taatgtcaaa gaaacgcttt ttgcgcatac gaaaactaat gatattcatt aaaacaaata
     1141 ggattacgat aggtgccact gccaaaatga cttccatggt aacgatttcg attccatcta
     1201 tcacttgctg ccagaaactc attggaagat cacccccaaa atcatcacgg caagaatcgg
     1261 ccctaacgaa gcaataccga ccattccaaa actgtcattt tcatttttct tttgtttgat
     1321 catactagtc atccctccgg caagggccaa gataaatgga acagttactg gaccagtagt
     1381 cactcccccc gaatcaaaag caatcggcat aaattcggaa ctggtgaaaa atgaggcgat
     1441 caaaacgcct atgtagccta tagccatcaa ttgataatag gatagcttga atacgacccg
     1501 aagcagcgca aaggctagaa atactccagt gccgacgctg acgatcccaa tcagcaacac
     1561 tctgccaatc tctccgtcag atatatcata tacttgttgt cccaaaactt gcacggaagg
     1621 ttcagcaatc gtgatcacga tcccgatagc aaatcccaaa ctgaccaaaa cggtcaaact
     1681 tttctttttg atcatatatt tccctactag atctccgact tccatcatag aataatctgc
     1741 tccaaacaaa aagagcgtca ttccgatcat catgattgcc gcaccaacca gaaatgaagc
     1801 gaggtcttct ccttctaacg gtgcaaaaac aaacgttaaa atgacaatca ggacagtcat
     1861 cggcaatata gcagcaatca cttctttaaa attttttagc atgtatcctc ctcctttact
     1921 ctttaagttt accttaaaat gaaagagttt tcgagcacaa acttaaaacg ttatcattta
     1981 atttttctca acataaaata acacacgtcc caaaagtatc tttttacttg gaaaaatgac
     2041 tttgaaggaa cgcgcttatt gtgttttttt attttacaga gccgatcatt ccttgaacga
     2101 attgcttttg caaaacaaaa aatacgatgg cagttggtaa agtagcgatg actaatccag
     2161 ccatgatcat tccatagtct ggtgtatagg aagcacccat agcagataaa acaagcggaa
     2221 ccgtccgttt atcaggagat tgcaaagcta ctaagggcca taaataattg ttccagctac
     2281 tcatgaatgt gatgattgca gccgcggcat aggtattttt agccgtcggc atatacactc
     2341 taaaaaaaat acttagttct tttagaccgt ctaatcgagc ggcttctact agatcttttg
     2401 gaaaagattt aacattttgt cgaaagaaga agatcaaaaa agcagtgcta acagatggca
     2461 ggatgacaac caagaaactg ttgattccca aaaccgttcc gttcaattgt gaaaacattc
     2521 gatataaagg gatcatcaat gccgcaaaag gaaccatcat cgatagcagt agaatattga
     2581 aaattaggtc ttttcgttta ctttgataaa tctcaaatcc atatcctgcc attgacgaaa
     2641 tcagcaatgc aaacacagtg gtcaccaaag cgatcatcgc tgaattccaa agggaacgag
     2701 taaaattcag ctcattggaa aacaaatttt gaaaattgat gatcaagtta ctgccaatct
     2761 ttatttttcc cgatgtgata tccacgggtg tattcgtcat tcccaaaacc atccagacaa
     2821 aagggaaaat ggaaataaat gataggatgc ttaatgctgt atactttaat actgacccaa
     2881 ttgtcgaacg aagttctaat gcttgttttt tgacgttggg gcgttcgatt gtttcttttt
     2941 ctaccatatt tttcatcgac tttctcctcc tactttcgtt tggattatcg acaatatcac
     3001 aataaaggaa acaataacaa aggaaactgc tgccgcatat ccaaaattag gcgtgaattt
     3061 ataactcaaa ttatagatgt attgagatag ggtggtcgtt gcatttgctg gtcccccgcc
     3121 agtaatattt tgtacttcat caaaaagctg caatgtcccg atcgtcgaag taatggaagt
     3181 aaacaaaatg attggtttta aatttgggat cgtcactttg ataaactgct gccatttaga
     3241 agcaccgtca atagatgctg cttcataaat ctccgaatca atattttgca tgcctgaaag
     3301 gaaaaaaatc atattgtatc cagtccaacg ccaagtgatc gaaagaatga tcagaactct
     3361 cgcccaaatt ggatgagtca accagccaat cggtgtgtca atcataccaa tgcccaacaa
     3421 caagttgttt acaaggccag attgagaaaa tagacttttc atgatcagag aataactgac
     3481 catcgaagtg atacatggaa gaaagatagc ggttcgaaac aaccctttat atttcaactt
     3541 tttatcattt aaaaggttgg aaataaaaag tgctagaaac aacatgatcg gtacttgtac
     3601 aagtaaatac aggaatgtat taaaaaaagc ttttttaaaa gttgcatctg tcaacatccg
     3661 ctgataatta cctaacccgt taaatgtcat attgacaggg ggaccacttt gaaaagacgt
     3721 gatcaaagcc aaaaccatcg gaataaaaac catgattgat atcaaaatga ctggcaagat
     3781 taaaaaagca tgcccgtttt tgaataaatc tttctgcttc attcttttcc ctccaattct
     3841 atcattgatt atctacatga aaagacaaga aagacaatat ctgtaaggca gacgtgatct
     3901 tttttgtctt ttcgtttgtc tgatgaaaaa gcgaagaaat tcactttttt accaccgatc
     3961 aattagccaa ttgtgcttct acttgttttt gtgtatctgc tagtaccttg tctgtctctt
     4021 ctccattgat gattcgatga agagcttcag ctacgactgc ttcaattgca taggtctcat
     4081 gtccgtaatt cacttctggt atttcagatg tccatgttga aaaatcgtca aagatctttt
     4141 gaccactgta aaattcagaa gcttcttgat aagcttcttg ttcattcgcg ctaagcatcg
     4201 tagatactag tccgatttct ttcgcaagag tgcccatcag ttcttcattc gaagcaaacg
     4261 ttgcttctag gaaatctttc gctgaatctt ctccagctac tcctttgatc acataccagc
     4321 cagcgccgcc aaggttagaa gcttgcgctt tttgcagatt ttctggaagt gcaggtattg
     4381 gtgcaatctt ccattttcca gattggtttt ctgctccttg gatcgttgaa gaataccaag
     4441 cgccagttgg gctagaagct actgctcctg attgtatcgc agttactcca gcattccagt
     4501 cagaggtttg ttcgactaga tcttctttca aaagagtggc aaacaattca agaccatact
     4561 ttaaagatgc attgtcttgg atcgtgactg tctccccatc ttcagatgta taccattctc
     4621 ctgcctgttg cataatcatc cttactcgac caaggtcaga aggattgact tcagcgattt
     4681 tctttcccgt cttttctttg acatctcgcg ctacttgaat atactcgtcc cacttcagat
     4741 tctccatatc ctcttctgta taacctgctt ctgccatcag atccgtacga tagaagtttg
     4801 ctgttacgcc cgaatcgaaa ggaacaccgt atattttatc tcctactttg tttaccgcaa
     4861 atttatacgg tgcaaaatga tcttccttta caatagcaga caaattagcg aatgcatctg
     4921 gataagaagt caaatagcct tgtatcctat aatcttcaat caagacgata ttgggcaatc
     4981 cttctgtatt cccgctcgct aaagcggtgt tcagtttctg aacgatatca tcctgagaca
     5041 tcgtaacaac ttctatctct gtttcttcgt tctcataaac tttttttgct tcattcactg
     5101 ctttgatatt gaatgtctca tcccacgccc agacagtgac tttttcttct ttgtctgctg
     5161 tactactagc acttccgcat cctgttaaga aacctgatgc tgccgctaaa caaacgactc
     5221 cagcaattaa ctttctgatg ttcattttta tccgctcctt ttccatccat tagttgttta
     5281 cgtttgctac attcatcata ccaaaatttg aaaacggttt ctttattatt cagatacttc
     5341 aaaaatttct cctaaaataa taaaaaaata caaatcaact atgacaaaag gaataatctt
     5401 agcatctaga ccaaagatcg aaatggtgag gtttctttaa aataaaaata tccttgcatt
     5461 ttctcctaga aataagtatt tttaaattac aagactattc ttaaggcggg taaaaaaatg
     5521 ccaatacgcg taattcttat cgatgatgaa cagacgattt tagatggaat gaaacagttg
     5581 atcaattggt ctgagcacgg gtttcaatta atagggactt tttccagtcc gctgaaagcg
     5641 cttgattttt ctttggtaca tgcaatcgat atcgtggtca cagatgtaat gatgcctgaa
     5701 ttaaatggaa tcgaattatc gcggctatta aaacagcaac aacctgaaac acagatcctt
     5761 atcctctcta gctatgatga atttgatatg gttaaagatt cttttaaaga aggcgtcgct
     5821 gattatcttt taaagcctcg attgagtcct gatttttttc taaattcctt aactgccgtt
     5881 tcacaaaaaa tcaaaaaaaa gcccaacaaa agcccaatca ccaatcgtta tgagcagatc
     5941 tgcgagaatc tttcacagca gattgctgga caaactcgtc cattgcttga ccctcttctt
     6001 tttgaacaca ccttgttttt ctgttatata ccgaaaaacg gccattcagt tcaaaacaag
     6061 gctctaaaca aaaacagtcg atcacccatt cattgatgga tagcgacgat tcgtttacta
     6121 tttatcctgt ttctaccttt tcggaagaat ccggctatgt aatcaatact gattccaaag
     6181 atacacttag gaagtttgtt caaaagtttc gtcaagaagt ttttccaggt gatttttttg
     6241 ttgtttctga ttcttttgca atccaagata tcaatgaaat attccaagag atcagaaatt
     6301 gcaccaaagg acaacgtttc tatcataagg gaaagaacct tgcttatcag catgaacttc
     6361 ttccgttatt aaccaaccac gagcagcaag caagtagtta tttaacaaaa atcgttcata
     6421 aagactacgc tttagctgtc aaagaacttg agaatttctt cacgacgata ttggaacagc
     6481 ctattgatcc agcttatttg aaacatgagg caatcaatcg tttctatgca ttactcaacg
     6541 ctttggctga cgagcatgtt gggaatgaag aactttcttt gctcaagatc gcccttcctt
     6601 ctttattagc cgatgctgag tatttcgaag atttttctat tcttgtcaaa gaaacacttg
     6661 agaaactcac ccacttttct gcaaatgcaa aaaaagacaa tttcgatatc ttgactttga
     6721 tctacgagtt cgtccaggaa aattatgaga aagaaatcaa tttacaactt ttatccgaaa
     6781 aatatcattt ttcatatagc tatctctcag ccatctttac tgaaaaattt ggtatcaact
     6841 tttcaaaata tctaaaaaaa gtccgtatca gtaaagccaa gctctttttg acggaaacac
     6901 ggcttacttt gacggaaatc tgtgagaaag tcggctatac cgaactgggt tatttctcca
     6961 gagtttttaa agaagagaca ggaatgacac cttctcaata ccgtaaagga acttttgtaa
     7021 aatgagaaaa aaaatcaaag agcatgaact ctttgccaaa cttctgttca ttttgttcat
     7081 cggtcttttt ctgcaagcca tcgtcatttc tttgtttatt tatcatcgat caagggatgc
     7141 ctatatccag ctgttcaatc aatcgaatga tgtggtacta aaaaagattc aatctgaatt
     7201 tgaaagtttg aatgatacaa tcgagaatac attagccgct tttgattcta atccagctgt
     7261 caaaagctat ttttccaatg atccagccca acatatggaa cagcttcagc aactaagaac
     7321 aatccaaaaa atgaatgact ctctttcaaa aatccatcca atgatcgatt acgatgtatt
     7381 gatctttgga gaaaatggaa gaacttttgt cggaaacgac atgctcactg ccgtatctgc
     7441 cgattctttt tttcaatctg cgattgctca gagagtgaat gaacgtgctg ctgatacaca
     7501 aatgcttttt gcacaccacg gattgactct tcgcgataag aaagcaccca gcgtcttctt
     7561 tgtcaaaaaa ctgaaaaata cattgaatca cgtttacgga tatgctgttt tatcgatctc
     7621 atccaagcaa ctagcgaatc tttttcaatc tgtagtaaat cctgagatat cgaagatctc
     7681 cttcatgaac gaagaacaga cgatcatcgc atcaaatgaa gaaaatacaa ttgggagccg
     7741 atcaatgatt ttcaaaaaac taacagtagg tgaaacaacg atttcaaatg gacagcagtt
     7801 gacccgtctt cctctgtacc gccaggattg tacattactc agtcaagtcg atcttcattc
     7861 tttatctaac caaatgggcg tgatttttcc gattattttg tataatatcg tgacacttgc
     7921 ttttgctggc tcattggtat ttatgtattt ggatcgacac acaaaatcga tctaccgctt
     7981 gattgattcg ctaaaacggc tagaggaaga tggcttaaaa gctactgttc ctgtacaagg
     8041 aagccatgaa gtccaattgc tagggaatac gatcaatcaa ttgctaagta atgctcagca
     8101 tcattatgaa cagacgatcc aagacgaaaa gaagaaacgt tcgcttgaaa tccaaactat
     8161 gcaagcacag atacagcccc attttattta taatacgctg actagcttga aatttttgat
     8221 ttggcagaaa aaaacagatg aagcagttca aggaatcgac agtttcatta ctttactaag
     8281 aagtacgatt gggaaaaaag aagaagtgat tccagtcaag gaagaaatca aaagcgtaca
     8341 aagttacatc gatcttttga gtatgcgata tggcgaaaga atctcggcta aaataatgat
     8401 tcctgatgaa ctgcagtcat tatctatgcc gaatatgatc cttcaaccaa ttatcgaaaa
     8461 cgcctatctt catgcttttc acaataaaac gcaaggattc atcacggtgt acggcaaaac
     8521 aaaaaatcag cttcttttat tcgaagtgat tgataacggc gatggcttcg atactgaaaa
     8581 taccaaacaa aaaaatgatc atttttcagg aatcggcatc agccatgtag atgagcggat
     8641 acgcctaatg tatggcgatg catatggctt aacgatccaa tcagtgattg ggacaggaac
     8701 gactgtaacg atttgtctac cgcttcttcc taaaaatcaa tcagaatatc aaaaataaag
     8761 aatagccaag cgctgatttt tttattttaa gttaaataaa tcaatcagta ttcttgactt
     8821 tcatctacgc gtctcttcta ctgtcagcac tggataacag cccaatattt gactttctcc
     8881 tccgagcatc ttgatttctt ggagcgcatt ctctactaat gtcattggac ggtccaacaa
     8941 caaatcgatc acgaaaaaat attctcccaa gctagttttc aatggtcggg attcaatctt
     9001 acttaagttg atttcccgcc agccaaaagc tgccagcatt ttatgaagca tccctggccg
     9061 attagcaggt agtgtcaaga tgacactcat ttttactgga gctgactgct ggctggtcat
     9121 ctttcggtca ccgacgatcc aaaaacgtgt ctggttcaac tcattatctt ggatattctc
     9181 agctaagatc tccaatccaa catgctgtgc tgtttctaat gaagcaatcg ctgctgcgtc
     9241 ttctttcgga tgttctgcta catacattgc tgcagcagtt gttgattctg ttgctactaa
     9301 aggaacatta ggataatgcg tttctaaaaa ctgttgtgat tgtgctagtg cttgtggatg
     9361 tgaaaggatt tttgtaatct ttgttgctgg attgcctaaa agctgctgct tgataggaag
     9421 aacgatttca cttttaactt cgacttctgg atgtttggaa agaagatcga ttgtgtgatg
     9481 aacagctcct tccaatgaat tctctacagg aacgacagcc agatcgactt gtttgcgaaa
     9541 caaagcgcgc aaacaaacag ggatggaagc atacgcagtc aattgttctg taggaaatag
     9601 ctgacaagcc gcctgataag tgaatgaact ttctggccct agatagctga cgttcatatg
     9661 cttttgatcc tttctataat ggtatcgatg atcttttctg gtgtttgatt ggtcgtgttg
     9721 attcgatgtg tcgcactttc ttcataccaa gaaagtcgtt gtgccaataa tgcttttatt
     9781 tcttctcttg tttttccaag agctaaaggt cgaatagacg tttcatcttg ttggatacga
     9841 tcaactagac agtccgcttc tgcctctaag taaagaacaa tcggctgtgt ttttaaaaaa
     9901 cgccgatttt ctgcactttg gacaatccct ccaccagtcg cgataatttt gtcttcattt
     9961 gacagctttc ttaaaatatc tgactccact tttcgaaagc ttttttcacc gtaatagtga
    10021 aaatattcgg caatcgacaa ttggatatgt tcctcaatct ttgtatctaa atctacatac
    10081 tctttttgta aacattgagc taacccttta ccgattgttg tttttccagc gcccatgaaa
    10141 ccaatcagca aaatgctagc catgagcttc tcctcctgac acaagttctg ctaaatcgtc
    10201 aaaaaatgcc ggataagaga ttgaaacagc ttcagctcct tctagttcgc aaggtccatc
    10261 agctatcaaa gcagctactt gcagcatcat accgattcga tgatcgcctc tgctggacac
    10321 ttttgcgcca tgcagaggtg tcggcccatg gatgatcaga ccgtctgctg tcgcttttat
    10381 ctttgctccc attttctgta attcttctgc caccgcatca attctgttgg tttcttttac
    10441 ttttaattct tctgcgtctt tgatgatcgt gattccttct gcttgagtag ccactaaagc
    10501 tagaatgggc aattcatcaa tcagacgcgg aatgatttct ccaccaatcg ttgctttctt
    10561 caaatgactc gtcttgacac ttaaatcagc cgattggttc tgttcattgt gattcgtctg
    10621 ggtaatcgct gcgcccatct cctccaacac atctaagata ccagttcttg ttggattgac
    10681 cccgacattt tttaacaaca gttggctttc cggaacaaga agtcctgctg ctagaaagaa
    10741 agcagctgat gaaatatcac ctggaacagt tatctgttga ccagttaatt tttgcggtcc
    10801 ggtcactatg atcgttttat cttccactgt gatccttccg ccaaattgac gaatcatttc
    10861 ttccgtatgg ttacgggaac gttctttttc aacgattacg gatgtgcctt ctgcttgtaa
    10921 tgccgcaaac agcaaagcag atttgacttg cgcactggct acaggcatat tgtatcggat
    10981 aggtgataaa gagcgggttc ctgtcacagt gattggtaga tactggtcat tttcttctcc
    11041 ttgcaagtca gcgctcatct cgcgtaaagg ttccatcact cgccccattg gacgtttaga
    11101 caacgaagca tccccgaaca gagtagtcgt aaaaggctgt ccagccaaaa tacccatcaa
    11161 taaacgtatg gtcgtaccgg agtttcccat gtcaattgat tcggttggtt ggacaaatga
    11221 gtggctaccg cgaccatgaa tcttgatcac ctcttcctct tcttcgatct cgacacctaa
    11281 ttgttggaag gcatgtaaag tactcagaca atcttctgcg cgcaaaaaat tttgtatagt
    11341 cgtcgttcct tcagcaattg ctccaaacat gatgctgcga tgggaaattg atttatctgc
    11401 tggtatccta acagtccctc ttaatccatg tatttgttgt aataattgca tttatccagc
    11461 ctcctatttg atccagcaat gataactggt attagacata atgattcttt ttgcttgtaa
    11521 caaatcctgt tggtttttaa aactgatttg cagtattcct aaaatatctt ccctggtctc
    11581 ttggatcttc aaattaatca aagaaactcc cgcttttccg atcagtccag ttacttctgc
    11641 aataacgcca ggttcatctg gcacatcgat aaataaatca aaaaaggcag gaatcgcgcc
    11701 ttgcttatgg acaggcaact ggtctcgact ttcttttgcc cgattgaaaa aagaaaagat
    11761 ttccgattgg ttctcagtca tgatccattc tgctatttgt gtcatttctt gttgccaatc
    11821 tgccaatcgt tccaataata tctgcttatt gctcaacaaa atatctgtcc acatgacagg
    11881 atctgaggaa gcgatcctag tgatatctcg aaagcctcct gctgccagtt gtttggctcg
    11941 cggatactct tgattgaatt gttctgcctg attgactaag ccagctgcca gaatatgtgg
    12001 aaaatgactt agcattcctg ttatacggtc atgttctctt gctgtaagag ttacatattt
    12061 tgctttggtt ccgcaaaata gttcttgcag tttttcaaca tcttttttcg tcttttccaa
    12121 aggtgtaaag atgtaatagg cattttcaaa tagtttagca tctgctgcct gtatacctga
    12181 tttatgagaa ccagccattg gatgtccacc gacaaaccga agatttttct gctcagcgga
    12241 tgtcacgact tgctgcttcg tactgctgac atccgtaatg atgacgtgat cagacaagtt
    12301 gattctttca aggacatcaa gataagctaa ggttgtacgg acgggaacgg ctaataagat
    12361 aacgtctgct tgttctgcac ctgtttcaaa atcacttgca acgtaatcaa cgatctgctg
    12421 ttctactgct tgctcacggg tttttgactg actatcccaa ccaactacta tcagttctgg
    12481 attggtctga cgaatacaaa gtgccataga agcaccaatc agtccaagcc ccacgataaa
    12541 aacatgttgt gccatcttat ttgccccctt tttagtaatg tttcaagtag tcacggtact
    12601 ccttcactgc agctttcaac tcaacaagcg aatcacttgg gaattttgac aatagctctg
    12661 tcgctaccac agtggctaca acattttccg caacgacgct agctgcagga actgctgtac
    12721 tatccgaacg ttctacactt gctttgtaag gttcttttgt atcgatatca acactttgaa
    12781 gtggcttgta caatgtagga atgggtttca tgaccccgcg aatgacaagt ggttcgccat
    12841 tggtcattcc gccttcgaag ccgcctagat tattggtacg tcggaaatag cctctttctt
    12901 cttcccatag gatctcatcc atcacttctg agcctggtaa tgaaccagaa gtgaatccga
    12961 ccccaaattc tacgccttta aaggcattga tactaaccac agcttgtgcg attttggcat
    13021 ctagcttcgt gtcccattgt acgtagcttc ctaatccagc tggaacgcct ccaacgagca
    13081 cttctacaat tcctccgatc gtatctccat ttttctttgt ctgatcgatc aaatctttta
    13141 ttctttgctc aactgctgga tcaacaactc gtacttctga cgcttcagaa atttctttga
    13201 tttcttgaat cgagatattt ccaggtattt ctgcttggat tccaccaaga caaatcacgt
    13261 gtcctgctac gatgatgtca agttcttcca gaattttctt ggcaattgcg ccgattgcta
    13321 cacgcatggt cgtctctctt gcagaggacc gttcaagcac attccgaaga tctcgatgat
    13381 ggtatttcat accgcctacc aaatccgcgt gtcctggacg cggacgtgca actcgccgca
    13441 gtgattggtc tttttcaggc acttctgcta cagacatgac agttgtccaa tttttccaat
    13501 ctttattttc taccactaaa gtgacaggtg aaccaattgt tttgccgtga cggatgccag
    13561 acgtgatccg aacacgatct ttttcgatct tcatccttcc tcctctgccg taaccagctt
    13621 gtctgcgagc gagttcgtga ttgatttctt cttctgacag aggtaatcct gctggtagtc
    13681 cttcaataat ggctgttaat tctggtccat gggattctcc cgcagtcata taacgcatct
    13741 tacagtcctc ctaagtaatc tttgaatgtc tctgtgggaa caggaacgat ttttgcttgc
    13801 ccaatctttt ctagcaagat gatattcaat tggcttcctc ttgctttctt atcatgggtt
    13861 atcgcgtgga ataattcatc tggatgactt agatcgtacg taatcggcag atggaatttt
    13921 tgaagtatcc tttctaaagc agctgtcgat ccagttggag acaagccgat tttttctgca
    13981 tgagaagtga tggctaccat tccaatagct actccttctc catgactgac taccccatat
    14041 cctgctgtat tttcaattgc atggccaatt gtatgaccaa aatttaaaat aagtcgattt
    14101 ccttggtcaa agacatcttc ttccactact tttcgtttga tttccaacgt agcagtaatg
    14161 attggaacag catgttccag aagatctttt tcgtctttca gctcgttcag ctgtttccaa
    14221 agcgttgcat ctgctatagc tgctgatttg atgatttcag cgattccttc tcgtaaacga
    14281 cgtaccggca aagtttttag aacctcagga tcaatcaata caccagctgg ctggctaaat
    14341 gttccgacaa ggtttttcgc tttgtttgta ttgactgctg tcttcccgcc aatactagaa
    14401 tctacttgtg caagtagcgt agtcggaatt tgaacgaaat ggatcccacg catgaacgtc
    14461 gaggccacga atgctgctag atcacccacc attcctccac caagtgcaag tatcccatcg
    14521 ctgcgggtaa aatcattatc tgctaaaaaa tcgtataact cagctgcttg ttctaaagat
    14581 ttactggtct cacccgccgg tacgattgaa aggactggtt caaaattagc ttgtctcaat
    14641 tggaacatga ttttttctgc atatagtgga gcaacgtttg tatcagtgat cacagctact
    14701 ttttgaggtc tccaaatcgt ttgaagccat gatccagcct gttctagtgc gcctttttca
    14761 atatgaatat cgtatttttg gttatcaaca tgtacagtaa gcattcgttt cacttctttc
    14821 ttttaaaaag ctggaattaa tcgagtgtct gaatcttttc cattgcttct ttcatgatcg
    14881 caacttcttt catcatgcgt gagtaagtct tttcattcaa cgattgggga ccgtctgacc
    14941 aagcatttgc aggatcagga tggatctcta cgatcatgcc atctgctccg cttgccacac
    15001 ccgcacgagc cattggtggt acaagttccc aaattcctgt accatgactt ggatcaacaa
    15061 tcacagggaa atgagttaat tttttcatca atgggacagc acttaaatca aacgtattac
    15121 gtgtcgctgt ttcgtaagtc cgaatcccac gttcgataaa aatgacagga gatttgtctt
    15181 cgactgcaat gtattctgca gcattaagcc attcattgat cgtaccggaa attccacgtt
    15241 tcaatccaac aggtttacct gttttaccga cagcagatag cagtttaaaa ttttgcatat
    15301 tacgtgcgcc aatctgtagg atatcgctgt actcagccac catatcgata tgcccttcat
    15361 ccatcacttc agtaatcact ttcattccaa attcatcagc cgcttgacgg atgtatttca
    15421 atccttcttc ttctaaacct tggaaagcat atggagaagt acgtggtttg aaggcaccac
    15481 ctcgcagaat ttttgcgccc ccggctttgg ccattcgcgc acattctctg atttggtcta
    15541 atccttcgat agaacaagga ccagccatcg tcacgaaact gccgtcacca atttttactc
    15601 cgtctacatc cacgactgta ttgccaggat ggaattctcg agaagtcaat ttgtatgtgt
    15661 ttaaaatacg cacagcattt tctactcctt catagcgtgt aaatgctcct tcttgtaaac
    15721 ttcgcgtatc accttttagt ccaatcacta ctcgttctgt tccttgatcg attgagactt
    15781 tgaatccttc tttttcgata tgatcgacga ctttttttat ttgttcttcc gttgcttctt
    15841 ttttcataat tactatcatt gtttttcccg ctttcttttg tttacttatc tatcttggct
    15901 gattttctct actttttcaa ggtggtttta cattaattcc tactaaatga ccgtgtcctg
    15961 ttgttctcat tttcgctcct tctttcctac ttatgaccca gataatcaac aaaaaaagat
    16021 gtccctgtag gaaattgcct ctacagtgaa catcttcaac gagccttaaa aagcgctgca
    16081 aaaatataaa atagccacta tagatgaatt tctctacgtg gctgtaagtc gtgtttaaaa
    16141 atctttagcc atcatagata caaacctggt ttgtttgtac ccacgaagtc atgaatacaa
    16201 acctatctaa aatagctaaa gtaatacgta ttcagttttg taagttttct agatttcata
    16261 aaaaatcgct ccaaactgat gtaagaattg tacctagtat agacataaaa aaatcgactg
    16321 tcaatcattt ttatgaaact ttttttaatt ttctgatagt taactttgtt tttcagaaaa
    16381 ataacaattg gttttattga agaaaatagt catgaacaaa agtatctgag aactttttta
    16441 ctctcttgtt catgacatat agaataaagc agctttgtct tgtaaactcc gtttttcaaa
    16501 taataatcta aagattgcta ctgaataata aagccgattt catggtcctc ttcgctgctg
    16561 attcggtaag gtgactcaac atccgctccc cagctattga tacccccgac tcctcttact
    16621 tttgcaaaaa tcgtaagaac cgttcgtctt tctggcggta gttcttctat atgtgttgcc
    16681 tgttccagtt cttctgcttt gaatggtaaa gcggaaaaag caaatggcgt atcctgctgt
    16741 tcaaatcgca acgaaaaatc ttcttgatct ttatccgtat tatccaacgt ttgatttctt
    16801 gttagttcta cccatttcgt ttccatatgc atgccgcatt cttggggaac aaggtatggg
    16861 gaaacgggga gtcctgccac tttataaata ccttcgacac caccagccat ccgatccgga
    16921 tatgtttccc ctgataggcc ttcatactca aaaaattttg ctttcgttgg cataatgaac
    16981 cttaaaccca atgcgggtaa ttccggtaat cctttttgtc cataataatg catattgaca
    17041 agcattttac cctctccagc gatttggtag gaaattgtca cttgggtttt tggtactgtg
    17101 ttgatttcca gtgtaaaaat gatttcaacc gtttcagcgt attcattact tgaatattga
    17161 ttatttactg gagcaatcgg caaatcgatc tttttattgt ccaccagtac ttctatttct
    17221 ttgacttttg gatacaatcc ggctcctaac cacataccgg atttaaatcc aaatccgcta
    17281 cctctgtcat tatcggtcgt tgctcgccaa aaaactggaa gtgtttcccg gtatagccat
    17341 tcttttccgt ttttattgag cgattccagt ccgcctcttg tataagaaaa aatataatgc
    17401 gtattccccg atttgacacc taatgtacag tcgccgaaga cgattgcaac tttttccgta
    17461 tccatatgac ttttatttac tgtatttttc ataataatat cttacctcct gcatggcggg
    17521 tttttcttgt ccatctgcaa aaacgatccc attccctgag aattcatagt cacttggttt
    17581 atcgtcaaag tcaccgccat agcgcatcac ttctctgcct gtgattggat cagtcacttg
    17641 gatcgcctga tctttaaaat cccatatata gcctccttgg tacatttcat aacgatcaag
    17701 caacgtcatg taagaatcca ttccacctaa cgaattcccc atgtcatgca tatattcaca
    17761 taagatgaac ggtttttccg ctttattttc aaggtagtca atgatctctt ctggtggcgc
    17821 atacatgcag ctttttatat ctgaaatcga atcttcgaat gctggatttg gaaaattccc
    17881 ttcataatgg acaagtcgat cggggtctac ttttttgaag taatcgttca tttgtcgaat
    17941 gttttcttcc gcataagatt catttccaag agaccaaaaa agaatacttg gatggttttt
    18001 taatgtttcg aaattcgttt ttgctcgatc aagaacagcc gcctgccact gaggtactgc
    18061 acctggtacg ttgtaagaag gctcaaatgc gcccattttt tgccatgagc catgggattc
    18121 gaggttcgtt tccgccatca catggattcc tgcttggtcg cataaataat accaagtgat
    18181 ctggttgggg taatgagatg tccgtacgcc gttgatcttt gcatttttta tgatagccaa
    18241 atctttttcc atatcttcta tagtgatggc gcgtcctttt ttcggatgcc actcatgtcg
    18301 atttaccccg ttgataatca tccgttttcc attgaagtag atgattttat ctttgatttc
    18361 gattttacga aaaccgaagg aatagtcaat atactccgtt actctttttt cttcgtctat
    18421 cgtctccaat tcaagcttat ataaattggg ctgaaaatgc ccccacagtg ccacattttc
    18481 aaatccatcg atgcgaatcg tcatttgctc ttttaacgga tattgctgtt gatagatttc
    18541 cttcccatca ggatctagta tcgctacatt cagctgactg tttttggcta cttgctcaaa
    18601 agacaaatct acttcaagtt tgccattttg acatttgtca tctaagcgag gtttgatcca
    18661 aagatcttct aaatggtttt gtcctcgagc aactaagaag acatctctga agatcccaaa
    18721 aaatcggaaa aagtcctgat cttccaagaa tgcagctgta cttcttttgt aaacctccac
    18781 agctagaata ttttcttctt ccaaataagg tgttaaatca aattcagacg gagtgaacga
    18841 atcttcggca tacccgataa aatgaccatt caaccaaata aacattgctt gttctacacc
    18901 agcaaaatga atcgagattt gttttccctt tagaccttct tctaatcgaa aagtcgtcaa
    18961 atacgaacca accggattgt ctttagcagc tgaaaagatc ccttccgcct ctttctcagg
    19021 gcttgtcgtg aaagggggac ggcgaaatac atgtccctcc cacggataca tcgtattgat
    19081 gtaatggatc ttgtcataat ttgctaattc aatatgacta ggaacagtga tttcatcaaa
    19141 agaacaggca tcaaaatctt ttttataaaa tgtttttggt cgtaccgaag gatttggcga
    19201 ataacaaaaa cgccatgatc catttaaaga ctgtttaagg gaggatgtgg tttctacttc
    19261 ttcccttgtt gcataacaaa catgatcgct atgtgcattt gattggttca ctctaaaaac
    19321 ttgtggatca tctaaccatt ttatatttgc tttcatactt ttttccttct ctctcataac
    19381 tttttgaaat gaagcagttc tgtttggaaa tcaccttgaa aatcggggaa gtaaagtcca
    19441 actgtcatca attcggcccc cgaaaatatc cgcttcgagg tctgttcctg ataaagtgcc
    19501 tcatcatcta accccatcag atatacttca tggaacgctg gttgagctga agctagtatc
    19561 ctccctaaaa acacaatagc ttcatcttgt ttaggagaca caaacatcca tgcggcaata
    19621 ttttcttcaa aaggactcgc caaacgataa taatggccat actggatcac cggacgaatc
    19681 gtttgatagg atataatttg gtcttttact tgcttttttt cttcaggaga cagctttgtc
    19741 aaatccagtt cataaccaaa aacagcgctc atagctgttt ctcctcttgt tttcaacgaa
    19801 gtagatctgt cggtctgatg atttggtaca gctgatacat gagctgtgat ggacgaaatc
    19861 ggataagcaa ggcttgttcc atattggatt ttcatacgct ccactgcatc cgtgttatca
    19921 cttgtccatg actgcggcat ataataaata aacccggcat caaaccgtcc acctccacca
    19981 gaacagcctt cccataagat ttccggataa tcagttgtca aatgttcaag tagttcataa
    20041 agcccgagca tataacgatg cgctacttct ccttgtctct gtgggtcaag ggtaatcgaa
    20101 tagacatctg aaagcgaacg gttcatatcc catttgatgt agtcaagagg aatcgtatct
    20161 aaaatctttc tcatttgttt ctcaatcgtc tgccgaacat ctaaccttgt aaaatccagt
    20221 acatgttgtg atctggaagc agaaggcatt ctacctggct cctgcataag aaaatcagga
    20281 tgtgttcgat acagttcaga atcaaccgag atcatttcag gttcaaacca taaaccaaat
    20341 ttcaatcctt tgctatgagc ataatctgct atttcacgta atccatttgt caacttgcct
    20401 tcatactcga accagtctcc taatgaagaa ttgtccgcat ctctttttcc aaaccagcca
    20461 tcatctaata cgaacatttc gatgcctagc tcctttgctt catcaatgat cgccttgatt
    20521 ttttcactat tgaagtcaaa gtaagtggct tcccagttat tgaccagaat cggccgttca
    20581 gcaaattgat gacgacctct tgcgattctt tcacgtagca actcatggtg gatctgactc
    20641 attttgttca atccctgact tgagtaagaa aggatcattt caggtgtttg aaaagactgg
    20701 cctgcattca attcccacga aaaacgatgg ctgttgatcc caccgacgac tctcaattga
    20761 ttgatctgat ctttttcaag ttcgaaagaa tggttgccgg aataaacaaa ttgaagtccg
    20821 atcgcttctc cagtattttc tgtcgtatga tgatgaacta aagcaataaa gttattcata
    20881 tggtgactgc tcgttcctcg acggctttca aatacttttg ttccagataa aacagattgc
    20941 cgtgaaatct gtctttcatt gacatgtgct cctggcaaag caatgacttc atcaaatcgc
    21001 ctagtatggg caaagtctag ctggaaacta gccgcttttt ctagtttgat tgtttctccg
    21061 gtttcatttc ttatctttac agatcgtgtg atcactgctc tatcagtaaa tatggtatag
    21121 aacaaatcga aataaatcgc tgtttctcta tccttaagtg aaatcaccaa cgtttgtgcc
    21181 tctgacttgt ccatcacata agtttgaggc aagccttcga tctctggctt cccatctgta
    21241 atataatggc tgtcatatct cagatccagt aagtctgatc cattcttgcg ctgaatgatc
    21301 gatgcgggcg ttcgaaagtc catgctgcca tgagaagagt attcttgcgg tagtgtatct
    21361 ttcgacagag accggtcagg atttaaggga acatttcctg aaaatccacg atctcttcgg
    21421 ggataatttt tattgtcttt gtactgcttg actggtttgc caaaataaat atgcgccaat
    21481 acattgcttt cttctatctt tatcagataa gaaagaaatg tatttcgtaa atggaagact
    21541 cggctctttt catcaaataa gatgaaattt ttatctgttt ttctatgcgt aatatccatc
    21601 atttcactcc caacaaaacg gaaaccgttt actttttttt ataattcctg tatactgttt
    21661 actaaacaat tttgtcaata aaaatttttt atttttttga ggagtgtgta aaaatggttg
    21721 gaattagaga tgtcgcacga aaggcaaatg tctctcctgc tacagtttcc cgtgtgttga
    21781 ataacgatca gacgatccat gtggctcaga ctactcggca acggatagta gaggcagctg
    21841 ctgcgttgga ttatgacatc agtactcgta aatatatcaa aaagagaatg ccttcgattg
    21901 gtgtgatctc tacgatcggc aaagcgagcg aagaacagga tatctattac aaacatttgc
    21961 gagtagggat ggaagaagaa gctcgacgtc tgcatttagg gatgaatcga atctataatc
    22021 tatctgataa tcctaaacaa tgggaagatc tagatcagtt aggtgcggtg atcgttgttg
    22081 ggactgttac gaaagaatcg attaccgcct tgttaaaaca aaacatgcaa atagtcgtcg
    22141 tggataaccc tgacatccag caagaggtcg atatggtgta tgcagatctt gaacggatga
    22201 ctaaaaccgt actggaattg ttcttagaaa atggtcataa aagaatagcc tatatcgggg
    22261 gatataaagt cgatatggat gaattcggtg ggaagcagat ttctataaat gaaaagagga
    22321 tgcgtgccta tcagcatttt atgatcgatc atcacttaga aaaatatatg tcttatcatc
    22381 taggtggctg gacagaaaaa caaggtgagg tacttgcgac taatctatta gaaaatgaat
    22441 cccctcttcc tactgccatt cttgtcggga gcgatccaat ggcaattggt gtctatcggg
    22501 cattgaaaca aaaaaatatc caaattggag aagagattgt tgtagcaagc tttgataata
    22561 tcgagacaat cgcaaacctc tcccctggct tgaccagtgt tcaaatcaat gcgaaatcaa
    22621 ttgggcaagc agctgttcga atggcattgg agcgaattga cggtatacgg gacgaaccaa
    22681 tcattttgac ttatcctgca cgattgattg ttagggaaag ttttatccca agaacaaaaa
    22741 ggtattgaaa gagaggttgt gaaaagccgc ttcgtttctt catactcaaa acgaaacggc
    22801 tttttcacaa cctcttactt atacttattc acaaaatcca atgtctgctg gtaacaattt
    22861 tgcgattctt ttagcgtgta atcaaattgg tattcatggg taatctcttt ttttgtatct
    22921 gtataaaaca aggattgcac gggtaccttt aattctgtca accgattttc taatgcttga
    22981 ccttgctcct ggaatgagta tgcatttccg tcagttatat acgttggcgg aaattcctta
    23041 gaaacatggt cagccacact agcttctttc aattgctcac tcgttttcca atcttttgtt
    23101 ccaatcaacg accacgcaac ggttttgacg aaaaacttca taaatcgatc atccgaatgc
    23161 tgctgtgctg ttagcttcaa atcaacaggt ccgcaataag aaatggttcc tttcagacta
    23221 tcttttggaa gtagatgttt gattttcatt tgtttagcat acgcatcatt cgtttgtata
    23281 gctgcatatt gcaatgcgat ttgtgaacct gcactatctc caccaaaaaa taattgttcc
    23341 atgtctagca atttgtcgtc tttttcttca gctaataaat ctttgatcag ttcattcact
    23401 tgaagaactt gattagggta ttctgaatca ggcgctaatt cataattcat cgcaaccact
    23461 gcgatgttgg cgtctgaaac taattttgtc gcaaattctt tgacacccga tttatctccg
    23521 ccgacgaatc ctccaccatg tacccaaaat agaacaggaa caggcccctt gctgtttttt
    23581 ggatagtaga tgtcataagt attctcttta tacttggact catacgtcaa atctgttttt
    23641 ttcgccacgt ttttttctgc ttgatcgaac gtttttttat cagtgatttg aacagtattt
    23701 gaaaacatat ggttgatcaa gaatgctcca ggtctggggg aaagctggaa ggcaagaaag
    23761 attgcaaacg cgatcccaag aatgattccg aagaaccatc cgataaattt aagaattttc
    23821 tttttcataa ggctccctca gtagttagta ttaagcattc tgattatacc atagtgttat
    23881 ttcctatcaa gctctcctag atgatttaat gattttcccc aaacttcttc tgcaatgctt
    23941 ttgacaaaag aaattttttc cattgttctt caaacaaaac attttcttct tctgttgaag
    24001 caaatccaca ttgaggactt aagcacaaac gatccaaagg cagatatcgt gtcgcttcgt
    24061 agatccggtc aatcacttgc tggtgctctt ccatttcgcc atttttcgtt acagtcaaaa
    24121 tctaagacaa ctaatttatc ttcagagact ttctctaaaa gaacaaaact cccagcacgt
    24181 tcactatcgt attctaaata ataggcacgg acattttctt gagtaaaata atgggtctgc
    24241 tacgtcgtca tcccccctga tgccgccaaa atcgaataat aatttccgcg tcaaacatgt
    24301 atatttagtg ttgaatcatt tgagaatatg aaaataaaaa tctttttgat caatcagtta
    24361 atcaaattga aataacgaaa aatctgagac agaatgacgt tcattctgac ccagatttga
    24421 ttttgcacaa ctcaacagtc cttattggca aatcgccaaa ataatgtaga ctaactaaaa
    24481 agactaagaa acaataacaa aagttaacac ttcttagtct ttctttagca cgtctattta
    24541 ttaaagattt tagggccttt tctcatgttt ttacgatcat tcttaggtgt ttccatttgt
    24601 ttggatcggc ctccaccttg tttctttttg atcaattctt tcattttttc tttttggtcc
    24661 atttttattc tcctttaacg aatgaagcga ctaattcgat atgatgggtt tgcgggaaaa
    24721 gatctacagg ctgaactttc ttcacggcat aacctgcttc tgcaaataac ttagcatctc
    24781 ttgcaaaagt tgccggatta catgagatat agacgattcg ttctggtgac atttcgattg
    24841 ctgattcaat aaaatgatga tctaatcctt ttcgtggagg gtcaactacg atcacagatg
    24901 gtttgatccc tttttcttgc cattttttca taactttttc tgcttttccg acttcataat
    24961 gaacattttc gattttatta tttaaagcat tgaactgtgc atcttcaatt gcttctggaa
    25021 taacttccat cccatacacc ttatccactc tgtctgctaa agacaagcca atcgtaccta
    25081 ttcctgaata agcgtcgatc acaatgtctt ttttatctaa ctcggcaaac tcgatggctg
    25141 tttggtacag atactctgct tgttgagtat ttacttgata aaatgacttt gctgagattc
    25201 gataggtttt tcctaatagc tgatcttcga tatagtctct gccatataaa actttttctt
    25261 tgtctcctaa aatcacattt gttttttctt cattgatatt ttggatgacc gaaaccactt
    25321 ctggcaattc ttcatgaata gcttcagcaa tttccttgga tttaaagaat ttttctttac
    25381 gagtaactaa aacgaccatc atttcatggg aataatgacc acgacggata atgatgtgac
    25441 gaagctgtcc ttcatttttt tcttcattat atcctcgtac ttggaaccgt tgcaagatat
    25501 ctctgactac tttgattgct tgatcgatga caggatcttg gatataaaaa tcttcgatag
    25561 ggactagatc atggctattc tttttgtaaa aaccggtggc taactgtcca tcgatacggc
    25621 gaacagggat ctgtgcttta ttacggtagc cgaatggttc tgccattccg accgttggaa
    25681 gtacaggaac ttctggcatc ttagcaatct tcgccattac atgctctact tgtttttgtt
    25741 tgaagacaag ctgttgttca tacttcaaat gggctaaagg tgcgatacct atgcgaagta
    25801 atgcattgtt ttctacaggc tgacgatcag gtgattgtgt aataaatgtt tcgacttttc
    25861 catatccaaa cttattgcct gcttttacta ctagtatttc tacttcttct ccagggagtg
    25921 cattttcgat aaataatgga taaccatcga tttttgctac ccccattcct tcataactca
    25981 agtcgacgat ttcgactgta tatcgttcgt ttttctttac tatttgctgt tctgtcatat
    26041 tttgctcctt taagcctatt tttcaatcct actgaactct actataaatc agctaattac
    26101 acaactaaaa ccggcactga ccttactacg ttcagcaccg gcttttgatt aattcttttg
    26161 attaggtgtt tcgtctgcta tttttccgtc accgtcgata tcttcatccg ttaaacgttc
    26221 gacttctttt acgaattctt tgctgacaac ctctaattct tcttcatctg tacctgtgat
    26281 tgcttcatca ggaatctgat cggtattggc aaagaactca atgtgttgat gaagattttg
    26341 gaaatgcatc ggtgcttccc cgccgtattc accatctaag ttgatcatta ctggtcgatt
    26401 gatatcatct tctgtttcaa cgaacaaact gcttgttttg gtatagatta ttcttggatc
    26461 atcgacatgt cgaccgccat tcagcatgag tgctgcaata tgcaagatct caaagatatt
    26521 tgctgtcttc acaatgatta aagaaaactt cccatcatcc aatttggcat ctggcgcgat
    26581 ctgttcgaat cctccaacag agttcgtcag ccctaggaaa aacatcgaag catttccgat
    26641 atattcccct tcatcatact tcaagcgcat tttgattggc tttactcgag ggagcatctc
    26701 tgctcctttc gcaagataag caagataacc aaaaatactc tttagttctg atggaacttc
    26761 ataagtcaat tctgtcaaat agccacctgc agcgatattg atgaagtaac tgttatcaga
    26821 aaggccgatg tccattttta cggtttggtg tttttttatc acttctgctg ctgctttaat
    26881 attatctcta ggaattttta atgctcgagc atagtcgttc gttgtaccag ctgggatgat
    26941 ggccatttta ggacggtgtt caagcggagc gattccatta accacttcgt tgattgtgcc
    27001 atcgccacca gctgccacta ctagatcaaa acctagttct gcgactctac atgcttcatt
    27061 cttggctgaa tctggttctg gtgtagttgc ataggcgctg gcttcaaatc ctgcttcttc
    27121 taatgcctgt aggatatccg ccaaattttt tttcaataat tcttttcccg aggtggggtt
    27181 ataaattacg cgtgcttttt tcattttcag cctctatcgt ttcgctaatt catctttaag
    27241 tagcttattc acgacaccag gatttgcttg tcctttagtt gctttcatga tttgaccgac
    27301 taggaagcca accgcacgat cttttccatt tttgaaatca tcgacagatt gttggttgtt
    27361 atccaaaatt tcattaatga ttggcagtag tttgttcgga tcagataatt gcacccaacc
    27421 atttttttca actacttctt gggcttctcc gccatttgtg atcaattcac ggaagacttt
    27481 tttggcgatt tttgagctga tcgttccatc ggcgatcaaa cgaatcattc ctgctaagtt
    27541 ctcaggtgtc aattttgtct cagctaattc cagtttctca ctgttcaagt aagcagaaac
    27601 ttcacccatc aaccagttag atgcttgctt ggcatctgca ccattttcca aaacagcttc
    27661 aaaaaaatca gacatttctt ttgtaagtgt caataccatt gcgtcatact ctggaagtcc
    27721 aaactcacgg atatagcgtt cgcgacgaga agctggcatc tcaggcaaac tagcttttac
    27781 tttttgaatc cattcgtcat cgatcacgaa tttcgggata tcaggctctg ggaagtaacg
    27841 ataatcacta gacccttctt tgacacgcat caaaactgtt ttattcgttg tttcgtcaaa
    27901 acggcgtgtt tcttgttgga tttctcctcc tgaaagaaga acttttgctt gacgtttttc
    27961 ttcaaaagct aaaccttttt tcacgaaaga taaagagttc aagtttttca attctgcttt
    28021 cgtaccgaac tcttcttgtc cataagggcg aagagaaata ttggcatcac agcgcataga
    28081 gccttcttcc attttcacat cgctgacttc tgtaaattgg ataattgatc gcaatgcttc
    28141 tagataagcg tatgcttctt ctggtgaacg catatcagct tcagaaacga tttcgatcaa
    28201 aggcgtgcct tgtcggttca aatcaacgta agaataaccg ccaataccat gcatgttttt
    28261 tccagcatct tcttctaaat ggacacgttc gatccggatt tttttctttt taccttctac
    28321 ttcgatttcg atccatccgt catgaccgat tggttgatca aattgggaaa tttgatatgc
    28381 ttttggatta tctgggtaaa agtaattttt ccggtcaaaa tgagtatctt tagagatttc
    28441 acagtttaat gccaaagctg ctttcatccc gaattccagc gcagctttat tcattactgg
    28501 cagcacgcct ggataacccc agtcgatcac gtttgtattg ctgtttggtt ctgcaccaaa
    28561 atgagctggc gctggagaga aaatttttga gttggttttt aactcgacgt ggacttctag
    28621 tccaatgact gtttcaaaat tcattcgtct ttccctccta aaatagctgg ttgttgttta
    28681 tggaattctg ttgcttgttc aaacgcatat gccgcttgat acatcgtttt ttcatcaaaa
    28741 taattaccga tgatctgcaa tccaactggt aatccttctg ataaacctgc cggtacagac
    28801 atacctggaa gtccagccaa gttgacaggg atcgttaaga tgtcactcat gtacattgtg
    28861 attggatcgt taatgttctc accgattccg aatgcaactg ttggtgaaga tggcccgatg
    28921 atcaagtcat aatctgcaaa gactttttca aaatctcgtt tgatcaatgt acggacttgt
    28981 cctgcttttt tgaagtaagc gtcataataa cccgcgctta aggagaatgt acctaacatg
    29041 atacggcgtt ttacttcttc accgaatcct tctgaacgtg agttgacata tacatcatct
    29101 aatgatttca cattttcaga gcgataaccg tagcggatac catcgaatcg ttgcaaattg
    29161 gaacttgctt ctgatgaggc aatgatataa taaacagcca caccgtattt tgaatgaggc
    29221 aagctgactt cttccacaac agcacctaat gaacggaatg tttctgctgc tttcaataca
    29281 gcttctttta cgccaggggc cacaccttcg cctaagtatt ctttaggtaa agcaatcttc
    29341 attcctttga tgtcgcctgt cagtccctct gcaaaatcag gaactgaaac gcctgaagaa
    29401 gtaccgtctt tttcgtcata accgctgata gctgtcaatg ctaatgcatt atctttcacc
    29461 gtacgggtca ttggtccgat ttggtcaaga gatgaagcaa aggcaatcaa accaaaacgt
    29521 gagacacggc cataagtagg tttcatccct acgatgccgt taaaagctgc tggttggcgg
    29581 atacttcccc cagtatcact acctaaagaa actggaattt gtccagctgc aactgctgct
    29641 gcagaaccac cagaagagcc accaggtact tttgttgggt cccaagcatt ttttgttttc
    29701 ttgaaataag aagtttctgt acttccaccc atagcaaatt catccatgtt tagcttacca
    29761 acagggatca tatctgcttg atagatttta tccatgaccg ttgcatcata aattggttca
    29821 aaattgtaaa ggatcttaga tgcagcggtt gtcaagatat cttttgttac gatattatcc
    29881 ttgataccaa ttggaatacc agcaaggacg ttgctttcat caatcccttt ttcatctaaa
    29941 gcttttgcct gttccaatgc tttttcttcg ttcaatgtaa tgaatgcctc gacctcaggc
    30001 tctgtttctt tgattcgttc aaatgttgtt tttgtcaaat cttgtacagt gatttctttc
    30061 gatacaagca tatgatgcag ttcttctaga gaacgattgt gtaattctgt cattatgcgc
    30121 cagcctcccc attatcgatg attgcgggta ctttgataaa gccgtcttct gtttccggca
    30181 catttttcaa taattcatcg cggttccatc cagcttgcgc ccgatcttgt cgcatcacgt
    30241 ttactgtttc aaccacattc gacgtaaatg gaacaccttc cgtatctact tcttccagca
    30301 tttcaaccat atcgatgatt ttacctaatt ggtcggtaaa acttgcaagt tcttcatctg
    30361 cgaacgcaag ttttgctaat ttggcaacgt gtttcacttg ttcttcacta atcgccatac
    30421 taccccttct ttctaaacga gttaaaaact ttgctctcta ttttaacaca agagtgccgt
    30481 gtctgaaatt gtttattgaa atttgtctga aaaaactcat ttttcattct tctactgagc
    30541 gacttttagc caatgcatct gccatttgat cttctgtcca aacttcgatt cctaattctt
    30601 gtgctttggt cagcttgctg ccagcatctt ctcctgctac cacgatatcc gtttttttcg
    30661 atacgctacc agtcactttc ccgccaagat tttcgatcgt ctcttttgct tcttcacgag
    30721 taaatcgtgt tagtttacca gtaaggacta ctgttttttc tttaaaagga gactcgactt
    30781 cttgcaattg ggcatttcga agccctttgt attcgaaatt gacgcctgct tgttttaatt
    30841 cattcatcaa ttcatggact tcttcgttac tgaaataagt gactacactg tcggcaatga
    30901 tatcaccgat cgtatcaagc gcaataatcg actcatagtc acttttactc aatgtttcta
    30961 gatcaccgaa atgttctgct aaaatttttg ctgctttcgc tccgacatgt cggattccta
    31021 acccgaaaat caaccgctcg accgaattat ctttgctgtt gtcgattgct gtcaaaatat
    31081 tatttgctga tttttctttt attttgtcca acgtcaataa ctcttcttct gtcaatttgt
    31141 aaagatcagc aacatctgct actagttttt tatcatacat ctgttctagt acgcgcggcc
    31201 ccaacccatc gatattcatc gcatttcttg aaacaaagtg gttcaaacct tctttcattt
    31261 gagcagggca tttaggattg atgcaccgta aggctacttc ttcatccaaa tggacaagtt
    31321 cacttccaca aactggacaa tgtgtaggca attggtattc ttcgctgtct ttaggtcgtt
    31381 tatctaacac gacttgcgaa acttctggga tgatgtctcc cgctttataa atcagaactg
    31441 tatctttcaa gcggatatcc ttcaacttaa tataatcacc gttatgcagg ctggcacggc
    31501 ttactgtcgt tcctgctact cggactggtg tcatgatagc tgttggcgtt actacccctg
    31561 ttcgaccgac tgtccattcg atgttttcga ttagcgtttc aacttcttct ggcggaaact
    31621 tgtaagctgc tgcccatctc ggtgctttga tagtaaaacc aagttgatct tgtagcgaga
    31681 attcattcac tttgatgacg attccatcga tttcataggg caaatccaca cgtttgtcat
    31741 gatattcttc aatgtatgac cacacttcat caatcgaatg acatagacgt ttttcccgat
    31801 tcgtgtggaa tccaattttt tctagctctt ctagcgcatc atactgggtt tttgcttgca
    31861 taggaccgaa atcagctact gtgtataaaa aagtgtccag atttcttttc gctgtgattt
    31921 tagaatctaa ctgacgcaaa gaaccagctg cggcgttccg aggattcgca aagatatctt
    31981 ttccctctgc ttctctgtct tggttcaatt ggacaaatga ccgttttggc atgaaacatt
    32041 cgcctcttac ttcgatgttc attggttctt ttaatttgat tgggaccgac cggacagttt
    32101 ttaggttttc agtgatgttt tctcctacag ttccatcccc gcgagtcgca cctctcacga
    32161 aatttccatc ttcataacgc aaagaaacgg aaagtccatc tatttttagt tcacagcaat
    32221 agtcaactac acgtcccact gctttttgta cacgttgatc aaaagctatc agctcttctt
    32281 tgctgaaaac gtcgttcaaa ctgtaaagcg gaatatcatg agtgactttt tcaaaacctt
    32341 ctaatacttt tccgcctact cgttgagtgg gagaatcaga cgtgatcaaa tcaggatatt
    32401 gttcctcgat tgctactaat tctgcgtatt ctttatcata aacatagtct tccactgttg
    32461 gtttatcttc tacgtagtat tcgcgagacc attggttcag tcttgtacga agttcttctg
    32521 ctcgtttagc agcttcgtca atcgtcattt catgttccat catttaccct ccactactaa
    32581 gctttttcaa ttggcgcaaa ggcagccaaa agacgtttta ctccttgact tgggaaagcc
    32641 acatctagtt ctagatcctt cgacgtcccg cttactcgga cgactgttcc tagaccccat
    32701 tttttgtgtt tgactttatc tccaggtttc cagctgttat tttcccctcc agtagcactt
    32761 ttagagggaa caaccgctgt ctctggctgt ttatagctat atgctgtttt tttagcgaat
    32821 acaggcgttt ttttaggcgt aggacgcatg ccttcgattt ccagtaactc ctgatcgatt
    32881 tcttctacaa aacgagaagg tcggttatat tgcgtccgtc catataatgt tctggagaaa
    32941 gcatttgtta aatacaacgc ttcttctgct cgcgtgatcc ccacatatgc gagacggcgt
    33001 tcttcctcca gttcgctttc ttccatcaat gctcgagata aaggaaaaac cccctcttct
    33061 agaccaatca ggaatacaac tggaaattct aatcctttgg ctgcatgcaa agtcatcaat
    33121 gtcacttggg aagcatcttc ttctaaattg tcaatgtcgg aaacaagtgc cagatcattt
    33181 aagaagaccg ttagtttttc ttctggtgca tcagcgtctt cttcattttg ctgttcgaat
    33241 tgtttgtcga attcttgtgt gaccgttaaa aattcctcca agttttcgat gcgtgcttgt
    33301 gcttctaatg tattttggat ttttaagtct tctagatatc cgctacgatc caaaacctct
    33361 ttcgtcaatt ctgtcactgt caagtatggg atcatctgag tgacttcttg gatcatctct
    33421 ccaaatgcac ctaattgctg tcctgctttt ccaccgatat ttgccagatc cacattttgc
    33481 gctgcttcaa gcagtggcca ttcatgaaga gaagcaaaac tgcgtagttt ttcgatagat
    33541 cctggtccga tgcctcgttt gggcgaatta acgatacgct caaaactgat tgaatcttga
    33601 ggatttacca gcacattcaa atacgctaaa atatctttga tttctttacg atcgtagaac
    33661 ttgtgccctc caaccatttt ataaggaata tttgctttca acagagtttc ttccattaca
    33721 cgagattgtg cgttcgtccg gtacaagatg gcaaagtcgc cgtaattccg atgattgctt
    33781 cgaatctctt cttgcatccg gtctacgata aaacgggttt cgtctcgttc attatctgca
    33841 cggtagtaag tgatcttgtt tccttctttg ttttctgtcc acaagttttt tggttttcga
    33901 ttgctattgt tttcaatgac ttggtttgct gcgctaagga tgtttttcgt ggagcgatag
    33961 ttttgttcta gcaaaattac tgcagcatct ggataatctt tttcaaaatc caagatgttc
    34021 tgcatatctg caccgcgcca gccgtaaata ctttgatctg catctcccac gacgcacagg
    34081 ttcctaaatc tacctgccaa taaattgact agcgtatact gtgcgtgatt tgtatcttgg
    34141 tactcatcta catgaatata atggaatttg ttttgataat acgtgagtga atcaggatgt
    34201 tcttcaaata atcgaatcgt attcatgatc aggtcgtcaa agtccataca ttgattatat
    34261 tgaagctctt tttggtaagc agcataacat tttgccgcaa tctcttcgta ataactgcct
    34321 tgcatttttg caaaatcctg aggggtctgc aggctgtttt ttgcttgaga gattgttcct
    34381 aatatacttc gaggatcata ttttttcgga tcaatgttca gttcttttag tatccgtttc
    34441 atcaaggtca gctgttcaga agaatcgatg attgtaaagt tccggttata cccgataaaa
    34501 tcaacatctc ttcttaaaat acgcacacac atcgagtgaa aagtcgatac ccagacatct
    34561 tcgcctccag atgcgagaat cgcattgaca cgttctttca tttcttttgc agccttattg
    34621 gtaaaagtaa tcgctaggat gttccaagga ttgacttctt tttcctcaat caaataggca
    34681 atgcggtgtg tcagcactct cgtctttcca cttcctgcac ctgccattag cagtaatggt
    34741 ccgtcagtgt gaagaacagc ttctttctga cgggggttca tcccgtttaa taattcagct
    34801 ttggatgaca ttaacaacat cctttctttt atcaatcttg ttaattatag cattttcttg
    34861 gctttcatta aactagctag ttcaaaatca tttgtttctt tttatggatt tttccttgtc
    34921 aattcgttga tttcgcgcta aattaaaaga aagcgaggcg tttgaatgga aaaaaaagga
    34981 aaaatcaaga aattagataa gactcagata tattttattc taaaaggaat atttgttgga
    35041 ctgctgacag gaatcgtcgt tagcctgttt cgattatcta tcgaaaagct aagcgattta
    35101 gttcgaagta tctatgaaat gagtcgggaa cagccgattt acttaattgg cctagctatt
    35161 tgctgcatcc ttgcagcatt tttcgtgggt tatctggtca aaaatgaacc ggatatcaag
    35221 ggaagcggga ttccacaagt agagggacag cttcgcgggg aattatcaat gaactggttc
    35281 tctgttttat ggaaaaagtt cattggcggt gtactttcag ttggtgcggg cctttttcta
    35341 ggtagagaag gaccttctat acagcttggc gcatccattg gacaaggagc tggacaattg
    35401 tttcggagtc catcttcaga agaaaagatt ttaatttcta gcggtgcaag tagcggactt
    35461 gcagcagcat tcaatgctcc tatcgcagga ttactctttg ttttagaaga aatccatcac
    35521 tccttttctc cacttgtttg gctgacatca tttgcttcag caatcactgc taacttcgtc
    35581 tctctttact ttttcggctt gagacctgtt ttatatctag gtgaccttcc ttctttgccg
    35641 ttgaaatatt atggttcctt agtgatctta ggagtacttc taggcatctt aggttttatt
    35701 tatcagaatg tcttgctggc tttgccaaaa ttttacaacc gattgccttt accagcttat
    35761 tttcacgggt tcgttccttt cttgctgatt ttgccaattg gttatttatg gcctagtact
    35821 ctaggcggag gcaatcaaat cgttttagct tttggacatg cttccttgcc aatcattatg
    35881 attatcggtt tgtttgttct tcgattcgtt ttttccatga tttcttacgg tgggggtctt
    35941 ccagggggga ttttccttcc gatattgaca ttgggggctt taatcggtag cttttatgga
    36001 aacattatgg ttgatttcgg gatggatcca atctacatca aggattttgt cgttattgcc
    36061 atggctggtt atttcacagc gattggaaaa gcaccgctga cagcaattat tttagtgaca
    36121 gaaatggttg gctctcttaa tcatctgatg cctttaggat tggctgctct tgttgcttat
    36181 atcgtcaatg accttctcgg cggtaatcca atttacgaat cattattgga acgtctactt
    36241 ggaaatactc agaccgcctc actaaaaggt gcaaggacaa cttttgattt tccagtaacg
    36301 gcagagagtt ctttagacgg attaatggta cgagacttca attggcctaa aaatatgctg
    36361 ctaatctcta tacgcagagg aaatcaggaa atcttgactc acggtgatac gatcatgaat
    36421 gtaggagata ttttggttat cttgactgat gaagcaaact tgccaagaat caagcaggaa
    36481 atcgaggcta aatcttctat cacaaatttg aagcaatcat tttaacgaac atggaaaaac
    36541 tattttacaa caactattca tctacactac ttgattctat atgattctat aaaaaagaag
    36601 aggctgggaa aacccagcct cttctttttt atttctatgc ttctgctact gcaggagctt
    36661 ttctcaataa accataaatc acaccagata cgactgctcc gatagcaata aacaccaaat
    36721 acatgaccgg gtgactcagt aagaatacaa cgaaaatccc gccgtgagga gccagtaatt
    36781 tgattccgaa agctccgact aatccgccag ttaaagcaga accaataata aaacttggaa
    36841 tggcacgaat cgggtcagct gctgcaaatg gaatcgatcc ttccgtgaca aacgatagtc
    36901 ccatcacgat gttcgtcaaa ccagcatctt gatctgtttt gctgaattta ttcttaaaca
    36961 aacgtgtagc aacgaaaatt gccaatggag gtaccattcc tccagccata acagaagcca
    37021 tcacgacact tccgccagtt gcaacagtcg tagctaaagt tgctgtacca aacacataag
    37081 cggctttgtt gattggaccg cctaaatctg ccgccatcat tccagctaat aatgcaccaa
    37141 gtaaagcagc attcgaacca ctcatacttg tcaagaaacc gttcaatgca tcattgattg
    37201 ctttcatagg gacattgacc agcaacatca agaaaccagt aatcagtaag ccaaacactg
    37261 gataaaagag gatcgtttta attccatcca atgattttgg taagttcttg aataatttac
    37321 gtaaaaatac gatgacataa ccagctaaga atccaccaat cagtgcacct aagaatcctg
    37381 caccgcctgt attagctaat gcaccagcag caaatccaac gatcaaacca gggcggtcac
    37441 cgatacttga agcaataaat cctgctaata ccggcagcat gaaaccaaat gcagcttgtc
    37501 cgatttggtt gaaccagcta gcagcttgat tgtaattccc tagatttgat aattgatcat
    37561 gtggcacgcc aataaattgg tcgatcatga aagaaagcgc aatagcgatt cctccaccaa
    37621 taacgaaagg taacatgtgt gatacgccgt tcatcaaatc tttgtaaatt ctttgtccga
    37681 tagtaccatc cgcatttcct tcttctgaac tgctttcttt tccatcacca tggaatactg
    37741 gtgcagtacc actaagggct agattgatca actcttctgg tttacggata ccatcactga
    37801 caggacgatt gatcagttct tttccgtcaa agcgattcat ctctactttt ttgtctgctg
    37861 caacgattac accttctgca cgggcgatgt cttcagcagt caatcggttt ttgattcctt
    37921 ctgaaccgtt cgtttcgact ttgatctcca cacccatttc tttcgctttt ttcttcaaag
    37981 catcttctgc catgtaagtg tgagcgatcc ctgttggaca agctgtaacg gcaacaacga
    38041 attttctttc tggatgagca gaagcttctg cagcttgtgt ttcttgttct gctttttctt
    38101 ctgcttcttt ttgctcttca gctgtttgga acaagtcttg gacttcttct ggtgtatttg
    38161 cttcttttaa ttttcctacg aaatctgcat caatcagcaa tcgagatagt gctgctaatg
    38221 cttgcaaatg tgtgtcgttt gcgccttctg gagctgcgat catgaaaaac agataagttg
    38281 gctgtccgtc taaggcttca taatctactc ctttttggct ttttgcgaat aaaactgttg
    38341 cttctttaac tgcactgttt ttcgcgtgag gcatggcgat tccatcacca agacctgtag
    38401 aagtttgtgc ttcgcgggct agaattcctt ctttatatgt ttcgatatcg gaaatccggc
    38461 cggcatcaaa cattttttgg accatttcat cgattgcgcc ttttttatca gtcgcttgca
    38521 aatccatgat catcgcttct ttgaccatta aatccttgat attcatgatt atcctccttg
    38581 aaactaatca atttttgtga tttcaacttc tggcagcaac tcatcaatca attcgcgagc
    38641 tgccaagtca tcagaaaaag ctgttgcgct tccgcaagca actccccatt taaaggcttc
    38701 gattggatct ttcgtacggc tgtaagcccc aataaagcca gcaatcattg aatcccctgc
    38761 acctactgaa tttttcaatg ggcgaactaa tacattcgtt ttataagttc cttgttccgt
    38821 gaagagcaaa gcaccgtctc cagccattga gatcagcaca ttctgtgccc cttcagctag
    38881 taattttttc ccatacggaa tgatttcttc tacagattgg aaggttgtgt tgtaaagctc
    38941 agctaattcg tgattgtttg gtttgatcaa caacggtttc ttaacaagtg cattttttag
    39001 gtcatcacct gttgtatcaa tcacgaaatc tgcacctttt tctcgaatga tatcaatcag
    39061 ttcttgataa aatccttttc gcaggctagc tggcgcgctt cctgacaata cgacgatatc
    39121 tccttgtcct actgttccta atgcttgctt caactcatcg atttcttcat ctgaaataga
    39181 tgggcctaag ccattgatct cagtttcagt gtctgatttt agtttgatat tgattcttgt
    39241 atcttctttt acggttgtga acaaagactg gatttgttct ttttcaagcc acttcgaaat
    39301 aaattcgcca gtgaaccctc ctaaaaaccc tagtgctgta gattgagaat cgatccgttt
    39361 caaaatacgg gaaacattga tcccttttcc tccaggtaac ttgaagtctt ccttcattcg
    39421 gttcaaatcg cctagtttta acccatctac gcgtacgata taatcaattg atggattaag
    39481 tgttactgtg taaatcattg tattgcctcc ttaattgttg tcttttcacg gaattcatta
    39541 acgaattcta atggacaacg ctcggttatg atcgtggctg cttccaaagg tgcaacagag
    39601 gtgaaggaca actggttgaa tttggtatga tcaatcaata caaatgtctc ttcggaattt
    39661 ttcatggcta aacgtttaac agctgcctct tctggatccg gagtcgtgaa tccttgttca
    39721 agatgggcac cgttcattcc cataaatgct ttattaaaat gaaaattttt tagttgttct
    39781 atcgcattag atcctaaaac agcattagtt gccagcttta tcgttccacc taaaataatg
    39841 gtagcaagct ccaaatcaac taaatttgcc gcatgttgaa cggaatttgt cactactgtg
    39901 atctgttttc cttgcagaaa aggaatcatt tctaacgtag tagagccagc gtctaaataa
    39961 atgacatctt cgtcattaat ggtttcagct gccgatttgg cgatttgctg tttttcgtga
    40021 acgtttttga gtgatttttc actcatattc tgctcaaaat tcaataattg ctctttctta
    40081 gctccgccat gaactctttc tagaaaccca ctattctcca gctcttgtaa atcacgtctt
    40141 atcgttgatt cagaagcatt caaaaggttt acaagatctt gtgatttcac gattttctgc
    40201 tgttcaagca agtctaggat tttttgtctg cgttcctctg taagcatttt cacgatcacc
    40261 tcaatacaaa taatagcata ttttttttct actagcaata taaatcagtc aaaaacgttc
    40321 ataaaagtta taaatcagtc aaaaaaaaaa ataaaaaacc agtcagaaag actggttttt
    40381 tatttttttg tctatcatca agccgtttta tcgtttttta ttttcgcttc ttgttttttt
    40441 catataaaca gaagcaggtt ttctttcctt atgaagaaga taataataaa gtcccatccc
    40501 gccaaacatg accaaaaaac cgatgactga tcgaatagga aaattaggaa caaaaaagag
    40561 acagacggat aataatgatg ccggaaccat tattcgataa tagagttgtt tatccatttt
    40621 cttcacctca tattttttgt aaagtaatca attgttctaa ttctcggtaa tctaaaaatt
    40681 gcacacgcag atgctgctca cctttcttga catcgaattg gatacttcgc cgctttttct
    40741 ttattcgttt gaaggtaaca tcagagagtc tatgtttgat ttcctttaac ggtaattctg
    40801 acagggattc tgaaggaaca tagattctta aggataaaag atactcttga tatttttcat
    40861 ctgttacctc tacttctaga tattccctaa tataataaca ataagcttcg attccattat
    40921 ccaaagcaac agtcggatcg ataactttat agcacatcat gcgtgatcga ttctcgtcaa
    40981 cccaaggaaa atacgcctga gcatttagtg ttccgcgaac acgcctttct ttataatctc
    41041 cttgttggat atcataactt tttgttacaa aaaatgaagc attcttttta ggaacaggtt
    41101 gcatttgtgc attctgatac tggacagatt ggatcgtatg gtcagtgtaa atgtattcaa
    41161 cgaatggcgg tttcaataaa ccgacaccat tgtcccaagc aagatgatca aacccaagct
    41221 ggtccctaaa ataggattga aacatttgat tgtttggctt ttgccagtta aaggggtctc
    41281 gataaagctg gatacatatg acttcgtttt ctaattcctt cactttttct acttgttgga
    41341 tgtcgagaaa aatcggttta gggatgattt gatgataata gcgactataa tacatttccc
    41401 aacacgaagt gaaacataaa ccttggtaaa aaagatcgta tcctggaaat tggttgcaat
    41461 cgactactac ttccccgttt tgttgtttca ttttaggtaa atgttcgatt tcatcctttt
    41521 tctcaaacaa tagccgttga gagatctgtt ttgtattgtg atagataaac tcgctataag
    41581 ctcgcatata ggcgaacacc ccatgagcaa tcattttttt ctgaatgaag tctcgaatca
    41641 aaaattgctt ttctttgaaa acagagatag acaatacatt ttttatcaat aattgattat
    41701 cttccaagcg aaaactacat tcgttctcgt catttcctac aactaaccaa ctttcgtctc
    41761 ttaccgatgc tagcattatt ttttcttgaa gctttcgaag atcatacgga tccgcttgtt
    41821 gtgtgaaaga gcggataaat gttggctgga tcaacagacg tgtcaaaata gcccaatcgc
    41881 ttatttcctg ttttttttct tcttcattta agtctgtgag ctggatagtc atcaataatt
    41941 tatcttcgcc aatcattttc tcacctcttt caaatctttt tataatttaa ttataaccaa
    42001 tgataaagaa aaactaaaac tttatgtctt agaaaccaat ttggacgatt acatgataga
    42061 ctaagtaaaa agaaacaaag aggtgtttac aatggggttg aaatttgaac gtacagataa
    42121 tttagataaa cttttcgaat catttgctgt cgatccggaa aaaacagttg caccaaaaga
    42181 agagatcgat cgatttctaa aaccacagcc acaaaatgaa aagaaaaaag acaagaaaca
    42241 aaagtaagtt aagctcaaaa aaagacttac cagccaaact tttatgaaag agtttgactg
    42301 gtaagtcttt tttattcttt ttatgattca attgcttgtt cgattgctgc ccacgcttct
    42361 tcttttccct gttttgtaac ggaagaaaag agaataaacg tgtcattgcg atcaaaatcc
    42421 aacgcttttt tgatttcgct ctcatgcttg ttccatttac cacgagggat cttatctgcc
    42481 ttagtggcaa caacaattac agggatatca taatacttca aaaattgata catctggata
    42541 tcttcttgag aaggcttatg acgcaaatct actaaagaaa cgaccgcacg tagctggtct
    42601 ctagtcgtta aatatgtctc gatcatcttt ccccattttg ctcgctcagt tttggatact
    42661 tttgcatacc catatcccgg aacatcgaca aaatgtaatg cgttctcgat caaataaaaa
    42721 ttcaatgtct gggtctttcc tggcttaccg gaagtacggg ctaaattctt tcgatcaatc
    42781 aatgtgttga taaaagaaga tttccctaca tttgatcgtc ctgccagagc tatttctggc
    42841 aattgtgtat ctggatattg ttttggtgcc actgcactta tgataatttc agcttgatgg
    42901 actttcatgg tctctctcct taacaaggtg atgaataaag caagcggctg tcgcaaaagc
    42961 caaaatgact tttacggcag cctcttttca tcaacccgct tttttctctg aatctttata
    43021 gattactgtt ggctcaccag acaattcagc tgcttctttt gtgataatca ctttttcgat
    43081 gttttcattt gaagggatat caaacatcac atccatcatg atttcttcaa tgatggaacg
    43141 aagtcctcga gcaccggtat tgcgttcgat tgcttttttc gcaatggctc tcaacgcttc
    43201 aggttcgaat tcaagttcgg tattatctag agaaagaagt ttttgatatt gtttgactag
    43261 cgcatttttc ggctcagtca agatccgtac cagatcatct gttgtcaatt tctctaaagc
    43321 tgccataaca ggtaatcgtc cgataaactc agggatcaat ccgaatttta gtaaatcttc
    43381 aggaatgata tgctgcatga cactttcgtc ttcagaaagt ttttggtttt gtgtaccaaa
    43441 tccaatcgtc ttttcgccca tacgattctt cacaatcgtt tcgatgccat caaatgcacc
    43501 acctacgatg aacaatatgt tcgtcgtatc aatctgaata aattcttgat gtggatgttt
    43561 acgtccgccc tgaggtggca cacttgcaac agttccttct agaattttca gcaaggcttg
    43621 ttggacacct tcgccggaaa cgtcacgagt aatagataca ttttcgcttt tacgcgcaat
    43681 tttatcgatc tcatcaatat agatgatccc tttttctgca agttccacat tgtaatcagc
    43741 agattgaagc aatttaagca aaatgttttc tacatcttcc cccacataac cagcttctgt
    43801 caaacttgtc gcatctgcga ttgcaaaagg tacattcaat gtttttgcta atgtttgtgc
    43861 taaaaatgtt ttaccagacc ctgtaggtcc gatcaagcag atattgcttt tttgcagttc
    43921 aacatcatct gtgttttctt gtgcttgctg attgacacgt ttatagtgat tgtatacggc
    43981 aacagctaac gagcgttttg cgcgatcttg tccaatcacg tagttattca atacttcaag
    44041 aatttctagt ggtttaggga cttcagtgaa ttcgcgtaca gcttcttcat aaaattcttc
    44101 atcaatgatt tctttacata ggtcgataca ttcattacag atgtagaccc ctggaccagc
    44161 tacgatcttt ttcacttctt cttgggtttt cccgcaaaaa gaacagcgta cggtctcatt
    44221 gctacttgga ttgtcataca tggtcttcac cccttaactt gcaaaaagta tgcaagaaac
    44281 tatcaaagac tttacagtct tttactatca taacatagtt tagtaaaaag aaaaagtgtt
    44341 taacaaagga tcaactgacc tatacctttg cattttttac tcttaacaaa aaataaggaa
    44401 ctgtgacaaa atcgtgtcac agtcccttat ttcgaataaa caattttcta gaagtagctt
    44461 cttcagaaat gatttattac ttgatttcta ttctttcgct tctgtcgctg tacctgtgat
    44521 caattcgatt gcttttttca ttgtcacatc atgttccagc atatcttctg tcaacacgcg
    44581 tttgatttgt tcgattggca tgttgtatgt ttctgataat tcttggattt ctgcattgat
    44641 ttcttcttct gttgcttgaa gattttcagc agctgcaatt gcttcgatca caagatttgt
    44701 tcttgtgcgc atttctgctt caccttcgaa ttgtttatgc aagtcttctt ctgtagaacc
    44761 agttaattga tagtacattt caggagagat accttgacgt tgcatgttgt tcaagaattc
    44821 gtccattgaa cgatgtactt catcatgaac catcacgtgt ggcaattcaa cgatttctgc
    44881 gttttcaaca gccatacgga tcgctgcttc atcttttgca tcgtccgctg ctttttcttt
    44941 tgtttctact aattctttgc gatatttttc tttcaattcg tctaatgttg atacttcgtc
    45001 atcaacatct tttgcgaatt cgtcatctaa ttcaggcact tcttttgctt ttacttcatg
    45061 gattgtcact ttgaagactg cttcttttcc agcaagatct tctgcttgat aatcttctgg
    45121 gaaagttaca tttacatcta gactttcacc tgatttatga ccaactaatt gatcttcaaa
    45181 acctggaatg aatgagcctg aacctaattc aagtgagtaa ttttcgcctt ttccgccatc
    45241 aaacgcttcg ccatctacaa agccttcgaa gtcgattact actgtatcgc cattttcagc
    45301 tgcagcatct tctttgataa ctaattcagc ttgtgcttct tgttcacgtt tgatacgtgc
    45361 atccacgtca gcatctgtta cttcacggtc ttgtttttca acaactagat ctttatattg
    45421 tcctaatttt acttctggtt tcactgttac ttcagcagtg attacccagt cttgaccttt
    45481 ttccatgctt tcaacatcga tttttggttg agaaacagga tcgatgccag cttctttgac
    45541 agcagcttca taagcttctg gtaatacagc attcaatgca tcttcatata aagcttcttc
    45601 accgtacata cggttgaata cttgacgaga aactttccct ttacggaatc caggtacgtt
    45661 caagcttttt ttcactttat taaacgcagt tgttaatcct ttttggattt cgtcttgcgc
    45721 aatcgtaaat tttaaaacac catcattcgt gccttttttt tcaaatgttg cagtcattta
    45781 attccctccg agtttagaaa ttcattttat acatcaaaaa cgtttcatgc atacctttaa
    45841 atagtacact aaccctttca aattgtaaac atattgaatg gatagaatcc ttgtttttca
    45901 taacattttt atctttttca ctgataaaat ctaatggaag aagatcattt gctgcaaaat
    45961 tttttctctt ttttttaaaa aatcttgttt ttcatcttct gtaccttcat acatcgtttt
    46021 tcctgtacac gcctctacag tcagttgaaa ccagcgcttc gggtcttcga tgtatgtatc
    46081 atagacagga taaacaattg cagattgcaa cgtgaattct tcttttaaca cggaactaag
    46141 cagcgcatct tcattcccgt aacgatctga aaatacacat aattgctggt aacttgcctg
    46201 ctgctgcggc tttggcagat cttttggtat gactttgact aacttttctt caatcgtcaa
    46261 atagaaaaca ggatggcatt cgttcaattg cctaagtgtc tccagtaatt ttgcccttgc
    46321 taaaatatgg acctctggcg atacaataag tttactcgct gtttggataa actcatgata
    46381 aggaagctgt tcgatctcat caatagacgc aagctgacgt gcaggttcca acgaaggaag
    46441 ttcctccgat ttattgtgga gtgccttgat cttctgcctc tccatttgtc cggataattc
    46501 ttctgcaaat tggatttttt caatgacccg ctgctcgaaa gcttcataaa aatctgtact
    46561 tgctatcaat tttctagcat ataaaaaatc ttgtgtactg attaacaagt caaaataaaa
    46621 ttcagcaaac tcctcatttt gaagatactg tttttcatgc aagagtgctt gcttcaatgc
    46681 ttcttttttc tcgtccaact cgtaaagaca aaaaacaagc aggctattag cctcaaagct
    46741 ttctttcaac tcgtaagctc gttgaaataa ttcttttgcc tgctgatatt gctggtttgc
    46801 tagtgcttgt tgtgccactc gcattaaatt ctcatatttt tctggaaaat caatcggctt
    46861 cacgcagtgt cctcctcttg ctcatattca gctcatgttc aatagtagca aaacaaaaaa
    46921 agcatgacaa ttaaaaataa ctgaagcacc ctctaaaagc tagattttag atctgacttt
    46981 tagaaggtgc tttcaactgt tactgctttt tattgctcat cagctgttga cttcctggtt
    47041 gaacgctttg atcagattga tcgtaacaac acttgtatta gtgaaaaaat cgcccagatg
    47101 ttgctttttc tgattaaaga ctgctggaag ataccctaac atcagcaaag gaaattttag
    47161 aatgaaccgg caagcacctt ctctaactaa aacggttgac cagctaagtt cttcttcatc
    47221 aaagctgatg actcgaatac caaagatcat tttcccaatc gtttggccat gattgaattt
    47281 cgtcaataaa ataaaatacg ctagataaat aagtaaggct gtgaatccgt agagactcag
    47341 ataagaatct gaaaaattaa gccaacctag atttttggca ataccaagtg ttaaacgcgt
    47401 aatagctccg atacacaaaa gatcgaccaa gaaggcaaac attcggataa aaaaacctgc
    47461 atagaaatac ttaggaaaat catttgcttt tggcggttca tttcttgtgt ccgtatactt
    47521 tttccattta cgttgtttct ttttgatttc ttcgggcgtc aaaggctctc tttcaaaaga
    47581 gctcagtacc ttttgggaaa agttggagtc aggtcctaca gcaggctgct gttgcttatc
    47641 tttttcttgt tccttatttt catttgaaag ctctgacatg cttactcacc tccgtaataa
    47701 tacattgctt ttggtgattc cgctgtccct agattctcaa gaacggataa gatctgacta
    47761 gtctcagaag gcttcaatcc ctggaattct gctagtttac ttcctaacca tgtactagca
    47821 aacccagatg gcgtggaaga atattctact agttccgcat cttcaagctg ttgttccttt
    47881 cgtatagctt ttaaagcatc ttcaggaaat cccaattcat cgactaaacc tacttctttt
    47941 gcttggacac catcataaat ccttccatca gcaatttttt tgacttcttc ttcagattta
    48001 ttccgtccct cgctgacgat tgctacaaaa cgactatatg cgctgtcgat atatgcttga
    48061 agcaccgctt cttcttcttt tgtctctggt cgcgttcctg aacccatatc tttcaacgct
    48121 ccgcttttaa ctgttgtatc ttccacaccc agtttttcta gaagtcctga ataattcaat
    48181 cctgacatga tcacaccaat tgagccggtc actgtttctt ctgttgcaaa gattttatct
    48241 gcttgagcag aaatatagta gccaccgcta gctgccatgt ttttcatgct gacatacatt
    48301 gggatatcat gttctttacg aatcgtatcc aatttcttag cgatttccgc actttcgtag
    48361 acaccgccac caggagaatt tacttctaaa aagatacctt tgactgttgg atcttcttca
    48421 atcgccttca gttgttccat aaaattttta tgattgtaac cttcagaagc aaataaacct
    48481 gaagaccctc ccgcagcaat cgttccatct actgataatt ttacgatttt ttgcgtactg
    48541 tctccctctt ccaacacatt tggagctagt tcttcatccc catataacca actgttcaat
    48601 ccctcaattt gatcgttttc ctgaggctta gtcaaactag ctgaaactaa cgaaaccaca
    48661 aataatcctg cagcaatcag aactgctgcc caacgtcttt tattcattct ttctcctttc
    48721 taatacaagt tttttatgac gatcacagtt tctgactgct cagaagtgtc gaaccgctct
    48781 gctttttctt cccgcgcata cccggaaaac gactcttttg ttaattcatc ttctaccgta
    48841 aactcacgag cttgagcaac ttccaaggca tcaggtgcga tttcttggat gctatcccag
    48901 ccagtatcta aaaatatttt cgtatcatct gatacaccag ctgatgcttc gaatttggac
    48961 aattgttttt ttaacattcc cagtgtcatg atctcaattt ttgaatccat ttttactcct
    49021 cctctatccg attactttct attgtaccga actcctgaaa aagatgatag ataaaaaccc
    49081 attatttttt gacataaaaa ggacatttga caaagaattt gatatatacc aatttatttt
    49141 ttattctttt tttgttgaca agaacattcg caaaaggtta tgattttaaa tgtttccaga
    49201 taaaaaacaa aaaggaggat agttatacct tttaggatag cgccaggtct gtgtaaacag
    49261 atgacgagga gagggtttat cgaaagattc ggcggatggc cctagggact gcactctaca
    49321 gaaaatccac aaaaaatgtc tgcaaagata aaacaaaagg attttcctgc agctggaagc
    49381 attcatacga attcattata gaaagtagga tgttttttat gtgcggaatt gttggaatga
    49441 ttggattaaa aaatgtaaca ccaggattga ttgacggtct agaaaaatta gaataccgtg
    49501 gttatgattc agctggtatc tttgtctcag atggcacaac tgattatctg gtcaaagcac
    49561 aaggcagaat tcaaaatttg aaaaacaaaa taaatattga tactacagga aatataggta
    49621 ttggtcatac acgatgggca actcacgggc aaccttctga agaaaacgcc catccacata
    49681 cttcccaaag tggacgcttc gtgctcgttc acaacggcgt aatcgaaaac tttgaagaac
    49741 ttaaaattgc ttatttagca aatgaccact ttattggtga gaccgatact gagattatcg
    49801 ctcatctaat tgaaactttc gcgaaggata ctacaacgca agaggcgttt ttaaaagctt
    49861 tgcgggtcat caaaggttct tacgctttcg ctttgattga tcggacagca cctgatgtta
    49921 tttacgtcgc taaaaataaa agtccactat taatcggact cggcgatgga ttcaatgtga
    49981 ttgccagcga tgcaatggct atgcttgctc atacgaagga attcgttgag attgaagatg
    50041 aagagatggt taccgtcaca tcagaaaaag ttattattca aaattttgca ggtgacatcg
    50101 tagaacgttc ttcattcgaa gcacaagtag atgcttcaga tatcgagaaa ggtacctatc
    50161 ctttttatat gctgaaagaa atcgacgaac agcctattat catgcgtcgt atcgctcaaa
    50221 aatacgtaac agaagacaat cgtgtctctc ttgatcaaaa gctggtcgat acattgtctg
    50281 atagcgatcg aatctatatc gttgcttgcg gaactagtta ccatgcgggg ttagcaggta
    50341 aacagacttt ggaaaaattg acacagattc ctgttgaggt tcatttagcc agtgaatttg
    50401 gctataacac acctcttctt tcaaaaaaac cattctttat tttcttgagt caaagtggcg
    50461 aaacagcaga cagccgccaa gtgctggtaa aaatcaaccg tctcggctac ccttcactta
    50521 cgattacaaa tgttgctggt tctactcttt cgcgggaagc atcctttaca ctgctattgc
    50581 atgctggacc cgaaatcgca gtagcatcaa cgaaagctta tactgcacaa atagctgtac
    50641 taactttatt agccaaagct atcggtgata aaaaagaatt tgaaacttct cttgtattcg
    50701 atatcactca tgaattgagt ttagttgcta atgcgatgga atcggtcatc gcccaaaaag
    50761 attatttaga agagttggca gaagtatatc tcagcgatac aagaaatgcc ttttacattg
    50821 gacgtggtgc tgactacaac gtttctcttg aagctgcttt gaaattgaaa gaaatcagtt
    50881 atatccaggc agaaggtttt gccgctggcg aattgaaaca tggaacgatt gctttgatcg
    50941 aagaaggaac accagtgatc ggaatcatca gtgaagaagt gactggtgcg catactcgag
    51001 gaaacctgaa agaagtcgaa agccgtggcg ctaaaacact agttattgtc tcagagggat
    51061 tagaaaagga aagtgaccag ctggtgctac caactgtcca cccttatcta actactctaa
    51121 ccacagtcgt accgactcaa ttacttgcat attacgcaac gctattacgg ggattcgacg
    51181 ttgacaaacc acgtaattta gcgaaatcag tgacagtaga ataataaaag aacaaggacc
    51241 agtgtcagac atctgacact ggtccttgtt cttttatttt ttatgaaaat atctcttaat
    51301 ccagtccgat ttcttctttg actactgccg cgattttatc gacatagtaa ttaactttct
    51361 catcagtagg cgcttctgcc atcactcgaa gtaatggttc tgtaccggaa ggacgaacta
    51421 ggattcttcc ttctgatccc atttcagctt ctgcctcttc aatcactttt ttgattgccg
    51481 gaacatccat cgcaccgttt ttatcactta cgcggatatt cactaatttt tgcggataga
    51541 ttgttacctc tgctgcaagc tctgataatt tcttacctgt ctgtttcatg atattcagta
    51601 actgaattcc tgaaagcatc ccatctccag ttgtgttaaa atctaagaaa atcatgtgcc
    51661 cagactgctc gccgccaaag ttataatcgt ttttgcgcat ttcttctaca acgtaacgat
    51721 caccaacttg tgtaacgaca tctttcaaac cgattccttc caccgctttg tggaatccta
    51781 agttactcat gacagtcgta acgatcgtat cttttttcaa tcgatttttt tctgccaagt
    51841 atttagcaca gataaacatg attttatcac cgtcgacaat gtttccaagt tcatccaccg
    51901 caataatacg atcgccatcg ccatcgaaag ctagtccagc atctgctcct ttttcaacga
    51961 ccatctcagc taaacgttct ggatgggtag agcctacgcc gtcattgata tttaacccgt
    52021 ctggatttgt gcccattgta taaaaatctg tttcaagatc ggcaaacaaa cgattaacac
    52081 ttgttgaagt tgctccgttt gctgcatcga cacaaatggt caaaccggaa aggtcaccgt
    52141 tgatcgtttg tacaaggaat tgagaatatt tcaataagcc ttctggaaat tcttctacag
    52201 ttcccaatcc ttcagctgat ggacgaggca attcatccac ttcagcatct aataatgctt
    52261 caatttctag ctcttggtca tctactagtt taaaaccatc tgcaccgaaa aatttgattc
    52321 cattatcttg tgctggatta tgagaagcag aaatcatgac ccctgcgctt gctttttgca
    52381 aacgtgtcag ataagcaaca cctggtgtag agatcacacc tagctggaac acttcgatac
    52441 ccaccgataa aagtcctgaa atcagcgctt cttctaacat ttgacctgag attcttgtat
    52501 cccgccctac taacacgcgt gggcgttttc cttcttcttc atgctggctt aggacataac
    52561 ctccgcaccg tcccagctta aatgcaagtt ctggcgtaag ttccttgttg gcttcaccgc
    52621 gtacgccgtc tgttccaaaa tatttaccca tagttgtaaa attactcctt taacttaatt
    52681 ttctgaggaa tttgttctgc tcatttgtgt tgattcgctt gtttctgatg tttcttctgt
    52741 acttgtggtc gagctgcttg tcccagattc cgaactggaa gaaatggttg ttgtcgatgg
    52801 ttccgttcct gaatcagcag atgaaatact tctactcgta cttgtatttt cttgtgtccg
    52861 actgctcgtc gaagcagagc tactgcttga cgtttgcaac acgggtgtaa tctccacact
    52921 aactgattcg ggcttgatac ttaacccctc ttctactggt atttcaattt tacgagttgt
    52981 tcgatgattg atacctgaga cattgatcgg tacagcaata ctgtcaccga tcgatgcaag
    53041 caaatcgcta gagccgctta cttctgcttc cagttttgaa aaactgaaat catagctttc
    53101 taccccggca gctggtgttc cttgctgtat cccataaagt cgtaccgact tgcttggctt
    53161 gatcgaatca gctctcactg ttacttgcac tggatcagag acgatactta atacttcccc
    53221 tgctgcattc agcgcctgta ttgggacctc actattaatc ccatcatctg tgaccatcga
    53281 agcgtccaca tcagctacta ctcgtttgat ttctgccaat gttttgtcac ctgtagtgat
    53341 agagactttt ttaggactaa cggaagtatc atcaagttca tatccagatg gtgtgaacgt
    53401 tgaaggaatc aacgtttcca catcgaaatc ttttattacc tttttctcaa ccgttactgt
    53461 aatagtcgat ggttcgatct ttgctgtgac agcactgctc aaattttgaa tttttagcgg
    53521 aacttcatgt gttccttcgc ccagcttagt gatatctgct gtgacgcgga acatccgtgt
    53581 atcttcgttt gcctctgcat tcaactgaac tcggtttgca ctggaaagtt tgacagtcac
    53641 tgcattttca tatccatgga tatagtagcg ctttgaatca taagaaatct tgatcggcac
    53701 ccccgtaact gtttgattat acgcttcatt tccagaaagc gtatttggaa cggactggcc
    53761 atttgcattg aagtacagcg caatactgaa cagcaatgca ataaaactgt aaagaatgct
    53821 tgtccgtttc tcttttgaga tcatttgcga tcccctccct tagtcatacc gtctaggaaa
    53881 gattgaatca cgtttttctt gttttttgtt ttctcttcag caattagttc tctacgcaag
    53941 attgccaaat attcttgctg ggataagcca gccatcagtt cattatctaa cgtgatgctg
    54001 acgtccccgg tttcttcaga gacaacgatg gtaatcgcgt cactgacttc gcttataccg
    54061 acagctgccc ggtgtcgagt cccgaattct ttagggatca acatactttc tgatagagga
    54121 agataggcgc ttgctactgc gatctttcct tcttttacaa taactgcacc gtcatgcagc
    54181 ggtgtattag gaataaagat attgatcagc agctccccag tgatatctgc atctaaagca
    54241 atccctgtct caatatactc atctaatcca gtatgacgtt cgatagtgat caacgcaccg
    54301 atttttcgct tggacatata ttggatggct ttgtcaaaag acaagatcat cttctcatct
    54361 tcctgctgtt cgctttttga ttgtttgaaa agcgaactgc gtccaagatg ttccagtcct
    54421 ctccggattt ccggctgaaa aatcacgata gcagctatca ccccgtacgt aatgacttgg
    54481 ttcatcagcc aagacaaggt gtgcagacca atgatttccg ctacgattcg gataacaata
    54541 aaaatagcta cacctttcag aagctgaatc gcttttgtgc ctcgcagcag ttggatcagt
    54601 ttgtatacaa gataccagac aaccagaata tcaagtatgt tcaccaaaaa attcagagag
    54661 aacaagtcac cggaaaacat ttgctgccaa tagtccaaat taaaaagttc cccgatttga
    54721 aatgacataa aaagcctctc ttctcttttg agatttcctc tctagtatat catatgtttt
    54781 aattttagag gctgatatgc tcgtattttt cttgagaaaa acgcataatt ttcaagaaaa
    54841 ttgcaagtat gcgttttatt tttctctgca ataaatattt ttaaacttca gagaattatt
    54901 cattatattt tttctgttat ttttcctttt tttcttttgt agcttgttcc atttttttac
    54961 gtcgttctgc tctggcagct cttctagcag ctcttctttc ttctgcttca aggtccgtcg
    55021 ttttttcttt tctagtctta acgggtacat cgatagattc ctctggttca agtcgtttct
    55081 tgatttt
//
LOCUS       DAKCAA010000011        52380 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000011 DAKCAA010000000
VERSION     DAKCAA010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 52380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.011"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            178..576
                     /locus_tag="OUE31_000778"
     CDS             178..576
                     /locus_tag="OUE31_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCU0221808.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            855..1355
                     /locus_tag="OUE31_000779"
     CDS             855..1355
                     /locus_tag="OUE31_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCU0221809.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(1438..1989)
                     /gene="lepB"
                     /locus_tag="OUE31_000780"
     CDS             complement(1438..1989)
                     /gene="lepB"
                     /locus_tag="OUE31_000780"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCU0221810.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(2141..2368)
                     /locus_tag="OUE31_000781"
     CDS             complement(2141..2368)
                     /locus_tag="OUE31_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HCU0221811.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(2365..2883)
                     /gene="msrA"
                     /locus_tag="OUE31_000782"
     CDS             complement(2365..2883)
                     /gene="msrA"
                     /locus_tag="OUE31_000782"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCU0221812.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(2903..3616)
                     /locus_tag="OUE31_000783"
     CDS             complement(2903..3616)
                     /locus_tag="OUE31_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HCU0221813.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(3619..4515)
                     /locus_tag="OUE31_000784"
     CDS             complement(3619..4515)
                     /locus_tag="OUE31_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCU0221814.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(4673..5515)
                     /locus_tag="OUE31_000785"
     CDS             complement(4673..5515)
                     /locus_tag="OUE31_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCU0221815.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            5647..6300
                     /locus_tag="OUE31_000786"
     CDS             5647..6300
                     /locus_tag="OUE31_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HCU0221816.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(6363..6890)
                     /locus_tag="OUE31_000787"
     CDS             complement(6363..6890)
                     /locus_tag="OUE31_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCU0221817.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6910..7857)
                     /locus_tag="OUE31_000788"
     CDS             complement(6910..7857)
                     /locus_tag="OUE31_000788"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HCU0221818.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(7869..9755)
                     /locus_tag="OUE31_000789"
     CDS             complement(7869..9755)
                     /locus_tag="OUE31_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCU0221819.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(9915..11993)
                     /locus_tag="OUE31_000790"
     CDS             complement(9915..11993)
                     /locus_tag="OUE31_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HCU0221820.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(12006..12281)
                     /locus_tag="OUE31_000791"
     CDS             complement(12006..12281)
                     /locus_tag="OUE31_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221821.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(12643..13098)
                     /locus_tag="OUE31_000792"
     CDS             complement(12643..13098)
                     /locus_tag="OUE31_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221822.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(13252..14460)
                     /locus_tag="OUE31_000793"
     CDS             complement(13252..14460)
                     /locus_tag="OUE31_000793"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HCU0221823.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(14572..14904)
                     /locus_tag="OUE31_000794"
     CDS             complement(14572..14904)
                     /locus_tag="OUE31_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCU0221824.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            15052..15927
                     /locus_tag="OUE31_000795"
     CDS             15052..15927
                     /locus_tag="OUE31_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCU0221825.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(16009..16590)
                     /locus_tag="OUE31_000796"
     CDS             complement(16009..16590)
                     /locus_tag="OUE31_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HCU0221826.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(16596..17855)
                     /locus_tag="OUE31_000797"
     CDS             complement(16596..17855)
                     /locus_tag="OUE31_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCU0221827.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(17857..18903)
                     /locus_tag="OUE31_000798"
     CDS             complement(17857..18903)
                     /locus_tag="OUE31_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221828.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(19138..19413)
                     /locus_tag="OUE31_000799"
     CDS             complement(19138..19413)
                     /locus_tag="OUE31_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HCU0221829.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(19656..20966)
                     /gene="der"
                     /locus_tag="OUE31_000800"
     CDS             complement(19656..20966)
                     /gene="der"
                     /locus_tag="OUE31_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HCU0221830.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(21148..22377)
                     /gene="rpsA"
                     /locus_tag="OUE31_000801"
     CDS             complement(21148..22377)
                     /gene="rpsA"
                     /locus_tag="OUE31_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HCU0221831.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(22512..23192)
                     /locus_tag="OUE31_000802"
     CDS             complement(22512..23192)
                     /locus_tag="OUE31_000802"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HCU0221832.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(23241..23876)
                     /locus_tag="OUE31_000803"
     CDS             complement(23241..23876)
                     /locus_tag="OUE31_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCU0221833.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(23942..25345)
                     /locus_tag="OUE31_000804"
     CDS             complement(23942..25345)
                     /locus_tag="OUE31_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HCU0221834.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGFLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVIHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(25332..26363)
                     /locus_tag="OUE31_000805"
     CDS             complement(25332..26363)
                     /locus_tag="OUE31_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0221835.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYERILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            26394..26615
                     /locus_tag="OUE31_000806"
     CDS             26394..26615
                     /locus_tag="OUE31_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HCU0221836.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(26780..27517)
                     /locus_tag="OUE31_000807"
     CDS             complement(26780..27517)
                     /locus_tag="OUE31_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCU0221837.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGNSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(27671..29011)
                     /locus_tag="OUE31_000808"
     CDS             complement(27671..29011)
                     /locus_tag="OUE31_000808"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HCU0221838.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(29248..30771)
                     /locus_tag="OUE31_000809"
     CDS             complement(29248..30771)
                     /locus_tag="OUE31_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HCU0221839.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(31149..31760)
                     /locus_tag="OUE31_000810"
     CDS             complement(31149..31760)
                     /locus_tag="OUE31_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCU0221840.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIP
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(31883..32007)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(32089..32805)
                     /locus_tag="OUE31_000811"
     CDS             complement(32089..32805)
                     /locus_tag="OUE31_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCU0221841.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(32811..33380)
                     /gene="scpB"
                     /locus_tag="OUE31_000812"
     CDS             complement(32811..33380)
                     /gene="scpB"
                     /locus_tag="OUE31_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HCU0221842.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISFEEDVSPDLFFDGMNKGE"
     gene            complement(33364..34161)
                     /locus_tag="OUE31_000813"
     CDS             complement(33364..34161)
                     /locus_tag="OUE31_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HCU0221843.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(34131..34502)
                     /locus_tag="OUE31_000814"
     CDS             complement(34131..34502)
                     /locus_tag="OUE31_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCU0221844.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGVYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(34521..35408)
                     /gene="xerD"
                     /locus_tag="OUE31_000815"
     CDS             complement(34521..35408)
                     /gene="xerD"
                     /locus_tag="OUE31_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HCU0221845.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(35504..35977)
                     /locus_tag="OUE31_000816"
     CDS             complement(35504..35977)
                     /locus_tag="OUE31_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCU0221846.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(36082..36945)
                     /locus_tag="OUE31_000817"
     CDS             complement(36082..36945)
                     /locus_tag="OUE31_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCU0221847.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(37141..39282)
                     /locus_tag="OUE31_000818"
     CDS             complement(37141..39282)
                     /locus_tag="OUE31_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCU0221848.1"
                     /translation="MMKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDA
                     AMQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIE
                     KNEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHRED
                     TKEEHAKELLKMISEKIAQENKVEPEHEAEKDTEKDISGVNAAGKESLKTNDLKTNDL
                     KTDIPEKTETLSEKQSEDEKSNGLPEADKKEMLEKADKKATESDGINNEADAETQSAS
                     EDSTALEAKIEKEENQPELIEAETEPITIVPNTEKTPQESNPEKKDLDKTQKKKSKKV
                     PYLALAAVLLLGGGGWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFI
                     RADMIHQDLSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDH
                     LADDIKLKADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVV
                     DSATRDQYKTAKEAVEKVKNTDLSAQLNEQLQQVDKMLTDKEKKEEEEKKKAEEAKKA
                     EKAKKAAEEQAKQAAQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARAS
                     DIADASNPAWTWAPGVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKS
                     ALMKGIGESALPFYIVTINCKTGWFGGNGSN"
     gene            complement(39499..40608)
                     /gene="rpoD"
                     /locus_tag="OUE31_000819"
     CDS             complement(39499..40608)
                     /gene="rpoD"
                     /locus_tag="OUE31_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HCU0221849.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(40632..42473)
                     /locus_tag="OUE31_000820"
     CDS             complement(40632..42473)
                     /locus_tag="OUE31_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HCU0221850.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(42655..44970)
                     /locus_tag="OUE31_000821"
     CDS             complement(42655..44970)
                     /locus_tag="OUE31_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCU0221851.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(45155..46015)
                     /locus_tag="OUE31_000822"
     CDS             complement(45155..46015)
                     /locus_tag="OUE31_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HCU0221852.1"
                     /translation="MEKRQKMENQKVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(46074..46706)
                     /locus_tag="OUE31_000823"
     CDS             complement(46074..46706)
                     /locus_tag="OUE31_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HCU0221853.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            46873..47634
                     /locus_tag="OUE31_000824"
     CDS             46873..47634
                     /locus_tag="OUE31_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCU0221854.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            47660..50251
                     /gene="mprF"
                     /locus_tag="OUE31_000825"
     CDS             47660..50251
                     /gene="mprF"
                     /locus_tag="OUE31_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCU0221855.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(50439..51626)
                     /gene="tuf"
                     /locus_tag="OUE31_000826"
     CDS             complement(50439..51626)
                     /gene="tuf"
                     /locus_tag="OUE31_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCU0221856.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            51994..52350
                     /locus_tag="OUE31_000827"
     CDS             51994..52350
                     /locus_tag="OUE31_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCU0221857.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT        14600 a        10924 c         8989 g        17867 t
ORIGIN      
        1 tataaagaaa ttccatctat tagttaagtg aaagtgaacc agtcctcatt ctatcacatc
       61 ttcacttttt tgatgatgca aatttttatt ttggtttcta tatatgaatc taaatttttg
      121 acagcgtttc ctaaataaga gatgatagac gaacaaaaca gaaaggagac gaaacaaatg
      181 aatagtatgg tttttgttaa ttttcctgtt gctgatgtca atcgttccgt tgctttttat
      241 gaaaagctgg gttttaaaaa aaatgaagaa ttttctactg aagaagctgg ttcaatggta
      301 tgggatgaca ctttttggat aatgcttctc tctcatgatt tttataaaaa atttataaaa
      361 gataaagaaa tagctgataa taaaaaaaca agtggtgctt tgatttcgtt tagtgttgaa
      421 aatgcggatg aagtaaaaaa atttgctcaa attgcaaaag aaaatggtgg tactttccac
      481 gaagtagata tgggaatgcc tgaagaagaa atgttttcat tagaagtcca agatctagac
      541 ggaaatacat tagaacccgt atggatgaag atgtaagcag ataactaatc tgacgttttt
      601 tataacaaaa aaacaaaggc ggatgatacg ataagtattc tccgcctcta ttttttttat
      661 tcgtacaatc tcttttttac agtttataaa agcagtcttc tcaccctttt tttaattgtt
      721 agatgccagt gtatgtaaat caccaatgtg tcatgacaca ttggtgattt tatggtatcc
      781 ttttattatt aactgacaaa ggagagaata ttttgaacac tttgattgca aaagacgttt
      841 ttagattgcc cgaaatgaat gcaagattgt tgtcgacctc tgctctttta ttagcccttg
      901 atgtcatctt atacaagata gcgattggtc ctgcttattt tcaaatcaca ttcggatttt
      961 taagtatggc gcttatgggt tatctatatg gaccgatctg ggctggtttg cttgaaatgt
     1021 tgtcgaacac tttaaatttc acgatatttg gttcaggaac gtttcaagct gcttttctta
     1081 tcacggcttt ccttggtgga tttattaatg gcttattttt atatcataaa aagataaacc
     1141 tgccttccgt catcgctgcc caattattga ttatgatccc agtcagcctt tttatcaatt
     1201 cttggctgat gtctgttttg tttggtgcag atttcaaagt aatttttcta ggtagattca
     1261 tcaggaatat gatccaaatc cctattcaaa taatggttgt ttattcattt atcaaaactt
     1321 tagaggctag aaaagtgttt aaacgagctg tttgatttta cgtactaagg tagtaaactg
     1381 attttggatt aaacaataaa gcgtgcagtc tcaacagact gcacgcttta ttgtttctca
     1441 ctggatccat tttatttcat caagtggata atagacaaat cttgctttac ctagaatatc
     1501 agttttattg atcgtgccaa acgaacgact atcttttgaa actcttcgat tatctccaag
     1561 tacaaaataa ttatcttccg gaagcttgga ttgtcccgtt agctcttgta gtgtaaagtc
     1621 cgtcgtatag gatgcatttg catgatctga tttcaggttt ttagttagat aaggttcctt
     1681 aactactttc ccattgatct tcaattgatc attttggtag ctgacatttt ctcctggaag
     1741 accgattact cgtttgatat aaatcgtgcc atctgctaat tgaaaaacaa caatatcaaa
     1801 tcgtctgatc tccgaaaatt tttccatcac aaccatatca ccttgcttca acacgttttc
     1861 cattgaattg ccttccactg gtaccgggat gaataaaaat ccccgcaaca tgaacgcaag
     1921 gaatacagaa acaagtaagt atttgaatac aagccagaag cgattaatat agcgttgttt
     1981 ttttgtcaat ctctatcaat ccatccctct ttttttcatt ctttctttat tataagaaaa
     2041 atatcaaaaa aatgcgacta gatagctgaa ataaaaataa ttctttcaat taggctattg
     2101 gacaaaaaac ttttttgatc ataaagtaca aaactatctc ttatatgtca tgattatttt
     2161 ctaaatattt ttcccatgct tcgtcaaaga tatccatgga cggcaaatag tcgacattca
     2221 gttccagata attagaaatt tcttcgtagc tagagctgtg cttaggaaat tggatgtctt
     2281 taccggcttc tgtagcgaaa acagataaag catcatgtgt gccaccgcct cgcagtgtca
     2341 ttaaataatg aaaaaagctt cgattcaccc ttcgttcctc caattttctt cgataaaggc
     2401 agcccggcgt gcatggtttc ttttaaaatt ttcaggatgc tttttataat actcttgatg
     2461 gtcttcttct gctagataaa atggttgggc tggttcgatt tttgtaacga ttggctgttc
     2521 gaaacgtcca ctttcagcta actgtttctt acttttttca gcaatgatcc gctgttcttc
     2581 tgtcaaataa aagatcaccg ggcgataatt gtcaccgcga tcctcgaatt gtccgaaagc
     2641 gtcagttgga tcagtttgct gccagtaaag ttctactaat tgttcatatg aaatcaatgt
     2701 tggatcatag ataatctcca ctgcttctgt atgtccagtc gtttggcttt ttacttgttc
     2761 ataagtcgga tctggtacat gccctccagt atatcctgac atcactgtat ggataccagg
     2821 aagcgtgtcg aaaggctgga tcatacacca gaagcagcct cctgcaaata ttgctcgttc
     2881 cattatgatt ccccctctaa tactactcat ccgatgattt tttattttct tttgtcttgc
     2941 tttcagtact gctggtgcta gttttgttgg tatttgagtt gtttgaagca tcagaggtat
     3001 cttttggcaa atatagacta aaccgaatgt catcatttac taagtcgatt ttatctgctt
     3061 taatatacat cccgttttgc attcggaatt gatccaacct aagcatgata gtcagatcat
     3121 ctgtattgac ttcgatccaa tctggtaatt tatagtttct cttgatcata ttcatcacat
     3181 ctttgattgg caaactcaat gttccgatag aaagacttct agcttttagt tggacatttc
     3241 cgttttccat cacatacgga tcaaaatata aatagaaatc gataggaaaa cctagtactt
     3301 cgaaagtacc attgagtagt gcttcatttt ccaaataaaa tttatattca atatcactat
     3361 ctttttgata ctcactaagg aaaaagctga tgatttgatt gactttttct ttatttgaat
     3421 tgatcgttaa gacaggatct ccttgtcttt ccgtaagagc tggtatttct gggagttctg
     3481 gttcccgatt agcaaaaata cggctgccta aaaatacggt cgaaccaagt actaccccaa
     3541 gaaggataag gaaggcgaat ttccagtaat ttgttttctt tgttttgttt gaagatacgt
     3601 cagatcttgt tttcatgttt attgatcatc ctccttctct aaccattggt tttgtgtctc
     3661 gatcagctga tctctcactg catttgccat caattgataa cctaaattat ttggatggaa
     3721 atgatcttct tcatagagca cattattttt gatgccattt agattttctg tcgtgctagt
     3781 tgtttgatct gttccttctt ctgtgacacc tacttcctga ttcaatcctt gataaagcaa
     3841 atcattgatt gggataaagt agcagttcgg catttttttt gtcaccgttt ctgttccttt
     3901 gttccaattg ttaacaattg tctgcatgtc agtgatctca ggaaagttca aataaaatgg
     3961 attgtagatg cctaaaatgt aaataggtgc ggttttattg agggatcgaa attcttccaa
     4021 tagttctgtg acattttcct gatagttttt cagtggcttt ttaaaggaat tgaccgttaa
     4081 cccgaataaa ttattttgga taactttcat caaatcatta ccgccaacag tcagtgtgat
     4141 aaaatcagct gttttgatat tgtttcgaat ttcttctttt gtttttactc gctttaagat
     4201 ctggtcactt cgttcaccat ttacaccata gttttctgtt tcaaccgcgg tcaaattata
     4261 acggtctttt agatcatttg cgacaagggg aacgaatcct ccttgcttgg tttgatctcc
     4321 tactccttca gtcagcgaat ctccgatagc tatgtagtga agtttttctt ttttatttgg
     4381 atcttctctc acagtagtta ctggtttcat tagtgggcca gctttcggta tagaagcagc
     4441 taaacctgca tagatgatga tcgcaattaa taatgggaac aaaacgagga tcaaatgtcg
     4501 tttcgttaat ttcatttttt cacctcttgt attcgattgg ttctaatgtt atcaaaaatt
     4561 ttatcaaaaa ggtagtcttt atgaaaaaag aaaacaatta ttttcctaat tttataaaga
     4621 aaaagagaat aagctgcaag cctttcaggc tgagggctta tcctcttttc gactaatcta
     4681 cataatacat gattgcaaac gcgtctttac cagtatgcgt agcgataacc ggattcgtat
     4741 gcagtacagg gatatgcatg tccgggaata attcttgcaa accctctttg aattcttgcg
     4801 ccaattcttt tgcatccgca tgtgaaatac cgatttgtcg cacatttggc aattctttca
     4861 gttcattttt caaattatta aaccatttat cgaacgtttt ctttcctcgc cccttagtta
     4921 cagggattaa ttcagaatgg gcgaaattca tcaccacgcg tatgttcaaa acactagaca
     4981 gcaaaccagt tgttcggctg attcttccac cttttaccaa gttatctagt gtggatattc
     5041 cgatgtataa ttttgtattg tcttgtactt ttttgacttc ttcaaggatt ttctctactg
     5101 ttttaccttc ttttgctaat tcagctgctc gaattacctg aaaagataat ccttggtcag
     5161 tggtatcact gtcgataacc gttactttcg tttttgttag attactggct tgtcttgctg
     5221 cttctactgt tccactcaag ccttttgtca tatggatcga aatcacttca ctgccgtctt
     5281 ctcctagctc atcatacatc gagatgaatt ctccaattgg tggttggctt gttttgggca
     5341 gattttttgc tttcgccatc atttccataa atctttcgcc gtctagttgg tcatcatcgg
     5401 gatatactgt tccgtcgatc atgatggata gcggcatgac acgaatgcct aaagcatcgc
     5461 gtacattttt ttccatcgta catgaagaat ctgttacgat ttttacattt gtcattattt
     5521 tctctctctc tttctttaac aagatgcctt attcatgtta aactacatgt aagacaattt
     5581 ctatttttag tataacagac aaataatgat ttttcattaa ttacacctag taaaggagcc
     5641 gttttcatgg aaaaaacgaa atttaatcga acgtatgaaa tattaaatga agtgtttaat
     5701 gcagtcaccc atggaattgg gactggattg agtatcgcgg gactagtggt tcttttagta
     5761 aaaggtgccc acttgcattc ctccctccat attgtctctt atgctatcta tggatcgatg
     5821 atgattcttt tatttttaac gtctactttg tttcattcat tgatttttac aaaagcaaaa
     5881 aaggtgttcc aagtattcga tcatagttcg atttttcttt tgattgcagg aagttatact
     5941 cctttttgtt tgctgagtat ccgaggatgg ctaggttgga ctttatttgt attaatctgg
     6001 ttgtttgcga ttcttggcat tatatataaa gcgttgacgt tgcataaacg ggagagagta
     6061 tcaaaagtat ctacgatcat ctatattttt atggggtggc tctgtgtcgt ggctgctgtt
     6121 cctctttatc actctcttgg aatgactggt gttattttga tggtagcagg cgggctttct
     6181 tacacgatag gcgcattctt ttatagcttg aattctatcc gctatatgca tgttgtttgg
     6241 catttgtttg ttatgttagg tgcaggtttt atgtacttct ctgttttatt ctttacttaa
     6301 taaaaaaaat aaagctatgg atgggacagc tctaaataac agctagtcta tccatagctt
     6361 ttttatatcg tcaattcgcc tgtcccgctt tttacaggat tctcattacg ctgatacgtt
     6421 tcaaattgat gcggataacg atttttttca tccatttctc cttgactagt attgatcagt
     6481 gaccaatcag accagtcaac aggtggaaaa taagcatctc catcgaatac atgatggatg
     6541 actgtacggt ataatatcgt acaaaatggc agaaattctt gataaacagc tgaccctcca
     6601 gcgatgaaaa agataccgtc tgtttctttt tccagagcaa gcacgtcttc cacactatgc
     6661 atgacatgca cgccttctgc tttataggaa gaatctctcg tcaaaacaat cgtctgacga
     6721 ttcggcaacg gacggctacc catcccttcg aatgtttttc gtcccatcac tagtgtattt
     6781 gcttctgtca tttgtttgaa gaatttcaga tcatttggca aacgccaagg aagacggtct
     6841 tcttttccaa tcaatccgtt ttcatcctgt gcccaaattg cagctaacat tttctcatcc
     6901 tttctgattc taaacagcga taggagcttt gatcgccgga tgtgggtcat atccttctaa
     6961 ttggatatct tccatctcaa aatcaaatac tgactgcttt tcctgattca aaactaaagt
     7021 cggaaatgcg cgtatttctc ggctcaattg ttctttcatt tgttcgatat gattgatata
     7081 aagatgagca tctcctaatg tgtgaacaaa ttcgccaacc gctaaacctg tttcatgtgc
     7141 aattaggtga gtcagcaacg cataacttgc aatgttgaac ggaacgccta gaaacacatc
     7201 cccactgcgt tgatacaatt ggcagcttag ccgtccctct tgaacataaa attgaaacat
     7261 cgtatgacaa ggaggcaaag ccatgctagg aacatcttcc ggattccatg cagaaacgat
     7321 caatcttcta gaatcaggag tctttttgat tgcttcgatc acttgtttga tttgatcgat
     7381 aaagccaccg tcttttgttt cccagtgacg ccattgatag ccgtagatgt gtccaagatc
     7441 gccgtatgtt tcagcaaagg aatcatcggt taggatcttc tcgcaaaaaa gcttgctctg
     7501 ctttttatat tcttcattga attcaggatc tgtcaaacat ctatggccaa aatcagtcat
     7561 atctggtcca ttatagtctg gacttttgat gtagcgttca aatgcccatt catcccaaat
     7621 atggttttta ttttgtaata gatagcggat attcgtatct ccttttaaaa accaaagcaa
     7681 ttcgcttttg atcaatccaa aaggtactcg tttcgttgtt aacaaaggaa accctttttg
     7741 cagatcaaac cgcatttggt atccgaataa gcttaatgtg cctgtgcctg ttctgtcttc
     7801 tttacgatgc ccttcttcca acaattttct tcctaagtca agatacgctt gttccatcct
     7861 ttttcctcct aatcttctac ccattcactc aagtattccc accgtgccat tttttcttca
     7921 agttgtgctt ctgtttcaga tacgtcgttt tgcaattctt gtaatcgagt gaaattatct
     7981 ccttgatgat tcatctcttc ttggagcaat gagatttttt cttcaagttc tgcaatctca
     8041 tcttcaatcg tttcccattc tttttgttcc atgtaagata atttcttctt ttcagcaggt
     8101 tccttgctct gtatttttgg tttcgctttt tcagcaggct gctgggtctc tttttgcttc
     8161 agtaaataac tggacatgtt tccgtaataa agttcttgtt ttccgtttcc ttggaatact
     8221 aataacttat ctgctacctt gtccaagaaa taacggtcat gggaaacagt gatcacagca
     8281 cctggaaaac ttctaaaata atcttccaaa atcgtcaatg ttgctatgtc caaatcattg
     8341 gtcggttcat ccaataataa aacattaggt tgctgaatca gcagtttcaa caaaaataac
     8401 cggcgttttt ctccgcctga aagtttgcct atcagtgtcc catgcataaa tcttggaaat
     8461 aaaaatcgtt caagtaattc tgctactccg atttgactgc catctgctgt ttttgcttct
     8521 tcagcagctt cttgtaagta agcaatcatc cgtttatctg gtgccatttc ttcattttct
     8581 tgtgtataat acgcaagatg aaccgtttca ccgatagaca ttgtaccgct atccagggga
     8641 attctgccag ctagaatatt aagcaatgtc gattttcccg caccattttt accagtaata
     8701 cctagtcttt cccgagattg aatcaataaa tctaaatgtt ctagcagtgt ttggtcattt
     8761 atacggtaac tgccatcttt gatttccagt acttttttcc ctaaacgttg tgtcgctagg
     8821 ttcagctcta aatcatcttc ttggtttact tggtacaagt tctcctttag atcttcgaaa
     8881 cggttgatcc gtgcttgctg cttggtgcca cgtgcctgta cgccagccct catccaagct
     8941 aattcctgtt tataaagccg cttgcgcttt tcttcttgtt ctacttctac acgatcacgt
     9001 tctgcttttt ctaagacgta agcttcataa tttcctttat actcgtataa ttttccaaat
     9061 gaaagttcga agattcggtt tgctactcta tctagaaaat aacgatcgtg ggtaaccatc
     9121 aatagtgcgc cacggtattg tttcaaatag ttttccaacc actcgatcgc ttcataatct
     9181 aaatggtttg ttggttcgtc tagtaatagt aaatcgggtt catcaatcaa cacttgcgcc
     9241 agactaactc gttttttctg accacctgat aaagtactga tttttttatc taattcactg
     9301 attcctaatt tttgcaaaat aatctttgcg ttggtatctg tagtccaagc atcttcttta
     9361 ttcatttgtt cttctgcttt agcataacgt ttttgcacat cagggtcttc tccgttttcc
     9421 cctagttcga tcaatgcttc ctcatatgct cgaacagttt ggatcaaggg gctgtttcct
     9481 tgaaagactg cttggagaac agttaattca tcggaaaatt cagctgcttg agaaagataa
     9541 ccaatacggt aatcagttgg ataaaacact gtttgccgat caccgtcgct gctatcgata
     9601 ccggcaataa tatttaagag acttgtttta cccgtcccgt tcgtcccaat caacccgata
     9661 cggtcttttt cgtggaccaa aaaagaaatc tggtcaaaca aatctttttc accataagtt
     9721 tttttgaggt cagttacttt taattctttc aacatgttcc ctccttatct tggatattgt
     9781 atcataaaaa tagtgaactt caggaaaatt tttttggtat ttgttctttt tgtgttctca
     9841 aaaaaagaac aggaccgatt cgatcctgtt ctgatatgtt ttgtttttta taaaacttga
     9901 aaatttttac ctttttattt tattggactc gttttttttg actttgctcg aaacgcaaat
     9961 cggaaagaaa agttatcaga tggtttgttc atcgtataag attctaacaa attgatattc
    10021 ctgcgatagc tgttcgcaga aaacgtcgtg attttttcag caacttcgta ttcatcaatg
    10081 atttttcttt caagataata acctcttagc atttttttcg taaacagact atcttgctgg
    10141 atcatccacg aagaaatcaa attccccgag ttcattttta ttccttcaag tttgcgttgc
    10201 tggataaaaa attgaaccat cgtttcatca taaatatcag tcaagttatc taaactttca
    10261 ataatcaact gagtattttt ttgatatgtc tctctgattt cttggatatc ttcatcacta
    10321 ataaatgtct gacgatcagc atatcttctt tgccaaaaca ttttcggatg gagaacgatt
    10381 cgcattaacc tacggacaac aatgaaccaa aagccgataa aagacaaaat ctggcttgtg
    10441 atagaatgtt cgaatcgaga aagaaaacgg gagtaaaaac gataaccatt agaagaaagc
    10501 ttgcccgaac gataactttc atccaatcca tcccgttcga tcgacaaaat cagtgcttgt
    10561 atttcttgta cttcttgctt ttcatcatcg gttaaatctt ccaagtacag atcacgtatc
    10621 cgttcttgat aattttctat cactgcttca gtggctaaaa attcttttgt attacgatca
    10681 atttccttta tttcttttcg caaaacttca acgacctctt ctaaaatcat caaagcattc
    10741 aaatccgtgc ttttcgcttc ctctgtttcc gtcagcatag gcaagacaat gatccctatg
    10801 accaaagtca ctaagatgac acccgccgtc agaaacaaaa gcaaagaccg ctggtaaaac
    10861 atcatattat tgattgaaaa tggcaaaata aaaatcgtag ccaaactgac tgttcccttt
    10921 acaccgccaa atgttaagat caagatctcg ttcaactgtt ttttgaactt tttactgcca
    10981 tctttgaata cataaaaaag actgatagaa atgaatctga tcacaaaaag catgacagag
    11041 attaatacga taatcgctaa taaaagaccg tttggatata aaccgtctcc ccatactggc
    11101 gagaacactt gcgtcaattc gattcctaaa aatataaata ctaatgcatt cagtgtaaaa
    11161 gcaatagttg tccatgtact gtgggacaag ctcgacaatt ctgcatcaaa cacagagatt
    11221 ttcctaaaac cagaagcttg gagaatacct gctgccactg cagcaatgat tccagataca
    11281 tcaaatgcct ctgccaatac ataggctaga aaaggaagca aaagttcgat cagcagatac
    11341 cctgtgacat cttgtgctga tgctttttcg atcaaatgaa ttattttttg tttgaaccag
    11401 acaagcaaaa agccgatcaa agctccccca atactagaaa ctactagact catccccgcg
    11461 tttactgctg aaaaagatcc ggtgatcagc gcaccaagag caaactggaa ggcagtaaca
    11521 ccagatgcat cattcaaaag accttctcct tccaaaatat gcatcgcctt tttagggata
    11581 ttcactcgtc cagaaagaga actgactgct accgcatctg tcggacctaa cgctgctcca
    11641 aaagcaaagc aggcagcaag tgggacactt ggcaacagga atgataacgt cgcacctacc
    11701 ccgacaaggg tcaaaatgac tcctccaaat gccaagaaca aaattgtccc gaaatttttg
    11761 agaatcgaag aaatatctgc tttttctcct tctctaaata acaatggtgc aataatcata
    11821 actaagaaca attcaggttc aaaatcgatt gattgtcccc actctgtcag acctaatacc
    11881 actccaagga aaatttggat cagtggagct ggaatcattg gcaaaatgcg gctagctatg
    11941 ttcgataagg tgatcgttac tgcaaataca ataactaact cagcaaattc catcgtccat
    12001 cccctttatt ttttattttg tgtaagcatt tttaaaaatt gttctttttt ctttaaaatt
    12061 ttggtttcga ctacttcaac ctgtgtttgg ttcccctcta attcacactg tacacgtttt
    12121 gactccaaac gaagcagatc atgtttcaga cgttccaact gacgatacat caatatattt
    12181 cttttacgca acttacaaag tatttgacgg cggtcatcca tcgaaagggc gccatagcga
    12241 tcatgcaaca gttttttttg ttgttcaaaa ctctctctca ttttccagat ctcctataca
    12301 caaacttcca tcattatagc aaagttcttt ttggatgaaa aatatttcat tgtttcatcg
    12361 tttattgcta gttagaaatt tccataaatt tttcaacgcc tcattctatt ccaaatagta
    12421 tcagatatca agtaaaactt aagaaagata aaagtttctg acaaaaggat gtttactttc
    12481 ccattcctgc ctttcttgtt cttttatcac aacaaaaaaa tggggctgcg acaaaaatct
    12541 tgtcacagtc ccttattctg aataaacggt gtggaagaga cagcctatca gtagtaataa
    12601 gacacatctc tttcacagcc tcatttttgc gtaaaaatcg atttattcga aaaattcccc
    12661 gtatacatct tctacacgtt gatctggatt gatcacgata tacaagttac ctgttttttc
    12721 gctgattttt gttgattgat attgattgtc taatccttct gttcctttat ctagatatgg
    12781 gaagtacaca agatcaggtg tgccatttcg gtaaaggatt tccattcgct cgatatcttc
    12841 gtatttcaat gcgcgattaa acatgcccat ttccagtccg cctaggttga tatcatgtgt
    12901 cgcaactgcg tccccttcat ggaagatttc gattttaaat ccagcacacg gatggatttc
    12961 aacaaattca ctgccattga ttcgtccaaa acttgttgtg atttgtttga tccaaagatc
    13021 gccgatatga cggcggttga tcgtccaggt ttctccattt ctaaaataaa attttagcgc
    13081 tgtcatttct ttactcatta aaaagactcc tttatgatgt aatttattct tgtactacct
    13141 cagtttagca caaatttatg taagtggtca catcttatgt tttttcttct aatgacgtat
    13201 ctgcccactt taagtagcca acaaagctga gcagatacag tctagtgttt tttaaatcaa
    13261 tttttctttc gataaaaaat ccaaaacctg ttttttatca ttttttattc tttgttctac
    13321 gacggctttt tcagctaatt gcaaagcttc actaacccac ttaccaggtt tttttccagt
    13381 ttcttctagc aagattttac catctactgc taattcgctt aatgacttga taggtaaacg
    13441 atcataggat tctcctacgg catccatctg aggtgtttcg tcaaaataga tcatcaattc
    13501 ttctacttgc agtgcatgtt ttttgcctaa gaagtacaat tcgaatggtt ccaaagctcc
    13561 agtttctcgt tgtcgtagtc cttggacaag tgcttgaacg tctttaatca tttggttaga
    13621 acacttccac gatttcaaaa aggaacgaat ctcattttct tttagatcca gttggctgat
    13681 caataatgcc catgcttggc tctcttcttt caatgggacg gatggtaatt cagcaaaacg
    13741 taaaagtgct tcgccttctt ctttcaaacc gggacagcaa atgtagcact ctgtttcaat
    13801 aaatgcatgg attcccgcgg cccgttcatt tcccaagagc atcttgatga attccacatt
    13861 tatacgttct acagatattt tacctaatag ctcgtggttt tctttgatgg cgtagaaggt
    13921 ttcttcctct aatttgaacc ctagttgact gacaaaacgc aacccgcgca tcattcgtaa
    13981 ggcatcttca tggaaccgct catgaggatt gcctacagct cgcaagatct gttcttctag
    14041 atcttgcaga ccatcgaaca aatcgatgat ttctccatct tctttcaaag caaacgcatt
    14101 gatcgtaaaa tctcttcttt tcaaatcttc tgccaacgaa cgaacgaatt cgacatgatc
    14161 tggtctacgg tagtcctgat aagttgattc cgtccgaaat gtggtgatct catattgttc
    14221 atcattttct aataccaaca cagttccatg ttcgatccca atatctatcg tttttggaaa
    14281 aagctgtttg atttcttctg gaaatgcgct tgttgcgata tccacatcat ggattggctg
    14341 gttcagcaag atatcacgaa cacttccacc tacaaaataa gcttcatatc ctgcattctc
    14401 taattttttc agaactggaa ttgccttttg gtattccaga ggtaattgtt ttaatttcat
    14461 ttttccaacc tttcctgcgt gtttcttgtc ctgagataaa gactcagttg catggtgact
    14521 gtttgacaag tccgtttcag agtcttcaag gccaggacca cttcatcttg tttactcgtc
    14581 cttacgctca aagcgattat ggtctctttg attgaatttt tccatgtttt tttcaaaaac
    14641 ttcagttaag tcgatattca atgaattagc catgatcatc gtaacgaata aaacatcacc
    14701 aagttcttct gctaccgagt taactggttc agaagccttt ttgctttttt ctccataagt
    14761 gtggttgact tctcttgcca attcacctac ttcttcagtt aatcgagcca tctgagctaa
    14821 tggagagaaa taccccacct tgaattgctg gatatattca tccacttcct gctgcatact
    14881 gtataaagaa cgctttttat ccatcttttt ccctccaaaa ctatcttacc aaaactttaa
    14941 cgcaaatcct agataagagc aattgagaaa atcgaatttc catgctacat ttaggaagga
    15001 atttctaaat ggaaattctg tgaaaataca taattgaaag ctggaattca tatggtcaaa
    15061 cgaaaaacag taaaagaagt tctttttatc attataggaa caagtattta tgcatttggt
    15121 cttgtttact tgaacatcgc taatcattta gcagaagggg gagtctcagg gatcaccttg
    15181 atcttaagag ctttatttgg tattgatcca gcttatacga ctttattaat caacatccca
    15241 ttgattttac taggaggaaa gatcctcggt aaacgttcct tggcctatac tgttctaggt
    15301 acactttctt tgtcattctt tttatggatc tggcaaaggg ttccactaga aatcaattta
    15361 cagcatgatc tactgatcgt ttctctactt gcgggtttag ttgcaggtgt aggaagcggg
    15421 atcgtctacc gcatgggtgg aacaacaggc ggcagtgata ttatcgctcg gattttagaa
    15481 caaaattacg gcatcactat ggggcgttcc ctattggcat ttgatatcat cgtcttactt
    15541 gcttcattaa cctatatcga cttgaaacgt atgatgtata cgttgattgt ttcgtatgtt
    15601 ttcagtcgtg tgattgattc gatcttagat ggcggatatt ctgcaaaagg tctacttgtc
    15661 gtctccaaca aaagcgaaga gattgcacca ctactgatga ccggtctgca aagaggtgtg
    15721 actttccttt ctggagaagg cgcattctct ggtaattcaa aaaaaatcat ctatatggtc
    15781 gttagctcta gtgaattaac tgaagctaag aggatcgtcc acgagattga cgaaaaagct
    15841 ttcctttcaa tcatcaatgt gcatgaagtg gaagggcaag gctttactta tttgaagcca
    15901 cagacaagat tactgaaaaa actataagaa aaaagacaaa gataggctat gaggaaagat
    15961 tccacatcca gctgaccttt gtctttttta gtactatact atttttaact aattgttatg
    16021 ttcacttacc cggttacttt tcttttgtgt ctgcaaaagg atctttcggt taacttcatc
    16081 agataatttc aaaaaagcat ccctatctcc atcttctagt gcttgatcga tttgagcata
    16141 aagcattttt agttttgcct cttcttcttt ttcttgaaaa tatcgttcaa ttaattcagt
    16201 atcttcttca ctgactgaag aatcccaaga agaaaatgga ttgtcttcta agatagatag
    16261 atattctctt gtctgccaag cattttcgaa tatacattcc acatataaag gctttttcca
    16321 attcaaacgg atttcatgaa aaatctggtc tgtgtccgta aattcttttc cctgcaaaaa
    16381 caatttcatg ggttcccctt caacagatag atcactgatc tgcagtcctc gatccgcaaa
    16441 attcgcccct tcaacaaagt ggacattgct taaaatcgct tcatgattgg caagataatt
    16501 caagatccaa aaaacttctc ttcggctaaa agatacatga ttgaccatcc acgttaaaaa
    16561 attcttcttt tcccgtacat caattagcat ttttctcacc tctctgttag gtcatctaat
    16621 aatgacagtg cctccatatc tcctggttca agtgttaaat aataagtcaa taattcttgc
    16681 gctcttttca gctgcccttc ttctcttaag aaaaaggcat actctttcaa gaaatctggt
    16741 tcatgtgata gttcatgata agcctgttca tagtgtacag ctgcaacggt aaagtcttct
    16801 aattcattat aagcatgggc taggttccat tctgcataag gattagcagt ttcttccatc
    16861 tgattgatca cttgtatcac atcttcatat ctttcatcat ccaagtaaag attacttaaa
    16921 gtaagtaatg tttcatcttg tttgtctcct acttctaaag ctttcagtaa aagttcttct
    16981 gctcgctgtc tatcatgcag acggaaagca ttttccgagg ccaggtgata aagttcgact
    17041 tggtaaggat tttctttgat tccttcttct aacactgttt gtgcttcttc aatcatttct
    17101 tcttcttgaa gagcttgtcc tagatataga tataacgatt gataatgcgg attaacttct
    17161 cgaagttctt ccagatagtt gattgcctgc tgattttctt tcaattgaag attcgtaaaa
    17221 gctagctgga acagtcgatc atctgtcctt tcttctttca gtgcttcttc taaaggtacg
    17281 atagctgctt cgaattctcc ttgcatactt aaggattgtc ctaaacgttc ctgcatcgag
    17341 attcctgaaa tttcatttat cccgcttgcc aacaatgttt cataaaccac tgctgcctct
    17401 ttgaaacgat caactgaaaa atacaattca gctagcgcaa actggatcaa tggttcatca
    17461 ggaagcaacc cagctgcttc tttcaatttt gcttcactca cttcagggat tccgataact
    17521 tggtacaaat cagctatcgc caataagctt tgcggatagt aatcactttg cttatccact
    17581 ttttccaggt attcaaaagc taagtcgatc tcattatctt cgattgcaat ttctgctaac
    17641 gggatgttca gtccgtcatt ttctgggtat tggttgatca gttgttcaaa aatctgtttt
    17701 gcttcgatca aaaagccaat agccagcaat tcttcgccta gttcagctaa tatatctgct
    17761 gggtcttctt ttaatgcttt ttctaaaaag atttgtgctt gtgacaagtc ttcatctgat
    17821 aaagcttgca acattttttc gctatttgta ttcatttcaa ttccctctta tctcactgac
    17881 gatttgttga aataccgtca ttgttctcaa taattctttt tcgtttggat gttggtatcc
    17941 gtctattata cctatttttt ctaaaacaag tatttttttg cttttttctg ccaaaaaaag
    18001 aactttttcc aaatactcca tctttgaaat ctgttccagc cagtggattg gatagccaag
    18061 caagtccagc cacacaaaaa agttttttag ttggaaatca aaaggatatg cttggagatt
    18121 ccacacgaaa tgaaacatca ttcctaaaaa ttttttcata ctagcagaaa gtagatggcc
    18181 attttcggtc agataaaaag cttgttcaaa cagtttacca taatttgaca ggttttctgc
    18241 ctctaattga taaaaataga tcatttcttc gatcatcccg gcaaacggcc gagtcgttaa
    18301 ttgcttttta tttggatagt ttttatacag attttgcaaa aaacgatgat cacaaatcat
    18361 tccgcaacag ataaaagtca aaaagtcaat ctgctttccg tccacctgcc gctcgctgat
    18421 tgtttgatca taaacgatgc gttctggcag attgatggtt tgcagcacta cacgatttgg
    18481 tagctgcaaa atcgtccgct gcggtgttaa tgctcggctt agagaacgga tcgatacagg
    18541 gatcatccat agtgatgaat caagggttgt atgtttttga aaaaaacctg ccagatccat
    18601 gatcccttca tttccaaatc cgatgataaa catggattga ttttcgggat agcgtttgac
    18661 gaaatcaagc aggttcttta attctgttaa atgattgcat tgagtgttgg cacaaatata
    18721 ccagtcattg tttgcttgat ttgcaaataa cgggttgatc ttatctgcaa acaaatcata
    18781 atagcgctga ttcgttaaaa ataagattgg ctgatcaatg gaaagttctc ttagctgact
    18841 gactagcgtt tctccgtaaa acactttcgt caacgcatct tctacttgat aatcaagttc
    18901 catacgcatc cctcctcttc ttatttttat tttaccatta gtaagcaaat tctagaaaag
    18961 ataagagcaa agctcacctc ataacttgca aataaataaa aattaaataa aatacatgtg
    19021 ttttctatgt atgacatacg gattcggaat ctctgtctct tatttattcc ttttctgcta
    19081 ggaaataaaa agaaaagcac ttgtagccct agagccacaa gcgctttttc aactgtctta
    19141 tttaacagcg tcttttaatg ctttacctgg tttgaatgca ggtactttgc tagctggaat
    19201 ttcgatttct tcaccagttt gtgggttacg acctttgcga gctgcgcgtt cgcgaacttc
    19261 aaagttacca aaaccgatta attgaacttt ttcgccgtta gctaaagcat cttgaatagt
    19321 tgaaaataca gcatctactg ctgcagttgc atctttttta gttaaatcag tagctgaagc
    19381 aactttttcg attaattctg ctttgtttgc catggataga ttcacctcct ccacaagaga
    19441 tatgatagaa atatcattta gttaaaactt tctgagtggt ccagaagttt aaaaagaaat
    19501 attgattaac ttcaatattc tgttatcacg atatcatatg aaccgcttaa tagcaaggtt
    19561 tttaccaatt ttcacatgct ttttttagtc atagaaacgt aacaaacgaa actgtctttt
    19621 tcttttgaaa aaaaaacgtc gatatggtaa aatgcctatt ttctcctacg agggataatt
    19681 cggatggacg tcccttcaaa agtaaatgct tttctgattt gattttctaa gaaacgttca
    19741 taagaaaaat gcatcaattc ctcttcattg acaaaaacga caaatgtagg tggtttgaca
    19801 gcgacttgtg tagcataaaa aatcttcagg cgttttcctt tatctgttgg tgttggattg
    19861 attgctacag catccataat gatatcattc aacacagccg aagagatacg aagattctgg
    19921 ttcatactta cttgttcgat catttcaggc agacgttcca accgttgttt agtcactgca
    19981 gaaacaaaaa cgattggagc gtaatcaaga taccggaatt catcacgaat ctcttgttcg
    20041 aaatcacgca ttgtattggt ttctttcttt acaagatccc atttattcac gacgataata
    20101 attccacgac cagcttcatg ggcgtaaccc gctactcgct tgtcttgttc ccgaatccct
    20161 tcttcagcat tcagtaccat caaaacgata tcagaacggt caatggcacg cattgcacgc
    20221 atcacgctgt atttttcagt attttcgtat acttttccgc gtttacgcat accagctgta
    20281 tctatcatta agaatttctg accactttca gaaacgaagt gggtgtcgat tgcgtctcgg
    20341 gtcgttcctt caatatccga aacaattaca cgttcttctc ctaaaatcgc attgatcaaa
    20401 gaggatttac caacatttgg gcgaccaatc aaactaaact taatcgtgtc gtcgtcctct
    20461 tcttcagtct cttcagagaa atacttcact gcttcatcta aaatatcacc aatccctagt
    20521 ccatggcttc ctgaaacagg ataaggatcg cctagcccta aggaataaaa ttcatagata
    20581 tcgtttctca tttctggatt atctacttta ttgactgcta aaatcactgg tttattactt
    20641 ctgtataaaa ttttcgcaac catctcatct gcgtctgtca cgccttcgcg tccgctgact
    20701 acacaaatga ttacatctgc ttcttcaatc gcgatttctg cttgatgctt gatctgatcc
    20761 ataaaaggtt catcgccaag atcaattccg cctgtgtcga tcacgctgaa ttctcgacct
    20821 aaccattcac cttttgcata aatacgatca cgagttactc caggagtatc ttcgacaatc
    20881 gagatacgct caccagcgat gcggttaaaa atcgtagact taccgacgtt cgggcggcca
    20941 acgattgcaa ttgttggatt tgccatatta tttcctcctc acaagtttcc aatctcactt
    21001 agtttaacga atgcattgcc aactttcaag catagattgt caattaaacg aagtattttt
    21061 attccttatt gaaatactaa tcgcttttca aaagaaaaac tgagacaaaa gcagctgctt
    21121 tcatctcagt cacagataca aaatcaatta tttttcagaa tcatcggttg ctttttcttc
    21181 tacttcttct ttcaacgcat cacctaaaat gtctcccata gtaaatccag tattttcttc
    21241 tggtaattca taagactcaa cattttttgg ttcttcttct gaagctggtt tttcttctaa
    21301 agctttgata ctcaatgcaa tacgatgttc ttctggatgg atctctaata ctttcacttt
    21361 cacttcgtca ccttcatgaa gcacttcatg tggtgtcgca atatgtttat gtgaaatttg
    21421 agagatatgg actagccctt ctactccagg gaacacttca acaaaggcac cgaagcttgt
    21481 caaacgttta actgttccgt ctaatactgt gccaactgga gcttttgtat cgatttctga
    21541 ccaaggtcca ggctgtgtgt ctttgattga caaggaaaca cgttcttgtt caggattgat
    21601 agacaacact ttgacattta catcatcatt gacagccaat acatcacttg gttttgctac
    21661 atgactatgt gaaatctctg agacatggac tagaccgtca attccgccta ggtcgacaaa
    21721 tgcgccaaaa tcagtaagac gtgcaacacg tccactgaga acatctccct catggatagt
    21781 tgaaagaatt tcttttttct tttcttctct ttcgttttcc actaccgctt tatgcgataa
    21841 gatcaaacga ttttctgatg gttcgatttc gatgatttta aagctcaatg ttttgccttt
    21901 atagtctgaa aagtctgcaa caaaatgatc ttccaccatt gatgcaggga caaaaccacg
    21961 tacaccgacg tcaacgacta aaccgccttt gacaacattt gtaacaggtg cttcgatgac
    22021 cttgccctct tggaaatctc tttcgatatc ttcccaaact tttttagcat ctaaacggcg
    22081 ttttgaaagt agatagctgc cgttttcttt atctttgccg atcgtactga taacgactaa
    22141 atctaataca tcaccgactt ttactacttc gctgatatct tctaccggca aagttgataa
    22201 ttcttttgcc ggaacgactc cttcaactcc agccccttcg attccgacaa tcacttgttt
    22261 gtcttcaatg actaaaactt cgcccttaac aacatcgcca acttttactt cttgtacgct
    22321 tttcattgcg tcttccattg actggttgtt ctcttgattt tgatcaaatt ctgtcataac
    22381 acttgtcctc ctaaccaaca ttctgccgta agtacggtac tgtttttagt ttaattgatt
    22441 attcaaaaaa aataaagcga tttcgttcgt tttccttgaa aaaacaattg tttttcattt
    22501 tttttcttaa tttaaaaaag aagataacct tttttcaaaa caacagcttt tattgctgca
    22561 acgacttctg gaatcgattt gccagtcgta tcgatacgaa cagcatcctc tgcttgcttc
    22621 agcggagaga cgtcccttgt tgaatcataa tggtctcttt cctgtatctc tttcgtcagt
    22681 gtttcaagat cagtcggaat tcctttttct tggttctctt tgaaacgtct ttctgcacgc
    22741 tcacttacgc ttgctactaa aaagattttc acttctgcat tcggtaatac agctgtcccg
    22801 atgtctcttc cgtccatgac aacgccaccg cgttccccta tttttcgttg gacagcaact
    22861 aattcttctc tgacttttcc atgtgcagag acttcagaaa cagcttttgt gacatctggt
    22921 tgacggattt ctaaagtcac atcttttgat gctatgaata catgctgtcc atcttcttgt
    22981 tgcgaaaaag agataggata ctttttgatc agcgaaacta gcccttcttc atctgaaaaa
    23041 gatacattgt tcgtaatagc taaataagtt actgcgcgat acatggcacc ggtatctgta
    23101 taaatataat tcaattcttt tgctaatatc ttggcaacgg tacttttccc agatgaagca
    23161 ggcccgtcga ttgcaatact gatttgtgtc atgatataac tcctttttct cagaaaaaaa
    23221 gccgcaaagc gcggctatta ttatttaatt cttaattctt gaccagggta aagcataaag
    23281 ttgtttggat ctaagccatt caattcaaac aattgatcag tggtgatccc tgcacgctca
    23341 gccacttgtt ttggaccttc gcctgcttga acagtcgttg ttgaaccggc tgcagctgat
    23401 gaagaaggtg ttgtttctgc tgcattgctg cttgaatccc ctgcttgata agttgcctca
    23461 cttgaggaag tcggtgttgt ctctgctgca atactgcttt ctgacgttac acctgtatct
    23521 tgagacacag tagattcttc cgcgattgta ctagattcta ctgttgaagt ctcagttgac
    23581 tcctcttttg ttgtacttgt agaactttct actactgatg tcgaagtttc agaagaagtt
    23641 gctgctgttg cattgttgct tgatccattt ctgatccaga aataagcacc tgctggaata
    23701 gcgatacata agaccagtaa aatcaaaaat agcgaaagaa ataatgtatt tcctttcttt
    23761 tgttgtctct gagaacttct tgatgaaact tcatcatctg tatcgtagat tggttgttcc
    23821 catggttctt gtgtttcgtt attttctgta gattgatgtc tatcttttct gctcactgtt
    23881 ttacctccta aactctatcg tgtgtattat accataggaa aaagtgtctt gtcctaaaaa
    23941 atcaatgttc catgtttttt ttaaataaat ttagtaaaat cgtttcccaa tgaagttgtt
    24001 cagtcttaga aaaaagcttc ctctttggca gaagttctgc ttttgctcca tcaatatcac
    24061 aacaattctg cggcttttcg gagagttttt cgccaaaata agctaagatg aattttctgc
    24121 ggcagttttc ttcattaata tagcgaagca tctgctgcag gcggaattct ttttcttttt
    24181 cctgacgttt gagccgttcc acccaatttt ctggtttttc agactgctgg atcagctcca
    24241 tccatttttt ttgcagctca tcaaagggag cttgctctgt ggcatattcc aaataaagct
    24301 caaaactttg tcgctgttct ctagaaagtt gattaaagaa ataatggata cgttcatccc
    24361 cactttgata aaaaagaatt gctgcacttt cttcctgatc tctgcctgct cgaccgattt
    24421 cttgtacata gttttctaga ctgtctggca aatcataatg gatcacataa cggatatcag
    24481 atttatcgat ccccatacca aatgcattcg tagcaatgag aaactgcagc tgatttttta
    24541 caaactgctg ttgaagttgt cttctttgag ctgcatcaag accaccgtga tagtatccaa
    24601 ctgtaaaacg ttccctgaat aaatgataca atcgttcgac ttcttttttt gttgcacaat
    24661 aaatgattgc cgctccttgt gctctttcca tgaagtgttc aagttcttgt tctttttgct
    24721 gcgttttccg aacaaaaagc gagatatttt gccgattgac tgattgtctg atctcttttg
    24781 gtggtcgatc aaatagtaca tgacgtatat ctcttgctac taaatctgtt gctgtcgccg
    24841 ttagtgccag tgtgaccggg tttcctaaaa gctttcggat ttttcctaac tgttgatatt
    24901 ctggacggaa atcaactccc cattgagaca cgcaatgagc ctcatctact acatataacg
    24961 caatattttg ttttttcaga tgctctaaaa gagaaggatt agtcaacatt tcgggactca
    25021 aaaacaaaaa tttatattgc gatagatgac ggaggacgta tcttctttca gattgcgaaa
    25081 gtaaactatt gaaagcagct actcgtttct cccctcgttt ttgtaattgc gtcacttgat
    25141 cttccattag agaaagcagc ggtgacacga tgatgaccag accttccatt aaaaaccccg
    25201 tcaattgata gcaaaggctt tttcccgttc ctgtaggcaa aatagcgaga gtatcttctc
    25261 catcaagcaa cgcctgaatg atttcttctt ggccgggacg aaatgaatca aatccaaaat
    25321 atttttttaa ttcatttatt aacattctgt atcgcttcct ttctcaatag atagatttga
    25381 tacaaacgaa attctccata atctaattgt ccatctacat tccattcgct aaagcgccac
    25441 tctcgcacgg aatccttatt tggttccaaa cgttcgattg tttctgcaga gagaatccgc
    25501 tcgtatggaa aatcatcaaa aaacaaggcc cactcaataa gatgatctgt tactgttcct
    25561 ctttttaaat gacggattgc cataatctgg tcaattgtct gaccattcat aaacatctgc
    25621 ttggtgatca tcatgctttg attgaaattt tgctgtaata atgaatcgat caaagcgtgc
    25681 caaagcgaat ctggccgttt ttcgatttgt gctaacaaaa ggtggataca tctgctttgt
    25741 tgcagataaa ccgctgactc atcattgttt tttgccagct gataaggaag cagccctgtt
    25801 cgctcatttc cagataattg gttagctaaa aaatctgctg cttcttctgg tatctccgaa
    25861 aacagctgca ccaaactctc atacgcagta tcaatcaaaa tttcacgtgg caattggctt
    25921 tcactaagcc atttttttag ttggaaagta taaaaaggac ttgtctctgc tggaagatag
    25981 tcttgaatac ccgttgccag attagaaatt acttgaacag caaatttaat gagccgccaa
    26041 ctagtttccc ctgttctgcc atagcggtca aaacgcaaac cagtatgttc tatttgatgt
    26101 tcggacaaca tatcagcccc tgcaggcgtt agctttgctt cattttcatt tatttcgatc
    26161 caaccttgct gcgcaatttt ttgcaaaatt tgataaaact tatcctgctt caattctgga
    26221 aaactgttat ggataaacaa aagttcgtgg gtaaatccat aaataagtac tgaagtcgtt
    26281 cgttttccca caaggagttg gtaaagagaa ctaatccgca gcttgtgtcc tgatgaaaat
    26341 agcgataaaa taaaaacaat catattattc tccttaagtt aggatggtta gaaatgtcac
    26401 tactatgtaa acttgtacct gaacgctgta ttgcatgcgg tctttgtcaa atcgaagcgc
    26461 cagatatttt cgattatgat gaagaaggaa tcgttttatt tgcccaagaa ccagaggctc
    26521 atcaacagtt cgtgatgccg gaagaagaaa catatgtaaa aaaagcgtat caaaaatgtc
    26581 cagttcgagc gattttatta gaaaataaaa tataaatata aacgaaactt taaaaacgta
    26641 cactaagttc tctaaacttg aaaataagcc gggatctgtt tctcttgttc cgtgaaatcc
    26701 cgacttattt tgaaagattc atttgctatc tatagttaat tgactagttt tttcacggac
    26761 cctataggac ccatttatat tatttcaact ttttcagcca gttttccaat gtattgacga
    26821 tcacagtttg ctggtctgcg ttagaaattt ctgcctctcc atctcctttt tgctcaccat
    26881 agctgccaaa acctccatga tttccgccat tgattgatac atactctgtt ctttccggta
    26941 aatactgctt agcttcttga taagcttcct gattcaatac tttatctttt gtcgccgtga
    27001 tcgataaaac aggaacagct gattctgtca atgttccttt tttgtcggga taacttgcca
    27061 tgaagaatac cccttttaaa tgtttgtctg aatgattctt attgacataa cgacttgcca
    27121 ttacgccacc taatgaatgg ccaccgatca cataatcgga atttggaaaa tcttctttga
    27181 ccttatccgc tttgtttccg cccatcactg ctagatcaag tggcattttg acaatagcga
    27241 ctgaaaagcc gttttttgct aaatcttgcg cccaaatact ataactttct ggctctacga
    27301 gagcaccagg ataaaaaata agtaatggag aatttccatg attctttttc tctccttcaa
    27361 aaaataagta atcttctttg ttttttcctt cttttaccaa cacttgcgct tctgacgatg
    27421 gttcgtacgt attttgctgt atatagtaat aaccggctcc accgagtaat cctaaaatga
    27481 tgactaagcc aattagtatt cgtctaaata ttttcacttt ctcccacctt ttctatctga
    27541 gtgacccctt tttcttaatc aagtatgatt ataccttaaa aaaaataaga gagaaatgca
    27601 aactttccag catcaaataa aaaaagacgg aatatccatt tgaatatccg ccctttttgt
    27661 atgtttattt ttatttagca cataaacgat acacagcttc tgcataaatt tccattgctt
    27721 tatacatact acttaattcc catcgttcat tcgcctggtg cataaagtca ggagtatcag
    27781 ggaacatcgc accgaatgcc acacactggt tcatcgtacg agcaaaagta gcgccgcctg
    27841 atacaaacgg ttcagtcatg tctccagtaa tatcgcgata tgtccccaat agatttttca
    27901 ctaactcact gtctagtggc acgtataatg aatcaaggaa gtcaaattct tcataagtca
    27961 acccatattt ttctgctgtt ttagttaatt tagctactaa atcatctttc ttgaatgtaa
    28021 cagggattct catatctaca ccgatttttg tttgttctgg tgtgatttcc aaacttgcaa
    28081 agttcatcgt tagctcgccg gattgttcat cttctgtttt gcccacgaca gcttcaccag
    28141 ttgcattttc ttgaactaat tttcctaaga aattgattgg gccaaaatcg aatacttctg
    28201 aaagagcaat tgccagacga gaaatagcat tcactccttg tgctgcatct ttcgcgtgga
    28261 tacttttacc aagaacgacg atgccttcac cttgttcttc gaaatcgaat tcgtgttttt
    28321 tcaacgcttc ttttacttca gaaagctttt ctccagagta aggagctgca tcaggaacaa
    28381 cattcaacgc tcctccagct tttacagaaa actcgttcgt tcctggtcct gtcaagtaag
    28441 cttgcaataa gcctttttct gcataaatta aaggaaattc agcatctggc gcaaatcctt
    28501 gcgtaattcc ttcttctttt tcgttatatt tttctaaaca acgccataaa ttttcttcat
    28561 ctgtaccaaa gataaaacga atacgtgtct tgaattccac gccagcatca atcaaagctt
    28621 tgacggcata cattgccgca atagaaggac ctttgtcatc ttgggatccg cgaccaacta
    28681 accagccgtc ttttatagtt ggatcgaatg gttttgtttc ccaattattt tcgtcccctg
    28741 ctggaacaac gtccatatga cacaagatac cgaataattc atctccagag ccaatctctg
    28801 aataaccgta atagccttct ggatctttaa atgttctaaa tcctagcttt tcactgattt
    28861 ccaatacttt atccaaagct tcaatcactt ttttaccgaa gggatgtcct tgtcctgaat
    28921 ctgcttcatc tagtacggaa ggaattcgga tcaattcgct caatgattct aatgcttgtt
    28981 catgatgttg ttctgtcaca aattttttca tgatattatc ctcctaatat gttaaaaagg
    29041 gtcatgtcaa attcctccga cacaacctct tcttctcaaa taatgacgtt ttaagcctgc
    29101 tccatcagca agcagaatgt tcttaacaaa tgatgaaaga aaaaacactc actgaatgga
    29161 gctattgact tgtccacgtg cttatcgata gccgtttatc ggtttcttca ttcttatgat
    29221 agaccttgta cctgtatttg tctaggttta gaacattgct gctacaccta ggatcacaca
    29281 gatggctaca aataatatcg caattaattt accggtaaat ttccaccaca ctgaaacatc
    29341 gaaacgagca attgctacag cacccattac gatagcagat gttggtgtaa ttaagtttac
    29401 taaaccagat gcagattgat aagcagtgat tactaaatcc ttaccgacgc cggcaaattc
    29461 acccataggt cccatgattc ccattgttgc agcagctaag ccggaagttg aaggaatcaa
    29521 gaatgacata gggatataga aaataaatgt aataatgatg aatacacttg aagataatga
    29581 acttaatcct tgttcgcccc aatgtaagat ggtgtctgtg attaatccat tgttcataac
    29641 cacttggata ccacgagcaa cagctactac gattgctaca ccgatcaaat cagaagcacc
    29701 agctaaaaat tcagagacaa attcagactc tttcatgcca taagtgattg ctactacgat
    29761 ggacattact aagaataaca tagtaatttc tgggaagtac cagtcaccta atggaagcat
    29821 gcttttacct agaacagtac ctagtaccgg aaggtttgtt aaccagtttg tcaatgattc
    29881 aaaaatcgtg aaattcgcat tcaaggttgt ccaaggaatc aaactgatga tcatgatacc
    29941 aaaagtaata aagaacaata cattaacatg tttttgtttt ttcgtgatta cttcttgacg
    30001 accgattgct tcaatatcga aatgcttcat atcttcttta cgttggttgt atactaatga
    30061 ttttgttgga tctttttcga tctttgatgc ataacgatac acatatacaa tagaaatagc
    30121 taacaaaata acgaacatca agaatcgaag accaatacct tcacccatcg aaatcccaac
    30181 agcttgtgaa gctacgcctg ttgcaaaagg atttaccgtt gaagctagac agcctacttg
    30241 agaccctact aatacgattg ctactgctac tactgtatca aagcctacag ccatcataac
    30301 tgggatcagt aaagcataga atggaatcgt ttcttctgcc attccgtaag tagagccgcc
    30361 taatgcaaat aacagcatca atactggaat aagcattttt tcttttcctt tgaatttctt
    30421 cacaactgaa gcaatcccgg catctagtgc ccctgttttg ttgataatac ctaaaaatcc
    30481 accaacaacc aaaatgaaga aagagattgg gattgcagca ggtgtttctt tagttagctc
    30541 ccccgctggt acacctaaca tcccattgat tggcgccatg aaaatatccc acagcccttg
    30601 aggattttgt tgtactcgtt catatgatcc agcgacgatg ttgcctgcat cgtctacact
    30661 atagtgccca gctggtataa accaagtaag tacagcgatt actgcaataa taataaataa
    30721 gaccgtatac gctgaaggca tttgaaattt tttctttttt gtttgttcca tcttcttctt
    30781 cctttctttt ccgttagaga caacaatttt ggctctaatg ttattttatc aaaaagagta
    30841 tcagaacaaa aataataaca cgcattttgt aaaacttttg ttcaaaaagt tcgtttttcc
    30901 ctattccctc ctcttttttc aggtttttaa agctttcttc tttttcattg tagcgtttcc
    30961 ttttttttat aaacaaacat tttcgtcttt taaaaggaga agaatttcac atttgcaaag
    31021 aattgattga tttttatgca taaatcaaaa aaatactcaa aacaaacaaa taaaacgttt
    31081 acattattgc atgtcttgta tttttttcca aaaaaaaaga ccaagaaatt tcttgatctt
    31141 tttgataatt atttgactgc tgtatgacgt tgttcgaact gatgttgttt tcgacttaac
    31201 catggaagaa gttgcgcatg cagcactaaa aagacagcgc tcacgatgaa tcctttgatc
    31261 aagttgaaag gaacgatccc aatcagtaca tagtttgcta aagacatgcc tagcatctgt
    31321 gttgcgttca gtcctaaaaa cattaagtaa agaggcgtaa taacgaaata atttgcgata
    31381 ctcataaaaa tagttagagc gatggttcct gtaatgacac ctaaaaattt gtttcttcct
    31441 ttatgctgtt tctttacact aaagaaataa taaatcggga atgtaaagat cgttgttgat
    31501 aagaaactag cagtgtctcc taccaaatta tccggagaaa aacctgtagt cagcagatgt
    31561 aatactgaac gcaagaacgc tgttgcaact ccggccgctg gaccgaataa gaacatgctg
    31621 atcaataccg ggatatcact aaaatcgatc ttcaaaaaac taaaagccgg catgatcgga
    31681 aaagcaaaat actgtaaaac taacgcgatc gcagcaaaca tcgctactgc aaccattttc
    31741 tgtacacggg tgttcttcat ttgaaatcct cctgttagga ctcctcttca gcgaactttt
    31801 tgacgtttct ctccaaatga aaaaactcta ttttccaggg aaaatagagt tagagttatt
    31861 tgatcaagcg tcgtcaaata agctctatct tctttatcca gactatactg tcggtatcgg
    31921 aatttcaccg attcagctat tttttgcaaa ataggtcgtg gactataacc accggtcggg
    31981 aatttcaccc tgcccctgaa gacgaacctt atataatttt tgtttacata ttcattatac
    32041 atatctattc aaaaaacgca acatctaaca cttataaaaa gtaagtgttc attttgagtg
    32101 gttcagcaaa ctgctgactt cttttttgtt cagttcacgg taatctccag gacgtaggcc
    32161 ttgtaaagtc agatctccgt atttttcacg ttttagtttt tgcacaggaa gaccaactgc
    32221 ttgaagcata tttttcactt gatgattacg tccttcgtgg atcgtcaatt ccacgatact
    32281 gtggtttgtc ttaggatcca ctgataaaat ttggaattta gctggagatg tttttcgtcc
    32341 ttcgatcttt attccttttg tcaaaggtgc aagcatcgat tttgtagcga tcccttttac
    32401 ctttgcaacg taaactttat ccacttcatg ttttggatgt gtcaggcgct gagcaaaatc
    32461 tccatcattt gtcagtagca agatccccga agtatcgtaa tccagtcgac ctacaggata
    32521 gatacgttct tttaccatcg gcaaaagatc cgtaacaact tttcttcctt tgtcatctgc
    32581 aacagcagaa ataactcctt taggtttgta caataaataa taaccgtatt cttcttgata
    32641 aattgggact tcatccactt ccacagtgtc atgtttccca acttttatcc ctaattccct
    32701 tacaacttgt ccgtttactt ttacacgtcc tgcaaggatg aattcttctg cttttcgacg
    32761 agaagtgatg ccagcgtggg caattacttt ctgcaatctt tccattacaa ttattctcct
    32821 ttattcattc catcaaagaa tagatctggt gacacgtctt cttcaaatga aatttccatt
    32881 tcttgtgtat caggcagttc ttctaatgat ttcaaaccaa aataatctaa gaagtagcca
    32941 gttgttccat ataatatcgg ccgacctggc ccttctactc tacctttttc ttcaatcagt
    33001 ttatgggcag ctagacgctg taccgctcct gaaacctgaa ctcctcgaat ctgctcgatt
    33061 tcagctcttg tgattggctg tttataagcg atgattgcta aggtttcgac agcggcttga
    33121 gataatgtgt ttgatgtccc ttgcgcatat cgcttaagta agggagccag ctctttttta
    33181 gtcgttaata cataatggct ttccgtttca aaaatatgca aagctgagtg cgagttttga
    33241 gtgtaagatt cttttaattc tttcactaaa cttgtgactt ctgcttcgct gagatttaac
    33301 agtccgctta attcttcatt actgatccct tcctcgccaa caataaaaag aagggcttca
    33361 agttcactta atttcgtcat gttcggtatc tcctactgct ggataaagca taattgattc
    33421 atagttttct ttttgttgcg caatgatctg cccttttttc atcaattcta gcaaagccat
    33481 aaaagtagtg acaacttcac ttttagaagg tgactcaaaa aaagaatcga aagtacagcc
    33541 atgcgcattt ctttttatac gctcttcgat aaataccatt cgttcttcga tcgttgtgtc
    33601 atcgggcgtg atcgtttttt ccactttttg agaaaatttc ttacgttcta agattttctg
    33661 catggcacgg atcaaatcga tttttttgac ttgtcctcgc ttcaacggct tttcagcatc
    33721 cgctaaccca tcgatgttca taggttcttt tgtgtaataa agacttcgtt cctctgcttt
    33781 ttctgtcagt ctttcagctg catatttata tttacggtat tctaaaagct gagtgaccaa
    33841 ttcttctcga ggatcttctt cccataattc ttcatcatct gtgacgaatt cttggacagg
    33901 aagcaatgtc ttgcttttga ttgccatcaa tgtagcagcc atcactaagt attctcctgc
    33961 aacagctagc tctagtgttt tcattgtatg gatataattc atatattgct ccgtgatcgt
    34021 agcgatcggt atatcatata tatcgatttc catttgctga atcagatgaa gcagcagatc
    34081 gagaggacct tcgaatacat ctaatttaat attgatctcc gtcaactcat tcactctttc
    34141 ttctttttct ttgctagcca ttttccaatg taaggctctg tgatttcagt tgcacggatg
    34201 gagacatccg ggtacttttc ctgtaattca tctaacattt gaaagcccat attctcaccg
    34261 cgataagacg gattcaaaga aatgtcatgg atgatcagct gatcgttcgt tgcccagtaa
    34321 acaccaataa tcccttgaat gttggttgaa ccttctggcg taaagaaaaa aagttcataa
    34381 tcgtcttcag attcgtacgt atcaatctcc ttcaacaaag aagttttacc tgtcagtttc
    34441 ttatggaaac tcaatagtcc catagcaatt ttacggtttt ctttccggta atgtgttaac
    34501 atcttctcac cttcctatga ctaagccctt ggaaaatgct gcttataaac atccgtcatt
    34561 cttttcttcg tgatatgtgt ataaatctga gtcgtagaga tatccgcgtg acctaacaat
    34621 tcctgtactg tccgcaaatc agctccattt tctagcagat gtgtggcaaa gctatgccgc
    34681 agcgtatgtg gtgttacttc tttgtaaatc ccagcctctc gtactagctg cttcagattt
    34741 ttccagattc cttgccgaga aagacctttc ccatgattat tgacaaatac atgcatttca
    34801 gatgcgtcct ttacaagtaa tggacgtgct tcgtctaagt agcgttccag ccattggatc
    34861 gcataatcac ctaaaggaat gatccgctct ttatctcctt ttccaactgt ctgtaccagt
    34921 ccaagagaaa gatgaagatc tcccaatttc aatccaatca attcactgac gcgcatccct
    34981 gtagcataca tgacttccaa gattgcacga tctcttatcc ctaacgtttt tgtcgtatca
    35041 ggtgcttcaa tcagcttttc tacttctgtc agagtcaatg tacttggtaa tttctgtgct
    35101 ttcttcggcg tatcgatatg ttgcatcgga tcatgatcag tgatacgctc ttgccgtaaa
    35161 aactgatgga atcttctgag acttgagatc atccgagtaa cagttgctgt cgcttttttt
    35221 tcttcatgca acttctccag aaaacggatg actaaaaagc gatcgacatc ctgccatgaa
    35281 gcaattttct gctcctgtag aaaatgcaag tactgttcca aatcacgttc atagctttgt
    35341 cgtgtattgg cggacaatcc ccgttcaata ttcaagtagt ggagataatc gttgatttgc
    35401 tctttcataa taatccccct catgcctctc tatcatatca gataccgctt cattctgata
    35461 gtctttttcc ataatctgag caaagaaaaa gccgtctaga cactcagacg gactggtttc
    35521 ttttttcttt ttcatagcat tcctgacaga ttccatggaa cgttagccga tgatctttta
    35581 ctaaaaaatg ataacgttct tctactactt gctccacttc aagtaaaaga tcctcttcta
    35641 cttcctcgat cgtgccgcag ttcaagcata gtaaatgatg atggaaatgt ttggcgcctt
    35701 cttttctcaa atcataacgg gctaatccat cattaaaact tactttatcg acaattttca
    35761 attctgtcaa gatttcaagg gttcgataaa cagtagcaag tccaatttcc ggactctttt
    35821 ttttcactaa aaagaagatt tcttctgcag ataaatgctc tttctcattt tccaaaagca
    35881 caagcagagt agcttctctt tgcggtgtca gcttaaaccc cgcttcatgt agctgctgtt
    35941 ttgttttttt catcgccgaa atagcattca tgaccattta ctcaacccca acaatttata
    36001 ataattacaa ataaaaaaag atataacact atgttaatta aaattattat aagctagtta
    36061 agaaaaacat gcaagggatt ctcaattaga ttttttgact agttttgtca caccgttttc
    36121 ttgtgtaatc aatccttgtt tcaaaagatt acctaatgcg cgcttaaatg ctcctttgct
    36181 gataccaaaa gctttcatga tttcttctgg atccgattta tctgtaaagt tgatttgctg
    36241 atctgcagaa cgttctaaaa tggttaaaat catttgtgca tcatctgata tagcttcata
    36301 tgctcttggc ttcaatgaaa gattcagtac accgtctggt cggacaccaa tcactcgacc
    36361 ttttatttgc tcgcctagac gaggttcatt atatcgttca gaaggatgga taaacccaag
    36421 atagaaatct tccgttaaaa cgtacgtacc tgttaatttc aagcggtatg ctgttcctat
    36481 cacatctttg tttttcattt cttctgttcc atatttgctt aaagatttga atattttttc
    36541 atctgctaaa ctgccccaaa tacggtcttt tgcatcaact ctaagggaaa tcatcaagcg
    36601 atcccctttt ttaggccata gctctgtcat tgtcggcaat tcatcaagag atacgacaaa
    36661 gtctttatct ggaagaccga tatcgacaaa cgcacctaaa tcttttcgtg tagcagtaac
    36721 gattccaaaa gcgtaatgac cgatacggct tttaggaatt tgtgtagtga tccgattttc
    36781 atgtttttga ttttggtagc cgaatccttc cactgcttca ccgattttgt gttcaccttc
    36841 tgatttgctt aagccaaagg tttgtccgtt tttttggaca aagtagtttt tttcattttc
    36901 atcaataata atacctgtaa atatagttgc taataaatcg ttcatttttt tctccctcta
    36961 tagtgaaagg ttttcttaat acatttcttt gctatcataa cataatgtta tctacttgaa
    37021 tagctgagcc ttggtttgga aaggtgaaaa aaggagtatg acaacagttg tgtcatactc
    37081 ccctttttcg aataaacggt gttaaacggc aggctcacag cctctttcat ttgcctaaaa
    37141 ttaattgctc ccatttcctc cgaaccatcc agttttacag ttgatggtta cgatgtaaaa
    37201 tggcaaagca ctttctccaa tgcctttcat caatgcagat tttgttgaag tggcatatag
    37261 attgtaatag ccttccccat tttcgattct ggctttttct aatctgtatc ctccttcaac
    37321 gatatatcca cgttggatac atgtagcaat cactttgctt tggacacctg gtgcccacgt
    37381 ccatgctgga ttagatgcat cggcaatatc acttgctctg gcagatttga ttggctgatt
    37441 cgctgagttt gaagaggaag gggtcgagga tgccgcttct tgctgtgctg cttgtgcgac
    37501 cgcagcttgt tgagcggctt gagctgcagc tgctgcttga gcggcttgtt ttgcttgttc
    37561 ttcagctgct tttttcgctt tttctgcttt tttcgcttct tctgcttttt tcttttcctc
    37621 ttcttctttt ttctctttat cagtgagcat cttatctact tgttgcaatt gttcattcaa
    37681 ctgagcagat agatctgtat ttttcacttt ttctactgct tcttttgccg tcttgtattg
    37741 gtcgcgtgtt gctgaatcca ctacttttcc gtctttaaag actatagctg ttttttcttt
    37801 agctgtttgc aattcagcat attgattttt agcttctgtt tgtgcttgtt gaatcaattt
    37861 tccaaaatct gtgttatccg tttcgattgc ttggatctct ttatctgctt tcaacttgat
    37921 gtcatctgct agatgatcat cgacgatggc aggtgctatg aaccactcat tcactttttg
    37981 gatatctcgg atcttagatt ggatatcttg gtaagttgtt tctaactctg aatatccttt
    38041 ttcattctta agactggata aatcattttt tagttttgat aaatcttgat gaatcatatc
    38101 tgcacgaata aattgatggt gatcatctgt ataaaaggca gcaagtttct catgaagttc
    38161 ttccatttgt tgctgtcttt ttgcttctgc tgctacttcg gcttctactt tttgatgatg
    38221 gtcataataa gcccagcctc ccccacctag tagaagaact gctgctaaag cgagatacgg
    38281 cacttttttt gattttttct tttgtgtctt atctaaatct tttttttctg ggtttgattc
    38341 ttgaggcgtt ttttcagtat ttggcacgat tgttattggt tctgtttctg cttcaatcag
    38401 ctcaggctgg ttctcttctt tttctatttt agcttcaaga gcagtgctat cttcacttgc
    38461 agattgagtt tcagcatcgg cttcattatt tattccatcc gactctgttg ccttcttgtc
    38521 tgctttttcg agcatttctt ttttatctgc ttccggcaac ccattcgatt tctcgtcttc
    38581 tgattgtttt tcagacaatg tttcagtttt ttccgggata tccgttttta gatcattcgt
    38641 ttttagatca ttcgttttta atgattcttt acctgcagcg tttactccac taatgtcttt
    38701 ttcagtgtct ttttcagctt catgttctgg ctctactttg ttttcctgtg caattttttc
    38761 actgatcatt ttgagcagct ctttcgcgtg ctcttctttt gtatcttcac gatgtgcttt
    38821 gatataagcg gatagtatcg aattttcttc ctcattatcg acgatttctt tcagttcagc
    38881 tactcttctt ttttgttttg attcaagcgt ttcttcttga ttctttcctg attcttccga
    38941 agtctcatga acagttgctt tcttctgttc atttttctct atattagtta cttgatcgtg
    39001 agcaggtggt tcttcgtctt ctggttctgc tttttcgaat aattccatta cagattctag
    39061 aggtaaatct ttcaattccg accattcgat tggatcgttt aattctgtat caggaaagac
    39121 tgcatcttca gttgatttat cctgcatagc tgcatctgta tttgtttctt caattgattc
    39181 ttttatttgc tgatcttctg cagttatttg atgaccgcag tctggacaga tagtattctg
    39241 ctccattttt ttcgatccgc aatttggaca ttttttcatc acttagcgat cggctccttt
    39301 actaggttta cgctaccatt taatctatca tattctatac gtcacgccaa tagcttattt
    39361 ttaggattta cttaaaaata atgaatgaat ttccttccta tagaaaaaaa agcttgagac
    39421 tgcgtagtct caagcttttt ttcttttaaa ataaaccaaa cagttttact gatttctctt
    39481 ctggtcaata gttcatgctt attctaagaa atcttttaat tgttttgaac gagaaggatg
    39541 gcgcaatttt cttaatgctt tagcctcgat ctgacgaata cgttcccgag taacaccaaa
    39601 tactttccct acttcttcca atgttctcgt ccggccatca tctaaaccaa aacgtaagcg
    39661 aaggacattt tcctcccggt cagtcaatgt atctagtaca tcttccaatt gttcttttag
    39721 taactcataa gctgcgtgtt ctgctggact tgttgcttcc tgatcttcta tgaaatcacc
    39781 taagtgagag tcatcttctt caccgattgg cgtttcaagt gaaacaggtt cttgcgcgat
    39841 tttcaagatt tctcggactt tttctgttgg aagatccatt tccgcaccga tttcttctgg
    39901 cgtaggttct cttccaaggt cttgcagcaa ttgacgttgg atacgtatca atttattaat
    39961 tgtttcaacc atatgaactg gaatacggat cgtacgtgct tggtcagcga ttgctcgagt
    40021 gatggcttga cgaatccacc atgtagcata ggttgaaaac ttaaatcctt tgcggtagtc
    40081 aaatttttca actgccttca tcagtcccat gtttccttct tggatcaagt caaggaactg
    40141 catgcctcgt cctacataac gtttagcgat acttactact aaacgaaggt ttgcttctgc
    40201 cagacgctgt ttcgcttctt ggtcgccttc ttcgattttc aatgctaacg ctacttcttc
    40261 ttccgcagtt aaaagggaga cacggccaat ttctttcaga tacatacgaa ccgggtcatt
    40321 gatttttaca ccggttggcg cagatagatc ttctgttttt gcttgttcag cttttttctc
    40381 agcactcttc aagctgtgaa ttgatggatc accattttca tccaccacac tgatacctgc
    40441 gtcttcaatc ttttggatca atttgtccat ttcatctgca ttcaaagtga atggtgtagc
    40501 aagctgattg gataaatcat catatacaac ttgtcgtttg ggtttgtttt ctttgatgaa
    40561 agctgctact gctgcttcat acgttttttt atctgttcca tttgccataa aagaaggccc
    40621 cccttgagta gctatttggc ttgttttaac tgtttcgtta aattgatgat ttcaatcgtc
    40681 aattcaagct caagctgttt gtttccagtt cgtctggctt cttgctgcat ttgttttttt
    40741 aatgttattt catcagctaa gccagatttg ctgatcacat ctagcaagtc ttggatttct
    40801 cgtggcgaac tttcttctgc caccggtaaa tattcgattt ccaccaccaa ccgccttaaa
    40861 ttttcatctt gcaaaaagtc taaaaactct gcaaggttga attcataatg ttgtgagaca
    40921 tatgcatcga ataaaaaata aacttctgca tatgcatcat gaataaactg aaattctcgt
    40981 tcttttaaaa tattacggac agaaacttct ttaaatgcac gatataatag aatctgctct
    41041 gccttttcta cttgcgtcaa aggtctcttt ttccgtgcag tttcttgtct cgtaacctga
    41101 gtgtgttgac tttcctgagg ttcttgacga ttttgctgat ttgtccttcg aagatcgcgc
    41161 agttgttttt gtatcgtctc tctgccgatc tgaaactctg ttgacagttg agatagatac
    41221 atatcttgtt cgattggtga aacaactcgg ctaagttcaa ctagtaattc ttcgaggtat
    41281 tcgatcttgt ctttttcatt atctaaattt ttcccttgtt ttaaataacg tgatttaaaa
    41341 gtaaagactg tttcgcgccc atgagccact aattcttgga aagatgcttc tccatactta
    41401 cggagatatt catcaggatc aagcttttct ggaacgacta cgacagaaag tgctaagcga
    41461 ctgttttgcc gaagcaattc aatccctcga ttggttgctt caaaacctgc gttgtctccg
    41521 tcatagcaaa agaccaattc tttcgtcagc ttttccattt gttggatctg ttgagctgtt
    41581 agacttgtcc ccatagaagc taatccagtt ttgataccag cctgccatgc agcaatcaca
    41641 tccataaacc cttcgaacaa caaaatttct ccgtttttcc ggatatcgct tcttgcttta
    41701 tcaagattaa ataaaacttg tcttttattg aacagttctg tttctggact attcaagtat
    41761 ttgggctgat ctttttcctg ccctttttca ggtgcaagcc agcgtcctga aaaaccgatc
    41821 gtctggcctt gagaattacg aagtggaaac atcactcttt gataaaaacg atcagacata
    41881 cggccatcat catgcgtgac aaacaatcca gagcgttcta acaattcatt tgaaattgat
    41941 tcattcttga atacttgctg aagaaaagaa cgctcattag gtgcaaaacc tatgttgaat
    42001 tcttcaatta attctaaaga caacccacga ctttgcaaat attctaaagc tggctgtcca
    42061 gcttttgtat gcaatagcat gtgatgatag atttccgctg ctttttcatg agcagcaatc
    42121 agtttccccg tagcagattc aggattttgg acagctatag tacgctgacg ccattgatct
    42181 tctaacggta tctgttcgaa gtctgccact tttaccactg cttctggaaa acttagacct
    42241 tctagttctt gaagaaaagt aaacacgttt ccgcccttac cacaaccaaa gcaatgaaaa
    42301 atctgcttgt cttctgcaac agaaaaagac ggtgtacgtt cttcatgaaa aggacacagc
    42361 cccaagtaat ttttaccaga ctttttcaac tggacatatt gtccaatcac ctcaacgata
    42421 ttcgtttgac tgcgtactgt ttcgataacc tcttgaggaa tccgttgagc catttttcca
    42481 ccccctgctc tattgatatc ttttgggttt aacagaagat atttcaggag aataaccggt
    42541 aaaaaatcgc actaactgaa atcagtgcga ttttaaagga cacaattata catgtttgat
    42601 tgtatcatat ttcattgctt tttcaagtat aacacatttc tatctcatta agcatcaatt
    42661 tgctactctt ttcagtaact gattttgaat atcagccttc cagtacaata ctcgaagaac
    42721 aatatttacg agcatgaata caaagaagta tcctacgctc tctcccaacc ctaagtttac
    42781 ttccaaaatt ccatggaaca gcattgcagc tacatatatc cctacgatcg tcgttactgc
    42841 taggaagatg cgcaatgggt tgaagggata acaagctttt acaactgcca tgcaactgat
    42901 cccaatcagc aagtaataca tcaaagtagt agtttcagca tttccccatg cgaatgtttt
    42961 tccaagtaga tacaccgcaa tgatattcac tactacaagc aaggcatttg gtaaagcatt
    43021 aataagtgct gtaggcaaat aacggtaagt gatttttctt ttatcttgtt caaaagataa
    43081 aaagaaggaa ggataccctt caatcgctaa atcaatcagc gtgatttgga tagggataaa
    43141 cggaaatcca attgctgtaa cggcacatat aatcgataaa ataaatgaat aaatcgtttt
    43201 gataaaaaag atgcctgaga ctttcgtcac attgttgacc actcggcgtc cttcaaacag
    43261 gacttctggc aatgtagtaa aatcagagtc caacaatacc agattcgcaa tctgacgtgt
    43321 tgctccatca ccttctgcca tagcaatgct acaatctgct tctcttaacg ccaaaacatc
    43381 attcacaccg tcgcctgtca ttgcaaccgt tctgccgctt tctttcaatt catttaccag
    43441 caatttcttt tgctgaggac tcactcgtcc aaaaaccgta tagcgatgag cagcttctcg
    43501 cacttccatt tcttcagtaa tttgagaaag atcgacatac gcatcataat tcggtaatcc
    43561 tgcacgtcta gcgatattgg agacagtaaa aggattgtct ccagaaatca ctttcagatc
    43621 cacaccttcc tcatgaagat aagctagtgt ttcttgagcg ttttttcgga ttggatcatc
    43681 gatttcaaac agagcaaccg gctcaacaaa tgctggtttt tcttcgttca attgctgatt
    43741 tggagcgatc cctaacataa gtacgcgata gccattcgct tgggctgttt ttagactgtc
    43801 cggaagccga tcttcttcca ccaaacgttc aggcgctcct acgtacacga ctcccagttc
    43861 tggaaattcc atcgcgcccc atttgcgatc agaagaaaat gcgactttgt ttgtcacatc
    43921 ataccgatta gaaagctcaa aataatctct catagcccgc atagtgatgt tgttatcact
    43981 gctttctgcc agatacgtcc ccataatttc tgggatggct ttctcgtaca gcggatgtag
    44041 tgcttctacc cgctggatac tcatttttcc ttcagtaatg gtccctgttt tatccaagca
    44101 taatgtatcg acatgggcca gcgtttcaat tgaatacatg tcttgaacaa ggattcgttt
    44161 ttttgccagt ttggttaccc ctgtcgttaa tgcaatactt attagcaata ccaaaccctt
    44221 tggaagcatg cctaacaaag ctgctgcaga tgcaataaca gaaattttga tagaagcatc
    44281 gcggatgaac agtgcttcca aaaatagtat gatccccaaa ggaataatca cgaaactagt
    44341 gaatttggat actttgcgaa tcgaatctac aagttcagaa cgaatagctt tgtgagtctt
    44401 tgcctcgcta gtcaagcgga cagcataatt atctgcacct actcggataa cttcagccat
    44461 gacagaaccg cttgtcaaaa agcttccaga aagcaattca gctccagttt ctttgacaat
    44521 caaatcagat tcgcctgtca aaagagcttc atttgcttct gcccgtccag atataacctg
    44581 taaatcggct ggtatctgtt ctcctgctcc gatttttacc aaatctccta ataccagctc
    44641 tttagtagaa atcgattgtt ctttaccgtc ccggatcact agtacttctg attgggaaac
    44701 aatcgataat ttccgtacaa gatttcttgc atgtatttct tgataaattc caataacgat
    44761 attgacgaca ataattgcta aatacgccat gttggaatac gcacctacaa ataacagaca
    44821 aatcccaata ccaaagttca gaaaattgaa taacgtcaat atattatcgc tgaatatttg
    44881 ttttgtactt tttgatgcat cttcctggta gtcattttgc tggccagaag ccattttctg
    44941 aactacctct tgctgtgtaa gtccattcat tttctttttc tccattttcc gccaactttc
    45001 aaaaataatc acgtgtttaa gtctagcgtg ttccaagatt aaaaacaact tgtttttata
    45061 aaatttatag aaaaacacac gaatgatttt acaaaaaaga tgccaacctt tttgtttgaa
    45121 tcacccgtgt gctgttttta ttatcaatct atctttactt atattgttcc tccaaacggc
    45181 tcatccacca acctagtgct gtaccggcta taaaaagaac aggacaagct agtaccccag
    45241 caactcccaa tcccgcgtaa tcggtaggaa tgatcataat cgttgaagca aaaactacac
    45301 ctaaaatgaa atggaatagc ttgctatatg cctttgagaa aatgtaatcc atgatttttg
    45361 acaatccaag aacacaaaga atcccaccaa ttccgatcgg cacaatcact tcaagtcgta
    45421 cttctttaaa tccgtcagcc atcgctttat acaatcccat atacaccaaa aaattagaag
    45481 ggctcaatcc tgggacgatc atacccaaac caatcaatcc gccggcaatc agccatgttc
    45541 caaaattctg atcgacttgc ccgtcaaata attgagcgcc gtataataaa aacaaataag
    45601 ccagaacaaa agtaacaacc atgatgatca catcagaagt atctcttcct tttttccctg
    45661 cttctttcca taacgcagga acagttccag cgatacatcc gacaaaaaac cataatatcg
    45721 ttgtttcata cgcacctaat aaaaaactga ctaaaaaaga aagtagaaag atgcctgtca
    45781 ctccgcctag accaacaggc agaaaaaaca aaacattttc tttgaaattt tttgtaaggt
    45841 gggctaaaaa agaaatcagc cgctcataca tgccaaagac agctgctaat gcaccaccgc
    45901 tgactcctgg caagataaat cctgaaccga taaacattcc cttcacaaac cgtaacatcc
    45961 agtctttggt tgtgtacccc actttttgat tttccatttt ttgccttttt tccactattt
    46021 gcgcactcct tctttcattt aattttattc atgattgaac atttcctgct attttactta
    46081 aaaacttttt cataggtctc tattattttt tcattcattt tgacaatatc aggataaaac
    46141 atgttacctc cattatgata gagatagccg ccattgtaaa gcaaggactg gatccgccaa
    46201 tatcggtatt gtttcccttc ctcatttcct aaaagtgggc tcagcacatc tttagaatac
    46261 gcttctgcta attctactgt gttttctccg ccatgatttt ttacataggc aatataatct
    46321 ttcccaaaat tatatgcttg gacagctgtc cataaatcgc atccttgttt ctttgcttct
    46381 actatcattt ccgccaaata tttgacacct tgatcaatac tgtcagctgg attatcaatg
    46441 atctcagctt ctccatgcag actttccgag ctccgcatga gatctgtccc ttttcctttt
    46501 gattcggtca atattatcgc cttgatcaaa ttctcgtagt tttccatatg ataatttttt
    46561 gcagctgttg ttatttctat ttgatagctt tccactcgtt ttaccgaacg ataagttctt
    46621 cctcctaaaa acaacaccgc accaataacc gtcagaatga tcatgtaaaa aagaatacgg
    46681 ataatagata atcgttttcg cttcatttca tcacctagtt attttgacat ctttttttat
    46741 cttactattt ctttatcttc ttggctattt cttccttgat ttctgtgtac gccttaagaa
    46801 aaaatgaatt ttcctgtatt ttttgtcatc ttacgaaaat gatcgttgtt tttcagtaaa
    46861 aacaattgcc caatgactga tataatcgtt atactttaca cagtaggtga ttatgtgaaa
    46921 aaagaaaaga aatatgcaaa aatgccagat gggagcgaaa tttactatga aaagagcggt
    46981 caaggcttcc ctctcttttt actgcatggc aatgacggca gcggccgctt tttttcagaa
    47041 caggtccctg tactcgaacg ctactatacc gtgtatctag tagatagccg aggacatggt
    47101 cgttcgacaa acgaagcatc tatgttgaat tttcagttaa tggccgagga tctgaatacg
    47161 atcatgttgc tggaaaaaat cgatcaggca gattttcttg gatttagtga tggagcaaat
    47221 ctagcactgg tatttgccag cagcttccct aaaaaagttc atcgattgat tttaaattct
    47281 ggaaacacgc ttgttaaagg cgttcgtttt tctgccagag tcatcagtaa tattcattat
    47341 gcatgggtat ggttactctc tttatttcgc ccaagtcttc gcaaaaatct tttagttatc
    47401 aaacttttgc tgcatgacat cgggcttaca gaaaatgatt taaaaaaaat caactccccc
    47461 actttgatca tcgtgggaaa aaaagatgta atcaagctaa aacattcttt gtatatagct
    47521 aaaactatac caaaagcttc ctttgtgctt gtgaaagaac aaggacatga attagctaga
    47581 aaagatcctg aacgcttcaa tcgagaagtt cttcaatttc tttctgaaac ataactatta
    47641 ggaatagaag gtgatttatt tgttaaaaaa taccatacaa tggctgaaaa accacctagg
    47701 actgttcaaa acaatctttt tgatttctgt cattgtcatt attgtcggtg aattgatgtc
    47761 catcggtaaa actctatcta tccagcaatt aggagaaacg tttgccacta tacctgtatg
    47821 gaaaagcgga cttatgctgt tgattggtct tgtctctgtg ttacctatga ttggttatga
    47881 tattattttg aatcggatgc ttgaacaaaa gcagaatcct cgttacttgt ttgagacaag
    47941 ctggctgatc aatacaatca acaatattgc cggtttcggc gggtttgtta gtgtggggct
    48001 tcgctctgaa ctatatggac aaaagaaaga gagcagaaac gtgatccaag cattatcgaa
    48061 agttttcttg tttttgatgg ctggactttc tatttacagt ctgctttctt ttttacttgt
    48121 agtcttcacg ccagttgctc cttttttgaa gcaatattgg atatggttga tcggcggcgg
    48181 tctatatttt cctgtcgtct ttttatttac tactttcaaa aagaaaggat tccttggtgg
    48241 tacctcactt aaaactcaag gacagctatt gctagtttca ttgttggaat ggaccggtgt
    48301 cctgtttagt ttcctttctg ttggttattt aatggaaatc cggattgatc tgtggcaaac
    48361 aattccgtta ttcattgctg cttcagtgat aggaatcgtg tctatgattc caggagaaat
    48421 tgggagtttc gatgtaatga tgattatcgg gttgtccgct attggtgtgc caagagaaat
    48481 agtcgttgtg tggatcttgc tctatcgcct gttctactac atcattccgt ttttgattgg
    48541 aatcgtcttt ttcttcaaaa atatcggttc cacttttgat cagcgttatt ctggtatccc
    48601 taaacaatta gcaacagaaa ttgcgcataa aatcgtggtt gtcttattat acttttctgg
    48661 aatcatgcta gtactttctg ccactatccc gcaagctttt acagagtttc gctggcttca
    48721 tagtttgaac ccattgaaat ttcattttat tatccaattt cctagtatac tattgggatt
    48781 tcttttaatc attatgggca gagggatcgc agcacgtgtg aaacgagcat atttgcctac
    48841 aatcttcttg attgttctag ctttacttta tgttttatta agtgatttta gtttcacacc
    48901 ggtggttttc ttgtctattc tgcttctgat cattcttgct tctaaaaacg aattatttcg
    48961 ggaacaattg atctattcat gggagtggcg tacgatcgat ggaatcatta ttggtgcact
    49021 gtccttgctt tacatcgtta ttggggtata caatctgccg gatttccctc atcggcgtca
    49081 ccattttatt tcctttttct tatttccttc tgaaaagatt tggttttcgg gattgttggc
    49141 catcatcgct gttagtttca tgatcgttct atttgttcat ttccttcaag gagaaaagaa
    49201 acagattggc gaagccttta atgaagaaaa ggccctgaag atccttacaa cttatggagg
    49261 aaactccgat agtcaattga tcttcttaaa agataagcgg atgtttgcct atgaaaaaga
    49321 cggtgaacca actgttcttc tccaattcgc ttgcttcaat aataaatgta ttgtaatggg
    49381 tgatccttct ggtaagaaag aagattttcc agaagcaatc gaagctttta tcgaagaaac
    49441 agatcgacta tgctatttac cagttttcta cgaaacaagc gaagagattg ttatgatttt
    49501 gcatgaattc ggctacgatt tcattaagat gggggaagaa gcttatgtag acctgaatag
    49561 ttttacaact tcagggaaaa aaatgaaggg cactcgtgct gtcttgaatc ggatcgaacg
    49621 agaaggattt acatttgatg tcttacaacc accattttct actgagcaaa tgagtacttt
    49681 caaaaatatc tctgataatt ggttgggttc acgaaaggaa aaagggtttt ctttaggctt
    49741 tttctctgaa gattatctac aaagagcgcc tattgcagtt gtcaaaaata cccaagaaga
    49801 aattgtcgct tttgcaacga tcatgcctac ttacacgaac aataaagtag gaacgattga
    49861 tctgatgcga tatgatccta aaaaagcacc ttctggcagt atggatttct tgttcttgca
    49921 tttgtttgcc tatatgaaag aagaacatat ccaatggttc aatttaggga tggcccctct
    49981 ttcaaatgtc ggaacttcca gaaagagttt tttacaggaa aggattgcat acttggttta
    50041 cgagtttggt tctcattttt attctttcca tggattaaga gaatataaaa gcaagtacgc
    50101 tacaaactgg gtctcacgtt atactctata ttctagagat agttggattg catatgttat
    50161 gattgctttg ctgattattg ataatgcgcc agttgagcag acacaaggta gaataagtgg
    50221 tttgaaaaaa tggatacgaa gaaagtatta aaaactgcat accgatagat gaacactctc
    50281 atgatgaata aaagagactg aagtaaaacg aaagttcatg cttctacaat ctcttcttat
    50341 acaattgaag aacaaagagc ggtccaaaca gaaatcctgt ttggaccgct cttttatttt
    50401 aaacattttt cattaccaaa atattcgagt cgcgtttctt atgcttcgat ctctgtaacg
    50461 atacctgaac ccactgtccg tccgccttca cgaattgaga atgtcgttcc gttttcaaca
    50521 gcgattggat ggatcaagtc aacatcaatc gtcacgttgt caccaggcat gaccatttct
    50581 gtatcttctg gcaatgtgat tgttcctgta acatcagttg tgcggaagta gaattgtgga
    50641 cgatagttgt tgaagaatgg agtatgacgt ccaccttctt cttttgtcaa cacgtacact
    50701 tctgctttga attttgtatg tggagtaatg gaacctggtt tagcaagcac ttgtccacgt
    50761 tcgatatcgt cacgttggat cccccgtaac aacacgccta cgttatcccc agcttccccg
    50821 taatctaacg ttttacggaa catttctaca cctgttacaa ctgctttttg tgtttcaggt
    50881 ttgatcccta cgatctctac ctcatcaccg acacgaacag caccacgatc aatacgacct
    50941 gaggcaacag ttcctcgacc tgtaattgag aagacgtctt ccactggcaa tagtaatggt
    51001 ttatctgtat cacgttctgg tgttgggata tattcatcta ctgtatccat caattccata
    51061 atagcagctt cagcatctgg atcgccttgc aatgctttta atgcggaacc tttgatcaca
    51121 ggagtgtcat cgcctgggaa accatattcg ctcaataact cgcgaacttc catttctacc
    51181 aaatcgatca attcttcatc atcgactaaa tcaactttgt tcaagaaaac aatcaggtat
    51241 tttacaccaa cttggcgtga caataaaatg tgttcacgtg tttgaggcat cggaccgtca
    51301 gttgcagaaa caactaagat tgcaccatcc atttgtgctg cccctgtaat catgtttttc
    51361 acatagtccg cgtgtcctgg tgcatcaata tgcgcgtagt ggcgtttttc tgtttcatat
    51421 tctacgtgtg cggtattgat cgtaatccca cgttcacgtt cttctggagc tgcatcaata
    51481 ctagcatagt cttgaggatt tgctaggcct tttttgccta atactgtagt gatcgcagca
    51541 gttaaagtag ttttcccatg gtcaacgtgt ccaatcgtac caatgttaac gtgtggttta
    51601 cttctgtcat aatgttcttt tgccataatt tacaaacctc ctaaataata tagatcactg
    51661 aaaaatttca gctctcacct ttttattata gtcttttttt gactaaatca aaaagaatac
    51721 gtccgactta ctttttgtaa gattcgaact aagcttatta tacgtcaata ttggtcaaag
    51781 tcaactaaga gcactcgctt gtcttatacg cgaaaaaagt accttttata aataaaaaaa
    51841 tgtgtttttt gagaaaaact tcaagatagt ccttaacttt cttttgaagc aataagaaca
    51901 aaatgaggaa aagtttaaaa ttcagctgtt gccaacaact ttcaatagac gaaatcttct
    51961 atttcgttaa taataaggaa agaggtgaag tacatgaaaa aattaattgg cgtacttgtc
    52021 gttttaggca tatttctcgg cggaagtttt gcagcttatc attattttta cggcggcgaa
    52081 gcttattata caaaaatcac gacgaatggc gaaatgtcag ctacccaagc agataacgga
    52141 gagaaattca cgacttatac ctacaagcaa gcggcttata ataaagatgg tgaaaaaaaa
    52201 caggtgacgc ttcgcgaaga aagagaacat ccattaaaga tgaatgcgta tcttaaactc
    52261 aaagtcaatc ctcgtaaagg tgtattaagc tgggaagaaa taaaggcttc tgaagtgcct
    52321 aaaaatgcgg cagaaaaaat cgataattag taaatggtct taaaatttta ttagataaaa
//
LOCUS       DAKCAA010000012        50338 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000012 DAKCAA010000000
VERSION     DAKCAA010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 50338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.012"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(87..266)
                     /gene="rpmF"
                     /locus_tag="OUE31_000828"
     CDS             complement(87..266)
                     /gene="rpmF"
                     /locus_tag="OUE31_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCU0221858.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(324..893)
                     /locus_tag="OUE31_000829"
     CDS             complement(324..893)
                     /locus_tag="OUE31_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HCU0221859.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1079..1981
                     /locus_tag="OUE31_000830"
     CDS             1079..1981
                     /locus_tag="OUE31_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCU0221860.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2016..3800)
                     /gene="pyk"
                     /locus_tag="OUE31_000831"
     CDS             complement(2016..3800)
                     /gene="pyk"
                     /locus_tag="OUE31_000831"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HCU0221861.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3874..4836)
                     /gene="pfkA"
                     /locus_tag="OUE31_000832"
     CDS             complement(3874..4836)
                     /gene="pfkA"
                     /locus_tag="OUE31_000832"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HCU0221862.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5004..8318)
                     /gene="dnaE"
                     /locus_tag="OUE31_000833"
     CDS             complement(5004..8318)
                     /gene="dnaE"
                     /locus_tag="OUE31_000833"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HCU0221863.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8549..8734
                     /locus_tag="OUE31_000834"
     CDS             8549..8734
                     /locus_tag="OUE31_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HCU0221864.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8796..9992)
                     /locus_tag="OUE31_000835"
     CDS             complement(8796..9992)
                     /locus_tag="OUE31_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCU0221865.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10162..11598)
                     /locus_tag="OUE31_000836"
     CDS             complement(10162..11598)
                     /locus_tag="OUE31_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCU0221866.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11891..12700
                     /locus_tag="OUE31_000837"
     CDS             11891..12700
                     /locus_tag="OUE31_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCU0221867.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12886..15039)
                     /locus_tag="OUE31_000838"
     CDS             complement(12886..15039)
                     /locus_tag="OUE31_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCU0221868.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(15333..16181)
                     /locus_tag="OUE31_000839"
     CDS             complement(15333..16181)
                     /locus_tag="OUE31_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCU0221869.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(16405..18345)
                     /gene="thrS"
                     /locus_tag="OUE31_000840"
     CDS             complement(16405..18345)
                     /gene="thrS"
                     /locus_tag="OUE31_000840"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HCU0221870.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(18682..18861)
                     /locus_tag="OUE31_000841"
     CDS             complement(18682..18861)
                     /locus_tag="OUE31_000841"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HCU0221871.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(18908..20731)
                     /gene="cadA"
                     /locus_tag="OUE31_000842"
     CDS             complement(18908..20731)
                     /gene="cadA"
                     /locus_tag="OUE31_000842"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCU0221872.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            21009..23288
                     /locus_tag="OUE31_000843"
     CDS             21009..23288
                     /locus_tag="OUE31_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCU0221873.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(23381..24028)
                     /locus_tag="OUE31_000844"
     CDS             complement(23381..24028)
                     /locus_tag="OUE31_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221874.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(24207..24926)
                     /locus_tag="OUE31_000845"
     CDS             complement(24207..24926)
                     /locus_tag="OUE31_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0221875.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(25057..26208)
                     /locus_tag="OUE31_000846"
     CDS             complement(25057..26208)
                     /locus_tag="OUE31_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HCU0221876.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(26425..27165)
                     /locus_tag="OUE31_000847"
     CDS             complement(26425..27165)
                     /locus_tag="OUE31_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCU0221877.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(27169..27492)
                     /gene="rsfS"
                     /locus_tag="OUE31_000848"
     CDS             complement(27169..27492)
                     /gene="rsfS"
                     /locus_tag="OUE31_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HCU0221878.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(27549..28142)
                     /gene="yqeK"
                     /locus_tag="OUE31_000849"
     CDS             complement(27549..28142)
                     /gene="yqeK"
                     /locus_tag="OUE31_000849"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HCU0221879.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(28126..28776)
                     /locus_tag="OUE31_000850"
     CDS             complement(28126..28776)
                     /locus_tag="OUE31_000850"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HCU0221880.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(28786..29097)
                     /gene="yhbY"
                     /locus_tag="OUE31_000851"
     CDS             complement(28786..29097)
                     /gene="yhbY"
                     /locus_tag="OUE31_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HCU0221881.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(29113..30222)
                     /gene="yqeH"
                     /locus_tag="OUE31_000852"
     CDS             complement(29113..30222)
                     /gene="yqeH"
                     /locus_tag="OUE31_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HCU0221882.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(30219..30746)
                     /locus_tag="OUE31_000853"
     CDS             complement(30219..30746)
                     /locus_tag="OUE31_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HCU0221883.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(30926..31711)
                     /locus_tag="OUE31_000854"
     CDS             complement(30926..31711)
                     /locus_tag="OUE31_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HCU0221884.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(31704..32573)
                     /locus_tag="OUE31_000855"
     CDS             complement(31704..32573)
                     /locus_tag="OUE31_000855"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HCU0221885.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(32574..33953)
                     /locus_tag="OUE31_000856"
     CDS             complement(32574..33953)
                     /locus_tag="OUE31_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HCU0221886.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(33961..34380)
                     /gene="fabZ"
                     /locus_tag="OUE31_000857"
     CDS             complement(33961..34380)
                     /gene="fabZ"
                     /locus_tag="OUE31_000857"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCU0221887.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(34405..34881)
                     /gene="accB"
                     /locus_tag="OUE31_000858"
     CDS             complement(34405..34881)
                     /gene="accB"
                     /locus_tag="OUE31_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HCU0221888.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(34884..36119)
                     /gene="fabF"
                     /locus_tag="OUE31_000859"
     CDS             complement(34884..36119)
                     /gene="fabF"
                     /locus_tag="OUE31_000859"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HCU0221889.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(36138..36875)
                     /gene="fabG"
                     /locus_tag="OUE31_000860"
     CDS             complement(36138..36875)
                     /gene="fabG"
                     /locus_tag="OUE31_000860"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HCU0221890.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(36887..37804)
                     /gene="fabD"
                     /locus_tag="OUE31_000861"
     CDS             complement(36887..37804)
                     /gene="fabD"
                     /locus_tag="OUE31_000861"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCU0221891.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(37911..38135)
                     /locus_tag="OUE31_000862"
     CDS             complement(37911..38135)
                     /locus_tag="OUE31_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCU0221892.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(38188..39150)
                     /locus_tag="OUE31_000863"
     CDS             complement(38188..39150)
                     /locus_tag="OUE31_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HCU0221893.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(39160..39600)
                     /locus_tag="OUE31_000864"
     CDS             complement(39160..39600)
                     /locus_tag="OUE31_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCU0221894.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            39906..40871
                     /locus_tag="OUE31_000865"
     CDS             39906..40871
                     /locus_tag="OUE31_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCU0221895.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(40928..41158)
                     /locus_tag="OUE31_000866"
     CDS             complement(40928..41158)
                     /locus_tag="OUE31_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HCU0221896.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(41244..42131)
                     /locus_tag="OUE31_000867"
     CDS             complement(41244..42131)
                     /locus_tag="OUE31_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCU0221897.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(42220..43443)
                     /locus_tag="OUE31_000868"
     CDS             complement(42220..43443)
                     /locus_tag="OUE31_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCU0221898.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(43460..44506)
                     /locus_tag="OUE31_000869"
     CDS             complement(43460..44506)
                     /locus_tag="OUE31_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCU0221899.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(44670..46397)
                     /gene="ptsP"
                     /locus_tag="OUE31_000870"
     CDS             complement(44670..46397)
                     /gene="ptsP"
                     /locus_tag="OUE31_000870"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HCU0221900.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(46397..46663)
                     /locus_tag="OUE31_000871"
     CDS             complement(46397..46663)
                     /locus_tag="OUE31_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HCU0221901.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            47142..49376
                     /locus_tag="OUE31_000872"
     CDS             47142..49376
                     /locus_tag="OUE31_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCU0221902.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            49524..49844
                     /locus_tag="OUE31_000873"
     CDS             49524..49844
                     /locus_tag="OUE31_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCU0221903.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(50049..50273)
                     /locus_tag="OUE31_000874"
     CDS             complement(50049..50273)
                     /locus_tag="OUE31_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HCU0221904.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
BASE COUNT        14352 a        10802 c         8782 g        16402 t
ORIGIN      
        1 atatttttta tttaccgact acaaaaaaat aaacctcaag gctccatggt tagccttgag
       61 gttttacatt ttctaattaa aatgtattaa gcttcttttg acattacgtc cttaccatca
      121 tagtaaccac aatttgcaca tacgtgatgg ctttttttca tttcaccaca gtttggacat
      181 tcgtttaacc ctttgattgt caatttgtag tgtgtacgac gttttgcttt tttagctttt
      241 gatgttcttc tagctggtac tgccattttg ctacacctcc ttgtaaagtc ttgtatctaa
      301 attagacaca atatattcca atcttacttg ttatcgtcgt cttttgattt agaatcaaaa
      361 agttcagata gttttgcaag acgaggatca attttattct cggcttcttc catttttctg
      421 cgctggtatt cttcttcgga aacaacttcc caatcattgc cttttggaag ttctgttgct
      481 gcttcctctt cttttgtcaa tacccgcatt ggaatcgcca ataagatgtt gtcttcaatc
      541 gactctgcta aattcaataa tggaccttca attagcaaaa tctcatctgc agacatttgt
      601 tcatctctac tttggaattg ttcttctgtc atgaatactt cgtctacaga aaaatccatg
      661 ggcagttcaa caggttctag tgaacgtgtt gaaggaactg tcaaagtcgt ctgcacagtg
      721 taatgaacga tatagccttt cttatcaact gagaccaaac cttcgacttc cactggcgca
      781 acatcaagta ttaaattgtc tcgcttcatg agagcggctt tcaagtcgag cgtctcatga
      841 aaagttaacg gtgtctcctg gtattttctc aattccaata aagaccattt catttttcat
      901 cactcctaag caacaaaagc aattatacag ggcaaaaagc atgttgtcaa tgaaattttc
      961 ttgacacctt gcagttcata aaaaaacaga aaaatcttta ttagaaagcc tctgtttgct
     1021 atcatcctca gaatcattta caataatcat tattccatta aaggagcgga tgatcttcat
     1081 gaacacgaaa gatatcgaat actatgtcca aatcgtcaaa caaaaaaatt ttacgaaagt
     1141 ggctaattat ttccgtgtga gccaacctac tattacatat gcattacaac gtcttgaaaa
     1201 agagtttgac accgtactta ttacaagaga tcgatcgcat cacgaattaa tcgtcacgcc
     1261 ttctggaaag cagctgtttc tccatgcaca aaccattctc caagagattt ctactgcaag
     1321 agctgaaatc actcagttgc aaaagaaaaa gcttcgtttt ggcatgcctc ctattatcgg
     1381 caatgaatac tttcctaaac tgtcaagtta ctttatcaag catgaattga tgaatcaaat
     1441 tgagattacc gatggaggct ctcgggactt atacgggatg atccgacaag ggaggatcga
     1501 tttagctgta ttaggctcaa cacagccaat cgtggatcaa tatttagaaa cagagttact
     1561 tttggacaaa cgtttcatga tcgtcgtgcc acctacacat cctctttcca agcaggatac
     1621 tgtctctttc aaagatatag cagatgaaca gtttgtacta ttgaacgaac attatgtcca
     1681 ccccgcagca ttcactaagc tttctaaaca aacacatact catccaaaag ttgtttatca
     1741 aagcaatgac ttgacgattt taaagagtat ggtccgagaa aatgtgggta tcggtttttt
     1801 ggcagagatt gctgtccatc ctgaagatca tttagtttgc ctccctcttt cagatgaagt
     1861 tcagcctcgc ttcttgattt cattggcaaa acgaacacag cagatcgtca cgcctcttca
     1921 agaacaagta gtccaagtta tccatgaatt cgttacagca caaaaaaaca gctcttcgta
     1981 aaagaagagc tgtttttatt ttttattaag ctaaattaga tagctgttgt ttcgccacgg
     2041 taaacgatgc cgcgacgtga atcaacggta atcaattcac cttctgtaat tgttgttgtt
     2101 gcgcctttag caccaacgat tacaggaata tcttgtgcaa ttcctacaac tgcagcgtga
     2161 gaagtcaatc cgccttcttc aacgataaca gcagctgctt tttcgattgc aggcatatat
     2221 tctttgtcag ttgatggtac aactagaacc attccgtctt ttgctttttt tacagcttct
     2281 tcagcagatg aagcaataac tgcatttgca acgacagatt tttgtccaac gccttgagct
     2341 tctaataatt tagaaccaat catttgaatt ttcatcacgt tagttgttcc gcgttcacca
     2401 actggtacac cagcagtgat caagattaaa tcgccttctg atgcgaaacc taattcaaca
     2461 gcttttttag ctgctagttc aaacatttca tcagttgttg atggtttttc agcaactgtt
     2521 gggtaaacgc cccagtttaa catcaaacca cgttttgtgc gttcgtcaaa agtaacagcc
     2581 aagatatctg catctggacg atattttgaa atcatttttg cagtgtatcc tgattcagtt
     2641 gcagcaacga ttgttttcac gcctagattt tttgcagcac gagctacaga taaaccgatt
     2701 gtttcagtta catctgtttt atcgaattcg ttcaattgga atgtacctaa ttctgataat
     2761 gcattttcag cttcttggtc gatacgtgcc attgttgaaa cagcttcaac tgggtagtcc
     2821 ccgtttgcag attcaccaga tagcattgtt gcatctgtgc catcaaatac agcgttagca
     2881 acgtcagaag cttccgcacg tgttggacgt gggttttctt gcattgattc taacatttgt
     2941 gtagcagtga taactgggat accagcagca ttacattttt tgataatgcg tttttgaacc
     3001 attggtacta gttcagctgg gatttcaaca cccatatctc cgcgggcaat cataacaccg
     3061 tcagaaactt tgatgatttc gtcaatgttg tcgatacctt cttgagattc gattttaggg
     3121 aagatttgaa catgagtcat gtctttttct tctaagattt cgcggatatc tagaacgtct
     3181 tgtgctttac gtacaaaact tgcagcgata aagtcgatat cgttgtctaa accaaaacga
     3241 atatcgtcag catcttttgg agtaatacct ggcaaactaa tagaaacgcc tggtgcattt
     3301 acccctttac gtgatcctag catacctgca tttttaactt ctacgactaa ttcacggttt
     3361 gcttcgtctt tttcaatgat ttgcatatcg atcaaaccat catcaaataa aatgtgtccg
     3421 ccaacgtgaa catcgtcaaa taatcctggg taagtaaccg cgattttttc ttttgaacct
     3481 acatgttcag gatccataga gatgcgtgtt tgatctccta cttcaaattt gatgtatcct
     3541 gcacgaccaa aatcagcttc tgttgtgcct tgaacagttg tacggatttc agctcctttt
     3601 gtatctaaaa gaataccgac atcttttcct gtctttttaa ctgcttcacg gaccatagtc
     3661 atacgtgata attgttcttc atggtcacca tgagaaaaat taaagcggaa gacatttgcc
     3721 ccagattcaa tcaattgaga aataatttct actgagttac ttgctggtcc taatgtacta
     3781 acgattttgg tttttttcat ttaaaaaact ctcccattca attttgttta tttaaagctg
     3841 tacacagctt aaatagcttg gtttctttca ctcttaaaat gaaagtgaat tatttagatc
     3901 atatagtgat aagtctggtt tatgtttgtt gttttcaagt gtatcaatga tgtcagacgc
     3961 aacgatttcg ttgtcatgga taccgacaca taatccacct tttccttctt gaagcaattc
     4021 gacagcgtaa gcaccgaatt tacttgccaa cacgcggtcg cgtgcgcttg gtgctccacc
     4081 acggacaacg tgtcccaaga tagatacacg tgtatgatag tcaccaaatt ctgaaagttt
     4141 ctcagcgaat tcatttccgc ccattacacc ttcagccaag atgatcaagc aatgtttctt
     4201 cccgcgatcg cggccttctt ggattttttt agcaactgaa gccatatcaa aatcatgttc
     4261 tgggatgatg atttcatccg ctccgccagc cacacctgac cataaagcga tgtctcctgc
     4321 attgcgtccc attacttcga taacgaatgt acgaacatga gaagtcgctg tgtcacgaat
     4381 acggtcaatt gattctagta ctgtattgat tgctgtatca aaaccgattg tgaaatcagt
     4441 cccaggaata tcattatcga ttgttccagg aatacctact gctgggaaac cgcgttttgt
     4501 caaagccatt gcgccatgat aagagccgtc tcctccgata accactagac cttcgattcc
     4561 gaattttttc aattgttcga ttccttttaa ttgaccttct tcagttgcaa attctggata
     4621 acgtgcagaa tacaagaatg taccaccacg ttggatcttg tcacctacat ctgccacatc
     4681 aagacgacga atatctccag caactaaacc ggcaaaacca taattgatcc cgtatacttc
     4741 cagtccttcg taaatacctt tacgaacaac ggcacgaaca gctgcattca ttccaggtgc
     4801 gtctccgcca ctggtcaaaa ttccgatgcg tttcataata aacattcacc tcattaaaat
     4861 actttatcct aagtatgact taggtttaca accatttttg cgttaaccac gactaacatt
     4921 ctaacattat ttttctcact tgtcttgatt tacggataaa aaaatgaaaa aaaatgaaag
     4981 caagtagtat tttttaccgt aagttatttg aaaaccacat tatcttcgcc aagcagataa
     5041 ataagttgcc cctttatact cttgctgtca tccacccaat aagcatctga cagaactact
     5101 tttcgttgcg ttttttcgtg atacataact actggtatat atcctgggtg tttctgaaaa
     5161 atcacttgta attgtttcat tatctcggga tcttcccgtt cttctgtaat acgcaaatag
     5221 caagtttgtg aaggatactg ggcttctaac tggttaggat cagcaaagct ttctccaatt
     5281 agttgcagtt cctgattata tttgctgatt tcgctccgcc cttgaacaaa gatcactcga
     5341 tcaacggcaa acaaattacg atatttacga taaagagttg gaaaaactgt gacagaaatt
     5401 tctccactac tgtcggttcc ttcaacaaag gccatcagtt ctcctttttt tgtccgaatt
     5461 tctctaactt ccttgatcat cactaataaa ttgactggtt gattagggac gatatctgta
     5521 atcagctgaa cttgtttagc taaacgaaga cgatcaaacc cttctgcagg atgacctgac
     5581 aaataaatac ctaagtactc ctcttccagc ttcaagcgtt cttctagtgt atagtcagcg
     5641 acttcttctt cttttaatgc catgattccc agcaagtcaa gacttccacc actgtaaacg
     5701 atattttgga tttttccttc gagatcaagc atcaattgtt tcctgttagg agataattca
     5761 tcaaaaactc ctactgctgt cagtgattgc agtaactcta atttcagcca acgcttatcg
     5821 atccgtatga ggaattgatc cactgactgg aacgggccat tttgttttct ttcgtttaat
     5881 atatcttcta caaaatcacg ccgaatacct tttatcgctg tcagtccgaa tctgatttct
     5941 tccttattga ccaactcaaa actggaatta ctttgattaa tggacggcga ggaaagtttg
     6001 agtttatttt tacgtgcttc tgcaatatat tctttcaatt ttgatgtgtt atgccgaaca
     6061 gaattcatca ggctggtaaa gaaagcacct ggatgatggg cttttagata cgccatttgg
     6121 aatcccacga atgaataagc aaatgcatgt gaccgattga atccatagtt tgcaaatttt
     6181 tcgatatatt catatacggt cgctgctgtt ttttccgaat atccctgttg taatgctcct
     6241 gatacaaaat gcgacttttc ttcatctaat acgtcttttt tctttttact cactgcccgt
     6301 cgcagaatat ctgactgccc taatgtaaat ccagccatag tcgaggcgat ctgcatgatt
     6361 tgttcctgat agacgatcac tccatatgtg tttttcaaaa tcgggatcag tgaatcatct
     6421 gggtagcgaa tggcttcttt tcctttcttc ctggcaatga aggtatctat attttgcata
     6481 gggcctggtc gatacaatgc attgactgcg gcaatatctt cgatgttttc tggatctaat
     6541 cttcgtaaaa cgttccggat accagcagat tcaaattgaa atactcctga ggtttcgcct
     6601 cgttgaaaca agagcagcgt ttttgcatca tttagcggga tctcttttaa tcggatctca
     6661 tacccttcta ctcgcttaac agctttcaaa gtaaaatcaa taatcgataa gttgcgtagt
     6721 cctaaaaagt ccattttcaa aagaccgatt gcttctacct cattcatcgt atactgggtc
     6781 agaaaagctt catcagaacc gcgttggagc ggaactagtt caagtagatt cttatcgctg
     6841 ataactacac ctgctgcgtg agtcgaaaca tgtcttggca atccttctaa aatcactgca
     6901 gttttgaata aaagttggtt tttttcgctt gcctgaacta attctactaa ttgatgcgaa
     6961 gttttataag cttgggtcaa tgtgattttc aattgattgg gtattgcttt tgaccagcgg
     7021 tttgcttcac tttgcgataa accaaacact ctagctgcat ctctaagaac catttttgct
     7081 gccattgtgc caaatgttgc gatttgtgcc atatgatatt gtccatactt ttctcgaaca
     7141 taattcaata cttcttcacg tcgattgtca ggaatatcca aatcgatatc tggcatcgta
     7201 aagcgttcgg ggtttaaaaa gcgttcgaac agcaaatcat attctaatgg atccacatct
     7261 gtgatttcta acacataggc tactaatgaa cccgcagcag aaccacgacc tgcaccggta
     7321 acgattttgt ttctatgagc aaaagccatt acatcccata cgatcaagaa ataatcatcg
     7381 aatcccattt gatggatgac agataactcg tagtccaaac gttcttggta ttcctttgta
     7441 tagtcagtga ttcggcgttc cacttgcgaa tagcataact ctcttaaata ttctccagct
     7501 tgttttccat taggaactgg ataatgcgga agtaatttct gatggaactg gaattcaaat
     7561 gaaatcgatt cagctaaacg ctgggcgcct attacagctt gggaaagacc cgctttttcg
     7621 aatcgtttga tcatttcttg ttctgaaaga agatagacat ttgctgttag tggtaaagat
     7681 gcagataaat tttctaaagg tatttggctt ccctctttga tatgtttcat cacttcaagt
     7741 gcaaaaagtt cttcttgttg taaactagcg atgggatgta atgcacaaag cgaataattt
     7801 tcttttatca catactgata ccattcaggc aattgatcag gcgtgttttc tgtcaagccg
     7861 atataaaaat ttctagtaaa aacattttca agtaaaaact gccaatgacc gaaaaagtta
     7921 tcctctttat tgaaagcctc agaaacagaa tgatttgccg gaacaacaaa cgctagatgg
     7981 tcggtttctg tcatttctgc aagttccaat ttttcttgga tcatttttcg gctggaaagt
     8041 ttcatcagct gctgataacc tatttcatct tttgcgtacg caagcaagcc ataatttttt
     8101 tcttcataag tataactaag atgtaatcca atgattggct gtactccttc ttctacacaa
     8161 atacgataga attcaggtgc accgtataag acatctttat ccgttatggc taatgaagtg
     8221 tagccttgtt tttttgcttc ttgtacatat tctcgaatac gtatcgtact ttgtaaaaga
     8281 gaataagaag taattgtata aagttgtggg aaaaacatct tgcattccgc cttttttttc
     8341 gttaaaattc actagcgtta aaaggtttga tccttttact ttcattaaga tagcaggcgc
     8401 tgaagttgat tattccactt catttgcttg cttgtaatct gtaggaatga gttctttcgc
     8461 aagaactcaa attttattga gatttggtct cgtttcttta cattcaaaga aaatctggta
     8521 aaattaagat agaaaagagg tgttctttat gcgatatatc gttacattat tctgggctgt
     8581 cgttctaggt caagtagtcg gttatattgg tgctgcatta acaagcggaa catatgattt
     8641 tactttgaca acaatcattt cattcattgc gggtgtcatt atccttttga ttggtgcagt
     8701 tgcgccaaga aaagaaacct ctgcccattc gtaaaaaaac agccaagagc ttgagatttc
     8761 tcaagctctt ttttattttc tactcctcac caccattata atctgctgcg aagaacttta
     8821 cgaaagttga ataaagaaag aagaatattt gacagaacaa acaaacttgt cacaataaaa
     8881 acagcactgt aattataagc atgcgcgact gtcgatccta gcatgggacc taaaacttgt
     8941 ccaaagttgc taaacatctg attgtagcta tagattcggc tgactccttc ttgaggcgta
     9001 atcttactga tcagtgtatt gacagaaggc atcaaagcgc cagttgaaaa gcctaaaata
     9061 aagcgaagta tacctaattg gagcggtgta gtgacgaatg ccataggtaa ataacagcaa
     9121 aatgataaaa tgagtcctcc aattagaact ttttgattcc caatcttatc ccctagtttt
     9181 cctagtttcg gtgaagaaaa gacagcggaa acaccagcta tcgaaacaat caagccgctg
     9241 acaaaaagga tattttctgt acttccgctc aattcacgaa tatataaggt caaaataggg
     9301 ctgatcgtag tgattcctat ctgtaaaatc aaggtcgtaa tgaagagacc gatcaaaata
     9361 gagagatgat ccatttttga aaaaatttct ttggtgctta tcagatcttt tttctcgatt
     9421 ggatggaaat cttctttgac taagaaaatg gtcaataccg ttgtgatcat caacaaagcc
     9481 cctgtgatca agaatacatt ttccatacca aaccactgag ccagtgcacc gcccattgaa
     9541 ggtccgatca gatttccagc aatcgctccg gtagacaatg ttcctaacgc ccatccgctc
     9601 ttttctctag gtgcctgtga agcaatcatc gctgtggcat ttggaatata tccagacaaa
     9661 atcccattcc aaaaccgcat gatcaaaagc caatacgcgt ttggtacaaa agccaaagat
     9721 cccattgtta atgtcatccc tgctgctgca cggatcatca tgagttttcg gccttttcga
     9781 tcagctagat ttccccagat tggtgcaacc acggcagatg caaaagcagt cacagagatt
     9841 gctagtcccg aaaacaattc gatttgatct tttggtgttc ctagttgctc aacataaact
     9901 ggtatgaatg gcataactaa actaatactt gcaccagtga aaaaacagcc aatccacgca
     9961 atcactaaat tttttctcca attaatctcc atctatcatc cctctttcgt ctcttttatc
    10021 atacctattt tcgaataaac aagcaacgat ctcgccagta aaaagagaaa aatcccgcaa
    10081 aggtcatttt atatgtaacg ttctttttat gtaaaacaaa aagagatcag aacaaatact
    10141 gttccaatcc cttctcttta gttaaattgt tgctagaatg atgaagttga taatgaataa
    10201 aatatcaacg atccacaaag caacagaaac ttgattgtat tttcctttga ttactttcac
    10261 aattgtatag aaaataaatc ctgctgcaat cccataggaa atgctatagc acaatcccat
    10321 aaagatcgat gcaaagaagg ccggtaaagc ttcttccata tctagccatt tgatgtctgc
    10381 aaaagaagcc atcatcatta ctccaactaa aatcaatgct ggcgcagttg cttgatttgg
    10441 tacaatggcg atcagtggag agaataaact acttaatgcg aatagcactg ccactactac
    10501 tgaagtcaaa ccagtacgtc caccggcccc gatcccagct gcagattcga cataagttgt
    10561 tgtattcgat gtaccaaaga tagcccccac agaagtagcg atcgcatcgg caaatagtgc
    10621 tttatccatt tttgttttga acccacgacc atcttccaac gcgatctcgt cttcttttga
    10681 gaaaatacct gtgcggcgtc ctgtaccgat aaatgttccg atcgtatcga aagtatcaga
    10741 taaactgaat gcgatgatcg tcatcaatac ttgaggaatc ttggaagaat cactgaataa
    10801 agattgcatg ccttcagaac caaatgctgc accgaaagtt gttcctaatt ctttaaatga
    10861 attacctaac gaattcgttt gccaatcaat ggaacttaaa tcaacaacac ccataaaaat
    10921 accaaggact gtggtcgcta cgataccgat aagaatagcc ccacggacat tttttacaac
    10981 taaaatggct gtcagtacca aaccaatcac agccaataag ataggagcgt tgtcaaagtt
    11041 ggctaacgca gggacgattc caccatttat cgtaacattt gtcgcttttc cgccttcaac
    11101 gacagagctc gaaatagctg actggtctgc tgaaaaagat aagaatcctg catttttgat
    11161 tccgacatac gcaacgaaaa taccgatccc gccaccaatc gcatgttgaa gactttcggg
    11221 aatcgcccga ataatcattt ttcgaatatt tgtgacagta ataaaaatat tgattaatcc
    11281 gcaaataaac accattgcca aggcttgttg ccaagaataa ccaagcccaa aaacgaccgt
    11341 aaaagtgaaa aatgcgttca atcccatacc aggtgcctga gcatatggta catttgcgaa
    11401 caatcccatt accagcgtac caataatcga tgcaatgatt gtcgctagaa atactgcttg
    11461 gaagggcata cctgatgctg acaaaatcgt cggatttacg aataagatat aactcatggc
    11521 aaagaatgtc gttactcccg ccattatttc agttgataca tttgtattgt ttttctttaa
    11581 accgaaaaac ttttccataa aaagttccac tccctgaatt tttttctgat ggaaaactat
    11641 aataataaaa aataagtaaa atagggcaaa tccatcgaac aatttcaaat tatatagacg
    11701 tttcattcgc ttttcaacgt ttttttaaca aaaaaagcga aaataatact taacgttcgt
    11761 gtttagctta tgtttagcta tttatatagc cataactgta gtttttgtta ggaatagctg
    11821 attgctcttg ttaattacct aaaatatgct agactaaaac aaatgctagt tgaggaagga
    11881 aggaccctta ttgaataaaa aattaattgc catcgatctg gacggaacta ccctcaatca
    11941 agattcgatg attacatcta aaacaaaaga gactctaaaa aaagcaatca atgccggtca
    12001 tcatgtcagt attgctacag gacgcccatt ccgaatgagc catcagtttt accaacaatt
    12061 agaattaaca acaccgatgg ttaattttaa cggcgcatta gtacacatcc ctaatcagca
    12121 ctgggatggt gaaagagaaa cgttgatcaa tcgtgaaatc gcttttgaaa tcttatcgca
    12181 aaaaaagcag ctaaatttag attttatcgc tgctgaaaat cgtgatactt tttttattga
    12241 cagttttgat ttctttgatg aaaaaatttt tgcttcttct cgtccaggag agaagaattt
    12301 gctttctcct aaaaatttga cgacaaatcc tacatctttg cttgtccgaa cagacaaacg
    12361 ttttgcagga gctgtatctg ctgaattaac acgtcaattt ggcagttatg tcgatgttcg
    12421 gacatggggt ggacctactg ccatcttaga gattgtttca aaaggaatcc aaaaagcaaa
    12481 aggcgtgcaa gagattgcta actacctgtc tatcgatcaa aaagacgtca ttgcctttgg
    12541 tgacgagcat aatgatttgg aattgttgga ttatgcaggt tggggagtag ctatggctaa
    12601 cggtactgac caactcaaag gcattgcaaa tgatgtcact cctttgagca atcaggaaga
    12661 cggtttagct gtttatctgg aaaaactact taaactataa tagagaatta gattccacaa
    12721 aaaagaggtt gtgacaattt ttgtcacaac cttttttgcc gagtaaacgg tgttcaaaag
    12781 ccagtttctc ggtatgaagt caaatttaag caaaaatgtg agaagctatt ttcacaaaat
    12841 ttttcttcat actcgaaact aagcggcttt ttcacgacct cttttttatt ttgccatgaa
    12901 catatcataa tacgcgtcca ttatttcttt agcaatcgtc aagtttatgt ggtcttgttc
    12961 gtctaataag ttcggcaaga caacactgat ggcaatttcc ggattgtctg ttggtccgta
    13021 tgccacgata ttactattga ctgtcgcaat atctggatga ccttccgcaa ccgtttctgc
    13081 agtccctgtt tttgcggaaa ggtccatttt cgcactggct aatggtttgg ctgttgtgta
    13141 aggatcggta ccatggacaa cttggtggaa tccttcacgg aggatcgcca tattttctgc
    13201 agaaatattg accgtatttt ctactgttgt gccaatttct ttcttcactt cacccaagtt
    13261 tccattttcg tcattgccat agatcgcttt gactaggtgc ggctgtactc gtttcccgcc
    13321 attagcgact gttgaagcat attgagctaa ttggattggt gtatatgtgt caaactgtcc
    13381 aaatgccaaa tcggtaaagt tacctggagc ataccattct ttgccattat ccgcattgaa
    13441 cttcttcata taatcaacag aacgtgagat cccaggagat tcattcggca aatcgatccc
    13501 agtcgttgta ccaagaccaa actctttgaa agagtctctc aattgctgat aagctttagc
    13561 ttcttcatct aaactaggta gtcccattcc aggtgtatag tctagtccta acatctttaa
    13621 cgccactttg atcatatacg tattagaaga caattccgat gctttgactg catcaagagc
    13681 aacttgtccg cttcgattaa agacagagct tttttctgaa gcaccttgca gacgaatcgg
    13741 ctcatcaatc aaaacttgat ttccgctgat cgcgttactt gcccagcctg ctgtcaaagt
    13801 accagccttg actacagacc ctggatcaaa ggcgctagta atcgtgccta aagcattctc
    13861 ggtgatttct ttggaacctt gttcatgact gaaaccagtc attgctagca cttctcctgt
    13921 ctgaggattc atagccactg cataagcacc aggcgaatac tgtgctttgc cgttgttgat
    13981 caatgtttga taattccttt tcaaaatttc ttctactttt gattggaatt ctgcattcat
    14041 agataacatt aaattagaac ctttttcccc agagaagatt tctttttgat tcgaaacatt
    14101 tccttcatta tcaagggaaa cttcatattg ggttttggtt ccttgcagga catcttcata
    14161 ttgtttttcc aaataacttt gtcctacacg gtcattccga gaataacctt ttgctaggta
    14221 tttctctgct tcatctgctg gaagtccttg cttttcagtc gtcacactgc caagaatact
    14281 tttcagtgaa cttgctgcat tatattctcg tgtccagtct gtgccagtcg aaactcctgg
    14341 aagttcagaa gcgcgttctg ccacaacagc taactcttga tcagtaacac cagagttttt
    14401 gatatagaca gtgtttaatt catatgcact attcatccgt ttaaagatgg tagcaatttt
    14461 taattgctcc tcgtttaaat taatctcatc agctgtgact ttattgacca tcgcactata
    14521 ttgttcgctg ttccctaatt gcttttcttt tgccgaaagt ctttttgtgg cttctttcaa
    14581 atgtttggga tcagccagcc aaaaatcttt tttatctcta tctgtcagat tttcatctac
    14641 cggaacatcg atcagcgagt tcagcttcgt tgcgatttca agcaaatctt tagccgtaac
    14701 ttgtgttcct ctcgtatatg tgatggcctg attcgcttta ttcgtaacta aagcttttcc
    14761 tgtggagtcg tagatcattc cgcgaggagt actttcttgg accgtaatcg tagaagtaga
    14821 cttcactcgc gcctccatct cttcgccgtt cacgatctgc aaataaccca atctagcaat
    14881 caacgcaaca aataacgtaa atataatgaa aaaaagaaaa tttaagcgaa aaggaacatg
    14941 ggaccggcga aacgttttgt tcttaggttc ttgtgcacct tttcttattt tttctaacca
    15001 agaagtattt aatatttttt tcataaaatc tttcatcatt tcctatcctt ccgcctattt
    15061 acattcatgc ttcattgtac ccaaaaactt cttaataaaa aagaaaaaat gggcggagca
    15121 agaaattctt tacctaattt caagataaaa tcaacttttt gtttcacagc aatcacttaa
    15181 agttacatat ccaactattt ttttcattaa aaaataaact tatttttgaa aattatgttt
    15241 tcttaagtcg tgaaacactt tgatggatca tttatttgtg gaaaactacg ttttgttatt
    15301 ctaaaaaact tatataaaaa atagtaaggt ttttatttcg aatccataaa atattcttgg
    15361 attgcttctc gtgttttttt cactttttcg ctaagctttt cgtttttagc catatagaaa
    15421 taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg aattagttgc cgcacttcga
    15481 ttcgtgattt cttttggtct agatgtttgt acgagtacat cggctatctt gctaagcggg
    15541 ttatttccaa attgcgtcaa cgcaatgatt tcgatattca tgcttttcgc cagctcggct
    15601 aatgcgacta catctgcact tctacctgag tttgaaacaa gccaaagcac tttctttttc
    15661 tcattgctga caagttgcgg gagcaagacg tggatatctt tttcaaaaat gattggctta
    15721 ccgacacgag accatttttg cagaatatct tctactacta aagaagaggc gccaacccca
    15781 tataaaaaaa cagtctctgc cgattccaaa cactctacga ctttttggat cgtttcttct
    15841 tctagaatat ctactgtttc ttttatcgct acttgtgcat tgttaccaag tttgtttttg
    15901 atagagtaaa aggactcatt tgcttctata tcactaaaac cttcatcgat tccagtctgt
    15961 agttctgttg aaatcgtgat tttgaagtcc gtcagacttt gaaaaccgat ttttttggaa
    16021 aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg ctaattcatt agctgtcatt
    16081 gtagggacct tctcaatatt accgataatg tagttggcca actttttttc tgctgaagaa
    16141 taatcttcca tcatactttc aatacgacta attacgctca taagttcctc caccctttta
    16201 atgatagtct atgtaagtat accatatcag acccttattc acggtcgtat actggataaa
    16261 aaacaaaaaa acaatccgcc caacagaata tcttatccca tcaatcccac agattctatt
    16321 gagcatctgt gtctttgagg aatacctgtt atctattgtt cggattgctt tctatctact
    16381 acttttttac aggaaattta cctattagtt ttctctgctg taatttttga cttctgcttc
    16441 catagcatca ataaagatat tcaaatcttc tacagctgtt tctttacttc cataacgacg
    16501 tacgttcact gttgcatctt ccaattcctt gtctccaaca actaattggt aagggatctt
    16561 ttgtgtttga gaggcacgta tcttatagcc cattttttca ttacgatcat caacttctac
    16621 acgcaacccc ttcatttgca aacgttcttt gatttcataa gcataatcgc catgtgcatc
    16681 aacagaaaca gggatgattg ttgcttgtat aggtgccaac catgttggaa aagcgccttt
    16741 gtatacttct gttaaataag cgacaaaacg ttccattgta gaaacaattc cgcggtggat
    16801 aactactgga cgatgcgtat tttccccgtc ttctccaaca tatgtcaaat caaagcgctc
    16861 tggcaataag aagtctaatt gtatagttga taatgtttct tctgtaccaa gagctgtttt
    16921 gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg ccttctgctt caaagtaatc
    16981 tagttctaat tcatccatag cggctttcag cattgcttgg gctttttccc acattgcgtc
    17041 atcatcaaaa tatttatctg tattgtttgg atcgcgatag ctcaagcgga aacgataatc
    17101 tgtaatattg aagtcagcat atactgccac catcaattca agcgtacgtt taaattcatc
    17161 tttgatttga tcaggacgaa caaatgtatg accatcattc aacgtcattt ctcgtacacg
    17221 ttgtaaacct gacaaagcac ctgatttttc atagcgatgc atcattccta attcagcgat
    17281 acgaattggt aattcacgat aagaatggat cgtgtttttg tagaccatca tgtgatgagg
    17341 gcagttcatt gggcgaagaa caagcatttc gccatctccc atatccattg gcgggaacat
    17401 gtcttcttga taatgatccc agtgtccaga tgttttgtac aactcaacat ctcccattat
    17461 tggtgtatat acatgttggt aacctagact aacttctttg tctacgatat aacgttcgat
    17521 cgtgcgtcgg attgttgccc cttttggaag ccagaatggc aaaccagaac ctacttctgg
    17581 ggaaaccatg aacaagtcaa gttcttttcc tagtttacga tggtctcttt cttttgcttc
    17641 ttcacggaga cggatatatt ctttcaaagc tttcttgtca aaaaaggctg tcccgtatac
    17701 acgttgcatc atttgattgt ttgagtttcc acgccaataa gcacctgcca ctgataataa
    17761 tttaaatact tgtatacggc cagtggatgg aacatgtggt ccacgacaca aatcgatgaa
    17821 ttcgccttgt tgataagcag taatcacttc ttcttctggc aattcactaa tcagttctac
    17881 tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt tttgaaagaa cacggcgttc
    17941 gatcggcaga ttttctttga cgattttcat catttctgct tcgattgccg gcaaatcttc
    18001 tgcagttact tggttttgtc cattatctgt atcgtagtaa aaccctgaat cgatagctgg
    18061 tccaacgcca aagtggatat ttggatagag gcgacgcatg gcttgggcca tcaaatgagc
    18121 tgctgaatga cggactaagc caagtgcatc ttcatggtct ggtgtgatga tctcaatact
    18181 tgcatcttcc tcgattggac gagtcaaatc aacgagtttt ccgttcactt taccagctaa
    18241 agcttttttt gctaagcttt ttgaaatgct ttcagcaatt gccaatgttg ttgttccaga
    18301 ctcaaattct ttgactgcac catctggaaa agtaattttt atcataatag tttcctcctt
    18361 gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa aaaaatccta gcatctcttg
    18421 aaaagagata ctaggacgaa aagttcgtgg ttccacctaa tgttcaaacg caaatgcgtt
    18481 cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca agggtttcga aagtggtcat
    18541 cctttggttt tctcctggaa aagtttcagc ctagcttttc ctctcttatc gaagactctc
    18601 aaattcagtt ggctttctca tcaatcaatt atgtgtttat ttaaccacta ataaatagaa
    18661 aaatcaagtg ggaaactaaa cttatttttt ccattcccca tttacaccgt atgttccttt
    18721 tttcatctca ttgatgatga catggatgtg ttcttttggt gcctgcgtgt ttttatgaac
    18781 agcttccgtg atatctttca tcatattttc taattgttcc ggactgcgac cttctactaa
    18841 ttcgacatgt acgaatggca taatgctctc tcctctttct gatcgttctt ttttcaactc
    18901 gattctatca tactatgttt gtcttgggta ctgaatcagg aaaaatggct ggatcttttt
    18961 ttgctctcaa ggcactcaaa atagagaccg tatccacgac ttcttgcaaa acagctccga
    19021 ataatgcggg gattagtccc gtacttgcaa ttaacatcaa aaaaatacaa ataaagatgc
    19081 caatcagtac agactgtttc gctattctca tcgtatctct tgaaatcact actgcttttg
    19141 ctacacgcaa gagatcatct ttcaagatga ccgcatctgc actttcacta gcagctgtag
    19201 aaccatgagc ccccattgca ataccgatat ctgcagcagc aagtgctggt gcgtcattca
    19261 cgccgtctcc taccatcgca acaggtcttt gatctttagg gatactttct aaaatggtca
    19321 gtttatcttg aggcaagcta cgggcatgta cagaatctaa ttggactttt tctgcaatcg
    19381 tttgagcaat ggcagatcca tccccggtga tcatcatcaa atttttcaca tcaagttttc
    19441 ttagctcctt gattgtcttt gctgcttctg ggcgaatctg atccgaaaat aggatcgttc
    19501 ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt ggacgtttct atttcttcag
    19561 ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt attgactact gcttggattc
    19621 cttgaccggt cacttctttc agttgactaa caggatacag ttggctgttt ttcacgttgt
    19681 tcactaacga acgagctaag atatggctag attcctgttc tgcactagct gcatacagaa
    19741 gtagctcttc tttttttatt ccattgactg gctgaatcgc ctctacttcc aatatccctt
    19801 tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt acgtgcgagc ttttcaatcg
    19861 ttgttccagt ttttacaacg atcccgtttt tacttgaacg gctcattcct gcaactaaag
    19921 caatgggcgc agctagaatc agtggacaag gtgatgccac taccagtacc tcagcaaatc
    19981 gtaaagggtc ttttgagaac caccaagaaa taccaccgat caaataagca atcaacgtga
    20041 aagggactgc ataacgatca gctaaacgga caaatcgggc aggcttttct tttgattctt
    20101 cgactagttt aataatcatt tgatactggc tgtctgcggc acgtttttca gcgatcattt
    20161 ggatcgatcc gtctccattt aaagaccctg acataatctg atctccaggt ttcttggttt
    20221 ccgggcggga ctcacctgtc aaagaagatt catcgaccga agattctcct ttggtcactc
    20281 gaccatctgc gggtacaagt tcgccaggct tgactagtaa ctggtcatca atatttattt
    20341 catcgattac tatatcctgc aattttcctt ctttgaatcg atgggcaatt cttggggtgt
    20401 tatctaacaa agactgcagt tctttacccg ctcgtttatt cgcgtaatcc tctagactat
    20461 ctccgcccgt aagcatgatc aatatcatca aactagccca gtattctttg acggctaatg
    20521 ttgcaaggat tgcggtaatc gctaatacat ctacgccata tcttcctgaa cgtaacgtct
    20581 tgatcatttc caaaaacatc aagaaggcga gaatccctcc agtaaatgcg acaatcgcaa
    20641 atgcaagggc cggctggtga aaaacaaatt cacttaataa agctatccca ccaataagca
    20701 aagtaagtaa aaattttttg aaatgtgtca ttgttttttc tcctctttta tgtgacttag
    20761 agaggttagt aataaatttc cagctgcctc tttcatctta agcatagtcc ttgactagca
    20821 ctttttaaaa caataggcct taattgaaaa caactatcac tatcagcgtt tccaaaattc
    20881 atcagttcta caaacaaaaa tattcagcaa ggattacttt ttcgattcat cagttaaaaa
    20941 gtaccttttt tcgaaaaact atgctatact tttaattcgt tatttacggc ggaaggagca
    21001 aacatgcgat gaatgagaaa caactagaac aaacgcacgt ggatgaaacg atcgaactaa
    21061 tccagatcga acaaaatatg ctggatacaa aacaacaaga attgactcag gaaatgaatc
    21121 attcgacaaa agacacagct aatcacaaga ttcgagctgg ttccaatgaa gctttttatg
    21181 aatctgctgt tgaatatcgc caacatgagc aggaattgct tttgaaatac catactcttg
    21241 aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa agatagtcct tattttgccc
    21301 gtatcgactt taaagaagac cgtgaaacag aaacattata tctaggtatc gcttctttaa
    21361 gagatctggc agaagaaaca atcgttattg actggcgcgc accaattgcc aatctttatt
    21421 atgaaggtga gattggtccc gcattttatg aaactgaaac agatagaata gatgtcgatc
    21481 tgcagttgaa acgacaattt aaaatccaag aaggacgtat tttatctatg gtagatacgt
    21541 cggaagtaat caatgatgac tttttgctag agatattgga tgaatcatca agcaaccata
    21601 tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc aatcattcgg gacacaacaa
    21661 gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa gacatccgct ttgcttcaac
    21721 gtattgcttt tctgttgtat cataatcgca agtggctcga ggctgaaaac gttcttctat
    21781 tttcacccaa ccatttgttt tctgattaca tctcgactgt attgccttca ttaggtgaaa
    21841 gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca gctgctgcca gagttttctt
    21901 tactagatga acagcaacaa gaaagtggtt ttttgctagg ggaaaaagat ccgatacaag
    21961 tgatgaaaag cggattgacc ttagtcgatc agattgatcg ctatatccaa ggcatcacaa
    22021 actacggtcc cttgttccgt gatatgaaaa taaatggccg tacgatccta tcaaaggaat
    22081 cgattcgcca atggtataaa gaaacaaatg aacaattacc tttacatcat agactttctc
    22141 tattacaaac gaagctcctg aaaaaattag gcggtctgca aaaagacgaa acacgtcagc
    22201 aatgggtcaa agatctggcg gaagaacagc tccaagaact atacgcaaca gatccaaatc
    22261 ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa actggccaac caaatcgtac
    22321 gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta tcaatttgtc aatataacga
    22381 aacaatatct ccactttcta caaactgtgc cactttctct tctaacacga cataaaatca
    22441 gcgagaccag gtggcaggaa catttgacaa ctgttcgtac acacttgcgt caaagagaat
    22501 tgcgtcaaga ggatgctgta ctattctttt tactgatgcg ccgaacatat ccagtgacgg
    22561 ttacacacaa agctcgctat atctttattg atgaaatgca ggatttcgca ccatcacaag
    22621 tggcattgct gcaagccttg ttcccaaaag caaatttgac tttctgtgga gatctaaatc
    22681 aaaatgtctt tggaaatgaa acgatcgttg gatcattgga agaccttttc gtggaccgtg
    22741 aagtcactcg tttccaatta acgacaagct atcgctccac aaaagaaatc actgattttg
    22801 ctaatcattt tattgtgaaa gaacatcaag tagaaacaac agcaagaaaa ggagaccttc
    22861 ctttgctcat ccaaggaaca acagatgata tcaaattgaa ttggttagca gataccattc
    22921 gaacgactca gggaaaagcc cggtattggc gtacagcaat catagctaaa acacaagaag
    22981 aatgcgaagc tctttatgct caactgccag acgagttgaa acaacaagtc cagctgattt
    23041 taaatgagag tgactttatg aagcgttcca ttattttact tccagccttt ttagcaaaag
    23101 gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc agaacatttt tcttctcagc
    23161 aagacaaatt gatcctttac accatgtgta cacgtgcgat gcatgaattg acccttttta
    23221 cctccaataa tgaaagtcct ttgttaaaca atatggatat ttcatcttat gagaaaaaag
    23281 tactgtaagt aaaaagacaa ctgctatcat taatgttagc agttgtcttt ttatttacaa
    23341 taataattgc agaaaaagta attcaatcat ttaaggtcat ttattctata tataaatcca
    23401 aatctgtttc aggatatttt aatttgacaa gcgaaataat cattttcagt tcttccatgt
    23461 tttctggata ttctgggtca aataccttgc tatgacggcc aatcccgcca ttgtcgatca
    23521 atcggtaaat tcgattccat tcaatgaatt ggtcaattga ttggaaattg ctgattggat
    23581 agccgccaca atccaaaatc tctgatacac gaaatgctag gtatgcacta tcgatcactt
    23641 tatttttttt cgtgtctatc ttctcatttc tttcgataag aattttttca ggacgatgtt
    23701 tcaagctcca ctctaatagt agaaagaaag cctccatccg atactcttct tcaaataacc
    23761 gaaaggctga atcagaacga cgaaaaagca gcggaatcag ataattttgt ctataaatca
    23821 gcattggtgc gcggtccacc atacactcta aataacggtt cagataccct gtaccgacat
    23881 agtttcctaa tcgatagcct tcaacgccga atcttgcgta tttttgcgct aattttgaac
    23941 aatcagttac gttcacagct aactcttcta ctttgcggta accgcttaag atacgttcaa
    24001 aaggttctaa agtgattttt gcttccatat tcttccccgt ccatcttcca catacttcat
    24061 atcatttcac atgatactta tgctctcatc ataccacagg ttgaattaga aaagaaaata
    24121 aatcacacaa aaaagcaaga caatctgtta gtgagattgt cttgcttttc gaaaaagact
    24181 gaatactttt cgttaaaact ggttgcttag tcttctaatg ccacattatg gaacacatgc
    24241 tgtacatctt ctagatcttc cagtgcatca atcatttttt caaatgtttc ttgatcttct
    24301 ggagatagtg ttacctcgtt ttgagggatc atttggatct cagcgattga aaaatcagtg
    24361 attccttttt cttttaatgc ttcttgtata ctatggaaat ccgctacttc accgtaaacg
    24421 atgatttgtc cttcttcttc cattacatcg cgaacatcga tgtctttttc cattaggtat
    24481 tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga ttgctgtatt gtcaaacatg
    24541 taagaaaccg ctccggaaac acccatgttc ccgccatttt tcccaaatgc tgcccgtacg
    24601 tctgctgctg ttcgattcac attgttcgtc aatgtatcaa caatcaccat tgagccgctt
    24661 ggtccaaatc cttcatagcg caattcagag tatgtttcat ctcctgcacc ttttgctttt
    24721 tcgattgctc ggtcaataat atgttttggt acattataag ttttagcgcg atcaatgacg
    24781 aaacgtagtt tttggtttgc atgcggatca ggatcacctg attttgctgc cgcgtagatt
    24841 tcaatcccaa attttgcata aatccggcta ttattagcat ctttagcagt tttctttgct
    24901 acgatatttg cccatttacg tcccatattt tcacttcgct ttctgatttg atagtttcat
    24961 aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg attctgtgaa gctttttttc
    25021 tttcttcctt cattcttctc atttttagtc aattatctat actcggattg ggatttgccc
    25081 gaaattctgt tccggaatat tgcctcccaa ttgatagatt tgatcacttc taactaacag
    25141 ttccgcttct tgtgcctctt tttttccgat tcgggaataa atagaaatct cttttttttc
    25201 ttttaagaat cttcttccag catcggtaaa tccaagtagt cgaagataat ttttattttg
    25261 ttggacagga atctcttgct ttttgatatt cagcaagaca taacaagata atcgttggat
    25321 ccgtgtccat gtatatcttt ttgtttttac ctttgacaca aaatcctcaa aactatcagc
    25381 agttgcagct gctgttttca tgcgcgattc tattccttcg gtcatctgat agatatctgt
    25441 cagttccagc aaagtagaag ataacaaccg ataacgcaaa tacggccaat aagattccca
    25501 agtctgcagc gaacaagttg aaagatcttc ttctgtctga ggcggcacaa gtccagctat
    25561 tctttttcct tcttctaacg catggcgaat ggctgttgca ctggctatcc tctgatctgt
    25621 gatgattttt tcatgatagc ctgcactttt acgtcggatc ggatgtaatt ccatagggtg
    25681 gacatacttg gcattttcct ttgcataact taatcccaag atatgatttg gcgaagaaaa
    25741 atcaagcgta atatcgggat acagactgcg aaaaacctca gtcatttttt gcggataact
    25801 atacgtttga tcagacagtt cttgaaatgc ctcttctatc ctatcttgat tctcttggac
    25861 aaagcgtccg aaactgctgt aatcaaacga agtctcttct tctgttccaa aacacaaact
    25921 gtcacagtcc agtgtttgca agatttttac tgcaccttta gcaaaatagt cagctgactg
    25981 aaccgcccat tcgacgggaa gctccactac taaatccaca ccattttgta aagcttcatt
    26041 cgcgcgatgc catttatcga tgatagccgg ttcgcctctt tgcaaaaaat tcccgctcat
    26101 tacagcaatg acgacctctg ctcctgttat ttttcgtgcc atttccacat gatagcgatg
    26161 tccattgtga aaaggattgt actctacgat aatcccgcag cttttcatgc gcatcctcct
    26221 tcatagttat cgataaaaaa gaaatagaga caagtaaaaa aaggcaaaaa tcggaaaaaa
    26281 tacccgaact atataaacta ttctcgcaaa cacaatactt ctgcgacgaa aagctgcact
    26341 gcaagagcaa tgcctatatc gttcggatat ataatttatg ttgaagattt attcttttct
    26401 tgttaactcg agcaggcaaa accgctagtc tttgtatgct acaaagaacc agcgctttga
    26461 tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct tcgactttcg aaaagccgct
    26521 gttttccagc attcttaaat aactttccaa tggataggta cgctcttgat gtagttcatc
    26581 ttcacgaata aatcgaccag acccttcttg ttcttcaacg aaaaaggtaa gaaaatgttc
    26641 gatgctgtgt ttctcgcttc ctggataact atcccacaaa aaagcaaaat tatccccttg
    26701 ataatgatag ctatattctg gaaaaacctc atctacttga taggtggagt gtacgtcaaa
    26761 taaaaatcgg ccattttctt ctaacgcttg atagacttca tcaaacactt gctgtacctc
    26821 ttgtctattt ttcatatagc acagcgaatc agaaaaacag gtaattgcct gatattgtcc
    26881 gatttctgat aaatcgagca tattgccttc cacaaattgg atcgatgcgt cttcttcata
    26941 tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg tctaaccctg tcactttata
    27001 tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg catgccagtt ccaaaatatt
    27061 ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac cattgctgat aaagtgtttc
    27121 gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa gccatatgtt aatccaacca
    27181 ttcactaaga tcgactagcg gagcatctga ccatagtttt tccagattat agaaatttcg
    27241 ttctggcgca tggaaaacat gtacgatcac atctccaaga tcgatcaata cccattttcc
    27301 gccttctttt ccttcaatac gttttacttc atatttgttt tcttcttctt tatcaatgat
    27361 ttcttctgta attgcgttga tttgacgttc gctatttgct gaacagatca tgaaataatc
    27421 tgccaacaag gaaacatttc gaacgtctaa agcgataatg tcttctgccc gttttgaatc
    27481 tgctgcttca atcgcaattt ttaattgttc tttactatct atgatgattt cctcctaata
    27541 tgagcagctt atttttttgc tacccagtaa ttatatgttt cgattgtttt tggataaatc
    27601 tgttgttctt gcgcaagcaa atgggccaat gtatgttttg tttcaaatgc tacagcttcg
    27661 tctagatcag cccatgcaat ggctcgtgca tcttgtaccc caggaaaatc tcgacctggt
    27721 tcaatatagt ctgctacata aatgattttg tcaaggagac tcatcttagc agccccagtc
    27781 gtatgcaccc ggattgcatg aagaatctct gcatcggtga ttcctaattc ccgctctaca
    27841 aacgaagcgc caacaagacc atgccagatt gcattattat aattcaataa ctccggatca
    27901 aaaccgtctc ttacgattac cattttgaac tcctcatctg gtcgttcttt tgcataatca
    27961 tgtgtcaatg cagcaatact agctttttca ggagaagcac cgtatttttt ggcaagagcc
    28021 acggctgttt cttctactcc aagcacatgc ttgaagcgtt gttcgctcat tctcatctgt
    28081 attttttgca tcaggttttc tctagaataa gcagtatatt cattactata gtccatattc
    28141 atacaaccct tcattttgaa tataatcaat tactttatct ggaacaaggt agcggataga
    28201 acagccttct ttgatctttt gacgtatttt cgtggaactg atgtcgatct caggtacatc
    28261 tacccaaatt acaggatatg gagtatccgt tgtgtatcct ggtcgacgta tacccacaaa
    28321 gttgaccata gaagtcagct catcgatttt ataccatttt ggcaaatatt ctaccatatc
    28381 cccaccgata ataaagtaat aatctgtatc cggattgttt tgcgtcaatt ccttcatagt
    28441 atcataggtg taacttttcc caccacgagc taattcaatc gtttcaatct gcaaaaaagg
    28501 attgtcttcc accgctaatt ccaacatgtt gagtcgatgt tttgcatcaa tcgtctgttt
    28561 ctcatcaaca tgaggtggct gataagaagg catcaaaaat acgcggtcaa gacctaaatt
    28621 ccggccagct tgttcagcca tcactaaatg tgcaaggtga acgggattga atgttccgcc
    28681 caagatccct acttgctttt tcttctctaa gaattgaggc atttcttcag gaaataattg
    28741 tgaacgaaca aatgtcttag cttgcgtatt catcatggtc actccttata ttgcttttac
    28801 ttcttttgat agcctttgat acttttcttt tgtggaaggt ttgtataata caataacacg
    28861 tccaatgatt tggacgattt cgcaatctat ttctttttct aatacttgag ctgcttcttc
    28921 tgcaatctca tctgtatttt gaagtaacga tactttgatc agttctcttt tttctaaagc
    28981 ttcttcaatt tgaacgatca ttgctgaatt gatcccacct tttccgattt gaaaaatcgg
    29041 ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt tttcctctta aactcataat
    29101 tttccttctt ccttaaatca atgctttgcg tttcaataca tctacaccct ttggcgccca
    29161 gcccgcaatt actactggcg ctgttacagt gatccagcct agaccggcaa aaacgatgtc
    29221 tgttttttct ttcacagaaa actcaaaacg aacaagctcc ggaaatgcct cgacttcatc
    29281 aggacgagga ggctgtaata atccacctac atgtttttga taaaattcgt ctgctttttc
    29341 cagtttcgtt cgatgaatat ttacatcatt tgacacataa gcaataaatg aagcacgatt
    29401 gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa agtgtttgcc cttcattcag
    29461 ctgataaact ttaggtttga tttcttttaa cggtgcaatg atccgcaaat cttttttacc
    29521 taagtagtgc gccatttgat ggcgatggat aattcccggt gtatcaatca aaaaatgccc
    29581 gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct ggaaactgcg aagttgtgat
    29641 tacatcttgt actcccgctg tatttttgat gatttgattg ataagcgtcg attttccgac
    29701 atttgttact ccgacgatat agacatcccg tccatcgcgg tattcttcga ttttttctaa
    29761 tagttccgtc atctcatgag atttcttagc actagttaat aatacatcta ctggacgaat
    29821 tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat ttagtttttt tcaatgattt
    29881 aggtaatata tccactttgt tcccaactaa aagtactgga ttgtcaccga caaaacggtg
    29941 tagtcctggg attagtgaac cattgaagtc aaaaatatcc accacattga cgatcaatgc
    30001 atctttttgc cctaattcat tcagtaagcg caaaaagtcg tcatccgtca atgagacatc
    30061 ttggatctca ttataatggc gtaatctgaa acaacgctga caatagactt ccccggaagc
    30121 taaacctttt tccaaagccg tttgcggcgt gtatcctaat tcaccgggtt tgtttgtttg
    30181 tataacggca ccacagccga tacattgtaa ttcttctgtc attcgattcc acctcgccag
    30241 cccatatcag ggtgttttgc taatagatag gccataattc ttttttccca aaaacgatta
    30301 aattgtgtct tccaactatc tgttgcgata atgggtttta caaggatgct acgtatccct
    30361 gcacgattgg ctccacgtat atcagtcata atctgatcgc ctaccattac tatctcatca
    30421 tctgctaaat ccaattgttt ctttgctatg ttgatccctc ttgctaaagg tttcattgct
    30481 cgtgcaacat acaaaagatc aaatttttca atcgctcgcg cgacacgttt tgaattattg
    30541 tttgaaacaa caacaacagg gattcctgca tttttcattt ctaaaatcca agtaagcaac
    30601 tcttctgttc catctggatt attccatgca atcaacgtat tgtctaaatc ggtcaatact
    30661 gctttgatgc ctagattctt taattgggca ggtgtaatct gatagatggc ttctaccatc
    30721 catgttggtt tgtaatttga aaacatgctg tctcctcatc tgcaaaaaat gaaggagcac
    30781 ataaagtact cctcaacccc gtattatact gcatatcagc aaaaaaaact acctctatac
    30841 tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac caaaaataaa gattgatcac
    30901 agaaaaattt agaaacaaaa aacaactaat attggcggaa cctcttgtat cgtttttcca
    30961 gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct ttcaatcaac gcttttttca
    31021 taatgtgtgc gactttatat cgtggcaact gctcgccgtt gaacgtttca ggaataactc
    31081 gatcaacgat tcctaactcg cgtagttctg gcgcagtaat tttcatcaac tcagctgctt
    31141 ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa tccttctgga gaaagcacag
    31201 cataaatcgt ttcttccagc atccagactt catccgctaa acctagagca agggcaccgc
    31261 cacttccacc ttcaccaatg atgatggcga tgatcggtac ctttaaatca gacatttcga
    31321 gcagatttct ggcaatagcc tctccttcgc cgcgctcttc tgctcctaca ccgcaatatg
    31381 cacctgctgt attgatcaag gtaatcaccg gtctattgaa cttttccgct tgtttcatca
    31441 gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc aaaatttctg cggatatttt
    31501 cctgcagatc ccgtcctttt tgaataccga tcactgttac cggtttgcca tctaatcgag
    31561 cgattccacc aacaatcgct tcgtcatctg caaataaacg atcaccatgg cattcctcga
    31621 aagaatcgaa gatctcttca aaaaaatcca agcttgtcca tcgttcttta gctcttgcta
    31681 actgaacgac atcatgtgct gtcttatcca cgatctatcc atcctttctg tgtatgcaat
    31741 tcaagaagcg tatggatttt ctgtttcaat tccatgcggg gaacaatctg atcgacaaaa
    31801 ccatgagata ataagaattc agccttttgg aaatcttctg gaagttcctg cttgatcgtc
    31861 tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt ggggttctgc tagaataata
    31921 tcgccttcca ttgcaaaact ggcagttact cctccggtcg tcgggtccgt taaaacagtt
    31981 agataaaaaa gaccttcatt gctatgccgt ttgacagcag cagagatttt tgccatctgc
    32041 attagagaaa agattccttc ttgcatccgt gcgccacctg aagctgtgaa caagacgact
    32101 ggaagacttt cctttgttgc tcgttcgaat aatctggtga tcttttctcc gacaatcgtt
    32161 cccatacttc ccatgataaa attaggatcc atcactccaa taatgaaggg aatcccctga
    32221 atggttgctt taccagtgag gactgcttca tgaagtcctg ttttatcttg cattttttta
    32281 attttttccg tatattcggg aaatgctagc ggatctttgg ttacaagatc cgtatcccat
    32341 tcttcaaaac ttttttcatc aataatcaaa gctagacgct gccatgcacc gattcgaaaa
    32401 gcgtatccgc aatgagggca tactttttct tcaccgatgt ctttcgtata aaggatatgt
    32461 ttgcaatttg gacactttgc ccacatgtta tcaggaacag atggcgagtt agcaggtttg
    32521 ctctctctat taggattgat ccgaatatat ttctttttct taaacagagc catctatgcg
    32581 cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt cttcttgtaa aaatgctgtg
    32641 ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat ccatctgaaa ttctgcgttc
    32701 gtgatgattc cttctgtgat aaattcactt aaggctcgct gcatcttcat taatgcttca
    32761 aaacgcgtat ttccatggac gattattttt gcaatcattg aatcataata tggcgggatc
    32821 gtatatcccg ggtaaactgc actgtctact cgcagtccca tcccacctgc tggaagcagt
    32881 aagttttgga tcttccctgg agaaggagca aaatggaaag caggattttc tgcattaatc
    32941 cggcattcga ttgcgtgtcc ttggaatact acttcttctt gacacacatt caaaggctca
    33001 ccggctgcta tctccacctg tttttttact aaatcgattc ctgtgaccat ttctgttact
    33061 ggatgttcca cttggattcg agtattcatt tccatgaaat aaaaatcgcc ttcttcatcc
    33121 atcagaaact cgatcgttcc ggcattttca taattgactg ctttagctgc tcgaacagca
    33181 gcgtctccta gtgcttctct ttttgtttgt gagatcacta cagaaggaga ttcttccagt
    33241 actttttgat tgttgcgttg taaagaacaa tctcgctcgc ctaaatgaat gacatgacca
    33301 aatcgatcac ctaagatctg aacttctata tggcgagcag gataaatgat tttttccaaa
    33361 tacatatcat catttccaaa tgccgctgct gcttcttgct gagctgaaga aaaatgctgt
    33421 gggagctctt cttttgattg aactttccga atgcctttcc cgccaccacc tgcagctgct
    33481 ttcagcatca ctggataacc aattctgtct gctatttcca atgcttcttc tactgtagat
    33541 aatacaccag tacttcctgg aatgactggg acatttgctt cttgcatcaa ttgacgcgca
    33601 ttgatcttat ttcccattgc atcgatcgtt gcacttttag gaccaataaa tgtgatattg
    33661 cactcttcac acatggaggc aaatcggcta ttttcagata aaaaaccaaa tcctggatga
    33721 attgcttcgg cttttgtcac gattgcagcg ctcagtactt cctgaacatt cagatatgaa
    33781 tcaacggctt ttgccgggcc aatgcagatt gcttcatctg ctaactgtgt atgaagtgct
    33841 tcggcatctg cttctgaata tatcgctacg gtttggatcc ctagttcgcg gcatgcacga
    33901 atgatacgta cagcgatttc accgcggtta gctatcaata ctttagaaaa catatttcac
    33961 ctatccaatc ataaaggtta attccgcttc ggctactttt ttaccgtcta ctttagcgat
    34021 tcctttgcct attccggctg aagctttcac tttcaatatc tcaacttcaa ggtataaggt
    34081 atctcccggt gtaactttct tacggaattt tgctttgtcc aatccgccga aataagccgt
    34141 ctttcccttg aattgttcaa gagaaagtaa tgcaactgct cctgcttgag ccattgcttc
    34201 aacaatcaat acccctggca taacaggttc ttctggaaaa tgtccttgaa aaaagggctc
    34261 attgatcgtt acatttttct tagcaacgat ccgttctcct tcaaccattt cttccactcg
    34321 atcaatcaaa agcattggat aacgatgtgg aatgatttct tttatttctt gtatgttcat
    34381 tgttttccct ctttcctgct ttgcttattt ttgctgaatc ctaaagagtg gctgtccata
    34441 ttcgacaact gactcgtttt ctacaaggat ttctgtgatc actccgtcgg cctcactagt
    34501 tatctcattc atcagtttca tcgcttcaat aatgcagata acttctcctt tggcaacttg
    34561 atcacctact tttttgaaag ctggtttgtc gggcgctggt tgcagataaa cgattcccac
    34621 gattggcgaa acaacctcga ttccatcaaa tactgccgat tctttttctt tcattatttc
    34681 tggagcagtt gttgcttgtt cagatatgac attgactggc tccgaaactg gcaacgtttc
    34741 gtttgtttga accatattca tgcctcgact tgttttattt ttattcatat acaattcaaa
    34801 ttgaccttca cgcaaatcga attccgttag cgaggattga tcaaattgac tgactaattc
    34861 tctgatttca ttgatatcca aaattattcc tcccagcgtt tcatgcacag aaccgcatta
    34921 tgtccgccaa accctaatga attactcatt gcataagtaa aacttgcagg tttgctttcg
    34981 tttttgacaa ctgtcaagtc aatctcagga tcttgttttt ctacattgat cgtaggtggg
    35041 ataaattgat gttctaatgc cagcaaagtt gccaaggctt cgatcccgcc ggctgctccc
    35101 aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag tatctctgaa attttcacct
    35161 aatgcgattt ggattgcttt tgcttctgcc tggtcattgg ctggtgtact tgttccgtga
    35221 gcattgatat atccgacttg ttccggctgt acaccagctt cttccatcgc aagcttcatt
    35281 gctttagatg caccagaacc atctggagta ggagctgtca tatggtaagc gtcacagttt
    35341 gcaccgtatc caacgatttc tccatagatt ttggcaccgc gagcttgtgc atgttctaaa
    35401 gattcaagaa ctagaacgcc tgctccttca cccatcacaa aaccattccg attttcgtca
    35461 aacggaatcg aaccacgatt aggatcagtt gattctgaga gtgctgttaa agctgcaaat
    35521 ccagcaatcc ccatctcaca aatcgttgct tctgttcctc cagcaagaat gacatcagaa
    35581 tagccatgtt tgatgttacg gaatgcttcc ccaattgaat tcgttccgct agcacaagct
    35641 gttacgatag ctgtacaaat accttttgca cctacacgca aagcaatatt tccagctgcc
    35701 atgttggcaa tcgccattgg tacgaacatt ggagaaactc gttttgcacc tttttcatgt
    35761 agacgaataa cttggttttc gattgttgga agaccaccga tcccagatcc gatgatgacg
    35821 ccaaaccggt cttgattcat tttttcttta tctaaaccgc tcatctccat tgcttctaaa
    35881 gcagcgtaga ttccatagat cgaaaacata tccattcgtt tgctatcttt tttaataaaa
    35941 tatttatcgt aagggaaatc tttgacttca cccgctaagg taatccctgt ttctgaagca
    36001 tcaaatttag tgatcggtgc gatgccattc gtcccctctt ttaagctatt caaaaagctg
    36061 tctgcgtcat ttccaatagg tgaagtgact ccatagccag taattaccac tcgattcatt
    36121 tgtttgctct ccttttctta tccgtgcatg accaatccgc catcgacatt gatgacttgt
    36181 ccggtgatat atggattttg tgctaagaaa actgctgttt gtgcaatatc ttctacttgt
    36241 ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct tgactttgtc tgctaaaact
    36301 tccgtcatat cagttgtgat gaatcctggc gcaatggcat tacatgtaat gcctctagtt
    36361 gcagcttctc gtgccacaga ttttgttaat cctactacgc cagctttact agctgcataa
    36421 tttgcttgac caatatttcc aatcaaccca gatacactag agagattaat gatggcccct
    36481 tctcgctgct tcatcatttt tttcaatacg tgctgcgtca tattgaaggt tccaatcaaa
    36541 ttgatatcca gacatttttt gaaatcttct gcatccattc gcatcacaag tttgtcattt
    36601 gtgattccgg cattgtttac taacacatgg atcgatccaa gcttttcttc tgcttctttg
    36661 atcatttgtc ccgctttctc ataatcagag atgtcaccgg aaactcctac gcattttaca
    36721 ccgaatgctt cgatttcttc tatcttttct tttggaatct ctccgcgacc attcaaaatg
    36781 atatttgctc cagcttttgc aaaagctaag gccatcgctt tgccgattcc tcttgtacta
    36841 cctgtgataa atacattttt tccttttaca tccataacgt tcctccttat agtattgcta
    36901 ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac tggtattgtt ttatcgattt
    36961 ttttcataaa tccgcttaat acttttccgg ggccgacttc gatgacttgt tcgatgccga
    37021 ttgtttttaa cttatggata ctctcataga aacgaacagg ttgcatgact tgctgttcaa
    37081 gtagtcccgc gattgtttct ttcttcatta tttccgttgt tgtgttgctt atgataggaa
    37141 aagaaggttc agagaattga atctgactta ggtccttcgc cagttttttt gctgccggtt
    37201 ctaaaatagc tgtatgaaaa ggcccgctga catttagagg gatcattctt ttgaaccctt
    37261 tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc ttcgccacca atcacgatct
    37321 gctgaggtgt attataattt gcaggagata cgatgccgta cttgctagct tcatgacagc
    37381 tttcctcgat cgtttcaatc ggcgcattca tcactgcaac cattttcccg cttccagctg
    37441 gggtagcttc tgtcatataa gcgcctcttt ttgctactaa cgcaactgct tcagtgaagg
    37501 atagcgcatt actagctact aatgccgaat attctcctaa actcagtcct aaagctgcat
    37561 ctgggatgat tccatgctcc ttcaataagc gataatacgc gatgctgact gttagaatag
    37621 ctggctgtgt atattgcgtc tgatccaaac gttcattttc tgtaaagcaa agttcagcca
    37681 tatcgtagcc gagaatctca cttgcttcat caaatgtctg ctttacaacg gcttcttcat
    37741 ataaatcttt tcccatacct tgatattgtg caccttggcc actaaataag aatgctgttt
    37801 tcatgttttt ctccaatata tccagaatat atgtttgatt cttcctattc aaaaaggccg
    37861 agacattcct atttcaggaa atgtcccagc ccccaaccta attttaatga ttatgcagtt
    37921 tgtttttcta cgtaagtcac taaatcttga accgttttga ttccgtcttc tgtttcgatt
    37981 ttcacgtcaa attcatcttc aatttcattg atgatttgga ataaatccaa gctgtcagct
    38041 tctaagtctt cttggatgtc agtagtcaat ttgatttctt cagtttcttt tcctaattct
    38101 tctgcgatga tttcttgaat tttttcgaat accataataa tatattcctc cgatattgtt
    38161 tgctttttat ttttataatt taacagtcta caactccatg agaatacttc cccatgttaa
    38221 acctccgcca tagcctgtaa atattacttt ctgctgtttt cctaaggtga tctttccact
    38281 agaaactgct tcatccaata agatagggat gcttgcagca gatgtattcc catatttatc
    38341 catattggtc aggaactttt cttgcggcat ctttactttt cgggcaattt tctcaataat
    38401 tctgaggttt gcctgatgca aaagcagata atcaactggt ttgtctttca tgacttcttg
    38461 gatattgttt gcaacgtctc gtacggcaaa atcaaaaata tctctgccag tcatttgcaa
    38521 ataatacgaa ccttctgaat cttctgaata gaacggattt ttattttgct ggtagccagc
    38581 ggtcaatgag ctacttctgg taccgtcagc tgctaatttt tctttcagca attttttctg
    38641 tggattcgct tctaagagaa tcccacctgc tccatcgcca aacaacacag cagtcgtacg
    38701 atcagaccaa tcgattagct tagatagtgt ttcaccacca atcaccagtc ccttagttga
    38761 gccgcagcgg atcatttttt cagccatgct taacgcataa acaaatcctg agcacgcagc
    38821 actgatatca aaagcgatag catgagttgc tcccaatttc ccttgtactt gtgctgctac
    38881 agatggtgtc gtgtaatcgg gcgacattgt tgctactaaa ataaaatcca aatctttagg
    38941 gtttagattt ttctgtttta tcaatttttc cgccactaaa atgcataaat cagaagtctc
    39001 ctgatttgtt acacatcttc gttcacgaat acccgtcctt gacgaaatcc attcatcaga
    39061 ggtatccatc atcttggaaa gatcattatt agtaataatc ttttcaggaa ggacgctggc
    39121 tgttgcagta atcattccaa attgttccat taaatatcct cacttatagt cttgcaagaa
    39181 gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt tcctccgtag ccattccgtc
    39241 taagatgttc ttgaccattt cacgatgaaa atgctgatgg acccgaaata gtaactttcc
    39301 ttttttcgtt agtcccaact ttacaacgcg gcggtcatct tcactgcgga tacgttcgac
    39361 atagcctttt tttactaact tgttaatagc agtggtcaag gtcccaacag taattgatag
    39421 ttctttggct acttctgaag ttgttttttt cttgtacatc ccgattgcct cgatcgtgtg
    39481 catctctgtg attgacagat ctttgaattg agattttttc agctcagact cttcgattgt
    39541 caaaatatca ttgaagacac taacaagata atcatttact gtttttaaat ctggttccat
    39601 gttccaccgt ccactaatta gtttgattat caaatctttt gatgttcaaa ctatatctta
    39661 acttttttca aaatgcaacc ttaaaagatc atttttttac tatatgagct ttttttaaga
    39721 ttttactcat ttaaaacaac tgataaatca gcatttataa tttcttttat tagaaaaatc
    39781 atctatctca catattttga ttatcaaagt attttctgtg aacagaacta tagaattccc
    39841 taaaacttgt ccattatttc aaaatttgtt atagtctttt tattcaaagc gtaaaaggag
    39901 atcctatgtt aaaagaaaaa atgaaaactc tccccatgct gccgggtgtc tatcttatga
    39961 aagaccgaga tggtaaggtc atctatgttg gtaaagcaaa acggctcaaa aatagagtaa
    40021 gcagctattt tcatcagaat aaacagcatt caaaaaaagt attacgtatg attcatcata
    40081 taacagattt tgatttcgtc gtagtagaca cggaattaga tgctttattg ctcgagtgtc
    40141 aattgatcca acattaccgt cctttttata accgacaaat gaattatttc agtaattata
    40201 attatgtaca tattaccaat aagggatttg tattaacaga tactcctacg gctcgaacat
    40261 acgggccttt tcgtctctat aaaaaaatgc cgtctatttt gcgtataatg gaagaaactt
    40321 atcaaatgcc ttggttgtct gaaattagtt tgttagcttt gcgagtccag cttcctgacc
    40381 tacaggaaat gacttttgaa cagaaaaaaa aggaactcca agggctgttt caaggccgaa
    40441 ataaaaagct actgacttac ttgaaaaaaa gacaacaaca tttcatctat cagttgaatt
    40501 tcgaaaaagc cggtatgctt caaaaagata tcgaattagt tacttatttt attagacgga
    40561 tccaggaaca aaagcagttt ttaagaacac catcgctcac cttcagcatg ccattagcag
    40621 cagatgagag tcagaaaaag cactacctcg tttgttatgg tcaacttgca gaaacaatga
    40681 ttacctctgg tgacgtttct cctgacttct attatgaaaa gaaagaagct catttatctt
    40741 tgaaacgtca attgtcaaaa gaagaaatcg atcctgtaca aatcttgatc agttaccgca
    40801 aaaaattaga aaaagaacag tttgaaattg aactgttaaa caaaaaagaa gctgaaaagc
    40861 aactaaatta gttgcttctc ggcttctttt aggcatcttc aacttcaaat gtcaattatc
    40921 ctaaaattta ttggattaag tcatagattt ccatcgctac gatatcgata ttatcaaatt
    40981 cgtattgctg atgagtatct gtttcagtta attcaaatgt atcggtcgct ttatcataag
    41041 ttactgtaca cttctctacg ccttcttttt caaaacggcg aacttgcagt tcattatctg
    41101 ctgactcgac catagcctcc agtcgtttta tgattgcgac taattgtgaa tgtgtcatcg
    41161 gaggtcctcc ttttcttatt tctgttatat tgtatcaaaa gcatagccta cttgcattga
    41221 ttttctctaa aaaaactcgt tttttatgat tttttttctg gtatttttcc ttcaggccac
    41281 caaagtttga tcaaagcttg ggttccgtca ttctcaaaac ctttatctgc caactcttca
    41341 tatagtttca atgcttgggt agttgctggc aatacaagat ccattttttc tgcttcttct
    41401 aatgcaatct ttaaatcttt gataaaatgt ttgacaaaaa aaccaggtgt gtaatcttct
    41461 tttaaaatac gaggagaata attgcttaaa gaccagttag ctgcacttcc acctgaaagc
    41521 gtctcaatca ctttctttaa atcaagtccg tttttttgtg catagacaag catttccgtc
    41581 attcctgtca tcgtacctgc aatcatgatc tgattagcca tttttgtatg ctgacctttc
    41641 ccagcagaac catgcaatgt aaatgtcgta ccaaattctt tgaataaagg cagtacttga
    41701 tcataaacgg cttcttctcc accgaccatg atcgtcagtg taccattctt tgctcctaag
    41761 tcaccaccgg ataccggtgc atctaacgca tctgcgcctt tttcttttgc tgtttttgca
    41821 attttttctg ccaggcttgg tgtacttgta gtcaaatcaa ctaaaatatg tcctgagata
    41881 tctgcagaaa aaatccccga ctgtccatag tagatttctt ctacatcttt ggggtaacct
    41941 accattgtaa agagaatatt actttgttct gctaccgctt ttggtgtatc tgcccagata
    42001 gctccttctg ttactaaagg atcagctttt gcttttgtcc gattatagac agctacttcg
    42061 tgtcctgctt ctagtagatg gcgtgcgaca gcacttccca tgacgcctgt tccgataaaa
    42121 ccaagtttca ttttttcgac ctcctaaaaa tcaaaaatcc ttgcttctat gctagtatac
    42181 gctagaaaca aggatttttt cataaaaaat gtttgaattt tatcttttaa atgaatttaa
    42241 ttttattttg attcgttcaa tcgagtcttc ttcttctttt cttcgcatct cttcttcatg
    42301 ataaacaacc atgtcttgat aaaattcgat catagcttcg ccgaaatgtg tagatgaaat
    42361 atcataaagt ttagcttcta aaacttttgg atctttagga acttcactgg aaatataatc
    42421 aataagtgct ggtgcaaagt cttcgtcggt ttcaaaagtt ttccctaatg aaggatgatc
    42481 gaacaatcgg ttcaaataag catttccttc cacgacacaa ggtgttccgg ctgccatcgc
    42541 ttctgtataa gtaagccctt gtgtttctga agtagaagca ctgacaaaat aatctgccgc
    42601 tttataataa agtgctacat cattgttgtc cacttctcct gtgaactgca caaattcttc
    42661 taactgcagt tctgagatca attcctctaa ctcttctaca taaggtcctt ttcctacgat
    42721 aactaatctg gcgttaggat aagcggagat gacctgagga aacccattaa tcaaggcttg
    42781 gatatttttc tcataagaaa tcctgcttaa agaaagaatc atcaaatggt tttcctgaag
    42841 acctagtgac tcccttaatt tgctgatatc ctgctgagtg atatcagaac gtttgaattt
    42901 ttcaatgtcg ataccagtag gaatcacgcg aagcggtgct attacaccat agctgcgtaa
    42961 tgtatcaata acacgttcac ttggacaaac tacacctgtc gtatgatttg caaataatct
    43021 agacaagtat tttacatggg attgcctgat cacttttcct ttaccgatat aatgaaggta
    43081 gtcttcatac atcgtatggt aagtatggat cagaggtatt ttcaacttct tagctaccat
    43141 cttcccaagt atccctgctc cgaattctgt atgggtatga ataagatcta gttctagttc
    43201 tttggcaacc aaataagcat accacatgcc tctaacaaca actcttcgat ccttgaaaga
    43261 aataaatggt acacttggca ttcgaatcac atctttttcc aacttatccg cattaggatc
    43321 ggtcgttgta aaaatataga cttcatgccc atgtctttct aattcttgtt ttaatgtttt
    43381 gatcgatgta gcaactccgc tgacttgcgg aaagtaggta tcggtaaaaa agccgatttt
    43441 catgtttttc gcctccaaac tagtccttga cctgatttac tttttttaat ttgctagaga
    43501 ctttttcatt cagtacactt tcgtatacat ttttaagttc ttcaccgatt ttattgatac
    43561 ttcgctcttt tgctgtttga taaccggctt gtgtcgtact cggtagttct tgattggtaa
    43621 tctgttggat cagtcggata aattcttcgt ttgtcttccc catatagcag ttcttgctat
    43681 cttctaacca gccattatac actggaatat ctcgaacaag tacgttttgt ttgcttgcta
    43741 aagcttctaa aacaacgatc ccttctgtct cttcataaga agggaaaaag aatagatctg
    43801 cacctgaata cgcaccttct atgatctctc cacgaatgta accaggaaac aggacatttt
    43861 caggatgatc ttcttttaca attttccgga tgttccgagg aatcgagtac atgggaacat
    43921 gaccaaacca aataaatgtg tattcgggca tcttcttagc aatttctacg aaatcaatga
    43981 ttcctttacg ttcgaaaaac aaaccgacac aaatgattac tttttgatcc ggagacagtt
    44041 tgaaatattc tctgaacttt tgttctttca ttggatcagg gtgatatttc tctaagtcga
    44101 tcccattgga aatagcttga atcggcacac ggataccata gctttccaac aactgttttg
    44161 aataaggtgt tggcgtgatc agatagtccg ctttttggta caatcctacc agatattttt
    44221 ttacgatagg agaaagctgg ttcgatccga taaaggaatt tcggaaatct tcctctgtag
    44281 aatgcgcatg atagacaact ttttttcctt ctcttctggc tttattgacc atattatgac
    44341 tattgattcc gtatgtattg atgtgcagga tgtcataatc ttctttttca tctagtgtat
    44401 aagagatacc gacttccgtc agagcacgtt tttgatgatc aagcgcacgc ccgattccag
    44461 attttgcaag catcttttca ctttcaaaat ataataatac cttcacctta cgtccccctt
    44521 cacttatata gtataacata gcctacaaac tgtcactcaa acttaagccc tatttttgtc
    44581 tattcttact gacaaaaacg ttttcttaaa aaagaacaaa aaaactggcg tagctctttt
    44641 acaagccaca ccagcttttg atacgttgtt tattttacat attcatgaac aagttcaacg
    44701 acttcttcca tcatatcgca ttctttcaat gcacgatcag caagttcagc cattttcgct
    44761 gtgtccaagc gtttcattaa actacgcgtt ttaagaatag atgtcgcact cattgagaac
    44821 tcatctagac ccatacctac tagcaatgga acagctgttt gatctccagc catttctcca
    44881 cacatacctg cccattttcc ttcagcgtgt gctgcatcaa ttacattttt gatcaaacgt
    44941 aaaattgatg ggttatatgg ttggtacaag taagaaacgc gttcgttcat acggtctgct
    45001 gccattgtgt attgaatcaa atcgttcgta cctacagaga agaaatctac ttcttttgca
    45061 aacttgtctg ctaagactgc tgctgctgga atctcgatca tgatgccgac ttggatcgta
    45121 tcagatactt ccttgccttc acttatcaat ttttgttttt cttcttcaaa gatcgctttt
    45181 gctgcgcgga attctttgag tgtagctacc atagggaaca tgatacgtaa attaccatga
    45241 acagatgcac gaagcaatgc acgcatttgt gtacggaaca tttcgtcgcc ttgttcagat
    45301 aaactgatac gcaatgcacg atatcctaag aatggattca tttcatgagg taattgcaga
    45361 tatggtagtt ctttatctcc accgatgtcc attgtacgaa caactacagg ttttccttcc
    45421 ataccttcta atacagcttt gtaagcttca tattggtcat cttctgttgg gaagtctgga
    45481 gaatccatat acaggaattc agtacggtac agaccaactg cttctccacc attattatgg
    45541 acaccaacta gatcttttgg tgttccgatg tttgcagcta attcaaaatg cttgccgtca
    45601 gctgtgacag tttctgcatt ttttaatttt tcccattctg ctttttgtgc tgcgtaatct
    45661 gcacctgctt tttcaaattc agctttttgt tcatctgtag gatcgatgat tacatcgcct
    45721 tcgatcccgt tgacagccaa aatatcgcct tctttgactt tagcagtaat ttcttttgtc
    45781 ccaacgattg ctggaatttc taaagaacgt gccatgatag cagaatgtga agtacgtcca
    45841 ccaatgtctg ttacaaacgc ttttacaaaa ttgcgatcta attgtgctgt atcacttgga
    45901 gtcaagtcat gtgcaacaac gaccacttct tcgttgatca ttgatggatt tggtaaagta
    45961 acgcctaata agtgcgctaa aatacgttta gcaacgtcac gaatatctgc agcacgctct
    46021 tgcatataag cattatcttc cattgcttcg aacataccga tatacatatc cgttacttct
    46081 tttagcgctg attcagcatt tacgctgttg tctttaatat tttgcttgat ttgacctacc
    46141 atttctggat ctgaaagaac catcaaatgg gcatcaaata cttgcgcttc tgcttcacct
    46201 aagctttgcg ctgctttttc acgaatttgc tgcaattctt cagtagattt agctaatgca
    46261 gcatccaaac gagcttcttc agccgcagta tcttctactg ttgccttact gaatgttaaa
    46321 tccggttgaa ctagcaggta agcttttgca acggctacac cgtcactagc ggcaatccct
    46381 tttagcattt caaccattat tcagataagc cttctttctt cattgtttca acgattgctg
    46441 ccattgcatc agcttcgtca gcaccttctg cagtaatagt aacatcagaa ccttgaccta
    46501 cacctaaaga cataacgccc atgattgatt tcaagtttac tgatttacct ttatactcta
    46561 agtttacatc agagttaaat ttgcttgctg tttgtactaa tagtgtagct ggacgagcgt
    46621 ggatcccagt ttctgctact acgtgaaatt ctttcttttc catattaatc ggtctccttt
    46681 aagtgagtgt tgtttttatg tgagggtttt cttttttagt aattcagaga atcctaacaa
    46741 atgccaccct ttcatctgta aagattaaca ttttttttcg ttagatacaa cagttttcat
    46801 tcaatttcag ataaaagtat tcaaattatt ccggattctt tttcatcctt ttcttcacat
    46861 tttataacaa acgtgtttat ttcctttttc ttgtcgcttt ctcttctcct gacgtttatc
    46921 attctttcct ttgaccctct ttgttttcat atgaaacgaa ttacttgctt ccctttttat
    46981 ttttagtata ataagagtca aaggtcagga atggtcaata gagatttcac cttttctacc
    47041 tcataaatct cttaaaaaac taggggttat tcttttacct catgaaaaac gagatgtaaa
    47101 atatggatgt acccattttt gtgaaaggac gtgaatgatt catgctttgt caaaactgcg
    47161 gcaagaatga ggcaacgatt cacttgtatg ccactgtcaa tggtcagcgg acacaactcg
    47221 attactgtca gagctgttat caaaaaatca aaaatcaaca aaatggaggt ctgactaata
    47281 tggcccaaaa tgatccattt ggatttggca gtttggacga tcttttccgt tccatgtctc
    47341 gccaaatgca acagcaagga aattatgagc aaacaccacc aacacaattt ggcggaaaca
    47401 acaacttcaa tggtggtcag ccacctcaag gcaatacaga aggtttattg ggagaatacg
    47461 gaatcaatat cacagaacaa gcacgacaag gtgatatcga tcctgtgatc ggacgcgatg
    47521 acgaaatcaa acgagtcatt gaaattttaa atcgccgaac caagaacaat cctgtcttga
    47581 ttggagaacc aggtgttggt aaaacagcag ttgttgaagg tttagcacaa aaaatcgtag
    47641 atggtgatgt accgcaaaaa ttaatggaca aagaagtcat tcgtttagat gtcgtatctt
    47701 tagtccaagg tactggtata cgaggacaat ttgaagaacg tatgcaaaaa ttgattgaag
    47761 agatccgtca agcagaaaat gtgatcctat tcatagatga agttcacgaa atcgtcggtg
    47821 ctggttctgc tggtgatgga aatatggatg ctggtaatat tttaaaacca gctttagctc
    47881 gaggagaatt gcaaatggtt ggtgctacta ccttaaatga gtaccgcatc atcgaaaaag
    47941 acgctgcttt agaacgtcgt atgcaacctg tacgggtaga tgaaccaact gtcgaagaaa
    48001 cgatcagtat tttgaaaggt ttgcaaaaac gttatgaaga ctatcatcat gtaaaatata
    48061 ctgatgaggc catcgaagca gccgcaactt tatccaatcg ttacgtccaa gatcgcttct
    48121 tgccggataa agccatcgat ttgctagatg aaacaggttc taagaaaaac ttgacgatcc
    48181 aaatcgttga tcctaaaaca atcgagaaaa aactgcaaga agcagaagaa caaaaagttt
    48241 tagcttctcg agaagaagat ttcgaaaaag cagcttatta tcgcgatcag atcaataaac
    48301 ttcaaaaaat gaaagaacgt cagctcactg aagaggaaac acctgtgatt accgaaaaag
    48361 atatggaaaa aatcgttgaa caacggacag gtattccagt gggtgaatta aaagaaaaag
    48421 aacagacaca actgaaaaac ttagcagatg acttgaaagc tcatgtcatc ggacaagata
    48481 acgctgtaga tcgagtagcg aaagcgattc gccgaaaccg tgttggatta aacaaacaga
    48541 atcgtccaat cggctccttc ttatttgttg gaccaactgg tgtaggtaaa acagagcttg
    48601 cgaaacaact tgcctacgaa ctattcggtt cacaagattc aatgattcgt ttcgatatgt
    48661 ctgaatatat ggaaaaacat agtgtctcta aattgattgg ttctcctcca ggttatgtcg
    48721 gatacgaaga agctggtcaa ttaacagaaa aagtacggag aaatccttac agtcttgtct
    48781 tgttagatga agtagaaaaa gctcatccag atgttttgca tatgttcttg caaatcttag
    48841 atgatggtcg attgacagat gcacaaggaa gaacggtcag ctttaaagat acgatcatca
    48901 ttatgacaag taatgccgga actggtaaag tagaagcaaa cgttggtttt ggtgcggcac
    48961 gcgaaggtgt tactcgttct gtattgaacc aattaaacaa ctactttaca ccagaatttc
    49021 tgaaccgttt tgacgggatc atcgaattca gtgcattatc aaaagaaaac ttgatgacaa
    49081 tcgtcacact aatgctagac gatgtcaacc aaatgctggc agcacagcaa cttcacatcg
    49141 aagttcctac gaatgtcaaa gaaaaattag ttgacttagg ctatgatcca tctatgggtg
    49201 ctcgtcctct tcgacgcacg atccaagaac aaatcgaaga tggtatcgct gaattttatc
    49261 ttgatcaccc ttctatccat gagttgaaag caaaactgga taaagatgga aaaatcatcg
    49321 ttacttctaa accagaacgt ttggctaaag aatcagccga agaaacggct gaataaatcc
    49381 agttttatag cgtgagacgg tatttctttg agaaatgccg tctcattctt ttttcagaaa
    49441 agtcaaaata ctgttcattt tataaaaaag aaattataat aagagaaaca agcaattaaa
    49501 aatacataaa agaggtgagc gccatgaaat tggtaaatgt aacaaacagc cattcccgtc
    49561 ttgtattaaa ccagcttgaa aacactgatg cccatctagt caaggtctac acagccggaa
    49621 ataccactat tgtctacact gaagcccctg aacataatga aattctgctg atcaatgaca
    49681 aacgtaaaat ccagccgaaa gaaatcgaag atgctaaaaa ttatttctta gataaaatca
    49741 aagacgccgt ttaccacgag gatgaaatca aagtaatcga attggcaggc cttgttgaaa
    49801 tctcgattcc aaaacatgaa ttaggcgcta cattagccgt gtaaacaaat tttgaacata
    49861 ataattaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta
    49921 taaacggcga aagcagaagc aactccttcg gaaataagct gaaattcacg aaaattgctt
    49981 ttcaaatttt tgtgaattcc agcttatttc ttggagttaa acgcttctgt ctcagcctct
    50041 ttttctttct agctttttga tttttctctt ttcttttgta cttttctctt ttcattttca
    50101 gttctacgcg tgtctttatt tttaactttt tcctctttat ggatgattga tcgtactttt
    50161 tgtgcaattt gctcgttttt gtcccagtct tttacatcta ataatcgaca taatcgtaac
    50221 atctcttctt ttttctgttt ttttctttca cgtctttgcc attctgtttc catgtgtcac
    50281 actctccttt ctttaatcat atgtacgcaa aataattttt atattttttt gattagac
//
LOCUS       DAKCAA010000013        46567 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000013 DAKCAA010000000
VERSION     DAKCAA010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 46567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.013"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(6..2171)
                     /gene="copB"
                     /locus_tag="OUE31_000875"
     CDS             complement(6..2171)
                     /gene="copB"
                     /locus_tag="OUE31_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HCU0221905.1"
                     /translation="MNGNDMEKKQEHKKEAGNKESAHSNEKQMKHDHSQMDHSMHMEH
                     NHGDIADSKQMDHSMHMDHDHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGMEF
                     PFQITFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYIYS
                     VYSFIANLINPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPESV
                     KRLTKEGKEETVSLKEVKEGDHLIVRSGDKMPTDGVILKGETIVDESAVTGESKGIKK
                     RANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAKWL
                     FYVALTVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAAKN
                     GLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGALEA
                     NANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKSQQVKIVNEKEVERLGLN
                     VEQALLKPYQEQGNTISFLILENHLAAIVALGDVIKTEAKEFIRTLKERKITPVMLTG
                     DNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLARAS
                     IGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILAIP
                     LAAGILAPIGILLSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(2191..4377)
                     /locus_tag="OUE31_000876"
     CDS             complement(2191..4377)
                     /locus_tag="OUE31_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HCU0221906.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQSYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQENALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRMTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(4377..4586)
                     /gene="copZ"
                     /locus_tag="OUE31_000877"
     CDS             complement(4377..4586)
                     /gene="copZ"
                     /locus_tag="OUE31_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HCU0221907.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4599..5039)
                     /locus_tag="OUE31_000878"
     CDS             complement(4599..5039)
                     /locus_tag="OUE31_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HCU0221908.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5113..5652)
                     /locus_tag="OUE31_000879"
     CDS             complement(5113..5652)
                     /locus_tag="OUE31_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCU0221909.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(6267..7733)
                     /locus_tag="OUE31_000880"
     CDS             complement(6267..7733)
                     /locus_tag="OUE31_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0221910.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(8044..10125)
                     /gene="cadA"
                     /locus_tag="OUE31_000881"
     CDS             complement(8044..10125)
                     /gene="cadA"
                     /locus_tag="OUE31_000881"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCU0221911.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(10650..11009)
                     /locus_tag="OUE31_000882"
     CDS             complement(10650..11009)
                     /locus_tag="OUE31_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HCU0221912.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(11039..11380)
                     /locus_tag="OUE31_000883"
     CDS             complement(11039..11380)
                     /locus_tag="OUE31_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221913.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(11377..12051)
                     /locus_tag="OUE31_000884"
     CDS             complement(11377..12051)
                     /locus_tag="OUE31_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCU0221914.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(13227..14525)
                     /gene="asnS"
                     /locus_tag="OUE31_000885"
     CDS             complement(13227..14525)
                     /gene="asnS"
                     /locus_tag="OUE31_000885"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HCU0221915.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(14565..15755)
                     /locus_tag="OUE31_000886"
     CDS             complement(14565..15755)
                     /locus_tag="OUE31_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCU0221916.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(15776..16303)
                     /locus_tag="OUE31_000887"
     CDS             complement(15776..16303)
                     /locus_tag="OUE31_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HCU0221917.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(16350..19139)
                     /locus_tag="OUE31_000888"
     CDS             complement(16350..19139)
                     /locus_tag="OUE31_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCU0221918.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTSMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     ETAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHTLPKKVPIKELAMEKI
                     YQDIHEFLKKNEEGS"
     gene            complement(19286..19486)
                     /locus_tag="OUE31_000889"
     CDS             complement(19286..19486)
                     /locus_tag="OUE31_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCU0221919.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(19937..20257)
                     /locus_tag="OUE31_000890"
     CDS             complement(19937..20257)
                     /locus_tag="OUE31_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221920.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(20760..21878)
                     /locus_tag="OUE31_000891"
     CDS             complement(20760..21878)
                     /locus_tag="OUE31_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221921.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            22351..23658
                     /locus_tag="OUE31_000892"
     CDS             22351..23658
                     /locus_tag="OUE31_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCU0221922.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKIAGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLSADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            23779..24978
                     /locus_tag="OUE31_000893"
     CDS             23779..24978
                     /locus_tag="OUE31_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCU0221923.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLIFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADENVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(25003..26271)
                     /locus_tag="OUE31_000894"
     CDS             complement(25003..26271)
                     /locus_tag="OUE31_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HCU0221924.1"
                     /translation="MEKQLPSPVRILMYMLKWLVITAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLLYLLPISGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKAEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAYAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(26434..27081)
                     /locus_tag="OUE31_000895"
     CDS             complement(26434..27081)
                     /locus_tag="OUE31_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HCU0221925.1"
                     /translation="MEQTMKPYQYFFIKREVDQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDVLGYEPPEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIDKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(27488..27991)
                     /locus_tag="OUE31_000896"
     CDS             complement(27488..27991)
                     /locus_tag="OUE31_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCU0221926.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TKLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(28114..28878)
                     /locus_tag="OUE31_000897"
     CDS             complement(28114..28878)
                     /locus_tag="OUE31_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HCU0221927.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            28985..29260
                     /locus_tag="OUE31_000898"
     CDS             28985..29260
                     /locus_tag="OUE31_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HCU0221928.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            29698..30648
                     /gene="yidC"
                     /locus_tag="OUE31_000899"
     CDS             29698..30648
                     /gene="yidC"
                     /locus_tag="OUE31_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCU0221929.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(30827..31801)
                     /gene="lacD"
                     /locus_tag="OUE31_000900"
     CDS             complement(30827..31801)
                     /gene="lacD"
                     /locus_tag="OUE31_000900"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCU0221930.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKMPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLKETATPVYVDR"
     gene            complement(31798..32256)
                     /locus_tag="OUE31_000901"
     CDS             complement(31798..32256)
                     /locus_tag="OUE31_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0221931.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(32253..33419)
                     /locus_tag="OUE31_000902"
     CDS             complement(32253..33419)
                     /locus_tag="OUE31_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HCU0221932.1"
                     /translation="MAGKGTVLADNEAVDNLEPEVMSGANFGRSIYKNLMNCVSHMLP
                     FVVAGGVLIAISFAVWGIYSFDPDHAQYNATAAMLKTVGDAAMGMMVPVLAAYIAEGI
                     AKRPGLVVGFVGGIVVMNGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIF
                     LYPVIGVAFIGIVMSLLAGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGP
                     INKAAYVTGTALLAQGNTTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNF
                     ILGSTHITEGAIPFAAKDPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVT
                     GKIQWVTAILIGSIVGGVILGLIQKKRVTDEDKKMDNKAANRTVIEEGRAGGLS"
     gene            complement(33522..33715)
                     /locus_tag="OUE31_000903"
                     /pseudo
     CDS             complement(33522..33715)
                     /locus_tag="OUE31_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002607937.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(33697..34647)
                     /gene="pfkB"
                     /locus_tag="OUE31_000904"
     CDS             complement(33697..34647)
                     /gene="pfkB"
                     /locus_tag="OUE31_000904"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCU0221933.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIREERFERWENIN"
     gene            34790..35539
                     /locus_tag="OUE31_000905"
     CDS             34790..35539
                     /locus_tag="OUE31_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCU0221934.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPNYEVRSRLPLQIIARILLDAYVLRMGEN"
     gene            35805..37289
                     /locus_tag="OUE31_000906"
     CDS             35805..37289
                     /locus_tag="OUE31_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HCU0221935.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIAILLA
                     QHNQVTAVDIIPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGATAYKKADFVV
                     IAAPTNYDSKQNYFDTSAVESVIELVLAVNPKAIMVIKSTVPVGYTESIREKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQNDKTLLEASHTFADLLQEGAIKKDIETLLM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKELNTKDIINGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDIPQNMMSAIVDSNRTRKNFIADRVLQKTGYYSYDDDN
                     TFDLSLEKEVIIGVYRLTMKSNSDNFRQSSIQGIMKRIKAKGATVIIYEPTLKDGSTF
                     FGSKVINDLEKFKSISHSIIANRYDSILNDVKEKVYTRDLFQRD"
     gene            complement(37404..37538)
                     /locus_tag="OUE31_000907"
                     /pseudo
     CDS             complement(37404..37538)
                     /locus_tag="OUE31_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209342.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            37611..38737
                     /locus_tag="OUE31_000908"
     CDS             join(37611..37839,37839..38737)
                     /locus_tag="OUE31_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCU0221936.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PNQSTGLTGKEAADLRKENARLKEELEILKKAGSHILSKDLKSLVRFIEKWCKEYTVS
                     LLCRLLEIPRSVYYFYKNKSLTATEVRNNQLKKKISTIFFDHKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRPVQPVVLKENILNQDFSTKTICEKWVAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVLQTFNQAKQRYHIPEGMIL
                     HTDLGSQYTAIEVENWLENNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTTYSDF
                     EEANRSLFSYIEGFYNRNRIHSSIHYLTPQEFEDLETEKMS"
     gene            complement(38634..39023)
                     /locus_tag="OUE31_000909"
     CDS             complement(38634..39023)
                     /locus_tag="OUE31_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="HCU0221937.1"
                     /translation="MKIAVAGTGYVGLSIATLLSQNHEVMAVDIVPEKVEKINKRISP
                     IQDEYIEKYLKEKELKLTATLDAEAAYKDADFVVIAALDLSQYLGHILVETAKTFSLF
                     LNLQTPVELSNESNYGFDYDYKILQCS"
     gene            complement(39047..40243)
                     /locus_tag="OUE31_000910"
     CDS             complement(39047..40243)
                     /locus_tag="OUE31_000910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221938.1"
                     /translation="MKKKIFFDMILNIVATSIPTVVLQLLILPSLSNYMDGNAYGLMV
                     TILAVLNVVPSTIGNVLNNVRLLHEESYKKDNEQGDFQILLTIFQAINLLIMVTVSIY
                     YLGTKDITGILLLIAVGILWLGREYHIVAFRLKLDYIAILVNNLCLVAGYGIGYIFFM
                     KNGYWQIIYLLGYILSYLHIVIASPIVKEPFTKTKRLRIVFNDSAFLLISNVLARAIN
                     YADKILLYPLLGGTMVSVYYAATVFSKVVSLAITPINSVALSYLSKINKKTNSLFKWT
                     YIVGIVVCGIGYIMTIILSRPVLSILYPKYVDAAMQYIWITSGTIVVSVLTSMITPFV
                     LRFFDIKWQIWINGITTIMYIIISLSLLKLGGLMGFCIGALLANIIKLLITTYVYLKK
                     TSRSSE"
     gene            40433..41752
                     /locus_tag="OUE31_000911"
     CDS             40433..41752
                     /locus_tag="OUE31_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HCU0221939.1"
                     /translation="MTSLHKNQVKFNSNLTISHTGGRLSSDSGLVLVQEVMNTFGFSH
                     VAKQWLHIKDKRVYFTHDNLAILEQLIMQLIAGYSADSSANLLRQDPVFQAVLGKKEL
                     ASQSSISRFLDRFTEENMDQLQALNQSLIDKARLIRNDTELIIDVDSTHSDTFGRQEQ
                     TDYNAHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKAFIDPLLHHYKSTLPH
                     TEILVRGDSGFATPEVYESCEATESQYVIRLKSNRRLSQLAEHSVLYGDNKKWEDREI
                     QYFSLPYQAQSWSKPRRVCIRSIREAGELLFHHAFIVTNLSDNVSPEVIFSLYGKRGT
                     MENFIKEAKSGFYFDKTDSPRFLENHVRMMISVLAYNLVNFLKTIGFEQVNRGMTIHS
                     IRLTLLKVAGKLVKTGRQVYLKLSSYHVYQTEFYKVFERLRRSRQWI"
     gene            complement(41949..42665)
                     /locus_tag="OUE31_000912"
     CDS             complement(41949..42665)
                     /locus_tag="OUE31_000912"
                     /inference="COORDINATES: protein motif:HMM:NF014571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAC(3) family N-acetyltransferase"
                     /protein_id="HCU0221940.1"
                     /translation="MDEIGVKKGDVLIVHASWRALYMLDMCPEDVIRLLLDKIGKEEG
                     TLLMPAYGEDNSSFDLNKTKSVAGVLSESLRNYPGTMRSCFPKFSMCGYGKHAEEILS
                     KHKNSLYQFDENSPYSIATKEYNAKVLLMGMGKRPHKITVFHCASYALKNSIDYYKEC
                     YSNYKTAYVLSDVGGTVQYLDRMPGYNNNKHVFKKLFESIPNKCIVSKKRLNLIIFNA
                     IDAYNVAWEFCKNGGKIYTT"
     gene            complement(42771..44126)
                     /locus_tag="OUE31_000913"
     CDS             complement(42771..44126)
                     /locus_tag="OUE31_000913"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HCU0221941.1"
                     /translation="MLTNIKNLLLKPNKVLQSIYIIAFRVLLDYMYCNIVSPLYSYIG
                     MTAEQSTFYYMVSWIMVICYILMMFTIIDVEKNGAVVLSIILICSAVPTTTIVAFLGH
                     NLEFAVLNVLYWFFMVAFYKHKGRKIVLGKNTIKRSSLLIYAVFLFFAAVLLLICVAY
                     TGIHVSFNLYDVYGTRAAFKSDKLPTILQYLFSACIIVFPVIIVYGLNKKKRILALAA
                     TICQLLAFFADGRKSTIFVLIATILGYYFIHNLTARMIPAIMMGVTVIGFIEKICIGT
                     ENFINLVARRLFLVTAYLQYAYFDFFSNNVKDYFRQSIVGRLGFSSPYTKDIPTLVGG
                     QYYVNNSYANNGLFADAYSNFGAVGVVILPILIVCALKLLDRVCEGLTSGICMGIIIV
                     SAYTLLSSSFFTVMLTHGFLLGCIIIYLVPRFSYQRDVVVENEGMKGKYDDKKSITKY
                     S"
     gene            complement(44120..45247)
                     /locus_tag="OUE31_000914"
     CDS             complement(44120..45247)
                     /locus_tag="OUE31_000914"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCU0221942.1"
                     /translation="MKILHINCNYILSSLHQCLIEKLNAAGFSNDVFVATYDKKRSIV
                     NTKEYVKIEECFNKWDRINFDFKQAKILKKIEEDFDLEKYDCIHAYTLFTDGNSAMKL
                     SDKYGIPYVVAVRNTDVNDFFAKRFLLRNRGIEIMRKAQKVFFLSNVYRETVLNNYVP
                     EKYRNEIYEKTVVIPNGIDDFWFENQPEDTIKKSEKKDFIRLVYAGRIDRNKNIPTTQ
                     KAMKILKKKGINSELLVIGKVDDKTELKKIISEDSTCYEDAKPKEQLIDAYRNADIFV
                     MPSFTESFGLVYAEAMSQGLPVIYSKGQGFDGQFAEGVVGYHVDAHDPEELCENIIKI
                     LKRYNEFPEACMQASKKFRWDNLSKEYVKIYQEIMENKNSC"
     gene            complement(45270..>46567)
                     /locus_tag="OUE31_000915"
     CDS             complement(45270..>46567)
                     /locus_tag="OUE31_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HCU0221943.1"
                     /translation="NGEEKIAIVGLGYVGMPIAVAFAKKAKVIGYDLNEKKIELYKSG
                     IDPTNEVGNEGVKLTTVEFTSDEKKISEAKFIIIAVPTPVNTDHTPDLTPVIGASEIV
                     GRNLTKGSIIVYESTVYPGCTEDVCIPILEEKSGLKCGKDFKVGYSPERINPGDKVHR
                     LENIHKIVSGMDEDSLNEIKNVYDLVIEVGTYPVSNIKTAEAVKVVENSQRDINIAFM
                     NELAMVFDRMGIDTNEVVDGMNTKWNALGFRPGLVGGHCIGVDPYYFTYEAEKLGYHS
                     QIILNGRIVNDSMGAYIADTAVKTMVVAGQSPKKSKVVILGLTFKENCPDTRNSKVED
                     IIKQLKTYDIDPVVVDPWADEKDAFREYGVKLSELENAKNADCIIVAVAHNEFKKMSL
                     DEIKALFKDCPDNEKVLLDVKGLYSVSDLKKSGMNYWRL"
BASE COUNT        13899 a         9747 c         7728 g        15193 t
ORIGIN      
        1 cattattatt tgattttcaa tgtcaaagca ttcagcgcta cgactaccgt acttaacgac
       61 atcaagacag caccaactgc tggacttaat aggataccaa ttggtgcaag tattccggct
      121 gctagtggga ttgcgagaat attgtaccct gctccccacc agaggttctg gatcattttc
      181 tttcgcgttt gcttagctaa atcaaggaaa tgcaaaatat cttttggatc gctgtttgtc
      241 aagacgacat ccgcagaatc gatcgcgata tctgttcctg cacctattgc catcccaata
      301 gaagcacggg ctaaacttgg cgcatcattg atcccatcac ccaccatgat tacttttttc
      361 ccttggtcaa gatatttctg gacaacagct tctttatcat ctggtaataa accgccgtaa
      421 tattcttcga ttcctaaata atctgctact gcttgagcag catttttatt gtcgccagta
      481 agcatgactg gagtgatttt cctttccttc aatgttcgga taaactcttt tgcttctgtt
      541 tttattacgt cacctaaagc aacgattgca gctagatgat tttctaaaat caggaagctg
      601 atggtatttc cttgttcttg gtaaggtttc aataatgctt gttctacgtt taatccgaga
      661 cgctcaactt ctttttcatt aactattttc acttgttggc ttttgactgt tgcctctagc
      721 ccaactcctg aaagattttt tagattttcg gcttgataag gcttgatttc atgttctttc
      781 aaataattca taatgccaac agccaatgga tgattggcat tcgcttccaa tgctcctaaa
      841 tattgaagga tttcattttt attgaacgca tcatcaagaa cttcgacacc cgttaccgta
      901 aattttcctt ctgtcagtgt cccggttttg tccaacatga tcacatctaa atcattggct
      961 tgctccagtg cattgcggtt tttcaatagc aatccgtttt tagcggcgat cgatgtggaa
     1021 cgagcaacaa ctaatgggat agctaaacct agagcatgag gacaggcgat gataaagaca
     1081 gtcaccatgc gttccaatgc attaggaaga tctgtcaaga acaaccatgc gataaatgcc
     1141 aagataccga cagttaaggc aacataaaac agccattttg ccactttgtc tgataatgac
     1201 tctagcttag atttttctcc ttgtgctttt cgcaccattt ccataacctt cgctagatac
     1261 ccattttcac cagttccagt tacttcgatt tcgatcgttc catccccatt gatagaaccg
     1321 ccgatcactt tgtcattggc tcgttttttg attccttttg attcgccagt cacagctgat
     1381 tcatcaacga ttgtttcacc tttcaagata acaccatctg ttggcatttt gtcaccggaa
     1441 cggacgatca aatgatcgcc ttcctttact tcttttagtg agactgtctc ttcttttcct
     1501 tctttcgtca agcgtttcac tgattctggc agtaattctg ctagtttttg taaagcattg
     1561 ctggcattcg aaacagcgtt catttcgatc cagtgaccta gcaacataat gacgatcaat
     1621 gtagctaatt cccagaagaa atccatgacg tgcgtatgag gattgatcag attcgcgata
     1681 aacgaataga cactataaat atatgcaact gtaatcccca tcgcgatcag cgtcatcata
     1741 gcaggacttt tttgtttcaa ttccattttt gccccgctta aaaatggctg tccgccatag
     1801 ataaacagta tagttgctaa gatcagtacg agccaatccg aaccaggaaa tgttatctgg
     1861 aagggaaatt ccattcccat cattggtgaa aaaagaatga ttgggatagc taggataagc
     1921 gatagccaaa atttttgttt gaaattcccc atgtgcatgg aatgatccat accgccatga
     1981 tcgtgatcca tgtgcatcga atggtccatt tgtttgctgt ccgctatatc tccatggtta
     2041 tgttccatat gcatcgaatg gtccatctgg ctatgatcat gcttcatctg tttttcgttt
     2101 gaatgagcac tttctttgtt tcctgcttct tttttatgct cctgtttttt ctccatatcg
     2161 ttcccgttca tttttactcc atcccttctc ttactttttc atgtgccgat ttaagctcag
     2221 ggagttcaac aatacactga cggaactaaa cgccatcgct cctcctgcaa tgattggatt
     2281 caaaaagcct aatgcagcaa aaggaatgcc aatcgtatta tagacaaaag cccagaaaag
     2341 attttgtttg atttttctca atgtcattct agacaactcg attgtttgag caatggacgc
     2401 caaactacta ttcatcagcg ttacatctgc tgtttccatc gcgatgtccg ttccacttcc
     2461 cattgccata ccaacatcag ctaatgcgag agctggcgca tcattgattc catcgcctgc
     2521 cataccgact tttttgccat ctttctgcag tttttccaca taggctgctt tatcctctgg
     2581 aagtacttca gcaaagatat gctttggatc aataccaact tgtttaccaa tcgtttcggc
     2641 tgccagtttg ttgtctcctg tcagcataaa aacatctaat cctttattct ggagctgctt
     2701 gattgcttgt ttgacttcta gtttgatttg atcagccacg gcaatcaacc cgatcacttg
     2761 cttttcatca gctaaaaaca tgactgtttt tccctgctgt tctaattcta acgcgttttc
     2821 ttggtattca tcaaatgata ggttcaattc aattaatcgt ttacgtgtac ccgcaaaata
     2881 gcgtactccg ttaatcgtac cgctgattcc agcacctggg tgggctgtaa aatcaatcat
     2941 atcgtatgtt gctgcttctt gcagttttcc gtattccacg attgctttac ctagtggatg
     3001 ttcagaagct tgttctaaag tataaaaaat agataggact tctttagaac cgactagatc
     3061 tgtaactttg ggctttcctt ctgtaatcgt tccagtttta tccaaaacaa tgctgtctaa
     3121 gtgagcagct gcttctaatg cttctccgcc tttaattaaa attccatttc gtgcaccaac
     3181 acccgttcct accataatag ctgttggagt cgctaaacct aatgcacatg gacacgcaat
     3241 gactaataca gagacactat ggatcaatgc gagttgccaa tcaccagtga tcaaacctgt
     3301 agctatgagc gtgataaacg cgatgactaa tacgatcgga acaaaaatcc ctgagatccg
     3361 atctgcgatt ttttggattg gggctttgct cccttgagca tcttccacca tttgaatgat
     3421 ttgcgctaat actgtctgct tgccgacttg tgtaacttcc atgtgaagta gaccattcgt
     3481 attgattgtc ccgccaaaga gcgtgtcatc cggattcttt tctacaggaa gattttcacc
     3541 agtaagcata ctttcatcta tcgcactgct tcctgaaata attcgaccat ctgctggaat
     3601 ctgctcacca ggacggatga ctagttgatc accaacgact acttcttcaa tcgctaacgt
     3661 ttcttctttc ccgtttctta tcacttgggc ggtttttgtt tgaagagaca tcaattgttt
     3721 gattgcatta cctgttttcg tttttgctgt atgttccaaa tatttgccga gcaaaatcag
     3781 cgtgatgatc atactgctgc tttcaaaata aagatcttgg gggtgtccac ggaaaaatcc
     3841 gttgtaaatg ctcaatgcaa aggcagccga tgttccaatt gctaccaata catccatatt
     3901 tggtgctttc gtcttgattg catggtacgc acctttataa aaacgagcac cgacataaaa
     3961 ttggacagga gcagacagca ctaactggac gattggaaaa tgaaaaaagt gaacaatcgc
     4021 cgcatggctt cctaacatca tagcaatcat tgacaacatc aacggcaaag tcaaaaccgt
     4081 actcaatata agatcgaata gcattttttt caaatacgat tgcttttctt ctgcaatttt
     4141 ttgtttgtgg gcttcatcgt acaaaattgc accatagccg atgttttcta cgctttggat
     4201 taatttttca gtggtcgtcc cttcatattt gacacttgct ttttcagtgg ccaagttgac
     4261 tgtggcattg accacaccag gttgtccgtt cagctctttt tcgatcctag cagaacaatt
     4321 tgcacaagtc atacctgtaa tgacgaacgt atccattttg gtttctgctg ttgccatcaa
     4381 atcacctctg ctttataacc caatccattg attgcttgac aaatcttttc ggattgaact
     4441 tttgtttcat caaacttgac cgtaccgttt gcttttttca aatttacttt cactttttgc
     4501 acgccgtcaa gtgcgcttac tgtttcttct actcttgctg cacaatgatt gcagctcata
     4561 ccttcgattg aaaattgttg tttcattttt tcttcctcct attgatgttg tttacattca
     4621 cattgacctg ggatacagtt acattcgatc gtatctactg gttgcttttg ttccagttgt
     4681 ttcaaaatct cattgatatc ttcttgagtc aaagtggctt cttctactag atccgcaatc
     4741 gtctctccaa tcctttttgc acagatatgg gaaaaaagat tttccgtcgc actgcgaact
     4801 gtttccatct ccgagacagc tggatgataa atgaattttt ttccttcttg ttctgtccag
     4861 atcacttctt tttttaccaa acgacccagc aaagttttga tcgttgctgg tttccaatcc
     4921 atcgaatcag ctaagatctg cgtgatttct tgggctgtcg tctgtccaag tgtccaaata
     4981 acacgcatga tctcccactc tgaatcactg atctttactg gcgttttgac tttttccatt
     5041 tatttcacac ctttcgttta caaatgtaat cattatctta tgaatacaga ttacacttgt
     5101 aaacaaaaac tgtcaattat ttttgctctc tattttcaat ttagttaaaa attcttgttt
     5161 ctctcgtctt gttttaagga tgatcagttt atttcttgca ttagctactt ggatcagctg
     5221 ctgtattttc ggttcattgt tttcttcaaa atgccagata aaagataaaa attctaagta
     5281 ttccctgttt agtttctccg aaaatgattc aggcatatct ggccgagatt ttttgtttat
     5341 ctttcttttt agagaacgcc aaactactcg gtagatggcg agataacgcg gcactttaag
     5401 ccaaatgatc ttatctgctt ctttaatcct ttcctctaat gtagaagtat aatttccttc
     5461 aacgatccat gacggattag ataccataaa caattgctgt tcttgcaaaa accacttttt
     5521 tgcctgaata ctgtagtctg ttgtatgcca taaaaggtct agcggcagta gcggaaagtc
     5581 ggtgatttct ttgatcttcc ttgcgagggt cgattttccc gacccacttt gtccaatcac
     5641 gatgatcttc attcttctcc ctcacttctc tttggaattt ggttcgatca taccacttat
     5701 aacgccgcaa aaaaacaagg gactgtgaca aaagtcgtgt caaagtccct tgtttcgaat
     5761 aaatggtgtt caatcagctg accttcagca ttagctcaaa aagcggcaaa atatgaggag
     5821 ctatttttcc gtttgtttct ctaatactca ggtcaaatcg ctgattttac aacctcttcc
     5881 ttaaacggtg ttctcctgcc aacacctcgg tcacaagtca caatagtcaa caaacatgag
     5941 aagttgtttt ttgaaattgc tccttgtgac tcggagttaa acggcaggct cactacctct
     6001 ttcttaaacg gtgttccaaa gcttgcatct gcggtaataa gcccagccaa acgaaaaata
     6061 tgaggggcta tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac
     6121 ctctgattca cggtgttcca gaagtagctt cttcgaaaaa caagccgaaa cttcacaaaa
     6181 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
     6241 aacctcttgt aacaagtatt tctattttaa ggctgaacca ctgtttctgg ttcagtgatt
     6301 tctttgtttt tgtctcgacg agcaattgct ggcaagatca tacctaataa gatcaagacg
     6361 attggtgtga tgatattcgt aaataattgg aaccaccatg ctttaggatc agcagtataa
     6421 tctacttttg gcaccattcc taggatacat gcaaacgcag tgaaggcaaa gcaccaagca
     6481 ccaaagataa aaccgatttt tggattttta acaaatttat attcagaatt gaatttctta
     6541 taagctttat tcaacatcat atatgccaag aacacccata ggtaacgcat tggcatgaca
     6601 actgagttca agttcgtcaa ccattttact aattcattca tatctttgat accaaaaatc
     6661 ggcaacaaaa taatgattcc tactagtata cctgtcagaa gataaccatt caccaatgta
     6721 cctttacgat tacgtttacg tagccagttt ggtacaaatt ctggatccgc atctgctaac
     6781 aagattttta gtggtgcatc aattgaaaag gctaatgcgg agatttgtcc aatcatgttt
     6841 gtcaatgcgt aaatgatcat caatgagtta ccgataccat agtaattacc taaaatttga
     6901 aaagcactgt atgccccatt tgccatcaag tctttaggaa tattatcact agcaaacagc
     6961 atacccattg cgactgagcc taatacagca caaatcccta ccattgctgc taagaagatc
     7021 atccctttag gaaattcctt tgcaggattt cttgtagagt tgacataagg ggatattttt
     7081 tccgcccctc caactgcaaa tactagcatc gaaacggttg tgaaataact gaaatcaaat
     7141 gttggaatat atgttttcac ttgattcata tgtggtgtgg caaattccat cgttggattg
     7201 atgaacggtg ccgttacagc taaaagaata aataagatcg acatgacgaa catcgctgtt
     7261 ccggccagtc cgccaatcac tttcaaagta gaaagtcctt ttgttgataa atataaaaag
     7321 gcaagaaata taataagtga aataactgct accatttgta ctgacatcgt atttacgata
     7381 tttccatttc cttggactgc ccaaccacca gcaatcagaa ttgcttgagg cttttgtgcc
     7441 aaataaggaa tatggacgac ccagtaagtc caagcggcat agtatgccag tcgtttatta
     7501 gatgtcgtat tttcgaccca tgaactgacg cctcctttac tatccttgaa ggctgatcct
     7561 aattgtccaa cgatcaatgc gtatggaata aaataaatgg ccaaaatcaa tagccaagag
     7621 gtgacaactg atactccttg ctgagcatag ttattaacta cattccccat gccccaaacc
     7681 atgttaaatg caattaacgc aacagtaaac cagcgtaatt gtttgttgtt cattcgttct
     7741 ctcctttatg ataaaaattt gttatccaga tgtaatcata ttcaattttt aacaaactta
     7801 caagacagtg ttattttatg tgtgtattct tttatttaat acacatcgtt ttttcatatt
     7861 ttttccatca aaaaaataag ttattttctt ttatttcatt gaccttattg aatttcaagc
     7921 tattttgaat tttctgcaaa attaaaaaca ttagttattt tataatccta tctattttct
     7981 ttacattttt cattaagaaa aggatataaa aaaaagagga cgttcattcg tcctcttcat
     8041 tgatcaacgt ttatttttta catgcaagct tcgcatggca ttcaaaacag ctaatactgt
     8101 caccccaaca tctgcaaata ctgcatctcc cattgatgca aaaccaaaag cacctaaggc
     8161 aagtaccaaa atttttatcc caatagcaaa gacaatgttt tgtttgacga ttttcaatgt
     8221 tttctttgct aaatggattg cttctgcaat cttcgatggt tgatcattca tgatgactac
     8281 atctgctgct tcaattgcag catcgcttcc caatccaccc attgcgattc ctacatctgc
     8341 tcttgctagc accggtgcat cgttgattcc atctccgaca aatgcggtct ttttattgtt
     8401 tctttgtaag atttcctcta accgctgcac tttatcttca ggaagcaatt cgctatatat
     8461 cttgtccacg cctacttgct tcccgatatg atcagcaatt tttttcgagt cgcccgtcaa
     8521 catgactgtg ttcttcacac cagcctgttt taattgaacc aatgcgtcta cggcatcttc
     8581 tttcaaggta tctgcaataa caagataacc actgtaactt tgatcgatcg ctagataaag
     8641 caatgtaccg atttcttgac ttaaaggaaa agagatttca aatctttcca tcaatttgtg
     8701 attacctgct aatacttgtt tgccatcaac ttcagctaag atcccttcac ctgcaaattc
     8761 ctggatatta gttgttggta aaagcggacc tgcgtagcct tctaaaacag attgagcaat
     8821 cggatgtgta gaaaactgtt ctgcactcgc aatatattgc atgaatttct ttggatcgat
     8881 ttttgtatcg atcgtctgga tcgaaaagtc acctttcgtt aatgtgccgg ttttatcgaa
     8941 taccactgtc tcggtttgcg caagcaactc caagtaattt gaacctttta ctaatacacc
     9001 gattttactt gcgcctccga taccgccaaa gaaactaagt ggcacggaaa tcactaatgc
     9061 acatggacat gagatcacta aaaatgtcaa tgctcgatag atccattcag aaaacgccgc
     9121 tccagaaaca acaagtggag gtaaaacagc taataaaacg gccaatccta caacgactgg
     9181 tgtgtaatag cgcgcgaatt tagtaatgaa attttcagct ggtgcttttt tactgctggc
     9241 attttctact aattctaata atttgctgat agtagaattt tcataagatt tttctacttg
     9301 aactaaaaat ggtttatttt tattgataaa tccgcttaat actgtttcac caacatatac
     9361 agatttaggg actgattctc ctgtaagtgc tgacgtatcg actaatgatt ctccttcgat
     9421 gatcgttcca tctaacggta cacgttcacc aggcttcaca agtacaaact gaccgatctg
     9481 cacgtcttca gggttcacgg tcatcaatcc ttccgtcgtc tgcacgtgag ctgtttctgg
     9541 acggatcgcc atcaattcgc gaatcgattt tcttgaatga ctgactgcca atccttggaa
     9601 atactcgccg atttgataaa atagcatcac tgctacggct tctggatatt caccgatcaa
     9661 catagcgcca atcgtagcaa cagacataag aaaattctca tcaaagattt ttcctttgac
     9721 gatattcatc actgccttct tcactacatc atatcctatc agcagataaa tcaataaata
     9781 ccctatcaag cgaattggtt cattaaaatc aaataatagc aataaagcga tacctgcaag
     9841 ggaaaataaa atccggaaca gcgtatttct ctctttttca tttccatgtt cagatacttt
     9901 ttccttatct atttctgtta ctttgacatc tggttctaat tccttcacta ctttttttgt
     9961 ttcttgttca atcgtagcca aatgatcttc ctctgcgtca atcgttagtt ttccagaagt
    10021 gaagtttacc gttgcttcct tgactccatt gatcttctga actccttttt cgattttcat
    10081 tgcacagttc gcacaatcta aaccttctaa tctgtaactt ttcattttaa tgacctcctc
    10141 gcctcaacat atgaatatct cttcataact aattataaat gaatggttat tcatatgtca
    10201 aggtatccga aagaaaaaat gaaaaacatc tgcatcggaa aatttcttcc atacagatgt
    10261 tttggcttat tctttctttt tctcttcgat cattgcccct gctcttatcc aacccgcact
    10321 tgccttcttg atcttgacag gatagcaact aagtttgaag cctgttgctg gcaatttgtc
    10381 taaattcatt aatttttcga taggacaata tcttttttca atccctgcaa aatgtccttc
    10441 ccagatattc gaagctccac tacgctttca aaaatataga aagagttctt taatgaaaat
    10501 tatttcaact ttccataaac agtaatccca tataaataaa agacgtaaaa gtcacatggg
    10561 agaacttata caggaaaaca catagagtca ggtgaaatac atgtatccca cctgactcta
    10621 tgcgttttct aacctttatt attctctttt tatacaattt ctgcaccgaa tggcatcaac
    10681 gccaatcgag caagtttgaa agattgcttg gcaaaaggta tccctatgat cgtgatacat
    10741 agaaggatgc cgctgacgac atgtgcgaga gcaattggta ggcctgaaac gatcagccag
    10801 atgatattaa cgatcaatga catgccagac tggtgataaa ttacttcttt gccaaaaggc
    10861 gcaaaagaaa gggaggcgat cttaaaacat tgcataccga ttgggatacc tatgatcgtg
    10921 atacaccaaa gtatccccgc tgctaaccag ctaagaccac cgattagtcc gccgaatata
    10981 aaccagatga catttcctaa acaactcatt gtatttctcc ttctattact gtttttgatt
    11041 aaaactgggc aaaaattgat tttattcttc tttttttagc ttccagcatc aagtattctg
    11101 caaatttttt ttggatttct tccgtatttt cttttgttac taatgtgtgt tggattagtt
    11161 ttcctgatgg tcgctgatcc acccgttctt ctgactgttg cacgtccgct tgcgcaaatc
    11221 cgataatccg tttttctttt gttacagcaa cgagcaatag tttattctta tcatttaggt
    11281 cagctgccgt ttttgctttt acgaatgatt ctggatgatc agtaatcagc tgattgattt
    11341 gaggtaaatc ttcttttact gcccaccgta tttccatcat ttctcacttt tctttcgctc
    11401 atttttatct ccactaaaaa aatcgactgc ggcaattgca tctatccagc tttgtgcaat
    11461 gatctcatgt ccgccaatcg ttgggtggac cccatcttct cttgtatatt tcgaaaaacc
    11521 ataagcaatc cctaaagcat tgaatatgcc atctaaagga accagcaatg cgccatattc
    11581 cttagcaagt ttacgaacaa tttggatttt agggtctaag tctttacgcc agccatgacg
    11641 gtcgtcggtt ataggaagta caaacggctc catcaagatg atgttgcaga tttccgctgt
    11701 ttgaagttca tttagtaatt ttcgataaac ggattcaaat tgctgcgcag atttctcagt
    11761 tccgaatata gcctgatcgc tagtattatg ccaggtatca ttgattccga tcaaaatcga
    11821 tacatagtca ggttgtaaag ctaaacaatc ttcttgccag cgtacttgca gatctgcaat
    11881 tttgtctcct cctatcccac ggttcatgca ttcaaattcc atcgttggat attgggagat
    11941 tagttttccg gcaatcaaaa gtggataacc tttacctaga tcagttgctt ctgctcggtc
    12001 tcttcctgcg tctgtaatgc tgtcaccgat aaataatata cgttttttca tttgtcaaaa
    12061 actccttttt gaataaaacg atgattttct tccttatatt atcccataag ccctatcaag
    12121 acgaaagaga aaatatatgt ataaaaaatg acaccagcct agtcccttca atcaattgaa
    12181 tgaacgctca tcaagtgtct agttttttat actttttttc ttaacgtgcc ggattcccct
    12241 tgattccttc gttgtttggt ccagagaaat cgatcacacc taagcttccg tcaatcagac
    12301 cactgatgac gccatcagaa catatattta taggctcatc taagacttcc agtaaatgtt
    12361 cttttactaa tatctcttct agattgcttg ggatagattg gtcataactt tatctggtcc
    12421 gatgatttca aggatgaatt aaacttacat atggatcatt gcatgctgaa aatacggacc
    12481 tactccatct tcgaatgtta ctattagttt gttttcaggt actagatgct gctttatttc
    12541 aacagcagaa gcatcatcaa atcagatttc catttgaata accttctttg tatatgtttg
    12601 attgattgcg atttcgttat agaaccttgt gaatcaaata gcaatttctt ttgctttctt
    12661 ctcttgtctg ctggaaactt cctttatccc gtattttaaa aaaagaactg cgagagttcg
    12721 cagttctttt ttttaaataa acgttgctct ccggccaact cctcggtcac aagtcacaat
    12781 agtcatcaaa catgaaaaac tgttttttga aattactcct tgtgactcgg agctgaacgg
    12841 caggcgcaca acctcttgat ataaacggtg ttcaatcagc tgaccctcga tattagctaa
    12901 aaaaacggta aaatatgaga agctattttt ccgttttgtt tctctaatac tcaggtcaag
    12961 gcactgattt cacaacctct tccttaaacg gtgttcaaaa gccagtttct cgatattaag
    13021 ccaaatttat gcaaaaatgt ggaaagccat ttccacaaaa tttttcttaa tactcgaaac
    13081 taaacagctt tttcacaacc tctccactaa acggtattca aaagcttaca tctgcggtaa
    13141 taagtcccgc caattcaaaa acatgaacag ctgtttttgc ttggctgttc taattacttg
    13201 atgcagaaca gctttttcat cacctcttat ggataaattc ggttcaacaa acgtgggaat
    13261 ggaatagctt cacgtacatg gtcgatacca gcaatccaag tgactgttcg ttcaaggcct
    13321 agaccaaaac cagagtgcgg aacagaaccg tatttacgta gatcaagata ccatgaatat
    13381 tctttttcat ccaaaccgtg attacggatt tgttctagca agaaatcata gtccgttgcc
    13441 cgttcgcttc cgccaataat ttcaccgtaa ccttctggtg cgatcatatc tgcacaaatt
    13501 accacgtctt ctcttgttgg atgtggtttc atgtagaatg gcttgatagc ttttggatag
    13561 tttaggataa agacaggctg ttcgaatgaa ttcgcaatga acgtttcatg aggtgaacca
    13621 aagtcttcgc cccattcgat gtcatcaaat ccatttttct tcagtaattc gattgcatca
    13681 tcgtaagtaa tacgagggaa tggcaatttt gtataagttt ttaagacttc tttgtctcgt
    13741 cctagtacat ctaatgcata ttcgcaatga tctaaaacat tttgtactaa gaatgctaca
    13801 tattgttcct gtacttctaa actttcttct tgatgagtga aagccatttc tggttcgatc
    13861 atccagaatt cgatcaaatg acgtcgtgtt tttgattttt cagcacggaa agtcggaccg
    13921 aatgaaaaga cttttccgaa agccatagca gcagcttcca tgtataattg gccactttga
    13981 gataaataag ctttttgatc aaagtaattt gtttcgaata gatccgtagt gccttctggt
    14041 gcagaaccag tcaagatcgg cggatcaatt ttgacaaaat gatgttgatt aaagaattca
    14101 tacgttgcac gaatgatttc atttctgatc tgcataatcg catgttgtct tgaagaacgc
    14161 agccataaat gacgatgatc catcaagaag tctgttccgt gttcttttgg tgtgatcgga
    14221 taatcgtggc tctcgcttac cacttccaca tttgtaattc cgatttcata accaaatttt
    14281 gaacgactgt cttcacggat ttctccagtt actaacacgg atgtttcttg gtgtagattt
    14341 ttagctgttt ggaaaacttc ttccgacact tcgcttttta caactacacc ttggaaaaag
    14401 gctgttccgt ctcttaattg taaaaatgcg atttttccgc ttgatcgctt atttgcgacc
    14461 caagcgccga ttgttactgt ttctcccaca tggtttttcg aatcgatgat ttgaatttgt
    14521 tccacgtatg actctccttt tatattcctt gaatttcttc aggattaatt ttgactttta
    14581 ctctcaataa attgcttgat tctgcgtacc gcttcttcta acgtagcgcg atcagtagca
    14641 taactcatgc ggacattttc tggtgcccca aagccttcgc cagtcacaag cgctacccct
    14701 gtttcttcta aaagatcttc tacccattgt gtgacatttt catatttaca catgcgtagc
    14761 gtttctttta cattaggaaa aagataaaaa gctccttgcg gcttttcaag agaaacacct
    14821 ggcagttctg ccacaagcgg atataatgta ttcaggcgtt cttcaaaggc gttccgcatt
    14881 tcttctactg tatcttgctc acctttcaat gcttcaacag ctgcatattg actgactgct
    14941 gtcggattac tggttgactg ggaagcaaca gcaatcattc cattgatgat ctcagaattc
    15001 cccaccgcat aaccaatgcg ccagcctgtc atcgcatatg ttttagacac gccattgatg
    15061 atgatggtct gatttttgat tgcttctgaa atcgttgcaa ttggagtaaa ctcattgcca
    15121 ttataaacta aacgaccata aatatcatca gcaactatca aaatatcatt ttttactgcc
    15181 cattcaccga ttgcctgaag ttcattcttg ctataaatca ttccagtcgg attcgatgga
    15241 gaattgatga ttacggcttt tgttttttct gaacgtgctt gttctagctg ttcaacagta
    15301 actttccagc tattggattc ttcccctttc acaaagacag gaagtccttc tgccagtttt
    15361 acttgctcac cgtaactgac ccagtaaggc acaggaatga tgacttcatc ttgcgggtca
    15421 aggatcgttt ggaaaagggt atacaaagca aatttcgctc cgtctgttac aactgtttgt
    15481 gaaggttcat agacaagtcc atagtttttc ttcagataat caacgattgc ctgtcgaagc
    15541 tctgggattc ctgctgttgg tgtataatag ctagctttcc cattgcggat tgcttcgatt
    15601 gctgcttctt ggatgttttc tggtgtcgca aaatccggtt ctcccacagt caaactcagc
    15661 acatctctgc cttttgcttt taatgccttg gcctttgccg cagctgccaa agtgacagac
    15721 ggttctaatc gttttgttct ttttgataac tccatcccat tcattccttt accttttaaa
    15781 ttcccttgat tgtcttgact tcatctccag attcaaagcc aatcaggtaa taattcagtt
    15841 tcccatttgt ttcttttcct actacttccc acacaggctg atcatcatac atccctaaag
    15901 cagctttttc gatttggatt tcaggatggg ccgcagcaat tgtctgtttt gcttcgtttt
    15961 cagtcagtcc ctttgtttga tccaatactt ttactttttc accagattta ggaatgataa
    16021 cggcgatttc ttttccttta tcatttgtac ctgtcagtga aaagtatgtc ttctttcgag
    16081 taaaccaata aaaatgatcg gtttcctcaa gatttgcata tttctttgcg atttctactg
    16141 cttctttctt cgcctgcacc gccggacgac tggaacgcaa gtaaaaaatc gagctgatca
    16201 cgatgaccgc taataaaaat acgatcaagc caagtaacac gcgattaatc gttttttcct
    16261 ttgtctgttt tttcttcaag ggtcgtcgct cctttatctt cattcctttt cattatagca
    16321 gattttaatt atgaaaaaag acagctcctc taacttcctt cttcattttt ctttaagaat
    16381 tcatggatat cctgatagat tttctccata gctagctctt tgatcggtac ttttttcggt
    16441 aatgtatgga tgatccgtgc gccatatttt gcagtgacta gtcttcgatc caaaataagc
    16501 aatacgccac gatctgtctc cgtccttatc aagcgaccta atgcttggcg taacttcaaa
    16561 gctgctttag gtacggattc ctggtaaaaa ggattgatcc cctctgattc taaataagcg
    16621 ttcctagctt tgaccatcgg gcgaagcgga ttatcgaagg gtaaacgtgt gactacaacg
    16681 atctgcaaag catctccagg caaatctaca ccttcccaaa agctgtcagc gccaaacaat
    16741 acgctttttt ctgacaaaat gaagcgtttc aaaagcttct cccggcttcc accaaaccct
    16801 tgagctagta tttctcgtcc tttttctagc atagacagat gcattttctg atagaccttc
    16861 tgcaaaacat catgagaagt gaataacaca agtattggcc gatcttcttg ttcgatcaga
    16921 cctgtaagtg ctgtctctaa ataatcgatg tatgcttgat tgctgacttg atggacggca
    16981 ggtgcctctt ttggcacata gatccttgcc tgtttctcat aatcataagg agaggcaatc
    17041 actttaagag gtgctgcttc aatgccaagc cgcttagaga gatagtgtcg attagggccg
    17101 atcttcagcg ttcctccaat ataaagaata cgatcatatc gaggatacca aacagtcgac
    17161 ggcaacatag ccgcttgaaa atcatggaga tgaaaaatca tctgctgcgc tgtgttccca
    17221 ggaacgaacc aatggatcaa atgatctcgc cagtcttcca gccattgatc catcagcaag
    17281 tactgcttgt ctaattgatc aaataagcta tataaacttg ctaaatcgat ccgcatctgg
    17341 tttgtccagc tttcttggat aatctcaaaa gtcagacgca tttgtgactg tagctgctgg
    17401 atctcctgat aaaaaagctg caggtgatca atggctgtct cagattccag tggcagctga
    17461 tccaacatct cttttgtcat catgacttct tctggatact gtccgttagg ttgcttgccg
    17521 ctcactaaac tcattaatcc ttctgccata caaatctgtg cttcgcatag cgcagaaagt
    17581 tcttctcgat aaatcgataa ccatcgtaag gcttcatgtt ctttcggtaa atagctttgt
    17641 attcggtcaa acagctgatt tggttcttct aattgctgga tttgtttatg gaaatagtta
    17701 atacttaatc gtttgtcatt tactttttca gcgatttccg gcaaatgatg tacttcatcg
    17761 atcaacaaaa atggactagc tggaagcaat ggttcttttc gctgtgtttc ttgtattaaa
    17821 aacgcatgat tgacaatcaa aaaattactt tgcctgattt tcttttgcaa gaaacgaaca
    17881 aagtcttgtt cgtaaaatga ctgatttctt gctaaaaatc caatacctct gtgcgcgata
    17941 tctgcaaaga atgaatggtt caaatttgtt aaatgtaatt catccaaatc accggtcttc
    18001 gtttgcgtca gccaaactaa aaccgccatt tgatacaaag catattgttt ttgttctggc
    18061 ggttccacaa gtgtgccttt aaaacgctgt aaatcaatat agtggcgata gcttttgata
    18121 attacaggtt gtatgggctg atctagcaat tgattcagca atggaatgtc tttttctatg
    18181 atctgctgtt gcaaaactag cgaaacggta ctgatgacag cgggtttttc aggtgtagcc
    18241 aaataactca atggcagcag ataaccgatt gttttaccca ttcctgtagc tgcttcgatc
    18301 atcaaatctt ttgattcatc ttttgtgaaa tggtcgtaga ccgcattcat cagtctgttc
    18361 tgttcttttc gatacatcag tgttttacca aacatttttt cttttgcttg tttttttctt
    18421 ggatatgtcc gctcgccata atggacggat gtgaatagtt ccacttcttt tttctgcaaa
    18481 gctagcccat cgacgatttc taatgaggga tcaagtggct ctggtttttc tttcatttct
    18541 tcaatcacat gataaatgaa acgactcgta tccatacttg tgtgtctact taatcgcgca
    18601 atctgctcta acgtgatgat tggcaatttt ctcatccgtt cttcgatcag caaaagaagt
    18661 tgacctgtca cttcggcatc actatctgcc tgatgaggat tctcatgaat aaatccaagg
    18721 ctttctgaca aatcagctaa gcgaaagctt ggttccgtcg gcaagaaaat ttgtgcaagt
    18781 tctactgtat cgatgcctgg tatcttcaaa ctaggaagtc cgcatcgcat gagttcatgg
    18841 ttcaaaaaat tataatcaaa ataaatatta tgcgcgacaa atatggtgtc tgccaaaaga
    18901 ttgtaaatcg tttgggcgac atcttcgaaa taaggcgctt tttggacgcg ttgattcgtg
    18961 atccctgtta aatgctggat ttgttttgaa atcttccgcc ctggatgaat atcgatcgaa
    19021 aaacgtgaag tgatccgacc tgattcaatc atgacgcagc caaattggat gatccgatct
    19081 tcttttggat tcgtcccagt cgtttcgata tcaacgactg cataagttct tggtttcaaa
    19141 atatcttcct cttctcctgc ctctaatgtt cttttgaaat tatactacaa agtgcagaaa
    19201 aatactctca tcgcttttta aagaaaatag acaaaaacgc ccagacacgc aaatgtctgg
    19261 gcgtttattt tttagtatag gttaattaag ctttagtaac gtttgttgct tgaggtccgc
    19321 gttggccttc ttcaacatcg aaagttactg cttggccttc ttctaaagtt ttgaatccgt
    19381 cgccttggat agctgagaaa tgaacgaata catcgtttcc gttttctgca gtgatgaatc
    19441 caaatccttt ttctgagtta aaccatttta ctgtacctgt ttccataata aaaatcctcc
    19501 ttgtgtatca acacatattt tgcaattact tgaatggtgt atatctggaa gatgtttatt
    19561 tgaaacaagc taccacagat taccgaacaa aaactactcc tatagtatat cataccgttt
    19621 acaaaaaagc tagatttttt cgactttttt tattaaaaaa agttttctca gcgattacat
    19681 aaagtgaaaa accgaacttt ttttaaaata aacgacatat tgttcagttg gttttttttg
    19741 ctctgatgtt cttttttaaa ctaaaaaaat tattctttct gactacttat cggttctgtt
    19801 tcaacggtcg aggctgggga agattcttta gtaggtctga tgttctcatg gtatttctga
    19861 tagcctatga cagttaccag aagaacaagg caaaccaata cgatcaacga gattagtttt
    19921 tcttttttgc tcatatctat acctcataaa taacaggatg atgtccatca tatttctgag
    19981 tatgagtaaa agcaaaagct gcagctgtag aatgtaagaa atgccagcaa ctttcataat
    20041 cacaggtcgg acagtaccaa aagtaaccaa atcttggctg caaagaccgt tcttctgttt
    20101 caggaatcgc agaatcaaga tctggtgtct gtacataaac atttttgtac agacgtgtgc
    20161 ctgtaatagg agaccgctgt gtttcttcag caaaaactgg ctgacttgtt aaacttaggg
    20221 atagaaacag caaacaccat aacagtcttt ttttcataaa gacctcctta tcgataagtt
    20281 tttcccaatt aaaatcatat ctcaagaacg cccgttattc acattttgtt cataaatgat
    20341 gttttttgta tcataatcgt caaaaagagg tcgtgaccac gtcacaacct cttttttaaa
    20401 cggtgttcca gaagtagctt cttcggaaat aagccgaaat ttcacaaaaa tttgagaaat
    20461 aatttttgtc aatctcttct tatttcttga agctgaccac ttctgtcaca acctcttcct
    20521 taaacggtat tcaaaagctt gcatctgcgg taataagccc accaaacaaa aaatatgaag
    20581 agctattttt gcttgctgtt cttattactt gatgcagaac agctttttca caacctctca
    20641 tacacggtgt ttaatcagct gaccttcggt attagctcaa aaaacggaaa aatatgtgaa
    20701 actatttttc cgtttgtttc tctaatactc aggtcaaaac actgatttca caacctcttt
    20761 taataacgaa gaatcgctgt cagactcttt tcatctggcg catctttttg atccaaaata
    20821 aacactttcc cgccattaat gatcacatca tctgctaatg cattcaacac ttgacgccga
    20881 tcatattctg tttcaggatc ttcaccgaaa ccatcagcta agtttgacgt agcgataaat
    20941 agatgcgaca cttttccttc tttcgcagct ggaacgatat caactaactg atcgatgaat
    21001 ttcttatcta aaagtttatt gtattctttt gattcttgag ctgcgagttc acttgacagc
    21061 ttcttcgccc cttcttcgat atctctaaag gatagctgcg caggagaagc agaaatcgca
    21121 acgtctgcac aatagtaagg atttttagct atttttttga acatcgtctg attttctggt
    21181 aatgcaaata aataaatcgg ccattgttct ggattttcga aagaatcctt caagtacgta
    21241 tcaactgctt ggtaatagtt gacccaatcg atctctacct cttcatcttt tggatttacg
    21301 ccatggaaag ttactccatc tcgggctccg cctcctccat tagaagagaa gttcaaaccg
    21361 ccacctgtca gttcagatcc caatgcagta acgacatcaa ctggtgcccc ttctggtaga
    21421 gatacttctt ttacttgttt gttgctgacc tcatacaatt tcatggagtc gcggttcaat
    21481 cccaataaat aataagaata gttgaactgc ccatttttga taatagccag taaataagga
    21541 agatcactta catagtattg atcgtctacc gggatactca aacgatggat ataggtttgg
    21601 tcagcagtta taatgaccgc tacactcgta gttgcactac gccagaacga aggatctcct
    21661 aacaaatttt caattttttc ttggaacggg gaccagtcat gctcggaata ttttttttca
    21721 aaacgtttct ttgcttcttt tgcaaaattt ttgaatttga tttgatcttt ttccacatct
    21781 tgatgggcga catgcgtatt cagcatgatc gtgacgaacg gtcctttagc gccttctgaa
    21841 gtcaattgtg acaatagttc tttatccttt tttgccataa acgtacccct cctaaaaaaa
    21901 tcattccttt gtgtctatct aaagtctacc acaacactat ttttccatac aataaaacgt
    21961 atctaaaaaa ataaaacggt ttctttagtt gggtattttg caattttttt aagttatctt
    22021 cataatttcc tcaattattt aggcacagtc ttcaactatt cttcatgaaa ggctgttaga
    22081 ctaagaaaaa gaataaaaga ggtggacctt atgcatttga ttatgatttt tagtttatta
    22141 agtatcatca gcttatttgc tttcagcgct tcccgcttat tagaggcgga aacacagcct
    22201 gttcctgtaa aagtacggaa aaatgaccgc taaccttttc ataacgcgcg ttcttatcct
    22261 aaagtttttt tcagaaacat tgaaactctc ttccctctct gataaaattt taatttgtag
    22321 cgaaacaaat taaatacaag gagatcggat atgtccataa aaaaaacacg tctagtccta
    22381 ttattggcta gtctcattct ttgccttgct tcttttctac cagctgttgc tgtgcaagct
    22441 gaagatactt tcaaagtaaa tgcaaaagca gcctttgctg tagatgcgca aagcggtaag
    22501 attctttatg atcaagatgg agaaaaaacc atggggatcg cttcaatcac aaaaatcatc
    22561 ggtctttaca tcgtccttga tcaagtaaaa gaagggaaac tatcatggga tgataaagtt
    22621 tcgatttcag attatgcaga aaatttaagt gtcaccccag atttatcaaa tgttcctttg
    22681 cataaagaaa atacctacac tgttaaagaa ttattcgact ctgcaatcat ccagtcagcc
    22741 aacgcttcaa tggttgcctt ggcagaaaaa attgctggca gcgaagcaaa attcactgaa
    22801 cgaatgaaag aacaattgaa agattgggga atcaaagatg caacgatcgt taatgcatca
    22861 ggactgaata actcttatct tggcgaaaac cgaccagaag gtactggaga aaacgacgaa
    22921 aatcaaatgt ctgctcaaga tgtggctatc gttgcccgtc atttgatctt ggattttcca
    22981 gaaatactgg atgtatctag cactacgaca caaatgtttg gcgaaaacac gcaatcacca
    23041 gtggaaatgg tcaactggaa ctggatgctc ccaggattcg tgaattataa agaaggcgtg
    23101 gacggattaa aaactggtac gactgagctt gcaggtgcct gtttcgtcgg tacgatcact
    23161 aaaaacgatc aacggatcat cactgtcgta ttgagtgcag acggccatgc ggaaaaccca
    23221 agtgcccgtt tcaatgaaac agcccgctta atggattatt gctacgacaa ttggtcagaa
    23281 aaagagcttg gaaaagccaa tgcaagtatc cctagtctaa aaaccattga tgtaaaagac
    23341 ggaaaagaat caacagtgcc cgttgtgctt aaaagtcctg taaaagtatg ggtacgaaac
    23401 gatatggata ctggaaaatt aacaatcact ccaactcttg acaaaaagca agtcactgac
    23461 aatgagatcc aagcacctat ggataaaggg acaaaaatcg gtaccgcaac gatcaccttg
    23521 gcagaggata aattaggtta tctagaagac aacaacgcgc catccacaga aatcatcacg
    23581 gataaaaccg tagaaaaagc aaatattttc gttattggct ggcgacgtgt cgcagaattt
    23641 ttcggcaact tgttttaatt gaacaaaaag aaaaaagcat ctttccgtat ggaagatgtt
    23701 tttttgcttt ttctagttta aataacagct tttttcatct attttcgtta tactgtataa
    23761 gaaaaaggag ttgaatttat gaatctaacc agagatctga tttttttggt tctctatctt
    23821 attggggtat tctccatcgt ttattggcga aaacagaaaa aggatccttc cttgttcttt
    23881 tacagcagta cgtggacatt tgcggtaatc ttgacttatt ttgtcgtgtt ggaaattttt
    23941 tattcgacct tttatttttt gattccctta gtgtttttca gtatctttgc cttttcctat
    24001 ttttcagaaa agcgaaggct gctgaatggt cttttattca atgttttcct cattagtttc
    24061 ggtatctact tgtttgtctt gctatacgaa acacaaaata tttttcttgg cggactgatt
    24121 gccttgatca cgatcccgtt actgcttgtc tttctattcg gcatttatgg attgatcgtt
    24181 tttctttttt ggaacggtgt cacagtttta cgtagagagt cacattcatt agctaatctt
    24241 ttaacgttga tactagccat ttttcttaca ttgtttctta tttttgactt tttcttgtta
    24301 aaatatttgc cgcaatggat aaatgctttg tttttctgca ttccattgat cttgatctat
    24361 ctatttatcg tattctacaa ctttttgact gtctcattct tgtatcagtt caaccgccct
    24421 cgatacaatc aagacttcat cgttgtgtta ggcgctgggt tgatcaatgg agaaacagtt
    24481 tctcctcttc ttgccaagcg aatcaataag gcgattgctt tttattgggc acaaagccgt
    24541 gcaacattaa atccgcctat cttattaatg tcgggtggac agggagcaga cgaaaatgta
    24601 ccagaagcaa ttgcgatgaa acaatatgcc atggaacaag gaattcctga aagagatatt
    24661 cttgtcgaaa ccaattcgac aaccactttg gagaatatgc gctattcaaa ggaaatcatg
    24721 gatcagcaaa tgaaaggtcc ttatcgcgcg atcttcagtt ctaacaatta ccacattttc
    24781 agagctggtc tctatgcacg acaagcgaaa ctgaaggcaa atggtattgg ggcaaaaaca
    24841 gctttctatt acttgcctaa cgcgttttta agagaataca tcgccatctt gatgatgaac
    24901 aaaaaaagac atatgatcat ttgcggattg cttttcgcag gttccgcatt cttatcactg
    24961 atcactttac ttttctaaaa aacaaggtgt gacaaatata tgtcacacct tgtttttttc
    25021 ttttattctc ttgacgattg gcaagaatag tattcctttt ttgacggcta cttgctgtgc
    25081 agaataaata ccgctgtttc ctgaacacat aaagctgatc aagcagatca taaagaagta
    25141 aacagcagct tgtgaaccaa ataattcgat tcccatcaca aaacaggcaa ttggtgtatt
    25201 tgtcgcacca gaaaataccc cgataaaacc taatccagca agaaaaggaa cagaaacatg
    25261 gagcaaaggc gctagtgctg cgccaagtgt tgcaccaatc tcaaacagtg gtgtcacttc
    25321 tcccccttgg taccccgcac ctaaagacaa gactgtgaag aataatttcc caataaaatc
    25381 ataagcatat gcctgtccat taaatgattc ctgcagtaac ggaagactca acccaaggta
    25441 acgttgtgtt tgcaaaatca acgctgcggc tacaactact gctccaccta tcgtatttcg
    25501 ccaaacagga tgaggaatcc attgcgcata ccgcgctttt aaaaagacga tcgaacggct
    25561 gaatacccaa ccaatcaaac caaaagcaat cccagcaaca aaaactttga agaacagcaa
    25621 catactccat tcaggaatca cacccatttg gtaatgtaga tgagaaacac catagctttc
    25681 tgtcatgaaa tttgcaaaca gtgcagcaaa gaagctaggg aagatcgctt ctgttcggac
    25741 tttcccgatt gccaacactt ctaatccaaa taatgttcca gctaaaggtg tgccaaatac
    25801 agaactaaaa cctgcactga ttccactgat aatcaagatt tcccgttctg ctttatccaa
    25861 tcggaacaaa cgtgctgtat tatctgctaa cgctcccccc atttggactg ctgttccttc
    25921 acggccaaca gatcccccaa ataaatgggt agtgatggtt ccaaacaagg tcaatggaat
    25981 gagccgcaaa gggatctttt cttctcctcc attcccttga tcgatcacta agttattccc
    26041 acgactagaa agaccgccat gatacgcata aagataagca aaaagcgcgc cgctgattgg
    26101 caatagataa agtagccaag gatgtgctag tcggatatct gtcacgaacg tcaggctatt
    26161 taagaaaaaa gcagacaagc tccccatgaa tactcccaga atcgctgtga tcaccaacca
    26221 cttcagcatg tacatcaaaa tacgcactgg actcggtaat tgtttttcca taaaaaattc
    26281 ctcctcaata aaaaaacgcc tactaaagaa aggggctgtc cccagacttt agtaggcgtc
    26341 attagctatc tttcgttagc atttaaaggc gaacaccatc acctattcac ttccattaaa
    26401 agatagcata tttttctgta aaaaacaata aaattatcgt tctttcttta cacgttcagc
    26461 aaattcatag aaaggagcca atttcgtcaa ctgttgatta cattggtcac tatcatgaca
    26521 aatataattc ccctttttcg tatacgtgcc atcagaacct gctttcgttg tagaaagaaa
    26581 aagcgaaaca ttcgatgttt tctgacagat tgcacagatt cccttattta tcgttggtga
    26641 taaagtaccg ctgatccctt ttaatttttc atcttcgtaa tagaccatga attttttttg
    26701 cgtccctgga tcattccaac cgatgtacgt atgtgcttgc aagtcgattt cattccaagc
    26761 tggttgtttg agttttttca cttttcggaa taatttatcg atttgtggtt tgctcggctg
    26821 cataaacggc tggacgattt gcttcagctc ctccaatgct cgttctgctt gcgtttttgt
    26881 cagttttaca tctaaaactg tcgttaaaaa cgtatcgatt tctggtggtt cgtaacctaa
    26941 tacatcgcga atcttttcag ctgctagagc ctgaaccgtt tgtaccgttt ttgggtcatt
    27001 gacagatgag tacgcattta ataactgatc aacttctctt tttataaaaa aatattgata
    27061 tggtttcatt gtttgttcca tgattttaaa gtcctttctt ctaaccaaag tgcatacttt
    27121 gtagaaaaaa gtgatcttct gcaaagtatg tgttacctga agatcccgga ctcttttaaa
    27181 taagatacgt tttgcatctt atcatcaccc cctttaatgt ttattcttct atgtacatga
    27241 ttcattcgat aaataaaagt aaaccgtatc ttgaccagat agtcaactgc aaacagaaaa
    27301 aggactgtga caaaagtcgt gtcaaagtcc ctttctacaa acaaacggtg ttccagaagt
    27361 agcttcttcg gaaataagcc ggaatttcac aaaaatttga gaagcaattt tcgtaaattc
    27421 cttcttattt cttgaagctg accacttctg tcacaacctc aatatggtct attattggtt
    27481 ttacctgtta aattgaagat tcttttccaa agtaacgttg ccatctctta cgcatacttg
    27541 ctgacatagg ctgagcggct tctttgactg cgcagtattt gtctacgaat gttacgatat
    27601 atccttcttt gtacttaggc ggtgcaatcg ttgcgcccca catgtgcttc aaaatgatat
    27661 ctcgctcaag atccgacaat ttggtgatct tttctgcatt ctttacagcg attcttggat
    27721 ggatatacgc atgtgtacct tcatcgaatt tcgtcgtacg ccaatcatag tagaacagat
    27781 catgcaaaag tccagcacgc gctgttgctt tagcattgcc accccatttt tttgcgagca
    27841 gataactata gtaagaaaca ctgatggaat gctccaaacg agtggaatga acatgctgtg
    27901 tgtaattcgc taattttttc actgcttctg tttctaaaag atcttgtaca taagacatat
    27961 attcttcgtc ttcacgccat ttttctgtca taattatcga tctgccacct ttttgaattt
    28021 cattttcttc tgaaattgat ctaagtatac caccagtgtt cggattattc tagtcgctct
    28081 agataaaata gctaaagctt aatagttcct taatcataaa gaaaaatgat aaagaacgat
    28141 ccctgctgcg actccgacat tcaatgattc cgcatttcct ttcattggga tatatacgtt
    28201 ctgatcagtc aaagacaaga tttcctgact taccccctga ccttcgtttc ccatgattat
    28261 agcgaaatcc tctgtttttt ctactttgtc taatgcatgt gcttcttcat ttaattctgt
    28321 accgtacacc gtaaaccctt tgcctttcat tacagggatt acatctgcca aatctttttg
    28381 taacacaggc aaatgataat tgcttccctg catgcttcgc agcacctttg tactataaat
    28441 atctgccgtt cctttaccta ataaaacacc agccatacca aacgcatctg ccgtacggat
    28501 catcgttccc acatttccag gatcctgtac attatctagt aaaagccagc ctcctgaaaa
    28561 atctggcgta tcttcagatg ttaacgtcat caccgctaag atcccttgcg gtgtaggtag
    28621 atctgacata gcggtcatga cctcatctga aactagaaaa gtagaaatct ctttgtttac
    28681 agccagccag tctccccatt ctttcatacc tctctgtgtc acaaaaagtt cttttatttc
    28741 tgcatcagac gacgcagctt cttcgatcag atggaaccct tccaaaagat attctgcctt
    28801 ttcttctctg tatttctttt tatgtagttt ttttaattct ttgattcttg gattttttgc
    28861 tgattggatc tctttcacat tcctcacctc aactgattat atcatggaat aggtgcttga
    28921 gcttgtttca tcctaaaaaa atcggtatca ttgatttata aaacaggaaa gaaaggtgac
    28981 gaacatgcgc aaagttaaaa tgaatgtcca aggacgtgtc cagggcgtgg gatttcgcta
    29041 tatgaccaag atggttgctg atcagttagg cgtgaccgga acggtaaaaa acgaagacga
    29101 cggctcagtc acaatcgaag caatcggaaa tgacgacatc atccaaaaat ttatcgaaga
    29161 agtcaagaag tctccgagcc caagtggacg agtgcagtat gtggatgtcc aagaagatcc
    29221 gatgattgag gaacgaaaga aatttgatgt ggtgggataa ggttgtgaaa aggtcgctta
    29281 gttttgagta ttaaggaaaa ttttgtgaaa atggctttcc acatttttgc ataaatttga
    29341 cttaataccg agaaactgac ttttgaacac cgtcgatcag gttgtttttg aggcgctttg
    29401 cctcaagtat taaagatagg tagtaaaaaa gctgatctat aacttgcaat aaatttgctt
    29461 accccatatt ttccagacag aacaaaaaag tttttagttt tttatataag aaagaaacac
    29521 ttggaatcac tcttttcttt ccaagtattt ctttcttgat tttttgtctt ttttcaaaat
    29581 ttttcgctac gaaaaagaaa gaatatttat atgaaatttc tatgaagttg attgaattcc
    29641 atgcgctttt ttagtatagt taagtttgtg taaaaattat agaagaggaa gtattctatg
    29701 aataaatgga aaaactggtt attgggatcc ggacttgtca gtatcctgct ctttttatct
    29761 ggctgtgtgc ggatggattc aaacggaaac cctgacactt caggaatcgt ttatcgagta
    29821 ctcgtccatc ctatgggcca agcgattaca tatctagttg agaatttcaa ttggtcttac
    29881 ggctgggcag ttattgcaat gactgtgatc gttcgtatca tcatcttgcc actaggtatc
    29941 agtcaatcga aaaaaacaat gatccaatct gaaaaaatgc aagcgttaaa accacaagtt
    30001 gaagcagcac aacaaaagct aaaagctgca acaacacgtg aagaacaaat ggcagcacaa
    30061 gcagaaatgc agcaagtata tcgcgaaaac ggattgagta tgaccggcgg aatcggctgt
    30121 ctgcctctat tgatccaaat gccgatcttc tctgccttgt attttacggc tcgctacaca
    30181 gaaggtatcc gtgaatcatc tttttacggc atcgatctag gctcaccaag tatggtgctt
    30241 gtggccattg caggggtcgc ttatctgctt caaggatata tttcaacaat cggtattcct
    30301 gaagaacaga aaaagacgat gcgtacgatg ctgatcgtct ctcctgctat gatcgtcttc
    30361 atgtcgatca gtgcgccagc cggcgttaca ctttactggg tagtcggtgg tgtgttcagc
    30421 tgtctgcaaa cattcatcac aaacgttatg atgaaaccac gtttgaaagc gcaagtggca
    30481 gaagagttga aacaaaaccc gccaaaacag gtcgtcactc caagaaaaga cgtgacagaa
    30541 tcagcaaagc cagctgacaa caaacaagca acaaaacaaa tcaaacaacc aaaaaacagt
    30601 acaaataaca aaggccgcaa cgcaggaaag cagcagaagc ggaagtagat agtaaataag
    30661 agtgtaataa aaatgcatta acagttttag caattaaaaa tatcgaccaa gatttttgaa
    30721 aaagaaatct ggtcgatatt tttatttaag tgaatgtata atttgaatca tcgattgatc
    30781 gctatctaat tgcagcagca tctttttatg aagaagcaac tttttcttat ctatcaacgt
    30841 agacaggtgt tgctgtttct tttaatagtg tacttaattc cttaatattt tgttttcctt
    30901 cttctaacat ccaactactc gctttttctt cgccttcggt aacaaaaggt gccactccct
    30961 tcgcccatgt tgctcgccca cataagacac cattgaatgt cgaacctgat tgttttgcaa
    31021 aacgtaatgt atcttgaaat agcgtagcat tgactcccgc acttaaaaaa ataaacggtt
    31081 gttcagtcac tttcgattgt tcatagaaat acgcggatgc ctctgcttga ctataacaag
    31141 tctcttgccc atatccttcc acaaatctca tattcactgg cacttctact ttcaatacat
    31201 ccacttgata acgttctttt gaaaattctc gcatggcttc aataacttta tggggtttta
    31261 ctttcgcata ggcaagagag gacggatcgc caatagttgc atcataagaa aggatctcta
    31321 aaaagaaagg tatgccttct gcttcgcatt ctgaaccaat ccgttctata actatttgtt
    31381 tttgcacatt aatctctgct ggttcatcca cgtcatagta caataaaaat ttacaagcat
    31441 ccgcaccagc ttcttttaac cttttcaccg accaaatatt caataaatca ggtaatcttc
    31501 ccggcatttt cgtatcatag ccggtttttt cataagctag cagcaagcca cattctttct
    31561 ctcgaagcgc tgctgcaggc aggccgtatt ctggatcaag taaaatagct gaggcatagg
    31621 gagtcaggta ttgagaaacc atctgtttaa attggatgat gtcttctgat gtagcttctt
    31681 tatattggtt gatcattttc ttcaaagcac cacgctggtc gattgctaac gcgctaataa
    31741 ttccagcttc atccgtcaat cgcttcaaac gttcctgctt ttctatactc atcttcttca
    31801 tagatcttca cctatttctt tagttaatat tgtggctatt tctgtttttg attttgcttt
    31861 tctcaactgt tctgtaacct cttttcgcat caatgatcgt gcaacgagag acaataattt
    31921 caaatgagtc gttcctgctt ctgaatctgg aataaataac gcaaaaataa aatcaactga
    31981 ctgtctatct aaactgttcc attcaattcc tttgttcagt gtgacgataa tcatactagg
    32041 ttcgttgatt gtttgagact tcgcatgagg gatagcaaaa cctgacatta ttcctgtagt
    32101 accttctttt tctctttcca gaagtttttg atatacttct ttttcgtcat gagcgattcc
    32161 taaacagaat gtttgctttg ctaaaaactt aaatgcttct tcttgactat ctaatggctg
    32221 ttgtaaaaaa atgttctctt catgaatgat tgtcatgata agcctcctgc tcttccttct
    32281 tcgataactg tacgatttgc tgctttatta tccatcttct tgtcttcatc agttactctt
    32341 ttcttttgga ttaatcctag tatcactcca ccaacgatcg aaccaataag aatcgctgta
    32401 acccattgga tttttcctgt tactacaggt aatactaaaa aaccgccatg tggtgctgga
    32461 acttggacgc caaacaaata agtcaagaca gcagcaattg atgagcctaa catcatcgtg
    32521 ggtaacactc ggatcgggtc tttcgcagca aacggaatag ctccttccgt aatatgagtt
    32581 gatcctaaaa taaaattaac caaacctgca ttacgatcat tggtatcaaa atatttacca
    32641 aacaataaag tagcaaaacc agtaatcaac ggtggtgcaa tacaagctgc tgacacacca
    32701 gccataaaag tcgtgtttcc ttgtgccaaa agagctgttc ctgttacata tgccgcctta
    32761 ttaatcggtc ctcccatatc aaacgcacac atgcaaccaa caatcacgcc aagaacaagt
    32821 ggattcgaat gttcaaatcc agctaaaaag ctcatcattc cttcatttat agccttcatt
    32881 ggacctgcca gcaaagacat cacgatgcca ataaatgcta caccaataac tggatataag
    32941 aagattgcct tcaagccatc tagttgttta ggtaaaattg tcagtagctt ttgcaaaaat
    33001 aagataaaat aacctgctaa gaacccagct aaaatacctc ctaaaaatcc agtaccgcca
    33061 ttcatgacca cgattccacc aacaaatcca acgactaacc ctggacgttt cgcgatccct
    33121 tctgcaatat aagctgctaa aactggaacc atcattccca ttgctgcatc gccaaccgtt
    33181 tttaacatcg ccgctgtagc attgtattgt gcatgatctg gatcaaaaga atagattccc
    33241 caaacggcaa atgaaatagc aatcaatact ccgccagcta ccacgaaagg caacatatga
    33301 gagacacaat tcatcaaatt tttatagatg ctacgaccaa aattagcacc actcatcact
    33361 tctggttcta aattatcaac agcttcatta tctgctaaga cagtaccttt tcctgccaat
    33421 gcttcgtcaa tcagccgttg tgcatccttg attcctgtac tgacagaaac atcaatgact
    33481 cgttttcccg caaatctttc tgaatggaca tctttgtctg cggcaataat gacagcatct
    33541 gcctgttgat ttcttcagcc gttaattcat tttcgatccc aatttgtcca tgggtctcta
    33601 ctttgatcgt gatgcctttt ttcctagctg cttgttctaa tgcctcttgc gccatgtagg
    33661 tatgcgcaat tcctgtcgga caaccggttg ctgcaattag ttgatatttt cccatctttc
    33721 gaacctctct tccctgattt tgatttgttt acttaattcc tccacatcta aaaaatctgt
    33781 taatcctttg cgaaaagcgg ttgagctgcc tgctgctatg cttttacgta acgtttcatc
    33841 aagtggtcgt cgattcatgt atcctgctaa aaaagcgcct aacatggtat cacctgcaca
    33901 tgctgtattg acaacttttc cttttggcga gtttcctcga aacaccctgt ctttcgtaaa
    33961 aagaatcgct cctttctcac cgagggataa caaaacattt tctgcaccta actctactag
    34021 tcgttgtcca taaacaaagt aatcttcatc tgtaaccatt tttcgtccga accaagaaga
    34081 aagttcttcc tcgtttggtt tcagcaaaaa cggtcgatag ggtaaacaat ccatgacttc
    34141 ttgatcacta ctatcaataa tcaaatgaat ccccttttcc tgacaaatcc gactgatttc
    34201 tattaaaacc tttggagaca gccctcgtgg taaactccca gaaacacaaa gataatcttc
    34261 tgcttgtaat gctcttattt gatttaaaaa attatggaca gctgtctgcg gtatttcagg
    34321 cccttgattc actaatttgt attcttctcc cgtttgattg acttgtgtaa atacattgat
    34381 acgcgtcata ccaggcactt caataaactc tgtttggatt tgtttctgct gtaaatagtc
    34441 ttctatatac tttcctgtga acccagcaga aaaacccaat gccgtacttg ggaaatctag
    34501 catttttaat actagtgaca cattcacccc ttttccgttt gcctgaatgt catcttcttt
    34561 tgtgcggttt accataaaag gatgcatctc ctctgtttca ataaatagat caattgccaa
    34621 attcatcgtg catgtgtaga tagacataac caacgacctc cttgactcta ttatgaaata
    34681 cgcgaaagag aaaatgtttt cttaatcgtc ccaacacaaa gaaaaccttt acatttataa
    34741 actcgtcgtg ctatttttta actaactttt ggtgaaagaa ggaaagaata tggatcacaa
    34801 attaagtgaa acagaacagt acctctggaa ctttatcgaa caccacatcc tagagatccc
    34861 taactactcc atcgtgaaac taagtgaaca agcgaatgtc tcaacagcca ccattgttcg
    34921 gacaatgaaa aagaaaggct atgaagggtt tacttcgttt aagcatcatc taaaagaagg
    34981 agaaaacaag aacatcaatt tttctttctt agataaagta gacaaaggta tccgccgagc
    35041 cattctaaaa aatgaacaag aagtggtacg tacgatcaat atgttggaaa tcggaaacat
    35101 tgaggatgcg atacaaagaa tcaaatttgc tgaccgggtt tttgtctttg cccgaggatt
    35161 ctcagaaatg attggccaag aaatgctggt aaaacttcaa ttaacgggaa aaaattgtca
    35221 aatgcatact gatccagaaa ttatcaaaag catcagtcgg aaactgacta agaaagacag
    35281 tgttattttt gtttctttga acggcgagac aaaagaactc gtcaccgccg caaagaattg
    35341 ctatgatgca gagattggtt caattctagt tacagccaat cattcctcta cactcaaaga
    35401 ttattgcgag ataaatctcg taggtttcaa atcagaaggt tcgtatttcc ctaattatga
    35461 agtacggtca cgcttgcctc tccagattat cgcgagaatt ctgcttgacg cctatgtatt
    35521 gcgtatgggg gagaattgag aagcagttta ttgtggttgg ttacagttta aaacatcaca
    35581 tttttttatt ctttatattg tagggactca cggaaacttt ttatgtataa ggttattcac
    35641 aatccacaag gttactttaa gtaacaaaaa aataagtgaa aatacttaaa actaaaaaat
    35701 atctttttaa tcaataaaaa aattgacata tttattaata ataagctatt ctgttataga
    35761 agaaaaaatc atttgttatt aatagtaaca aaaaggagta tatcatgaaa aagttatctc
    35821 aaaaacgttt agctcaaatc attattgatt ctagaaaatc tctaaaaatg acacaacaac
    35881 aacttgcagt agctactggt atcaaccgcg ccttaattag tcgattagaa tctctcgatt
    35941 ttatcccttc aatacaacaa ttagaatcat tagccgaagt tctaaatttt gaaccaacag
    36001 atctatttat aaatgaatca aataaatcaa acagaacaaa acatcagtcg aagaatattg
    36061 ctgtagctgg tactggttat gtaggtcttt ccattgctat tcttcttgct cagcacaatc
    36121 aggtaacagc agtagacatt attcctgaaa aagtaaaaca aatcaataat aagaaatcgc
    36181 caatacaaga cgattatatt gaaaaatatc tagctgaaaa aaatcttaat ttaattgcaa
    36241 cgacagatgg agcaaccgct tataaaaaag cggattttgt tgtcattgct gccccaacaa
    36301 attatgatag taaacaaaat tattttgaca cttctgctgt agaatcagta attgaattgg
    36361 tattagcagt caatccaaaa gcaataatgg ttatcaaatc gacggtacct gtaggctata
    36421 ccgaaagcat tcgtgaaaaa tacaatacta aaaatattct attcagccca gaatttctca
    36481 gagaatctaa ggcattatat gacaatctat acccttcgcg aattattgtt ggcacggacc
    36541 aaaatgacaa aactttacta gaagcctctc atacttttgc agatttactc caagaaggag
    36601 caatcaaaaa agatatcgaa actcttctca tgggattcac agaagctgag gcagttaaat
    36661 tattcgctaa tacttacctt gcacttcgag tatcttactt caatgagctg gatacttatg
    36721 cagaaatgaa agaattaaat accaaagata ttatcaatgg agtatgtctc gatccaagaa
    36781 ttggcactca ttacaataat ccctcttttg gatacggtgg ctattgttta ccaaaagaca
    36841 caaagcaact tctaactaac tataacgata tacctcaaaa tatgatgagt gcaattgtcg
    36901 atagtaaccg aacaagaaaa aactttatag cagaccgcgt gcttcaaaaa actggatatt
    36961 attcttacga tgatgacaat actttcgatt tgtctctaga aaaagaagtg attattggag
    37021 tctataggct tacaatgaaa agtaattcgg ataacttccg tcaatcttct attcaaggta
    37081 ttatgaaaag aatcaaggca aagggagcca ctgtgataat ttacgagcca acacttaaag
    37141 atggtagtac attttttggt tcaaaagtaa taaatgattt agaaaaattt aaaagcataa
    37201 gtcatagtat tattgctaat cgatatgata gtattcttaa tgatgtaaaa gaaaaagtat
    37261 acactagaga tttatttcaa cgagattaat atagtgatct attttgatac tataattctt
    37321 aggctctttg tcaaatgatg ttggtgaaga gatatcctag aatgattttg accagaaaga
    37381 aaaaatttct ttctggtcat tttttatttt atgagcaatg ctttcacata tcgaatcatg
    37441 attcgcaatt taaagttata aaagcttcga aactcatagg catttcgttt taatacctcg
    37501 atatgattat tcaaacactc caaaggccca tttggtgtta gtatcaaatc ttagacaact
    37561 tttcgtagag acagaaataa attaaactta tctacgagag gatggatttt atgacccgat
    37621 acgaagaaaa tttcaaacag atgattgttg agctgaatca aactggacgt tctgttcgag
    37681 gattggcgaa agaatatggc ttatctgaag caacgattta caaatggaaa aatttatatt
    37741 taccaaatca gtccacagga ctgaccggaa aagaagcggc tgatttgaga aaagaaaatg
    37801 ctcgtttgaa agaggaactt gaaatattaa aaaaagccgc agccatattc tctcgaaaga
    37861 cctaaagtca cttgttcgat tcattgaaaa atggtgtaag gagtacactg tttctttgtt
    37921 gtgtcggtta ttagaaattc ctagaagcgt ctactatttt tataaaaata aatcgttaac
    37981 agctacagaa gtcagaaata accaattgaa aaagaagatt tcaacgatct tttttgatca
    38041 taaacagaga tatggtgcaa caaaaatcca tcaagtgttg ctaaaagaag gaatttcagt
    38101 atctcttaag catgtacaaa aactgatgaa acaattaaat ctaaggtcaa ttgtggttaa
    38161 gaaatacaga cctcaacggc ctgttcagcc ggttgtttta aaagagaaca tcttaaatca
    38221 ggacttttct actaaaacta tctgtgaaaa atgggtagct gatatcacct acattccaac
    38281 taagaaaaat ggttggtgtt acttatcttc gattatggat ttacacacga aaaagattat
    38341 tagctataca ttttctaaac gaatgactgt cgattgtgtg ttacaaacat tcaatcaagc
    38401 aaagcaacgg taccacatcc cagaaggaat gattctacac actgatttag gtagtcaata
    38461 tacagcaatc gaagtggaaa attggcttga aaacaataaa ataaggcatt cctatagtcg
    38521 caaaggaaca ccatatgata atgcaggaat tgagtccttc catgcatcat tgaaaaaaga
    38581 agaagtatac acgacgactt actcagactt cgaagaagcg aatcgatctt tatttagcta
    38641 cattgaagga ttttataatc gtaatcgaat ccatagttcg attcattact taactccaca
    38701 ggagtttgaa gatttagaaa cagagaaaat gtcttagcag tctctactaa aatatgtcca
    38761 agatattgac tcaaatccag tgcagcaata actacaaaat ccgcatcctt atacgcagcc
    38821 tctgcatcta acgtagctgt cagctttaac tctttttcct ttaggtattt ttcaatatac
    38881 tcatcctgaa tcggactaat ccttttatta atcttctcta ctttttccgg aacaatatct
    38941 actgccatta cctcatgatt ttgagataat aatgtggcaa tagaaagtcc cacatatcca
    39001 gttcctgcta ctgctatttt cataaaatat ccccactttc tactatttac tcagaacttc
    39061 tacttgtttt tttcaaataa acatatgtag ttattagcaa tttaattata tttgccaaca
    39121 atgctcctat acaaaatccc attaatccgc caagttttaa taaactaaga gaaataatta
    39181 tatacattat tgttgtaatt ccattaatcc aaatttgcca tttaatatca aaaaagcgta
    39241 ggacaaacgg agtaatcatt gatgtcaaaa cagatactac tattgttccg gaagtaatcc
    39301 agatatactg catagctgca tccacatatt tcggatacaa tatactcaat accggtctac
    39361 ttaaaattat agtcattata tatccaatac cacacacaac aattccaact atatacgtcc
    39421 atttaaaaag ggaatttgtt ttcttattaa tttttgaaag ataacttaat gctacactat
    39481 taattggtgt aattgccaag ctaacaactt tgctaaatac cgtagctgca taatatactg
    39541 aaaccatcgt tccgcccaaa agtggataca gcaatatctt atcagcgtaa tttattgccc
    39601 tagctaatac attagaaatc aataaaaatg cagagtcatt aaagacgatt ctcaatcttt
    39661 ttgtctttgt aaaaggctct tttactatcg gactagctat tactatatgt aaataactta
    39721 aaatataacc taataaatat ataatttgcc aatatccatt tttcataaaa aagatatagc
    39781 ctataccata tccagccaca agacataaat tattgactaa aattgctata taatccagtt
    39841 ttaatctaaa tgccacaata tggtattctc taccaagcca taagatgcct actgctataa
    39901 gtaataatat accggttata tctttggtac ctaaataata aattgatacc gttaccatta
    39961 tcaacaaatt aattgcctga aatattgtta ataaaatttg aaaatcgccc tgctcattat
    40021 cctttttata agattcctca tgtagcaacc ttacattatt taatacattt ccaattgtag
    40081 atggaactac atttaaaacc gctaatattg taaccatcaa tccataagca tttccatcca
    40141 tataatttga taatgatgga agtatcaaca attgcaatac caccgtagga attgatgttg
    40201 caacaatatt aaggatcata tcaaaaaaaa tttttttctt catatcattc ttcccttttc
    40261 aaatatttac ttggtatcct gaataattca tactttgact tcaaaccgtc tgaaactgcc
    40321 taacggcagt cttcattttc tttttcattt tcacctgtta agtgatgcaa aaagaacccc
    40381 attctgatat ggtaaaggtg tcgaaaccaa ccataagaaa ggagttcttc tcatgactag
    40441 cttacacaaa aaccaggtaa aattcaattc aaatttgact atttcacata caggtggtcg
    40501 cttatcgagt gattcgggtt tggtcttagt tcaagaggtg atgaatacct tcggcttttc
    40561 acacgtagct aaacagtggc tccatattaa agacaaacgt gtttacttca cacatgataa
    40621 cttagcgata ttagaacaac tcattatgca gttaattgct gggtactcgg cagactcatc
    40681 agctaatcta ttaagacagg atccagtctt tcaagctgta ctcggtaaaa aagagttggc
    40741 ctcacaatcg tcaatctcac ggtttttaga tcgtttcacc gaggagaaca tggatcaact
    40801 ccaagcatta aatcagtcgc tgattgataa agcgcgtttg attcgcaatg acaccgagtt
    40861 aatcattgat gtcgattcca cacattcgga tacctttgga cgccaagaac aaacagatta
    40921 taatgcccat tatcaaacct acggctatca cccattagtt gcatttgacg gattgaccgg
    40981 agatttccta aaagctgaac tgcgttcagg caatcagtac acgtctaaag gggtaaaagc
    41041 ctttatcgac ccgctgttac accactacaa gagcacgtta cctcataccg agatattggt
    41101 tcggggtgac agcggcttcg ccacaccaga ggtgtatgaa tcttgtgaag caactgaaag
    41161 ccagtacgtt atccgattaa agagcaatcg gaggttaagt cagttagctg aacactctgt
    41221 tctttatggg gataataaaa aatgggaaga ccgagaaata cagtattttt cactccctta
    41281 tcaagcacaa tcctggtcaa aaccccgtcg cgtttgtatt cgatcaatcc gtgaagcagg
    41341 agagcttctt tttcaccacg cattcattgt gacgaatcta tccgataatg tctcgcctga
    41401 agtcatattc tctctttacg gcaagcgtgg aacaatggaa aatttcatca aagaagcgaa
    41461 atcaggcttt tattttgaca aaacagatag tccgcgtttc ctggaaaatc atgtcagaat
    41521 gatgatcagt gtcctggctt acaacctcgt caatttttta aagaccattg gatttgaaca
    41581 agtgaatcgg gggatgacga ttcattctat acgattgaca ttgcttaaag ttgccggaaa
    41641 actcgttaaa acaggtagac aagtctatct caaactgtcg agttatcatg tgtatcaaac
    41701 tgaattttat aaggtttttg aacgcctacg gcgatctagg caatggattt aggctagtta
    41761 tcgtaaaaat ttttaaccta tttttccaag gggtcagtct gcccttaaat agacaaataa
    41821 tttttattat agccttcttc cgtatatatc ctgttcgaaa acacattatt ttggaagaat
    41881 gtatctgcct aatttaaata taggcacttt gttcaaaaaa atagcttaaa tttagagcta
    41941 tgaattattc aggtggtata tatctttcct ccatttttac aaaattccca agcaacatta
    42001 tatgcatcta tcgcattaaa tataattaaa tttaatcttt tcttactcac gatacattta
    42061 tttggtatgc tttcaaataa ttttttaaaa acatgtttat tgttattata tcctggcata
    42121 cgatctaaat actgtaccgt accccccacg tcagaaagca catatgctgt tttgtagtta
    42181 gaatagcatt ctttataata atctatgcta ttcttcaagg catacgaagc acaatgaaaa
    42241 accgtaattt tatgtggtct ttttcccatt cccattaata atactttcgc attatactct
    42301 tttgttgcta tactatatgg agaattttcg tcaaactgat aaagactgtt tttgtgtttg
    42361 cttaagattt cttcagcatg ttttccataa ccacacattg aaaatttagg gaaacaactt
    42421 ctcatagttc caggataatt ccttaaagac tcactcaata ctccagcaac agattttgtt
    42481 ttgtttaaat caaacgaact attatcttct ccatatgccg gcatgagtaa tgttccctct
    42541 tctttgccaa ttttatctaa tagcaacctt attacatcct ctggacacat atcaagcata
    42601 tacaatgctc tccatgatgc atgtacaatt aaaacatccc ctttttttac accaatttcg
    42661 tccaaatatt gtcctaactc ttccttgaaa tttttctata tggaattttc ttttcaaaat
    42721 gataatagtg tctttctatt ccatctgcta cagtctcatt ttctttaatt ctaagaatac
    42781 ttcgtaatac tttttttatc atcatacttt cccttcatgc cctcattttc cactactaca
    42841 tcacgttgat aactaaacct cggaactaaa taaatgatta tgcagcctaa caaaaagcca
    42901 tgtgtaagca taaccgtaaa aaaggatgaa cttaacagtg tatacgctga aacaataatt
    42961 attcccatac agattccact tgttaagcct tcacaaactc tatctaacaa tttaagcgca
    43021 catacaatca aaattggtaa aataacaact cctactgctc caaaatttga atatgcatct
    43081 gcaaacaatc cattattagc ataactatta tttacataat attgtccacc tacaagagtt
    43141 ggtatatctt ttgtatatgg tgatgaaaag cctaatcttc cgacaatact ctgtctaaaa
    43201 tagtctttta cattattgct aaaaaaatca aagtatgcat attgcaaata tgctgttacc
    43261 aaaaataatc ttcgtgcgac taaatttata aagttttctg ttcctataca aatcttttct
    43321 ataaatccga tgactgtaac tcccatcata attgctggaa tcattcttgc ggttaaatta
    43381 tgtataaaat agtatcccaa tattgtagca attaaaacaa atatcgttga ttttcttcca
    43441 tctgcaaaaa aagccaataa ctggcatatt gttgctgcca atgctaagat tctttttttc
    43501 ttgtttaatc cataaacaat gataaccgga aacacgataa tacatgctga aaataaatat
    43561 tgcaaaattg ttggtaactt atcactttta aacgctgctc ttgttccata aacgtcatat
    43621 aaattaaatg aaacatgaat cccagtatac gcaacacata tgagtaataa tactgctgca
    43681 aagaaaagaa acactgcata gatcagtaat gaagaccttt ttattgtatt tttacctaaa
    43741 actatttttc gtcctttgtg tttataaaaa gctaccataa agaaccagta taagacattt
    43801 aaaactgcaa attccaaatt atgacctaag aatgctacta ttgttgttgt tggaacagcc
    43861 gaacatatca atataattga taagacaact gctccatttt tctctacatc aattattgta
    43921 aacatcatca atatatagca tatgaccata atccaagaaa ccatataata aaacgtcgat
    43981 tgttctgcag tcatgcctat ataagaatat aacggtgaaa caatattaca gtacatataa
    44041 tccaataaca ctctaaaggc aataatatat atgctctgta aaaccttatt tggttttaat
    44101 aaaagatttt ttatatttgt taacatgaat ttttattctc cataatttct tgatatattt
    44161 ttacatattc ctttgataag ttgtcccatc taaatttttt acttgcttgc atacatgctt
    44221 caggaaattc attatagcgt tttaatattt ttattatatt ctcgcataat tcctcaggat
    44281 catgtgcatc aacatgatag ccaacaacac cttccgcaaa ttgcccatca aatccctgcc
    44341 ctttagaata tataactggc aaaccttggc tcatcgcctc agcatatact aacccgaatg
    44401 attccgtaaa agatggcatt acaaaaatgt ctgcatttct ataagcatca atcaattgtt
    44461 cctttggctt tgcatcttca taacaagtcg agtcttctga aataatcttc tttaattccg
    44521 ttttatcatc tacttttcca ataactaata gttcactatt tattcctttt ttctttaata
    44581 tcttcattgc tttctgcgtt gtaggtatat ttttatttct atcaatcctt cccgcataaa
    44641 ctaatctaat gaaatctttt ttttcagatt tttttatcgt atcttctggc tgattttcaa
    44701 accaaaaatc atctattcca tttggtatta caactgtttt ctcatatatc tcatttctat
    44761 atttttctgg tacatagttg tttaaaacgg tttccctata tacatttgac agaaaaaaaa
    44821 ctttttgagc ttttcgcatt atttcaattc cacgattcct gagcaaaaat ctcttagcaa
    44881 aaaaatcatt tacatcagta tttcgtacag caaccacata tggaatacca tatttgtctg
    44941 ataatttcat agccgaattt ccatcagtaa ataacgtata cgcatgaata caatcatatt
    45001 tttccaaatc aaaatcttct tctatttttt tcaaaatttt tgcttgttta aaatcaaaat
    45061 taattctatc ccacttatta aagcattctt ctatttttac atattctttt gtattaacta
    45121 tacttcgttt tttatcatat gtagctacaa atacatcatt tgaaaatcct gcagcattta
    45181 atttttcaat caaacactga tgcaatgatg acaatatgta gttacaatta atgtgcagga
    45241 ttttcatact tataactcct ctgctaaaat tataatctcc aataattcat tccagacttt
    45301 ttcaaatcag atactgaata caaacctttt acatcaagta acactttttc attgtccgga
    45361 caatctttaa acaatgcttt aatttcatcc agcgacattt ttttgaactc gttatgtgca
    45421 acagcaacaa taatacaatc tgcatttttc gcattctcta attcacttaa ttttacacca
    45481 tattcacgaa atgcatcttt ttcgtcagcc catggatcaa caactactgg atcaatatca
    45541 tatgttttta attgctttat aatatcctct accttgctat ttctcgtatc agggcaattt
    45601 tccttaaatg ttaaacctaa gattacaact tttgattttt ttggtgactg tcctgctaca
    45661 accatcgttt tcactgctgt gtctgctata taagctccca tactatcgtt aacaattctt
    45721 ccattaagga ttatttgact atggtatccc aacttttcag cttcatatgt aaagtagtat
    45781 ggatcaacac ctatacaatg tcctccaacc aatcccggtc taaatcccaa tgcattccat
    45841 tttgtattca taccatcaac aacttcattt gtatcaatac ccatgcgatc aaaaaccatt
    45901 gctaattcat tcataaatgc aatatttata tctcgctgac tattttcaac tacttttacc
    45961 gcttctgcag tttttatatt agatacagga taagtgccaa cttcaattac taaatcatat
    46021 acattcttga tttcatttaa agaatcttca tccattccag atacaatttt atgaatattt
    46081 tccagtctat gcaccttatc gcccggatta atacgttccg gagaatatcc aactttaaaa
    46141 tcttttccac attttaagcc agatttttct tccaaaatcg gaatacacac atcttctgtg
    46201 cagccaggat acactgttga ctcgtaaaca ataatggaac ctttggtcaa atttcttcct
    46261 actatttcag acgcaccaat tacaggtgtc aaatctggtg tatgatctgt attaacagga
    46321 gttggaactg caataataat aaatttcgct tcgctgattt tcttttcatc agaagtgaat
    46381 tccacagtag tcaattttac tccttcattt ccaacttcat ttgtaggatc aattcctgat
    46441 ttatataatt caattttctt ttcattcaaa tcataaccta ttacctttgc ttttttcgca
    46501 aaagccaccg caataggcat tcccacataa ccaagtccaa ctatagctat tttttcttct
    46561 ccattaa
//
LOCUS       DAKCAA010000014        44958 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000014 DAKCAA010000000
VERSION     DAKCAA010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 44958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.014"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(70..921)
                     /locus_tag="OUE31_000916"
     CDS             complement(70..921)
                     /locus_tag="OUE31_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HCU0221944.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(934..1719)
                     /locus_tag="OUE31_000917"
     CDS             complement(934..1719)
                     /locus_tag="OUE31_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCU0221945.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(2071..3012)
                     /gene="ribF"
                     /locus_tag="OUE31_000918"
     CDS             complement(2071..3012)
                     /gene="ribF"
                     /locus_tag="OUE31_000918"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HCU0221946.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(3016..3939)
                     /gene="truB"
                     /locus_tag="OUE31_000919"
     CDS             complement(3016..3939)
                     /gene="truB"
                     /locus_tag="OUE31_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HCU0221947.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(4307..6669)
                     /locus_tag="OUE31_000920"
                     /pseudo
     CDS             complement(4307..6669)
                     /locus_tag="OUE31_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            7117..7290
                     /locus_tag="OUE31_000921"
     CDS             7117..7290
                     /locus_tag="OUE31_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0221948.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(7447..7794)
                     /gene="rbfA"
                     /locus_tag="OUE31_000922"
     CDS             complement(7447..7794)
                     /gene="rbfA"
                     /locus_tag="OUE31_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HCU0221949.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(7821..10127)
                     /gene="infB"
                     /locus_tag="OUE31_000923"
     CDS             complement(7821..10127)
                     /gene="infB"
                     /locus_tag="OUE31_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCU0221950.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNPNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(10140..10451)
                     /locus_tag="OUE31_000924"
     CDS             complement(10140..10451)
                     /locus_tag="OUE31_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HCU0221951.1"
                     /translation="MNTVNRQEAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(10448..10741)
                     /locus_tag="OUE31_000925"
     CDS             complement(10448..10741)
                     /locus_tag="OUE31_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HCU0221952.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(10763..11938)
                     /gene="nusA"
                     /locus_tag="OUE31_000926"
     CDS             complement(10763..11938)
                     /gene="nusA"
                     /locus_tag="OUE31_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HCU0221953.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(11961..12434)
                     /gene="rimP"
                     /locus_tag="OUE31_000927"
     CDS             complement(11961..12434)
                     /gene="rimP"
                     /locus_tag="OUE31_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HCU0221954.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(12579..16937)
                     /locus_tag="OUE31_000928"
     CDS             complement(12579..16937)
                     /locus_tag="OUE31_000928"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HCU0221955.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(17149..18858)
                     /locus_tag="OUE31_000929"
     CDS             complement(17149..18858)
                     /locus_tag="OUE31_000929"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCU0221956.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(18926..20194)
                     /gene="rseP"
                     /locus_tag="OUE31_000930"
     CDS             complement(18926..20194)
                     /gene="rseP"
                     /locus_tag="OUE31_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HCU0221957.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(20355..21155)
                     /locus_tag="OUE31_000931"
     CDS             complement(20355..21155)
                     /locus_tag="OUE31_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HCU0221958.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(21152..21964)
                     /locus_tag="OUE31_000932"
     CDS             complement(21152..21964)
                     /locus_tag="OUE31_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HCU0221959.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(22159..22716)
                     /gene="frr"
                     /locus_tag="OUE31_000933"
     CDS             complement(22159..22716)
                     /gene="frr"
                     /locus_tag="OUE31_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HCU0221960.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(22719..23441)
                     /locus_tag="OUE31_000934"
     CDS             complement(22719..23441)
                     /locus_tag="OUE31_000934"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HCU0221961.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(23577..24458)
                     /locus_tag="OUE31_000935"
     CDS             complement(23577..24458)
                     /locus_tag="OUE31_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HCU0221962.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(24557..25339)
                     /gene="rpsB"
                     /locus_tag="OUE31_000936"
     CDS             complement(24557..25339)
                     /gene="rpsB"
                     /locus_tag="OUE31_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HCU0221963.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            25698..26177
                     /locus_tag="OUE31_000937"
     CDS             25698..26177
                     /locus_tag="OUE31_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HCU0221964.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            26394..27485
                     /gene="phnW"
                     /locus_tag="OUE31_000938"
     CDS             26394..27485
                     /gene="phnW"
                     /locus_tag="OUE31_000938"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HCU0221965.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKELLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            27478..27606
                     /locus_tag="OUE31_000939"
     CDS             27478..27606
                     /locus_tag="OUE31_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCU0221966.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            27610..28155
                     /locus_tag="OUE31_000940"
     CDS             27610..28155
                     /locus_tag="OUE31_000940"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCU0221967.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(28609..30300)
                     /locus_tag="OUE31_000941"
     CDS             complement(28609..30300)
                     /locus_tag="OUE31_000941"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HCU0221968.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(30720..31667)
                     /gene="arcC"
                     /locus_tag="OUE31_000942"
     CDS             complement(30720..31667)
                     /gene="arcC"
                     /locus_tag="OUE31_000942"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HCU0221969.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(31782..32801)
                     /gene="argF"
                     /locus_tag="OUE31_000943"
     CDS             complement(31782..32801)
                     /gene="argF"
                     /locus_tag="OUE31_000943"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCU0221970.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(32892..34121)
                     /gene="arcA"
                     /locus_tag="OUE31_000944"
     CDS             complement(32892..34121)
                     /gene="arcA"
                     /locus_tag="OUE31_000944"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HCU0221971.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            34582..35283
                     /locus_tag="OUE31_000945"
     CDS             34582..35283
                     /locus_tag="OUE31_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCU0221972.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(35892..36908)
                     /gene="tsaD"
                     /locus_tag="OUE31_000946"
     CDS             complement(35892..36908)
                     /gene="tsaD"
                     /locus_tag="OUE31_000946"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HCU0221973.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(36905..37369)
                     /gene="rimI"
                     /locus_tag="OUE31_000947"
     CDS             complement(36905..37369)
                     /gene="rimI"
                     /locus_tag="OUE31_000947"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCU0221974.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(37376..37918)
                     /gene="rimI"
                     /locus_tag="OUE31_000948"
     CDS             complement(37376..37918)
                     /gene="rimI"
                     /locus_tag="OUE31_000948"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCU0221975.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(37902..38624)
                     /gene="tsaB"
                     /locus_tag="OUE31_000949"
     CDS             complement(37902..38624)
                     /gene="tsaB"
                     /locus_tag="OUE31_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HCU0221976.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(38815..39795)
                     /locus_tag="OUE31_000950"
     CDS             complement(38815..39795)
                     /locus_tag="OUE31_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0221977.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(39819..41303)
                     /gene="galT"
                     /locus_tag="OUE31_000951"
     CDS             complement(39819..41303)
                     /gene="galT"
                     /locus_tag="OUE31_000951"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HCU0221978.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(41315..42304)
                     /gene="galE"
                     /locus_tag="OUE31_000952"
     CDS             complement(41315..42304)
                     /gene="galE"
                     /locus_tag="OUE31_000952"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HCU0221979.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            42552..42719
                     /locus_tag="OUE31_000953"
     CDS             42552..42719
                     /locus_tag="OUE31_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HCU0221980.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(42781..44592)
                     /locus_tag="OUE31_000954"
     CDS             complement(42781..44592)
                     /locus_tag="OUE31_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HCU0221981.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(44589..44954)
                     /locus_tag="OUE31_000955"
     CDS             complement(44589..44954)
                     /locus_tag="OUE31_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HCU0221982.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
BASE COUNT        12235 a         9622 c         7919 g        15182 t
ORIGIN      
        1 tttataagta cttactgttt ggttcaaaca aatatttttt taataaatga aattttacca
       61 tctttatcct caaataaaga ccgtgaccat gcttcctact acgatcagca ataatccgat
      121 aatcgttaat tttttttctt ttggtgtctt attttcatgc aggatgtaca taccgcctaa
      181 tgtagagata actacgttta gctgtgtaat gatatatgca gtagcaaccc cattttcatt
      241 tgctgaaaaa atataagcca atgctgacac actaaagatg gctccaacga tcgttgcttt
      301 ccaactcttg tcttcagaaa atgcggttgg tttacggaaa atcacataaa tcactgcccc
      361 taaaaagaca ccgatcattt gcggaaagaa aatggaaagt ccgcttgcat caactagttt
      421 aggcaatgca ctgtataccc aataaccaat acttgttgat gctaatagac taattccttt
      481 tgtgataccg cctttttttc caggatcatc actgattgcc gttaaagcag aaccaaatac
      541 aagaagaatg attgctgctg ctccaatgat tttccccata cttccagacc attctccaaa
      601 agcgaagaca ccaatcaacg aggttccgac taactgtaat gcagtcgaaa ttggcatcgt
      661 tttagaaaca ccaatcaagt tgaaagatgt atactgtcct gtttgtccaa taacccaaaa
      721 tgcaccagaa agtaaactaa tcaaaaatgt agtcactgaa ataccagctg gagaagcgaa
      781 taattgaacg agtaagccga caagcaccgc tccaatacca gttcctaata tctcatttgt
      841 tggtctgcca ccaatctttt tcaaaatcag tggctggatc ccccagccaa ctgccgggat
      901 caatgcaatc aataaaccca tttttattca cccttatcct tttccacctt ggaaagaagg
      961 atataaagtc atcccaccat ctgcaaatag tgtaatacct gtaacataac tggattcgtc
     1021 tgaagccaac catgcagctg tcgccgctat ttcttttggt tcacctacgc gtcctagtgg
     1081 gatcatactt tccaagagtt ctttttgttc aggatcatca aattttgccg cattaatagg
     1141 tgtacggata gcaccagggc ctatactatt gattctgatt cccttcggtg catactccat
     1201 tgctaccgtt tcggtaaata attttacccc gccttttgaa gcagcgtaat gagcaaacgt
     1261 tggccatggg atctgttcat gaacagaaga catattgatg atatttcctt ttttattatt
     1321 ctctgtaaag taatttaaag ccgctttcgt tccgataaaa acgccagtca aattgacttt
     1381 taacactctt tcccaatctt caaggctaag ttcatgggtt ggatgctgat tttccatccc
     1441 agcattatta acccaaacgt ccagtgtccc aaaattttct aaagccgtat caagtaaacg
     1501 ctgtattcct tcttcagaac tgacatctgc ttgtacagag actgcttttc cgcctgcctc
     1561 ttcgattgct ttgactgctt tttctgctcc ttctttatcc gagttatagt tgacaactac
     1621 attcattttt tctttcccga atcgttgagc aatcgctgtt ccaatcccct ttgagccacc
     1681 agttactact gcgactttgt tttctaattc cttgtacata gtacccactc ctttttcata
     1741 cctaaacctg ttattacgga taacttttat ttccgcctta aagtgagtgt acaccaagat
     1801 atatagtcta aagcaaatga tacgctctag caatcgtttt catgaattgc tagtgtcctt
     1861 ttatttctat aaagaaagag gttgtgacag aagtggtcag cttcaagaaa tttcggctta
     1921 tttccgaaga agctacttct gaaaaaccat ttatttggaa aaaaaggctg tgacaagact
     1981 tttgtcacag cccctttcct gggcttattt atcacccatt ttattgtaat tgctagttat
     2041 acataaacaa gagattttat gcataatgtt ttattgctga gaaaaatatt cagctgttgc
     2101 ttgttcatcc tccttgagtt gttcaatcaa ttcctctaca ctagaaaatt tcacttgatc
     2161 tcttaaaaat tgattccagc gtaccgcgac atgttcacca tagatatctt gattaaagtc
     2221 caaaatatac aactctacag tcagctcccg tccttcaccg aatgtatcat tatgtccaat
     2281 tgaacccatg gctggatacc atgtttcccc aatttttatt tccgacacat aaacaccttc
     2341 tttaggcaaa tgaaccgtgc tctttacttt gacatttgct gtagggaatc ctagtagtct
     2401 gcctcgtgca tcgccatgga caactacccc ttctacctca tatgtgcaac ctaatagttt
     2461 tgctgcttct tttacttgtc cgctgtctag taatccacga atacgggtag agctgatttt
     2521 ttcaccttgt tcttcttctt tagaaactgt gacgattttg aatcttcctt tggcatattc
     2581 aggaaaatga gcgacatctg caatgtcttt tggtccatac gtataatcaa aaccggaaac
     2641 agcatatttt gcatgtaacc ctacgatgta ttgatcaaca aattcctgcg gtgctaaatg
     2701 agcaaaagaa gaagtaaaat caacttcata taaataatct atacccaaag cggccatttt
     2761 ttcttctttt tgcttaaggc tagtcaaata tttcacgctg ctaggatcga tctttttaaa
     2821 gacaatagat ggatgctgat tgaaagtcat caatgctaat ttcaatcctt ctttttgtgc
     2881 aatttccata cctgtcttta tgactttctg gtgtccgata tgcacgccgt cgaaaaatcc
     2941 cagcactaaa acgacatcgt cttctggaat ttgttctgat tggtaaggat gtctgatctt
     3001 gatgatattc attcgttatt cctcatttct caatacttta ctaggtttta atttgttttt
     3061 ttctttcggg tttggctgat aaatactgac aacttttcct ttataaaaca aagcaatttc
     3121 ttctgacggc atttctggga gcgcaaatac agtataatca agtctcatac cgttttttac
     3181 tttctgccat acttcatcag taatatctac tcgtttgaac cgttccactc ctttttctat
     3241 tggcagcaaa caatcatcga ttgtcccatt tttcacagct tgagctactt cttctaatgt
     3301 cagagcatcc ttctgggaca taccggcact tgctgttcgg gtcagatcag acatgtgcgc
     3361 agggtaacca agtttcttgc ctgtatctac agctaatgtg cggacatagg ttcctttccc
     3421 gcattctact tcgaagcgcc aagaaatggt tcctgtcact tcgtctcttg tcaattcact
     3481 tgtccggata aaacggtaaa tctgagcctt tctaacagga cgctccactg tttcattatt
     3541 gcgggcatat tcatataacc gcttaccgtt gacttttacc gctgagtaca ttggtggtat
     3601 ctgggtgatc tcaccaataa atgaagccat cacttcatct attttttttt cagataaaga
     3661 catatctact ggttttgttt ctacccgttc tccggatcga tcttccgtcg ttgtactgaa
     3721 acctagagtt atctcgccta catagatttt cccagaatct gtcaaatatt cgataacttt
     3781 tgtggctttt ccaatacaaa tgggcaacac accgtctacg tctgggtcaa gcgtaccccc
     3841 atgtccgatt tttttcgtat gtaagatttt tcttaatttg aatacgcaat catgacttgt
     3901 cattccgcgt tctttccata aaggtaataa cccgtccatg tcttttctcc atttcatttt
     3961 tgatttaact gaattattat aacacattgc atcaattact gacgaatttg acatcataat
     4021 gaacggtttt tatttttcgg caataaaaac gtaacaaaat tcatgctcac gtaaatagaa
     4081 atcatgttat gcttttttaa aggagggaat agaatggaag attttttctt tgcaccattt
     4141 gattggattt atgggtggct tacaggtaaa tagtttggtt ttcacttccc aaaaacgaaa
     4201 aaaaagactg gccattcttc cagtcttttt tccgtttttt ttatttattt tttcagtttc
     4261 ttaatcaatg taaaaaattc tattttgcgg gatcgatttt atcattttat tggtcaagat
     4321 ttttccattt ccaatccaat acttctggca gatcaatacc attttcacga atatagtttt
     4381 gatgttcttg taatttctga tccatttttt tcgcaaaatc ttctgcttga cttcctttga
     4441 tttttaaagc tgcgtctttt gccaaatgat aacgatcaag ttcatttact acacgcatgt
     4501 caaatggtgt cgtgatatct ccattttctt tgtagccatg aatcattaaa tgatggttat
     4561 gacgatcaaa gaaaatcgtg cggaccaatg tttcataacc gtggaaagca aataagatcg
     4621 gtttgtcttt tgtaaaatat tgatcaaatt cttcatcgct caacccacgc ggatcttgac
     4681 ttggatgacg taatttcaat aaatctacga cattgatgaa ccgaattttt agttttggga
     4741 attcttccag cagcaaagtt acagctgcta atgcttctaa gttagattcc gttcctgcag
     4801 cagcaatgac caattcaggt tcctcctctt ttgctgtcga agcccaatca atgattttca
     4861 agccttcatt cactaagacg gctgcttctt ctgctgagta aaattgagca cgcggatgtt
     4921 tggaagagat gatcaaattg attttttctg acgagcggaa tgctttatcc atgactgcga
     4981 gcaatgtatt tgcatccgca ggcagatatt cacggatgaa ctccgccttc ttttctgcca
     5041 aatgtgtcaa tattcctgga tcttggtggc tatatccatt gtgatcttgc tggaagactg
     5101 ttgagcttgc aatgagattt agcgaaggat aatcatttcg ccaagaaagg tcatgtgatt
     5161 tccgcatcca tttgaagtgc tgagtcaaca tagagtcaac cactcgcaag aatgattcgt
     5221 aacttgcaaa aaaccatgcc gtccagtcag aacgtaccct tctaagaacc cttcatcttg
     5281 gtgttccgat aattgactgt cgatgacgcg accagatggc gaaagccatt catcattttc
     5341 tggttcgatt ttttccatcc attggcgatt tgtcgttttg aaaacttgat tcaatcggtt
     5401 tgattttgtt tcatctggtc caaatatacg gaaattttct ggatttttct caatgatctc
     5461 gcgaacgaat ttaccaagtt cggtcatatc ttctgcttta acggagcctg gtttttcaaa
     5521 ttgcaaagta tattttttcc aatctggcat aataagcggt cttggatcga ttccaccatt
     5581 ggtgatagga ttttttgcca ttctttggtc accagtaggc gcgatttctc tgatttcttc
     5641 taaaatacgt ccttgtgcat caaataattt ttctggttca taggatttca gccaacggag
     5701 taaagcatct gcatgatcca tatgttcttg atctacagga atcggtactt ggtgtgctcg
     5761 gaaggttcct tcaattggtt ccccgtccca ttcttttgga ccggtccatc cttttggtgt
     5821 gcgtacgatc aatactggcc attttggcat cacgacatct gttgctgtct tcaggcgagc
     5881 ttctttttgg atggatttaa ttttctcgat tgcttgatcc attttttcag ccataacagg
     5941 atttaatttt tctgaatcat ttccttcaat aaagaaaggt tcccagccaa gtccgttaaa
     6001 gtaatttgct aattctccat ctgatttacg tgccaagatc gttgggttgg ctatttttgc
     6061 accatttaaa tgaaggatcg gtaaaacagc tccatctatc actggattga taaagacatt
     6121 tgagaaccag cttccagcta aaggaccggt ttccgcttca ccatcaccaa tcacgacagc
     6181 agagattact tcaggattgt ctaatacagc tccgactgca tgtgaaagag agtatccaag
     6241 ctctccgcct tcatggatag aacctggtgt ttctggtgct gcatgagaag caatgcctcc
     6301 aggaaatgaa aatcgtttga ataatttttg cattcctgtc tcatcttccg ttacttctgg
     6361 atagatctct gtgtaacttc catctaaata agcattcgat accatgactt gtccgccgtg
     6421 tcctggccct tcaatataaa acatgttcaa atcatattta ttgatgactc ggttcaaatg
     6481 gacataaata aaattttggc caggaatcgt tccccaatga ccgattggat gttttttgac
     6541 atcttcgggt ttcagtgtac gtctcagtaa ggggttatct ttaagataaa gttgcccaac
     6601 agaaagataa ttagcagcac gccaccaagc cgtcatttta tcaaagtatt ctttactaga
     6661 ataatccata cataacactc cttttcatta ttactcttat tctagcgcag atactcccaa
     6721 ttgaaaccta ataagcactt ctgttcattt gtttggattt tatatctagc caaatgaaca
     6781 ggtataaaaa accacgaaat ttttcctttc gctgacgttt tttacattga tccaaaaaac
     6841 ttgtcgttat cacaatggct gttccgcagt tcatttcgct cctcatcatg cataatttgc
     6901 tgaatgacgc tgggccagtt aacacattgc tggaaaactg gggctggatc gagcaattcc
     6961 tttcctgatt gatccgtttt atgtaaaagt ctctgttatc tttgtcaata tgtgaattgg
     7021 tatcccagct actatgctaa tttctacagg gattatccaa aatttggatc gtgaccaaat
     7081 cgaagcggcg taatcggaaa tatcaataac ttcaacgtga tttttctttt aactgtcaac
     7141 ggaccgacaa actcaaactt ttatggtgca ggttccactg atcttctagt tacttggcta
     7201 tacctgactg tcactaaaat agattacaat ctagcttccg ttatcggtat cttgatcttt
     7261 atctatatgc aaaaatttat atactactag aaaaaagaaa gtcgaatttt ttacttttct
     7321 ttttctcttt tttggttagc tgacacgccg caagactaaa gtcatggaac tcttaggtaa
     7381 tacgtcttaa tgaaaacaaa aaaatcccgc aacccctgat ttcacaggat ttgcgggagt
     7441 ttttgattag tctttgttca agtcgcgaag caattcatcg atatggttgc catagacaac
     7501 tgattcatca agttcaaaga acaattcagg tgtcttataa atacttagat tgtgccctaa
     7561 ctctcgacga atcaatcctg atgctttatt caatccatct tgtgctgttt tcttatctga
     7621 tgctaagtca gataaaatgc tgtaatagat cgttgcttgc tgtaagtccc ccgtaacttt
     7681 cacatctgtg atcgttacgt tctccacacg agggtcacgg acctttttgc gcaaaatatc
     7741 attgacttct tttaagattt cttgaccgac tcggcggtca cggtagttag ccataatgat
     7801 tggcctcctt ttatcagttt ttagtcattt ttgacttctt ccatgataaa tccttcaatt
     7861 acgtcatcta ctttgatgtc attgaatttt tcaatcattg caccacattc ataacccatt
     7921 ttgacttctt tcacgtcatc tttgaatcgt ttcagacttg caagttggcc ttcatagatt
     7981 acgattccgt cacggattac acggacaccg ctatctctac gaatatatcc ttctgttaca
     8041 taggcacctg caatcgtacc aactttagaa actttgaagg tttcacgaac gatcatttga
     8101 ccggtgattt tttcttcaaa ttcagggtct agcatccctt tcatcgcagt ttcgatttct
     8161 tcgatggctt tatagatgat acggtgaaga cgaatatcga cttcttcagt atcagcttgc
     8221 acttttgcct gcggtgtagg acgaacgttg aaaccgatga taatagcgtt gctggctgct
     8281 gctaaggtta catcactttc attgattgct ccgacagctg aatggacgat ttttacacgg
     8341 acaccttcca catcaatctt cttcaatgat gcagccagtg cttctgctga accttgtaca
     8401 tctgctttga tgattacgtt aacttctttc aattcgcctt ctttcaggct ttcaaataag
     8461 ttatccaaag tcacacggct tgtggcagca cggttttcta ataatgcacg tttcgcgcgt
     8521 tcttcacccg ctgcacgtgc tgtcttttcg tcttcgaaga ctacgaaacg gtcacctgct
     8581 tgaggtacat cattcaagcc agtgatttct actggcgttg caggtcctgc ttctttatcg
     8641 cgacggccaa gatcgtttgt cattacacgg acacgtccgt aagtattacc gacaacgatt
     8701 gggtcaccaa catgaagtgt tccttcttgg acaagtaagg ttgacacagg acctttacct
     8761 ttatcaagac gtgcttcgat cactgttccg attgcgcgtt gtgttggatc tgcttttaaa
     8821 tcttctactt ctgcgactaa caggatcatt tccagcaatt cttcgatgtt ttggccgaat
     8881 ttcgctgaga tctcaacaaa gatcgtttct ccaccccatg cttcaggaat taactcatac
     8941 tcacttaatt cttgcataac atgttgaggg tttgcacctg gtttatcaat tttatttaca
     9001 gcgacgatga ttggaacgcc tgcagctttg gcatggttga ttgcttcaac tgtttgtggc
     9061 atgacgccat catctgcagc aacaactaag atcgtgatat ctgtgatact tgctccacgt
     9121 gcacgcatac ttgtaaaggc cgcatgtcct ggtgtatcca agaaagtgat tggtttacca
     9181 tcaatatcga tctggtaggc accgatatgc tgtgtgattc cgccggcttc gccgcttgtt
     9241 acacgtgaat ggcgtaatgt atccaataaa gttgttttcc catggtctac gtgtcccata
     9301 atcgttacga ctggcggacg tgagactaat ttatctggat cgacttcttc tgcctcgaag
     9361 aatttatcga tatcagcaat gtcaacttgg actttttctt gtggttccat gccatagtcc
     9421 gtcgctaaca gttcaatcgt atctttatcc agtgcttggt tttgattgac catgacacca
     9481 agcataaata attttttaat gatttctgct ggctcacgat gaattttttt cgcaatatct
     9541 gctacgttca taccttcagt atactctaat acatctggca attcacggaa tttgcgtggt
     9601 ggtacagctg gtttagttga ttgttgctgt ttgccttttt tacctttttt attataacga
     9661 ttacggttat tattattaaa tttgccgcga ttgttattgt ttggtttgtt gttattgtta
     9721 gtacggtttt gattgccgcc ttggctcgtt ccttgacgat tttggctgct ggtatttccc
     9781 gtattatttg ggtttgttgt tggttttttt ccttgattca cttgaccgct cccttgaccg
     9841 cgatcttgat aactgcggtt atttttattt ttttgttgat tgttcgttgt ttctttttta
     9901 cgttgatcgt tcggctgttg attggctggt tttctgcttg cttgttgtgc agcttgttgt
     9961 ttcgtgcttg ggtttttgaa cgcttgttgc aatttcttct catcattgct agtaatcgca
    10021 cccatatggt ttttcacatc gatgccaagt tgttgtgctt tttccacgac gtctttacta
    10081 gattttttga gttcttttgc taattcatag attcttttgt tgcccatgca atcaccttcc
    10141 taaccttcaa ttagctcctt ggtcttcttc gcaaatccgg catccattat tccgaatacc
    10201 ttgcgaggtt ttccgatcat ctgcgtgatt tctgcttcag aaaatagctc aaagcaagga
    10261 acttcataat atgaactctt atcttttatc ttttttcttg tattctcgct tgcatcggtt
    10321 gccacaaaca ccaattttgc tttttgtttg cggatttcag caatggtcag ttcttcaccc
    10381 gtgattagtt ttcccgcgcg catcgctaga ccgatgagat tcatggcttc ttgccgatta
    10441 actgtattca ttttccaaat aactctttac gtgctttttg gtgagtgaca tagtcaagaa
    10501 gttcttgata aaactcatct gttaatgttg tttcgagtac tcgatcgaga atttttttat
    10561 cccaagcttg ttgtacttct tccggctcaa gtgagacata cgctcctcgt ccaggcattt
    10621 ttccagttgg atcgatcgat acttcccctt cttttgaacg ggtgattcgg accatctctt
    10681 ttttaggttt catttcacct gaaaccacgg atttgcgtaa aggaattttc ctttgtttca
    10741 tctctttgcc tccttactaa agttaagctt ctggtttttc ttcgaccgtt tcattgttga
    10801 atgcaattgt ttcatattca tcgtctgtta aatctgactg aacgattgct tcatcatgca
    10861 gttcttctgt ttctttttgt tgttcttgat tttcataaaa ttccgtcatg tcagattctg
    10921 atttgatatc gattttatgg ttagtcaatt tagcagctaa acgtgcgttt tgtccgcgtt
    10981 taccgattgc tagcgataat tggtagtctg gaacgacaac tgtgcaggcc tttggatttg
    11041 tctcatcgaa gatcacatcc atgacttgtg caggattcaa tgcatttgca atgaatacag
    11101 ctggatcttc attccattcg acgatatcca tgttttcgcc ttttaattca ttgacgattg
    11161 cttgaactcg ttgtcccttt ggcccgacac atgtaccgac tgcatcgata tttggatcat
    11221 ttgagcgaac tgccactttt gaacgatcgc cagcttcacg ggcgatgctg acaatttcaa
    11281 cgattccatc atagacttct ggtacttctt gctcaaataa gcggcgcaat aggtctggat
    11341 ggctgcggct aacaaatact tgcggacctt tagacgtatt ttctactcgg gaaacataaa
    11401 ctttgattcg atcatgtggt tgataaaatt catttggcat ttgatcttgt ttagaaagaa
    11461 ctgcctcaat tttaccaaga ttgacataaa tataacgttt atcctggcgt tcgacgattc
    11521 cttgcatgat gtctttttca taagcactga attcgttata aataatcgtt ctttctgctt
    11581 cacgtacacg ctgtaaaata acttgtttag ccgtttgcgc agcgatccgc ccaaaatctt
    11641 ttggtgttac ttcaaaacgg atcgtatcac cgatctcata tgctggattg attaaaagtg
    11701 catctttcaa tgagacttcc aactgtgaat ccatcacttc ttccgttact tcttttaccg
    11761 catagacatg gatctttcct tttttctgat caaattccac ttcgacgttt tgtgcttggc
    11821 catagtgacg tttgtatgca gaaaccaatg ctgcttctaa agcatcgatc acgatttctt
    11881 ttgagatccc tttttcagct tctaaagcgt ctaacgcatt taacatttct ttactcattt
    11941 tttctgattc ctctccgtga ttaaaattgg atagctaagc gagcttttgc aatatttttt
    12001 cggtcaaaag tcaattcttt ttctcgtgtt tttatgcgta ttttcaatgt aagctgttca
    12061 gcatcaaatg attgaagaaa tccttcatat tgtttttcgc catctactgg ttggtataag
    12121 gagacatgga cataatcacc aagtgccttt tcatagtcgc tttctttttt caatggccgc
    12181 tctgctcccg gggaggatac ctccaggaaa taggcttgag gaatcggatc tggatctgct
    12241 gcatcaagtt tttcactcag tttctcactg acaaaggcgc attcttcgat atcgataccg
    12301 ccttctttgt caataaatac tcgtaagaac cagctttttc cttcttttac aaattcgact
    12361 tcgacaagtt caaaattttg ttcatctaaa atcggtgtca ccatttctgt gactgtttca
    12421 acgacgctac tcaaaagttt cgcctcctta aaaaattaag tgcgtaattc cattaaaaag
    12481 agtgagcgaa aaatccgctc actcacagtt agtatcatta cctataagaa ctataccata
    12541 ctctgcttaa aattacaagc agacaggaaa acagatgctt atagcatatc gaataacgat
    12601 aattgatttt catctggtag atctttcaat acgccattgt cgttcatata ttcgatcaat
    12661 gtttttgaaa ctttaccgcg ggtggcaaga tcttctttgg ataaaaatgg accgtctttt
    12721 cttgcttcaa cgatttgttt tgccacgttg gttcccaaac ttgggacagc tctaaatggt
    12781 gcgatcaacg tatcaccttc aataacaaag ttaacggcat ccgatttata caaatcaatc
    12841 attccaaatt tgaatcctcg ttccagcatt tcattggcta actccagcac tgtcagttga
    12901 ttcttttctt ttacggaagc atctaatcct ttgtccgtga tttctttcat tgcttgtttc
    12961 acagcatctt ttcctttgca catggagact agatcaaagt cgtctgcacg tacagaaaag
    13021 tatgcacagt aatacaaaat agggaaataa accttgaaat aagcgacacg aagagccatc
    13081 aatacgtaag ctgcagcatg ggctttcgga aacatatatt tgatttttga acaagaatcg
    13141 atataccagt cgggcacatt attttctttc atcgccgata gataggtttc tcgcaattca
    13201 tcagggatct tgttccattg tcctttacga acagtttcca tgattttaaa tgccatcccg
    13261 ctatctaatc cagcatggat caaataaacc ataatatcat cacgacagcc gattacttcc
    13321 gccagtgtcg catctcctcg tcgaatcaat tcttccgcat ttcctaacca tacgtctgta
    13381 ccatgagata gtccggaaat ttgcagtagt tctgcaaaag ttgtaggatg cgtttcttct
    13441 agcatccctc gaacaaaacg agtgccgaat tctggaatac ctaatgtccc tgttttggaa
    13501 taaatttgtt cctgacttac tccaagtact tcaggaccgg caaatatccg catcacttcc
    13561 gggtcatccg tagggatcgt ttgtggatcg atccctgata aatcttgaag catccgaata
    13621 acagttgggt catcatgccc tagaatatct aatttcaata cattatcgtg aatcgagtga
    13681 aaatcaaaat gagtcgtttt ccattccgaa ttttgatcgt ctgctggata ttggatcggc
    13741 gtaaaatcat agacatccat ataatcggga ataacgatga tcccccctgg atgctggccg
    13801 gttgtccgtt tgactccagt agcgcctttt gctaatctgt cgacttctgc acttcgaaac
    13861 tgcagattat tgtccctttc gtatcctttt acatagccat atgctgtttt gtcggcgact
    13921 gtaccaatcg ttccggcacg gtaaacatag tcttcgccaa acaatacttt cgtatagtta
    13981 tgggcttctg cttgataatc acctgagaag ttcaaatcaa tatcgggcac tttgtctcca
    14041 tggaatccta aaaatgtctc aaatggaata tcatgaccgt ctttgtttaa gcgtgcacca
    14101 cattttggac attgtttttc tggcatgtca aatccagaac catacgtacc atcttcaaaa
    14161 aactcggaat attggcactc tggacaataa taatgagggg ctaacggatt aacttcagtg
    14221 attcctgtca tcgtcgcaac aaagctagag ccaacagagc cacgtgaacc tactagatag
    14281 ccatcttcat tacttttatg cactagtttt tgggcgatca gataaataac cgagaagcca
    14341 ttaccattaa tagaattcaa ctcttttttt aatcgttttt gaatgatctc aggtaacgga
    14401 tctccgtaca tttgttttgc ttttgtgtaa ctcaattctg atatttcatc ttctgaacct
    14461 ggaatcttcg gtgtataaag ttcatctttg actggaatca cttcttcgca gatatctgcg
    14521 attttattcg tattttctac tacgatctct ttcgctgttt cttcccctaa aaagtgaaat
    14581 gcagttagca tctcatcggt tgttcggaaa tggacatccg gcaaactatg acgattcaac
    14641 ggattcgctc cgcccataga attgatcaaa atttttcggt aaatggcatc ttcttcgttc
    14701 agataatgta cattacctgt tgcaacaacg attttatcca aactttttcc gatttctacc
    14761 aaattttgga taatttcttc caaatcatgt tcatttttta ccaattcttg ctcgatcaaa
    14821 ggcgcataga ccgcttttgg cataacttca atataatcgt agaattttgc tcggtttctt
    14881 gcctcttcta cccctttttg catcatggct tcgaatattt ctcccttatc acaagctgag
    14941 ccgatcaata gattttcacg catctttttc aattgggagc gtggtattcg tgggacgcgt
    15001 tcgaagtatt cgacattcga cattgaaatc agtttgaaca aatctttcag tcctgcctga
    15061 ttttttgcta aaatcgttac atggaaaggt cgagcccttt tgtaagaatc tccttctccg
    15121 atatgctcat ttagctgatc atgataaagc atgttatgat tgtccattgc ctctttcaca
    15181 aagatccatg ctaagtgacc agttgcttca gcatcataga ttgctcggtg atgctgttcc
    15241 aagctgacac caaatttttt agataacaca cctaatccga aacgtttgaa ttgaggatac
    15301 agatatctag ctaattccaa cgtatcaatg actggattgg ccgcttcagg aataccatac
    15361 cttgcgtagc tagtattcaa gaaccccata tcaaaagccg cgttgtgggc taccaaaatt
    15421 gtatcttttg aaaattcaag gaacatccgc aatacttctt cttccgactt tgatcctcga
    15481 accattccat ccgtgatacc agtcagatct accgttgttc gtgacaaagg atgtcctgga
    15541 tcgataaatt catcaaagct ttcgatcaca tttcctttat acattttgac tgcggctagc
    15601 tcgatgatcg tgtcatatac tgcagacaat cctgtcgttt ccacgtcaaa tacgacatat
    15661 gtggcttcac tcaatgcttc atgtgcatca ttataagcaa ttgggacacc atcatctacg
    15721 acattcgctt ccacgccgta taagattttc acacctgctt tttttccagc actatgtgct
    15781 tccggaaagg cttgcgcacc accgtggtct gtaatggcga tagctcggtg tccccatttc
    15841 cctgcttgtg ccacaagatc agagatgctg tttgttgcat ccatcgtact catattgcta
    15901 tgaacatgaa gctctactcg tttttcccct tcaggagcat aatctttgcg aggtgtatgt
    15961 ttgacttcta tgatatcttg cgcattcatg accaaatcac ggacaaacgt atcttcttga
    16021 atacttcctc gtacctttaa ccagctaccg acactgatcg catcaaatac ttgttcatct
    16081 ttttcgccgt tcgagaattt tttgacgata aatgatgaag tataatctgt gattttcaaa
    16141 gtcaagatct tgcgttttga acgtagttct ctgacttctt tgtcgaatac gtacccctca
    16201 agtgtgactc ttcgttcttc ttcaacgata ctgatcattg gtgtcgttgg ttcatcggct
    16261 ggaatatttc gtcctagctg gatgtggatg ggtccttcaa gagctggcga ttgctctttt
    16321 ctttcctttt tcttttgttc gtggacaact agactttcag ctgcttgctt cataaaggct
    16381 tctgcctgtt cttgtttgcg ttcttcaaaa agtttcaata ctcgttccgc ttgctgctca
    16441 tccacttctg gttcgatacg aaattttggg aatccgtaac tgacgaacaa ctcttctact
    16501 aatggcaagt attgttgctt caaataagaa atagctcctg tactgtcgat tggcaagatg
    16561 actttacgat cttttatcac aggtacctgc gttttcaata cttgctgtgc tagtggtgta
    16621 tcgcattgct gattttccaa agcttgggcc cagtaatctt gcaagagctg ttcatcgaat
    16681 gtctggtcat ctgctaagat attcagtttg acttgtgcaa tatctttaaa agcgatagtc
    16741 agatgctgag tcaatgaccg atatagcata ataggcaaaa ttttggaaaa atgcagcgta
    16801 aattcccata aacgcgattt acgatggacc actacactat ccatttcacc agcagtaagc
    16861 agtggatgat ttttttctgc ttcctctagt tggatttgtt ccaacagttt ttcaaataaa
    16921 tctcgttttt ctgacaaaga tatacgccct ttctgatgag aaacaatgca attgatcgca
    16981 tcttatcctc ttctttttca gtacctttta gtatactcgt tttttctgag ttttacatta
    17041 aaaaattgga actgcgattc aaatcgcagt tccaatttta aaagcgaatc atcagattgt
    17101 caaaaacagc tgattcagct atttttattt tctgtgtttt aacgcttatt attcgccttg
    17161 gttcaagagg attggtaaag tattcaccaa ttcttcttta cgtacttcaa ccatttcgcc
    17221 agttttcttg attttcactt ctacgattcc atccactgct tttttaccga cagtgattct
    17281 gattggacag ccaatcaaat cagaatccgc gaatttcact cctgcgcgtt catttctgtc
    17341 atcaaccagt acttcatagc cagcttttgt catcgcttct tctagttcat tcgtcaggtt
    17401 tgtttggtat tcgtctttta gattcatttg gacgatatgc aaatcaaatg gcgcaattcc
    17461 ttttggccag ttgattcctt gttcatctga atgttgttct acgattgctg ataataaacg
    17521 acttacaccg ataccataac agcccataat cacaaatttt tctcgtccat tttcgtctag
    17581 tacagttgct cccatagatt cactgtaacg agtgccgatt ttgaagatat gtccgatttc
    17641 gattcctcga gtaaaggcaa gaacaccatt gttgtctggt gaaggatctc cttcttgtac
    17701 aaaacgaaga tcttcataag aaagtacagt gaaatcgcgt tctggattca catttttata
    17761 gtggaatcct gtttcgttcg ctccagtaat ggcattcgct aaatcttgga cataacggtc
    17821 tgcatatact tttacgtcat ctgaaacacc gactggtccg acagaaccaa actcagcacc
    17881 tagatatttt tgtgcttctt cttctgttgc ttcttctaaa aagtcagcag ataaaaagtt
    17941 tttcagtttt acgtcattga cttcatggtc tccgcgtacc aaaacaagga caggttgttc
    18001 atccgcaatg aacaatacag acttgatgat tttttgaggt tcaacagaaa agaaatctgc
    18061 tacttcgtca attgatttta cgttaggtgt agctactttc tccaattcaa gctgtgtttc
    18121 atgcgatttt tttgatacat agtagcttgt agccatctcc aagtttgcag cataatcact
    18181 ttcagtcgaa taacagatcg tatcctcccc gatttctgag atcgccatga attcttttga
    18241 gtctttcccg cccattgcgc caccgtctcc gataatcgag cgaaattcta agccacaacg
    18301 cttgaatact tcggtgtagg ctttttcgta atctttatat gtctcgtcca aactttcttc
    18361 cgttgcatgg aaagaatacg catctttcat gataaactct cttccgcgaa gcaaaccgaa
    18421 gcgaggtcgt ttttcgtcac gatatttagg ttggatttga taaagattta aaggtaattt
    18481 cttatatgaa ttgatttcat tacgcatcaa atcagtaaaa gtttcttcgt gagttggtcc
    18541 aaggatcatt tttcgatcat tgcggtcttt gaaacgatac aagtttggtc catatgtttc
    18601 gtaacgcccg gattcttccc aaagttctgc tggcaagatg gcaggcatca gcatttctac
    18661 cgctccgatt ttttcaaatt cttcccgcat aatgcgtttc agtttttcca atacacgatt
    18721 tgctaatggc agatatgaat aaatacccgc tgatacttgg cggatatatc cagctcttag
    18781 caagatttga tggcttaata cttctgcatc atttggaact tcgcgtaatg ttggaatcaa
    18841 catttttgat tgtctcattc tatatactcc tttatttcct caaaatagtt atcgtttgtt
    18901 attataccct atttgtcaac tttttctaga aaaagaatcg ttgaatatcg ttccatgtaa
    18961 ctagcaccat caacaacatt aaaaatccaa agccagctaa tgtcaatatt ccttcttttt
    19021 cttgacttaa tggtttcccg cgaatccctt caaaaatatt caagactaat ttcccgccat
    19081 ctaaggcagg aatcggaagc agattgacga ttccgagatt cattgaaaga agcgccatca
    19141 aactaataac agttgttaca ccttgatttg ctgcttctga agacaattgg tacatcatga
    19201 caggtccgcc taatttatct aaactgaaac ctgtaaatag tgatcctaag gctttgaaaa
    19261 tttccaatga accgctgaaa gcttgacgcg tccctccaat gatcttatcc ataaaacctg
    19321 tattcattgg ggcttttata ccaagttggc caactttttc gccatttgac tctacagatt
    19381 tcggtgtcac gtcgacagat tgcacctgac cttctcgttc gatcttaaag tctaatgttt
    19441 tatccggatt tttcgtaatg actgttgtca gatcattcca tgaatggatt tcttttccgt
    19501 ccacactgac tacctcatca ttttctttta agcctgcttc tgccgcagct ccattaggca
    19561 tgatctctcc tacgcgatta gtgttcgtca cttgaacacc accttgcata aatgccagaa
    19621 tgatgaataa caggattgcc aaaataaagt tattcatggg tccagcaaag ttggtcagca
    19681 tacgctgcca caatttagcc gattggaact gtacgtcttt tggcgcaatt ctgatttctg
    19741 ttccgtcgtt ttcaataatc gtcgcatcgt gatcaacagg gtaggttact acttctgttt
    19801 cgtctccatt cacataacca gtgatagtca gctcatcttc taaatcataa cggctcaatt
    19861 ccatcgggat agcatttgtc aattggattt tcttacttaa atttatcttc tctacgatgc
    19921 cgtcagaatt tagtaaaaga gaaagaggca ttcctggtgc catttctgtt tcatcatccc
    19981 cattgcctgc cattcgaaca taaccgccaa taggtaatag gcgaagcgta tatgttgtcc
    20041 cgtcttttgc ttgatgccca taaattttcg gacccatacc gatagcaaat tcgcgaacga
    20101 ggattcctga tcgtttcgca aagaagaaat gaccaaactc atgaacaatc actaatatac
    20161 caaaaacgat gataaatgtc agaatcgttt tcatagcttt tttctccttt acttgttttt
    20221 tgtgtttttt ataaaacaac gataaaacac tataatttta ccatagtata ccaaagacac
    20281 caatagtatc aatataatga aaaataaaaa cctgcgtctt ttatgaaatt cacaaagaaa
    20341 cgcaggtata cttactaaat aatgccaaat aaatgcatga taggaaatac aaacagcaaa
    20401 ctgtcgaaac ggtctaagat tccaccatgg cctggtaaga tatttcccga gtctttcaca
    20461 tcataatgac gtttgattgc agattcgacc aaatcaccaa attgtccgac tgctgaaaaa
    20521 ataatcgtca tcagaagcat gacaaacata ccatgattaa atagttcttt tgctgggtat
    20581 agcaataaat aaagaaatgc gactacaaca gcactaccaa taccaccgag cgcaccttca
    20641 atcgttttgt tgggcgaaat atcaggactt aacttatgct gaccataacg tcgaccaacc
    20701 atatatgctc cgatatcagt tgcccaaaca ataaatagac caaatatcaa aacagccaag
    20761 ctttctgttc gtgcattgac aaaattctgg aaacctattc ccacatacaa gctgacaagc
    20821 acaggaaaac ctgcttcatc aatcgtatac gtatttttag aaataactga tgttcctaaa
    20881 agaatcataa ctataagata aaataacata aatgtactta cattctctgg aagaaagaaa
    20941 aaccatcttt cttttggcaa aacaagtaac actgcaccaa cggcggataa aactccttca
    21001 aaacttaaga gtgtcaatcc tttcatccga aacagctcgt aaactcctat tactgctaag
    21061 attgctgctg taagctcaac cgctatgcct ccgatccata taatcggaat aaacaagact
    21121 agcgccacgg ctgctgtgac cacacgttgt ttcatgactg atcccctttc tcatcttctg
    21181 ttttttttac accgccgaat cgacggtctc gattttgata agaggcgatt gcttcttcaa
    21241 gatgcgcacc atcaaaatca ggccaaagcg cttttgtaaa atacagctca ctatatgcga
    21301 tctgccataa cagaaaatta ctaattcgct cttctccact tgtacggatc atcagctcag
    21361 gatcttgtaa ctctttaggc aagaaacctg tcattaaatg cttagcaatc aattcatcat
    21421 cgatttcttc tgcgtgtatt tctccttttg ctacttcttc ggcaatttct tggacagcag
    21481 tcacgatctc tgctctgctt ccataattca aagcaaaatt caataccatt ccagtattgt
    21541 tttttgtttg ctcaattgca cgtcttacag catcttgcgt atgttctggc aatacgtttt
    21601 cataacccat gacatgaact ttgacatttt ctttaatcaa ttctggtacg aacgtatcaa
    21661 agaagtcgac aggtagttgc atgagaaaac ttacttcatc ttttggtcgc ttccagtttt
    21721 cagtcgaaaa ggcataaagc gtcaacactt tcactccaag ccttgatgct ttttttgtga
    21781 ctttctttac tgtttccatg ccttctttat ggccagcaac tcgtggcaaa cgacggtttt
    21841 gcgcccaacg accattgccg tccatgatga tggcaatgtg ctgaggaatt ggtccatcgg
    21901 tattaaattg aaattcgctt ttttcttgaa tatatttgtt tttttgcgga aaaaaacgta
    21961 acattctttt tcctcctata cttaaaagat tcccactatc ttaagtatta tagcaatatc
    22021 taactgtttt tcctatgaaa tcattgtttt tttatttaaa aactgaataa ttttttcttt
    22081 ttttaatttt taaataaaag aaatataaat aaaaacagag gaagcggaat gatccgcccc
    22141 tctgttttta tgattttatt aaacttccaa taattctttt tctttatcag cagcgatctt
    22201 atctacttct ttgatgctgt tatctgtcaa tgtttgtacg tctttttcta atccgcgcaa
    22261 atcatcttcg gtaatatcac catttttttg ttgtttttta tattcatcga tcgcatcacg
    22321 acggatgtta cgaatcgcga tttttgcatt ttctgcttct tttttaacat ctttagctaa
    22381 ttcttttctg cgttcttctg tcagttgcgg gataactaag cgaatgacat ttccatcatt
    22441 ggttggactg attccgatat cacttgccat aatagctttt tcaacatctt gaagaatgct
    22501 cttgtcaaaa ggtgtgatca ttaaaacacg tgcttctgga atttggattg atgccatttg
    22561 gttcaatggt gttggcgcac cgtagtagtt cacagtaata cggtccaaaa ggctagcgtt
    22621 cgcacggcct gcgcggattt gcccaagttc acgttgaaga ttttgtgctg cttttttcat
    22681 tttttctttt gcttctgtca taattgcatc tgccattttt atttccccct tacagttgtt
    22741 ccgatatttt cgcctaagat tgcacggcga atatttccgt gttcatttaa attgaagaca
    22801 agcagtggaa tatcattatc catgcttagt gaacttgcag ttgaatccat gacttgtaat
    22861 cctttggcaa taacttccag atgagtcagt tcttcaaatt ttactgcatt tgcatctact
    22921 ttcggatcag cagaataaac accgtctaca ttgtttttag ccatcaggat aacatctgcg
    22981 ccgatttctg ccgcgcgtaa tgctgctgtt gtgtctgtcg agaagtacgg gttgccggta
    23041 ccgcctgcaa agataacgat ccgtcctttt tctaaatgac gttctgcttt acggcgaata
    23101 tatggctctg cgatttgacg catttcaatc gaagtttgca cgcgtgtcgg tacacccacg
    23161 ttttccaacg tatcctgtaa agctaaggca ttcataactg tagctaacat acccatgtaa
    23221 tcagcttgag cacgttccat gcccatttgt gctccgattt gtccgcgcca gatatttccg
    23281 ccgcccacaa cgattgccat ttcaacgccc agctcgtgaa cttctttgat ttcttggatg
    23341 atttctttga ttactggtgg tttgattcca aatcctgcgt ccccagctaa agcttctcca
    23401 ctcaatttta agactacacg ctgatatttc ggtgtgacca tgttcattcc tccaatattt
    23461 tctattgcca ttttaccata cttagatgat ttcgacactc taagactggt ttttcttgtt
    23521 ttgcttaaaa aaagggagcg cacaaaccgt gcgttcccgt ctgttattca acagaattat
    23581 tttttcactt ggctcataac ttcttctaca aagttatctt cgcgtttttc gataccttcg
    23641 ccaacttcga aacgtacgaa tgttttaaca gttgcgcctt ttgatgcaac gtatttttca
    23701 acagtcatat caggatcttt aacgaatggt tggtccacca aagcgatttc tgctttgaat
    23761 ttcttcaagc gtccttctac cattttttca acgatattcg ctggtttgcc ttcgttcaat
    23821 gcttgttctg taagaacagt tttttcatgt tctaattcag cttctggaat ttgtgattcg
    23881 tttacataac gaggattgat agctgctacg tgcatagcta cgtctcttgc aactgtttcg
    23941 tcagttgttc catctagaac agtcaatacg gcaatacgtc cgcccatatg caagtatcca
    24001 ccaaatgcag cattgtcgtc tttttctaca acttcaaagc gacggaagct gattttttct
    24061 ccgataactt gagttgcttc gatcaagtca gattcaattg tacctttatc tgttttgatt
    24121 ttcattgcag cttccatgtc tgctggtttg ttttcagcaa caagttctgc aatttctttt
    24181 actaaatctt ggaacatttc gtttttagaa acaaagtctg tttctgagtt tacttcaacg
    24241 attgctgcag tgttaccttt cacagcaact gaagccaatc cttcagctgc aatgcggtca
    24301 tttttcttcg cagcctttgc cattcctttt tcacgtaaaa gatcaactgc tttttccatg
    24361 tcgccttcta cttcaactaa tgcttttttc gcatccatca ttcctacgcc agtcatttcg
    24421 cgtagttctt ttaccatttt agctgtaacg tctgccatgt ttaactcctc ctgtgtgttt
    24481 ttctttttaa aaaaagctgc ttcaaaggag agtgaggctt gtcgcccagc ctttgaaaca
    24541 gctccatcat tcaaaattat tctgctgaag aattgtcgcc ttcaacaaca tctacgattt
    24601 cttcgattga tgttgctgtg ttttcttctg tgaaatcttc ttcaactact tgatcttcac
    24661 cttggtttcc ttcgatgaaa gcatcagcca tttttgaagt aatcaattta acggcacgaa
    24721 ttgcatcgtc gtttgaaggg attactacgt cgatttcatc tggatcgcag tttgtatcaa
    24781 ccatagctac gattgggata tttaatttgt gtgcttcttg aacagcaata cgttctttac
    24841 gtgggtcaac gatgtacatt acatctggga ttcttggcat atcagcgata ccgcctaaga
    24901 atttttcaag acgttcacgt tctttgttca aaccagcaac ttctttttta ggtagaactt
    24961 caaaagttcc atcttcttcc attgcattga tttgtttcaa acggctgata cgtttttgga
    25021 tagtatccca gtttgtcaat gttccgccta accaacgatg gttaacgaag tattgtcctg
    25081 cacgagttgc ttcttctttg attgcttctt gtgcttgttt ttttgtacct acgaataatg
    25141 ctacgccgcc ttcttcagca acgctcttca tgtaatcata agctgcatct actaatttaa
    25201 ctgttttttg caagtcaatg atgtagattc cgtttctttc tgtgaagata tatttcttca
    25261 tttttggatt ccagcgacga gtttggtgac caaagtgtac gccggcttct agtaattgtt
    25321 tcatagaaat tactgccatg tttgtttcct ccgatttggt tttatttttc ctcttcttat
    25381 cttctacctt gccggcaaac tttttcaagc acctaccgac aatccaataa gaatgtggat
    25441 ttgctgatgc ataaagcacc ctcagctatt atacagacaa aagatccgta tcgcaagagc
    25501 aaatatactt ttctgctcaa cattcaatag tttacctgaa agataaaaag aattcaagaa
    25561 aaacagtaga tttctctttg tttctttatt atcctttttc cataaaataa ttttaggtat
    25621 aaaagacgaa tattattggg caatccttct tttttttgtt atgatacatg tgaaatcttt
    25681 cgtaaaggag aaagaaaatg cgcaaagctc aaagacattt gctgattaaa caagtcattg
    25741 aagaattccc gatccgtacg caagaagaac tattaaacaa acttgggcat tatggcgtta
    25801 ccgccacgca ggcaacgatt tctcgagata tccgtgatct aaaaatcgtg aaggcacctg
    25861 atgaaaatgg cgtttcccgc ttcgtattgt ttcgcgaaaa aggaactcct gagactagga
    25921 ctgaggaaga ggatcggctg gttcaaatga ttgaagacat tgtattgaaa gtcgaacgag
    25981 tccacttttt gacgatcgtc aataccttgc cagacaatgc tcatttattt gcatctgttt
    26041 tagatgagat caaacctccc tctattgtca gtacaattgc tggattcgat acgatcatgg
    26101 tcatctcgga aaatgaggag gacgcaaaac gagtagaaga atttcttcac catccaactg
    26161 aagtatcact tttttaatca gagcacgtat tcctaatatg gaatgcgtgt ttttttattt
    26221 tcaatatttt ccttattgaa taaaccttta cactctttac aaaaatacat cattttttat
    26281 tcaaattttt caacaccttg attgaatcac aataatcatc atttatattg gatgttaaca
    26341 agagcagctt cttgctcttt gtgtatttca aaaaagaaat gaaaggaaat catatgtata
    26401 aattattaac ttctggacca ttgacgactt ctgaaacagt gaaaaatgct atgctgatcg
    26461 atcattgtac ttgggatcaa gaatacaaag aaattacaca atggataaga aaagaattat
    26521 tggatcttgc tcaagtatcg gaaggaatat acacaacggt cttaatgcaa ggtagcagct
    26581 ccttcggggt agaatcggta ttaagttctg tgatcaggcc agaagatact gtactgattt
    26641 gttcaaacgg cgcatataga caacgaatga tcaacatgtg cgaatgtctg aaactgaact
    26701 ataccgttta tgaggtatcg gaacatcaaa tcctccaagc tcatgtgatt acacagctga
    26761 ttgaagagaa tccgtctatc tccgcactag caatggtcca tagcgagact acttccggta
    26821 ttttgaataa tttggaagag attgctgctg tcacgcaaga aagagatctt ttgtttatag
    26881 tggacgcgat gtcaagcttt ggtgggatac cgatttgtgt agccgaacta gggattgatt
    26941 ttttgatttc cagctcaaac aaatgtattc aaggtgttcc aggcttttct tttgtacttg
    27001 ctaataaagc ggaactggaa aaacgaaaaa atgttagccg aagtttgtca cttgatctat
    27061 atgaccagta ccgcgtgatg gaaaacgaga atggcaaatg gcgtttcact tcccctaccc
    27121 atacggtttt ggcttttcaa caagcgctga aggaactaga ggcagaagga ggaatcgaaa
    27181 ctcgatattc acgttatctc gccaataatc atgtgctacg acaaaaaatg acagagatgg
    27241 ggttccagcc tttcattcaa gaatatcagg ggccattcat cacctctttt ctttacccta
    27301 aggactggcg atttgatttt aatcattttt atcagtattt aaagcaaaat ggatttgtga
    27361 tctatcccgg gaaaatcagc gatcatgaat gttttcgtat cggaaatatt ggcgagatct
    27421 atccggaaga tattttggaa ctgacagcaa ttatcaaaga ctataaggag aacgttaatg
    27481 attaaaactg taatttttga ttgggcagga acaactgtgg actttggctg tatggctcct
    27541 gtccacgctt ttagaaatgc ttttctagaa aaaggaatcc aactgactga caaagaaatc
    27601 cgctaaccga tgggaaaatt aaaatgggat catatccaac agcttctttc cctcccttct
    27661 gtcaaaaaac aatggatagc tatttatgga caactacctc aggaaaaaga ggtggaggaa
    27721 ttgtatcaac aatttgaaca ttatctgttt aaagatttgg tcaagcattc taccttgaaa
    27781 cccgacacat tggaaacgat cgaacggttg agaaacgctg ggatcaatat tggttccacg
    27841 aatggattta atgctcctat gatgacaatc gtagcagaaa ccgcaaaaaa agaaaggtat
    27901 tcaccagact tcatggcaac ttttgaagac gtcgaagggt atggtcgacc gtttccttat
    27961 atgatccata aaaacatgca gtacttcaaa aacaagtcgg ttgatgaagt aatcaaagtc
    28021 ggagatacgg tctcagatat ccaggaaggg aaaaatgccg gagtgttgac agtaggtgta
    28081 attgaaggta gttcgctaat ggggatttct tatgatgagt accaaaaatt agagatgggg
    28141 aaaaagatcg tttaaaacag tctgttgctc ttagattcca acaagccggc gctgatattt
    28201 gtgtaaacaa tttaaaagag ttaacagaat acattttgta cgctgacatg aatccagaat
    28261 gacttttata caaaataaga ggttgtgaaa aagctgtcct gtatcaagta ataaaaacag
    28321 ccaagcaaaa atagctcctc atatttttcg tttggttagg cttattaccg cagatgcaag
    28381 cttttgaaca ccgtttattc gaaaaaaaaa agggagctgt gacacgactt ttgtcacagt
    28441 ccccttattt gcaaacaaac agtgtttaag agacaacctc tccactaaac ggtgttcatt
    28501 cagctgactc tcggtatttg ctcaaaaaac gataaaattt gaaaagctat tttctctttt
    28561 gtttctctaa tactcggatc agaacgctga tttcacattc tctttttctt acatcttatc
    28621 tggtgcatga agtcctagca aacgaaggtc ttctttcaat aatacagtca ctgcataaac
    28681 tagagctaag cgtgcttctt tttgttcatc atcagctaaa atcttcgtat gagcatagta
    28741 tttgttgaat gcttgtgcta atttgattgc atgtttcgca atcactgacg gttcgtattt
    28801 ttccccagca gacaagaccg tttcagggta tttttgaact aatttaacca cttcccagct
    28861 ggtatcgtca ttcaatgcat agtctgctgt ttctgaaggg acaaatcctg ctttttccaa
    28921 caggctgact gcacgagcat gtgtatattg cacataaggt ccagtttctc cttcaaatcg
    28981 aacaacttct tccaggttaa agtcaaatgt attcagtcga tcgtttttca aatcgtggaa
    29041 aatgactgcc ccaaccccaa cttgtttagc tacagcatct ttgttttcca aatcagggtt
    29101 tttctcgctg atttgttctt tagcagattg gattgcttca tttaatactt cttctaataa
    29161 gacgatcttt cctttacgag ttgataattt tttaccacct tgcgtgatca aaccaaatgg
    29221 aatatggtgc atgtcgtcag accagtcaaa gcccatttcc ttcaagacag ctttcaactg
    29281 tttaaaatga tagctttgtt cattccctac tacatataga gattgtttga agtcgtaagt
    29341 acgtttacgg tacaatgcag cagctaagtc acgtgtaatg tatagtgtcg caccgtctga
    29401 cttcttaatc aacgctggat tcaggtcata agcagatagg tcaacgatct ctgcaccttt
    29461 atcctcgttc agcaaatgtt tttcttctaa aagtttgacg atttcatcca tcttgtcatt
    29521 gtagaaagct tcaccgttca acgaatcgaa acgtacttcc agcagatcat agattttatt
    29581 gaattctttc atcgattcat cacggaacca ttgccataat tgaatagcct ctttatcgcc
    29641 ttcttccaga cgtttgaacc aagcacgagc ttcttcattt aattctggtt ctgtttcagc
    29701 tacttcatgg aattggacgt ataaacgaag caattcattg attggttctg ctttaacagc
    29761 ttcttctgta ccccattttt tgtaagcgac gatcagtttt ccaaactgtg ttccccagtc
    29821 acctaaatgg ttgatgcgga ttggctgata accgattttt tccataatga aaccgatcga
    29881 attaccgata actgtcgaac gcaaatgtcc cattgagatt ggtttggcaa tattaggaga
    29941 agacatgtcg attggtactg ttccttgatt cccgatgttg ctatccccat aatgttcttt
    30001 ttctttcact actgtttgca aaactttttt gctgataagt tctttattca tgaaaaagtt
    30061 caagtaaggt ccgacaactt cgattttttc aaagttggca gaatcgattt tttctgctaa
    30121 atctgcagcg atttgctgtg gcgcttttcg gtaaactttt gctaatgaaa aggctggaaa
    30181 tgcaacatct ccgtgttcag ctgattttgg attttctagt aattgctcga cttgttccag
    30241 tgttaaatca tctttgacag cgtcatagac agcttttgcg acaagatctt tattattcat
    30301 ctttattcct cctaaagtgt tcccttgatt gttaaacaaa aaaaatctct agcgacggca
    30361 tacttagtat gccatcacta gagacgagat ttcccgcggt accactccaa ttgtcctaaa
    30421 aaaggaccag ctccatctga tatcggtaga cgaccgtctg tttaaaacag aattctccaa
    30481 gtgcgcttcg ttgtatcttc ttcattcggc ttccaccact tccgaattcg ctagccaaga
    30541 atgatacaag tactctcttg ttcaacaaat cttagtctta ttaaactttc ttgaattata
    30601 tcagaaaaaa aaacgaaagg ctagtcgttt cataaaaaaa caatccagat ggcctaaagg
    30661 agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga cttaacaaat
    30721 taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat attttctaaa
    30781 gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc tgcttctact
    30841 ttcggaagca tgcttcctgg agcgaattgc ttttcatcaa tgtattgttt catttctgaa
    30901 acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata cacattgtct
    30961 actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt ttctgaagca
    31021 aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc tacaacagga
    31081 atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt ttcgatgaca
    31141 cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca tccacgtcca
    31201 gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc ttcttcttcc
    31261 gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt ttcatccaca
    31321 ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt cagtacttcg
    31381 cccatggcgt tttgtaacca gtaaccgata gatccttctg tcattgcaac acatgtatct
    31441 aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa taggttaccg
    31501 acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat aaatttcact
    31561 aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc atccgtagac
    31621 aagatggcat tgccccctaa agcgacaact acttttcgtt tggccatttc attcgtcctt
    31681 tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt gattttccct
    31741 caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg agggataaac
    31801 aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt ttctgcttgg
    31861 tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat ttcagtgatg
    31921 ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa agctggcaag
    31981 cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc catattgatt
    32041 tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc cattgatacc
    32101 catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc gtcggtaatc
    32161 atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat ttcttcttca
    32221 ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc acctgtgact
    32281 aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt gataccttct
    32341 actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt tggatgccat
    32401 tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc ctctaccatt
    32461 ttttgactga atccacggaa ttcgattccg tcaaacatac gtcctagtac tttagctgta
    32521 tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata ttcaggatgt
    32581 gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga tgttttttca
    32641 aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg ttttttcaag
    32701 tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt aaagtctttt
    32761 tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat tctcctttag
    32821 attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta agactgccgt
    32881 caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca gcgtggacca
    32941 ccacgacctc gtgacaattc acttgaattg atttctaaca ctttgatgcc atagctacga
    33001 agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg agcgattgcc
    33061 aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc tccattacca
    33121 gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc gtgtaagtta
    33181 tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac atccatctta
    33241 ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac cattgtaaat
    33301 acggtatcca aatgcatcat tgcacggttg ttcggaattt tgattgccaa cactttttca
    33361 aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt cgcattagtt
    33421 cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc tccgccttcg
    33481 atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc aaatcttgga
    33541 tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc aaaagtcatc
    33601 ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa gtacaagttt
    33661 ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcata tagactgcta
    33721 gaacgtactt cgatatcttt tgtacgaacc ccagccatga ttttatctac catttcttgc
    33781 gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga tgcaatatga
    33841 gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc aatcgcttct
    33901 gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt cttcgcaaag
    33961 ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa cagacgatcc
    34021 ataatatctg gtgtcaaatt ttccacttct tgtccaggcc gtttcagtaa aactgtcttt
    34081 aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg cctccttctt
    34141 tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt tgtctcattc
    34201 aaaacgagac attcctcaca ttaatattcg ataattaaat aattaaacgt ttttctattt
    34261 ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata tttattcatt
    34321 gaaaaaattt ttttgaataa attaaaaaaa taaattatat tatcgttgtt agcgtttact
    34381 atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa ttattcaata
    34441 ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa acttgtttct
    34501 aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa atatagtgaa
    34561 caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt ttcaaaactc
    34621 agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat caaggaacat
    34681 actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga tcccagacaa
    34741 cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga aagtgcaact
    34801 tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg aatgtttgga
    34861 gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt ctaccttcct
    34921 gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta tatgatacaa
    34981 aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt gacctctagc
    35041 gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg cgtaccaaca
    35101 aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc agtgaatagc
    35161 ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc cgggctgtta
    35221 gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc tatgagagaa
    35281 taacgcgaac aaaaataagc agtgaccctg ataaatatca gggtcactgc ttattttcct
    35341 ccctaaaact tctgaaagat ccggcggttt tagatcactg gacaagactc aaagattttc
    35401 tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgtta gattaactag
    35461 atgaagcgtc ttgtcctcat ccgatctaga ttattcgata ttcctcgaca ataaacgatt
    35521 actcagtgag ggcaatcaga ggaacggata atgataaata agctgtaaaa aatagcaaaa
    35581 taacaataat gattaaaagt atgtaaaaaa tagggctttg acaaaaacgt gtcacagccc
    35641 tatttcgatt aaacggtgtg tacctgtcaa ctcttcggtc acaagtcata atgttcataa
    35701 acatgaggag ctgttttttg aaattgttcc ttgtgaatca gagttaaacg acaggcttac
    35761 gaactcttga ttaaacggcg ttcaaaagct tgcatacgcg gtaataagaa cagccaggtc
    35821 aaaaacatga gaagccgttt ttcctgggct gttcttatta cttgatgcag ggcagctttt
    35881 tcacaacctc tttattcaga taaaaccaag cttggatcag cattcaactg atagctagca
    35941 aaatttcttt tttgcatttc cacatgtgct gctgctccaa tcattgcagc attatctcca
    36001 caaagtcgaa gagggggaat cactagttct acctcaggga gtttagctgc caaagcatcc
    36061 tgcaatcctt cacgcaaccc ttgattggcc gctacacctc cagctataat cagttgcttg
    36121 actggataat tttgacaagc tcgaagtgtt ttagtaatca atacatcgat cacacttgct
    36181 tgaaagctag ctgctaaatc atttttgtct agatcttctc cacgctgttg tgcattatgc
    36241 accaaattga taaatgcact ttttaatccg ctaaaactga aatcataatt atcttcatgg
    36301 atcatcgctc gcggaaaatg gtaattatct tttccctgat gagctagctg atcgatttct
    36361 tttccgcttg ggtaagaaag acctaatact cttccaactt tgtcataagc ttctcctgct
    36421 gcgtcatctc ttgtctcccc aatgatttca tatgatccat cttcttgcat atagactaat
    36481 tctgtatgtc ctccgctaac aagaagtgcc atcaatggaa actggaatgg tttaaccaga
    36541 cgggctgcat agatatgccc tgccatatgg tttacaggaa taagcggcaa ttggtgtgcc
    36601 caagcaaaag ccttagctgc agaaatacca atcagcaacg agccgacaag tcctggtcca
    36661 taagtgacag cgactgccga taaatcttct gccgacacac cagcttctac cagtgcatct
    36721 tccaagcata aggtgatttg ttctacgtga tggcggctag ctacttcagg tactacgcca
    36781 ccaaaacgtt tatgactgtt tatttgagaa gcaacgatgt tagataagat ctctgttcca
    36841 tttctaacga ccgctacact cgtttcatca caacttgatt caatcgccag aatcaattct
    36901 tcattcattt catcgtctcc gtttttaact ttctgctcat aatgatcgca tcttccgtcg
    36961 gattgcgata atatgatttc cgtttaccta atatacgaaa cttttctgat tcataaagtt
    37021 ttcttgctgc ttcattagat agacgtactt ctaaaaaaac atgcagcgaa tcttttattt
    37081 gttccgtaat cagtaattgt aacaaatgcc gtgcatgccc ttttccttgt tctgaaactg
    37141 caacagcaat atttgtgatc tcgacttcat ctattacttt cgagtatcca ataaagccac
    37201 agatctggtt atcttcagct aaaagcagat aatcagagtg aggctgttgg atgtctgcca
    37261 aaaactgcat tttcgtccaa ggtgaaccat gtggataagc attttcgcta atcatccata
    37321 cgcattctgc caagtacgct tcatcaaaat ctttttttct gcaaatcaac taatctcact
    37381 cattttctaa aagttttatc atatccaacg catcttcttt tgtttcagtg taatatcttt
    37441 ttttgatcgt tgttgcttga aaccccaatt tccgataaag tctttgtgca tcttgattac
    37501 tcatacgcac ttctaatgac atcgtctcac agcgattcat tatagcaaag ttctcgattt
    37561 cgtcaataag cagcgaaccg attcgtttac gctgatatgc cggtcgaacg gcaatattcg
    37621 tgatatggca atctaaaccg aacgctcttg aaccgataaa accaatcatt cttccattat
    37681 caaagatacc tagatataga tgaggaagcg gtgacttcaa ttctgatata aaggcacttt
    37741 ttgtccatgg caattcgcca ttatagactt ctcgttcgac atccagcagc tctttgatat
    37801 cttctgtagt caattctctt agtacgtaac gacgatcgat ttgttcgact gttttttctg
    37861 tataaatcat tttatcttga aaaaagcttc tggcatacgc tctaaatttt ttcaacataa
    37921 ctttcgtctc caggtgtgtg cgtctccaac catttttctt ctgcttctac tcgttttaaa
    37981 tagcgaggaa gaaaagcttg tttctctgca actggttcaa ctaaagcacc taattgagcc
    38041 acagttacac cacttggaat atcccatgct ggaactgtat taatcatcgc actaggcaat
    38101 atttccttta tttcagagaa gaatttgtga caatcactcc cgacgaaata aatagcttca
    38161 ttcagctttt gtagttgtgt gaacaaatca gaagcagaaa tatgtacatc ttcaagtaca
    38221 gtttctaatc tattttcttt ccagcggtat gccccagcgt atacattttt tcttcgagca
    38281 tcaaacatgg gcacaataat attatccaca ccgatgcaat tagccgcgat ggttttcaga
    38341 ctagatactc ctactagctc tttatctaat gtataagcaa tcgtttttgc tgtcgttaca
    38401 cctatacgaa gccctgtata agaaccggga ccatcagaaa ccgcgattcg gtcaatgtct
    38461 tttggactta tttgaagatc tgcaaacaat tggtcgattg caggcatcag tgttacactg
    38521 tggttgcgtt tgatatttgt ttgtatttgt ccaagaattt gttcgtcttc taccacaccg
    38581 atcgccaaag tttggtttgc agtatctatt cctaatgtaa tcatatattt gatcctttct
    38641 gctatgacat tctcgccttc cattgtagca tactttttta ttctgaggat gaaaatacca
    38701 aaggcaaaac tagtacaata atacatgatt atctgctggc gggcaaattt tgccccttcc
    38761 tgaaacacaa aaaagctgcg gtatcactcc attttcccac agcttttcca tcttttattt
    38821 cgttgattct cgaataatca actctgtttc cacaataatc tttcttgaaa ccggtgcttt
    38881 ggaattactt aattgaagaa tcgtctccac tgctagctct cccatccatt cggtataaac
    38941 ttttacagta gaaagcgagg gcgttacata tttcgctaca ctgacatcat tgaagcccat
    39001 cacagaaata tcttctggta ccactaaacc tttttcttga atcgctttca gtgcgccaat
    39061 cgctaatgca tcattagctg caaaaagcgc atcaggaaca tgcggattcg tttttaaata
    39121 ttgcttcact gcttgatatc ctgactcgac agaaaaatct gcttcgataa ttggaccttc
    39181 gtcgtagcct ttttctgcca aaacttgttg aaatgccata attctgggat cttttagccg
    39241 ctgatggttt ttcttcgtat attctgttcc agcaagcata gcgatatgtt gcgctttatg
    39301 ggagacaaag tgttcaatga ctttttgaac acttgactta aagtcgacaa ctagagagtc
    39361 gattccttga gaagtgccgt cagaatctac caaaagcaag gcattttggg atcctttcat
    39421 ttctaataac tgagcttcgt cgaattttcc tagtgcgatc gttccatctg ccggaagatc
    39481 actaatggaa tcccacgttt ctttcaataa agtaacgttt gcttcttctg cctttttttc
    39541 gattcctagg cgaatagata aataataaag atcttcaagc tcttccgtat cgtcgtacca
    39601 ctggatcagg cgaagcgttt gcttagtatt tgctgcattt ttacgatgtt tcgtataatt
    39661 taagcgttct gctgcttcaa aaattttttg ctttgttgct aagccaacgg aaagatcagg
    39721 atcatagttg agaactcttg aaacagtagc aggagaaact cctgccaact gcgcaatgtc
    39781 tttaattgtt gccatttgtc tctcctcctt ttttacgttt ataaaatcgc agtaaatcgt
    39841 tcaaacgctg cctgtccttt ttcatctcgc ttgaatactc cagcgtcttc cagtacacgt
    39901 gcaaaaacct gacctacaga tttttgtacg acatcggtga ccgtatcttt cgtcaaatca
    39961 ggatgttctt tttttaattg ttctgcccac ggacgatgat attcagccat ctggttttct
    40021 tctcctaata agaaatgctc tacttctact agttctggtt tcaaacgagg tggtaaaaca
    40081 gcaagcccca ttacttcgat caacccaatg ttctcctttt tgatatgttg gacatcttta
    40141 tgtggatgaa aaatcccatc aggatgttct tctgaaacat tgttgtctcg aaggacaagg
    40201 tccaactcaa agtaattgtc ccttcttcgt gcaattggcg taatcgtatg gtgtggtgta
    40261 ccatctgctg aaaaagctct gatagatact gtttcatccg aatatgcttt ccatttttcc
    40321 aatactgagt tagctgcttc aataagcaag tttttctctg ttgattgcaa acggatcaca
    40381 gacatcggcc atttcacgac tcctgcgatg acttgcggat aatcttctag tttgataagt
    40441 ttttctatcg gtgcttttgc cataggaaat tcatgacgtc ctgcctgata atgatcatga
    40501 gaaagaatcg atcctccaac aattggtaag tcagcattcg aaccaacaaa gtaatgaggc
    40561 aagacttcag taatccgaag cagtctagca aatgtttcct ttgtgatttt catcgggcgg
    40621 tgttgttctg ataaaatgat cgaatgttca ttgtaataag cataagggga atattggaat
    40681 ccccagcttt caccgtctag attcattcga ataatccggt gattggtgcg ggctggatag
    40741 ttcaagcgac ctctatatcc ttcgttttcc atgcaaagca tgcaggtagg atagtctact
    40801 tttaccgcct cgcgttctgc tgcgatttgt tttggatctt tttctggctt agataaattg
    40861 attgtgattt ccagttcacc atactccgac tctgccggaa atttgatgtt ttttgcgatg
    40921 gctcttgttt tgatgtagtc atttttctta cttaaattaa agaaatactc agttgcttcc
    40981 tctgggcttt tcgaatagtg ctgtgcaaag aatgcattga cgactgaagg tggcggtgtg
    41041 agaaaatcca ttaattgcgc ttcaaaaatc tcttgttctg ctggcaattc tgaaagaaca
    41101 ccattttctc ttgccttagc gacaagctga tccaataagt ctacagattc ttccttaact
    41161 ggtcttactt caatgctttc tagagcatct tctcctacca tccctaaaag acgattctgt
    41221 aaatataagc ggtccatttc catccatccg ccagcttcga tcgcaagtgt ggcaaaatca
    41281 caaatcgttt gactgattga catatctcat tcccctattc ttcataacca tttggatggc
    41341 tgacatgcca atcccatgct gttttgataa tcgctttgat atctgtgtat tcaggtttcc
    41401 agcccagaat ctctctcgct ttttcacttg aagcgactaa tcggctagga tctccagctc
    41461 ttcttggtgc tatttctgct ggaatttctt ttcctgtcac ttctctagct gcttctagca
    41521 tttccttgac tgagtatcct ttgctgctgc ctaaattgaa gaagttgctt tcatttcctt
    41581 ctttcaagta ttccaaagct aaaatatgtg cagcaatcaa atcttctact tgaacataat
    41641 ctctgataca tgttccatct ggtgtatcat aatcgtctcc ataaacagcc aaggcttttc
    41701 tttgaccaag agctacttgt aaaatgattg ggacaagatg cgtttctggt gtatgatctt
    41761 ctccgataga tgcatctgct tttgctccgg ctacattgaa gtagcgcaaa gcgacatagc
    41821 gcatgccata tgcttggtca caccacttca tcattttttc catcatcaat ttactttcac
    41881 catacggatt tttaggatta gctggtgtat cttctgtgat tggagactct ttcggctctc
    41941 cataagttgc tgcagtagaa gagaatacga ttttattcac gttgaactcg tgcatgactt
    42001 caagtaagat ttgcataccg tatacgttgt tgttgaaata catcaatggt ttttcgacag
    42061 attctcctac taaagagctt gcagcaaaat ggattactcc ttcaatcggt tccttttcaa
    42121 atacggaacg tagaaattct ttatcccgga tgtctccttc ataaaaatga gcatctggat
    42181 gtactgcttg tttgtgacct gtgagcaaat tatctaccac agctacttga tacccctttt
    42241 gaactagctg gtctacagcg tgcgaaccga tataaccggc tccgcctagt actaaaattg
    42301 tcataaaaaa cactcctttg attagtaaaa ttgtgtttgt tgattctata taatttaaaa
    42361 aacgaagttt acttttatgg tgaaaacaaa caaagtaaaa tttcgtaaat tcatatggta
    42421 aatttataat aaaacattta gtaaacattt tcaagggttt tttgcaaagg tttacaaaca
    42481 aacgtaaaac tagccttttt ttctcttttg ttccataata gatataacaa ataataaatg
    42541 aggtggattc aatgaaaaaa tttgtatctg gaatattagt aggaagtctg gcaacagccg
    42601 ctgccgttgc tggtttggtt gcttctgtga aaaaaacagt gatcgatcca attgacgaaa
    42661 aagaagcaat gatcgaagaa aaccgtaaaa aagcaatgcg taaacgcgtt tctcgttaat
    42721 aattatttaa aaatacgcat gaagactttc taaaaaacag ataagtcatc atgcgtattt
    42781 ttatttgtca gtcaatataa gttgtgctat tttatctgcc tgtctcagat tccatggatc
    42841 tgtataaggt ctagctactg ctgcagttag ccaatccaca ccttcaacag gtattccata
    42901 gcaataaaag tcagactgga tttcccctga agcatcaatc acgcgattcg tacctcgctc
    42961 aacatctata gcttctgaat gataacttcc tgtattatct gaaaatgaaa aagggcgaac
    43021 aagtttgttt tccttcaaat tttttatgac aggattactt gaacgagaaa agcttgtttg
    43081 tggcaatcga gcttcaatca aatagcgact gctgatttct ttatcttgta gagaaataac
    43141 atagcggttg tgcttttgct gaatatcaaa tggcggttcg atcaaatgaa aaatacccgc
    43201 atctatcagt gctgctaatt ctttcgtccg aatgattggc ggaccgatcg ttaaaaagct
    43261 atttagatga gtaaaccatc cccatagtat ttctttgtat tccttagcag aaaaaacgtg
    43321 ccattcaata gcctgccgga ttggatcacg ccagtctttt aatgcatcaa atgttgaagc
    43381 aaatgctcct gtgcaattgc ctttttccgc ttcttttatc tgcccttcaa taaatattcg
    43441 gctagcttct gaaaagggct cattctgata ggcaagagga gtttctaaat acgaccaatc
    43501 ccatctataa gggattagtg ctggatgctt tccgagacac tcctctgaag agagggagag
    43561 aaaatcatgc tcaaaatttt tctttggaat cggcaagtga tattcttcga tgattttctt
    43621 gtaataaaac aactcaacgt cttttttcag atagtcaaaa aatgtttcgc cagtcaaaaa
    43681 tcccgactga tgccattgct ccaggttttc ttttgttagt aaccgtggcc atgccattgc
    43741 tccgccttgc ttttgatttc ttcctcgagg gtaataaggg agcccccttc ttgatccact
    43801 gtatacaatc ggttccttgc ctgatggatg atagaccagt tttccctttt cgttctcgaa
    43861 gcgccctcct cttgatactg taaacaatcc gacataatca aaaaaactta agcctagacc
    43921 tcttaaaaag acattttctt taggcggtat cttcgaaaga tctacatctg caggattaga
    43981 aggaagctga tacagtaaaa catttttctt tgcgtagtct acccacactc tttcttcttc
    44041 tgtctcatca ttttcccagt gaccgcttgc taaaacaagc tgatcgatag aatagctttg
    44101 ctgatctgtc tgtaaaagat aaccatcttt tcttttgctt acttttttta ctaaagaata
    44161 aacaaactga atagaagctg gaaattcttc ttgcaacttt gagaaaaacc agcgttgata
    44221 gagtccgtat aaacatcgag tagattgctg atctttttcc agacgattga tttcttctat
    44281 aattagttgc ttatttttgg ttaccgtctg ttcgatataa tctgtagcag gtcctttact
    44341 ccattgaaac aagttgggtc cctgtgttac caatcctcca ctggacaatg tttcatctgt
    44401 aaaaagcgtc acttgttgag aaacagaatt cattaataac tccggtggct gattcaaccg
    44461 ccaaactcga cctccaggac cattgggatc gaaaagaaaa agttcaagag aatgtctgtc
    44521 ctgattatta tggagaatcc tttctgctac acttaatcct ctaggtccgg caccaatgat
    44581 ccctattttc atttgcatgc ctccatttcg ataaattttt tcaataaaac agcatggttc
    44641 tgatgttcat tttttgcacc ataaacaaaa gtaatgactg gatgttcttt cataagttga
    44701 ctgagtttaa aaatagcttg cttcttttct tcttcgaaaa tcaattcttg ctggtatttc
    44761 tttgcaaatg aagcaaatcg ttctggtaca tggtcaaaag ttttgcgtgc ttcattacta
    44821 ggtgcaattt ctttcaacca cagatctaac tgcgcttttt cttttgaaat tcctcgtggc
    44881 cagaatctat ccacgagtat tctatagcca tcctcttttt cagcatcaag gtaaacacgt
    44941 tttaatttga tcatagtt
//
LOCUS       DAKCAA010000015        43795 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000015 DAKCAA010000000
VERSION     DAKCAA010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 43795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.015"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            6..266
                     /locus_tag="OUE31_000956"
     CDS             6..266
                     /locus_tag="OUE31_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221983.1"
                     /translation="MAYENLQLVVAGVSGDMYLAKAKDGIMDTNYRRVATDDVLSSAT
                     EWFRTNEESAVHFKGIDGNIHSLFYTKDKEKAKKILDILKES"
     gene            605..2845
                     /locus_tag="OUE31_000957"
     CDS             605..2845
                     /locus_tag="OUE31_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221984.1"
                     /translation="MSKYKFLDINVGSAFLINLDMFEAWAQSSGYNWAFSDDMIEFLS
                     RTMSWESCKVKQFLDVIAKPIYTSADDHWSGRELATLKELAEYNKNYNIPFQVSYTTD
                     DFSVIYALGKESRYLIPNRYLEIKMNSDYTNYTLGELKALRQSDSEDFSTLKNEVSTE
                     NFRISDIEELKKQQKQQLEKQKKLIEDIVNKRVDELAVQEAKIEKLRQELYEKQQSML
                     AEANKMRFELEKKVEELNTKIFYLETEIDAIEGYFGESTTFVQLRSGQKSLPEDPVVM
                     FQKVRYLDEELGRYFSMREVEGSADTMLTFEQALSSRDDLFDLFSPNKKSISMIRISK
                     SGYGYTNGQMESTNMLEKYKKYHGETLAILLRNGDNLWICWLDENKISFKDDLFYQNK
                     VTEQASETKNMVKEIDWTHTRNLEERLKDAKKQKRAVRGEFASRYILFSILQGVLDNG
                     TMMTLPEKVNVIQAINQKSPYFIASVADGWLEDTRLPSFSELIDKYSFYKETGEDRVL
                     EAEYELNPDKFENMRDYPHKQNDDIYVLYRLRGWSPTSANYTYYNSDNRSNSESGRDL
                     AYSIDLKDGIYQINLVKQGKFQKQMFSRTFVGVDSTTGENIYDYYYERETEYYIRGQK
                     AYNKSDYWGDKAKRLTANFRVYESEFINLTFLNSVFIDYVITTKRIGSYSSTYASLVP
                     MLNSMSRFLKEREEKELQYIKEIMPDFEMHEWQIALSDWKLTNKVRRITPFQAKRFLK
                     AMKFVK"
     gene            2983..3780
                     /locus_tag="OUE31_000958"
     CDS             2983..3780
                     /locus_tag="OUE31_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221985.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYGESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSKKEVRELVETPVRKKIETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYNSNRFDRLEKFCRPYTVLKTKKFNKTKRVS
                     IKLPTGQISLGEKDYLIKVGKELIIKVPERLFKENFEIRETLVWKEE"
     gene            3820..4002
                     /locus_tag="OUE31_000959"
     CDS             3820..4002
                     /locus_tag="OUE31_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221986.1"
                     /translation="MAVNRKLQVLITDDFGGAEWFDVQSIDFEEEVIVIENVYGEEYS
                     YSLEGENVEDLRLIGE"
     gene            4370..4657
                     /locus_tag="OUE31_000960"
     CDS             4370..4657
                     /locus_tag="OUE31_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221987.1"
                     /translation="MAEVKFGSKEWFEELNSMIQFPEKFTFYYNKRDNIIQVALLETK
                     GRLENTRWSMIKPSALRFHPKDLTAVVAVKEVQDSQEYYEVVKNLKDIWCK"
     gene            4748..4987
                     /locus_tag="OUE31_000961"
     CDS             4748..4987
                     /locus_tag="OUE31_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221988.1"
                     /translation="MKELEGIKKRNQERLELLNENRNRMFSYYESMRCLNKSRSEIIE
                     SSKYKQLMEERVSLIQEIETESIFPDHFPKVRFYN"
     gene            5115..5444
                     /locus_tag="OUE31_000962"
     CDS             5115..5444
                     /locus_tag="OUE31_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221989.1"
                     /translation="MKLEGSLQNRMMEGRTTNKEIVVGMGATELLYTDRNPYTVIEVK
                     SKNRILVQADGAINKATFPDQEWEYSRNPEGQILELIKTKNGWKVLKEDTHFYIGDRE
                     KYYDPSF"
     gene            5497..6345
                     /locus_tag="OUE31_000963"
     CDS             5497..6345
                     /locus_tag="OUE31_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221990.1"
                     /translation="MFSQEEIISKSQPDKNGTITMKKKIPCYRCSGSGQYKFMSMGKI
                     TYGACFKCDGDGFLVVTEKSFTPEYRAKLNALNKKRADRKIRITREKESQKNFDRYGF
                     EKGYIYVVIEENSYAIKDELHHQGATYDPLLGWFFKEKQEQYKTQKVFVEEFSVINDE
                     GIIELKLEEYSERQQEILRAKRREEGEFIGTIAQRLELDLKLTNTVTIDTQWGNVYLH
                     LFEDKNHNSLIWKTNKFLYYDEWDVGEIRKVKATIKAHDYYRDTKQTWVKNVKIQKNE
                     SEGIKV"
     gene            6342..6659
                     /locus_tag="OUE31_000964"
     CDS             6342..6659
                     /locus_tag="OUE31_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221991.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            6662..6894
                     /locus_tag="OUE31_000965"
                     /pseudo
     CDS             6662..6894
                     /locus_tag="OUE31_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6931..7410)
                     /locus_tag="OUE31_000966"
     CDS             complement(6931..7410)
                     /locus_tag="OUE31_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221992.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            7530..8867
                     /locus_tag="OUE31_000967"
     CDS             7530..8867
                     /locus_tag="OUE31_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HCU0221993.1"
                     /translation="MLIVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGDQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            8890..9417
                     /locus_tag="OUE31_000968"
     CDS             8890..9417
                     /locus_tag="OUE31_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221994.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEVEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            9404..9967
                     /locus_tag="OUE31_000969"
     CDS             9404..9967
                     /locus_tag="OUE31_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221995.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            10389..11126
                     /locus_tag="OUE31_000970"
     CDS             10389..11126
                     /locus_tag="OUE31_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221996.1"
                     /translation="MADHKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(11143..11559)
                     /locus_tag="OUE31_000971"
     CDS             complement(11143..11559)
                     /locus_tag="OUE31_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0221997.1"
                     /translation="MNKKRKLSVLITLISILTILSGILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKDKSSEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            11951..13198
                     /locus_tag="OUE31_000972"
     CDS             11951..13198
                     /locus_tag="OUE31_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HCU0221998.1"
                     /translation="MNMKKNSLGMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTDQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDGSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            13468..15858
                     /locus_tag="OUE31_000973"
     CDS             13468..15858
                     /locus_tag="OUE31_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HCU0221999.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGDGSDEFYRMFQGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKTGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGETQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGLVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            15907..17742
                     /locus_tag="OUE31_000974"
     CDS             15907..17742
                     /locus_tag="OUE31_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCU0222000.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSNLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            17811..18674
                     /locus_tag="OUE31_000975"
     CDS             17811..18674
                     /locus_tag="OUE31_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCU0222001.1"
                     /translation="MSMKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNS
                     YKEKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGEL
                     VGEILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKY
                     FTDLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVG
                     DNSHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIALIVIIKKI
                     VVKRRGMKNEE"
     gene            18664..19743
                     /locus_tag="OUE31_000976"
     CDS             18664..19743
                     /locus_tag="OUE31_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCU0222002.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIDK
                     KQTPSKEEVAKNVGQILSNNESQKVNETQESDNESFDMDEAEGKVNPYTGDVFSKNQT
                     KDFEPSTYSGAVGYIYIPKINVLELLFLGASQEHLYRGVAQMSATSLPLSGKGHQTVI
                     AGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRSDVIKNYGQNSSLTDIPDL
                     DMLTLYTCHPFPQNYDRLLVRSLRDDKAKYITPQVTVGNTAYADAIDSESVSAKPETV
                     TSSNDLFEDVDRANKELDGNNDLNIPEQASVEMQDRTFAEKASSIFTGITNKHQKMLL
                     VIWTVLGALASLKVLLLLIKEFRKA"
     gene            20082..20882
                     /locus_tag="OUE31_000977"
     CDS             20082..20882
                     /locus_tag="OUE31_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222003.1"
                     /translation="MVVISKTALDSLAKVFSSRFDSAEFVEYLSQNESGKTLIETLKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYAEDREKVKLLEGNFSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGQWNFQDDLVAFSDDG
                     YLRSYSESDYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            20991..21779
                     /locus_tag="OUE31_000978"
     CDS             20991..21779
                     /locus_tag="OUE31_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222004.1"
                     /translation="MSATTDMALEAVIKDNTGNVENIEDFSDIAINLSAWISAVGEEN
                     IEFEIKNMDDLKAKFPFIASKLSQVAEDKSWNELVSFSEKIYDITQEDECVSWEMNNQ
                     YKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADYLEKQWSKEDYAEYLKTE
                     RDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALSQYSSDE
                     EVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            22011..22880
                     /locus_tag="OUE31_000979"
     CDS             22011..22880
                     /locus_tag="OUE31_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HCU0222005.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            22900..23247
                     /locus_tag="OUE31_000980"
     CDS             22900..23247
                     /locus_tag="OUE31_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222006.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGVMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            23260..24522
                     /locus_tag="OUE31_000981"
     CDS             23260..24522
                     /locus_tag="OUE31_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222007.1"
                     /translation="MIKKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALIVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNAQN
                     FFAKLHLVDISILVLEAGAVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRHKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETEKATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            24602..25978
                     /locus_tag="OUE31_000982"
     CDS             24602..25978
                     /locus_tag="OUE31_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HCU0222008.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNKKLNGKFSVNMLNTKAKD
                     PTDAILGIKPDGTIAHFCISEMPHLLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGVQKITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMIIKHVNGSMIRAQG
                     AYISNEEIETIFNHLRNTMPEPEYVDYRAIVAESRGEGGEDEDFGGIGKAPVRKSAKR
                     NLSTPLANPSSKEPSIEKKSAFAIKLEKNKEEKVEQGAKTLEKLQAEKLEKVLRALGN
                     ADPEPQTSNNTNNKQPITSKTKPKTTDPKVSVNVTITTDNSEKKQVNGTTSPIMQKML
                     KEKKQVHK"
     gene            25975..26604
                     /locus_tag="OUE31_000983"
     CDS             25975..26604
                     /locus_tag="OUE31_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222009.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKKDKKAVLTPKQMLDHGI
                     LGVKVLEMNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKEVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            26623..27102
                     /locus_tag="OUE31_000984"
     CDS             26623..27102
                     /locus_tag="OUE31_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222010.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSMYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            27604..27657
                     /locus_tag="OUE31_000985"
                     /pseudo
     CDS             27604..27657
                     /locus_tag="OUE31_000985"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27661..28260
                     /locus_tag="OUE31_000986"
     CDS             27661..28260
                     /locus_tag="OUE31_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HCU0222011.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQVGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            28276..28752
                     /locus_tag="OUE31_000987"
     CDS             28276..28752
                     /locus_tag="OUE31_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222012.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            28769..29671
                     /locus_tag="OUE31_000988"
     CDS             28769..29671
                     /locus_tag="OUE31_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222013.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            29744..29935
                     /locus_tag="OUE31_000989"
     CDS             29744..29935
                     /locus_tag="OUE31_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222014.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            30099..30686
                     /locus_tag="OUE31_000990"
     CDS             30099..30686
                     /locus_tag="OUE31_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222015.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNDGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITNKEAKVEDVLTVRELQSLIEYRNKQITNPEYLKKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDNFKKIYLKEIEKD"
     gene            30686..31585
                     /locus_tag="OUE31_000991"
     CDS             30686..31585
                     /locus_tag="OUE31_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HCU0222016.1"
                     /translation="MWSVTLPFQPVSAPRPSARRNVSDATNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQGLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            31585..32499
                     /locus_tag="OUE31_000992"
     CDS             31585..32499
                     /locus_tag="OUE31_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222017.1"
                     /translation="MNNNEKILHVLDSFETIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKKAMELNEDRRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYEVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            32551..32766
                     /locus_tag="OUE31_000993"
     CDS             32551..32766
                     /locus_tag="OUE31_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222018.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NPVVLKQFWLNNFSYKDFIKEKANTLY"
     gene            32952..33206
                     /locus_tag="OUE31_000994"
     CDS             32952..33206
                     /locus_tag="OUE31_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222019.1"
                     /translation="MKKEELIDIFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLNSDDVNFAHDVVGIQNHIDRENKRMGDGFLPRYSSL"
     gene            33384..34427
                     /locus_tag="OUE31_000995"
     CDS             33384..34427
                     /locus_tag="OUE31_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HCU0222020.1"
                     /translation="MKKILVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTIDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNIISRQGWKIEGTGWYAMPNS
                     APNPAPAPSNEKVLNVPVIWQGNTMLCEGASLLEGLHYKGVATNQNLTSFVNYMPRAN
                     DNNPYHGYSGEWRYNVNGTYQGMMPDPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFKNGAYHVVDPVFGAKWINAGTYE
                     KSFNVTGMAVAVR"
     gene            34602..34832
                     /locus_tag="OUE31_000996"
     CDS             34602..34832
                     /locus_tag="OUE31_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222021.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEEEYKENIPENLQGS
                     ERYEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            34835..35092
                     /locus_tag="OUE31_000997"
     CDS             34835..35092
                     /locus_tag="OUE31_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222022.1"
                     /translation="MINEDFRSEQKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEEIMKREGFQADNDSKKVE"
     gene            35207..36178
                     /locus_tag="OUE31_000998"
     CDS             35207..36178
                     /locus_tag="OUE31_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222023.1"
                     /translation="MKTKGFNVKENAIGGNKIFKKDIYVWFNGKKYMTTNKRWSELVQ
                     NTVKKVMPDGYHFNYIQCSQTTESIYFSILNENRLYYFRVSSHHRKKREDNVTTFLSG
                     KYNGFKELSEAIGEYLKSNRFVRISDKHILILLLYLNNSFKLFWRDDTFYYIENGMDI
                     YSGINGTLKHYIKALLRYGVLYQEDLSNQIKISNSGKSLLAKYKKLLSPIYKGIDMEA
                     VNSETLFNLVVDEKFANEFFKSKKIESLNNLFPENAIKAYVDNNKSRLYNWFIPKRLR
                     GKIKIGDQVKVINLNHTKIVTVTELYIAEKEEITKMKPVIKILDNKE"
     gene            36188..36982
                     /locus_tag="OUE31_000999"
     CDS             36188..36982
                     /locus_tag="OUE31_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222024.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLGLAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMDKYRV"
     gene            37011..38129
                     /locus_tag="OUE31_001000"
     CDS             37011..38129
                     /locus_tag="OUE31_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222025.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKKTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETNTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGNSKDEVKGVVIDDDFEFDFD"
     gene            38162..38482
                     /locus_tag="OUE31_001001"
     CDS             38162..38482
                     /locus_tag="OUE31_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222026.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            38737..39030
                     /locus_tag="OUE31_001002"
                     /pseudo
     CDS             38737..39030
                     /locus_tag="OUE31_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321353.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            39880..40647
                     /locus_tag="OUE31_001003"
     CDS             39880..40647
                     /locus_tag="OUE31_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HCU0222027.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            40673..41218
                     /locus_tag="OUE31_001004"
     CDS             40673..41218
                     /locus_tag="OUE31_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222028.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            41219..41785
                     /locus_tag="OUE31_001005"
     CDS             41219..41785
                     /locus_tag="OUE31_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222029.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMEKENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGADDCVAYYTTAE"
     gene            41800..42048
                     /locus_tag="OUE31_001006"
     CDS             41800..42048
                     /locus_tag="OUE31_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222030.1"
                     /translation="MEGMDFLDHEDLVDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDDTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            42068..42307
                     /locus_tag="OUE31_001007"
     CDS             42068..42307
                     /locus_tag="OUE31_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222031.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEDLLRKTQRKGYPDKILKQIGYYM
                     PEERIEKEFCEVLFDSEQLLVLLTQNKLICQFENN"
     gene            42678..42959
                     /locus_tag="OUE31_001008"
     CDS             42678..42959
                     /locus_tag="OUE31_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HCU0222032.1"
                     /translation="MKVKNPTEKSRIQVGIDKNLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTKDMPVDVLDTDEKLEEWFDEA"
     gene            42949..43290
                     /locus_tag="OUE31_001009"
     CDS             42949..43290
                     /locus_tag="OUE31_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCU0222033.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     KKSDQIKRVYFPIAEWEKAGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSASDTKKL
                     NRFIEKLQRKV"
BASE COUNT        16558 a         5949 c         8955 g        12333 t
ORIGIN      
        1 aaaatatggc gtatgaaaat ttacaattag tagtagcagg agttagtggt gatatgtatc
       61 ttgcaaaagc aaaagatgga attatggaca cgaactatag aagagttgcg acagatgatg
      121 tgttaagctc agcgacagaa tggtttcgaa ctaatgaaga atctgctgtt cactttaaag
      181 gaattgatgg aaacattcat agtttgttct atacaaaaga caaagaaaaa gccaaaaaaa
      241 ttcttgatat tttgaaggaa agttagttaa ttaactaacg atataagaga aggcgagacc
      301 aagtatttgc ttggtctcta tcattttaac cactagtcaa ttaaataaat atcaaaaatg
      361 agtatggcta accacttgat cacgaacagc atcgctacaa atactgtatc agtatttgat
      421 agaatacata ttctatttta aaaaaagaaa agaaatttat tgatattata cacatcggtg
      481 tgtataataa agaggaagaa gtgattagaa ctttgagcaa ttcaatcatt gctttcgtag
      541 gagaataata gaacagctcc taagaaatcc gttgttcagt aaatttttga gtaaaggaga
      601 cgttatgagc aaatacaaat ttttagacat aaatgttggt tctgcttttt tgattaatct
      661 tgatatgttt gaagcttggg cgcaatcatc aggatataat tgggcattta gtgatgatat
      721 gatcgagttt ttaagtcgaa cgatgagttg ggaaagttgt aaggtcaagc aatttttaga
      781 tgtcattgca aaaccaatct acacatctgc tgatgatcac tggtcaggca gagagttggc
      841 aacccttaaa gaactagcag agtacaacaa aaactacaat attccgtttc aagtttctta
      901 cactacagat gatttttccg ttatttacgc attaggtaag gaaagtagat atttaatccc
      961 taataggtac ttagagataa agatgaatag cgattatacc aactatacgc taggtgaatt
     1021 aaaagctctt agacagagcg acagcgagga ttttagcacg ctcaaaaatg aagtaagcac
     1081 agagaatttt cgcatatcag atattgaaga attaaaaaaa cagcaaaaac agcaactaga
     1141 aaagcaaaaa aaattaattg aagacattgt aaataaacga gtagatgagc ttgcagtaca
     1201 agaagctaaa atagaaaaat tgcgacaaga actctatgaa aaacagcaat caatgttagc
     1261 tgaagcgaat aaaatgcgct ttgaattgga gaaaaaagta gaagagttaa atactaaaat
     1321 tttttatttg gaaactgaaa ttgatgcgat tgaaggctat tttggtgaaa gtacaacttt
     1381 tgttcagttg cgttcaggtc aaaagagctt gccggaagat ccagtggtga tgtttcaaaa
     1441 agtacgatat ctagatgaag aattaggaag atatttcagt atgcgagaag tagaaggttc
     1501 agctgatacc atgctgactt ttgagcaggc gctatcctca cgagatgatt tgtttgattt
     1561 attctcaccg aacaaaaagt caatctcaat gatacgtatt tccaaatcag gatatggcta
     1621 cactaacggt caaatggaaa gtacaaacat gctagaaaag tataaaaaat atcatggaga
     1681 aactttagca attttactga gaaacggtga taacttatgg atttgttggt tggatgaaaa
     1741 taaaatcagt ttcaaagatg atttgtttta ccaaaacaaa gtaacagagc aggcatctga
     1801 aaccaaaaat atggtaaagg agatagattg gacacatact cgtaatttag aagagcgatt
     1861 gaaagatgct aaaaagcaga agagggctgt tagaggagag tttgctagtc gttatattct
     1921 tttttcaatc ttgcaaggtg ttctagataa tggaacgatg atgaccttac cagaaaaagt
     1981 aaatgtgatc caagcaatta atcagaaaag cccatatttt attgcaagcg tagcggatgg
     2041 atggttagaa gacacacgct tgccgtcatt tagcgagttg attgataaat acagtttcta
     2101 taaagaaaca ggtgaagaca gagtattaga agcggaatat gagttgaatc ccgataaatt
     2161 tgaaaatatg agagattatc cacacaaaca aaatgatgac atttatgtgt tatacaggtt
     2221 acgtgggtgg tcgcctacat cagcaaatta tacttattac aacagtgata accgttcaaa
     2281 tagtgagagt ggacgtgact tagcatattc gattgacttg aaagacggca tttatcagat
     2341 taatttagta aaacagggaa aattccaaaa acaaatgttt tcccgaacgt ttgttggagt
     2401 tgattctact acaggcgaaa atatctatga ttactattat gaaagagaaa cagagtacta
     2461 tattcgagga caaaaagcct acaacaaaag tgactattgg ggtgacaagg cgaagcgatt
     2521 aactgcaaat tttagagtgt atgaatccga atttataaac ttaacctttc ttaatagtgt
     2581 ttttattgat tatgtaatta ctacgaaacg tattggaagt tattcaagta cctacgcatc
     2641 cttagttcca atgttaaact cgatgagccg tttcttaaaa gaaagagaag agaaagagct
     2701 acagtatatc aaagaaatta tgccagattt tgaaatgcac gaatggcaaa ttgctttatc
     2761 agattggaaa ttgacgaata aggttcgtag aataacacct tttcaagcca agcgcttttt
     2821 gaaagctatg aaatttgtta aatagaaaaa tccaccagac aagctgatgg aaactccccc
     2881 aattactaac agttgtaatt ggtgttagct tacaagttaa ttatggtgtt tagtcaatcc
     2941 caaattgtga aacggcaccg ataattggaa aggaaaaatg aaatgtctga agatttacga
     3001 gagctgaagt tacgaaagaa gcagtatgat cagtattttt ccggtttgtt gaataaacat
     3061 attgaagaag gacttgatca tgattttgga aaagatgaat attgtttgta ttgcgagcgt
     3121 tacaatgaaa aaatgtctga atatctacag ctaaagaaag agatacagaa attagagaaa
     3181 aaagtacatg cttggaagta taaagattcc atgtctggtt atggtgaatc tcaaaataag
     3241 ccaagaaaaa agaagcaagc gtatgttcta aagatggtaa atggggaaga gttaattgta
     3301 ttagcttaca gtaaaaaaga ggttcgagaa ctcgttgaaa cacctgtcag gaaaaagata
     3361 gaaacaataa atgagataga cgacagccaa tacaatagca tctatattga aacaagtcat
     3421 ggtggatata agaaattagc aactttcctt agaagttcta aagttgggat aatttctaaa
     3481 aaagacataa gtgctgttac cgatagtttt tgtactttgt ctgttcctaa agcatatttt
     3541 caatacaaca gtaatagatt tgatcgatta gagaaattct gtagaccata tactgtattg
     3601 aaaactaaaa aattcaataa aactaaaaga gtttcaatca agttaccgac tggtcaaatc
     3661 tcgctaggcg aaaaagatta tctgataaaa gtaggaaaag agttaataat caaagtgccg
     3721 gaacgcttat ttaaagaaaa ttttgagata cgtgaaacct tggtatggaa agaagaataa
     3781 tagtttggaa gacatagcag ggtataagga ggaattaaaa tggcagtaaa tagaaaattg
     3841 caggtattga ttacagacga ctttggcgga gcagagtggt ttgatgtgca gtctatagat
     3901 tttgaagaag aagtcatagt tatagaaaat gtatacggcg aagaatactc atattcgctt
     3961 gaaggagaga atgttgagga tttacggttg attggtgagt agaaaatagc agaaatatca
     4021 aaatggagat gaaatcagcg tgtatatgat tgacaagaaa acaggaaaac gtattttcag
     4081 cagtaaagac gaggtaattc gggatttgag tgaaaacttt gcaccaattg aattattttt
     4141 ccattagtta aatctagaaa ttgaaaaatt actaaaggaa cctacagaag gacgaattaa
     4201 taaagtattg aaattaatag catgtaaaga tagtcatgct tacatgcttt atccaaaatg
     4261 gtatgcagac aaaaatatag ctaaaataaa cgattatcta gctagtataa aggaacgcaa
     4321 tgcaattaat taacaataga cgaaaaatga aattaaagga gataggaaaa tggcagaagt
     4381 taaatttgga tcaaaagaat ggtttgaaga gttaaactca atgattcagt ttccagaaaa
     4441 gttcactttt tactacaaca aaagagacaa tatcattcaa gtagctttac ttgaaactaa
     4501 gggaagatta gaaaatactc gatggagtat gataaaacca tcagcactca gatttcatcc
     4561 taaagacttg acagcggttg tggcggtaaa agaggttcaa gactcgcaag aatactatga
     4621 agtagtaaaa aatctgaagg atatctggtg taaataattc taaattgacc agttatttgg
     4681 tcaaaaatag tatgtgatta tttcatccaa tatggcatca taattggtat gaaaggggat
     4741 aaattatttg aaagaactag aaggtattaa gaaaagaaat caggaaagat tggaactgtt
     4801 aaatgaaaat agaaatagga tgtttagtta ctatgaatcc atgaggtgtt taaataaatc
     4861 tagaagtgaa attatagaat catcaaagta taaacaattg atggaagaga gagtttctct
     4921 cattcaagaa atagaaacag agtctatttt tccagatcat tttcctaaag tccgatttta
     4981 taattaaaca ttaacaaatg aaacgatgct aaataggcat cgttttttat ctatttgtta
     5041 aatttattta tttacaaaat gtgtatcggt gtgtataata tatttgtaga taagttaaga
     5101 aaggatgatc tgaaatgaaa ttagaaggta gcttacaaaa cagaatgatg gaaggcagaa
     5161 caacaaataa ggagattgta gttggtatgg gagcaaccga gcttctatat accgacagaa
     5221 atccttatac agtgattgaa gtaaaaagca aaaacagaat tttggttcaa gcggatgggg
     5281 caatcaataa agctactttt ccagatcaag agtgggaata cagcagaaat cctgaaggtc
     5341 aaatattgga attaattaag acaaaaaatg gatggaaagt gcttaaagaa gatactcatt
     5401 tttatatagg tgatagagaa aaatactacg atcctagttt ttaaacaaac tgaagatgag
     5461 cgaggtttta tcctcgctca gaaaggagta tgaaggatgt tcagtcaaga agaaatcatc
     5521 agcaaatcgc aaccggataa aaatggaact ataaccatga agaaaaaaat tccttgctat
     5581 cgttgtagcg gatcaggtca gtacaagttt atgtctatgg ggaaaattac ctatggcgca
     5641 tgctttaagt gcgatggtga cggatttctt gttgtaactg aaaaatcatt tacgccagaa
     5701 tatagagcta agctaaatgc tttaaataaa aaaagggctg atcgaaaaat aaggatcaca
     5761 agagagaaag aatctcagaa aaattttgat cgttatggtt ttgaaaaggg ttatatttac
     5821 gtggttatag aggaaaatag ctatgcgatc aaagatgaac tgcatcatca aggagctact
     5881 tatgatcctt tattaggttg gtttttcaaa gaaaaacaag aacaatacaa aactcaaaaa
     5941 gtttttgtag aagaattttc cgtaatcaat gatgaaggaa ttattgaatt gaagctagaa
     6001 gaatacagcg aaagacaaca ggagatttta agggcgaagc gtagagaaga gggtgagttt
     6061 attggtacaa tcgctcaacg attggaattg gatttgaagc ttaccaatac cgtcaccata
     6121 gatacacaat ggggcaatgt ttatctgcat ttatttgaag ataaaaacca taattcattg
     6181 atttggaaga caaataaatt tctttattat gatgaatggg atgttggaga aataaggaaa
     6241 gttaaagcga caataaaagc gcatgactac tacagagata ccaagcagac ttgggttaaa
     6301 aatgttaaaa ttcaaaaaaa tgagtcagaa gggataaaag tatgaaaaga gaggaataca
     6361 aacaaagatt aaacgaactg cttgaagagg acgaaacgtt aactcatggt tcgcctgatg
     6421 aaattctata catgattgat aatatggtga tctttggtgg atatgaactt ggtaataggt
     6481 cagttgatca taatatttta gaatttgatg atgtatcatg ggaagaaatt cttgattggg
     6541 gaattttggc ggtacctgaa actaaaacct atattagtga cactatggtt cctttttttg
     6601 aggaattgga ttataaaaga cttcccaaaa atgaaaatca tatactggga ggaaactaac
     6661 aatgttaagt gacttattta ttttactgat ctatctaggt gtaagtgaaa ttattgcgta
     6721 ttttttgttt gtcattgcta attatggtat ttccagtgca atcgttcaaa ggtttagatt
     6781 accagtaagt gaactaaaaa aaagatgaga ttatcagcat atcttttaat gtttttgaat
     6841 gtggtcacgt taatctttgt agtaatcggt gtgactttcg atttaatgga atagagggaa
     6901 atctataatg gaaaaaagag taatgattgt ttaatcatca ctcttttttt gtagggaaat
     6961 tgaaatatgt ggagcttgta ttggtttagt taggattgct tggctataag gagctagttc
     7021 tttatcaaaa ccatcaaagt aggttttcag tagcgattta actgatcgct catcttgttt
     7081 gatttggata atttcagcat ccaaatcggt tgtgagatca ggagcttttg atgcgattac
     7141 ctgatttttt ttatcttcca actctcttag gctgtttaac aagttgtaaa aagaatcatt
     7201 ttgattgttc attccaacgt gagttgcaat tttaacagaa gtttcgtccg tattgtcatc
     7261 aaaagaactc attggaatat caagtagtaa cgaggatgtt tcttttactg actttttctt
     7321 tacagcattt tttgtttttc catctttttt gctctttact cgagatgttt ttggagctag
     7381 tttaggtaaa tcacttgttt tatcagtcat ttattagctt ttcctttcta ttaatttatg
     7441 ttattatatt atcataataa cataaaaaag tacacttttt gggggcgtag ttattgaaaa
     7501 aatctaagag aaagattgcc acgttgctta tgttaattgt gcaatttaca ggaattgcaa
     7561 tgagtgtaat cacaataaat ccgcaagtga tacatgctga tgggatagct acttatgatg
     7621 cacaatttaa ctgtactact gaaggtagtg ggtcaggaac agatagcgat ggaaacgata
     7681 ctggaagtgg cgctgtaaca ggtgatgtag ccaaaaatat tgaagatatt tacaaataca
     7741 tgaatggaga atatggctta tcaggtgcta gtattgcagg tattttaggt aactggaaac
     7801 aagaatcagg tattgatcct cgagcagtag aagggtatta cggagatgga cagagagaag
     7861 ttgacttcat caaacaattt actgatggtc tgatgggtat tggctatggt caatggacag
     7921 ctgggcgaca tacagcacta gttgattggt ctaagaaaaa taatggcggt tcttggtgga
     7981 ctacagaagc ccaattggac tttatgttca aaggtgatgg gggattcgta ggaatattaa
     8041 aagattatgc tttaaatgct tctgatgatg tcgtagaaaa tgcagtaact tttcataaaa
     8101 actgggaaat ttcagctgat tccgaatcag ctgtaatagc tgtacgtggt gaaaatgcaa
     8161 aagaaatctg gaagtacatg aaaagcaagg gtatggacgg tgcaaaagat gaaagtaaga
     8221 tcaataaaat atccggaggt tcaagtaccg gagatggatc gaataattca tcaagttcag
     8281 catcaggaac agtagaagat gcctgtgcaa ctacggatga cgctaattct ggttctggat
     8341 caattgggaa agaaggaaaa attaacggta aaaaaggtca agtaatagcg aatatgactt
     8401 atgaagaagc tttgaaaaaa tatgggaaag cgatcacgct accaaaattc aaagaaccag
     8461 attggtcaac ttcacctttt aacggaatat atcaaggtca gtgtacagag ttgacgtggg
     8521 cttatatgag ccaattatac gatggggatc aaccgactac tggaaatggt ggctatgtat
     8581 gggaaagcta caaatcggca ggagcaaaaa taacgaacaa accaatcgta ggttatgggt
     8641 ttagtgcttc ggatggatgg ttatgggctg ttggagatgc agggcatact ggtgtagtta
     8701 tagcggtgtt tgaagatgga tcatttctat gtgctaactt taatgttcca ccaacccaag
     8761 ctccaacaag gggagtttcg gtaacgttga ttgatggagt ggacggatca gataatgtgc
     8821 atttctttag tggtgtagga aaagctaaat ttgaaatcga aaaataaatt ggaatgaagg
     8881 acgatataga tgaatagtaa agtgaaagat acaattatca tttctttgct ttctggtatg
     8941 ttattagcac tgcttgttgg aatcctattc ttcaataagc agaatcagga catagaagtt
     9001 gaaaaacaca gtgtgcatat tgaagataag ctgacattct ttaaagaggt taaaccaaat
     9061 gaggtggatg gattacggaa agatttagaa aatgatattc aagaaatgtt gaatggatca
     9121 gttcaaaata agtttgcaga tcaatcaggt gaagaatttt tgagaaaact atttattgta
     9181 acaggtaaac caccaattac tgataagagt agtgagaaag aaaaaatcga gtactataag
     9241 ccttttactt ttaagctaac aaactttgga attaagacat ctagtagtgg gttgtatgaa
     9301 gcattgaccg attttgaagt tcaatacaat ggaaaaaaag tgtatgatac cacattaacc
     9361 atcacactaa ataatgataa gaaagtgact gggggtgctt tttatgcaaa atcatgaaat
     9421 cactactgct aaaaaggcga tcggaatact ttccataatt gtgatccttt gttgtgtggt
     9481 actatttcaa aagaaaaatg cttatgataa taatgtcaaa gaattggaag accttaaaag
     9541 taaacaaatc gaagtagtca agaataacca gaaagtgaaa gctatgcagg aagctcaata
     9601 caaagaattg ggaaatgctg aaattaagga acaaagtagg aaattcttta atttatttta
     9661 caactggaat tcatgggaaa aatatacgaa gaatatgaag gaaatacaaa aagaatttcc
     9721 tcagatagta aagtctagtc ctgttgatat ttctggcacg atggtaggca ctggtaatag
     9781 tccaatatct agctatactg ctgattacta tacaacaaat caaaaaggta aaatggttga
     9841 attgattaca cagacaagaa atactccaac aacagcaaca acaacaattt ggcgtggagt
     9901 aacaagcata ggagaaaatc aattgtttta tttggaggat ttagatagct atgtaagagc
     9961 agagtaaaat aaaaaaagag ctaacggtac caacgttagc tctttgtgct gacgatgata
    10021 acaaaaccta ccgaaaaagg attgtttcat cacaaacaca aacagaaaag aattgataaa
    10081 aaacccgaac ctcagaattt ttattaatca attcatttag attataataa attgagctga
    10141 acattacaat acgtatatgt tgtaaaacgt aaaaaaagtc aaaagtaatt actttcttaa
    10201 aaagtcaaat aaaactatta aagacaatat atatggttta tttgacataa gaaaatggtc
    10261 tagatgataa ttgtaatata gaattgtaga cttaaataaa gcataaaata ccttttatga
    10321 taaggtatag ctcttaattt taagcagttt tagatataag attgaaagta aagtggggga
    10381 gaataataat ggcagatcat aaattagaaa agttattaga agaaacgtgg aatccaaaag
    10441 aatttagtga attttttatg gagaattttg aaactgactt agcagtgatt gttaaagatg
    10501 ctcttagaga gcaagggtat cctgaaactg caaactatat aaacattaat tttactttgt
    10561 atactgaaaa taaaggaact tgggattttt gggctacttt agcaaataag gagttaagtg
    10621 ataaatcaga cacaggaatt cgtaactttt ttgaatcaaa cagagatgat tatatgtatg
    10681 ctaacaatca aaataaattg aactttagag tagagtttga tgaaacacct gaagaattta
    10741 tagaaagaca accgcctaaa gaaaatgtag caaaggtatt ggaagatcgt tggaattcag
    10801 atgaaatagt ttcaacaatt agcgaactag gcggacaata tgaaccgcta gtagaagcgg
    10861 ttagagaaga gctaagactg aataagtttc ctgatgttca aaatattgat gtttctcaaa
    10921 ttgaaataaa cgtcaagatt acgaataaac ttgattatgg tagttgggca gatatagcat
    10981 tagaaaaata catctactca acgttaaaag agtttatcga aaatagaatg gatatcatgt
    11041 atctacagca tccacagtat ttaaactttg gtgttgaaat agctacacct cttgaagaat
    11101 ggaaaatgga gcaagggctt gactagcctt tgctccattt ttttatttta caaatgaata
    11161 cagttcgtcg tttttaccaa gaatgattgt ttgcccaact ttgagattgt caggtgatcc
    11221 ttcagcggtt tgtaaggaga acgttccatt gaacttatcg gataccgtta taggtagctt
    11281 taattctgat ccttcctcat ctttgagaat tgctgttttt cgttcatcaa aataaacagt
    11341 ctttattaaa taatttttcg tagtgatctc agaagatttg tctttttttg tagtagtacc
    11401 agtttcttta gaattagagg tattttctac gactattcca tctttggcat ttgagcttgt
    11461 gtttatttga ttgaatattt tcagcgacaa gataccgcta agaatagtca atatagaaat
    11521 aagtgtaatt aatactgata atttcctttt tttgttcatt tttcttaact tccttttttg
    11581 ttttgattag ttagatattc cttatctaac aagcattttt aggctattaa atgaagataa
    11641 accccaaaaa aatattgcaa ttatgacagt gcaatggtac tattattata caataaattt
    11701 tgcgaaaggg gtaggtctaa atcgcaaaca aaaagaaatt gaacctagac aaatacaact
    11761 tgtataccgc aagggaagca agtttgattt tgggtaaagg tagaaattat gttacaaaca
    11821 taattaacta ttatccaaat cgtttgccta aaggttcgtt caagaaagtg ggtgacaaaa
    11881 cctatattat aacggaagaa ggaatagaag cattgcgatc acaaacagaa aataaaaaca
    11941 aaaagaagga atgaatatga agaaaaattc gcttggtatg gttttatttg catcagctgt
    12001 acttgcgggg ttatcagtac cagtaacctc acatgctgat gaatggactg caaacacacc
    12061 ggatcaaatc caaattacaa caggacaatc aagttatgcg ttcaaaaaag gagatactat
    12121 ttggtcaact gtagagaagc ttaaaagctt aggttacaag actactgttg ctgagtttgc
    12181 cgaattgaac aatgttgatt tggcaaaagg agaacaacga actatcccga ttggacgaac
    12241 tttcaacatc agcaaagata cattaacagt taaggaagca gatggcgaag tagttagtca
    12301 aactgttcaa aaggataaac ctgatcctgt tgaaaatacg gatcaagaga acaaaaaatc
    12361 cgagactaca aaagaatcgg aaccaacagc aaacacttct gataagacag aaacaagtgc
    12421 ttcaagtgtt gatggagcaa gttcatctaa tacaaataat tctacaagtg agaaagaagc
    12481 atcacaggga acaagtgaaa gtagcactac ggaagctgat actggaacat caacaaataa
    12541 ctcacaatca acatcaaatg atgcaaatga atcaaccagt acatcttcta gtgatcaatc
    12601 acaaacaggt tcgagtgatg aaactgacgg ttctacttca ccaagtaaac ccgaacaacc
    12661 aactaatgtt gtgctaggcg ttccatttat tagtcaaggt aacacaatgc tttgcgaagg
    12721 aacatctttg ctagaagcgt tacattataa aggtgttgca acaaatcaag atttaatgac
    12781 ttttgttaaa tcaatgccac tatctcctga taataatcca aataatggtt tttctggtga
    12841 atggagacac aatgtggatg gaacttatca aggtatgaat ccggctcctg tagtttcatg
    12901 gggtgttgct aatggcggaa atgttgtaga tatttctggt tcatcggtac aaggattaaa
    12961 agatgagatt gtaaatggaa atcctgtagt agcatgggta acttatgcct ttgaacctgc
    13021 tcaacataaa tcaatgtttt ggggcgatgc tatttggaat cgacatgtag tagccgttga
    13081 tggatttaaa gacggttttt accatgttgt cgatcctgtg tttggggcaa gttggattaa
    13141 tgcaggatca tttgaaacag catataacgt atctcaatta gcggtttcgg tacgttaata
    13201 aaagagatcg tttatatact aagtagttaa gtatagtctt tatttgtcct taattaacta
    13261 cttagaaaac ttgttgctca tggtgggtag aactaaaagg ggtgatgcta tgaataatag
    13321 agcgttgaaa catcttgctt tcaacgaaaa aagtgattaa taggtgtggt gattttaact
    13381 taggaatggg cgcgaaggtc attaccacac cgacatatcg tggctcattt tcttcgccta
    13441 acttgtataa agaaggagta acgagagatg aagcatgaaa aaacgataat tttaaaatca
    13501 aaaataattt attgttttgc gactttagta atggtgttat ctacgcttat aatgcctttt
    13561 tcagcaataa gagctgaagc agatgtcaca aaaccgacaa gtgcaaaatt tacagaaact
    13621 ggcgtaaaaa cagacggtta tattagggtt aatatgccga atcatccaaa tgaatggatg
    13681 atttcaagtc aatttaaaga ttctcatgga aatattggat attgtatgga ttcagaattg
    13741 ccatccccaa caggaagtgg agccggaagc ttgaagtaca agggagatgg cagtgatgag
    13801 ttctatcgta tgtttcaagg tggttttcca tcaaaaacag caaaggaact gggtgcagga
    13861 aatgatacag aagcatggta tgcaacacaa ttagtttcat gggttttagc cggaaacttt
    13921 aaagtttcac agattgtatg gtcacatcca aaccataccg ccgcagaaac agctcgtgta
    13981 aaaaaagcat ttgaaaaaat ttatgactat gctaagaatg gaaaagatac gcccaacact
    14041 gagttttcta tcacagcttc taagacagct gacgaaggaa aatatcacac tttcacatat
    14101 aaaacagcat caaataagac tggtaatgcg aagctcactt ttacatcagc aaaacctgct
    14161 ggtatgaaga tttatgatgc agatggtaaa gaaattacta acaacactgt gaaattaaat
    14221 tcaagtttta ctattaaagt acctgtgact acaccaagtg gtactttgtc atttaaaggt
    14281 actgctaatg ttagcacaac caatcctttt acttttgatg gacgaggtgt gtatcaagat
    14341 gccgtagtta tgatcactac ttcagaaaca aaggactcta aatctttgag tgctaaatgg
    14401 acaagagctg ttggtcaggt aacagttaag aaagttgatc aagatggaaa tgctttaaaa
    14461 ggagcggagt ttactctaac tgacaataac aatgctaaat ctgttaagac aaccggagat
    14521 gatgggttag ctacgtttga tttgcaacaa ggcttaacat acagcttaga agaaacaaaa
    14581 gttcctgaag gttatcaagg ttcatttaaa aaggatggta ttactgttaa taccgatgga
    14641 caagaattta gttacactgc tacgaacaca attaaaaaag gtaaagtaaa agttaaaaag
    14701 gttgaccaag atggaaaacc attagctaat gctgaattta ccttgacgga tgattcatcc
    14761 caaacacaag cagaaaaaac agatgaaaac ggacttgcaa gcttcgatat tgtagcaaac
    14821 aagacctaca gccttgaaga gaccggagta ccaactggtt atacaggcgt attcaagcaa
    14881 gaaggaatta ccgttaaaga tgatggacaa acttttgaat atacagctac aaacactttg
    14941 aaaacaggtt tagtaaaagt tcataaagtc gatcaagatg gaaaaccttt ggcaaatgca
    15001 gagttcactt taaccgatga aaaaggtgaa acacaagtag aaaaaacaga tgaaaatgga
    15061 cttgcaagct tcaatattgt agcaaacaag acgtatagcc tagaagaaac cggagtacca
    15121 gtaggttaca caggtgcatt taagcaagag ggtatcaccg ttaaagacga tgggcaaact
    15181 tttgaatata cagctacaaa taatttgaaa aaaggtttag taaaagttca taaagtcgat
    15241 caagatggaa aacctttagc agatgcagaa ttcaccttaa cggatgaaaa aggtgtaaaa
    15301 gaagttaaaa agacggatgc aactggtctg gctacgttca acattattgc gaacaaaact
    15361 tataacttag aagaaacaaa agtaccaaca ggttacacag gcgcattcaa acaagaagga
    15421 attaccgtca aagatgatgg acaagtcttt gaatatactg ctaaaaacac tttgaaaaaa
    15481 ggtgtgatca aagttcataa agtggatgat caagggaaag cattagcaaa cgcagaattc
    15541 actttgacag acgacaaagg tgtaaaagtt gtacaaaaaa cggacagcaa tggcttggca
    15601 acatttaata ttgttgccaa caaaacgtac aaaatcgaag aaacacaaaa ccctaatggt
    15661 tatacaggga aatggtctaa agaaggcatc accgttgctg acgatggaca aacctttgaa
    15721 tatacagtaa ttaatcacct tgtacctgaa acagtaagaa caggcggaat cggtacatca
    15781 gccttccttc ttgtatttct aattgcagga ttgagtatgg tgctactgta ttatcgagaa
    15841 cagcacaaag caaaataaaa aagtgttact ggaaaagaag taaatatgaa aaaagaaggc
    15901 tgacgtatga aatcaaaaaa aattttttca aatttaatgc tatttggtac tttgctagga
    15961 gtgggattgg gcgcaagctc aatctcttct aaccttggac taggggggca agtagcatat
    16021 gcacaacaaa actataatta tcaaggaact ggaacgattc atatccataa agtaacaaat
    16081 actaatgggg atgggaaccc tgtctcagat attgataaca aagggaaaga aatagcttta
    16141 ccaaatggtg taaaacctct tgaaggcgtt gagttctctt atgtgaaact tactaaagat
    16201 gaagctaaat ccttgggatg gacggatagt gatactacaa aaggtcaaca tattgatgat
    16261 gctaaagcac gattattact aaacaaaaaa tacagtgaag taagtagaat gaagactgat
    16321 tcacaaggga atatagacat acctatacaa gtaaatacag acgatttaac agataacttg
    16381 tatttgattg ttgaaacagg aacagtcaaa ggtgtagttg aagaagcgta tcctatgatt
    16441 gttaacgtac ctgaactaaa cggatcagat gatcaatact ttaattatga tgtacatgtc
    16501 tatcctaaaa actatttcca attaaactca gcagagcttg ataaaaaaga cgaagatgga
    16561 aaggctcttg ccggaactgt ttttgaattg cgaaaagatg atggatctga tcaggttgtt
    16621 ggaacttata aaacagacag cacaggtaaa ttaactgtag atggtttgga attaggtgac
    16681 tattatttcc tagaaaccga tttgggaaca gatgctaata aaacaaccta tttactagat
    16741 ggtaaaaaat tcaaatttag cgttaaacgt ggggagactg ctaaagtagt tcttgatgtt
    16801 accaactaca aacgacctgt aattactaag gtaattgata aagaaaccgt tgatactggc
    16861 gaagatgttc aatatacatt gaaaccatca attcctggta atattggtaa ttacgaaaaa
    16921 tatgttgtca aagatgttct aggtgcagag ttaacttatg attcatcaga agtgatcgaa
    16981 ggaatgactt tagatactga ttacagtatc gaacgtgacg gacaaacgac aaactatgtc
    17041 tttactgaat caggtatgga taagcttcag aaacaatttg atgcagggga tcgcttcttt
    17101 acaattttga tgaacgctca tactaatagt aaagctaaaa tggatacacc acttaagaat
    17161 gatgtttcaa cgatctacaa caatggatat gaacccgaag acgaaacacc agttgatcac
    17221 gcttatacaa tcattggtga tcaccaattc attaaaacag atggagatac aagcaaagca
    17281 ttgagtggag caaaatttgt agtgaagaac aaaattgatc cgaataaagt tacttaccta
    17341 aaacaagatc caacaacgaa agctgttact tggattgcag ataaatctaa agctactgaa
    17401 ttcgtttccg gatcagatgg taagttccaa attgaaggct tgcaatatac ctatgatgta
    17461 gattttgata aacaaggtaa tccaacaatc acagataaaa aaatcaatga ttatgctctt
    17521 gaagaagttg ttgctccttc aggatataca ccaactagaa atgatgttcc atttgtggta
    17581 tcgaatgatg atgcttctag cgaagtaaca gacatcaaga accttaaaac acctgaaaca
    17641 gttcgtacag gtggaattgg aacagtagta tttctagtgg ttgcaggtgt ggcaggaaca
    17701 gggctatatg ttgtctacaa acgagaacaa cacaaagctt aatgaaataa aattccctag
    17761 agtgtttttg gctctagggt ttctttttaa aaagtgtgtg aaaagtaggt atgagcatga
    17821 aaaagaagaa tatcaagttg atcatcttaa aaattgggat gttgctatgt ttaggagtag
    17881 gtctatatcc tgtaattact caggcttata cctactacca aactcaacaa acactaaact
    17941 cctataagga aaaatatgat gaagcttctg aaaaggagaa tgaagaagtc ttcaagagat
    18001 attcagaagt taataggaaa cgaaaagaca cagaacaaac ctcagtcacg attcctgaag
    18061 ataataacaa tattccgtca aatggaaatc ttcagaagga taaattaggt gaattagtgg
    18121 gtgaaattct tataccaaag attaatgtgg atttgccaat ttatgatggt gtaaacgatt
    18181 ttcaactatc agcaggagca ggaatattaa ccggaactga ttatccaact ggtgggattg
    18241 gaaaccattc tgttatatca gctcattcag gcattcctaa taaaaaatat tttacagatt
    18301 tagagttgct caaacttggt gataaatttt ttattgatat ttcagggaaa aagcttgctt
    18361 atcaagtaga tcggataaaa acaatcctac caaccgaatt tgaggatttg cttcctgtgg
    18421 caggaaaaga ttatgtaaca cttatgacat gtacacctgt tggagataat tctcataggt
    18481 tactcgttag aggggttagc ataccttacc aaaaaagtat tgttgagaaa gaaaagaaga
    18541 aagaagattt aaaggtaaag gcgcagatga actggtatcc tatcgtagtt gtaggggttt
    18601 tattaataat agctttaata gtcattatta aaaaaatagt ggtaaagaga agagggatga
    18661 aaaatgaaga ataaaatact actttttttg actcttattt gcactttggt tttaacaatt
    18721 tatcctgcaa atcagctcta tcatcaattt aaaacgaaag agaatgtggc ggaaatccaa
    18781 gagaaaattg ataagaagca aactccttca aaagaagaag tagcaaaaaa tgtcggacaa
    18841 atactatcga ataacgagag ccaaaaagta aacgaaacac aggagtcaga taacgaatca
    18901 tttgatatgg atgaagcaga aggaaaagtc aatccatata caggagatgt tttttccaag
    18961 aaccaaacga aagattttga accatctacc tattcaggag cggttggcta tatatatatt
    19021 ccaaagatca atgtgctaga gcttttgttt ctaggcgctt cacaggaaca tttatatcga
    19081 ggtgtggcgc aaatgagtgc tactagccta ccgttatcag gtaaagggca tcaaacagta
    19141 atagcaggac atcgtggagg ttatacgtca ccacaatttc tttacgttga tcagttagta
    19201 gcaggagatc acatttatat agattatctc ggcgaaaaag cagtctatac agtttttcga
    19261 tcagatgtta ttaaaaatta cggtcagaat tcatcgctga ctgatattcc tgatttggat
    19321 atgttaacac tgtatacttg tcaccctttt cctcaaaact atgatcgttt attagtcaga
    19381 agcctaagag atgataaagc aaaatacatc acgccacaag taacagttgg gaataccgca
    19441 tatgctgatg ccattgatag tgaatccgtt tcagctaagc cagaaactgt tacatcttct
    19501 aatgatttat ttgaggatgt tgatcgtgca aacaaggaat tagatggaaa taatgatctt
    19561 aatattccgg aacaagctag cgtagagatg caagacagaa cgtttgctga aaaggcaagt
    19621 tcaatattta caggaattac caataaacat cagaaaatgc ttttagtcat ttggactgta
    19681 ttaggagcat tagcaagtct aaaggttctt cttcttttaa tcaaagaatt tagaaaagca
    19741 taatgaagat tataaaaatt gatagagtac agtaaaaagg gattgatact attattgatc
    19801 tcttttttat tttgaataga gctagattca cttttaaata aaatcaaagc tgatcttaat
    19861 tccaaagaaa aagtcaagaa aaaaataaaa caaatttttt aatcagaata tttatcagaa
    19921 aattattaga aaagataatc ttaaaagctt aatttaatag ggttattggt tgtatttaaa
    19981 aataatgtat ggaaaagcta taaatcaata gataagatgc agaaaatctt atttgtgaat
    20041 gaaaaacaag tcatcgtaaa atattaatag gaggtgtagt aatggtggta atatcaaaaa
    20101 cagcattaga ctcattagct aaagtattta gtagcagatt tgatagtgca gaatttgttg
    20161 aatatctaag ccaaaacgaa agtggaaaaa cattgatcga aacactgaaa aaagactatt
    20221 tgaatgaaaa cgactttccg acatggacga atattgaaga tgctacatgg gatgtagtgt
    20281 gtacgatata ttctccatgg gtaacgatcg ctgattttgt tttagataaa atcggagggg
    20341 atacttatcc tgatgccaaa tctcttgcta caagtgattt taaaacgttt tatggctatc
    20401 taataggtct aataggcaat ggcatagatt tgaaagttac gccaaaacaa acacctgaag
    20461 aaattgaaaa agaaaaagga gaggttcaaa tggcttatgc agaggacaga gaaaaagtaa
    20521 aattattgga aggcaatttt tctgaagaag aacttggaaa aatggtgcaa gaaatcaacg
    20581 aagacagcaa ctattttcct gaattgaagg tatatcaaaa tgacgaagat ttcttcaatg
    20641 aaatgtttag taatagtcca tgggaagcag taagtaaaac aaatttagga caatggaact
    20701 tccaagatga tctagttgca tttagtgatg atggctattt aagatcatat tcagaaagtg
    20761 attatagagc tgaattaaaa acgtatgaaa cggatattct aatgagctat ttaaacctat
    20821 tagagagtgg tcagggagag ttaagagata aagttgaaga actattaaaa gaagaacttt
    20881 agggatcatt tcaacataaa cacaagcaga aaactaccaa acaaaacgta ccatgcaaaa
    20941 agtcggttaa accggctttt tgctctatta tgagaagagg agatgaaacc atgagtgcaa
    21001 caacagatat ggctttagaa gcagtaataa aagataatac aggaaatgtc gagaatatag
    21061 aagactttag cgatattgca attaatcttt cagcatggat ttcagctgta ggagaagaaa
    21121 atatcgaatt tgagatcaag aatatggatg acttaaaagc aaaatttcct tttatcgcat
    21181 cgaaactaag tcaagttgcc gaggataaat cgtggaatga attagttagt ttttccgaaa
    21241 aaatttatga tattacgcaa gaagatgagt gtgtttcatg ggaaatgaat aatcaataca
    21301 agaaaattga cgctttcgtc aaatcacgta tagaaggaac agcttttgag tttgaaggta
    21361 tagataccgc agataattgg ttaaataaag aatcctttat taaaagtata gcggattatc
    21421 ttgaaaaaca atggtctaag gaagactatg cagagtacct aaaaacagaa agagatacag
    21481 aggtgaaaga aaaactcact gaggtatgtt tggatgaaca tattgatccc aatatcgtaa
    21541 aacaagaaga ctatgaagtg gttattgata aagttcctac tgattttgag gaagttgtaa
    21601 agtatatagt tgaagaagca ttatcgcaat actcttcaga tgaggaagtg gacgaagaaa
    21661 ctgttcgtac cagagtttgg caactggttt ttgatgacaa agattataaa tatttgagtg
    21721 atcaaaactc ggttaattgg agtgtacgat tattaattga tcaaaatgat attgaataaa
    21781 atagagctga aaagctctat tttattttat aaaaaaacta gctattttat taaaaataat
    21841 ttggttcaaa atttattttt ttaacttgat aattttttgc catccttttt taaattggct
    21901 atatatcaag gtttatagtg ggaataaata aaaatacatt tgacaaaatt tacaatatag
    21961 tttattatat atttatctta ttatgataac acaataaaag gaatggtggt atgaaaaaga
    22021 agaagtttag ccgatcgttg ttaggaattt tggttttagt tgcggttggt cttagtggca
    22081 agggttactt tcagaataac agcactcagg aacatgattt tcagatcaaa agtagtgttc
    22141 aggtaggtaa taaagcagac agtgaatcaa aagaattttt agggatacgt tatgatccaa
    22201 acaaatatcc aaataatatc gtaaacatta atgatgggaa atatacactg acaaaagaag
    22261 atcatgaagc attatcagaa aaaggcagtc aaaccttttg ggtaaattat gcagatttag
    22321 atcaacttgg aagagcagga gatgttgaag cgttgatcac ctatgatgct gtaaattctc
    22381 actcatctaa aaatgtggaa cgtccatctt tcaaaagttc tgtccatatt gcaggagaat
    22441 acaaggatgg agtatttgat caagagagag atacttgggt cggcaaagat tcaaacaatg
    22501 aaatcactca gctagaaggc tataaaggtt atctctataa caaaagtcat tcattagcat
    22561 ggtcgctagg aggagatatg gaggtacaca atttaacact tggaacgaga gcgcaaaatg
    22621 ttgggaaaaa tgatcagaat ggagggatgg cttactcaga aacgattgta cgtgatgcaa
    22681 tctataaaaa taagaatgaa aaagtattgt ataaagttga tccaatttat aaagggaatg
    22741 aattagttcc tcgtggttct catgtcgaag ctttctcagt taacgataat ggaaaaacgg
    22801 taaaccttaa tgtttatgta tttaacaatc aaaaaggaat caacatcaac tatcaaaatg
    22861 gtacttgggt aagagattag aaattgagaa ggtgaagaat tggaaacaat aagcatcaat
    22921 ggattagata aatcagttgc aaatcgaata aaaaaaggaa atggctacta tcttctgaag
    22981 aagggtaaat attcagttgc tagagagtta gaaacaatga gtatcgtgta tgtagctaag
    23041 aatcattttg acgtagaaca ggctattttt gatccagatt ctgaaatagg gaaatgtgtt
    23101 gaattatcag agaaaactgt tagtacaaaa ggggtgatga tcattgagag agaaatgtta
    23161 gacgaaatca gagtaatcat tcctaaagat acgcagatgt gtgaggacag cataagtgac
    23221 gatgaaccaa aatcagaaag aaaataagga gatattcaga tgatcaaaaa atccattgaa
    23281 ttaaaggaat ataagcgaag cgatggagaa aaatattatc ctgtagccag tttttctaaa
    23341 tcagtatatc tggttggacg tgcattgata gttggtgcaa ttggcatata tattttgcat
    23401 tgggtaacaa aggttgtaca actgcttgta gataccttag taagtattct tgtctcgttg
    23461 aatgatgtta acggaacaga tgatttagga ttgaaagaga tgtttaaaga gttactcaat
    23521 gcgttttttc caaattattt aagttattca tataatgcac aaaacttttt tgcaaagcta
    23581 cacttggtag acatctcaat tttagtatta gaagcaggag cggtattctt tgttggatat
    23641 ttggttacat tgatgttccg gcatcactat ggagaacaaa gaccattttt tgatgatatg
    23701 gaaagtagaa ggttgaaaag agaagctcta gaagctatgg atgtgaagta tgatccaaac
    23761 aagattatag gagatgaaac gaacaacaaa aaaagaaaac gacacaaaac gcaattagaa
    23821 tccgatgtgc tatcaacgct taaaaatatc aaaatttctg ttcatacaag acgtgatcta
    23881 agtgtcaatg aagatattcg agaatatatc gtaaaaatcc cgcaaccaaa agggaagaaa
    23941 gttagagaaa cagttttacg acaaattcaa gatttagggt cgatcctgac aagagcaaca
    24001 agcggacgag ccaaatttgg tgaaaaagaa gatgaagttt caggcgatta tttcattttc
    24061 cgagcatcag taaatattga aagagaacgt aaggaaagag taagtactaa aaacaaagaa
    24121 acggaaaaag caacatcttc aatcgcagtt tcaaattcac aattttcttt tccaatcaat
    24181 ctctttgccg ataattccaa aaatatccaa aaccaaaccg aaaaagctag aaaatatgcc
    24241 gaaactcaaa agcaatcttt agaactttat ctatcttctg ctgacgtacc tgcaagtcta
    24301 acagatatgc acgttgggaa tacatctatt gaatatttgt ttactttatc tcgtaccaga
    24361 aaaattcaac taagctcaat gaaagaagaa attgaaactt acttgcatat atcaggtgta
    24421 atcgtgcgga tcaacgcagg acgtattcaa attactttac cattaggaga aaatgatcgt
    24481 attccaattg atgtaccatc aatgatcaat agcgtgtttt agaagacatc acaaatagaa
    24541 acagaaaata caaactacca gttcacaaac agaaaagtac cgagaaaagc gaggaataga
    24601 aatggctatg aaattattag agaaagtcaa aaaaagagca gaaaaagctg aatccatttt
    24661 gctagataaa gaacctaata aaaagcttaa tggaaaattc agtgtcaata tgttgaacac
    24721 aaaagctaaa gacccgacag atgccattct tggaattaag cctgatggaa caattgctca
    24781 tttttgcatt agcgaaatgc cacacttgtt ggttgcagga acgacaggat cagggaaatc
    24841 ggtgttacta aatgaaattc ttgttacagc aatgtgtcac tcaacgcctg atgaattaaa
    24901 aataggaatt gtagacccaa aaagggttga atttggaaga tacaaaaaat tgccgttcat
    24961 gttggctgat ccaattacag atatggatga agcttatgat ttttttgaat atcttgtgat
    25021 cttgatgcat gagcgttaca aactgatgga aaaagcaggg gtacaaaaaa tcacgctata
    25081 taacgaatat gccgaaaaaa atggattaga tagatttccc tatgtgatct tattagttga
    25141 tgaatattca cagttggttg gaacacataa agaagtagaa ggtttgattg ttcaattagg
    25201 acaaatggca agggcagcag gtattcatgt tatcctcgct acacaatctc ctcgatcaac
    25261 agttgtcact ggtattatca aagccaattt tccgtcacgt gtttgcctta tggtagcaag
    25321 tgatttagaa agtaggatcg tattagatga aggcggtgga gaaagcctaa gtccaaaggg
    25381 agatatgatt attaagcacg ttaatggaag tatgattaga gcgcagggag cttacatcag
    25441 taacgaagaa attgaaacaa tcttcaatca ccttagaaat actatgccag aaccagaata
    25501 tgttgattac cgagcaattg tagctgaatc tcgtggtgag ggtggagaag acgaggattt
    25561 tggtggaatt ggtaaagctc ctgtaagaaa atctgctaaa agaaatttaa gcacaccttt
    25621 agcaaatcca tcatctaaag agccatcaat tgaaaagaag agtgcgtttg ctattaagct
    25681 tgagaagaac aaagaagaaa aagtcgagca gggagctaaa acactagaaa aactgcaagc
    25741 agaaaaacta gaaaaagttt taagggcttt aggaaatgct gatcctgaac cgcaaacctc
    25801 aaacaacacg aataataaac agccgattac atctaaaact aaaccgaaaa ctactgatcc
    25861 gaaagtttca gtaaacgtga ccatcacaac cgataattct gagaagaaac aagtaaacgg
    25921 aactacttca cctatcatgc aaaaaatgtt aaaagaaaaa aaacaggtgc ataaatgatc
    25981 attgtcagtt cttttttgag gtggcttacg ccatataaat atacagatga agtagttgtg
    26041 aaacgagcta agaaaaaaga taaaaaagca gtgttaactc ctaaacagat gcttgatcat
    26101 ggaattttgg gtgtgaaggt tttagaaatg aataaaccgt ttgaatcaaa tagtgcaaga
    26161 gaaaagttac ttggtgctga agcagatgtg gcatattttt atcatgacaa aagcaagcat
    26221 caaatagcta ttaaattcaa tccaaaatcg gcatggcggt atcaagcaag agatgacttg
    26281 aaacgtagga aacttagacc aatgctctat ccagaaggaa aagaagcatt tgatagaacc
    26341 cacatcgttc ccatcggttt tcatggtaca gaatcagata atcgcctatt agtaggttgg
    26401 aacagcaatc aaaatagagt tcagatcaat aaatttgaga aggaagtaag aaaattcaac
    26461 gatcgaaaaa caatcctatg gtttgcagat atttgtaaac agccggatgg aacagcaaag
    26521 tgggaagcgg tgatatttga cgaaaatggt aaaaaagtaa tgtctgaaac atggcatgat
    26581 aaagctaaat ttgtttggca gtagcagtag aggtgaaaaa gattgctaga actttttgaa
    26641 gcaaatagaa caggctttaa tcaaaaatta gaagtgggag aaactataga atataaagat
    26701 aaaaactata ttattatcgg aatctataac acgaggatta acagaatagg tgatccacgt
    26761 ataaccagtg acttggtttg tcaatctgtt aactattcac ctgatctgac aagcatgtat
    26821 aagaaatacg tgttattaga atatagacac aagattactg atgaaattgg tgtaaacaac
    26881 acacgaaaca tatttaagat cggaacagtg attccttata gtaacaacga agaaaaaata
    26941 ttttatcaga tttacggaat agaaaagttt gaatatgaac atgtcgatct gctagtgacg
    27001 taccaaatgc gtttaataga accttggtca caggcagaaa ttgataaagc agtaaaattg
    27061 aaccgattat caaaatttaa cgtattagga aatgcctttt aaaaatcgca atacacaaac
    27121 agaaaaatac caaaaaatta gcaatgaacg taggtaagaa catgacaata aataataata
    27181 accctaaaaa atataatgct cttgtccaat gctatatcga aaacaaaatt acaatgcaag
    27241 aagtcgctga tgaattaggc aaatcaaaga gcctagtatc acacgatttt aagcacaatg
    27301 tttttccgaa cccgattgag ctgaggaaaa aatttcaaaa gagagtttat caagaaatag
    27361 gtaagtggat tgatgaaggg aatgcaattg accctttaat tgaaaaatat ccttttttaa
    27421 aaagcaaaaa taaaattcaa aggttaattc gtcaaggcga tattcaagct aaagaacctg
    27481 ttttgacaac caatgatttg gctaaaataa atcttcataa acaaattatt gaagactttg
    27541 aaaaaaatct ttcaacaact gaaattttaa aaaaatacaa tattccgaga ggaaagctaa
    27601 catcgactct ttttagagaa tatggagaat cggcagttac taaagcaaag gaagtagcga
    27661 atgagagaaa aaaacaaaaa tagtagtcga tacctagtgg cgactgtagt ttttgtttgt
    27721 gtattgattt tcctgtttga ttttttgcag gttggaaaaa gcataattgg aaatacattg
    27781 agtgcaaagg aaatggttgc tttaggtggt ttgtatgaag gacacttgtt cccgaatata
    27841 ttcatttcta tcgtttctca tattaacttg taccatttaa tttctaattt attgttctta
    27901 gtagttcttg aagaagcgct gaatgatcag tatgagtggt taacattatt gatcgtttta
    27961 atcatatcag gatttctagg aagcttagtt ccttttctgc tacacagcaa catcgtaagt
    28021 atggggctta gtggaggtat ttttggatgg attgctttat ttgcgattgc atacatccgt
    28081 tttgatagca agaaacattt attactaagt gtttttgtat tattgataat cggcatttta
    28141 ctggtatcta cttttgaatc aggcgagaca aacgtcttgt cacatgtaat cggatttgtc
    28201 tgtgggatga tcttgggatt tattctaaag aacgtttcat tgatcaaaca aaagaattaa
    28261 aagggagtgc taaaaatgcc aaaaaaaaaa gaaaagaaaa ttccagtgtt tttgtctgtc
    28321 tcagaaatgt tatcacttca aatactgtta agaaaaaaga ttgaaacaat agacgaagaa
    28381 gttagaaata aaagggctat gtacgaacaa cgtgaagcgc taagagaacg aatccactat
    28441 tttgatgata tacacactaa aatctatgaa gcacgtacaa atcacgaaga cgaaagcaaa
    28501 ttaggattag ctcaacaacg aatatttgaa tggctgaata cgaatactga gcaagaaccg
    28561 ttaagagcaa ttagtaatct ttttgaattt ggaacgaagc attggtttaa cgctgtagaa
    28621 aaggatgctg acttacaaga agcctttgac acgctaagta aggatagcaa atctatgcga
    28681 gatttattga ttacttatct aaatgagcat gagtttgaac aaacgaaaac caaaaagaaa
    28741 aataaagaat agaaagttgt gatgaatcat gctattaacc ctgttaggtt atttatgttt
    28801 aattcttgct ttttttgggg caatcgctat aattattggt caatttcaaa caaataatcc
    28861 gattatgcgt aacataggta ttggaattgt gattgtaacc tttattgtgt ttaatgccac
    28921 taagattttt ggaagtaacg ataaacaatt tggtatatcg ggagttaata atagttatgc
    28981 tccagattct ttgggaaggg tagtaataga tggaacattt gaaaatgtaa cgagttataa
    29041 aaatgtttcg ctgacagtga aggaagatgg caagaaagca tcagacgacg ttctcgctac
    29101 tattaagccg tcacaatcac aatttgaagt gttttataca gtcaaagaga atagccctgt
    29161 acacaagctg acattggttt ttaacgttga tggagaagaa tactataaag atgtaaaaat
    29221 aaataaaaca tcaacgaaaa agattatcga atcagcgaaa aaagaagtag ctacagaaga
    29281 aagtacaact gaatcaagtt ctactgtcga agcggaacta ccagataaaa ttgattttga
    29341 tcctgaaaaa gtcaaatcgt ttgaatctgt ttctggttct atggctgatc ggtttaacac
    29401 tgaagtcttc aaagctatca aaactgttaa attggatact gaaaagcaaa tgattaatgt
    29461 taccttattc aattcagttg aatctatgga tcaggataaa aaagttacgg ttgcaagaga
    29521 actaggaaaa agagtaattg gtttgtatcg tggtactgct aaaccagatt cagacggtgc
    29581 agatttgcca gttcatgtag tttatgaaga cggtaaagtt tttggagatt ctacagcaaa
    29641 cgaagcatta acgattaaat tggctaaata gccagaaagt tataataaac aaatggtgtc
    29701 acaccaataa tatataggtg tgacaccttg gagatgatag ctgatggtag taaataaaga
    29761 aaaagttaga aagtatgtga ctttaaaaat agcttctgtt aaatatttag aaaagcgagc
    29821 taaagaagaa gaaagagcaa gaggtaagaa agtaacagtt tcagagttgt tagaagaatt
    29881 gatcgagaat gatcaaacaa taagacgtgc atttactaat aggtctatca gataacaata
    29941 taattaataa aaaagaaaga gtgatttggt cttagactaa atcactcttt ttatataaag
    30001 tttctttaca cttattccga ataatgttaa aattctttat acgatatata gttacttgtc
    30061 agagaaagag ataaccagca atattggagg gataataagt ggaaaacaat aatgatatta
    30121 gacattttag cattggggaa agagttacaa cagtaagtga attatcaaag gattatagag
    30181 ataaagaggg aacgattatt tctcttaata agaatcgaag aggcgtttgg caatatgttg
    30241 ttgatttagg tgatggcgtt acagttgagt gtaaagatag tcaactgatc agaaatgatg
    30301 gcagtcattc cattgaaaaa gcaattcttg tatacccaaa agtatcaagt aagatcatga
    30361 atgactggtt gcttggaaaa tttggtgagt acaataaaaa agaaatcgca gaagtgatcg
    30421 gcaaatctta tccaacagta ttagggtatc taaaaaagat aactaacaaa gaagcgaaag
    30481 ttgaggatgt tttaacagta agagaacttc agtcattaat cgaatatcgg aataaacaaa
    30541 taacaaatcc tgagtacctt aaaaaagaag atggtctatt gaaacaattg gaacaggtaa
    30601 ataaaatccg gaagatgcaa aaggtagctc ctttaagcct agataacttt aaaaaaattt
    30661 atttgaaaga gatcgaaaaa gactaatgtg gagtgtcact ttaccgtttc aacctgtatc
    30721 tgcaccaaga ccaagtgcaa gaaggaatgt ttctgatgca actaatgacg tagcagagaa
    30781 aaggatttca acctattatg ataaaaagta tctcgattat ttgaaaaaaa taaaaagctt
    30841 tatcgaagat caaggtttgt tagatgatga attttactcg atcgtaaatg atccgatggg
    30901 tgcaattatg gaagtggact tttactatca gataccaaaa agctataaaa aagtctataa
    30961 cattatgaag acgacagcgc cagacttaga taatttagta aaaagtgcta tggatggtat
    31021 tttcaacatc tcagctatac gagatagcca tatcacaggc ttaattgctt ttaaatataa
    31081 tgtggcgaac gaaggaaaaa cagttgtgag gatcaaacga tattcagaat ttgagtggga
    31141 tacttctgaa ggattgaacg gagatatatg ggaagctaca tttgatttca aaccagtagc
    31201 aacgccaaga ccaaagtcta aatttagagg aaatgggatt atcacttact atccaaaaga
    31261 gtacaacgac tatttggaaa atatcaagaa tacgcttaaa gagaaagatt tggtaaatga
    31321 tcaactgaaa aaggtaatga atgctcctat gggggttata gctcagatag attattttta
    31381 ccaagtgaga aaagataaga aaaagcttga ttcactgatg cgtacttcac agccggatat
    31441 tgataattta gtcaaaggaa cattggacgg aatttttaac aaggaaatag gcatcaaaga
    31501 tagcagggtt gtagggttaa ttgcttttaa atacaatact tttgaaaagt cgaaaacaaa
    31561 cgtgagacta caggagatgg gctgatgaat aataatgaaa aaattcttca tgtacttgat
    31621 agctttgaaa caattcaaga agaactaaag aaatatcggg atgttttgga acaaagatat
    31681 gattttgtca atcagcaaaa gagtaatcac atggatttca ttctcaatat gaatgacttg
    31741 aagaagaaat tagttgaacg aaaagaacaa gaaaagttga tcaaagctta ctttgaactc
    31801 ggtgaaaaag aagttaaaaa ggcaatggaa ctgaatgaag atcgcagggt tttagatcag
    31861 ctgttagaac aattattggt gatgtttcaa aaaggacgaa tagatgagga tttaattgaa
    31921 gaagggttga gaaagtatcc ttcaaactca ggtatcggaa tagtgctgaa agcgattgat
    31981 gaagaagaaa ttgaagcttt cataccgcca gaggattttg aatcggcaat ggaatatata
    32041 aaatattata gccaagggat cactgctttt agagagtttg atcctgaaga tgttattcat
    32101 gacttgaaca acctaaaaga atggtgtgaa agttatgaag tcgatgattc cggattggac
    32161 tacttgatca gtattatgga aatcgaagaa gagatgccgg ataagcctga tccaacagat
    32221 attttagaat tgatccatga agctagaaat ccaattgcct atatttctag aggatatact
    32281 gtattggaat actataagcc ttatatatca gcgatgaacc atttaagacg tgtattaaga
    32341 gaaaaacgtg aataccgctc agtgttgaat gcaacgaata gattagaaaa agctgtttca
    32401 gagctagatg cttattatcg tgaacattac ctgcaagcag gtggtatgcc aagaaatacg
    32461 aaagcaaata tcagtaggta tataaaaaaa gctgagtagg cggagttagc ccgtaaaatg
    32521 gcaaaaggta acctgaaagg ggcattttga atgaaaaggg atgtttttga attgtacgta
    32581 ttagaacgtc tagaagacgg catgatggca caagagataa ttgatgaaat tgatgatatg
    32641 atcagcagat ttggtcaatt ggagttgaat gatggaaaca aaaatccggt agtgctaaaa
    32701 caattttggt tgaacaattt ttcgtataag gattttatca aagaaaaggc aaatacattg
    32761 tactgactaa attcacgagg agcagtgatg agagcttatt gctaagagca gttaggctct
    32821 ttttttgtgt aaaattattt gttttacaat acacatttat acacaaaaaa tattgacgga
    32881 tagtacacaa atgtggtagg atatatttgt aagcaagtta gattaacaag ttaaaggaag
    32941 gaagagcagt tatgaaaaaa gaagaactaa tagatatatt tcaaattgtt gaacgagcaa
    33001 ataatatggg aattatgttt tttgatcgta tttctttaaa gatggattta agcgttgccc
    33061 accaagaatt taatctacga ttaaaagcct tgttgaattc tgatgatgtt aatttcgctc
    33121 atgatgttgt aggcatacag aaccatatag atagagaaaa caaacgtatg ggtgatggat
    33181 tcttaccaag atattcaagt ttataatttg aagaaagatt caagagtatg tgtcattatt
    33241 gataggtact cttgaattgg aaaggaggaa tgaatttaag acaacaacga ttatgatctt
    33301 aaaacaatcg tttatgtaat tgacaatctt acgaataatt ttcatgcaat aatgacaata
    33361 aaaatgaaaa ggggtaaaat caaatgaaaa aaattttagt aggaattcta ttcacaatgg
    33421 ggctagtgct attatcacct tcagtttcag cagaaagctc tatttccatg tatcgtatgt
    33481 acaatcccaa tagcggagag catctataca ctagaagcgt tggagaaaga gacaatctga
    33541 aacgttatgg atggcattat gaaggtgtcg catggcaagc tccaacaagc ggtactcctg
    33601 tttatcgttt gtataatcgg tataacggtg aacattttta caccattgat gccggagaaa
    33661 gagataagat ttcgcacaca ggatggacgt acgaaggtgt tgcgttctat tcctacaacg
    33721 gagcaaatag agttcctgtg acacgcttgt acaacaaata cgtgaattgg caccattaca
    33781 cgttagatca aaatgaaaaa aatatcatta gtcgacaagg gtggaaaatc gagggaactg
    33841 gttggtatgc aatgccaaac agcgcaccaa atcctgcacc tgctccaagc aatgaaaaag
    33901 tgttaaatgt tcctgtcatt tggcaaggta atacgatgtt gtgtgaaggt gcttccctgt
    33961 tagagggatt gcactacaaa ggagtagcga caaatcaaaa cttaaccagt tttgtaaact
    34021 atatgccaag agctaatgac aataatccat atcatggcta ttctggcgaa tggcgctaca
    34081 acgtaaatgg tacgtatcaa ggcatgatgc ctgatccagt agttaaatgg gcgaaaaatg
    34141 ttggtggtaa tgccgttaat atcactggtt caggaacgaa tgggatcaag aatgaaattc
    34201 gcaatggtaa tccggttgta acttggatta cttataacta tgcgacgcca gagttcaaac
    34261 aaatgccttg ggggcgtgcc gtttggaatg ggcatgttgt tttggtagac ggatttaaga
    34321 atggcgctta ccatgtagtc gatcctgtat ttggagcaaa atggatcaat gcaggcacgt
    34381 atgaaaaatc gttcaatgta actggcatgg cggttgctgt acgttaattg atagaattaa
    34441 taaataaatg aaataagagc ttaattactg aaatggtaaa taggctcttg ttttttagga
    34501 aaaaactgct ttttgtaata agaatatata acaaaaaaat gaatttagta cacaaaagtg
    34561 gtatattaaa accgtagaga ttatgcgaag aggtaatttt gatgaaccaa agaagaagaa
    34621 aaagactaga agaaataagc gagcgactat ccgagttaaa ggatgagtta gaagtaattc
    34681 aagaagaaga ggaagagtac aaagaaaata tacctgaaaa tctacaggga tcagaaagat
    34741 atgaaaaagc agaagaatcc gttgatcaac ttgaagaagc tgttgatggt ttatccgaca
    34801 tattagaatt gattgaagat atagctagct agagatgatt aatgaagatt tcaggagtga
    34861 gcaaaaaatg attgatattt cactgataga aaagctactt ttttcaaata agtacacagc
    34921 caaagagctg gctacaagat ggcaaatatc cgaatcagct attaaagcct atcgtcaaaa
    34981 taagggaagc gtaggatggc gtgattggaa aggaatcagc attggaaaag cagaagagat
    35041 aatgaaacgt gaaggatttc aagctgacaa tgattctaaa aaagttgaat agtttaatag
    35101 tagccaagaa aagtaccagg gcgaaaggta gattacaaag gaaaacactt ttaaataaac
    35161 ttcgcaaaag catcaggtta tgagtggcta gggctatacg aatgagatga aaacaaaggg
    35221 ctttaatgtc aaagaaaacg caataggggg gaataaaatt tttaaaaaag atatttatgt
    35281 ttggtttaat ggaaaaaaat atatgactac taacaaaagg tggtcagagc tagtacaaaa
    35341 tacagttaaa aaagtcatgc cagatggata tcatttcaac tatatacaat gctcacaaac
    35401 aactgaaagt atttattttt caatattaaa tgagaataga ctctattatt tcagggtaag
    35461 ttcacaccat aggaaaaaga gggaagataa tgttacgaca tttttatcgg gaaaatacaa
    35521 tggtttcaaa gagttaagtg aagcaattgg tgagtatcta aaaagtaata gatttgtcag
    35581 aatttctgac aaacatatat tgatcttgtt actttatttg aataatagct tcaaattgtt
    35641 ttggagagac gacacattct actatataga gaacggcatg gatatttatt ctggtatcaa
    35701 cggcacatta aaacattata ttaaggcgtt acttcgatat ggggttcttt atcaagaaga
    35761 tttaagtaac caaattaaga ttagtaattc tggaaagtca ttactggcaa aatataaaaa
    35821 attgctttct cctatctaca aaggaataga tatggaagct gtaaattctg aaactttatt
    35881 taatttagtt gttgatgaaa agtttgcgaa tgaatttttt aaaagtaaaa aaattgaaag
    35941 cctaaataac ctgtttcctg aaaatgcaat aaaagcttat gtagataata ataaatcacg
    36001 attatacaac tggtttattc ccaaacggtt gcgaggaaaa atcaaaattg gcgatcaagt
    36061 gaaagtaatt aatctaaatc atactaagat cgttaccgta acggagttgt atatagctga
    36121 aaaagaagag attacaaaaa tgaaaccagt tattaaaata ctagataaca aagagtgagt
    36181 ggaatatatg gtagcaaaaa agaatactct aaaagaagct tctgaaaaat atcaagatat
    36241 gaaaagacga ggattaatac caaaggacaa aaaaggtata tggagagaat ttgttaagga
    36301 agtcagtagt gatcgaagtg gcggtgactt tgttggacga tatacagcaa aaggttatag
    36361 caggcgctta aggatcactg ttgaatatgg aacaaatgaa tcagctacag agctgaagca
    36421 aaggtactta gatacacgaa gagaagcttc aaaaaaatat gatgatttca agagcagagg
    36481 tctaattcct aagaagaaga aggggatttg gcgtgagttt ttcaaagaag aagatagcaa
    36541 tcggaataag ggagacttca ttggacgata cacagcaaaa ggctacacta agaatttagg
    36601 gatcaaggtt gaatacggaa ctggtgaaag ttcatgggaa ttgaggaacc gctatttaaa
    36661 tacattattg gagaaataca aagcagaatt attagagctg ttcgatgtta atgatttcat
    36721 agagatggct gaaaaatatg gtcatgaaga aggctttatg atcaatgaca ttatggttat
    36781 tgataatttt acggacttat taggacttgc gaaaaaagca agagatttaa gagaaacaca
    36841 gatgtatcta ttcagaaata aaaacggaag aaaccggaga actgaatcga gcgagatcga
    36901 agattactat gatgccttta cacacgatct aggagccttt gtagacgaga tcagtggtgt
    36961 tatggacaaa tatagggtct agaataaaaa agccggagat gagcaaataa atgggaaata
    37021 atagcatata tacacctgaa atgcagaata aaattaaaag acttgtcgga ttagggtgga
    37081 tgacaagagg taagttagat tcttttagta cgatcaaata tcttttgatg gatatctacc
    37141 gccaaaacaa gaaaacagga atacattttt tgggctatga taagccggaa gatgcgcctt
    37201 tctttgttcc tagttcagcc tatagagcca gtacttccgg tagcatgtat aacttggatt
    37261 tgtttgagga aggagcaaag atgatcgaat atgattttaa cgaagcctat tcgaggatca
    37321 tgagaaatta tcctttgccg tcaaacactt atttgaaagc aaaatataat acagatcaag
    37381 ctattttgag agcgataaat agaccaaaag taagaccgta tgaaaattta aaaacgtata
    37441 tgttcttttt ggttaatttt gaaggaacag ccaaagaagg aacgtatgct aatccaaaat
    37501 cacagtcgat gtttgcggat tatggcgaaa atcccaaaac agctaatgag cctatttggc
    37561 tatcggagat tgagctaaca ctaatccttg attattatga tatcaaagag atggaagtcc
    37621 tcgatagtca cacatttttg acgaaaaaag gattactcaa agaatatttc gaaagaatcg
    37681 aaccattaaa aactgatcct gatacgttga aactttataa aaatcttaga acgaaagtat
    37741 ttggtgctat cggacaaaaa tcattaagag aaggagaaac aaacaccttc gataaataca
    37801 gtatgtataa tcgagcgtat tcctccatgg tagcaggcgt atttagagat cgtatggtta
    37861 ggtatgaaca gaaatacgtt catagcgcat atgggctatt aaaaatccgt actgatggat
    37921 tgtatttcag atccgaagta ccagagtttg aagagctgta taaacttgga gtagttaaga
    37981 aaaaagttca tacaatatcc aaagaagaag tcgaaaaagc tttagaattt aaaaacaaag
    38041 gatttgaaaa taagggctcc tttgggaact ctaaagatga agttaagggt gttgtgatag
    38101 acgatgattt cgagtttgat tttgactaaa tactctttgg aaaagatggt aggaggtaaa
    38161 tatgaagaag aaaattgtgg aaggaaatgt aggtgttatt attctaaaag attcaactga
    38221 ctatgctaaa tcaatggcac taaaagacga aaaagttgca cgcatggata aagatttagt
    38281 tgaatttctg atggatgata cagaaagatt aaaaggggat cagtttttga gcttaatgaa
    38341 agacaaaggc ttaaacacat atggtttatt tgattataag aaattagcta tagagtgggt
    38401 aaaagaagga gaaatatttt ttattgaaga atgggaaggt actgagaact tagttcttca
    38461 tcagtatctt ttgaaagctt aatctaagta aaacagttct gactagttat gcttgtcaga
    38521 atttcaaagg atgttttcca taaccatcat cattcaaaaa taaaggattt gaaaataagg
    38581 gttcctttgg gaaatctaaa gatgaagtta agggtgttgt gatagacgat gatttcaagt
    38641 ttgattttga ctagattttt ttgcaatgtt taagagtaaa caaggtaaga actaagatca
    38701 tgaagattga gagtaaagaa gatagaggac gaatgtatga gaacacacta tatttattta
    38761 gaagataaaa ttgtagatga aattccggca aaaagtcgag aacaagctag aaaattattt
    38821 attgaaaaat acaaagaaat caatggagat agtgaagttc caaaagtggt cgtaacagtt
    38881 agaaaaaggc aaacaaaaaa gagaagtacg tttcatgtca gccctgatat atataatctt
    38941 atagagcgac atagaagtga agataatatt tctatatctc aatatattgg tacagttatt
    39001 gatgaattga tttcaggaaa atatgactat gtagaaaaaa gagttctaaa tattgaactc
    39061 tttttttatg cttaaaattc tcttgtaatt tttctattca atcaataaat aatccatatt
    39121 taagaagaaa tatgatgata gaaacatctc ctgaagccac cgcaagccgt tctaagcata
    39181 gcttagcccg acattgctag atatgctcat ctcaccatga acgtttccta aagccaccgc
    39241 aagccgtcct agccattgcc tagtccgaca tcgctagatt agtgcatctc gccataaaag
    39301 ttttctaaag ccaccgcaag ccgtcctagc catcgcctag tccgattttg cttgatcggt
    39361 tccatttctg tttatttagt gggtcaacac cgtaatctta aatagccatc gcctatttaa
    39421 gattactagg tctgctttga aggtaaaaag tctttcattc ttcaagactt ttaggctttc
    39481 aagctacgcc tgaaagcatt gaaattcatc gctctttatt tggttttgcc atttataatt
    39541 ccttacgccc attatctttt tcgcctgtct tgccttgtca gaagtgttta gagcttatct
    39601 catctttgga ttaatacaag tggcgtaaat ttttttctaa acgcaagcgt tacgaaaata
    39661 atttacttaa acacttgtat taatccggca gataagaacg cattctaatc actcccgaca
    39721 aggcaagaca ggcgaaaaag ataaataaat gaacgaaagg aagaaacata aaatgcaaaa
    39781 ccaaatagcg atgaagaaaa aaccacctcc ctctaaaaca atccaaacaa aaaagaattt
    39841 tgaaaaacca aaaatcaaaa acagaaagaa gcgttcaaca tgagagatag aattttagaa
    39901 gttaatcaag aaatggtaaa caagttaaca aatatcagtg ggaactatga aaagtacgat
    39961 ggtactttac ttgataacta tatttttcac gatacacaaa atatcagaat tggcagaagt
    40021 aaaccgagag cgttcattct catcaaagag aaatatttga atgaatggaa tagcacctat
    40081 gaaatggtta tgactgataa ctttgaaaag gtattggatt tcagaaatgc tttgttgggt
    40141 tctgatatgg gaaatagcag tcttgaatct attgaagttg aaaacaagac cgagaatgaa
    40201 ggtgaaggat tgattaagaa tgtcttgaaa atcgaacaaa aatatatcag tgaagataga
    40261 agtttttata gagtcacaag ctcggttggt ctagcaaact ttgctactaa cttaattgga
    40321 aacaatgcta gtgaatcttt gctagtgatg tgtctgaata caaagaatga ggtcattgct
    40381 tatagcgaag ttttcaaagg tggaattaat caatcagtag cgataccaag agagattttt
    40441 caactagctt tgctaaacaa ttcagcaaaa atcgcagtat cacataatca tccgagcgga
    40501 tatgaatttc caagtgaaaa tgacaaaagt tttactacga atttgaaaaa cgcaggaaaa
    40561 acaattggta ttgaattgtt agaccatatc atcgtaacaa gtaaaaacac aagctattac
    40621 tcatttcaag aaaatggttc tttataaaaa ttagagaaaa gaggaaaaca agatgggcga
    40681 aagaacacaa gcgttaatta cagtcaaata tggtaacagc aaaacgaaag caagcgtgtc
    40741 gattcattat cagtgggggt atggtcgata tatgctgatg gacgtattga atcaaggaat
    40801 ttatttaatc aataaagcat acgacttacg agataaatca agagaagaat tagcaaaagg
    40861 aatctttgat agaagtacag gagttatcaa ttttgttacc tatgaatctg gagtgagtgc
    40921 ttatgatgaa acagggtttg gtgggcgcta tgaaccttat caagaaacga ttgaagatgt
    40981 gatgaagttt tcagataaca atgatggcta tgctcattta gagatggtgt tcgatgaaaa
    41041 tggatttagt ctagatgata aaaccagatt gcgattgttt gattttgagg gtcaacagat
    41101 aggactaaac aagttttgtg aaagcggaaa agagtttgct acgaaagatt ttattaaggg
    41161 atacagatta ttgttagaaa attatggaat aaacctagaa gaagagagcg tgaaataagt
    41221 gtttgaaaaa agaaaagacc agttccctaa tttagaagcg aaaagtcaaa aagtgattga
    41281 tggtgaaatg attgaattat tccaaaaaag ttatggaacc atagaaacta ccgcaagttg
    41341 caaatactac tttcaaggaa agagaaacac gtttaaaggc tttgccgatt ctgatgaaga
    41401 attggcaaag aaaatcattg attggcttgt cagcagtgaa cacgtagcaa gagaagatac
    41461 cgttagaaca acgattaatg gggaagtcct aacaggtact agatgtgttt gttgtaatca
    41521 tgaatttgta gaagatgaag gttgctaccg aatcaatgaa tatggtgatt ttatttgcca
    41581 gagttgccac gagatagaat ttccaaccga aagaagttgg tttgaataca tgctacaaga
    41641 ttatgagatg gaaaaagaaa atggtgaagt agttttttgt accaaagagg aattgagtaa
    41701 gagaagcgat gatgaaattg aagattggtg tgtgtggtta gtaggggcag atgattgcgt
    41761 tgcatattac acaacagcag aataggagtg tgaatcagca tggaaggaat ggattttcta
    41821 gatcatgaag atttggttga ttttggttat acatggaaag gaatggtagg tattagcaga
    41881 agtcttgcta atgcctttta cgaaagaaat tatgcagtat atgttcttta tgatgacgat
    41941 acagaaagcc ttgttgacga ggaatataaa ttggatttag agaatgtttt atatggaata
    42001 gaaaaggaag atttagcaaa atatattttt tcatggttgg gtcaataagt gaaaggaaga
    42061 tagaaacatg acaaaattta aaagtaaggg tatgcaatgg tgttcttatt attatgttgg
    42121 aaatgatgaa gatttattga gaaaaaccca acgaaaaggt tatccagata agatattgaa
    42181 acaaataggt tattacatgc cagaagagag gatagaaaaa gaattttgtg aggttctttt
    42241 tgatagtgaa cagctattag ttttgttaac ccaaaataaa ttgatttgcc aatttgaaaa
    42301 taattaagat gaggtggtga accatgaatg aagataagat ggtattaagt gaatatgcta
    42361 gattgagaac tattaattct ttagcatctc atttaagttg ttctttccta acaaaggtgc
    42421 taaaattaat ttacaaatgt gaagattttg tacaagagaa gcacaaagac aagcctactg
    42481 cgaataggct tgtctttttt tcattcatta cgattccgta tgtgtgggtt agcgacaatt
    42541 tgttcaatta ccgtatgata tagcatctta atttgattag attacttgca atgtagttta
    42601 ttaagagtat aatataatca taaatgtgga caatttgaga aataatgagt gttttatact
    42661 caaaaggagt ggatgaaatg aaggtcaaaa atccaactga aaaaagcaga atccaagtcg
    42721 gaatagacaa gaatttaaaa gagaacgcag aaatgatatt ggaagagcta ggtttaaatc
    42781 ctacaacagc aataacaatt ctttacaaac aagtagtcgc tagaggtgag tttccagtag
    42841 agataaagct aagtgaagag gagaagcaag gaatcagatt gcaacagcta actaaggaca
    42901 tgccagtaga tgttctagat acagatgaaa agttagaaga gtggttcgat gaagcctaat
    42961 gagatagtaa cggtctatgt tgcatttaca gataaaaatg gtggtaaaag aagacctatt
    43021 ttggtggtta gtgataaaga agatagagta gaattctttg gaatcacaag tcaatatgag
    43081 aaaaaatcag accaaataaa gagggtgtat tttcctattg cagaatggga aaaagcagga
    43141 cttaaaaagc aatcatggat tgacgtaggg tctttaaagg ctattcccaa aagccgagag
    43201 aacatatcat tcaaaaaggt tggtatgtta tcagctagtg atacgaaaaa gctaaatagg
    43261 tttatcgaga aattacaaag aaaagtctaa caaggctttt cttttttgtt tatatgtata
    43321 ttaagatata cgtttatata aacgtattta tgtatatgaa aatatacgta aatatatacg
    43381 tggttataaa cattaataaa acgttaagaa ttgttaaata gtgatattta gtaatatacg
    43441 aattataaga tatattttat atagaatgta tgtaaataaa taaaatgtct gacggatatt
    43501 gaatagcaat aaataacaat aattcagacg gatacagtga gtgaagtagc ttgctacgaa
    43561 cgaacaggca gaatgaaacg gcagtttcat tagagcaagt cgcttgcgac gtagcgttaa
    43621 cgctgatgca actggcaagt tacatagaga gagtttgctt gcaaacgaac gttacctact
    43681 tgaatagaaa taaaaaataa cagattagtg aattttgaat aggagccaca actcaaccaa
    43741 ccgcttgcgg tgggtgagtc ccacggagga aaagacgaac gaacggtcgc gtagc
//
LOCUS       DAKCAA010000016        43281 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000016 DAKCAA010000000
VERSION     DAKCAA010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 43281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.016"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(19..345)
                     /locus_tag="OUE31_001010"
     CDS             complement(19..345)
                     /locus_tag="OUE31_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222034.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(718..1919)
                     /locus_tag="OUE31_001011"
                     /pseudo
     CDS             complement(718..1919)
                     /locus_tag="OUE31_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            2036..2551
                     /locus_tag="OUE31_001012"
     CDS             2036..2551
                     /locus_tag="OUE31_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCU0222035.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(2750..3196)
                     /locus_tag="OUE31_001013"
     CDS             complement(2750..3196)
                     /locus_tag="OUE31_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCU0222036.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(3243..4721)
                     /gene="msr(C)"
                     /locus_tag="OUE31_001014"
     CDS             complement(3243..4721)
                     /gene="msr(C)"
                     /locus_tag="OUE31_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCU0222037.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(5075..5704)
                     /locus_tag="OUE31_001015"
     CDS             complement(5075..5704)
                     /locus_tag="OUE31_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCU0222038.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(5688..6152)
                     /locus_tag="OUE31_001016"
     CDS             complement(5688..6152)
                     /locus_tag="OUE31_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCU0222039.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(6639..7907)
                     /locus_tag="OUE31_001017"
     CDS             complement(6639..7907)
                     /locus_tag="OUE31_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCU0222040.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(8138..8875)
                     /locus_tag="OUE31_001018"
     CDS             complement(8138..8875)
                     /locus_tag="OUE31_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCU0222041.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(8942..9511)
                     /locus_tag="OUE31_001019"
     CDS             complement(8942..9511)
                     /locus_tag="OUE31_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCU0222042.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            9639..10511
                     /locus_tag="OUE31_001020"
     CDS             9639..10511
                     /locus_tag="OUE31_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCU0222043.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            10853..11725
                     /locus_tag="OUE31_001021"
     CDS             10853..11725
                     /locus_tag="OUE31_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCU0222044.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            11722..13680
                     /locus_tag="OUE31_001022"
     CDS             11722..13680
                     /locus_tag="OUE31_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCU0222045.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(13931..14782)
                     /locus_tag="OUE31_001023"
     CDS             complement(13931..14782)
                     /locus_tag="OUE31_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCU0222046.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            14905..15372
                     /locus_tag="OUE31_001024"
     CDS             14905..15372
                     /locus_tag="OUE31_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCU0222047.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(15635..16117)
                     /locus_tag="OUE31_001025"
     CDS             complement(15635..16117)
                     /locus_tag="OUE31_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCU0222048.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(16217..17080)
                     /locus_tag="OUE31_001026"
     CDS             complement(16217..17080)
                     /locus_tag="OUE31_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCU0222049.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            17678..18526
                     /locus_tag="OUE31_001027"
     CDS             17678..18526
                     /locus_tag="OUE31_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222050.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(18697..19038)
                     /locus_tag="OUE31_001028"
     CDS             complement(18697..19038)
                     /locus_tag="OUE31_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HCU0222051.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            19124..19831
                     /locus_tag="OUE31_001029"
     CDS             19124..19831
                     /locus_tag="OUE31_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCU0222052.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            19818..20141
                     /locus_tag="OUE31_001030"
     CDS             19818..20141
                     /locus_tag="OUE31_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCU0222053.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(20230..21267)
                     /locus_tag="OUE31_001031"
     CDS             complement(20230..21267)
                     /locus_tag="OUE31_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCU0222054.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(21714..22697)
                     /locus_tag="OUE31_001032"
     CDS             complement(21714..22697)
                     /locus_tag="OUE31_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HCU0222055.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(23113..23883)
                     /locus_tag="OUE31_001033"
     CDS             complement(23113..23883)
                     /locus_tag="OUE31_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222056.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(23876..24811)
                     /locus_tag="OUE31_001034"
     CDS             complement(23876..24811)
                     /locus_tag="OUE31_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222057.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(25405..27054)
                     /locus_tag="OUE31_001035"
     CDS             complement(25405..27054)
                     /locus_tag="OUE31_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCU0222058.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(27249..28145)
                     /locus_tag="OUE31_001036"
     CDS             complement(27249..28145)
                     /locus_tag="OUE31_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCU0222059.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(28138..28818)
                     /locus_tag="OUE31_001037"
     CDS             complement(28138..28818)
                     /locus_tag="OUE31_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0222060.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(28819..29601)
                     /locus_tag="OUE31_001038"
     CDS             complement(28819..29601)
                     /locus_tag="OUE31_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222061.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(29594..30511)
                     /locus_tag="OUE31_001039"
     CDS             complement(29594..30511)
                     /locus_tag="OUE31_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0222062.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(30514..30798)
                     /locus_tag="OUE31_001040"
     CDS             complement(30514..30798)
                     /locus_tag="OUE31_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222063.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(31258..31650)
                     /gene="rpsI"
                     /locus_tag="OUE31_001041"
     CDS             complement(31258..31650)
                     /gene="rpsI"
                     /locus_tag="OUE31_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCU0222064.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(31666..32109)
                     /gene="rplM"
                     /locus_tag="OUE31_001042"
     CDS             complement(31666..32109)
                     /gene="rplM"
                     /locus_tag="OUE31_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HCU0222065.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(32628..33095)
                     /locus_tag="OUE31_001043"
     CDS             complement(32628..33095)
                     /locus_tag="OUE31_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HCU0222066.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(33215..34753)
                     /locus_tag="OUE31_001044"
     CDS             complement(33215..34753)
                     /locus_tag="OUE31_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HCU0222067.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            34833..35519
                     /locus_tag="OUE31_001045"
     CDS             34833..35519
                     /locus_tag="OUE31_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HCU0222068.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(35720..36247)
                     /gene="msrA"
                     /locus_tag="OUE31_001046"
     CDS             complement(35720..36247)
                     /gene="msrA"
                     /locus_tag="OUE31_001046"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCU0222069.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(36331..37008)
                     /gene="pgmB"
                     /locus_tag="OUE31_001047"
     CDS             complement(36331..37008)
                     /gene="pgmB"
                     /locus_tag="OUE31_001047"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCU0222070.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(37005..38135)
                     /locus_tag="OUE31_001048"
     CDS             complement(37005..38135)
                     /locus_tag="OUE31_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCU0222071.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(38135..40318)
                     /locus_tag="OUE31_001049"
     CDS             complement(38135..40318)
                     /locus_tag="OUE31_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCU0222072.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(40315..41340)
                     /locus_tag="OUE31_001050"
     CDS             complement(40315..41340)
                     /locus_tag="OUE31_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCU0222073.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(41385..42212)
                     /locus_tag="OUE31_001051"
     CDS             complement(41385..42212)
                     /locus_tag="OUE31_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCU0222074.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(42209..43276)
                     /locus_tag="OUE31_001052"
     CDS             complement(42209..43276)
                     /locus_tag="OUE31_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HCU0222075.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
BASE COUNT        12412 a         9284 c         7777 g        13808 t
ORIGIN      
        1 catataaacg gcgttcgcct accagctgcc tggtaaatct gtttcctctt cgttaagaag
       61 cgaaaatccg tcaaatgttt cgccatcata ataacgaagc agctcatcca tggacaagtt
      121 catcgttttt tctttttctt cttccgctga ttcagccagt agctgttccc gatacacctg
      181 atacatacca gctatttttt gctgcatcgc ttttctagtt tcaccttccg cattgattat
      241 tggcaattct ttgatatagc cacgataaat caaccgatca tctgaaaatt caatgggtaa
      301 ttcaacgagt gtcaacccga cttcctgaaa atattcttcc agcatctatt atccccccat
      361 tctttttctt aaatgaattt tagcttacct actgaaaatt ttccagtttc attattttga
      421 gaaaaaaagg gaatgtgaca aaaatcgtgt cacatcccct ttttccgaat aaatggtgtt
      481 cttctgccaa ctcctcaatc ataagtcaca atattcaaca aacatgagaa actgtttttt
      541 gaaattgttc cttgtgattc agagttaaac gacagtctca caacctcttg gtaaacggcg
      601 ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg aaaaatatga gaagctattt
      661 ttgtttggct gttcttatga cttgatgcag gacagctttt tcacaacctc tgatttctta
      721 ttcttcttca tttgtagcaa aataattacg gtgataaatg atacaacata cactgataag
      781 aacaatggca cctgcaaaat aaaacgcata gctttcacca atatgttcac caatcacacc
      841 tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca aaactatagc tggacgaagc
      901 aacgtttcgt tgcagacctg gtatttccat agcaatcgtc gtcaacagtg tattgataat
      961 tccttggaaa aatcctgcta acacaatgct gatcggtaca aggactggca tagaagttcc
     1021 agctcctaat aacagcaaac aaataatgaa taagacaaat gctgctaaaa ttgtccgata
     1081 agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc gaagcaatag ccagaagcac
     1141 accccagcca aaaaatacaa aaccgacttc taattcagaa tagccaatca ataaaaatgg
     1201 cgcatacgca agtaaagtaa agaatccgaa attatataac aatgcgatta gtccaactga
     1261 acgaagttta tgattgctta acgctttgac accttcccaa aggcctactt ttctctttgg
     1321 tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa ccgcaaaaca tcaaaaatgc
     1381 taccccaaaa aatggataac gccatgaacc actgcccaag accccaccga ctagagggcc
     1441 aacagccatt ccgcagccaa gtgctgcttc atacatcatg attgcttttt ctgtgttacc
     1501 aactaaaata ctgacgatcg ttgctaaagc agtagagaca aataaagcat tcccgacacc
     1561 ccagccggca cgtaacccaa tcagcattcc gatattccca gataatccgc caagaccagc
     1621 gaatacaacg atgataaaca atcctgtcat caatgttttt tcaaaccgat ccgactagat
     1681 aagaaacctg taaatagcat caccacacca gtgactaaca tgtaactagt aaataacagg
     1741 gtcgtttcag ctggcgtagc gtttaactgt gcagcaatcg tttttaagat tgggtctact
     1801 agacccactc ccataaaagc gatcatacag gtagctgcta caactagcgc tgaacttttc
     1861 ccctttgttt cttcatttgt ttgttcttgt atatctattt gattctccaa tatttccatc
     1921 cctttctctc tattagcatc atacatgatt tattttacat gtaaatatgc acatgtaaaa
     1981 cgtggaaact ttactgtgat ataataaaga aaataagacg agaggtagga tttttatgaa
     2041 tactttagcc tatatattat tatgcgtgct tttatccaaa ccacgttctg ggtatgaatt
     2101 gaagcagctg atcacaattt tttgggaagc ccatcacagt cagatctata caacgcttgc
     2161 caagttagac cagcagggtt atgtgaccgt tttggacaaa gacgagcact ctcaaaaaaa
     2221 gatctaccac ttgactgatg aaggacgtgc tcttgtagag gaatggatca aagaggaaac
     2281 tcccgctcct acgcaaaaag atgaatttct agcaaaaatc tatgcttttt cgacgctcga
     2341 taaaacaaca gctactggac tgctattcac tagagaacaa cagctgaaca aaatcatgca
     2401 aaaaaatcaa aaaaaattga atgacctctc gctagacaag aaacaagaat ttggacgtta
     2461 tgttgtgatc cagcgcagaa ttatgctttg tcagcaggaa ctccaatggt gtcagcaagt
     2521 aagagaacaa atgcagcagt tttttgagta agggataaac agaacctttc tagaaatatc
     2581 tattgaagag caaattatct tcaataaaag agcaatacag ttggaaaaga aaaagcgatc
     2641 cgaacgacag gccaaaacct atcgttcgga tcactatttt tctagaactg cattcaagag
     2701 actatgacaa aaagcatgcc aaggcctttt ttcaaataac agtgttccat cattcattac
     2761 tttgaattgc ttttagcaca cttcttgaaa gcgggccaac gatgatcaac tgcaacggta
     2821 aagcggcaat cacattcatt ttccaagcat tcatataagc agagaataat tgatcaggta
     2881 ttccttgttc catgatcaca ccgaataaag acatacatgt caccattcct aaaaccatca
     2941 agcatgaaat agttaagatc atttggacct tgctttctgg atttactggt agtttaaagg
     3001 caattttttt cgccagcaca ccgatgatga agacatccaa aatgaaagcc accacgaatc
     3061 caggcactag accaatcaac aaacttgata aatgaagatc ttgatgcagc cataaattat
     3121 acgcgctcat ccccaagacc atcaaaaaac acatcattgt tgtaaaaatt attccttctt
     3181 ttttatttgt aggcaatctg taccactcct ttaaatttgt cacgaaaatc atcgtagcac
     3241 atttaaaaat ttctcgtaag tacttttttt attttctgcc cttttatttc ataaacttca
     3301 tcagccgtac gctcgacaaa gtaagaatca tgagaagtaa acaaaatcgt tcccggatat
     3361 atttgcatta gcttctctaa agcttcgatc gttgccatat caataaaatt agtcggttca
     3421 tctaacagca acacattact tggcttagta aaaagcaaag caatcgtcag acgggtcgct
     3481 tctcccccac ttaatgtaca taacggtttc gtcaaagttt cctgagcaaa ccctaagtga
     3541 ttcagcaaac tacggacaag cgattctgaa aactctgttt gtctcatgac aaaacgaatg
     3601 atggattctt cagatgtcat ttgataaccc ttttgctgat atacttgaaa gcttactttc
     3661 ggagagagaa ggattccttc tccttgtttg cggatatgtt ctaataaggt tgtcttacct
     3721 gaaccatttt caccgacaat cgcgattttt ttacctaaag aaaactgaaa atcaccattt
     3781 accagtaatg ttctcccact tctttccaat tggacatttt gtcccatgat gggatagcgg
     3841 ctgtggagtt caagagattt tggtactgga aaacggattt gtttcatctg ctgcggcttg
     3901 gttgtttctc ctattttttg gagtcttctc tctaatgttt tcgcattctt ttggatggct
     3961 ttttgtacac tgtctttttg tttagaggaa gacaaccgat ccggtctgat ttgttgcttt
     4021 ttctttttac tggacacttt ttccaacttt tccgcttgtt ttttcttttc ttggatcgat
     4081 ttttccaatc gttttttctc tttcatgatc gactctgctt ctcgtagctg agtctttttc
     4141 tccaattcct tttgagtgag ataggcacta taattccccg aaaactctcg gatttctccg
     4201 tcttttactt cccagatttt cgatgctagc tcatctagaa aatagcgatc atgactaaca
     4261 aaaaccagcg taccataata ataacgaagc tcttcaatca gtcgatcaat actttttcta
     4321 tctagatggg ttgttggctc gtctagaagc atcccttgtt cataagaaga aagaagacgt
     4381 atcaactcga tctttcgttc ttcccctccg ctccatttcc gctctgaagt ttcttccagt
     4441 cttaactgga aatgactggc taattccaaa tttaggtcct ttgcttcagc gagataggtt
     4501 aattgaggca ggtagttgaa ggtgatctct gtttggattt tcccatgatc gggaaaaagt
     4561 tcaccggcta ttagtttgag caaagtcgat ttaccgacac cattttctcc tatgatccct
     4621 atacgatctt gctgatagac acgaagagaa tcaatagata gttctagctg gttgccaaag
     4681 ctgacttgta gatttgttat atttactgct aaattttcca tatgttttac actcctattt
     4741 catgtaaaac aacaattatc gatactaaaa aagagcagaa aaatctgttt gcaaaaaaac
     4801 tgcatcacat cttttcctac tctgaacgaa ataactatga ctaaatcacc aaatctgtca
     4861 tagctttcac ctattctact gtcgttcgaa aaaatggaca tactccatcc atgaaattgt
     4921 tgtttataca tgtcttttga atttatttag ttgttattca aaagttcgaa acgtaatttc
     4981 atcgatgcag tcatttttcc gacctccttt tttattaggt taccacacac gattcaaaaa
     5041 aagcaatagc tactgaatag taactgaaaa ccttttattc gaacgtagtg atcttttctg
     5101 gtgctaaacg aacagactcg taaccttctt ctaccgcttt tcctattgat aaaataataa
     5161 ctggaacata acggtcttta tccaaaccaa atgcctctgc caactgatct gcttcgaatc
     5221 caccaattgg atttgtttca tagccatgat cacgcgcaac taacatgaat tgcatagccg
     5281 ctaagctaga atcgactttg actacatcgt tcatttcttc tcttgaaaaa ctcttgtaat
     5341 aaggaatgat cgcagctaat tgttgatctc tgacttcttt tggcatcttc cctgattcgt
     5401 aagcttggtt atagatttct tcgccatatt cgtaacattg catatcgcca aaaatcatga
     5461 ccattgcaga agaagtatca ttttgtctcg tattgaaacg gatcaaagga cgcaagattt
     5521 cttttgcttc ctcgctttca gcgaccacaa agcgccatgg ttgcatattg acagaagaag
     5581 gtgcagtcgt cgcttctttg atcatttcca gcatttcttc gtgtgggatt ttgtatgttt
     5641 catcatatac gcgaacggat cttctaccag tcataattgt tgaaaaatca tttttttgtt
     5701 ccattattat taacctcttt cgtttctgtt gttatattgc aaagttgggt attcaattta
     5761 tctaaaagtg ttagaaattg tttcatttct acatcgctga aagccgggga tagcacggaa
     5821 cctgtatctt tatggtccat ttcacaatgc tcgattttct tctgggcttt ttctgttagc
     5881 gctacataca cttcccggtt gttctgagga tttctctgac gcgaaacata gccatttgct
     5941 tccaatacct tcagatgacg agtaactgct ccttgatcaa tctgcaactt ttcttgcaaa
     6001 ctgctttgta gcaatggatt ttcttctttc agtctcatca tgatctcgta tctagtaaga
     6061 cttataccga tattttcttc aaagatctgg acgatttttt gatcggctaa tttgatttga
     6121 tataaaaggt gactaatctc ttctaaagac ataatttcct cctttctaat aattgactcg
     6181 tcaacgattg acttgtcaat aatagaataa aaaaagaaaa aagtcaaaga atcagctgtg
     6241 taataaaaaa aacgctctca atagaaaagt atagagaaaa gaaatttttt gtagaatgaa
     6301 cggaaaaaat gataaagaaa gcacaacgct aaaaccaaga ttattgattc ttatcaaact
     6361 atagaagata gctcttctgc agtagaaaat tttacaccgc caaaaatttc cgaaatcgcc
     6421 ttttgcaaga atcccgtcga atattagaaa ttggatcagt atgcttaaac agtaataaaa
     6481 aagttatgac aagatgttgt cacaaccttt tttgagtaaa cggtgttcaa aaacttgcat
     6541 ctgcggtaat aagttcaacc aaacaaaaaa catgaaaatc tgtttttgtt tggctgttct
     6601 tactacttga tgcagggcag ctttttcact acctcttttt aataaccata aaatcctatt
     6661 ccttcatatc tccagcccat cggtgttagc caatctcttt ccttagcact caaggtatag
     6721 tgatgggtac cagttttttc atttggatta aatagtcgat aaattggctt ggaaccacca
     6781 gaataaaaac ttagaccttc ataacgccaa ccgatttttg ttaaagagtt gatctcagat
     6841 tgtgccattg tgtaatgatg gtctccactg taaggattgt ataaacggta gacaggttgt
     6901 ccgctgtttg gtgcttgcca agcaatccct tcatattccc agcctacagt tggcagataa
     6961 tttttttctc cggcattcaa tgtatataaa tgttctcctg tatgacggtt atacagacga
     7021 tacatcggag aagttgaagt tggtgctgta tcatactgtg tcagattata ggtttcgatt
     7081 acattgttca atgtagaacc ataattaggc gcagtggcat aacgacctgt tagccaagcc
     7141 gtagcatctt tgtaagagtt cgtattgctt ttccatgcac cggaatagta gtaaacgcct
     7201 ggctgaaaag aagtcgtctt caataccgtt acgttatctt gcaatgattc tttgtacgaa
     7261 ggatattttc taaaagcggc attcaccgta atccattgcc cattcacata ttccgaagta
     7321 ggcatcgtaa cagattggcc attatagctt cctttaatcc caaatagatt gtaattaggg
     7381 gcagaagcca aagtactgtt cccccagcca ctttcaacga tggcttgagc aatcatgact
     7441 gatgcatata agtcattggc acttgccaaa ctttgtgcag ttgaggcaat actatcaatg
     7501 aacgcttgtt gagaattagc agatgagcga gcataaaaag catagccagt atagttttcg
     7561 aattcagaca aatctgcttg atgggtatgt gtcaatgttt gcccatctgt caattggttc
     7621 gtgatttctt ctgcattctc tggattgttc tgagcttctg ctgatgtact gtcttcggtt
     7681 tgtgtttgtt ctgttgtttc agttgttggt tcttcggttg aaattgtatt ttctgagaca
     7741 gtagctgact gcaaagtact ctctgtatcg ttttcaattc ctgtttctga agaactcgat
     7801 gtctgagttg cgacagtttc tgtcgattct tcagctagca ctgttgtgtt ggcaactgct
     7861 agatttccta aaagaataac gctaaataat aaattctttg ctttcatctt ttttctcctt
     7921 tgaattatga aacttttcct aaataacagt gtaactaaaa aagtaaaagc aagtcaatgt
     7981 ccatatttaa ataacatttg tttctttttg ataaatttgc tttttctaca taaaaagacg
     8041 taaatgaaga atattcttct ccattcacgc cttaaattga tggtcgtttg aataactatt
     8101 taacaagtaa ttctctttgg atattatccg ttatggatta tacttcctgt gtcgtcggac
     8161 ggataatcat gttactgaca gacatccggt ctggcgtttc tatcgcaaat gctacagcag
     8221 aagctatatc ttcggaggtc aatccccatt ctttttgcgc ttcatgaagt tcaagagcag
     8281 cctttttgtc gctgatggtt tgatataatt cagtttgaac agctcctgga gagatgatcg
     8341 tagatttgat gttattttgc cgttgctctt gacgtaatcc ttccatgatt gcacggacag
     8401 caaattttgt tccgcaataa acggcggaat caggataaac aacatgtccc gccacagaat
     8461 cagttgaaat gatatgccca gatttttgtt tttccatgat tggaagtacg gcggaaattc
     8521 catttaacac acccatgatg ttgatatcaa gcatattttg ccattcatca cggtgacctt
     8581 caactaatgg agcggttggc atgattcctg cattattgta caatacatcg attcgaccga
     8641 acttttccat cgctaaatcg ataactgctt ggacttgtgc aaaatctctt acatctgctg
     8701 tttgaatata tagctcagct tctggtaaag attcttttat tgcttttagg cgatcttctc
     8761 ggcgtgcagc tataactagt ttagcccctt tttctgctaa tagcttcgtt gttgcttcac
     8821 cgattccgct tgaagcgccc atgatgacaa tcactttttc tgataaatca ttcattctat
     8881 tctcctcctg ttttgaaaaa tctcttgctt atactcacta tctcttattt catcttactg
     8941 ttcaaataat ccgttcgaca ggtttgacga ttttggcagg gattcctgca acgatggtat
     9001 tgtctgggac atctttcgta acagttgcat tcgctgcaac aatggcattc tcgccaatcg
     9061 ttacgcctgg cagaatagtt gctcctgctc cgatccaagc atttttcttg atgtggattg
     9121 gctttactga caagcctctt cgttcttttg gatcggttag atggttcacc gtgatgaggt
     9181 tgacacgagg accaatcaat actgaatctt ctaaacagat gccacctaag tcaacgaaca
     9241 tcacttgacg attgataaag acatttttcc ctatactaat atgtttgccg aaatctgtat
     9301 aaaaaggcag cagaacagtc accgtatcat ctactttgtc actaatgata ttttctagcc
     9361 gtttgcggat atctgctggt tcatggtacc cagtattcag cgctgctaaa ggctcttcgt
     9421 tttcagcttg gatctgatgg atcacttcaa agagcggatc cgttactcga atctctttat
     9481 tgacgatttg tttttcgatg aggcttgtca ttttgctccc tccttttatc cttactttat
     9541 aacggacggc ttatcatgtc taatacttat aaaacatact taactattcc ttttaactat
     9601 acttagtggt atgctttttt aaaaacagga gggaaaaaat ggatattcgt atactgacgt
     9661 attttttagc agtagctaga gaaaaaaata tcagccgagc agcaaaatct ctgcatatca
     9721 cgcaacctac tctctcaaaa caactgaaag atttagaaga agaacttggt gtgacacttt
     9781 tcactcgggg ctcccgagag atacagttga cggattctgg tcgatatctt tattcaaaag
     9841 gaaaagaaat cttgtcgttg gtagaaaaaa cggcgaacaa tttaacaaat gacgcaatca
     9901 tctctggaga aatctacatt ggcggaggcg aaactaaagc aatctctttc atttctgata
     9961 gccttcattc gttgatcaag gcgcatcctg atatccagtt tcatttatat agcgggaatg
    10021 cagatgatat catagacaaa ctggatagcg gattacttga ttttggactc gtaatcgaac
    10081 cgacaaacaa acaaaaatac cagtcatttc gactgccagc ccaagatcgt tggggacttt
    10141 tgatacatcg aaatcatcct ttagcaaagc aaaccgtcat ccatccgcag gaactgaaaa
    10201 ctgttccttt gatcatttcc cggcaaacgt cagtggacag tcaactagct gaatggctag
    10261 gtttcagcat agatcagtta tcgatcgtcg gaacatataa cttattgtac aatgcttctt
    10321 tgatggtcga taacgggact tttggtgcat tagctctaga tgggatcatc aatacttatg
    10381 ggacggaaaa aatattcatc ccactcgatc cgccattaca agcttcactg aatctcattt
    10441 ggaaaaaaga ccagcctctt tctcctgctg ctcgtaaatt tttagatgtc ctaacggaga
    10501 aatacagtta agtagagttt ttttccttcg ctttcagctt tttaacaacg aataagataa
    10561 gcaaaagatc caacgattaa ataacataag tttcttaatt tatttcttcc ttttatttct
    10621 gataattcca gtaaattact ataattataa aaaaagaatt gacaaaacat aactgtctat
    10681 ataaaattga ttacgttaac aataattcgt ttcatgtgac tagatcatac taggcatgaa
    10741 aaatctctga ggaacatggt ttccctagga ggtttttcgt gtctattttt gtttggccgc
    10801 aatcaactgg tctagcaaac gtgaaaacca aatcttcaaa aagggtgcgc gcatgaaaat
    10861 caaaaagatc tttaatcaaa atgcagtatt ggtagatgac ggtggacagg aaaaagtagc
    10921 tattggaaaa gggattggat ttgacagaaa aagaaatgat ttgatttttg atcgtgatgt
    10981 cgaacggata tttgtcatgg aaccagaagg tcaaatcaag ttgcaaaatt tacttaatca
    11041 gattgatgaa cgctttttat ttgcagcaga aacgatcatt gatcatgcgg aaactgtttt
    11101 gatggaaaag ttgaatgaac atgtattgat cgctttgacc gaccacattg ctttttctgc
    11161 ggagaacatt aataacggta tcgtcatccg caacaaactt ttaagagaaa tcgaagtgct
    11221 ttacagtgat gaattcagta ttgctcaatg ggcagtagag tatctgacaa aagagcttgg
    11281 gattccatat acttatgacg aagcaggata tatcgcaatc catattcaca gcggacgaag
    11341 cggtcggaac aataaccatc gcagtatccg tgaagtgacg attgtatctg acatcatcca
    11401 tttagtggaa tcagaattgg aaacagatat ccattcagaa ccattttcac tgaattattc
    11461 aagactggtg aatcatttac gactgcttct acaacgaacc catgcgcaac aatatgctgt
    11521 tttagacacg gaaatcgtag aaatggtcaa acgaaaatac ccagaaagct ataagatttc
    11581 taaaaaaatc cgtgtgttgc tgaccaaaga ataccagctc gcgatcacga aagaagaact
    11641 gggttacttg gccatccata tcgagcgttt aagaagcgca atcgtacaaa caaatgttaa
    11701 caatcatgag gaggaaaaaa attgaaagca tatctacaac gaatgggacg ttcccttcaa
    11761 cttccagttg cggtcttacc tgctgctgct ttactagtag ggatcggaaa ctggtgggca
    11821 tcttatagta acgacattgt cgctcatttt ttacaagctg gcggtaacgc agttttaggt
    11881 caattacctt tgctgtttgc cgttgggtta gcactaggga tgtcagtgga caaatcaggt
    11941 gctgctgcct tggcaggttt ggtcgcattt gaagttccag taaatgtttt aaaaactgat
    12001 tcagtagcta ctttattgaa tatcaaacca gaatcagttg atccatcttt tgctcagatc
    12061 agtaacgtat ttattggtat tattgccgga ttgattgcgg cagctcttta taatcgtttc
    12121 cacgaagcaa aattaccgat ggctttatct ttctttagcg gcaagcgtct agtgccaatc
    12181 ttggctgcct ttgtcatgtt gctgatcagt gcagtgctac tgctcgtatg gcctccggtt
    12241 tactctgctt tagtttcttt tgctaaattc attttgagtt taggctgggg tggtgcaggt
    12301 ctttatggct tcttcaaccg tttactgatc cctacaggat tgcatcaagc aatgaactcc
    12361 gtgttctggt ttgacgtagc aggaatcaat gatattggta aatttttggc ttctgaagga
    12421 acaaaaggcg taacaggaat gtatcaagct ggatttttcc caatcatgat gttcgggctt
    12481 ccagcaggag catatgctat ttacagaaat gcacgtccag aaaacaaagc aaaaacagct
    12541 tccttgatgc tagcagcagc ttttgcttca ttctttactg gtgtgacaga accacttgaa
    12601 ttttcattta tgttcgttgc ttggccatta tatgtcttgc atgcaatttt cactgggatt
    12661 tctttagcag tgagtgcatt cttccattgg acagcaggat ttgcctttag tgccggattt
    12721 gtcgattact tcctatcttt gaaaaatccg attgcgaatc agccattgat gttgatcgtc
    12781 caaggattag taacagcagt gatttactac tttggcttta actttgctat caaaaaattc
    12841 catctgatga ctcctggccg cgaggaagca gatctttcag atgacgatac tgcaacgact
    12901 aattcagaca ataaatatgc ggcacaagca agcaaaatct acgctgcatt aggcggagcc
    12961 gacaatgtaa cttcgatcga taactgtact acacgccttc gtttgcaagt caaagataca
    13021 ggcctgatcg atcaaaataa aatcaaagcc actggcgtac ctggtatgaa gatcatcgac
    13081 ggaaaaaatg cgcaagtcat cgtaggtaca gaagtacaat tcgttgcaga tgagatggca
    13141 aaactacatg gtggtgctgc agcacgacct gcacaaacaa acaccgtggt taaaacagaa
    13201 acatttgccg gtgaaacgat cgaacaagat atttacgcta tcgcaaatgg gaaactgatt
    13261 ccaatcactg aagtttcaga tgatgtattc gcggaaaaaa tgatgggtga cggctatgct
    13321 gtattaccag aaaatggaga aatcttctct ccaatcgctg gtacgatcac aaacattttc
    13381 ccaacgaaac atgctgtcgg aatccaaaca gatgctggta tcgaagtctt gcttcatatg
    13441 ggcatcaaca ctgttgactt aaaaggcgaa ccattcactt tatatgtaga agaaggtcaa
    13501 aaagtcgcaa gaggtcaatt gattgcttta gttgatcttg ccgctattca atctgcaggc
    13561 aaaaacacgg atatggtcgt tgtattcaca aatggcgaca aagtccaaag cttagaaatc
    13621 gaacccgcac gtgatgtaaa agcaaatgat aaaatcggct ctgtttccaa caaagcctga
    13681 gccatcgtct tccccagact tttttatcga taaacaaaca ggagctgaga caaaaatctt
    13741 gtctcagctc ctttttccga ataaaaacgg cgttctcctg ccaactccgc ggtaataagt
    13801 ccagctaaac gaaacatatg aagagctatt ttttatttga ctcttcttat tacttgatgc
    13861 agaacagctt tttcacaaaa tttttcttca tactcaaaac taatcggctt tttcacaacc
    13921 tctttataca ttattcctga tccaatattt cttttaatgc tgcttcaaga gaagttaatg
    13981 gttttcccaa tactttttct aaatcatcag aggaaatagc taactgatcc tttttaatat
    14041 catgttggat cgctaaaaac atgtcagctg cttcttgagg gaatccggct tcttttagat
    14101 tttcgacaaa cgctgcatca cttgcttcaa taatttctaa ctctttacct gtcgcacgct
    14161 ctaatgcctt ggctaattct tcatagtcag ttagattgcc ggataattct aagatttctg
    14221 gagagtcact ttctactagt acttttgctg cagcttctgc atattcacgt ttcaatgccc
    14281 aacctgtttt tccatttcct gcagcataaa cgaattgacc agtttttaaa gcctgcccaa
    14341 tgataggtaa ttcattctct acataccaat tattccgtaa aaatgtatgg gaaatacctg
    14401 aatccttaat cattttttca gtgaattggt gatctggcgc taatacactg atcgagtgat
    14461 cggcatctgc aaaacttgta taagcgatat aagatacccc agctgcttgt gctgccttca
    14521 ctacattctt atgttcggct tgacgatttc ctggaacgcc agagacaaaa agcaatcgat
    14581 ctattccttt caacgcttct ttcattgagt ctaaatcatc ataatcacca atacgtatat
    14641 taaatccagc ttctttcagt gcttctcctt tttcttcact acgtactagt acatagattt
    14701 cattttgtgg aaccatcttt tttaagaatt ccagcgcata accaccaaaa cctccagttg
    14761 ctcctgttac taaataatgc atatttgcca ctccctattc tttttatttg ttaagattta
    14821 cagctgtaca tttataaatt acacctttat cataaagagt gtggtaagat aagtcaagca
    14881 aaaaaaatga aaggatgaca actgatgaag tattctctgc aatttagtga tgcaatccat
    14941 gtacttgcct atattgaaat gtttcaagat acccgatcac tttctagtga gatgattgcc
    15001 agtagtatcg aaacaaatgc agcaaatgta cgtaaaatca tgagtcagct caaaaaatcc
    15061 ggtttgatct ttacaaaaac cggaaaaccg cagccttccc ttgccaaaag tccagatcag
    15121 atttctttac tagatgtcta tcgcagcatc gaaggtaata cacagcttat ccaagtcgat
    15181 ccaaaaacaa atccaaattg cgtcgttggt gcgaatatcc aagaagcttt agaagaaagc
    15241 tacgctcggc tgcagaaaaa ggcagaagaa gaaatggcta agatcacact tgatagtctg
    15301 atacataaaa tagccgtttt ggaaaaagaa aaaagaccag aaaacacagg cctcgtagag
    15361 agatttttat aattctctct actgtgcctg catttttctg atcggaatcg tctacataaa
    15421 ttcttttatt ctccggggga caaaagcctt gtcatgcccc tttttcctct ctaatgctca
    15481 ggtcaaagcg ctgaagtcat gacgtcttga taaacggtgt tcaagtagct gaccctcggc
    15541 attagttctg aaaaatgcaa aatatggaaa gctatttccc atttttcctc tctaatgctc
    15601 aggtcaaagc gctactttca cgacctctat attatcatgg tttattgact accggtatcc
    15661 agatttctcc catatatttc ccgttggtaa ctcccatttc gactacagca tttggacccc
    15721 caacataggc gtaatcttct acttctctta aaacatgccc aaaggccgta ttcgtcaaat
    15781 catttcttaa ttcttcaggc gattctgcta aagcgcttac aacaagatac gttccttttg
    15841 ggaatgggat gattcgcgta gtgtttggaa catcctgact cgtttgaaca ccgacatagt
    15901 acatcatttt cccgttatag ggttcgttga ctgtaaagaa ataatgattt tcagcagctt
    15961 gtttcaatgc atctattgtt ccattaccga taactttttg ctcaaatgct tgtttctctg
    16021 cagccaaacc gacaaaatcc gtattgctac tcttcaattc cacaccaata cccgtcaccg
    16081 taaaatctgg tttttcttcg atcctatact ttgccatttc tcccaccctt tctattatat
    16141 taagttcatc ttacataaaa ttaaagggaa atgacacgat tacgctcttt tttctaggga
    16201 tatttttatt ttttaactat ttttttgctt tcactgcaat ccaaatctca ctgtaaacat
    16261 tactgaaatc ctctccccat tttgtaaaag agatctcggg agcttcgact aacccataat
    16321 ctgaagaagg aagccattct gcatagattt tcccccaagt atcttgtaaa gtttggggaa
    16381 atggcccttt attaggaaaa atggcccaag tgtgttcttc tatagcaagc atttctaaat
    16441 cagcgtacgg attttctttt gtcgtagcaa agccaatcat gtgcatcaaa ctgccctttt
    16501 cttccaagcg gtctccatca aatccataag aaacgttgat tacttgattt ggatataaat
    16561 ctcctaactt atgcatctct tccctttgag tctccgtgat cgtctgcgct aacttttgta
    16621 tttcttgatt gactccttca aatttgacag gaactttttt cgccacacct gccacataaa
    16681 actgttcttt cttttcgata cgaaattcca tcgattttcc tcctctgaca tcaataaaaa
    16741 atgtcaagcg tggaaaagat ttttgtatgc cgtatctact gatttctgaa ggcagatatc
    16801 ctgaccaatc acgaaaagct cttgaaaaac cttcgactgt ttcatatcca tatctaaacg
    16861 ccgtttctgt cactcttgat ccatctagaa gatcgcgatt agccaaagcc aatctacggt
    16921 ttttgatata gtccattagc gacatccctg caataaacgt aaagatgcgt tttaattgat
    16981 attcagagat tcctgtattt tcggctatta ttttatagga aagtccttct gtcaaatgtt
    17041 cttcgatgta atcgatcaat tggttcagat ctttaagcat atttatcttc ctccttgatt
    17101 gcctttttat catattatca aagaaagtca attacttgat gaatcaggaa ccaatttagt
    17161 cagatgtaga aaatgttgta tggatctaaa gaaaattctc aagcagcgtt tcgtaacgga
    17221 taattggtat tatctgccta tctatgtttt acctttagaa aaataaattt tggggaagac
    17281 agattctaag taaacaaagc ggtaaaaata tcttttattc ccttagttaa tccgcttact
    17341 acctactgta caaagcaaat tgttgttcaa actgctgatc agaacgctgc ttggattttt
    17401 ctttgcgata catcatacct cttttatcaa ttggaacaat tatttatttc taacaaaatc
    17461 acttcatttt tgtcagataa ataaaaaaca aaaaaagttc catctttaaa acacgctatt
    17521 cttttacttt ttctcacatt ctctaagaaa agaaaaggag aatgaatttt tgacaattcg
    17581 agcaaaagtg attatcaaat atgtaaaatc agctactttt ttcttaaacg tttctttata
    17641 ctaaatataa ataagtgttt catgaaagga gaactagatg aataattggc ttgagtattt
    17701 tcctgaaaac gttttggaac gcggttacag ctatcatctg cacggttttg tccgtcattt
    17761 gaactataca agcaagtact tgtccgcaac agtttctggc acggaagatt ataaggtagt
    17821 gatcacttgg gatgaaaaga ccaacatgac ttgtgattgt ctatatgcca tagaaggaaa
    17881 aaaatgcaaa cacatggctg ctgtcttatt cgcttacgaa gaacgtccaa taaaaaaatc
    17941 caactactca ctttccgaac tctcgtccct tgtttcctcc gctagttcct ctcttgtacg
    18001 ggagctttta acagagattc ttatagaaca tccgcacttt atcgaacgct tcaaagttaa
    18061 gatgccattt catgcaataa attattcaga taaattaaca actatcatcc ataaatacga
    18121 tcatattatc aagaaaaaca aaaacaggaa aacagcgaag ttcatcatgg agatgcgaaa
    18181 gttcatccaa gaagcagttg aatcgcttat tcagcaaaat gcctatcttc ccgcattcga
    18241 attgatcaat gaagtgattg ctactctcga aacattctat tgggagcctg aggatgaacg
    18301 aacccttctt ctgatagagg actgttatta tttatggaaa gaattattag cagaagcacc
    18361 tcatgcagaa aaaaggcaaa tgttctcttg gttcgtctgc caagtcgatc atactgacgc
    18421 ctcttattca aaacgctact ctataaaaat cctgaaagaa gactttcggg aaaaagaatt
    18481 ttctaaccaa aagaaaaaaa tagataaaaa actaaagaaa cggtaaagaa agacgatttc
    18541 aatgaaaaat agcaagtaaa cgataacaac catcctaaat ccacaagaaa tacagcagac
    18601 cttgctttaa aaacacgaat catgcaaagg atgaagtaaa gaagacttaa cgcgtaccca
    18661 atattagtca tttgactatt aggtacgcgt tttgttttat aagtcatgac aaatttcctt
    18721 cgttgctgga tagattttcc ggcattgttg atagatttta tgatactttt ctacattttg
    18781 taagagaggt tccgctgcat ctgtatattg gataaaattc tgacaacaac tttcaggtgt
    18841 gtcgaaccac cctaacccta gtgcagcaat cattgttgcg cctaatgcag gtccttcctc
    18901 cacacttaaa caatagaccg ttgcatcgaa aatatcagct tggatttgta gccatgcaag
    18961 atttttcgcg cctcctccca ccgaaacaat acgtgtaaat ctgcgacccg ctagttcttt
    19021 acgtttcaat cccaccattg acaaatgctc attaaaaatt tagaatattc acaagtttaa
    19081 cgacaattat gaaaatttat gtcgtgctaa aggagttttg ttattggatg aaaagttaga
    19141 tataaaaact gcgatcaaag acacgttacc taccgttttc ggttatatcg gtattggact
    19201 tgcatttggt atcgttggga aagctgccgg atttcatcca ctagtcgtca cgttgatgtc
    19261 cctgctggtc tatgctggtt ctgcccaatt tatcacagtc agcatgcttg ctagtcacag
    19321 cccattgctt tccatcgttt tctcgacctt tctagtcaat tcccgaatga ttctgatgag
    19381 tatgacgatt gctccttatt tcaagaaaaa tcggctgctt caaaatctgc tgattggcac
    19441 attgctgaca gatgaaagtt tcgcactggg aatgaataaa ttgaactata ctggacaaaa
    19501 gttaaacttt cgttggatga atacagctaa ttggatttct tatttgacgt gggtgggttc
    19561 ttctcttgtt ggcgcacttt tagggaattt tattactgat ccgaaaaagt ttggtttgga
    19621 tttcgccatc gtcgctatgt ttatcgggtt actttatctt caagtcattt ctgatagaaa
    19681 cacctctaaa cgattacagt tgatcctgat tggtctcact ttgattctgg tatatgtcgg
    19741 actgattttt atcccaagca acttagtgat tgtagttgta acactgattg ggtgcggatt
    19801 gggggtgtgg atcaaacatg ccttcttttg agtttacatt gctgactatt ttaggttgta
    19861 ctttagcaac ttggctttct agggtcctac catttgtctt actgaaaaaa ttcgatttac
    19921 cgcaaccgtt gcttgagtat ttaagttttg tcccgatcgt cattatgtct gctttatggt
    19981 tcagcagtct atttacccaa aatatcggac atctgccgca gatcaatctc gaaaatgctt
    20041 tggcttcagt tcctacactt ttagctgcta ttctttcaaa aagcttattg gtgatcgtct
    20101 tggcaggaat tctttccctt tcgttgattc gcttattata aataaaaaaa caagagctta
    20161 tggcaaatta ctgtcatgcg ctcttgtttt tatcaaagtc aaataagaaa aaaatcggcg
    20221 tattcttgct tatccgttga acggaccact aacaacgact tttcctaaca tatgtcctgt
    20281 ttctacgtct ttggttgctt gtttcaagtt cttcgcattc atcccatctg aatagacctt
    20341 gctcaatgta ctgcggataa tcccttcatt tgctaaagca gcaatgtgcg ctaaagcttc
    20401 tccttgcgtt tcgatttcat agttatagtc tgttttagcg aacatatact cccagtcgaa
    20461 gctgatagat tggtttttcc aaacacctat atctaacggc tctttgatcc ctacgatcgt
    20521 tcccacatgt ccaaatggtc ggacaaggtg cttgatttga tcaaagtagc gggtaatatc
    20581 gaataataca gcgacatact ctacttgatc gattcctaat tcacgaaaac ttttacttaa
    20641 gtcgtgatga taatcgattg gatagtctac acctgttttt ttcagccatt caaaattctt
    20701 cggacttgca gtcgcgtaga cttctaggcc agcccaatgc gctagttgat tcaaaatcga
    20761 accgacgccc ccggatccgt tgatcactaa gatttttttc ccgcgattgg cattttcttc
    20821 tggagttaga ccaaattttt caaataacaa ttcataagcg gtcaatgagg tcaacggcaa
    20881 ggctgcagct tcttcatctg aaagattttt tggtgcaaga gcgacaatac gttcgtcaac
    20941 tagttggtat tcttgattgc ttcctgctct tgttgttgta cctgcgtaaa aaacgcgatc
    21001 gccgacagaa aatttttgca cttcgtcacc tacagcaaca actttcccga ctccatcaaa
    21061 acctaagata cgtaaagcat ttcttatccc gttatcttgg cgaagtttcg tatcgacagg
    21121 attaacagat actgcgttga cttttaccag aagatcccgt gaactgggta caggtatctg
    21181 ttctttttca tcaataaagc tttttggatc atcgatcggc aacccttcat aaaaaccgac
    21241 taccttcatt aattcctttt ctgacatacg aattcctcct tagcttcatc aagttggagc
    21301 atccatacag tgttcatttc aatatatata gtatgctatt tgttccacct tttttattca
    21361 tcataattat tctcttactt aaagtaaact atttgcactt ttttggttaa aaaagaggtt
    21421 gcgacaagac ttttgtcaca acctcttata aacggtgttc tcctaccaac tcttcggtca
    21481 caagtcaaaa tattcatcaa acatgagaag ctgttttttg aaattgctcc ttgtgactca
    21541 gagttaaacg gcaggctcac aacctctgat ataaacggtg ttcaatcaac tgaccctcgg
    21601 tattagctca aaaaacgaca aaatatgaag agctattttt gtttggctgt tcttattact
    21661 tgatacagga cagctttttc acgacctcta attcacggtg ttcaagcaag aaatcattgt
    21721 tcactgaaaa gcgttggatg ttctttttca aaggtctcta agatctctcg tacttcatca
    21781 gtagatttcg tattcatcaa ctgaactcgc aagtcatttg ctcctggaaa tcctttgata
    21841 tagattttaa agaaacgatg tagtcctgtg atggaacgcg ggatgatttc tgaataatga
    21901 tcttgcagat ctagttgcag acgaagtagt ccgatcagtt ctttttctgt atgttccctc
    21961 gggtcttttt caaatgcata aggattcttg aaaatccctc ggccaatcat gatgccatca
    22021 acgccatatt tctcggccaa ttcttctcct gtctggcgat cggggatatc tccattgatc
    22081 gtgattagtg tttgtggagc gatttggtca cgtaaagcaa tgattttagg aatgacttcc
    22141 caatgtgcat ctactttact catctcttta cgcgtacgca aatggacaga aagattggct
    22201 atatcttgat gaagtaggtg actgatccat tcttccatct cagacatttc cgtatagccg
    22261 atacgcgtct tgacgctgac aggcaaaccg ccagctttag ctgcttcaat caattgtgcc
    22321 gctacttctg gacgaaggat caagccactg ccttttccac gttctgctac attagggact
    22381 gggcagccca tgttgatatc gattccttgg aagcccattt ctgccatagc aatgctcatt
    22441 tctctaaaaa attctggctt gtctccccaa atatgggcaa ccatcggctg ttcatcttct
    22501 gtaaatgtta atcttcctcg tacactgtct tttccatctg gatgacagaa actgtctgag
    22561 tttgtaaact cagtaaagaa gacatccggt gctgctgcat gctttacgac atggcgaaat
    22621 acaacatctg ttacatcttc cattggtgct aaaacaaaaa aaggctttgg cagctctttc
    22681 caaaaattag tagtcattta tttgttactc tccattctat caagcagtga agtcgcaatc
    22741 tttctcaaaa acattgtcat tatactagga aacaaaaaaa gaagcaaagt gaacagctta
    22801 aaagatgttt ctgattgagc aaaaaaaaga ctgtgacaaa aatcttatca cagtccattt
    22861 tccggaataa atggtgttca aaagcttgca tttgcggtaa taagtccaac caaacgaaaa
    22921 ataggaggag ctatttttgt ttggctgttc ttattacttg atgcagaaca gctttttcac
    22981 aacctctcca ctaaacggtg ttcaatcagc tgaccctcgg tattcgctca aaaaacaaca
    23041 aaatatgagg aactattttc ccgtttgttt ctctaatact caggtcaaaa cgctgatttc
    23101 acaacctctt ttctaacttc tcaatcctct tcctttattg atcaaatacc aagtaacggc
    23161 gtacaaaaca acgatgaata acacaagtac gatcatcgat gttgctactg gcacatcgat
    23221 cgttccaagg aatccgtaac ggaaaccgga gatcatataa acgatcggat tgacttttga
    23281 aacagcttgc caaaagggcg gtaacataga gatggcatag aaaacgccac ctagataagt
    23341 taacggctgc aagacaaatg taggcacgat cgatacatca tcataagact gagcaaaaat
    23401 cccgttgagc agtcctgcta atgaaaacaa gattgccgtc atcaataatg taatgatgac
    23461 catgaaccat gaatacacat gaagtggtac aaagaacaag gaaatgatcg ttacgagaga
    23521 gccgacgaga atactgcgac ccacaccacc aatcacaaag ccccaaataa tcacatgcgt
    23581 aggaacaggt gctaccaaga tttcttcgat atttttctga aatttttgag agaagaagga
    23641 cgaagaaaca ttggcatacg aactagtgat agcagacatc ataatcaaac caggaacgat
    23701 gaattccata tatgaaaaac cacccatgtc accgatccgc ccaccgatca tttttccgaa
    23761 aataacaaaa tacaaggatg tcgtgatcac tggcggaacc agtgtttgga cccatatacg
    23821 caaatagcgg ttcgtttcct tgatagctaa actttttaat gcagtaaaat aaagattaaa
    23881 catttttctc ctccgtatga ttattttctt ctgtgatttt caagaacagt tcttctaaac
    23941 gattcgactt attcctcata gaaagaactt tgattccttg tcttgtaagc tgatcgaaga
    24001 ttccgttcac cccttgattt cgttcaactt cgacagcgat tgtctgctca tcttcaaatg
    24061 tacaagcata tccttcaatc acaggtttgg tatcatatgg cgctaaatca aagataaatg
    24121 tttcaaattg cagttttgac agaagctctt tcatacttgt attctcgatc agttcacccg
    24181 attggatgat tccgatgttg cgacaaagca tttcagcttc ttctagataa tgcgtcgtca
    24241 aaatgatcgt tgtaccattt tcgttcaatt ctcgtagaaa ctcccacatc tcgcgtctca
    24301 actcgatgtc aactcctgct gttggttcat ccaagatcag caaacgtggt tcatgcatca
    24361 atgccctagc aatcatcagt cttcgcttca ttcccccgga aagcatacgt gcacggacat
    24421 ttctcttttc ccaaagattg gactgcttca aatatttttc gctgcgtttc atcgcttctt
    24481 tgcgagagac accgtagtag cctgcttgat tcacgacgat ttgctggacc gtttcaaaag
    24541 ggttaaaatt gaactcttgt ggaaccaatc caatctgttg ctttgctcga actagatcct
    24601 tgtccagatc ataaccgaag acattcactt ttccagatgt tttattgact aaagaagtaa
    24661 taatcccgat cgttgtagac ttcccagctc catttggccc taatagcgca tagaaatctc
    24721 cttctttcac cgaaagatcg attccccgca atgcttcgac cccacttcca tagatctttt
    24781 tcaaattatt tatttcaagc gcatttgcca tttatttcct atctccttat agacatgatt
    24841 cttaattgta tcatggaata cagcagatga aaaaacaact tggcttccac acaaaaacac
    24901 acctgctaac aaagaggaga tgtgttttct agttcatgat catcttcgat agaataacta
    24961 tctaaacaac tctggaactt ttaaaatcat aaaagtaccg acagcaacta ctacgatgac
    25021 atatagaaga tccttataac tgaggttctt gtctttttta ttcatgttaa gctttcctcc
    25081 gtccttttat cgaaagcttt tttcttttat tttaaccgaa ataaataaaa tggaaatagt
    25141 tattttcaat ttctgttttc gctgtttgtt ttacggagaa ctttgccatg gaacgtgcgt
    25201 ctcgtcgctg atgctaagtt ttttcgataa aagctgctag aaggaagaca gcgtggttta
    25261 ttttgtatcg tcttttgcta aatcttccaa gatcatctgg acagcagact cgttcccatt
    25321 gaattctgcc acttttttgg catcaatgta cttcttttga taatcgtctt tttggaccca
    25381 cgcatcatgc ttcgtttgat aaagttaatc aaacggatac cactgacgct gttcatcgaa
    25441 caacaaactt tctttttggg cctgttcaac tatggattta ggataattca aaactttcag
    25501 caaggcaatc gcatttcggg tccttgaagg tccttctttt aatttgaaat caaaactgat
    25561 tccttttcct tctgttactt gttcttcaaa gtggacattc tcacaataat tctttaaaat
    25621 ctctgtcaat tcgatatcat gtgtggcgac aaatgctaaa gatggatact ccgcaagcca
    25681 ccgaacgact gaagcggaag aagcaatccg ttcgatcgta tttgttcctt ttaaaatctc
    25741 atctacgaag cagtagcagc gttctttgga agccacttgg tccagcaaac gtttgatcga
    25801 tttgatttct gaaacaaaat aactgtcgcc ttcaaataaa tcatcttcga ttgccatgga
    25861 agtcaacaca tgtccaggtt gcagggtaaa ctgttctgca atcgctgttt ggatcgtctg
    25921 tgctagaata cagctgatgg ctatactttt gacatacgta gattttcctg atgcattgga
    25981 acccgtgact aatgtattct tctgccagtt gactggatta actaccgctt cttttaacaa
    26041 tggatgatag atatctttcg ctgtcacacc gccctcagta aactctggtc ggcaagtgat
    26101 cggcatatag gtgcgataat tcaaaacggc tgctgcaact tccaattctc ccagcaattc
    26161 ccacagcttg atggcttcag ttgaatgctt ttctaattta gtgagaacga aatgatagga
    26221 gataaatggc agcatgaaca tgatgttgac atattcaaaa atcaattctg cttcactccc
    26281 gctcttcatt cgaaatgaaa aacctaattt agggatgtct cttaatggtt tagtttgctg
    26341 tttcagctct ttttgaagtg gtgtcgtcat ttttgctaac tgattggcgg ctgaaatcgt
    26401 tgaaaccaaa taactcatgc tattcagctc tgtttctagt gtttgtttct tcactagata
    26461 atagaccgta ttgaatacta agccaccgat tgctagatag attcctagta cttgccctaa
    26521 aagaagcaaa cctacaccca ccagcggaag caagccaaga aaaataaata aacctacgcg
    26581 tccaatcttt ttactttttc catccgctag atattgtttt gcaaaattat gatctttttt
    26641 tcctaaacga gcgaattgat attggattct ttctctcagt tgaggatttt cctgataaaa
    26701 agcaattagt ttttctaact gataatcttc tccaaaatca aagctacgta aacgctgata
    26761 caacgcttct gaacctacac tagaataggt actgttgatc ccttcaaata cttcgaacat
    26821 atccaagtca taccaagtaa gatcgtcgat ttcactatcc catgaacgga attttttctc
    26881 cgtgagccac gcatccttca aactttcttc tttatcaaat ctcggttgat aaggaatttt
    26941 tccccaatta ctacgaactg tttcctttac tttcaaacgt gaaaaaatgt ctaaaacaac
    27001 taataaaata acaactgcaa taataattaa aacgataaat tctctttggc ccatatccct
    27061 ctccgttcct tgatttgtta gttttagtat agcactgttg cgctatttga aaagggggta
    27121 caaaaataac tgtcttcgtt acctaattcg tatcaatcac accaaaataa aaacaccttc
    27181 caaaaaagaa gatgtcttta aaacgagata caattttttg tcattcactt caggtaaatt
    27241 agagccaatt aaaccctccg caacttgacg gagatggaga agatgccccc gtctaatcta
    27301 gcggtcatct ctcctcccat tccttccacc aatttttttg acaggtaaag cccgattccg
    27361 ctagattccg tatttgtgcg gctggtattt tcggtataaa aacgctggaa gactttttca
    27421 acagaggttt gcgctcctgg tttgatagga ttggccactg ttaatcgaat gaatgaatcc
    27481 tcttttgaaa atgtcacctt tgcttgtcca tctgcataac gcaataaatt ctgtatgata
    27541 ttttgcagca ctcgcagcaa catgagcgga tctgctaata cagttgtatt tatcgagtgt
    27601 tcagcgaacg ctacctcgat atttttctca gaaaattgtt cataaaaaga gaaaaatact
    27661 tcttccacct ctttagaaaa agaaagcgta tggagatcca tttctttttg cttcgtctct
    27721 attcgagcaa gatcataaaa ctgatccgtc atactgagta atcttgcaac agattgtttg
    27781 atgatcgtta aatacttctc ccgtttctcc gtatcctcta cctgttccag taattgtaca
    27841 taaccgttaa tagcagtcaa aggagttctg agatcatgag aaaggccgac gatcgatagt
    27901 ctgatgtttt cttccatttc ttgaaatgct tgtccttttt gttcattttc atccacccat
    27961 gtattcagtg catctactag gtccattaga ttcttttctc gaaattcgac tgaaagacga
    28021 ccaccatatt cttgtcgttc agaaagagtg gcgattttct tagttaatct cttgatttcc
    28081 ctttgcagga agaaaataaa acttcccata aagataacaa cgagaagcaa cagccactta
    28141 atcaaatcta aaccccactc cccacaccgt atgaatatac acagcatgtg cctttgctag
    28201 tttccctcga agattggaaa tatgcatatt cactgttttc tcactatcaa aatatggttc
    28261 ttgccaaact gtttcataaa gatttgctcg cgaaaatact tttttcggat gttctaaaaa
    28321 aagcttcagc agatcgaatt ctcttcctgt caaatggaca gccacaccat tcacatttac
    28381 atccctcgac tctttgtcca gtaagatttc cttgtaatag atgcgttgcg acagatcttt
    28441 tacttggaca gaagtctgat gacgaagttg gatgccgatt cgtaacaaca gttcttcgat
    28501 atcaaatggt ttcgtcacat agtcatccgc tcctgctgcc aacaaggaaa ctttatctct
    28561 ttgatcgctt tttgctgaaa gaacgatgat cggaacattc gatgtctgtc ggatttctgc
    28621 taacaatgct tcacctgaaa gccctggaag catgagatct agaaggatca aatcgacagg
    28681 atatgtgctt aacaataatt ttccttccgt acctgaataa gcatcaagaa gtttgtatct
    28741 ctgttcaaga acctcctcca gtaaagaatg aacagcttca tcgtcttcga taatcaaaat
    28801 agtttccagc aggaacacct acttaatgtc agatttttgg aaaataaaca ttcctagagc
    28861 tgatgatacc acgattgtta ctagactgac cagaatcatt ttcggtgctt gcgaataagt
    28921 tgcttgttgc gcaaagtccg tatacatgag ccacgtttcc gtaaaccact ccgttagaaa
    28981 ttccaagcct ttgatttttg cgaaaacacc gggaacgaag gccgttccca tgatataaag
    29041 aaaagaaaga agcaaactga cactggtact tctagtgatg aatgtcaaag ccactggaac
    29101 agataatgtc gctaatatca gcagaagcaa tacaggaaat acttttagaa cataatttcc
    29161 atagtttttg attccctcaa cttcaccaaa tccgaaagca agtgtgtaag caatcatggc
    29221 tagccccgta atcaaaacca cgccaagtgt tgtgatcaaa agcgtaacga gaagtttcga
    29281 cacataataa gtcattcgat tccgtcctaa agataacgta ttgcgaatcg taccgttttg
    29341 aaattcttcc ccaatataaa agcacgcaaa tgctgcgaaa gccagaagaa tccatgcagc
    29401 cattttttcc accattaaaa tccctgttgc accgttgatg actgtatccg ttgcttggtt
    29461 taattcattg ccgtattttg tatgcatata ccattcgttc caagaataaa aaagcggaag
    29521 tacgaccatc agtcctagtg agacccacat tttacggctc ttccatactt ttattttttc
    29581 agcagttaat agattaaaca tgtggattgc ctccagttaa ttgtaagaaa taatcttcca
    29641 gtttttgccc aactaggtgg ataccatcca caggaacttt tgcctctacc aatgcttgat
    29701 tgatggctgc tacttggtca attccttcaa aaagctggat aacacggcta gattggacaa
    29761 aataatccct ataaccaaga gagtcgagaa ccgttactgc ttgttccgtc gccgaagtgt
    29821 caatttttat aaattgacga gattcttgtg ccaattcttc tttcgataat tctttgatca
    29881 agtgtccttc atgcaaaata ccgtagtgag tggcgatctg tgacaattca tctagcaagt
    29941 ggctagaaag caagacggtg atgccccgtt cttttaccaa acgttggatg atttctcgca
    30001 tttctgccat ccctgctgga tccatcccat tcgtcggttc atccaaaatc aaaaattctg
    30061 gattcgtgat cagtgcattt gcaatagcta aacgctggcg catacctaaa gagaaattct
    30121 ttgctttctt tttccctgta ttttccaatc gcatcatttt cagcaggtct tcgatttctc
    30181 tatccgacac accgccgttc gctgcttgga tacgtaggtt atctcttgca gttaattctg
    30241 gataaagagc aggggtttca atcgattgac ccatacgtcg tcttgctgcc tgcaaatccg
    30301 tcgttccaaa taattcgatc gaaccttcat caatcgagat caaacccata atagttctca
    30361 taaaggtaga cttacccgct ccattctccc caatcaaacc atagatcatt ccacgtttga
    30421 tttcgatcga tactttatct aatgctttgg cagcaccgta ttttttggtt ataccagttg
    30481 ctttcaagac cgtttcattt ccaaaatcca tacttatcct tctttcttat tgataagtga
    30541 agtatagttg acgggtataa agaaagcagc cagaaatgta taaagaaagt gtaaattttc
    30601 caattgaatt tcaagaaaaa tcagactgtc tcgcagacgt ggttgagttg tctgccaatc
    30661 aaagagcgca ccaaacagtg ctaatccaag tggactggcc accatggtaa tcgttgttat
    30721 cgttgacatc agacgtcctt gtatatgcgt tggaacttct cgctgaagcc agaccatata
    30781 aaaagcaaaa gaaaacatta atccttaaaa acggacttat gaaaaataat acatgccgtt
    30841 tgggatttac aattagctac caaataagag gttatgacaa aagacttttc acaatccctt
    30901 cttccgaata aacggtgttc tcctgccaac tcctcggtca caagtcacaa tatttatcaa
    30961 acatgagaag caatttttgt aaattccttc ttatttcttg aagctgacca cttctgtcac
    31021 aacctcagaa gcggataaat aatattgttt gatgatactt tatctttttc ccgtttgttt
    31081 atagatcgaa tgatattata gaccaagaat cctacctatt aacatagcta aaaacacaaa
    31141 aaaggcactt tccaaattgt ggaaagtgcc agaaaagtta ggattaaggt aactgcgctc
    31201 agcattgctt cgcccagtac gattctcgta actcgtgaac tcgaacgata atcgcaatta
    31261 acgttttgag aactgtgaag ctttacgggc tttcttaaga cctggttttt tacgttcgac
    31321 catacgtgcg tcacgagtaa gtaagccagc acgtttaaga gctaaacgga agtcaggatc
    31381 aacttctagc aatgcacgag cgataccatg acggatagct cctgattgtc cagcgtatcc
    31441 tccgccgttt acgttaacaa atacgtcata tgcgcctttt gtttcagtaa cagcgaaagg
    31501 ttgattgatt acttcacgca agtcagcatg tggaatgtat tcttcaacat cttttttatt
    31561 tacagtaatt ttgccagttc ctggtactag acgtacgcga gcaactgcgt ttttacgacg
    31621 gcctgtgccg atatattgaa cttgtgccaa tgaaattccc tcctattaga ttaagtttgt
    31681 gatgtctaaa acttctggtt gttgtgctgc atgtggatgt tctgctccac cgtatacgtt
    31741 caattttgta aattgtttgc ggcctaaagt gtttttagga agcatacctt ttacagaagt
    31801 ttcgatcaaa cgacgagaat ttttagcacg caattcgcca gcagtgattg atttcaatcc
    31861 tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc gcttttttac ctgttaattt
    31921 cactttgtct gcattgatga cgatgacgaa atcgccagta tccaaatgag gtgtgaaagt
    31981 tggtttattt ttaccacgta gtacagatgc aacaactgtt gaaagacgtc ccaatggaac
    32041 atcagttgcg tctactacat accatttacg ttctacttcg cctggtttgg ccatatatgt
    32101 tgtacgcacg ttattttcct ccaatttaag ttctgatgtt tgacatacac ttcgagtttc
    32161 cggggctctt tgtggggcaa acaataccat ttaacatatt acccgctaat ctagtcaatg
    32221 tcaacgtttt tctgcttgat tgaaaaattt atatgaaact ttacttcttt tctttctttt
    32281 atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa gaggctgtga caaaagtctt
    32341 gtcacaaccc cttattttga ataaacggtg ttctcctgcc aactcctcgg tcacaagtca
    32401 caatatccat aaaacataag aagctgtttt ttaaaattgt ttcttgtgac tcggagctga
    32461 acggcaggct tacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct
    32521 caaaaaacgg caaaatatga ggaactattt tgacgtttgt ttctctaata ctcaggtcaa
    32581 aacgctgatt tcacaacctc tttttcggtc aagttcaaca acagttttta cgcgtcgatc
    32641 tctggcgctt tgcccaaatg agcttggatc atccagatac gtttttctgt ggctgttttg
    32701 aattcgataa agatatcttg tgttggatcg tcgccttctt ctccagaaac ttcgattcct
    32761 ttttggtaaa gatctgctag ataacgatag cctgcaacaa gtgtttccaa acgttctgga
    32821 atagtacgat cccagcggcc aatttcatca gggatttttg tgttatctgc aaattcacgc
    32881 aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt cggatacttc atctaactga
    32941 gcgttcaaat catccatgaa ctcatccatc attgggtgca atgtaaggaa acctggtcct
    33001 ctcatgtacc aatgtgtttg gtgaacaaca acagacattt ggcttagatc tgcaactaat
    33061 tgatttaata cttctttggt ttgttggaat ttcatctttc ttgcctccta acattttctt
    33121 acacttaaaa taatagtaga ctttcaatga aaagtacaac aaaatcattt acctgagaac
    33181 gattttcagt tcgctttttt atccgtaaag ccaatcattt ttcagaatca gctaattctt
    33241 ctcgcagttg agcaaattgc tgataagtct gtgctaaatg cttttgtgtc gaaacaaata
    33301 atggatagat tttctgatat tttttatgat cagtttcttg tactccaact tgctctttca
    33361 attctatcaa ttcctgtgct tcactgatac tttggatctt tccgatgctt ctccagccta
    33421 aaatcacagc tcctaatgcg gatgcttctg tgacagtagg gaaaacaagc gggtaaccca
    33481 gtacatcagc catcatctga cgaaaaatcg gagattgagc aaacccgcct gtagcacgga
    33541 tctctgtgag ctgattttcc tggcaaactc cttttaaaat ccgataaagg ttgagacaga
    33601 tcccttctag aatcgccttc atcatttctt tttctgtatg ttgccgctgt aaaccgataa
    33661 aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc accaagtaaa tagggatgaa
    33721 aaatcagacc attggcaccc gctggcacaa aagcgatagc cgaaagcagt gcatcatatg
    33781 gattttctcc tttttcttta gcagattgaa cgacttcctg taaaaatgta tgccctgccc
    33841 aatcaaagat gccagcacca ttgctagtcg ctcctcccac tacccaatgt ttctgatcca
    33901 gaacataaca aaacgtctcc atttctggat ggaactgagg ctgagtagta ataaaacgaa
    33961 gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc accaaaagca cctaacccta
    34021 gattagaaag cggcccgtct gcccctccca aaacaaatga tatatcattt ggcaaaccta
    34081 gttctgctgc tgtttttgat ggtagacctg ttacttgata ggtggaagga aagacttgcg
    34141 gcaattgctc tattcgaatg ttcaagtagt caagcacttc ttctgcccat tggaattcat
    34201 ggatatcaaa atatccagtt cctgaagctg ttccgtagtc gctgatcagt tcgccaaaca
    34261 atctataaaa gatatagtct ttgataccga caaaataagc agtttttttg aataattcag
    34321 gttggctgtt ttgcagccac ttgattttgt tcaatggtgt cattggatga atcggcgtcc
    34381 cagtctgccg ataaaattct ttgccaagca cggtatattt cagtttttct gcttcgtccg
    34441 ctgctcggtt atctgcccaa gtgatcattc gagataacgg tgttttctct tcatccaaca
    34501 atatcaggcc atgcatcgca gaggagaagg agacaaattg aatgattgtg tctgaaggca
    34561 actgtttaat tacttctttt ataacggtgc agacaccttg aaagatcaat tcctgatctt
    34621 gttctgccat cccttgtgtt tcttggatca aagggtagcg aaaataagcg gatgctgctt
    34681 cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt ggttccgata tctaatccga
    34741 ttgaaacgtt cattttttca cctcaaattt tatgtatgta caaaaattta gtttaagctt
    34801 gcgtatcttg gttttgaaaa gggggagatg gcgtgttact ttattttatc attggttgct
    34861 gtatcggatc atttttatgt ttaaccgccc agcggattcc gttaggtcac tctattattt
    34921 atcctagatc tcattgtgtc aaatgctgtc gttcgctttc ttggtatgaa ttgattccga
    34981 ttctctcgat catcgtccaa cgatttcgct gccgctattg caggtgtcgg ttgcccttct
    35041 actatttgtt ggcagaagcc ttatgtggtg gtctttttgc ctggttcttt actttttctt
    35101 ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc tttgctattt tcgttgatgg
    35161 atttatttta cttcatggtc cattctcaca cgctattctg ttcttgggca attttatgga
    35221 ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt gctgttaacg tttatcgtag
    35281 gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc tggcgatact ctgttgatgc
    35341 tttcttggag tggtggcttg tctctagaag agttgcttca gatcttgttt cttgctagtc
    35401 tgtttggaat atccgttttt tctgtttact ttatctgtca taaaaaaaag ttggaaaagc
    35461 tgcctttcat tccttttttg agcagtgcgt tgctgattgt ccttcatctt aggtattgaa
    35521 aaaaggttgt gacaaacgac ttgtcacaac ctctgatata tagtgttctc ttaccaaatc
    35581 cttgtgactt ggagctaggc gacaggttca caacctctcc actaaatggt gttcaatcag
    35641 ctgaccctca gtattagctc aaaatgctgg ttttacaacc tctgatatac ggtgttccat
    35701 aagtagcttt ttcggcttct tatttcttga cgccccaatg tcgacgaagg aaacctgcac
    35761 gtccagaacc ttctcgataa agattgtaat ggagcttgtt tttcttgtaa taatcctgat
    35821 ggtaatcttc tgcaggataa aattcgcttc ttggttcgat ttttgtcacg attggcttat
    35881 cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc tgcaatattt cgttcttctt
    35941 catcattata gtagatcact ggacgataag aatcaccgcg atcagcgaac tgtcctaatg
    36001 cgtcagtcgg atcggtttgc tgccaataga tttccaccaa ctgatcataa gaaataactt
    36061 ctggatcata ttcgatctct actgcttctg tatgccctgt tgtgcctgtt gttacttgtt
    36121 cataagttgg atttggtaca tgcccgccag tataaccgga tgtcacagaa atgatccctg
    36181 gctgctcttc aaatggtttg accatacacc aaaagcatcc gcctgcgaaa actgcttttt
    36241 ttgtcatata aaatccccct tttttctcat cataccttga tttccaaaag gaggataacg
    36301 ttttgcttgt gacagaaaaa acggaaacta ttatatacgt gatacggctt ctgataaatg
    36361 ccaaaacgaa cgtacttgat caaaaacggt taaatcagga atcacatatt cagcagaagg
    36421 aagatttatg ttttcaccta ttcccaatac atgcatgtta ccagccaaag ctgcttgaca
    36481 accagcttct gaatcttcaa tgaccaagca tgcatttggc ggtacattca attgctgtgc
    36541 tcctttgaga aaaacttctg gatcaggttt tgcttttgat acttgcgtgc cgtcaataag
    36601 gacatcaaaa taacttgtca aattcgtttt ttctaaaatg aggcgtgcat ttttgcttgc
    36661 tgatcccaat ccgatcttga tgtttgtttt tttcaagtac tcaagaacag ctattgcacc
    36721 aggcaaaacg gatgtttcat ccattttttg aatcgcttga agatatagat tgtttttttg
    36781 ctcagcaaag gctgatttct ctttttctga gaatttctgt tccatttttc caaatgacag
    36841 caatcgctct agtgactcgg ttctggatat tcctttcagt tgctcgtttt ctttctcagt
    36901 gaatggaatg gacagctggt tagctaaaac cagccacgct tcgtaatgat aacgagctgt
    36961 gtctacaaga acgccatcta aatcgaatag tgctgctttg attttcatcg attacctcct
    37021 tgaaaatgaa cgacttgaag taaagatgcg atgtttttag ctgtgcgatg aagattatca
    37081 gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag gaaggatcgg aaaaacggcc
    37141 gaaatgccaa catctgctgc tttttcgctt cctttaccaa cacttccgca aatagctatc
    37201 acaggaacgc cctctggtac tcttctagca atcccaactg gcgcttttcc ttttagactt
    37261 tgtccatcta gacgtccttc gcctacgatt acgaggtctg cttgctgtac ccgtttatcg
    37321 aactccagta aatccaatac gtagtcgatg ccagagacta ttttccctga agcaaatgct
    37381 aacagtcctg cacccattcc accaccagca ctactgcccg atgcctcgat tacttgaggg
    37441 gcaaatctca tataaaaatc atgcatggct tggtcagcca ctgctaattc attttctttc
    37501 aagccttttt gtggtccgaa aacaaaagaa gcgccttctt ttccgcataa aagattagta
    37561 acatcagtaa tgacagtgat tttggcttta atcagctcaa taggcacgtt cgttttatca
    37621 actgtagcaa ttttacctag attttctccc agtgcttcta ctttttgatt atcttgatcg
    37681 taaaaagcat aacctagacc ttctgccatg ccgatgccgc catcgttggt actacttccg
    37741 ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca attgtcgtat cagttctcct
    37801 actcctcgcg tggataacct aagtggctgt tgttggttta gtgggacatc tttcaatccg
    37861 acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg aagcgtactg gatttctttg
    37921 tttttgccaa atgcattagt aacgactgct gtttgccgct tcaaccttaa actgtctgct
    37981 aatgatgaaa ccgttccttc tcctccatcg cctataggta gcagatcata ttcagcctga
    38041 acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg cctctaaggc tgtcagactt
    38101 tctttgaaag aatctggcgc aatcagaata cgcattattt tcccctccgt tccaagatca
    38161 gttctttttc cagctggtat tggtctccat tgacaaaaat aggtaatgtt tctttcgtct
    38221 ctttttttat tactatttgt ttttttgtca aaacaaatag caacctgtga tttttccaaa
    38281 taaaaggaaa agaaattttt tcccatgctg aaggaagtct tggagaaata gaaagagttc
    38341 cattcgttac tgtaatacct gaaaaaccaa atataactgc tagccatagt gctcctaatg
    38401 aagcagcatg aattccgtca tctgatgaat gcggatctgg tcctaaatca atcaggcacg
    38461 cttcttggaa taaatgatac gcccattcca tttcttggat acggcaagcc tctatggcgt
    38521 gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt ttcatagtaa tgcaaattct
    38581 tagaaacgat tggttgagaa aaatactcag gtaataagta taacagcatg acaagatctg
    38641 cttgcttgct gacttggagt tcatttactt cgctacgggc ataatcaagt aaaatagact
    38701 ggctgccagg acgttctttg taagtggtca aatcaataac tggcttactg agatacgtgt
    38761 catcttgcgg aatcagctgt tctttgttag gcactggcaa atataactta tctaaaaaat
    38821 tttgacattc tttcaaaaaa agcggatcgc cagcttgata tttaacagct aaggccacat
    38881 tataatgcgc cagatagttc gtatatgcat tattgtcgat atattctgtg tattcatctg
    38941 gaccaatgac tctgtgtatc tctaaatgat catcgacttt tacagctctg ctcagccaaa
    39001 aagctgctgt ttcatgaatg agcgtttttc cctttgtttc taaaaacgat tgatcctctg
    39061 ttgcttggac atactcttga acggcataag caaggtctgc actgatatga tgttctgcgg
    39121 cagctgaagc aacttcttgt cttgttccgg ttttgatatt caatgcagca aatttgggtg
    39181 tctcttcctg accagtgtgt gcgctttccc atgggaaaag tgcaccttga tagtgataat
    39241 ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg gtacagcagc aaattctttg
    39301 ctacttcagg aaactgatat aaaaagaaag gcaggataaa aatttccgta tcccagaaaa
    39361 catgcccttt ataaccttcg ccagttagtc ccttcgcccc tacactaaca cttggatcat
    39421 tgcggggagt cataatctgt aaatggtaag cagcgaagtc catcgctaac tgatcgaaag
    39481 aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa atctgtccaa taagacatcg
    39541 actgctctaa aatttctgta taactaacgc ttttctgggc ttgggcaata cttttcttaa
    39601 acgggtctgt ttgctgaaga gaggtagaga gcacgatgat cttctccagc gtaaaggacg
    39661 tattttttct gatcttttct gaaaaggaag cggtgatccg gcgatttttt gcttggaata
    39721 cacctgcttt attgaattta gctgcaatcc caatatcaat tttactttct gttgtctggt
    39781 aggatgcact gatcaaatcg tcaccaaata ctcgcagttc tttttcaacc aactgctgtg
    39841 taccaaaatt ggtttgctgt ccatcgatac ccgttttcac atctacttgg cagtcttcgg
    39901 tcaacggctt gatgaccact ttcagggctg cctgatggag attattttga tcagcaacac
    39961 gacaagtaat gacttccact ttttttcctt gagcagtttc aatgagcgca tagcgtttaa
    40021 gctctcccat ttctaaatct agtgcccgct cgtatgcaag aactttcatc gtctcaagag
    40081 aaaaatgttc accgtcgatt tttatttccc atctgatgac atctgggaga ttcactaact
    40141 cggctgattc tgctcctaaa ggtcggttat atacaccagc tgcaaacatt ccccttactt
    40201 gattccgata gtcttcctcc tggcttcctc tgataccaaa aaatccattt ccaatggtca
    40261 tctgactcgc atacttattg atatactcta aatcaaactg tttttcttct actttcataa
    40321 ggtaataact tctcctgttt ctgccgaacg atataaattt tccaccagat tctggatgac
    40381 atatccttgc cagccatctg caatcatctg agtctggtca ccgagcgccc gattcacaaa
    40441 atgagccata cttagttcat gtgggtcatt aactggcgtg gtcttttgta aggaaaccag
    40501 ctttccatct acatcttcga atagttcgcc tggatacaga ttagcacctg cctgatcgcc
    40561 acaaaaagcc acattcagtt tgtcttctct gatattcaaa gcaaacgaag tattcagttg
    40621 gatgatcttg ccgttttcta attccagtgt gccaaaaatt gcatcttcta ctgtgaattt
    40681 gcttggatcc catttcccga atttccctga attttttttc gtaccaattt tttggaagct
    40741 gtacgcccga acgcttttta ctttaggaaa tccagtaata tacatcgctg tatcaagcat
    40801 gtgaatgcca taatcgatca aaggcccgcc tccttgaagt tctttgtcga taaacgttcc
    40861 ccagcctgga acaccagacc gacgaagcgc attcgcttct acgtaataaa tatccccgag
    40921 aacatcaaga tgattcttga tcattgttgc ttcgtcagaa aaacgatgct ggaatccata
    40981 agccaaaatc tgcccgtttt tatcggctgt ctctgccatc tttcttgctt gatcagctgt
    41041 catagctggt ggtttctcgc acatcactga agcattagct tcgagggcag ccaatacatg
    41101 ttcgaagtga aagcgattgg gtgtacagac actcacgata tcgggagaaa tctcattcag
    41161 catttgtgta actgatgtat acgcatgaga aaatcctgta cgtcggcaaa agtcttctgc
    41221 tcgctggctg actggatcaa ccacagcggc caattctaag acatctgatc ttttttgata
    41281 ataagcagca tgtacttttt ctgctacttg tccagcgcct atgattgcta ctttcttcat
    41341 ttatttctcc ctcctttgct tatttactta ttgttattct ttctctattc tttctctaaa
    41401 tcatttaaat gacgcgctgt ttccagacag tttttcaagt attgcaatga ttcctgataa
    41461 attttcactt cattttctcc tcgcaaacga cattcatata ccatataacc ttcatactca
    41521 ttttgaagta gcgtttgaaa atggcgagta aaatcaattg cgccagatcc tggttggtag
    41581 cgatgattat ctgctaaatg gatatgaccc acatactctt tttgcgtagt caatgctttt
    41641 gaaatatcat cttcttcaat attcatatga taaaaatcag cgatgatctg cacatgtttc
    41701 aattgattag agtcaatgta atgacgcgca tccgctaaca aattgatcat atggtcttgg
    41761 tatcggttca aaggctccaa ataaataacc gtacctgttt cttcggctac tttatctaaa
    41821 taacgaagtg attcgctgac tgctttatag tctccttctt tgcttcgggg tgaaaccatc
    41881 ggcggtaatc gataagtgaa cattccccaa gctgctggga taacgattcc tttgcctcca
    41941 acctcgctta gtgcacgcaa aatctcagca atttgacgta caccattaag acgccgttct
    42001 tcgataaagt caccgatcca cccatcgtag ccgttacaag ctgtcactac tgggatccct
    42061 gtttctttga ttgcctgttt gactgtgtcg atattttcta ttaacaactt accgtcgatt
    42121 tcgtattctt caaatccaca gtctttgata aatctaaatt tttctaaaat gtctcttggg
    42181 aaaaatgctt gatcttgcgt accgaatttc attgttctcc tcctcggact tgaacgccca
    42241 ttttgatact ttcttctggg tgctggtcta cataacgcat gtaagcttct gcgctttctg
    42301 caaatggcac aactggatca atgatttctt cacaatccaa gtaaccgttc atcaataatt
    42361 cccaacatgt gtcctcgatt cgtttacggt tccatcttgg gtaatctggg tttggttcac
    42421 tagatgctcg agcaaagacg atttttgcat tattgaaatg tgcttcgcga ccaagattaa
    42481 acccagctgg aaaaggttta gcaaaggcaa cataagaaat gatcccgcca tagccgatcc
    42541 ctcttaaaga agcttgtaat gcggcagcac tgccactcgt ttcaataact gaatctactc
    42601 cacgtttatc tgtcaattcc tttagacgaa aaccgacatc tgctttcata ggatctagcg
    42661 tgtaatcggc accgtatttt tctgctaatt ctctacgctg cgctatggga tcgatcccaa
    42721 cgatggtagt agcacctgct tttttagcta attgaatcgc aatttgcccg atagcgccta
    42781 aaccgaagat tgctacagca tcacctgctc gaacatgtgc ttcccggata ccacctaaag
    42841 cgaattgagc aggatcgtaa catactgcat ttttccattg atccaaccga tcaagtttac
    42901 gtagtttata attatcaaca ccgtttgtaa tcagcgtttc acgaatgggt ccataagtgc
    42961 agactaactc tcctttttga tactctgtca ccaaactgcc cgtttcttcg atcgtaccga
    43021 caatcatatt tcctaattga aattcgccaa ataccacacc gcgttggctt ccttcttctc
    43081 ttggcaagaa taggcgccat tcttctgaaa attcttcatc gataaatgga cttaatcctc
    43141 taaagtcgac aatttctgtt cctggttttg gagtagcgaa aattactcgg atacgtactt
    43201 cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc ggctattctt ggttctaatg
    43261 caactaattt tttcatcttt t
//
LOCUS       DAKCAA010000017        42995 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000017 DAKCAA010000000
VERSION     DAKCAA010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 42995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.017"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            123..1148
                     /locus_tag="OUE31_001053"
     CDS             123..1148
                     /locus_tag="OUE31_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCU0222076.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            1187..2137
                     /gene="manA"
                     /locus_tag="OUE31_001054"
     CDS             1187..2137
                     /gene="manA"
                     /locus_tag="OUE31_001054"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HCU0222077.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            2231..3934
                     /locus_tag="OUE31_001055"
     CDS             2231..3934
                     /locus_tag="OUE31_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCU0222078.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            3936..5969
                     /locus_tag="OUE31_001056"
     CDS             3936..5969
                     /locus_tag="OUE31_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCU0222079.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDRKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            5980..6420
                     /locus_tag="OUE31_001057"
     CDS             5980..6420
                     /locus_tag="OUE31_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0222080.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(6620..7747)
                     /locus_tag="OUE31_001058"
     CDS             complement(6620..7747)
                     /locus_tag="OUE31_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222081.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(7750..8427)
                     /locus_tag="OUE31_001059"
     CDS             complement(7750..8427)
                     /locus_tag="OUE31_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222082.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            8691..10457
                     /locus_tag="OUE31_001060"
     CDS             8691..10457
                     /locus_tag="OUE31_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HCU0222083.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            10472..10909
                     /locus_tag="OUE31_001061"
     CDS             10472..10909
                     /locus_tag="OUE31_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0222084.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            10922..12073
                     /locus_tag="OUE31_001062"
     CDS             10922..12073
                     /locus_tag="OUE31_001062"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCU0222085.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(12135..12833)
                     /locus_tag="OUE31_001063"
     CDS             complement(12135..12833)
                     /locus_tag="OUE31_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HCU0222086.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNFLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(12826..14178)
                     /locus_tag="OUE31_001064"
     CDS             complement(12826..14178)
                     /locus_tag="OUE31_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HCU0222087.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(14401..15801)
                     /locus_tag="OUE31_001065"
     CDS             complement(14401..15801)
                     /locus_tag="OUE31_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HCU0222088.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            15962..16699
                     /locus_tag="OUE31_001066"
     CDS             15962..16699
                     /locus_tag="OUE31_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HCU0222089.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            16824..17303
                     /locus_tag="OUE31_001067"
     CDS             16824..17303
                     /locus_tag="OUE31_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HCU0222090.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            17300..18067
                     /locus_tag="OUE31_001068"
     CDS             17300..18067
                     /locus_tag="OUE31_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222091.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            18297..18866
                     /gene="lepB"
                     /locus_tag="OUE31_001069"
     CDS             18297..18866
                     /gene="lepB"
                     /locus_tag="OUE31_001069"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCU0222092.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(18970..19572)
                     /locus_tag="OUE31_001070"
     CDS             complement(18970..19572)
                     /locus_tag="OUE31_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCU0222093.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            19678..20147
                     /locus_tag="OUE31_001071"
                     /pseudo
     CDS             19678..20147
                     /locus_tag="OUE31_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            20253..20837
                     /locus_tag="OUE31_001072"
     CDS             20253..20837
                     /locus_tag="OUE31_001072"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HCU0222094.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            20840..21913
                     /gene="prfA"
                     /locus_tag="OUE31_001073"
     CDS             20840..21913
                     /gene="prfA"
                     /locus_tag="OUE31_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HCU0222095.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            21906..22745
                     /gene="prmC"
                     /locus_tag="OUE31_001074"
     CDS             21906..22745
                     /gene="prmC"
                     /locus_tag="OUE31_001074"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCU0222096.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            22738..22917
                     /locus_tag="OUE31_001075"
     CDS             22738..22917
                     /locus_tag="OUE31_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222097.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            22939..23964
                     /locus_tag="OUE31_001076"
     CDS             22939..23964
                     /locus_tag="OUE31_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HCU0222098.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            24139..25383
                     /locus_tag="OUE31_001077"
     CDS             24139..25383
                     /locus_tag="OUE31_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCU0222099.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            25536..26483
                     /locus_tag="OUE31_001078"
     CDS             25536..26483
                     /locus_tag="OUE31_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCU0222100.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISQQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            26617..27246
                     /gene="upp"
                     /locus_tag="OUE31_001079"
     CDS             26617..27246
                     /gene="upp"
                     /locus_tag="OUE31_001079"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HCU0222101.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(27385..27627)
                     /locus_tag="OUE31_001080"
     CDS             complement(27385..27627)
                     /locus_tag="OUE31_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222102.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            27748..27820
                     /locus_tag="OUE31_001081"
     tRNA            27748..27820
                     /locus_tag="OUE31_001081"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27781..27783,aa:Thr,seq:cgt)
     gene            complement(27939..28577)
                     /locus_tag="OUE31_001082"
     CDS             complement(27939..28577)
                     /locus_tag="OUE31_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCU0222103.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(28700..29332)
                     /locus_tag="OUE31_001083"
     CDS             complement(28700..29332)
                     /locus_tag="OUE31_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCU0222104.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            29683..29982
                     /locus_tag="OUE31_001084"
     CDS             29683..29982
                     /locus_tag="OUE31_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCU0222105.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            30477..32642
                     /gene="acm"
                     /locus_tag="OUE31_001085"
     CDS             30477..32642
                     /gene="acm"
                     /locus_tag="OUE31_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HCU0222106.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(32914..33399)
                     /locus_tag="OUE31_001086"
     CDS             complement(32914..33399)
                     /locus_tag="OUE31_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HCU0222107.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    33489..33834
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            33879..34520
                     /locus_tag="OUE31_001087"
     CDS             33879..34520
                     /locus_tag="OUE31_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCU0222108.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            34539..35174
                     /locus_tag="OUE31_001088"
     CDS             34539..35174
                     /locus_tag="OUE31_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCU0222109.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            35192..36007
                     /locus_tag="OUE31_001089"
     CDS             35192..36007
                     /locus_tag="OUE31_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HCU0222110.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            36326..37762
                     /locus_tag="OUE31_001090"
     CDS             36326..37762
                     /locus_tag="OUE31_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCU0222111.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            37951..40398
                     /locus_tag="OUE31_001091"
     CDS             37951..40398
                     /locus_tag="OUE31_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCU0222112.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            40628..41695
                     /gene="rlmN"
                     /locus_tag="OUE31_001092"
     CDS             40628..41695
                     /gene="rlmN"
                     /locus_tag="OUE31_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HCU0222113.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(41888..42991)
                     /locus_tag="OUE31_001093"
     CDS             complement(41888..42991)
                     /locus_tag="OUE31_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCU0222114.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
BASE COUNT        14673 a         7422 c         8785 g        12115 t
ORIGIN      
        1 agtataccgg gggaaactgc gcggtttttc gcgcagtttt tttgtgtaaa aaaggttgat
       61 tcctcataga ttaagcttta agcttggact gtaagaatct gatagaaaag caggagaaaa
      121 agatgtatcc acacacgaaa cagcttattt tgaaaaagat ggaagaagga ttttatccag
      181 gtgtagcagt cgccttcata aaagaaaatc aagtagaaac atttacagcc ggctttgccc
      241 aagtcgttcc tgaaaagcag ctgatgacag aagatctgtt gtttgatgca gcctcactga
      301 cgaaagtcgt tgcaaccact tcattagttt tacgtctatt agaagatgga aagatagaac
      361 tcgatcaacc gcttcataaa tatcttcctg aatttgaaaa tcagacaatc actttgcgtc
      421 atttactgac acatacttct gatatcaaaa catggatacc aaacagagat aagctatctc
      481 aggaagaatt gatcgccgct tatttgaagc tagaaccagg tgagcaacta ggaaaagaag
      541 taaaatatac agatgccggt acgattcttc ttgggttgat gctagaggaa atttaccaag
      601 aaactgcagt ggaaatcttt caagaacaag tattggaacc attaggaatg atgaacagct
      661 tatttcttcc ttttccttcc aaaaaaatcg ttcccacaga acaactgcct tcgggtgagg
      721 ttttgcgtgg acaaactcat gatccgaaag caagagtttt ggctgaacat gcaggtaacg
      781 cgggtctctt tattgatttg aaagacagca ttacttttgt ccaaatgtat ttgaacaagg
      841 gaaaaatccg taatggtcgt tttttagaag aagagacgat tgattcttta ctgcaagatc
      901 aaacaccgaa aaaaaatggc tatcgttctt taggatggga cttaaaaaag gatgtagaag
      961 acggtcatgc gattcttttt catactggtt atacaggtac gtttttcttg attgatataa
     1021 aaacacaaga agcgttgata tttttgtcaa atcgcgtaca tcctgtcgat catcgtgcgg
     1081 agtatctcat atgtcgagat gaaattgttg aaaacttttt gaaagagaaa gcggtattac
     1141 cgaaataatg ctataatagc tatgaaaaat gagaggagtt tgaattatgc aggaacctat
     1201 gtttttaaaa ccagtttttc aagaaaaaat ttggggagga agtcgtttac gttcagtctt
     1261 tggttttgat atccctaacg ataaaatcgg agaagattgg gcgatcagtg cgcatcctca
     1321 tggtgtcagt gtagtagaaa atggcgaatt caaagggaaa agattagatg aactatggtc
     1381 agaacacaag gaattgtttg gccatccttc agaaccagtg tttccattat tgatcaagat
     1441 cttagacgca gaagatgatc tatctgtaca agtacatcca gatgatgcct atgggatgaa
     1501 acatgaaggt gaattaggaa aaactgaatg ctggtatatc atcgatgctg aacctggtgc
     1561 agaaatcatc tatggtcatc atgcaaagac aagagaagaa ctagctgaga tgatcaaaga
     1621 tgggcgctgg gatgaccttt tgaagaaagt accagttaaa aaaggtgatt tcttttatgt
     1681 accaagcgga acgatccatg ctattggtaa aggaatcatg attttagaaa cacagcaaag
     1741 ttctgacacg acttaccgcg tgtatgacta cgacagaaaa gatgcgcaag gacaaacaag
     1801 agagctgcat atccaacaat cgatcgatgt aacaactgtc cctgcgaaaa caccagaatt
     1861 acaaatcaaa gaagtccgaa aagggaattc atcgatcgtc acttatttag aaactgagtt
     1921 tttcaatgta tatgagtggg atattaaagg aatcacatct ttcaaaaaac aagcccctta
     1981 tacattgatg acggtaatcg aaggagcagg agaccttgtc gttgacggaa aaacatatcc
     2041 attagaaaaa ggaacaagct gtattattcc aaatggcgtt tctgagtggg cggtccaagg
     2101 tgaactagca atcattgcgt ctgaaccagg caaatagttc ccagatagct gaaagcagca
     2161 gacggttttt cgtttgctgc tttttctaca taaaatccgt ccatcaataa atagaagtct
     2221 ggtgaaaaag atggaataca aatggaaagc aaacaacagc agtcgcgtgt ctatgaaaca
     2281 actgagaaaa gctggacatc acttaaatga aatgatcatg ccaaatctaa gtctgtttat
     2341 cgcttgggga atcttgtcat tagcaacaaa aggtgtgtct ggcgatttgc acaccacatt
     2401 agaagaggta tgccattgga tgatccagct gcttttaccc atcttgatca gttattcagg
     2461 cgggaaatcg gtagggggac aaaaaggggc agtcgccggt gcaattgctt ctttagggtt
     2521 gatcgctcgt tccaatgctc cacaaatcgt aggagcgatg attatcgggc cgcttgccgg
     2581 catcgtatat gaacaatttg tttctagatt ccatgtgaaa ttcaaggctg gatatgaaat
     2641 gcttgtcagc aacctactag taggactgac tggtagcgtt atttgtataa ttggaatcgt
     2701 ttttattgaa ccagttttaa atagtgttca cttgttgctc gcctccgttg tgtcttggct
     2761 agtcacaatg aatctgttac cacttgtcag tctgatctta gaacctctaa aagtactatt
     2821 tttcaataat gcaatcaatc atggtgtatt gacaccttta ggaatcgaat tctcacaaac
     2881 agtcgggtac tcttccttat ttttgatgga ggcaaatcct ggacctggtt tagggatctt
     2941 actttctatc ctttgttttg cagaaaaaca ggaaaaagta aatgcgagtg gagcattgat
     3001 gatccatgcg attggcggga ttcacgaaat ctattttcca tttgtcttgc tgcgaccgta
     3061 tctattttta gctgtaatgg ctggtggggc aagcggcacg ttgatatttc aatggttaga
     3121 tacgggatta gctgcacctg tatcgcctgg gtcactactc gtgatttttg ccaatgcgcc
     3181 ttatccacaa ctagctgggg taagtatagg gatagcaatc agtacatttg tgaccttcat
     3241 ttgtgcagcg atactattga aattaccaaa taaagaaaaa gagaacaaaa cggtcaaaga
     3301 aaggggagaa atcttggaac catctatcat tcattccgtc atttttgctt gcgactcagg
     3361 tatgggatca agtgctatgg gagccgccct gctgaaaaag aaattagcag cagaaaaaat
     3421 cgatctttct gtcggataca gctctatcta tgaattgaat aaccaagtaa atcagctggt
     3481 tatcgtgcaa catgaactag cgggtcttgc aagagaaaaa gtacctcaaa gtcaaatcta
     3541 tgtactggat cactttttgg aaacagatat cttgctgtca cgaataaaag aagcgatcca
     3601 atttccaaag cgggaagaaa aaaaagagat agcagatatc acagaacaaa aaacgtcgcc
     3661 tgctaatatt gtatttttgt ataaaaacaa cagacgcggc tcacaaacta tgggcatgac
     3721 gattttaagt caattagcaa aaaaagcgaa aaaacagttt gttatctcaa aagaatcaat
     3781 agaaaaaatc aaaatccaag aagaaacgat ttatatcgca caaagagaac tagctgtaac
     3841 tgaacagcta gaagaaaaga tccctcggct agttctagtt gaacattggg tagctacgaa
     3901 tgaatacgaa aaactcgtga agggagaaat ataagatgta tttatcgccc agagaaaaac
     3961 aattattagc agaatttctc agtagcccgt cacctgtatc tatccaaaaa atgatgaatt
     4021 tattgaaggt cagtaaacgg actatttacc gcgaattaga taatcttgaa gtctcattga
     4081 aatcggtaaa tgcttctttg aaaaaagcag ctagaggctc atttgtcatt gaggcatcag
     4141 aagaagtatt agagcaatta aaagaaaata cagataggaa aagtaatgac ttatccactg
     4201 ctaaacgaca acacgcgatt ttagccgagt tgttactgac gacagagccg ttgagtcttg
     4261 ctcatttcat ggaatcatat cgcatcagta ataccacttt ttatgcagat atcaaacagt
     4321 tggaagaaag tattcgccaa ctgcctttgg aaatcattcg gaaccaggga tacgagatcg
     4381 aaggaccgga aaaataccgc cggcttctga cagcgaatgt attagaatta gaaatcaatg
     4441 aatatgaact ttttcatagt atttctttcg atgcatcact gaattatttt tttcgattcg
     4501 ttgatccgca acatctatct cttgcacgca aagtaatcgg ggaagaattg atccaaaaaa
     4561 agaccaatct aagtgataga aagcttgaac atttggtttt gatgctgaca ttgacgatgg
     4621 agcgtgtgac gaaaaatcat ttactgacaa atgagacata taatagtctg gcaaacaaag
     4681 aattactaca gacagctaaa cgattgtttt cacggatcgc ttctgagaca aaacaacttt
     4741 atccagtaaa tgagatcgtc ttttttgcag gattattaaa tgacttcacg aactcatttg
     4801 atcagaattt ctttgaagag acgttcgata cacagcttgc ttatttagta aaacaactga
     4861 ttcaagaagt aagtgaagag acgaatgtcc atttttatga agatgaaact ttgtacaaaa
     4921 tgctgttgac tcatttatct ggtgtgtttt caagagccgt tttacaagaa gagacactga
     4981 ccaatccgat tttagaaaaa atcatggttc aatacgagga agttgcgaat gcaatccgta
     5041 aagcagtaga gcggattttt caagaaaaaa aattatccga agaagagatc gcttatatgg
     5101 tccttcattt tgcgaattca ttggaacgaa gtccgaaaga aagcaatatc agtattgcag
     5161 gattttcgcc aagtggatta gcttctacta gcatgttgga actacgattg aaaaggtatt
     5221 ttcccttcat ccaacaaatt catttctatc ggattgctga tttaaaaaaa atcgatttac
     5281 aagaagaata tgatgttgtt atttctacat ctattttacc aggatacggt ggaaaatata
     5341 ttttagtctc cccgctactg ctagaagatg aagtcaagca gctaaaagaa gctttttcgc
     5401 atattgagaa gaaaaaaagg caaaaaatta cgtataacag caataacgag tggatgatag
     5461 aagatactta tgaggaaaca atgcatttca tggatcaaat caatcaatta ctcggtcgtt
     5521 tttttatcca agaactggat aatcctgaga cgatttccga aacgattcgc agcttatttc
     5581 cttattttcc tgaaggacta gtaacggatg aagaggtggt tcatcgccgg ctgcttaagc
     5641 gatatgaaca agcacctatc ggtattcctc atacaaatat ggggttattc catacatcca
     5701 gctcattgat ttctaaaccg atcttttgta ttttcaattt gaaacatccg ttgaccattg
     5761 aagggatgga tagacagcca gtcgatttgt cccgtatgtt agttatgctg gcgccttcgc
     5821 caatccaaga aaaagacggg attcttttag gaaagatcag tggagcaatc atcatgaatg
     5881 acttgaacac cgagatcttc cgctcaggaa ataaagaaat cgtttatcag ttgttagcga
     5941 aaatcctgat tgaagaaata aagaaatgaa ggtgaaaaga tgatacagct accagcagaa
     6001 aaaatattgc tcgatcaatc ctatcaaaat tggaaagaag cgttgaccga gatcggccag
     6061 tggatgaccc aacaaggggg aatcaaaccg gcatatatcc aatcaatgat cgaaagacaa
     6121 gaaaaagcga gtgtctatat cgggaatttc gtagccttgc cacatgggac tgacaaagat
     6181 gaagaagtag tagaagaagg aatctattta gtccaagtgc ctgatggtgt ggactttgga
     6241 acaaaagagg aaccaaaaat cgcgacactc ttatttgtag tggctttaaa aaaagaacat
     6301 cagttagcgg tgctccaaga tttagccttt ttctgttcag acatcgacca agtaatggcg
     6361 ctcagtgatg cggaaaccat tgaagaagtc caaatgattt ttgaacatgg acatatataa
     6421 ccaatgttca cagtaaaaaa agctgccttg catcaagtaa taacttcaac caagataaaa
     6481 ataagaggag ctatttttgt tgggaggttc ttattactgc ggatgcaagc ttttgaaaac
     6541 tatttattct agaaaaccgt ttatttgaaa taggggacgg tgacaaggtt tttgtcaccg
     6601 cccctattat ttttgtgttt taatagctct tttttatata gatagtgccc atacctatga
     6661 ataataaaac gatactccat ataccaagtg tcaagatacc attcatgaaa gtaacctgtt
     6721 ctgaagctag tggcgagaaa atatctcctc ctatgatcac attttgaaaa tcaacataag
     6781 aagttggcaa gtaatgactg attgattcta tccatccaat cgaagaaaac aagcgatact
     6841 ctgctaagaa aagacaaaga agtgtaccta aaagattgac tagagaatgt tcaaataaag
     6901 cagatagaag aaaactgatt gtacttaaaa agagcaccca caacaacagg aacagaaagc
     6961 tctggaaaag atactcatac atcggcagga ttcgtatctc ctgaccaatg atcgttccta
     7021 caggataacg gaagtctccc aaaccatttt tgattattac tagtatagag acgatcaaaa
     7081 atggcatcac gagacttagc atagctgcac cataataaat ggtaaaacgg atgctatgtt
     7141 tctttaccat actatccggt aatagattga ctagagagat tacctgcttt cttttttcat
     7201 aagagatgat ggaagaaaga aacaaggcgg ttatacataa aatcaaaaaa ctagaaatca
     7261 ttcctgaaaa aatattttcg tagtaatttg ctaaagagag atgcgctggc aagtcaaaaa
     7321 tagaatatct ttggatctga tgttctttca tataacggag caactcgaca cgtttttgtt
     7381 gttcaatgat tggaattcct tgtctttgac cagaaatcag tcgatccagt atatcttttt
     7441 cataatgata agttgcttcg accatttgct ggacattccc tgtgtttttt gcatgtaaga
     7501 ttgcttcgat cagtttgttg cttttctcta aactttccac aaattctttc tcattctcat
     7561 cttctttcaa cgtttcaatc aaacgttgca tctcttcata gttatgattc agttcatcga
     7621 attctgtata agcaagttta tgatcaaaaa aaagtgggaa tgcaaagagc acgaccaaca
     7681 atagaggaaa taaaaagttt actttgtttt ttagtaagag attgcgttca aatgtaagta
     7741 aagacatagt tacacctcat ataatttacg ataaatagct aaaatctctt ccatatttga
     7801 ggattctgtg acgatttctc cattttttag aaaacatgct ttagaacaaa tcgattggat
     7861 attcgcgata gcgtgggaag aaagaagaat cgtcttcccc tctttctgcc attgtctgat
     7921 gaggctattc aagatatcaa tacttcctgg gtctaatccg ttcaacggtt catcgaataa
     7981 catgacagat gaatcactga tcaagtaagc agcaagcaag acatgttgtt tcattcctag
     8041 agacattttt ccaatcggca aagtaaggta ctcagtcatc ttcaatcgtt ggaaaacagt
     8101 ttggcattct actttgctct gccaatagta tttgatcaaa gtcaaataat caacagccga
     8161 tagatagtcg gataactgat tcgttgattc tagaaaaaag aaagaccggc gataatctgt
     8221 ataagcagta ggagagatgt tgtgaaggga caattgatca taagttgttg gcagcagttg
     8281 ggcaatgcca ttcagcaaag ttgttttgcc aaatccgttc ggggcaatca aagcagctac
     8341 ttctcctgat tctactaaaa gattcaattg tcgaatcaca cgttttttac cacgtttcat
     8401 gttcatgttt ttgatcagta atgtcataga taggcctcca atataaaatt taataacata
     8461 atagaatgga aaacatctaa attaaatgct aacaaaagtt attgtttgca tattataaaa
     8521 aaattaaaat aacagtttta tttaaaattg aagttttctg ataccgaaat ctttttattt
     8581 tgctgacata ctcaaacctt tggcacaaag tttcgtgcca aagtacgact atttctcttt
     8641 ttagtaagcg gatacaatta gagtatcaaa aggagagagg gagagacaaa atggaacgga
     8701 cgattcccaa aaacaacatt tcgctaaaag cgagggtaca aaaattaggc agtactttat
     8761 caagcatggt catgccaaat attggagcac tgattgcctg gggtgtatta acggctctat
     8821 ttatcccaga tggttattta ccaaatgagg ctttcgctac catggtaagc ccaatgctaa
     8881 cttatctgat tcctttattg atcggttata ctggcggaaa agtaattgct ggtgaccgcg
     8941 gatcagttgt tggggcaatt gcaacgatgg gtgtgattgt cggaacagat attccaatga
     9001 tgctaggcgc gatgatcatg ggacctcttg gtggatatgc catcaagaaa tttgatcagc
     9061 tattccaaaa acggatcaaa tccggttttg aaatgctagt caataatttt tcagcaggtc
     9121 ttatcggttt tggattagcg ttattaggtt tttctgcgat tggtccagtt gtcgatgcat
     9181 tgactcaagc aatggcaaaa ggtgtagaga tcattttatc tgcccatttg attccattga
     9241 caagtatttt tattgaacca gcaaaaatct tatttttgaa taatgcaatc aatcatggga
     9301 ttttgacacc attgggaact gaacaagtag cagaggctgg aaaatctatt ctattcttgc
     9361 ttgaagcaaa tcctggtcca ggacttggcg tattacttgc ttttactttg tttggcaaag
     9421 gagcagcaaa atcttcagca ccaggagcca tgatcattca ctttttaggc gggatccatg
     9481 aaatctattt tccttacgtt atgatgaaac cgttattatt cttatcagtt ataggcggag
     9541 gaatgtcagg aagtttcatt ttccaattga tggatgctgg actaagagcg ccagcttctc
     9601 cagggtcgat cattgcgatt ctagcgatga caccgttcaa ttcttacctt cctgttattt
     9661 tgggcgtgat tgttgccgca gctgtttcgt ttggtatttc tgcagtaatt ttgaaagcgg
     9721 atgcgaaaga tacaaatgaa gacttcgaaa aatctgttca agagacaaag gcagctaagc
     9781 aagcttccaa aggtgcccaa ggtattcctc aaggagctac attctctggc gtacaaaaaa
     9841 tcatttttgc ttgtgatgca ggaatgggat caagtgcgat gggcgcttcg atcttgagaa
     9901 aaaaagtaca ggaagcagac ttgcctcaaa cggtgaccaa tcaagcaatc agccaactga
     9961 cagatgactc gaatacattg atcgttactc aggtcgaact acaagaaaga gcaaaacaaa
    10021 aagcaccgag cgcgcgtttt gtctcagtag aaaacttttt gaattcacct cgatatgatg
    10081 aaatcattca agaattaagc agcaagcaga aaacatcagt ttctgaaatt gagaatgagc
    10141 cagcagaaga gtttctttca gcaaacatca aacaaatcaa agagattcta cttgtccacg
    10201 atgatcgttc cggatcagca acaatgggga tgaccgtgct caaagatata ttagacaaga
    10261 accatttaac tatcccgtta agaaaagtca atatccaaga tttaaaagat gaacctgatt
    10321 cactgatcgt agccaaagaa agtttagcgg aaaaagtaca gatggctgca cctcaatcca
    10381 ttcatttatc agtcaacagc atggtcaatc cgcaaaaata cgaatcgatt gcacaatatt
    10441 tgaaacagac agcttaaggg aggaaaacag catgcaaagt ttgccattcg acatgatcga
    10501 gctcaatcga tcttttaaaa ccaaagaaga agcgatccgc tattgcggtc agatgcttgt
    10561 agaagcaggg tgcgttgatg aggaatatat cgatgccatg gtagatagag acaaaatgtt
    10621 atctgtttat atggggaatt ttatcgcgat tcctcatgga acagatgaag caaaaaaata
    10681 tgtgaaaaaa tccggcatct gtgtcgttca agtaccagat ggtgtagatt ttggtaccga
    10741 agaagaagaa aagattgcga ctgttttgtt cggtattgca ggagtcggag atgagcattt
    10801 gcaacttgta cagcaaatcg cactttattg cagtgatatg gacaatgttg tccagctagc
    10861 agacgcgctc agcaaagaag aagtaacgga aaatctagca attgcttaag gagagagaaa
    10921 aatgagagca gtacattttg gtgcaggaaa tatcggtcga ggatttattg gagaggtttt
    10981 ggcagctaat ggatttgaga ttactttcgt agatgtgaat cacacgatca ttgatgcttt
    11041 aaatgaaaga aaagaatacg aaatcgaatt agcagatgaa tcaaaagaaa aaatcactgt
    11101 aaaaaatgtc aaaggaatca acaatcaaac aaatccagaa aaagtaatcc aagaaatcgc
    11161 tgaagcagat ttagttacta ccgccattgg cccgaatatc ttacctttta ttgctgagtt
    11221 gattgcaaaa ggtatccaag aaagagaaaa ggaaggaagc acaacatctt tagatatcat
    11281 tgcctgtgaa aatatgattg gcggttcagc atttctagaa aaagaagtgt ataaatatct
    11341 tccggaaaca tcatttactg acaaatatat cggctttcca aatgcagcag tcgatcgaat
    11401 cgtcccatta caacaccatg aagatccttt attcgtccaa gtggaacctt tcaaagaatg
    11461 ggtcattgac gatagccaaa gaaaaaataa aaaaatccaa ttaaaagggg ttttatatgt
    11521 agatgatcta gaaccatata tcgaacgcaa actatttagt gtcaatactg gtcatgcgac
    11581 tgtcgcttat acaggtgcct tgttaggtta ccagaccatt gatgaagcaa tgcaagatgc
    11641 gttagttgtg gcacaattaa aatcagtttt gcaggaaaca ggaagtttgc tgattgccaa
    11701 atgggggttt gatgcagagc agcatcatgc gtatattgaa aaaatcattc atcgcttcca
    11761 aaacaaaaat atctctgatg cgatcacacg tgtcgctcgg acaccattac gtaagttagg
    11821 ttatcaagaa agatttacac gtccagtgag agaactacaa gaacataact tgacttgccc
    11881 acatttgacg gcaacaatgg ggattatttt taattactat gatcctgaag atgaacaaag
    11941 ccgtcaattg catgaaatga agatccatga aaacttggaa caattgattc aagaagtcac
    12001 aggaatcaat gatccgaaaa caatcgggaa tatcaagcaa aacgtgaacc gttatgccaa
    12061 gcaagtcgct taaaatagga tacgaaaaag gggaatgtga cgaaattttt gtcacattcc
    12121 cctttttcga ataactaggc tgtttgtcct tcaagatagg gcagatccaa ttctttaccg
    12181 taacgttgtt ctaaagctag gcggatcaaa cgagctgcca ggttctcatt tcttgcaagg
    12241 ataggtccat ggaaataaga accgaagaca tttcggtaaa tgacaccttc agattggtct
    12301 tcaccattat ttccttgacc ttgtaccact ttccccaaag gtcgttcacc ttcacctaag
    12361 aaagtccgac cattgtggtt ttcaaatcca taataagttt cattgaattc ttcgttatgg
    12421 ataacgatat caccgataaa ccggttattt tcctgactta acgtgtagtg atccagtgca
    12481 ctgattcctt ggatcttttc tccattagct cccatgtagt agtgacctag caattggtag
    12541 ccaccacaaa tggctaacat gacgccatca ttttcgatat agttgatcaa agaatctttc
    12601 tttttctgga tgtcttttga aatgattaat tgctcaaagt cttgaccacc gccaaagaaa
    12661 accaagtcat atttatcagc atcaaaaggt tcatgtatac taacgatctc cgtatggcaa
    12721 gaaaccccca ttttttctgc tatatatttc aacatcaaaa agtttccgtt atcaccatat
    12781 gtgttcatca aatttccata aaggtgggcg atattgagtt cataattagc cacggttcat
    12841 tcctcctttg ataaatcctt gagcagctag ttctttacga agctgcaata cagcagtgta
    12901 agtagctaaa atatagacat gctcagttgg caattctttg attttttcga ttacttctgg
    12961 taattctttt gtttctgtca atttattttc tggaatcccg gcaactttta gacgtaaagt
    13021 catatctgta tgacggtctc ctccagaaat aacagctggg atatccatat cggcaaagtt
    13081 ttcaaaatta ccatcccaaa tccagctgac atcgattccg tctgcgtaat tggcatttaa
    13141 taaagccact aaagaaaatg gataaggagc tagaccaatc atatcgatta cttgattgat
    13201 acctacagga tttttgacaa gtactaatgt acattttttc ccattgatat tgatgacttc
    13261 ttgtcggccg aatactttct cgtcatatcc taaaccttgt ttgattttat caggatcgac
    13321 attgaagtac tctgccactg cagtagctgc taaagcattg tagacattat acataccgcc
    13381 aacttcgatt ccgtattcat gaccatcgat cacgaaatct gctgacacat tgtccatccg
    13441 taccatatca gttaatcgat aatccaattc aggacgtttg aagtcacaat ttggacagta
    13501 atatttccct aagtttgcat aagtgatcat tttataatgc aagatgtgat gacaatttgg
    13561 acataagaca ccgtctgtat tgtaatgagc catttgttca cgatcttctt catggtcaaa
    13621 gccataatat tttctaggat tgactgtttc gatagaattg aagattggtg aatcaccgtt
    13681 actgataatc gttgcatttg gtgactttgc ggcaccgtct acaatcattt tataggtcgt
    13741 atagatttct ccataccgat ccatttgatc acggaaaata tttgtaaata agaacagttc
    13801 tggtttcata tattctgtga ctttgctcaa acttgcttca tctatttcta ggacagcaaa
    13861 ctttttctgt cctttttttg gttttgcctg caagaaagtc gatacaattc cctgtaccat
    13921 attcgcacca gtagggttgg ttagaacttc atcgaattgc tggcgcaaaa tattgactgt
    13981 taaagcggta gtcaatgttt taccgtttgt tccggtgaca acgacgactt ggtagtcttt
    14041 tgccaaacta tctagtatat gtggatcgac tttcagcgct agtttacctg gtaaacttga
    14101 tccgccttta aaaaaagttt ttaatgccca ttgcgacgtt tttccaactg caatcgcaaa
    14161 atgactgcgt attcccatta tgtaacctcc aaaaacgatt tgctgacgaa taaattcaac
    14221 taatcatacc atatgttgaa aaaaaggtta aattgctttt cttattctta agaaaaggtt
    14281 acggctgaaa gtgcatgaaa tcggacaaaa tcgcatgatt taacaaaaaa acagcttgaa
    14341 acaaaatgat tgtttcaagc tgctgtgatt ttattattcc ctcttaccta tattcccatt
    14401 ttaaccgata ataattttct cgcttggata ttcatagcct agatctcgtg tttcttttgg
    14461 cacgaataac atcaatgtat atagcattcc gatccgccca ataaacatca gtgtagcaat
    14521 cgtgattttg cccacaacag acaagtctcc ggtaatccct aaagataaac cagttgttcc
    14581 aaacgcagaa gttacttcga tgatgatcga gatcagcgtt tgttcttctg tagcagataa
    14641 aaaaacgata caaaagaaac acataccaag agaaagcata aagacaacga ctgattttcg
    14701 cacatcatct tgatcgattc tccgtccaaa aatattgatg ttatcttcac ttttgaggaa
    14761 ggaatataga tacaaaccga tgattgctac agtagttgtt cgaatcccgc cgcctacaga
    14821 actaggactg catccgataa acatcagtaa agaaaaaatg atcagtgttg tgatttgaaa
    14881 atcacccaaa tcgtgaatct gcagaccagc attacgagtc gtaatcgaat aaaacatcga
    14941 attgatccat ttgacactca tattggaatc ttggaataaa tggtcctttt ccaatagata
    15001 aatcaagaca gttcccgaaa caaacaagat aacaaaagct aacacagcta atttggtaaa
    15061 caaggaaaaa cgaaacggaa gcttcgcatt ggaacgtttg tataatagcc attcccggca
    15121 ctccatcaat acaggaaaac caattcctcc gacaaaaatc aaaaacatga tcaggatcaa
    15181 gaaaaaatag tcatgtgcaa agggcttgat ggaatcccca gtgacgtcaa acccagagtt
    15241 cgtgacagcc gatatcgcct gataaaaacc gtaaaaaacg gcatcacgcc aacgatcaaa
    15301 atagcctctg taataaaaat aaatagaaaa gaatgtccca aaaagtaatt gaaaccagat
    15361 taaaatagca aaagtgatcc gaatcagtcg gacgatacca gacaaacgcg gttgattcat
    15421 atccgtcatg atcagctgtc gctgtttcag tgtgatccgt cgtttagaaa aaatgacaaa
    15481 agcagtagaa atcatcatga tccccaaacc accaacttga aataatattt ccagcagtat
    15541 aataccgtta tcattgaaca cagaattgat atcaaaagtc gatagtccag tcacactcac
    15601 tgtactgatt gccatgaaca gcatgtccac aaaagaaaca tggctatctg gttcgcgaaa
    15661 aatcggcata taaaatagaa cgagtgataa gaccgtcatc aatatataat aaaaaacgat
    15721 gatttggatc gatgagaaat gattggcagc aaacttctgt cctcgccgct gcagccttcg
    15781 aaagaataaa tcaacatgca cagtactatc ctcctgacaa tagtcgtttc taccagtata
    15841 caaggggaat taggaatact caaagaaatt atcaaacaga taacaataca gctttcgatt
    15901 aaaatagaaa tggcttataa taaggaaaat cctagaaaaa agaaggagga ggaataacaa
    15961 attgattaat gctcaacaaa tcgtagaaaa aatgaaaaat caaaaaataa attatgatac
    16021 agttctgaaa aaaatgatca tgcaatggga gaaagaagaa gtaaagccta agatattaat
    16081 acatacatgc tgtgctcctt gcagtacgca cacattggaa ttcatgtctc aatatgcaga
    16141 gatcacgtta tttttttcaa attcgaatat tcatcctaaa agtgagtatt tgcgaagatt
    16201 acatgaacaa aaacgatttg tagaccaatt taatgagaaa actgaccatc atgttgcgct
    16261 aatcgttgat gaataccgtc caaatgaatt caccaaaatg gttttaacaa accatcttga
    16321 aaacgaaaaa gaaggtggtg ctcgctgcag tgcatgcttc aatatgcgat tagatcttgt
    16381 tgcgcaaaaa gcgcaagaac taggatacga ttactttgga agtgccctga ccatctcgcc
    16441 aaagaaaaat gcagctttga tcaatcagat cggaatggat atccaaaaga tttacgggac
    16501 acaatacttg ccaagtgatt tcaagaaaaa caaaggctat gaacgctctt tgcaaatgtg
    16561 caaagagtat gatatttatc gccaatgtta ttgtggttgc gtgttcgctg ccaagcagca
    16621 aggatgcgat ctgaaagaaa tcaatcggga agcaaaagct tacttaaaaa catcaaccgt
    16681 agtttttgag gaaaattaaa gaaatctttc ggaaaaacgt aagaaaaaaa taaagaattt
    16741 atggtagaaa taaggtagac tgtataattt gtccgtagta aagtaaggaa acaagaataa
    16801 atttcaatga aggaagagat aagatgcgaa aagtagcacc tattttgaag ccaatcgctg
    16861 tattaacaat ctcgacgatt gtcgcgacta ctacaggtat tgtgaatagt tccagctacc
    16921 gtgcaccaag ttcaagttct agtactgtag aagaaacaac accaactact tcagtctcga
    16981 catctgaacc aacaacaacg gaaagtttga atgaaaccac tacgacaagt acatgggacg
    17041 atacaacaac tagttcgtcg tatgatgaga catatacaac tgacagctca agcgaaacaa
    17101 gtaatacggt accagatggc actccatcgg attcaaccaa tccaagtaca agtccggata
    17161 caagtgctag ctccgaaacg ataccaagca gtacgactgt agatgataac acgcaaaatg
    17221 atgatgcagc acgtacagca cagcaaaacc aagattcagg aaatacccaa acgtataacc
    17281 agcaagcagg tgattctcaa tgacattttt actagacctt atcaacgggg tgcataaatt
    17341 ccttggctat ttagacatca gtcctaaata tcttaaccgt ggatatacga ttttaagtgt
    17401 gattcccacg ctttatttat tgagaattgt ttatggactt tggcaaaacc aaaactatct
    17461 tcaatttttc ttatatggac ttgcatttct agtgcttgtt tattttactg ttttaaatgt
    17521 attttattac tttttagata aaaacacgaa agccgatgtc actcagcttt ttgtgaagta
    17581 tttacctgat gaagcgttca acatccagac agaagaatcg atagataatg gaaattcgat
    17641 cgataaagtg aatacacaag aggtcatggt ttcttatgac gaagattatc aattgaaatt
    17701 agccgagaat atgcggtatt tgattggaaa tggtgagatc aaaacaaatg aactcggtcg
    17761 catggatgga tttctggtcg atagaaatac attgtatcct tattactatg tcaagaaaac
    17821 aggagagaaa gagtatgttc taaatattgg acgaagctac tcggacatgg aaaaagtagg
    17881 gaccattcga cttgactcaa cagaagacac attggaacct gtcggattgt tcatcgtcgg
    17941 cggtgatttt gtcaaagacg ggttacgcta tcatgagcct tatcgtctga aattgattgc
    18001 aaaaaaggca cagtcgcagg aagaaccagt ggtttatagt cgtagccaaa gaagaagaca
    18061 ttcataatgt gatgaaacgc cgtgtatcag tggttgcgat aaaaacgttt attcggaata
    18121 agggggatgt gacacgtctt ttgtcacgtt ccttttttat ataacgagaa agataagacg
    18181 aacacatcac ttattctttc ctttcattta taaacattgt agaataaaga aagtacaacg
    18241 aagtattgtg aaaaaacgta ataaataacg aggaaaatac aagtaggagg taagctgtga
    18301 aagaattttt gaaaaattgg gggattttga tccttgtatt agcggctatt ttattagcta
    18361 gagtgtacgt gtttacacca gttactgtaa acgggcattc gatggaccct acattaagtg
    18421 atggacaacg attgatttca tctaagatct caaactatga acgaatggat attattacta
    18481 caaaggaacc gggggatgaa gaacggatga ttgttaaacg gatcatcggt atgcctggag
    18541 atacagtcaa gatggaaaat gaccagttga ccattaatgg caaaaagtat gatgaacctt
    18601 atctggatga gttcaaaaaa gaattttcag aagataagtt acaaggagaa tatgcttata
    18661 gctcaggatt ccaagcacaa gcagaaagtt catccacctt tacgagtgac tttgaatata
    18721 ctgtgccaaa aggaaagtat cttgttctag gcgataaccg cttgatttca aaagacagcc
    18781 gaatgtttgg gttagtcgac aaagatatga tccaaggaaa agttgttttc cgttattggc
    18841 ctctttcaga aattaaaatc atgtgatgaa aaaataaaaa gaagctgtga catgtttttt
    18901 gtcacagctt ctttttccga aaattccttc ttatttcttg gagttgctca ctttttttgc
    18961 aatctcattt taagcttttt ggctgatgga taagaaaagc gaagcgtttt tgttcataaa
    19021 tagcttttcc ccacgatgga aggtatgact agtagcagag acaaagcccg ttttttccaa
    19081 tcgattattc aattcttctt ggctaaagcc attatggact ttcggatgac taatttgttc
    19141 attcttgtca aagtctacga tgatcaattg accgccagga gctaaaattt cataaagttt
    19201 tgtaagaata ttctccgtat caggaatgtg taaaagtaca agtgatagaa ggatgagatt
    19261 agcttggaca gcaggaaatt cgacagaagc atcagcgtgg atcgttcgga catttttcag
    19321 atctgctgct tggatctttt cttctgccat tttcagcata gtttctgaag catcggcaat
    19381 gatcagttct ttgaatcttt ccgcaagcgg taaactaaca agcccagttc cgcctccgta
    19441 atccagcagg actttttggt ggctgtcgcg cggtagataa gtagttagtt cttcgcgaat
    19501 aatcttggct aatgcttgac ggtcagggga atcataatgg ttagcgatgg aatcaaaaat
    19561 attttttgtc atcaaatagc tccttacgta aaactttgaa attttaactt attatagcac
    19621 gtgaaaagaa agaaagcatg ctatactcaa ttcaaaaagg gagaatctag aaagaatatg
    19681 ccgatatcgt ttgtaaaaga tagagaggaa aaaggaaagt gtgtccgaga aatattacta
    19741 gacttgcctg agtggtttgg gcttcctgaa tcaacggaaa aatatatcga ggaatcaagt
    19801 aaactacctt tatggtgtga aaaaagaaaa gaagaatatt taggctttat cactctttca
    19861 cagacaagtg aagatactgc cgaaatctat tctattgtat gggaataaaa aaagactatc
    19921 atcaccaagg attaggaaca aaacttttta aagaagcaga aggttacgca gcaaaacatt
    19981 acaaatattt gcaagtgaag actgtagacg aggggcacta ctctatatat gatcaaacta
    20041 tttgtttcta cgaatcatta ggattttcaa ggttggaagt ttttccaaat ttatgggatg
    20101 aatggaaccc atgtttagtt cttgtcaaaa aattggaaca aaagtgagca atagatttaa
    20161 tactaatctg tgcttgatga aaattctcac tgtaaaaaat gctgaaaatc aagtataata
    20221 ccataggaac aaactggaag gtgaaaaaga gcatggcaca actatttttt aagtatggcg
    20281 caatgaatag cggcaagacg atcgagatcc taaaagtcgc acataattat gaagaacaaa
    20341 ataagccagt tgtcttaatg acaagcggta ttgatacaag agatggttta ggcgttgttt
    20401 caagccgaat cggactgaaa cgtaatgcga tgccgatatt tgaagaaaca gacgtatttg
    20461 acgtaattca gaaaatggaa agcaaaccct attgtgtgct gatcgatgaa gcgcaattct
    20521 taaaaaagaa acatgtcatt gcttttacga gaattgtgga cgaattggat attccggtta
    20581 tggcatttgg tttgaaaaat gattttcgaa acgagttatt tgaaggatca aaatatttat
    20641 tgctttatgc agacaaaatc gaagaaatga aaacaatctg ttggttctgc cacaaaaaag
    20701 caatcatgaa tttacattat attgatggaa accctgttta tgaaggcgat caagtgcaaa
    20761 ttggcggaaa tgaagcttat taccccgttt gtcgaaaaca ttactttcac ccatcaatga
    20821 ttacagaagg agaataagca tgtacgatca attacaagca attgaagacc gttatgaaga
    20881 gcttggagaa cttttaagtg acccagaagt gatttctgat acaaagcgtt ttatgcagct
    20941 ttcaaaagaa gaagcaaaca cgcgcgaaac agtcgaagtt tatcgtcgtt ataaagaagt
    21001 agtacaagga atcaccgata cagaagaact gcttggtgaa aaactggatg atgaaatggc
    21061 tgaactagca aaagaagaat tatctgaatt aaaaaaagaa aaagaagtct tagaagaaaa
    21121 aatcaagatc ttgcttttac caaaagatcc aaatgacgat aaaaatatca tcatggaaat
    21181 ccgtggagca gcaggcggag acgaagcagc attattcgct ggcgatcttt tcaatatgta
    21241 ccaaaagtat gctgaagcac aaggctggaa aacagaagtg atggaagcta acgttaccgg
    21301 aatcggtgga tataaagaag tgatcatgat gatcaccgga gacaacgtat attcgaaatt
    21361 aaaatatgaa agtggtgcgc accgcgtcca gcgtgttcct tcaactgaat cgcaagggcg
    21421 tatccatact tccaccgcaa cagttgtcgt gatgccagaa gctgaagaag tagagatcga
    21481 tattgaagac aaagatatcc gtacagatat ctatcatgct tcaggtgctg gcggacagca
    21541 cgtcaataaa acagcatctg ctgtacgttt gactcactta ccaacaggga tcgttgttgc
    21601 tatgcaagat gaacgttctc aaatcaagaa ccgtgaaaaa gcaatgaaaa tcttgcgtgc
    21661 tcgtgtgtac gataagatcc agcaagaagc acaaagcgag tatgatgcca atcgaaaatc
    21721 agcagtcgga actggggatc gttcagaacg gatccggacg tataatttcc cgcaaaatcg
    21781 tgtgactgat catcgtatcg gattaactat ccaaaaatta gatcagattt tagcagggaa
    21841 attagatgag atcgttgatg cattgatcat gtatgatcaa acatcaaaac tggaagctat
    21901 gcaaaatggg taaaatgacc tatcgagaag tcctgtcacg ggcttcttct tttttagagg
    21961 atcatgggaa agaagcatat agtatccaat ttttattttt ggaacgaaaa caatggaaaa
    22021 aacttgattg gctccttcat atgaacgaag agatttcaga agaagaacag cggttgatcg
    22081 aaaccgatct gcgacttctg cttgcagatc atccacctca gtatttgcta ggatatgcag
    22141 atttttatga tcatcggtta aaggtaactg aagcaacact gatccctcga ccagaaacag
    22201 aggagttagt cgaatggtgt ttagacgaga cgcctggtgt accgttagaa gtgatagata
    22261 ttgggacagg gactggagca attgctatta gtttgaaagc agcaagaaaa aattggcata
    22321 tatctgctgt ggatctttca gaagaagcat tagaagtagc gaaagaaaat gctcagaaag
    22381 aaggaacgaa aatcagtttt tatcatggag atacattagg accagtaatg gatcagcaat
    22441 ttgatgtgat tatttctaat ccgccgtaca tcagtcggaa tgaatgggaa ctgatggatg
    22501 aaagtgtccg gtcattcgaa cctaaaatgg ccctttttgc tgagaacgat ggattagcta
    22561 tttatgaaaa aatagcagtt gaagcaccaa gcgtactaaa atcaaatgga aagatttttt
    22621 tagaaatcgg atttcgccaa ggtgaagcag taaaaaaaat atttcagcaa gcatttccag
    22681 ataaaaaagt ggcgataaaa aaggatcttt ttggcaatga acgaatgatc caagtttatg
    22741 gttgaagttg tggatgaaaa attttttatt tgttttttta ttataaaaaa acacttattt
    22801 gacaaggatg taaacgactt tttggtttat caacaagttt atccactatt gacaaataga
    22861 ttatccacaa acagtggaaa acttgaggat aaactcagac aaaataagaa tgtatgaaaa
    22921 aggggttgtg gataaactgt ggaaacgaaa cgatatgatg aaacagaatt gcaagaggca
    22981 gccgaagcac tgaaagaagg agaacttgtt gcttttccta ccgaaacagt atacggattg
    23041 ggcgccaacg ctcttttacc aaacgctgtc aagaaagtgt tttctgtaaa agggagaccg
    23101 caagataatc cattaatcgt ccatgtcgcc tcttttgaac aagtaaaaga gtatgtggac
    23161 aactttcatc cggcagcaga gaagattgtg aagaacttct ggcctggacc attaactttg
    23221 atatttaaga tcaaaaaaga cactttgccc tcagttgtga cgggaggatt atccacagct
    23281 gcatttcgta taccggataa caaaaaaaca ctagaagtaa tcgaactttc cggtgttccg
    23341 cttgtcggtc caagtgcaaa tacgtcggga aaaccaagtc caacgactgc agatcatgta
    23401 tatcatgatc tacaaggaaa aattaccggg attattgatg atggagctac gcgaattggt
    23461 gtagaatcca ctgttcttga tttaagtgat ccaacagcca tgcctatgat tttacgacca
    23521 ggtgcagtaa cgaaagaaca aatcgaagca gtcatcgaat ctcctgttgc tattgatcag
    23581 catcttgtaa aagaaaatga aacaccaaaa gcccctggga tgaaatacaa acactactca
    23641 cccgatacac gtgttctgat ggtcagagat ggcgattggt caactgcagt tcaatgggca
    23701 aaaaataaga agatccgtgc aggtgtcata gcaagccccg aaattgcgga tcaagtgcgg
    23761 acagatactg cagctgttta tatgtataac gacaactcag tagaagcggc ggctaaagga
    23821 ttgtttgcag gtctaagagg attagatgaa ccaacacttg gattagattt gatttttgta
    23881 caagtgtatc cagaaactgg attggggaat gcttacatga atcgcttgaa aaaagcagca
    23941 ggacaaaatt attttgaaaa atgatcaatt ggttattgtc gcattctttt agtatgatac
    24001 aatgctatca agtaaatctt ctatcagtga acgaaaaact aagcgtaact aatcgtaata
    24061 gaagagatac gaatatttgg caatttgttt ttgatgggaa aaataaaatt gtaggaaaat
    24121 aaaaaggagc tgttgtttgt ggtagattac aaaacgtttg accctgatct ttgggctgcg
    24181 atcgccaaag aagaagaaag acaagaacat aatttggagc tgattgcctc tgaaaacttt
    24241 gtctccgaag cagtgatggc tgcacaagga agtatcttga caaataaata cgcagaaggt
    24301 tatccagggc atcgctatta tggtgggtgt gaatttgtcg atatcgttga aaatttagcg
    24361 attgaccgtg caaaagaatt attcggagcg aaatttgcga acgtccagcc tcactccggc
    24421 tctcaagcca acacggctgc ttatctcgct ttggtagaac caggggacac gatcttagga
    24481 atggatcttt ccgcaggcgg acatctaaca catggatcac cagtcaactt cagtggcaaa
    24541 acctatcact ttgttgctta cggtgttgat ccgacaacag aagttattga ttataatgtg
    24601 gtacgtattt tagctagaaa acatcaacca aaattgatcg tagcaggtgc cagtgcttac
    24661 ggacgaacga tcgactttgc gaaattcaga gaaatcgcag atgaagtagg cgcaaaactg
    24721 atggtagata tggcacatat cgcaggatta gtagcagcag gacttcatcc taatccagtt
    24781 ccttatgcag atatcacaac gactaccact cataaaacat tgcgtggccc tcgaggcggc
    24841 atgattttga caaacgatga agcattagca aaaaaaataa atagtgcggt atttcctggt
    24901 attcaaggcg gccctctaga gcatgtgatt gcgggtaaag cagtagcatt caaagaagca
    24961 ttagatcctg catttaaaga atatagtgaa caaatcatcg ccaatgcaaa agcaatggtc
    25021 aaagttttca atcaagcaat tggaaccaga gtcatttcag gggcgacaga taatcatctg
    25081 atgttgatcg atgttcgcga gttaggtata aatggaaaag aagcagagag cattttggac
    25141 agtgtgaata tcactgtaaa taaaaactcg attccttttg aaacactaag tccattcaaa
    25201 acaagcggta ttcgaatcgg cacgccagca atcactactc gcgggttcaa agaagaagat
    25261 gctgtaaaag tggctgaact agttgtcaaa gcattacaag caaaagatga taacgctcaa
    25321 ctagacgaag tcaaaacagg tgtacgcgaa ttaactgaaa aatttccgtt gcataaaaaa
    25381 taaaaattta aattccatta gtaaacagaa aagttcaatg ttgggctttt ctgtttattt
    25441 tttgggaaaa cggattcttt gacaatatcg gtgatgctct ctagtatatg aggtgtaatt
    25501 ttagtcttca cactaaatct cagggaggaa aagtcatgac tgatcgtatc tcgttagaaa
    25561 aggaagcagt agcattcagt gatgcaaatg cgcctcatcc gcgtatctat gaactagcac
    25621 cggaagaagg aagagtttta ctagaagaag tacaagaatc acctgtgaac aaatattccg
    25681 tcgatattga agacttgatg gtggatactg gcgaatgggg aaaactcaat attcgtctcg
    25741 tacgaccaga agggaatatg gataaattac cagttatttt ttatattcat ggagcaggct
    25801 gggtttttgg cagtgctcaa acccatgata aattgatcag agaacttgcg gttcgtacga
    25861 attccgtcgt tgtctttcca gaatatagtc gatcaccaga agcaaaatat ccaacagcaa
    25921 ttgaacaaaa ttatgctgtg ttgcaacagc tgaataaatt agccaagtca aaaaatctgg
    25981 atctcgagaa tctaatcgtt gcaggagatt cagtaggtgg taacatggct acagtcatga
    26041 cgatcttaac aaaagaacga aagggcctcc caatatccca gcaattgctg tattatccag
    26101 tcacaaacgc tgattttgat acagattcct atcatgaatt cggagaaaac tattttttga
    26161 caagagaagg aatgatgtgg ttttgggacc aatatacgac gaatgaagaa gagcgtgctg
    26221 aaatcacagc ttcgcctttg agagcaaata taaatgaact aaatgatctt ccttcagcaa
    26281 tgattttaac gggagaagcg gatgtattaa gagatgaagg tgaggcttat gcgcgcaaac
    26341 ttcgtgatgc aggggttcct gttacacaag tacgcttcca aggaatcatc catgattttg
    26401 tcatggtaaa tgctatggat cagacaaagg caacgcgtgc agcaatggca ttatctactt
    26461 cttggatcaa gaaaaaagaa taagctttgc ttgtccgcag gaaaacttct tttcaaaaac
    26521 ggattttctt aggaaaaatg gcgagtttga ctagtcaatc acttgatttt gttttacaat
    26581 taaaaagaaa cgacagaaca aaggagagct taaaaaatgg gcaaatttca agtgatcgat
    26641 catccattga ttcaacacaa actaactatt attcgggaca aaaactgcgg aacaaaggtt
    26701 tttcgtgaag tagtcgatga aatcgctatg ttgatggcat atgaagtatc acgggatatg
    26761 ccattggaag acatcgtgat cgaaacaccg atcactgaaa caacacaaaa aacgttgtct
    26821 ggtaaaaaag tagcgattat tccaatcttg cgcgcaggta ttggaatggt tgacggtatc
    26881 ttggaattga ttccagctgc taaagtggga catatcggtc tttatcgaga tgaagaaaca
    26941 ttggaaccac atgaatattt cgtcaaactt ccagaagaca ttgatgcacg tcagttgttt
    27001 gtagtagatc caatgttggc aacaggcgga tcagcaatca tggcaatcga tgcattgaaa
    27061 gaacgtggcg cgtcgaacat taaatttgtt tgtttggtag cagcacctga gggagtaaaa
    27121 gctttgcaag aagcgcatcc tgatattgac atctatacag cttctctaga tgaaaaattg
    27181 aatgaacatg gttatatcgt tcctggacta ggggatgcgg gtgaccgttt gtttggtaca
    27241 aaataagtaa atacgaaaaa gggtgtgaca caacttttgt cacatccttt tttggtcatt
    27301 tttaacgttt gatgcagaac agctttttca cagctttcgt ttgcatataa aaaaaccatc
    27361 ccaaaaatgc agagatggtc aaattcaaat cttttttagt tctttgtagt taacgattac
    27421 tacaccctta ctttgcgtca tcaagttcgc attttctgca gtttcatcaa tctcaacaac
    27481 agcggaattt ttcaattgct ttgaaatcgt tccagtttgc gacttgccgt gaattgtgaa
    27541 cattacgtga gtattgatct tgaatttttc accaatttcc gatggtacga tagttgtatc
    27601 aaattttcca aaagttgcca ttttcataaa acctgccttt cacatcaatt ataccacgtt
    27661 ttatgaaaaa tatcatgaaa ttaaactaat tttccatcgg actctttaca atcagccaaa
    27721 tagagtatat aatttctttt ggataaggcc agcttagctc agttggtaga gcaacgcact
    27781 cgtaacgcgt aggtcgtagg ttcgatccct atagctggca ttaaaagaga agacagatat
    27841 atcaaggatt tttaatccat tgatacatct gtctttttgt ttaaaggaaa taaagtatgc
    27901 tttcttagca atagagcatg tattatttct ataaaaattt aggagaataa aacgactagc
    27961 aatatagctg tgaaatcaaa tatcacatga actgcccaac ttgtaatgat cgagttgctt
    28021 ttaatggcag cttggttgaa taacaatctt gccacccctt gtatcaaaag gatgtgtgct
    28081 acagtgtgta aaatatttcc attatcataa gtactgtaat ggataaatcc aaagatgatt
    28141 gctgacaaga aactagcgac aggaatgctg aacttactag aaaaaatagc gagaaaatac
    28201 actgagaaca attcttctcc aagtatcatg ataggcaaaa taataaataa taacgggctg
    28261 aaagcctcat ttattggatt gcctgttaaa ccccatttca aaatttgttg caaaaatacc
    28321 gagactgcgg cactgattac tacattgata aaaaaatatt tggctatatt tttgacagga
    28381 gcgacaggtt tcgagaacat ttttttcgta tcttttttac caaaaacaag tgtaaatgct
    28441 ataaatccag tgatagttaa agaaaaaatg ctaataatgg atggcgcaaa tagcaaccct
    28501 aacaaaccga gtacaacgac aatagtgccc aatatccctt ttttaagttc tatttttttt
    28561 cctaaaatgt tattcatgat aataactcct actattcagt ttttgaagat agagtcagta
    28621 tacatgaaga gttaaaatag gcaatgtttt tttatggata tttgtattgc taaaaattta
    28681 tcttatatat tcattttgat tatactactt ttatttgtaa aaattttcta gcaaaaccaa
    28741 gtgcttgcaa ctgattaagc gtacaatttt ttagatgttc cgagcgtact tcaatcattt
    28801 caaaggagtt gctacttaaa tcgatatttt ttaaatcagt atcaaaaaag ctagcatttt
    28861 ctaaatcatt agtagaaaac attattttag tgagggaaca gtctacaaaa tctgcgcttg
    28921 ataagacaga gtgctcaaag gtactttctt ttatgtttga accagataaa tttacatagt
    28981 ccattttaca attctcgaat aacgtgttcc caatataact ttccatcaat ttagtacctg
    29041 ttaatttaca attgacaaat ttcacgcgat gcaacatgct ttttgtcaat atacagcctg
    29101 aaaaatcaca gttttcgaat atacagtcgg taatctccat tctttgaaaa tcattggaag
    29161 caaaaaatgc atacttgaaa atagatttgt aaataattgg atggcagatt atttggtttt
    29221 cgatgacctc tttttgtgaa aggatattat acagttcaaa atcttcgttt tcatagatat
    29281 gaaaaaagga tcctttattc aagcttgctt cattaacttt aggaaaaatc atatttaatt
    29341 acctccattt tcataaagtc atattaacaa aagctaaacc aacttacatt agcagaaaat
    29401 gagataggtt ttcgcctttt tcgataacga tagtgtcgct atctcttgaa acgttcttag
    29461 aattgccctg agagacacaa attaggcgta attctaataa aaatcttaga ataaaaattt
    29521 ttactgattt aatttagaat gtttttaaaa taaaaatcgt tgccataaca gtgtattgaa
    29581 aggttttaac aatccagtaa tgatttaaaa aaatctagat gtagcgtata ctttgtttat
    29641 agaatgtagt gggaagaaat atatttttgg gaggaaatcg tgatgtctaa aagtgaagaa
    29701 atagaaaaca tggtactaaa attatatgat ctcgttttaa atccagagat caaagaaaag
    29761 gaacgtatac ttttgataga cgcaaagaca ggcttagaaa aaggtcagta ttatcctaaa
    29821 gtcataaata atttggaacg tagtttacgt ccgttagcaa tcaggggaga attgtctaaa
    29881 ccagtatcac cgttttatat ggagatatca acaataggaa aatttgaaaa agaattaggt
    29941 cgaggaatgg cttcggcacc gattactttt gggcatttat aaaaacgagt tattcatctc
    30001 aatgaattaa aaagtatagt caatctcata atgcaggcta ggttcattta tttgaacaga
    30061 gtctgtattt ttttattcta aataaagaaa cagatgtttc tttatattgt attttatcct
    30121 ttaattaaca caaaaacagc tagtataaac taataatgtt aattaaaagt gtattttatg
    30181 aaactatcgt tatttattaa tgttgcattt ttgtaagtta aaaattggaa atatagattg
    30241 aaaaaatgaa agcaataagt aaaataaaat gaatatatgc gaaaaaataa tttacattag
    30301 gaaaaacctt gtaaaaacag ttttttggca tatttatttt ttataaatat ttgtaaaata
    30361 actatcaatt ttttagttaa aagattggaa atgagtgggg gaggaattga agaaaggatt
    30421 tttgagagat gatatagtag gttttatttt tagttaaaat aggggagata gaaaaaatga
    30481 aaaagtgtag aaatattatt ttatcaatgt tatttattat tactaatata acatcactga
    30541 ttcctgttca tgtctatgcg gatgcaggca gagatatcag cagtaatgtc acttcgttga
    30601 ccgtggaccc aacgaatatt acagatggag gaaacataaa agtaaaattc tcgtttgacg
    30661 aaaaaaaaca aaatatccaa ccaggtgatt atctttggat caattggcca agtgaaggaa
    30721 atattcgcgg tgaaggattc caaaaagaaa tcccattaat gattgaaaat aaaaatgttg
    30781 gaactttaac ggtcagaaaa gattctgcgc aggttgtgtt taatgaaaat attaaaaacc
    30841 tagactcagt agaaggttgg gggcaatttg agatacaggc cagaaacgta accgataccg
    30901 gtgaagaaaa tacgggacca ttcaccgtga cgagcggtga taaaacagct actgtaaatg
    30961 tgacaaagcc agcttctggt tcttcttcta gcgtttttta ttataaaaca ggagacatgc
    31021 tacctgaaga tactaagcac attcgatggt ttttgaatat taacaataac ggcacttatg
    31081 ttgaacaacc agttaaaatc agtgatgaaa tccaaagtgg acaaagatta gatccaagta
    31141 cgtttgaaat taatcaaata cacttaggtg aacagaaggt ttatagagga gaagagggaa
    31201 tccaacaatt tttacaagat ttccccagcg ctacatttaa tttttcagta actgataatt
    31261 acattgaaat aactatacca aaaaactttg tcaatcttag gaaaataatg gtgagttata
    31321 agacgatcat agaaaaccca gaacaaataa attttgagaa tcattcggaa gcttggttta
    31381 aagaatttaa taaacctgct gttgatggag aaagtttcaa tcatacagtt aaaaatattt
    31441 cagcttctgg tggagtcaac ggtacagtta gaggcgaatt gaagattttc aaatatatca
    31501 atgacacaga gattggtatc ccaaatgtga ctttcgaatt aagacgagca gatgaacagc
    31561 ctattcaagg acagtctagt atcctgttga cttcgaatga acagggagaa gctagtatca
    31621 aaggcctgca agtaggagac tatgttgtaa aagaaaaaga agcacccaat tggattgatt
    31681 ttgatccact aagttcaaat gaactcaaat tctccataaa cgaaaatgat acagagggag
    31741 tcagtttacc tatttataac aagaaaaagg ttacgaacat cacagcaact aaaatttgga
    31801 acggtggaac cactccaaga ccgagtattt attttaaatt attcagagca agtacaaaca
    31861 attgggaacc agttcctgat gcagaaacaa aacgattaga caatggaata acttcagtga
    31921 cttgggaaga tatccaacag tatgatgata gtggaaacga atatacgttt aaagtgcaag
    31981 aagtagatca aaacggaaat gattatgtcc cttcaggtta tcaaaaaatt gaaaacgggc
    32041 tagtcgttac aaatgagaat aaagaagtca tttcagtctc aggacaaaaa acatgggaag
    32101 acaatgagaa ccaagacggc aaacgaccga cgacgatcac agtaaatcta ttagccgacg
    32161 gtcaaccgat ccaacacaaa gaagtaagtg aaaaagatga ttggcgctat cgtttcacaa
    32221 atctgccaaa atacagagac gggcaagaaa tcatctatac tgtaacggaa gacaacgtgc
    32281 ccgaatacag tacgacgatt gacgggtata acatcaaaaa cagttataca ccggaaaaaa
    32341 caaatatatc tataccaggt agccatataa caccgtggaa aaattttcca gagaagacag
    32401 agagagagaa aattagaaat ctattctctc aaaaattgca aatatttgct catacaggag
    32461 aatccagcga acaaagaagc aattatatta gtaagagagc tgtacctaaa cagataacaa
    32521 ataaatcaaa aagcattctt cctaaaacaa gtagtaaaaa atctagtttt gctgtaatca
    32581 ttggtttatt gatagtaact atctgtgctg ggatattctt acaaaaatat aaaaaagttt
    32641 agttagaata taatattttt tgttaaatat gactgaaatc aaaagaataa aattccgatt
    32701 tataatcgaa aaaagaagca tttttatata tgcttctttt ttcgtagaat caataaatat
    32761 ggatttggct aactatggaa gaatactcgt attagttttc agcgttcata ctagttgtta
    32821 cattgtttga ttggccaaaa gaatttctga tatattttgt gctaaataaa gaaaaagacg
    32881 cttgaattgg gaaataagaa aactactcta tcattacaaa ttttcataaa ctggcagatg
    32941 ttctaagtaa acaagtatct tttcaaagtc ggaaaaatcc ataatcaacg tagtggtatt
    33001 gatatttgga tgaaagccta cggtatcttg acgatcaata gcagcatcga tcacgacttg
    33061 gatttttttc tctttgtcgt gcatcaatgc taatggagtc actgtacctg ctggaacgcc
    33121 taggaggtca ggaagctgtt cttcagaaac aaaagataag cgcttttctt ttaattgttc
    33181 agctagttgt tttaaatcgg cgtgcttttc atcaggcaag atgacaagat agatttgttt
    33241 tccttttctt gatttcaata atagattttt tacttgcgga ccaggtaggg aaaaagggac
    33301 atttttgact gacgtaatcg caggatgatc gactttttga aaagagatac ccagtttttt
    33361 tagtagttca taagcttctt gttcggttgc acgactcatc gcgcatcacc ctcctttttt
    33421 tattagtgta tcataaaaaa gagttgacaa atgaaaaata atcatgtaaa ttacacgtaa
    33481 agttaaaaca aatgacatcg aaaagaagag tagccgttag gtgtttttag agagtctctg
    33541 gttggtggaa agaggcagca gttaaccgtg aaacacatct tggagtcgat tttctgaagc
    33601 gtatagtagg aaaatccggg gagcccgtta cagctgcggt cgttgctaga tgaccagata
    33661 aggctggctt ttccgtgagg agtcggtaaa aaaaggtgga accacgtgat taacgtcctt
    33721 tgatcttcgg atcaaaggac tttttgtttt catctgaacg gcaacgactg tgtgaggttt
    33781 tttctgcaag gaaaaaataa acagaggtgg aaccacgtat aatacgtcct cttggcattt
    33841 gccaagagga tttttttatt ttaaaggagg aaaagaagat ggagtatttg attgaagtta
    33901 tgccgcaatt attagtagga gcactcacaa cattgaaatt atttttattt accttgattg
    33961 gctcattacc attagggatt gttttagcat taggattgtc tttgcatttt aagccgctac
    34021 gctacttgct tcaaacatat gtatgggtta tgcggggaac accgctgttg ttgcaactga
    34081 tttttatttt ttatgggttg ccgacgattg ggatcgtttt tgatcgtttc gaagcagcac
    34141 tcattgcctt tatcttaaac tatgcagctt attttgcaga gatctttcgt ggagggatac
    34201 aatcgattcc tcaaggtcaa tatgaagcag cgcaagtttt gcaattaagt ccctttcaaa
    34261 cggtgacgaa aatcgtcatc ccacaagtga caaagattgt tttaccttct gtagggaatg
    34321 aagttatcaa cttggtcaaa gattcttcct tgatctatat attaggttta ggtgacgtaa
    34381 tgcgtgctgg gaaaatcgcg atggaacgcg acgcgacttt actgcctttg ctaggcgtgg
    34441 caatcatcta tcttacattg actggtattc taacaatcgt aatgaaacaa gttgaaggaa
    34501 aattaaatta ttaccgctaa ctgataggag gaagaaatat gattgaattg aagaaagtga
    34561 acaaagcatt tggtgaaaaa aaaataatca aagatttgaa tctaatcatt ccagatggga
    34621 aaacattagc tatcgtaggt ccttccggtg gcggtaaaac cacgctttta cgtatcttgg
    34681 ctggcttaga aagttctgac agcggagaat tttatttaga cggtgtaccg ttcaacccat
    34741 tcgagcttaa aatgaaagaa caagttgtag gagtcgtatt ccaagacttc cagctatttc
    34801 cacatctgaa tatttttgaa aacattacct tagcaccaaa aatggtattg aaacagacaa
    34861 aagaagaata caccaaaaaa gcagaagaat tagcggcttc attagggatt agtgatttat
    34921 tgaatatcta tccttatcag ctttctggcg gacaaaaaca gcgggtagcg attgccagag
    34981 cattggctat gaatccacgg gtattggctt atgatgaacc aacaagtgct ttagatcctg
    35041 aattacgcca gcaagtcgag cgtttgatcc tatcattgaa agaagatggg gtaacccaaa
    35101 ttattgtcac ccatgattta gtatttgcag aaaatgtcgg tgatcaatta ctaaaagttt
    35161 ccccaattca ttaagaaagg agaagataga gatgaaaaaa accagttttc tattcgcttt
    35221 gatcgcaggt cttcttcttt ttgcaggctg ttcgaacaaa aaaacttcag cagataattg
    35281 ggcgactatc aacgaagaga aaaaaatcgt tataggttta gacgatacat ttgttcctat
    35341 gggatttaga gataaagacg ggaagctcac aggatttgat attgatttag ccaaagcagt
    35401 ctttgaacaa tatgggatta cggtagactt tcagcccatt gactggtcaa tgaaggaatt
    35461 tgaactgaac aatggaacga tcgatttgat atggaacggc tattccaaaa cgccggcaag
    35521 agaaaagaaa gtgcaattta caaaacctta tatggaaaac gatcaagtgc tgatcacacc
    35581 taaagaatca ggaatcacaa actttggaca aatgaataat aagagattag gtgcgcaaaa
    35641 tgggtcatct ggttatgatg tatttacgaa acaaccagaa gtattaaaag agatagtcaa
    35701 aaaccaagat gctgttttgt atgatagttt taatgaagca ttgatcgatc tgaaaagcag
    35761 acgggtcgat ggtctgctga tggataaagt atacgcagac tattatttga aacaaagaaa
    35821 cgaactagaa gacttcaaca taacaaaagg ttcttatgag agtgaggatt ttgcagttgg
    35881 tgcacgcaag tcagatagta cattagtgaa aaaaatcaat gaagccctag atcaactaga
    35941 gaaaacaggt gaattccaaa aaatatccga taaatggttt ggcgaagatg ttacgccgag
    36001 aaattaacaa ataggggact gtgacaaaag acgtgtcaca gtcccttttt ccgaataaac
    36061 agtgttctcc tgccaactcc ttgtgactcg gagctgaatg gcaggctcac aacctcttgg
    36121 taaacggtgt tcaaaagcca gtttttcggt attaagccaa atttatgcaa aaatgtagaa
    36181 agccattttc acaaaatttt tcttactact cgaaactaag cgactttttc acaacctcct
    36241 ttacatattt ttattttgtt gtggaagggg tttcgtgtta ttctaaaaga ggaacgattg
    36301 aaggttatag gaaaggaaga gatgaatgga acacaaagaa cttacctcat ttccaaaaga
    36361 ttttctgtgg ggctctgctt ctgcagcgta tcaagtagaa ggagcttggc aagaagatgg
    36421 gaaaggagaa tcagtctggg atcgatttgt acggatacct ggaaagacat ttaaaggaac
    36481 gaacggtgat ttggcagtag accactatca tcgttataaa gaagatattg ctttaatgaa
    36541 agaacaaggt ctgaaagctt accgcttctc tgtagcttgg acacggattt ttcctaatgg
    36601 acgaggagaa gtcaatcaag ctgggctcgc tttttatgag agattgatcg acgaattgat
    36661 tgaaaacgat attgaaccta tgttgacttt atatcattgg gatcttccac aagcattgca
    36721 agatgaatat aatggttggg aatcacgtca gatcattgaa gatttcactc attatgcaga
    36781 aacattattt gaggcattcc gcgggaaagt ccattactgg attagtttga atgaacaaaa
    36841 tatcttcact tcattaggtt atttgttagc agcacatccg ccaggtgtga cagacccgaa
    36901 acgaatgtat gaagttaacc atattgctaa tttagcaaat gcatctgtca tcaataaatt
    36961 tcacgagtta gaaatgcctg gaaaaatcgg accaagcttt gcgtatacgc caaattatcc
    37021 aattgacagt aatcctgaaa atgttctggc tgctgaaaat gcagaagacc tgatggccaa
    37081 ttattggatg gatgtctata tgtggggaaa atatccgatt gctgccatga ggttcttaga
    37141 agaaaaagga tgggcaccaa cgattgaagc tggcgatgca gaattgctag aatctgctaa
    37201 accagatttt cttgggatca attactatca aacggcgacg aatgcattca atccattaaa
    37261 cggagttggt gctggaaaaa tgaatacgac aggaaaaaaa ggttcatcag aagaaactgg
    37321 agttcctgga atgtataaaa aagttgagaa tccatttgtc gaacgaacaa attgggactg
    37381 ggagattgac ccagaaggat taaggatcgg actgcgtcgt atcacaagcc gttaccgcat
    37441 gccggtactg attacggaaa atggcttagg agagtatgac aagttgacag aagataaaca
    37501 aatccatgac gactatcgaa tcaattactt acaaagccac gtcaaagcca tcaaagaagc
    37561 aatttcggat ggagcagaag tcctaggcta ttgcacctgg tcttatacag atttgcttag
    37621 ctggctgaac ggttatcaaa agcgatatgg atttgtatat gttgatcaag acgaaacaca
    37681 agaaggatct ttggaacgat ataagaaaga cagttattac tggtaccaaa aactgattga
    37741 agaaaatgga gagaaccttt agttcacata cttaaaacaa gaaggtacgg ctggatatgg
    37801 ccgtgccttt tcttgataaa atcatttaga aattaagaaa aactgtaaaa taagctgaaa
    37861 aatgaaagaa agcgtcagtt ctttcaaaca aaactttagt tcccttactt ttttttgtat
    37921 aatgaaactt gatgaaatga gggataataa atggcacaaa agaaacggcc tactaaaaaa
    37981 aggaaaaaga cgaaaaaaac gaaaaagcaa aaacagcagc aggaacaaat gctgacgatt
    38041 ggtgttgggt ttgccttgat tttatttgct gtcttcggct ttttaaaatt aggtttttta
    38101 ggaatattga ttgcaaacgg ctttcggatc attgcaggaa atacttacca aatcctctgt
    38161 cttttattag ccgtattagg attttggatt gtcattaaga atacagagtt ttcaattggt
    38221 aaaaaccgac gctggtttgg cggcatactc ttttatttcg gtatcttatt attgttacat
    38281 gcccatttat ttggcaaact ccatactggg gaaccaaata tcatggggac gacatgggat
    38341 ttgttagcca gtgatataaa acaaagtcaa gtagacaata acgttggtgg tgggatgatt
    38401 ggagcaatcc tttatcattt tacttacttc ttgattgcac agcctggaag ttatttagca
    38461 gcagtgctat tactggcagg aggagcattc ctgttcagta atctggaagg ctatcagctg
    38521 ttaaatggta tccaatcaat tggagaacga gtacaggaat tattggaagg tgatcctgcc
    38581 aagcaagctc gaaagcaagc ggcaaaggaa gagagaatga aacagcgcgc agaagcgaaa
    38641 gaagcaaggc gcttagctgc aaaagaagct gcagaaaaag aagctgcaga atatgagaag
    38701 aaaaaagcgg tgagccagca aagggaaaat actgctgatg aatggcagga accagaaaat
    38761 acagagccgg agcagctaag ttttgttcca atcgacagtt ttcaagaaaa tatccatcct
    38821 gcgaatctag agaaaccagt accagataca ccaaaacaga ccaatacagc agaaggtttt
    38881 tcagatgagt tgccagagga tgacggtacc tcattagaat ttgagattga agcagaacag
    38941 gaaaatcaag actatgaatt accgacagtt gatttgcttg attctatacc aactgtggat
    39001 caaagtgatg agtataaaaa aattgaaaaa aatatcggcg tattagaaca aactttccaa
    39061 agtttcggtg tcgatgccaa ggtcgtcaaa gccagcttag gaccatccgt cacaaaattc
    39121 gaagtccagc cggctgtagg ggtaaaagta agtaaaattg tgaacttaac agatgatatc
    39181 gcgcttgctt tagcggcgaa agatgtccgg atggaagcac cgattccagg taaatcactg
    39241 attggtattg aagtaccaaa tggaaagatc agtatggttt cctttagaga aatcatcgaa
    39301 gcacaaccaa accacccaga taaattacta gaagtacctt taggacgtga tgtttctgga
    39361 cgggtacaaa cggctgatct ttcgaagatg cctcacttac tcgtggctgg ttcgactggt
    39421 agtgggaagt cagtagcaat taatgggatt atcacaagta tattaatgcg tgctaagccc
    39481 catgaagtaa aactgatgat gatcgatccg aaaatggttg aattgaatat gtacaacggc
    39541 atacctcatc tgttgacgcc ggtcgtgacg aaccctagaa aagcagcgca agccttacaa
    39601 aaagtagtac aagaaatgga agaacgatat gaaaaattcg cggcaaccgg agtaagaaat
    39661 atttctggtt acaatgaatt tgttcaacag aaaaacttgg aaaacggaac gaaacatcca
    39721 accttaccat tcatcgtagt gatcgtagat gaattagctg atttgatgat ggtagccagc
    39781 aatgaagttg aagatgcgat tattcgttta gcgcaaatgg ctcgggcagc ggggattcat
    39841 atgatcctag ctactcaacg tccaagtgtg gatgttatca caggaatcat caaagcaaat
    39901 gtaccttcca gaatggcatt tgcggtatca agcggtacag attctcggac gatcattgat
    39961 tctaatgggg cagaaaagct cttagggcga ggagatatgc tattcttgcc aatgggtgag
    40021 aataaaccga tccgtgtgca aggagcattc atttctgacc acgaagtaga acgggtcgtt
    40081 caatttgtta cagatcagca agaagctcat tatgaagaga aaatgatgcc gacagatgaa
    40141 gttgaaacga caggtgctcc agaacagcca caagatgagc tgtttgaaga agcaaaagca
    40201 cttgtcgttg aaatgcaaac ggcaagtatt tcccttctcc aaagaagatt tcggatcggt
    40261 tacaaccgag cagcacgttt agtagatgaa ctggaagctc atggagttgt tggcccgtca
    40321 gaaggaagca agcctcggaa agtattcatt gagcaggaag aaacatcaga aacgttgccg
    40381 gacgataatg acatgtaaaa cttgtgtgat gaagggttga aaaacgaata accaataaaa
    40441 agacaaggca tgatgatacc aaaagaaaaa atggtttttt tccatctttt ctaatacggt
    40501 atgatgtctt gtctttttag tttttgtgag attaaagttc tattcgattt atttgtgaag
    40561 tattgcatta aggaaatgaa tcatgtatag tatgtagcga aactttgaga aaaagaggga
    40621 aaatactttg gaaaaacagt ccatttatgg cttgacgaat gaagaattaa tcaattggtt
    40681 tatagaaaac ggcgagaaaa aattccgagc tgcccaagtt tgggaatggt tgtatcaaaa
    40741 acgtgtaagt aatttcacag aaatgacgaa tctatcgaaa caattgatcg aaaaattatc
    40801 ggagcatttt atcatcaatc ctctaaaaca gatggtcgtc caagaagctt cggatggtac
    40861 agtaaaatat ttgtttgaac tccctgataa aaacatgatt gagactgtac tgatgagaca
    40921 agaatatggc ttgtcagttt gtgtgacgac acaagtagga tgtaatatcg gctgtacgtt
    40981 ttgtgcaagc gggctgctca aaaagaaccg tgatctgact gctggagaaa ttgttgcaca
    41041 gatcatgatg gtccaacatt attttgatga gcgcaatctt ggcgaacgcg tttcacatgt
    41101 cgttgtaatg gggatcggtg agccatttga taattacgac aatgtaatgg actttttgca
    41161 tatcatcaat gatgccaaag gattggcaat tggtgctcgg cacattacag tttccactag
    41221 tggattagca cacaaaatca aggaattcgc taataacggc ttgcaagtca atctggctat
    41281 ttccttgcac gcgccgaata atgaggtgcg aacatcgatc atgcggatca accgaagttt
    41341 cccaattgag aaattgatgg aagctgtgga tgagtattta gagaaaacaa accgtcgaat
    41401 cacgtttgaa tatatcatgt tgaatcaagt aaatgataga ccagagcatg cgcaacaatt
    41461 agcagatcta ttaaaagata agaaaaaatt agcatatgtc aacttgattc catataatcc
    41521 agtcagtgaa catgatcaat attctcgcag tccaaaagct gatgtattga gattttatga
    41581 tgtattgaag aaaaacggcg taaactgtgt gatacgtaaa gaacatggta cagatattga
    41641 tgcagcttgc ggacaattgc gaagcaagca aatgaaaaaa acagttgcca aataatcgta
    41701 tcctactcgt tttttcaatt accataaaag gagcagtttt cttaattaag gaactgttca
    41761 acttaaataa gagaaaagat tctatagcga aagctataaa gctttttttg acaagaaaaa
    41821 ccctcatcaa gcaaagaaat gtcctcaatt tgatgacagc ctgcttgatg ggggttttag
    41881 caattattta actgattttc ttatatcctt gctggctttc ttgtgtagca tgataagttt
    41941 ctacgtcaag aatggcctgt ttaaattttt ctcgggtgat ttcataaggc acatgtttaa
    42001 tatcatttgt tgccatggct ttatctaaga ttgcttctaa atcggtcgtg acattgagat
    42061 tcatgtcggt taacgatact ggaagttggt tctttttcat aaacacatag attttatcaa
    42121 acaaatcgaa ctgctgatcc atcatcaata aggtcagtac accataactg acagatgctc
    42181 cgtgaaggta tccctccatt ttttctagaa cagtcgtacc gtaatagaat gagtgtgcca
    42241 tagcagaatt atagttattg ttaactaaaa cagaaaccaa tccggtagta acaatgatat
    42301 ccgaaacgac ttgttcaatt gcatatgagg gacgatcgtc ggcactatct ttcaatgctt
    42361 gcgtaccata agtcaagaga cgatcaatgc acatttttcc gatttggatt cctaatctat
    42421 ccgtgtagcc tagatcatcg ccacgagcag aaaaagtaga ttcgacttct ttggataaag
    42481 catcgccaat acctgcccat aagtatttat caggtgcttc ggcaataatt gctgtatcaa
    42541 tgaaggtgtg tacaggtggt tttgaaggaa agaagagtcc gtccattacg ccttcttcgt
    42601 tatagatgac acataccgca gtgacgggcg aacagttcga accaatagtg ggaaaggtga
    42661 agactggttt agctagtttt tcaccaatga cttttacagt atcgcaagca cggccaccac
    42721 cgactgcaaa caggacgtct gctttttgga cactttcatg ctggatcaac tgttcaatat
    42781 ttccataagt tgaattaccc ccgtaccaga gactggcgac aacctctatt tcctgtgtca
    42841 aagctacttt tattttgttt tctgcctttg aaagtgcagt cttccctcca atcagcacta
    42901 cttttgtccc atattctttg acgattccat ttgctttttc atacgcatct gttccaatgg
    42961 tataatttgg taagaaaaca ctttgactca tattc
//
LOCUS       DAKCAA010000018        42615 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000018 DAKCAA010000000
VERSION     DAKCAA010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 42615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.018"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(84..1031)
                     /locus_tag="OUE31_001094"
     CDS             complement(84..1031)
                     /locus_tag="OUE31_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCU0222115.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            1277..1741
                     /locus_tag="OUE31_001095"
     CDS             1277..1741
                     /locus_tag="OUE31_001095"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HCU0222116.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQQILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(1803..2846)
                     /locus_tag="OUE31_001096"
     CDS             complement(1803..2846)
                     /locus_tag="OUE31_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HCU0222117.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGIKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLFYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(3346..4311)
                     /locus_tag="OUE31_001097"
     CDS             complement(3346..4311)
                     /locus_tag="OUE31_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HCU0222118.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            4545..5390
                     /locus_tag="OUE31_001098"
     CDS             4545..5390
                     /locus_tag="OUE31_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCU0222119.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEIANSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            5581..6768
                     /locus_tag="OUE31_001099"
     CDS             5581..6768
                     /locus_tag="OUE31_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCU0222120.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            6774..7130
                     /locus_tag="OUE31_001100"
     CDS             6774..7130
                     /locus_tag="OUE31_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HCU0222121.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            7132..7470
                     /locus_tag="OUE31_001101"
     CDS             7132..7470
                     /locus_tag="OUE31_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HCU0222122.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    7546..7802
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7865..8899
                     /locus_tag="OUE31_001102"
     CDS             7865..8899
                     /locus_tag="OUE31_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0222123.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            8892..9578
                     /locus_tag="OUE31_001103"
     CDS             8892..9578
                     /locus_tag="OUE31_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222124.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            9602..10450
                     /locus_tag="OUE31_001104"
     CDS             9602..10450
                     /locus_tag="OUE31_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCU0222125.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            10647..11420
                     /gene="sufC"
                     /locus_tag="OUE31_001105"
     CDS             10647..11420
                     /gene="sufC"
                     /locus_tag="OUE31_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HCU0222126.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            11433..12719
                     /gene="sufD"
                     /locus_tag="OUE31_001106"
     CDS             11433..12719
                     /gene="sufD"
                     /locus_tag="OUE31_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HCU0222127.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            12716..13951
                     /locus_tag="OUE31_001107"
     CDS             12716..13951
                     /locus_tag="OUE31_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCU0222128.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAH
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     SFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVINPVQELAELVHENGGVIVVDGAQSAPHMTIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQELGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VIAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFKHGTI"
     gene            13938..14408
                     /locus_tag="OUE31_001108"
     CDS             13938..14408
                     /locus_tag="OUE31_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HCU0222129.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            14413..15804
                     /gene="sufB"
                     /locus_tag="OUE31_001109"
     CDS             14413..15804
                     /gene="sufB"
                     /locus_tag="OUE31_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HCU0222130.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(15899..17041)
                     /locus_tag="OUE31_001110"
     CDS             complement(15899..17041)
                     /locus_tag="OUE31_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCU0222131.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(17080..17814)
                     /locus_tag="OUE31_001111"
     CDS             complement(17080..17814)
                     /locus_tag="OUE31_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0222132.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIIEEFDNNILLLTSSIEEQLEEMIDEGIHSQVEDMNYPEEAVNEIIDN
                     INKLKQTISSIGKKYTKKKMKGGDTI"
     gene            18049..18324
                     /locus_tag="OUE31_001112"
     CDS             18049..18324
                     /locus_tag="OUE31_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222133.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMEQYKG"
     gene            18422..20419
                     /locus_tag="OUE31_001113"
     CDS             18422..20419
                     /locus_tag="OUE31_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222134.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSVEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(20495..20830)
                     /locus_tag="OUE31_001114"
     CDS             complement(20495..20830)
                     /locus_tag="OUE31_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0222135.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            20957..21172
                     /locus_tag="OUE31_001115"
     CDS             20957..21172
                     /locus_tag="OUE31_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0222136.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            21209..21571
                     /locus_tag="OUE31_001116"
     CDS             21209..21571
                     /locus_tag="OUE31_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCU0222137.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADEVKKSTEQTFS
                     EMKEQIVHGQETGKLYLIIGWVSMVVSLAFIPVVFGAVAVIMGYLYRETDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            21617..21943
                     /locus_tag="OUE31_001117"
     CDS             21617..21943
                     /locus_tag="OUE31_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222138.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            22144..22920
                     /locus_tag="OUE31_001118"
     CDS             22144..22920
                     /locus_tag="OUE31_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222139.1"
                     /translation="MMKKNYLKTGIFLVIGTILVIQLSGCRNKDKDFYGYWSGTAEKI
                     PVDYNFKITKDRVIELQKNGEMVDFKYTLRHKKFDSTTFRSIMISKDELVKAIPELKE
                     TTGISNITFMPIDGEKDKLTVLVNLDEHLSTATLYRTTKDESPIGKVEKKNDTISRQT
                     VDKKIDTFIKTYAAIPPTWKLVNEDKGITINTDTEIPTDAQSLSDLLANLTGVSNAVS
                     EQVGKDIPLRLLENGKKDYSVVFKNGKVTDYNEIFEKVIE"
     gene            24694..25461
                     /locus_tag="OUE31_001119"
     CDS             24694..25461
                     /locus_tag="OUE31_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylase"
                     /protein_id="HCU0222140.1"
                     /translation="MVEEEQGRLIKSKKRVQKHGEVFTPQRTVKDMLDLPGIKEACEE
                     LQTTFLEPSAGEGAFLVEVLTRKMAMVAREYNESLEQYENYSLLALSTLYGVELLEDN
                     AQTCVMNMFQVFNDLYREQSKKHGTAMKRKVQDSAKTLISRNIKQGDFLTKRTPDDNP
                     IIFSEWTPKTLRKGQKKITVNRTEYSLEDIYSGVTREFGEAYSALPVFEQLDLFSFDD
                     EVDEEVSNDPILRYVAMPITEVYKEEMEEIDDDSVEI"
     gene            25439..29836
                     /locus_tag="OUE31_001120"
     CDS             25439..29836
                     /locus_tag="OUE31_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019788126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HCU0222141.1"
                     /translation="MTTALKSKAKYFDYLPKYGSKLEHFLGIPNLVDAINTYRVTVNQ
                     IPNEVAIGTRRYSEVAARKIASNVGIDQQSMKYVDVLRELRVRNNITPTIADLFHKLR
                     KYGNVAAHENGIIPVSEAVESLVTLDTLLRVFARNLSGDKSLNPKEEITDEMFVITYN
                     TFDRKLIYIQSAKDADGTWKMYQGLEKIGDASVPENYEADFTPNSEYLREYASRRIKQ
                     YMTTAGVPFVLHWAQLAVNKKNQFFRDHDVHEVLKRSGYNPQTIGEDDTGKPNEWFSV
                     TVDVAKKAIQAVKDGKGSLDSEKDDFDEFKINFRPEQKDAIEQTKTVFKTKDEMLWNA
                     KMRFGKTLSSLQVIKESQYKKVLIMTHRPVVSDGWFTDFKKIFTDGSYIYGSKQDGEK
                     IQNLVDTEKPFIYFASIQDLRGSEWAGGKAGDKNYEFLAIDWDFIIIDEAHEGNETEL
                     ANNVKAKLRKEHTKVLELSGTPFNLFDKYDEDNIFTWDYTMEQEAKEKWSVEHPNEPN
                     PYEGLPKVSMFTFEIPNKFDYFDENKAFNFREFFRVKEDDETKLLHEGDVRKFLDYIT
                     TNDEKTNFPFSKPEFRENLRHTLWLMPGVKEANAFERVLETHPIFKDYNIANVVKTGD
                     SEHASDSDLELVRKAIGNPAKSKTITLTVRKLTTGVNVPEWTGVFFLSNTESPTSYLQ
                     AAFRAQTPFNHAELGIKKNCYIFDFAPDRALKIMSGSVGLTSKKGKVNSSEQKKKLER
                     MLNFLPILGKQGNVMKEFSVDRMLTALKKAYAEKAVRTGFEDSSLYNDNLLNLDQADL
                     TKFEDLKKIVGSSKPTKVKDFIVSDNGMSEEEYEKASRAEKKPKRQRTKEEQEAIDRA
                     KRLREQRNKMISILRGVSIRIPMMIYGMDIDIKDDVTIEMFLNLVDEASWNEFMPEGL
                     SKGRFREFIEYYDADVFVEAGRIIRRRAKSYDELDVIERTRKIGELFSTFKNPDKETV
                     LTPWRVVNMHLGNTIGGLSFFDEEYQNSTENGQPIVRWRKTDCTDDIFKENRKILEIN
                     SKTGLYPLYAATSMYYVQLLKQSDINAGRVDSEAIWEKVLSEQIFVISKTPMAKTITK
                     RTLIGYNAWKVNVEYSSELVTSMKRSINDGLTNLKGVYKNVKFDVIIGNPPYQEKDGG
                     SGASATPLYNLFVETSVKLSERYVSMITPSKWFAGGKGLDKYRDFMLNSSSLKVMVDI
                     VNGKEIFPNTSIGGGVSYFLWDKKYNGLTQYTNQHDGVSNTQERKMNEFPVFVRYNEA
                     ISAIHKIGEHASVGDFVISRNPFGLPTKIRGEEVQDSRNSIKVISSGGVGFVPLEDIT
                     KGQDMVGKYKVISSSLTSEHAGEPNKNGMFKVISTNRVIKPNEVVTDSYLVLFSADTE
                     TEAINYLKYLRTRFYRFLLLQAVTSIHLSKDKFMFIPVQDFTSGSDINWNVGIEEVDM
                     QLFKKYSFDASEILFIDQTIVPILHEEYY"
     gene            complement(31276..31941)
                     /locus_tag="OUE31_001121"
     CDS             complement(31276..31941)
                     /locus_tag="OUE31_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222142.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            32121..34103
                     /locus_tag="OUE31_001122"
     CDS             32121..34103
                     /locus_tag="OUE31_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HCU0222143.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            34107..34745
                     /locus_tag="OUE31_001123"
     CDS             34107..34745
                     /locus_tag="OUE31_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222144.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            34773..35201
                     /locus_tag="OUE31_001124"
     CDS             34773..35201
                     /locus_tag="OUE31_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222145.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            35658..36569
                     /locus_tag="OUE31_001125"
     CDS             35658..36569
                     /locus_tag="OUE31_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCU0222146.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            36786..37223
                     /locus_tag="OUE31_001126"
     CDS             36786..37223
                     /locus_tag="OUE31_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222147.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            37318..38202
                     /locus_tag="OUE31_001127"
     CDS             37318..38202
                     /locus_tag="OUE31_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCU0222148.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            38426..41593
                     /locus_tag="OUE31_001128"
     CDS             38426..41593
                     /locus_tag="OUE31_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222149.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSKYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            41613..42158
                     /locus_tag="OUE31_001129"
     CDS             41613..42158
                     /locus_tag="OUE31_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HCU0222150.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            42186..>42615
                     /locus_tag="OUE31_001130"
     CDS             42186..>42615
                     /locus_tag="OUE31_001130"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HCU0222151.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI"
BASE COUNT        14344 a         7104 c         8792 g        12375 t
ORIGIN      
        1 tttattcgga aaaaaggact gtgacaagac ttttgtcaca gtcctttttc atttaaaaaa
       61 atgtttactt catttgacgt atattattgg tgaggcttca attcatttgg cttcactttt
      121 tctgtttctc ttatgatata aacaggacgc tgtttcgttt ctaagaagat tttcccgata
      181 tatttcccga tgattccaag acataacaat tggattccac caatgaacag gaagatcgag
      241 accatggaag gccatcctga tgtaggatca ccaaacaaca atgcccgcaa aataatgaac
      301 aaaattgcaa taccagaacc gacacaagac aaagcgccga taaatgaagc aatcgttaac
      361 ggtgcatccg agaagttcac gataccatca atcgagtagt tgaataattt ccagaaggac
      421 caagatgttt cgccagccac acgttcgcgg ttttcataag aaatatattc tgttttaaac
      481 ccgacccagc taaataatcc ttttgaaaat cggttgtatt ctgttaattc taggacggca
      541 tccaccattt gacgagtcat caagcggaaa tcacgagcgc catcgaccat ttctgtatcg
      601 ctgattttat tgatcaactg gtagaatttt ttcgcaaaga aactgcgtat cgcaggctcg
      661 ccttcacgag tcgaacgccg ggtgccgaca caatcgatat cagaagtagt gatccggttg
      721 atcatctcag gaagcaattc gggcggatct tgcagatcaa catccatcac ggtcactaaa
      781 tctcctgtag aagcttgcaa tccagcgtat agagccgctt ctttcccaaa atttctggaa
      841 aatgagacaa agcggacata aggataagct gaggctagct tcttgattgc tgctaacgta
      901 ccgtcttttg atccgtcgtc aataaacaaa tattcgaact catgggcacc tttgaatttt
      961 tcaacctcat caaaaaaaag aggaacagtt ttttcttcat taaaacatgg gacaacaatt
     1021 gatactttca tcgtttctat cctttcaatc gtatgtttat atatggttta cattcaaaat
     1081 ttaataaacc ttaaataaca cctttaaaat ttgattttac gtaaaagaac aggtattctt
     1141 tttgtaaact aacgtattta gtttaccatg tttcctcggt ttatcaaact tttaagaaca
     1201 atttttatta gttggcaagt agttttggat agagaaaaag gaggaagttc cagtctattg
     1261 actagaagca aacaaaatga aaatacacac acctatcggc tttttatggt tagatgcaga
     1321 tgaatccgga ttgactgctg tatcttttca gccaatttca gaaagcgaat cagcgaatca
     1381 gcaaatttta acgcgcacac aagaacagtt tgaagaatat tttgcgggaa aaagaaaaga
     1441 atttgatgtt cctttatcta taaagagagg tacgcctttt cagcaaaatg tctggaaagc
     1501 tttgtcgacc attccttatg gagaaatccg aacgtataaa gaagtagccg ttgctgttga
     1561 tagtccgaaa gctgtgcgag cgattgggca ggcaaatcga accaatccat tgccaatcgt
     1621 tattccttgt catcgagtga tcgggcaaaa tggaaaactg acaggatata tgggaaacgc
     1681 aatagatggg gttgaaatca aacgccaatt gttgttgtta gaaggatatc tgcaaaatta
     1741 aaaacagttg tgattcggac attgttccat gcgagaatca caactgtttt ttcatgttca
     1801 ttctaaactt tgatcagcca aataaatagt aaagccatca ctgtttggag aagcccgaca
     1861 gctaatccat aaaataagaa gcgtgtacct tctttcatga attttgcaaa gtctaaacgc
     1921 agaccaattg ccgctaaagc agtgatctca aaccagctgc tgataaaatg tgccgattgg
     1981 tcaataacta caggtaaaga aaacaagctg ttgaccaaac aaaagatcac aaaccctaat
     2041 acataccaag gaagtggtaa ttttcgtttt ttctgcgtat cagttggcgt ttcaaacaga
     2101 gctggttgtt tcttgtgcat gaatttttca aacagataga caacaacaac gagcatcata
     2161 atacgtagaa tcttaaatag catggcgaat tcgacaacag aattgtcaag taagcttgcc
     2221 ccagcgacta cttgaccaac agattggagt gtgccaccca aaagtgcact tttttcaatg
     2281 agatttccac caaacaactg taatccaaga aaagggagag tcaacatcat cacagtaccc
     2341 agtagattga ctagtgtgat gatctgtcct ttttcttcct ctttcgcatg gatggaaggg
     2401 gcgatcgaag caatagcaga agaaccacaa acagcgtttc ctccagccat catcaaagaa
     2461 gaagtatcgc tgaattgcag ttttttacca atcaagtaag caccgatgat agtgactgac
     2521 atttgcagta acacaaaaac aattcctttt ataccaattt gagcaatcgt ttgagctgtg
     2581 acagttgcac ctagtaaaaa aacagagaat tctaatagtt tgctttcagc aaattttgtg
     2641 ccgattgcta gaacaggctg tttaaaaaaa gtatttccta ataaaatacc caataaaata
     2701 gcaatagtcg ctccacctaa ctgtggcaga taaatagcaa gaagcctgct gaaggcagcg
     2761 atggcaaaag aaagcagtaa accgggtaag atttcgcgga ccgctgaatc ctttacagat
     2821 tttattggat gtgacaatga tttcatttga tcggttcctt tcgtcaataa atactaaaag
     2881 catactcgaa catagtagca ctaaaccagt attttgacaa aagaacaaga ggtcgtgaca
     2941 aaagtcttgt cacgacctct tgtttcgaat aaacggtgtt caaaagccag tttctcggta
     3001 ttaagccaaa tttatgcaaa aatgtggaaa gccattttca caaaattttt cttaatactc
     3061 gaaactaagc ggctttttca cgacctcttg gtaaacggtg ttccagaagt agcttcttcg
     3121 gaaataagcc gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt
     3181 cttgaagctg accacttctt ttacgacctc ttggtaaacg gtgttcaaaa gcttgcatct
     3241 gcggtaataa gcccaaccag tacaaaaaca tgaacagctg tttttgtttg gccgttctta
     3301 ttacttgatg cagaacagct ttttcacaac ctattgaatc gattattaag cgattttttt
     3361 agaaacaaat tttccatgtt tgctatgttc tttaattaag aaacgtacgt aatgagcaag
     3421 aacgtagaag acaactacac ttgcaaacag acattccgca acttttaaga aatccaatac
     3481 gctactatag atacctaaac tgttgaagta atgaacagta gtaaatatag ctgttgcaga
     3541 gataacaagc gggaatgtaa aggctgcata gcttggataa aaacgaagct tgaacaaacg
     3601 tggaagcata gacagcacaa cgaaatacaa tacttgagat aaagcgaaca atgctacgac
     3661 aagataaaaa ttaggttcag caaagttttt aagataacct gttaggcaaa gagaaccagg
     3721 tgctgcaacg atcgtaatca gcggacgtgt cggatgagcc atatttctta cgaaaaagac
     3781 acgtttgatg atgatcggca ataagaacgc atagcagatc aatgaaatcc aaaagaaaat
     3841 ttttccaata agcgggaaga agttcccggc agttacagtg atgaccccaa atccaacgta
     3901 aatgataaac cagcttggat aaattgcttc aattgaaaga tcagctttga taacatggtg
     3961 ataattgaaa taaaagacaa ggatcacttg gaagataaca gcgcacagcc aaatgaattt
     4021 gacaattggt gcaatacttt catatgaaac aaaataagta caaataacca tgagtgacat
     4081 cgtaaaagtt ggtgaaacgg aggcgatgat tggatcatgc aacgtttgtt tcgtgtgttc
     4141 gaataagata aacaatttaa caaaaatgaa tatcataaga atcatagaga taccgccagt
     4201 tagattgcct aaagcaacat ggtgatagtc tttaaacaga tttccaaggg aagctaaccc
     4261 aaggatcaac ccgcagatcg ggatcggaat aattttcaaa aagttcttca tatataatat
     4321 tctccttttt atttaataga ttttagtacc aagatgaacg aatacattgt aaaatgaata
     4381 ggaatgtatg attacgagca agcagacagc tgattgtctt catctaagtt actagttgga
     4441 tcagcaactg ttttgttgta catttctatt atagatggtt ttttgtatat ttaaatcaaa
     4501 tagtttttat agtaattatc ataaaaagtt atggaagtgg tgccatgttt aagttattaa
     4561 cgacttttcg agcagtatat gaaacaagaa atttttccag agcagcagaa gtactgtttt
     4621 tatctcaacc agcagtctcg aatcaaatca aacagttgga gcgggaattg aatatcgatc
     4681 tttttcaacg taacggaaga aaagagatgc ttccaactaa gcaagccgac ttattatatg
     4741 aacggacact ggttttgtta gaagaatggg aagaaactca gcaaaaattg ctcaatgaac
     4801 aaaatgaaga agaagtatgt cggatcgttg cttcccacac ctttgctgtc tatcttttgc
     4861 ctcagttgat gaaacatctg atcaaaaggt ttcctaaagt gcattttgag atcgaaatcg
     4921 cgaattctca tgaatcatta gaacaagtag cgaaacatga atccgatttt ggttttatcg
     4981 aaaagccatt agagacttcc ggcgtacaaa gatactcttt gatggaagac cagctagtca
     5041 tcgctgggga cccaaaaagc aaattgtggc ttgtaagaga agcaaactct ggtgtttttc
     5101 attatacgca gcgttatttt gaagagatga atatccaaga taagaagatg atcgtgaaaa
     5161 gtaacgatgt aattgttgcg ttgctgaagg aaggaatcgg tcgctcgatt ttgtctaagc
     5221 gctctgttcc agaaaatgtg ccaatgactc cgttgaattt ccatcgatat ttttatttca
     5281 tccaacgaac caatctggtt tctgatcagc tgctagagat tgccgaagag atccttcgat
     5341 acaatgaaag cacagaaact tctcacagcg aggagaatct cagctggtag ataattgcat
     5401 gtatcaaaaa aagttctatg atacactaaa gataagcagt aggcttttgt actgcatttg
     5461 ctcaagcaac tgcacaaacg gaaagttaat ttttcccaaa tgtctatgga aagactttcc
     5521 attatctaac tggaccgcta taataatcag cagtatggtt tttaagaaaa gggatgaaac
     5581 atggaaaaaa aattaaaagc ttcgaacgat aatcgtattg attatggcgt gattttacca
     5641 gtctttctgt tatgtttgat tggtctgctc tcattatatg tagcacttag ccatgatccg
     5701 aacaatccag cagtcttgaa aggcgtaggg atgcaagttg tctggtattt agttggagcg
     5761 gcagcaatcg ttgtcatcat gcatttgaat tccaaatgga tctggaaact gactccttac
     5821 ctttatggtt tggggttagt ggtaatggga ctcttgctca aattctatga tcagaattta
     5881 gctgcttcaa cagggtctaa aaactggttt cgattcggtg cgtttacttt ccagccagca
     5941 gagttgatga agattgcgta catcttgatg atggcactga tcgtaactaa acataatacg
     6001 caagtaaaag aacggacgat gaaatcggac ttttggctga ttgggaagct cttgatcgtg
     6061 acaataccgg ttttagcatt gatcatggcc caagatgact ttggaacgat gcttgtcttt
     6121 cttgcgatct ttggcgggat tttcttgatg tctggaatct cttggcgcat catcgcacct
     6181 gtagtaatct tggcagtagt cgttggagca ggaacgatct tcttggttac gactgaaggc
     6241 ggaagagact tgctttacaa agttggcttc aaatcttatc agtttgcacg tattgattca
     6301 tggctggacc ctttccatga tacgtcagga atgagttatc agccggccca aggacttttg
     6361 gcaattggta ccggtggctt gtttggtaaa ggattcaacg taagcaatat ttatgtgcct
     6421 gttcgtgagt ccgatatgat ttttaccgtt atcggtgaaa acttcggctt tatcggtggt
     6481 gcattcgtca ttttcttgta ttttatttta atctatcgta tgattcgggt gtgtttcgat
     6541 acgaataatg aattttacgc ctatatcgca agcggtttga tcatgatgct gctgttccat
     6601 gtctttgaga atattggagc aaatatcgga ttacttcctt taacagggat cccattgcct
     6661 ttcattagtc agggaggatc ttcgatttta gggaacatga tcggtatcgg gttgatatta
     6721 tcgatgagat accaaaatga agcacctgca agatcttcaa ggaggtaaga aaattgtaca
     6781 ccttttactg gtacccgaaa tgttcaacat gcaaaaaagc caaagcgtgg ttagaccagc
     6841 atggcgttag ttatcaaact gttgatatga tcaaagaagt accgaaggcc tcaacgattg
     6901 agacttggct agaaacgagt caagtaccaa tccgtcgcct gttcaacaca agcgggatga
     6961 aatatcggga acttggactg aaagatcaag taggcgagtt tacggcttca aaagcgagcc
     7021 aagtcttatc gacagatggt atgctgatca agcggccact gatcttacga gaggaccagc
     7081 ttgttgcaat tggattcaat gaaaaaattt atgaaggaga actgatataa aatggcaggc
     7141 aagcatttga agaaaaagga caacctttgg atcttattta atggaaaaga atactgtgtt
     7201 ggtttgacaa atgaagcgca agaagaactt ggagacatca cgtttgccaa tctgccaaaa
     7261 gcaggacaat cgctaaaaaa agatgaacct ctgatcgaag ttgaagcgga aaaagcggtc
     7321 aatgaatttg ccagcccgct aacgggtaca gtttcttctg ttaatgataa aatcggtgaa
     7381 gatatcaata tcttgaatga ttcagatgaa atgaatgcgt ggatcttaag tttcaaagat
     7441 gttgatccaa aagaatttga cgaattataa aatcagaaaa tcacttgaaa aaagttgaca
     7501 ctgattcttc cagttgctat aatcataagc aatcctatat gaaacgagaa agctttgaaa
     7561 agaagagtac atgtcacgga cgtttgaaga gagccctgtt tgctgaaaat gggtaacgaa
     7621 aatgagatgg aagatggtct tagagcagag taagcgagcg taagcaaact tactacggga
     7681 gtgcccgtta cagcgcgaca gtatacggaa agaagctaag tccaagtact ggaagaggct
     7741 gttattgcga agtaacggta aatcaaggtg gtaacacgga agttcaagct ttcgtccttt
     7801 tgcttaaggc aagagggcga aggctttttt gtttgaaaaa tcataagaga aagatgtgaa
     7861 tggcatgtca ttaatccaac taacgaatgt caaaaagaca ttcaatggga aaaacggaaa
     7921 catccaagcc gtcaatgacg tttcactaaa cgttgaaaaa ggggatattt atggaatcgt
     7981 cggctattct ggcgcaggaa aaagtacatt agtccgtctc ctgaatggac ttgagcttcc
     8041 cacgagcggc gaagtgatcg taaacgatca agatattaca aaattaaaaa acaaagaatt
     8101 acgtacattc cgaaagaaaa tcggtatgat cttccagcat ttcaacctgt tatggtcaag
     8161 aactgtactt gaaaatatcc agctgccgct ggaattagct ggcgtaccaa agagcaaacg
     8221 taaagaacgg gcagaagaac tgttgcgttt agtcgggtta gaaggacgcg gacaagcata
     8281 tccttcacaa ctttccggcg gacagaaaca acgcgtcggt atcgcacgag cattggcaaa
     8341 tgatcctgag atcctgcttt gtgatgaggc tactagcgca ttggacccgc aaacaacaga
     8401 agaagtatta gacttattgt tagcgatcaa taagaaattg aatttgacca tcgtcttgat
     8461 cacacatgaa atgaatgtga tccgcaaaat ctgcaacaaa gtcgctgtga tggagttggg
     8521 gaaagtcgta gaagaaggag acgtattgac tgtcttcaga caaccgaaaa aagaagtaac
     8581 caaacgcttt gtacaacaag acatcgaacc agaagctgat tcgacagaac tattagctga
     8641 actcatcaaa gaaaatccaa gcggccgttt ggcaactttg acctttagcg aaagaaatgc
     8701 caacgagcca gtcatttccc aagcgattcg acgctataac atcgatgtca acgttgtgta
     8761 tggaaagatc aaacaagtga aagaaggttc ctttggttca ttgactgtct tgatgactgg
     8821 tgaaaccaaa gaattagatc aagcagaagt gttcatcaaa gaacaaggag taggaattga
     8881 ggtgatccat cgtggataaa agcttttcag aaacatatct agattttaaa caaatcaacc
     8941 cggaaacgat gaatcaggct atccttgata cactatatat gacattaatc tcaatggtct
     9001 tagtgacgat catcggatta gttttgggat tgatccttta ctctattgga cgcaaaaaca
     9061 aaccgtatgc tcgaatcatt tatggaatcg tatcgatcat cagtaatatt ttccggtcaa
     9121 cgccatttat gatcctgatg gttttgatca ttccatttac taaagcaatc gtaggcacta
     9181 tgctaggtgc gcaagcagcc attccagctc ttgttttatc cgcagcacca ttttatgccc
     9241 gtctagtaga gattgctttt cgtgaagtca gccctggtgt actggaagca gcagatgcaa
     9301 tgggagcaag ttactgggaa atcatctgga aggtcttgat acctgaaagt attcccgcat
     9361 tgatttctgg attaacagtt acaacgatct cgatgatcgg atttactgcg atggccggcg
     9421 cgatcggcgc aggtggactt ggaggtcttg cttggcagga aggctaccag cgtggtaatc
     9481 tgacagtgac attcgttgcg actttaatta ttttactaat cgtatttatc gttcaaggaa
     9541 tcggtgattt cttaactaag aaaacagaca aaagataata ggatataggg ggatgtagga
     9601 tatgaaaaag aaaatttttg gatttgcagc agcgcttttg ctgactgtag gattagcagc
     9661 atgcggtaac aacagcgaca gcaaagattc agcaaataaa gcagacgaca cgacattgaa
     9721 agtcggcgct tcaccgacac cgcacgcaga gattttggaa catgtgaaac cattattgaa
     9781 agatgaagga atcgatcttg aaatcgtcaa attcgatgac tatgtattac cgaaccaatc
     9841 tttggaagaa ggcgacattg atgccaatta cttccagcat attccttatt tgaacaaaga
     9901 aatcaaagaa aaaggatatg actttgtcaa tgccggtgct gtccacatcg aaccaatggg
     9961 cttgtactct aaaaaagtca aagatgtttc cgaattaaaa gatggtgcaa caatcattac
    10021 ttcaaattct gaatcagact ggggacgcat catcacaatt ctacaagatg ctggcttagt
    10081 caaagtcaaa gatggagtag atctggaaac agcaacattc gatgatattg aagaaaaccc
    10141 taagaacttg aagttcaacc atacgatcga cccatcactt ttagcttcta cgtaccaaaa
    10201 tgatgaaggt gacctagttg caatcaacgc aaacttcgct tacggcgcag ggttgaatcc
    10261 attagaagat gccgtattgc ttgaaaagga caactctcct tacgtgaata ttattgcgac
    10321 tcgtaaaggt gatgaagaca gtgacaaaat caaaaaactg attgaagtgc ttcaccgcaa
    10381 agaagtccaa gaatggatca cagacaaatg gggcggctct gttaaaccag taaaggctga
    10441 tgcaaaataa ggtatggaac aaaaaagatg agaaataagt ctgtaatggc ttatttctca
    10501 tcttttttat acctattcta atttagaaat caaaattgtt taataataaa taaaagatat
    10561 ttgattttag taaggaaggt cattgcgctt cattctcaat tagtctaaaa tgagtgagaa
    10621 cgaaagagaa tttgggggta taatgcatgt ctgtcttaga aataaaaaat ctacatgtgt
    10681 cgatcgagga aaaagaaatc cttaaaggcg taaacctaac aatgaaaacc ggagaaatcc
    10741 atgccatcat gggacctaac ggcacaggaa aatctacctt atctgccgct atcatgggca
    10801 atccaaacta tgaagtaaca gaaggcgaaa ttttgtttga cgggaaaaat gttttagact
    10861 tggaagtaga tgaacgtgcg cgacttggct tatttttagc tatgcaatat ccaagtgaga
    10921 taccaggtat cacgaatgcg gaattcatgc gtgcagcgat caatgcgaaa cgtgatgaaa
    10981 acgacaaaat ttctgttatg gcatttttga aaaagttaga tgaaaaaatg gctttactaa
    11041 atatgccaga agaaatggct gaacgttatc tgaacgaagg tttttctggc ggagaaaaga
    11101 aacggaatga gatcctgcaa ttgttgatgt tagaaccaac atttgcaatt ttagacgaaa
    11161 tcgattcagg tctggatatc gatgctttga aagtcgttgc taaaggagta aatgaaatgc
    11221 gcggagacaa tttcggtgca ttgatcatca cccactatca acgattattg aactatatca
    11281 cacctgatgt cgttcacatc atgatggaag gccgagtagt catgacaggg aatgctgacc
    11341 tagctaaacg tctggaagca gaaggctacg ctggtatcag taaagaatta ggaatcgact
    11401 ataaagaaga agaagcgtaa gggggagcaa gaatgaaaga aaaaaactgg ctcgattatc
    11461 ttgacgcggt aaatgatttt tctttaagta aaggcgaacc tgattggatg agaaccttcc
    11521 gtcaagacgc actagcgaaa gcagatgaac tgccattgcc gcatatcgat cgggtgaaat
    11581 tccatcgctg gtcgttattt gatgtgaaag aaacacaaac catcagtgaa acaggcacga
    11641 ttccggcatt tgatgcaatg aaagacaatc ctgtgcttgt ccaacaaggt tcatggacga
    11701 tttttgaaca actgcctgtg gaattagcag aaaaaggagt catttttacc gacttgttca
    11761 ctgcaatgat cgaatatcca gaactagtcc aagaatatta tatgaaaaaa gcagtaaaca
    11821 tgaacgaaga ccaattgact gcactccatg tagcttttat gaacagcggt attttcctgt
    11881 atgtgcctaa aaatgtcgtg atcgatgaac cactcgagtc cttattcatt caagatggcg
    11941 catccgatga gcacttcttc aagcatgtgt tgatcgtggc agatgaacat agtgaatttt
    12001 cttatctgga acgtttccag acaaccaaag aacaagtagc aaaatcatca ggtaatatca
    12061 tcgtggaagt catcgctaaa gctggttcaa aaatcaaata ttcagccgta gatcaattag
    12121 gagaaaatat tacttcttat atgaatcgcc gtgggcacat tttacgagat gcttctgtcg
    12181 actgggcaat tggtgtcatg aatgacggtc atgtgatcgc tgactttgac tcagatttag
    12241 caggagaagg tgcacacgca gaagtcaaaa tcgtggcaat cagctcgggc agacaaatcc
    12301 aaggaatcga tacgcgagta accaataaag cccctcatac gatcgggcat attttgcaac
    12361 acggagtgat ccgagaaaaa ggaacattga cctttaatgg tatcggccac atcttgaaag
    12421 gggcaaaagg tgcagatgcc caacaagaaa gtcgtgtctt gatgctttct gataaagcac
    12481 gtggtgatgc gaatcctatt cttttgatcg atgaaaacga agtaactgct ggacatgctg
    12541 ccagtgtagg acgagttgat ccagaagaaa tgtactatct gatgagtcga ggattgcata
    12601 aagaagaagc agagcgctta gtgattcgag gattcctcgg ttctgtctta acagcaatcc
    12661 ctgtagaaca agttcggaaa gaattagtcg aagtaatcga agggaagttg aatggatgat
    12721 cgatgctaaa aagctacgca atgattttcc tatcttattt caagacgtca atgatgaacc
    12781 tttagtttat ctggataatg cagcgacgac ccaaaagcca aaacaagtac tccaggcatt
    12841 agcgcactat tacgaacacg ataacgccaa tgttcatcgc ggtgtccata cgttagcaga
    12901 acgcgcgacc catgattatg aacaagcaag agaaaaagta cgggcgttca tccatgcaaa
    12961 agaaacagca gaagtgctgt ttactcgtgg tacgacgaca agcttgaatt gggtagccag
    13021 aagcttcggc gaccgctata tcaaagcagg agacgagata gtgctctctt acatggaaca
    13081 tcattctaat gttatcccgt ggcagcagtt ggcaaaacga acaggtgctg tcttgaaata
    13141 tatcgaacta acagaagaag gcttcctgga tatggaggat gcagcgaaaa agattacgga
    13201 caaaaccaaa atcgtctcca ttgctcatgt atccaatgtc ttaggtgtca tcaatcctgt
    13261 tcaagaatta gctgaacttg tccatgaaaa cggcggggtc atcgtagtag atggtgctca
    13321 atctgccccg cacatgacca ttgatgttca agcactagac tgtgatttct ttgctttcag
    13381 cggacacaaa atgtgcggac caacaggtat cggtgtttta tatggtaaac gaaaatggtt
    13441 agaagaaatg gaacctgttg aatttggtgg cgaaatgatc gattttgtcg aattatacga
    13501 cagtacatgg aaagaactac cttggaaatt cgaagcaggg acaccaaata tcgctggcgc
    13561 tatcgcatta ggtcatgcaa tcgattattt gcaagaactc ggcatggaca atatccatcg
    13621 atatgaagaa gaactagccg cttatgtgtt gccaaaatta caagcaatcg atggattgac
    13681 tgtttatggt ccgcaagacc cgaattttcg gacaggagtc attgcgttca atttggatgg
    13741 gttacatccc catgatgtcg cgacagcttt agacatggaa ggggtagccg ttagagcagg
    13801 tcatcattgt gcgcaaccgc tattgaagta ccttgaagta tcagcgactg ctcgcgccag
    13861 cttttatttc tacaacacaa cgcaagacgc cgaccgttta gttgaagcaa tcatggcaac
    13921 aaaggagttt ttcaaacatg ggactatcta aattagacaa tttataccgt caagtgatct
    13981 tggatcattc ttcccatcca catcatcgtg gaagcttgac tgactcgaca agcaagatcg
    14041 aattgaacaa ccccacatgt ggagatgtga tcgaattgca agttgatgta aaagatggaa
    14101 tcatcaaaaa tatcgccttt gacggcagcg gctgttccat cagtacagca agtgcctcga
    14161 tgatgacaga tgccgtcatt ggaaaatcaa tagaagaagc agaacattta actgtagact
    14221 ttctacagct tgtccaagga aaagaagtca aagatcccga ccaattaggc gatgctgcta
    14281 tgcttggtgg tgtagctaaa tttcccgctc ggatcaaatg tgcgacactt gcctggaaag
    14341 cactaggaaa agcaatggaa aacgatggta ccgcagcttt ccatcattac cacaaggaag
    14401 aggagtgaga acatgggcgt accagaatta gaagaatata aattcgggtt tcacgatgat
    14461 gtcgaaccgg ttttcagtac aggagaaggc ttgacagaag aagtgatccg tgagatgtca
    14521 agaatcaaag gcgaaccaga atggatgctt gaattccgtc tgaaatctct agaaacattc
    14581 aataaaatgc caatgcaaac atgggggccc gacctttcag acatcgattt cgatgccatc
    14641 aaatattacc aaaaaccaag tgacaaaccc gctcgtgact gggaagacgt accagaaaaa
    14701 atcaaagata catttgaaaa gattggtata ccagaagctg aacgagctta tctagccggt
    14761 gcttccgcac aatatgaatc agaagtcgtg taccataata tgaaagatga attcgaaaag
    14821 ttaggaatcg tctttactga cactgactct gctttgaaag aataccctga attattcaaa
    14881 gagtactttt caaaacttgt accgccaacc gacaacaaat tagcagcgct gaattcagcc
    14941 gtatggtcag gtggcacctt tatttacgtg ccaaaaggcg tcaaagtcga tgttccatta
    15001 caaacgtact tccggatcaa tgcggaaaac acggggcaat tcgaacgtac gctgatcatt
    15061 gttgacgaag gagcaagcat ccactatgtc gaaggttgta cggcacctac ttattcaagt
    15121 aatagtctgc atgctgccat cgtagaaatc tttacaagaa aagatgcgta ttgccgttac
    15181 accacgatcc aaaactggtc agacaatgtg tacaacttag taaccaaacg agcaaaagca
    15241 tacgaaggcg caaccgttga atggatcgac ggaaacttag gtgcaaaaac aacgatgaaa
    15301 tacccaagtg tttacttaga tggaaaaggt gcacgaggca ccatgctctc catcgccttt
    15361 gcaggagcaa accaaatcca agatacgggt gcaaaaatga tccataatgc accaaataca
    15421 tctagctcta tcgtctctaa atcaatttca aaagacggcg gagaagtaaa ctatcgagga
    15481 caagtaacct ttgccaaaaa cagtgcgggt tcgatctctc atatcgaatg tgacacgatc
    15541 atcatggacg aatggtcgaa atccgatacg atcccattca atgagatcca caacagccaa
    15601 gtctctttag aacacgaagc caaagtctca aaaatctcag aagaacaact ctactatctg
    15661 atgagccgag gcctgaccga atctgaagca actgaaatga tcgtcatggg ctttgttgaa
    15721 ccattcacca aagaacttcc aatggaatat gcagtcgaac tcaaccgatt gatcagttat
    15781 gagatggaag gcagtgtagg ataaacttgt tataggagct agaatccttg gtatataagg
    15841 gttctagctt ttttattttg tctatatact agaaatgacc agcttttgac cagctctttt
    15901 actgatgagc catcatatca gcaaagtctt gacctgtttt cttaggtgca ttatttgtaa
    15961 tatgtgcata gatgtctaat gtcactttac tattttcatg ccctaatcgt tgttgaacta
    16021 ccttgacaga ttctcctgct tctaataata aactagcatg tgtatgtcta aacccatgag
    16081 gtgtaatacg aggcaagtta tattttttca aaatatatct taaccaatca ttaacagtgt
    16141 ttggaatgta tagagtgttt ttaactgttg taaaaacatg ttgctcttta gagctagtat
    16201 tgtatccaag ttttaaatac tcttcttttt gctgtaattt ccagttgttg aggatagaaa
    16261 gagtctcagt atctaaagag ataactcgtc tagaagctct tgttttcgga gattgaatta
    16321 taactttacc aaattcatct acagcaagag ttttattgac atgtagttct ttattaaacg
    16381 tgtctatgtc tttccactgt aaagcgagta cttcactctt tctcatacct gtgtatgcca
    16441 ataatctgaa gaaggcgtat tgtttcatgt taccaaaatc tttaaaagca tccagtaaat
    16501 tattaagctc ctcttttgag taaaatttac gatttttctc atactctttt tttcgtggaa
    16561 gaagtgtttt ttccatagga ttattgtcaa tatattgcat tgcaaccccg tagcgtaaaa
    16621 tttgtgcagt ctgttttctc atataatcgt aactttcata tttactgtgc cattcatcta
    16681 ccactttttg acaatatggg acagagatat tcgatagttt aagcttacca aatgctggaa
    16741 gtatttgatt atttgcgtat cttactgaga ttgcgattgt tgaagcttta acactggtac
    16801 gctgatgagt tatccattca ttatacaggt cttcaaatgt catatcaggt gctttctttt
    16861 taacaccgta taatatttga tgtctgtact cgtcataatc tttttgagct tcttgtttgc
    16921 tactaaaacc tcttctcgta gtatttattt tttcaccagt tcgtggatcg gtggcaatgt
    16981 gtcctttata catccacgcc acttgaccgt ttttcttttt gtactttgat atttttgcca
    17041 tgaaatcatc tcctcttagt ttacaaggag tacttaccac tagatggtat cacctccctt
    17101 catttttttc ttagtgtatt ttttcccaat tgatgaaatc gtttgtttta gcttgtttat
    17161 attatcaata atttcgttta cagcttcttc gggataattc atgtcttcca cttgactatg
    17221 tatcccttca tctatcattt cttctagttg ttcctctata ctgctagtga gcagaagaat
    17281 gttattgtca aattcttcta taatagcatt gatgaataat tcttctattt ttaagatatt
    17341 gaaaagacta attttttcat ttttaacttt attacaagtc ttgttagcaa taaattcttg
    17401 catctctggt tctaatttgg aatatctatc cagccatgta tctaaattag agtgtactgg
    17461 tgggaactgt tgacgaagat gctggaacag gtttttatct ggaaatgtta taccatctag
    17521 tacaatgcta tctctataaa gaataattcc caaaatatat tcttctacat tgccacaaac
    17581 taactcctct atactcatat ttcccaaatc agcaattcgg gataatcgct ctggtattgg
    17641 taaataggtt cccttttccc attcgtagat agtttttttg tcaatcaatt gaccattgtt
    17701 aatcataaga ccaaatgctg gttgtgttaa ttttttactc tttcttatag cttttatttt
    17761 tgttccgagt atcttttttc gttctaaata atttattggt ggacgcttta tcatattgac
    17821 cacacctcct aaaattagta tacctcaaaa agggggtgtt gtaaataaat tcacacaaca
    17881 tattgacacc ccttttgtat cgaggtatta tgtgtatgtc gatgaactga taatcatttt
    17941 ttatttgatt aatcggttaa taacaacaaa atacttttat tttgatcaaa taatacgaag
    18001 atgattctta gaaaatttgt tcaagtaatc acgaaaggag ggggaaatat gtctctacaa
    18061 atcattgata gcattgtttc tatacaagtt gaacaacaag tgaaagagat aattacagtg
    18121 ctaaagccta tgctagaaga cattatttct ggtgttactc tagagtatat ggactatcag
    18181 caggcaagtg aatatctagg tgtatcagta ggaacgatta gaaaatatgt ttctcaatac
    18241 gggttacctg ttataaaaat tgatacggtc attagattca aaaaatctga tattgatagt
    18301 ttcatggaac agtataaagg ttgagtaaac aaataagact aaaacatata gtaataaaga
    18361 gtttgtgttt attatctgta tgttttagtc tttaacagaa ttttataagg aggaaacaca
    18421 aatggaaaca tcaatgatta atattccaat ttatgtagat caagaaaaat tattagagaa
    18481 gccagttaca aaaaaagaaa aaactgatgt aagagatagg tgtttagata actatagaga
    18541 agttacaaga gatgagtttg tagagatact aaattcatca caatcattta ttccaagcaa
    18601 gacaaagaat aaaggcaatg acaaggagag ttttgtggaa accagagtaa ttattctgga
    18661 tgtcgataac actgttaaag atgagaaggg gaaggtagta gatttgagta aagatgatag
    18721 tagatactta agcgtagaaa aggttttatc tatcaattta gttcataatt ctgcgtttgc
    18781 gatacaaaaa agtattcggt actctgaaaa tctagaaaaa tacaagattg tctttctatt
    18841 aaaagaagca attactgact atggtaaaat ggttgctgtt tacgaatact tgaaaaagaa
    18901 catccccggg tgtgatgaca atgtaaatgc ttcgaataga atgttttttg gaggatataa
    18961 gtcagatgca gtgataataa ttaatgaaga caacatgtta gatattactg agcttccgat
    19021 tgattttacc atgacatgtt ctaaaaattg tcaaagtgat tcagggagag agtatgaact
    19081 agtcaatgaa accgattttg ttaagttgat aaaaaatgac gacaaagaag aaatgaaaca
    19141 gtggtttaaa gactgcctgt ttgattcctc cgacatgtct tttaatgaga tttatgaaag
    19201 attgttaacc attgatatga ataaattact taagtcaagt aaaaacttaa gatgtctgtt
    19261 tcacaacgat cataatccct ctgctagtat ttttaccagt aaaactgggc attccatttt
    19321 ttattgtcat tccagtaatt gtgatatcag tgaaaatttt attggagttg tgatgctaat
    19381 tttaaagaaa gacagtcggg tagaaacatt taattggcta ttagagaacc tagacttgta
    19441 tcctacacat tttcgaaaat tgaaagagga atcaaaagta ctttttgaca ctcttgaatc
    19501 aatgaaagac aaacttttca ggacaataag gaattatcta gaggaaatgc gacgtgtcta
    19561 tgatgtcttg ctttctgatg ttaatttttt tgatgatagt aaggaaagtg tgacttgtat
    19621 tttgtcgggg gaacaattag ctaaaaaaat gagttcttac tatggtaaaa cttatgacat
    19681 agataaatgt aataagttac tatcacttat gacttttata ggattgataa aaaaattaga
    19741 tgatgaagat gttcctttga agatgctcga atacctaaat aggttaaagg aagagaaagc
    19801 gttaggaaac tttaatcata agagaagcaa tgtctatcga ttagacgttt ttaatgcaac
    19861 ttctgtgatt caaaaattga atgaagatat ccttccactt ctggaaaaaa ttcattttac
    19921 atatcaatat ttttcttatg aatgggttaa gatatgtttt aacgaaaaag aggctaaaag
    19981 agtatttcct caaaattccc gatcagaact cagcaaggaa aaacaattga ttttagatga
    20041 agcacatgaa gttttacagg gcttatcgtg gcaagggaca tatctaatga cagagaaaga
    20101 acttattaac actgtttgtg aacgcctacg taatgttggg gataacagcg tgaaaaatgc
    20161 tttaataaaa aacagaggct actttgttaa acaaggattc actcttgaac gagcttctaa
    20221 ggatattaag aaactataca atgtgaaagc aagtagtagt tttttaatat atttagcgaa
    20281 aggggcaggg atagatgaaa caataaaaga attgatatta tcaggagctg ggatagttcc
    20341 tctgtatcaa tttacaagtg taacaagaga tgatggacgg agagtaagga agagaaaaga
    20401 cccaattgta ttaaactaga caggttatcc atagctctta atcttatttc atctcaatac
    20461 acccaccgtt aaagttcggt gggttattta tttttcaatc tttcaatagc tgattgcgtt
    20521 cattttcttg cctttttaat agcttcatat agtcaattgt tcgaactgca tcttcagtgc
    20581 taagagaacg atagagagcc aaaaactctt cctcataatc tacgacaaca ttgtctagaa
    20641 aatggcttac aggggttcct agggctctag aaagagctgt taagctatcg aggttaggct
    20701 ctgttacaga attttcccat cttgctactg cctgttgtgt agagaagatt ttttcagcta
    20761 attctttttg tgtccacccg agagcttttc gcttttctct aatgaccttc gcatattgtt
    20821 tctgtttcat taatacaccc ccatctcagt atagtacaac aagttgttgt atttgtaatg
    20881 gtatttgaag ttttttatat tttatgagtt gaaatacatc atattgttgt atataataaa
    20941 acaggagggg agaatcatga aaaaagtaag taatctcagc cgatacagaa aagaaaaagg
    21001 actttctcaa acggagttag ccaaaaaaat gaatgttaca cagcaatgtg taagttcgtg
    21061 gcaaacaggg agaacgattc ctaaacccta tcaaatgaaa atgctttctg agatattaag
    21121 tgtaccaata aacgagctgt tttctgatgt gtttaataaa gtaaacagtt aactattaag
    21181 caattgaatg attttaggag gagaagacat gtattgtaga aaatgtggta aagaaataac
    21241 agatgaaagt aagtattgcc agttttgcgg agcattacaa gaaacagatg agacaactgg
    21301 agcagacgaa gtaaagaaaa gtactgagca gacatttagt gaaatgaagg aacaaatcgt
    21361 acatggacaa gagacaggga agctgtattt gattattggt tgggtttcta tggtagtatc
    21421 gttagcattt attcctgttg tatttggtgc tgttgctgtt attatgggct acttatatcg
    21481 agaaacagat gagaaaatgg gtacgatttt gatgatagca ggggtagctg gagcaatctt
    21541 tggtgtactt ttagggatgt caatgtactg ataagaggga taagagcaaa ttattttgga
    21601 gataggagat aaaaagttga ataaagtaaa tatgaacaag aagtttgtca ttataggtat
    21661 cgttgtcttg gctattatag gtatcatttt ttcaaaaatg acaggtacat ctggattaga
    21721 gaagtcatct aaaccattgg tgacacagat tttacaagaa cagtacaact taaataggtc
    21781 atgtgatgat gtgacgatta ctcatgaaaa tggagataac acataccggg ctaaagctac
    21841 gttagacaat ggaagtgcta tcaatataaa tgtcgagtac tatccaaaga aagaccgtgt
    21901 atatgtagag ataccatata ctgaggtgtt aatgttaaat tgatttaaat gtattatgta
    21961 taccgtccaa acaggaactc ctaaaggtgt aagcttacta aggagttttt ttgattccct
    22021 gtaaataaaa tactaatata gatgagaaaa ataatgttat aataattgat ggaaattgtt
    22081 tttaaagagc tttaaaaatt gggttcttac attgttgatt aaatgcttta aaagaggagc
    22141 tttatgatga aaaagaatta tttaaaaaca ggtatatttt tggttatagg aactatactg
    22201 gttattcaat tatcaggttg tagaaataaa gataaagatt tctatggata ttggtcagga
    22261 actgctgaga aaattcctgt agactataat tttaaaataa ctaaagacag agtaatagaa
    22321 ctacaaaaaa atggtgaaat ggtggatttt aagtatactc taagacataa aaaatttgat
    22381 tcaactacat ttcgttcaat catgatatca aaagatgaat tagttaaagc gattccagaa
    22441 ttaaaggaaa ccacgggaat aagcaatata acgttcatgc ctattgacgg tgaaaaagat
    22501 aaattaactg tgttggtaaa tttggatgaa cacttatcaa cagccactct ttataggact
    22561 acgaaagatg agagtccaat tggtaaggta gaaaagaaaa acgatacaat atcaagacaa
    22621 actgtagata aaaaaattga tacgttcata aaaacatacg cggctatacc acctacttgg
    22681 aaacttgtaa atgaagataa gggaataacg ataaatactg atacagagat tccgactgat
    22741 gctcaatctt tatcagattt attagctaat ctaacaggag tcagtaatgc ggtgtcagag
    22801 caagtcggta aagatattcc acttaggtta cttgaaaatg gaaaaaaaga ttattctgtg
    22861 gtatttaaga acggaaaggt aactgattac aacgaaatat ttgagaaagt cattgaataa
    22921 tggtttttct atctttttat taactaccct accccgttgt tttttgaccg tgtttcgaga
    22981 ggaatcatta gaaagcatag gctaactagg ggtttctttt tcttttattt tttgggaatc
    23041 cgcttaagtg aaatgtatct gaaatgaaac ggagataaag tgattttttg ctgtaatgac
    23101 aaggttttag ctgtttcaga taccatgtaa cccaaaatag tttattgaga aaataggaga
    23161 gtatttgata ctaactagta gggaaaaatg agataaaaag taaatggaat catttcaggt
    23221 aatctgaaat aaaaaaatat acagtcctgt ggcactttac ctatgggact gtatattttt
    23281 tactctcagc gttttttgac tccgtgtctg actccgtttt attgatttta tatgttattc
    23341 agtgaccctt taacaggtca atttttatgt ttttgtcttc gtatgactca gtttgatacc
    23401 tagtgatttc catggtaata cgggatgttg aacaagctag agaagttctg caggggttaa
    23461 ttgcaaacaa ttcagataaa caaattacaa tagattattt caagagggaa attaaaaaat
    23521 cagaggaaaa atatttagat ttaaagtcgg atatcctatt agcagacgat ataggttcac
    23581 taactgtcga agaagatagc ctattctacg tctattgtgc attgacttcg taaaagaaga
    23641 cgtcttttcc aggtatacag ttcttttatc tacttcatat gaaaatttgg gtacaaacga
    23701 caaggaagtc agttttctgg tcagactatc gtacgaacat cttgttgtgg tatttacact
    23761 cagctttgat gatgagtaca agagtttttc agcgaacaag acagaacatc gaaagaggtt
    23821 tccagacgaa gttttacagg ctgggctgaa gtattatcaa gaaggactca ccattaagaa
    23881 gtctttatcg agaatataag aagatacagg tatagaagtc agtcggtcaa cattctgtga
    23941 ttacctaaac agcaaggagt aacaggtgaa cgggaaaaag agcacaggga gggctatgtt
    24001 cactggctga agaagcaaga taaacctgtt tatgacttgt tctttgaaat aaagaaagct
    24061 ttagatagtc agtcattaga gaacttcatt gatgggtatg atgaaaagtt atctaatgag
    24121 caaatgattg cgataatgaa agaggtgttt cgtcagtatg ggttatcaaa taaacgtagg
    24181 aaagaggttt ttgaccacgt taagacaata atgagctttt accacacgac cctcggctaa
    24241 atctaaagag ggcgaaaaag ggacgagtgg taaaatttaa tgggaatagc taaaagtaaa
    24301 taataataag tcaaagactg cctagtttgg tggtcttttt tcatgttcat aaaaataaaa
    24361 taggacagac gaacatcttc gctaactccc ctgtgttgca agaggcaaac tctataattc
    24421 tccagttaag ctatattttg ttctttattt tgagatagag gaaaaaacaa aaatgtgtta
    24481 aaattgaaca taagcataat tagaaattgt cgagtttttt caagtaaaaa tcttgacttg
    24541 taaggaggaa aagggcatga tgacacgcaa tcacagtact agccagcagt ctgcccaaaa
    24601 gcccatatat gaaagtgata accgattcgt agcatccgtt tcggttattt gtgttgggaa
    24661 gatgggtgat ttttagtggt tgaagatatg gtgatggttg aagaggaaca aggacgacta
    24721 atcaaaagta aaaaacgtgt ccagaagcac ggtgaggtat ttacaccgca aagaactgtc
    24781 aaagatatgt tggatttgcc aggcataaaa gaggcttgcg aggagctgca gacgactttc
    24841 ttagagcctt cagctggaga aggtgctttc ttagttgagg ttttgactag aaaaatggca
    24901 atggttgctc gtgaatataa tgagtcccta gaacagtatg aaaattactc cttactggcg
    24961 ctttcaactc tatatggcgt ggagttactc gaagacaatg ctcagacctg tgtaatgaac
    25021 atgtttcaag tattcaacga tttgtacaga gaacaatcga aaaaacatgg taccgcaatg
    25081 aaaaggaaag tccaagacag tgcaaagact ttgatttcta ggaatatcaa acagggagat
    25141 tttcttacaa aacgaacacc agatgataat ccgattattt ttagtgagtg gacacctaag
    25201 acgctaagaa aaggacagaa aaaaatcact gtaaatcgaa ctgaatattc tttggaggat
    25261 atttattcag gggtaacacg agagtttgga gaggcatact cagctctgcc tgtatttgaa
    25321 cagctcgatt tgttttcatt tgatgacgag gtcgatgaag aagtttcaaa tgatccaata
    25381 ttacgttatg tagcgatgcc gataactgag gtttataagg aagagatgga ggaaattgat
    25441 gacgacagcg ttgaaatcta aagctaaata cttcgattac ttacctaaat atggttctaa
    25501 gctagaacac ttccttggga ttcctaattt agtagatgca attaacacgt accgtgtaac
    25561 cgttaatcaa atacctaatg aagttgctat tggaactaga cgttattcgg aggtagcagc
    25621 acggaagatt gcttcaaatg tgggtattga ccagcaaagt atgaagtatg ttgatgtact
    25681 tcgcgagctt agggtcagaa ataatattac tcctacgata gctgacttat ttcataagtt
    25741 gagaaaatat ggaaatgttg cagcacatga aaatggaatt atacctgttt cagaggcggt
    25801 cgaatcttta gttactcttg ataccttgct aagagtcttt gcacgcaatc tgtctgggga
    25861 taaatcgtta aacccaaagg aagaaattac ggatgagatg tttgttatca cctataacac
    25921 ctttgaccgt aaacttattt acatccagag tgccaaggat gctgacggca catggaaaat
    25981 gtaccaagga ctggaaaaga ttggggatgc atcagtacca gagaattatg aggcagactt
    26041 tactcctaat agcgagtatt taagagagta tgcaagtaga agaataaagc agtacatgac
    26101 aacagcgggg gtaccttttg tccttcattg ggcgcaattg gctgttaata agaagaacca
    26161 atttttccgt gaccatgacg tgcatgaagt attaaagcgt tcgggctata atcctcaaac
    26221 gattggcgaa gatgacacag ggaagcctaa tgagtggttc agtgtaacag ttgacgttgc
    26281 caagaaagca atccaagcgg ttaaagatgg taaaggtagt cttgactcag aaaaagatga
    26341 ctttgacgag ttcaaaatta attttagacc agaacaaaaa gatgctattg agcagactaa
    26401 gactgtattc aaaacgaaag atgagatgct ttggaatgcc aagatgcgtt ttggtaagac
    26461 gctttcttct cttcaagtga ttaaagagag ccaatacaaa aaagttctta tcatgactca
    26521 tcgacctgtt gtaagtgatg gttggtttac ggatttcaaa aaaatcttca cagatggttc
    26581 gtacatctat ggttcaaaac aagatggaga aaagattcaa aaccttgttg ataccgaaaa
    26641 acctttcatc tattttgcaa gtattcagga cttacgcggt tctgagtggg caggtggaaa
    26701 agcaggggat aaaaactatg aattcttagc gattgactgg gattttatta ttattgatga
    26761 agctcacgaa ggaaacgaaa cggaattagc taataacgta aaggctaagt tgcggaaaga
    26821 gcataccaag gtcttagagc tttcgggtac accatttaac cttttcgata agtatgatga
    26881 ggataatatt ttcacttggg attatactat ggagcaagaa gctaaggaga aatggtcagt
    26941 agagcatccc aatgaaccta acccatacga aggtttaccg aaagtatcta tgttcacctt
    27001 tgaaatacca aataaatttg attatttcga tgaaaataag gcatttaact tccgagaatt
    27061 ctttagggtt aaggaagatg atgaaacaaa gttgcttcat gaaggtgacg tacgcaagtt
    27121 tcttgattat attactacaa acgatgaaaa gactaatttt cctttctcaa aaccagagtt
    27181 tagagaaaac ttacggcata ctttatggct gatgccgggg gttaaagagg caaatgcttt
    27241 tgaaagagtg ctcgaaacgc accctatatt caaagattac aatattgcaa acgtagtcaa
    27301 gacaggtgac agtgagcatg ctagtgattc agatttagaa ttggtgcgta aagctattgg
    27361 taatccagct aagtctaaga cgataacctt aacagttcgc aagcttacaa caggagttaa
    27421 tgttccagag tggacagggg tatttttcct ttcaaacaca gaaagtccta catcttatct
    27481 gcaggcagcg ttccgtgcac agacaccttt taaccatgca gagcttggaa ttaagaaaaa
    27541 ctgctacatc tttgattttg cacctgaccg tgctttaaaa attatgagtg gaagtgtcgg
    27601 actaactagc aagaagggaa aggttaatag ttcagagcaa aagaaaaaac tagagcgcat
    27661 gctaaatttc ttacctatcc ttggtaaaca ggggaatgtg atgaaagaat ttagcgttga
    27721 ccgaatgctt acggcactga agaaggctta tgcagaaaaa gctgtacgga ctggctttga
    27781 agacagctct ctttacaatg acaacctatt aaatttagac caagctgatc ttaccaaatt
    27841 tgaagacctt aaaaaaattg ttggctcaag taaaccaacc aaagtgaaag acttcattgt
    27901 ttcagataac ggtatgagtg aagaggagta tgaaaaagct tcgagggcag aaaagaaacc
    27961 aaaacgtcaa cgtaccaaag aggaacagga agcaatagat agggcaaaga ggcttcgaga
    28021 gcagcgaaat aaaatgattt ccattttgag gggcgtttct attcgcatac ctatgatgat
    28081 ttatgggatg gacattgata ttaaagatga cgttactatt gagatgtttc ttaatttggt
    28141 tgatgaggct tcatggaatg agttcatgcc agaggggtta agtaaagggc gattcagaga
    28201 gtttattgag tactatgatg cagacgtttt tgtggaggca ggacgcataa tccgtagacg
    28261 tgcaaagtct tatgatgagt tagatgttat tgaacgtact aggaaaatag gtgaattatt
    28321 tagcactttt aaaaatccag acaaggaaac cgtattgact ccatggcgag ttgttaatat
    28381 gcaccttggt aacactatcg gtggactttc cttctttgat gaagaatacc aaaattctac
    28441 ggagaacggt caaccaatcg tgcgatggag gaaaactgac tgtacagatg atatttttaa
    28501 ggaaaataga aagattcttg agataaactc aaaaacaggg ctatatcctt tatatgcagc
    28561 aacgagtatg tactatgttc agctccttaa acaaagcgat attaatgctg gaagggtaga
    28621 ttcagaggca atatgggaaa aagtattatc agagcaaatt tttgtcattt ctaaaactcc
    28681 aatggctaag acgataacga agaggacttt gattggttat aacgcatgga aggtaaatgt
    28741 tgaatactca agtgaattag ttacgagtat gaaacgttca atcaatgacg gtttaacgaa
    28801 tttgaaagga gtttataaaa acgtgaaatt tgatgtgata attggtaacc caccttatca
    28861 ggagaaagat ggaggttcag gagctagtgc tacaccgcta tataatctat ttgtagaaac
    28921 ctctgttaag ttatcagaac gctatgtttc gatgattact ccttcgaagt ggtttgcagg
    28981 tggtaaaggg ttagataagt accgtgactt tatgcttaac agctctagct tgaaggtgat
    29041 ggtggatata gtaaatggga aagaaatatt cccaaacacc agtattggtg gcggtgttag
    29101 ctatttcttg tgggataaga aatataatgg attgacacag tatactaatc aacatgatgg
    29161 tgtatcaaat acacaagagc gaaaaatgaa cgagtttcca gtgtttgtgc gatataatga
    29221 agccatttct gcaattcaca aaattgggga acacgctagt gttggtgact ttgttatatc
    29281 acgtaaccca tttgggcttc caacgaaaat tcgaggggaa gaagtgcagg attccagaaa
    29341 ttcaataaaa gtaatctcta gtggtggggt aggctttgtt ccactggaag atatcactaa
    29401 aggacaggat atggttggaa agtataaagt cattagtagc tcactgacta gcgaacatgc
    29461 aggtgaaccg aacaaaaatg gtatgtttaa ggtgatttct actaacagag ttattaaacc
    29521 taatgaagta gttacagatt catacctagt gctattttct gctgataccg aaaccgaagc
    29581 aattaattat ctgaagtatt tacgaacacg tttttacaga tttttattac ttcaagcagt
    29641 gacatctatt cacctatcca aagataagtt catgttcata ccagtacaag attttacctc
    29701 aggttcagac attaactgga atgtaggtat tgaagaagtt gatatgcagt tgttcaagaa
    29761 atattctttc gatgcaagtg agatattgtt tattgaccaa acaatcgtcc cgattcttca
    29821 cgaggaatat tactaagaga acaagctaac aaatgaggct tagaaccctg ttttcttgat
    29881 taattgcccc actttaaatc aagatttaac tgtctattat caacaggtca aggtaaaata
    29941 aaggatgtta gcaagtaaag agattgattt gagtctacat cgaacaaggg aataatccaa
    30001 taaaaaatga tttagaatat caaaataaca aaaaagagga ctacctgtat tagtcctctt
    30061 ttttgaccag attttgacca gtctatttta cattctaata tattcatatg agctaatttt
    30121 atgattaaat ggtaagtttt tccttgtttg ttttagttta aactagtgtg taattcaaaa
    30181 atctatatgg aagggtctgt ggggtaatac ttaaataaag gctaggaacc tgataacatc
    30241 aaggttccta gcctttttat aataaaatga agcgaaaata atttctttta aagagccgag
    30301 attatcagct atataagagt gaatttgatg caaaaaacag agccgaaaca gtcttggtgt
    30361 tcgtagctct gcttatatgt ttcgaattta agacaaagag ttggcaaaag atgttgataa
    30421 ggaagataag ataactgtgt tatataaact aggtaactaa ctgtaacaag ctaattttaa
    30481 gagattctta ttagaagacg tttaggaata taactaagaa aatgattata caggtaattg
    30541 tcatttcaat aatgttttct aattttcgcg tctttgtttt aagaaaaagg ccagaatcag
    30601 ttggaaaaaa gttcgtacga tagtgaagag gggcaaaatt tcctactaat attcccacta
    30661 acaagagata aaacggccag gttggtgtga ttcctctata aaaaaatgcc catgctaccg
    30721 aaatcccata gattaacaac tgaacaattt ttacaatgaa aaaattgttc tgccattact
    30781 caaagtctct tcctccttgt atcgtttatt tgtttcattt tatcattatg ataggcgctt
    30841 gaacaatcca ttttgtattt tattgagtac tcttggataa actaccagcg attatcatat
    30901 ttatttatgt tactgtaagc catcatataa aagtaaatga gcagatcata gaaatataaa
    30961 aaagaactaa aattgatcta aattatgtgc agcttgacta cgtaccaatc tatattactt
    31021 actagattgg tcgttaatct attcggatcg aatgagcaaa atatttttgt gaatgtccat
    31081 ccttgattat gattccaaaa agaatcattg ggaggctgtg gcgtaaatat tatactataa
    31141 gccagaaata cctatcattc tgaacttttt tatttaggaa ctttcatctc aaggcttttt
    31201 caattaattt gtacccctgt tttttggata agatcatgtg cattgatttt ttctatctct
    31261 acgttcatct cctacttaat gcctatctgg ctcctgaggg cttcttttta aggcgtcgtc
    31321 atagtcttgg ctgaggattt cttggtaatc tgagggaatg gcttcccaag tgagcaggcg
    31381 aacgttcatg acgtgttttc ctttgtgttt gattacagca tggtttttct ctttttctac
    31441 ctctccagcg tgaaaagaca gccatgtacc atggccaaag atatcattac atacccaacg
    31501 ttcgatggaa ttgtccacgt atcctacagg gagtgtggta tagccgattt gtggtttcaa
    31561 aaaaggattg aatcgatcga tcgtttcatt tttgtattga taattgataa gaaaaagata
    31621 gaccaaacaa aagacgagca gaaagaaaga tagtgtcttt ttgagtgaga agggttgttt
    31681 tgatgaataa gatttcttgt taacaagagg ttcatctggc aatgttggtt ctattgattc
    31741 ggtagctgat tcaatagaag gaaaatcaat cggcagacct aaagtatgat gtaaaagtga
    31801 cagcatttca aagtctggca ttgtacgaga attttcccaa ctagaaatcg ttttatcgga
    31861 aacaccaatt ttttcgccta attctttttg cgtaagctta caatttctgc ggtaagttcg
    31921 tattttttct ccggtgttca tcttcttctc ctttcgattc tacagtatat agatttattc
    31981 tacatgacct atacacttga tagatacgtt tttttgatga aaaacggtat gattttatca
    32041 aagaatcatt taagtaaggg agagtggtga taatcaaaaa aaagttcaca gttttactca
    32101 caatcatagt gaccggtatc atgagtggtt ttgccttggt tagtataaat aaacaggtac
    32161 tctatcggac aaatgaattt ttccatcaaa cagatactta tactccgatt cgattgccac
    32221 aacattttat tgggcaagaa gaatatgagc agctaatcat ggtatttgaa aatgtctcat
    32281 cagaaactga gctttcttat atgaaaaaaa cagtaaatga atccaatgaa gtagatacat
    32341 cttggaactt caagatacag ccaaagcttg aaatgacatt gtattatcaa ggggatgtca
    32401 aatcttctca cgagaaggta ccctattcta atacctcctt tcgcgtaacg tccattgaag
    32461 aatcgatcaa aataaaagat tttgaaggtg aatttttctt gatgacgaga gaaaaagaag
    32521 cctatgaacg ggtcatttca ctattcactg atcgattcaa tcaagcattt cacactgatt
    32581 atgccactaa tatttttgaa gactttgaaa atagctattc gtattcggtt atttcaaata
    32641 cagacgtata taattatcga gtgtatttaa ctattggatt gattctttta ttccttttgt
    32701 tatcatcctt tttcttattg atgaataaag aaatcagttt attgttgaat aatgactttt
    32761 cattacatca agtattgtgg tgtttattgg ggaaaaagaa aatcattatt acattcataa
    32821 ttgcaggaat cattggtggt tttattttta tgtattataa ggagcaattt ctttatttgt
    32881 tccagatgta cgttttcttg ttcagcggaa tatatggtat ctctttgatt tctcttttat
    32941 tagttgaaaa aatcgcttcg ttaagagaag cgttcaacta tatccaatac attcttttta
    33001 catttggatt gttgttttct cttcttttga ccgttgccaa tgtcgaatta gcaactatcg
    33061 ttttttcttc ttcacagtta gctgtttccc atgaaccacc aaaagaaatc gctggtgagg
    33121 actatcatgt attttatcca gtaaccatcg ggaaaaacca cgtggatttt atttattcca
    33181 atcgttttgc atcagcagca gatcaggaat tatatgaaac tttgaataaa aacggaagta
    33241 tattagtcaa tgtatcagat tacttgaatg aagaaaatga acagtttggc agagggataa
    33301 aaataaatct gaattatctt aagaaatttc ctttgattga tgtctctgga aggttgatcc
    33361 aaataaccga aaaagaaacg caccctgtta tattgatccc tgaacgatat agacatacag
    33421 atttaaaaaa tgacctggcg caaataacag aatattatca agaaatcagt gaaaaagaac
    33481 cgaaatttct atttataaaa aacaatcaac ccatttatac atttattcct tctatcccct
    33541 ggatcgaaca ttatccggtt gttgaaatac tgacattgaa aaacagtatg tatttggaaa
    33601 gaaatattct cagcggagaa atctatccac cgttaaagat caagataggc tctttgtcga
    33661 aagaaaggtt atttgagctg attgaagaaa gtcagttacg tgataacttg cagttatcat
    33721 ttccgtatac tcagactgaa gagatagctg tcaaagtgtt aagcagatca tttcattact
    33781 tgatacagat atttttactc actttctttt ctttcttctt gttgagctat gtcatgttat
    33841 gcatatattt tgtctacaat tgtcggaaaa tcgctatctt tcgttcaagt ggttattcgc
    33901 tctttgaaac gtataaagat ttcttcatga tgaacctcat caaatgggga acgacaagtg
    33961 taatcttcct ttttcttata gaaagagagc ctaaatatct ttttaatatt tttttcttta
    34021 gcttcattga ttttattctt tcagttgttt ttattttgtc tacagaaaag aaaagtcagt
    34081 tattgctgat gaatggaggt taacaattgg agccgttgat agtgataaaa ggtgcgaaaa
    34141 aaatcattcg aaacaaaacg attcttcatt tggatcgttt cactgcggat gctggggatc
    34201 ttgtgactgt tgttggagaa agtggagcag gtaaaagtac gttattgaat atattaggat
    34261 tgaatgatca gttcagttca ggacaattct atttgttcga tcaagagacg aaacaattaa
    34321 ctgggagaga gaagcgcttg ataaaaagaa ataccatatc ttttcttttt caagattttg
    34381 ggttgattga atatgaaaca atcgatttta atttagatat tggattgaag ttttcgaatt
    34441 taaatgtttc agataagcga acagcaaagt atgaggcatt gaaaaaagta aatataaaca
    34501 agaagctaag tacgcctatc tacacattat ctggtggtga gaagcaaaga atcgcctgtg
    34561 cgagagtctt attgaagaat agcaaaatca ttttagccga tgaaccgact gggtcattgg
    34621 ataaaagaaa taaggataaa gtagttgaaa tcttatcgca acaagcttcc caaggtacgt
    34681 tagttatcgt agtcacgcat gatccatatc tgaccaaaat aggaaacaag aagatcatgc
    34741 tttaaaaatc aaaaaggaaa ggatgtcgtt ttatgaaaaa agcagttatt atttgtgcac
    34801 tagggatagg ttttgttgga ggaaacgcta tgtcatctga agtggaagca aattcagttc
    34861 acggtgaaat ctattacaaa tctttaaagc caggagagat tcattttgat gctaaaggta
    34921 atattattaa gtcaaattta ccagtagacc gggaaatttc tagaacagca attaatcata
    34981 gctctggaag atgggtttat tatagtgata caacttgtac gagaaaaaca ggtcattcta
    35041 accactatag tcgtgtctat aatcgtcacg gtgcaaaagc gaaagttgga aactctattc
    35101 gatcagcaaa tgcaacaaaa ggagtatggg cctatgcaag tgcgacagga aatagaactg
    35161 acacattctc atgttggtac aatccaaccg gttggtatta agtatccaaa agtttatata
    35221 aaatagaaaa aacatataat gaaacagcgt taaaagttat ttttggtagt tttaatatat
    35281 tcatttttag ttgtataaaa atatatcata ataaaaacaa caaaaaaatg tctggaaaat
    35341 cgaacataaa agtgtctgat ttgaatatcc cagcagcgga agaagaaaaa caaaatcgat
    35401 aacatttgtt ctaagaatta gttacgttaa atacggaacg caagatagac ttgaaaaacg
    35461 gtaacaaaag aagtagtata ttaaggtgtg atgtgctact tgacatttat tctgctgagc
    35521 gaactttctg gattgtgtag ccttatatct attcaggacg tatcgagcag attagtaaag
    35581 gtgttcttga tgattttcat cttgaacacc tttgttttta gcaattcgca aaaaacgaaa
    35641 agtaggagaa ttgataaatg aaaaaaagat ttttagcact tgccatcgta ctaggcactg
    35701 gcttattgtc aggctgtacg aatgccggtg aaaaaacagc cgttagttat aaaggcggta
    35761 caatcagcga acaagaagta atggatagct tgaaaaaaat gcaaggagca gattccgctg
    35821 tgcaacagtt gatcgtttat caagtatttg aagataaata tggagatgac gtatcaacca
    35881 aagaaatcga ttctcaatat gatcaaacaa agaaacaatt gggtgattca tttgattcac
    35941 aattgaaatc tgcaggttac acagaacaaa cattcaaaga cagtatcaaa caaagtctag
    36001 cctttcaaga aggtctaaag aaacatatca aattgaccga tgaagattta aaaacggctt
    36061 gggaatcttt ccatccagaa gtggaagctc aaattatcca agtagcaagt gaagatgatg
    36121 caaaagatgt gaagaaagct gctgataagg gagacgattt ctctaaatta gccaaagaca
    36181 agtcaactga tactacgaca aaagaagatg gcggaaaagt gaaatttgat tccactacta
    36241 caacggttcc ggcagaagtc aaagaagcag cctttaagtt gaaagatggt caagtttctg
    36301 atgtgatcac ttctaccaat gcttcaactt atactacgga atattatgtg gttaaaatgg
    36361 tgaaaaacca aaacaaaggc aacgacatgg ataaatacaa aaaagaattg aaagaaattg
    36421 caacagacac aaaattaagt gacagtacct tccagaataa agtaattggc gaagtattga
    36481 aagacgctaa tgtaaaaatc aaagacaaag actttgaaaa tgttttgagt acattcactt
    36541 cagattctag tacagcaagt agtaaataag cggtataaat aaaaaatatg aactatttaa
    36601 atcaataaaa ctgttcatct aaatcttttt attagaacta aatcaacagt agtttaatta
    36661 ctacttgatt tagttctttt tattttaaaa atttttttta cttagaatcc agcgacccta
    36721 gatatttttc tgtataatct taaataaaga aaacaatatc aaaaaatgca cgtagaagta
    36781 gataaatgga gtggttttgc aaatttcttt tatttctaga agttattcac gtatacggat
    36841 ttgtttttct cacaaataaa aaggcaggaa gtacaatgga tcatttgtat ataaaatata
    36901 ttcatcaatt ttccgttttg gtgttaggca cactaattat agcggggatt gtcgcattta
    36961 ttattcaagg ccgtgacata ttaacagtac atcaagagtt tttcagttat gcatttggta
    37021 ttcctctgat cgctataagg tctgataaca aaaagtggaa gaaacgctat tacattctct
    37081 tgctattttt gtgtttttat ctgccaccta agatttttac tttattaggt atacaatgcc
    37141 tatcattttc ttttatttcc tatatcattg ttttaatttt cctcagtttc atagtatgga
    37201 tgttttatct tgtcaaaaaa taaatgaatg tttcatgaac agtacttcat cacagcctaa
    37261 tttttttctt tatgctatcg ttatattaaa gaaatcaatc agaagggaaa gaaagtgatg
    37321 aaaaaagttt tattagtggt aaaccccagt tcaggcggtg aacaagcaaa ggaatttgag
    37381 caattagcga tagcaaaatt ggaatcggtg tttgatgaag tggtcgtctt gcatacaaaa
    37441 aaagcagggg atgcaaaaaa ctttactcgc gaagcggcta cggaagggta tcatagtgtg
    37501 tttgtcatgg gcggagatgg aacagtcaac gaaggaatca gtggaatcgc tgaacaagaa
    37561 catcggccaa atttcggatt tttcccattg ggtacggtga atgacttggc tcgagcatta
    37621 gggataccgc tagaacctga ggaagcgatc aatcattttt cgattgaatc agtcaagcca
    37681 ttggatattg gaaaaataaa tgacgactat tttatgaatg tcgtcgcaat tggctctatc
    37741 cctgaatcaa tcaatgatgt agatgcggag aagaagacga aatttggaaa actagcttat
    37801 ttcatgtcag gaatcaaaca gttagcttcc acacaatcct actcgtttca cgtagaagtt
    37861 gatggaaaga aggaagaaat tgagagcagt accttgctga taggactaac taactcagtc
    37921 ggcggttttg aaacattact tccaaatgca aaagtggatg atggtaagct ccatttggtt
    37981 tatttaaaag attcttcttt gatcgatacg cttaaaacat tgccagacct attaaaagga
    38041 gtagatgaat ctacgaaaaa tctagcctac cttacttgtg agcaattagt tgtgtcatta
    38101 gctgatgagg aagaattgac gacgaatgtt gatggagatg aaggggataa attacctgtg
    38161 acaatcaaag tattgccctc acatttacag gtttattgtt aaaatggagg ttgtgaccga
    38221 ggagttggcg ggagaacacc gcttgttcgg gataagggac tgtgacaaga cttttgtcac
    38281 agcctttttt ttgtacaaaa aagaaattta cacctaatag aaaaattttt ccataaaaat
    38341 acatatttta aatatgaaag tacaattgga aatagattaa aacgataaaa taaaattgtc
    38401 aaaacgtcag agaggatggt ggagaatgaa tcaatgtgta aaaaagctga ttgcgtcgat
    38461 tttgtttgtc ttccctctct tgatggtgac atccgttttt gccgatgtag agaaaacaaa
    38521 cgaatcaacg caatcagaga atcaaagttt tgacaagact actttttcag aagaatcgat
    38581 tacttctgaa actacagaat ctcaaagtga ggcttctact aataaaaggc aagaagaaaa
    38641 taagacaagt gagacctcag aagtagctga acaaacgtct gatagcagtg aagcggcact
    38701 ggcaagagct gtttcagcgg atgggtacag cgaagctgcc acaacagaag aactggcgca
    38761 gcttctcgca gacgaatcag taactaagat ccgactgatt cagcctttga ctttagacag
    38821 ggaattagag atcaaacgag atatcgttat tgattttggt ggattcgctc acaatttcgg
    38881 cacacaccat atttatatca atgagatacc tcagtcgatc gagttccaga attttaaagg
    38941 aacagctgca catccaggtg gattgacacc aaatatcgat ggaaatgcca ttatcattgc
    39001 ttatatgacc gatttttggg gaagcaaata tcattttacg ggagaaataa aatttaccgg
    39061 gacacttgat ttgtatgatg ggtccaaatt aggactgatt tacgctcctc gtgcaactgt
    39121 cacattagat ggtgtttccg gtgtgttgga tgtccaacca gtgaaggaag gactgaatgc
    39181 cgctccgggt aaagcctatt tttgtagaag ctatcaattg aatgtgatca atggtagtca
    39241 actttatgga ccgtatctag ggaaattcta cggttttcta gattcaggag atgagactgg
    39301 tagtggaaaa acagcgccag gaatccatat cttaagcggt tcaaaggtct ctcttgatta
    39361 tgatcgggca gatggcgtta gcgatgaagg agaggcagtc gatacgctac ctggtaatgt
    39421 catgtttgaa gtcagtggtt cgggaagcga attttcggta aatacaaaga tcaatattac
    39481 caatgacaac aatcgcggaa tcatccaaat gagaggttca ggatcgaaag tcactgtatc
    39541 gaatggtggg aaaatcacca tcaatacagc aactacgggc ggatttcgct tgcaaggaga
    39601 ttctagtcaa atccatgtat caagtggtgg acaaatctcg gtcaaaatgg ctggagatga
    39661 cgatcaaccc gggaacaatg ggatgcgttt tgtaggaaaa ggcctttctt tgatcgtaga
    39721 aggagccgga tcagttatcg acatcgataa gcagagtggg cgttccagcg cagttcgttt
    39781 tgagaatggt acgcaaaagc tgacagtaac caatggaggc tcattgaggg taagaaatac
    39841 aggtgatggc aaatcttacg tgaacagact caatcaagga aatcaagcga tccaatttta
    39901 tgacgcttct ggttttctag aaagtccagg ttcagctgat tttacagtca ctggagaaaa
    39961 atcaaatatc gatatacgcg cagattccgg agcaactgta gatacaactg gagatattga
    40021 tttaaatttt acggcaggtg aaaaaactta tttagtcatg gtcgggaaaa caggggaaga
    40081 taagaccggc atcatcagtg gggatgtgtt gaatgtggac ttagaatctc ctacctattt
    40141 tgatttccaa aacaaacgga ttggaagcga gaccaatggc ataggcggct gggtattcca
    40201 aggaaatgga gattcttctt taaagatcgc ccattcagaa atcgctttat ggcgaaaaac
    40261 aggcgcaaca ttcgataact ttgaaaaaga cccggattat ttttctgata tgacagactt
    40321 atcgatcaat gggaccgact taggcaattt cgtatcaagc cctagtgcag gtttaacaaa
    40381 tgaatttgct cagacaggtg ccggaatgaa aaattataat cgaatcagtg ccaataatca
    40441 gctcccgatg attgaatcct taagagtgcc aacgaatgca gataaaaaaa tctatgggca
    40501 tgtcgttgtt cccgaaggtg tcgaggcaaa gccaagagat gcttggacag gcgaagtaga
    40561 agtgacttta cgtattactt acgcagatac gacgaaatca tctgtagaaa ttactgctct
    40621 cacgcaagga caaacagatg aaaatgaagg ggcaggatat aacccatggg gagaaggcga
    40681 acaaggcggc ttgttcgaag ttcaagtacc caatgatgag agattaaaaa cggaggatca
    40741 agtgcaagtt gttgctgcta aaaaagtaag aggtggccaa gaagtgacag aactggactc
    40801 tgccaaaacg acagtcgatg tgattcctcc tgaacctgct aatttaagta ccacattgat
    40861 caatgcagct tctcgcacga tcacaggtac aggtgaagca ggagccttgg tttcattgaa
    40921 aaaaaatcaa gctgttttgt cagaaacaac tattgatgat acaggggaat ttgttctttc
    40981 tatcccagaa aatcaacttt ttgcaggaga tgtattagaa attgtattaa acgaccaagc
    41041 aggagaagct actgctaagg gtgtgcagaa caagccaagt accaacgatg aaattgggaa
    41101 tcacaatcca agtgatacgc cagttgttta tcatgatgcc ccgccttttg cacctgctac
    41161 gaagatcgta gtagaaggtg gtctctcatt tcttgcccct tccaaactcg attttggtca
    41221 gatcaaagca actggtttga cacaagaagc atttggccaa atggatatac aggaaaaatt
    41281 atggatttat gatcagcgag aaacgaaaaa tccgtggatc ttaacgataa aattatctca
    41341 gcctttcaca aatgatgcag gattttctat gcaggatgtc ctatatttca agaaaggaga
    41401 ggagtatcaa ttagtgaatg aagaagaact ggaaattgtc agaggacaaa attcaacgaa
    41461 tgtgcaagca gattattcag aatatttaaa taacggtcgg gcgtttaaac ttgtcttaac
    41521 caaagaaaat cagatagctg gtaattactc agcagagata acatggacat tagcagatgc
    41581 gccgacagaa taaagatcaa ggaggatgat tgatgaatcg aatatggaat aaaagtcatc
    41641 gaaacaactg ctctttactt atgatccttc tccttggatt catcctttgg cagacacctg
    41701 tccatgcctc cgaattcaat tttgcggtag attttgaatt accggctaat cagattgata
    41761 agaacaaaac atatataaat gtaaggatgg agcctgggaa aacacaggaa atcccctaca
    41821 cggtctttaa ccgaacagat aaatcagtaa cagttgagac attgatccac tccgctacga
    41881 cgaattcaaa cggtgtgatc gaatatggag aatcaaaaag taaatttgat gaaacattaa
    41941 gttatgatat gaaaaactta gcaaaaacag tgggagaaat aactgttcct cctcaaagtg
    42001 cggtcactga gacactttca ctgaaagcgc cagaaaaaga gctggctggt gtggtcgcag
    42061 gagggatcac gtttcaagaa aaaaaagaga acgtttctaa caaaagtaca gttggtgtcg
    42121 tcaatcagtt ttctcaagtg aaagcaatct tgatttgaaa tagcgaaaaa gagtcttccc
    42181 cagatttgaa attaaaaaaa gcttatgcgg atcaaagcga tggaagaaat gtgattaagg
    42241 cgaatcttca aaatccaaat gcttcttata tgttcggctt gactacatcg gttgaaatct
    42301 acaaaaaaga aacaaaagag ccttaccttt caataaaaaa agaaaaaata gatgtagcac
    42361 ccaatacaaa ttttgattta cttgtcccat tagaaggaaa aaaattagct ccgggacatt
    42421 atcaagcggt tgtgaagggt gcttggaaag aaaaacgctg gaatctccat accgattttg
    42481 aaataactga tgatgcagcg gaccaattga atgaaaagga tattgattta aaaaatcagc
    42541 cagaaacatt tgactggcga tggctgatac ttgttggagt cattcttatt ggcttatttg
    42601 ctggattatt tattt
//
LOCUS       DAKCAA010000019        41205 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000019 DAKCAA010000000
VERSION     DAKCAA010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 41205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.019"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(26..328)
                     /locus_tag="OUE31_001131"
     CDS             complement(26..328)
                     /locus_tag="OUE31_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0222152.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(353..2446)
                     /locus_tag="OUE31_001132"
     CDS             complement(353..2446)
                     /locus_tag="OUE31_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCU0222153.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2935..3699)
                     /locus_tag="OUE31_001133"
     CDS             complement(2935..3699)
                     /locus_tag="OUE31_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HCU0222154.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="OUE31_001134"
     CDS             complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="OUE31_001134"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HCU0222155.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4704..5780)
                     /locus_tag="OUE31_001135"
     CDS             complement(4704..5780)
                     /locus_tag="OUE31_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HCU0222156.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5804..6397)
                     /locus_tag="OUE31_001136"
     CDS             complement(5804..6397)
                     /locus_tag="OUE31_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HCU0222157.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="OUE31_001137"
     CDS             complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="OUE31_001137"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HCU0222158.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8067..8366)
                     /locus_tag="OUE31_001138"
     CDS             complement(8067..8366)
                     /locus_tag="OUE31_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HCU0222159.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="OUE31_001139"
     CDS             complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="OUE31_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HCU0222160.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(10121..11032)
                     /locus_tag="OUE31_001140"
     CDS             complement(10121..11032)
                     /locus_tag="OUE31_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCU0222161.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11152..12009
                     /locus_tag="OUE31_001141"
     CDS             11152..12009
                     /locus_tag="OUE31_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCU0222162.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12196..12558)
                     /locus_tag="OUE31_001142"
     CDS             complement(12196..12558)
                     /locus_tag="OUE31_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HCU0222163.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            12904..14343
                     /locus_tag="OUE31_001143"
     CDS             12904..14343
                     /locus_tag="OUE31_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222164.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(14350..16902)
                     /locus_tag="OUE31_001144"
     CDS             complement(14350..16902)
                     /locus_tag="OUE31_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HCU0222165.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(17016..18347)
                     /locus_tag="OUE31_001145"
     CDS             complement(17016..18347)
                     /locus_tag="OUE31_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0222166.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(18313..19791)
                     /locus_tag="OUE31_001146"
     CDS             complement(18313..19791)
                     /locus_tag="OUE31_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0222167.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="OUE31_001147"
     CDS             complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="OUE31_001147"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCU0222168.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            22401..23828
                     /locus_tag="OUE31_001148"
     CDS             22401..23828
                     /locus_tag="OUE31_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222169.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLHEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(23920..24285)
                     /locus_tag="OUE31_001149"
     CDS             complement(23920..24285)
                     /locus_tag="OUE31_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCU0222170.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(24282..24647)
                     /locus_tag="OUE31_001150"
     CDS             complement(24282..24647)
                     /locus_tag="OUE31_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCU0222171.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(24839..25087)
                     /locus_tag="OUE31_001151"
     CDS             complement(24839..25087)
                     /locus_tag="OUE31_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222172.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            25086..25214
                     /locus_tag="OUE31_001152"
     CDS             25086..25214
                     /locus_tag="OUE31_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HCU0222173.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            25271..26965
                     /locus_tag="OUE31_001153"
     CDS             25271..26965
                     /locus_tag="OUE31_001153"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HCU0222174.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            26969..27088
                     /locus_tag="OUE31_001154"
                     /pseudo
     CDS             26969..27088
                     /locus_tag="OUE31_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            27739..28872
                     /locus_tag="OUE31_001155"
     CDS             27739..28872
                     /locus_tag="OUE31_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HCU0222175.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            28903..29223
                     /locus_tag="OUE31_001156"
     CDS             28903..29223
                     /locus_tag="OUE31_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HCU0222176.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(29252..29716)
                     /locus_tag="OUE31_001157"
     CDS             complement(29252..29716)
                     /locus_tag="OUE31_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0222177.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(29847..31100)
                     /locus_tag="OUE31_001158"
     CDS             complement(29847..31100)
                     /locus_tag="OUE31_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCU0222178.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(31129..31446)
                     /locus_tag="OUE31_001159"
     CDS             complement(31129..31446)
                     /locus_tag="OUE31_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCU0222179.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(31472..31792)
                     /locus_tag="OUE31_001160"
     CDS             complement(31472..31792)
                     /locus_tag="OUE31_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0222180.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(32256..33671)
                     /locus_tag="OUE31_001161"
     CDS             complement(32256..33671)
                     /locus_tag="OUE31_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCU0222181.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(33688..35004)
                     /locus_tag="OUE31_001162"
     CDS             complement(33688..35004)
                     /locus_tag="OUE31_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCU0222182.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(35154..35852)
                     /locus_tag="OUE31_001163"
     CDS             complement(35154..35852)
                     /locus_tag="OUE31_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCU0222183.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(36141..37097)
                     /locus_tag="OUE31_001164"
     CDS             complement(36141..37097)
                     /locus_tag="OUE31_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCU0222184.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(37210..38043)
                     /gene="msrA"
                     /locus_tag="OUE31_001165"
     CDS             complement(37210..38043)
                     /gene="msrA"
                     /locus_tag="OUE31_001165"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCU0222185.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(38218..39852)
                     /locus_tag="OUE31_001166"
     CDS             complement(38218..39852)
                     /locus_tag="OUE31_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222186.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(39839..41173)
                     /locus_tag="OUE31_001167"
     CDS             complement(39839..41173)
                     /locus_tag="OUE31_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222187.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
BASE COUNT        12501 a         8475 c         6958 g        13271 t
ORIGIN      
        1 tttttaccct cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga
       61 ttttttcttc aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag
      121 gatcaactgc gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg
      181 gtttcatgga aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt
      241 tgttcaaaac atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc
      301 atacgaataa aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct
      361 caactactga aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat
      421 ccaacttctc ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt
      481 aggagtctac tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga
      541 aatcgattgg ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg
      601 gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca
      661 ctgcacgaat catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc
      721 tagcagctag ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc
      781 tgtccgtcaa aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt
      841 ttgtttcgaa taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt
      901 ctttcatgac atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta
      961 accgctgtag ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag
     1021 ttaaaatcgg atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga
     1081 aaaccagatt gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag
     1141 taatctcgat ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca
     1201 tcccatggtt acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac
     1261 tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac
     1321 caattacttc ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat
     1381 ttgttcggat gttttctttc aatggattca tgacttggat atgattcttg attcttacaa
     1441 tcagtgcagc catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag
     1501 gtacgtgtgt ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta
     1561 cccactcgat tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat
     1621 aatttctttc tacttgcggg acattgtcca attgaaattc ctcgatcatg tggtcaataa
     1681 atgcagaaaa gctactgtct tttatttctg tatttttcca attaatggca gagataaatt
     1741 catgtttcct gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa
     1801 tatcatcttc ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca
     1861 ccaaaggaaa ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca
     1921 taaagaagtc ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag
     1981 atcgttctga acctttataa accagtcctt gctttccata actgacgatc tctatcccat
     2041 aactgaccag tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt
     2101 gaaattcttc ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa
     2161 ctagatcaaa aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag
     2221 tttctaatcg agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg
     2281 tacggatctc cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac
     2341 ggatcgtccg ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt
     2401 gggctgtcat gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct
     2461 tctgatttca agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga
     2521 agtggaaaga aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca
     2581 acgaaaaaga catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt
     2641 gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat
     2701 ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga
     2761 ggttgtgaca gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc
     2821 atattttaca aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag
     2881 aaaaaggagc tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc
     2941 cagcataatc ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa
     3001 ataccatatc tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc
     3061 ttttcgatcg actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc
     3121 gtggatctgt cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac
     3181 accgtctgct ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata
     3241 acagcttctg gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat
     3301 cttttggatt tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa
     3361 tatctccgct ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac
     3421 ccctcctact gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc
     3481 tgtacctgga ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact
     3541 gcccccatat gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc
     3601 tccaccatga ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc
     3661 cactaacaaa atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta
     3721 ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat
     3781 aaactgtttt tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat
     3841 gtgtcggcag tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct
     3901 gcgcttcctc caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga
     3961 cgatttggta aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt
     4021 ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac
     4081 atatgcattt gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca
     4141 agcctgatat gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt
     4201 tgcttcaccc tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca
     4261 gcaagcttgc tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt
     4321 ttttgtgcaa tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg
     4381 atgccatttg tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt
     4441 tctcttaact cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa
     4501 ggagttagcg tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc
     4561 gcatccagtg catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct
     4621 tcctctacca acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg
     4681 acactcactc cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg
     4741 atatgaagta accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga
     4801 atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg
     4861 aaaacaaata cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat
     4921 ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg
     4981 atgactaaac tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag
     5041 tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt
     5101 aagaaaagat aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg
     5161 gctaccccat aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga
     5221 taaggcccag tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt
     5281 gaaccaatca atactggcca tacatatttt ttattagcaa atactttgta accgagccaa
     5341 acaaaaaacg gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc
     5401 gctccatcac ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt
     5461 tgttggactg ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact
     5521 agttcaaaaa acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc
     5581 atattataaa caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag
     5641 gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc
     5701 gtttgcatca taacagccgt tacagctgat actttctgga agtcacttac gttgattttg
     5761 atttttttgt tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg
     5821 ttaatttagg tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact
     5881 cttttagtga aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag
     5941 caggatgcga ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca
     6001 aatcaaaatc actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc
     6061 tgccgccgat tccccattta catcctgata atatgtttct agcagcatga aattgctgat
     6121 aaacaggata atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg
     6181 gatgaatgac ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg
     6241 caggtccacg taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg
     6301 ttccgaacat cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat
     6361 gtttatcaaa aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt
     6421 ccattttggc acggacttta tttgtttcga cacgtccgaa tgttttggct gtttcgtttg
     6481 tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga
     6541 ttgcttcgat gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta
     6601 ggaaatgata gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa
     6661 ctttttcagc agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt
     6721 ctttagacat cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt
     6781 gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg
     6841 gatgtccagc ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga
     6901 taccgatcaa ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga
     6961 ttggccgttt cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca
     7021 tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag
     7081 gatcaggtac gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat
     7141 acacagtact aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt
     7201 aaccaacact tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt
     7261 ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat
     7321 ctaaagaatc aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc
     7381 gttcgtccat tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt
     7441 catcaatgat ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt
     7501 tgtcactaga atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca
     7561 aaccgactct cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca
     7621 taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta
     7681 gagcaatgat tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca
     7741 aacgaacacc acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt
     7801 cttctaacac atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc
     7861 caccttggaa ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac
     7921 ggctgacaac gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg
     7981 cgatgatttg atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc
     8041 gttctctggc gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc
     8101 gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct
     8161 gaaattggat aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca
     8221 tcgcttcctg tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt
     8281 tccaaatctc ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt
     8341 ggatatttat aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca
     8401 cgttctgctt attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc
     8461 gccaatttta tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt
     8521 cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga
     8581 tgcctagatc ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt
     8641 tcgtgctagt cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt
     8701 cttcttttgt ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag
     8761 tatcttcgct ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta
     8821 gtgcatctaa ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt
     8881 gaacaactaa tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg
     8941 ctggtgtaga atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac
     9001 cagataaacg tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg
     9061 aaccgataaa catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc
     9121 gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca
     9181 taccaacttc gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa
     9241 tcatcgttgg atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg
     9301 attcaccata agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat
     9361 tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa
     9421 tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt
     9481 tatctgcttt cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat
     9541 cgacaacttc gttaacttga acgatcacga taccatcttt gaaagctgca gcttcgatga
     9601 ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat
     9661 ctgcagctac taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca
     9721 aataagtatg gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca
     9781 agctttgtgc accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat
     9841 tcaaatgttc tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg
     9901 catctacttt ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta
     9961 atacaacttt gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt
    10021 ctacatactt gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc
    10081 gtttagaagc ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata
    10141 gaaacgtggc gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta
    10201 caccaaattt tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca
    10261 gatccattcc taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta
    10321 ggttttccaa caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat
    10381 tttttatata caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt
    10441 tcttgaccgt atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg
    10501 ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc
    10561 cagataacgt atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat
    10621 caaatgtttt tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca
    10681 ttgcataacc gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg
    10741 ctgcattctc aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat
    10801 gtcctgctgc aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg
    10861 cttttgtcag taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa
    10921 ctaaccgata ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta
    10981 acatccctaa cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg
    11041 cctcctcagc acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat
    11101 gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg
    11161 cttcatctgc agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa
    11221 gaattattta tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta
    11281 ggtgtccctt tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa
    11341 ttttatccat atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct
    11401 tcggtcaatg agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct
    11461 attccgaact tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg
    11521 caacatcatt taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag
    11581 cctggcatga ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa
    11641 catcctcttg ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg
    11701 atgctgtcaa agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt
    11761 atcgaattga cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag
    11821 caaggattag ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct
    11881 ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc
    11941 ttcacagaag atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta
    12001 ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa
    12061 cggtgttcca gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc
    12121 aattttcgta aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc
    12181 tattgtccta gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc
    12241 atctagcttt tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata
    12301 ggctggaaaa tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa
    12361 atcaagaata ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac
    12421 agacatcagg accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg
    12481 aaatttttta aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag
    12541 ttcttttttc gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat
    12601 accacgtaag aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt
    12661 cttttttatc aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat
    12721 taaaatgttt attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag
    12781 ttcatgatga aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa
    12841 tcagttgaaa cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga
    12901 ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct
    12961 ttagtagaac aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata
    13021 gggacaaccg aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa
    13081 ggctgggaca tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta
    13141 acaaatgacc tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat
    13201 ctgcttttta caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat
    13261 gggacattga aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag
    13321 atcgatttga cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt
    13381 tatcatcgat tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc
    13441 catgaatccc attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa
    13501 acagaagaga ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat
    13561 tgccgattag attcttctat ccataccaac agcacactct cctccctgta tgactctgca
    13621 ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct
    13681 tctttctgct ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc
    13741 tgcctgcatc attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca
    13801 gagctgtctc ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata
    13861 ttaaaatatc atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt
    13921 ttagaaacat atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac
    13981 gatctaaaaa aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta
    14041 ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc
    14101 caaggagaac cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa
    14161 cgtgtctgct tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca
    14221 gatatcttga tttccaattt ccctctagat tctctagata tccctattgt atacatttct
    14281 tctattccaa cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aactttttta
    14341 tagtaacggc tagcgactgt attctctagc tgttttttct tttttgcgaa acagtttgtt
    14401 catgatccct ttttctattt ctacaactaa gaatagaaga atcacatttg ctccaatcaa
    14461 taactgttgt gtcatcgtta aacttactgt accgatcagc tgctggccga ctggtagaaa
    14521 aataaccatc ccttgcaata aagcaaggat acctaatgaa agaaaaagcg ctttgttttg
    14581 caaaagacct tggttcaatg acggcttgga caactctctg caattgatca tgtaaacagc
    14641 ttgagctaag acgatatttt gcagaagaat ggtttgctgt aagctttgcc cttcaaactg
    14701 catagccaat aaataggcag gaaccatgat cagtagggag acatagatga tccgaaacaa
    14761 atgataacca gataggattc cttgctttgg atctcttggt gggcgcttca tgatttctgg
    14821 atctggcgac tcgaacccta gtgcataaga taaagtgatt gtcgttacca tattgaccca
    14881 taaaatctgt actggggaca aaggtagcgg gcgattcagc ataagtgccc aaatcaagat
    14941 caatccttga gctaatgcag ttggcaagaa gaaattgatg gttttttgca aattatccaa
    15001 aatccgccgg ccctctttta cggcttttgc aatcgtatgg aaattatcat ctcctaaaac
    15061 catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcaa ttcctacatc
    15121 ggatcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc
    15181 atttttctgc aaagctttaa caattcgcag tttatgttct ggtgtcgttc gagcaaagac
    15241 atcgactatt ggcacttgct gaatcaactc ttcatcagac ataagatcca aatcgatccc
    15301 ttctaaaact ttggcagtat gttttaagcc aatttgttcc gcaatcgctt ttgctgtgtc
    15361 tttgtgatcc cctgtaatca ttttcactga gatccctgct tgttggcatt cctttacagc
    15421 tttgactgca ctttcttttg gcggatcgat caatccggcg atccctgcaa aagttaattg
    15481 ggttaaagtc tcatgcgtga gttcctgttt cgaatctact tttttataag caaatcctaa
    15541 aacacgctga ccttttctcg caaattctgc agctgtctga ctccatgctt cttgttctgc
    15601 agaagaaaga gttgatttag caaataatac ttctggtgca cctttgacgt aaatcaccgc
    15661 tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagaactga acggaatctt
    15721 tgcttctatt tttttcaaag gtagattggc tgtttctgtg tgtcgaatca gcgcaacttc
    15781 tgtcggattg ccacttaaat tttctgtttt ctgttcttct tttgttttta attcctgaca
    15841 gtttttcata atggacaaca cgcaggcttc ttcttttgca gctacatcca caactgtcat
    15901 ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc actgtcatag aacctaatgt
    15961 ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt gccatttcat gtactccaac
    16021 ggatagaatc atggtcaaaa cagctggcaa tccttcgggt accattgaca ccaccaaagc
    16081 aatcgtagcc gaaagaagga tatgccaatc cataccatat cgaaatgtcg taaaaataac
    16141 taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt ttgtttaatc ggttgatttt
    16201 tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat gcttgattga ttttaccgat
    16261 ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt
    16321 tcctgaaaaa cccatatttt tctggtcgcc gatcgattct tcttctgtca aaacggcatg
    16381 acttttttca gatgcttctg attctcccgt caaaatcgat tcttccacta ataaatcatg
    16441 tgcttcgatt aatcggatat ctgctggaac gacatctccg gcacgtaaga caatgacatc
    16501 tccttttacc agttctttcg cagggatttt ttcttgcatc ccgtttgata gtactatcgc
    16561 ttcttgtccc atcagctgct tcaaaccatt caatgattct tccgcttttc tttcttgcca
    16621 gtaactaacg agtccattga cgatcactac gaataaaata atacttcctt caatatattc
    16681 actagaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa
    16741 atgctttgct atttttttcc atcgttttgt ctgctgcctt gcttttattt cattatatcc
    16801 ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag ccttctgttg atgtttgata
    16861 gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta
    16921 attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg
    16981 tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac tgatatttct attgcttatt
    17041 cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt
    17101 gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga
    17161 tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac
    17221 aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa
    17281 aacaatcgac tatcagctac aaaaaaatgt agacaaagac cggcaaaaaa taacattcct
    17341 gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc
    17401 aaactttttt cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt
    17461 gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc gccttggcaa
    17521 tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga
    17581 acaacaaata aaatcgacaa aatcgttcct atatagaaaa agagaatacg ccaaggcaga
    17641 cagttgattg cttttttcaa attcttttgc ggatcacttg tctcgccaac ggttaagccg
    17701 atcatttcaa ttccagcaaa actgaataaa accataggaa atgagactac cattccagca
    17761 aagccaaacg gtagtaattc atcgatctgt ccaaaatttt ctttgattcc gatagactgg
    17821 gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag
    17881 atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg
    17941 actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac
    18001 cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa
    18061 agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa
    18121 tcactgatag agttaaatgt actatttgct aaaaataaat cacccatggc ccgcatcaaa
    18181 ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca
    18241 attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac
    18301 tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt
    18361 ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat
    18421 acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca
    18481 tgttccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac
    18541 gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt
    18601 caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat
    18661 acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat
    18721 cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt
    18781 ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct
    18841 agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac
    18901 accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg
    18961 gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac
    19021 atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa
    19081 tactccgcga atatacgttt taactggatt ttccaatcga gtgatataca cagaggacat
    19141 ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt
    19201 agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc
    19261 aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc
    19321 taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt
    19381 gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg
    19441 cacattatcg ataatattac caaacaacgg agcgagtgct gaagcgacca tcaccatccc
    19501 aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc
    19561 attcgatacc caaagttctg gaccaccttt ttggggaaac attccagcaa attcaccaga
    19621 gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt
    19681 ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat
    19741 tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc
    19801 ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga
    19861 caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt
    19921 agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa
    19981 gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca
    20041 aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt
    20101 ggatgatttc gtttagtttc ttttccattg ctttggcgat tttttttgta taaaaattga
    20161 aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct
    20221 gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat
    20281 caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat
    20341 cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca
    20401 aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca
    20461 atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc
    20521 tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca
    20581 atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt
    20641 ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac acatatggcg
    20701 cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat
    20761 aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc
    20821 tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt
    20881 caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg
    20941 aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt
    21001 ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg
    21061 ttcctacgac agcaaccaca cctagaattg ggattttttg tccagctaat tcacgaattg
    21121 ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct
    21181 gatctaagcc gactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag
    21241 ggaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga
    21301 cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata
    21361 aattcaaaag ttcccactca gacatttttt tcactttttc aggcagcact tccttgacag
    21421 ctaaaggaat cgatttgatg caacgggcgt accataatcc ttcaagatta gcaatagaac
    21481 catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc
    21541 ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt
    21601 tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt
    21661 gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga
    21721 cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat
    21781 ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt
    21841 catctaccat cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta
    21901 taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa
    21961 tgtcttgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga
    22021 attttttttt tataacatca aatccacgta gatttttaca aacaaaaata aataaagtcg
    22081 gatttttctg ataattcaac gcaaaaaagc gaacaatttt tcaataaatc agtcttctaa
    22141 aatagataac ctaaaaaaag cgaacaaaca aataaaatga ctgtccttca ttcactaaac
    22201 atatttttat ttttttatat tgttaaaaat tcgcaattta ttttttaata gaattatctg
    22261 ttttccaaat tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa
    22321 attaactgat gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa
    22381 tacaaggcgg aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc
    22441 tgtttttatg tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc
    22501 tcctgcatgt ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg
    22561 aagaacagat cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac
    22621 atatacctcg atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt
    22681 gtctgcttta tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca
    22741 tctctgtcag caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg
    22801 ggatcgaaat cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc
    22861 ttaatgtgtc gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg
    22921 aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag
    22981 aaaataaaga aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg
    23041 ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg
    23101 tcgaatcagc atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct
    23161 ttattttgac actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg
    23221 aagactttca acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag
    23281 ttgctacctt tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg
    23341 cgctgattca tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat
    23401 tttatctttt acatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca
    23461 gctggtccag ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg
    23521 tgatcgaatt gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca
    23581 caaattcgga tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg
    23641 attttcaagt tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc
    23701 agtcctcaaa ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg
    23761 aaaatattat tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa
    23821 acaaataagg ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat
    23881 ttctgtaaca atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac
    23941 gggtccgatc tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc
    24001 tagttggaaa atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac
    24061 aagaatttcc aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc
    24121 gctgactcgg tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat
    24181 tgatagacaa acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag
    24241 tttttcgaaa tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt
    24301 ctttgttttt ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg
    24361 ataataataa gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg
    24421 atatcagcaa cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt
    24481 gtatctgcat tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa
    24541 agtttgaata gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa
    24601 atagcaatga tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac
    24661 tttcttttaa tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt
    24721 aaaagttgtt ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc
    24781 tccctccatc cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt
    24841 agtccgtcat cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc
    24901 taaaaataga accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta
    24961 caggaaaatc agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca
    25021 tttggcattc taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt
    25081 ttttcatgag taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg
    25141 ctgcatatct aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat
    25201 tcgaatcaat ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg
    25261 aggaatcaca atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc
    25321 agcggctgtt tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc
    25381 attggatgat cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg
    25441 gaataaaaac catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct
    25501 taattaccgt acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga
    25561 gccagggatg actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga
    25621 caaagcacgt ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa
    25681 taataaagac cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa
    25741 actagacaat atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa
    25801 cttctggttt atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt
    25861 gcgtcgctat atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt
    25921 caatcgaaca cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa
    25981 agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac
    26041 accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga
    26101 agaagaatac gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac
    26161 agattcagct actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc
    26221 agcttctagt ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa
    26281 attctttgct gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca
    26341 tttgttgttg aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc
    26401 atttatttca accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctatcgt
    26461 cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta
    26521 tttcctttat ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg
    26581 aaaagaaatg ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa
    26641 tattcgtgaa aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat
    26701 gccttatgct tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc
    26761 taaacattcg accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat
    26821 ctttactgaa caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat
    26881 tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg
    26941 tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt
    27001 aataagaaca accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc
    27061 gcagatgcaa gcttttgaac accgtttacc aagaggttgt gaaaaagctg ccctgcatca
    27121 agtaataaga acacccaagc taaaactgct tcttatgttt ttgacttggt tggacttatt
    27181 accgcagatg caagcttttg aacaccattt accaagaggt tatgaaaaag ctgccctgca
    27241 tcaagtaata agagcagcca agctaaaaca gcttcttatg tttttgactt ggttagactt
    27301 attaccgcag atgcaagctt ttgaacaccg tttaccaaga ggttatgaaa aaggcgttta
    27361 gtttcgagta tgaagaaaaa ttttgtgaaa atggttcctc acgtttttgc ataaatttga
    27421 cttaataccg agaaactgat cccttctgtc ataacctctt tttatttatg tctgtttctt
    27481 tttgaaaaca actatttttt caacgtttac tctcttgcca atccaacatc atctaacgga
    27541 tacaactatt tcaatgatta ccattacact aaaaaatcgg aaacacacct ctccgaacac
    27601 aaatacataa gactatagaa tgtttcattt aagaaaaaaa gcgtttcatt atcaaaaagg
    27661 taagatctcc tttaaaatga aattatctgt agtactaata atgcagacaa ttttatgaat
    27721 ctgaaaggag catctccaat gaaagcagtc acttggcaag gaaaacagaa aatggaaatc
    27781 agaaacgtag atgatccaaa aatattagaa ccaacagatg caatcatccg tatcacagca
    27841 acagccattt gcggctccga tctgcatctt taccatcatg gtgaagcagt tttggaaaaa
    27901 gggtatgttg taggacacga accaatggga atcgttgaag aagtgggatc tcaagttcaa
    27961 acattgaaaa aagggcaacg tgtggttatc ccttttaata ttagttgtgg tcattgtcat
    28021 ttctgcctga atcacatgga aagccaatgt gatgaatcaa atccagatca gttatatggc
    28081 gggcttttcg gatttggcaa gttgaacggt aatcattggg gtggtcaagc ggaatatcta
    28141 agagttcctt atgcagactc tacttcattt gttgtaccag ataatgatct tcctgatgaa
    28201 aaagttttat ttctatcaga tattttgccc acagcttatt ggagcgttga aaacgcagga
    28261 gtaaaaaaag gcgatacagt tgtgattcta ggttctggtc cagtcggtct attcgctcaa
    28321 aaattcgctg ttatggctgg agcagagcgc gtaatcgcag tagatccagt acagcaccgt
    28381 ctagataaag cggctaatta caatggggtt gaaacttatt tcttagaaga cacggcacaa
    28441 gctggaacag aattgtatga actggctaaa ggtggcgcag atgtcattat cgattgtgta
    28501 ggaatggacg gattagagcc tgtcaaagaa aaagcgaaaa atttagtaag cttacaaagc
    28561 ggcacaatct ctccattaca gatggcatcg caagctgtca aaaaatttgg aacagtccaa
    28621 gtaactggtg tttatatgac tccagcttct tcttacccgc tgcaagaatt ttttatgcgg
    28681 gatatcgctg tcaagcatgg acaggcacca attatccatc taatgccaaa aatttacgca
    28741 atgattgcag aaggactatt cgatcctaca caaatcatta ctcattcgct gccactatca
    28801 gaagcagcac aagcatatga gatctttgac aaaaaagaag ataaaaatat aaaagttgtt
    28861 ttgaaacctt gaattcagta aaaaatacag gtgattttct ttatgcccaa aatcaaacga
    28921 aatacccatg agatcgaaat aggaaaagaa gaagatatcg aaatacgagg acgtcgcttc
    28981 cgcttctatt tccaaaatcg ttacacattg atctcactgg ctgtcgattt attaaccggg
    29041 attttctata tttttggaag ccttgcttcc ttaactaaaa tccccgatcg atatggcacc
    29101 tatttttatt tggctggtgc tattttcttg acgattcgtc ctattctcag aatcgtaagg
    29161 aacattttta tttacgacga aaaaaaagca atgaagagaa caagcaaaaa aaaagaggca
    29221 tgagaatttt tcaaatctca tgcctctttt ttcaccctat cgtatcactt tgatacagac
    29281 gagcggtcgt cccactttct tccttgacca ttgtcaaaaa tgtccactcg tatcgttcat
    29341 aaaacgtggt atgatctgta attaagtaaa gtttttcgta cccaagttga tgcatttctt
    29401 ttctgatttc cgctaatatc cgcttggcta tcccctgctt acgcttttcc ggttcaacaa
    29461 acagggcaca aagatttggt gtcagatcag ggcggttatg gaagtcgttt tcaatgacgc
    29521 ccgctcctcc gacgatggtt tctttttcat ctaagaccac ataccattga ggaatacttt
    29581 ccttattagc gattccagta cgaatacttt cctcatacac aacagcagga actccccatt
    29641 ttgatgaaaa ccaattcgcg ctttgtttta ctaattctgg gtgttctctt aatttgatcc
    29701 agttatatgt aaccaatgtt taaacctccg actaaaataa aacgtttaca aaaattatac
    29761 aagtctttat gaaaattagc aatgacaaca atagtgatgt aaaaaaaaaa cggaaaacaa
    29821 tcacttgttc tccgtttttt gattaatcaa gcatctaaag cttcttttct tctttcttgg
    29881 atcgtagcta ccttgacgaa cggtagatag atcaaaatag aaagaaccaa attgacagcg
    29941 gctagtacac cacctgcaat actttttgtt gccaatacac cgccaataat tggtggagtt
    30001 acccatggag gcataacggt agctgctggc actaaacctg tagaagtcgc aaagtaagca
    30061 acactaacta agaccattgg tgtcaaaata aatggaatga acatgatcgg gttcaacacg
    30121 ataggtaacc caaacatcgt tggttcatta atattgaaga cacctggcgc aatcgacaag
    30181 tttgttacaa ccatatatgg tttgttttta cgtcctacta aataaatagc taacagtaaa
    30241 cctaaagttg cacctgttcc tcctaagttg acaaagctgt caaagaaagg tttgttcacg
    30301 ataaacggtg cgctatgccc agctgcgatt gcattaacgt ttgcttcaat ggctggcgca
    30361 ttgattgttt gcatcaaagg atcgaccata ttcgctccgt gtaaaccaaa gaaccataag
    30421 aatggtgtga taaatgcaag cagtaaggca gatggataag agtttgcaag tcccataaat
    30481 ggttcttgga ccactgtata gaaagaacct acgatatcat caacaccgaa tgcagcaaaa
    30541 attgcagcaa ctaaagcaaa cgcagagata gtgatcattg ctggtagtaa tgaagcaaat
    30601 gcttttgcaa ctgccggtgg cacaccatca ggcattttga tgatcaattt ttcatttccg
    30661 cttaaacgta caaagatttc tgttgaaata atcccaacaa taatagcaat aaacaaaccg
    30721 tttgagctca tacctaatgc tccgcctaaa gcgaagaaag agcctaaaga aatcacacct
    30781 gcggaaacac cgtcttttcg gtagccgtta gctaaatgat aagcaagcaa gaaagcaatc
    30841 aagacagaaa gaatggcaaa tgtaccgttc caagcagcag ccccgaatcc tttccatgat
    30901 tcaccaccaa aaattgagtt catcaattct tggaacccgg gaatcggtaa gttattgatc
    30961 attactgcta atgctcctaa gatcattaac ggcatactca ccataaatga gtcccgaatc
    31021 gcaactaaat gccgttgtgc accaattttt gatgctacag gtataaaatg tttctccata
    31081 aatgcaacaa atttatccat aaatcttccc tcttttcttt actgtagatt acgcgttcaa
    31141 tcgacgatac agatcaatga tctcttttgc taaatctgta aaagctatag atgtcatcag
    31201 atgatcttga ctgtggaccg tcaaaagcgt gacttcaacg tgatttcctt gtgcttcttg
    31261 tgtcagcatc tctgtttgag agtgatgtgc ttggactaaa gattcctctg catctttgat
    31321 tttttcatct gctaaagtga aatcaccttt tttcgcagca gcaatcgctt ccattgcatc
    31381 gctttttgca tttccgccaa acatgatcag acccatgatg gcttctagat ttttttgatc
    31441 ttccatttat tgtatcctcc gataattttt attatttgtt tattagtttt tctgcttggt
    31501 cgagtacttt ttcaccattc atcatgccat agtcagccat attgattaca tctaaaggaa
    31561 tgcctttagg tgctagcttt tcagcaaatt gattttgcat aaagcgtact tgcggtccta
    31621 aaagtaaaac gtctacattt ttagattcta gttgattatc cgcatctgaa gcagatacag
    31681 caaagatgtc tgcttccatt ccttttgctt ctgctgcctt ttgcattttt gtgactagga
    31741 gacttgtact cattccagct gaacatacaa gcatgattgt tttcttttcc attttaaaca
    31801 cgttcctttc tatacttaca cttgtatata agcaagtagc gtgccaactt taaaagcgct
    31861 ttaaaaagtt gatatcatca catttaaggt ctataccaag ttgcatacac actaaaaaag
    31921 aaagcgcaca ctaaacacac aaattaattt ttattacctt ttttctttta acgtgcacaa
    31981 aaaaagttgt gacacaaaac ttgtcacaac ttttttcaaa taaacggtat tcaaaagctt
    32041 gcatctgcgg taataagtcc aaccaagtta aaaacataag atgttgtttt tactttgcta
    32101 ttcttattac ttgatgcagg acagcttttt cacaacctct caataaacgg tgttcaatca
    32161 gctgaccctg ggtattagct caaaacgctg gattcacaac ctcttttatt tcaaataacc
    32221 agtaaataca atgaacatct acaaaaaact tctatttatt tatagatttc gtcaggcaaa
    32281 tccaattctc tcttatcaat caaagtctga taccacgaag cagatttttt caatgttctg
    32341 cttcgttcat cgttcaattc gattcgaact aatccatatc gattcttaaa tgcattcatt
    32401 ggtgacacac agtcagtgaa tgcccataac atatagcctt cgcaatttgc gccttcttct
    32461 gttgctttga tcaagtaatg caaatgctgt ccgataaatt cgatacggta atcatcttgc
    32521 acgattcctt tctcatccat atactgttct tcatattctc ttcccatacc gttttctgtt
    32581 atcagccaag ggatattatg ataattttct tttagataca tggctatatc atacatgatt
    32641 ttcggataga tttcccatcc cctggaatta ttcattttct tcccaggtaa atcaaagact
    32701 tcataatatc gttcaggatg gaaaggtgtc tcttcattcc attgataacg aggggcgcga
    32761 acgcgtttag gataatattg attgattcca aggaaatcta ctgtatgatg ctgaatcgtt
    32821 tctaaatcct ctgttgcagg atcgaaataa atcgattgtt tttgacacaa ctccaggaac
    32881 tcttctgtgt agtatccttt taccatcgga tcaaaaaata ctcgattata aaacaaatca
    32941 tacatataag cagctttttg gtcttctgga gaattggatc gagcatagac catttcagga
    33001 tttaaaatac agccaatcct tccaccataa tttccgctgc ggtaaatctc tactgcttta
    33061 gccgttgcta aaactttatg ataattccac atcatccact tttttgtgtt ttgttcatgc
    33121 ggccagcgaa cagcatccaa atagcaacgc gtttggggaa cgattggttc gttgaatgta
    33181 aaccagtttt ttaccctatc accgtaacga tcaaaggcaa tttgagcata cttagcataa
    33241 aaatcaacta cttttcttga agaccagcca tcatattttt ccaaaagaaa agctgggact
    33301 tcataatgtt ccaaacaaat catcggttct acgtctgctt cgatcaaaga gtcgatcatt
    33361 tcacttatat gctgagcata ttcttcatct actatacagt tctcataatc agtaaaaaaa
    33421 cgagcccaat tgatagaagt ccgataatgt gtcagatgga tggatttcat cagatccaca
    33481 tcctgctggt attgttccat aaaattagtt gctacggctg ggccataccc attatgccaa
    33541 acaaaatgtt catttttata ccagctatct ataaacgaat cctgtccttc tttttttcct
    33601 ttccaacctt ccgtttgcca agcagaagat gcagcaccaa gaataaaatt ttttggaata
    33661 gtaattttca tgatttcctc ctgtttttta gatcccatca ttttccacac gatttgctac
    33721 ttttacaaat ggcagataga tcaaaataga aacaataata caaacaagtt gcgtaataac
    33781 tgcaccgata tttcctgctg ttgccagata agcattgacg atcggcggca ttggccaagg
    33841 gaccattaca actgctttcg ccgcaaatcc taaagcggtt gcaaaataac caatcgttcc
    33901 agtgataaga ggcgttaaga taaacggaat agctaaaatt ggattcagca tgatcggcat
    33961 accaaaaata actggttcat tgatgttgaa gatcccagga gcaagggata acttggtgat
    34021 ttgtttcata tcttcccgtt ttccaactaa caatactgca atcagtaaac cgatcgtgac
    34081 tccagacccg cccatactca tatacatatc ccaaaatggc atagtaataa tgttcggtac
    34141 ttcttttcca gcttcaaaag cttccgtatt tacagcaatt gccgctaaaa gcaacggttc
    34201 ccgtatcggc ttcaccattt gatttccatg gataccaatc acccaaaaga cttgcgcaat
    34261 aaacatcaat agcaaaatac ccggtaaccc ttgtacgaca ccttctaatg ggcgttgtac
    34321 gacattgtaa atgatatcat aaaggtacat tcctgtaagt tctttgatga taaatcccgc
    34381 agccgcgata cccgatacag tcagaatcgt cgggaataaa gcagaaaaac tagcagaaac
    34441 attcgttggc acggtatcag gcattctcag ctgtagtttc ttctgtttcc tcaaccagca
    34501 ataaagttca atagaaagga tggagaccaa cattcccaaa aataaccctt tcgtatctgt
    34561 atattgttta gccaatacgt tttctactat aacagtctga ttttcattca ctaattcata
    34621 aacagttgga ttaacagata aataagacat cactgcgatg ataccaggga atacaccatc
    34681 cactttattc agcttggcta attcgatccc tatcagaaaa acagcataga tggtcaagaa
    34741 acttagtgtg acatagctga tggcagatgc gataggcttt aattcttcta aaaaacgcaa
    34801 gaaacttatc tgtgctaagc cattttccga gtcaaagacc attgctgaaa acaatgtgcc
    34861 aaaagcaccc gtaataatta ccggaatcaa tgcagcaaat gcgtttttta tcaccatgat
    34921 ataccttaaa ttattgattc tcgttgccac gttccctaaa acattggcta atttatccat
    34981 aaaactcatt ccagatcccc tcattcctgc ttcttctcct tgacgtcatc tctttttgtc
    35041 tattagtcag cgcttacatt tcgatgaaca gaaactattt actcctcttt tttaccaaat
    35101 ataaaacaaa aattcatctg atgtatttat cataaaatac atcagatgaa ctgtcaatta
    35161 gtttcttttt ctcctattat tttctgtaat tctctccgat ttattgccat atggacagtc
    35221 attgcatcaa acgcagcaag tgcattccgc ctttcgatgg cctgaacgat ctctgtatga
    35281 atatcgatcg tctcgatttt cagatgctgg atatcataat ttttattaaa caaagcaatt
    35341 gattcattaa tgattgggat aatatgcagc aaggctacgt ttccgctagc ttctgcaatc
    35401 atcgtatgaa aatcgatgtc taattgaaca tgttcttgtg tgccttctcg aaaagaagtt
    35461 tcaatctttt gcgttaattt tttcatttgg acgatttgat tcttcgttgc atattccgct
    35521 gccaaacctg ccatcttagg ctccaataaa tatctcagtt caaataagtc tcgtatcatc
    35581 cgatcctgat cttcaatcaa agaaaaaccg agtgggtcat tggcaatccc tcgcttatca
    35641 ctgacaaatg tccccgctcc ttgccgaact tcaaggatat tcctggaagc tagagcccgc
    35701 acagcttctc gcaccgtgct tcgccccacc tctaaataat cggacaattc atattcattc
    35761 ggcagtttat ctcctacttg caactgcatt tcctttaaat atctaaggat cttgtcagta
    35821 gttacttcta ctagggtttt attttcttcc aaaccacata cctccttttc atctgatgta
    35881 ttttttcgta attattataa cacgtttgaa tcatctgatg attttttgta tacaaaattg
    35941 attaatccgt tcatagacat acaaacgaag aagatattta ccataaaaaa gactaggata
    36001 aaattcactc ctagccttcg atcattttta ttttgaacga caaaaaatat gatgttcaat
    36061 aacagacgat cttcattcga ttcttgatgt catcttttgt tttttttaat atatggataa
    36121 aaagtttgat tacatcgttt ctattctaga atttggtcga ttctcaattc ttcttctggt
    36181 gagaaatcta aattatccat cattcgaaca ctttcttgta actgacttaa ccgacttgct
    36241 ccgaccagta cacttgtaac agatttttgt cgcaaattcc atgcaagggc catttgcgct
    36301 aatgattgtc ctcgtgatac ggcgattgtt tgcagtgctt tgattttttc cagagttgat
    36361 ccaacttgtt cttctgaaag gaatggtatt tccttacgat gtgctctaga atcttcagga
    36421 ataccatgta gataacgatt tgtcagcaac ccttgagcaa gcggactgaa cgtgattgcc
    36481 cctagccctt cttcttctaa tactggagat agatcgtctt ctagtagtgc acgagaaaac
    36541 atattgtagc gcatctgatg aataatgaac ggtgcttcct ttctttttaa aatttcagtc
    36601 attttttttg tatcttctcc attatagttg gatataccaa tatataatgc ttttccttgt
    36661 cttacaagtt gcatcaaagc ttctgctgtt tcttccaaag gtgtatcagg gtctgggcga
    36721 tgatgataga agatgtcaac ataatctagc cccattcttt ggagactttg gtcacaactt
    36781 gaaatgatgg atttacgaga gccccattcc ccatatggcc cttcccacat atgataacct
    36841 gctttgctag aaataatcag ttcatcacgg taggcttgaa aatcttctct aaaaatacgc
    36901 ccaaagtttt tctctgcagc tccagcaggg cctccataat tattcgcaag gtcgaaatgg
    36961 gtaattccca tgtcgaatgc gcctcttaaa atctctcttt gattatggat aggatcataa
    37021 tcaccaaaat tttgccataa tccgagagat aaaatcggta atttcaaacc tgaatgaccg
    37081 gatttacgat attccatttt ttcataacgt gcactatctg caatatacaa tttttctcct
    37141 cctcatcaaa tctttttaaa acgctttctt ttttctattt ttagtttact acattttaaa
    37201 gaaaaggagt taatcaaaat gattttttcg tatatttttt tgccatttgt tttttactcg
    37261 ttgatagatc agaaattgat tacgtgcttg ctggattttt ttataacgtt tcggttgttt
    37321 tttgtaaaat tgctgatgat agttttctgc tggccaaaac gtaccggctg gttcgatttt
    37381 tgtgacgatt ggttggtgga aagttcctga actgtctagt ttctgttttg attgttccgc
    37441 taattctttt tgtcgttcgc cttgataaaa aatcactgga cgatattgct tccctctatc
    37501 ttgaaattgt ccaaatgtat ctgtgggatc agtaatttgc caatagattg tcagcaactc
    37561 gctataactt atttctcttg tgtcataaat gatctccaca gcttccacat gacctgtgta
    37621 accaccactt acttgatcat aatttggttt ttcaacatgt ccgcccgtgt atcctgacaa
    37681 aacagatagg atcccttttt tcgattcaaa cggctcgacc atacaccaga aacatccccc
    37741 tgcaaatact gcacgttctt gatagtcagc atcttgcatg gcatgcttgg aaaagtcata
    37801 tttttgctcc ttatcaaatc cttccgtaat caataaataa aagtccatta catcaggcgt
    37861 cagattcatt cggatagcta atggacgtag tgttgcttct agttttgata actgttcttt
    37921 aacggatata ttttctctta tgtcattctt tgtctgaatc aatacttttc gttcccaatc
    37981 tcgtgtattc ggattcaaaa tcagattata aagtgtttga atgaatattt gttcctcatc
    38041 catagattct cctcctttcc gaagaagaca agctagtgac tttagctgta atttatcata
    38101 aagtgaggaa ataagcgatt acttcatccc cctacagatt tttcgtataa aaaagagaga
    38161 atccttatcg acagattctc ctttttaatc aatttatttt ataaatgaaa agttaattta
    38221 ccttttatgg aaaactattt taaaaaataa acataaatat gcagttaatg taacaagata
    38281 agaaataata gtcgttactg tataacttgt gcttacttta atatcagcaa ctcctttgac
    38341 tccgcttatt tgtaccaatc cattagcatt cacctgctcc tttacaggtt gatgatttat
    38401 ttctacattc gttcctaaat aagcatatac aggaagtgtg attacttggc tcttctcatt
    38461 agttactcta tatatgatag aactaccagt tgttttataa ggaaggttta cccattgact
    38521 gccaatcttt gcttcgtgtt ttattatatg ctccttattc tccaatgaag cgataggaga
    38581 ataatcatat aaaaaataat ccattccttt agtggtatac gcctctactg tttctttgtt
    38641 tacaacaata tgtcccggct gagaaattat tttttgattg aaattttttt tactagaaac
    38701 agttaaagtg attaataaca aaacagtcat aaataaataa aatagttctc ttgtcttatt
    38761 gtatcttcta tttttgaaaa atatcatcgt taatatcaga gaagagaata ttatttgcaa
    38821 gcttaagatc cgccaaggaa attgtaacaa tttggctggc gtattttgca gaagatacca
    38881 tggcaccaaa ctagttgtag ctagccaagt caaacacgta ccataataaa tctttttttc
    38941 tatgtttgtt aattttttaa ataaaatcag gggaatacat aaagataaca gaccaactag
    39001 tcccattgag taagtagtta agtcgttgtt catagcttca gtcagactat cgaacacatt
    39061 agatgcatga gcatataaat ttgtcacgct aggtttgttg attttttggt agagcatttg
    39121 ttcaaacatc ggataccaaa aagcactcgt cagaaccaat gtcattcctg ccgcactaaa
    39181 taatttttta aatatagcaa taaaatctgc attcttgaaa cctttagaaa ccaaacgaat
    39241 aaaaataaaa atgataatta atgctgtact cattaatgtt gatagtacat ggctgtacac
    39301 tagcaaactc atactcaatg ctagctttac agacggatac ttttcttctt ttccagagat
    39361 gatttgataa gcataaaata atacagggat aacaagtgtt attgcgatag cttcggcaat
    39421 tgcggaacga tagtagatgt ctactgtccg ataagcagag aaaatataga gacaactaaa
    39481 taaaaatgcc gctttttttt gttttaaaaa ccgctcgcca taatgataag ctacgagtgt
    39541 tgtacacaag ttcaataacc aaacgtaaat aatatagctt acaatcaaat tttttgtcat
    39601 ccaatataac attacagctg gaaaaaaagt cagaaaggga taaaaataat ttacaccata
    39661 tccagtataa ttgaatgtct cataattaat cggactggta aaaatagtcg ataacccctt
    39721 gattcgagat aagtgaaaag aaagatctcc agtggtataa atactctgtg tatttttgaa
    39781 aaagatgaaa gaatatatac tactaactat aattaatcca ctcaatatta ctactttttt
    39841 atttattttc attcttcttg tttatctcct ttttagtcac atatcgagaa tctttcaact
    39901 tattaggtgc aaatcgttta aaacttgaat acaccactaa acaataagtc agaatactga
    39961 tccataaagc catgagagca gttggagtat attttgttgt aatttctatc ttattttctc
    40021 cagcatttac atccacattc actaagccat gttttttata agagtcattt acgactttac
    40081 cgtttacttt tacctgtgta cctaaataag catatactgg tactgtcact ttttgctttt
    40141 tgttgcttgc cactgtgtaa gtaatgttat tatctgcagc tttatacttc cctttttccc
    40201 acgattctcc tacttttact tcatgttttt ctaagtgagg cctttctttt atcgcttctg
    40261 ttggggcgta atcgtataat cctcccatat ctgatgttgt ataacgtggg agtgtttctt
    40321 cattgataac aatatgaccg tgttttgatt ggataacttt tgcgtaattt tcttttgctg
    40381 ctatagacgt gacgagtaga aacaccacag tagcgccaat gattaaccat gaatattttt
    40441 tattcatagt ctttttcata aaaacaagcg ttatgatcat tgaagaaaaa aagatttgga
    40501 tacctaagat acgccaagga aactggagca agcttatcgg tgttttttga aacaaaaacc
    40561 atggaaataa attagttacg catacccatg tagaaactac gccaacatag atgatttttt
    40621 cttttttctc catttctttc agtatgaata aaggaaaaat caacgcaacc aatcctaata
    40681 accccatagt gtatgttgta atatcgttat ttaacgcttg aatgatacta tctgaaatag
    40741 aaagtgcttc tagctgcaaa tctgttttga agggactgtg tatttcttga taattcatct
    40801 gctgcaacat aggataccaa aaatagctag ttaatgcaca agtcaaaaaa acagccttta
    40861 ctaaattcac gaccacaaat tttatatcgt tttttatttg cttgcttaaa aacaaacgaa
    40921 ctataatcat acaagcaatc aatgcactac acaatagtgt agttaagaca tgagtataca
    40981 caagtagact tatactgaca gataaagcga tgactttttt ttctctattg aatatcaatc
    41041 cataagcata atataaaaca gctgggataa tcgtaagagc gattgcttct gcaattgcgg
    41101 atcgataata gatatcaact gttcgataag ttgcaaaagt atataaacaa ctaaataaaa
    41161 aagcagcatc tatcttttta aaaaactttt ctccataata aaaac
//
LOCUS       DAKCAA010000020        40816 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000020 DAKCAA010000000
VERSION     DAKCAA010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.020"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            23..646
                     /locus_tag="OUE31_001168"
     CDS             23..646
                     /locus_tag="OUE31_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222188.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="OUE31_001169"
     CDS             1096..2145
                     /locus_tag="OUE31_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCU0222189.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="OUE31_001170"
     CDS             2142..3023
                     /locus_tag="OUE31_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222190.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="OUE31_001171"
     CDS             3026..3796
                     /locus_tag="OUE31_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0222191.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="OUE31_001172"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="OUE31_001172"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HCU0222192.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="OUE31_001173"
     CDS             5107..6270
                     /locus_tag="OUE31_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCU0222193.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="OUE31_001174"
     CDS             6387..6797
                     /locus_tag="OUE31_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCU0222194.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="OUE31_001175"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="OUE31_001175"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCU0222195.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="OUE31_001176"
     CDS             9370..9654
                     /locus_tag="OUE31_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222196.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="OUE31_001177"
     CDS             9814..10050
                     /locus_tag="OUE31_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCU0222197.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10446
                     /locus_tag="OUE31_001178"
                     /pseudo
     CDS             10047..10446
                     /locus_tag="OUE31_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
     gene            complement(11113..12057)
                     /locus_tag="OUE31_001179"
     CDS             complement(11113..12057)
                     /locus_tag="OUE31_001179"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCU0222198.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNATYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12353..13297)
                     /locus_tag="OUE31_001180"
     CDS             complement(12353..13297)
                     /locus_tag="OUE31_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222199.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13518..14732
                     /locus_tag="OUE31_001181"
     CDS             13518..14732
                     /locus_tag="OUE31_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0222200.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14754..16769
                     /locus_tag="OUE31_001182"
     CDS             14754..16769
                     /locus_tag="OUE31_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HCU0222201.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16852..18225)
                     /locus_tag="OUE31_001183"
     CDS             complement(16852..18225)
                     /locus_tag="OUE31_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCU0222202.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18251..18535)
                     /locus_tag="OUE31_001184"
     CDS             complement(18251..18535)
                     /locus_tag="OUE31_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0222203.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18537..20552)
                     /locus_tag="OUE31_001185"
     CDS             complement(18537..20552)
                     /locus_tag="OUE31_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCU0222204.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20731..21036)
                     /locus_tag="OUE31_001186"
     CDS             complement(20731..21036)
                     /locus_tag="OUE31_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HCU0222205.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21125..22156)
                     /locus_tag="OUE31_001187"
     CDS             complement(21125..22156)
                     /locus_tag="OUE31_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCU0222206.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22363..23238
                     /locus_tag="OUE31_001188"
     CDS             22363..23238
                     /locus_tag="OUE31_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCU0222207.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23390..24232)
                     /locus_tag="OUE31_001189"
     CDS             complement(23390..24232)
                     /locus_tag="OUE31_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCU0222208.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24324..26201)
                     /locus_tag="OUE31_001190"
     CDS             complement(24324..26201)
                     /locus_tag="OUE31_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCU0222209.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26198..27619)
                     /locus_tag="OUE31_001191"
     CDS             complement(26198..27619)
                     /locus_tag="OUE31_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCU0222210.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27622..31011)
                     /locus_tag="OUE31_001192"
     CDS             complement(27622..31011)
                     /locus_tag="OUE31_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCU0222211.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31268..32659
                     /locus_tag="OUE31_001193"
     CDS             31268..32659
                     /locus_tag="OUE31_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222212.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32732..33379)
                     /locus_tag="OUE31_001194"
     CDS             complement(32732..33379)
                     /locus_tag="OUE31_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCU0222213.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33387..34073)
                     /locus_tag="OUE31_001195"
     CDS             complement(33387..34073)
                     /locus_tag="OUE31_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222214.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34079..35152)
                     /locus_tag="OUE31_001196"
     CDS             complement(34079..35152)
                     /locus_tag="OUE31_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222215.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35374..36048
                     /locus_tag="OUE31_001197"
     CDS             35374..36048
                     /locus_tag="OUE31_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0222216.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36053..37393
                     /locus_tag="OUE31_001198"
     CDS             36053..37393
                     /locus_tag="OUE31_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCU0222217.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMATIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37542..38528)
                     /locus_tag="OUE31_001199"
     CDS             complement(37542..38528)
                     /locus_tag="OUE31_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HCU0222218.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39252..40283
                     /locus_tag="OUE31_001200"
     CDS             39252..40283
                     /locus_tag="OUE31_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCU0222219.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40392..>40816
                     /locus_tag="OUE31_001201"
     CDS             40392..>40816
                     /locus_tag="OUE31_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HCU0222220.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT        12670 a         7414 c         7664 g        13068 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataatactg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagca
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggg ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta ccgtcactcg ccaggcgaaa tgatcggtgt aaaagatgca
    10141 aatgcattag atatggccgt caaacagcct tcacaagcag tattcaatca agaactctat
    10201 cctgaaatct atgaaaaagc ggcgatttta gcaattaatt tagctaaaaa acatcctttt
    10261 cataatggca ataaacgaac tgctcttgtt gccatgttgt tgtttcttca attgaataat
    10321 tgtccagttg ctttttctcg tcaagaagct gttgatttta tcataatgat taccactagt
    10381 tcattggatt tcgattcact aaagtccaag ataaccagtt atttacgaca aaccgcaata
    10441 aaatgaacga attaaaaact ttatttctca attagatcag catgtcatta aggaatatgc
    10501 tgattttttt atgtttaatc atacaaaata gttttttcat aaaaatatgg aaaatatgga
    10561 ttaattttga aataattgat ttaaaaggaa tacaaaagag tgaatagtag gaaatagtgg
    10621 tttagaacta gtgggctgat tttttatata ttttagttta cataatatat attatacaaa
    10681 gtagatttaa aaaatgataa acctctctcg aacggttttt tatcaaaaat cgtcattttt
    10741 ccatcaaaat ctgcttatgc aaaattataa aaaaattttg cagtttttct tacttttttt
    10801 gtcgtttaat tgaatgataa aaaccagttt ctttattcag ttaatcaaat atgaacgaat
    10861 tagatatgaa tcattgtatt tgccgttgcg gaaggatttt ttaattaacc acagataaac
    10921 attgataacg attcgcttat tgtaatcaac agattaaatt tcatatgttc atatgtacgg
    10981 atacattttc ggaccgatta attttaacca ttctgtttat ttgcttacct attagatatc
    11041 aataaaaaac tgcttaacag ctatttcagc tgttaagcag ttttaggatt tttagttcat
    11101 attcattgtt tcttataata cagtgttcaa tacttctctt aaagcacttg ttgatttgct
    11161 gaacattgct ttttcttctt cgttgattga taattcaaca acttcacgaa caccattttc
    11221 gtcaacgatt gatggcacac ctgtaaagat atctttttcg tcgtattcac cagttaaata
    11281 agcagataca ggcaatacag cttgttcgtt attcaagata gcttttacga tacgtgcagt
    11341 actcatacca ataccatagt aagttgcttt tttacgatca atgatctcat aagtagcatt
    11401 acggacttta tcagcaatca catctaattc atcttgggca atacgatggt ctttttctac
    11461 aatttcaaac actggtttac caccgacagt tgtatgtgac catgcagcaa cttctgaatc
    11521 accatgttca cctaagatat agccgtggac gctgcgtggg tcaactttta atttcaatgc
    11581 gatttcttta cggaaacgag ttgtatccaa tgttgttcca gtaccgataa cacgtgatgt
    11641 tggcagacca gattcgttcc aagcgatata tgtcaaaata tctactgggt ttgaagcaac
    11701 aacgataata ccgtcgaatc ctgatcccat gatttctttt acgatttggc gcatgattga
    11761 cgcatttgtt ttaactaaat ctaaacgaga ttgaccaggt ttttggttga taccagctgt
    11821 gataacaacg atatcagcat ctttacattc ttcatagcca cctgaccata cagccacatt
    11881 ttcatcgccc caagccatac catctaaaag gtccaatgct tccccttctg ctttttcttg
    11941 attcacatcg atcaatacta attcattaga gattccttgg ttgatcattg cataagcgat
    12001 acttgttcca acaaaacctg taccgacgat tactacttta cgacttgttt ttttcatgaa
    12061 taaacagctc cttttcataa ctatttgtta ctttcatgaa aagtatagtc ttgtttattc
    12121 attttatcaa catgttaatt ataatagttg ttattataat ttttgatgga aacgaattcc
    12181 tgaatacgca taacagataa atgacaaatg tttacaccta tatcccctga taatacaacc
    12241 aaaagtttag aactgaaaat aaatccaaaa aaattcgctg caacgatata ataagacagc
    12301 aatcgcacct aaaacaattt tccttcatat gctttagtga aagattttct tcttaatgtt
    12361 tatttctcca ttcattggga gtacatgttg aatacttctt gaataatttg aataaagaag
    12421 tcgtttgttt atatccgata cgattagcga tttcttccaa cgaaaaactc gtttcttgaa
    12481 tcagttccaa cgcaaagtcg aattttttct ttagaaccag ttcttgaaag gaagcatcaa
    12541 aatacatttt caatttatta ctaagataga ccggattgta gccaaaatga gctgctgttt
    12601 cttttaacgt acaagaagta aaatgcttat cgatataatc taatactcta agcatctcat
    12661 tttctgcgca tccatctgct gatgaaaagc tttgttgttc taataaatga gtcaattcga
    12721 tcagtaatag tgatgtatag agatttaacg aacggatctt atgactgtat gtatcaaaat
    12781 aaatcaacag catattttca atcaaatgcg tcaaacgact tgtttttccg ccgcgaaaat
    12841 gaatgaattg tgtatgttcc cctttttctt ttgatgcatt tatcaaaaaa gaagaaagta
    12901 gattatttgt gcttgccaaa tgattcaata tctctgtaga taaggtttct tcttttaata
    12961 agatgttgat taaaatatcc tcttgccctg tgtattcgat tctttgagta gcttctttat
    13021 caatgatcac cacgtcactt tcttccatct ctatcctttc tccattaata atttgtaaac
    13081 atgtaccgct atacatataa ttgatttcaa caaaatcatg tgtatgctcg ggaacttccg
    13141 catatcgacg gtgtttactg atatgaatat ttccctgttg aaatagatcc cctcggtgga
    13201 tttttggcgg tgtctgaaga tggtaagcta agtttaaatc attgatattc attccttgtt
    13261 cacgctgcag agtttcgatt gattcttcgt tacgcaaaaa aaatgtctaa ttcagctagt
    13321 tccaattgac tccctccttt ttgtaagcgg tttctttcgc ttattagttc acgctgtact
    13381 gctattatat gcaaagctat ttttggtttc ataaagactt tctatggttg ggacatgaac
    13441 ttcctgtgat tccgctattg agagaataac cacttcatac tatatttttg ataagcgctt
    13501 acaaaaatga aaggaacatg cttatgaata aaaagatgat gaaattttct ctgctgtcag
    13561 tctctcttat tttgacttct gctggtgcag tcacgtctgc aattcccagt atgtcagcta
    13621 cttatgccac gcgttcttta tctgctgttg aattattaac gactgctccc tcttttatgg
    13681 tcactatttt tgttttgatt agtagtttta ttgctaggaa aatcggacaa aaacaaactg
    13741 tgatcatcgg attagtgatt gcatcgattt gtggtatcct ccccctcttc tcacaaagtt
    13801 acagtattgt cttagcttca agagctggac taggtattgg ctttggattg atcaattctt
    13861 tggcagtcag catgattgct gccttttatc acggagatga acgagcctct atgattggtt
    13921 ttcaaagtgc atttcaagga tttggtgcag ctttaatgac atttgttgca ggacagctag
    13981 tacagttcgg ttggcaatat acctttttag tctacgccat cagcttacct attcttgtct
    14041 tgtttgtttt gtttgttcct acacctgaaa caactgaact tcaatcgcat ggcacagccc
    14101 caacaagaca agtaatcaaa acgaatccta aaatgattag ttatggtatt tttctcttgc
    14161 tggtcatcgt ggtatataat gctgtatcga ttaaattagc cacagtcctg acgacttatt
    14221 ctctaggaaa cgaaactaat gcagcgaata tcttaacaat catgcaattg gcaagtatgg
    14281 ctgccggagt ttgttttggc tggcttcaga caaaagcaca tcgctatatg cttacacttt
    14341 ctttactact gatgggaatc ggctttgtat tgattgccac tgtgataaac ctgtatgtga
    14401 ttgggtttgg tgcgatccta acaggaattt ctttttcgtt attcattcct tacttattca
    14461 accaagtaag tatccaagcg cccaagtacg cggagagttt caatacttca atcttattgg
    14521 ttggcgctaa tttaggtact ttcattgcac catatggttt gctctttctc tcttttgctt
    14581 ctcttgggag taaaacactt gctgttttcg tcaatggcag tatcttgctg ttgattagcg
    14641 cgcttattag ccttctagta gtacacagga cgaatagaaa gacagtgata agagtagatg
    14701 aagaaataaa agaacaattg acaacaaaat aaatttgatg gaggtcgtgt aaaatgacaa
    14761 atgaaaaaca taaagataga tggctttggt atcctggaga ctttgagatc cgccatggac
    14821 tgctacaaaa tttccaacgg gaagaacgag gttttgactg gccagcgtac tggtacatgg
    14881 atgattgcca tcggaacgtc aagtttaaga gatattactt tcttgatcaa ccttccatgt
    14941 ttaaagtgac gatccaagga gttgggtatg tagaaattaa tggacaaaaa catccatgtg
    15001 gaaaatggct gacttgtcca gctggtaaag caaaaattcg tatctttgta ggacatacat
    15061 cagggctacc agcgatgttt atcgagggag acgaagtaaa atcagatatt ggctggacag
    15121 caagtaattt tattgaagaa tatccagctg gctggagtcc gctttatgtc gatatcgcaa
    15181 aagatccaaa tcaaatctat tatcaaaaag aatgcgtcca tccagtcact gaaacggaga
    15241 ttggcggagg aatcttattc gattttgggc gagcagtgaa tggctgtgta gaactaatat
    15301 ctctggatga ccatatcgaa tctatcactc tatgttatgg agagtccgat gtagaagcta
    15361 tggatatcga ttattgctac tataagcaaa taggaatgac aagaaaaatg aaagctcgta
    15421 aacgcgcttt tcgctatttg tttataccag aggtttctac tggaatggtt caacttcaag
    15481 tttttcatga atttttatct ctttcgaaac aagctgcttt ttcaagcgat tcttctttac
    15541 tgaatcagat ctggtcagta tcagaagaag ccttcaagtt atgtagtgat ttgtttttta
    15601 tcgacggtat caaacgagat cgctggattt ggtctggaga tgcgtatcaa tcattcatga
    15661 tcaatcaata tctttttttt gacgaggaaa tcaataaacg aacgatatta gcattaagag
    15721 gacaaaatga aatcaagcag catatgaata ctatcgttga ctattcgatc ttgtggttga
    15781 ttggtatcga aaaccactat atgatgacga aagactatga atttttacgc atcgtctacc
    15841 ctaagatgca atcattaatg agatacttga tggagcaaac gaatgaatta gggtttattt
    15901 atgggagagc aaaagattgg atatttattg attggtctga aatggataaa gaaggaacgc
    15961 ttgctgcaga acaagtctta ttactgaaag cctatcattc catgatcact tgcggagata
    16021 tcttagctga aacatatgga gagaacgaaa attatcatac tcatctctat caagaaaaat
    16081 atcaactatt gaaacaaaac ctatttgact acttttggga tgaagaactt ggcgctttta
    16141 tcgattgcta tgaatctggg agaagaaatg tgacgcgtca tgcgaatatt ttcgctgttt
    16201 tattcgattt tgctaacaaa gaccaacagc aatcgatctt aaagaatgtc ttattgaatg
    16261 acactatcac acagattact actccatatt tcaaattcta tgaacaagat gctttatgca
    16321 aactcggaca gacgaatatc gtctaccaaa cgattcttga ttattgggga gggatgttat
    16381 ctcatgatgc ggtaactttc tgggaagaat acgaccctac tcaaacagga aatgaaaagt
    16441 acagtatgta tggagatcct tatggaaaaa gcttatgcca tgcatgggga gcaagcccaa
    16501 tctatctttt aggacgctat tttatcggtt tgtatccaac aaagccaggt tatgaagaat
    16561 ttatgataca acctaatcta gattcatttg aaacactgaa ttgtacgcta cctatcaaag
    16621 atggaaagat ttcgcttgaa aaaacaaaag ataagatcgt gattacttct gatagaacag
    16681 gcggaacagt gaaaatgaat ggtaaaagtt atcctcttct agcaaaacag ccacttgtct
    16741 taacaagcta ttcaaaaata aatgcataaa acaaaaaact gcttgcgaca tatcagaaga
    16801 ctttaaatct tcttctgata ttgtccaagc aatttttatt ttgaagtttg cttaattctg
    16861 ttctttagaa acaatgtttg ttctttttcc ggcaaaaaga aagctagata atacgacaag
    16921 taaaaagaaa gcgatgattc caactgtcaa ggctatttga ccgtattctc ctagtttccc
    16981 aagtacaagt cctggtacta gataatcagt atcggcaaat gtagaagaag cgattttaag
    17041 atctcctaat actggaagga taaataatgg cagccaacta atcaataagc tattgaaagc
    17101 agaacctaat accgcccctc ttctaccgcc agtcgagttg ccgaagacac cagaagcagc
    17161 tccgcagaag aaatgtccta ctaccccagg aatgataact gtagtttgca agcctatcat
    17221 agcaaacatg gatagtgttc ctacaaagaa gctaacaaaa aagccaatta atacagcatt
    17281 aggtgcatat ggaaaaacga taggaacatc taatgctggt ttagaatcgg gtacgagttt
    17341 tttagcaatc ccttggaatg ctggaacgat ttctgccaac accattcgaa ccccttgaag
    17401 gacgataaca aacccagctg tgaatgttcc agcttggatc agtgcaaaga ttacagcgtt
    17461 gtctccattg cttagttctc tttcaacaaa tccaggacca gctaacaaag caagtgcgac
    17521 atatacgatc gacatcaaga gcatgatcga tacagtagaa tctcgcaaaa agctgaaact
    17581 tttaggaatc tttatgtcct ctgtagaacg gtctttgttt ccaaaaaact ttccgatcca
    17641 tccactagaa gcataaccga tatttccggt atgccctaac gcaacttgat tgtttccagt
    17701 gatgttcttc ataaacggtt gacaaagagc aggcgtaata gttaatagtg ttccttcgaa
    17761 gaccccgcct aataagatca tccacaaatt tgcagtaaac cccgcgctta ctaaaatgac
    17821 tgctgttaga caagaaacat aaagcattgc ttgacctgta agaaaaatga atttatatct
    17881 tgtgaatcta gcaagtaaaa tattcacgat catccctact agcatgatca aagcagtagg
    17941 tgtaccgtat tgttgcaaag caatcgccac tactgcttca ttgctaggaa ctactccttg
    18001 agtatgcaga gctgtttgga acatcgaagc aaaaggggtt agtgaattac tgattaaacc
    18061 agcaccgccg atcagtacta ggaatccgac aaatgttttg atagttcctt ggatcacttc
    18121 tgaaaatttc ttcttctgaa gaacgagacc aagcagtgca atcaaagaaa cgaggatgga
    18181 gggctgactg acgattgaca caaacaaatt caacaattta tccattgata gttcctccct
    18241 tgaatcattt ttattctttt gacaagatct tcgttacttt ttcttttact tcttcgctgt
    18301 caatgatcga ttgcaaaggt acgagctttt catcaggtat agaagttagc gtatctttca
    18361 aagaatgctc aatgaagaaa taatcagcca tatcgctaga tacacttcca acatccgtat
    18421 gacttacttc aaactcgtcc acatctgctc caagatctgc aagtgcttgt ttgatgttca
    18481 tctctaccat aaaacttgtt cctaatccac tttgacatac tgcaaaaatt ttcatatcat
    18541 tcgtctcctt ttcttatgat cgctaatatt tcttcttttg ttgatgcgtg taataaatct
    18601 tgaagatttt gtttattaga aagtagcttt gttaaatttg ccaaagcccg aagatgtgcc
    18661 tcattatcga tagcagctaa acagatgaac aaactaatgg gatgggctgg attatcaagc
    18721 agatccacag gttgttgaag tttcagcaaa gacatcccta cttcgtttac gccatcttct
    18781 ggacgagcat gaggtaatgc gatgtgatcg ccaatatgga taaacgcacc atactgctcc
    18841 acgcgctcga tcatagcttt gatataactt tcttctattt tattttctga taatagcggc
    18901 tgtgcggcaa atgtgattgc ttcttgccag ttttttggtt gatccgataa ttggatcatt
    18961 tcttctgtta ataattcaga tagcatagga cgttgatcct ccttcttttc taaaagtttg
    19021 ttcattttac gatttaatac ttgatagagc ttttcttcgt ctacgccttc ttttaattcg
    19081 atataaggca gtagcgccga caacaattct tgggcagaag gcattgaaaa tcctggtatc
    19141 agccaatctc tttgtacttg attgatcagc tgattttttt ccaagtcagt catgattgga
    19201 tgcagaacat agagagactt tttcttatca gtaagtgtga gaggtacagt agaaaaaata
    19261 atatcgtaag aagtttcgtc aacctcgtgt aagcggtcag ctgaattagt ctctgtaaaa
    19321 aagatcatcg ggaataattg ctgaagttca ctttttaaga tcaatgaaga gctaatgcca
    19381 cttggacaga cgatcacggc tcttattttt ctatttcttt cttctgcgtc cgcttttctg
    19441 atctctccgc caaatagtat agtgaaaaaa ccaatctctt cttcagggat gctcttccct
    19501 attcgtcttt ctaacggaag taatgctttt cttgtcattt cgtagatgga agcatattga
    19561 tgcttaattt gatcgatcat cacattaggt aaataaaaag aataggaaat acgaaaatag
    19621 gcagggacca agtgataaaa gacattcatc aataattcac gaaacgaagc aaattctacg
    19681 gccatcagga attccatgcg atggatgact tctgaagaac attccagcaa aaaatcaagt
    19741 gcaggctcct ggacatctcc ttcaacgatc gatgctaagc aaagagagaa aaatataatc
    19801 tccgaatttt gatgttcgga atagccaagg ccagtcaata cttgtcgact aatgtcagtg
    19861 actgcaagag aagccaacag ttcagcatct tttaccagtt ccatggatgt ttttccaatt
    19921 cgaatggttg tcaaactcaa ataataagct aattcatcca ttcgatttgg tgcgaatcga
    19981 agatctgata gtgaaatcgt tttatctagc aaatctctaa ctttggcgta ataatcaatg
    20041 gaaagggttg cggttaaata cgtgagccca aatcttccag caagtgactg catcaaacga
    20101 gcagtgcgat tttttgcttc tcttcttaat attgcttctg accctagcag cctaaaacca
    20161 gttttcctag tatacgacag ctgacaatct tccacttcta attcatttct tatctttttg
    20221 atatctgaca ggactgtccc tttagaaacc tgaagaaaat cttgaaaatg aaaaacagaa
    20281 acagacgttg cagtcgaata aaccatcaaa taaagaagat ctcttcgctc ttgttcggta
    20341 tacacagctt caaatcgagt aatatccaaa aatttttctg cccagtcgat tgctcggaat
    20401 ttctttatac ggatacgggt atcatccaca tattcggcaa aaggagttaa ttgtttgatc
    20461 gcctcgcttg tatttacttc gatgatctct gctgcttttt ctagactgat ttctcttggt
    20521 gttttcagga gataactaat tttgtagttc acagcgctgt tcacctccta cttatattct
    20581 agtatggtag cgcttttaaa tcgaggggtg tttggtacaa cttacagttg gatttttttt
    20641 acgactgtac cgaacgattt ctatcgaatg gatacagaaa aaaagcaggt gaccaaatgt
    20701 ctcctgcttt tatgaattga tttcgtccga tcaatgatga tcatgtttat tttttgaggt
    20761 cagttcttca aatttttctt tgacatcttc aaccgctttt tcgatatctt tttcaaagtg
    20821 attgggctca ttaggctttg tttcctcttc tacagaattt gaaccagata aagctgtttc
    20881 tttattttct gtttcaccag agtttgtgcc agctaatgat tcttctttgt cttctgtttc
    20941 accagaatta gttcctgcta aagccacttc ttcttctgtt ttaggggcca ttgaacctct
    21001 taatcgtttg tgtttttcac cgtcataatt tgtcatgttg gttcctccta gtagttctat
    21061 actttttcat cgtacaataa gacagtttat gcgtcaaaaa acaaacccga ttcttacaaa
    21121 tatgtcatat ttttccttct gattcttgaa tgcttttgat tccttcttcc aaaattttca
    21181 tttgtaagat tgtttcttca tctttgatga ctttttctgc gccattaact aatgtctcgt
    21241 aaatcccttc gtagacacgg ctgtaatcac caacctcgga aattactttt tcttcatgat
    21301 aactcccttg ttcatctata taggtcaata caccataatg ttcgggcaaa tcgataccaa
    21361 agtcttcatg atcaggcatg taaaacattt tcagatgttc ttcttgtcga tcttttgttt
    21421 gtttcacgaa catccctttt tttccgtaaa cgacgaaact tggacgttct ttgatgcgga
    21481 aataactgga ttttatcgaa attttcatat ttccatagaa aaaatccaga tcgaagtaat
    21541 cattcattcg tcctttccct aaaagttgac gtacatcata gctgatatca tctggttcgc
    21601 cgaaataaga aagaacttga tctactgtat gacaagcatg tccatataaa tagctgttcg
    21661 cagtagaaaa ttcatgcgta ttttctggta cttccggtct gaaataatca taatgcattt
    21721 ctacttctaa aatatcccct aattttccgc tttcgattac tttttggact gtcaagaagt
    21781 cagaatcgaa ccgtctgttt tggtaacatt ggataaatag acctttttct tttgctaatg
    21841 caaataactc ttctgcttcc tttgacgttt ctgcaaaagg tttctctact agtacattct
    21901 taccatgttc gagtgccatt tttccatatt cataatgaaa ttgactaggt gtagtgatga
    21961 caactaattg gatctcagga tcatcccaaa gatcagacag ctgatcagta tattcgatgt
    22021 cttcgaatgt tttccacact ggttcagatg gggaaaaaat ttttttgata ttgattttgt
    22081 tcgtaagttt tcttgaaaaa ggcaaatgat agcgatttgt actctttcca ttgccaagat
    22141 aagcgattgt aagcatgagt ggtgcctcct tttattgatg ttttcagtat atcctagaaa
    22201 agcgcagaaa gtatttataa tagctattct ggtaaaaaag ttcagaaaaa cacttgttat
    22261 cattcggttt ggtgaaatta atgttcaaag taaggataaa aatcaaaaag atagtagcgg
    22321 aaccaagtgt ttatcagtaa gatagaattt ggaggtcaga tcatgcttat tgaagaaaaa
    22381 ctaacaaaac aagagttgtt taccacgaca gagaaacgga ttgtcgatta catccgtagg
    22441 aatatcgaag ctgcagtcta catgacgatt gaagaattag caaaagctac gtatacttcc
    22501 cattcagcta tcattcgttt atgcaaaaaa atgggattca gcggatttaa agaattccgt
    22561 ttcgagctgg ggcgggaagt tcatcaattg attgctcagt tcaatcaaac gattgatcct
    22621 aattttcctt tttcaagtga agatagcact cagcaaattg caaagaaaat ggcggattta
    22681 tcgatccagt caataaaaaa agcacaattg cagattgaac atgaagattt agatcaaatc
    22741 ggtaaagtat tgaacaaggc acagcgaatc tttctttttg caaaaggtga ttctcaaatc
    22801 acggcaagga aattccagaa taaaatggtc aagttgaata agtttttgat catggctgaa
    22861 gaatacagtg attcttcttg gaatgcagcc aatttgacta gcgaggattg cgccattttt
    22921 attagctaca gcggtcgcat ccatcattat gaacgaataa tgacctattt gaagcatgta
    22981 gaggccccta ccttgctgat taccggaaat cagcattcag aaatggccaa acaggctgat
    23041 atgtgtcttg ttatatcgca ggaggaatat gattttgcta aagtagcgac tttctcctct
    23101 caaattgcct tcgattacgt attaaatacg ttattctcag tgatatattc tcaaaatttt
    23161 gaagagaata tccgcaactt gaaaaacaaa caagaattga tgcaaaaagg ccttcttaaa
    23221 gaatatcgga aaacttaaga aaagatcctc atttagtaat aagaaagata gtgtttgata
    23281 ggctctcttt gatatcatca taaaaacagg ctgaagtttt ctttttcaaa cctcagcctg
    23341 tttgtttacg gaacgattcg aatagatata ttatagaaat gaggaatagc taacttctgt
    23401 ttcttatttt gaacgattga cgaaaaagat atataagaag gaggaaaatc agtatacatg
    23461 cagctaacaa tccatacagg aaaaatcgtt tgttctcgga tactttctgt acttcttttt
    23521 gaacttcttt tgcatgataa ggaacccggt gccctctgac aagtaagcga tgactgttga
    23581 ccatataagg tgtacaagtt aggagtgtca cgaaatcctg ccctttttcg attctcagat
    23641 cttttgtatc agtcggttct accgtcttga tctgatcgac ttgataagcg agtgtccgtc
    23701 cattgatttc gatatagaaa gaatcaccta aagtcagttt cggtaagtct gtgaacaact
    23761 ttgcttgagg cagtcctcga tggctggaaa taacggcatg tgtattttct ccccccgtag
    23821 gataagacgt tccttccaat aatgaggcac ctttttctag cagcacagta ttcgtttcat
    23881 caaaaattgg caaatggaca ttgatctcag ggatcgtcaa aataccgatc gtatgtttct
    23941 caaaataggt tctatccttt ttcgcaggtt cttttttctt agtaaaggga tctgcacctg
    24001 gatttccacc ttcttttgct aattgctggt ttttctttgt catgttttct tggattttag
    24061 ccatgacttc ttcattttct ttgaccgctt gttgctgata atgagagatg atctgctgat
    24121 ccagataatt attcagcgcg tcgctaacaa atggataagc tagtatccct attcctgaga
    24181 gaagcaagaa aagcatcagc agatctagaa gtttcctttt ctttggtttc atttgtgttc
    24241 tccttgtgat gactgtttga taataaaaga aaaaggagca tttgcgtaat ccgctgctcc
    24301 tttttccaat tcttgcaaaa agactaaatc tgactgtgct tgcgtctagc aaagtacagt
    24361 ccagcaatca gtagaaggac tactcctgca ccgatataca catagattcc cttaccgcct
    24421 gttgaaggaa gtgtaccttt gtgtttattt ggtatttttt caggagaaat caactgtcct
    24481 gctgttacat aagattgttc atcgatagta aatgctacac ggtttgttaa tggaacatat
    24541 ttttctggcg ctttcgtttc ttccagatag tacgtgccat attttagacc tgtcacatcg
    24601 attaaaccgt tacttgtggt tgtaaaaacc gttgctgatt ctttcgccga tacccagctg
    24661 acggcttttg tggatgggtc gatcgataaa tatttcgctg tgtcactatc ttgatcacga
    24721 acgacgaatt ctgctccagc aagtgtttgg tctgatgtaa cgtcaccatc tactttaaca
    24781 aatcgtttgc ccccagtaac gacatcgact gacggtggtg tttgatcatt tgtatgcccg
    24841 ttatcgacat ttgcttggtt agaaaatcct ttggttggat ctgctttttc gttcaaatgc
    24901 atatagtaaa cgaatttcaa tgtaccgcca ggagttaatg aaggaatata attcggatca
    24961 actgaaaccg tgaatccgtc tgtttgctca gtgacagaat aatttactgg gtcgatttct
    25021 ttatttccat catataaggc ataagcatac gttcctgaag aatcattatc aaatgttaaa
    25081 gcagcgtcat gagtatcgat aagtttgaat gttgtgtact tgttttgcgt tccttcttta
    25141 tcagcgatac ctaatgggat attgacagaa atctcatatt gaattttttc accgattgcg
    25201 acatcttttc cattcaattg aggtgttgtt ttatcaactt tagacgtatc atttttgatg
    25261 gtcttttcta ctggtgtttg gctatttgcc aggatctcaa aaggcgtgat tgtttgcttt
    25321 tcaatcattt ccgcattatc aggagctttt acttcttcta aattatattt tccaacttct
    25381 aaatgattaa cgatcaactg gcctttttca atagatgcct cggcaaagtc attgttgccg
    25441 atgtcataag aatgaccagt aatgaaatgt ttggctttgg tttgatcagt tgtccaagtg
    25501 tacaatccat ctgtgacact ttggatgtat tttttgacgc ttggtgttcc ttcttcttta
    25561 gaaataataa attctgctcc atttagtgct tcgttttcgg cagtaccgat ttttgtaact
    25621 ttcaacgttc catcattacc gactgtattt ttagggtaga gatggatagt atctagttct
    25681 tctgtcccgt atttataaga gccatctgct tgtttgatca tctcatatac agggaaagct
    25741 aaaaccatgt ttgcggcagc tgacactccg tcttttggtt cttctttgat cgtgtagact
    25801 gcatctttcc cattttgttt tttaggtaaa gataaagtga catttccatc agcatctgtc
    25861 gttcctgaag caactggtgt accaggagtc aaagactgga ctgcttgttt tgctgcatcc
    25921 acggacgctc ctttatctcg ttgcgcataa aattcttgag tgacgttata aactgaaaat
    25981 gaaatatcgg ctaatccttg gtattgatcg aattcgctca tttctttccc gctgttttgg
    26041 attaaaggat cgggtaaatc agtcattttc tttttatgaa ggatgacttg agctgctgtc
    26101 tcctctgcaa acactttttt tgcgccgaag ctgtttgtga gtaatggtaa aataaggaaa
    26161 aggactccta acataacgtt tattttttta tgatttttca ttttttcact cctgttcttt
    26221 ttttgataaa caaccagatt gcaaagcttg cgaataccat accaacaacg cctaaaagtg
    26281 tatttttcgt ttcgtttgtt tttggaagaa atggacggct attttctttt ttattgacta
    26341 ctttcaatat actgtccgcc tctttatcct cagaaagaaa agttgaaatg gtaaacggaa
    26401 tttctgtttc acttaaaata taaccagaag gtgcttcgat ctcttttaat cgataacttc
    26461 ctgttttcaa cccggaaatt gaaaaagcgc catttttatc ggaaatcagg tgaagcgcat
    26521 ctgattcgtt ctttgtccac ttgtatccgt tggctgtttg ctggaggtaa tttcctgctt
    26581 tgtttttaat aaggaatact gcgccagcta atcgtttatc tggtttattt gtctcgattt
    26641 tgacaaattg cttactccct gtatatacag agactttctt tgtactgaca ccaaaaccaa
    26701 aatccagtgt tccgttgttg ttgatttcct tgttcgcctg tgctgtactg cttagctgca
    26761 tctgataaga aatggtcagt ttttttccag catatttttc caacgaaggg atcgaaaata
    26821 aaacatcaaa tccgtgaggt ttcttgtgta tgacaaagcc ttctgtcagc ttttctccat
    26881 tcgatgaaat cgttaaacta ttaggtaaaa acgttaatgc ttcatccgca ctatctgaca
    26941 attcgaactt ttgatagtca aggatattta caggaattgt cgtatgcaag gaataagtga
    27001 ttttttcacc aatcgtaaaa tcatttctag gctcttctaa taccttctca aaaggtggat
    27061 cagggtagtc gttttcttca tttttaggat acaaatggat agttgaaagt ttttgattgt
    27121 tttgtccatg tacaggaaga acaactacca tattctctgc cttttctttg acgacttctg
    27181 gtactttgga ttcaatgaaa agatacgctt tatctctttt ttcttgatct ttagcggcca
    27241 gagaaaaaga agcgatacca tcttcgttgt taagagttgt agttgttgct tctgcggtaa
    27301 acataccgga agacgcaccg ttttttgcga tctctgcttg tgcttcttct accgttttgc
    27361 ccttttcccg tagatggtaa aaagaatctg tgacatcata aacttggaat gtgacaccat
    27421 ttaatcctcg atacgtttgt aataaagctt tttcttgtcc gtcatttgga tgatttttcg
    27481 gcagttgccc gtttgggaaa agcaatttgt gtaaagtaat ctgaaccatt tctgtttctg
    27541 tttctgttgc tacctgagta aaagctggtt taaatagtaa caagaagaga cacatactaa
    27601 gccaaccaag ttttttcata tttagctgcc ccctctttct tttttcaaaa aaagatacca
    27661 aatagaaaac gcacaaccaa tcatccctac tagatagatt cctaaacggc caattcctcc
    27721 cgtttcaggt aatggtactt ttgcctgatt cgtgatgtct aaagaaatct ggttgttttt
    27781 ggctcctggt gacagaacag attcatgatc ttgtccatcc acttgaattg acccatcttc
    27841 gtgtataact atagtaactg gctcttttag accttggtat ccttctggtg taaaagtttc
    27901 ggtcagcgta taagttccag gttttaaatt ttcgaataga aaggtatctg tttcttgtcc
    27961 atcttttggc gattctaagt ccatttctgg tccctgcagt ctgaattttg ctccttttaa
    28021 tgtctgtccg ttgtcttctt ttttgtgtac cgttagatca aacgctttta gtcgattttg
    28081 atgagtgagc gtccatacat tatttgtcat ctcggtattt tttcccgtgt aaatgatttt
    28141 tccatattta tcgatttgga attcataatt tcccggcgaa gtatcatatc cggcaggacc
    28201 agctgtttca acgactcgat atttaccagg tgtgagtgaa tcaaaactgg caagaccttt
    28261 ttcattcgtt gtttggctgt caattggctg ataagtacca tttgcttctt ttttctgtag
    28321 ggaaaatgct gctcctttaa gatttatctc tttgtccgtc ccttgcatcg catacttacg
    28381 tactgctaca ggaacttcaa caaaaggatt ttcaatagtc aactggatcg tatcatcgga
    28441 agtagtgact gtttttccat caatggttac cgtaccatca gaagcgatct tgatttccca
    28501 agtagtcttt ttgcttaatc catgcccttc tggagctttt gtttctgtca gcgtataggt
    28561 catttctttt tgcaatttga cattttctgg aagagaatag gttccgtcgc catgatctgt
    28621 tagtaaagta tcaatagaat ctcctgttaa tttgaaaaca gcgccaataa gatccttttc
    28681 acctgtagag gaatttttcg ttattttcaa gtttaacggt gtgaattgtt tagtattttt
    28741 ccatgtcatt gcatctattt gttgagaatc gtatcctggt acaggtaatt ctttgattgt
    28801 ttggtaactg aatgcttgac cttgattatt gtattgaggt agtgataata tctcttgata
    28861 actttctccg ctatttgcag ataatttgtc aatgtctgca cgttcccacg tatttgttgt
    28921 atctttagct ggtttaatga ttcgaatata tccgtttttc caagctgcag catttgtcgt
    28981 atgttcccgt tgaatctcaa aagtaacttg atctggacga tcagctagat tgttgtcaaa
    29041 ttcttcccat aactttttga tgtgaagact gactccggga gctttagcag atggtatacc
    29101 gaattcagct aattcattgg tatcaatgtt tggctggaaa gttgtcctgc cgttcatttg
    29161 ataccagaaa tttggatgga agtcctcatt ttctgtttgg attctcactt ggtaatggat
    29221 ttggatttct tggtcttttc ctaaatagat ctgattgctc ttgatggtat ttccttctat
    29281 ggaaatagat ggagtgaccg ttgtaggact tgtccccaca ctcttgactg aaagtgtacc
    29341 aggctgataa atgaatggtt ctgcgattgg atcatttatt tgtccattgc ttacagttgc
    29401 tgagatctgt acagcttttt tggctaggta ttcagagata tctgttgcat gatcagctga
    29461 ttcatagtaa agatcgcctt tttcatctga tgaaaccatt tgtcgcatac gagactctac
    29521 ttctgctttt gagagaccag ctgccggatc gctttgaagt tggatgccaa gaccatgtat
    29581 ttcgattcct cgttctttga gtgccatcgc ttctccgatg gttgcgataa acgtactgtc
    29641 gattcttctg gatagattgt tttggtcagg tgcatcatag attcttgaga ttagagaagt
    29701 atttcccggc cgatcttgcg tattagaaaa ctgagttccg taataattgc tgcttgattg
    29761 tgcgtgtacc cgctgtactt tataggaaaa tgttggtaca ccatccgtca gcaaaacgat
    29821 cactttttta tgtccatttg gaacggatag catgcttcct gcatctctta gtgctttttg
    29881 tgtaaaagta ccaccatttg tccgtgaagg tgtaatggat tttacttgat ttttcactga
    29941 atcaaatgaa cccatctgta ctgcaccgtt actgtagcta tatccttcgc ttgagtagcc
    30001 gacatatccc atattgattt tgtctgtgat accgctatct gctaaagtat cgacaaaacg
    30061 atcgacacca atctttactt caccgatccg attattgtcg ttcatacttc ctgaccagtc
    30121 tacgaccaat acgagatcaa gaggcgtgat atctttttgt acatttccac gagcattcaa
    30181 ataaacatca aacaatccgg gtgtacttgt ttcctttgca tactttcgta tcgcatagtc
    30241 tgcttgatta ccggttcctc catattcgat atacgaatgg gtccgatcat taggatctcc
    30301 attccaagaa tttataccat cccattgatt tgttccgttt ttattgcctt gatgatcaag
    30361 aacatttgta tttcctgtag gttgccaact ggctttagga taagtgccct gatcatctgt
    30421 tgtatattct gtaggaatcg tttgattaga tggcacactc acagctggca aggataatgt
    30481 aggcaatgta aatgggctga cagaattttc gttttctttt gatgattctt cttctatttc
    30541 gtctggcttt ggtactgaca catctgtatc tttcttattt tctgtctcat caataatgtc
    30601 atattcttta ttatcgacga tcagcttgtt tgcctggctg tggtaaagtg ctggatcgat
    30661 tggaaaactc agatcgatag tttgtttagt gtttgatgag atttccaacg taattttccc
    30721 gctatttacc tgataagcat agccatctcc ttcttttctt tccacatcac ttaagtaatt
    30781 ttcgactaga ccaatttctt tttctatctt ttcagcactg gtgttattcg catttagctt
    30841 gatgttcagt gctttttttc cagactgatc cgaaatgact tcagctgaaa ttgtttctaa
    30901 aactgttgga tcatctgtag tgtctgctat tgcagataat ggcacaaagt ttgataaact
    30961 caatattatc agcatgaaaa taactttcag tttcttccct gtggtcgtca tttttcccct
    31021 cctttttctt tttttctgtt ttgacgtgaa tagtgaaaat tattaaaata aacaggcgtt
    31081 acataatttt atttatttta atatgataat tattatacga agggcgctaa agggaatcac
    31141 accaattttc ataccaattg gtttcattta tgaagttgat tccttcgatt aatgagcgtt
    31201 tcattgaaag aaaagggttg agggagaaaa acatatgatc aggttgttgg aaggaaacta
    31261 tagaaagatg gaaaaaatca ttcgaattct gtccatttct gacaagtgga tgactaaaaa
    31321 agaacttgcc aaacgaattg gtagttcaga atctacattt gtaaggtata tcgaagagat
    31381 caaaatccgc tggggaacgg atgtaacgat tcaatcttca caaaaattgg ggtatcgtct
    31441 tgaacatttg aatgtaccag cttatttaaa tgttctgatg gaaatgtcgc aaagttctac
    31501 aaacagtcgt ttattaaatg agattattgt caatccgggt aaaacgattg agtattattg
    31561 tgaaaaaatt tccatcagcc ggtcttcttt tacacgtaag ttgaaacaat gcaatcaaat
    31621 tttagaaagc tatttattaa aagtgatcgt tgaccaaggt tttcagttaa ctagccttaa
    31681 aagtgagctc cagttgcgta tctttgttac ctttttcttt ttaagttact acggaagacg
    31741 cacgttgcca tttccaatcg aaaaaaagaa gatcaaagaa attatggtca agaataattg
    31801 tcagatgaat ttgtttcagg aagaaagccc atatgagcaa tctttcttta ttatgtattt
    31861 tgttgtgcat ctcatgagag aatcccaagg aactccattt gaatggaaag ctggagactc
    31921 ttatgtacag ttgataaata tcgataaaaa agacttctta atcttgaaaa atctcttagg
    31981 aaaattgaag tacagcagct atataaaagt agtgaactat tttgtcaata cgattttttc
    32041 agaattttcg gagaaagaaa aaaatgaaat cagtgagcag atacgaaaaa atatgtccta
    32101 ctgttcgttt tcatccgctg attgcaaaga aaaaaacgaa gaatatgttg ttcaattatt
    32161 aacgcaaatt tattttttct cccgtatttt cccatacgat acgactcatt tgacgatccg
    32221 tgcaacttac tttgcacagc agatgcaaca ccgccagata cgtctatatg ctggatttcg
    32281 tgcagaactt caattttatt ccactctact gaatcagaat ctgatttatt atttatctag
    32341 ctatatcttt tggatgctta tcggtaatcc tgaaattcac cattatactt ctgataaaaa
    32401 aatactgatt atcagcgact taagtcttcg acatagtcaa tatattgaag aatatatcag
    32461 tgatattctt gctgtgcata aaattcactc tgagacaact gctattactg aagatcagct
    32521 gtcgaaatac aatcttctcg agtatgatct gatcgttacg aatcaaccca ttttgaatgc
    32581 ccatgttcct catatattga ttgatgatag tgtgtcattc gcaaatgaag aagaactcat
    32641 ccgcttattc gagttatgaa taatcaaaaa acagctatgt ataaaccacc ctgataaaaa
    32701 tttcaggaca aatacacata gctgtttctt tttattgtat tccttcagca atccaacgag
    32761 atttatagcg aaagtctttt aacaactctt cttttgtcca attatttgca atgagatccg
    32821 tcaaagtgtt cattacgagg gtcatggaaa agtataggaa actaactgct tcttccgacg
    32881 attgaatgga gaaatgattg attcttaata attccagcca tttttcgttc attggagaat
    32941 cagccgatag ttctctacgt ttggttgtct gctgatcatt tcgctgggtt aacaagtata
    33001 acctttgcca atagatactt tcgtgatcta agtcgcagca ccactctaaa tatttttcga
    33061 tccccaaaaa gaaatgttgt ttgttttcgc taatgaattt taagatatct tgatggacta
    33121 tgtgagaact gcttttgatc gtatacaaat aagcatcttc caaatcttga aaatatttat
    33181 aaaaagcacc gcgcgacatc cccatcttgt caacgatttc tgagactttg acttggctga
    33241 tgtgctgtga gcaaaatatc tccagtaata ggtcatcgat tctctgtttc tttgcgttcg
    33301 ataaattgaa aaaagtttct tttggcatcc acatctctcc tttatctctg attatacgtg
    33361 gatagccctt cattgtcatg aaggattcat tccttctttt tctcttcttc tgtcaagtac
    33421 ccatcttcca ttcgataaac gcgatcactc cattgaatca tacggacatc atgagtaacc
    33481 ataatagtcg ctttttgttt ctcatgagct tctttaacta gtaatttgac gacttcatat
    33541 gcatgatctg tatccaaact agctgttggt tcgtctgcta agatcaagct tggctcatta
    33601 tataaagcgc gagcaattgc cactctctgt ctttctccac cagaaaggtc tttaggataa
    33661 ctatttttaa gtgactggat atctaaagat tgcagcaagg aatcgatttt tgttgaatct
    33721 tctttttttg aagtaacttg gtcaactagt tcaaattgtt cctttaccgt taaaaaagga
    33781 atcaaattag agctttggag aataaatcct atttctttaa agcgtaaatc tgctcgtttt
    33841 ttttctggaa gctcagttag tgagtgaccg ttgatcacta tttctccgga agtcggtgtt
    33901 tgcaatcctc ctgaaatggt aaggaaagta cttttacctg aaccagaagg accaatgatg
    33961 ctgacgaatt ctccttcctt tacataaaaa tcaattgctt tcaaagctga gacctttgta
    34021 tgaccagaac caaatgtttt ggtaactttt ttcatcgtta atattttttt catttttatt
    34081 aacctcctat tgctgtaatt gggtctactt tggttatcgt acgtatcgaa aacaatccgc
    34141 ctagcattgc gacaatgatc aaaatcccac tatatagcaa ccattgtgac caaaaaacag
    34201 caaaaggcat cgcgcttggt aaaatcagac tagtcaaata agcaaacaaa agagcaagca
    34261 gaacgcctac caccccaaca ataaaggact gtgctactaa agatttagcg atgaagaaat
    34321 ttttgatccc ttgtgctttc attactccaa aaatagcagt cttctgaagt gtcatcacgt
    34381 acatgaaaat accgaccacg gcagcaacca ctaagaacaa aaagtatatc atcgcattta
    34441 aggtcatatt ttgggcagaa tagccaggaa tactttcaat gaatgtccca atagttaata
    34501 actgtagacc cttcgatgct ttttctttcg aaattttagc tgaatccttt attacgatcc
    34561 cattgatcgg ctgttcttct tcagaagcaa acggctgttg tccatacttc aaagcagtcc
    34621 acgtatctag ggacgcatag atgacgggag aaactgtgta ataagtttca ggaaagatac
    34681 cgacaatcgt caaaggatcg tcgtaactgc caattttgat cgtatctcca attttatagc
    34741 ctgaatcagc cagattttga gagatgatga tttcattctt tgttttaaat tcatgccctt
    34801 tcgtgagttt tggtaataaa aatgcttctt tcgttgtgcc gaaaactgta acattttctt
    34861 tgttttttcc tttgattgct ccgctgtaca atccgattgg tgctttctct cctccttcaa
    34921 tgtatttcag atctcctctt gttaattgtg aagctgcaaa tacttgattt gcatcctccg
    34981 acaaaacaat ctcttgtgcg tcccaatcat cgattgcttt tttaaactct tctgaaagtc
    35041 cattcgctag tcctgacaac atgaatacga catacgcaat caagaacata ataccgacga
    35101 tcaagccata tcgtaattta gaatagcgaa tttctttgat agctagaaac atttgttttt
    35161 cctccctatg atagattgat agtgacaaaa tgtcacttgt tgaatagtgt aactctaaag
    35221 tgacaatttg tcacttgtgt tgtttttttc ttatcaataa attgtctaag acatctttcg
    35281 ataaaacctt aacatgagtc ataaaaaatt tatttaagcc ttatttatgc tttccatgat
    35341 aaactaaagt gaccaaatca atgaggtggg aaaatgatta aactattagt agtagaagac
    35401 gataaagtat tatccaataa tataaaagaa atactcgctg caatcggcga gataacacaa
    35461 gtttatgatg gtagtgaagg actgttcgag ttggaaagtg gagtttatga tcttgcaatc
    35521 ttggatttga tgatgccgga aatgaatgga tatgaagtgt tagcaaaaat acggaaagaa
    35581 aaaatacaga ctccagtatt gattttgact gcaaaagata gtttggaaga taagattgaa
    35641 ggatttgaac gaggtgcaga tgattatcta acaaaacctt tctatcgaga agaactgatc
    35701 atgcgcgtga aagcattatt gaaacgctcg ctaggtctct ttgatgaaaa tgttctgaag
    35761 tataaggata tcagttgtga tttaaaaagc aatgaagtct tgtataaaga acaagttttg
    35821 cccatacaag gaaaagagtt tgaattgctc gtttattttt tacaaaataa gggaatcatt
    35881 ttgacaaaag agcagatatt tgaccggatc tggggatttg attctgatac gacgattaca
    35941 gttattgaag tttatatgag caacttacga aaacatctgc gaagtactgg attggataaa
    36001 gaaatcaaaa ccttacgtaa tgtcggttat atactgcaaa gggtgtgatg caatgaatgg
    36061 agatattaca cgaaagcaac gtagtcgctt ttttgcgaca aatgtagcag catttgcttt
    36121 tatctttttt cttttgggat tcattacttt acagatatta aaccaatctg catacagaga
    36181 aacagatctg tcattagaga aaataaattt tgattctcga acagtacaat tagagataca
    36241 aagatatcag caaggcgatc cctttttaaa cccgactcaa acggaacaaa acagaacaaa
    36301 catggaacag ccattaatgg aaccatcaaa tgaccgtttt aacactcaag tgatcttgtg
    36361 gtctaaaaat ggtgagatat tgaataaagc agctattggt gggcgtttca accaaatcaa
    36421 agaattaaaa atggatacga aaaatctgaa taccatccaa aatattgaat taaatgaaga
    36481 cagtggctca tctgccctct ctttccgttc gattacgaaa aaagcggaga cgaatcaaga
    36541 tggcgttgcc tacatccaaa ttttagaaaa tacaaatcaa atcaagaatt cattagcgac
    36601 ttttcgcacg attatgattt tgtgtatgat tgttttttgg attctctcta ttggtatcag
    36661 ttattacttg tctagtctaa gcatgcgccc tattattctt tcttggagaa gacaaaaaga
    36721 atttgttgag aatgcttctc atgaattgcg cacaccgtta acgattattc aaaatagttt
    36781 ggaacatctt tttaccaagc ctaatcatac tattattgaa gaatccgaaa gcatcgctca
    36841 agcattgtca gagacgaggc gcctcactgg attgacttcg gatttgctga caatcgctcg
    36901 gaatgattct gatcagcagc tgctttcaaa gcaaatgatc aatacacaag aatatatcga
    36961 acaacttgtt aaaccatttc aagagatggc caccatagat ggaaaagagt ttattctcca
    37021 taacgatgca acattagaag taccaattga tgaaaaaaaa atccatcaag ttttggttat
    37081 tttgctggat aatgcattaa aatatacgaa tccagaagat aagatcattt tggattcatc
    37141 tgttaaccat aaagaatggc tgattcacgt aaagaatact ggcccttcta tcagtgaaga
    37201 agatcaagca aggatttttg atcgatttta tcgggaagat caatctcggg cgaaagagac
    37261 tggcggatac gggcttggct tggcaattgc aaaacaggta atcgaacagc atcatggaca
    37321 gatttctgta tccaattatc ttccacaagg agtcgatttt aaagtccaat tgccgttgaa
    37381 gcctaaaaaa taatgcttat ccctaaaaaa gggctgtgac aaaaatcttg tcacagccct
    37441 tttttgttgc gaataaacgg tgttccagaa gtagcttctt cggaaataag ccgaaatttc
    37501 tttaagctga ccacttctgt cacaacctct ttagcttacg cttacgattt tttattgcgg
    37561 tcttcaatgt gtacatcacc gcttgtgtca atatccaatt cttctcggct aacatcttct
    37621 gtcacttttt caacatcttc atgttcttct ttatgaatcc caacttcttc acgaataact
    37681 gtatgtttgc ttacatctac ttgctcttct ttgattggga tagtaatcgt gtcatcttcc
    37741 aatttttcgt ctgttccctg tgaagattga tctgttactg gtttgcgttc gatgacgatt
    37801 tcttcacgtt tgaccggtac ttctaccgtt tcagtatcgt tgaccacatg tttgtggatg
    37861 tcgacttctc cagttgtcac atcatgtgta tttacatcta atttttcttc ttttagttga
    37921 attgtatcat catctagatt tggtttgcga tcgatgtctt cagtcttgct tgtacccatt
    37981 gtatcagtct cgccaggtac gtccatcgga tcagttcctg gtgtcatatt caatggatcc
    38041 gttgtatttt gaaagcctgt cgtgccacct acgtccattg gatctgttcc agtgccagtt
    38101 tctaatccag tccccattgt gcttgctggg ctaacagtat cttgtgtatc cattgtatct
    38161 tctgttgttt ctggctgacg atagcctttt actgtgatga caaattttcc atcagaaata
    38221 tctcctctat attgatataa aggatcattt tctggtgtag ccgtctcaga atcataggta
    38281 tcaaaagaaa aagtatcttt tattttttcc cataaagaac ggtcttcttc accatccatc
    38341 cgattttcat ctgtttcaac atctatacca gacaatccgt caaatcctag tctagatgct
    38401 gcttcatcag tagtataaat aacgatatca tctcgttcat acccttcgtt acgcaaccgt
    38461 tcaattactg ataatgcttc ttccctcgta ctatagcttc cgatgaccgt taaatttttc
    38521 tcttccatgt aaattcctcc tagcaaatag atttatgatt ggtatattgt tacttataaa
    38581 tttattctat aggagacgat tgttttctac aaatatttag attggaattt gattaaaaca
    38641 atttaattga aatttgaaaa catttatgtt aatgaaagtc atattctaat aaaatgtcat
    38701 ttgtttctat atgaattttt atgaaaaatt tcatataatt tccactcgtt gtgatggttt
    38761 aatttatcca atccatcaat aagcaaacaa cttatataaa aaaggattaa ttctcaatat
    38821 aattgctcct accatagaat aaatcttcat gtaaagtaat gaagtaccaa ctatttctaa
    38881 tacttcttta agaattatcc caacaatatc gttagacaaa ccattattga ataaatggag
    38941 agccaatcga ttctgaaaaa atgttttcta atttttcgga aataaaagaa agagcctcct
    39001 gccattagaa cgaaccaaat ccatttcatt gctcatgaag taaccacata gctaaaaaga
    39061 ggataaatca attaaaagat caaaagaatg actgcactaa taaaataact aaaaatgtat
    39121 cttcttactt catatctttt agctagtact tagttaaaaa tttgcttcct aagatcaaga
    39181 caaactgtct atcttcattt gatgaaatgc ggtaaaatat agaaaatgaa cactattgga
    39241 gggaatttgt aatggacagc aaaactagaa aacaactgca agaaaagtta aagcaacgta
    39301 cacacttgct cccttccgtc tttcaacagt ttttagaaga aaatcgttct tccctttcat
    39361 taggcagtcg ctatgaatac gcaaaagatt ttcatctgtt tactgattat ttgagaaaag
    39421 tattttctga agaagtggat gatcagctga ttatccattt agaaaaacaa gattatcaga
    39481 atttcttagc taaaatctat cgacatactc gttcgttcca aactacagcg aaccaagaaa
    39541 cggagcaatt gtttgaaaat agctattacg ggatttcaag gaagcaatat tcattaaatc
    39601 attttttacg atttttgtat caaaaaggac tgattgaaga agagatttct cttttgggta
    39661 caagtttacc ggaaacaacc aaagcagctc cgcgatatat cgatgcagaa cttttcaaag
    39721 attttgagca tttgtttatc ccgattgaag gctttcaaac aagcagagaa gctagctttg
    39781 aagaaaagaa tagaccgagg aaccttgcaa ttactgccat tcttctgtat tgcggattaa
    39841 agatccatga agtagtagaa cttaaacgta aagatgtatc tttgaccaag cagattctta
    39901 atctgaatag aaaagaaaac agactgaata aagtaccaat accaaaagaa gcgatgccat
    39961 ttctggagaa ctattttaag ttaacagcac aaaatacgga cgaaaattct tttgtttttc
    40021 gttcctcaca tgatcagcaa atttctcctc ggactattcg ccaaattttg agcaaaatta
    40081 cagtatataa aaacgtatcg ccagaactat gcagaaaaac atatcgttat tatgcagaac
    40141 tatatttaga tgatgctgac gcggtaaatt atttatgtgg taatcgatac ctctcatccc
    40201 attcttttca agatatctgg gaaaagatgg ttgatttttc ttatcacgaa ttagcggcat
    40261 tcgttcgggt ttcttccata taaaacaaat gtatgatctt tttttcacaa taaactatgt
    40321 tattatataa aggattatgt tacgattatc ttgaatttgt atattactta acaaaagata
    40381 atggagtgtg aatgatggag accataacgt attccccttt gaacttattt acgaattttc
    40441 aagaagctgc agctaacttt tccgagaccc cgattatctt tgatgagcca ctttcagctt
    40501 tcccagaatt aggacttgaa acaacttaca aaaaatgctg cgaaagtgtg ttgaaacggg
    40561 cttatcaatt ggctcatctt ggagtgaaat ccggagacaa agttattatt tataagagtt
    40621 ccgcttttga cacatacctt ctagctgttt ctgtgtctta ccttggtgca gtgcctgtca
    40681 tgacttctta tcatctacca acaacaacaa tggaagtatt tatcgatcgt ttagaagacc
    40741 ctttcatttt atttgatgat gagacaaaaa agcgagtgag agaaatttca aatggaacaa
    40801 aatcaaaaca gattcc
//
LOCUS       DAKCAA010000021        40424 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000021 DAKCAA010000000
VERSION     DAKCAA010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.021"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            212..604
                     /locus_tag="OUE31_001202"
     CDS             212..604
                     /locus_tag="OUE31_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCU0222221.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="OUE31_001203"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="OUE31_001203"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HCU0222222.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3164..4774
                     /locus_tag="OUE31_001204"
     CDS             3164..4774
                     /locus_tag="OUE31_001204"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HCU0222223.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5066..5935
                     /locus_tag="OUE31_001205"
     CDS             5066..5935
                     /locus_tag="OUE31_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HCU0222224.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6100..7371
                     /locus_tag="OUE31_001206"
     CDS             6100..7371
                     /locus_tag="OUE31_001206"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCU0222225.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7368..8663
                     /gene="rho"
                     /locus_tag="OUE31_001207"
     CDS             7368..8663
                     /gene="rho"
                     /locus_tag="OUE31_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HCU0222226.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8762..9025
                     /locus_tag="OUE31_001208"
     CDS             8762..9025
                     /locus_tag="OUE31_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HCU0222227.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9470..9919
                     /locus_tag="OUE31_001209"
     CDS             9470..9919
                     /locus_tag="OUE31_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0222228.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9976..11394
                     /locus_tag="OUE31_001210"
     CDS             9976..11394
                     /locus_tag="OUE31_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCU0222229.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11394..12254
                     /locus_tag="OUE31_001211"
     CDS             11394..12254
                     /locus_tag="OUE31_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HCU0222230.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12428..13201
                     /locus_tag="OUE31_001212"
     CDS             12428..13201
                     /locus_tag="OUE31_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCU0222231.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13348..13713
                     /locus_tag="OUE31_001213"
     CDS             13348..13713
                     /locus_tag="OUE31_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HCU0222232.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13861..15069)
                     /locus_tag="OUE31_001214"
     CDS             complement(13861..15069)
                     /locus_tag="OUE31_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0222233.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15088..15366)
                     /locus_tag="OUE31_001215"
     CDS             complement(15088..15366)
                     /locus_tag="OUE31_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222234.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15520..16215
                     /locus_tag="OUE31_001216"
     CDS             15520..16215
                     /locus_tag="OUE31_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCU0222235.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16657..17454)
                     /locus_tag="OUE31_001217"
     CDS             complement(16657..17454)
                     /locus_tag="OUE31_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HCU0222236.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17451..18635)
                     /locus_tag="OUE31_001218"
     CDS             complement(17451..18635)
                     /locus_tag="OUE31_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCU0222237.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18660..19907)
                     /locus_tag="OUE31_001219"
     CDS             complement(18660..19907)
                     /locus_tag="OUE31_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCU0222238.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20122..21867
                     /gene="dnaX"
                     /locus_tag="OUE31_001220"
     CDS             20122..21867
                     /gene="dnaX"
                     /locus_tag="OUE31_001220"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HCU0222239.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21887..22201
                     /locus_tag="OUE31_001221"
     CDS             21887..22201
                     /locus_tag="OUE31_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HCU0222240.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22226..22822
                     /gene="recR"
                     /locus_tag="OUE31_001222"
     CDS             22226..22822
                     /gene="recR"
                     /locus_tag="OUE31_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HCU0222241.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22886..23530
                     /locus_tag="OUE31_001223"
     CDS             22886..23530
                     /locus_tag="OUE31_001223"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HCU0222242.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23545..23874
                     /locus_tag="OUE31_001224"
     CDS             23545..23874
                     /locus_tag="OUE31_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HCU0222243.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23888..24826
                     /gene="holB"
                     /locus_tag="OUE31_001225"
     CDS             23888..24826
                     /gene="holB"
                     /locus_tag="OUE31_001225"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HCU0222244.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24862..25686
                     /locus_tag="OUE31_001226"
     CDS             24862..25686
                     /locus_tag="OUE31_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HCU0222245.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25679..26026
                     /locus_tag="OUE31_001227"
     CDS             25679..26026
                     /locus_tag="OUE31_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HCU0222246.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26095..26967
                     /gene="rsmI"
                     /locus_tag="OUE31_001228"
     CDS             26095..26967
                     /gene="rsmI"
                     /locus_tag="OUE31_001228"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HCU0222247.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27076..28197
                     /gene="dinB"
                     /locus_tag="OUE31_001229"
     CDS             27076..28197
                     /gene="dinB"
                     /locus_tag="OUE31_001229"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HCU0222248.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="OUE31_001230"
     CDS             complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="OUE31_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HCU0222249.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="OUE31_001231"
     CDS             complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="OUE31_001231"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HCU0222250.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31656..32450
                     /locus_tag="OUE31_001232"
     CDS             31656..32450
                     /locus_tag="OUE31_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222251.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32440..34482
                     /locus_tag="OUE31_001233"
     CDS             32440..34482
                     /locus_tag="OUE31_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222252.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34763..34912
                     /locus_tag="OUE31_001234"
     CDS             34763..34912
                     /locus_tag="OUE31_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HCU0222253.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34923..36437
                     /gene="dltA"
                     /locus_tag="OUE31_001235"
     CDS             34923..36437
                     /gene="dltA"
                     /locus_tag="OUE31_001235"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HCU0222254.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36434..37639
                     /gene="dltB"
                     /locus_tag="OUE31_001236"
     CDS             36434..37639
                     /gene="dltB"
                     /locus_tag="OUE31_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HCU0222255.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37684..37917
                     /gene="dltC"
                     /locus_tag="OUE31_001237"
     CDS             37684..37917
                     /gene="dltC"
                     /locus_tag="OUE31_001237"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HCU0222256.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37920..39188
                     /gene="dltD"
                     /locus_tag="OUE31_001238"
     CDS             37920..39188
                     /gene="dltD"
                     /locus_tag="OUE31_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HCU0222257.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39329..40411
                     /locus_tag="OUE31_001239"
     CDS             39329..40411
                     /locus_tag="OUE31_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HCU0222258.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
BASE COUNT        13016 a         7088 c         8462 g        11858 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttaatcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga atttcggctc cctattctta ttgaagaata gggagctttg tttattgtct
     3121 gagacttttc ctgcacataa attaaaaagg agtttttgaa cttatgacaa aatatatttt
     3181 tgtgaccggc ggtgtcgttt catcaatcgg aaaagggatt gttgcagctt ctttaggacg
     3241 cttattgaaa aaccgcggct taaaagtaac tatccaaaaa tttgatccat acatcaacgt
     3301 ggatccgggg acgatgagcc catatcagca cggagaagta ttcgtaacag atgatggtgc
     3361 tgaaacagat ttggatctgg gccactacga acgttttatt gacatcaatt tgaacaaata
     3421 ctccaacgtg acgacaggaa aaatctattc tgaagttttg cgtaaagaac gtaagggcga
     3481 atacttggga gcaactgttc aagttattcc tcatattaca aatgagatca aagaaaaaat
     3541 catgcgagca gctaaaatga ctgattcaga tgtgatcatt acagaagtag ggggaacagt
     3601 aggggatata gaatctttgc cattccttga agcacttcgt caaatgaaag cagatgtcgg
     3661 tacagataat gttatgtata tccatacaac attgattcct tacttgaaag ctgctggaga
     3721 aatgaaaact aaaccaacgc agcacagtgt aaaagagcta cgtggtttag gtatccaacc
     3781 gaatattttg gtggtacgta cagagcaacc tgtttctcaa agcgtgaaaa acaaattggc
     3841 acaattttgt gatgtcgaac cagaagcagt tatcgagtcg ccagatgtag atacacttta
     3901 ctccatccca ttagttttac aagcacaagg aatggatcaa attgtttgcg accatttaaa
     3961 actagataca ccagaagcag acatgacaga atggaaagaa ttagaagaac gtgtcttgaa
     4021 cttgaagaaa aaagtacgga ttgcgcttgt cggtaaatat gtcgagttac cagatgcata
     4081 tatctcagta gttgaagcat tgaaacattc tggtttcgcc tataattcag acatcgagat
     4141 cgattggatc aaagcacaag aattaacgag agaaaatgta gaagaacgtt tgaaagacgc
     4201 agatggaatc ttggttcctg gtggatttgg tgatcgcgga gtagaaggga aaatcgaagc
     4261 gattcgttat gctcgcgaaa atgacgttcc gtttttaggt atttgtcttg gtatgcagat
     4321 ggcttgtgtc gaatttgcac gtaacgtcgt tggattagaa gatgcgtcat cagctgaaac
     4381 gaatccagat acagcaaaca atattattga tttaatggct gatcaggaaa acatcgagaa
     4441 tttgggtgga actttacgcc ttggattata cccatgtaaa atcaaaaaag gaacgaagac
     4501 ggctgaagca tatgatggag ccgatgttgt gcaagaacgt caccgtcacc gctatgagtt
     4561 caataacaaa tatcgtcaat tgtttgaaga acaagggcta gtcttttcag gtgtctcacc
     4621 agataaccgt ttagtagaaa tcgtagagct gccagagaaa aaattctttg tgggatgcca
     4681 attccaccca gaattgattt ctcgtccaaa tcgcccgcaa aaattaatca aagcatttgt
     4741 cggagcatca ttagcagatc acgaaacaaa ataatttttg aacttgatag aaagagaaaa
     4801 gtagcaagag aaggggataa gcaattttct tgtcactttt ctctttttct gatttgttat
     4861 tatttgtagg aaaaaagata gaaagcaaaa gacttttttc gattaaagcg ctattggata
     4921 ttttattttt tgcaaaaaac ttcttgaaaa ttttcatttt cattgatttt agtagaaaac
     4981 taccgaaatg tttggtaaaa tagggtcgtt ggttaagaat tgtcttaaca aatttagttt
     5041 tacaaaactt aggaggaatt ttattatgcc agtagtatca ggagctgaat ttttaaaagc
     5101 tgctcgtaaa ggcggttacg ctgtcggcgg attcaacaca aacaacttgg aatggactca
     5161 agcaatcctt gaagcggctg aagcaaaaca agcaccagta cttatccaaa catcaatggg
     5221 tgcagctaaa tacatgggtg gttacaaaat ctgtaaagat ttaatcactg atttagttga
     5281 agcaatgaac atcactgttc cagttgctat ccacttagac catggtgatt acgaagctgc
     5341 tttggaatgt atcgaattag gctatacttc agtaatgttc gatggttcac atctaccatt
     5401 tgaagaaaac ttgaaattag ctaaagacgt tgttgaaaaa gcacatgcaa aaggtatctc
     5461 agttgaatgt gaagttggtt caatcggcgg agaagaagac ggaatcatcg gtaacggcga
     5521 attagctgat attgaagaat gcaaacaaat ggttgctaca ggtatcgact acttagcttg
     5581 cggtatcggt aacatccatg gtcaatatcc agaaaactgg aaaggattag cttttgacca
     5641 cttacaagca attgctgatg ctgtaggtcc agacatgcct ttagtattac atggcggatc
     5701 aggtattcct caagatcaaa tcgaaaaagc tatctcaatg ggtatctcaa aagtaaatgt
     5761 taacactgaa ttccaattat catttgctgc agctactcgt aaatatatcg aagctggtaa
     5821 agataaagaa ggtaaaggat tcgaccctcg taaattatta gctccaggta aagcagcaat
     5881 cgttgaagat gctaaatctc atatcgactg gttcggttca gctaacaaag cgtaagcatc
     5941 cacataacag atacgatata taggaatgga gaacgacttt tgaagtcgct ctccattctt
     6001 ttttacttaa aacggcagac catgctcgtt tctttttttt atctatgata aaatacaagc
     6061 atatccatga aaaaagatta ataaacaagg tggaaacaga tgaaaaaaat cgtaatcaaa
     6121 ggaaaccgac ctttagctgg tgaagtaacg atcagcggtg caaaaaatag tgcagtcgca
     6181 ttgattccag ctgcaatctt agctgattcc ccagtgatct tggaaggtgt gccggacata
     6241 caagatgttc attcattaat tgaaatttta gagatcatgg gcgcaactgt ccatttttcc
     6301 aacaacatac tagaaatcga tcctcgagaa gtcgtatcga ttccgatgcc gcacggaaaa
     6361 atcaatagtt tgcgtgcttc ttattatttt atgggaacac tgcttggtaa atttggcgaa
     6421 gcggtagtag gcctgccagg tggctgttat ttaggcccta gaccgattga cctacacgtc
     6481 aaaggatttg aagctctagg tgctgaagtg acaaatgaac atggtgccat gtatttacgg
     6541 acagaaaata aaggattgcg tggcaatcgg attttcatgg acgtggtttc agtcggagca
     6601 acgatcaatg tgatgttagc tgctgtaaaa gcaaaaggac agacagtaat tgaaaacgct
     6661 gcacgagaac cggaaatcat agatgtggca actttactga ataatatggg ggcaaaagtt
     6721 cgaggagcgg gtacagatgt gatccgtatc gaaggagtcg aaacattaca tggctgtcgg
     6781 catttcatga ttcctgaccg catcgaagca ggaacctatc tagcattagc agctgcagta
     6841 ggaaatggta tcaaagtgaa aaatgtgatc tttgaacatt tggaaagctt tatagcaaaa
     6901 ttgcaggaaa ttggtgtcca tatgaaaatc agcgaagatg aaatcgaagt ttacccctcg
     6961 aaagaattaa aacccgcaaa catcatgacc tatccttatc caggatttgc cacagatctg
     7021 cagcagccac ttactgcgtt actattgatg actacaggca cttcagaaat catcgatacg
     7081 atctatgcga aacgtgtgaa ccatgtgccg gaactagcac gaatgggcgc tgatattacc
     7141 gtggaaggaa atatgatcat cgtgaatggt ccaaataaac ttcacggcac agaagtcgtg
     7201 gcttctgatc ttcgggcagg tgcttgttta gtgattgctg gactattggc agaagggaca
     7261 acgacgattt acaatgtaga ttatatctta cgcggttatg atcatattat cgagaaacta
     7321 acagccttag gggcatcaat tgaaatgata gaggaagtgg gagctgaatg agcgattatt
     7381 tgacaatggc agaactagag aacaaaacgt taaaagaagt ttatagttat gccaaagaat
     7441 ttaaaattcc ttattacagt aagatgaata aaaaggaatt atctctagct gtgattcgtg
     7501 cacaagcaga gaaacaagga ttttattata tggaaggaat attggatatc gttggtcaag
     7561 atggttacgg ttttttacgg ccaatcaatt atggaccaag tgcagaagat atctatattt
     7621 ctgcctcaca aatcagacga ttcagtttga gaaatgggga caaagtggca ggaaaagccc
     7681 gtccacctaa agaatcggaa cgttattatg gtttgatgca cgtggaaagc gttaatggaa
     7741 aagatccgga agaagcaaaa gaacgtccgc attttccagc cttaacacct ctttatccgc
     7801 aaagacagct tcaactggaa acaacaccgc aaagactatc tacccgaatg atcgatatct
     7861 tttctccaat cggttttggt cagcgtggat tgatcgtcgc accgccaaaa gcagggaaaa
     7921 cttctgtatt aaaagaaatc gcaaatggta tcaccgaaaa ctatccggaa gtagaattaa
     7981 tcgttctact gattgatgaa cgaccggaag aagtaacgga tctagaacga agcgtgaaag
     8041 gcgacgtggt atcttctaca tttgatctgc agccgcaaaa ccatactcga gtttctgaat
     8101 tagtattgga acgcgcaatg cgtttagtcg aagataaacg agatgtcgtt atcttgatgg
     8161 atagtattac tagacttgct cgggcctata acttagtcgt tccaccaagc ggacgtacat
     8221 tgagtggcgg gattgaccca gccgcattgt ataaacctaa gaaatttttc ggggcagcaa
     8281 gaaacatcga agaaggtggc agtttgacga ttttagcgac cgctttagtc gatacaggaa
     8341 gccgtatgga tgacgtgatc tatgaagaat tcaaaggaac tggaaatcta gaattacaac
     8401 tttcacgtga attatctgaa cgtcggatct tcccagccat cgatatcaaa aaatcaggta
     8461 cccgaaaaga agaattattg atgccaagtg aagaattaga agaaatttgg aaacttcgaa
     8521 aaaatatgac tggagattca ttagaatata cggaacaact gatccgcttt ttgcgtaaaa
     8581 caaaaaacaa tcagcaattt ttcaaagaat ttcaagatgt ctcctttggt aaaaaaaatc
     8641 cgaccagaaa tctgaaaaga taattgcaac cttgactgaa acatgttaag atgttaatgt
     8701 tgtaaatcga caaatcaact ctggttcagc aaatggagca gggcaaagga gcgaaaaaat
     8761 catgaaagaa aacatccatc cagattacca cccagtagta ttcatggatt caacaactgg
     8821 tttcaaattc ttgtcaggtt caacaaaaac ttcacaagaa acagttgaat gggaagacgg
     8881 taatacatac ccagtcatcc gtgtcgaagt aacttctgac tcacatccat tctacactgg
     8941 acgtcaaaaa ttcacacaag cagacggacg tgtggaccgt ttcaacaaaa aatacggtct
     9001 caaagacgca aacgctgcgg aataataaaa acgctgataa ctcaacgttt agcagactat
     9061 ctgataggga tagtctgttt ttttatgttt tttgccaatt taaaacttcg tttgatgctg
     9121 aaaaagtcgt aggatcataa tgcacaaaac aatgaaaaac tagtatatag ttttaattat
     9181 ccacttgata aaaacacctt atattaacga aatgaagagg ggttatttcg aagtaaaaaa
     9241 ccatttacct aaaattagaa gctaagcttt cctttcaagg aaggcttttt gttttgttat
     9301 agacttgcga ttgtttgtga gctagatcgt tcattttaat gacttataca cgcggatgat
     9361 gggtcttttt cctctgttca ttcataatat tgaacggtac agctagcgat gctatactga
     9421 cctcagttcc aagaaaacgt taacattttt tgtgggggag aggtttttta tgaggtttga
     9481 tcaattgatc gcagaagaac tgattgtttt cgatccatcg atagattcaa aaggatcatt
     9541 atttgagcga ataggggatg tgttgaaaaa aacaaataag gtaagaaatg ttcaaaaagt
     9601 cgttaaggca ctattcaaac gagaggagga gatctccaca ggaatagaag atggatttgg
     9661 gattccccat gcaaaaagca aatatgtgac aaaaccagca ctgtgttttt ttcatacagc
     9721 caaattaacg gactatagcg ggatagatga aatgccaatt gaatatattt ttgccatcgt
     9781 agttcctgaa aaatcagcag atatgcatct agagattctc agcacactct ccagacgatt
     9841 gatgaatgca gattttagaa agggaataaa agaagccact acgccagcag atatcatcag
     9901 acagattagt caagaatgaa aatagtagag tctttgtccg agtatcgata gtgaagaaaa
     9961 aggaggaaaa taatcatgaa aatcgttggt gtaactgctt gcccgactgg aattgctcat
    10021 acttatatgt cggcagaaaa attagaagta acagcaagaa atctaaacca tcaagcaaaa
    10081 ttcgaaacac aaggtgtaaa aacagaaaat cagttatctg aacaagaaat caaagaggca
    10141 gatgcaatca ttcttgcagt agataaagaa atcgaattgg accgatttgc cgggaaaaaa
    10201 gtaaagcgtg tctctacaag ccgagcaatc aaagaaccgc aagtagtaat agacgaagca
    10261 ttgagagata ttggcgtatt cgttgtgtct aatgaaaaag aaccagctgc aaatgagaaa
    10321 aagccgacaa tctataatca tttcatgaat ggtgtgaatt acatgcttcc atttgtgatc
    10381 gcaggcggaa tcatcatcgc actgagtttt gcctttggga ttacagcggc tgatcccaac
    10441 tcagcagact ataatgtgtt agcagctgca ttttcaagga tcggaggaga tacagcgttt
    10501 gccatgatgg ttcctgcgtt aggcgcgggg attgctacat cgattgctgg aaaagcaggt
    10561 tttgccccag gaattgttgc cggattactg gcctctacag gtggttcagg ttttcttggc
    10621 ggaatgattg gtggcgtgct agcagggtat atctgtgatt ttctggcaaa taaaattagc
    10681 gtaaaaaaag aattttctgc tatttatcag ctgattgtcg tccccttttt atcgatctta
    10741 attattgggc ttttgatggt atttgtgatt gaacaaccga tcacatgggt gttggatgct
    10801 ttgacaaatt ggctgaatag cttgggaaat acatccgggc tattgttcgg attacttatc
    10861 gggatcatga tggcagctga tatgggtggg ccgatcaata aatcgacttc gactttctcg
    10921 atcggtttga tgtcagctgg agtaaatgca ccgattgctg cttgtatggc tgcaggaatg
    10981 acacctcccc taggtattgc tttagccact ttattattca aacataaatt taccaaagaa
    11041 gaacggactt caggtcaatc atgctggatt ttaggcgctt cgtatattac agaaggtgct
    11101 ataccgtttg cggtatctga cccgatccgc gtgataccta gtttgatgac aggttcagca
    11161 gtcgctgcag ggatttccat ggcagtagga gttacttcaa tggcacctca tggagggatt
    11221 tgggtgatgc taattccaaa tgttatgaac aatttaccta tgtatgtctt ggcaattgca
    11281 tcaggtacag tcactacagc ctttatgctt ggactattga aaaaaacagt gaaagagaaa
    11341 aaacaagaca agtggacgaa aaatgaaaat ctaacaaatg aggtggaagc gtaatgttat
    11401 atacaatgaa agagttattg aaagtggcta aagagaatca atttgcagta ccagccttca
    11461 atatttgcag ctatgatatg atgaaagcaa tcatcgaaga agcagagaga ttagaagcac
    11521 cagtaatctt agaaattcat cctgatgaaa tcgcctattt aagtgatgag tttgttgcgg
    11581 cagtaagagc ctatgcttat acaagtaaac tgccgatcgt tatccacttg gatcatggcg
    11641 gtacgataga agatgtctta cgggcgattc gaaacggcta ttcttccgtg atgatcgatg
    11701 cgtctttgaa atcattcgac gacaatgtac agattacgaa aaaagtggtt gcgttagctc
    11761 atgcggtaaa tgtctcagtg gaggctgagc ttggaacgat tgggaataat ggttctgctg
    11821 aaggaggtgc tgaaacaatc atttatacag atcctgatca agcgaagatt tttgtgaaag
    11881 aaacaggaat cgatacactt gctgtagcaa ttggaacagc gcatggcttg tatccgaaaa
    11941 acagaactcc aaaattaaat atcgacttac tgaaagaatt gaaccaacaa atcgatcttc
    12001 catttgtttt acatggcggt tcaggtaatc cggacgcaga agtcagcgaa gcagtaaaat
    12061 acggagttgc caaagtgaat ttgagctcag atcttaaaag cgtctttttc aatgctttga
    12121 gagaaatatt gagtgaaaat ccatcgatgt acgagccgaa tgcaatttat ccagcagcta
    12181 ataaaaaggt acaagaagtg gtcaaacata aaatggaaat tttgaacaca gtaggcaagg
    12241 ctagtttata ctaaaaataa aaatgtgtgg tcaagagggt atgacaatag tcttgtcata
    12301 ccctcttaac cacacacgat gttcagaagt agttttttcg aaaaatttct tcttatttct
    12361 cgaagccaat cacttctgtc acaacctctt ttttcctgtt actatataaa gtaaatgggg
    12421 tgattttatg ttgaatgaag tggagaatag acagcaggag attgtgaatt atctaaaaaa
    12481 caaccaattt gcaagagtca ccgatttgat cgagttagta aattatagcg aagccacgat
    12541 taaacgtgac cttgtttttc tggaaaaaag tggattgatc cgtagagttc gcggtggcgc
    12601 catgcttatt gacaatcgaa aaattgacgt gccttacctg atgaagatca ccaaattaga
    12661 agaagaaaca gaaaaacgta agattgcaga tacagcttct tctttgattc gagatgatat
    12721 ggtcttattc ttggattcca gtacaacctc tttacactta gtcagaaacc tagcaagatt
    12781 tgatggtttg cagatcatta cgaatggcat cgtcacagct gctatgttga gtgaatatac
    12841 aacggcaaaa gtatctgtat tgggaggggc aattgttccg aaacgagcaa caatcaacgg
    12901 ttcaaaagcc tataacgatg cattgtcata ttatgcggat ttagcgataa tgagttgtcg
    12961 cgggctagat ttcagccaag gagtaacaga aactcatgaa ggagaggcaa tggtcaaaaa
    13021 agcttttaga aaacaatcag accggcttgc cgttttagtt acacagcaaa aaattgcaca
    13081 taaattcatg catcaagcca ttgcttttca tgaaatcgat tatctggtga caagtaaaga
    13141 actgacaaaa gaacagtatg cgaaagtaaa ggaacaccat atcgaatgtc tgtacggata
    13201 aattattacg tgaatgttct aagtggcttc ctcattttta gataggacct tatctttgct
    13261 cgcttctctc agccgatggt ataataatga aaaggttatc ttgttagata atcttacttt
    13321 tttatccagg agaaaggagt gcagaaaatg aaacatgtga aggcgttggt agtgaaggca
    13381 atcatgatct gggcgattct gtgggtcgtg ctgacaggtt tatacggtgt tagctttatg
    13441 gattcaacga ttgttggggt aattattgta gtcatgatct atgtgctagg ggatctgttg
    13501 atcttacgta aagtagggaa catcgcagcg acgatcgcag atgctggttc agctgcagtt
    13561 atcttgtggc tctatctata ttttatgaat gatacagtcg atatttggat gaaagtattg
    13621 attcctgctc tattgatcgg tgtggcagaa tggttcttcc acaagtggtt gctaagtcaa
    13681 ggcatcgtac cagatgaacg gaaaatggaa taaatcaaca gttaaactat tcttatcgat
    13741 aaatgaaagc tttaaaaata aatagatgtt taattaagaa taatcataaa ctatttttac
    13801 tcaaaaaacc gctcagatta ttttcagatc tgaacggttt tttttatcta ttcatcaaga
    13861 tcaaatttca tttttcaatg attcaatcaa ttcgccctct gcttcatgac tatgttttcg
    13921 gccattaaca agatagagtg ctgtacatat caatggaatg actccggcaa tcacatacaa
    13981 tcctctaaat gaagtaagag attttagcat ccccatcaaa taaggaccaa cgcctaagcc
    14041 taggtctaaa ccaataaagt aggtagataa agcaatactg attcgatgtt cgcggacgat
    14101 ttttaaacaa acagcctgtc catttgacat aaacgtacca taacctaggc cgactaatgc
    14161 tccagagata agcaatgtca cactattcgt cgttacactc agtaaaaata atcctgctgt
    14221 taagaataaa tagctaggat acatcacgta ttgttctcct ttgacatcga aaatccttcc
    14281 agtcaatgga cgtgtaaatg tgatgaccaa agcatatacg acgaagaaaa atgacccagc
    14341 agcaactaag tggattactt ttgtataaga agataaaaat gataaaacac ttgaataaga
    14401 aagacccatc aaaaaggcaa ttcctgtaat gaaaagtgct ttcttttcaa taaaactatt
    14461 gatattccat gagcgaagag atattttttg ttcttcagat aatggaatat tttttacagg
    14521 aaagacaagg caggcaatcg taacaaagaa gaccagtaca attgaaaacc agataatgaa
    14581 acgaaaatca gtcatattca gcaaaatcat tcctaaaaat ggcccaacag cggcagctaa
    14641 actagtactt aatccataat aattgatgcc ttcccctttt ttagatgcag ggatatatgc
    14701 agtaacgata gcatttgtag ctgtagaaac tgtaccgtag ccgaatccat tcaagaatcg
    14761 aactaaatac aatgccccga tagttggcgt ataaagatat gctaatgttg aaaggagata
    14821 gaagatcgcg ccgcctctta aggtaaactt ccgaccaaat agttctaact gtttccccat
    14881 gaataagcgt gccagcaatg ttccgatgat atagatccca gaagcaaaac ctgcttggct
    14941 caagctggcg tgtaaggtgt cttgcgcaat gactgccatg atgaccatca acagataata
    15001 aatcaggtag acaataaaat tgatcaatgt gattccaata aaatatttat taaataattt
    15061 cttttccatg tatgttatac attcccctta agctgaatat gcttttaatt tttgtatttg
    15121 aacttctaca tcgtgataat tggatggata gcgatcaaca agttggcgaa taaataaatc
    15181 tcttgtagac ataaacagat ttaaaaattc ttcgcattcg tttgttggat tctcatccac
    15241 tgctttgatc aattcgatcg agttttgata cgcatcattt aaaaagacta aagaagcttt
    15301 catatcaaat cttgtttgat atgctgtttc taatcgatta atgattgtgt tcatccagta
    15361 attcatgttt tttccctcta ttcttaaaaa attttacttc tgcagtataa cgaataaaaa
    15421 aaaggaaaaa aatcgcataa gtgatggaaa aaggtactta acaaatgtta atatcattag
    15481 taaaatacct ttggacttta aaaagtttta aagtactgta tgatcttttt agatgaaagt
    15541 ttggatgggg gagcatcatt ggatagtaga gtcttaaagg aatatttgga taaaaatgat
    15601 tttccgatta tacgcaaagg atatcataaa tatttgacat tcgaagggat ggaagattcc
    15661 catacgtata tcttgaaaga gggaacggta aaagcaagtg ttatttcaaa tgatgggaga
    15721 gaatttaacc ttcgctatat caaagatctt gaaatcgtct ctcttttaaa agacgaatat
    15781 tcacaattca tcgattcgcc gtataatatt cgagttgaat cagaatatgc agagttttat
    15841 cgaatcaatc gtgtgcgctt ttggcaaaat atcaaccaag acccaaagct acaacactat
    15901 gtaaaagagt attaccgcta tcgtctgctt tattcgatga aaaaaatgca gcaaatgcta
    15961 ttaaacggaa agctgggagc tgtttgtacg caactttacg aattatatga tttattcggt
    16021 gtgcggacag aagaagggat gctgatcgat ttttcgatca cgaatgaaga aatcgccaaa
    16081 ttttgtggca tctcaactgc tagcagtgta aacagaattt taaaacaact gaaaaaagat
    16141 ggtattatca ccgttaaaga ccatcatatc gttattttga atatggactt gttagaagac
    16201 aatattatct tttgatgaac aaagaggttg tgaaatcagc gttttgacct gagtattaga
    16261 gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
    16321 agctgattga acaccgttta ccaagaggtt gtgagcctgc cgtttaactc tgagtcacaa
    16381 ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg tgaccgagga
    16441 gttggtagga gaacaccgtt taccaagagg ttgtgaaaaa gctgttctgc atcaagtaat
    16501 aagaagagcc aagtaaaaac agtctcttat gtttttaact tggctggact tatcaccgta
    16561 gatgtaagct tttgaacgcc gtttatttgc aacaaaaggg gctgtgacac gatttttgtc
    16621 acagcccttt ttttgcgaac attcatttag caatttttag aaacttctgc cgccaccgcc
    16681 aaaagtcccg ccaccgctag aatgggtagt acttccgcca ccgccgcttc caggaggtgg
    16741 gcttttgggg attcttcttg tcgtgacaaa agaatttgtc agacgatcgg ttttttcagt
    16801 taatttgata ctggattttt ctcggaatgg atatttgtag atgcctgatt tcaattgata
    16861 acgcgaaaca gtcacaaaat aaaagacaag actaaggata agagccaaaa caacagcaat
    16921 gatgatttct actgtcgtca aaaccttata gcgtgtaatt ttgccagttt cttcgtctac
    16981 acgataatgt cctcctggaa ctccgtcttc cacatatgtt gctgatttag acaggtaagc
    17041 ttttgcagca ttgtaatagg cagcatttgt catctgatca taaacatcat ctaagatcga
    17101 atcgattctg ctatcagtca aataatcgat catattacca gaagtcgaaa tgtagatttc
    17161 acgctgtccc atatctaata gcaatactga gccattttga tcatttccga ctgcgtctct
    17221 taagtaatta tcagcaaagt ctcttggttc ttctgaatta gatgtagtcg ttacgatcaa
    17281 gactcgtcct ttgatttttt cattcagctt ttctgcctgt tgttccaaag attggatttg
    17341 atctgttgtg aataacccag cctcatcatt taccgtagct gtatctgcat gagtagccac
    17401 cggccagcca acacttacta gcaaaagaaa gaataaaaaa aattttttca tcatatcaag
    17461 taacctccga tcagaaagag gatcgctagc ccagcgaaaa tcccaagagc ggtcagtccc
    17521 aattttttct ggctgatcgg caggacaccg ctgacctttc ctgtttgtcc attcattgcg
    17581 tagtagtaga cttttttact tgagtcattg cttcgataag taacaagcca taccggcagt
    17641 aatacgtaat tatttacttc gtttgtgatt gaagcagaag ttcgcacacc ggtcaatgtt
    17701 gtatatccat ttgcggtatc ttttaacagc ttctctgaat agtcttttaa ttcagattga
    17761 atctgtgatt tgattgcctc atattcgata tctctttttt ctgcttggaa cccggctaaa
    17821 tactggcttt taaaatcaat tgctttatct aacgggaaag gttgcacgcc ttcgaccatc
    17881 ttttgttgcg tattttttga taaggcattt tttactagtt ctttaaaaga aagcttgcct
    17941 gctcttgaaa cagcaaattg cttcgtttct gtgtattcga tgtcacctat ccgccatatg
    18001 cggataactg taccattcgc ctgcatggca ccatctactt cagcatctgt agcccaataa
    18061 gggaaataca cacctgtcaa cttatcgatt tgatccttat tgaaaaaagc tttgggaaca
    18121 aaccattttt tcttggtcca agcgagaaat ctgttgattg cttcttcttt ctcgacagca
    18181 aaaggaagta ctttatttgg caagaattct ccgcttaaac gtcccgatag tacgacggga
    18241 ttatggcagt agtaacaata agtcgcagca gttgtcgcat cagtcacgat ctctgcacca
    18301 cagttgggac aaagaaaaag atctatcgct gcggtattat ctgcagattc gtccgctgta
    18361 tctgaaaaac cgcctgcctc gtcaaccgct ttgcgctcgg cttcattcat atcggcaagc
    18421 tgttcttggg ctgtaaaagt aaaatcttcg gtaggtgaag gttcttcttt gctttcttcg
    18481 ccagccatac gcgcttcttt ttgcttttgc tcatattggc tgacttcttc ttctgtatag
    18541 atattcaggc agtattcgca atgaaatttt tggtctttgg gatcaaaagt caacggaccg
    18601 ccgcaattag gacatttatg tgtaagaaca tccatcagct gcacaccttt ctaaataaat
    18661 taattaacgg ggattccttt aaacggttta ccacagtttg gacagaattt agggatgccg
    18721 ttggaaagat ccacgatctc attgcattca ctgcatcgca tttgtagctt aggctgaacg
    18781 ttttctacag gtttggcagc tccgcagttg gaacagaatt ttccggaatt ttctgtcccg
    18841 caaactggac atgtccaagt atccgcattt ccttgtgcag tttgttgatt ttgtttttct
    18901 gcttgttgtt tgatttgttc ttggttattt tgagctgctt gagaaagata agaaccattt
    18961 gcattcattc ccatacctac acccataaag ccggtcattg ctcctgcttc attttttccg
    19021 gctgcttcca taccacgtgc aatggaacct tgcacgtatc cttcacgtac gctaggatca
    19081 cctagcatcg ccccttcgtt acgcatattg atcagtttca cagaatcatc ggtgtaagaa
    19141 atgctggcta cagccacaga aacaatctcc atcccacgta attcacgcca agaatcatcc
    19201 aatgcagtat ccatgtattt gcttaattcc aaactcttag atggtacata agaaatccgt
    19261 tgaccatctg cagacatctg attgattgct gattgtagcg ctgttaggaa ttcagctaaa
    19321 tactgctcat tgatatcatt gatttccact tgtgttttgt ttttagggat tgcgtttgta
    19381 taaaataaaa tcgggtcaac gacatgaata gaataagtgc catgtgcccg taagaataat
    19441 tctgcgttat agaaattgtc aaagtagttc aacggcgcgc ttgtaccgaa tttgattccc
    19501 tttatttctt ggagattgat ataaaaaact tgttgtttct gcggtgtgac gccgccaaat
    19561 ttgaatcggt caaaagtttc agcaattgct tctttcagtg ttccattgaa catggaagga
    19621 gctgcgtcat ttttaatggt gtaataacct tcctcagcgg tataatcgat gatttttcca
    19681 ccatcgacca aaagcatcat catgtttgga tagacatgga cgactgttcc gtctgttaaa
    19741 acatcttctg ttcctttacg attggagcca cgtttgtcat ctttgcggac tttgacacct
    19801 tttgtcatga ccgttgtatc actcatattg tctggttcga tgacttctag ccattgatct
    19861 gccagaccgc cgccaaccat acttgttgct gctttgataa gacccataaa aaattcctcc
    19921 tctgattcag ctagtgccaa acaattattg tttatttatt ataccatagg aagatgtgaa
    19981 acttctcgga ctagagacgg aattgaaatg gaaaattgcg tattgtttaa atacctgaaa
    20041 aagccgagaa ggatagtagt ttttttacct aatatcacgt ataataagag atagtgaatt
    20101 ttttaaaaaa gggggatcct tatggcatat caagcacttt atcgagtctg gcgttcgcag
    20161 cgtttcgaag acatcgttgg acaaaaagct gtgacacaga cactaaaaaa tgctattgtt
    20221 tcccacaaaa cctcacatgc ctacttgttt acaggaccca gaggaaccgg aaagacgagt
    20281 gcagcaaaga ttttcgcaaa agcaatcaac tgtccgaaca gtaaagacgg tgagccatgc
    20341 aacgaatgcg aaatgtgtcg atcaattact gctggtacgc aagaagatgt gatcgaaatc
    20401 gatgctgcca gcaataacgg agtcgaagaa atccgattta tccgtgatcg ggcaaattat
    20461 gcgcctacaa aggcagcgta caaagtgtac attattgatg aggtacatat gctttcaaca
    20521 ggagctttca atgccttgtt gaaaacattg gaagagccaa aagaaagtgt catattcatc
    20581 ttagcaacga ccgaacctca caaaatacca gctacgatca tttcacggac tcagcgattt
    20641 gattttaaac ggatcaatac ggcagatatt gtcgaacatc ttgaatttat cttgaaagaa
    20701 tcgactatca gctatgaacc agctgcattg aatgtgattg cccgttctgc agaaggcggg
    20761 atgcgggatg cattgagtat tcttgatcag gcaatctcgt ttagtgaagg aacaattact
    20821 ttagatgatg ccatgcaagt gacaggtagc ttaactgacg aaatgatgga cagttacttg
    20881 agtgcttgcg tgaaaaaaga agtaccagaa gcattggaaa cattgaacca aattctcgca
    20941 gccggcaaag aatcacgtcg ctttctagag gatatgttac aatactgccg tgacttgctg
    21001 atgtatcagc aagcacctaa cctagttgag gaacaatcga gtacgatcag aagtacattt
    21061 acagaattgg cacaaactgt ttcagcggat cagctgtttt caatgataaa gattttgagc
    21121 gatactcaaa atgaaattcg ttttaccaat agtgccgcta tttatttgga agtcgctaca
    21181 gtcaaacttg cacagctacc gtctgcttct gttccttcag cagatgtagc atttgcagat
    21241 gatcagatag taaaacagct acaacaagag attaaggaac taagaaacga aatcaaggaa
    21301 ctacgcagta atacaggaat tgagaataca aaagtacagc cggtacagca aacaaatcat
    21361 aaaaaacaga caagtaccta tcgtgtaccg acggaacgag tatataaagt tctgcgggaa
    21421 gcgacaagac agcatctgaa ccaagtaaaa gaagtatggg aagacttgct gatgagtcta
    21481 tctgtcactc agcgagcaat gcttaaagca agcgaaccag ttgcagctgg acctacagga
    21541 ctagtgattg cgtttgatta tgagattgtt tgtcaaagag cagcaaatga cgaagaattg
    21601 cagctttcgg tacacaacaa cttaagccga atgatcaaag attatgcgcc tgatcctgtt
    21661 tatattacaa gagaaagctg gccagaactt cgaagaaatt atttgacgca ggcacaagaa
    21721 gagggaacag aaaactcttt tgcttctgaa gactcagaag gagaaatcga gttgcttcct
    21781 caagaacaag aagtaccaga agaaacactt gtagtaaaag cagaggaact gtttggctcc
    21841 gaagctgtta cagtggtaga tgattaataa aaaggagtag ataattatga tgcgtggaat
    21901 gggcaatatg caaggcatga tgaaacaagt acaaaaaatg caaaaagaaa tggcagaagc
    21961 acaagagctg ctaaataaaa cagagtttac aggtaaagcc accaatgaat tggtcaaagc
    22021 ggtttttaca ggcgatcgtc gcatgaaaga tatccaaatc aatgaagaag tcgttgatcc
    22081 tgatgatatc gagatgcttc aggatcttgt cgtaatggca gtcaatgatg cgatcgcaca
    22141 aattgatgtg gaaactgaga aaaaattagg gaaatacgca aaaggtttgc caggatttta
    22201 gttttaaact gaaggagtaa tgaatatgca atatccagaa ccaattgcga aactgatcga
    22261 cagctacatg aaacttccag gaatcggtca gaaaacagcg acaagactcg ccttttatac
    22321 gatcgatatg aaagatgaag tagtaaatga atttgctaaa tctttgttaa gtgtaaaacg
    22381 cgatttgcat ttttgtagta tctgcggaaa catcacagaa gaagatccct gcgaaatatg
    22441 tagaaatcct tcacgtgatc gaagcgttat cctagtggtc gaagagccga aagatgtaat
    22501 ggcaatggaa aaaatgcgag aatatcacgg actttatcat gttctccatg gtgtgttatc
    22561 accgatggaa gggacaggtc cagaagacat caatatttct tctctgttgc agcggctgca
    22621 tgatgcagat gtaaaagaag tgattatcgc aacaaatgca acaacagagg gagaagcaac
    22681 agctatgtat ctctcacgtc tgatcaaacc cgcaggtatc aaagtgactc gtctagcaca
    22741 tggtctgtct gtaggctctg atatcgagta tgcagatgaa gttactttat tgaaagctgt
    22801 cgaaggaaga cgtgagttat aaatttctaa ttaagtgttt tttcagatac aatataaaag
    22861 cagcacaaga gatgggggca acaatgtgaa cggactattt attacaatcg aggggcctga
    22921 tggtgcagga aaaaccagca tcttgaatga actttaccct cttttgaaag aagtagcaaa
    22981 aacagaaatc attcaaacaa gagaaccagg aggcattccg attgctgaag agatccgagc
    23041 agtgatcctt gatccaaaaa atgatcggat ggatgaacgt acggaagcac tgctttatgc
    23101 agcagcaaga agacaacatc tagtcgaaaa ggttctgcct gctctggcaa aagggaaaat
    23161 cgttttatgc gatagatttg tcgacagttc tcttgcttat caaggtgcag gccgacgcat
    23221 cggcgttacc gagattgctc ggttgaatga gtttgctaca gaaggtacta cgccggattt
    23281 taccctttat cttgacgtag attcagacac cggattaaga agaatcaaga aaaacagaca
    23341 aaatcaaatc gaccgtttag attcggaagg tttggaattc caccagcgtg tacgtcatgc
    23401 ttacttaaag ctggcagaag agaatccgga aagaatccac aaagttgatg caagaaaaag
    23461 ctttgaagaa gtgctgcaaa caagttatca tacaattatt gaacagtatc cgcaattttt
    23521 tgaaaactag gaaggtgaac gtttatgaaa attattttag cgattatcca agacaaagac
    23581 agcaaccgtt tatcaaatga attgattgat gcaaatatcc gtgccacaaa actatcatcg
    23641 acaggcggct tccttaaggc tggaaacagt acgtttatcg tgggtattga agatgaccgt
    23701 gtagaagaag cattggaaat catcaaaaaa acgtgtgaat caagaaagca atttgtatct
    23761 acacctgtta cactggatat ttcgatggat gggggcgtcc cttatccagt agaagtagaa
    23821 gtaggcggtg ccacagtctt cgtcttacct gttgaaggat tccatcaatt ttaggaggag
    23881 ctgagctatg aatcaagaaa taaacttggc tcaaatgcaa ccgatcgtgt atcagcagct
    23941 tcaacggagt tttgagcatg ggcgtatcgc tcatgcttat ctttttgaag gggagaaagg
    24001 aacaggaaaa catgaagtag gtatatggct tgcacagcac ctgttctgta cccaaatgaa
    24061 agacaatctg ccttgtggaa aatgcaacaa ttgtcagcgg atcgaaaaga aagaacatcc
    24121 agatgttttg gttattgaac cggaaggaca aaccatcaaa gtcgatcaga tcagacgttt
    24181 gcagacggaa ttcagtcgca gcggttacga atcaagaaaa aaagtttttt tgatcaaaga
    24241 agctgaaaaa atgaatagca gtgcggcaaa cagtttgttg aaattcttgg aagagccccc
    24301 tggagatttt ttagcggtgt tagaaacaga tgcagtagga agaattctcc ctactattca
    24361 atctcgttgt caagttctgc attttcaaga actttcgaaa gaagcactga tccatcgatt
    24421 gcaagaagag cagattccat tggaaaaagc aaaacttttg gctttcttaa caaacagttt
    24481 aggaaaagca gttgaaatct ctcaagatga atggtttaat gatgctaagg acttgattta
    24541 tcaatggttc gtttacttgc aaaagcaaga tactcaagcc tttatctatg tccaaaaaaa
    24601 attggtaaaa tcatttaaag aaaaaacaca acagtttaca ggattatctg tcttgatgtt
    24661 ttattatcag gaagcacagc gtcaagcagt agcaaacggc gaatatggca aagtgaaaca
    24721 gataaaccag ataattgaac ggatattgat cgcagagcag aaactacgca gcaatgtcag
    24781 ttttcaggct gttgcggaac agttcgtttt gcatacgatt ttttagcttg ccgcaaagga
    24841 tgatgatcaa ggaggatgga aatggtagaa gtagtaggtg tccgatatag agatgcaggt
    24901 catatctatt attttgcacc aggagactct gaatatgttt atagtgacaa ggtattagtc
    24961 gaatctcagc aatccttaca tattgctact gttgtccttc ctaaaaaaga gattgatccc
    25021 aatgaccttc ctgaagctat ccgtccgatc ttgcataaag cgtcacaagc tgaattagaa
    25081 aaagacaaaa aaaacaaaaa agatgcttat gatgcattga aaatcgcaaa agaaaaagtg
    25141 cagttgcgtg agttggaaat gaaaatggtc aaagccgaat acacatttga tcgaaataaa
    25201 ttgatttttt ctttcacagc ggacgggcga attgacttta gagaattggt aaaagatctg
    25261 gccgctgtat ttcgtactcg tattgagctt cgacaaattg gtgtccgcga tgaagcaaag
    25321 ataataggcg gaattggtcc atgtgggcgt ccattatgct gttcttcttt tttaggcgat
    25381 ttcgtgcctg tatcaatcaa aatggcaaaa gatcaaagtt tatctttgaa tccaacaaaa
    25441 atttccggtt tatgcggacg cttgatgtgc tgtctgcaat atgagagcga agaatacgag
    25501 acagcgaaaa aagaactccc tgactttgga aaagtaattg ctacacctga tggtaaaggg
    25561 aaagtcgtag ggttgaatct gcttagccgt atcgttagta ttcggctgac tggacgggaa
    25621 aatcctgtcg aatatgaatg ggatgaattg aaagaattta tccaagtagg tgagatgaat
    25681 ggataagaga tcattatacg acggattgaa tcaattagaa tcagagttga gaaatacatt
    25741 aacagaactt gttgaaatga agcatgcttt gcatgagatc gtagaaaaaa atacaacttt
    25801 ggagatggaa aatcaacgtc tgcgggaaca cctgcgggaa ttgaaccaag ttgcacaagc
    25861 tccagctgaa aatgtgaagc aggaactttc taagtctcgt atgaatcttg aaaaaattta
    25921 tgaagaagga ttccatgtct gctacgattt atatggatca agaagggaca atgacgagcc
    25981 ttgtgcgttt tgtctagaag tgatctatcg cgaaagcggt cgatgaccaa taacaagagg
    26041 agactggagc ggagaaatac tgctccagtc tttttattaa ggagattgtg acagatgtat
    26101 aatcaaaaaa gtttcaaggg aaatccggta tatggggatt tatatcttgt accgacgcca
    26161 attggaaatt tagaagatat gagctacaga agtgttcgta tgctgcaaga atccgatctt
    26221 atcgcaagtg aggatacgcg taatacacaa aagttattga atcattttga aatccataca
    26281 ccccaaaaaa gtttacatga acataattat aaagaacgtg tccctcaatt gattgctttg
    26341 ttaaaagaag gaaaaacgat tgctcaagtc agtgacgcag gaatgccttc catcagcgat
    26401 cctggacatg agctagtttt agcctgcata aaagaaggga tttctgtgat ctctatccca
    26461 ggacctacag ctgggatgac ggctttgatt gcttcagggc tagtgcctca accattttta
    26521 ttttatggct tccttccacg taagaaaaaa gaacagaaag aaacattgaa aaagctaaaa
    26581 gaacagacag ttacgctgat tttttatgag tcaccttatc ggatcactgc tacattgacg
    26641 aatttcttag aaatttttgg aaatcgccaa gtcgttttgt gtcgggaatt gacaaaggtc
    26701 catgaagaat accttagagg aagtacggaa gagctactcg cttatatcga agaacatcca
    26761 gtaaagggtg aatgttgtct gcttgtagaa gggaatttgt tcgaaatgcc agtgacggaa
    26821 gttgatgaag agttgggaac gttaaaggaa caagtagaag caaagatcgc ttcaggcgaa
    26881 aaaccaaatg ctgctatcaa agcagtagcg ctgaaaaatg ggctgaaaaa acaagaagtc
    26941 taccgtcagt accatgaatt agactgagat agtataagtt gtctataatg aaagactaat
    27001 gaggaaatca gctactaact tttcaaatct cttgaacgcg aacgaatgtt cttgtataat
    27061 gaataagagg tgaggatgat ggagctgcaa tttcctttac ataatgatac atcaagaaaa
    27121 atcattcata ttgatatgga tgcttttttc gcttcggttg aagaacgaga tcatcctgag
    27181 tttcgcggac atccattagt aattgccaga caccccagtg acactggtgg gcgtggagta
    27241 gtgactacag caaattatga agcaagaaaa ttcggaattc attcagcaat gagtgcacaa
    27301 aaagcgtatg agctttgtcc gcaagccatc tttaagcctg gcgaccatca taaatacagc
    27361 gatatttcca aacaagtacg ggaagtattc tatcgttata cagatattgt ggaaccagtt
    27421 agtatcgatg aagcgtatct tgatgtgacc gaaaataaaa tcaattgcaa gtcagccatc
    27481 aaaatcgccc gaatgatcca agcagatatt tgggagagtg tccagctaac atgttctgcg
    27541 ggagtaagtt acaataagtt tttggccaaa ttagcatcag actatcaaaa acctagagga
    27601 atcacggtag ttgcccctca agacgctgtg ccatttttaa aagctttgcc aattgaaaaa
    27661 tttcatgggg tagggaagaa aactgtacct agaatgcatg agctagggat ttatacagga
    27721 aaagacctat atgaatgcac agaaatgatg ttgattcgaa attttggaaa aatgggctat
    27781 tctctttatc gtaaagtcag aggaatccat gattctccag taaacgttac aagagagcga
    27841 aaatctgtgg gaaaagagca tacttatggg cagccgttgc aaacggaaga agcagtgctg
    27901 actcagttgc gccaactagc tgaaaaagta gaagaagcac tgagaagagt ccaaaaacat
    27961 gggaaaacag tagttttgaa ggtcaggtac acggactatt ctactgtgac caaaagagtg
    28021 acattgccag aatatatcta taaaaaagaa gcactctttt atcaagcaag ccttatatgg
    28081 gaggaaatct tgggagtaga aaaaggaatc cgattgttag ggattacttt gacgaatctg
    28141 gacccgatga cttatgaaaa catcgtcctt ccattatggg aaaatcaaga aatataaaaa
    28201 cagctttgag agttgaaacc ggaaatccgt tttctctccc aaagctgttt ttatatcaag
    28261 tcttgctttt tgatttgttc ataggtttct gttgcatccg tacatttttc ccaaatcaca
    28321 acttgattgg attctaaaga tttttggacg tcaatgatcc gctggttgct acttccgcga
    28381 aattgtagtt ttaggtcacg tttgcttaat tcaaagcgtc cgtcaacaag gatatcgatt
    28441 tgcgaaagga gttctaattt atcttctgaa tcttgtagca attcatcaaa ggtatagcct
    28501 gtccatgacc agatatcttt tgtcgtaccg aactcttttc ggatacgtcg tacgacttgc
    28561 agacaaacat ctgtattcaa aaaaggttcg ccaccaagta aagttaatcc ttgcacgtaa
    28621 tcgttgcgca agtcagcgat gatttgttct tctaattcag gtgtgaatgg tttgccatat
    28681 cggaaatttt gtgcagcttt gttgaagcag ccttcgcagg caaataagca gccactaacg
    28741 taaagactgt tgcggacacc ttcaccatcg acaaaattaa acggtttgta gtcagcaata
    28801 tagttttggc tgtagtcttt tgctaaccat tcttttggtt ttggatttct cataaaaaaa
    28861 cttctttcat ttaaggttca aagatatagc tattgaagat aaaatctact cgaccacata
    28921 aataagaaca aactgaccta aatccattgt tcaagaaagc ttgttcttat tttgatagag
    28981 ggcgttcaaa gatacaaagc catcgaaaga gggtggtgaa aaaagacttg tcatagcctc
    29041 ttattctgaa taaacggtgt tcaaaagctt gcatctgcag taataagccc aactaaacga
    29101 aaaatatgag gaactatttt tgtttagcta ttcttattac ttgatgcagg acagcttttt
    29161 cacaacctca tttcatgtgt ttcacacgtg aggaaatttc tttatggcgg ccatgtacca
    29221 tcggacgagc ttgcggattt cctaaatagc cacaagtacg tttgactaca tcacatgttt
    29281 ttggatcatg atttccacat tctggacatt cgaaccctcg ttctgtcggt ttgaaatcac
    29341 cttcgaaacc acattgatag caatgatcga ttggcgtatt cgtaccaaga tacccgattt
    29401 tgtcatatgc aaaatcccat acagcttcta aagctttcgg attttgttgg agcatagggt
    29461 attcacagta gtggatgaat ccacctgaac aatattttgg ataatccttc tcaaattcca
    29521 atttttcaaa tggcgttggg tttttacgca catcatagtg gaaactgttt gtataatatt
    29581 ctttatctgt gatattttcg atgatgccga atttttctgt atccaaacgg cagaaacggt
    29641 cagttagact ttcacttgga gttgaataga cactgaaatg ataaccatat tcatcccccc
    29701 atgcatctgc attagctttt aattctttga cgatatcaag tgtgaaagct tttgcttctg
    29761 ggtttgtttc ccattcgcca ccgaagaaag ctgaagcaac ttcatacaat ccaatgtagc
    29821 ctaacgatac agtagctcga cggtttttga ataattcatt gacagaatcg gtacgtgaaa
    29881 gacgtttccc gaaagcacca tacatatata aaattggcgc atttgctgga atggcttctt
    29941 tacaacgttc tacacgatag agaagcgcat ctttcatgat ttctaagcgg tcagacagta
    30001 actgccagaa tttattctga tctccttttg attcgatcgc gattcttggc aaattcaatg
    30061 taacaacacc taaattcatt cgtccgacat ttacttcttg accattttcg tctttccacc
    30121 cttgcaagaa tgaacgacag cccataggta ctttgaaact tccagttaat tcaacgattt
    30181 tatcgtaatt cagaatatca ggatacattc ttttcgttgc acattccaat gctagttgtt
    30241 tgatgtcgta attaggatct tcagggttta agttcacacc ttttttcaaa gtgaagatca
    30301 gtttagggaa gatagctgtc cgcttttcac tccctaatcc attgattcga atctgtaaaa
    30361 ttgctttttg aatttctctt tcaaaccagt tttctcctag tccaaatcct aatgaagtga
    30421 aaggagtttg tccatttgaa gtaaataagg tattgatttc atattccaaa ctttgcatag
    30481 catcgaagat atcttttttg gtttttgctt ttgcatattc tttttggcgt tctggcgaat
    30541 cgatccattc ttccgcgtct tttagatgtt ttttatagtt caattctgca aaaggagcaa
    30601 gcaattcatc tgttcggtcg gcagaacagc caccatattg acttgacgct acattggcaa
    30661 taatctgtga gatttgtgct gtggcggtct ggatagattt tggcgattcg acttcggcat
    30721 tgccgatttt gaacccattg ttcagcatgc ctttgaaatc aatcaagcag caattcgtca
    30781 tcggtgtata aggatgataa tccaaatcat ggtaatggat atcgcctttt tgatgcgcat
    30841 ttgctatatg tggtggcaac attttcagtc cgattgattt tccaacgatc ccggctgtca
    30901 gatctcgctg tgtattgaaa acattactgt ctttatttgc gttttcgttc acgacagttt
    30961 ggtccttgtt gattagcttt tcaatcgaaa agttgatatc tgttgcttta ctgcgagcaa
    31021 aatctcgttt ggtacgataa ttgatgtact cttctgctaa ttcatattcg tttttttcta
    31081 gtaatatatg ttccacgatg ttttgaatct catagatttt gacattttca gcaaaccggc
    31141 ttttgatttc ttggacaacc aagtctgcaa tcatttgaat tttttcataa gtaagtggtg
    31201 ataatgagcc gtgaattttc ttttctgctt tgatcagtgc ttcattgatc ttttgttcat
    31261 cgaaatcaac atggcggcca tcgcgtttga tgactttcat ctgggatgtc tctggctgct
    31321 gagtaacgac agttttttct tcataattta ctttcattat cttcaactcc tgctaaattg
    31381 ttcttgtcta tcataaaaca aaatcgggga aggagcaact aaatatcggc tatatatagt
    31441 attcaatgtg ctgtataatt ggatttctat actatatgta gtgtatattt tattgtgaaa
    31501 aaaggtgaaa acttgtagct ggtggatttg ttttttgcat atttaatttt gctgaataaa
    31561 ataattgaat aaaatttttt attcagtcca agtaaaagtg acaaaaacat aagagcaaat
    31621 tattcgtaga tatgctacta tgcaaataaa tagaaatgaa aaatgaaaga ggaggagaag
    31681 aattggaaaa gatgatcgaa gtgaaacatc taagtaaaag ctacggcagc aaactttctc
    31741 ccgtcaaagc cttagataat atctcattca cagtagaaga aggcgagttt gttgggatta
    31801 tgggcccaag tggtgcagga aagacaacgc tgatgaatat cttgtccacg atcaatttgc
    31861 ctacgatggg cagtgtctcg atccaaggaa aagaaatcac aaaaatgaaa aacagtgagc
    31921 tcagtgactt tcgtcgaaaa aaactaggat tcatttttca agagttcaat ttgatcgata
    31981 ccctaaatgc aaaagacaat atcctattgc ccctagcagt tgaacggatg actaaagagg
    32041 aaatggaaaa gagagtaaga catgtagctc aattgttgaa tatagaagaa ctgctcaaac
    32101 ggtatcccga tgaactttct gtcggacaga gacaacgaat tgcagctgct agagcacttg
    32161 ttgttcagcc acaagtgatt tttgcagatg aaccaactgg ctctttggac tcgaagtcgg
    32221 ctacagaatt gttgaactac ttgaagacca tgaatcaaaa agaaaaagca acgatactgt
    32281 tagtcactca tgatccatat acagcaagct actgcgatag aattttattt attaaagatg
    32341 gtgtgatttt ttctgaagtt gtcagaagag ggacaagaag agagttcttt gagaaagtaa
    32401 tagacatgca ggcgacgatt ggcggaggag gaaaaatgaa tgctgtataa actagccgtt
    32461 aaaagttttt ttcggcagtc acgaggctat cttgtttatt ttttcagttt gactttatcc
    32521 gtaatgatct attattcctt cagcgcaatg acctacgatc aatctttagt cagaagagca
    32581 agtcaagata cttcgataga tggtggattg agttttggtg gatttatcat tactgttgtt
    32641 ttgctttttt tcgtattcag tgccaaccga tttttcttga atagaaggca aaaggaaata
    32701 ggcatctatc agctttttgg tatgaataaa ctgcagatat caggtatata tgtgttagaa
    32761 atcatgataa ttggattgtt cgcctgtatt tctgggatat tactcggtat tattttttcc
    32821 aaactctttt caatgatttt ggttcgaatg atggatatgg atcttactag tccatttttt
    32881 atctccattc catcagtagt agatacttta tttgcttttt tcatcatcct tttagcagta
    32941 tctgtatatt caatatggaa aatatggcgc tatccaatga ttcgaagttt tggagaaaaa
    33001 gaacaagcag atagttcaac aatgcgcttc aggacaaggc accgattact cgcagtcatc
    33061 gggttactac ttttaacgag cggatatttt ggagctagtc attttaggga aatcacttca
    33121 tggatgatca gttatcatta tcttgataca ttagttttct tttttccttt tttaattttt
    33181 ttcgtttgtg tggtcggtac ttatttgttt ttctgttata catttcggtt atttttgatc
    33241 atattgagta aatggaagat ttattactat ggtatcaatt ttttgataat gggtaacacg
    33301 caagttcatt tgctcaaaag ttggcgtaca aattctctga ttacagtcat tctcggaatt
    33361 tctttaatga caattggcgg cacggctagt atctctacta ttttatccta ccaggagaaa
    33421 gtttcctccc cgatggacta tcagtttgat gttgagacag agaaaaaaat caagccgatt
    33481 ctagcagagg aagggcagaa gataactaaa gaaatcacct tgcattataa agtcattggg
    33541 agtatctata gtcaaaatct cgaagaacct atgtttcaaa ctgctaatct gatcacggaa
    33601 acacaatatc aagccttcag aaaagttaat ccagatttgc cgaacatttc tttgaaatca
    33661 cctggtcata ctgttttgct tgatcaaatg caaactcttt ttcggaatat ttcattatat
    33721 ggatctagta ttggactgcc agataatcaa gaattgaaga ttcaacaaat gcttccaagt
    33781 gtattaggtg acgaaacaat ggtatatcta agtcctgtac tgattgtaga tgataccgtt
    33841 tttgaaaaag caaaaggtgt ggattatcaa gtagtcaatg tagatgtatc aggtggaaat
    33901 aatgaaaaaa tagatgaacg actgagcaat gacctgtcga taaagtggct caatgctgtt
    33961 tattattctt atgatatcgt aaatggaagt ctacaaggag aaattagcac aaagaaactt
    34021 ccggatgacc aaatgaagga agcacaattt agccaagaaa gctctcgttt gaatttctct
    34081 tccagctatt cgaaattgcg tgcagttaat cggcgaatcg gtatcaatat ttttgtcaca
    34141 ctatttgtcg ggatgatcgt gattattgct actggtagta ttttgacagt ccggcaatta
    34201 gcagaagcag aggaagaaaa agaaaattat cacctattga ctaagctggg gattccacaa
    34261 agaaggatca gacggatgat cttcgagcaa aacgcactta ccttctttcc acccatgata
    34321 ttagggatca ctcacgcagt atttgcaatc aatgtcttca ctcagtatat aaaaactgcc
    34381 gattactggt tggcttatct tgtgagtggc ttattgatcc ttatctatct tttgctttat
    34441 gtcattacga gtcagttata ttgtcggatt atcgaggaat gatatacgga ataagacaag
    34501 ataataaata gaactaaatt ttgaatacca tttatttgga ataagaggtt gtgacacgat
    34561 ttttgtcaca acctctttat tttttatatt ttttaaaagt acgagaaatt ataaagaaaa
    34621 aagcagtgat ttgatgtgct atttttataa aagctatgtg acaaaactgt tagtaaaaaa
    34681 acggtttctg taagctagac acatgtttct ttttgtcaaa attagttaca ctttgtgtga
    34741 ggttatatga ggagggaatc caatgaacaa atggcgttct aatccaaaat tgaattattg
    34801 gggaaaattc atcattcgaa caatttttta tagtgcagta ctgctgttcc tgatttatct
    34861 gtatcactat aaaaatattc aaggaggaac ttttatctat aacgaatttt aggaggaaga
    34921 gtatggaaat caaaacgatt attgaagcaa tcgatgattg gggaataaat gaacctgatc
    34981 gagttgctta tcaggcggat gagacgcata cttttggtga attgaaacaa gcatcagacg
    35041 cacttgctta ttatttagaa aaaaaggtag aaggcgatgg accaattgtc gtttttggca
    35101 atttggagtt tgaaatgatt gtctcatttc taggggttgt caaatctggc catgcctatt
    35161 tgccgattga agagcataca cccaaggagc gtatcctatc gatctttcgg gtggctaaac
    35221 catctatggt catcagtatc ggggactgga tagaagatat tccttcggtt cctgtcataa
    35281 caaaaaaaga atttcaagaa atcaagaaga taccagtagg attttatccc agaaatagcg
    35341 taaaaggtac agaaaatttt tatattattt ttacttctgg tactactgga gaaccaaaag
    35401 gcgtacaaat cagtcatgat aatctagtca gctttgttca atggacgatg gaagactttg
    35461 ggatcaagcc tggtatgcat ttcttagccc aagcgccatt ttcttttgat ttatcggtat
    35521 tttctattta tcctgcatta gtttctggcg gaatgctgaa gccgttaaat aaagcagttg
    35581 ttcaagactt tcgtcaatta ttcgcgacat tgccagcctt gaagttgaat gtgtgggttt
    35641 ctactccatc atttatggat atttgcttga tggaacctac attcaatgga gaaaatgtgc
    35701 cggaattgga catgttttta ttttgcggag aagaattgac gaaaaaaact gcagaaagtc
    35761 tacttgatcg attcccaaat gcacggatat ataatactta cggtccaaca gaagcaactg
    35821 tagctatttc aagtattcag attgaccagc atgtactaga tagttatgac cgactaccga
    35881 ttggctacgt aaaaaaagac acgaaagttt ctattgtcca agaaggtaaa cctgtttcaa
    35941 aaggagaaac gggtgaaatc attattgcag gaccaagcgt atcaaaaggt tacctgaaca
    36001 atcccgaaaa gacagctgct gcgttctttt gtcaaaatga cttagcaagt taccatacag
    36061 gggatgcagg tagactagat gaatatgggc ttttatttta tgaaggacgt atggatcagc
    36121 aggtcaaatt acatggatac cggattgaac tcggggatat cgaacattat ctgctccaag
    36181 acaaccgaat caaacaagct gtcgtcgtac caaaatacca aggaacaaaa gtacagcagc
    36241 tggttgcttt tgtcgtatta gaaaacaaaa cgaaacagcc ggattttcag ttgactaaat
    36301 ctatcaaaga acaattacta gaagttgtaa tggattatat gattcctcag aagttccatt
    36361 atgtcgatct gctgcctcag acagttaatg gaaaaatcga tcgaaaaaaa ttaacagctg
    36421 aggtgaatcc tgaatgatgt tacctcatat gatcccttat gcagagccgt tttatttttt
    36481 tcttttagcc attgcgcttg taccgatcgt tctatcttta ttgatatggg aaaaaagatt
    36541 accagtttat caatcagcag tgacactttt ctttttattt gtcagctttg gaggtaatta
    36601 ttggcaacag ggagcggcgc tgattgggta tgttttgtgg cagacgatac ttgtatgggg
    36661 ctattttgtt tatcggcaaa ggaaaaatca gacaggatgg ttttttgccg ccgttatttt
    36721 agcgataatt ccactgtttt taacgaaagt gactcctttt tttgaacatg gaaaagcatc
    36781 gttacttggt tttttaggaa tctcttattt aacctttaaa tctgtacaaa tgatcatgga
    36841 aataagagat ggcatgatca aaacatataa gccatttcgt tatatccagt ttctgctgtt
    36901 ctttccaaca atctcttctg gaccaatcga tcgctatagg agatttgaaa aagatcagct
    36961 ccatccgcct gttcgtgata aatatgttga tcttttggga aaaggcgtcc aaaatatttt
    37021 tgtcggtttt ttatataaat tcattatcgg ttattatttt ggtcaagtac tgcttcctgt
    37081 agtgggacgc attgccttac agcatggtgg tatttcatgg gcattagtag gttatatgta
    37141 cgtgtacagt atgtatttgt tttttgattt tgctggctat agcttatttg cagtcggtac
    37201 aagctacatg atgggatatc agacaccaat caatttcaat aaaccttttt tatcatggaa
    37261 tatcaaagaa ttctggaatc gttggcatat gacgctgtcc ttttggttcc gtgattatgt
    37321 atatatgcga ttgatgttct tcatgatgaa gaaaaaattt tttaaaagca agatcgtaat
    37381 gtcaaatatc ggttattttg ctttgtttct tctaatgggt atatggcatg gattgacgtg
    37441 gtactacatc gtatatggac tgtatcatgc ttgtctgatc tgtctgacag atgcatggat
    37501 ccgatttaag aagaagcata aagagcagtt gccttctaac aaatttacgc atggcttagc
    37561 cgtatttttg acatttcaag cagtatgttt tagcttcctg attttttcag gatttttaga
    37621 taaacttttt tttagctaac gaatagtgac atattaattt atataacaaa ggagaaaagg
    37681 aaaatggaag aacaaatttt atcaatctta gaagaaataa caggaacaga tgaagtaaga
    37741 aaaaatcgtg atattgatct atttgatgaa gggttgcttg attctttagc atctgttcaa
    37801 ttattagtcg agctagacgg agagctggat atccaagtcc ctgtatctga attcgagcga
    37861 gaggattgga gcacaccgaa taaaatcatt caacaagcaa ctgcattgaa gggttgagta
    37921 tgaaaaagaa actttttgct attttcggcc cggttgtttt agctgttggc ttactgtttg
    37981 tgttttttac ctcctcctat caagtagata tctctaatcc agaaacgatt agacgtgcct
    38041 cttcttccat gtcagtgaac gtgttgaaag gagatgcgat aaaaaattat gcattatctg
    38101 aaaaacaata tattcctttt tttggctcaa gtgaattaag cagaatcagt ccatttcatc
    38161 cgtctgttct ggcagaaaaa taccagcgaa actatcgtcc atttttgctg ggagcacccg
    38221 ggacacaatc gttaagccaa tatatgatga tgcgttctgc aggagatgct atgaaaaaca
    38281 agaaagtcgt ctttattatt tctcctcagt ggttcgttaa aaatggtgta aaaactgatt
    38341 actttaatac gtattattct gaacttcaaa catacgactg gttgttttca atgaagaaag
    38401 taacgcctgc tgatcgctat ttagctagaa gattattaac tttctcaaaa gtaaaagaga
    38461 atgatacgtt gacggcgatt ctgcaaacga tcaaaaaagg gaagctacct ttacctgaat
    38521 ctttgaatca gctgcgcagc caatggaaca tgctgaagag agaggatgaa gtattcagca
    38581 atattgggtt gaaagatcga cagcaaaaaa tcgatcatga gtcaaaacga ttaccaaaac
    38641 aataccaaga aacagaatta tccattttag caaatcaaat tggagaacga gaaacgacga
    38701 ataatccatt cgggttgaaa aacgattttt atacgcatcg tatccgagcc cacgagccag
    38761 agctcaaaca gtcacaaaaa aattgggatt atcgtttttc gccagaattt tctgattttc
    38821 agctggtctt ggatcaatta gcaaaaaacc ataacgaagt attgttcatc atcccaccgg
    38881 ttaacgagaa atggagcgat tataccggac tatctcaaga aatgttacaa ggatttgcca
    38941 aaaagatcaa atttcaatta aatagccaag gattcaatcg aatagctgat tttgtcaatc
    39001 aagcgggtac caactatttt atggaagaca cgatccatct aggctggaaa ggctggttgg
    39061 ctgcagatca acagatcaga ccgtttttag aagaaaatca tattactgct agtaagtatc
    39121 atcttgacga tgcttttttt agcaaatctt ggcaacatca aataccagat aaactacaat
    39181 taaaataaag aaaacaggcg agtgttgctc gcttgttttc tttatttttg aatattctga
    39241 ataaaagata aaaataccaa gtttgcctga acaaaaatca taagcaatgg tataatcaca
    39301 atatgaatat agaaatgggg gaaaacattt ggatacaaaa gaagaacagc tacttattga
    39361 tttaacttct gcaaaaggag tacctggaaa tgaagaagag gtaagagaag tattcagaga
    39421 atatgccaaa ccattcgctg atgatatttt ttatgacggt ttaggcagtg tgattgccaa
    39481 acatggtgct ggcggaggcc ccaaggtctt tatttctgga catatggacg aagttggttt
    39541 tatggtaaca aaaataaccg aaaaaggatt cttggaattc caaactcttg gaggttggtg
    39601 ggggcaagtc atgcttgctc agcaagttga aatcaaaaca cgtgaaggga aaatcgtcca
    39661 cggtgtgatt ggttccaaac caccacatgt tttaacacct caagtaagaa ataaacctta
    39721 tgaaataaag gatatgttca ttgatattgg cgcatcaagc caagaagaag ccaaagagtg
    39781 gggcatacgt cctggagata tggtcactcc atatattgaa tacaaacgaa tgaatggcag
    39841 taaatattta ctggcaaaag catgggataa tcgtatcggg acagctgttt ctctgcgagt
    39901 attagagaat ctatctaaag aagcacaccc aaatgtttta ttcgcaggaa gcgatgtgca
    39961 agaagaagta ggcttgcgag gtgctcgaac aagtacacac cttgtaaatc ccgatattgc
    40021 ttttgcttta gatactggta cagcaggaga cactccagga atgacaccaa aagaagcaga
    40081 ttcgatttta ggaaaaggcc cacagatttt gatttttgat gcatctatga tcccgcataa
    40141 aaaattattg aattttgtta ttgatgtagc agaggaaatg gatattccat tccaatatac
    40201 agtgatttct ggcggaggaa ctgatgcagg acaaatgcat ttgacaagag atggtgttcc
    40261 gtctgtagcc attaccgttc ctgttcgtta tctgcattcc catacatcag tgattcatga
    40321 agatgattat ttgaatacag tgaaactagt cacagaatta gtgaaacggc ttgatagtga
    40381 aacagttgaa aaaattcgga gttatgaata atgaataata gaat
//
LOCUS       DAKCAA010000022        39263 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000022 DAKCAA010000000
VERSION     DAKCAA010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.022"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            299..1960
                     /locus_tag="OUE31_001240"
     CDS             299..1960
                     /locus_tag="OUE31_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCU0222259.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2377)
                     /locus_tag="OUE31_001241"
     CDS             complement(2030..2377)
                     /locus_tag="OUE31_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HCU0222260.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2461..3402
                     /locus_tag="OUE31_001242"
     CDS             2461..3402
                     /locus_tag="OUE31_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222261.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3403..4446
                     /locus_tag="OUE31_001243"
     CDS             3403..4446
                     /locus_tag="OUE31_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222262.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4452..5522
                     /locus_tag="OUE31_001244"
     CDS             4452..5522
                     /locus_tag="OUE31_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222263.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5512..6465
                     /locus_tag="OUE31_001245"
     CDS             5512..6465
                     /locus_tag="OUE31_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0222264.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6477..7487
                     /locus_tag="OUE31_001246"
     CDS             6477..7487
                     /locus_tag="OUE31_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0222265.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7772..8593)
                     /locus_tag="OUE31_001247"
     CDS             complement(7772..8593)
                     /locus_tag="OUE31_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCU0222266.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8690..8968)
                     /locus_tag="OUE31_001248"
     CDS             complement(8690..8968)
                     /locus_tag="OUE31_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222267.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9236..11245
                     /gene="metG"
                     /locus_tag="OUE31_001249"
     CDS             9236..11245
                     /gene="metG"
                     /locus_tag="OUE31_001249"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HCU0222268.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11724..12311)
                     /locus_tag="OUE31_001250"
     CDS             complement(11724..12311)
                     /locus_tag="OUE31_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222269.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12486..13808
                     /locus_tag="OUE31_001251"
     CDS             12486..13808
                     /locus_tag="OUE31_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0222270.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13963..14739
                     /locus_tag="OUE31_001252"
     CDS             13963..14739
                     /locus_tag="OUE31_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCU0222271.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14732..15301
                     /gene="rnmV"
                     /locus_tag="OUE31_001253"
     CDS             14732..15301
                     /gene="rnmV"
                     /locus_tag="OUE31_001253"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HCU0222272.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15294..16178
                     /gene="rsmA"
                     /locus_tag="OUE31_001254"
     CDS             15294..16178
                     /gene="rsmA"
                     /locus_tag="OUE31_001254"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HCU0222273.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16629..17258
                     /locus_tag="OUE31_001255"
     CDS             16629..17258
                     /locus_tag="OUE31_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222274.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="OUE31_001256"
     CDS             complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="OUE31_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HCU0222275.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18700..19122
                     /gene="mgsA"
                     /locus_tag="OUE31_001257"
     CDS             18700..19122
                     /gene="mgsA"
                     /locus_tag="OUE31_001257"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HCU0222276.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLQDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19445..19981
                     /locus_tag="OUE31_001258"
     CDS             19445..19981
                     /locus_tag="OUE31_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCU0222277.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20021..21784)
                     /locus_tag="OUE31_001259"
     CDS             complement(20021..21784)
                     /locus_tag="OUE31_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222278.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21787..23502)
                     /locus_tag="OUE31_001260"
     CDS             complement(21787..23502)
                     /locus_tag="OUE31_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222279.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24281..24505)
                     /locus_tag="OUE31_001261"
     CDS             complement(24281..24505)
                     /locus_tag="OUE31_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222280.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24696..27473
                     /locus_tag="OUE31_001262"
     CDS             24696..27473
                     /locus_tag="OUE31_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCU0222281.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27554..27973
                     /locus_tag="OUE31_001263"
     CDS             27554..27973
                     /locus_tag="OUE31_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HCU0222282.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27985..28455
                     /locus_tag="OUE31_001264"
     CDS             27985..28455
                     /locus_tag="OUE31_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0222283.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28472..29251
                     /locus_tag="OUE31_001265"
     CDS             28472..29251
                     /locus_tag="OUE31_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCU0222284.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29238..30059
                     /locus_tag="OUE31_001266"
     CDS             29238..30059
                     /locus_tag="OUE31_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCU0222285.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30076..31125
                     /locus_tag="OUE31_001267"
     CDS             30076..31125
                     /locus_tag="OUE31_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCU0222286.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31138..32142
                     /locus_tag="OUE31_001268"
     CDS             31138..32142
                     /locus_tag="OUE31_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCU0222287.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32775..33794
                     /locus_tag="OUE31_001269"
     CDS             32775..33794
                     /locus_tag="OUE31_001269"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCU0222288.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            33837..34718
                     /gene="galU"
                     /locus_tag="OUE31_001270"
     CDS             33837..34718
                     /gene="galU"
                     /locus_tag="OUE31_001270"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCU0222289.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            35018..35395
                     /locus_tag="OUE31_001271"
     CDS             35018..35395
                     /locus_tag="OUE31_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222290.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            36001..36615
                     /locus_tag="OUE31_001272"
     CDS             36001..36615
                     /locus_tag="OUE31_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCU0222291.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            37388..39127
                     /gene="yfcC"
                     /locus_tag="OUE31_001273"
     CDS             37388..39127
                     /gene="yfcC"
                     /locus_tag="OUE31_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCU0222292.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
BASE COUNT        12817 a         6846 c         8049 g        11551 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgaggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt ttttcatttg attgctcctt tatttttggt
     2401 tcattatcta ataatgtagc gaaacatctg tcagaagtca aaagctaggg ggaaacatta
     2461 gtgaatagtt atatcaaata tgtattaaaa cgtgtctttt tcatgatcat cacgctttgg
     2521 ttaattgcaa caatcacctt tttcttgatg caattgctgc cgggcacgcc atatacgaat
     2581 caggaacgtt tgagtcctga aacaatcgag atgctaaata aacaagtcgg tttggataaa
     2641 ccagttatcg tacaatatgg gatttatctt tctaatttgc ttcaaggaga ttttggaatt
     2701 tccttccaat ttaaaaacca gccagtcgca catttgttag ctggaagaat cggaccatcc
     2761 ttgcagttag ggttacaggc aattatcttt ggaacagtcc tagggacgat tttaggaacg
     2821 atctctgcca tgaagcaaaa tacatgggca gatacatctt ctacactcgt agcgatatta
     2881 ggtcgttcca ttccaaactt tgtatttgct gttttattac aatatatctt tgcaatcaaa
     2941 ttacaagttt tgccaatcgc aaaatgggat ggctttgtgt acacaatctt accaacaatt
     3001 gcgttggcca tgtcgccgct tgctgactct gctcggttta tccgtacgga aatggtggaa
     3061 gtactgcata gtgattatgt ggaattagca aaagcaaaag gattgagccg ttgggaaatc
     3121 gcctttaaac atggtcttcg aaatagtttg attccattga tgactttatt aggaccgtta
     3181 gctgtagcat tgatgaccgg atcactggtg gtagaaaata tctttgctat tcctggtatc
     3241 ggggaacaat tcgttaagtc aatcacaaca aatgattatc ctacgatcat ggctgtaacg
     3301 atcctttact catttatgct gatttttgtt attttgatcg tggatctatt gtacggtcta
     3361 gttgatccaa gaattcgtgt ttcagaaggg agccgaggat aaatggaaat gataccaaag
     3421 cgttatgaaa cagttgcaga tatccctgcg gatgaatttc ttccattaca aaaaaatacc
     3481 gaagaagaac gtgaacagat tactgcacct tctttgaatt ttatccaaga ttcatggcgc
     3541 cgtttaaaga aaaacaaagc tgccgttatt tcaatggttt tactattggt catcattttg
     3601 atctctgtga tcacaatctt tgtttctcct catgatccaa ctgcccaaaa cgtggcttat
     3661 atcaatttgc ctcctcgtat tccgggaatc aatatcgatg gattgaatgg aaaagcaatg
     3721 gttggtggtg aacttgttga taaatatgct caagcaaacg tcccttcaaa cgtaaatttc
     3781 tttttaggaa cagacggttt gggacgtgat gtattaagcc gcttatttat gggaatgaga
     3841 atctcgttgc tgatcgcatt tattgctgca ttactagatg taacgattgg tgtagcttac
     3901 gggttggttt ctggtttgtt aggcggacgt gtcgataacg tgatgcaacg ttttttggaa
     3961 atcttatcag gaattccaaa cctcgttgtc atgattttga tgttggtcgt ttttgaacca
     4021 ggaatttttt caatcgtggc tgctatggcc atcacaaact ggataccaat ggcacgtatc
     4081 gttcgtgcac aaacaatgaa attaaaagat caagaatatg ttttagctgg attgacatta
     4141 ggtgaatcaa gaatgaaaat tgcattcaaa catattttgc cgaatatctc tagtgtcatt
     4201 attattcaaa tgatgtttag tattccatct gctattttct tcgaagcctt tttaagcttt
     4261 atcggtttag gtcttacgcc tccgtcagct tcattaggaa cgatgttgag cgaagggtac
     4321 aagacattcc tgtatctgcc ttatctatta tggattccgg cagtaacttt atcggttatc
     4381 atgattggct ttaacttact tgctgatgga ttgcgtgatg cctttgatcc taaaatgaaa
     4441 gagtgaagac gatgacgaaa attttagaag tgaaagactt agaaatctct tttgatacgt
     4501 atgctggaaa ggtacgagcg attcgcggtg tcaattttca tttgaataaa ggagaaacat
     4561 tggcgatcgt tggggaatct ggaagtggaa aatcagtgac gaccagaagc atcatgcgct
     4621 tgctgtcaag caacgccaat atagatgctg gtcaaatcct ctttaaaggt aacgatatcg
     4681 ttggaaaatc agaaagagag atgcaaaaaa tccgtggtaa agaaatagcg atgattttcc
     4741 aagatccaat gacctcttta gatccgacga tgcccattgg gaagcaagtc gctgagtccc
     4801 ttagaaagca taataaagtt tcaaaaaaag agggacaaaa agctgcatta gaattgctta
     4861 aattagttgg aatacccgaa gctgagaaac gtatcaacag ttatccgcat cagttctcag
     4921 gaggtcagcg tcaacggatc gtgatcgcga ttgcactggt atgttatccg gaaatcctga
     4981 ttgctgatga acctacaaca gcgcttgatg tgactattca agcacagatt ttggagctgc
     5041 tgaaagaaat tcagacaaaa atcgatacat caattatctt tatcactcat gaccttggtg
     5101 tagtagcgaa tgtcgctgat cgtgtcgctg tcatgtatgg aggaagaatc gttgaagttg
     5161 gaacatcgga agaaattttc tacaacccgc aacatcccta tacttgggga ctgcttggtt
     5221 caatgccgac attagatagt gcgaacgatc gattgtatgc tattcctggt tctccaccgg
     5281 atttattgaa cccgccaaaa ggagacgcat tctatccaag aaatgaattc gcgatgaaaa
     5341 tcgatgcaga acaagaacca ccattttttg aactatcaaa aacacacaag gcagcaactt
     5401 ggctacttgc tccgcaggca cccaaagtga caccgccaga agaaatccaa cgtcgctggg
     5461 ctatctttaa agagaaacaa aaacatactt acggtcaagg aggaattgct gatgccaaat
     5521 aaactacttg aagttaaagg attgaaacag tatttcaatg taggaaaaaa gaatgaagta
     5581 catgctgtaa atgacatcag ctttcacatt tatgaaggag aaacattcgg tttagttgga
     5641 gaatctggaa gcggaaaatc cactactggc cgtacgatca ttcgcttgaa tgaacctact
     5701 gatggtgaga tattattcga cggtcaagat ataacgaaga tcaaagataa aaaaggtttg
     5761 acgaaattcc ggcatgatgt tcagatgatc tttcaagatc catacgcttc gttgaatcct
     5821 cgtatgaaag tcagagatat cattgccgaa ggaattgatg ttaatggact agctaaatca
     5881 tctgaagagc gtgcaaaaaa agtcgatgat ctattgagaa ctgttggatt gaatccaagc
     5941 cacggtactc gttatcctca tgaattttca ggtgggcaac gccagcgtat tggtattgca
     6001 cgagcattgg cagtaaaacc gcgttttatc atttgtgatg aaccaatttc tgcactagat
     6061 gtgtcgatcc aagcccaagt ggtcaatttg ttgcaagatc tccaaaaaga acatcaattg
     6121 acctatctat ttattgcaca tgatttgtcg atggttaaac atattagtga ccgaatcggt
     6181 gtaatgcata acggcttgtt attagagatg ggaacaagtg atgaaatcta taatcacggt
     6241 gttcatcctt atacagaaag tttgttatct gctattcctc taccagatcc agaccatgag
     6301 agaaaacgca gaagaatcaa atatcaacct gaaccagatg acggacaagt acgtcaactt
     6361 cgtgaaatcg caccagaaca ttttgtctat gcaactgagc aggaagtccc atattacgca
     6421 aaaaaactaa aacgacaaaa ggaatctctt ctggttgcta actaggaggg acatagatgc
     6481 taaaagcttt taaattccgt atgtatccga cagaagaaca aaaacagcaa ttgattcgta
     6541 cttttggatg tgctcgattt acctataacc atttgctgaa aaagcggcag aaaagttggc
     6601 aacaaacagg agtagccaat ttttcgctca cacccgctac attaaaaaaa gaatacccat
     6661 tcttaaaaga agtagacagt cttgctttag caaatgcaca gcttaatttg gatcgggctt
     6721 ttcgcaatta tttcaaggga cgtgccagct tcccaaagct taaaacgaaa aaaagtatgt
     6781 ggcaatctta tacgaccaac aaccaaaccc gtacgatcta tctggaaaat ggctacttaa
     6841 agttaccaaa acaaaaagaa ctaatcaaga taaatcagca tcggccagtt gaaggatcga
     6901 ttcgctccgc tacgatttct gctcgatata atgaagaatt ttatgtcgca ctactttgtg
     6961 atgtttcgcc agtaaaaaaa gaatctttag ctaaatggat cgggatcgcc tatcatccga
     7021 agacattgat ccaaacatct cgacctctag aagtaacttt accaaaattt caccagacag
     7081 aagaaaagct gcaacatgca cagcggaaat tgaatgtgaa agtccgctcc gctcaccata
     7141 gaaagatcag gttagatcag gcaagcaatt atcagaaaca aaagagaaaa gtaatggatc
     7201 tttatctgaa acaaaagaac cagcgagaag attatcttga acaattatct gggaaattgg
     7261 tcaaacaata tgactactta tttgtagaat cttttccaaa agaagaggca catgctgatt
     7321 tttctattca cgactggcat aaattaataa caaaattgcg ttataagtcc caatggtata
     7381 ataaaaaatt tcttttgatc aataccgacg gagcagaaga aagcaattcc gtaagaaaga
     7441 gccaagtagt agaaaaaatg ggcagacatt cggttatcaa gggataaaaa atgaatgaaa
     7501 ctgataggag cgttagggtt agccttgtta ataaaaagtc ttaatgactt ttgtttctag
     7561 gaatttttct tttgaagaaa agctcactaa ttatgacaaa ccaataaaac aatagcagaa
     7621 aaagttcgta cgagcttttt ctgctattgt taatttttta ttcagaaagt ttacgaatac
     7681 atcaaaattc tgaaacaaaa aacgtaactc acaaagagtt gtttttgcgt tttttcttga
     7741 atgattaggt ctgaatcttt tgctcacaac cttattcatg gtgccccggc ttgagctgat
     7801 agatttttga aggacggccg attcctacag gacgttcacc gatctcatcg aaatattgga
     7861 gcatagcttt cttaaaattg gaatgatcga tcgttttata atcgatccct aagaatttag
     7921 caaatacttt tcgagcttcc gtaatcgtga aatctttacc taaaacttgt agaacttgcg
     7981 gctcgtgttc cattttattg actacacggt tgaatgcttt caagatgatt tgactatggt
     8041 caaaagccaa agtatctttg ccagaagact ctccagtgac taaatcaagc gagatagcca
     8101 cttctccgct agataaatgg atcttgttac tatgacgttc tagtgtgaac cagcgtactt
     8161 ccttggcatc atctccggcg attagcggtt cttctccaat aaaggctaag tagctgactg
     8221 tgacgaccca gcctcgcgga tctcgattag gcgtactgaa tgtatgcagt tgctcaatat
     8281 tttcttttga aataaccaca ccagtttctt cctttgtttc tcttaagacg ctttctccag
     8341 ttgactcatc cttttggaca aagccaccag gcaatgccca tgaatttcga taaggatgcc
     8401 cttttctttg gatcaacaaa actttcagct gatcttcttc tttgttatag cacatcagta
     8461 cgatatcgac agtcaaagag ggcttgtcat attctggacg ttcctgtttt tgataccagt
     8521 taagaaattc ttcttcactt gctttatgtt cataatataa tttttcttct tctttagaag
     8581 caaaacggtt catctgacca cctccattga cagtaaaagt actttttacc ttattgtagc
     8641 agactctgaa aaaaaaccaa ggatttactt gaaaaatcta ggttatcatt taaatatgaa
     8701 aaataaatgg aagtatgaga ttgaataaaa agaaaagcag ataaaacggc aatactttat
     8761 accgctcttc acgaatggca aagaagccac aaataacgat atatacgtca atgataaaac
     8821 gcaaaatcca agctgctgtc ataaaactgt tcaaatgccc atggaggtta aaataaccat
     8881 acatacgaat ataaaaatag ctgaatatta aatgtgctaa tgaaagaaaa gcaatactaa
     8941 gtgtaaaaaa aagatgtttc ttctgcatga ttgttccagt cccttactaa gatagatagt
     9001 ctttattata ccacgtgtga ggggagaaat aaaaagccgt tttttagtag atatgaaaca
     9061 aaacaaaaac ccgcatttat tcaacctatt catcctttta aaggatagat tgaacgtaga
     9121 tagaagtcgt ttatccagtc tttttcattt tgaaaaaaag ctaacagcat gcttttttta
     9181 tggtatacta gcaaggaaac gaattcgcat catgcgataa aggaggaaga gccccgtggc
     9241 agaaaaggaa actttttata tcactacgcc aatctattat ccaagcggca aacttcatat
     9301 cggcaactcg tatactacga ttgcatgtga cgcaattgct cgttataaac ggttgatggg
     9361 ctttgatgtg ttttatctca ctggagtgga tgaacatggt caaaaaatcg aaacaaaagc
     9421 agaagaacta ggtgtaaaac cgcaagaata tgtagataaa atggcggctg atgtcaagaa
     9481 attatggaaa acgcttgata tcagttatga taaattcatt cgcacgacag atgattacca
     9541 taaagcagct gttcaaaaaa tatttgatcg tttattagaa cagggagata tttacttagg
     9601 tgaatatgaa ggctggtact ctgtttctga cgaagaattc tttacagaaa cacaacttgc
     9661 agaagtgtac aaagatgacg aaggtaacgt gatcggtggt aaagcgccaa gtggacacga
     9721 agtagaattg gtaaaagaag aatcatactt cttccgcatg agcaaatacg cagaccgtct
     9781 attggaatac tatgaagaac atcccgaatt catccagcca gaatctcgta aaaacgaaat
     9841 gatcaacaac tttatcaaac caggattaga ggatcttgca gtttcacgaa caacttttac
     9901 ttggggagta ccagtcaaga gtgatccgaa acatgtggtg tatgtatgga tcgatgcatt
     9961 atccaattat attactgcac taggatatgg ctccgaagat gaaagtctat tcgaaaaata
    10021 ctggcctgca gatgttcaga tggtcggtaa agaaatcgtt cgctttcata cgatctattg
    10081 gccaatcatg ctgatggccc ttgatttgcc tctacctaaa aaagtatttg ggcatggctg
    10141 gctattgatg aaagacggaa aaatgtctaa atcaaaagga aatgtcgttt atcctgaaat
    10201 gcttgtggaa cgttatggtt tagatgcact ccgttattat ttgcttcgtg ctgttccgtt
    10261 tgggtcagat ggtgtcttta cgccagaaga ttttgtttcc cgtgtcaatt atgatctggc
    10321 aaatgatcta gggaacttat tgaatcgaac gattgctatg atcaacaaat attgtgatgg
    10381 actcgttcct gactatgcct cacttgtcac tccatttgat agtgaactgt ctacgacggc
    10441 tgctaacgtt gtcggacgtt accatgatgc aatggaaaaa atggaattca atacagcatt
    10501 ggctgaaatc tgggtgctga tttctcgtgc aaacaaatac attgatgaaa cagaaccatg
    10561 ggtattagca aaagacgaag aaaagaaagc tgaattgaat agtgtcatga tccatttagc
    10621 tgaatctttg cgtatcgcag cgatattact tcagccaatc atgacagaaa cgccagagaa
    10681 gatcttcaat caactaggat tggactctga aacaatgaat cttgaaggat tacactttgg
    10741 cgaatttcct tcaggaacaa aagtagttgc aaaaggtaca ccaatcttcc cacgtttaga
    10801 tatggaagaa gaagttgctt ttattcaaga aaaaatgtct gaaggtactc aaacaaacga
    10861 agatacagtc aaatgggatc cagaagaaac agaacttgtt tcaacgaaag aaaaacaaat
    10921 caaatttgat gtatttgaaa aagtagaact aaaagtagca gaagtcatca actgtcaaaa
    10981 agtagaaggg gcagataagt tgctgcaatt ccgactagat gctggagaca gccaagaccg
    11041 tcaaatcttg tcaggaatcg ctgaatttta tcctgatcca agcgaattga tcgggaaaaa
    11101 agtcgtcatt gtagcaaatc tgaaaccacg aaagatgcgt ggacaaatca gtcaaggaat
    11161 gatcctttct gcagaagcac cagatggctc tttacaagta atcgaagcac caaaatccat
    11221 gccaaatggc tcagaaatcg catagaaatt caaagggggt atgacactag ttgtgtcata
    11281 cccccttttt ccgaaatttg agaagcaatt ttcgtaaatt ccttcttatt acttgaagcc
    11341 aatcatataa tacagaaaca gagaactatc caaaataaat cctagaaaaa gaagtacgag
    11401 cttcgctgat ttttgttaat ttagaataat actaatagga atcgtaaaaa cagaaaaaaa
    11461 gcataatgat aaagggtcgg gcagatttta attgattcat ctggtactct tttttattgt
    11521 ccttacattc ataaagtttg aatgcaatga ctttattaca tctatattta tatctaacag
    11581 tagcgttgat gtgttaatta taagttctat cactttatgt tcaattagtt tgtgctctta
    11641 tatgtgtgat tgaaaatata gataaaaaaa caatcatcgg ctttgacttc gatgattgtt
    11701 ttctttattt tgtaaaaatc ctatcacttg attttatggt aaccttttat ttttgtcttc
    11761 aaacggcttg gtaagagagc agtaagcagt gcaaatggga tcgaaaagac ataccagaaa
    11821 atcgtacgtc cgataccata atgttgatag agctttgtca acatcacgtg taacaagatc
    11881 aaccctaaaa gcaaggagcc agctataaac caatggttat cccaatgcat gacttcacta
    11941 agtgccatca ctccaaaagg atagaaataa aaatagatcc cgactaaggt catccgccag
    12001 ttctttgtaa atgttccgat attcaataaa aagaaaatcg ctgaaagcaa aataccgata
    12061 ggcggaaaaa gcccaaccaa aaaggaatac aacatccccc acaagatcat cacaggacct
    12121 ttgatcaatg caacgattgc gatgaacaaa gtcagcaata ttagtttttg tgataacgtt
    12181 gcaacagtca ttaatccaaa taaaattaat gtgaaccaat gccaatggga ctgctgttgt
    12241 tctttacggg aaaaatcgac ccggttggat aaataatctg ctaatttcgg ataagaacgc
    12301 ttaaaatcca taaactgttc ctccttcgtg gaaaaggtag gtttagtata cgaaaaataa
    12361 aaaagaaata catccgtctt aagagggagt ttttcactga aagtggagaa aaaagaatgg
    12421 taaattaaaa tattctcagt tatactgaaa attataccaa atttcaaaga agaaagagga
    12481 tgggaatgaa aggcaaacta aaacgagaaa tcaatctgtt tggcgcatta gctaccgtta
    12541 tgggaaccgt gatcggtgca ggcgtcttct tcaaaactgc tgctgttact gctagtactc
    12601 agtctacaag tttgacattg ctagcttggc ttttgggtgg tttcttaacg atctgtgctg
    12661 gattgacagt ggctgaatta gctacagcaa tcccggaaac tggtggagct gtaaaatata
    12721 ttgaagctgc gtatggaaaa ttgcccagct ttttattagg atgggcgcaa agcttgattt
    12781 actttcctgc taatattgct gcattatcga ttatctttgc gacacaattg acgaacttat
    12841 tacaattatc taccgattat cttttgttga ttgcagtgat caccgctgtt tctgtgacag
    12901 ggttgaattt gttagggaca aaagtcggtg cttctgtaca atcagtgacg ttgattgtta
    12961 aattaatacc aattgctgtg attgtcatat ggggattatt gaccccagga caaggaactg
    13021 tccagttatt tccaatcgaa gctggaaaag atgttacttt tgtcgaagga ttgagcagtg
    13081 cgttgttagc aacgttgttt gcttatgacg gctggttagg tgtcggtgca atggcagggg
    13141 aaatgaaacg gccggaaaaa gatttgccta aagcaattat tcttggtttg agttttgtaa
    13201 cagtcgttta tctattgatc aattttgttt ttttgaaaac tttgccgatt gatcatcttg
    13261 ccggtaattt gaatgcagct tctgaagcat cagacgtcat ttttggagga atcggtggaa
    13321 agctggtcac tattgggatc ttgatctcgg tatacggtgc attgaacggt tatacactaa
    13381 ctgggatccg cgtgccttat gcgatggctt tagaagacga gctacctttc agtaaacagc
    13441 tgacaaagct ttcaaagaag tttacggttc cttatgttcc tgcggttttc cagttagcag
    13501 tagcttgtat tatgatgagc cttggttctt tcgacttttt aacagacatg ttgatttttg
    13561 tgatgtggct attcagttta ctgattttta tcggtgtctt tattttaaga aaaaaagcgc
    13621 cggaattgcc acgtccatat aaagtaccac tttatccaat cgttccgatt attgcgattc
    13681 tcggtgctat tttcatttta ggtatgacga tgatgacgca aacgaaatta gcattgatcg
    13741 gtataggtgt taccttgata ggtatcccag tctattatca aaaaaagaaa aaacgctcag
    13801 aagagtaaaa tatttcaaca acagacagaa aaagtacgaa ctaggtcctc tagatcttcg
    13861 tgctttttct atttcaataa aacaagttct tctattttga tttttgctac ttctgcaagt
    13921 agtgcttatg tgctaaagta agaatgaaaa ggagagataa acatgatatt tgattctcat
    13981 acccatttaa atgctgaaca gttcaatgaa gatattccag aaacgattca gcgagcacaa
    14041 gaaatggggg taacgaaaat ggcggtcgtg ggcttcgata cgccaacgat tgaaaagtct
    14101 ttgcaattaa gccatgacta tccaaatata tacagtatta tcggctggca tccgacagag
    14161 gctggcagtt atacgaaaga aatcgaaaat aaattacaag aacaattgac tttaccaaag
    14221 gttgtagcat taggggaaat tggcttggat tatcattgga tggaagaccc gaaagaagtc
    14281 caagataaag tatttcgcag acagattgct atcgcaaaag aaatgaacct accaatcagt
    14341 attcatacta gagaagcact tgaagacacg tatcaaatcc taaaagaaga agatgttcga
    14401 gatatcggtg gaatcatgca tagtttcagt ggtgattatg aatgggcaaa acgatttctt
    14461 gacttaggga tgcatatttc atttagcggt gtcgtcactt tcaaaaaagc attagacgtc
    14521 caagaggctg cagcaaatgt accaatcgaa cgattacttg tggaaacaga tgccccttat
    14581 ctggcaccag ttccttttag aggaaagcga aatgaaccag gctatactcg ttatacagta
    14641 gaaaagattg ctgaacttcg gaatcttccg acagaagaag tggctgccca aacatggaca
    14701 aatgcgcacc gattatttgg tctaagcgaa catggataag atgaagatcc aagagattat
    14761 agtcgttgaa ggaaaagacg atacaagaag gctgcgggaa gtagttgatg cagatacgat
    14821 agaaacaata gggtctgcaa tcaatgaaga gatcctgatg caaattgaac atgcccaaga
    14881 gactcgtgga gtgatcgttt ttaccgatcc tgatttttca ggagaaaaaa taagaaaaat
    14941 cattatggaa gctgttcctc aggcaaaaca tgcttttttg ccgcgcacac aagctaaacc
    15001 aaagaaaaag ggaagccttg gtgtcgagca tgcaagtgat gctgctattt tagaagcatt
    15061 gaaaaaggtc gtgacgccag acatttccca aacggctgtt tctgaaatca ctagacaaga
    15121 ccttttagac tatggtttaa tagctggggc acaagcaaaa gaaaaacgag aaaaactagg
    15181 tgacgagttg cgcatcggtt acacgaacgg caaacaattg gaaaaacgtt tgaagatgtt
    15241 tcgtattacg ccgaaagaac tcgcccaagc aatgaaaata gtggaggaac aacatgagtg
    15301 aatatcgtga aattgcgaca ccctctagaa caaaagagat tttattgaaa catggttttt
    15361 catttaaaaa aagtttagga caaaattttc tgactgaacc aaatatttta aggaaaatcg
    15421 tagaaactgc gcaaatagat gaacatacga acgtgatcga agttggacca ggaatcggtg
    15481 cattgacgga acaattagcc aagcatgcaa aacaagtcgt agcatttgag atcgatgatc
    15541 gtttgatccc tgtattggct gatacgatgc aaccctatga caatgtgact attgtacatc
    15601 aagatatttt aaagaccgat ttgtcaacag ctgttagaga aacatttcat gaggagcttc
    15661 cgttaaaagt cgtagcgaat ttaccttact atattacgac accgatcatg atgcattttc
    15721 ttgaatcaga tttggttgtg gatgaactag tcgtcatgat gcaaaaagaa gtagctgatc
    15781 gtatctctgc tgaaccagga acgaaagctt atggttcatt atcgattgct gttcaatatt
    15841 atatggaagc cagtttagca ttcatcgtac caaaaacagt atttgtccct cagccaaatg
    15901 tagattcagc gattttgaaa ctgacaagaa gagatatacc ggcagtcgaa gtgacagacg
    15961 aaaaagcatt tttccgattg acaaaagcgg catttcagca aagaagaaaa acgctttgga
    16021 ataacttgca gcattcgtat ggcaaagatg accagacaaa agcatggtta gcaaaaagct
    16081 tggaaacagc tggaatcgat ccaaaacgtc gtggggagac tttgtcatta caagaattcg
    16141 ccgcattaag caatgcgatg tcagaaaata tgcagtaaaa aaagaggttg tgacagaagt
    16201 tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca aacaaaaata gttcctcatg
    16261 tttttcgttt gtttgggctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    16321 aggttgtggg cctgccgttt aactctaagt cacaaggaac aatttcaaaa aacagcttct
    16381 catgtttttg agttagttgg tcttattact tgatgcaagc ttttgaccac tattatgccg
    16441 aacaaggaga tgtgacacaa attttgtcac atctcctatt tttgtttctt gatcaaaaaa
    16501 ttcttatact tgatactcac actcattttg tatggattta gaaaagaata tgtgtcttga
    16561 cagttattag taagtgagtt atactaagtc gacatttatg tgtcaagaca tattaggaga
    16621 gagaaaaaat gagaaaaaat tcagttcgaa aactaacgat ttctgcttta ttgattggga
    16681 tgggggtcat tatcccaatg gtcatgccta aaatcatgat tccaccagct tcctttactt
    16741 tggcgtctca tgtgccatta tttattgcga tgttttttac accaggagtt gcagtggctg
    16801 ttgcgctagg tacgacattt ggtttctttt taacaacgcc ggttatcatc gcattgcgag
    16861 cattgtcaca tcttgtgttt gcgttgattg gggcttggta cttgcaaaag catccgagta
    16921 tcgttttaaa aaatggacag tttacttttg ctaattggcg tttccaaggg ttcaattttg
    16981 tgatcggtgt gattcattct ttagcagaaa tgctagtagt cagcatcttt tactttattg
    17041 gtaatatgcc tgaaacatat tattctcaag gatattttta tacagtattc atcttgatgg
    17101 ggattggtgg gcttatccac agtttagttg attataatat tgcttatttt atagcaggaa
    17161 cactcagcaa atattttgat atccccgtat ttacggcagc aaaaaaagaa aatcggaaag
    17221 agtcgattca agggtacgcg aagaaaacga catattagac atgatctctc aaaaaaaaaa
    17281 ctctcatcta gtaatggata ataaatcctc taagatgaga gttttttgtc ctaaaaagag
    17341 ctgcaccaac atcttctggc acagctctaa cagggggcaa tttatggaag tttgatgact
    17401 tgttctgttt ctttatcaaa gaagtggcct ttgctgatgt tgaaggcaag gtcgactatt
    17461 tcgcctggtt tatggaaatc tcttgcatct acttttgaga tgaactcagt agaaccagtt
    17521 tttgtgtaaa gcatcgtttc agctccaagt aattcggaaa cgacaacttc tgatttcact
    17581 acggcttcag gtgaagcttc aagggctact tgttcactgt ggatgtcttc tggacgaata
    17641 ccgaagataa cttcttttcc ttcataacct ttttcaacta atactttgtt ttttccttca
    17701 ggaatacgaa gcttaagccc atgtccatct gtgataacac catttttcaa tgtcacatta
    17761 aagaagttca tggcaggaga tccaataaag ccggcaacga acatattgac gggtgtatca
    17821 taaacttctt tcggtgtacc gatttgttgg ataaatccgt ctttcatgat aacgattcgg
    17881 tcagccatag tcattgcttc tgtctgatcg tgagtaacat agatggtcgt tgtttcaaga
    17941 cgctggtgaa gtttggcaat ctcagcacgc atggctacac gtaatttagc atctaaattt
    18001 gataatggct catccattaa gaagactttt gcatcccgaa cgattgcccg tcccaatgcc
    18061 acacgttggc gttgtccacc agataaagca gctggttttc gtttcaagta ttctgtcaga
    18121 cctaagatct ctgctgcatt gtccacacgt tttttgatgt ctgctttatc atatttacgt
    18181 aatttcaagc caaaagccat attatcaaaa acagtcatat gaggatacaa tgcgtagttt
    18241 tggaaaacca tggcaatatc acggtcttta ggtgccacgt cattcatgac ttttccgccg
    18301 atatttagtt ctccttcaga gatatcttcc agtcccgcga tcattcgcaa agtagttgac
    18361 tttccacaac cggaaggacc aacaaaaacg ataaattcac ggtctttgat tgatagatta
    18421 aaatcagtta cagaataatt ttctgcattg tcatattttt tatatacgtt tttcagagcc
    18481 atttctacca taatacgttc cacactttct tttttagttt tattaactat ttaaagtata
    18541 aatgaaagcg ttaactaact tcaatgtcat gttgaacaag aattttttct tttttttgtc
    18601 aatgtgctag ttttaagctt taataaatat ccataagaaa taaaaactga tacactggag
    18661 taaataagta tgttaacaat atcaaaagga gtgtctctta tgaaaatcgc tttgatcgct
    18721 catgaccgaa aaaaacctat gatggtgaaa ttagcaacag cgtataaaac aatattggaa
    18781 aaacatgaac tttttgctac cgggacgact gggcagagga tcacggaagc aaccggcttg
    18841 ccgatccatc ggtttaaatc cggaccgtta ggcggggatc agcaaattgg agccatgatt
    18901 tcggaggatc agttagattt ggtgattttt cttcaagacc cgctggctgc acagccccat
    18961 gaaccagatg taacagcact tatccgttta tctgatgtct atgagattcc gttagctacg
    19021 aatatcggaa cagctgaggt gctactaaga ggactggaag ccggcttcct agattttcga
    19081 agaatcgtcc atgaaataga caagcatcca ctttcatttt gatggataag cgtatggaaa
    19141 aataacgttt aatgttcgcc tatatgtagc tataaaagct aaacaaactg ataatatgcg
    19201 atataatacg aacgtattgg ataatataaa caataatatt agtttttcgt atttgcagta
    19261 aatgtgaaaa tatgctatag tttctgtggg aaaagatccc aaaaataata cagagtagaa
    19321 aataaagcgt taagtgctaa gaggatggga tgttgcctct tggacgaagg acgtaatgtt
    19381 cgcggtttta ttttcgcatt cgctgcatga tacgatgtag cagctcttaa aggagatgct
    19441 aaaaatgaag aaacaccggt tagacgcacg tatgattgct attatgggct tattgattgc
    19501 attgatggtc actttgtccc gactggtagc aatcgagacc ccatttatta aaatcagtgt
    19561 cacatttatt ccacaagtga tcatgggcat tctttttggt cctttttggt cagggatagg
    19621 cgcagtttta gctgatttag taggaatggc cctcttctcg aaatctgcat tctttattgg
    19681 atttacattg aatgcattta ttgaaggagc aatctacgga ttctttttct atcgaaaaga
    19741 gatcacttgg aaaaatgcca ttctggctac gcttagtgtc acgctgatca tcaacttatt
    19801 tttgacacca ttatggcttg cgttgatgta ccatgtgcca ttgttcagct gggtcgtttg
    19861 ggcgccccgc ctgttaaaaa cagtaatatg gttaccgatt caatcaattg ccatttatta
    19921 cgtaggacgt agtattcctt acaaaaaaat tttaagaagt ttagcgatcc acgctaaata
    19981 aaaaacaagc agtcttccca tcccagaaga ctgcttgttt ttattgtgct gtgaattgtg
    20041 cttgatagag ccgtcggtaa taaccatctt tttgaagcag ctcatcatgg gtgcccattt
    20101 cgacaatagc tccctgatcc atcactaata tctggtccgc atttttgatt gtggacaggc
    20161 gatgggcaat cacaaaactg gtttttcctt ccatcattgc taagaaggct tgttggattt
    20221 ttttctctgt caatgtatcg actgagctgg tagcttcatc taagatcaac atagggggat
    20281 tactgatcat cgttcgagca atcgtcaaca gttggcgttg tccatctgat atctttaacc
    20341 cttgaccgcc aatcttagta tctaattttt ccggcaaacg ttctacaaat tcatacatat
    20401 aagaggcttt tagggcatca ttgatttctg cgtcacttgc ttccggattc ccaaaacgaa
    20461 gattttctcg caatgtactg tcaaatagcc aagtatcttg taacaccatt ccaaaacttt
    20521 tacgtaatgt atcacgttgg atagagcgga tgtcatggtc atcgactgta attgttcctt
    20581 ttgttgtgtc ataaaaacgc atcagcaaat taacaagtgt ggattttccg gcccctgttt
    20641 ttcctactat agcaatggtt tgacctggat aagcagtaaa attgaaatct tcgatcaaac
    20701 gctgcttggg gtcataagaa aaagaaacat gatcaaaaga gacttttcct ttgatatttt
    20761 tgggttccaa ggcataggca tctggcaaat caggcttttc ttctggctga tcgatcaaat
    20821 caaatgctcg ttctagacca gaaaaagcgg tttgcagttg tgtcgtgatt ccagaaagtt
    20881 cgataaatgg tttagaaaac tgacttgagt agatcgtaaa gctggaaatc acaccaacag
    20941 tgattgacga accactcttc aatgccaata ggccgccaac taaaccaatc gataaataag
    21001 caaggtgatc tacaaaacga gaagacgggt ttgtcaagga agaagaaaat tgtgcccgtt
    21061 gtcctttttc atatagatca gcatttagca gttcaaattg ctgttgacta gcttcttctt
    21121 gctgaaaagc tttcacgatt ttctggttac cgattcgttc ggtcacaaag cccgagatat
    21181 ccccaataat cctttgctgt ctatcgaaat ttgtttgtga agcacgagca acgatccaac
    21241 tcacaaggaa aataattggt gtagaacaaa gaacgaccaa tgtcagaagt ggacttagac
    21301 gcatcataaa aataaacgaa agaatgatga ttgccactcc agaaaataat tgattgaagg
    21361 ccgcagaaat tgcaatggaa atattgtcca tatcatttgt aaatcgactg acgatatttc
    21421 cgtgggagtt ttgatcataa taacgaagtg gcaatcgatt cagatgagca aatgcatctt
    21481 ttcttaattt tgcaacggat aagtaagcta accgattgct taacacttgg atgagccatt
    21541 gactgactac gttgattaaa acgataccac cgaatagaat aagtaaatgg aacagtcgat
    21601 tgaagcggac ctgtccttct ccaatcattt gatcgatact ttgaccaatt tgtaacgtca
    21661 tcacaactgt tgcaatccca ttgatgattc ctagtatcac agctagccaa atgtcttttg
    21721 cataggcagt aaggtaagga atgaatcggc ggagcgtctg caaggataat ttttttactt
    21781 tcataactat tcttcctcct gtgatgcgac gatttcctga tattctgctg attgagcaag
    21841 taattcttca tgggtaccct gagcagcaat cttaccttga tccatcacta agatatgatg
    21901 tgcttcttga atagagcgga cacgttggga gataataatc actgtactgc caagataagt
    21961 ctgtagcgcc ttacgcaaat ccaagtctgt ttgataatcc aacgcactta aagagtcatc
    22021 taaaatcagt aatgctggct tggcaatcaa agctcttgca atcgtcagtc gctgtttttg
    22081 tccgccagag aaatttttcc cattttccat gacttttgta tctaaaccat ttggaagctg
    22141 acggacaaat tcttctgcct gagcgatttt cagagcttcc caacattctt tttctgtggc
    22201 gtctttctta ccccattgaa ggttttcacg aatagtcccg gtaaatagta cagaagtttg
    22261 gggaacaaga gcaatttgct gacggagatg atccagctgc caagaacgaa catccattcc
    22321 gtccattata actgtaccgg aactgacatc atagaaacgc ggaatcaatt gtgtcaaagt
    22381 cgttttcccg cttccggttg gaccaatgat tccaaggact gtatttcgct tcagctgaaa
    22441 tgtaatattt tggagagaaa gaccagaatc aggagtataa cggaagtcaa catggtcaaa
    22501 agcgataatt gcttcagaag aaaaatcggg agtagtactg acctcagctt caagaatcga
    22561 attttctgtg tctagcacct ctttcacccg atttcctgaa gcttcggcac gtgtgaagat
    22621 cacgacgagg tttgaaacaa cgatcagtgc caaaagcatt tgattcatat aattgatcaa
    22681 agcaagaact tgtccttgtt gcaagctacc aatatttact ttgatcccgc caactgtcag
    22741 caaacagatg atcccgacat tcatgatcaa ggttgtagca ggtgataata gggcagagat
    22801 attggaaaca cgtaaataat tgttcgctag atcatttgtg cttttatcga acttctctgt
    22861 ttcttttttt gtctgcgcaa atgcgcggat gacacgaaca ccgctaagat tctgactaac
    22921 gtgttcattg agctgatcta gtttttcttg cactttttgg tagagaggaa cggttttttt
    22981 gatgataaaa aataaaatga ttgagaaaat aggcaataat gctaagaaaa acagacctac
    23041 ttcccagtcg atcacaaaag ccatgaccac tgacccgata cttaaaaacg gtgctctgat
    23101 caataaacga atgaccattg ctaaagctag ctgaagctga ttgatgtcgt ttgtcattcg
    23161 ggtgatcaag gtatctgttc caaaatgatt caactcgttg tgagagaaag tattgatttt
    23221 tttgattagc tgattacgta actctgtacc aaatccttgt gaagctactg aagcatagta
    23281 ttggcaaatg atagcacaaa tcagaccaat cacagacata gcgaccatcc ataagcccat
    23341 ttcaatgatt tttcctcggt cattcatttt tagtccatta tcgatcaagg aagccatcat
    23401 taaaggcagg acaagttcga agacagcttc aagaaatttg aagaacgggc ccaaaatgat
    23461 ttgcttacga tagtcttttg cataacgtaa taactgaatc atatgattcc tcctattatt
    23521 tatttgtcca caattgaaaa aacaagtact accacattgt agcttaggaa atttagaatg
    23581 aaaagagaac aagccttttc ataaatgaaa gttttattat gaagaagctt tagaaattga
    23641 atagactatt ttttttaaaa aaaagaaaat gagaaaacat gccagtctct tcattcatag
    23701 gaacgtctat tttacttaat ttttctataa atgaattctg cataaaaaat atatcaagta
    23761 aatgtttata gatgaaactc tatttacttc ttttttaatt tgttcttgca atcttttttg
    23821 ctacgtaatt tttgtaaaaa agtgggttga gagaaatcta attgattttc aaagaaggag
    23881 tatgaaaatg agaaaaatat ttattcgttt attgtgggta ctatcttaga ggaataaata
    23941 atagtggaga aaactatggt ttggcgcaga ttctatcagg tttgatggaa cgaagacaac
    24001 ctcccgacat caagtcaaaa gctacttgag attttgatct gaaaataaaa aaagaaaaca
    24061 aggtaggaac atcaatgttt ctaccttgtt ttcgtaatca atgggaaaaa actaagagtg
    24121 gtgtacgtaa tcaataaaaa ggatggtgac aacagtacct ctttactctc tgaaagcatc
    24181 ataactcgtt tttcctcatt atgccaataa attgttgtta taccacatat aaggatttgt
    24241 aatagctaaa aacagacagg aaagttgaaa tctgtgaatc ttattttgta tggaaggatt
    24301 tatagaacgc aaaaatcaag ataaagatga ataaaaatcc tgtttcggct atatattgcg
    24361 tatctacgcc aataaaacga gtttgttctg tcatagccat ataaagcaaa ggcaaaaata
    24421 caactacagc gagataagat ccgatgattt ctcgaaaagt tttccaggaa gtatgtttcc
    24481 tgtttttata tttatccgat ttcattgaat agtcatagcc tccttattct ttcatatgtt
    24541 gaaattccag tataaaaact ggaaggaact gtacgttttt tagaataaaa attataaggg
    24601 ataagtaggc tgctgtctat aataagatat atttttcaat tctttattaa agattttatt
    24661 gacaaaatga atccgttttc tatgatggag gaggggtgaa taagttgttg aagaaggaaa
    24721 ttttatgtta cttagagaac cagacagcct ttttcgattt agaacatatg aacgaggtct
    24781 ttacagcaca aaggttagct gatcattttg gggtaaaaag aaacacagtc agtcattatt
    24841 tgaaccagtt aaatgatgag caactactag tcaaaatcaa ttctcgacca gtgatttatt
    24901 tccacaaaga agcttttgaa aaacaatttt ttaagttacg cacgaatttt tatttttcta
    24961 tcgatgatct caaagaggaa cagccttttt tcgcgcaacc aaaagactta ttctctttta
    25021 tgatcggata cgacgccagt ttgaaagaaa gtatcgaaca aatcaaaaca gctctttact
    25081 atccagatgg cggattacca cttttgatta caggcgaaag tggcacaggt aaaagttatt
    25141 tagttaattt ggtctatcag tattgtctgc ttcatgatct gctagaagat tctgcaccat
    25201 tcatcacttt taattgtgca caatatgcag ataatcctga acttttgact agcaatttgt
    25261 ttggacatgt taagggagcg tacactggtg cagaagaaaa taaaaaaggg gcttttgaag
    25321 cagcagatgg tgggatcttg tttttagacg aggtacatcg cttaacacca gaaggtcagg
    25381 aaaaactgtt cacctatctt gatcaaggtg tgatttatcg tatgggagaa cctaatttgt
    25441 cacgccggat caaaacacgt ctcttttttg ctacgactga agagattact agtcatttct
    25501 taacaacttt cattcgaaga atacctatcc gaatcgaact acctgcactt aatcagcgta
    25561 gtcgtaatga acggctagaa ctgatttact ctttttttct cgaagaacaa agaaaaatgg
    25621 ggagcccttt gtcagtcagt ggaccagctt tgtcactttt aacaagtcag aaattatccg
    25681 gaaacatagg agagctgaaa aatatcgtca aagtttcagc agcaaaagca tatgctgaac
    25741 agcgtgaaca gcctgaaatc catgtcacga tccatcattt gcaaaaagaa ctacttgcgc
    25801 agcctattac taaaaataca gcacagcaag gaatctatat tacgcaagac cagaccttag
    25861 agcaattaat ggagaagcaa cagcccgaac agcagcgaat cgttaaaagt tttgagcaaa
    25921 tcctaattga tttcaagaaa aataactgtc tgctatattc ttgcgaagga aaattaaagc
    25981 aagaagtgat tcaattattt gattttttgc tgtttgagac cagtagacaa gaaaaacacg
    26041 agctgctggt ttattggaca caatctatcc gagagacctt tcgacaaatg gaaactgcct
    26101 atcaaatcaa attcgatgga aacagtgtct atgccttgag ttactatctc tatcagcgaa
    26161 gcactatcaa atggttaccg gaagaacatg atattatcca actaatcaaa gaattagaac
    26221 aacaagtttc tcagtcttat ccatctagtt atcactatgt ccaacgaatt ctggaattaa
    26281 gtaagatcaa attagatatt gaagacacaa gtatggatcg gattttactg acgatctatc
    26341 taaaaaaagc gaaatggtca aaagaaaaac gactgccaaa agcgatgatt gctgctcacg
    26401 gttatgcaac tgctagcagt atggcaaatg tagtaaatcg tttattacaa gaggatctat
    26461 ttgaatcatt tgatatgcca ctagatgtca caccacagca gattgcttca gaaatccttg
    26521 attattgcga aaacagcgat gtttcaaatg gattgatcat attagtagac atgggatctc
    26581 tgaaagaaat ccatcagttt tttaaaaaac agttatccgt accgcttttg attttgaata
    26641 atgtgacgac acctttagca atcacagtag gggaatgcct gcaaaaaaat gtatcattag
    26701 aagagatagc agaagagact gttcgacaga tccagccaga atggcgactg ctctatccag
    26761 aggaaaacaa acccaaagca ctcattacta cttgcttcac tggaatcggt acggcggtcc
    26821 acttaagtga actgctagaa aaaagcttac ctacggcttg tcagttgaaa atcatcccat
    26881 atgaatatca gcaattaaaa gataagaaaa acagtgaccc attattttcc atatacgaag
    26941 tcgtaggaat gattggcacc acagatcctg atatcaccaa tatcgactat ctttcattag
    27001 aagacctcat ctcgggggaa aagatgtctg tactagctga atggttggac actactatga
    27061 atgcttcaga gaaggaaata ttcaatcagc gcatcattcg taatttttca ttggaaaaag
    27121 tactggattc cgtgactatt ctagatacag agaaggtgat gggagaaatc gatcatttta
    27181 tgagagaatt agaggtgcag ttgaatcgaa gcatcagcaa tcccaaaaaa ttagcgttgt
    27241 atgtccatgt gagctgtctc attgaacgat tgatccgaca aatgccaatc gaaacctatc
    27301 aaggattaga gaaatggaag cagtgtcaaa aagaagggtt atctgctatt aaatctgcgt
    27361 ttagtgtcat tgaagagcat tatagtgtca tgatccccaa ttctgagatt gcctatatct
    27421 atgatatttt gagtgaagat acagagtttc tctcgataga agaagaattt tgaacataag
    27481 caagttgttg ccactaattt tggcatgcaa cttgcttttt tagtatgtgt aagtgaaaag
    27541 aggagatgaa aaagtggata gagaaattat cttagcttcc catggaaaat ttgcttcagg
    27601 gatattagat tcattagagc tgatctatgg gaaaaatcat tctattactg tattcgattg
    27661 ctatactgat gagaattttg atttagcgga aacagtaagg cagcttttta tgaggtacaa
    27721 agataaagaa atcattgttc tgacggatct ttttggcgga agtgtcaaca acgaattctt
    27781 acaatatatc aatcgggatc atgtctatct cgttgccgga ttgaatttgc cactattgat
    27841 tgagctagta tctcggttgg acgctgaagt agagacaact gttttgatcc agcaggtgct
    27901 aactgattca aaaaaaatga tccagttttg taacgagcgg ctcaatcaga aaatagaaga
    27961 agacgaattt taggaggaag aaaaatgatt gtattgacaa gagtcgacca tcggttatta
    28021 cacggacaag tagctttttc atggacacaa acaataggcg cagactgtat tttgattgct
    28081 aatgatgatg tacctacgaa tgagatacga aagacaacga tcaaattagc caagccacaa
    28141 ggagtcaaac tagtgatcaa atcaattgat gactcgattg ccgcgttgaa aagcggggtg
    28201 acagataaat ataagttatt catcgtagtg gaatcgatcg aggatgcata taagctggca
    28261 gaagcgtatc cagaaatcaa aaccatcaac ttaggaggga tcaaggcaaa acctggtact
    28321 cgcagcatcg gaaaagcggt aaatatttta ccagaagagg aggaacgctt gaaacgatta
    28381 attgacaaac aaatagaagt agaaatccgt caagtaccag cagataaaaa agtggatgta
    28441 agagaagttt tgtaagaaag gaagaacctc aatgattgta caagcagtct tattaggaat
    28501 tgttgcattt gtcgcacaat cagaatatgc actagggaca tcgttgcttt ctcgtccgat
    28561 tgtgacgggg ctgtttacag gaatcgtgtt aggtgatgta aaaactggga tcattatggg
    28621 cgcaacttta gagttagcat ttatcggatc gttctcagta ggtgcttcga ttccacctga
    28681 tgttgtgacc ggtgggattt tagggacggc ttttgctatt acagctggag ccggtacaga
    28741 aaccgcgctt ttactaggtt tgccgattgc tacgttgaca ttgatattga aaaatattta
    28801 cttagggctt ttgattccaa ttatgaacca taaagcagac aattatgcag aagaaggaaa
    28861 ttataaagga gtcgagcata tgcacttgct tgccggtatc ggtctttcct tgatgcttgg
    28921 tgttgtggta atggtttctt atatggtggg aagcaatacg atcggaaatc tattaaatat
    28981 gattcctgac ttcgttcaaa aggggttgtc agtagctaca gggttgattc cagctcttgg
    29041 ttttgcgatg cttgctcgtt tgctgatcaa caaacaagtt gcaccatatt ttttcttagg
    29101 ttttgctata gcttcttact tagagattcc tgtgaccgga gtagctattt ttggtgcgat
    29161 tttagcagtt gtggtagtca atattatgaa tgtccgtcaa ctaccacttc aaacaactgc
    29221 aggggaggta gaagaagatg aagaattctg agatcaaaaa cagcaaaata acgaaaaaag
    29281 agctaaatca cgtattttgg cgttcttttc aaatggagtt ttcttggaat tatgaacgtc
    29341 agatgaatat ggcttatgtt tatgcaatga ttccgatttt gaaaaagtta tatcagtcga
    29401 aagaagaaat ggcagcagct ttgaaacggc atctagagtt ttttaacacg accccacata
    29461 tcgttacact gattttagga atcacggctg caatggagga agaaaataag gatgatcctg
    29521 aatttgatgt gactgcgatc gatagtatca aaacatcttt gatgggacct cttgcagggt
    29581 taggagattc tttcttttgg ggaactttgc gattgattgc cacaggtgtg ggtacctctt
    29641 tagccatgca aggaaatatt ttaggcccta tcttgttcat tttgattttc aatattccgc
    29701 acattctgtt tcgctatcta gcaacaggtt ggggatatcg cttaggaacg ggttttttga
    29761 aaaagatcca ggcaaacggt atgatggaaa gtttgacatt aggcgcgtct attattggac
    29821 tgatggtcgt tggagcaatg actgccacga tgatcaccat caatattcct ttaaaaatcg
    29881 gttcaggaga aaatgctgtg actgttcaaa gtatttttga tgatatcgtt ccaaatatct
    29941 tatgtcttgg agcatttggc atagtgtttt atctattgaa gaaagaagtg aaaccattaa
    30001 cgatcttgat cggactagct ttctttggaa tttttggttc gtggataggg attttttaaa
    30061 aaaggagcag agaaaatgtt tacgatgcaa gattatatct atgaagaaaa ggaagtacta
    30121 agtacgatct tgaaaaagaa tgatttttcg acaagagaac atatgaaaaa aacagtgaat
    30181 ttactgatct tagcaacggg ttcatcttat aacgcttgtt tagcagcgaa gccagcattg
    30241 gaatcttatg gtgatcttac tgtcgatatt caagaacctt tttatttttt caattatgga
    30301 aaactttctc cttcaatcga tactgtgatt gctgtgtcac aaagcgggaa aagtgcttct
    30361 actgttgaag cagtaaaaat gatacaaaaa caagggttac ctgttgttgc tatcacaaat
    30421 gacgtgcaaa gtccacttgc tttagaagct gcacaaatta ttgatttagg tgccggggta
    30481 gaatcagtag gcttcgttac aaaaggctat tctgcgactg ttttacagtt actactctta
    30541 gggataggaa ttggaataag taaaaataaa atcagcaaaa aaatagaaca agactacatg
    30601 caacagttgc gcaaaataat caaccattta ccagcgatta ttcaaaaaac ggaagaattt
    30661 tttgatggat atcaaagttt atttcgttta gcacagcgtt tcgtcaccat tggatatggt
    30721 ccaaactggg gaacagctaa agaagcagag acgaaattga ctgaaacaat ccgcgttccg
    30781 tcacaaggat ttgagttaga agcttatatg cacggcccat acctggaggc agatgcttcg
    30841 catttgctat tctttattga aggggaaagt gtaaataagg aacgttcgca aaagttgcaa
    30901 agatatatga gtcggtacgt tggagagact ctcaccatta ccacaaaaaa agcaagaaac
    30961 gagaaaacac ttggattagc aatagaatgt gatgaatatc tgtctgtatt agcgcttgtc
    31021 gttccgtttc aactattcgc ttataaaacc gcagtagcta aaggtattga cttgaacaaa
    31081 aagatttttg aagactttga tacagtcttg aaaagtaaat tataagaggt ggaaatcatg
    31141 ctgaaattca atgaagaaga acaaatcaaa gcaataaaag gcgcactagc tttacgtccg
    31201 caagtagaag aaatcatcga taaactttat gcggaaaaat ttgacgctgt ctattatcta
    31261 ggaatcggtg gaacgtatgc ttcctcgatg caagctgtca cttatatgaa tgggaaaagc
    31321 aacttgcctg tctttgtaca gcatgctgca gaatattaca ctactggaaa caaaagatta
    31381 acaaaagatt ctatcgttat tttgtcctct gttaccggta caactcaaga agtagtgaaa
    31441 gcagtagaac aaatcaagaa agtaggagcg acactgattg gatttatcga taaagcgaac
    31501 agtaagttgt ctcagctatg cgattttgtg gtcacttatc cagctcctgg aacagaacaa
    31561 atcaaatttt ttatggcagc agatcgattg atgtatttga atggagaatt cgaagcttat
    31621 tcagaatact atgaacagct cgaacgttat ttaccaacag ggttagtgga agcagagaaa
    31681 aaagcagatg catttggctt atcatttgca gaaaaacatc gacgtgatag tatgcattat
    31741 tttattggag cagggaatca atggggagct gtttattcat atgccatgtg ttactgggaa
    31801 gaacaaagct ggcttccatc gaaatctatc catgctgccg agtttcttca cgggacgtta
    31861 gagatcgtag aagaaacaac cccagtcaca ttatttttag gcgaagatga acagagagtg
    31921 ttatctgaac gtgtggctaa acttttgcca aaaatttgca gcaattatac attgatagac
    31981 acaaaagact atccagtaga aggtatcagt gaaaaatatc gcggacgtgt tttgtctttc
    32041 ttattgatgc atgtagtgac acaacgcatc gatgctcatg tggagcagtt gaactgccat
    32101 ccattagaga tacgccgcta ctatcgtcag tttgattatt aggatagact ggataaaaag
    32161 aatataaaaa ataaagagag cagcgataac tgctcccttt atttttttaa aatattggca
    32221 tcaattacgt tataaaacac attttttgca ttatctacag ttcaacttat aatctgttta
    32281 atgggacatg tgggtgccaa ccattttttg ttatgcaata gtactattta gttgttgcat
    32341 ggatccgtag taaaagtcca agtacaacga gttgcgccag tttacatagc gttttgtatc
    32401 cagaatgttg actaaaacaa aagttcctat gtcaaccgtc aacagagaca atctgtccgt
    32461 tgcaggacct gacagattta gaaatgttca atctgtctct tatgtatttt aaatcaatac
    32521 tcactaggag aagtttccta acctcctaat agtaatgctg gtagtaacat tgtcaaaact
    32581 gcttcctctt aggaacaagc aaagcataac gagtgtaaaa ataaaatgta gactattgta
    32641 acatatcatt gattatttca agtaaaaacg ataaaagaag taaacaaaca cttaaaaaca
    32701 atggaaatta gtcccaactt taagaaatgt atactataat ggaaattatc aattatttat
    32761 ttggaggaat atccatgaaa caaaaaatcg cagttcttgg tcctggatct tggggcactg
    32821 ctttagcaca aacattggca gaaaacgggc atgatgtccg tatttgggga aatgtacctg
    32881 aacagattga tgaaatcaat aagtatcata caaatcagca ttttttacct gatttgacga
    32941 tcccagaatc gattatcgga tataaagaat tggcagaagc agtggataac gcagatgcta
    33001 ttttatttgt tgttccaaca aaagcgattc gttcagtcgc acaggaactt attggtaaaa
    33061 tgaatactaa gccaatcatt atacatgcaa gtaaaggact agaacaagat acgcataaac
    33121 gaatctcaga agttttggct gaagaaattc cagaagaaaa aagacaggca attgttgtat
    33181 tatctggtcc tagccatgct gaggaagtgg cagtacatga tatcacaaca attacagctg
    33241 caagtattga tcaaaaagca gcagcctatg tacaaaaact gttcatgaat gattatttca
    33301 ggatttatac aaataatgat gtgattggcg tagaaactgg tgcagcactg aaaaatatca
    33361 ttgcaattgg tgccggcgct atccatggat taggattcgg agatgatgca aaagcagcaa
    33421 tcatgactcg aggattggca gaaatcagcc gtcttggtgt cgcgatgggt gccaatcctc
    33481 tgacatttat cggtttgagt ggtgtggggg acttgatcgt tacttgtaca agtgttcatt
    33541 ctcgcaattg gcgtgccggt aacttgttag gacagggaca taagctggaa gaagttctag
    33601 aaaacatggg aatggtcgtt gagggtgtgg caacgacaaa agcagcagta gagctagctc
    33661 aacagctagg tgttgagatg ccaattactc aaacaatcta taatgttttg tataatggag
    33721 aagatatcaa aaaagcagca aaagaaatca tgttacgtga cggaaaaatg gagaatgaat
    33781 tttctcttcg ttaaatagat gatcaatagt taatcgtcgt ttaggaggaa cagcaagtga
    33841 aggtcaaaaa agcagtcatt cctgccgctg ggctaggaac acgttttttg ccggcaacaa
    33901 aagccatggc aaaagaaatg cttccaatcg tggataaacc aacgatccag tttattgtgg
    33961 aagaagcatt ggattcggga atcgaagaca tcttgatcgt aacgggaaaa gaaaaaagac
    34021 ccattgaaga tcactttgat gcaaatatcg aattggaaaa caatttgcgg gaaaaggaaa
    34081 aaacagaatt actcgcttta gttgaagaaa cgactcaagt caatcttcac ttcatccgtc
    34141 aatctcatcc aagaggactg ggggatgccg tgcttcaagc aaaagcattt ataggaaatg
    34201 aaccgtttgt cgtcatgctg ggggatgatt tgatgaaaga tgatatccca ttgactcaac
    34261 aattgatgat ggattatgaa gaaacacaag cttccgctgt tgccgtcatg cgtgtaccag
    34321 aaaatgaaac atctaaatac ggaattattg atcctaaaac agatagcgaa aagggtcgtt
    34381 gcagagtaaa agggtttgta gaaaaacctg aaatgggaaa agcaccaagt aatttagcca
    34441 ttatcggacg ttatctactg actcctaaaa tatttgagat attagaaact caagaaccag
    34501 gagcaggaaa cgagatacag ctaacggatg cacttcagac tcttaaccag acagaggcgg
    34561 tctatgcgag agagtttaaa ggaaaaagat acgacgtagg cgataagtta ggatatatga
    34621 agacaaatat tgaatatgga cttcaacatt cggaaattgg gacttcatta agtgcatata
    34681 ttatccagtt gagtaaaaag ctaagaacag aaagttaact ggaaataagt ggcctgctga
    34741 gaatgaaagg ctatttgtta ttaaagcggc agcttgtgcg tcatttgcgc aactgtcgtt
    34801 ttagtttttt gactctagat cagttgagtc gtggaaaacg aaagatagaa aaagactttc
    34861 gtgaatagat tcagaaaata ttatgctaat ggtttaattt ttttttaagt tgtataaaag
    34921 aaaatgatta cataagagaa atgaaagcca agccagaaga ttcatagtag aataaaaagg
    34981 cgaatttttt aattataaaa aaaggtgtgt gttcactatg ggaaaattag tcgctgttgc
    35041 acagtcgctg cttgatatac tcaagtggct gatggaagga agcaattgga tatttgtgtt
    35101 gccactattg cttattagtc tatttatcat gtttcgcatg gtcagaaaaa aagaaacgtt
    35161 tctgattttt atctggtatg cagcatccgt tggggttgct accttgatgg ttgaattggc
    35221 gttaggtagt tgggaagctt gcgtatttgc tttatttttt gctgtactgt atctaatcat
    35281 ttatatccca tatatgaaaa gaaagtctcg gataggcaga aaaggtagac atacaactac
    35341 tttttctagt acagattctc tcgaacaaag tagaagaacg agaagaagac ggtaatattt
    35401 agtaggtata cgcaaaaaaa gataaaataa tggataaact attgagatga gagatttatt
    35461 taattggtgg aaaaaagctt ttttcactta tataaaagaa tcttttttaa aggaatgctt
    35521 gttgtatcgg gataagccat tccttttttt atgttattta tatatatata aatcatacca
    35581 atgttttttt gtattttctt gcttgcactt ggataagaga ttacttacaa taaattcaga
    35641 tagaaacagc tgaataaaaa aaggctccct gacccttagt tggcgctaag aatcagggaa
    35701 tgaccagtca cacacataca ccctgaccga tcattttgcc atagtcaatg cagtgcatcg
    35761 acctaattta ttgtacctaa tctagggtga aaattctacc cctatgtaga tattttccat
    35821 ggtctgcacg ttgttttatt tgctatgtca aggtattggg cgtattcgtt caatgccttt
    35881 tttgtgtttg aaacagcaaa gaccacatgt gttactgtct aactactgtt tttttatgta
    35941 cttccttaga ttaggcagct gtttctattc atgtcaagta tagctaggcg ggagagataa
    36001 atgagtttat gttattttga ctattatcac caattggaag agaaattaag gatagaagag
    36061 ccgctgatgc ttcaagctgg cacttggatc gcgaaacaaa ttaatcaagg tggtagattg
    36121 cagatatatg ctagccgcac actaagtggt gtagcatttg aattttggga tcaaaccccg
    36181 gatcttgtac caagtatatt gattgaaaat ccagccggag gtgtctatga aacgctagaa
    36241 ggtgcaggac aggcaattat tgatcagctt tctgtcaaat cagaagacat ttttcttctt
    36301 ctttcgaatg aaggaagaaa cccggcaatc atcgaactag ctcagtggat caaagaaaat
    36361 ggtcatccat taatcattgt tactggattt gatttgtcac gaagtatcaa atcgcaacat
    36421 agcagtggtt tgcgattatt tgaatttgct gatttggttt tggacaacca cgccaattta
    36481 catgatgcag tcttgacttt gccaaatcta gatccagcga tctgcggaac agcctctctt
    36541 gcaacgatct ttttgctgca gcaagttttg tattttacag caaaacagct agtccaggac
    36601 acaagtggaa aatagttatc cacatgttga caaagttcct taaaaaaata atgttccaca
    36661 taaaaatgga gcgtttgaaa aaaagaaaac gattattaat gaggattaac aacgactact
    36721 ttttttgttt tagttatttt aagatggatc atctttgatt ttaagcttgt tttgtttaaa
    36781 gtttgttatt tttataagtt gtttcacagt tatgagaaat gagttataag aatatgtagt
    36841 gtcagaaaaa taaaaagtag tggaaaaaga gacaagaaag aatccatatg gattctttct
    36901 tgtctcttaa tacacgttga tgaaagagtc ttccccaaaa ctctttacaa agtaattata
    36961 gtacatttgt tatcattatt gcaatgaagt ttacctgata taacaaaatt gtccaacagg
    37021 ataccttttt ctaatagaaa taaaatacac aaaaattgaa ggatagataa tggatattta
    37081 taagtgttta ttattttttt tgcaatgaaa ttcaattttt caatgattgt aaaatgaaaa
    37141 aaacaggacg agattttctc taatctaaaa ataaaaaaag aattttaagg aaaaacagag
    37201 aaataaaata cttaatataa atggaaagag aaaaaaataa tcatacatag gagaaaaaaa
    37261 acaaaataga aaaaagtgat tttctaataa attattcatg tggaaatgtc atttttactg
    37321 tataattcat ttgattatcc attttttatt catcaaaatt actgaaaaaa gaaaggaaga
    37381 aataaatttg aagaaaacaa attcttcagg aaaaccgaaa cgcgacttca ctaaattatc
    37441 gacaccccat acgtatgtca ttatttttgg tgtagtcatc tttgcatgga tactgacttt
    37501 tgtcgttcca gcaggaaagt tcagcacgca agatattgaa tacaaagatg caaatggcga
    37561 aacaagtact cgtactgttt tacgtcaaga ttccttccgt tatgcttacg agctggataa
    37621 gtcgtatgtg tttgatcaat tagaagaact gcaagatcat ccagcagaac gtgaaaaact
    37681 ggatgttccg gaaaaaggat tggaaaaagt cattgctgac ggagaaaaaa atcttacgca
    37741 ggaaaaacta gatgaaatct ccttgacaga tgatgtgctt tacgatcagt acggcgaaaa
    37801 tatctatgat acttctaaaa aattgcataa aacagccaaa atatggggaa cagatgattt
    37861 tggcggcttt ggtttcttaa attttgtttt tgaaggacta gtatctggag ataagtatgg
    37921 atctgctgta gggatcgctg cattgatcct tgttgttgga ggtgcttttg gtattattat
    37981 gcgtaccgga gcgatcgacg caggtatcta tgcgtttatc agtaaaacta agggactgga
    38041 gcgtttagct ttaccgctat tattctttgc tttttcattc ggtggcgcta cattcgggat
    38101 ggcagaagag gtaattccat tctcaatggt gatggttcca tttgtcattg cgttaggata
    38161 tgactcgatc gtagcagtaa ccgtgactta tgtcgcatct caagtcggaa atgcgacctc
    38221 ttggatgagc ccgtttagcg tagcggtggc tcaagggatt gctggaatcc ccgtgttgtc
    38281 tggtgcgaca ttccgattga ttatgtgggt agttgttact gcattagccg ctggttatat
    38341 gatgatatat gcagaaaaaa tccgtaaaaa accagaaagt tcgttgactt acaaatcaga
    38401 tgattatttc cgttctcata tcaaaaagac atctgatgaa aataaaaaat tcatgcttgg
    38461 gcataaattg atcttattag agatgttagt tgtccttgtc tggatcgttt ggggcgtgac
    38521 tcaaaaaggc tattacattc cagaaatcgc ttctcaattc tttgtgatgg gattagttgc
    38581 tggaatcatt gctgttcttt tcaaattaga tggaatgaaa gtcaatgaca tcgcttcttc
    38641 tttccaatct ggtgcagctg atttagctgg tacagcaatc gtagtaggta tggccaaagg
    38701 gattcttctt gtcttgggag gatctgatgc atctgttcct tcagctttga atacgatttt
    38761 gcatgggatc gggacggcgt tgaccggtgt tccagctgtc attggtgctt gggcgatgta
    38821 catcttccaa agtttgttca acttggttgt tacatcaaat tcaggacaag cagctttgac
    38881 tatgccaatc atggctccac tggcagattt agtaggtgta tccagacaag tagcagttct
    38941 tgcttatcag cttggttcag gttttatgga cgcttttaca cccgtatcag ccagcttgat
    39001 tggtgtgcta ggtgttgcac ggatcgaatg ggcaaaatgg gcaagattcc aaatcaagat
    39061 gcaaggattc ctgtttgttt taggaactat tttcatcatg attgccattg caataggtct
    39121 gcagtagtac tggagacctg taaataaaaa agtaatccaa acagtagata aggactccaa
    39181 gaaccgtcat tttacggtaa aatcaaagga gtaaagatcc tatcgtttgg attatttttt
    39241 aagatcctat catcagttat act
//
LOCUS       DAKCAA010000023        37664 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000023 DAKCAA010000000
VERSION     DAKCAA010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.023"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..1083)
                     /locus_tag="OUE31_001274"
     CDS             complement(<1..1083)
                     /locus_tag="OUE31_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HCU0222293.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVFLLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIV"
     gene            complement(1237..1767)
                     /locus_tag="OUE31_001275"
     CDS             complement(1237..1767)
                     /locus_tag="OUE31_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCU0222294.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(1866..2216)
                     /locus_tag="OUE31_001276"
     CDS             complement(1866..2216)
                     /locus_tag="OUE31_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HCU0222295.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(2373..3902)
                     /gene="ahpF"
                     /locus_tag="OUE31_001277"
     CDS             complement(2373..3902)
                     /gene="ahpF"
                     /locus_tag="OUE31_001277"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HCU0222296.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(3912..4475)
                     /gene="ahpC"
                     /locus_tag="OUE31_001278"
     CDS             complement(3912..4475)
                     /gene="ahpC"
                     /locus_tag="OUE31_001278"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCU0222297.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(4619..5281)
                     /locus_tag="OUE31_001279"
     CDS             complement(4619..5281)
                     /locus_tag="OUE31_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCU0222298.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            5465..7111
                     /locus_tag="OUE31_001280"
     CDS             5465..7111
                     /locus_tag="OUE31_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HCU0222299.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            7102..8184
                     /gene="uxuA"
                     /locus_tag="OUE31_001281"
     CDS             7102..8184
                     /gene="uxuA"
                     /locus_tag="OUE31_001281"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCU0222300.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(8292..9845)
                     /locus_tag="OUE31_001282"
                     /pseudo
     CDS             complement(8292..9845)
                     /locus_tag="OUE31_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            9993..11134
                     /locus_tag="OUE31_001283"
                     /pseudo
     CDS             9993..11134
                     /locus_tag="OUE31_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(11260..12339)
                     /locus_tag="OUE31_001284"
     CDS             complement(11260..12339)
                     /locus_tag="OUE31_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCU0222301.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(12442..12882)
                     /locus_tag="OUE31_001285"
     CDS             complement(12442..12882)
                     /locus_tag="OUE31_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCU0222302.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(12939..13349)
                     /locus_tag="OUE31_001286"
     CDS             complement(12939..13349)
                     /locus_tag="OUE31_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCU0222303.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(13529..13963)
                     /locus_tag="OUE31_001287"
     CDS             complement(13529..13963)
                     /locus_tag="OUE31_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCU0222304.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(14063..14911)
                     /locus_tag="OUE31_001288"
     CDS             complement(14063..14911)
                     /locus_tag="OUE31_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCU0222305.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            15300..17066
                     /locus_tag="OUE31_001289"
     CDS             15300..17066
                     /locus_tag="OUE31_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HCU0222306.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            17168..18427
                     /locus_tag="OUE31_001290"
     CDS             17168..18427
                     /locus_tag="OUE31_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCU0222307.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            18574..19875
                     /locus_tag="OUE31_001291"
     CDS             18574..19875
                     /locus_tag="OUE31_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0222308.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            19878..20729
                     /locus_tag="OUE31_001292"
     CDS             19878..20729
                     /locus_tag="OUE31_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0222309.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            20742..21557
                     /locus_tag="OUE31_001293"
     CDS             20742..21557
                     /locus_tag="OUE31_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HCU0222310.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            21708..22874
                     /locus_tag="OUE31_001294"
     CDS             21708..22874
                     /locus_tag="OUE31_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCU0222311.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            23104..23751
                     /locus_tag="OUE31_001295"
     CDS             23104..23751
                     /locus_tag="OUE31_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCU0222312.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            23835..24779
                     /locus_tag="OUE31_001296"
     CDS             23835..24779
                     /locus_tag="OUE31_001296"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HCU0222313.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            24914..26365
                     /locus_tag="OUE31_001297"
     CDS             24914..26365
                     /locus_tag="OUE31_001297"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HCU0222314.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            26386..27222
                     /locus_tag="OUE31_001298"
     CDS             26386..27222
                     /locus_tag="OUE31_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCU0222315.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            27222..27881
                     /locus_tag="OUE31_001299"
     CDS             27222..27881
                     /locus_tag="OUE31_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCU0222316.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            28007..28696
                     /locus_tag="OUE31_001300"
     CDS             28007..28696
                     /locus_tag="OUE31_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222317.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            28702..29658
                     /locus_tag="OUE31_001301"
     CDS             28702..29658
                     /locus_tag="OUE31_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HCU0222318.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            29702..30214
                     /locus_tag="OUE31_001302"
     CDS             29702..30214
                     /locus_tag="OUE31_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0222319.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(30470..31018)
                     /locus_tag="OUE31_001303"
     CDS             complement(30470..31018)
                     /locus_tag="OUE31_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCU0222320.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(31107..32288)
                     /locus_tag="OUE31_001304"
     CDS             complement(31107..32288)
                     /locus_tag="OUE31_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HCU0222321.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(32524..34032)
                     /locus_tag="OUE31_001305"
     CDS             complement(32524..34032)
                     /locus_tag="OUE31_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HCU0222322.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            34191..34382
                     /locus_tag="OUE31_001306"
     CDS             34191..34382
                     /locus_tag="OUE31_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222323.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            34585..35502
                     /locus_tag="OUE31_001307"
     CDS             34585..35502
                     /locus_tag="OUE31_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HCU0222324.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            35495..36568
                     /locus_tag="OUE31_001308"
     CDS             35495..36568
                     /locus_tag="OUE31_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222325.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            36716..37234
                     /locus_tag="OUE31_001309"
     CDS             36716..37234
                     /locus_tag="OUE31_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222326.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            37215..37607
                     /locus_tag="OUE31_001310"
     CDS             37215..37607
                     /locus_tag="OUE31_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HCU0222327.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
BASE COUNT        12591 a         6848 c         7105 g        11120 t
ORIGIN      
        1 cacgataact aaaggtgaat agtactgtgg ttcgatcaat tgactttgct gtccaatttg
       61 taaaatgatc aaagccattt ctccacgcga aatcatacca gcaccgacca tcaatgaact
      121 atgttgagaa aaaccggcaa tctgagcacc aaaataacct ccaagcaatt tggtcaaaat
      181 cgctacaagc gtcaatatag aaataaagag tagttgttca ctaaagtcag aaaaatcaac
      241 ttctaatcct acactgacaa aaaatactgg tataaatact gcatatccta aagcctctac
      301 attgtggtat acttcttctt taacctttgt ctgactgaca gctatcccag caaaaaaagc
      361 accaatgaca gagctaagcc caacaagatc cgctacgtaa gacattccta aacaaataac
      421 tagcgatacg atgataatag aagaatttgc gtacactttt tctgcaaatg aaagtaggaa
      481 aggcgcaatc catttgacta ataagaaaat aaaaacaaaa taaattagct gttcaatcaa
      541 aacaagcggt aaagaagcat tgctagaagc ttcccccgtt agaaaagata ggctgaaact
      601 tagaactaaa acgactaaaa tgtcatctac cacagaagca cccaaaattg ttgatccttc
      661 ttttgtattc actacgttta gttcttttaa tacttctact gaaatactga cagaagttgc
      721 cgcaagaata atcccaaaga aaatcgcttc atttcccgaa acttggaatg ctttgcctgt
      781 caaccagcca aaaacaaccg ggaagatgat cccaagcaaa gcaacgaaca taccaggtcg
      841 gaaatatttt ttcaaaagag ataaatcact ttccagacca gctaaaaaca ttaataagaa
      901 cacaccaatc tccgaaaagt catggactag aatatcaggt ttgacccaat tcaatccagc
      961 ttggcctagc aaaacaccaa caagtaattg tccaatcact gctgggatac ctaatctccg
     1021 cgagatatgt gagccaatcg ttgttgaaat caatatcagg cataaaatac caataaattc
     1081 cattctcatc attcctttgt ataaaatata gcccgaactt agcataacat acattattga
     1141 aaaaatagga aaatatactc acaaaaaaac caacaatcca aaagattttt ttggattgtt
     1201 ggtttttata cggtctattt taataactaa aaatgattaa cgtatagtca tttttcttat
     1261 tctgatgaaa ttgataatct cctggatgcc catgaaaatc aaaataaagc cgaatatttg
     1321 gaatagaagc atcaaacttt tgaatggatt gaacaataag acgaatccgc caatcaacaa
     1381 cagaatacta ctataaacac tccaactttt agcttttgta ttcatgctga agaacaactg
     1441 gaacaagctg ttgatgataa cagctaatcc aagaagaatc ggcaggatag aaacgattgc
     1501 aggtgcaaaa gcatagacga tcagagctaa gatcaggaaa aaaagaccac tgaacagacc
     1561 gatactccaa gaacctgttt tccttttaaa acggtaagcc tcaaaaagat tcaacaaccc
     1621 aagcaaaaca agataggcgg tgatcagata accgataaaa tgaaaaacag cagaagggtt
     1681 tagcacaatc gcaatcccag aaataatata aacagcagct cttaataagg cgtatttttg
     1741 aatattttgt ttaatcgtct caaacatata agaaaacctc ctttgactta ttttaacgtg
     1801 aactagtcat tttaccaaat taaatgttac aaaatgagcg aaggagaaga atatctctgg
     1861 aaaaatcaac ttctgaggat cttttccatt tttttgcctt ttgctagctc atcgatcatt
     1921 ttatctaaat aacgaatttc tttcatcaag ttatcctcga tgtcttctac tcgtacacca
     1981 caaacaacac ctgtaatcaa ggaacgtgaa ggattgggga caggggcttc cgcaaaaaat
     2041 tgttcgaaag tcacttgttt ttgtagttga tattctagtt ctgtttggga ataacccgtc
     2101 agccaacaaa tgatttcatc tacttcctct tttatacgat cttttctctc cgcttttgct
     2161 acatacatag gataaacgct tgcaaaactt gtcgtaaaaa tacgattttg cgccataatc
     2221 agtcaccttt ctttttttca aattatttac tacttatagt atataagaaa aagagaagaa
     2281 aaagcgatta ttcaaaaaaa caaaaaggat tgtgacaaaa ttcttgtcac catccttttt
     2341 tccgctctct gactttttac aatcttcata gctcaagtgc gcatcagata atcgaatgct
     2401 cctaaagctg cagtagctcc tgaacccatt gaaacaatga tttgtttgta tggactatct
     2461 gtacaatcac cagctgcgaa aacgccgggg atattcgttg cgccattttt ctcggtcact
     2521 atttcatttc ttggattcat ttcgatcgtt ccatctagcc aatccgtatt agggagtaag
     2581 ccgactagaa tgaatactcc tgaaacagct agtgtatgca tctccatcgt acggcgatcg
     2641 atataggaga gagattctac ctgattcgta ccgctgattt ctttcgtcgc tgcatgtttg
     2701 ataacagtga cattcgcaag agagactagt ttatcctgta agatttgatc tgcttttaat
     2761 tctggtaaga attctagaac atatacatgt tttgctaacc cagccaaatc gattgctgct
     2821 tcaacaccag aattaccacc accgataaca gcaatctctt ttcctttaaa taaagggccg
     2881 tcacagtgtg ggcaataagc aattccttta tttttaaact ctttttcgcc tggtacattg
     2941 atagaacgcc agtgcgcacc tgtcgcgatg atggcggttt ttgctttaag tgatataccg
     3001 ttagctaagc caatattaat aaaatgttgc tctttattta aggaaacggc ctgttgattc
     3061 atcataatgt cgatagggta actacgcaca tgactttcta cttgctgcat caattttgga
     3121 ccttctgtgt aagaggtacc aatcatattt tcaatcccta gtgtttcaac gacttgtccg
     3181 ccgaaagaat cagcgacaag tcctgtacgg attcctttac gtgctgcata gatagctgca
     3241 ctactagctg ctggtccacc gccaatcact aatacatcat aaggttcttt ttcaaacaac
     3301 tcttcttcaa tcaaagggcc agtgattttt tcaacaattt gttcgatcgt catgcgtccg
     3361 ctactaaatt cttctccatt taaaaacaca gttggcactg ccatgatttt tttatcatcg
     3421 atttcttttt ggaacatccc accttcaatc atcgtatgag taatatttgg atttaataca
     3481 gctaatatat tcaatgcctg tacaacgtcg gggcaattat gacaagtcaa gctaacataa
     3541 ctgtcaaaat gcaatgtttg tgttattttt ttgattttaa gactcaaaga ttcactgatt
     3601 ttcggtgccc gtccactaat ttgtaacata gccagtaaaa aagaggaaaa ttcatgaccg
     3661 agggggatac cagcaaaaac gattccactt tctttgccaa ctggattgat agaaaaacta
     3721 ggtgtgcgca tcgaatctct tttttcccaa gagattttag gagacatttc tgctatttcc
     3781 ttcgtaaatt cagctagttt ttgactattt tcactattat ccaaactaac agaaaaaaca
     3841 ataggagatt caatcagtgc taaatattgt tcgagatttt gtttagtttc tttgtctaac
     3901 atatccacca cctaaatctt tccaacaaga tcaaaacttg gtttcaatgt ttcgccactt
     3961 tctttccatt ttgccggaca aacttcacct gggtgggtac gtacatattg agcagcgcga
     4021 atcttatcaa tcagtgcact agcgtcacga ccgattccat ctgcattgat ttccatagct
     4081 tgaacgattc cgtctggatc aataataaat gttcctcgct gagctaatcc ttgctcttca
     4141 tccaaaacat caaaaatacg agaaatctga tgagacggat caccgatcat cacgtattcg
     4201 attttaccga tagcatctga tgtatcatgc catgctttgt gagtaaagtg ggtatcggta
     4261 gagcaagaaa agacttcaac acctaaagat ttcaatgtac tgtattgttc ttgtaagtct
     4321 tctaattcag taggacaaac aaaagtaaaa tcagctggat agaagcaaag aatactccag
     4381 ttccccataa gatctttttc actgacttct aaaaattctc cttgatgata agcatgtgca
     4441 ttaaattctt cgattttttt cccaatcaat gacatagtaa aacctccaat aataattatt
     4501 tatttataat tattgtaatt tagttggagt tgcaaagtca atggatattt tgttatttaa
     4561 taaagattac tcaaaaacga aggttaatta taaaaataga agaggtcgca agaaaatgct
     4621 actgctggaa atactcggga taacgttgag taacagtttc ctgttctttc agcatcatgt
     4681 gtaagtgcaa tcccgtttga aatcgagctt cttctggttt tttatcaact aaagccttga
     4741 gtaaatcata atgttgttcc atgatcgttt cccatggaag cccctgaatg gtcactcgta
     4801 accagcggaa acgttctaaa tgggtattat ggtcatctaa ccagttccaa acttcttttc
     4861 ttcctgcaat ttcgaaacaa gcttcatgaa ataaattatc tgcacggaaa aaagcgcgtt
     4921 cgtcatttat tttgactgct ttttcttgtt cttctaaaat cgtttctagc actattcgtg
     4981 tttgtgtgtc caatttggaa caacattcaa tcatgatttg ctcttccaac tgttctcgga
     5041 caaagcgagc attttctgca gaaacaagat taattttgga aacatacgta ccactttgag
     5101 gtatcgtata cacgagttct tgctgacgta gttgaatcaa tgcttcgcga atgggagtcc
     5161 ggccgatagc aagatgttcc tccagtgcct tttcagatat tttccttcca ggttctaagt
     5221 cagcatagat aatttgttta cgaatcgctt gataagcttg tgattgcaag ctgcttttca
     5281 tctttattcc tccaaaatca tttctatgaa cgtagtataa cagaagaggt ctgaaaaaca
     5341 atctggtatg tcacattaac tagtaaattt gtataaatag taaaattttg gttgacatag
     5401 cgatttttat tgcataaaat tcacttgaat acaaaaacta atatgttagt ttaggagggg
     5461 aaaaatgatt gatttaaaca actggaggaa ctttatccct gaattatctc aaaaagaagt
     5521 agaaatacct cattttgacc gtgcatcatt aagagaaaat ggacaaaaaa atcctgtctg
     5581 gatccatttc ggtggcggaa atctttatcg aggatttcat gcagaaatcg ctcaacgttt
     5641 agcggatcta ggcgaattgt ccactggtgt cattgtttgt gaaacattcg atgaagaaat
     5701 aattgaaagg gcttaccaag attttgatga tttgattctt gaagtggtca tgccaagcag
     5761 tggagagttc gtcaaacgta tattagctgc gacagctgac agtctgtatt gtcatccaga
     5821 ttgttctgaa cactttgata agatgattcg acactttgaa aatcctagtt tacaattagt
     5881 tacttttgct attactgaaa aaggttatcg attgaaagat acaaataata aatatatagg
     5941 accgattgca gtcgatataa aaaatggtcc aaagaagcca tcacatacaa tgagtattct
     6001 tgctgtgcta ctttataaac gttttttatc tggagcttgg ccgattgcac ttgtctctac
     6061 agataatttt tcacaaaacg gtagtcaatt acgtacttct ttgctaacga tcgcaaaaga
     6121 atggcaaaag gaaggttatg tacaaaatac atttatccaa tacttatcga atgaagaaat
     6181 tgttgcgttt ccatggacga tgattgatcg tatcaccccg aatccttcct tgtcagttag
     6241 caaaatgttg gcaaaagagg gcttttcaaa tatgtcgatt ttccaaaccg caaaaggaaa
     6301 taatattgct ccatttgtca atacagagga catccattat ttaatcatgg aagatcattt
     6361 tcccaatgga cgtccgaaat tcgaaaaagc tggggtattc ttgactgatc gtgcaacggt
     6421 agataaagca gatacgatga aggtgacgac ttgccttaat cctttgcata cgtctttagc
     6481 tattatgggt tgtttactgg ggtataggag catagctgag gagatgaaag atccagattt
     6541 atcgctgcta gtttctgaaa tcgggtacaa tgaaggcctc ccagttgtgg agtctccagg
     6601 tatcattgat ccaaagatct ttctggaaga agtaattact gtgcgctttt ctaatccaaa
     6661 tattcctaat atgcctcagc gaatcgccac ggatacctct caaaaggtgg cgattcgtta
     6721 tggtgagacg attaaaaaat atatggaaat agaagttaaa gacccgcaga cacttgtatt
     6781 cataccattg actctcgctg cttggcttcg ataccttatt ggcattgatg atcaaggaaa
     6841 accattcatc ccgagtccag acccactatt gacagacctt cagcataagc tttccgatat
     6901 tcaactgggt acgcaagata catcacatat tcatgagaaa atggctccta ttttgtcaaa
     6961 taaagaaatt tttggtgtag atctttacca agcagagctt ggcagaaaaa tagaagaaat
     7021 gttcatcaag atggtagcag gaccaaatgc cgtacgaaaa acattacagg attacttaca
     7081 agaacatgga ggaaatttat catggaaatg acttttagat ggtacggatc acaggaagaa
     7141 aagattacct tagatgaaat cagacagatt cctgcggtca aagggattgt aggcacattg
     7201 atggatatac cagtaggaga ggtatggcct agggagagga tcaaagaact aaaagaagaa
     7261 attgagtctc gtgggttaac actaaaagta attgaaagcg tcaatgtgca tgatgccatt
     7321 aaaattggat taccttcccg tgagcagtat atcgaaaact ataagcagac aatccgaaac
     7381 ttggcagaat atggaataga agtcatctgc tataatttta tgcctgtatt tgactgggtg
     7441 aaatctgacc ttgactaccg cttagaagac ggctcatcca cgttagcttt tatatctgat
     7501 gatattccag atgatccaag agaaatcgtc gcgcgcatcg aacattccag caatgaattt
     7561 ggattgccgg gatgggaacc tgagcgctta gctcctatca aatccttgct tgaagcctat
     7621 gcatcagtag acgaagaaaa acttcgagaa aattttgcct attttctcca atcaatcatc
     7681 ccaacatgtg aagaggtagg ggtcaaaatg gctgtacatc cagatgatcc gccatactcg
     7741 atttttggat tagctcgaat cgtaaagaat cgagaagatt tagattggtt gtgtcgcata
     7801 gtagacagcc cttataacgg aatcactctt tgtacaggga gtattgcaga agatccagaa
     7861 aatgatgtat atgggatttt agcagaattt tgccaaagag atcgaatccc atttgcacat
     7921 gttcgaaata ttaaattttt agctaatcga gatttctatg aggcaccaca taaatccgaa
     7981 tacggttcat tagacatgta ccgcatacta aaaacaatgt atgacaacgg atttaacgga
     8041 tacatccgtc ctgatcatgg aagaatgatc tggaatgaga caggaagacc aggatacggc
     8101 ttatatgatc gagcattagg tgctgtttat ctaaatggat tatgggaagc aatcgaaaaa
     8161 ggaaacaaaa gtaaagataa ttagtgaaaa aaactgtaat tttattatgt aaataagaag
     8221 gatgttcaaa ttcttgatac ataaatccgg aggttgttaa taagcattcg gatttatgta
     8281 tcttatttgg tctaggaagt aacttgattt tcttttttcg attgatccat gagtgcttct
     8341 tcttttaatt caaagatata ttctgagatc ctcataatca cttttttcca gtcttctggt
     8401 gtgatgattc cttttaaaat atagattttt ttgatatgag aaggcaattg tttcaaaggg
     8461 cagtcgctga taacgatgtt gcagttctcc ataaaatcat tttgtatttt gatcgattca
     8521 tttgaaaaaa tttgttctat cttaacgatc agatctttac tgatataaaa atcacgcgta
     8581 tagttcacac caatcacaat tcgcggctgt tttttgtagc gatcatacaa atgtactagg
     8641 tcttcaacca tccattgcac attttccttt tctaaaataa ctggtaacaa gtgttgattt
     8701 tgttctctga aatccatata aaattgttca atggcggttt ggacttcttt caatacgcta
     8761 tgttcttgat aaagcatgaa agtaggaagg ggcgtatttg gttgattgaa gttaagaaat
     8821 ccattataaa gtttatttcg tgcgaatgcc aatgagtaaa gaatcttttc tttttcaggt
     8881 ataaacaaat caaatacagt acaaagggac tccaccattt ctcttgaata aagaacatga
     8941 ggaacgtttg ctttttttaa aagtttgtat tgctccaagc ttgtttcttc cgattcgatt
     9001 ttcgtgatag aaagtcgagc taaaatattc actaagatgc gttgttcgcg acaaattggc
     9061 agattaggtc gcaaaatatc tacagagaga tcaataaaaa agtcaatata ttcatactct
     9121 gtgaattctt tttgtacgtc tttcacagaa gttgcaggaa aattctcttt acatattttt
     9181 aatagaaaat ataatttatc tatcataccg ctatttagtc ggtcaagtac ttctttttta
     9241 aaaaaagtat tcatcataaa agccactact tgcggatctt catcataaaa ttctgtagca
     9301 gtacttgaaa agatgttcca ataaatatct aatgctgcat attgaatttg tacctctttt
     9361 ccagaaaaag actttctgcc attattagaa aaggagatag acaaaccgta ctatgctaaa
     9421 aatgcattaa tctttttcat tttcgtatac aaataagagg cactatagtt tgtttgctga
     9481 ctgaaactga taatcgaatt tgtctgacag ctgaacaaag aagtcaagat ctgataactg
     9541 actgattcgt tgcagtatct tccaaataga cgataatagc agtaagccgg atcaattcct
     9601 tcaaaattca actttaaaaa aggtttttgc ttatcaatat gcagttctgt tagattgaga
     9661 cgctcaaagt cttgttctaa ttctttgatg tatagtaaaa aatttgattc agacatatgg
     9721 aaatgatctg ctaaatattg tgtagtaata aagaaacgat gttcagatag gaaaagaaaa
     9781 atatctaatt ttgtattgct ttttttcttc aagataaacg ttttaatcgc ttcttgagtt
     9841 tgcatgaaag aggctccttt ttacttaaat tgttaaaact tgaaaatatt actgtttttt
     9901 tcataaattt agacaaaaaa acagtaaaca tataggtaga atctctacta tcttatttct
     9961 tgcatacaaa aaaatcaagg agtgagagag ttatgagata ttcaaccatc ttaatatcaa
    10021 catttgcagc cttaagctta tcgcttacta taaatcagac agtccacaca gaggagacag
    10081 aaacagccaa atggacagaa accaagtggg ccaacgtcaa tcgaattacc tttcaggatg
    10141 aattttcatc cttcaattca ggagtcgcaa aattaagaaa aggacaaaca gcgaccatca
    10201 aagcaaaaat tgactattcg ggagacttag cacctatact acaatcagct gttacatttg
    10261 agaatgttga tcccactttg tcgattggct atgacgagaa cactttgact atccaacaca
    10321 agcaagcgat atttaccttc accgttacat taaatcagga cttgttaaaa ccagcgcttt
    10381 ttactgtcaa ggtatcagat ggactaccga acgatcatca tttaacgccg tatagtcagc
    10441 ggcagacaat tgagcaagat tcagccatcg actcaggagg agatcttgtt gaagaaccaa
    10501 cagataaacc agaaaatgaa aataagccag aagtaccgcc tacagaaaat ccagacggag
    10561 aacagaaacc ggaaatagaa cctggagaag aacccgatac agaaactcaa ccagagccag
    10621 acaataaatc aaaacctgaa ataacccctg gagaaaaacc agatgtaact ccagaaccag
    10681 atacggattc tggaaaccaa acagtaccgg aaacaaatcc agacacagat aatgaaactg
    10741 aaaatccaga aaaaccagag gtagatccag aagaaaaacc agatgtgact ccagaaccag
    10801 atacggacgc aagagaccaa ggaataccag aaaaaataaa caaaaaaaca attcaagagg
    10861 atggaaaaaa agagagtaaa aaatcaaatc tagcaattct aaaaataaat gaagagcagc
    10921 tgaataaaaa atcacgaata tttgatagcg cccaatcagc tgaaacctta aaaagtagca
    10981 aggatacaac ctttgctgtc ctgaaacgaa aaataaacag ctaccaaaat ccggagagtc
    11041 acaaaacaaa gttatactgt ggagcggaat cattctatta agtatagcaa caatgctttc
    11101 tgcaaaaaga tttaaacaaa acagatctct ctaacatttg aataatgtct gtgaacgcat
    11161 ttttcaaata aaaagaaata tccagaaaat gaccccaaaa taccagattg aaatctgata
    11221 tttggggtcg ttcatacttt atctttcttc atatttattt taagggatat ctgtttcttt
    11281 tggaagatgg ttcgggatct ttttcacttt caatacatct aaaaagaagg taaagatcgg
    11341 aatgccgaca atcaagcccc aaacgccaaa gaaccgttcg ctaacaagta agaccacaaa
    11401 tgtataaaaa atcggcagtt ctgttttgct ggacatcaac ttcggattca gcacataaga
    11461 ctcaattaga tggacaatca aaatcgtaat caggatataa acaacatctc ggatgcctcc
    11521 ttgggaataa gctatgaaag atagaggaat acaagaaatg ataacacctg ctactgggat
    11581 cagacttaaa atgaaaatca tgatcgctaa actcagcagc tgatgaaagc caaatacagc
    11641 caaggcgatt gtagtgagca acgtatttaa aagagcgaca acaaattgag cttctaatac
    11701 caaaccaaat gtattgacaa acttatcggc aaaatagtaa atatcttgaa agaaccaaga
    11761 aaattcactt tttaaaaaca atcttgagaa tacaattgtt tttttctttt caatcataaa
    11821 aaagaaactt aagatgaatg acatagcaaa cgccactgcc atttttccta tatcctgtaa
    11881 atagccaagc gcaatcgaag cgccattttg aagctgttca aaaaaatcgt ttcgctcaat
    11941 ataagtatgg atatattgta aaacaggatc tgcatctttt ggctgatgct cgtaaaaatt
    12001 aataacggac tggatcatgt caaatgtttg atgaataagc atcgggatat actttgtgaa
    12061 tgccagatag ataaggtaaa cgatcagtgt ataaatcatg atagctaaaa cacctgtagg
    12121 gattcggaca aatcgctgaa tgatttgaac aagatgaatc atcaaataag taaagataaa
    12181 tgtgagcaaa atggttgtaa tcatacttct aactaagaaa agaacaaaaa cgacaaataa
    12241 taaaacagtg agacggcgta ttttttcatt cgccaaaaaa cgctgataaa cggtcaaatc
    12301 gacaacctcc aaataacaaa aaataaacac gttattcatt atatgatgga atatgaaaat
    12361 aagaaagagc aaaaagaaaa accgctaaat gacgttatct tatgagttgg ttttcctcat
    12421 aaaatcgttc atctagcagt ttcagccctt tttctggtct tgatgaaaat tatctagcat
    12481 ttttcgggtc agatgttgca gtgtatccaa ttcttcctgt tcaagtggaa gataagactt
    12541 gatcttttgt ggaatacctt ctgcttgttt ttgcaacgca gcaccttgag cagtcagcgt
    12601 aacatttacg attctttcat cacccgtttc acgctgacga ttaatataat ttttttctgc
    12661 taactttttt agtaagggag tcagcgtacc agaatccaga cacaaatcat ttcctagctc
    12721 tttcactgaa gtctttttct tttcccataa aactaacatc acaagatact gggtataggt
    12781 aagattcagc ggcttgagga ggggagtgta gtgtctaatg atttctttag aggcggcata
    12841 taaaggaaaa catacttgat taactaaata tagatcttcc atttttccac ctccgctgtt
    12901 ttactatagt gtatcatagc ggatttacac aaaaaagtct attcactaac tgctttcaga
    12961 gtaacttcta tatttccagc tgtagctttt gaatacggac acactttatg cgctgcctct
    13021 aataattctt gcgtttcttc cagagaaaga ccttcgatag atccttcaat ctctacacct
    13081 aagacaaagc tcgtttcact ttctgaataa agggaaactt gtgcactgac agtagaagcc
    13141 ccagagatat ttttttgctg tttgatcaat tctaatgcac tgttaaaaca tgcactgaaa
    13201 ccagctgcaa acaattgttc agggttggtt gcattttcga cgcgtttacc aggagctgca
    13261 atattcaatt cgaatgtacg atcgggatta tgcacttctc cagagcgtcc gcctgtgttg
    13321 atcattttcg tagaatacat ttttttcata aagttaccac ctttaattat attttataca
    13381 attgaatttt acacaatata attgtggaaa gcaaagaaat ggattggcat aagataaata
    13441 agagaaagca catgaaacag acgcgctttc tcgaatagca aacatataca aaaaatatca
    13501 gagacaaaaa ataatctcat cataaacatt acatatattt ctcaaaaagt tgttttcttt
    13561 cttcaaaaat tacttcacga tggacctgat gaagcatcca taaataacca aaaggatctc
    13621 tgaacattga gttagtcaca ccaaagtcca tcatttctgt catttcttga atctctacac
    13681 agccatttcg taatgcttta ttatgtgtgt cctcgatatc agagacgatg atattgaacc
    13741 agatcgtatt tggatgttca gcagtaggag cagtcaaacc aagagacgtg ttttcatcca
    13801 gcatatggaa tctcgtacca tacaaggtaa aaatgacttc attattgcct ctagggtaat
    13861 ctgttgcctc aatcagttgt atttcatcaa agattgtttg atacagttct agtgctttca
    13921 aactatcatt taatacaaaa tcgatttccg ttcctttatg cataaagatc tcctctcctt
    13981 ttcagtcgaa cagttactag attcttttat tataccagct aaagaaaacg cattcaaaaa
    14041 aatagcggat ttacttacca actcattcga ttggatgata agtaaatccg cgtcccatta
    14101 cttctgctac gctgctgaca atgacaaagg cacttggatc gatttcttct atcaatggtt
    14161 tcattcggga aaattcatga tcagtcacaa cgatcaataa aacctctttt gactttcgat
    14221 tatacccgcc ttttgcctct agcagggtaa ggccacgtcc aatctcagca cttaagcgaa
    14281 ggcggatgtc ttccaaataa tgttcactca tgaccataac agatttcttt cgattgatac
    14341 ctgtttcgat ataagtcatg acaattgaag tgattgcaat agataaaata gcataaagaa
    14401 actcttctat tccaaaaata aacagattaa gagaaacaac gaatgcgtct gtaaaaaata
    14461 agccaatcga agtattcaag tggaaatatt ttttaaaaat gaggggaggg atcgtcgtac
    14521 cgccgctaga agagttgttt ttatataaaa tcgcaactcc taaagcaaaa atcgcacttc
    14581 caaaaatgac agacaacaac cgatctgaag taatcattgt ttctggaact attgcaatga
    14641 ttaaaggaaa aaccaagctt ccgaaaagta ctttaaaaaa gggtttttta cctaaaaata
    14701 gaagagctag taccaacata acgatattca acactaaaat aactatagct cggtcaaagc
    14761 ctaaagcagc ttccagtaat attcctagac cgctgacacc tccagcagca atatgatgag
    14821 gccctaaaaa catattgata gcgactccta atatgaagag ggcaaaaata atcttaatgt
    14881 atgtccatat aaattgtctc gtttctttca tttattcact tccttaattc attaataata
    14941 ctcttatctt attataactt acttttcacc ttaagttaac tttaattaat aaaaaaatta
    15001 ggctagtcta aattattatg tttcattctt ctagaatata cttctacgcc aaaaactgtt
    15061 aaaaaacttt tactttagaa aattggagaa attgatcgct taagataaat tcaggacact
    15121 aaatagtaca ggaagtagac taaaactttt aaaagtttta agtctatcta tttggcaagt
    15181 ttaaaaaata aaaattcggt atcaaaaaac tgttaccgat aacatttttg aaagcgttgt
    15241 cttttgcttc tctatcactt atagtgatga cgtcatatta aaacacaagg aggaaatcaa
    15301 tggatacagc tgcaatttat catcgaccgg aaagtgaata tgcatttcta tatacgaata
    15361 caagatttcg tattcggctt cgtactagga aaaatgatat caaaaaagta tatgtgctat
    15421 gtggagatcc atataccata acaactgaaa aatggtatca aaaacaacga ccaatgaaaa
    15481 aatgtctaag taccaatgtt catgattatt gggaaattga agtgacgagc gaaacaagtc
    15541 gcttacagta tgcgttccat gttgttgggg aagataacac ggactgtttt tacggtgatc
    15601 aaggaatttt tccttatcga gaaaatgtga ttactgaacc aaatttttat tttcgaatac
    15661 cttattttca tcaaatcgat cgattcacta ttccagaatg ggtaaaagaa acagtatggt
    15721 atcaaatttt tcccgaaaga tttgcaaacg gggacaaagc aaatgacccc gaacacactt
    15781 taccttgggg aagtaaagat ccagaccgag aagacttttt cgggggagat ttgcaaggtg
    15841 tgatggatca tttggattac ttgacggacc ttggcatcaa tggcatctat ttttgtccca
    15901 tatttaaagc cacatccaat cataaatacg atacgattga ttattatgag gtggatcccg
    15961 cttttggcga taaaaaactt ttaaaaaact tgattgatga agcacataaa agagggatac
    16021 gtatcatgtt cgatgctgta ttcaatcata tgggtgtcca ttcaccacag tggcaagacg
    16081 ttctcaaaaa cggagaaaaa tcgatctata aagactggtt ccacatccgt tttttcccag
    16141 tagattctta tcagatgact gacttaccag aaactgctga aaatatccca tatgatactt
    16201 ttgcttttac tccattcatg ccgaaactaa atacagcaaa tccagaagtg caaaaatatt
    16261 tgctggatat cgcaacttat tggataaaag aattcgatat tgatggatgg cgtcttgatg
    16321 ttgctaatga agtcgatcat catttttgga aaaaattcag agaagcagtt acagaaatca
    16381 aaccagacat ctatatcctt ggagagattt ggcattcctc tcaagcttgg ctgcaagggg
    16441 atgaattcca tgcagtgatg aattatgcat ttacagattc gattaaagat tattttgcaa
    16501 aaaagaaaat cacagcttca caaatggtca gtggaatgaa tcatcagcaa atgctttaca
    16561 gagatcaggt gaacgaagga acattcaact tattagattc tcatgatact gccaggatct
    16621 tgaccctttg ccaaggtaac aaagaattga tgaagtctgt gatggccttt atgtttcttc
    16681 aaaaagggtc tccttgtatc tattacggga cagaaatagg gatgactggt gaagatgacc
    16741 cggattgccg caaatgtatg atatgggaga aggaggaaca agatctagag ctattcggtt
    16801 ttataaaaga acttgtttct ctaaggaaac agttgtctaa gattatttct gaaggttcta
    16861 ctcagtggct aatagtaaat gatcgtgaag ataagctcta tttcacacgg aaactagagg
    16921 gacagatcat ctatgtttac tttaatcagt caaaagaacc ttgggtagta gaacaggaaa
    16981 atgaggtgat tcttagtcaa aattgtcagt tgttagaaga cgggaaagca gagatacgac
    17041 aatacggatt tttgatcatg tgttgaaaac tgttaccggt aacaacaaga aagcgtttgc
    17101 aaatgaagat ttgtgcccat tataataagg gtgtaacagc acgttgaata caaaggagga
    17161 aatgaagatg aaaaaaagaa gtgtgaaaca gttgggttta gggttaatct ctttaggaat
    17221 cttaggcgga ttagcggctt gtggcaatgg taactcttca gcagaagggg aagccgatga
    17281 aggaaaaacg ttaacagttt ccgttgattc tggatataaa gattatataa acgaaataaa
    17341 aaacactttc gaaaaagaaa acgatgtgaa aatcaagcta gtagaaaagg acatgttcga
    17401 tcagttggaa tcattagcgt tagatgggcc tgctggaaag ggacctgacg ttatgatggc
    17461 agcatatgac cggatcggtg cgttaggaca gcaaggacat ctggcggaag taaaactggg
    17521 aaatgaagca gcttacgatg aaacagacaa agcccaagtg acttatgatg gaaaaatcta
    17581 cggagaacct gcagtaatcg agacccttgt tttgtactat aacaaagatt tagtcgatac
    17641 agcaccatca acgtttaaag atttggagaa tctatccaaa gacagtcgtt ttgcttttga
    17701 gtcagaagca ggaaaaaata caggattttt agctaaatgg actgactttt attattccta
    17761 tggtttaatt gcaggttacg gtggctatgt atttggtgat gatggcacaa atccttcaga
    17821 tatcggtttg aataatgcag gtgctgtaga aggaatctct tatgcaacag attggttcaa
    17881 aaatgtttgg ccaaagggaa tgcaagacat aaaaagtgca ggagacttcg ccagccagca
    17941 attcatgtcc aataaaactg cagcaatcat tgacggtcca tggcaagcgc aaacatacaa
    18001 agaaaacaat atcaattatg gtgtagccaa aattcctact ctaaataatg gacagcctta
    18061 tcaaccgttt ggcggaggaa aaggatgggt agtcagcaat tatgctaaaa acaaagacct
    18121 ctctcaaaaa tggcttgatt atgtaacgaa tcaggaaaat caagaaaaat tctttgaaat
    18181 ggtaaatgaa atccctgcaa accaacaagc tagggaaaca gcaaaggcta aaaacgatga
    18241 attaacaaca gctgtgattg aacaatatga aacagctcaa gcgatgccaa acatcccaga
    18301 aatgggcgaa gtttggacag gtgcagaaaa cttgatgttc gatgcagcat caggttcaaa
    18361 aacaccaaaa gaatccgcag atgaagcagt aaaaacaatc agtgaagcca tagaacaaaa
    18421 atactgatta aaatgataac cgtccatttt tataaaaaat ggaacaggtg cttcagataa
    18481 aagtggcaag agcgagatgg aaaattatct tgctcttgtt gccattatct taaaagcagt
    18541 ttgcggttta gcaagtttag agggggcatt cagatgcagc aagataaaac aagcaatatc
    18601 aacgaaaaaa aaatcacgct ttgttcactt attccaggga tggggcagtt tgtaaatggc
    18661 caagctttta aaggtatcgt ttttttcgcc atattcgtcc tattcattgg tcagatgctt
    18721 ctgggcggat ttcatgcatt ggtaggattg gttactttgg gaagtatacc aatggaagat
    18781 cattcattat ttattttgat tgaaggcact ttgcaattca tcattacaat cattttcttg
    18841 attttttacg gtttgaatct tttagacgct tatcgagtag cgaagatgcg tcaagagggc
    18901 aaaaaaatca atcggacgat gaaggaagtc atacataata taggtgatga aggttttcct
    18961 tatctattga cacttcccgc ttatcttctc atgattttta cgatcatttt cccagtccta
    19021 gttacattgt tcactgcatt tactaattat gacttcaatc atattccacc agccagttta
    19081 attgattggg taggggctaa aaactttttt agtatcttct ttttaagctc atatcgtaat
    19141 actttttttg cagtcttttc gtggaccgtg atttggactt tatgtgcaac aactttgcaa
    19201 atcacccttg gtattctcac agcggttgtt gctcaccaga aatttattaa attcaaacgt
    19261 attttcggta tcattttctt attaccatgg gcggtcccag cttttattac tatcatgagt
    19321 ttttcgaata tattcaacga tagcgtaggt gccatcaata ctcaagtgat tcctttcata
    19381 aaccagcttc cttttgtaga tatcagtgca atctcttgga aaacggaccc gaactggacg
    19441 aaagtagcaa ttatcttagt gcagggctgg ttaggatttc cctatatcta tgtgatggtt
    19501 acaggaatct tacaatcgat ttcagaagac ttatatgaag cagcaaaaat cgacggagca
    19561 aatgcatggc agcgcttttc aaacatcacg cttcctgctg tcttcctagt ggcagcgcca
    19621 acatttatta cacagtatac ggggaatttc aataatttct ccatgatcta tctgtttaac
    19681 aatggcggtc ccggaagcgt aggcggagga gctggttcta ctgatattct tatttcctgg
    19741 atctataaac ttacgactgg aacttctccg cagtattcta tggcttcagc aatcacgttg
    19801 attatctccg tcatcgttat ctgtgtgtca ttgctggtat ttaaaaagac aaatgcgttc
    19861 aatatggggg attaacaatg aaaaaatttc attcgagtgc tcgattccaa aaacgacttt
    19921 ctcacttttt tacttacttt tttcttttaa tactgtcagt cattatcatc tatccgcttt
    19981 tgatcacagc aagtactgcc ttcaagtcag gaaatattgc agcttttagt ttagatcttt
    20041 caagtgactg gactttagga aactttactc ggctattcag tgaaacactt tacgggactt
    20101 ggtataaaaa tacattgatc atttctgtcc taacaatgat cgtacaagtg actgtagtaa
    20161 ctttggcggg ctatacttat agtcgctatc gttttatcgg ccgcaaatca agtttgatgt
    20221 tctttttagt gattcagatg gtaccgacta tggcagcatt gactgccttt tatgtcatgg
    20281 ctttcttatt agaagcgctc gataagtact ggttcttgac aatgatctat ataggcggtg
    20341 gaattccaat gaatacttgg ctgatgaaag gatactttga cactgtacca atagatttag
    20401 atgaatctgc taaacttgat ggggcagggc atttcaggat ttttttccag attgtattac
    20461 cgcttgtcaa accgatgctc gccgttcaag cattatgggc ttttatggga ccttttgggg
    20521 atttcatgtt agctaagttc ctgcttcgaa cacctgaaaa tcagactgtt gctgtcggct
    20581 tacaaacatt tatttctgat gtgacaaacc aaagagtctc tctttttgct gctggggcaa
    20641 ttttgattgc actaccgatt tgtctattat tcttcttttt acaaaagaac tttgttaccg
    20701 gcctgacatc tggcggaaca aaaggatagg agcagagtat catgcaaaca tttccgttaa
    20761 actatttttc cgcattacgt acgccaactc aagtgtttgc gggacgcaaa ctattatcat
    20821 ggcctaaatt tttcttgata tttgtatttt tagtttcctt gatggtcatg cctgtgactc
    20881 ttttttatgc caatcagatc caagcgattc cattagaaca atttctatcc gttcattcgc
    20941 tgatcgatga acaaggaacc caaaaatttt ctgaacttga attatctgaa actgggttac
    21001 aagcatcgca acaaacgata gctgtgaccc ctgaaatttt ggtaggtgtg tctttatctg
    21061 agaaacaaca atccgatcat ggaactttta ttgattttga gaaggaacaa tgggtgatcc
    21121 aacaaaagga taaatctggt atacgccgct atacgatgaa ttatagccca tctttccaac
    21181 cagattctgt acgtacgccc gaagatttcc aacgattttt agaaagagaa ttttatgcca
    21241 gtaatcgtcc aacaatcatt ttatcttata gtttaagtct tggtcttgtc ctatttgtca
    21301 tgacgagtct cattttattc ggggcttcct ttttcttgtg gatgacaaga aaaagccaac
    21361 tttcatccat tcatacattc aaagagagtg caaatttgat gctgaatgtt atgggaatag
    21421 gttccatggc agcagcagtt gtagggttta tccactttga ctttatcttg atgctaagtg
    21481 tccaaacaac gataactgtc ttgctgcttt tatgggtttt tgtcaaaaca agattcaaag
    21541 ataagcgtgt cgaatgacaa gtttaagcga tttatgcgac aatgaatgtg aaaaaaatga
    21601 aaaataaagt agtttttgaa aaatttctga aaaaattaaa cttcttagtt gattcttttc
    21661 ttttttagta ttaacgtaat agggtagttt ttttaaggag gaaaatcatg ttagagaaaa
    21721 ctttatacaa tcaattattt tcacgttctt tctcgctccc tgtcgaagta aattattggg
    21781 acggtacaac gaaacaatac ggagatacgg acactcctcc ccaaatcaaa atcaatatcc
    21841 atgaagaaat cccaatgaaa gagattacaa gtaacgcatc tttggcacta ggagaagcct
    21901 atatggatca tcgaatcgag atcgagggaa gtatccaagc attgatcaac gatgcttatc
    21961 agcaagcaaa cagcttttta cgaggaaaag attatctaaa atggctgcca aagaaagaaa
    22021 aacatacgaa acaaaaaaac aaagaagata tccatgcgca ttatgactta ggtaacgact
    22081 tttataaact ttggctagat ccaactttga cttattcttg tgcttatttc aatacacctg
    22141 aagatacgtt ggaacaagca caaatcaata aagtccatca tatcttagac aaactcttta
    22201 tcaaagaagg cgaaacgttg cttgatatcg gttgtggctg gggaacattg atgttcactg
    22261 ctaccaaaga gtataatgtc aaggcaactg ggatcacact aagtgaagaa caatacgatt
    22321 tgattaccaa aagaataaaa gaagaacatt tagaagataa atgccgtgta ttattaatgg
    22381 attaccgcga actaaaaggc gaaacgtttg atcatatcac aagtgtaggt atgttcgaac
    22441 atgtaggttc tgaaaatctt gaaggttatt tcaaagtggt aaaagattta ttgaaaccaa
    22501 aaggaacagc tttgatccat ggaatcagcc gacaacaagg cggtgcgaca aatgcttgga
    22561 tcaataaata tattttccct ggcggttatg tccctggtgt tactgaatta gttgataata
    22621 ttacaaaaaa cgatttgcaa ctgattgatt tggaaagctt acgtcgtgac taccaattga
    22681 cattagaaca ttggacaaag aattttcatc aagtccaaga tcaagtcacg aaagaaatgg
    22741 gtgattcctt ctatcgaatg tgggatctat atttacaagc ttgtgcagct tcatttgaat
    22801 caagtaatat cgatgtgatt caatatttgc ttgttcaacc tggaaacaat gacatcccaa
    22861 tgcatcgtgc ataattgagg caaaagtact gtttaaagac tatttaaaaa gaagctaagt
    22921 tttatgatgc tccagaagtg aacttttttg tctaacttct aggattgtct ctaaagctta
    22981 gtttcttttt ctttatattt tcataataaa agtttggttc tttaattttt aaacatgaca
    23041 gaaaattttt tcttcgttat acttgtaata gaatactatt ttataacaaa ggggatcgaa
    23101 tcaatgaaaa aaactgttat ttatactagt ttatttgcag ctttgttttt agctgcttgt
    23161 caatcaaata ccaatcaagg cacatctggg aatacgtctt ccagtagcga acagcgctct
    23221 tcacaggtat cggactcctc aacaaaagca agcacatctt cgtctagcca gacaaaaagt
    23281 tctagtgaag caagtactca gtcagatatc aaagtgtctg cagctcgtgc gatcgaattg
    23341 ttccaagata aatacccaga tactgcaatt actagtttgg aattagatag tgattgggga
    23401 tcttacttct acaagataga aggtgtcgat gatcaaaaag aatacgaagc aagaattgat
    23461 gctcaaaatg aaaaaatgga gacagagaat ccagaaactc tagatcgaga tgaacaaaat
    23521 ggtcaaaaga aaaaagaaga tggtctggat gttgataaat tgatcacgat tgaggaagca
    23581 gcaaaaatcg ccgtcgacaa agtaggaagc ggtacggcaa cagattggga tttggataaa
    23641 gatttaggta ctacttattg ggaagtcaaa gtaaaagacg gcaatcaaag tacatcagtc
    23701 aagatcaata gccaaacagg cgaagtactg tcaactgaac aagatgatta agaatttctt
    23761 cggaaaacaa gagttgattt ttcttttagt catgatacac tagacaaaat aacttgtttg
    23821 aaggagcgat ttacttgagt ttagaaacga cctttgccaa tcatatcttt gccaatcctt
    23881 tgatgaatgc atctggtgtc cactgcatga ctacccagga attagatgaa ctggctcatt
    23941 cagaagcagg agcatttatc actaagagct gtacgatcaa tgaacgaaaa ggaaatcccg
    24001 aaccacgcta ttttgatgtt cctttaggga gtatcaattc tatgggactt ccaaacttag
    24061 gtttttctta ttatctagag tatgctcttg cgtatgaaaa agtgcaggaa aaccaaaatc
    24121 aaccgttatt tttttccatt gccgggatga gtgtccagga aaacttggaa atgcttgaga
    24181 aaatagaaaa aagtgggttt aatgggatca ctgaattaaa tttatcttgt cccaatgtgc
    24241 ctggaaaacc acaactagct tacgattttg aggccactta tgaaacactg aaagaagtat
    24301 tcagcatctt ttctaagccg ctaggaatca aattgcctcc ttattttgat tttgctcatt
    24361 ttgatcagat ggctgatatc ttgaatcagt ttccattgac ctatgtcaat gctatcaaca
    24421 gtgtgggcaa tggtttgtat atcgatacag aacaagaagc agtagtcatc aaaccaaaag
    24481 aagggttcgg cggcattggc ggagagtata tcaagccgac tgctttggcg aatgttcgcg
    24541 ctttttatac acgtttgaaa ccagaaatcc aaatcattgg tacaggtggg attcggacag
    24601 gacaagatgc atttgaacat ctgctatgtg gcgcaagcat gttacagatt ggtaccgagc
    24661 ttcataaaga agggccggaa attttttcta gaatcataaa agaattaacg cagattatgt
    24721 cagaaaaagg atatacgtca attgacgaat ttaaaggcaa attacgcacc atttcatagc
    24781 aaagagacga aggtcatgat tgatcttcgt ctttttttat aaaaaacact cgtctgttca
    24841 ttcctgtgca agcgtactca ttgtatgtta gacgaacttg tgggaaaata acagaggcaa
    24901 aaaggaggat aatatgaatg atgcaacaga attagcaaaa gagcttaaag aaaaagaatt
    24961 tagttttcaa gaactagtta cggatataca gaaaaaaata aagaagcaaa atcatgaatt
    25021 gaatgcgttt gtcgcgcttg aaccattcga gagtaattcc cacgagctat tgattcccca
    25081 gtcagaaaaa gggccattgg ctggtatccc atttccttta aaaatgctcg gtcaagaaaa
    25141 aaagggatgg ctagctactt caggatctcg tttatttgaa acacaccgag cttctcatac
    25201 atctaattat gtgcggcaag cagaagcgat aggtctagtt ccttttggac aaaccaatgc
    25261 gccagagttt ggtttcaaaa atattacaga cccagtcatc tatggcccag caagaaaccc
    25321 ttggaacctt gaatgtacac cgggcggatc aagtggagga gctgctgctg cagtttcatc
    25381 aggaatcgtt cctttagctg gtgctagtga tggcggtggt tctattagaa tacccgcttc
    25441 gttttgcgga ttgattgggc tgaaaccttc gcgagggacg atgccagttg gtccatatgc
    25501 ttggagagga tggcaaggag ctgctattga tttcggcttg acagtttcta tgagagacac
    25561 ggaggcttta ttttatggga tgagaagtat ccattccggt gcgccatatc aagtatcgcc
    25621 agttgagtgg caaacacatc caagaaaaaa acggttgaag atagcttttt gtgttgattc
    25681 accgatccac tcacagatta gtgaagaggc agtacttgct gtaaaaaaag ctgtagattt
    25741 ccttggaaaa gaagggcatg atttgacaga gattccttac ccactagatg gtcgtaaact
    25801 gatcacgtct tattatcaga tgaatggcgc agaaacagca gcaatgatcc gctcgattga
    25861 aacaggcatc cagcgagctg tcagaaaaga agaacttgaa cccatttctt ggactttgtt
    25921 ccaatatggt cagaagctct ctgccgctac ttacatcgat tctctgcatg tatgggatga
    25981 agcagcaatt gtcatggaaa acctacatca agaatacgat ctattccttt caccaacgac
    26041 tgcatttacc gcccctaaaa tcagcgaaga tttgcaaagt gatgcgataa gagcacagat
    26101 ggaacacatc agtgattgtt ctgaagtaga aggtttagac gttgtttctt ccatgtttga
    26161 ggagagcttg aagatcacac cttatacaca gttggctaat ctgactggac aaccagcaat
    26221 cagcttgcct actcatttga caaaagaaaa catgcctcta ggaatccaat ttatggctgc
    26281 cagaggaaga gaagatttgc tatttcaaat cggctatcta tttgaagcaa atcatcagtt
    26341 ccatttacca aatccatgga aatagcagaa acaaggagaa gaagaatgaa gaaaaaaaga
    26401 ttgtttgctc taataactag tgcctttttt attttaagcg cttgcggtac agctgccgct
    26461 aatcaggaag ataacagctg gagtaatgta gaaaaaaaga aagaattagt agtagcgact
    26521 tctggcacac tgtttcccgc atcttattat aatgatcaaa atgaattagt tggttatgat
    26581 gtagatttgg caaaagaggt ggctaaacgg ttaaatgtca aaatctcctt taaagaatac
    26641 aacgtggatg gacaaatcac ttctgtttca aaaagagaat cagattttgc tgcgaacgat
    26701 tttggtatca caaaagaaag agaaaaaaaa ttctcccttt cagagacttt caaatattca
    26761 tttgacagta tgatcgtacg aaaaaaagat gattcaggaa tccactcact tgaagatctt
    26821 aaagggaaaa aagcagctgg cgaacccaat actagctata tgcgtttagc ggaaaaacac
    26881 ggagctaaat tagtcacata tgacaatgcc acgaatgatc agtatttaag cgatgtagca
    26941 aatggtcgaa cagatgttat tctaaatgat tattatctgc agaaaatggc cgtatctgct
    27001 ttaccagata tccctgtaaa aatactggag aacgtttatt tcaatgaaaa cgaaagtggt
    27061 tttttattga aagaaggaaa tgatgctctg aaaaagaaaa tcgatggcgt attaaaagag
    27121 atgaaagaag atgggacgac aaagaaaata tctgaaaaat attttcaaac tgatgtttca
    27181 gtcaaaccga aagaaacgat ggctgagtcg gtgagtgagt gatgtacttt cctctaattg
    27241 atttttccct catgtggact tcacttcctt tcgtactgca aggcttggta tacacattag
    27301 ggattggctt cgtgtcgttt cttttaggaa atctggtagg gttgcttttg acagttttag
    27361 gtcttttgga ttggctgcct ctgaatgtat ttattcgttt ttatttatcg ttctttagag
    27421 gcattcccgc actagtcctg ctgtttctgt tatattttgg gttaccttat caattaagtg
    27481 ccttaacggc ttcagtcatc tgctttacga ttaccagcag tgcatttatt ggtgaaatct
    27541 atcgaggatc actagcaggc gtttcttcag gtcagtggga cgctggttta gcttctggtt
    27601 tttctttctt tggggtattg aaatatatcg ttttgccgca agcttttcga atctcagtac
    27661 cggcactcag taacgtagct atggatctag tgaaaggtac ttcgttagca gcaacaatca
    27721 cagtgccaga aatatttcaa aaagcaaaga tcataggcgg tcggacattc gattattttt
    27781 ctctctatat tttagttgca ctgatttatt gggtcatttg tatcgggatc gaaaaagtgc
    27841 aacagtattt agaaaaacgt tctatgcatc agtcaatctg aaaaatagaa atggtgctag
    27901 cgtggctggc accatttcta ttttttgttt cttgtatatt ctgcctagta ttttaaaacc
    27961 atttcatgta aaatgtaaat cgaaaatatg ttcggaggta gaaaacatga agaccccgct
    28021 aaccatcgaa atagaatcct cgttatacca atattgcatc gagcaaggcg gcttggttgt
    28081 agaagaagtc acgatgcctg atgaccaagg aattgtagat acgcttagct gcttgacaaa
    28141 atttgatgga agccgagaat ggcgatgcta tgagctgaaa gtgacaaaag cagattttcg
    28201 ctctacagcc aaactgtcat ttgttggaca ttataattat tttgttttac caagtaaact
    28261 atatgaagaa gtaaaaactg aaatccctac aggaataggt gttttagtgt atcgtccgta
    28321 cacggttgaa gaggagatgc ctgcctctgg tacatttctg attgcgaaaa aagcagcaaa
    28381 gaaagagctt gctgtaccgg aagaagcttt gacaaaccgc ttcatggctt ctttattcag
    28441 ggaagtaaga aaagcaaagc aaatggagcg aggcgtaaaa tattttccaa cagatcaatt
    28501 gtacaaagaa ttgaaaagac gttcagaaaa tcaagatcca ttttctaacg aacgatatta
    28561 tgaacggttt ttagaggaaa tagctagtca ggcaatcaat gagttgcaag aagaagttat
    28621 cgcgcttcag catgattatg aatatttgag gcaacaacag cagatccgtc ggttgcctac
    28681 agagccattg gagtgaaaaa tatgtactat ccttatttaa gaggaaaaca atttgaccta
    28741 ttagcattaa aagaagcact gtcgcgagga ttgctctcca ataaaatcca accagtgatc
    28801 gaaccagtac gtgattccgc tacgcttaaa aatgtgatcg aattatttca aaaaaagcac
    28861 catcgaatcg ctgtgatcca aaatccccaa gtaggacaat tcaaattatt cgatcagcat
    28921 gtgcacagtt ggacagtcaa agaaaatagc tctgtcgtcc ctgcacagat cttaacgcca
    28981 gaaaatctca gtgaagtact ggattcacct ccagcgtttc ttgttttcga tggacagcac
    29041 tacccaaaag atacagaggt gtggaaacag ttggcaggag ttgattcgaa atttttgata
    29101 ccagatacta gtcgctttcg catctggctg cccgaaaaca aaattgtgat ccgtgactct
    29161 tttcaaacga gaaagcatgt tgaaagttat gcagataaaa cagatgactt ttttagtgat
    29221 gactatcttt ttttccacgc agacggatat attggatttt ctgatttcac gatcgaaggt
    29281 agccgttatt tcgataaagg gttccctagc cgagcgcttg ctatccatct aacgtatatt
    29341 gatgcttacg gcaatatacg cgtgaaacat tttgtctctg acagtaacga ctctgctaaa
    29401 gaccaagcat tgaagtttct tgaagcagga gataaaatga aaaaatggat catgcgtcac
    29461 catcatcaac tcttgattac ttcaggaatg attgaattat tggctcttta ccagcaacaa
    29521 aaattccctg gactgggagt gttgaaaaag tggtcactta tgcatcattt ggaacttatt
    29581 agtcacctgc tagatcatcc aaaagattgg cttaaatatt attcaaaagt tcaggaacta
    29641 tatgaagtga tccaatgatt agataatgta aatgaaaaag gaatagaaaa gaggaaactg
    29701 gatgtatatt cggcaaacaa ggaaagaaga agtagaagaa gtggtagaaa tcattaatgc
    29761 cgcagcggat ttcattgctt cgcaaggctc tcctcaatgg caaaacgggc agaaaccaac
    29821 aaaagaaacg attttgaacg atattgaaag aaaagaaagc tatgtattaa tagtggaaga
    29881 tcaaattgct ggaacagctg cattagtctc aagcgtggat cccgtttaca caaaaataga
    29941 tggtagttgg aaagaatcaa ctggtcctta tttatcgatt catcgtgtcg ctttagcaga
    30001 aagtactcga ggaaaaaaac tagcaaaacc gttcttagaa catttgttga cgattgcagc
    30061 cagcaaaaat atccaagata tccgtatcga tacttatcca gctaatgaac cgatggaaaa
    30121 gaccatctat tctgctggat tcacttatca agggatgatt gaatttcctt ttgaacacgg
    30181 cgaaagaaaa gcatatcaaa taatcatcaa ttgactataa aatcatctga gcaaagataa
    30241 agacattaac actactgaaa aaaacaatca tatgatagcc aagaggttgt aacagaagtg
    30301 gccagcttca aaaaacaaga aagaatttcc gaaaatgctt ctcaaatttt tgtggaattt
    30361 tagcgtattt tacgaaatag ctgctttctg aaactccctt catcgagagg tcgtgacata
    30421 gcttttgtca cgacctctcg gcttatccta cgagtattat tcgatacatt tatatcaata
    30481 atcctttttt tattttatct gcagcttctt ggaacgctcc atcgtttgac acgactaaaa
    30541 gtgaggggat agctttcaaa cgtttcaact gtgctaaatc ttctacataa accgccagtc
    30601 tggctgaaat ctgttcagat gaatctccac gttttttcag gcgcgattgc aatgtttctt
    30661 tagagatcgt aataaagata ggacggacta ccgtcccgaa atactcatat aaatgccaaa
    30721 aaccatttgc tgtcaaaacg gcgtaacaat ttcctactgt cagtttcttt ttaatttctg
    30781 ctttactgga accatattta tgttgagcat attggtccca ctctgcaaac tcatttccct
    30841 tgatcatctg attgaatgta ttgtcagaaa caaaataata atcctcttga tctttttccc
    30901 caggtcttgg tgatcgattc gtgtaagtaa tgatcttttg ttccggctga aaaatagctt
    30961 ctgcgagtga agtttttcca gaaccagaag gaccgataaa tacatagcaa taattcattg
    31021 tcatttctcc tttgatgatt gaacaagtga aaaagctttg gaaaatattt ccaaagcttt
    31081 taaaagtaac tttgcttttt tgtatattat accagcaagc cagtcacaat agcacttaaa
    31141 aagctgacta aagtcgctgt tagcaaaatt ttcaatccgt gttttgcgac aagatttcct
    31201 ttttcttcat ttaatccctt catcgcacca gaaatgatcc cgatagaaga gaagttggca
    31261 aatgaaacga ggaagacaga tataattgct gttgtacgct cagtaaaatg gaaattacca
    31321 tttgctaatt ctgtcatagc aacaaattca tttgtaacca gtttagtcgc catgatacta
    31381 ccggcatcca ctgcttcttt ccatgggatt ccgctgatga aggcaagagg ggcaaagatg
    31441 taacctagga tctcttggaa agtgatgccg aatatcccgt ggaagatagc attgatcatg
    31501 gcaatcaaag caacaaaacc gataagcata gcagcaaccg tgatcgccac atggaaacca
    31561 tcaagaatgt attctcccaa catttggaaa aatgtctgtt ctttgttttc ttcaatgatc
    31621 agctcatctt ctttttcttc taatacatag ggatttacaa ttgaagccag aatataaccg
    31681 ccaaataagt tcaaaacaag ggcagtgatc acatatttag aatcgatcag tgccatataa
    31741 gatccgacga tcgacataga aactgtagac atagccgata cactcatggt gaacaaacgt
    31801 ttctcagata ggaagggtaa ttcctttttt atggaaataa aaacttccga ttgtcctaaa
    31861 atagcagaag ctactccatt ataagattcc aatttgccca tcccgttgat tttacttaat
    31921 cctagaccaa cagctttcat aaataatgga agaatcttga tatagcgtag aataccgata
    31981 atagcagaaa taaatacaat tggcatcaat acggaaagaa agaaaggtgc acttccttta
    32041 tttgctacac cggcaaaaac aaagtcaaca ccttgcccag caaaagcaag aagatgatca
    32101 aacatttttg ccaatacaga aacaaccgct gtaccaaaag ttgtacgtaa taatacgaaa
    32161 ccaagaacaa gctgtaaaac gaacatcaca attagtggtt tcaatttgat tgcttttttg
    32221 ttactgctga tcaaaaaagc aagccctaat gtgacaaata aaccaataat acctaataaa
    32281 taactcaaat aatcactcct attccaaatt ccgttttatt ttacctgttt tgcaaataaa
    32341 atactaatct ttagtgaaat tttcattact tttttagagt gaaacgcatt cattttccat
    32401 tagaaaataa agcgaacaaa ataaaaggtt taaaaagtgt aacgtcttag taaagtctat
    32461 aaaaaaacga aactatcgat taagctaata gtttcgtttt caacatttat aagtaaactt
    32521 tttctattgg taatatagat tttcggaagg gtagacaggt gcgcaggtaa tatcgattcc
    32581 tagttttttc aatgtttgtt catcattttt attgaccatc acagtagagt gggcttgtgc
    32641 tccctcaagt tcagctagtt tatcataagc aacttgagcg attggattcg ttactgcact
    32701 gattgataaa gcgatcaaga cttcattgat gcttagtgca tccaaagagg aatgaagtgt
    32761 ctttgatttc aatccttgta ttgtttcaag aactaatggt gacaataaag gaatgtcatc
    32821 tgcgatatgg gctaaatgtt ttactgcatt taagataact gccgctgacg catccatcaa
    32881 tgaacttgta cgcccggtaa tgatgacttc atctggtaat tcgattgcaa tcacagcaga
    32941 aggatctttt gtaggacttt gcgcttgaat cttatctgca tagtcatggg cagggactac
    33001 cacgtttcgg tcttcaggac gtaaaccgac ttcttccata atcagtttga ttcgattaac
    33061 tgcttcttcg tcgatcaatc cttttttgaa gtcgcattct gtttggaaat aacgacggat
    33121 gatttcttgt ttagaggctt cttggacaac ggtatcatcc acgatcccaa atcctacacg
    33181 attcacaccc atgtcagtag gagattgata aacagattct ttaccagtaa ttttttcaat
    33241 aatacgtttg attacaggaa atgtctcaac atcccgatta tagttcacag ctactttatt
    33301 gtaggcatca aagtggaagg aatcgatcat attgacatct tttagatcga ctgtggctgc
    33361 ttcataagca atgttcagcg gatgtttcaa cggaacattc catactggga aagtttcgaa
    33421 cttggagtaa ccagctgcat gtcctttttg gctttcatga tacagttggt tcaaggaagt
    33481 agcgagcttt ccacttcctg ggccaggagc tgtcactaca acgattggtt tagttgtttc
    33541 aatatactca ttttttccaa aaccatcttc tgagacgatt ttttctacgt tgactggata
    33601 gtcttcgatt tctgagtgtt tatagacctt gatgtttcgt ctttctagtt tattgataaa
    33661 gactttcgtg gcaggctgtc cactatagcg agtgataacg acactgttga ttaataagcc
    33721 ataaccacgt aattcatcga ttaaccgcaa gatatccata tcataagtaa tcccataatc
    33781 accacggatc ttattacgtt caatatctcc agcatagacg caaatcagta tttcagcttg
    33841 atctttcaat ttttgcagca atttgatttt cgcatcttct tcaaatcctg gaagtacacg
    33901 tttcgcatgc ttgtcgtcaa ctagcttccc accaaattct aaatataatt tgtcatagtg
    33961 gttcactcgt tccaaaatat acgctgactg ctcttcaata tatttttctg aatcaaaacc
    34021 aatttttttc actaggttcc ctccttaagt actaaagcat tttttcattt ttttgaggat
    34081 tcgtcaactg gaagagcgaa attcctcaaa aaaacaaaga aaatggttta aaccaacttg
    34141 tctagatagt tattcattgg tatgatagtt tttgataagg aaggtgctac atgaaaaaaa
    34201 gacagaaaaa gaaaaacgca tataaacact atatccgttc gatttttacc ggttatgaaa
    34261 gaatgcttga agatcccgaa ttggaacaat tgacgtttac ttatctaaac gaagaaacgc
    34321 agctaactcg tgatgagcat cagcgcattc atttcacaac aagagatctg cctagtaaat
    34381 aaaaaataag ataaaggtca tcggattcga ttctgtccta tcagatggaa agactagttg
    34441 atcgaaaaaa aggctgtacc aaattttggt gcagcctgtt ttatggagca ttgcccgctc
    34501 ttttttataa caatttttta cagaaaatgg tactattgaa gtattaataa gtgaaaaaca
    34561 gatgagtaag aggaggcaag tagtatgaaa gagccagata caaatgcaaa ttatgagcca
    34621 gacgaactag aggagacgaa tgcggatcag gatacaggac aagaatcgtc ttctttttac
    34681 gatatcaaag aaaaagcaag catgaatctt tcccaattat tagaagactt acaggctttt
    34741 gaaaaagctg tccgcgaaga agatatccct gagatctacc gtttatacaa tggccgattg
    34801 aatgaagaat taaaaagaag ctcaaatgaa aatcacgaga tcgatcaatt gctgatgcgt
    34861 aagatccatg atcgtttttt acaggaattt ccttttatgg aacaagtaga aaacatctcg
    34921 ccaacgatga gctattacaa aatcggcact tattaccatg atcggcccac ggtcggtatt
    34981 gatgcaagtc tgccagaaat ttttgttttg cctaagatcg atgaagagtg ggagaaatat
    35041 tcccaaccgg agtcaacgga ctatgacaaa aaaatcaatg agctagacgc aaaggtgatc
    35101 actgctcaga cagaaattga acgtttagat gaacaaataa aagaaatcaa tcgacaaatg
    35161 actgatttga acgacaataa aggattcttg aatcgtaaaa aaatcgagga agaaattcaa
    35221 gaattagaga agaagaagca agtactatct aatgaaaaat taggctggct tccttatatt
    35281 gagacgcctg aaacaatcca gcagcaaaaa gaagcattga agcaagaagc aagagcagac
    35341 cagcttcgtg cagccatcgt agaaaaagaa caaaggcaaa tcagacgcta tttcggtagc
    35401 aaagagggat tcggtcaagc aatccatgaa ttcttgatga attatcttgg caatgagaat
    35461 cctaataatc aatctaatga aggaggttcc gagtatgaat gaacacgatg aagcagaatg
    35521 gacaaaaaat gaagaacaaa cagaagatca tgaagaaacg aacacttcat tggaagaaca
    35581 aacaagtaat cctctggatg acacagaaga aatccctatg ctagaggaaa caaaaataca
    35641 cgaaaaagaa aaagtaactc cgacgaatac gaatactgca gaaaacaccc atgcttacga
    35701 aataactgaa aatcccgggt atttagaagg aaaagagcaa gatcatcaag atatcgtcag
    35761 tttgattgaa acagcggaag cagaattagc ggatttacgt atgagaaaag atttgatcga
    35821 atcagatttt ccacaattat tagaatcata tgatcgtttt atattgaatg aagaaccaat
    35881 ctccacgatc ggaaagacaa gcctgatcga atacttcacg tatgaattac tgaaaccgtt
    35941 gaatgatatt ggtctggaac ggtcaaattc agcttatgac acatggaaaa caagacattt
    36001 ttcgatcaat tatacgttga atggacaaaa cgaattagtc ttttcctttg tattaccgac
    36061 catcgatcaa cgataccaag tggaatcgat gagtctccta aacgtatcac cagagacaat
    36121 ggaaatcaat gtccaagatg accgggtgct ttctttgatc cgacactggt cagtggatcg
    36181 agtattctct gcagggcaga tcacgatatt caatcacaaa ttgaatcaat tattagccca
    36241 tgcaagaaca cttggtttta ccgttaatca gacattacta gacaatacga agccacttcg
    36301 tttgaatctt cagagcgaat ttgaattgac gaatgaagta ttggatgata tttttatcgt
    36361 ggcaatgaaa aatccatcct acgatatgga aaagatcaac gaaactactt atcaagtacg
    36421 attagataaa ggacagtctt taacgataac aacaaacgaa aaagatcaaa cagtcttgtc
    36481 gatctcatct ggagactacc cacgatctgt cattgatttc tttatcaatt acgaattctt
    36541 ggtcccatta atggtgagaa agtcctgatt ggataagttg gattaccaga tgtcattcag
    36601 ataattctgt tccaaaggac ttgcggcagt tatccagaat aattgtcaca agtcttttct
    36661 gtatgtacta aatggacgtg aataacttgc tgatgaagga gggatttcat taggaatgtc
    36721 cacaaataaa atagcacagc ttagcttatt gtctgctgct tgtgtagcag gtaggatcgc
    36781 ttttcaattt attccgaatt tccagccaat gactgctatt tttttattta tagtacttta
    36841 cttaagctta aaagatgcgt taattgtcat gagtctttct attgcgatca gcagttttta
    36901 ttttggtgtt ggaccatggg tcatcggcca atggatcagc tatactgttg ttctgagttt
    36961 gttttcaatc gtctgcttga gaaaaacagt gcaaaggaat ctatggttaa agggagtctg
    37021 tttttttctg gcgggcatgg tttacggaat aggtatgacc gtttttgata cgctgttata
    37081 tcgtttgcct caaccttgga tctattacct tcaaggggtg tcgtttgatt tgatgcacag
    37141 tataggcaat gttgtgttct ttcttgtttt tctgccagtc gtcaaacgtt tttacaatca
    37201 ttcaggagga aaaaatgaaa aaaataattt atagtttgct tgcaatgagt gtcagtatac
    37261 tcattttgac aagttgcagt acaacctata cacaatcggc ttccaaccaa aaggaggaag
    37321 taaaaacatc gcaaaaagca acaatcacgt tacaagaaaa tggtcaaaac ttttcggaaa
    37381 aagaagtgtt cttcaaaaaa ggcgatgatt tactgagtat tttgaaacga aattttgaag
    37441 tcaaagaaga taacggcttc atcacttcgc ttgaagggca ctcacaggat gagaaaaatc
    37501 aactctattg gatgtttact gtggacggga aaagtgctac tactggtgcc aaagagatca
    37561 aattgaatga tggacaatcg gtcattttca atttgtctaa actataagtt tcataaaaaa
    37621 ctgttaaagg gcgaatattg ccataattca gtgagttcag ttga
//
LOCUS       DAKCAA010000024        35855 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000024 DAKCAA010000000
VERSION     DAKCAA010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.024"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="OUE31_001311"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="OUE31_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HCU0222328.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="OUE31_001312"
     CDS             complement(2020..2922)
                     /locus_tag="OUE31_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCU0222329.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="OUE31_001313"
     CDS             complement(2919..3611)
                     /locus_tag="OUE31_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HCU0222330.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="OUE31_001314"
     CDS             complement(3654..4295)
                     /locus_tag="OUE31_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCU0222331.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="OUE31_001315"
     CDS             complement(4333..4647)
                     /locus_tag="OUE31_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222332.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5987)
                     /locus_tag="OUE31_001316"
                     /pseudo
     CDS             complement(4635..5987)
                     /locus_tag="OUE31_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5984..6916)
                     /locus_tag="OUE31_001317"
     CDS             complement(5984..6916)
                     /locus_tag="OUE31_001317"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HCU0222333.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="OUE31_001318"
     CDS             complement(6913..7689)
                     /locus_tag="OUE31_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HCU0222334.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="OUE31_001319"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="OUE31_001319"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HCU0222335.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="OUE31_001320"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="OUE31_001320"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HCU0222336.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="OUE31_001321"
     CDS             complement(12014..13294)
                     /locus_tag="OUE31_001321"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HCU0222337.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="OUE31_001322"
     CDS             complement(13313..14239)
                     /locus_tag="OUE31_001322"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HCU0222338.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="OUE31_001323"
     CDS             complement(14252..15535)
                     /locus_tag="OUE31_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HCU0222339.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="OUE31_001324"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="OUE31_001324"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HCU0222340.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="OUE31_001325"
     CDS             complement(16323..17234)
                     /locus_tag="OUE31_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCU0222341.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="OUE31_001326"
     CDS             complement(17231..17695)
                     /locus_tag="OUE31_001326"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HCU0222342.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="OUE31_001327"
     CDS             complement(17700..18398)
                     /locus_tag="OUE31_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCU0222343.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="OUE31_001328"
     CDS             complement(18385..18771)
                     /locus_tag="OUE31_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222344.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="OUE31_001329"
     CDS             complement(18918..20588)
                     /locus_tag="OUE31_001329"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HCU0222345.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="OUE31_001330"
     CDS             20771..21004
                     /locus_tag="OUE31_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HCU0222346.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="OUE31_001331"
     CDS             complement(21103..21534)
                     /locus_tag="OUE31_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HCU0222347.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="OUE31_001332"
     CDS             21613..22026
                     /locus_tag="OUE31_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HCU0222348.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="OUE31_001333"
     CDS             complement(22064..23212)
                     /locus_tag="OUE31_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCU0222349.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="OUE31_001334"
     CDS             complement(23334..23930)
                     /locus_tag="OUE31_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCU0222350.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="OUE31_001335"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="OUE31_001335"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HCU0222351.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="OUE31_001336"
     CDS             27160..27591
                     /locus_tag="OUE31_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0222352.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="OUE31_001337"
     CDS             complement(27636..28985)
                     /locus_tag="OUE31_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCU0222353.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITDPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="OUE31_001338"
     CDS             complement(29055..30218)
                     /locus_tag="OUE31_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCU0222354.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="OUE31_001339"
     CDS             30347..30670
                     /locus_tag="OUE31_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222355.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="OUE31_001340"
     CDS             complement(30853..32202)
                     /locus_tag="OUE31_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0222356.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="OUE31_001341"
     CDS             complement(32271..33224)
                     /locus_tag="OUE31_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HCU0222357.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="OUE31_001342"
     CDS             complement(33326..34516)
                     /locus_tag="OUE31_001342"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HCU0222358.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            complement(35161..35844)
                     /locus_tag="OUE31_001343"
     CDS             complement(35161..35844)
                     /locus_tag="OUE31_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCU0222359.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT        10195 a         7839 c         6281 g        11540 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggatctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaat ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact
    34681 tatatagtat gaacaattac cttttagata atgatctatt ttactctacc tgggcagata
    34741 aatacaacac aaccattgat agaagccctt tcgttaaaat caattgtatt ctgaatattt
    34801 aatttattta ttgcatagac caataaaaat acataaaatt tccatcttcg tttatcagca
    34861 atttttaatt ttactctctg aatatttctt aaaagtttta cttgttgaat tcgaaaaaag
    34921 gactgtgaca aaagtcttgt cacagtccta ttcttccgaa taaacggtgt tctcctgcca
    34981 attccgaatc acaagttaca atattcatca aacacgagaa gctatttttt gaaattgttc
    35041 cttgtgactc ggagctgaac ggcaggctca cgacctcttg gtaaacagtg ttccagaagt
    35101 aacttttacg gaaaatgatc cgaaatatct tggagctgac cacttctgtc acaacctcca
    35161 tcattttttg ttatttttga tccaattgtc tggagtaaaa ttttcatcgt caatagacca
    35221 ttccagaaaa aattcttcta agaattcacg catgaaggtt tctcttcgtt tggcttcttc
    35281 atatccgtaa tcagtattca ttttatcaga cagcaagaac agtttttcat aaaaatgatt
    35341 gatcactgtc gtgccttttc ggtaattttc tttgtccttg aatgtttgcg gatacagttc
    35401 aggatcaaaa atcgggtgcc catgtccacc gccgaaataa gcagtacgca aaatgccgat
    35461 tgctcctaat gcttcgatac gatcagcgtc ttgaacgatc ttaccttcca gagatagttc
    35521 ggccgcttca gagagatttt tagaaaagga catattttcg ataatggaaa aaatcatcga
    35581 gatctgttcc tctactattg gcaaagagcg aaggaataca cgaagctgtt gctttgcctc
    35641 gttctcattt ttaacgactt tatcatcaat cgtatcatgt aggtaagctg ctgcaagcgt
    35701 cacaaagcgg tctgcctgcg gttccgtctc caaaattttt tcagctaact tgacaactct
    35761 tttggtatga tcgctcccat gtcctgtttg atcatgcgct aattggtcca tactataatc
    35821 agcgatcact tgtaatttat ccattcgttc cactt
//
LOCUS       DAKCAA010000025        34675 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000025 DAKCAA010000000
VERSION     DAKCAA010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.025"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(326..2218)
                     /locus_tag="OUE31_001344"
     CDS             complement(326..2218)
                     /locus_tag="OUE31_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222360.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2215..3942)
                     /locus_tag="OUE31_001345"
     CDS             complement(2215..3942)
                     /locus_tag="OUE31_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222361.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3958..4608)
                     /locus_tag="OUE31_001346"
     CDS             complement(3958..4608)
                     /locus_tag="OUE31_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCU0222362.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4812..5108
                     /locus_tag="OUE31_001347"
     CDS             4812..5108
                     /locus_tag="OUE31_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCU0222363.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5300..5920
                     /locus_tag="OUE31_001348"
     CDS             5300..5920
                     /locus_tag="OUE31_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HCU0222364.1"
                     /translation="MASVLVVKGHLLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(6012..7178)
                     /locus_tag="OUE31_001349"
     CDS             complement(6012..7178)
                     /locus_tag="OUE31_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCU0222365.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7190..7543)
                     /locus_tag="OUE31_001350"
     CDS             complement(7190..7543)
                     /locus_tag="OUE31_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCU0222366.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7671..8693
                     /locus_tag="OUE31_001351"
     CDS             7671..8693
                     /locus_tag="OUE31_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HCU0222367.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8712..8873
                     /locus_tag="OUE31_001352"
     CDS             8712..8873
                     /locus_tag="OUE31_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222368.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9132..9566)
                     /locus_tag="OUE31_001353"
     CDS             complement(9132..9566)
                     /locus_tag="OUE31_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222369.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9676..11535)
                     /locus_tag="OUE31_001354"
     CDS             complement(9676..11535)
                     /locus_tag="OUE31_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCU0222370.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11653..12813)
                     /locus_tag="OUE31_001355"
     CDS             complement(11653..12813)
                     /locus_tag="OUE31_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HCU0222371.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13120..14544)
                     /gene="araA"
                     /locus_tag="OUE31_001356"
     CDS             complement(13120..14544)
                     /gene="araA"
                     /locus_tag="OUE31_001356"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HCU0222372.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14560..15258)
                     /locus_tag="OUE31_001357"
     CDS             complement(14560..15258)
                     /locus_tag="OUE31_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCU0222373.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15215..16876)
                     /locus_tag="OUE31_001358"
     CDS             complement(15215..16876)
                     /locus_tag="OUE31_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HCU0222374.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17094..18494
                     /locus_tag="OUE31_001359"
     CDS             17094..18494
                     /locus_tag="OUE31_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HCU0222375.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18746..19825)
                     /locus_tag="OUE31_001360"
     CDS             complement(18746..19825)
                     /locus_tag="OUE31_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCU0222376.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19911..20870)
                     /locus_tag="OUE31_001361"
     CDS             complement(19911..20870)
                     /locus_tag="OUE31_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCU0222377.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20882..22393)
                     /locus_tag="OUE31_001362"
     CDS             complement(20882..22393)
                     /locus_tag="OUE31_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCU0222378.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22415..22978)
                     /locus_tag="OUE31_001363"
     CDS             complement(22415..22978)
                     /locus_tag="OUE31_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HCU0222379.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22984..23847)
                     /locus_tag="OUE31_001364"
     CDS             complement(22984..23847)
                     /locus_tag="OUE31_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCU0222380.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23861..24757)
                     /locus_tag="OUE31_001365"
     CDS             complement(23861..24757)
                     /locus_tag="OUE31_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0222381.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24932..26221)
                     /locus_tag="OUE31_001366"
     CDS             complement(24932..26221)
                     /locus_tag="OUE31_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCU0222382.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSSFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26193..27710)
                     /locus_tag="OUE31_001367"
     CDS             complement(26193..27710)
                     /locus_tag="OUE31_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCU0222383.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27908..28798
                     /locus_tag="OUE31_001368"
     CDS             27908..28798
                     /locus_tag="OUE31_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HCU0222384.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28871..29695)
                     /gene="nadE"
                     /locus_tag="OUE31_001369"
     CDS             complement(28871..29695)
                     /gene="nadE"
                     /locus_tag="OUE31_001369"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HCU0222385.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29707..31179)
                     /locus_tag="OUE31_001370"
     CDS             complement(29707..31179)
                     /locus_tag="OUE31_001370"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HCU0222386.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31816..32178)
                     /locus_tag="OUE31_001371"
     CDS             complement(31816..32178)
                     /locus_tag="OUE31_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCU0222387.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32401..33153
                     /locus_tag="OUE31_001372"
     CDS             32401..33153
                     /locus_tag="OUE31_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCU0222388.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33293..34216)
                     /locus_tag="OUE31_001373"
     CDS             complement(33293..34216)
                     /locus_tag="OUE31_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0222389.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34231..34503)
                     /locus_tag="OUE31_001374"
     CDS             complement(34231..34503)
                     /locus_tag="OUE31_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222390.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10234 a         7215 c         5982 g        11244 t
ORIGIN      
        1 gaacaccgtt taccaagagg ttgtgagcct gccgtttaac tccgagtcac aaggagcaat
       61 ttcaaaaaac agcttctcag gtttgttgac tattgtgact tgtgaccgag gagttggcag
      121 gagaacaccg tttaaggaag aggttgtaaa atcagcggtt tgacctgagt attagagata
      181 caaaacggaa aaatagcttc tcatattttg ccgttttttg agctaatacc gaaggacagc
      241 tgattgaaca ccgtttattc ggaaaaaggg actgtgacac gacttttgtc acagccccta
      301 aaaaaaataa taaatttgta ctattctatg aagcttcttc ttcagaaaac tgactgttat
      361 aaagatctgc atagaatccg tctttttcca tcaatgtatc gtggtttcct gtttctacga
      421 tcgaaccatg attcatcaca ataatgttgt ctgcatcgcg tattgtagac aagcggtgag
      481 caacaacgaa acttgtccgg ttttccaata ggcggttcat cgctttttga atcagtattt
      541 ctgttcgtgt atctacacta gatgttgctt catcaaggat caggacatct ggatttgcta
      601 agaatgcccg cgcaattgtg attagctgac gctgcccttg cgaaatattg cttgcatcct
      661 cgtttaatac agtgttatat ccttctggca atttacgaac aaaatcgtct acgtgagcag
      721 ctttagcagc ctcaatgatt tgttcgtctg ttgcatcgtc gttcccatat ttgatattgt
      781 catagatact tcctgtaaac agccaagtat cttgcagtac cattgaaaac tgtgcgcgca
      841 attcatcacg tgaaagatca cgggtatcta caccatcgta acgaatacta cctccagaaa
      901 catcgtagaa ccgttcaaga aggttgatca gtgtcgtctt ccctgcacca gtcggaccta
      961 caatagcgac catctcacca ggtttgacat ccaagttaaa atcagtcatt agcaagttat
     1021 ctggtgtgta gccgaattga acattttcaa aacgaacttt gtatggtgta tctttttctt
     1081 ctggaaggcc agatttttca ttggacatct cttcttcatc caacacttca aatacccgtt
     1141 cggctgaagc aactgttgat tggatagtgt tcatcaaact tgcaagttga gtgattggtt
     1201 gagagaactg tgttgtatat tgcaagaacg cttgaacatc ccctaatgtc atgttcccat
     1261 ttgcaacttt tactccgcct agtacagcga cgaacacata gcctagattt ttaacgaaat
     1321 tcatcaacgg catgatgatt gccgaaataa attgagcttt ccaaccagcg gcatacagat
     1381 tctgattttc tttttcaaat acttcctggt ctttttcagt atgattgaat gttttaacaa
     1441 tggtatgacc accatatgtt tcttctactt ggttattcaa taaacctaaa cttttttgct
     1501 gatctgcgaa aaacacttgt gatttcggcg ctacgatcat cacgatgatc aagcttaaag
     1561 ggatcatcaa taacgcgact aacgtcaatt gccagctgat tgaaagcatc atcacgatga
     1621 ccccaatcaa tgtgactgca ctagttacaa attgagtcaa attttgctgc agcgtgcttg
     1681 cgatgttatc catatcattg attgctcgag acatgatatc cccatttgta tgtgtatcat
     1741 aataggaaat cggtacacga ttcattttgg cttccaaatc atgacgtaat tcataaactg
     1801 ttcgttggga aacacgtgtc ataataaatt gctgtaaaaa gttgaataca gcagaaatca
     1861 aatacatcac gattactgtc gcaatgatct gcgcgatttt atcaaagtct atcggaaatt
     1921 ttgttacttg ttggccttgt tgcatctgtt gagcgccagc cattacacct ttgaatattt
     1981 ctgtggttgc tttccccaag acctttggtg tttggatttg gaagatcacg gctgctattg
     2041 ctagtacaaa tacagcgatg atcgcaacca tacgtttaga catatagcca aacaatcggc
     2101 gtaccgttcc ccagaaattt ttaggctttt caccttttac accgagattt ctgccaggtc
     2161 caccatgtcc tggaccgcct gctggtccat gagagggacg tgtgtttgtt ttactcatgc
     2221 taagtcctcc tctcttagtt gtgaatgaac gatttcttga taagtttcgt ttgttgctaa
     2281 tagttcttca tgtgttcctt tgccaaccag ttttccttca tctagcacaa ggatcatatc
     2341 tgcatccatt actgtactta ctcgttgagc aactaaaacg gtgatacttt ctttcatatt
     2401 cgttttcaat gcttggcgaa gattggcatc cgttttgaaa tccaacgctg agaaggaatc
     2461 atcaaacaca tagatatctg ctgttttgac taatgcccgt gcaattgcca gacgctgtct
     2521 ttgtccacca gagaagtttc ctcctccttg ttccacatgg ctatctaagc catcttccat
     2581 ctctgaaaca aaatctttag cttgtgcgat ttctaatgct ttccaaatca tttcatctgt
     2641 tgcatccggc ttaccatact gcatattgtc tcggatcgtt ccagagaaca gaactgcttt
     2701 ttgaggaaca aagcccatta attctcgcaa attatattga gtcatgtcac taatgtccgt
     2761 tccatttatt tggatcgaac cagattcgat gtcatataat cgagggatca aattgactaa
     2821 ggtcgtttta cctgaaccag tcccccctat gattgcgacg atctcgcccg acttggcttg
     2881 gaaatcaata tcttccaatg caagtttttc tgctccatga tatcgataat tgacatgatt
     2941 gaaggccaat gttgcgtttt ttccagcaaa agaaactgtt ttaggatttt cagggtcatg
     3001 gataccgatt ttttcatcca acacttcatt aatacggtca gctgaagctt gtgcacgagg
     3061 caccatgata aaaatagcgg aaagcatcat aaagctgatc aagatctgca tcgcataagt
     3121 cataaatgca atcagattac cgacttccaa agtcatatct gctatgtagt gtccaccaaa
     3181 ccaagtgatt gctacgtttg taccgctcat gatcaatgtc atcattggca tcatcaatgc
     3241 gacgatcgta ttaactttga ttgccgtatt tgtataatct ttattcgcta aatcaaaacg
     3301 attttcttca aagcgtgtct tatcgaatgc tcgaatcact ctgacccctg tcaatccttc
     3361 tcgaaatacc aggtttaaac ggtcagtttt cttttgcata cttttgaata atggaacagc
     3421 aaagtacatg attccgccga tcaaaataat cattactggg atgacaacta agaagatttt
     3481 tgtcaactga tgatcttttt gataagcaag tatgctcgcg ccaatcaacg tgattggtgc
     3541 attgatcatc atacgtaaaa acatttgtgt aaccatttgg atttgagtca catcattggt
     3601 cgttcttgtg atcaaagagg ccgttccata tttatcaaac gcatcttttg tcagactctc
     3661 tgatttttta tagacatccg tacgcaattg cttacccagt ttctgtgatt cacgagtagc
     3721 aaaaaatgta tttgcgatag cagctaagat actgatcaaa gaaaagccga tcatcacaaa
     3781 acctgtatgc caaatataat cgacatctcc ttgcgctacc cctttatcaa taatattgga
     3841 ggtaagtgtc ggcaaatata aatctgccag tacttggatc accatgaaaa ctgcagctgc
     3901 aattgctgaa gtcaaggaga tccgttttac gatttttagc atctagttcc cttctttcta
     3961 tttatatact ccgtttttca gccaagaaag tttcaaattg aattcactga ttgcttgctc
     4021 tactgagtaa tcttcagatg ttgaaaataa gcgatacgaa tgcgcaattg ttgtaaatac
     4081 agtattcatc actaattgga tcagtaattc caattcatga tcatttttta ctttcagctt
     4141 cgtccgatcg atcaattcaa gcaactcttt tgcatcttgt ttgtgttctt tatgtggatc
     4201 gtgaggcgtt ttttggcgac tcgtatgagg agcgactttt cttgaggcac ggtaatccat
     4261 gttcataaac aagttacgat aaaaagaagc attctcgcct tccaaaatct cataaatcat
     4321 tttagaaaaa taggattcga atcctttgaa tagatcacca tcggattctt tcattagttg
     4381 taacatatct ttagagctgt cacgtctcat tgtctcaaag taataaaaat aaagatcctc
     4441 tttatcttca aaatactgat agaaactgcc tctagggata tccgctaatt tgacgatatt
     4501 agcaatcgaa gcttctttta agggtactct agaaaactcg attctcgcag cctcgattag
     4561 tcttttttgt ttttctttag gcaaatggaa aaatgtctgt gtcggcatat ggattctcct
     4621 ttctttcaag atgacacatt gtcatatgac gctatgtcat tataacacct cctacctgtt
     4681 ttgcaagaca tttgcatagt ttttttcatt atcatccgat acattaaaaa agtgataaga
     4741 ggaatccttc catttgaatt aatgagagtt gcccattaaa atagccacat actaaacaaa
     4801 ggatgagata aatggcccaa tcaattagtg tccaagactt caataaattg cctctcgatg
     4861 ctgacagcat cgttttagat acaagaaata ccttagatta cacaaaaaac cacttaagcc
     4921 actcgctttc tatccccgct gctatcttgc caagacaatt aaaaaatcta gatccaaaga
     4981 aactttatta tattctaagc tatacaggca ggcgatcaga agcattagcc gatcaactta
     5041 ctgctaatgg ttttcgtgct gtttatatca ttggtgggat ggaagctctt cagtcgagtg
     5101 ttgcttgaat attgcttgtt agattcaaaa gaggctgtga caaaaaatcg tgtcacagcc
     5161 tcttttatac cctgtctttt tttagttatt tattcttcaa ccttatcaat atgacttgat
     5221 agccttttct ttttcgagta aactgatttt gttagtcata gttataacaa tcatagcaat
     5281 aaaaggagaa ggtaagcata tggcatctgt tttagtagtc aaaggtcatc tcctaactgc
     5341 agaagaatcg cgcacagtta aggcattgac gtctttttta acaagttata aagaaaatca
     5401 tccagatgat gaagtgactg ttttggaact ttatcgcgat gatattccgg aaatcgatga
     5461 agaattatta tcaggttggg aagcattacg tgctggtgca gaattcactt ccttatcaga
     5521 aagtcaacaa caaaaaattg ctcgtttcaa tgaattgact gatcagttcc ttgctgctga
     5581 taaaatcgtt atcgcaaacg ccttatggaa tctaaatatc ccaacaaaat taaaagcttg
     5641 gttcgatacc gtcaatgtag ctggaaaaac gttccgctat acagaaaacg ggccagaagg
     5701 attagtgaca ggtaaaaaag cactgcacat ccaatctaat ggcggtgtat acaacggaca
     5761 agactttgcc tctcaatatg taaaaggtat tttaaacttt gtaggcatcg atcaagtaga
     5821 tcagctattc atcgaaggaa tcgattatga ccctgaccgt gcagatgagt tgatgcaaaa
     5881 tgcattagat aaagctgctg ctttaggtaa atcattttaa aaattgagat aaatgcatac
     5941 aaaagagaca gaggaaaaaa tcttcaaagc agcatttgtg ccttggatat tttcccatct
     6001 gtctcttttt gttattcttt ctgctttttc aacggatttt cttcataaag agaagagatt
     6061 gttgtgtacc attcaaaaac atgagtaatc actactttag ctgctgcata aacaggaatc
     6121 cccaagatca caccgatgat tccgaacaat ttcccagaag tcagcagaac taataaaatc
     6181 gttactggat ggattgctaa ctgattccct agtactaatg gagagatcaa gcgtccttct
     6241 attgtctgct ctactgcaaa aacgatcagt actttgatga tcatgaatgg acctgctaca
     6301 atggctaaaa agatagccgg aatcatcgct aaaaatgatc ctaagtaagg gatcaggttt
     6361 aaaaaacccg caataatccc caacgtgaca gcatactcta aaccaatgac cgcaaaacca
     6421 atcataaaca tgattgccac agcaaaagcc acagttagtt gtcctcttat ataagaagaa
     6481 acttgactat tcatttcact cagcacattc aacgtcggtt tttgcatgcg tgtcggtaaa
     6541 aatttgacaa aataaggtgc taattgttta ccgtctttca atagataaaa taagataaac
     6601 ggcatcgtca gcagagccac taaaatagtc gctaccgcgc cgacaaaact tccaagactc
     6661 tgaactgtac tcttagatat atcttggatc atatcgcctg ccgaattcat gaacttatca
     6721 cctgctgttt ccaactgttc gcgaaattgg ttgaacagcg ggtcccgcaa aatctcggtt
     6781 aatttattat caatcgtatc tacatattga gggaagttac tgatgaagct cactgtttgt
     6841 tcctgaatct tagggatgat cactacgctc ccccatgcga ttagtgcaac aaccaaaaca
     6901 aacagcccaa tgatactgta aagccttggt acttttcgct tttcaaagta atcaactacc
     6961 ggattcatca agtaatacaa gattcctgct aaaatgatag gcagacctac gattgctaaa
     7021 aattgccaga ttggtgcaaa caaatatgaa acttttgtaa ataaaaagac gatcagcaat
     7081 attaacaata caacaagtaa ggctgtgact acttgattat ttaaaaacca gcgccaaaac
     7141 cacgataccg gtctgttctt cttatttttt ccttccataa ttcctcctgt tagttataaa
     7201 aaatttggct tcccaaacca atagcaggca gtctatgcgg atgaagatag attccatttg
     7261 caatttgtcc ttcttctgga caagcatcaa aaatcaatga tacgtgagct actgtcttta
     7321 aattcccatt ggccatcgga ccgacataat cgatcgtata tacctgatca tcaaaagcaa
     7381 ttgttccgcc tgctttcaaa gaaaaaggtt cgtcttttga tacttcttga atcaccgaat
     7441 attttcgtaa ggcagctgtt gctgttttat cgaacaaaat cagcatgggt tcttccttgt
     7501 ttattgcttc tgtcccaatt tctgtaatct ttgcctgaat cattgcactc tctcctttaa
     7561 ttgctttcaa aaacagtata acacattctc attctttagc cgtgtggaat aattatgtga
     7621 tagaataaaa acgaaaacta tttcattaca attaggagga atcagctcat atgatcgaaa
     7681 agataatttt aggaacctat acgcgtcgcg aaagtaaagg aatctatacg atcgaccttg
     7741 atacagaaaa agaagaatta gccaaccttt cattagctgt tgaagaaaat agccctacct
     7801 atgtagcaaa aagtaaagct ggcaatcttt acacagttac tagtgtggat ggattaggtg
     7861 gtgccggtgc gtacgataag gattttcatt ttttgaatgc ggtaacagag tctggcgctc
     7921 ctttgtgtta tgtagcggtt gatgaagcac gtcaattact atacggggcg aactatcata
     7981 aaggtgaagt aaatgtctac catatattag gagatggcga actgaaagca gcagattcaa
     8041 tattccatca agaagcgaca ggtcctcata aaaaccaaga tcatgcgcat gtccactata
     8101 cggatctgac tcctgaccaa cgattagtcg tatgtgatct tggtacagat cgtgtgtata
     8161 cttatgatgt gtccgaaaac ggcaaattga atcttgtaac taccttcact gcagagccag
     8221 gaacaggccc tcgccatctt gtctttcatc caaatggaca attcgcttat ttatttggtg
     8281 aattagacag cacagtccgc gtgctttctt ataataaaga aacaggtgct tttgaagaat
     8341 tacagaaaat atcgaccttg ccagaagaat tcgacggtga aaatggaggg gcagctatcc
     8401 gcatttcaaa tgatggcaag ttcctttatg cttctaaccg aggacataac tcgattgctg
     8461 tattcgcagt ttttgaagat ggttcccaca ttcaaaacaa gcaaatcatc tcaacagaag
     8521 gggattttcc ccgcgatttc gcactagatc caagcaataa ttttgtcgtg tgtgccaatc
     8581 agaacaccga taatctgaca ttatatcgcc gtcatcctga aacaggatta ctggaattac
     8641 tgaaaaaaga tgtctatgta ccagaatgtg tctgtgttta ttttgatcgt tagtaagaaa
     8701 aggagaatga aatgaatcag caagacgtat tagacagact acgggaagaa ctaaatattc
     8761 ctttctttga tgggaaaatc gaagataaag agtatagcga agaggaatat cagaaactca
     8821 aagccgattt acagaactac tttgaacaat atgtacagaa tgtagaaaac taatcagctt
     8881 tccatactat ctgaaaagaa catcaggaca agacttttcc gtctatcctg atgttctttt
     8941 ctacaaataa aaaaccgccg agatggttag actcgacgga aaaggagtat ttactcgatt
     9001 ttgagtaagt acaaggttgt tgttggttat aggtatgtca ttatcataaa ggattttgat
     9061 cactctatca taaaggtaat attacattta tattagataa ctctagtttt tattgttatc
     9121 aaagatttct tttatttttt caacaacaaa ttagtcattt tttggatggc agctgtcaat
     9181 tggtctgtcg cttggtcttg ttttgcttca gatgtattga atagatcttc atctacccct
     9241 gattcaagat cgatactttg gatcatttct tcacagcctg ctacatatga aagataagct
     9301 ttttcaaaat ttttatgaat gcccattgct tttgctggtg gacgcaaagt actgactttc
     9361 ataagcattg cccgatattt ttttgttcct tcttcaaata acaggatgat ctcttcaaga
     9421 gtcgatttgt ccagttcact tgtttttcct tcatcaattg cgtttctgat cacttcatat
     9481 ttcggatgca ttccttctcc gattgcttct gtttccttga cgatttgatc gatggactgc
     9541 acataatagc caatattcgg taacatgttc gttttcctac tttctccatt gttgttatta
     9601 tttattctac ttgtttttat cctcaaatga caagtacttg aaaaaattta atggtttcta
     9661 tacagctcgc cattcttatt cgtgctcaaa gaaaccatct gctaaactat attgtttccc
     9721 tgcgacaatg tcatattgga tcaattgata ttcgtcgtaa atctcttgtt gcgagcgatt
     9781 gaattgcgct tctttatacc actgtccgtt ttgatagtac agttctcgtt caaacgccgg
     9841 aagttcctgt tctaatgata aaagcagctg ataaaagcca tttgttgtct gattcgtctg
     9901 ttccattaga ttcgctgcaa aataaaacgg actggtgatt gcatcgtgag tcgtttgctt
     9961 ttctaattct cctttactgt cgaacataag aaattgtgtt tcatgcaatg tttgtttgtc
    10021 attttttgct tggatcgtat ctgaatagat ccctggaaga tgatcccccc aaaaaacaac
    10081 taaagtcctt ctagaaagat tcttcaattc ttccgtgaac tgcttcagtg ccgtgctgct
    10141 ataggaaata tcttgcagat aattctctaa gtcaagtgtc ccacttccat ctgaagtttt
    10201 tgcaggatag tctagattat catactttcc atcgtagggc atatgtgtct gcatcgtgac
    10261 taaatgaatg aactgaggtg ttttttcttc cttgagaagt gtcattactt ctttgtaagc
    10321 tgactcatca gaaatatatg gattattctc tatcgtatcc gtataggtca tcgtacgctc
    10381 gctgatgaac tggtcaaatc ctaatgtctg ataaacatcc tctcttttat acatcgaagt
    10441 attgtatgga tggatcgctg tcgtctggta tgattgtgcg tttaacgctg aaacgataga
    10501 aggaagctga tccatttttg gtacaagcat cgtgtaaggg gtggtgagtt gcgcattaaa
    10561 taacgccata gaaaaaccag tcaatgcttc aaattcgata tttgctgttc caccgccata
    10621 gttttgagaa agcatattgc cactatatgt ttgatcagct acttcataat aatctgccaa
    10681 tggctcacca gatacttcta cgccgtttaa tcgactagga tctgagaaac tttcactcat
    10741 cacgaacacg atgttcggcg actcttcctc tacagtttta tttttttcat cggctagctt
    10801 ctggtatttt tcagtgattt ctttgatctt ttctttcgaa tatccttcag gttcatccat
    10861 tggttctacc ttcagattgt acaaaaaccc accgataaaa ccagtgttat agtagttcat
    10921 tttctggctg taaggtatcc atagtgccgt tttattatat gcttttcgca acaaattatc
    10981 gggattgttg aaattactga tataccctag cagtccaatt gccacaagca gtgtcgttaa
    11041 tcggatcaat tggaatcgcc ttcctttttt caggcttcga aacatgtacc agcaaaacaa
    11101 tcctatcacg gttcctgcgg cagctaagat cactgtaaac agcatagtgc cggtcatatc
    11161 tttcagcaat ccgatttcag tgatcatctt caaatcgtct ggataaatcg gttcttgccg
    11221 ataactcatt ttcatataat ttgcaaaacc taatacaccg atggctacga catacgtaag
    11281 ggaacctaaa gggacagatc ctgctagtgc aatcagaaaa ataagaataa tcagcaagac
    11341 gagacaggct aagaagaatt tttccgtatg ccaagaaaaa gcaaatttca acgcaaggtc
    11401 tacggataga tcattttgac accactgcaa aaataaatta ctaaaaacaa caagaaaaaa
    11461 gatactgatg attgctgctg ttccttttaa aatctttttc tgtttggtcg aaagtctgct
    11521 tatatatctt ttcaaatgct tgctccttca tttctatcaa taaaagaatg ttgcttctct
    11581 tattttagtt gtacgaaatt cgaaagtaaa gaacggaaag aagaattaat gaaatccaaa
    11641 tattctcttt ctttatggcc tttctggttt ctttaataag cggacctttc gtactccaga
    11701 aattttttct agctgttgtt tcacttgatt gagctgttca aaatcagtac tgtctatgtc
    11761 aatcaatatg tagacatgct cattcttatg gttacgcgat atatctgcga tcgctagctc
    11821 gttctcattc agcagagaaa atatctctgc taatatattg gttttctttt gataaaatat
    11881 agtgaatcga aacggcgctt ggaaaaacat tcgtgcggat ggataattga ccgcttctct
    11941 aaccgtaccg aacaaaagat aatcttttaa ggcttcaact gccaaacgtc cgctgtctgc
    12001 caaagcttcc tgagtcgatc cccctagatg aggcaacata agtatacggt cattttctaa
    12061 gaactcttct tctggaaaat cagtcaagta tttagccaga tgttgttttt ccaatgcttg
    12121 cataacagca tatttatcaa caatttcact tcttcctaca ttgataagta cagcatcttt
    12181 tttcattttt tctatattcg cctgatcgat caatcctttt gtatcttctg tcaacggcag
    12241 catgactacg atgtaatccg aggtagaaag aactgtttct aaatctgctt gccgaacata
    12301 atccaactgg gcatcgcgga tagaataacc caagacatcc atccctaagc tatagcaact
    12361 tagcgctact tttgtgccta tcgctccaag accaagaaga ccgatggttt tgccttgcaa
    12421 ttctcgtccc acataagcac ttcttttgtt ttctgcctgt tctaaaatat taggacctgt
    12481 tagtgtttgt accatacgac ttgcttcgat tatcggacgg gaagataaga gcaaacagca
    12541 caaaacaagc tcttttactg cattagcatt tacacctggt gtattcatga cgatcgtccc
    12601 gttttcagaa gctttttcaa cgttgatcgt gttcacccca acaccagctc ttgaaattgc
    12661 tagcaaatct ggtgtaagcc attcatcttt cactttcgta ctacgaataa ctattccttc
    12721 ggctggcaaa tcatctatta ttttgaaata ttccccttgt aacttttcta tctcttgttc
    12781 tggaatagca tcaatcaaat gaacgtgata cataaaaccc cctccttact aacaagtatc
    12841 tcgaaatttc tgcaattaga caactgttta ccatttgact tcctagaagc aaaaagagca
    12901 gttagagcag agtaggctga gtgataaaaa taaggctatg acaagttact gccataagcc
    12961 ttattttcga gagcaaaata ttgagggtga gatatcttga taaatggtgt tccgttagct
    13021 gacattgata ataagactaa atttcaaaaa agttgaaaag caaatttcgt caatctcttc
    13081 ttatttctta aaactaagtg gctttttcac aacctctttt tatctaataa ccactgtttc
    13141 caactcaact aattttgccc acgtttcaat ttgatctgtt gttagattta gcgagacaac
    13201 ggtatgatga ccgccacctg cctgaatcca tgaatggaca ccttcatgga aattcggttt
    13261 agttttccat aacacacgtg caacaggtaa attaggtgct tcagtcgttg gttcaaaggc
    13321 ttctacttca ttgatcagca gtttataatg cgtaccgaaa tctgccatcg atacgactac
    13381 cccttctcct gctttcccat caaatacaag acgcgccgga tcttctctat ctcccattga
    13441 taaaggagaa acaacgattc ttggtttcgt cgcagcaagc gtcggatcta cttccatcat
    13501 atgggattcc aagattgctt cttggccact agctagctcg taagtataat cttccatgaa
    13561 tcctgtatct ttccctcgag ccatgatttt cagcaaccga tcaatcgctg cagttttcca
    13621 gtcgccttcc ccagcaaaac cgtatccttc tgccatcaaa cgttgtacag ctagtccagg
    13681 tagttgtttc attccataca ggtcttcaaa attagtcgta aaagcgttat agcctccttc
    13741 ttctaagaaa cggcgaatac cgatttcctg ctgagcttgt acttttacat gttcctccca
    13801 tgtcttttct tcataatcac catagtcgaa ggtatacaat tccttgtact cttcaaataa
    13861 ttgatcgact tcttcgtctg atacgcgatc gattacttgt acaagatctc cgataccaaa
    13921 ataatcaaca gtccaaccaa attgaatctg tgcttccact ttgtctcctt ctgtgacacc
    13981 cacgtttctc atgttgtcac caaaacgagc cacttttatt ccaaaacttt cattataggc
    14041 tactgcaaca tccatccaat cagcaatctc tttttggatc tcaggtcgtt tccagtagcc
    14101 aacgacgatt ttattttgtt tatttaatcg agcattgatg aacccatatt cgcggtcacc
    14161 atgagcggat tgatttaaat tcatgaaatc catatcgatc gttttccaag gaatgctttc
    14221 gttatattgc gtagctaaat gaagcaatgg tttttgtaga agctttgtcc cgcggatcca
    14281 catttttgct ggtgagaaag tatgcatcca agtgatcaca cctgctactt cttctcgata
    14341 attgacctct ttcatgattt ttgtgatcgt atcagcagta actgctaatt cttgaaggcg
    14401 gattggataa ggcaattggc cattttcatt cagttcatcg accatttctt gtgcatgttt
    14461 ctttacttct cgcagtgctt cttccccata taaatgctgt gatcctacaa caaaccaaaa
    14521 ttctttttct ccaatattca acataattag ccactccttt tatttgtttt gtccgtaata
    14581 cgcatttttt ccgtgttttc gtaaataatg tttatctaaa atccgttgag gcagctcttc
    14641 tgaaaatgaa ttgagctgtc tggtaaataa attcatcttg catacttcat ctagtacgac
    14701 tgcgttcatt accgcacttt gcgcatcttt cccccaagta aatggaccgt gtccgtgtaa
    14761 aagtacccct ggaattgcta agggatcaat tttgcgttct ttgaatgttt ctatgataac
    14821 ttttcctgtt tcatattcgt acccgctgtc gatttcctgt tgtgtcaaaa atcgagcaca
    14881 aggtaccgat ccataaaaag tatctgcatg cgtcgtcccc atcgcaggaa catccaatcc
    14941 tgcttgtgcc cagatcgtcg cccatgtcga gtgagtatgg acgattcctc cgatttgagg
    15001 aaatgaacga tataaaacag catgagtagg cgtatccgaa gagggattga gtttaccttc
    15061 aatgatatga ttgtccaagt ccacaacgac catgtcgtct gctgtcatct cttcataact
    15121 gactccgcta ggtttgataa cgaaatatcg tgtttcagga tcaaaagcgc tcacatttcc
    15181 ccatgtatat ttgacgagtc cgtgtttagg caagtcaaga tttgcttggt atacttcttc
    15241 tttcagttgt tccagcattt tctatcactc ctttttcttg caattgatga atcgctgttt
    15301 tttcaatgtc gatcccctca cggtaacgtc tcataaatat ctgatagcct gctatttctt
    15361 ctgctgaagg tgtgatggtg attccttggt cttgtccaaa cacgtcttct gccaagaagt
    15421 tttctaaaga cttcccatgt cgatccatca tataggctgc taataacgcg attccccacg
    15481 ctccaccttc tccggctgtg tccatcactg taactggtgc ctccatagca gatgctagaa
    15541 tccgctgtcc aacttctggt gttttaaaaa tccccccatg ccccactaaa cgatcaattt
    15601 ggacattctc agatttcaat atatccattc cgattctcat tgcaccaaaa gcactggcta
    15661 aatggatccg catgaaattc gctaaatcaa aacggctacc tggtgtacgt acaaataatg
    15721 gccttccttc atttactcct gtaatgtttt caccggaaaa ataaccataa gaaagtaatc
    15781 ccccgcaatc cgtatcgcct tctagcgctt tgttgaataa taccgtgaat aatttatctc
    15841 tgcttatctc catacccaaa gaattggtaa attcttcaaa aatactgacc caagcattga
    15901 tatccgaaga gcagttattc gtatgaacca tgcctactag ttctcctgaa ggtgtagtga
    15961 ccatgtcgat ttccggatgg acattttcta gttctttttc taatacgatc atagcgaagg
    16021 cggaagtacc agccgaaatg ttccctgtcc ctttggctac actgttcgta gcgaccatac
    16081 cggttcctgc atccccttct ggcggacaaa ccgggattcc tggtctcaaa tttcccgtag
    16141 ggtcgatcag ataagcccct gattcgctta acttgccagc ttcttctcct gctactagaa
    16201 ctttaggcaa aatgtgatcc aagtcaatcg ctacgtgcgc tttttcgatt aactgaccaa
    16261 aaatattttt catttcttga tggtaggttt tcgttgaagg atcgatagga aacatgcctg
    16321 atgcatctcc tacgcctagt actttctcac cagtaagctg ccaatggaca taacctgcaa
    16381 gcgttgtcaa aaaattaatt tctttcacat gttcttcttt attcaaaata gattgataca
    16441 aatgagcgat actccatctc tgcggaatat tgtattgaaa tttttccgtt aatattcgtt
    16501 ctgcttcttc agtgattgta tttcgccaag tacgaaatgg tactagtaac tgttccttgc
    16561 tatcaaatgc tagataaccg tgcatcattg cactgaaccc aatcgacccg attgtcgtaa
    16621 gattctcgcc atagatttcg aatacttctg ctgccatttt tcggtaactg acgcgcagtc
    16681 ctttccaaat atcttctaat gaataggtcc agataccatt ttctagtttg ttttcccact
    16741 cataactacc agcggcaata ggagtaaaag atgaatcaat caatacagct ttgatcctag
    16801 ttgatccaaa ctcaatccct aaagatgtac gaccatctat gacatctaac atactttgcg
    16861 catttacttc cttcataatg atttaactcc ctccttctcg tcaaacctga tcaaaccgtc
    16921 tttttagtag cgcttacaat gattattgta tacttttgta cgtacatgtc aagcagttat
    16981 ttacaagaat acaataaaaa acacttgttt tgtacgtaca taagttataa aatgaaattg
    17041 cttacaaaat ctgatcaacc gccttctcga aattctagaa ggagagaata cttatgaaaa
    17101 aagaaaaaaa agtttcctca tcgtttattt atttttttgg cgcatttggc ggcattctat
    17161 ttggatatga tattggtgtt atgaccggcg ccttaccttt tttacagcat gattggggtt
    17221 tggcaggtaa agcttctttg ataggatgga tcacgtcttc ggtcatgtta ggtgcgatcc
    17281 ttggcggctc tttatctggt cttctttctg ataagcttgg acgacgaaaa atgattcttc
    17341 tttctgcact tatttttatg gctggttctg tcctttctgc atctgcccct cacaatggtt
    17401 cttattttct gattgcagca aggattcttc taggtttagc tgttggcgct gcatctgccc
    17461 tagttcctgc ttatatgtct gaaatggctc ctgctagact aaggggaaga ttgtcaggga
    17521 tcaatcaagt gatgattgct tctggcatgc tcctttccta tgttgcagat tatttgctaa
    17581 aagggttgcc tgaaacgatg gcttggcgcg tgatgttagg gctcgctgct gtccccgcgc
    17641 tgattttatt tttcggtgtt ttagctctac cagagtcacc gcgttttctt atgcaatctg
    17701 gccgcttgga agaggcaaaa agagtattga actatattcg gacaccaaaa gaagctgaac
    17761 aggaattcga acaaatccag ctgaatgtca aacaagaaaa gacaaccgga acttcttggc
    17821 atactttgtt tttagaaaaa tatcgttcct tagtcattgc cggtattggt gtagcagtat
    17881 tccagcaatt tcaaggagct aatgctattt tttactatat tccgctgatc gtagaaaaag
    17941 cgactgggca tgcagcgagc gatgcattga tgtggccgat catccaagga atcattttag
    18001 ttgctggttc tttgctcttt ttggttattg cagacaagtt caatcggcga actttattga
    18061 aaataggcgg tagcgtgatg ggactttctt tcatcctacc agctgtttta ggaactgtac
    18121 tggatgctca tacaaattcg ttgttgattc tcttgttttt atgtatttat gtcgcatttt
    18181 attcttgcac atgggctcca ctgacatggg taatcgtagg cgaaatattc ccactagctg
    18241 tccgcgggcg agcatctggc ctagcctctt cttttaattg gattggttct ttcctagttg
    18301 gcttgctttt tcctgtgatg actgcttcta tgtctcaaga aatcgttttc ggcatttttg
    18361 ggatcatctg ctttttaggg gttttattta ttcaagagat cgtaccagaa actcgtggga
    18421 aatctttaga ggaaatcgaa caaagtgcat ctaaaaaaac ttatcctaaa cgtatttcta
    18481 tccatcattc ttaaagaggt tgtgacagaa gtggtcagct tcaagaaata agaaggaacc
    18541 gcttagtttc cagtcacaag gaacaatttc aaaaaacagc ttctcatgtt tgatgaatat
    18601 tgtgacttgt gaccagttgg taggagaaca ccgtttagtg gagaggtggt gaaagaaacg
    18661 ttcagccttg agcgatgaca aaagctctca caaacattgc gacgagtaac cgtaggagca
    18721 ataagaggcg gtaaaaaccc gtctcttatt tttcgttttc tttcactgtt tcccgttcaa
    18781 ctagtacagg ttcatagaga atatttggct gtgcctgtcc tttttcaatc gttgtgacga
    18841 tccaccgtgc ggcatcttgt cccaactttt cttttggatg cgtcaatgtt gtcaattttt
    18901 tattccctaa atggcttaaa gaagaatcgt ctgttcctac gatcgatagg tcatctggaa
    18961 tatgatagcc attttctgtc aacttatcta gcattaaact agctatttga tcgttatagc
    19021 aaatgatgcc atctaaagct tgttcttctt tcaaccgttg tactgttttt tcagcgattg
    19081 tttctcgtgt ttccgtggtg aaagtaatga tatcttccgt caaaaaacgc acattatact
    19141 gttcacacgc gctgataaaa cctttcatcc tgtattttcc ttgaagatcg tcgatttttg
    19201 tgatgaacaa cagacgctga tgtccttttt ttatcaaata ttctgctgcc ataaaaccga
    19261 ctttcacatc atctaaacaa atataagagg catttaactc ttcataagca gcattgatca
    19321 tcaccatcgg aatgccttgt tctctcaaag caacataaag tgctaagttt gggttatact
    19381 gattactttt cgtaggctca acgatcaaac catctacccc ataagcaatc attttcttca
    19441 aacactcttt ctccaattcg tgatcgttat tcgtactggc taaaagcaat gaatacccag
    19501 attctcgtaa ttcattttcg attcctcgga taatcgacgg aaaaatataa tcagagagat
    19561 atgtggtgat gacaccgatc gtttttgttc tgttcaatgg tgttttttct ttcttatagc
    19621 tgtcatctac atatgtgccc gacccttttt ctttacgcag atagccctca tttaccaaca
    19681 cagcgattgc ttgccgaatc gtatgtctgc tgacgtcata tatttcttgc agcttgaatt
    19741 ctgagggaat ggttgtattt acttcgtatt cctcacgaag gatcttttgt tttatctctt
    19801 ctgcaatatc ttgatatttt gccatttgcc ttgccccttt ttatttgtac gtacatatat
    19861 cataacgagt ctgcaaggtt tattcaagca aaaatcaagg tttcttgtgc tcataaggca
    19921 tacggaacag gttcaccaaa ttctggaaat ccttgctcat tccacgtaaa gcattgcgcg
    19981 ttcgcgtgcc gattaggatt gtctaacgga tccccttttt ggttcttctc tggtcgagca
    20041 tgatagatca aaatatcaaa gcacccgtct tctgaaaccg taaacgagtt gtgaccagga
    20101 ccaaattgct tatttttttc agaagaaacg aatactggct ccgataattt atgccatgat
    20161 tcttttaata aaagattctt gtgctcatca gcccacagca ggcccatggc atagttttca
    20221 tctgttgcac taccagaata cgtaatgaat attttcccat tgcgagtaag gactgctgga
    20281 ccttcattta ctgaaaaacc ccgtttttcc cattcatact caggtataga aaggaggatc
    20341 tgcttcccct ttaacgtcca aggattatcc atttcggata gataaagatt agaattccca
    20401 gtaatttcag gatcttgttg ggcccacaca taatatagct ttccttgaga agagaaagtt
    20461 gttccgtcta aactgaaagt ttcccttttc gtttttattt gtcccttttc tatccaatct
    20521 gtattcattg gatctatatg ctgattttca agtacgaaca tgcggtgatg atgagattca
    20581 tcacgtatag ttttatgatt gcttgcagca aagtaaatat accattttcc attgatataa
    20641 tggacttcag gtgcccagat caattcactc atcggtcctt cttcatgagc ctgccataca
    20701 atcaggcttg cagcatgttc taattcattc agtgactttg cccttcttaa ttcaatcact
    20761 tggtagcctg gaaccgatcc tgtaaaataa taataaccat ctgtatgttt atatacccaa
    20821 ggatctgccc gttgccgaac gataggatta ttataaagtg tcttcatcat aacaaatttc
    20881 ctcacatttt ctttattcta attacattcc aagagtattt ttctatccct acatttaatt
    20941 cgtcatgttt ttctattgaa aaatagttta tttcaggttt tattttttct ggttcttcac
    21001 gtgtattttt gtccaacaga tcgctactgg ttaatgtgta gtgctctcct tgatctagca
    21061 aattgaaatc atgttcaatc gttatctttt gttgttcatt tgtgcgattg atcaagaaaa
    21121 tagtcagctg attgccgtta tctacgatca cactgtccac ataaggaaca ttttttatct
    21181 tttcacaatc ataaacaggg caaatgattt gttgtttcaa tacttgacct ttagcatatt
    21241 tcgataagtg ttgcatcaca taataagttg gattcctcca tgcttgtcct ttagcatctg
    21301 tcagtattaa aggtattgtg tttactaaca atgattgaca actaatcttt acgcgatctg
    21361 cgtgtcgtaa aatagccagc cctaatgaac caaataataa tgtatcttcc atagtaaagt
    21421 aacaccaatc gatgggacta ccgacttcaa aatccctatg tcttttttcc ggttgggcat
    21481 gtacattcca ttcatcaaac gctagataca ttgttttctc acttctcaaa tatcctttta
    21541 cataatcaca agtagcaacg atttcttcaa tttgacgatc gaatcgataa gcttttgcaa
    21601 ggtatgtcgc tgtatcatca cgctcatttt taggaggttt agtcaagtct tcttcatcat
    21661 acttatcaat atagttatgc aaagctaaat aatctacatt ctcataagct tcttctaatg
    21721 cgatacgatc ccattcaggg tacgatggta aacgtggcgt agagcttcca actaagattg
    21781 tttcaattga atcatccact aacttcatga cttttgaggc ttcatttgct aacctaccat
    21841 attcataagc actcttagcc cccacttgcc atggaccgtc tagctcattc cctaaacacc
    21901 ataatttaac gccaaaaggc tttttttgcc cattttttat tcttaaatca ctccagaagg
    21961 ttccttttgg aaaattacaa tattctacta aattttttgc ttcatcaatt ccttttgttc
    22021 ctaaattcac cgtgaatatc ggtttcgctt gtacatgact gatccattta aaaaattcgt
    22081 ggagtccaaa agaatttggt tctatacctc gccatgctaa atcaattttt tttggtcgtt
    22141 gttctttcct acctacagta tccacccaat cataaccaga tgtaaagttt cctccaggat
    22201 agcgaatgac acctaattct aattccttta cataagagag gacatcttgt ctaaacccgt
    22261 caccatcagc tgtttcatgg cccggttcat aaatccctgt atagacgaca cttcccatat
    22321 gctcaacaaa tgagccaaac agccgagaac tgatctctcc taccgtaaaa tcctctctga
    22381 tttttacttt cacttcttcg tccaacagct ttccctacct ttcatttcct atagtcaaga
    22441 taatagatac aagtttccat acgccaccag caaagataaa aataaaagga gggaaaagaa
    22501 atatgagcag tacaaatcct aataacaata cgcaacaaag aatatttctc aaaaaatcaa
    22561 aaaatacttt ccatgcactt tgttcaaaaa tttgtaaaaa tgtgatatct ttgttttcag
    22621 aaatcacata tatccaggat aaaagaaaca tggaataaat aagtaaaact acatatccac
    22681 taattgaaag tacgattgtc tgttcttcta ataattgatt aacaagaaaa taaataatga
    22741 tcgttaacag actaaggaac aagttcttac caaaatgttg ctttattcct tgaaagaaaa
    22801 aataaatgat atttcctgat ccctcacctt tccattgcgc cattacataa aaaacagcac
    22861 atgtagcagg cacgatagta ataacaggca aacacacgat tacccagaga atacctaata
    22921 agatgtaatc agaaaccaca atcaactgtc cataaagttt agtctcaact attttcatct
    22981 tcctcactct ttcattccag acatagctgt tccttgaaca aaatatttct gtgcaaaaat
    23041 ataaaccact agtaatggca gcattgaaat aaccgttcca gccattacag gtccataaaa
    23101 agaaatgttc tgccctgtaa ataaagctaa ccctgctggt aaagttctca tttttgaact
    23161 acttgtcaat atcaatggat aaagcaagtc attccaacta ttcatcagcg tgaaaatccc
    23221 taatgataaa agagtaggtt tgctcaatgg caacatgatt ttcaaaaaaa tattaaactc
    23281 acttaatcca tcaatgcgtg ctgcctcttc caaagaatct ggtaaagtaa taaaaaagga
    23341 acgcatcatg aagataccaa atgcagttgt catacgagga atgatcaaac ctgcataagt
    23401 atcaagcatg ccaagcaaat tgacttcaat aaatagagga atcatgaaga cttggaatgg
    23461 gatcatcatt gtcagcaaaa cgaaatagaa caaaactgat tttcctttga aacgcatacg
    23521 agcaaatgca taccccgcaa gagaatcaaa gaatacagaa gtgatcactg tccctccagc
    23581 aaaaatcact gtatttttga tgtaatctaa taaagggatc gttgtccaaa ccttaatata
    23641 gttatctagg gtatagctat ctgcaaatat tctaggcgga aatgagataa tgtctttttc
    23701 gtgtttaaaa gaagaaataa tcagccacaa aaaaggaaac gcaataacca acaatataac
    23761 tagcatacta atcgttcgaa tgattttttt accactaact gcttttcgac tattcacagt
    23821 aactgtaatc gagctttctg gtgccataca ggtttccctc ctatttcatt tgtttttctt
    23881 tccgtgacat gtacacatta gtggagatag ctatagttgc aacaatgata aacaaaaccg
    23941 aagacagtgc tgatgcatag cccaattcat aaggtgctgt aaatcctcga ctgtaaatat
    24001 attgaacagc tgtttctgtc ttaaattgtg ggccaccagc ggttgcaaca tatacttggt
    24061 caaacacttg catcgaacca atcagattcg ttaaaataca aaaacctaag gagggaacga
    24121 tctgaggtag cgtaatgtta aaaaactgct gtcgatttgt tgcaccatcc atttgagcag
    24181 attcatacaa agagggagag attccctgaa tagcagtcaa gagaatcgtc atagtaacac
    24241 caaaattctt ccaaacagtc atgatggcta ccgtcggcat agcaagggtt ggatcgcgaa
    24301 aaaattgagg gatcggcaag ccgacttgtg aaaacaagta aggaatcgcc cctacattcg
    24361 gatcaagcaa catagaaaaa ataatcgcaa ttgacgtcaa tgaacaaata actggaatgt
    24421 aaaatgtcga acgacaaaaa cgattgaatc tggtattttt agataatgct actgctgcta
    24481 ataaaccaac gataatttgt gttggcgttt cgagtacggt gaaatataaa gaatgaatca
    24541 acgaattaac tgctcgttca tcactaaata tacgtgtgaa attttcaaaa cttacaaaat
    24601 ttcttgatgt aaagaaaata ttcaaatctg taaaactaat agcaaatgtt cctaaaagcg
    24661 gtatgacagt aaataataat aaaactaaaa aagatggagt taaaaacaaa tacgcagcac
    24721 gatcaggacg attccaatat ttggtgaatc cgttcatata gtccacctca tctttcattt
    24781 tgataaaata tacaatcttg gtttaaacga atctgaataa gatatccgaa caatcgctgt
    24841 gatttttgca ataacaccta tctgcaaata ctaggtcgat cattcagata tctgtatctt
    24901 gccaacagtc tatcctgtat aaagttctgt actatttttg cagtaattga ttgatggcat
    24961 catctgcatc gttcatgagt gtctcaggat cttctcctgc taataatttt tcaatcagtg
    25021 gattgatgat atcgttattg atcgcagaga tttgggtaaa acctggtaaa tatggctctg
    25081 catagtccat ttgtttcgat aattcagata caataggatc attttttact tcttcatctt
    25141 ttgctactga atccaagtag gcaggaaaac cattttcgat actccatttt ttaccaattt
    25201 cagttgtatt ccaatatttc aaaaactcat agacagcttc ttttttatta ttatctgtac
    25261 ttgccggaat ggcatatcct acgccatcta aaatagctgt ttttttgtct gaatcactcc
    25321 cttgtggtaa ggtagtcaca ttataatcaa tctcgtttgc tttcaatccg ttatttaacc
    25381 atggcccatt gatttcaatg gctagttgac cagcattcat taaattgtcc atttcggcgc
    25441 cagaaatcga ttctggacca gtcttgtcta catggatcat tttttggatc gcttttaacg
    25501 ttttaaggtt ctcaggagac gcaaattcag acttagtata atcatcgttc actaatttac
    25561 cgccatttgc taacatccag ttatataacg gtgcagttcc atccttattg aagacaaaac
    25621 ttgatacatt tttactacta tcagttaatt ttggtgccat ttctgtcaat tcttcccaag
    25681 tagtaggtgg ttgttcagta tctaatccag cttgtttaaa caaatcatta ttccaataca
    25741 tatacatgcc ttgtacctgc atggggacaa aatactgttt accttctact tcacctaatt
    25801 caatagccgt ttctttaaaa tcagatttat ctactccatc atattcccag aaatcgtcta
    25861 atggttgtac cgctccgttt tctacatact gtgcaaaatc tggataattt aatgcaataa
    25921 agtcaggtgc ttttttagaa gaaatcgctg taggaagttt ttcattcaaa ttggcccaag
    25981 tcatgatatc catttcaatt ttgatgtttt tatcatttgt tttattaaat tcattaacga
    26041 tttcttgcaa tatttcacca tcagatgcag taaacccatt ccaaaaagtc aaagtcactt
    26101 ctttatcaga atcagattct gctgaacttc cgccaccgca agctcctaaa atacctgttg
    26161 cagctaccaa caaagagcca attaaccatt ttttaccttt cattttttgt tcctccttca
    26221 tctgataaac gacatctgac cacattccaa gatagcggtt tcaataaaca attgattttc
    26281 ccatcttcag cttttacatt tgttgaatga cttggtttta cttgttcact tttaggaaga
    26341 ttagttgctt ttgtatcaaa tccactcatt tcagaaaaat caatcactcc ctctaatgat
    26401 aattcagaca agtgaacagt tagattcatt tcttcttctc cacggttaac tgcaaatatg
    26461 acaagttctt tgtcatttat tacggctata ctttctaaat acggcacttc ttcaaaatct
    26521 tccgtcgcat agtttgctga acgaatttgt gggcttaaca cctctccttg tccatacaca
    26581 gcagcttgca taaatggata atagatcgtc tgtctccaag cttctccgtt tgtttctgtc
    26641 ctgattggtg caataacatt taccaattga gcaagacaag caatctttac tctatctgca
    26701 tgtttcaata aagtgattaa tagacagcct aatagtaatg catcttcaaa attatagtta
    26761 tcttctagta aaggaggagc aatctgccaa ggcgctgctt gctcatcttg ttccgctgaa
    26821 tgataccaaa tattccattc atcaaaggac aggttgatct gcttcttact atgtttcttc
    26881 gccttgactg tatcgcacat cgctgtcact tcagaaatga accgatccat gtctaaggaa
    26941 cgtgcaagat aatgagaaag atcatttttt tggttgccat aatattgatg cagagacaaa
    27001 taatctattt gatcgtacgc ttgatcaaga actgttaact cccaatcacc aaatgtaggc
    27061 atttgccgat tcgaacttcc gcataaaacc acctcaattg aatcatctac gagtttcatc
    27121 gccttagccg tttcctctgc taaccgtcca tattcttccg ctgttttatg tccaatctgc
    27181 caaggaccgt ccatttcatt ccctaaacac catgtcttaa ttccaaaagg gctctcttga
    27241 ccattcgaac gccttaaatc actccaataa gttcctttag gaaaattaca atattcgact
    27301 aaattacgag ctgcatctac tccacgagta cccagattga cagccatatt gatttcggcc
    27361 cccacatgct gacaccagtt ataaaattca tgaatcccaa cttcattcgt ttcaattgtc
    27421 cgccaagcta aatccaacct tctaggtcta tttgctatgg gcccaatact gtcttcccaa
    27481 cgaaatcctg acacaaaatt tccaccagga tatctaatca tgggaatgtt caattctttt
    27541 accaagtgaa tgacgtcttg gcgaaatcca cttttattag ctgatggatg atctggctga
    27601 taaatccctt catatactgc tcgtcccata tgttcaataa atgaactgta caaccgcgga
    27661 tcaactttgc ctacacgctt gacactacta atcaacattg tggcttccat aactgacctc
    27721 ctttaattta tacatgaata atacacctcg ttgaaagcgt tgtcaataat ataaatgtta
    27781 aacttactta ttttttatcg attttaatta accaaaatat taataatgat taaaacaaat
    27841 aatttaatat aacttttatt aacaaatatg ttaatatata agaaaaacct tttaagaggt
    27901 gatatatatg caactacaaa taaacgaaga atccttaccg gtatatgaag cattagctag
    27961 taaaacaagg atcaagatca tccagctact ttccaaaaaa aagatgaatg tcaaagattt
    28021 ggcaaaagaa cttggagtga gcagtgctat cacgacgatg cacgtgaaaa agctagagga
    28081 agcaaacatc atcaaaacag aaaaagtagg acaacaaaaa atttcgagcc ttcgtgtcga
    28141 taaaatcgat atcagttttc cagaaaaaat attcaatgct tttgatacga aagaaacatc
    28201 gatacctatt ggtcactata caaattatgc aattgaacca acatgcggtt tagctacgat
    28261 ccatgatttt atcgggaaag tggatgaacc acgctatttt atggatcctc gaaggatgga
    28321 tgcccgcatt ctctggttta ccagcggatt tgtcgagtat caggcaccta attttttaaa
    28381 tacagaggat acattggaga tgttggaagt ttctgtggaa atttcttctg aatttccttt
    28441 ttcaaatgac aattggcctt cagatatcac tttcagccta aatggtgtgg agctaggaac
    28501 atggacgagc cctggagatt ttgctgatat ccgcggtaaa tatacgcctg attggtatcc
    28561 agataatctt aatcaatacg gcttgctgaa gacgatccga attaccaaac acttgacgaa
    28621 tatgaatgga gaacccttgt caaacatcac gatcaacgac atccctaaag agcaagacac
    28681 ttggcatttg cgaatcgaag tgaaagacga tgccaaacat gtggggggct gtactttatt
    28741 tggtaaagga ttcggtaatt acgatcagga tatcaaatta aaagtttact acagctgata
    28801 tttttctttt ctattttata aaacaaaaac agccaatccc tatgaaggga cggctgtttt
    28861 tgctttattg ttatttccag aaatcatcca aaacggaaat tggcaaatgt cgtttatgtt
    28921 gtgtcttgtt ccaccatgct tcgatttttt cttgtgcttg agcgggaact tcttttcctt
    28981 ctagataatc atcaatttca ttatatgtga cacctagtgc gacttcatct gcaatcattg
    29041 gtttcccatc ttcaagatct gcagtcggaa tttttgtgta taatttttcc ggtgcattca
    29101 atgcttgaag caattgtttc ccttgtcgtt tgtccaaacg gaataatggc aaaatgtcgg
    29161 ctccaccatc accaaatttc gtgaagaatc cagtaatgtt ttctgcagca tgatctgtcc
    29221 ctaatacggc tcctgctctt tctccagcta cggcatattg cgtaatcata cgttgacgtg
    29281 ctttgatatt tcctttgtta aaatcgctga ttcccacacc tgcttcgctt aatacttgta
    29341 cttgtgcatc aacagctggt ttgatattta ctcgcagact aacatcgggc tggataaagt
    29401 caagagcagc ttttgcatct tcttcatctg cttgttcacc ataaggaaga cgaacagcga
    29461 taaattgata gttttcatct tttgtttctt cacgcatttc ttccatcgtt agttgcgcca
    29521 aacggcctgc taaagtagaa tcttggccgc cgctgatacc tagtacaaaa gttttaagaa
    29581 acggatattt tttcaaatat gctttcataa agtcaatact tttacgtatt tcttcttttg
    29641 gatcaattgt tggtttgaca cctaattcat tgataatttc tgtctgcagg ctcatttatt
    29701 ctcctcctat gcttctgtat gaagttctgc tacgcttttt ttcattcgtt ccatgatagc
    29761 cattttatgg ttccagcatt cagtagacag atcgactggg tatttttgcg gattcaagtc
    29821 tcgtttatac tcttcccata gtgaatctag attttctttt gtatattctt tgatttcgtt
    29881 tagtgcaggt aattcgtaaa ctctttttcc ttcgataaag atatcttgta aaactgggcg
    29941 agctgtaaag tctcgaacag ttttattgat aaacgtatgc actggatgga acatgaagat
    30001 agcttcttct tctcgagggt cttcatccca taatgtcacg tagtctcctt cagatttccc
    30061 atcaaaattt cgagtgatgc gccacacttg ttttttccct ggagtagtta ctttttctgc
    30121 attgcttgat aacttgatcg tatccatcat ttttccttca tcatcttcga tcgatactag
    30181 cttgaatact gcaccaaggg ctggctgatc ataggctgtg atcaattttg tcccaacacc
    30241 ccatacatca attttagctt tttgcatctt taaattcaaa atcgttgctt catccaagtc
    30301 attcgaagca tagatttttg cttccgtaaa tccggctgca tctaattgtt cccgaacacg
    30361 cttagatata taggccatat ctccactgtc gatgcgtacg ccttggaagt tgattttgtc
    30421 acctaattct ttcgccacgc gaatcgcact tggcacacct gatttcaacg tatcataagt
    30481 gtcgactaag aacacgcagt ctttatgggt tttagcgtag gccataaatg cttcataatc
    30541 atttccataa gattggacta acgaatgagc atgggtcccg ctagctggta tcccaaatat
    30601 cttcccagca cgtacattgc ttgttgcatc tgctccgccg atatatgccg ctctagttcc
    30661 ccagactgct gcatccagtt cttgtgcccg tctagttcca aattccaata gtggatcttc
    30721 tccgatgaca gatttgatac gagctgcttt tgtcgcgatc aacgtttgga aattgaccat
    30781 attcaacagt gctgtttcta ctaattggca gtgcgctaaa ggcccttcca cttggattaa
    30841 tggttcattt gcaaaaacta gttctccttc acgagcagaa cgaactgttg ctttaaattc
    30901 aaaattttgt aaatactcca aaaaaccttc aggatagact tctaatccac gcaagtaagc
    30961 aatatcggaa tcattgaacg tcagattctc taaataattg actaaccgtt ccaatcctgc
    31021 aaaaaccgcg tatccgtggt taaaaggcat ttctcgaaag taacattcaa aaacagcatg
    31081 taaatcagct cgacctaatt cccagtatgt ctgcatcata ttgatttgat atagatccgt
    31141 atgcagcgtc aaactgtcgt ctgggtaagt attattcatc ttgtattact cctcttggca
    31201 agttttcatt tcctacccat tataacaaaa aaaattaata ggaaaagaaa tcttccattt
    31261 tttctgaaaa agcacatgtt ttacggatat ttcttgctaa aaatgaactc catctgctaa
    31321 aactatcctt tcttattggt atttaaccta aacgagaaag aatacttatt ttattcaatg
    31381 tatccgagac acgaagaaat tagcgttttc tatttttctt acttgataaa ataagtagat
    31441 tttcctacta caatcgtagc cgttaagata ccgatgattg aacaaatata accaaatgtc
    31501 tctacaacat aatcaatggc aaaagttttt gaagcaataa tacgtctttc cttttttgct
    31561 tcttatcccc aaagaaacgg atataactta ttatgtattg aatttttttg gaaaggcgaa
    31621 ttatgacaag atataccttg cgttgaaaaa actcgcggaa aaaatatcac acgtttttaa
    31681 aaagatacaa agtaagaaag cagctgtcaa tagaatggaa acaaaaatgg cgagacatca
    31741 atcagtctcg ccttgttttt tattgtatac attagatatg gagcaggtta ccataaagat
    31801 gattattagt cgttattaaa tagaatcctt cgtatttttt tgttctatca ctacaatatc
    31861 tttatttgga cgtttgaatt gtattccggc acgttctagc tcctgtttca ctcctacatg
    31921 gactttgaca tcttctcgtg tcatttttaa aacgtgatga atcgcatagt cgatttcttg
    31981 ccttgtgatt tttttcttcg tattgatcat cacgacttgc tttttatcat atgtgtctac
    32041 caatagcagt tgtgttcgat ctaacgaaaa taatttgtaa taattaatag ccgtattccc
    32101 aaaaaagaat tccactactt taggataaaa tgtcttaata tttaaattac tattcacagg
    32161 tgtttcgatt agcttcatct cattcctctt ttctatatag tcgatttaga tccaatctta
    32221 agttatgtta ccatctttcc tagcattaag gaatcggtta caattgaacc tttaaagaca
    32281 aaaggattta ccttttatca cttaatagta taacataatt tcgtgagaaa aaaatacaat
    32341 tttttcttga ccatctcgtt acgtaaagga ttatgcttac atttgtcagg aggaaaaata
    32401 atggagtaca caataaagaa aatgtcagag atatcaggag tcagtccgag aaccttgcgc
    32461 ttttatgatg agattggact gctaaaacca gctaggatca attcttcagg ttatcggatt
    32521 tatggcaaaa aagaagtcga tcgtctgcaa cacatcttat tttatcgaac aatggcattc
    32581 aagttggatg atatccaaga ggtcttagac aatccatctt ttgaccacca gaaagcttta
    32641 atcaagcatc agcaaatgtt gctggaaaaa cgggcacaaa tcgataccct cttgacaact
    32701 gtccaacaga cacttgatat gtacgaagga ggaagaaaaa tgagtgacaa agaaaaattt
    32761 gaagggttta aacaacaaaa gttgaaagaa aatgaagaat cctatggaca agagattcga
    32821 caaaaatacg gaaaaaaaaa ggttacagca tccaatgaaa aatggatgaa tatggataaa
    32881 gaaacgtatg aagaaatgca aactgttgaa aagcagatgt tatttgatct cactctttac
    32941 ttaaaagaac cagaagatga aagcttagca gaccgtatct tccaagctca taagaagtgg
    33001 ttctcttaca gctggcctga atatcagcca aaagcgcata aaggactagg aatgatgtac
    33061 gaagccgatg aacggttcac tgcatattat gacgagcgaa gtggtcatgg tgcagcaaaa
    33121 gctttaaatg aaattatcca aaaaaaggcg taatctttta catgatccaa caaaaaagta
    33181 cacgtaaaat gacctaataa caaaacagca gacacccaag ttagattttt atgctaactt
    33241 ttggtgtctg ctccattctt tcacaagttt tttcatccta ctttaaatat attcatcgtt
    33301 gaataaacgt ataaggtatt ttcactttat cctttttttc tgtaagaaac aattgaaatg
    33361 ccatttctcc gcaagcttcc agatggtggt cgatggttgg gaaaccaaga agctcgctga
    33421 tcagcaaatt atcgcgtcca atcaccactg gtgtcttatc ttgcagatag ctttgcaaga
    33481 tgcctgctgc aaccatatcc gaatttgtaa agacaccatc aactccaagc tctttaaaaa
    33541 agaagcctgc ttgttttcct ttctctgcat ctatacaatc ccaaaaaaca agtgattcat
    33601 caaaagatgg aaaaagttga tgacatagct gcaaagtgat ttttgagtta taacttagcc
    33661 tgccacttcg ccccaacgtg atgcccaatt gctttatacc ttgctgcttc aaataagtaa
    33721 gaccttctgt aattgattgt tctcgatcaa taaagacaca gcttgcctgt tttcccttga
    33781 tttcttcaca aaaaactaga ggtccatatt tttgatatgc caataaatca tctagtgtat
    33841 tggcacgaga cgtaatgatc aatccatcga aagctttagc tgcaaattct tcaagatacc
    33901 ttcgctcttt ttctttatga tagcccgtcg gtaaaagtgt cactttgtaa tcataatcaa
    33961 acgctgcttc aatgatccca ctgatcaact gatcaaaata cggatgattg gtataaggca
    34021 gaatcactcc aatgcttttc gtttttccat aacttaactg tctggcattt gcattaggga
    34081 tataatcgac ttctttcatg accgcaagta tttctttcct tttttcctca tctacatatg
    34141 gatgtccatt gattacacgt gaaatagtag aaactgaata acctgtgagc tttgcgatat
    34201 ctcgaatgtt tgccactgct gcttcgccac ctatacaaaa agattttctt gtaaatagtc
    34261 taccacagct ggaccgcatt caaaaaactg atacattttt ccttcatgcg aaaaactgat
    34321 ccgctgcccg ccccaatata tatcttttgt caaattttcg atttcattca ttggtatttc
    34381 ttttactata ttcctattca acccttgaaa actgtacaac gttaatacgg atcccttgaa
    34441 ctcgacaaac gcataaaaat aattgttcgt tgtgccatct gttatctcta cataagtatt
    34501 cattgcaagc cctccttttg atactttgag tatagtgtat gaaacgcgtc tcatagcaag
    34561 gagtttgttt tgccaaagaa aagttttatt cctctttcat tattaccaaa gtctcttatt
    34621 ttaaattgaa tacattataa tgatactgta aatatatctt tattattagt gaatg
//
LOCUS       DAKCAA010000026        34636 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000026 DAKCAA010000000
VERSION     DAKCAA010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.026"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            591..1280
                     /locus_tag="OUE31_001375"
     CDS             591..1280
                     /locus_tag="OUE31_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0222391.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="OUE31_001376"
     CDS             1267..2475
                     /locus_tag="OUE31_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCU0222392.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="OUE31_001377"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="OUE31_001377"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HCU0222393.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="OUE31_001378"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="OUE31_001378"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HCU0222394.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="OUE31_001379"
     CDS             complement(6578..7273)
                     /locus_tag="OUE31_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HCU0222395.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="OUE31_001380"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="OUE31_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HCU0222396.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="OUE31_001381"
     CDS             complement(8472..8663)
                     /locus_tag="OUE31_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HCU0222397.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="OUE31_001382"
     CDS             complement(8684..9574)
                     /locus_tag="OUE31_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HCU0222398.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="OUE31_001383"
     CDS             complement(9561..10328)
                     /locus_tag="OUE31_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCU0222399.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="OUE31_001384"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="OUE31_001384"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HCU0222400.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="OUE31_001385"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="OUE31_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HCU0222401.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="OUE31_001386"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="OUE31_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HCU0222402.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="OUE31_001387"
     CDS             14899..15282
                     /locus_tag="OUE31_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222403.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="OUE31_001388"
     CDS             complement(15450..16208)
                     /locus_tag="OUE31_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HCU0222404.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="OUE31_001389"
     CDS             complement(16226..17044)
                     /locus_tag="OUE31_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCU0222405.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="OUE31_001390"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="OUE31_001390"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HCU0222406.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="OUE31_001391"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="OUE31_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HCU0222407.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="OUE31_001392"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="OUE31_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HCU0222408.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="OUE31_001393"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="OUE31_001393"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HCU0222409.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="OUE31_001394"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="OUE31_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HCU0222410.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="OUE31_001395"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="OUE31_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HCU0222411.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="OUE31_001396"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="OUE31_001396"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HCU0222412.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="OUE31_001397"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="OUE31_001397"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HCU0222413.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="OUE31_001398"
     CDS             27086..27385
                     /locus_tag="OUE31_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HCU0222414.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="OUE31_001399"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="OUE31_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCU0222415.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /locus_tag="OUE31_001400"
     CDS             27973..28209
                     /locus_tag="OUE31_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HCU0222416.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="OUE31_001401"
     CDS             28352..30325
                     /locus_tag="OUE31_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HCU0222417.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFTAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="OUE31_001402"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="OUE31_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HCU0222418.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="OUE31_001403"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="OUE31_001403"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCU0222419.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="OUE31_001404"
     CDS             33204..34496
                     /locus_tag="OUE31_001404"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HCU0222420.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10555 a         6733 c         6843 g        10505 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tatattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagac caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgttaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggattaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggcggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccgtc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagactat gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atgggaaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatct
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaattct tgaaaactat
    25441 atcgaacatc agcgcgaagt catcacaaga cggacagtct ttgaaaaaga aaaagcagaa
    25501 gcaagggcac acattttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaagcaaaag cgacgatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgcacagc caaaggaata ccaattatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggttagagg aatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aagatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaatag ccatcaagac taattgtgta agctagcaag
    26881 aatgaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataatcag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattggatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaac gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atatcgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt actgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaacact gtttattcag aataagggac tgtgacaaaa accgtgtcac
    34621 agtccctttt tccgaa
//
LOCUS       DAKCAA010000027        33210 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000027 DAKCAA010000000
VERSION     DAKCAA010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.027"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..479)
                     /locus_tag="OUE31_001405"
     CDS             complement(<1..479)
                     /locus_tag="OUE31_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCU0222421.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(552..836)
                     /locus_tag="OUE31_001406"
     CDS             complement(552..836)
                     /locus_tag="OUE31_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222422.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(914..1108)
                     /gene="ssrS"
                     /locus_tag="OUE31_001407"
     ncRNA           complement(914..1108)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="OUE31_001407"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(1180..2466)
                     /locus_tag="OUE31_001408"
     CDS             complement(1180..2466)
                     /locus_tag="OUE31_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HCU0222423.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            2604..3275
                     /locus_tag="OUE31_001409"
     CDS             2604..3275
                     /locus_tag="OUE31_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HCU0222424.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            3241..3729
                     /locus_tag="OUE31_001410"
     CDS             3241..3729
                     /locus_tag="OUE31_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HCU0222425.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            3742..4689
                     /gene="prmA"
                     /locus_tag="OUE31_001411"
     CDS             3742..4689
                     /gene="prmA"
                     /locus_tag="OUE31_001411"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HCU0222426.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            4690..5454
                     /locus_tag="OUE31_001412"
     CDS             4690..5454
                     /locus_tag="OUE31_001412"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HCU0222427.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            5687..7900
                     /locus_tag="OUE31_001413"
     CDS             5687..7900
                     /locus_tag="OUE31_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HCU0222428.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            7911..8357
                     /locus_tag="OUE31_001414"
     CDS             7911..8357
                     /locus_tag="OUE31_001414"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HCU0222429.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            8528..9787
                     /locus_tag="OUE31_001415"
     CDS             8528..9787
                     /locus_tag="OUE31_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HCU0222430.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(9876..10823)
                     /locus_tag="OUE31_001416"
     CDS             complement(9876..10823)
                     /locus_tag="OUE31_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCU0222431.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            11217..12509
                     /locus_tag="OUE31_001417"
     CDS             11217..12509
                     /locus_tag="OUE31_001417"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HCU0222432.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            12524..14293
                     /gene="aspS"
                     /locus_tag="OUE31_001418"
     CDS             12524..14293
                     /gene="aspS"
                     /locus_tag="OUE31_001418"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HCU0222433.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            14402..15277
                     /locus_tag="OUE31_001419"
     CDS             14402..15277
                     /locus_tag="OUE31_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCU0222434.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            15543..17426
                     /locus_tag="OUE31_001420"
     CDS             15543..17426
                     /locus_tag="OUE31_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCU0222435.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(17501..17785)
                     /locus_tag="OUE31_001421"
     CDS             complement(17501..17785)
                     /locus_tag="OUE31_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCU0222436.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(17775..18509)
                     /locus_tag="OUE31_001422"
     CDS             complement(17775..18509)
                     /locus_tag="OUE31_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HCU0222437.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            18638..19261
                     /locus_tag="OUE31_001423"
     CDS             18638..19261
                     /locus_tag="OUE31_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HCU0222438.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            19453..20574
                     /locus_tag="OUE31_001424"
     CDS             19453..20574
                     /locus_tag="OUE31_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HCU0222439.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            20581..23709
                     /locus_tag="OUE31_001425"
     CDS             20581..23709
                     /locus_tag="OUE31_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HCU0222440.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            23728..26922
                     /locus_tag="OUE31_001426"
     CDS             23728..26922
                     /locus_tag="OUE31_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HCU0222441.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(27068..27775)
                     /locus_tag="OUE31_001427"
     CDS             complement(27068..27775)
                     /locus_tag="OUE31_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCU0222442.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            28540..28938
                     /gene="spxA"
                     /locus_tag="OUE31_001428"
     CDS             28540..28938
                     /gene="spxA"
                     /locus_tag="OUE31_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCU0222443.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            29270..29923
                     /locus_tag="OUE31_001429"
     CDS             29270..29923
                     /locus_tag="OUE31_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HCU0222444.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            30149..31147
                     /locus_tag="OUE31_001430"
     CDS             30149..31147
                     /locus_tag="OUE31_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HCU0222445.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            31323..33131
                     /gene="pepF"
                     /locus_tag="OUE31_001431"
     CDS             31323..33131
                     /gene="pepF"
                     /locus_tag="OUE31_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HCU0222446.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        11144 a         5781 c         7014 g         9271 t
ORIGIN      
        1 taagctttgg tgtggtcttt agctggcaat tggttttcta aatcagttcg gacaacaagc
       61 acatcgcaag ctgcgtttct aataacatat tcagaaacag aaccaataaa taaacgttct
      121 acagcattca atcctgtggc tcctaacata atcaaatcta cttgattatc ttctgggatt
      181 tctctggcaa taatttgttt tggtgagcca tattctacga cagaggttac attattcaag
      241 ccagctttct tcgcattgct ttcataatct gccaatgttt gctttgccat ttcagtagct
      301 tgttctgcaa gcattccatc aaaggatgaa acggtttgga aagaacgtgt gtcaatgaca
      361 tgtgctaata gaagttctcc gttatttcgg atagctacat tgaccgcctt tttaaaagct
      421 aattcagctt catcagaacc atctacggca accatgattt ttttgtattg ttgtaacata
      481 agcattcact cctcaagtca atcgtattgt actcttttat tgtagaacac tttagggaaa
      541 aagagaatta tttactgctt tggttcagca attttttttg caaatcggat actgaaggtg
      601 gcagaaacaa taattacgat cagtaaaaag accaaggcaa taaagcgttg attgaaaaaa
      661 gctgttaaaa tacccattac gcctaaaaca gcatatgcag ctccgtaaaa ttgtaggaat
      721 ccttgatttt tatcattttt gttgatcaat acaaaaaaga tatcctgttt attaaataaa
      781 taatagctaa cgaataataa tactaaagtg gcgataatca ttaaaatcct aatcatgaac
      841 aaatcctcca aaataagcaa caaatagaaa aagcaatttg ccaagagcaa attgctttat
      901 tctttaaaag atggtaatct ccgttaatgc cgttgtttgt cctgtagtat tgatcccgcg
      961 aattcaagca ggtgggtccc atggtcgtag cttcgaacta ccaaatgata aggcatgtta
     1021 ccagcagtga cacaagacgg gtcccaagat atcaataaaa atgttcggtc aacacacaaa
     1081 gaggacaatt cgaacatcac agatttccca cctctatagt agcatatgaa tttaaaaaga
     1141 gcaatgagag agctcgcaga aacagaaccg ttttcttgtc tagttttttg gaggatgctt
     1201 tttccactct tttatacggt aatactgttg acccagagcc tgttcatatt tccctgtatc
     1261 ttttggctga taatactgag cattcttcag tttatctggt aaatattgct gattgaccca
     1321 agcctgatca aaatgatgag gatactgata acccacgcca cggttgagtg atttcgcacc
     1381 tttgtaatgg ctatctctca aatgatcagg aacatctcca gctttgccct ctcgaatatc
     1441 agcaagtgct gcatctaatg ccatgtaggc agaattggat tttggcgaca agcaaagatc
     1501 gacgacgacg tctgctagtg ggatacgtgc ctcaggcaat cccaattttt cagcagctaa
     1561 tacagcgttc actgtacgag ccgcagcagc aggattacct aaacctatat cttcataacc
     1621 gataaccatc agacgccggc aaatacttgc cagatcacct gcctcaacta aacgggcgag
     1681 ataatgaagt gcagcatcca catcacttcc acgaatcgat ttttgaaaag ccgaaataac
     1741 gtcataatga gcatctccat ttttgtcatg ggtaagagct tttctttgga cacattcttc
     1801 aatgatcgac agtgtaagat gaatccttcc ttctttatct gaaggagtcg atagtgtagc
     1861 cagttccagc ccattcaatg cactccgcaa atcgccgttc gttgcacgcg aaaggtgaag
     1921 aagagcatct tcgtctaact ggattgcttg ttgtccaagg ccgcgttctt tatcccttaa
     1981 agcatgttcg actgccaact ggatgtcttg ttctgttaat ggtttgactt caaagatctg
     2041 tgtacggctg cggatcgctg gattgatggt aatataagga ttctcagtag tcgctccgat
     2101 caagatgatt cggccacttt ctaaatgagg aagcagaaaa tcctgttttg ttttatctaa
     2161 tcggtgtact tcatccaata agaggatcac tgtaccactc atttttgctt cttccgctac
     2221 aacttgtaga tccttttttg aatctgtagc ggcgtttagc atgcgaaatg cataattagt
     2281 agagccggcg atcgcacttg cgatactcgt ttttccagta ccaggaggtc catatagaat
     2341 catggaagag agcatgcgag catcgaccat gcggcgtatg atttttcctt ccccgactag
     2401 atgctgctga ccaacgactt catcgatcgt tcgaggtctc atgcgataag ccaatggctg
     2461 ttgcatagga ttttcctcct tcttgttttt acgtccctta attatatcat atttagcaag
     2521 atgcctagaa agaacagcct tctgttgttt tgttttcata gcttatccaa ctaatattgt
     2581 gtatgataaa gtaggtgaga aaaatgacgg ataaacaaaa gatagatgaa tttttttgga
     2641 ataaaacgac gccagaagtg gcacgggatt tattggggat gtatttggag catgacacac
     2701 cagaaggaag attagctgga tatattgtag acgcggaagc atacctaggt ccagaagacg
     2761 aggccgccca tagctatggt ttaagaagaa caccgcgtgt gcgggcaatg tatgaaaaac
     2821 caggtacgat ctacctttac acgatgcata ctcatcggat tttgaacatc attactcagc
     2881 cagaagggat tcctcaagga gtaatgatac gtgcaatcga acccgccgca atgattgatc
     2941 aaatgagtaa aaatcgtggc ggaaaaactg gtccagatat cagcaacggt ccgggaaaat
     3001 tagtggaagc attagcaatt cctcaagaac tttatggtca gtctatagca gatagttcgt
     3061 tacgcttagt ttttgagaaa aaaaagacac caaaaaagat caatgctttg cctagaatcg
     3121 gtatcccaaa caaaggtgta tggacagaaa agccgttgcg ttttgttgtg tcgggaaatc
     3181 cttatatctc tttacaaaga aaaaaccaaa tcgagaaaga ttggggttgg aggaaagaaa
     3241 atgaaaaaga aggatctatt aacatattta gatgaaataa ttgaaaaaca agtgacagac
     3301 tatgatgtag ctttagattg ggatacaaaa aatcatacga tcgagatcgt tgttcgcttg
     3361 tttgcagaaa ataaagcaca atttgagatt gatgatgcag aagggatcgt ttcgcaagaa
     3421 ccaattatcg aatttgaaga cggcgtactt ctttttaatc ctcagaaatc tgtttttgat
     3481 gaacgcaatt atctagcagt aatcccttat gaaggaaaaa aagggttggc aaaatcagta
     3541 gctgattctt tagtggaata tctaaatgaa gtattagctc aagggcaaag cgatttgctt
     3601 gattttttgg atgaagacga tgacgaagct gtattcgagc ttcactggga taatcagcaa
     3661 ctagcagaat tagtagaagt aaaacagcaa aatgaagcag atacttattt accgtaccca
     3721 agttattaag gagtgacaga tatgaaatgg aatgaagtaa aagtagaaac tgaaagtgaa
     3781 gcagtcgaag cagttgctaa tattttgatg gaggcagggg cgagtggtgt cgcgattgaa
     3841 gattctttag atgttgaaca ttttcagtcg gatcaatatg gtgagatttt agataaaaat
     3901 gattttacat cgctgaaaga aggcgcacta gtcatggctt attttccgga aacgactttc
     3961 ttaccggaaa tcttgccttt tatcaaagat cgtatcacac aattacctga gtttggtcta
     4021 gctattggaa aaaataaagt aacagttagt gaagtagagg aaagcaactg ggcaacagcc
     4081 tggaagaaat actatcatcc ggtgcgtatt acgcgaatgc tgacggttgc gccaagctgg
     4141 gaaaactacc agacagaaga tcctctagaa aaaattatca cactagatcc tggtatggca
     4201 tttggcacag gcactcatcc cacgacttcc ttgacattga cagcactaga aacagtcttg
     4261 cgtggtggtg aaacattgct agatgtggga actgggtcgg gcgtgctaag tattgcagca
     4321 aaatatcttg gtgcaaaaga tgtctatgcc tttgatttag acgaagtagc cgttcgttcg
     4381 gcgaaagaaa atatggatat gaatgaaata gccaaagatg tccatgtatc agctaacgat
     4441 cttttgacag gaatcgagat tgaaagtgat gtaatcgttg cgaacatttt agcagatatc
     4501 atcttattga tgatcccaga tgcttggcgt ttactgaagc aaacaggcac gctgatcgtt
     4561 tcaggaatca ttgaagagaa gaagcaaatg gttctggatg ccatgttaga acaagggttt
     4621 atcgtggatc aaattttcca gcaaaaagac tggtatgcaa ttattttgaa aaaaccagag
     4681 gtggaataga tgcagcggta ttttttaaaa gaatcatatg aatcaaaaga ctattttgtt
     4741 ttagaagggg aaaactatca ccacattgta cgggttatga ggatggaacc cgaggatgaa
     4801 gtttttttgg cattcaatga tcaaatagcc attgttgcag aaatcacgga gattactgaa
     4861 gaggctgttt atctgaaaga aattaaaaaa gaagaaaatc aaaaggaact gccaagttcg
     4921 attaccatag cgagtggcta tcctaaaggg gaaaagctgg attggatcgt tcagaaatcc
     4981 actgaattag gagcgcaagc ttttcttggt ttcccggcat cagcctctgt cgttaaatgg
     5041 gatgcaaaaa aacgtatgaa acgacaacaa cggcttgaaa agattgctca agaggcagcg
     5101 gaacaatccc atcggcagat cgtgccatca gtagagttat tggaaacgaa acaagattta
     5161 tttgagcggc tagatgatta tgacgtggtc ttggttgctt atgaggaatc agcaaagcaa
     5221 ggcgaaaaat caaatgcagc caaaattctt agtgaaacaa aaccagatag tcgaatctta
     5281 gctgtctttg gaccagaagg tggattatcc cgcgatgaag tcgattattt tgtagaacac
     5341 aaagggatac tttgtggatt aggaccaaga atccttcgta cagaaacagc acctctttat
     5401 ttattaagtg ctgctagcta tcaatgggaa ttaatgaatc cttctttcag ctaacgttct
     5461 tcattaataa aagagtatcg acagaaagaa ttgaaaaaat agtcaacaat ttgtataata
     5521 gaaacaatta tttatacaat ggatacgaaa aatcgtttga aaaagctttt aaaaagcgaa
     5581 catttccgta aaaaaacgta taactgcacg gattttggga caattatcaa acagatattt
     5641 gtcccgattc ccgttttacc gaaaaaagaa agggggatcg attcctgtga caaaagaaga
     5701 aattttaacg ggacccggtg tcataaagct cgttagtcaa tacatgggtc ccgaacatgt
     5761 agcatttgtt gagaaagcat gcgaatacgc gactgctgca catgacggac agtttagaaa
     5821 atcaggcgaa ccctacatta ttcatcctat ccaagtcgca ggtatattag cagatttaaa
     5881 aatggatccc catacagtgg ctacaggctt cttacatgat gttgttgaag atacagaaat
     5941 cactttagaa gatctgagag aagaatttgg cgatgacgtt gctatgttag tggacggcgt
     6001 aaccaaatta gggaaaataa aatataaatc ccacgaagag cagctagcag aaaaccaccg
     6061 aaagatgctg ctagcaatgg ctcaagattt acgagttatc atggtcaaat tagctgatag
     6121 actacataac atgcgtacgt tgaagcacct gcgagaagat aagcaaagaa ggatcgctca
     6181 ggaaacttta gaaatctatg cgcctcttgc acatcgtcta gggatcagcc ggatcaaatg
     6241 ggaattagaa gatacagcac ttcgttatct aaatccaaaa cagtattacc gtatcgtcca
     6301 cttgatgcag acgaagagag aagaacgtga aaaatacgta agtggtactg ttgaagatat
     6361 tcgaatagcg acagaagagc tggggatttt tgcagaaatc tatggacggc caaaacacat
     6421 ttattcaatc tatcgtaaaa tgaaagatca gaaaaagcag ttcaacgaaa tttatgactt
     6481 gctagctatt cgagtgatcg tagattcaat caaggattgt tatgctgtat taggagcaat
     6541 ccacacaaaa tggaaaccaa tgcccggcag atttaaggat tatattgcca tgccaaaagc
     6601 taatatgtac caatctttgc atactaccgt gatcggtccg gcaggaaatc cggtagaaat
     6661 tcaaatccga acacaggaaa tgcatgaaat cgctgaattc ggggttgctg cacactgggc
     6721 ctataaagaa ggaaaaaatg aaaaagtaga accagatggt atgacgaaac aattaagctg
     6781 gttccatgag atactcgaac ttcaagacga aagctatgat gcttctgaat ttatggaagg
     6841 cgtaaaagga gatatcttta gtgataaagt ctacgtcttc acaccaaaag gagacgttac
     6901 tgagttacca aaaggatccg gaccattgga ctttgcatac agtatccata cagatatcgg
     6961 taacaaaacc actggtgcaa aagtaaatgg caaaatggtg cagcttgatt acaaattgaa
     7021 aaacggagat atcattgaga tcatgacttc tccaaattca tttggcccaa gtcgcgactg
     7081 gttgaaatta gttgctacta gcaaagcaag aaataagatc aaacgtttct tcaaagccca
     7141 agatcgagaa gaaaatgtga tcaaaggcca cgaatccgtg gtcaaatgta ttacagatct
     7201 aggatttacg cctaaagata ttttgacgaa gaacaaactg caagaagcac tcgatcgttt
     7261 taattatcaa acagaagatg atctctatgc agctgtaggg tatggagaag ttagcccctt
     7321 gacgatggcc aatcgtctga ctgaaaaaga acgtaaagaa caaaaaatcg agcagcaaaa
     7381 gcaagaagca gaagaaatca tgaatcagcc gaaaaaagaa cctgacaaaa tgaaagtacg
     7441 tcatgaaggt ggcgttgtca ttcaaggggt agaaaactta ctaattcgta tcagtcgctg
     7501 ctgtaatccg attcctggtg atgatatcgt tggttatatc actaaaggca gagggatatc
     7561 cattcatcgt cgagattgtc cgaatgttca gcctgacaaa ccaaatgtag cagaacgttt
     7621 gattgaagtc gaatgggaag atacatcgaa tacacgaaaa gagtatgatg cagatttgga
     7681 aatttacggc tataatcgtt caggcttatt gaatgatgta cttcaaacag tcaatgcgct
     7741 aacgaaaaat ctcaacagcg ttgaagcacg gacgaataaa gataaaatgg cgacgatcca
     7801 tttgacggtt ggtatccaga atttatccca cctaaagagt atcgtggata aaatcaaagc
     7861 agtacctgat gtctacagtg tacgccggac gaatggatag gaggacagat atgagagcag
     7921 ttgttcaacg ggtaagtaaa gctgctgtgt cagtcgatca gcaagaaatt ggaaaaattg
     7981 gctacggcct acttgtttta ttaggcattc atgaaaccga tacgcaaaaa gatgtggact
     8041 atctggtaaa aaaaattgca caaatgcgta tttttgaaga tgaacaagga aaaatgaata
     8101 ttagtgtaga agatgtggga ggacaaattt taagtatctc tcaattcaca ctgtttgcgg
     8161 atacgaaaaa aggaaatcga ccaagctttg tggaagccgc acgaccagaa acagctattc
     8221 ctttatacga atcattcaat gaaggaatca gaagtcgcgg catcacagtc gctaccggac
     8281 aattcggagc agatatgtcg gtttctctcg tcaatgatgg acctgtaacg atcattattg
     8341 attctaaaaa caaataaagt aatctggttt tcactagtaa aaactatgaa acacgtcgct
     8401 taagttagac tgataaactc taacttaagt ggcttttttg tctgcaaaaa gcgcttcttt
     8461 tgtcagcagt cggaaaaaaa gttaagctta aattatacaa gttatttttt ataggaggtt
     8521 gctgaagatg aaagaagtac cagtagtaga tatcaaaatc acagatttaa aaaaattgta
     8581 tcaaaaagga tacaacatgt tggaggagtt acgccatgaa gcggacgctc ccgtcgtcaa
     8641 agcaaagatt ttcaataaag aagctatcac gatctacgga tcatcagcag caaaagtatt
     8701 ttatgatcca aggaatttca aacgaaaagg tgctatgcca aaattagtat tgaagacact
     8761 ttttggtcaa ggtggagtac agactttgga tggagctgct catcaccatc ggaaaaatat
     8821 ttttatggat ctaatgacac cggaaagaat ggaagattat catcgtatct tagataagaa
     8881 tctgacacaa gcacttgaag cacagcatgg tcaatttgaa ctatttgatt taagtaagat
     8941 ggttttcttt acatctattt gcgagtgggc aggtatcaat ttatcagcga tttctaaaga
     9001 tgaggtcgaa aaattagcag aatatcaaat ctctatgatc agcggaacgt ttacttctcc
     9061 gattgatcac ataaaaggtg tcgaaaatcg caaaaaatca gaaaaatggg cgcaaggctt
     9121 gattgaagaa gctcgacaaa atcctgtggc tggaaaagaa aatgtggcat tatatgcttt
     9181 tgccaatgcc acagatttag atggtcagct tttacctctg gaagtggcag ctgttgaatt
     9241 attgaacatc atccgtccaa cggttgctct aactgtgtgg gcggcattga tgggacatgc
     9301 acttttcagt agaccagatt tgtatcagca attaaaaaat gacttttcga cgttacaaga
     9361 tccgtttatt caagaaatga gacgctatta tcctttcttc ccaatgctac ctgcgatttc
     9421 gctgaaagaa gtagaagtag atggttatcg tataccagaa ggcagttggg ttattttaga
     9481 tttatatgga acagaccatg atgaacgaac agttgaagcg ccagattcct ttatgatcaa
     9541 acggtatgta gggaaagcaa aagatatttc ctataaagaa gaatatgaga tgattgcaca
     9601 aggcggggga aattttcgac aaatgcatcg ctgtgcagga gaatggatca ctcttcatag
     9661 tctacgtgtg ttttccgatc agctagtaaa taagtttgag ttctctgtac ctgaacaaga
     9721 ttggacgatt ccattcaatc agtttccgac ttatccgaat agccgagcgc tactttacaa
     9781 gaattagatt agcataaact tatcgaaaaa aaggaagatc aaacagtgct gatcttcctt
     9841 ttttcatatt actataaatt gataaggtca attgatcaaa atccacgaaa tgcttcatca
     9901 atggtttgat aatcttcatt ggataaatgc aaatctaaag cttggacatt gtcagatact
     9961 tgctctggac gcttagctcc aggtataact acagacactc gtggattctt catgtaccaa
    10021 gctaaaacaa gttgcgcagg agtggcttgg tatcttttag caatggggcg aagtacatcg
    10081 acagcggtta aaatttctct gaaacgttct ccttggaaat ctggatttct ttttcgagga
    10141 tctccttcac caaattgttt ttcctcacca agttcatatt ttcctgtcag caaaccggaa
    10201 gcaagaggaa aatagggaac aaaactgatt ttgttttttt caagataagg gaataattct
    10261 ttttcagcct gccgatggat caaactgtat ttatcttcta ctacatcgac atatccatct
    10321 gcattcgctt ctttcaattg ttctaacgtg aagtttgaca caccgactgc tcggattttt
    10381 cctgcttctt ttaattcgtg caatgtagca actgattcat tttttggtgt gctttcatcc
    10441 ggaaagtgga tataaaaaat gtcgatgtaa tcagtttgca gacgttttag tgcatcttcc
    10501 accgattgtt tgagaaactc aggagaatta tcaaatgttc gccctttatt tggtacatga
    10561 gcagcttttg tagcgatgac gacacgtgag cgatcatatt ctttttcctt cagtacctcg
    10621 ccaatcagtt cttcggaacg gccgtttccg taagcataag cggtatcgat caaattgatc
    10681 ccgctattca aagctgtacg aactacttgt tttcctgtct catcttccaa accgtcaaaa
    10741 agattatgtc ctccaacggc atttgctcct aatccaagct gttctgcgta gacttgtgaa
    10801 tgtccgattc ttatttctgc catagctgat tcctcctttt tgtctagtct aaaacaaaat
    10861 accaaaaagc tgaactaaaa cgtttttgtg aggggaaata gtcagatatc tcttgacttt
    10921 gagactggtt tttagtaggt tataagtaat atcgaatgtc aatgaaagag cgagtaagtt
    10981 tttgaaactt tacaagagag gatcatcgag gctgaaaatg atctaaagtt tcattagcct
    11041 aaagacactc tggagatgga cgagtgaaaa gccgtcccgc gtacgagcgt tattcgtaag
    11101 aggaaagaga aatctttcaa aattaggtgg taccgtgtat gaatttcatt cacccttgtt
    11161 catgatgaac aagggtgatt tttttattta catagctaag aaagggagag aaaactatga
    11221 gtttccaaag accaaaagga acaaatgata ttttgccagg cgaatcagaa aaatggcagt
    11281 ttgtcgaaga aacagcacgt ttattattca gagattatca gtataatgaa atgcgtacac
    11341 cgatttttga acactatgaa gtgatatccc gaagtgtagg ggatacaacg gatatcgttt
    11401 caaaagagat gtatgatttt tatgacaaag gggaacgcca tgtgacgctt cgaccagaag
    11461 gtacagcacc aatcgttcgt tcttttgttg agcataaatt gttcggccca gagtatgcga
    11521 aaccgttcaa aactttttat atgggaccaa tgtttcgcta cgaacgccct caaaaaggac
    11581 ggttacgtca attccatcaa atcggagtag aagcatttgg atcagaaaac cctgcaactg
    11641 atgtggagag catggtgatg gcacttgatt tcttcaaaca gttggggatc acgcaaatcc
    11701 ggctagtcat caattcatta ggtgataaag aaacgcgtca agcctatcgt caagcattga
    11761 tcgactatct tttacctttt gaatcagagc tgagtgaaga ctctaaacgc cgccttcatg
    11821 aaaatccatt acgcgtattg gacagtaaag acaaacgaga tcaaaaattt gtggcagaag
    11881 ctccatctat cttagattat ctaagcgagc ctgctcaaaa acattttgat accgttgttt
    11941 ccatgctgga tgcattggct gttccttatg aaatcgacag taatatggtt cgcggactag
    12001 attattacac acatacgatt tttgaaatca tgagtgacgc accaaaaatg ggggcacaag
    12061 caacgatttg cgcaggcgga cgttatgaca atctagtgga agaactaggt ggtccttcaa
    12121 cacctggctt cggatttgca atgggtatcg agcgattact cttgactatg gaggcagagg
    12181 aagtagttat ccctgcattt aatgagttgg atgcttacgt ggtcgcactc ggagacgaaa
    12241 caaatatcga agcattgaaa gtggtccaag cgattcgaaa ctttggtttt tcagctgacc
    12301 gcgacttcat gaaccgtaaa gcaaaagcgc aatttaagac agcagataaa gcgaatgcca
    12361 aattagtatt ggtgatcggt gaagatgagc ttgctagtca aacgattaat gtcaaagcaa
    12421 tggcaagccg aaaagaaaaa agttttccat tagaagagat atatgaacat tttgatgaag
    12481 tctatgatga aatgacttta ttcgagtagg aggaaaaaaa taaatggcac aaagaacgat
    12541 ctattgcgga ttagtttccg aacaacaatt agaacaaaca gttacattaa aaggatgggt
    12601 acaaaaaaga cgagaccttg ggggagtaat ctttatcgac ctacgtgatc gtgaaggaat
    12661 cgttcaaatc gtctttaatc ctgaaatcaa caaagaagca tgggaaatcg cggataaatg
    12721 tcgcagtgaa tacgtgatcg aagtgactgg ggaagttaga agacgcggag aaaatgcagt
    12781 aaatcctaaa atggccactg gtgaattcga agtgattgca agtgaaatcg tgattttgaa
    12841 tcaagcaaaa accccgccat ttcaaattga agatgatcaa gcaatcagtg acgaaatacg
    12901 tttgaaatat cgttatttgg atctgcgtcg tccaaaaatg actaaaaaca tcaaattaag
    12961 aaatgcgaca acaaaagcga ttcgtcatta tttagatgat aatgactttc tcgatatcga
    13021 aacaccttac ctagggaaat ctacaccaga aggcgcaaga gactacctag ttccttcacg
    13081 tgtccatgct ggacatttct atgcgttgcc gcaatctcct caattgttta aacaattgct
    13141 gatgaatgct ggattcgacc gttattatca aatcgttcgt tgtttccgcg atgaagattt
    13201 acgtggagac cgtcagcctg aatttacgca agtagatatt gaaacaacgt tcttaacagc
    13261 agaagaaatc caaacttaca cagagggatt gattgcgaag gtaatgaaag aagttcgcgg
    13321 tatcgaagtc acattgccat ttcctcgtat gacctatgat gaagcaatgg ctcgctacgg
    13381 cagcgacaaa ccggatacac gttttgatat ggaattgatc gatctaagcg atacagtcaa
    13441 agaagtagaa ttcaaagtct tccaaatggc tcttgaaaac ggcggtgtcg tgaaagcatt
    13501 gaatgctaaa ggcgctgcag atcgctactc acgaaaagac atggatcagt taggtcaata
    13561 tgtaggacaa ttcggagcta aggggcttgc atggctgaaa gtagaagaag acggattgaa
    13621 aggtccaatt gctaaattca tgggagaagc aacagaagca atcattaaag caacagatgc
    13681 aaaaccaggt gacttgctga tgtttggcgc agataaaagt gaaatcgtcg ctgctgcatt
    13741 aggtgctatc cggacacgtt taggaaaaga attaggacta attgatgaat cgaaattcaa
    13801 tttcttatgg gtaactgatt ggccacaatt tgaattttca gaagaagaag gtcgatatgt
    13861 ctctgctcac catccattca cgatgccaaa agaagaagat atcccgttat tggctgaaga
    13921 ccctgcaaaa gtctatgcag aagcttatga tatcgtcttg aacggttatg aactaggcgg
    13981 aggttctatc cgtattcata ctcgtgagct tcaagaaaaa gtactagaaa ctctaggctt
    14041 tacaaaagaa caaatggaag aacaatttgg tttcttgtta acagctttag attacggatt
    14101 ccctccacat ggcggtattg cattaggatt ggaccgtttt gcaatgttat tagccggaga
    14161 agataatatt cgtgaagtca ttgcctttcc taaaaacgga aaagcagcag atgtgatgag
    14221 tgatgcacca agtatggttt cgcctttaca attgttcgaa ttgaatattg atgtaacgaa
    14281 tatagaagaa tagccgataa aaaggtaaaa aggatttgtc gaatacgctt cttttgacaa
    14341 ccttgattta attgaaaaac actttataat gaagccataa catataaagc ggggcttttc
    14401 catgaaaaaa acattcgaaa attgggctta tcatgattac acgaccaagc tttcggtatc
    14461 tatcgtttat gcgttgatcg catcagtcgc attgaatttc ttttatcagc caggacatat
    14521 ttattcaagt ggtattactg gtctagctca gattttgacg actttgtcaa aatcactgat
    14581 aggattcgaa gtaccggtat caacaacttt gtatttactg aatatacctt tgtttgtatt
    14641 ggcgtggtta aaaatcggga agaagtttac aattttcact tttatcacag tcactttgac
    14701 ctccctttgt atccatattt taccggaaac agtcctatct accgatccaa tcatctgtgc
    14761 gttgtttggg ggggctgtga tgggactagg tattgggcta gcgttgagaa acggcctatc
    14821 atcgggcggt ctagatatcg tgagtatcac gattcgtaaa aaaacaggaa agtcgattgg
    14881 ttctatttcg atctacttca atgcattgat cgtttttgtt gccggaattc tatttggctg
    14941 gcaatatatg ttttacagta cgttgtctat tttcgtcagt ggaaaagtaa ctgatgtcgt
    15001 ttatactaaa caaaagaaga tgcaggtaat gatcgtaacg aaacatccag aaaaagtagt
    15061 aaatgaaatc caaaactgta tgcgtagagg gatcacgatc atcaatgaag cagaaggtgc
    15121 ttataagcat gataagcaga cagtattgat gacgatcgtt acacgatacg aactgcctct
    15181 acttagagaa gcaatgaaag cttctgatcc acaagctttt gtaagtattg cagaaaacgt
    15241 ccagatactt ggtcgtttct atgaggatgg catttagatc gagtttgaca aaaattcatg
    15301 aaatactgct gtagacagac gttcgtttgt ctgcagtttt tttctaccat agtagaatca
    15361 gcaaagaaaa actgcttttt tatttgaaat tttcttaaag ttgaaaaaaa gcatgtttat
    15421 ttttttaaat ttatgggatg atagaaaaaa atagtagaga aaggacacga ttctacttgc
    15481 tattttcact taatacccgt atattacgaa tgaaaaaagt ttatgaaaag ttggaatatt
    15541 gaatggaaaa acaaaaaagg ttaaaaaaca gccgctacat cactgggttt gatgggctcc
    15601 gttcattagc tgtggtgggt gttatcttct atcaccttct gccaactagt atgaaaggcg
    15661 gctatttggg cgttccgatt tttttcgtcg tatctggtta tttgatcacg gatctgctgc
    15721 ggcaggaatg ggaacaaaat ggaaaaatca atatttggca attttatgtc agaagaatga
    15781 agagactcta tccggcactt gtttttatgc ttgtgacagc ttcggcttat atcactttgt
    15841 ttcagcgagg gctgttaaac aatcttcgag gagttgtggt cagcagctta ctgtatgtca
    15901 acaactggtg gcaaatcaat aacggtttat cttatttcga tcgatttgct aatgagtcac
    15961 cgtttacgca tatctggtct ttagcagtag aaggtcaaaa ctatttggtt tggccgatct
    16021 tgtttgtatt gttgatggta tttgttcgta aaagaaaatg gatcttttat actgtgttag
    16081 gtacatcctt cctctccgcc atcttgatga tgatcttgta tacaccagga ggcgatccaa
    16141 cccgtgttta ttacggtacc gacactcgtc tgttttctat atggttggga agtgcgcttg
    16201 cgtttgtttg gccaagtacg cgtttaaaga aaaacatccc gaaacaagcg aaaaatattc
    16261 tgaatatcgc tggaggaatc tcgcttttgg cactgattct ttgcttcttc tttttagatg
    16321 atcattacaa tttcatctat tacggaggaa tgctcctagt gagtctgtta tgcgtagtgc
    16381 tagttgcagt gacagcacac cccggagcaa gtttgaatcg atggctgaca aatccagtat
    16441 ttacttggat tggcaaacga agctatggca tttatctgta tcagtttcca gttatgattt
    16501 tttatgaagc aaaggtgact gatattgccg atcatgtttt gttgcatact ttagtggaaa
    16561 tcacattgat tctaatcatc agtgaacttt cttatcgata tgtggagcgt ccgctagcac
    16621 gttttgatta tggtcgtaca ttccaagtga tgaaaggatg gttcagcaaa ccgatcatca
    16681 gtaagagcaa accatgggtt gttccaggca cattacttgt agcaattgca ctcgttggtt
    16741 tcgttacggc accgaaaaac gctgtaacag ccgatcaaaa acaactgcag gcaaaaatcg
    16801 ctgaaagtaa aaaattagca gaagaaacca gaaacaattc agaaaacacc actagttcgg
    16861 ttgaccaagc gatccttgat aagtacgagt tgtccaaggc acaagggaat aaggcacaaa
    16921 aattagaact aacggcattt ggtgattcag ttatgttgga tgctgcaacg gatctacaag
    16981 aactttatcc aaaagtagtg gtagatggag atgtcggacg acaattatat gccagtgtac
    17041 cgtacattga aaaattaaag gaacaagatt tgttgaaaga cactgttctg atcggactag
    17101 gaacgaatgg ctcattctcg gaagctcagt ttgatagtgt gatggatgca atcggtgatc
    17161 gaaaagtata ctgggtcaat gtccgagtac cgacgaagcg ctggcaaaat gacgtgaatg
    17221 cgatgcttga acagatgacg aaaaaatacg acaatatgac gctgattgat tggtacagct
    17281 acagtaatga ccatagtgac tggttttatg atgatcaagt ccatccaaat cctgaaggga
    17341 tgacacatta cattcactta gtcagcgaag ccttgctagg aggaagttca agtacgaaca
    17401 gcagtgagac aaacgtgaca gaatgatagc tacaaaaaac ttcaggcaaa aacatttgtt
    17461 tttgcctgaa gtttttttat atttaccgtg tttttaacat tcatatagat tcaggaagca
    17521 aaacggttga gtgtgtctgt aaataacgtt ctttttgttt tcgggtgagt tttttgaatg
    17581 cagcttctgc ttttgttgct tcgcttcttg aagaaaatac ttctgcatgg atcatcttaa
    17641 caggtcttct tttttgaaga cgagtatatt tagcaccagt accattgtta tgttcctcta
    17701 atcgtctaga aagatcggtt gtatatccac cataaaatgt ctgatcttta cagaataata
    17761 cgtaaaaata atgttcattt gccatagagc atctcacgaa tctctgcagt gtattctcca
    17821 tccatattgt aagtgatcaa tggtggagcg actttgaatc cgtctaattt gccttctttg
    17881 attccttcaa ctaacaaaat atttgcctct tttccaggtt ttgggtaaac aaattggatc
    17941 cttttaggtg caattcgata gtcttccatg acctgaatga tttctaagaa ccgatcagga
    18001 cgatggacca tagtaaagcg tccatttgtt tttagtagct tacttgaaat atcgatcact
    18061 tcttctaacg tcgtatgaat ctcatgacgg gcgattgcca ggtgtttatt agggttcgtt
    18121 ttatttgttg gcagcccttt gaaataaggt ggattacaga cgactaagtc acaagaatta
    18181 tgtcgaacga cagataagct gtctttcaga tcgatggtgt ggacagtcat ttgttcattt
    18241 aaatggttaa gcgcgatact acgtcttgcc atgtctgcta gacgaggttg aagttcgata
    18301 gcgtcgatag ccgcctgggt tcgtttactt aaaaaaagtc caactgcgcc atttcctgca
    18361 caaaggtcaa caatcttccc ttttttaggt acacgggaaa agtgagcaag cagcacagca
    18421 tctaaagaaa aagaaaacac tttggaactt tggataatct tgatatcttc tgcgtataat
    18481 tggtcgattc gttcgtcttc gtgaagcatg gattccctcc aaaatgaaaa aaatagtcgt
    18541 ctgtattata ctatttttat taaaaagaac caaggtggct tgtcaaacct ctatttttta
    18601 tgcatactat gaccataaga agggaaagga agagactatg ttttatcgat ttatgcgcgg
    18661 ggtagttcga gtactattag ccttagttaa tggaaatgcc cgctatgaga ataaagaagt
    18721 tttaccgcaa gatgagaatt acatactagt tgctccccat cgtacttggt gggacccatt
    18781 atatctggcg gtagctgcag cacccaagga attcagcttt atggcaaaag aagaactgtt
    18841 caaaaatcca gttctgcgat ttatattaac tcgatccaat gcttttccag ttaaaagaga
    18901 aaatccagga ccaagcgtca ttaaaacacc tgtaaagatt ttgaaatcga caaatttgag
    18961 tttgatcatg tttcccagtg ggacaagaca tgctacagaa cttaaaggcg gaatggcatt
    19021 gatttccaga atgtctaaag cgaaaatcgt gccagctgta tatcaaggtc cgttgacact
    19081 tggggatctg ttcaagcgtc agagagtgac agtgcgtttc ggcgaaccaa tcgacttatc
    19141 agatatcaag aaaacggata aagaaggtat ggcggagatc gaacgacgaa cacaagcagc
    19201 ttttgacaaa ttggacaaag aagtgaaccc tgatttcaaa tatgaagtca aaaaaaaata
    19261 aaatgataag tttatgcgtg ggcggtcttt tgaatctact gtcctgttca gttcagactt
    19321 tttcaatgaa aacgagggag agacgtcaag tctgccctct ttttgcgttc caatatgtaa
    19381 aatagaagac aggtgtcatg taatggatca aagtgttata ataattagaa ggacattttt
    19441 tgaggtgatt gaatgcgttt tttacataca gccgattggc atatcggaaa aaaactacaa
    19501 ggttatgact tgattgaaga ccagcgtcat gtactatctt ctatactaga tatcgcgaaa
    19561 gaagaaaaag tagaggcaat cgtgattgcc ggagacttat atgataggag tgtcccagct
    19621 gttgatgccg tagaattata caatgaattg atggtcgatt ggaatttaaa ggaaaagatc
    19681 ccgatttttg ctatatcagg aaatcacgat agcagtacga gactttcagc gggtacgcca
    19741 tggttcagtt attcgaacta ttttttgcga acacagctag cagaagcatt tgaaccagtc
    19801 gagtttaaaa acgtacaatt tttctttctt ccttactttg aaccaattgc agcgagatta
    19861 tattttgaag atgacaatat ccgaacgatc aagcaagcgg tagccaaggt gatagataaa
    19921 atgcaggagc tatttgattc agaaaaaaaa caagtattga ttagccattt ttttgtaatg
    19981 ggaagtgtaa aatctgattc ggaaacgaaa atcgaagtag gcgggttgga ttcgatccct
    20041 ggtgaactac ttacaccgtt tgattatgta gcactaggac atttgcataa tcaagctgct
    20101 ttgagacagg ataatgctcg ctatagcggt tccccattga aattctcttt atctgagatc
    20161 aaccaaaaaa aaggcgtatg gatcgttgac ctgacaacag gcctggagtt gaattttagg
    20221 gagatcgaac ccctgcatga tattgaagaa ataacagcga gtttcaaaga attgctggat
    20281 cctgcctttt atcagtccgt caatcgggag aattacatct atatctatct cactgataga
    20341 acgatcatcc cgaatatgat gaaccagctt cggcaaatat atcctcgtat tttggggatt
    20401 gaacgggcaa acggtcgagc agaacaaaca aagcgcaaac gaaaagtact agaaatgaaa
    20461 gatcctcaaa aattagcaga agcatttttt agtgaaatga cggaagagca gctaactgca
    20521 aaccaagaaa aatggctcgg agaaacgttg caagaaatca tggaaatgga atgatcaaga
    20581 atgaaaccga aaaaattaca acttaaaaat tttggtcctt ttatcaatga gaccgtagat
    20641 ttttcacgtt tgacagaagc accgcttttt ttgatcagcg ggaagacagg agctggcaaa
    20701 acgacgattt ttgatgggat caccttcgca ctttttggtg aaacttccgg aagacttcgc
    20761 tctggaaaag agatgcgttc tttgtttgct acaccagacg aagaaacaag cgtgactttt
    20821 tcttttgaac atcagcagat gagctatgaa atcgaacgaa aaccagaaca agttttagca
    20881 aaacgaaaag gaaacggaac aaaaaaacag gcagccaaag taacgttgac catttttgat
    20941 gggaaaggaa aagaaataaa acaaatcaca aaacgtacag aagcagatca gttgatcaga
    21001 gaactgatga atctcgatgc gaaacagttt tctcaaatcg ttttactacc ccaaggagaa
    21061 ttccgtaatt ttttggtttc atcaagcagt gataaagaga ctgttttacg tcatttattc
    21121 ggtactcaat ttttccaaca gttcaatgag cgattaaaag aaaaagcaaa acaacagcaa
    21181 caaaaattgg atcatttaga gcaagagctg catcttctgc aaaaaaggtt tgttttagtc
    21241 aaagaagagg aaccagcagc agggtttgaa gccgttttag cccaatggac aaaccatcag
    21301 gcaatactcg aaaaacaaat cacggaagaa aaagaagctc taacggaact tcaggaaaaa
    21361 caaaagcaac tagaaaattc ctactatcgt tttgaaagct tgaaaaaaag ttatgaagaa
    21421 aaaacgatat taataaacaa gcaaaaggaa ttagctgctc aaaaagacga aatagaggaa
    21481 aagaaacgat ggattgggta ttatgaattt acgcaacgat tagtcgaacc aatccagcgc
    21541 ctacaagaaa taaaagttga aaaaatagaa ctgtcacaaa aaagtagtga gcaaacaaag
    21601 aaactagcga tgactacgca gaattatgaa gagtggcaaa aaaatgaagc aaaccgcgta
    21661 cgccgacaaa caaaaatcaa agaagctgct caaaaactgc aaaacaaaca gatgatggtg
    21721 ccaattgtcg aatccttacg tagtaaaaaa caagacgcag aacaattaac aatttcattg
    21781 gataaagaag aattgaatgc cgagaagctg tatcaaaatc tcgctatcta tcaggaaaga
    21841 actcgaattc ttcaagaaaa tttactggat caggaaaaac tgcaagaaga tcgtcttgct
    21901 tttggacagt taaaatatct agatgaaaag cagcaagaaa tagaaaaaca aaaagcaaaa
    21961 gacactgggt cgctcgcaca gataagagaa gaactcaaaa aagcaactga agaaataaca
    22021 aaaaatagtc agctattgaa agaacagaca gaacaagcag aacagctgaa aagccaatgg
    22081 gcaaagcagc aaattgctcg tcttcagctt tttttgcgtc caggggagcc atgtcttgtt
    22141 tgtggatcaa cggaacaccc catacaacaa ttaaaacacg aacagccaaa taaggaagat
    22201 atcttaaaag tagaacaaca actggcagaa gctgagtctg ctgtagaaag aactcagcaa
    22261 atcattgcca aaagtgaagc acatgaaaat aatcttcaac aacaattatc agatttagaa
    22321 caaaaaatca tggcaacgaa tatacaattg gctgaacaag aagaacactt gcaacaggct
    22381 ttgaaaaagg catttcctga gataacagaa caaaaaacaa aaacaactct tgtagtaatc
    22441 gaacaatctt tagatagacg aaaaagcaag atggccaatg caagaataga gctggaagaa
    22501 ataagacaac aagcagaaaa gctcgaacaa caattagctg tctacaaaca gcagcagaca
    22561 gaaaaaaata atcagctcca gcaactgcaa ggagaaatca aaagtttaga acaacaattg
    22621 caagatacgg atagtaactg tttagaagag gagatacgac gacttgaaaa acagttagaa
    22681 gaagactcga atcaactagc tgttgagcag aaagcaggag tgcaattgtt gcaagatctt
    22741 catacgcttc ggacacagct tgatcttcaa catgaacaaa tagaaaaaat agatgaaaaa
    22801 atagaaaagg aacaagaaag aatagctaaa aagttagaaa gccagtcgta tttttcaaca
    22861 attgaagaaa tctgtgcatt tgcacaacag caagcacaat ataaagaaaa ccaacgtaca
    22921 gttacttctt atcatgaaga gcaattagtg acagctgacc ggctgcgtca attagaaaat
    22981 atccagctaa ctgagacatt cccagataca gaagagatca gccaacagtt agaagaaata
    23041 agacgtatga tcgaaataaa gcaagaaaag atatacggtt tacaagaaca aaaaattagt
    23101 aatcaaaaaa tctacgatga atgtctttcg atttatcaca caagccagac gaaattagat
    23161 gagcttacgc aattacagca gctttcgcaa acattcaacg gagaaaatcc taagaagact
    23221 agtttggaac ggtatgtgct tcaggtttat cttcaagaag tgttacaagt agcaaatgat
    23281 catctccaac gtttaacgaa aaatcgttat caatttgagc tagcggatac cattggcagt
    23341 tatcgaggga aaaccggatt agaaatcaat atctatgatg atcaggcagg tatgtctcga
    23401 agtgcgcata ccctgtctgg cggtgagagt tttattgcag cactttcttt agcattagct
    23461 cttgccgatg tgatccagac acaagctggt ggtgtagcaa tcgatgcatt gtttattgat
    23521 gaaggatttg ggtcattaga tgaagaagct ttggaaatgg caatggaagc tttagaaacg
    23581 atcgaaagtg aaggaagaat gatcggcatc attagtcatg taagagaatt gaaagaacga
    23641 gtattacaac aaataagaat tgatacagaa ggtagcggac aaagcaaaat acgctatcaa
    23701 cttggataaa aagggagatt ggtaactatg aaatggagta ttccagaaaa agtcattgca
    23761 cgtggacgtc aatacttgca agaaggccga gtgttatcgg ttgtccctga ccaagaagaa
    23821 aacgtgtggc atgcagaagt cttgggcagt gaattgtata tggttgattt ggatggtaca
    23881 gcaaaagaga tagattactg ccaatgtccc tattgggagg aacataaata ttgtaagcat
    23941 acagttgctg tggaacttta tttacggtcg aaaaatctat ctcgtatcat gaaaaaagac
    24001 cagccaatgc tagaaccggt aaaagcaaca agtgagggag aaatcattgc aaaaggtttt
    24061 tctcgtctaa aaacacaaaa caatcctcaa gcggtgcaac ctttgattat tgaataccaa
    24121 gtagaaacga ttgagactaa tcagtatcac ccagagcttt ctattttggc actttacttg
    24181 cgtatcggtt cattggcatc accgaaaaaa acatatatcg taaaaaacat ctatgatttt
    24241 ttacaagctt acacagaaaa agaaacttac actgttaata aacagtacca gtttcgtcta
    24301 gataaacggg cgtttcaaaa agaagatcaa aaaatactca cgcatcttgc aggaagtgct
    24361 cagacgcatc aattattagg tacgaacggc ttacaagtca aaggaaaact agataaaaga
    24421 tatctgcttc tcccagtaga acaagcccgc ttcctgttag agcagatgaa tcagactaca
    24481 cgtttgcatc tgcagataaa tgaacaaaac gatcaaggaa tacaattttc cgatcaaaac
    24541 aaacctttat cattcaaagt ggaaaaattt ggagaagatt atttgctgca agcattgaat
    24601 gattttgatt ttttctttat gcattatcag tggggagtta tccaagggac attttattct
    24661 ctgacgaaat atcaacaaac ggtttatcaa acttggaaac aattgattcg ccgattggag
    24721 aaaccagaag tagtgttcaa gaaaaaagaa ttaccgtctt tgtttaaaga gattatccct
    24781 ctgctgtcag agatcggcga cgtagctatt gcccctgcag tagaagagga agtagcagat
    24841 atccccgtcg aatttatttt ctttttccga aaagcaaaag gaaaaatcca agctcgagtc
    24901 gatttcgtct atggcgaagt catctattcg actgacccga agcatgaggt ctcgacagaa
    24961 caggcttttc aggtgttacg tgacacagta gaagagaaac gagtacttga tctattcaga
    25021 atgtatcgct accagaaaaa tgaaactggt tatgaacgtc cattgccaag cggggaagaa
    25081 ctatatgcct ttttccgcac agaactatct gtcttccgtc agtttggtga agtcagactt
    25141 ggaagaaaat tgcgagagtt gtatttagat gcgcataaac atcaaccgaa aatcgaagta
    25201 accgagaccg gttcatggct cgatattcga ttcgatgtga cagggataga ggagcaagaa
    25261 atcgatcatg tcctgcaaag cttgctgaga aatgatgctt tttatacatt agaaaatggt
    25321 caggttcttt cttttgattc agaagaattt caacaaacaa gccaagtgtt gcaacaatta
    25381 cgggaatcga tacgtacaga agaaggaacg atccatgtac ctaaaaatca aggattgatc
    25441 attcaaaatc aattggaaaa aagcaatgct acttttagtg aatcgttcca aacgatggta
    25501 caagatctca ttcatccaga aagataccag gcacagcttc ccaaaggatt gaatgcaacg
    25561 atgagagatt atcaaaagca aggttttcga tggttgaaga tgttaggtca ttatcagttt
    25621 ggcggtattt tagccgatga aatgggactt gggaaaacac tacagacaat tgccttttta
    25681 ctttcggaaa aagaagaacg gaaaagcttc tctgctttga tcgtagcgcc tgcgagctta
    25741 atttacaact ggcaggcaga ggtgagaaaa ttcgcccctt ctttaagtat ccaagtaatc
    25801 aatgggaata aaaaagaacg tgaagaatta ctggctaaag acacagatat ccgagtgact
    25861 tcttatgcca gcttaagaca ggatctagct aattatcagt cgcaaaaaat tgattatttg
    25921 attcttgatg aggcacaaat ggtcaaaaat agcagtacga aaactgcaca agcattgaga
    25981 gaattagctg tacctcagcg gtttgcactg agtgggacac caatcgagaa taatttagaa
    26041 gaattgtggt cattgtttgc aacgattatg ccaggatttt tcccgactaa aacaaaattc
    26101 agggaacttg ccgcagaaga aattgcgcaa atgattcgac cgtttatttt acggcgagat
    26161 aaacaaactg tgttgaaaga cttgccggaa aaaacagaga tgaatctata ttctgcactt
    26221 acagaagaac aaaaaactgt ttatttagct tacttgcgtc aaatgcgtga agaaatcaca
    26281 tcaatggatt ctgaagcatt caagaaaaac cggatcggga tacttgctgg tctgacaaga
    26341 ctgcgacaaa tttgctgcga tcctcgtctg tttattgaag attaccaagg cggttccggc
    26401 aagctcgaac aagtaaaaga tctactggta gctgccaaag agaacaaacg aagagttttg
    26461 ctgttttctc aatttacagg gatgctgact atcttgcaag aagagttagc cgagctaggg
    26521 atctcgacat tttatttaag aggcagtacg aaaccacaag atcggttaag tatggtagac
    26581 gcatttaatg ctggcgaaaa agatgttttt ctgatttcct taaaggctgg gggaactgga
    26641 ttgaatctca cgggagcaga tacggtcatc ttgtatgacc tttggtggaa tcctgccatt
    26701 gaagaacaag ctgctggacg tgcacatcgg atcggacaaa aaaatgtggt agaagtgtgg
    26761 cgtatgatct ctgaaggaac gattgaggaa cgcatggatt cactccagca agaaaaacgc
    26821 gaactgttcc aaaaagtgat ccaaggtaat gaagaacagt tgacgaaact gactgaagaa
    26881 gacatccgca tgattttaag tgtaggagaa atcgaggagt aagagactcg aaaaagtgtt
    26941 cagtaatggg taagaaagcc tttctaaaga agcgattgtt tatttgattt aaaaaatagc
    27001 aaggaggctg ggattccatt ttatcccagc ttccttgcta tcattttttt atttctattt
    27061 ttaaaggtta tacaaagatt gtcttcattg tctctaacag ctgatcaaaa gaagaaatct
    27121 cgatatcgca aattggagtc tgttcaattt tgcgttctcg atggttgaac caaagcgctt
    27181 gccagttagc actttttgca cctagaacat cattgtcgta attatcgcca acgtataagg
    27241 tctcttctgg aagcatatga aattctttct cagctagctg aaaaatctct ttttctggtt
    27301 tttggaaacc tgttgcttga gaaatgagca tattgcggga aggaatccaa ttgttcaatt
    27361 gaagttgctt cagttttttt gtctgatggt cagtcggccc atttgtgata attcctaatg
    27421 ggacattctt ttccttcaag aaatcgaggg tttttttgac ctcctcatgc aagcagatat
    27481 tatcaagttc ttcctcgtaa attttttgaa ataagaggcc atcttcttcc gtaatatgag
    27541 ggtagtctaa atcttttagt gattggctga tccgatgtgc tcgcatatat tctagtgtcc
    27601 aatctcctgc cattactttt gggaagtttt catcactatg atggcggaac cggatatata
    27661 gtggatgcat atctgcatct gaaacaagcg gaacgactct tttgaccgcg tttcgaaatg
    27721 gctgctgctg atcatacatc gtatcatcaa catcaaacac aactgattta atcaaaattt
    27781 tacacgcctt tcggttttca ttgatttttt cacaaatcct tgactattgt aacagaaaaa
    27841 attgtctaaa aaagctgata aataaaggtt tttcttacta tatttctatt tccttgacag
    27901 aataaggttt ttatatttca gtttttttca ctaaaaatcg tgaaacacgt caataagttt
    27961 gatgaacaaa ttaatcatta tggtagaagt cgattgattt attttaatgc aatctctgtg
    28021 gaattttcga aagatttatt tttttaatac agtctcaata taactattca aacataaaat
    28081 aacgttattt gatttatttg tttatagtaa attttattta gtaatcattg ctttaaaata
    28141 ctacgcttat ataacagaga aaataagcgt tataataaag aacagtatta tttaaaatga
    28201 cagaaaacat tactattaaa gaaataaaaa acataaaaaa tcttaagaaa tcggtttcat
    28261 ttagcttttg agataaaata atagtacagt tttatacgct gtttcatatg tttagaaaat
    28321 ttgaattaga tttgaaaact ctaattttta aatgataaaa aaagcgagaa tgctggtttt
    28381 actgtatatt aaccttagat aactttcatt tttttaaaaa aattatgaaa aaaaggtagc
    28441 tatttaaaag ttgattatgt ataatagaaa cagatgggag attattatga tcttctgtta
    28501 caaaaaagtg attcttatca cgaaaaggag tggtgcacgt tgttaacatt atatacttcc
    28561 ccaagttgta cttcctgcag aaaggctcgt gcgtggttgc aagaacatca gattccattt
    28621 gttgaacgta atattttttc agaaccattg aacagttctg aattaaaagc gattttacaa
    28681 atgacagaag acggaacaga agaaatcatc tcgacacgtt ccaaagtatt ccaaaaactg
    28741 aacatggatt tagatgatct gccgttacaa gaattattgg aacttgtgca aaacaatcct
    28801 ggattgcttc gccgtccaat catgattgat gataaacgtc tgcaagttgg ttttaatgaa
    28861 gatgaaattc gtcggttcct accgcgcgat gtacgacaat tagaattacg tcaagcacaa
    28921 ttgatggctg gattatagaa ggataatacg aaacttggaa aagactatta caaagatagt
    28981 ttttccaagt ttttttgttt ttacaaaaag tattcttgat tagatgtata aaaaggtagt
    29041 agaagatgat gattgcacga aaaatagaga gggaaaatta gctgaaaagt cggctatata
    29101 gtattcgtct gccaaaaatg ttatagttaa ataagatagc ttgaaaggtt gaaaaatccg
    29161 ctggttttat taaattcgct taacagcgag attttttttc tttacattta agctgatttc
    29221 gctacaatga atctatatta aacattgtgg caaagtgagg tgtagcaaaa tggaaatgga
    29281 acatattaat gaaaatacga tccgtgtact aattggtcat gaagatttag aggaacgggg
    29341 cgtttcattt ttggatttac ttggcaatca caaagaaatc gaaaatttct tttatagtat
    29401 tttggaagaa gttgatatcg aagaggagtt ccgaggaagc gaagctgtca ctttccaagt
    29461 tttgccaaaa ggagacggat tagaactgtt tatcagtaaa aatcttccgg atgaagaaat
    29521 ttctcaatca gaagattcta ctgttgattc agaagatgtg agtgactttc ttcgtcagca
    29581 gattattggc agcgatccgg aggaagaatt atctggaagc gccctagaag aacaggaaag
    29641 acaagcaact tttgcttttg aagattttga acaagtgatc caacttgcaa cagatgtcga
    29701 actagagtct gcttggactg atttgtattt attcgaagag cgctattacc tagtcgttca
    29761 cttctggatg gaaaatctca accaagcgga tgtagagaat cagattgctc gaattttgga
    29821 gtttgctgaa aagagcgatc gtacaccaga aacattgaat gaatatggac aatgtctgat
    29881 ggcgcgtaat gctatcgagc gaacgaaatt ttattttgta taaatcagca ttatagtaag
    29941 agactgtgac aaaaattgtg tcgcagtctt tttttcgtat aaatgtgttc aaaagcttgc
    30001 atctgcggta acaagcccaa ccaaacgaaa aatattggga actatttttg tttagctgtt
    30061 cttattactt gatgcagaat agctttttca cgccctcttt tttcgtgtaa ataaattctt
    30121 agacgtaaat aagttcagag ggagaaaaat gctgcttgca atgaatgaat ataataagtg
    30181 ctgttttgct aaacatgcag aaaaaggaaa gaaatattat tgtcgtggct gtcgaaaaag
    30241 agtgattttg aaaaagggaa agaaaaaatg tgctcatttt gcccatcaaa aatcagataa
    30301 ctgttcggtc tttagtgaaa gagaatcaaa agagcactta cagttaaagg aatgcttcat
    30361 ggattggctg ggacagtcag tagaaccagt atttttggaa gcctatttgc cgaggttgcg
    30421 gcaaaggccg gatattttgt tggcgaatct agcaatagaa atccaatgtt ctagactgtc
    30481 tcaccagaga tttattgaaa gaacccaaaa ttatttgaat aacagttacc aagtatggtg
    30541 gatacttggt aattcttttc ttggacaatc gcaattctca ttgatagaaa aaagttgctg
    30601 ctactataat agaaaaagag gagtgcattg ctggaaagct gatctcaaga aacaaaagct
    30661 ttatttgtat catcatatta cagagactgt atcagggcat atttcctttt gcagtagctg
    30721 ctggactttt tctagtaggg accttaaaga aatattcact agtaacgaaa ttaaaatgaa
    30781 ccaaatgaaa aaaatagaaa aagtgagtga agatgggaag aaatggctga cacgccaact
    30841 tattcacaag caaaagaata cagtatccat acaagaacaa tgctacttgc gtcataaaca
    30901 tcttttgcat ctatcatcgt ggatctatca aaaaagtcgg tttttctttt atttacaaga
    30961 acaggttttt ctttatcgaa tgttgtacga agaagccttg gaaaaccaga aagttcctga
    31021 tttcaactca tggctttgcc aaataaaaga acataaaagg gaatggcttt ttcctatgat
    31081 tgatgaagag atggtctatc agcagttttt taacgaatgc atacacttgt cttctttgaa
    31141 aaaatagtaa gtataaaaat aggctaggaa tcggttttct atgtaaaaca agatttagtt
    31201 atgctaaaat tgatggaagc agacacatga atgagtagaa aagttagatg ctgtgacatg
    31261 tggatgttag actatgatct attttgatag atagagctaa gggaagaaaa ggagtggatt
    31321 tcatggaagt aaagcagttg ccaaaacgag aagaattgcc tgaaaattta acttgggact
    31381 tgaccaagat cttttcaagc gaccaagagt ttgatgagaa atatttggaa ttatcagaag
    31441 agttaaaaca atctgaaaaa cacaaaggaa cacttgatca aggcgcttct caatttttaa
    31501 atgcgattga attcgtattg agggtttatc gccaaactga agtcatttat gtatatgcgc
    31561 accttaaaaa cgatcaagac actggaaata cagattacca agcgctttat gcaagagcaa
    31621 gcagtctgtt ttcgaaagtt agtgaagccg tttcctggtt tgaaccagaa atattgcaat
    31681 tgtcagatga ccagatttgg caatatttca aagaagaacc aaaattggaa gtctatcgcc
    31741 attatatcca gcaaatagta gataatcgag cccatgtctt atctgctgag caggaatctc
    31801 ttcttgctgg agcaggtgaa atctttgatg cttcaagtga tacatttgct gttttgaata
    31861 atgcagatct agtttttcca acgattgaag gagaaaatgg tgaaatagtc caattatctc
    31921 atggcgtgta tggtcagttg ctagaaagca cggatcgaag ggtgcgcgaa gcagcattta
    31981 aggggttgta cagtgtttac gaacaattta gaaatacatt tgcttctact ttaggcacac
    32041 atataaaagg acataatttt aaagcgaaag tccgtaatta cagctctgcc agagaagcgt
    32101 ctttgagcaa taatcatatt cctgaaagtg tatacgatac tttggtagac gtggtaaaca
    32161 agcatttgcc tttgttacat cgatacatgg aattacggaa acgtttatta gaagtggaaa
    32221 aactgcacat gtatgatctt tatacaccgg tcttagggga agctccaatt acctttacgt
    32281 acgaagaagc aaaagaaaaa gctttagaag cactgaaacc aatgggtgaa gaatacatgg
    32341 ccatcgtaga aaaagcattc tctgaacgtt ggatcgatgt tgtcgaaaat aaagggaaac
    32401 gaagcggtgc ttattcttcg ggaagctatg acacaaatcc atatatttta ttgaattggc
    32461 atgatacgct ggatcagcta tttacgcttg tccacgaaat gggacatagt gttcatagtt
    32521 atttcactcg ttcgaaccag ccttatgtgt acggcgacta ctccatcttt ttagcagaaa
    32581 ttgcttcgac aacgaatgaa aatatcctaa cggagtattt attggaaaca gaaaaagacc
    32641 ctcgtgtacg ggcttatgta ctcaaccatt acttggatgg gtttaaagga acagttttcc
    32701 gccagacaca attcgctgaa ttcgagcatt tcatgcatac ggaagatgaa aaaggtgtgc
    32761 cattgactag tgaataccta agtgatagtt atggtaaatt gaatgcaaaa tattatggtc
    32821 cagcagtcga agaagaccca gaaattaaat tcgaatggtc acggataccg catttttatt
    32881 ataattacta tgttttccaa tactcgactg gcttttctgc tgcttcagca ctggcgaaga
    32941 aaatactaaa ccaggaacca gaggcactag agaactactt ggcttaccta aaagcaggta
    33001 acagcgatta tcctgtggaa gtaatgaaaa aagcaggagt tgatatgaca caggctgcat
    33061 atattgaaga tgcaatgtcg atgtttgaac aacgtctaaa tgaattagaa gaattgatcg
    33121 atcgtttata aggctttcta tttttgattt tctcgaatag aaacgaaaaa aatacgtcgg
    33181 ctctcttgta agggagtcga cgtatttttt
//
LOCUS       DAKCAA010000028        33022 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000028 DAKCAA010000000
VERSION     DAKCAA010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.028"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            3..1154
                     /gene="fucO"
                     /locus_tag="OUE31_001432"
     CDS             3..1154
                     /gene="fucO"
                     /locus_tag="OUE31_001432"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HCU0222447.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            1281..2039
                     /locus_tag="OUE31_001433"
     CDS             1281..2039
                     /locus_tag="OUE31_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HCU0222448.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            2139..2783
                     /locus_tag="OUE31_001434"
     CDS             2139..2783
                     /locus_tag="OUE31_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HCU0222449.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            2790..3797
                     /locus_tag="OUE31_001435"
     CDS             2790..3797
                     /locus_tag="OUE31_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCU0222450.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            3813..4655
                     /gene="kduI"
                     /locus_tag="OUE31_001436"
     CDS             3813..4655
                     /gene="kduI"
                     /locus_tag="OUE31_001436"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HCU0222451.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            4675..5478
                     /locus_tag="OUE31_001437"
     CDS             4675..5478
                     /locus_tag="OUE31_001437"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HCU0222452.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(5727..6791)
                     /locus_tag="OUE31_001438"
     CDS             complement(5727..6791)
                     /locus_tag="OUE31_001438"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HCU0222453.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(6788..7873)
                     /locus_tag="OUE31_001439"
     CDS             complement(6788..7873)
                     /locus_tag="OUE31_001439"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HCU0222454.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(7886..8863)
                     /gene="mvaD"
                     /locus_tag="OUE31_001440"
     CDS             complement(7886..8863)
                     /gene="mvaD"
                     /locus_tag="OUE31_001440"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HCU0222455.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(8856..9800)
                     /gene="mvk"
                     /locus_tag="OUE31_001441"
     CDS             complement(8856..9800)
                     /gene="mvk"
                     /locus_tag="OUE31_001441"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HCU0222456.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            10116..10775
                     /locus_tag="OUE31_001442"
     CDS             10116..10775
                     /locus_tag="OUE31_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCU0222457.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            10860..11765
                     /locus_tag="OUE31_001443"
     CDS             10860..11765
                     /locus_tag="OUE31_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCU0222458.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(11767..12399)
                     /locus_tag="OUE31_001444"
     CDS             complement(11767..12399)
                     /locus_tag="OUE31_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCU0222459.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    12550..12675
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            12719..13243
                     /gene="infC"
                     /locus_tag="OUE31_001445"
     CDS             12719..13243
                     /gene="infC"
                     /locus_tag="OUE31_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HCU0222460.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            13315..13515
                     /gene="rpmI"
                     /locus_tag="OUE31_001446"
     CDS             13315..13515
                     /gene="rpmI"
                     /locus_tag="OUE31_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HCU0222461.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            13568..13927
                     /gene="rplT"
                     /locus_tag="OUE31_001447"
     CDS             13568..13927
                     /gene="rplT"
                     /locus_tag="OUE31_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HCU0222462.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            14179..15516
                     /locus_tag="OUE31_001448"
     CDS             14179..15516
                     /locus_tag="OUE31_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HCU0222463.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFCGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            15564..17693
                     /locus_tag="OUE31_001449"
     CDS             15564..17693
                     /locus_tag="OUE31_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HCU0222464.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            17668..18357
                     /locus_tag="OUE31_001450"
     CDS             17668..18357
                     /locus_tag="OUE31_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222465.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(18765..19451)
                     /locus_tag="OUE31_001451"
     CDS             complement(18765..19451)
                     /locus_tag="OUE31_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCU0222466.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(19587..19781)
                     /locus_tag="OUE31_001452"
     CDS             complement(19587..19781)
                     /locus_tag="OUE31_001452"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222467.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(19831..20271)
                     /locus_tag="OUE31_001453"
     CDS             complement(19831..20271)
                     /locus_tag="OUE31_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HCU0222468.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(20275..21120)
                     /locus_tag="OUE31_001454"
     CDS             complement(20275..21120)
                     /locus_tag="OUE31_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HCU0222469.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLEKQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            21269..22687
                     /gene="pepV"
                     /locus_tag="OUE31_001455"
     CDS             21269..22687
                     /gene="pepV"
                     /locus_tag="OUE31_001455"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HCU0222470.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(22763..23965)
                     /locus_tag="OUE31_001456"
     CDS             complement(22763..23965)
                     /locus_tag="OUE31_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222471.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
     gene            complement(23952..25739)
                     /locus_tag="OUE31_001457"
     CDS             complement(23952..25739)
                     /locus_tag="OUE31_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222472.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            complement(25752..26705)
                     /locus_tag="OUE31_001458"
     CDS             complement(25752..26705)
                     /locus_tag="OUE31_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCU0222473.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            complement(26890..27240)
                     /locus_tag="OUE31_001459"
     CDS             complement(26890..27240)
                     /locus_tag="OUE31_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCU0222474.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            27440..28519
                     /gene="pepA"
                     /locus_tag="OUE31_001460"
     CDS             27440..28519
                     /gene="pepA"
                     /locus_tag="OUE31_001460"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HCU0222475.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            28662..28982
                     /locus_tag="OUE31_001461"
     CDS             28662..28982
                     /locus_tag="OUE31_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCU0222476.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            29004..29468
                     /locus_tag="OUE31_001462"
     CDS             29004..29468
                     /locus_tag="OUE31_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCU0222477.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            29664..30269
                     /locus_tag="OUE31_001463"
     CDS             29664..30269
                     /locus_tag="OUE31_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HCU0222478.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(30308..31597)
                     /locus_tag="OUE31_001464"
     CDS             complement(30308..31597)
                     /locus_tag="OUE31_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HCU0222479.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            32025..32504
                     /gene="rlmH"
                     /locus_tag="OUE31_001465"
     CDS             32025..32504
                     /gene="rlmH"
                     /locus_tag="OUE31_001465"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HCU0222480.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            32707..32985
                     /locus_tag="OUE31_001466"
                     /pseudo
     CDS             32707..32985
                     /locus_tag="OUE31_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
BASE COUNT        10568 a         6123 c         6786 g         9545 t
ORIGIN      
        1 aaatgagtaa tcgaatgatt ttaaatgaaa catcgtattt tggaaaagga gcgattgagt
       61 cgatcgtccc tgaatttcag cagcgaggat tcggcaaagc agctgtcatt actgacaaag
      121 gattgatcga gcacggtata gcaacaaaag taacagaact tctagataaa gcagcaatcg
      181 cttatgcttt atacgacggg atcgtaccta atccaacgat ccaaaatgta aaagatggag
      241 tggcttttgt taaagaggca gaggcagact gtttgatcgc aatcggtgga ggttcgccaa
      301 tcgatacggc aaaagccatt gggattattt tgacgaatcc agagttttca gacgtcatta
      361 gtttagaagg tgttgctgat acgaaaaatc catgtttacc tatattagct ataccaacga
      421 cttctggaac agcagcagaa gtaacgatca actacgtcat cacagatgaa gtaaatcacc
      481 gaaaatttgt ttgtgttgat cctcatgata tcccaatcgt cgcgttcatc gacagcgata
      541 tgatgatggg aatgccgaaa aaattggctg catcaacagg tatggatgct atgacgcatg
      601 ctattgaagg gtttatcaca aaaggcgctt gggaaatgac tgatatgctg catttaaaag
      661 caatcgaaat catcggccat tctttggaag tttctgtaga tggcgatcaa aatgggcgag
      721 aaaaaatggc attaggacag tatattgcgg gaatgggctt ctcaaatgtc ggtttaggac
      781 tggtacacgg gatggctcac ccgttaagtg catggtacaa cattcctcat ggcgtagcgt
      841 gtgcagcact tttgccaact gtcatgaaat ataacaaaga atatactgga gaaaagtacc
      901 gtgagatcgc tcttgttcta gggattaaag gagcagctga aatgtcttta gaagatgtaa
      961 gagaagcggc ttgtggtgag atcgatcggt tgagcaaagc ggttggaatc ccagaaacca
     1021 tttctgaatt aggtgtaaaa gaagcagata ttccagcaat tgcagaagat gctttgcgag
     1081 atgtatgcac accaggaaat ccaagagaaa cgacagtaga agaaatcatt gctttatatc
     1141 aaagtttgat gtaaaaacga agcggatctt caacattaaa ttgcctgtaa agagaaatgg
     1201 tagtttatat ctggatatct cttttaaatt gatggtattt ccgctataat ttttcttata
     1261 aagaaatagg agaatattat atggaaaata aaaagcctta tggaactgta ttgatcaaag
     1321 cctctaaaat actagactat ttagcggaaa accaagatgt ctctttgcag acgatcgcaa
     1381 agggtgtggg aatgacctct tctacagtct tgaaaatact agatactttg ttgatgatcg
     1441 gctacgtaaa taaaaattca gagaaaaact atcgtttagg tgcaaagctt attcgctacg
     1501 cgaataaaaa cattgaacaa atcgatttgg tagagttgac tttaccgttt ttagaacagc
     1561 tgcagcaaaa gatcgatgag actatccact taggggtatt ggacaacaat gagatcttgt
     1621 acgtgaacaa actagatcca aaacatcaaa cgatccgcat gtcttcaaaa atcggaatca
     1681 cccgaccatt atacaattct gcgatgggca aagccgtatt agcagaattc agtgaagagc
     1741 agtacactga ttatcttgaa aagcatccgt tgatccctta cacagaatat acgatcacca
     1801 atgcattacg gttgaaaaag gaaatccaaa cggtaaaaga aacccacatc gcatttgacg
     1861 atgaagaaat cgaacgtgat attttttgta taggagcctc aatcgtgaaa aacgaacaaa
     1921 tcattggtgc atttagtgta agtatgccga aatatcgttt aacagatgag acaaaagaac
     1981 aaataatcag tgccctcaag caaacaaaaa gcgaaatcga gcaaagaatt caaaaataat
     2041 gaaaaaagcg tttgcaattt ttcttttctg ccgtataata tgggtataga tttccaagtt
     2101 ataaaataaa atttctaaat aggaaatagg tggagaagat gaaaaaaatt gatattttat
     2161 ctcgattgaa aaacgccgga gtgattgcgg tggtacgcgg aaaaagcaaa gaagaagctt
     2221 tgaatgcttg ccacgcaatc atcaaaggtg gtctaactgg tattgagttg acttttacag
     2281 tccctcaagc agatcaagta atcaaagaac ttttgtcatt ctacaaagac caaccagaaa
     2341 tagtgattgg cgcaggcaca gtattagacg ctgtcacagc tcgcttggct atcttagctg
     2401 gcgcagagta tattgttagc ccttcctttg atcaagaaac ggcagagatg tgcaatctgt
     2461 atcaaattcc ttacttacca ggatgtatga ctattaccga gatcaaaaca gcgctgaaaa
     2521 gcggggtaga tatcgtcaaa ctatttcctg gaagcgctta tggaccaagt atcatttctg
     2581 ccttcaaggc gccgatgcct caagtcaata tcatgccaac tggcggtgtg agtctggaca
     2641 atatgaaaga gtggttcgat gctggtgtcg taacagtcgg agtaggtggg aaccttttag
     2701 cacccgcagc tacaggagat tttgacaaag taacggaagt cgcgcaacag tatgcagcaa
     2761 aaatgaaaga aatcaagagg tagctgctta tgggaaaagt agtgacactc ggagaaatca
     2821 tgttgcgatt gtccacagag cagggaaccc gtatcgattc aagtgaacga ttcgctgccc
     2881 attatggcgg aggggaagca aacgtagcaa tttctttagc taattacgga catgaagcga
     2941 tttttgctac aaaagtacct gataacgcat tgggaaaagc agtcaaaaag cacttgcaat
     3001 gttatggagt agatacgaaa caggtattat ctggtggatc aagactaggt acttattata
     3061 tggaaactgg tagtggcgaa cgcgccgcct cagtgatcta tgatcgtgcc ggatcaagtt
     3121 ttgctgaaat ggatcatttg gaatggtcgc tagaggagtt attccaagga atagatatat
     3181 ttcatgtttc aggaatcacc ccagctttgt ctaaaaaatg gcaaaaaatg acgaaacagg
     3241 tgatagaagc tgcaaaaaaa gctggctgcc tgatcagctt cgatatcaac tatcgtggaa
     3301 aattatggac acagcaagaa gccagcgaag taatccatca gcttttacct ttagtagata
     3361 tctgctcagc tggaaaaatg gatgctcttt atttgttagg tatcgagaaa gcgccagaag
     3421 cagaagaaca acctctaatt tattattatc aaaaaatgca ggaaaagttc ccgaatattc
     3481 aggtgtttta ttcgaccaag cgtaccgttc attcagcaag tgaaaatgaa ttgaagggga
     3541 cattgtggat gaaccatgaa tatgtggaat cccaagtcca tagaatcacc ccaatcgtgg
     3601 atcgagtagg tggcggagat gcttttgcag gtggcgtgct ccatgggatt ttatccaata
     3661 tgtctccgca agaaatcatt gattttgcta cggcagcttc tgccttgaag catacgatcc
     3721 atggggactg caaccaattt agtcaagaag aagtcgcaca atttttagca tgcggctctg
     3781 gaaaaatcat tcgatagaag gagtagaaga aaatgcaaga aatggaaaca cgttatacac
     3841 acagtccaga agatatccgt cattattcaa cggaacaatt gagaaaagaa tttttagtag
     3901 aaaaggtatt tgaaccaggg aaaatcagtt tgacttatac gcacaacgat cgaatgatct
     3961 ttggtggagt gacacctact gaaaaagaat tagaaatcac attagacaaa gaactaggtg
     4021 ttgattactt cttagagcgt cgtgaactag gtgtgatcaa tatcggtgga ccaggattca
     4081 tcgagatcga tgggcaaaaa gaagaaatga aaaaacaaga cggatactat atcggaaaag
     4141 aaacacgaca tgttgtattt tcttctcaag atgctgaaaa cccagctaaa ttctatatta
     4201 gttctgttcc agctcatcat aaatatccaa atgtaaaaat cagtatcgac caagtaaaac
     4261 caatggagac tggtgaaggc ctgacactga atgaacgtaa aatctaccaa tacatccatc
     4321 caaatgtatg cgaaagctgt caattacaaa tgggttatac gattttagaa ccaggaagcg
     4381 cttggaatac gatgccttgt catacacatg aacgtcgtat ggaagcttat gtctactttg
     4441 attatgccaa tgaagataca cgtgtgttcc acatgatggg caaaccagat gaaacaaaac
     4501 atttagttgt agacaatgaa caagccatta tttcgccaag ctggtcgatc cattcaggtg
     4561 taggtacaag caattactca ttcatctggg caatgtgcgg agaaaatatc acctatacag
     4621 acatggatat ggtgcaaatg gatcaattaa aataagcata agggagagaa aatgatggaa
     4681 tttagtatgg atatgtttcg tttagatgga aaagtagcat tagtcaccgg tgctgtctat
     4741 ggtattggat ttgagattgc acgctcttta gctacagcag gagcaaaaat cgtatttaat
     4801 aacttgaatc aagaatcagt tgatgaaggt atagcgcatt ataaagaagc aggcatcgat
     4861 gcaaaaggtt atgtctgcga tgtgaccgat gaagaagcgg ttcaagcgat ggttcaacag
     4921 atcaaagaag atgtaggttc agttgatatt ctagtcaaca atgcagggat catcaaacgg
     4981 acaccgatga tcgaaatgga tgcggcagac ttccgccaag taatcgacgt ggatttaaat
     5041 gccccattca tcgtttcaaa agcagttatt ccggatatga tcgaaaaagg cggcggtaaa
     5101 atcatcaata tctgctccat gatgagtgaa ttaggacgcg aaacggtcag tgcttatgct
     5161 gcggcaaaag gcggattaaa aatgctgacg aaaaacatcg cttctgaata cggtcaatac
     5221 aatatccaat gtaatggaat tggaccaggt tatattgcta caccgcaaac tgctccatta
     5281 cgcgaaacac aagaaaacgg tgaacgtcat ccattcgatc aatttatcgt tggacgtacg
     5341 ccagcagcac gctggggcga gccaatcgat ttggctggac catctgtctt cttggcttct
     5401 agcgcatctg atttcgttaa cggccatgtc ttgtatgtgg acggaggcat acttgcctat
     5461 atcggaaaac aaccttaaaa gagctttagt acactgttta gtggagaggt tgtgaaatca
     5521 gcggattgaa cgaataccga aggacagctg attaaacatc atttattcga aaaaagaggc
     5581 tgggacagaa gcatttaact ccaagaaata agaaggaatt cacgaaaatt gcttttcaaa
     5641 tttttgtgaa tttcagctta tttccgaagg agttgctttt acttccgccg tttgtacgtg
     5701 tttagagcgt gagacaaaag tgttctttac ttttgtccca cgctcttttc tgtgcgtctt
     5761 ccatacttca ctaagtcgat ccctcttgct tcgcaccaat ccttcactgg tccggaaaag
     5821 atcagagatt gttggtgtag ggccgcggta ttcgttgcgc cgaccatagt ataaagcaga
     5881 cgaagctctt cttgccattg cttcatcagt ataatagttt cttctacgcc gtgattcatc
     5941 agatgcgtca gtacggttcc tgaagtaccc acggcatttg cgccgagaca aagggcttta
     6001 aatatgtcat aggcattgcg gatacctccg gaggctagga tttccataga agtgtctgct
     6061 tcatttgctt caagcaatga agagactgtc gattgccccc agtcagctaa ataactcagt
     6121 tcccgcttgg agcgacgggc gttttcgatc tgggtgaagc ttgttccgct tcgaccgctg
     6181 atatcaactg tatgaactcc taaagcagct agatcattga gcgtttctct tgtcatgcca
     6241 aaaccgactt cttttacgat gagggggacg tcaatggctg tttgagtttc ttgaataagt
     6301 actttccaat tggtaaaatc acggtctccc tcaggcataa ccaactcttg aggtgcattc
     6361 aaatgaatct gtaaggcatc tgcgtgaaac aatcggatag cttctttggc tctttcgaca
     6421 gaagtccctg caccgatgtt ggcaatgatt ttcccgtgag gatattcttg tcgcataatc
     6481 gtataagtat cggctaaaga agggactttc aaggcagcgc tgactgaacc agtggcaatc
     6541 atcaaatctg cttctcttgc gacgattgca agatcttggt tgattttttt tgttttttcg
     6601 cttccgccag tcatcgcatt gatataaaat gggctgctta gtgtaaaccc aactgcctgt
     6661 gtacttagat cgacatcaga aactgctatt tgcggcaaag ggttatggat gatccgtacg
     6721 aagtcaaatt cgtttttttg tttatcatga aaggctttag ctagtgaaac atgttcgtct
     6781 tttcgattca tcggttttcc tttctttgat cgctatagac atgtaacggc agtggagtga
     6841 tttctgcttt ttcccatgca ctcattaaag gaagaatgcc agatttctgg tcaacaatta
     6901 cgattccgca atcgccccca cctgcaccag aagattttgc ggctccttca tactgttcag
     6961 ctaaattaca caatttgttc aaagcaggcg tttcgatgac gaccccagtg attgcagata
     7021 aatcatgcag taattgtcgg ttttttcgaa tcatctgttg gatcaacgtt acattatttt
     7081 ctttaaaccc tttgatcatt tcgttgacac attctgtact attttttaag aaaagctgat
     7141 aagccaccat tttatcttct ctcgaacggt gaacttgatc gaccaaatca gaagtagagg
     7201 cagggctacc cgtccaacca atcaataaac gtaaatcttc aggagcaatc aatggctcaa
     7261 tggatagacc tggccaatcc agggcaagta actcactgat agaatgctga gtttcttgtt
     7321 cttggagcca aggatggtcg aaggttgaga aagcgatcca gccaccataa cagctagcag
     7381 cgatgtcgcc gcaggaacca ttatcttgaa ctgctaaatt ggctagtgct gcaatcttga
     7441 aaatctccaa ctgagataaa ttcaacgcgt aaaaaacatt caaggctttg accgttgcaa
     7501 cggtcacggc accgctagaa cccaatccat atttccggcc atttgaactg tctaactcac
     7561 ttgttacttt cagatcataa aaggataaaa gaatgttttt ttcttgtgca tacttttcag
     7621 tcaagcgaat agcagcaagg atataatgaa aaggattttc ccgaatatct aaaactaatt
     7681 ctccgttgcg tcttgtccaa cgtacaggca tcccactata ttgtgcagat tggatacttc
     7741 cgacttttcg tgcagattct acagtgactg tcacgaattg atcgactgca gcgataactg
     7801 ctggatggcc tgtttcaaca actgcatatt ctccggcaat atagagtttg cctggtgcag
     7861 atacttcaat cataaaaatc tccctttatt caataatcgc aattcctgga ccagcatgtg
     7921 cagtaattac ttgttctttg ctaaataatt tggtaaatgt ttcttgtacc tcagataaat
     7981 ggctgttttc cactaaaact ttgacattag ggccagcatc catcgtaaag tagcatggaa
     8041 tgccttgctt tctcaattgt cgcaccgcat ccatcgcttt taagctgtca ggagaccagt
     8101 aagtgaatgg aggctgggca gctaaagtcg ttccatgcat ttttagtccg tttctttcca
     8161 tcgtttctcc gagaagttgg aaatcttttg ttttgattgc ttgtttcaat tgatatagat
     8221 ccccttcaac ggaatctaac cagccttgat aaaaactgga tgtttcgact gtccgacgca
     8281 tcccatttct gctggacact tcttttttct ggtcgttgat caaaacgaaa accattgcta
     8341 aatcgtcttc gaaagaatcg gaagggactg gcttagcgta agaacttaag tcgtcatggc
     8401 ctttttccca ttcgacgaaa ccaccgaaaa tacttcggca agctgaacca gacccgcgtc
     8461 gagcaaatct tgaaagagag agatcatcta atccaagctt aagagcagta ttgcaagcgc
     8521 ctgctaaagc agctagcccg ctggcagagg aggctaatcc agctgcggta ggaacgaaat
     8581 tctgactgat tactgaagct tttagtgaga ggccggcttc tttacgaaaa aggtcaagaa
     8641 actgactgac tttttttgtt gctttttcgt cttgcaaggt gccatctaga taaaattcat
     8701 ctaccatata gctatcagaa aagatgactt ctgtctctgt ataaaatgca tccaatgtta
     8761 acgaaaggct gttgttcatt ggaaggatga gttcttcatt tttcttaccc caatatttga
     8821 ttagagcaat gttggtatat gcgcgtgctt tgcctttaaa cataggtatg tactcctaat
     8881 ccttgtatcc aagtttcagc agcacccgca tcttcaagtg cttgactgat ttcttgggct
     8941 tttgtttttg tttgtgctaa tgcaatcata cagccaccgc gtccaccgcc agttaatttg
     9001 gcacccaatg ccccggtatc ttttgctgtt tggatcaata gattaagaaa atcattgctg
     9061 attgtcagct tttccagaag tgattgtgat tcatccattg tctgtgccaa cgtttctggt
     9121 gaattttcaa tgattgcttg ttttgcttgc ttcgtcaagt atcctaattt ttggatcatt
     9181 tgtccagttt catgaggctg ggtttcaaag aggtgagcga catctttgac ggcttctctt
     9241 gtttgtcctt tgattcctgt atcagcgaca atcaaaaaag catcgatgtt caaagaaaag
     9301 tagtcgaaag gatgcccttt tgtaaaataa atcggctgca agctgctagt agcggctgca
     9361 tcgattccac taggattacc gtgggcgatt ttttccgaaa gctggacatt ttctaatagt
     9421 atttcacgag acaaaggaaa tgctaagtaa tcataaaaag cacgagtgac tgctgtggcg
     9481 actgcagcgc ttgatcccat tccacgttca gcaggaatcg tgctttcaat ggtcagttgc
     9541 aagttttttt ggatgtcatg ctgttttttt aagtgaatga ataatttttt gatatttttt
     9601 aatgcatgag gagcttcggc taaatttcct gaatagtagg aagaaaccag ttgatcgtcc
     9661 attgcatcca gctcttcaag gaatgcggtg acttttgttg catagaaagg aaaggcaatc
     9721 gctggttctc cataaacaac cgcgtgctcg cccatcaata tgatctttcc gcttgattct
     9781 ccttggccat agtttgccat aatctaactc cttctcacgt aaaagtgatt tttaagcaaa
     9841 aaataaagcg cccaaaacga gttgcgctgc ttcacgaatt tttttgtcca ctaagggtct
     9901 caaaaaacat tcctccttta ttttactaaa accatctcag aagtaaaact aagaatacgt
     9961 tttctaaaga aaaaacactt ttttcttaag aattttttga ctttttttct tctttgacta
    10021 gaaaaaaata caattgacac tactagatat tgggggtata tttaaaaagg ttggagttaa
    10081 acacaatatt tagtgatgaa gtgagctgga ggtaaatgag cgtgatcgtt ttagcaggta
    10141 caattggtgc cggaaaatca agtttaacag aaatgatggc tgaacacttt gatagtcagg
    10201 cattttatga atcgattgat gataatgaag tcttgccctt attttatgca aaccctgaac
    10261 agtatgcttt tttgctgcaa atttattttt tgaataaacg ttttgcaagc atcaaacaag
    10321 caatgaaaga tgacaataat gtattggacc gttcgattta tgaagattca ctgcttttcc
    10381 atctaaatgc agatctagga agagcaacag aaacagaagt tcgtgtgtat gatgaactgc
    10441 tggaaaacat gatggaagaa cttccctatg ctgcccataa aaaacatccg gatttattag
    10501 ttcatattcg tgtatctttt gatacgatgt tggagcgtat cgaaaaacgt ggtcgttcgt
    10561 atgaacaatt gtcctttgat ccaagtctat acgattatta caaagaattg aacagacgtt
    10621 acgatcaatg gtatgaagaa tacaaagaaa gtccaaaaat ccaaatcgat ggagaccgct
    10681 ataattttgt ggaagatcct caagcaaaag aagaagtctt gaaaatgatc gaagaaaaat
    10741 tagcagagat tcgccaaacc aaagtagcca tttgatttac agttgctcaa ataaagggta
    10801 aacctttatt tgagcgactt ttttctttat actggaaaca aatgtcagga ggatagagta
    10861 tgcgggaaaa acactatttt aatcaagacc gtaatttttg gatcaatgta cagcaaaacg
    10921 atgtgctagc tgttaaaaac ttaaaagaag aatatggcat tagtgacgag atgctgactt
    10981 attctctaga taaaaatgaa cgggcgcgcg tagagtacga ttcttttgat gaagcgttac
    11041 tgcttgtatc aaatgttccg caccagcaaa aagtcgataa tcattatgaa actagtccta
    11101 tcgcttttat tttaaaagaa gacggtttgt ttacatttac cacgccgaat accgagtacg
    11161 tgattcgact aattcgatcg cttttggaac gaatgccaga catgagtgta tacagtttat
    11221 tgtttcgtac attgtttttg atttctgatt ccttttttcc tttaatcgag gaagtgaata
    11281 gtgaacgtca gcggcttaat ctgaaattaa gagaaaaaac aacgaacaag aatctgctgc
    11341 aactttcaga tttagagatc ggtttggttt acttagttac aggaacaaaa caaaatgtag
    11401 tacttttaga acaaatcaag gcattggcta tttatcgcaa gttgtcagaa aaggaaaaag
    11461 aagagttgga cgatgcgctg atcgaagcac gacaagcagt tgaaatgacg aacttagctt
    11521 cgcagatttt agaccagctc tctggcactt ataataattt gctgaataac aacttgaatg
    11581 acacgatgaa atttttgacg gtctggtcgc tgatcttgac cgttccaact attgtgacag
    11641 gattcttcgg aatgaatctc cagttaccct ttacccattc cgttttcgga tggggaatcg
    11701 ccttgatcat cagtttggtc ttatctattt ggatgcttat tgcactgtgg cggcggattc
    11761 gttgatctag tctttgatct gcaaaccaag ggcttgggcg atcacaagtg cttgctcttg
    11821 gttgacgatt agtcccgcca aagaatcttg agataaagcg attgctgtga agaaattagt
    11881 cgtaaagtct aatcccttca gagaagttcg aaaccagttc gaaccggtca actgattgtc
    11941 agacaaaaaa aggtttttcc aagtgacctc ataaaattcg ctgtcttcta attgacaatg
    12001 atcgaaggag acagctttca agtttgtact actaaaggaa gccatcgaag caatacaatc
    12061 agtgaaagta cagtctcgaa gataactttc ggcaaaattc gtacctgtta atttacattg
    12121 atgaaacacg acttggtgga aactgccacc aatccactcc agattggaaa aatcacattt
    12181 ttcaaaaatg acattactgc attcaaaatg acgtaaaact gttttttgca tcgtaagttt
    12241 ttggatatga ctctctctta ataccatatt tttggcatcg agatagcttt ggtcaccccc
    12301 gttgatcaga agaccagaga agatctcctc atcttctaaa taaaactctc cctttgtaag
    12361 aagaggaaga gaaggtggaa taggttcgat ttttttcatg tgggttcacc tcgtttttct
    12421 ttagtatagc aaagaagcgg gaatcactgc tagaaagtct gctaatctaa tcattttcag
    12481 aaaaggaaga caaactgtat gaaaaacatt gacaaaaaga ttagtttttg ctatactatg
    12541 atggttgaga aataaaagca gaagcacccg cttctcgcct tagttgataa tgtcactggg
    12601 ctagatagtt ttcactggtt ctattaggtg aagtacgcgc gggttctgta agagaactcg
    12661 tttttttatt gccgtttatt cggtaagctt ttctttctct cataatattt ggaggtgaat
    12721 gaccatagca aaggatatga tggttaacga cggcattcgt gcacgagagt tacgattgat
    12781 cggttcagat ggtgagcaat taggagttaa gacaaaagca gaagcattga atattgcaga
    12841 acaagcaaac ttggatcttg tgttagttgc ccctggtgcg aaaccaccag ttgcgcgaat
    12901 catggactac ggtaaatacc gtttcgaaca acaaaagaaa gaccgcgaag cgcgtaaaaa
    12961 acaaaaagtg atcaatgtaa aagaagttcg cttaagtcct acgatcgact tgaatgactt
    13021 caatacaaaa cttcgtaatg cacgtaagtt cttggaaaag ggcgataaag tgaaagcttc
    13081 tatccgtttc aaaggccgtg ccattaccca taaagaaatt ggtcaaaaag tcttgaatcg
    13141 cttagctgaa gaaactgcgg atattgcaac agtggaacaa aaagcgaaaa tggacggacg
    13201 cagcatgttc ttgacgctgg caccgaaaaa cgacagtaag taatttgaat gactaactgg
    13261 ctgttggaca gccgatagtc ggataacgaa agattttgag gaggaaatat agtcatgcca
    13321 aaacaaaaaa cacaccgcgg atcagcaaaa cgtttcaaac gtactggtaa aggcggattg
    13381 aaacgcttcc gcgcgtttac aagtcaccgt ttccacggca aaacaaaaaa acaacgccgt
    13441 caattgcgta aagcaagcat ggtttctagt ggcgacttca aacgtattcg ccaacaacta
    13501 gcaaaaatga aataagaagt acaaataaca gaatctgaag atttattttt attaggagga
    13561 attatacatg gcacgtgtta aaggtggaac agtaactcgt aaacgtcgta aaagagtgct
    13621 aaaattagca aaaggttact acggttcaaa acacacttta tttaaaacag caaaagaaca
    13681 agtaatgaat tcatacaact acgcatatcg cgatcgtcgt caaaagaaac gcgacttccg
    13741 taaattgtgg attgctcgta tcaacgcagc agctcgtatg aatggcttga gctactcaaa
    13801 attaatgcac ggtttgaaag ttgctgaaat cgacatcaac cgtaaaatgt tagctgactt
    13861 ggctgttaac gatgcagcag catttactgc attggctgac caagcaaaag aagctttggc
    13921 taaataagct aaacaattat aaagaggaaa gaagataacg aaaagttatg ttctttcctc
    13981 tttttttatt tacaatcctc catcaaatga aacaggacaa taacgtataa gtctaaaata
    14041 gcataattaa ggttttttaa ttgaaaactg aacatttatg gtcacccttt aatgaaagcg
    14101 ctaactacat aagttagaat gagtttgact gatatattag tttgcttatc agaaaaacaa
    14161 aatggacgga ggaataacat gagtgatatt attattggta ttttgttagt tatctcattc
    14221 tttttcatgg tctggtactg tgtaaaaggc tacaacttga tggtcggctt tgccatcatg
    14281 gctactgtat ggatgggatt agcgctagtc ggaaacacgt tttcaccaaa cccggcgatg
    14341 gaagggcaag gagtaattga tgtgttgacg catatctata cgacggggcc agctgagtac
    14401 gccaaatcga tcttggtaaa tgtcttcttt ggtgcctttt tcgggcgtgt tctagtagat
    14461 agcggaatcg cagctaccct gattcgaaag gtagttgaac ttggagggga caagccaaga
    14521 atcacgatga gcttactatg tattgtaacc gctgttatat tcatgtcgat gacaggaatc
    14581 ggaccagtga tttctattgc agttattgtg ttgccaatct tgatgtcatt aggtatttca
    14641 gtaccggttg cactgttctc atttatgggc tcgattatgg ctggaatctt tgctaatatc
    14701 gtcaatttca aacaatatca aacgatttat gctggtttca atccagcggc tgaaagctat
    14761 acttataatg actatttcca aattggtatg attgggatga ttgtaagctt agttgtggta
    14821 ctaacggtcg ctaatatatc aatgaacaaa aagaaacgct atgcaatggc agcaaacgta
    14881 ccagctgaag gtggcgacgc accaatgatc tcatggttag ccgtattatt accagtttta
    14941 ggggtcgttc ttttagatct tccaatcatc ttaggtttta ttctagcagg tatctgggca
    15001 ttgctgttta ctggaaaatt gcgcggaggt tataaagaaa tctgtcgtca gtttgcgaaa
    15061 ttatttacag atggcgcagt agatgttgca ccaatggttg gtttcttgat gaccttagcg
    15121 atgttcaata attcagctgc gtatgcttct ccttattttt cagctatttt tggagattgg
    15181 ataccgcaat caccattagt cttggcaatc gtatttgcta tattgacacc actaggattt
    15241 ttctgcggtc caatgaatct agtcggttca ggctcagcta ttttagctgt cgtattagct
    15301 gttaatccaa cgatgtcgcc agcctttttg ttcccgttat ttgcaatcac aacgattgct
    15361 cctcagcatt tagatattac acaatcttgg gttgcttggg gattaggtta tacaaaagta
    15421 acttctcgag aatatatgaa gaaatccatc ccaactggtt ggatcatcgg agcgatctta
    15481 tgcctgatca cgttcttatt gtacgggaac gcctagtaaa caaaacgtcg ataaaaacga
    15541 ttagatgaat ggaggaaaag aaaatgaaac gttttgtgcg aatgggaatt gatgttggcg
    15601 gtacacatac gaaagcagtc gcaatcgata atgcgacgca cgaaatcatc ggaaaatctt
    15661 cagtgaaaac aacccacgat gatgtccgtg gagtagccgc aggtgtcgtt cagtcttttc
    15721 aaaattgttt gcgggaaaat aatatcagtc cagaagatgt tgtgtttgtt gcacattcta
    15781 ccacacaagc gactaatgca ctgattgaag gagacgtagc aaaagtcggc gtaatcggga
    15841 tggcaaaagg tggattagaa ggttttttag caaaacgaca aactagattg aacgatatcg
    15901 atttagggaa taagaaaaaa atagagattg tcaatgcatt cttacctgtc aaacacttaa
    15961 atgtagaccg tgtttcagaa acgatttctt ctttagaaag agaaagagcg gaggtcttgg
    16021 tttcttctat ggcatttgga gtagataatg gggaaccaga acgagttgtt tatgaagcag
    16081 catcggtaaa atcgatccct acaacgatgg cttctgacat cacaaaatta tatggattga
    16141 caagaagaac tcggacagca gcaatcaatg catctatttt accaaaaatg ctagatacgg
    16201 caacctctac agaagattcc gtacgagaag caggggtcaa tgtttctttg atgattatgc
    16261 gcggagacgg cggagtaatg gaaatcaatg aaatgaaaaa acgacctgtt ttaaccatgc
    16321 tttccggtcc agcagcatca gtcatgggct ctttgatgta cttgagagcg tctaatggtg
    16381 tttattttga agtaggcgga acaacaacca atatcggggt cattaaaaat ggacgtccag
    16441 caatcgatta ttcaattgta ggtggccacc caacatatat ctcttcatta gatgttcggg
    16501 ttctaggtgt ggcaggcggt tcgatggtac gggctaatca gtcaggaatc atcgatgtcg
    16561 gtccacgttc tgcacatatt gccggtctag attatgcagt atttacggag acagaaaaaa
    16621 tcaaaggtcc taaggttgaa tttttctctc ctaaagaagg agaccctgct gattacgtca
    16681 aggtagtgat ggaagacgga gaagaagtga ctattacaaa tacatgtgca gccaatgtcc
    16741 ttggattagt gcaagaagaa catttttctt atggaaatgt cccatctgca cgaaaagcca
    16801 tccaagcatt agctgattat tgtcatacga cggttgaaga catcgcagaa cagatcatgg
    16861 aaaaatccta tgctaagatt gaaccggtga ttttagaatt ggcagacaag tatcacttgg
    16921 agaaagatca gatttctctt gtaggtgtag ggggcggcgc tgcctcattg attacttact
    16981 ttagtaataa aatgggtgtg aaatattcga ttcctgaaaa cgccgaagtg atttcttcta
    17041 ttggtgtagc acttgcaatg gtccgagatg ttgtagaacg tatcatccct tcgccaagta
    17101 aagaagatat acgatcgttg aaaaatgaag cgatgaataa agcgattgaa tcaggcgcta
    17161 caccagaatc gatcgaagtc cacgtagaaa tcgatccaca gacttcaaaa gtaacggcta
    17221 tcgctactgg ttctacggaa gtgaaagcaa ccgatctaac caaggagatc acaacagaag
    17281 aagcactaga gcttgctgca gaggatatgc gattaaataa aaatgaagtt tgcttattgg
    17341 aaaatacacc tttcttttat gtatgcggcg aacagaatcg ttcaaaaaat gctggaagtc
    17401 ttcggatcat cgatcaaaaa ggatttatca aggtccaacg tggacatgct tcatgtatga
    17461 aaacaactgc agccaattat atgacagctg tcgaacaact ttgggaagat atggcagttt
    17521 atcaaactga attgattgcc cgaccagaat tttatctctg cttaggagca agagtctctg
    17581 attttacagc gacggatctg gaacaactac agcttttgat ggatctggaa gtatctacta
    17641 tggaaccgga ggaagaagtg atcgtcgttg ccggaaatat caaacaaaca taagttagaa
    17701 gagttactaa acgaattaca acagatcccc gaagaaattt ggggattcta ccagtttcgg
    17761 cgagatttat tttggaaaaa gattcctttg tccaagcaga aaattcttat acaacaatca
    17821 atcgattgtg gtatcgaaac ggcatgtagc atcaaaaaaa agtacccttt tgccgatgta
    17881 ggagaaattt gtgaacaaat ggctgttcca atcgtttcct gtgaatcaga gcaaataaac
    17941 gaacgaatca cttttgcaac ttatgcagaa gatgaaggga ttcgattgat gacggagccg
    18001 ttagaaaaat taaaatgttc aggactagct tcgatctcta aagaaacagc gcaagctttg
    18061 attattggac atgaactatt tcaccacatc gaagcttctg ttaagggaat ttatacgcaa
    18121 agcgaaaaaa ttgtgctgtg gcggttgcct ttttatacac atcaatcaaa cattcgtgca
    18181 ttgagcgaga tagcagcgat gagtttttca aaagagatga atcaaagcga tttttcgcct
    18241 tatgtattag aggcagtctt actttggcca tataatgaaa ttcgtagcca agggatctta
    18301 gaagaaataa aaaaaataga aaaaagatgt acggagtatg atttagatta caaataaaga
    18361 gactgtgaca aaagtcgtgt cacagtcctt tttttccgaa taaacgatgt tctcctgtca
    18421 actcctcggt cacaagtcaa aatattcaac aaacatgaga agctgttttt tgaaattgtt
    18481 ccttgtgact cggagatgaa cggcaggctc acgacctctt ggaaaacggt gttcaaaagc
    18541 ttgcatctgc ggtaataaga acagccaagt taaaaacata agaagctatt tttacttggc
    18601 tgttcttatt acttgatgca gggcagcttt ttcacaacct ctcaataaac ggtgtgcaat
    18661 cagctgaccc tcggtattag ctcaaaaaaa acggcaaaat atgaggaact attttgccgt
    18721 ttatttctct aatactcagg tcaaaacgct gattccaaaa cctcttattt gatgggtctg
    18781 tcctgaatat cttcaaaata atcggggtaa ttatgaatca cgtattcttg ctcctcgata
    18841 atcatatgta aatgcatcgt gcaaagaaat ccgacttcat caaagttatg atcaatcatt
    18901 gattgaagca ttgtctgatg ttcatctaat actcgacccc agtctaattc tgaaatcgtc
    18961 aaacgtaacc atctgaaacg gttcaagtgc gtactataac tttctagcca atcccaaatt
    19021 tctcgttttc cagcaatttc ataacaagtt cggtgaaaat cagtatccaa atcaaaaaaa
    19081 gcttttttat tttgagcgat cactgcctga tcggtttgtt ctagtatttt ttctagttta
    19141 gcttgatctt gcttggtcat tttcgcactg cattcttgca ggatcggttt ttccaacttt
    19201 tcccgcgtat aacgggctaa tgaagcagat cggatatcga tttttgaaac ataagtgccg
    19261 gactgtggaa tggtttttac aagctcttga ttgcgcagtt ggatcagtgc ttctcgaatc
    19321 ggtgtacgcc cgatagctag ttgttcttct aacactttat cggagatttt acttccaggt
    19381 gctaactcgg aataaatgat ttgtttacgt atagattcat aagcttgctg ttgcaaatta
    19441 ttgataacca tttaaccttc ctttctatgc agatataatc tattataaca taaatcgctt
    19501 acaaatcgtg tgggcataaa aacacagtct gcaaaaaaag ccctgatagg catgcctatt
    19561 agagcctcga aaagaaaaat attgaatcaa tctggtcgta cctcttggat cggtttgaca
    19621 cgaccgccga ttcttttagc aaaagcttcg gattcttttt tgtctttgaa aatgagcaga
    19681 ttgtctaagt ttttttcccg agtgcgacag ccagttttat cgatgtaacc gtgcattact
    19741 ttaacgacat acatggggat cacctgcttt tttcttttca ttatacgaac tactcgacac
    19801 aatacaagaa aaatgcttag acggtattta ttaagaattt acatcatcca aagaagcgta
    19861 cgcttggaat aactgttcta actccggatt gactttgctc agcttcacta atcgttgcga
    19921 atcagaaagt aaaaaacagt gtttactact gccagtagtt tttaattttt tgtcttcagt
    19981 tcccacaatt tcgtagctaa aatccaaccg tgttcccgta tacttttgga tagttgggtg
    20041 gatgctcact ttttctccgt aatggatcat ttctttatag ctgcaattta cttccagaac
    20101 ggggatgatg atcccagatt cttcgatttt tttataggga aaccctagat gtaccaataa
    20161 ggctacccga gcctcttcaa accagcggat ataattgctg tgatgaataa tccccatttg
    20221 atctgtttca taataaaaag gttctcgcac ataacctgta aatttctcca tgactcatgc
    20281 ctcgttttcc attgattttt tacaaaaata attcatccac ttcggaagtg cttcgctgat
    20341 ttgtgtcggc aaaacaatat attgttcttt tgccagctgg tctccaatga aactatgaag
    20401 ataaacagct gctgcaatcg tttggtcatt ttgaggaaac tgggctaaaa atcctgtgat
    20461 catcccagct aaagtgtcac ccatgccgcc tgttgccata gcagcagaac ctaaaggatt
    20521 ggtgtagaag tgctggtgac cataaatttt tgtctcatga cttttcaaaa cgagcacagc
    20581 accgatttcc tgttgcttct ttttgttttc tttatcccgt tgttcttgta tcggtagaga
    20641 actcaaccgt tgccactcca tttgatgagg tgtaagtaca gtttgttcgg gatagggtag
    20701 caaaagatga ttagcaacaa gtaaacttaa agcagagcca tcaatcacca gccattgttc
    20761 ttttgattgt ttttctagta cttgtttgaa acgttccaaa ctcttagaag aagtacccaa
    20821 tccgggacca atcaagagta catctgcttg ctttattacg gaaagaaact ggtcagtatc
    20881 cgtccaatct acaatcattg cttctggcag atgactgtga agagcactcc gatttttttc
    20941 atcagttact acagtcgtga gacccgctcc actgtgtacg gcagctaaag cactcataat
    21001 gattgctccg ccatattgtt cattgccgcc aatcaaaacg atacgtccaa atgttccttt
    21061 atgtgaaatc tttggacgag gtgtgatgac tcttttcact agttgttcgt ttatcagcat
    21121 cgaaaaacct ccttttactc attatagcgt atattttttt tagagaaaaa cagataagaa
    21181 aaggaattgt cagatttttt gaactatttt tttctgtaat ttgtggtatc atgaacacga
    21241 agacttaaat aagtggagga ttaactttat gacaattgat tggcaaaaag aagtagaagc
    21301 acgtaaagaa gacttgcttg aagacttgaa aaatctttta cgtgtcaaca gcgagcgcga
    21361 tgattcaaaa gtaacaccag atgcaccatt tggacctgga cctcgcgacg cattgaaaca
    21421 tatgttagct tatggcgaac gtgatggatt taaagtaaaa aatgtcgata actatgcagg
    21481 gcatattgat cttggcgaag gagacgaaac gctagggata tttggacaca tggatgtcgt
    21541 tcctgcagga gatggctggg acacagatcc ttatgaacca gtaatcaagg atggaaagat
    21601 ctttgcacgc ggatcaagcg atgacaaagg tccaagtatg gcagcttact atgcgatgaa
    21661 gatcattaaa gaacttgact tgaaactatc aaaaaaagtt cgcttcgtag tcggcagcga
    21721 tgaagaaagc ggctggggcg atatggctta ttatttcgaa catgaagaag aaccagattt
    21781 tggtttctca ccagatgctg aattcccaat catcaatggt gaaaaaggaa atgtttcttt
    21841 agctttacgc ttcaaaggcg acaatgcagg agattatgtc ttgaaatctt ttgtttccgg
    21901 acttcgcgaa aatatggtgc caggaacagc aactgcagca cttcaagtac caagtgcaga
    21961 tgcagctatc gcgatggaag aagcatttta ccaattcatc gaagcaaatc cagtaagcgg
    22021 aacgattgaa gcggacaata cgtatgtaaa aatcgaatta gttggtaaag gcgcacatgg
    22081 tgcaagccca caatctggta tcaatgcagg ttctttcttg gcattgttct tagataacta
    22141 tgaattccta ggatctgcta aacaatttat ccatgtagca gctgcttatg tccatgaaga
    22201 tttttatgga gaaaaactag gagtcgctta tgaagatgaa aaaatgggca aattgacaat
    22261 gaatgctgga ctatttgctt ttgaagaaaa tggtacagag gaagcgaact tcatcaatat
    22321 gaatttccgt tttccaaaag gtgtaacagt agacggattg caaagtgaca tcgaacaaac
    22381 agtggggcaa gaaggcgcaa cagttactcg aggtgctcgc gtaatggaac cacattacgt
    22441 accaatggat gatccattgg tggctacatt attgcaagtc tatgaagacc acactggaga
    22501 aaaaggctac gaacaaatca tcggtggcgg aacttacgga cgtttgttga aacgtggcgt
    22561 tgcttatgga gcgatgttcc caggatatac tgatacaatg catcaagcaa acgaatttat
    22621 gagtcttgat gacttgttca gagcaacagc aatctatgca gatgccatct atcgtttggc
    22681 gaaataaaaa tactaaaaaa ctccggctat ctctgacagc tggagttttt atgtttaaaa
    22741 atgaattagt acatcggtat tcttaaaagt aatttagttc gtcttttgat ttctcaggag
    22801 ggatcaaaaa ggcgaaagca ctaagtatag caaaacttgt gatgatttgc gtacgatacg
    22861 taaaccaata atgaatctgt gagtgattag ctaaaatatt gtaccaaata tacggcgtta
    22921 cagcagctaa aacaaacaaa actagaagtt ggaacggacg ccagctattt cgtttacgat
    22981 aagcaaaata gagaaaaaca agacaagtaa tcaatagcaa taatattgct acttttggat
    23041 acatcaatct aatattgctt ttcagcatct ctaatcgatg caacgggtat ttgtcgtttc
    23101 cttccgttcg aaagaggatt tggttgattg catcttttac aatgtttttg ttcaatatga
    23161 tcgatgatag gatccattta gccacccatg tcaaaccata gcctaatccc caaaagatac
    23221 cggtaaaaac aaaactgcct acttgtttgc tcaatgaact gcgtttatcc attaaatact
    23281 tatttgttac ataataaata atgatcacag gtatccccca agagatgacc ggtgttgtca
    23341 acaagtcaaa aaagttagct aaagaaccaa tgacaaagaa atacaagaat aattgttggt
    23401 tggtgttgga gagttgtggt tttgttaaaa atagtaatac agacaataaa gtcaaaatcc
    23461 aaatatttga aaattgcata ctgaagaaaa aggttgcagc atttcctata gcaagcgaaa
    23521 tcaacaaggc tgtcgttaaa tagatgtcgc tacacttggt taaaaagtag ctcgtcaatc
    23581 caatcagcag aaaaagaatg gctgcgtaaa tcattcgaat actccccaaa ctcatcccta
    23641 gcagtaaagg tcgtaaaaaa agctgataac catgccaata acggggataa tccgccatag
    23701 acatcgcgtt ctccaaggag ttcaattcag gatctgcttt tgtttttcgt atcatcaaat
    23761 gatcagtaaa attatctaac cgagtgccta gcatatttcc ttgattgata gaaggataca
    23821 ttccttcttt ttcaaccatc tgtagagatt tttctgcatt cgattcaata gagtgctgcg
    23881 gaatgaaaaa agtaattgtc agtagtacgc aatagctagc gatcaagaga acaaaagcaa
    23941 aaaatatctt tttaaatagt ttcatgagta tctcctatat ctgttttcat tttttctctt
    24001 ttatctagta aaaaaggaga gaggatataa acaggtagac ctaatgctaa aacaaacaca
    24061 taccgtaaac taaaagccac aggagtagca atcataatag tagcaaaaac aagcataccg
    24121 ggaagaaaaa ggagtaaata ccgatatttt ttcttaaaga ttgctaaaag tgcactgccg
    24181 atagctaacc acagtaatgt gccggaacca aagaaatcac gagcatcgat gatttttttc
    24241 attcctgaca atccagtaag atgttcaatc aaatctactt gcttcatacc ataattattc
    24301 gtgtttacac gagtatctaa aaagccgtaa ctattttttg taccaggtac ccagaacccg
    24361 aacgtttcta aaatataagc atctgtatag atttttatat tacttggtaa atttcttgcc
    24421 catagtgata gaaattcttt tttatgtgta ttcaaaaact cattgttaaa atttttatgc
    24481 cacttgattg agtctgcaag actaggagaa tacgcttcat aatcttttat cgggagtagc
    24541 tgattcatga atgctttatc tttcttagac aagtcaccat ccataacaat agttctagaa
    24601 atttgctgca aaggaacacc taattgttca gcagtttctg taggaatagc ataacgagcc
    24661 atcaacgggt ggatgagtag tccagcaatc actgtataac ccagcaccac ttgaaagaat
    24721 gcttgatacc ttttttgttt caaaataatc aagccgcaaa tcaaacctgt gccggttact
    24781 acataaatcc cattatttct tagataggtg gtcagtaaag caaggatgat tacgtaaatc
    24841 tgattgagaa tcgttggctt ttctcgttga aaaataaagt caaaaaccgc taaggaaaat
    24901 aaaaagcaag cgatagagaa caaagtatct ttttgcatgt tcaaggcgta gattggaaaa
    24961 accggtgcaa atgcaaaata gcataaacta atgagtaccg gaaaaaaatg gatgtttctt
    25021 tttaacagcc agcaaagaga ataacttatc gctgaagctg ttatcaatgt ttgaaaaatc
    25081 gaaaataaaa atacaccgtg attgatcgta tcagttggta aatcatgaac aaatagcttg
    25141 accagtaagg tgaataagac tggatgatga ttgcttatag gaacatcacc catagattgg
    25201 gcgaccgaac ttaacgaatc aggcaaaacc actccaggat acaatgccaa cagataagga
    25261 agccaacaca gaactaaaaa gacagtaaag aataaaaaat attttcttga agagaaagcc
    25321 tgtgtgtttt gagcagtaaa aaatgtttcc agttttggca ttgataaata aatcgattgt
    25381 aaaaataaaa aagaatacac aaaaatggag aaataaacaa gaaagtaaaa aatacttcca
    25441 tcagcaatcg ttgtctttgt atagtttgct gagacatact gaaattgtat ctgtctgcca
    25501 atagaaagtg taagagcaaa agctgcagaa aaaaacaatc gggcaatagc tgcaactttg
    25561 ttttttattg aaaacaactc tattccatat tgcttaaaag caagtagcaa aaccatggct
    25621 aaaccaatga ttactgttgg attcaaagtt cctagaccat aagaagtaaa aaaagcaaaa
    25681 cctgacgcaa ataaagttgc aaaaaaagta ggaaatagat tctccttttt cttatgcata
    25741 aaaaaggcct cctacttcat ttctttattt tgatattcgt ggtagacatg gtataaattc
    25801 aattcatatt ctttcttggc atttgtgacg accgtatcca aaatcaaccc tgttactaat
    25861 gaaagaaggg ctaaagtcat caatccagta cttaaaatcg cagaagggat gcgtgtaata
    25921 aagcttgtca gcatatattc acgaatcaca ggaatcccca tgaccaatcc aaataaaaag
    25981 aagaagatgg tccagatccc aaagaaaagc aaaggtttat aatctttgca cattttgatg
    26041 atcatcatga tcactttgaa tccgtcagag aatgtattca attttgattc gctaccttca
    26101 ggacgatcgc gataatcgat tggaatctca acgaacttga attttttatc taaagcatga
    26161 atcgtcaatt ctgtttcgat ttgaaaacca gaactcataa tagggaagct tttgacaaaa
    26221 attcgattga atcctcgata gccggtcatg acatcgcgaa tttttgtttt atataagtaa
    26281 gtaattgtat ttttaaccag attattccca aaatcatgga aaggacgctt attttcatca
    26341 aaataggttc catttgatag acgatcgcca atgaccatat ctgcttcgcc agaacgtaat
    26401 ttctcaagca aaccatgtgc agcttctgca ggataagtat catcaccatc taccatcaaa
    26461 taataatcgg catcaatatc aaaaaacatt tgacggatta cattcccttt tccttgacgt
    26521 ggttctttct ttacgattgc tccgccttga acggccaatt cgtatgttcg atcggtcgaa
    26581 ttattatcat agacataaat atctgcttct ggtaattccc ttttaaaatc ttcaataaca
    26641 gttgaaattg tcgcctcttc gttataacaa ggaatgagca cggcaatttt ttcacgtgat
    26701 tccatttgtc actctcctta tataataaaa ctaatcttat ttcaataata ccgtataata
    26761 actacaaata ctagctattc caagaggaaa tagccctatt tttataaaaa tcacccacta
    26821 taaaagaagg ataggatacc tctcttttag atagtgggtg cgtattcgtt atttcatttt
    26881 tttgacgtat taatctattg cgcccttttt tcttgaaatg tctaatacgg ttcctgtatg
    26941 agcatctgct aaaaattcat aataaacagt ttcgccatct tctatccggg aaagcccacc
    27001 ccgataagca ctcgaccgaa cggcgaattt ccgaataggt tctttttcaa aagagatcca
    27061 agcaccttcg attgcgcctt cttttaaaaa agatgttttg atattttcaa gcacttggtc
    27121 tgctgataac acttttttgc gatgatacca aatcgttgaa gctaccccac tcaataatcc
    27181 tagaccgatc ccaacggcta acccgccttt aaaatagctt aattcgcttt cttcatacat
    27241 gtggatatac ctccttcttc tcacttgcta ctctttgtgt ttattttacc acactctcat
    27301 attttctttg aaataaataa ccgctaccag aaaaaataag ctataataaa tacgatcggt
    27361 ctgcagaaaa aatcatattt tatccgcaga tcaatataag tctgagagga gtttagtctg
    27421 aaatttagac gaatagcata tggaagaaaa aacatttcaa cgaatcaaag agttaacaga
    27481 attacaagga acaagcggtt ttgaacaaga cgttcgcgcc tatatggaaa gtcatatgga
    27541 accgctggta gatgagttac agttagatgg tttgggcggc atttttgggc tgcgccacca
    27601 tgaagaagcg gatgcacctc gtgtaatggt cgcagcacat atggatgaag tcggattcat
    27661 gctgacacaa atccaagaaa acgggctttt taaagtcgta cctctaggcg gatggaaccc
    27721 ttacgttgtt tctgctcaac gttttacact taaaacctct actggtaaga attatccatg
    27781 tatttcttct tccgttcccc cacatttatt acgaggaaca agcggacaaa aatcagtaga
    27841 agtaacagat attttgttcg atgctgggtt tgaatcaaga gaagaggcaa tgagttacgg
    27901 tgttcttcca ggagacacaa tcgttcctta cgctgaaacg atcaaaacag ccaacgggaa
    27961 gaatatcatc agcaaatcgt gggacaaccg ctatggctgt acaatggtat tagaagcttt
    28021 agaagcgtta caaaatgaaa cattaggtca tacattgatt gcaggcgcga atgtccaaga
    28081 agaagtaggc ttgcgtggtt ctaaagcttc tgtcaataaa ttcaagccag atctgttctt
    28141 tgcagtagac tgctctgcag cagatgacac agtgacgaaa aatggcacat tcggacattt
    28201 aggagaaggt acattgatgc gtatccaaga tccaggtttg atcatgcttc ctcgtttgcg
    28261 tgagtacttg ctagatatcg ctgaaacaaa caacatccct tatcaatact ttgtttcaaa
    28321 aggcggtaca gatgcaggtg ctgctcatac acaaaatgaa ggaatcccaa gtacagtgat
    28381 tggcgtagtg ggacgttata tccatacgca tcaaacgatg ttcagtattc gcgattttga
    28441 agctgcacga gaaatgttga ttcaaacatt gaaaggttta gataaatcaa cagtgaacac
    28501 gatcgtatac gggaaataac gcgatagtga aactataaaa tctggcaaaa gcaacctttt
    28561 gtcagatttt ttttataaaa agaggatcaa tgtttgttag ttcgaaagaa aggtgtataa
    28621 tttaattgaa aaatacataa acagaaagta gaggaaaaag aatgattatc ccaaatagtt
    28681 tagaagaatt agcaggctac gtagaaactg gaaaaagtgt atttttcttt actgccggct
    28741 ggtgcggaga ctgccgtttt atcaaaccgc aaatgcctga aatcgaaaat gacttttctg
    28801 attggcaatt tattgaagta gaccgtgaca agtacataga tgtagccgct gaatggaaca
    28861 tttttggtat cccaagtttt gtcgtgatcc aagacggaaa agaattaggt cgtctagtga
    28921 ataaagatcg taaaacaaaa caggaaatcg aatcgttcct agaaagtgta ataaaaggct
    28981 gacatctgtt aggaggggtc aagatgaatc aagaatataa gaacatttta gtaggtattg
    29041 acggtagtga acaagcactt gctgctttca aaaaagcgtt agaagtggct cgccgtaata
    29101 atgggaaagt atatgtagca aacgtaatcg atcagcaatt ttataatttt atgggctatg
    29161 ctcctattga tcaaaatcta gtcgatcagc aaactgaaac agccaagcaa atgatcgaag
    29221 aatgtaaaga atatggaaaa tctgttgatt acacaaatat agaaggaatt attgcatacg
    29281 gctctgttcg tgaatccatg gcagtcaaat tgccaaaaaa atatgcaatc gatctaatca
    29341 tggttgggca gtctggacta aatgcagtcg aacgctttat gacaggaagt gtagccagct
    29401 acgtcatacg tcattcacct tgtgatgtct tgatcgtttc tgacgaagaa gaacagccaa
    29461 gtaattaagc aagtggaact tgtataacct ttttaatcaa acagtaaagg gactgtgaca
    29521 aaagtcttgt cacagtccct tgttacgaat aaatggtgtt ccagaagaag cttcttcgga
    29581 aataaagcat gaaaaaaatc tcatgcagtg aatgcaattt tttgttaaga taaatctcag
    29641 caaaggataa tggaggaaag aacatgattt ttgcttataa caaagcacac gtcggagaca
    29701 ctttgatggt tatcatagcc gacgataaag gaacagaaaa cactgtcgaa cgtaaatgga
    29761 atgttgctcg gatcaaagat gaacaaggtc aagttgttgc ttggaacttt ttccatatct
    29821 ccgatcatct aacaattgaa gggaacggcc aagtaagctt aacagatgaa gaattagcga
    29881 aattgaatcg attgattaaa gaagcaggat tcgaagaaca gcttgaagct gatcatgaac
    29941 cgaagatcgt tgtcgggtat gtaaaaacat gcgtcccgca tcctgactct gaccatttat
    30001 cgattactga gacagaagtg gacaatggga cagtattgca aattgtttgc ggtgcaccaa
    30061 atatcgaagc tggacaaaaa gttgtcgttg caaaaccagg agccatgatg ccagatggaa
    30121 tgatgatctg gccaggaact ttgcgagggg tagccagcta tggaatgatt tgttctgctc
    30181 gtgaattgca tttgccaaat gctccagaaa aaaaaggaat cttagtattg cctgaggatg
    30241 ccgtagtcgg agaagtattt ccaaaataaa gaggttgtga caagtctttg tcacaacctc
    30301 ttttttatta attttcacta ttttgatttt gttttaatgc cgattgatcg atcgtcaatt
    30361 caacagtagt tgttttttct ttcgagcctt catagtaagt gattttgaca gaatctccca
    30421 cttttttctt atacaaagca gattgaagtt ctacaccaga agaaacttct ttgtcatcga
    30481 tcttagtaat gacgtcgtat tgtttcaacc cagctttttc tgccggtgta gctgtttgga
    30541 catttgtcac gatgacaccg ttagttacag atgaaggaat cttcaagatt tgttcttgtt
    30601 gctgagtaga aacggcagat aagtcgacca ttgtgatacc tagagctgga cgtgtcactt
    30661 ttccgtcttt ttccagttgg ttgatgatat tcactacatc gttacttggg atggcaaatc
    30721 ccattccttc tacgcttaca ttagaagtcg attcagaagt acttgcgatc ttacttgagt
    30781 tgataccgat aacttgtcct tcgatattca ctaaaggacc accagaattt cccgggttga
    30841 tcgctgcatc tgtttggatc gcattgatat tgactgtttc gttcgattca ttcgtacttg
    30901 ttacttgtcg gttcaaggaa gaaatgattc ctgaagtgac agaattcgca tattcagatc
    30961 ctaatgggga accaatcgca atcgcaggtt caccaacctt caaagcactt gagtccccaa
    31021 aagaggcaac cgtttcgact ttgtctgaat tgatcttcaa caccgctaaa tctgaatagg
    31081 catctgttcc aactaattca gcttttacct tcgtaccgtc tttcatcatg acttccaaac
    31141 cttgctgtcc atctactacg tgattgtttg tgactacata agcagtattc ccgtcttttt
    31201 tgtagattac gccgcttcct tcactataag cttccaaatt actatcatct gagctgctac
    31261 tttcttcttg ctgcccgaat aatccgccaa aaccgcttga ttggttttga ctttgtaagt
    31321 tgataacaga aacgacagcg tcttgaactt tatctaccgc tttggtgata tcagaatcta
    31381 cattgacttt gacattttcc acaactgttt caccggcaga attttgattg ccgcttgtag
    31441 cagtagaact attgttgcca gtgcccatcg ctgcataaaa aatgccagct gtcagtagtc
    31501 ctccaacgat ccctccaaca agccccagac ccaacttacg ccagaggcta ttatttttat
    31561 tttttttcat ctttggtgtc acattttttc tatccatgtg ttcctcctcc aattacattc
    31621 atttatctac tgttagtata gtcttatttg ttgactttag tctactttga gactttgaac
    31681 tttttatgaa aaactttagg aaaaatcatt gttttcagat gaaaatattt gattttcttt
    31741 ttccacagat attgtgtaaa actacgcgga taggattgga aaaataaggg ataaaacata
    31801 tccacagcct gtgtataaag tggataaatt cttataaaac gtatgtttgc ctaatgaatg
    31861 tgatgaaata aggtaaaaca acgctgtttt ctgtggataa acctgtggat gttgtgcata
    31921 actgttgggg aaatcttttt aacaaaaata gtcaaaataa acatatagac gaaaaaattg
    31981 attataataa acaaagtgag cgtgaagatc aaaggagaga aaacatgaat atcaaaatta
    32041 tttcagtagg aaaattaaaa gaaaaatact tgatccaagg tatcaatgag tatgtcaaac
    32101 ggctgaatgc ctatgcgaaa atcgaattga tcgaagttcc tgacgaaaaa gccccggaga
    32161 atttaagcga agcgcaaatg agacaagtaa aagaaaaaga aggagaacgg atcttagcga
    32221 aaatcaaaga acaagaatac gtctatggct tagcaattga agggaaaaat cccacaagcg
    32281 aatcttttgc taaacaaatc gaccaattag gtatccaagg aaaaagccac cttgtttttg
    32341 ttatcggcgg ttctttagga ctcagcgaag ccgtcatgaa aagaagcaat gctcagatct
    32401 cttttggcaa aatgacgtat ccacatcaat tgatgcgcct gatcctcgtc gagcaaatct
    32461 accgtgcctt ccggatcaac gcgggggctc cataccacaa ataatgatat tttttaagag
    32521 aaaaaattat ccctatttta aataatagca ataggtagtg gtagggagaa atttataaat
    32581 aactttttta tttgctttgg tagccaagta agttgcaaaa gaaaaataga tactgttaaa
    32641 aagataatgt agacatagaa acaaatacgt aaaattttag ttagaataat ggcaaggaga
    32701 aaaaacatga tagatgaaaa aaagtgttta aaaaatctat tggaggatat ggatgatatt
    32761 gaagaaaaac tatctaaatg gactaggaaa acaaatatat ttcagatact taagctatct
    32821 aaaaatgaaa taagacatag taatttttta gcttttttgt ttgctccaaa tgaaacccac
    32881 aatttatctg atgagttttt taaaatgttt ttgaaaaggt atatagattc taatgatgat
    32941 accaaagttg ctatcaatta ttttgatgct ttacttaata gctacccgtg gtgctagtta
    33001 attttaatat cctaaagaat at
//
LOCUS       DAKCAA010000029        32464 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000029 DAKCAA010000000
VERSION     DAKCAA010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.029"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            353..673
                     /locus_tag="OUE31_001467"
     CDS             353..673
                     /locus_tag="OUE31_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HCU0222481.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
     gene            834..1739
                     /locus_tag="OUE31_001468"
     CDS             834..1739
                     /locus_tag="OUE31_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0222482.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1736..2509
                     /locus_tag="OUE31_001469"
     CDS             1736..2509
                     /locus_tag="OUE31_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCU0222483.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(2686..4110)
                     /locus_tag="OUE31_001470"
     CDS             complement(2686..4110)
                     /locus_tag="OUE31_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0222484.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4321..4767
                     /gene="nrdI"
                     /locus_tag="OUE31_001471"
     CDS             4321..4767
                     /gene="nrdI"
                     /locus_tag="OUE31_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCU0222485.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            complement(4837..6819)
                     /locus_tag="OUE31_001472"
     CDS             complement(4837..6819)
                     /locus_tag="OUE31_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCU0222486.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6833..7729)
                     /gene="murQ"
                     /locus_tag="OUE31_001473"
     CDS             complement(6833..7729)
                     /gene="murQ"
                     /locus_tag="OUE31_001473"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCU0222487.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            complement(7732..8793)
                     /locus_tag="OUE31_001474"
     CDS             complement(7732..8793)
                     /locus_tag="OUE31_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCU0222488.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(9005..9571)
                     /locus_tag="OUE31_001475"
     CDS             complement(9005..9571)
                     /locus_tag="OUE31_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCU0222489.1"
                     /translation="MVKENFVNEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQALAEKVVDLPVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELISYE"
     gene            complement(9599..11101)
                     /gene="eat(A)"
                     /locus_tag="OUE31_001476"
     CDS             complement(9599..11101)
                     /gene="eat(A)"
                     /locus_tag="OUE31_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCU0222490.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            complement(11359..12480)
                     /locus_tag="OUE31_001477"
     CDS             complement(11359..12480)
                     /locus_tag="OUE31_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCU0222491.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            12606..13547
                     /locus_tag="OUE31_001478"
     CDS             12606..13547
                     /locus_tag="OUE31_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCU0222492.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13690..14586)
                     /locus_tag="OUE31_001479"
     CDS             complement(13690..14586)
                     /locus_tag="OUE31_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCU0222493.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
     gene            14868..16208
                     /locus_tag="OUE31_001480"
     CDS             14868..16208
                     /locus_tag="OUE31_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0222494.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16403..16846
                     /locus_tag="OUE31_001481"
     CDS             16403..16846
                     /locus_tag="OUE31_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HCU0222495.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17108..18478)
                     /gene="nhaC"
                     /locus_tag="OUE31_001482"
     CDS             complement(17108..18478)
                     /gene="nhaC"
                     /locus_tag="OUE31_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCU0222496.1"
                     /translation="MVIVLGIAIGVVGLKVSPNITILAAIGMVMLYAVIKKYPTDWLH
                     EGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFKLISVQWFVPSVFVVCA
                     IVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGAVFGDKMSPLSESTNLA
                     AAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASLSSIREVTDILEANFTI
                     SIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQTSLTKLAGVIESGFVS
                     NTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLISTVMERVSRKMTNTPK
                     LIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPTVLGRTLEDGGTVINYL
                     VPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTGWGISKKFVKPQEAVSK
                     TAQLEQ"
     gene            complement(18929..20152)
                     /locus_tag="OUE31_001483"
     CDS             complement(18929..20152)
                     /locus_tag="OUE31_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCU0222497.1"
                     /translation="MTTTLSTNQLKDLIQYRLPEYQALALAIHDHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTGFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDEIGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDAALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAALSTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSEKGLASIAIAAELLANTALDLLREPKLLEKIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20184..21023)
                     /locus_tag="OUE31_001484"
     CDS             complement(20184..21023)
                     /locus_tag="OUE31_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCU0222498.1"
                     /translation="MKKIIRFAVITFVAIIWLAGCSQGKAATTEKKETTVKLGIIGED
                     TDVWDDVKDRLKKENIHLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNEEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENKKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDEHARPYVNIIVARKEDEDNKTYQKIVDAYQTEETAKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(21040..21720)
                     /locus_tag="OUE31_001485"
     CDS             complement(21040..21720)
                     /locus_tag="OUE31_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222499.1"
                     /translation="MTEFFKTYLPNVYLIPDEFIEATKQTLYMSFWTAFIGGIIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILVLVFLSQFISN
                     QLIKKVTH"
     gene            complement(21722..22795)
                     /locus_tag="OUE31_001486"
     CDS             complement(21722..22795)
                     /locus_tag="OUE31_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0222500.1"
                     /translation="MIELRDISVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEAGK
                     IIEKGSSIQIFSHPEEELTKDFIRTATHLDQALETISAHAAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKVTILQKNELDNRIKVIEGGN"
     misc_binding    complement(22854..23092)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(23135..23368)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23445..24116)
                     /locus_tag="OUE31_001487"
     CDS             complement(23445..24116)
                     /locus_tag="OUE31_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCU0222501.1"
                     /translation="MKGAIFDLDGLLVDTERTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVQAAGSPEKVQEVRAKREEYFYQQLTSGAIQLKPYAKEILTDLKERHM
                     KLGIATTTVTKRATDILDHFQLADYFDTFTFGDEVSENKPSPVPYLTALERTGLEALS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYSVEEKEKLNLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(24204..26882)
                     /gene="mgtA"
                     /locus_tag="OUE31_001488"
     CDS             complement(24204..26882)
                     /gene="mgtA"
                     /locus_tag="OUE31_001488"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCU0222502.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASPNGLS
                     EEQIERSRETYGENAISYGKKTPFIIEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGEYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNDTLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEAAETLDTDTINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVAPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELITGEKISEMNDHELAQVAEEHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGKFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKIPFIQSNATFAMLVITTLGIIVGSVLPFTGFGAELGLM
                     PLPGNYWLWLFITVVAYLALVTAVKKIYIRRFQELL"
     gene            27542..27979
                     /gene="ndk"
                     /locus_tag="OUE31_001489"
     CDS             27542..27979
                     /gene="ndk"
                     /locus_tag="OUE31_001489"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HCU0222503.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFATMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKGADAVPGTIR
                     GDYALPGTENIIHASDSRDAATKEIARFFPPFDTNKPSEKAAK"
     gene            complement(28001..28867)
                     /locus_tag="OUE31_001490"
     CDS             complement(28001..28867)
                     /locus_tag="OUE31_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222504.1"
                     /translation="MYDGELIKKLRVNKKLTQTQLAEGICSKTSLVGIETNSVKKVSF
                     GTLKSFLERMNMTLAEYEWIRNQLDEPKKLKKKRRMLDRIQEDSFDPYKEIANNRRHY
                     KKTEDLYYLVLNLHMSKKTEVSETEFEFLRYECRIIEEYLMQVPEYGQFEVSILADFP
                     WIFSDRFIENNYLKIKKRMRRIAQLNNHEQYLFTFLTNLTLFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKSENHQEFFAVIEYTLGKNQRNSL
                     EKKLLAIAKPSS"
     gene            complement(29101..31179)
                     /locus_tag="OUE31_001491"
     CDS             complement(29101..31179)
                     /locus_tag="OUE31_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCU0222505.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPATLGQTEGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTIL
                     YPVTGTNAEQ"
     gene            31672..>32464
                     /locus_tag="OUE31_001492"
     CDS             31672..>32464
                     /locus_tag="OUE31_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0222506.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETREKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAE"
BASE COUNT         9449 a         6825 c         5756 g        10434 t
ORIGIN      
        1 tataattcac cttacttatt gtaagataaa gcttttttta atttattgcc tgctaatata
       61 taaaaataag gtctagttac tgttttttta aatgattaat aaataacaac tcctttctat
      121 gaaattgcaa agcattcatc ttcttttctg ctaacgatat atccgtcaat gcttgttaca
      181 ctttactaaa aagtatgaga ttgccgatat ctggataggt gtgctatact acagaaaaag
      241 atatacgatc tgccaccggg tagtaaaaaa gaggatgatc attccattag gtctttgaag
      301 ggatgattct cctctttttg tgtatttttt atattgaagg aggaacgtat gtatggcatg
      361 gatggaatta atcatagcag gaattttgga agtattctgg tcaacgatga tgaaatggag
      421 tgatggtttt tctaaaatca attattcttt ttacacagtg attggaatga ttgctagttt
      481 ttactttttg tcaaaggcaa tcaaaagttt gcctatgagt ctctcttatc ctatttggac
      541 agggattggc gcagttggtt cggtcattat tggtgtggtc ttgtttcatg ataagctgaa
      601 tctttccact tggttctttg tcgggttgct gctcatcagc atcattggca tcaaaatcac
      661 tagcggtcac tagatactta gacaagcaga caaggactga tcagaaaaag cggggctttt
      721 tatttgatat tcctctttct atgaaaaaac aagaaaataa gactaatgac ctagcgactt
      781 ctctactcat caggtgtatg cttgtactat ctatagaaaa ggagtgaata tttttgaaaa
      841 gtctttcggt ccaagaatta tccaagaact ttggtcacaa acaagccctc agcgatgtca
      901 gttttagctt atctcctggc aaaatcgttg gattagtagg tcctaatggc gctggaaaaa
      961 caacgatcat gaaagctatt ttaggactga tccattactc agaaggaacg atccgtattg
     1021 gtgaaaatga gatttctccc tctagtcata aaggattaga acaagtagga gcattgatcg
     1081 aatatccggg tatctatcca ttcttaacag gttatgatca tctgaagtta ttctctgaaa
     1141 caaacgatgt atctgctatc gacactatcg tgaaacagct caagatggaa aaatacattc
     1201 acaaaaaagc gaaatcctac tcgctgggaa tgaaacaaaa attgggaatt gctcttgcct
     1261 tactgaacca tccgtctatc gttattttag atgagccgat gaacggtttg gatccacaag
     1321 caacaagaga tgtgcgaaaa atcattaccg acttggctac tcagggcacc tctttcttga
     1381 tctccagtca cttactcagc gagcttgaaa aaatggtcga tgagctgatc ctgatcaatc
     1441 aaggaaaaat catcaaacaa tgtacaatgg ctgaattgaa ccaaacagcg caagatttca
     1501 tcgttatctc tacgacaaat gatcaagctg ctcgaacgat cttgacagac gctggatatc
     1561 ccttggaaga tcctgataaa atcaagcttc taaaaaaaaa cgaagagtta ttaggaactg
     1621 ttatccagtt attgtctgca gaaaatgtcc atgtgacaga tgtccagcat ctgacgaatg
     1681 atttggaatc ttccctattg gaaattctgg attcagtaaa gggggaagaa gaaaaatgac
     1741 gttgcttata aaacaagaat tatttaaatt gatcaagaaa aagtcaactg ctgttttatc
     1801 tgttctatta gttgctttgc tcataggaac agcacttcta gccaaaaaat acacgacgat
     1861 cattgatcca gttgaaatga ctgctcagct tttcagtgcc acatcttgga ttgtctttat
     1921 catgattgct gctgcaagta cgatcatttc aatggaatca caatatggta cattgaaaaa
     1981 tctcctttat cgaaagtatt ctcgaggaga aatattagta agtaaatgga tcacattagt
     2041 tatttattct atttatttat accttttagc tattattgtc accgtgctga tgaaactgat
     2101 ccttttccct tcgatttcct ttacggagaa gatttctact ggtcagacac tgatccaaag
     2161 cttattcact tatactttgg gtagttatat cggtttatgg ctaattttaa gtttagtgtt
     2221 gatgattgct tgttttatca atagttccgg tgcctccatc tcagcaggga tcgtctttta
     2281 ttttgcttca tcaatcatat ctggtatcct catcgcactc attcaaaaat gggagtggat
     2341 caaatggaat ccaatcagta tgctgaatct gcaaaaccaa attggcaacg aagagattat
     2401 gaagcaattg actcatcttt ctactaatca aatgctgttt ggcaatttag cttacattgc
     2461 tttgttctta gcattgggat acctcgtatt caagcgaaaa aatgtatgat ggttcattaa
     2521 caaagaagtt gtgacagaag tggccagttt caagaaattt cggcttattt ttagaagaag
     2581 ctacttcttg aacaccattt attcaaaaaa agaagcgatg acacgaatgt tgtcaccgct
     2641 tcttttttga ataaaccaca ggcttcacag cctctcttta tacttctata cgtgaagcat
     2701 cccagtggca aataaaacca ttgcgattac tccgaccatc gtcacaccga taagtaaaat
     2761 cttatctaag tggatatgtt gtacaggttc gttttgttct ttacgtgctt tgaggtaaaa
     2821 ataaatacct ggtaagaaaa gaacaagaac aagcatcact tcattaaagg ctacaactag
     2881 catggcccat acttgaaaag cacttgctaa aaaccctact aaaaattgga cccactcttt
     2941 ccgctgataa gaaagcttca tttggtacag ccctaagaaa agccacgtga agaaaatcgc
     3001 tgctgtacca agtgtataag caaagttata tgcactgtca gtgaataata atgaaagtaa
     3061 aaagacattc gtacataacg tcgtcaatac gatagcataa gttggtgccc catttttgtt
     3121 gagttttccc catgctttag gcaaaagtcc gtcctcagcc atattcccca ttgtttcaat
     3181 cggcaagatt gtccatgaga gccaaacccc aactaaagaa atgatcaaac cgccgttgat
     3241 cacgaccgcc ccccatttac caaccatcat ttcaaataca tatcccatag caggttgcgc
     3301 tttgatcgtt tgcagctgat tcatcgtcat tgtgccatat ggaagcatgg aaaccaagac
     3361 gtaaataatg atcaaaccga atattcctag aatcgttgct ttcccaacat ccgattgttt
     3421 ttttgctcgt gaacctacga cagaagctcc ttcaatacca acgaataccc agagcatcac
     3481 catgatgcaa ctcaatactt gactagaaaa cgggatcggc tgcccattcg cattcaatat
     3541 gatatcgcta gaaaagttat taatgaattg ttggatcgaa aaggtgctga tagctactac
     3601 aataaataaa aataatggca ctaatttaca aaatgtgacg atagcattga caaagctagc
     3661 attttcaact ccacgattca ctagccatgc atatccccat aagaagatcg tactcatcac
     3721 gatcgatgcc acattttgac caccttcgaa tacggggaag aaataaccta atgcactcat
     3781 caacaatgtt gcgaacgcca cgtttcctaa ccagcatgtg agccagtaac cccaaccgct
     3841 gataaaacca gcgaaacggc caaaaccttc ttctgcgtaa ctaaagatcc cgccttttaa
     3901 atctggacgt tttttattga tattattgat cgataaggag agcatcaaca ttgctgttcc
     3961 tacgagtacc cagctgaaga tagctgggcc accagccgat ccggagatgt ccgtcataat
     4021 accaaatacg ccacctccaa tcgctgaacc aatcactaag gcagcaagtg gaatcaaacc
     4081 aattcctttt ttctgttgct ctgtatccat gtaagcatcc tccaaagtaa aaccgctttt
     4141 atcaaaaagt ataacaaacc ttttttattt ttacttaatt aataaaaact ttaatagaaa
     4201 tataattcta ccgacttttt tctcattata caagcaaagc gcctagtccc tttccaaatt
     4261 acaccaccaa aaaaacttaa aaagatgcta tactaaaggg aaagaattgg gggatgatcc
     4321 atgaacattt tatatatatc gatttcagga aatacgcgtg cttttgccaa acatctagca
     4381 gaatatgctg aaaaaatgca tgcagaagat cctgtcaatc ctgaagttac tttaaaagaa
     4441 atccatgaaa atagtgattt tacgaaagaa acagaaccat tttttacttt cgttcctact
     4501 tatttagacg gcgggaatgg gttagacaac ggtgacacag aaatcttgac cgaaacgatg
     4561 cgcgaatatc tggaatacga agacaatcat aaactttgcc ttggtgtagt cggtagcggt
     4621 aataaaaact tcaacaatca atattgtctg acagccaaac aatacgcaca aagattcggc
     4681 tttcctttct tggcagatta tgaattacgg ggaacaccat ctgatgtgac acgcgtttat
     4741 caaattttgg cagaaaaaaa taaataacac aaaagaagaa gctgaaaaat aaatttcggc
     4801 ttcttctttt tatgttctct attgtttcta ttcttattaa gctttgacat ccatcacagg
     4861 tgcttttgct ttcgctttac ctgttttttc caagacaaag ttttttacac gatccatatt
     4921 ggttaccaag acgatcatgg aggtttcttt gtctgctgct ttgattgctt ctaagtcagc
     4981 ttctgctaca agcgtatcag gtgtcacttg ctgtccttct gttactttca catcgaatgg
     5041 cgtaccgcct aagtcaactg tgttgatgcc catgtgaagc aagatttcta agccatttgg
     5101 tgtcgtaatg ccgatagcat gttttgttgg gaaaacagaa cttattactc cagtaaccgg
     5161 ggaatagata tgtccgtttt ctggttctac aaagtaacct tcacccatca ttttttgtgc
     5221 aaaaactggg tcacttgctt tatctaaaga aacaactgtt ccgtcagcaa ctgatgataa
     5281 gatagtcaca ctttcagctg aagcttgagg tactgctttt tcaggtactt catttactgt
     5341 ggctgtttcg gtcgctagtt cttctttttc taaacggtct ttaggaatac cgaagaagaa
     5401 tgtagcaacg aagccaccag cgtaagcagc caataaacca aggatatagc ctaaccattt
     5461 accatcagag atcaatggaa tcaaagcggc tcctgaaggt ccaatagcga ttgctccgac
     5521 atttccgatc attccgatca ctgccccacc gatacctcca ccgatacaag cagtaataaa
     5581 tggacgtcct agaggtaatg ttactccgta aatcaatggt tcgccgattc ctaagattcc
     5641 gactggtaaa gcccctttga tcatttctgt taattctttg tcttttttgc agcggatcca
     5701 taatgccaat gctgcaccca cttgtcctgc tccggccatc gcaaggattg gaagcaataa
     5761 ggtacgacca gtttcatcaa tcatttgtac atggattggc gtcaagatct gatgtagtcc
     5821 gaacatgacc attggcaaga ataatgtacc tagaacgaag ccggcaaatg ctcctccaac
     5881 accaagtacc cagttgatcc caccgaccat gccgtcagaa atgaaccctg ctaaaggcat
     5941 gatgaagaaa atttcgatca gaccgatggc aatcagggaa agagttggcg taacgatgat
     6001 atctaccgca tcaggtacta ctttatgcag ttttttctca acgattgaca ataaccaaac
     6061 tgcgaagata acacctaaga tcccgccttg tccagttgca agagcttcac cggtaaacaa
     6121 gtttttcagt ggtgcttctg gattcatccc tgtcagcatc acaacagccc cgataactcc
     6181 accaagcgtt ggcgttgcac caaaaacttg tgcagcattg atacctgtat agataactag
     6241 atagctaaac atcccgtttt tcaagatgtt catcacatcg atatattgtt gccatgttcc
     6301 tgcgtctagt gttccagctg tgactaagtt tgctaaaact gcggcaatcc ctgccacgat
     6361 cccagtgccg acaaatgcag ggatcattgg tacaaagata ttagagatgt cttttaatac
     6421 cgatttgatt ttagagggtt tttgtttcga tttttgtgcc gctttcattt cttgtgcccg
     6481 ttcgtttaca cggtcttttc cagatgcaga agaacttgct gtagttgcac tagcagaagg
     6541 aagtttttct cctaatttca cgcctgctaa gtcaaccatt tcctgcgcta ctttgttcac
     6601 tttcccaggt ccgatgatga cttggagctg ttcatcctct actacgccaa gtactcctgg
     6661 aatcgctttt aattccgaga catttacaag atcatcattg atgaccttca tacgtacacg
     6721 agtcatgcag tggacaatgc tttcaacatt gcccataccg cctgctcctt gataaatttg
     6781 ttttgccagt tcttccaaag tcaattcgtt ttttgccatg gtcttttccc cctcataagg
     6841 ttccttttac aaaaccgttt gcttcagcta attttgcttg agctgcctct ttatcactat
     6901 ttgtcaaaat catgacgata gccagtttga cattttgatc tgcttcctca aagtactttt
     6961 cagctgtttc gtagtcagct tctgtcgctt gcatgatgat tcgttttgag cgttcaatta
     7021 gtttttcatt tgttggtttg acgtcgacca tcaagttatt gaatacttta ccgataccga
     7081 tcatactgat agtagaaatc atattcaaaa tcagtttttg tgctgttcct gacttcaatc
     7141 gagtagagcc tgtcaaaaat tctggtcctg catcgacttc gattgggaaa tccgcatgct
     7201 cgctgatttc tgcttgttta ttgcaagaaa tcgttcctgt aacagcacca atcgattttg
     7261 cgtaatctaa tccaccaatc acatatggtg tacgaccgct agctgcgata ccaataacta
     7321 tatcattttt tgttaaattc agcttgatta gatcttcttg ccctaattca taagaatctt
     7381 cggctccttc gacggctaca gtcattgctt cttctccacc agcaattagg cctatgacca
     7441 tttccggttc tacaccgaat gtcggtacac attcagcagc atctaataca ccaagtctac
     7501 cactcgttcc agctcccata taaatcaagc gaccaccttt tttaaaggat tcaatcgtgt
     7561 tggcgatcac tggctcgata cttggcagtt ctttttcaac agcagcggcc actttctgat
     7621 cttctttgtt catgagttgg actgcttgag aaatactcat ttcatctaat ccaaaagttt
     7681 cttggtttct gcgttccgtt gttaggttct ctaaattgat tttgctcatt tttatcttcc
     7741 ttcttttctt ataaattgat agttcatacc agctttgatt tggttgatca gcggtagttc
     7801 ttctttgatg actttggcta ctacattcac tttttcatcc gctggcaaat catatttagt
     7861 taattggatc tcacccatat agcgcaaata cttttcgtta tctaaagtaa tagatccttt
     7921 catacgctta gctgtatttc ttactgggat tggcggaatc tctcgaaaac gcgcatctgc
     7981 gcttcgtatg acatctcttg catcatcttg ccgattcgta tgttttccta atatatattc
     8041 gtaaaaaact tcatctacag gttccgtatg gagcaagact gtctgttctt tttggaaaga
     8101 agcaaattgc tcctgaacgt gttctgacag acctgcatct ccgatataaa caatatccgt
     8161 gttacttgct aatagatcaa gagcacctgc cagaggatgg atccctcgat gttcttccaa
     8221 agttggtaat ccttgataca gtggacctct caactctgta tctcctggta caaagccttg
     8281 tacaaggaat ccttgagttt tgagccattg atttttttcc tgataccatt ctttgtccaa
     8341 ccctgtttca agacgtggat aataattatg ccaagcttca atctgtgaga aatcagccgc
     8401 tgcttctttc aactcatcga tatcattagg cgtgatcgtg ctggcattca aactgatttt
     8461 caattgatgt gaccagtcgg cgatctgctg attagaaata tgataatcca ttcttaaccc
     8521 tgttacacca attgctttca agggtgttag atcttctaat gaaaagccag ctcgtttcaa
     8581 tgcctctcct gaaatatcga ccatcaactc tagtttattc tttttcgctt cgcttcctag
     8641 ttcgatcaat cgattttgat aagccgaaac atcatcttcc ggtatatgca tggaagtgaa
     8701 aataccgaca aagccattgg atgccatttg gcggatatac tgtttcttct cttctgacaa
     8761 agaatcattc ataaatattg aaaagccaaa catattatcc ctctttttct gtatccgtct
     8821 tcatttctat gactagagta tatatctaaa gaaacaaaat ttcaatactt ttgttaaaat
     8881 aattaaattt tatttctaaa aattggattt ataatgccaa aagaattgac acagccacaa
     8941 aaaaggcact gctaagcaaa agcagtgcct tgaaacattt tatttaaata acacaaaagt
     9001 ctaattactc ataagaaatt aattctgtat tgtctaccat gaatgtaaag aacccttcat
     9061 taggcattgg atgaaaataa gcattgatca ctcttatcaa ggcattatga cagactaaca
     9121 agtagacatt ttcttcgtct tccatgcatt ctttcaataa aggaacgatc cgtgcgtaca
     9181 catctaagac cgactctcca tttgggaaac gtacagcaaa cgctaaacgc gctttttgaa
     9241 agttttcatc tttgcttggc agtccgtcat aatccccaaa atccatttct accaatcgct
     9301 catcagcggt catcggcaaa ttgagacgat caactactgc ttgtgctgta tctcttgctc
     9361 gttgaagagg ggaatggatg attttcgtga ttggaacagg caaatctact accttttctg
     9421 ctagtgcctg tgcctgcatc tgtccttttt cagtcagcgg cacatctgct cgcccgcaaa
     9481 ctaatccttg tgcgttccaa gttgtttctc cgtgtctcgt tacataaagc atgtgattct
     9541 ctccttcgtt gacaaagttc tccttaacca taccttgttg tctttgagat tacaaggttt
     9601 agattttctc aagagaaata atctcagtag atactttatc tagaaaggtt tgatcatgtt
     9661 ccactagtaa catagcaggt ttcacgttca aaatcagttg ttctaattgt tcttgattga
     9721 agacatccaa ataattcaat ggttcatccc atatatagag ctcagctggt tgggataaag
     9781 atttagccaa ttccactttt ttccgttgtc ccatactcat ctgttcgatt ttattatgaa
     9841 aaacatctct ttccatccca agctttcgga gattattcaa aaatgcttga tagtctactc
     9901 ggtttttctt cgcgaattcc gccaatgtcc ctcgattgtc ttcataattt tggcgtacgt
     9961 aactaatggt caaatgtttg ggctgggatt tttctcctac aaccttgccg ttgaatgtcc
    10021 ccagaagata atggataatg gatgactttc ccgcgccgtt aggacctgaa attgccatcc
    10081 gctgatgagg ttcgatcgta aaatgaactg gctcgaataa cagattttca taccctaatt
    10141 gaagattttc tacgcttaac agccgtttat gatgagacac ttggctattc atcgtcaaag
    10201 catcgatata ctcgatatct tttaataatt tttctttctc actgatctgg gtttccatcc
    10261 gattcacgat tgctttagat cgtttcatcg tccgtgcagc atcagcgcct actgctcctt
    10321 tattcactcg cctagattcc gtatcgatga atccgacttt tttctttgtt ttgtcccctt
    10381 ctcgggaacg agaccattct gctttttcag ctgctgtttt ctttagcctg ctgacttctt
    10441 ttttcaattt ttcattttta gctatttcaa attcatcacg aagttttttc tgttcttcat
    10501 agatagagaa attcccttga taaagttcca gttggctctt ttcgattgct aaaacatggt
    10561 ccactacttc atcgataaat ccccgatcat gactcaccac gatgaatcct tgttttttct
    10621 ttttcaagta agccgctact tgttttctgc cagagatatc caaatgattc gttggttcat
    10681 cgattaacgg gaaatgagtg tcatccacaa ataagagtgc cagtaggact tttgtcttct
    10741 ctcctcctga tagtgtgctg aattctctcc ataagatttc aggatctgtt tgcatcagtt
    10801 ggagctctct ttcaatttcc catatctcaa aatccataat ctcatttaac acataatagg
    10861 tcaaacgctc tttatctttt gtttgctgcg ggaaatagac aaacgcttgc tgatggatca
    10921 cttgcccttg ataagggagt ttgttttgca ggatattcag taaagttgtc tttcctcgac
    10981 cgtttcgtcc gataagtcct agtttccatt gtgtgtcaaa gtttagattg gcttgttcaa
    11041 ataataatgt gccttggctg tcatagccga atgtcagatt ttttatttcg attttagaca
    11101 ttattccatc acctcgtaaa aaaagaccag tcctattttc agaactggct aaagaggatg
    11161 caagggttgg ggcacacaaa aagacccata catcgaaaga accaagccaa tcccgaaaat
    11221 ctgcacactg ctcccttgtc tccacaaggt acagtctgaa tgcagctttc atcaatcgac
    11281 ttaatttttc aatgcacgga tccctcactt tgtcctatat ttgaaattac gatagcataa
    11341 agaaattgtt tttgtcaact acttcgggag aatgttgaaa aatctgctga gtgtctgtcc
    11401 taagatttct gttttttcta atgtttgcct gtgttccatt gcttcctcta aatcgattgg
    11461 tcctaattga atgcttaaga caatggggag aaaatcaaag agtccttcca gctctcggtc
    11521 tctacttccg caaatagcga ttattggttt tcgatatttt tttgcaagca ctgctacgcc
    11581 atatggaact tttccgtgga ttgtttgctg atcaatccgc ccttctcctg taatgatgac
    11641 atccgcttgt tcgatctgtt tttctaatcc agtgatttgg ctgaccaact caaaaccaga
    11701 gaccatcttc gctcctaaca aaaaaagggc tccgccaata ccgcctgctg ctccgcttcc
    11761 tgggatgtca tctaaatcca cctcccaaac atcttttatc tgctgagcaa tcttttcagc
    11821 ttgtttatcc aagaaagcta acgtcgtatc cgttcctcct ttttgtcttc caaattgcca
    11881 agcagctcct tgttgacctg tatatgggtt ggtcacgtct gcagcgatga tcacttttac
    11941 tttagaaaca agaacgttcc ttcgatccaa atgaagtttt ctagtagata acaaaggatt
    12001 tccttctgtg tacccttcta aagaagcacc caaagattgg agtaatccta gaccaccatc
    12061 gctacatccg cttcctccta aagtgacaat gatttgttcc acttcttgaa gcagtgtatc
    12121 tttgataagc tctcccaagg cataactaga agcaagtcgg atggtttgat ccgttggttt
    12181 atcaagtaaa tctaatccta atacttgtgc agattcaatg actgcggtat tttttccttg
    12241 ccagttcgtc aataaataac tgatttttcg ctgacgaaat aagagatcca tcccatcaat
    12301 cgtacgccag gttcccccga gcgcgtaata gattgcttct gcagtatttt ctccgccatc
    12361 tgcaatcggc acattgattt ttcttccttt acggtcttcc caaccattta gaactgcctg
    12421 atttaattca aatgaagaag cacttccttt aaatgaatcg attgccgcca aaatatccat
    12481 ctatatccct cactttcttc ttaagtaaga cacttttttt cacttttttc aaacaaaaca
    12541 atgctatttt cttctgtttt tctatatact aaaagggaac tcattgaata aaggagagaa
    12601 aaaacatgaa aatcgcaata gctggagccg gagcaatggg cagccgaatc ggattaatgt
    12661 tgcatcaaag cggaaatgag gtcgtcttga tcgatcgctg gcctgctcac attgaagcca
    12721 ttcgtacaaa tggattgatt gctgacttta atggcaaaga agtagttgca aaactgccaa
    12781 tctattcacc agaagaaatc atcgaaagca acaaacacgt ggatttgatc gtagccttga
    12841 caaaagcgaa tcaattagat gatatgtttc gttcgatcca atccattatt actgagaata
    12901 cttatgtttt gtgtttactg aatggattag gtcatgaaga tgtactggaa aaatatgtac
    12961 caaagaaaaa tatcttattt gggatcacga tgtggacagc tggtctagct ggtcccggaa
    13021 aagtcacatt attaggtgat ggagaaatcg aactagagaa cttggaacca gaaggcgaag
    13081 catttacaaa aaaagttgta gaagtctttc aagaagcaaa attgaatcca atctatagtc
    13141 ataatgttcg ttattccatt tggcgaaaag cttgtgtaaa cggaacatta aatggattat
    13201 gcacgatatt ggattgtaat attgctgaat taggtgcgca aaaagcggca gagggcatgg
    13261 ttcgaacgat tgtatctgag tttgcttcta tcgcagcaaa agaaggaatc acattagatc
    13321 aagaagaagt gtaccaacat attgcttcta cttatgatcc tgacaacatc gggttgcatt
    13381 acccatctat gtaccaagac ctgatcaaaa accatcgttt gactgaaatc gactacatca
    13441 atggtgccgt ttggcgaaaa ggacaaaaat atgatattgc tacaccatat tgtgcctttt
    13501 tgacccaatt agtccatgca aaagaaggaa tccttggcgc agaataaaag gctctctgat
    13561 gagaatcagc tggatcagca gctggttctc atttttttac ccccatgaaa gttcaaaaag
    13621 aaaaacacaa ttctcatgtt gccataagaa ttgcgcttgt ttattttcat ctatgattgg
    13681 ttggcacttt tatttatttt taacagagga aagatcgtat tcatattgtt cataaatagc
    13741 ggagtcagta gtgaaaaaac gttttgccca attttctgca tcaaaaaatt ccaacagttc
    13801 tgatgggatt ggttgaaatg gcgtatgcaa aaattccggt aattcatcta aatcacgttc
    13861 ttgaagcaaa aaaatatttt cagaatgata aaactgataa tgagctatgg cttgattatc
    13921 tgtcactagt ttcttttgaa aatacataga ttcaaacgtt cgcaaagtca ctccttgctg
    13981 cccttcccgc aacagttcta gaatccccct cgattccccg gtttttttca gatattcttc
    14041 ataagtaagg tatccaggtt gttcatttcc tcgaagcgga agaataaagt aattggtcgt
    14101 aacacctctt tttgtaaatt cctgcttata tttttctgcc cgttcttttc tgccgttatt
    14161 tgttgcacca aaaaatagat ccgtctttgg ttcgctagaa gaaaaatcca tatgtttcga
    14221 ataaaaggaa ctattatgtt ttagtccaag ttctttcgct tctaaaaaat caaaatgata
    14281 aatctcatcg attgccggtt catcttgtgc ctgcttcagc atcgcctcgt gttctgcttt
    14341 aaagtggttc caaaaaaata acacgatttt tgcattggta aatggacgca cgcgtcgagc
    14401 catctccata tcaaatccat aatctaaaaa aacgatcagc tgataatttg ccaactgttg
    14461 tcgagctgat ttaatgaatt ccgactgtag taaatctttt ccggaccaaa catctaaaga
    14521 gcggatggaa ggaaaaaaat aaagtgattt atttttcgca attagcaata cgtcgttttt
    14581 gttcatctgt tccgcctcac tttctctgtc actttttcct atgatagcct gtttaaatag
    14641 taaaaagcca gtaaaacgct tcctattatt tttataaaaa tttaacattt ctatgaaaat
    14701 acgatgaaat aaatcattct tccattaaaa tatgcccaaa agttttctga atagttgtaa
    14761 ttatctgaaa atttgttatc attagtcatt attattatta ctatttattc ttactattta
    14821 ttcttactat gcattttgat tgtgaattta aaagaaagag gttatttatg gaagataaaa
    14881 aattgaaaaa acaacttagc tcccgacata tcaccatgct agctttaggt ggagcgattg
    14941 gtgcaggtct atttaaagga agtggcgaag cgattggaat cgccggccct tctgtattga
    15001 tcgctttttt gattggcggc ataattttat atatcgtgat gaaaggtctg ggaaaaattg
    15061 ttttaagtgg tggtgatacg caccacggat tatctggatt gattcgtcca tatctaggtg
    15121 ctcatgctgc cgattttacc gattgggtct actggtccat gtggattatc aatatcattg
    15181 ctgaagctgt tgcagctgct tcctttttac agttgtggtt cccccacatc ccagcttggg
    15241 tatttgtttt tatgttggct gttttaacta ctatcatcaa tctttattcg gtacgattat
    15301 tcgcagagac agaatattgg ctggcctttg ctaaaatcag tgtcattatc ctattgatca
    15361 tttttgctgc ttatcttgtc ggtcagcaaa tgttgggtac tggtgttttc cctacccttc
    15421 aacaattaac tgatcatggt ggttttactc cccacggtat gaagggaatc atcagttctt
    15481 tgcttgtagt tatctattct tacggcggtt ctgagttgat tgctatcaca gtaagcgaag
    15541 cagatgatcc taaacgtgcg attcctaaag caatcaaagg cgtcatggga agaatcattt
    15601 ccttttacat tattccttta tttttgcttt tgattatttt tccttggaat actttagcag
    15661 gcacgaacgt tagtcctttt gtgatggtat ttgaaaaaat gaatattcca tttgcggcag
    15721 atatcgtcaa tttcgtgatt gttcttgctc tgttctcgtc tatcaattca ggtgtatatg
    15781 cttcttcgag aattttgttc ttccgcttga aagatcggaa aggttcctct agaaaactag
    15841 ctgttttaaa caagcatcaa gtaccgcaac gtgctgtgct gttttgtacc agtgttcttt
    15901 atctaggtgt ggctctttct tattttgtcg gtgacaaatt atttggctat ctggcaggtt
    15961 ctctttccta tacagtatta ttgatctgga tcattatcag tgctgcgtcc tttgtactga
    16021 cactaaggaa aggaacgtta tgggacaaag gaatcagctt ttttgcatta gcagtcttat
    16081 ggttgatttt ccttggtatc ctattcacga actccattgg ggtaactgta ttgaccggtt
    16141 tgctttacct gttcatttat ttcagttatc aaaaaaagaa tgatgctttc gtcttgacga
    16201 atgaatgaaa ccaatagaga attttattct atttatattg aatatctgga gctattgaaa
    16261 aaaaggagct gcgacaaaaa ttgttgcagt tcttttttcc gaataaacgg tgttcaaaaa
    16321 ccatctgtgc agattaattg attgttctcc acgctcatga catgatagaa gaaaggaatg
    16381 aagaaaaagg agtttgtttt aaatgaaaaa gtattggaag tttttgttga tgattggtgt
    16441 ttcgacggta gtcatgtttg gtatgatgta tttgaatgtt tatgcgcttg atcatatctt
    16501 cttcagtcgc acacgtgtat tcatggcgtt gatgatgggt gcagtcatgg cagtcatcat
    16561 gttgttgttc atgtggaaaa tgtatgaaaa caaaaagata aatgctatga ttttagccgc
    16621 tagtcttctt gtttttgccg gttccttatt tatggtacga agccaaacaa ctgtcaacga
    16681 tacggcgtgg atgaaggcga tgatccctca tcactctatt gctatcttga caagtaaacg
    16741 agctgattta aaagatcctg aagtaaaaaa attagcggaa gaaatcattc aggcacaaga
    16801 agaagaaatc gacaaaatga aaaaaatgat caaagaaatg gaatgaccat tatccatcca
    16861 aataaaaaaa gaggatgttc cagaagtgat caacttcaag aaataagaag aagctacttc
    16921 tggaacaccg tgaatcagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    16981 caaacaaaaa tagcttctca tatttttcgt ttggttaggc ttattaccgc aaatgcaagc
    17041 ttttgaacac cgtttattcg taaaagggag tgtgacaaaa gtcttgtcac actccctttt
    17101 tacgttttta ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt
    17161 tctttgagat cccccaacct gtaaaggcac tgaccatcga aaacacaggt gaaagcaaac
    17221 tgaaaaacac gaatggcaag taagtgagtg taggaatgcc aaatgtactt gctacgaaac
    17281 ttccggcgat tccccaaggc actaagtagt tgattactgt tccaccatct tctagtgttc
    17341 tccctaatac agttggatca aatcctgctt tttcgtaagt ttctttaaat gcattaccag
    17401 gcaggataac agatagaaat tgttctccaa taaagatatt tactccgatg cttgtcatca
    17461 atgttgtaaa aatcaatttt ggggtgttcg tcatctttct tgatactcgt tccataacgg
    17521 ttgagatcaa cccaaattcg atcaacaaac cacctaatga caatgttaga ataatcaatg
    17581 acacagttgg catcatgctt tcgattcctc cacggctaag tagtgaatcg atttgttggt
    17641 ttccagtatt tgaaacaaat cccgattcga tgacccctgc caacttcgtt aaggaagttt
    17701 gtgggttttg aataaagatc attcctactg ctacagcaat attcaacaaa atcgtcaaaa
    17761 ttgccggtac ctttttccat gcacacaaga gcattaaaaa tagaggaatc agtgaccaga
    17821 tcgaaatagt aaagtttgct tctaaaatat cagtcacttc acgaatagat gaaagacttg
    17881 cggctttact tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggaa
    17941 cagttgacca catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg
    18001 ctaaatttgt tgattcggat aatggagaca tcttgtctcc aaaaacggca cctgaaacaa
    18061 tggctccaac aacaagggct ggatttagtc ctagtgttgt cccaataccg aaaaatgcaa
    18121 tcccaatcgt tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaaa
    18181 caacaaatac agaagggacg aaccactgga cactaatcaa tttaaatcca atgaccatga
    18241 gggttggaat aattcctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa
    18301 taaagattgg aatgatcccc ggtttgatgc cattgatgat cccttcgtgc agccaatctg
    18361 tcgggtattt ttttatcact gcgtacaaca tgaccattcc gatagctgcc aaaatcgtga
    18421 tattaggtga aacctttaat ccgacaacgc caatcgcaat gcctaaaaca atgaccatca
    18481 atacaagtgt tgcttctaaa aaacttggtg ttcctttttt tccatgataa tctctccttt
    18541 tttagttgtt cttatgttct aaaaaagtta agatatcgga ttactccgcc acaattcatc
    18601 cgcgattcct cctttataaa aataaaaaga cctgctttca actaaggacg aatgactccg
    18661 cggtaccacc ttaattaaaa acagatctgt ttttcacttt caaacgatta ttcaaatgta
    18721 tggactttcc atgtaattcg tcaattaggc ttgatcggtt cacagcgacc accgactttc
    18781 tgaacaaaac acctaaccac tactgcgtga aaagttgact tgtatgaagt ttaccttcca
    18841 taagatcatt tgtcaatgaa aaagaaaata ttttttcatt tttctgaaaa ttatttttat
    18901 aactttcgcg cacaacttta tctttttact agaaagtagc gccctcttgt ttttttcttg
    18961 ctactatttc ttgatgttct tgtttgattt tttctaatag cttgggttct ctcaataaat
    19021 ctagagctgt attggcaagt aattccgctg caatcgcaat agaagcaagt cctttttcac
    19081 ttttagcagc agctttgaat tcttctgtat gtccggcaat atatgtctca gagattgcta
    19141 cagtaggctg tatcgttgga ataacttggc taacatttcc tacatcagaa gaacctagac
    19201 ttgttctttg ttccgtttct atttcttcat caggaacccc tgcttctttt gcatgttgga
    19261 agaataagtc atcgaaagaa ggcgttacga tgacatcatc gactgcattt tggaacaatc
    19321 caaactcaaa agtcgtaccc gtgcttaatg cagcacctcg tacgatattt tccacttttt
    19381 catatacttt gtctaatgtt tgtcgatttc ctgcacgtaa atagaaacgt ccagcagcgt
    19441 agtctggtat gacattggcc gccacgcctc catctgtaat gattccatgg atattgacat
    19501 cttttggcaa ttgcaagcgt agagcgttga ttccgttaaa cacttggatc aaggcttcca
    19561 aagcatttac tcctttttca ggtgctgctg ctgcatgaga agcgacaccg taaaatttga
    19621 tatcgactgg atcatttgct aaagattctg tcgttttccc ataacgaaaa gctggatgga
    19681 cacataatgc tgcatcgaca tcctcaaaaa aaccttcccg aacgaagctt cccttagctg
    19741 atccattttc gcctccttct tcccccggag taccatacac acgaatttct ccgccaatct
    19801 catcaatgaa ttgtttcact atgctggctg ctaatacgga gtaagtacca aataaattat
    19861 gtccgcatgc atgaccaata cctggtaaag catcaaattc tgccaaaaag gcaattgtcg
    19921 gacctggttt attggaaata taacgtgcat caaagcctgt tcggtgccca gctacttctt
    19981 tttctaccca gaacccttct ttttccaatt gtttgattaa agctgctgag gaataaaatt
    20041 cataattact tacttcagga tggtcgtgga tagctagtgc aagtgcttga tattctggta
    20101 aacggtattg aatcagatcc ttcaattgat ttgttgagag tgtggttgtc ataaaaattt
    20161 cctcctatgc tagtcgtttt ttcttatttt ctcccgaatg tttcccacgc aggtacgctt
    20221 gaaccttttg atgttttttc gattactttg gctgtttctt ctgtttgata ggcatctact
    20281 attttttgat acgttttatt gtcttcatct tcttttcttg caacgatgat attgacataa
    20341 ggacgtgcat gctcatcgac tggttctaag aagattgcat cagaagcggg attaaatcca
    20401 gcatctacag ctacaccgct attgatgact gaaatatcta catctgacaa agcacgtgct
    20461 gtttgggaag catctaactc agaaatgtct agattttttt tattctcggt aatatcagaa
    20521 acggtaggcg cttggccttt tgccttgtcc actttgatca atccagcagt ttgcaataac
    20581 agaagagctc tgccgccatt cgtgacatca ttagggattg caacttttgc tccatctttg
    20641 atatcagcca catcttttaa cgtattggaa taaattccca acggtgcatt aaccgtattc
    20701 ccaatcgata ctaaatcagt tccgtgttct tcattgtaat tgtctaaaaa gaattgatgt
    20761 tggaaggaat tcaaatcgat cgatccatct gctaaagccg catttggctg attgtaatct
    20821 gtaaatttca catattccaa atggatgttt tcctttttca aacggtcttt cacatcgtcc
    20881 catacatctg tatcttcccc aatgatccct agttttacgg tcgtttcttt tttttcagtt
    20941 gtagctgctt ttccttggct gcatcctgcc aaccaaataa ttgctacaaa tgtaatgact
    21001 gcaaaacgaa taattttttt cattttttct cctccatttt caatgtgtga cttttttaat
    21061 cagttgatta ctgataaatt gactcaaaaa aactaagacc agaatcaata atgtagcgac
    21121 aatcgttaca tctgtttgga atcgattata tcctctcgat atagcaagat tccctaatcc
    21181 tccggcacct actgctccag ccatggtagt cagtccgatc acattgatga tcgtcaacgc
    21241 tgagacccga atgataccag gtaacccttc taacaaataa acacgtaaaa tgatgccgat
    21301 tgggctcgtg cccatcgctt ctgctgcttc gatcacccca ggatcaactt ctagcagtgc
    21361 attctcgatt tgacgggcaa aaaacgggac aacgccaaaa atcaaaggga ctaaagctgc
    21421 tttggcacca atcgtcgttc caactaagaa acgagtagtc aaagctaaaa gagaaagcaa
    21481 gataatgaaa gggatggaac gaatgatatt gatcaactta tcaagtattt cgaacagcag
    21541 cctgttagct agtaatccat ttggacgtgt cactactaac gtcacaccta agatgattcc
    21601 gatgatccca ccaatgaatg ccgtccaaaa agacatatat agtgtttgct ttgtcgcttc
    21661 gatgaattca tccggaatca aatagacatt cggcaaatat gttttaaaaa attcagtcat
    21721 tttagtttcc tccttcgatg actttgatac ggttatctaa ttcatttttt tgtaaaatag
    21781 ttacttttac accagattta atcaaataat ccaatgcttt ttgccgctgt ttggtttctc
    21841 cagctaaagt aacgatcaaa cttcctaagg gtgtttcttg taatagctct acattaccgt
    21901 ataagatatt cgctgttact tggtacttgc tgtaaagatg agcgattaga ggttcgttcg
    21961 tctggttgcc gatataactt aattccacca accatttatt tgcaatctga tcggcaaaag
    22021 cagcatgggc actgattgtt tccaatgctt ggtcaaggtg tgtcgctgtc cgaataaaat
    22081 ctttagtcaa ttcttcttca ggatgactga aaatctggat gctgctacct ttttcaatga
    22141 ttttccccgc ttccataacc gctaccttgt tgcagatttc tttgacaact tgcatctcat
    22201 gagtgatcag gacgattgtt agacctagct gacgatttag tttttttaac agtgcaagga
    22261 tctgaagggt cgttttcgga tcaagtgcac tagttgcttc atcgcataac aacactttag
    22321 gttcatttgc cagagctcgt gcgattgcca ctcgttgttt ttgccccccc gacagttgtt
    22381 taggatacgc agatgctttt tcttccagac cgacaagttc cagtagttca ttcacttttt
    22441 gacgacgttc ctgttttgat tttccagaat actttagaga aaaatctacg ttgtcaaaaa
    22501 tcgttcgact ttccattaga ttgaaatgct gaaagatcat accgatggcc tttctttctt
    22561 ttcgcaattc ttttggagag agctggctta aattcgtctg attgacgatg acttctcctg
    22621 ctgttggttt ctgcaacaaa ttcatcacgc ggactaacgt actctttcct gcacctgagt
    22681 aaccgacgat cccataaaca tccccttttt caatcgttaa atctacagaa tctactgcct
    22741 gtatctcttt ttctttttgt ttgaaacata cagaaatatc tcgcaattca atcattaaca
    22801 ttcctccttg tctataaaaa aagcatcctc aagaaaatga aaatagtcat tttcttgagg
    22861 acgccttttt gcgtgttacc acctcatgtt caagctgtgt tcacacacaa ctcctcttca
    22921 agtaccatca tactctagca agatatcggt cgcagccgtc accgccttac atctatgctc
    22981 gggatgaatt gctcgatggc cattttccaa tagtcgttcc ttgcttcttc tcagctaccg
    23041 aagctctctg tcaaaggttc ttctatcgta cttaccattt caatgcaaat aatattcaaa
    23101 aaaaaaatcc ttttactaac ataaactatg tcagtaaaag gacgacgtat cgtggtacca
    23161 ccttttttcg gaagtttcct tccctcaagc ccaacatctc aaaaagagag attggcgttc
    23221 gttttaacgg tcgaacattt ccgaatttgc ctacttatcg acaaattatt ctccaaggcc
    23281 attttcagct tttcttactt gactcttcac accagccaga gcctctctgc aaagtttcca
    23341 agcttacttt ccttctcaac gaaatcaata ttttgttgtt gggaataatc tacaggagga
    23401 aaactgaaaa gtcaagcatg aaatccaaat tattttttct atatttattt ttctgttttt
    23461 ttatctaaca tttcaataac agttcgaaga tcttttcctt ccgcaagaag gttcaatttt
    23521 tccttctctt cgacgctata atttcgaaca aaactggaat cgggaatcaa aacaacgcct
    23581 agtcctgcac gtgaagcggc tgtcgctcct actaaagaat cttccactgc aaaagctgaa
    23641 agagcttcta atcctgttcg ttccaaagct gtcagataag ggactggtga aggcttgttc
    23701 tccgatactt catctccgaa cgtaaacgta tcaaagtaat cggctaattg aaagtgatcc
    23761 aagatatctg ttgctctttt cgtaacagtt gtcgtagcaa tccctagttt catatgacgt
    23821 tcttttaagt ctgtcaatat ttcttttgca tagggtttca attggatagc tccacttgtc
    23881 agctgttgat aaaaatattc ttcacgcttt gctcggactt cctgcacttt ttcaggactg
    23941 cctgctgcct gcactaaaat atcaaaactt tgtttccagt tttttccgcc ccaagcgtca
    24001 acgatttctt tcgggatatg aatatcaaat tgctggaatc cccaaagcca accatcccga
    24061 tacgttcttt ccgtatccac taacaaacca tctaaatcaa atattgcacc tttcatctat
    24121 acattaatcc tttccaaaac aatacaccta gtttagcatg actgatccaa aatgaacaga
    24181 agcatagagc ccagccgcat cacttataag agttcttgga atcgacggat atagattttc
    24241 ttcacagctg tcacaagcgc cagataagcg acgactgtta taaacaacca taaccagtaa
    24301 ttgccaggga gcggcatcaa gcctaactca gcaccaaatc ctgtgaatgg aaggactgaa
    24361 ccgacaatga ttcctaatgt agtgataacc agcatggcaa atgttgcatt gctttggata
    24421 aatggtattt tcggtgtacg caatgcatgg agtactaatg tttgtgtcca cagggattcg
    24481 acaaaccatc ctgcatggaa taatgcgata aaaatcactt gttgtgagct atccaatgta
    24541 tggaaacttc caccaactac agcaggacaa ataacaaaat acatcaacaa gtaagtagtg
    24601 atatcaaaaa tcgaacttgt tggaccaaaa taaaccatga attttccaat actagatgca
    24661 ttccatttct ttggctcatc caaatattct ttatccatcc gatcccatgg taaggaaatg
    24721 caagaaacgt catagatcag attcaaaaat agaagttgca aaggcaacat tggtaaaaat
    24781 ggtaagaacg tactggcaat cagtacggaa aacatattgc caaaattaga acttgctgtt
    24841 gccttgatat atttcatgat gtttccaaaa gtttctcttc cagaaagaag gcctctttcc
    24901 aaaatcgtca aatctttttc taaaaggatc acgtctgctg attcttttgc gatatccaca
    24961 gctgtatcca cggaaatacc gatatcagcc actttcattg ctggagcatc attgatacca
    25021 tctcctaaaa atccgacagt atgcccattt ttacgtaaag ctgtcgtcaa tcgtgctttt
    25081 tgctgaggat tcaattttac gaatacttcg tgttcttcag ctacttgcgc taattcatga
    25141 tcattcattt ccgagatttt ctcaccagta atcaattcat tgatttctag gcctacttga
    25201 cggcacacag accgtgtgac taattcattg tccccagtca gaacttttac agctacacca
    25261 tgttctttta aagctttcaa cgcttgtttt gttgtttctt ttggtggatc aaggaaagca
    25321 agataaccaa tcagaaccat gtctgactca tctttgactg aaaattctcc aacaacgctt
    25381 ggattggtct tttgtgcgac accaatcact cgtaagccgt cttcattaag tgattgtact
    25441 tttgcaagca ccgcttcttt tcgttctttt gttaatggtg cgacagtacc accaagatca
    25501 ataaatttag aaatgttcaa catttcttca atcgcgcctt ttgtgatcat ctgtgttttg
    25561 ccagccggat cagcgactac aacactcata cggcgacgtt caaaatcaaa aggaatttca
    25621 tctacttttt gataattgat tgtatctgta tctaaagttt ctgctgcttc atcaatgata
    25681 gccacatcta acaaattttt cagccctgtt tgatagtagc tgtttagata agcatggcgc
    25741 aaaacacgat catcttcatt tccttcacaa tccatatgat attcaagaat gattttgtct
    25801 tgtgtcaatg ttcccgtttt atccgtacat aacacatcga tcgcaccaaa attctggata
    25861 gcatttaaat ttttgatgac tgttcctttt ttggccatca cacttgctcc tttgaccaaa
    25921 ttcgtcgtaa cgatcattgg aagcatttca ggcgttaaac caactgccac agataatcca
    25981 aaaagaaaag cttctaacca atctcctttt gtaagcccat tgataacgat aactgctgga
    26041 gccatcaatg acataaattt gatcagcagc atggatgttt tgtggatgcc taattcaaaa
    26101 cttgattgga tgggtttttc agatagcgtt tctgctacat gcccaaatag tgtgtcattt
    26161 ccgacagaaa caatgattcc ttccgcgctt ccactgatga cattgcttcc cataaagaca
    26221 agattttcat aacttgtttc actttgctga tcgtcttcac atactttcgc atgcttttct
    26281 actggatagc tttcccctgt caatgctgct tgagaaatga atagatcctt tgcggacaat
    26341 aaacgcatat ccgctggtat catatctcct gctgaaagcc gaacaagatc tccacagacg
    26401 atttcttcca taggaatctc tgtatactcg ccatttcgtt tgacagctgc cgttactttc
    26461 acaagtgatt tcagtttttc agctgcttga ttagaacgca cagactggat caacgtcatc
    26521 gtcccactga cgataaccat agtgaagata atggctacac caaagagatc tttatctcct
    26581 ggagcggcta atacgtattc cgtaatgaat gaaataattc ctaatgcaat caacactaat
    26641 gtaaagggtg tgatgtatgc tttcaatatt tctataatga atggtgtttt tttgccatat
    26701 gaaatcgcat tttcaccata agtttctctt gaacgctcga tttgttcttc tgacaatcca
    26761 tttggtgatg catggaacaa ttcaaataat tcttgcttcg tttttccagc aaaagctgca
    26821 tagatttttt gtgtatcttt ctttttttcc atctcgatct ctcctttgtg tccaaaagac
    26881 agctgttctc gctgtttttg gtcttttgct attcatcgga tcgatagaga aaatgctgaa
    26941 aggggctgag aacagataga taatagccct ggcctttcct ctaaatcctt gtttttcgaa
    27001 tgactgtcat ccatttgttc tcatctcctt tactaagtaa ttttaattca tgacttccaa
    27061 tcatttttcg aatagttatt ttcccaactc gctcacctcc ctttttgttt tttcacctat
    27121 gggatttgcg gcaacaaaaa aacctctcgc caaatactca gcgaaaggtt tgaaaaagca
    27181 aatcaaaaaa agcttctcag atctcatcgt tgagttttga cactgtacaa cgtaaaaagc
    27241 agatatctgc ttttagctac cttatgaaaa gccttatctc gacaattcct gttctaccca
    27301 ttggcgtctc tcgacgtttt tgggcagtag cctatgtttg tataggagcc tcacctaaca
    27361 aatcctattc ggttttccct cgttaatata acaactaaaa aagaggatgt caaatcaatt
    27421 ttccatgttt ttcatacttt tttaaaatac acgcgttata tttcctgtct cacgcagttt
    27481 tatttgtctc attttccacc tcccgctata atagaattat agtaggaaac gaggtgctgt
    27541 tatggaacga acacttgtta ttatcaagcc agacggcgta agacgccatt tggtcggaag
    27601 catcatccaa cgttttgaag caaagggact ggccattgct gaaatgaaat ttgcaacgat
    27661 gacacctgaa ctagcaaaag aacattatca gcacttgact gaacgtagtt tttttgatga
    27721 gcttatcgat tacatgactt ctggtccggt cgtttatctt gtgctggtcg gcgaggaagt
    27781 gatcgatatc gtccgtaaga tggtcggagc aacaaaaggg gcggatgccg ttccaggtac
    27841 gatccgagga gattatgcac tgccggggac tgaaaacatc atccatgctt ctgattcccg
    27901 tgatgctgca acaaaagaga tcgcccgctt tttcccgcca ttcgatacaa acaaaccgtc
    27961 tgaaaaagcg gcgaagtgat acaaatccta aactgttggt ctaactgctg ggtttagcaa
    28021 tggccagcag ttttttctct aaagaattcc tttgattctt ccctaatgta tattcgatca
    28081 ctgcgaaaaa ctcttggtga ttttccgatt tttcttcccc taaagcagca gaaatcagtc
    28141 gttggtaata atccgccatc aatgtttcat aaatcactgt acttctttct ttatgcgcta
    28201 aactccgttt catatcttca ttcacgctac gtgccttttt taagcgacca ttttctatat
    28261 aaaacaaagt caagttcgtc aaaaaagtaa agagatactg ctcgtgatta ttcagttgcg
    28321 cgatccgtcg cattcttttt ttgattttca aataattatt ctcaataaaa cgatcactga
    28381 atatccaagg aaaatctgct agaatagata cttcaaattg cccatactct ggtacttgca
    28441 tcaaatattc ttcaatgata cgacattcat aacgcaaaaa ttcaaattcc gtctcagata
    28501 cttctgtttt tttggacatg tgcagattca aaaccaaata gtacagatct tctgttttct
    28561 tatagtgcct gcggttatta gcaatttctt tgtaaggatc aaagctgtct tcttgaatcc
    28621 gatctagcat tcgtcttttt ttctttaatt tttttggctc atcaagctga tttcgtatcc
    28681 attcatattc ggcaagtgtc atgttcattc gctctaaaaa tgatttcaat gttccaaacg
    28741 atactttttt cactgaattt gtctcgatcc cgactagcga agttttagaa cagattcctt
    28801 ccgctaattg ggtctgtgtc agctttttgt tgactcgaag cttcttaatc aattctccat
    28861 catacataat agttctcctt ttttaattga aattaaccct tggcttttcc agaatgcttg
    28921 ccaataagag gaatgattat ttcaatttaa attttccgca ttcaataaat agatacgtta
    28981 aaaataaaaa atacacgaaa aaaataaaaa aatgtttttc tcataaaaaa taccaacctt
    29041 caagcatgag actgctgtct aatccctgaa ggttggtttg attgtttatt gatcattttt
    29101 ttactgctcc gcattggttc ctgttactgg atataggata gtcgttgttt tattgccgtt
    29161 ttttgaaaag acactggtcg aatgttcacc tttttgcttt tcgattgctt cattacgttc
    29221 cgcttcgttt ttatagtcat attttttcgg atcaatcgtc tcaaatccgt ttggcacata
    29281 aaaccgcaag agattttcct gattcagctt atctgaaaga cttaacgcag tcttgacttt
    29341 ttcctgatct ttggagattt cctcgtcgat tcctgctgct ttcgtatcga tgatttctcc
    29401 tgtctgatta ttgtaagctt ttcctcctag gacggtgtat ttgggcgtca cgaagttccc
    29461 atttcgaaaa gcaactactt gatcgtgctg agaagataat aagtctgtac caaaatgaag
    29521 ataatcttta tcatcgattc ccaatagatg tagtaatgtc ggcaaaacat cgatttctcc
    29581 accatattca tgattgactg tccctttagt gtaaccaggc atatggatca tcaatggcac
    29641 tcgttgcatc tgtgcgttgt caaattcatc ccatgtatct ggatctttac caagagcact
    29701 tgctaaatct ttattatctg tattcgagat cccaaaatga tccccgtaaa tcacaaagat
    29761 tgaattttgg taaataccag attttttcaa atacgtaaaa aattgttcca atgattgatc
    29821 cagataatgg gccgttcgaa cataattatc tactgtgcta ttgccagtat tcaaagatgg
    29881 aaagtcgaaa ttcttgtcat ccgtataata aggcgtgtgg ttggttacgg aaagaaattt
    29941 cgtgtaaaac ggctgttgta gatgttcaag atattgggca gattctctga ataaatcttt
    30001 atctaatatc ccataaccta acgtttcatc ggattcatca aaataagatc gatcaaagaa
    30061 attgtcatac cctaaatttt tatatacatg atctctattc cagaaactag ctacattccc
    30121 atggaaaaca gcacttgtat agccttctgt ttgaccaagg gtcgctggtg ctgcttgaaa
    30181 gacattatct gacccaagtt ctgtgaataa tgagccttga ggtaaaccaa atgtgccagt
    30241 ttccaacatg ttttcagcat cacttgtctt tccctgtcct acttcatgaa agaaattgtc
    30301 aaaactgatc gttgcttgat tctggaaaat actatttaaa aacggcgtga cttcttgtcc
    30361 gtctaccttc atattgatca aaaactgttg aaaactttct aaatgaagga caatcacatt
    30421 ttttccttta gcaatcccaa atgtttcagg atttggctct gcataatgtt tctttgtata
    30481 gtctaaaact tcatcaattc cattactgct tgcatgcgcg cgaacactgc tagtcattcc
    30541 tgttttgatt ccgtcataaa tagtgtacgc atcgattcct agatatttga caatatagga
    30601 acggtcaaat gtccgctgta gcaattgggg acggttggct tcgctcaacg ctaaatttcc
    30661 tgaaaaaatc aatcctgaaa gacaggtaac agcgatagcc atcggtttgc tgacagggtt
    30721 gcttttgata ggtattttct tgaccttcaa ccaaaccagt agcccaatga acacagcgat
    30781 atccaaccaa tagatgacat catggggttt catcaaagaa aaggagcttc ctgacaaccc
    30841 ttgtgacact ttcgaaaagc ctaatacaga tttgactgta atgaaatctg tgaattcccg
    30901 ataaaaaata atattcaagt acaacaaaag cgtatttaaa atatcaatga tcaaaagaat
    30961 ggctaacgct ggctttggct ttttaatata caaagaaagg ccaaaaaaca ataaggtagt
    31021 cgcaatcggg ttgatccaca agataaagta ctggatcgta ccttccacac ctaatgaaaa
    31081 atctgcatag taggcaatga tcgtcttcag ccagaaaaag aaaacagctg tcaaaacgat
    31141 tgctaaacga ttttggcaca attttttaag ttgtgtcacg tatatcactt ctctctattc
    31201 acattttttc ttattttgct cctgaaaaat gaaaatttcc taaaaaagtt gttatcttaa
    31261 gattttttta ttctttctaa agattattcc attcattttt cacagcataa aatcgtttcg
    31321 gtgtaagcgg ttaaaatagt aaggagataa aaatcttgtg gtgaccgatt tactctatag
    31381 tattcaaaag tagtttctcg gtattcgtac aaaaaaaaca tactaagatt agaggggaac
    31441 atcattgacg aatgatgttc tcctctattt tctattttta gattatagtg aagagtgaaa
    31501 gaaagttcga acaaagcctt gaggactacg agtccctatc aaaaaccgaa cttctttact
    31561 gtcattttag aatcaggttt acgtatgttg gggccatgag cccgtgtata ggaaattgga
    31621 atcgaaatga agcagtaaag ttctttcaac acttaaaaag gaggaaaaca aatgccttac
    31681 attcttgcat tagatgtttc aatgggacac agctacagtg tcctatacaa agacgacacc
    31741 tgcttatttg aagacgagat cgaacacact caaagaggat ttcatgcatt actcgaagag
    31801 atccagcact tgcctgaacg tccattgatt gtttttgaag caacgggtat ttattccaga
    31861 ccagtcgaaa agttctttca agatcatcac ttttcttact gtttgttaaa cccgttagaa
    31921 gcgaaaaaac agatggaaga aaacacctta cgcagttgga aaacagataa atcggatgcc
    31981 catcggctcg cacagactca tcttaaaaat caacgtcaac caaaagaagt acaaagcaat
    32041 ttttacttag agatgcgcga tttagcccgt ttttatcaag aaattgagaa gaaaatcact
    32101 cgactgcgca tggatttaca caactgcctt cagttgactt ttccagagct tgaacagttc
    32161 ttttcaaaca ggctgacccc ttacgcattg acattgatcc gtctttttcc ccatccagat
    32221 tttgtattgg catctactcg gacaaaaata aaaaataaac tgatcaacga aacacgggaa
    32281 aaaatctccg cgaatcgtgc cgagcaaaag gcagatcaaa tcatccacta tgcacagtgt
    32341 gcctatccag ctgttgaaaa agacagtatt cactgtcaaa aaacgatcta ttacgccgaa
    32401 cttctccaag atttactcga acaaaaaaaa gcactggcga cacaaatgat caaaaaagcc
    32461 gaag
//
LOCUS       DAKCAA010000030        29927 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000030 DAKCAA010000000
VERSION     DAKCAA010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.030"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            68..808
                     /locus_tag="OUE31_001493"
     CDS             68..808
                     /locus_tag="OUE31_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCU0222507.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1232..1402)
                     /locus_tag="OUE31_001494"
     CDS             complement(1232..1402)
                     /locus_tag="OUE31_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0222508.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1596..1775)
                     /locus_tag="OUE31_001495"
     CDS             complement(1596..1775)
                     /locus_tag="OUE31_001495"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222509.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            2162..3274
                     /locus_tag="OUE31_001496"
     CDS             2162..3274
                     /locus_tag="OUE31_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCU0222510.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3352..3645)
                     /locus_tag="OUE31_001497"
     CDS             complement(3352..3645)
                     /locus_tag="OUE31_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HCU0222511.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3813..4127
                     /locus_tag="OUE31_001498"
     CDS             3813..4127
                     /locus_tag="OUE31_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HCU0222512.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4148..6127
                     /locus_tag="OUE31_001499"
     CDS             4148..6127
                     /locus_tag="OUE31_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCU0222513.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6140..6466
                     /locus_tag="OUE31_001500"
     CDS             6140..6466
                     /locus_tag="OUE31_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HCU0222514.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6482..7000
                     /locus_tag="OUE31_001501"
     CDS             6482..7000
                     /locus_tag="OUE31_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222515.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7000..8352
                     /gene="celB"
                     /locus_tag="OUE31_001502"
     CDS             7000..8352
                     /gene="celB"
                     /locus_tag="OUE31_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCU0222516.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8436..9941)
                     /locus_tag="OUE31_001503"
     CDS             complement(8436..9941)
                     /locus_tag="OUE31_001503"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HCU0222517.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10033..10623)
                     /locus_tag="OUE31_001504"
     CDS             complement(10033..10623)
                     /locus_tag="OUE31_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCU0222518.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10802..12448
                     /locus_tag="OUE31_001505"
     CDS             10802..12448
                     /locus_tag="OUE31_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCU0222519.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12497..13216
                     /locus_tag="OUE31_001506"
     CDS             12497..13216
                     /locus_tag="OUE31_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCU0222520.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13695..14642
                     /locus_tag="OUE31_001507"
     CDS             13695..14642
                     /locus_tag="OUE31_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0222521.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14654..15574
                     /locus_tag="OUE31_001508"
     CDS             14654..15574
                     /locus_tag="OUE31_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCU0222522.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15615..17072
                     /locus_tag="OUE31_001509"
     CDS             15615..17072
                     /locus_tag="OUE31_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCU0222523.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17417..18031
                     /locus_tag="OUE31_001510"
     CDS             17417..18031
                     /locus_tag="OUE31_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCU0222524.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18024..19748
                     /locus_tag="OUE31_001511"
     CDS             18024..19748
                     /locus_tag="OUE31_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCU0222525.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19745..21196
                     /locus_tag="OUE31_001512"
     CDS             19745..21196
                     /locus_tag="OUE31_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0222526.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21669..23822)
                     /locus_tag="OUE31_001513"
     CDS             complement(21669..23822)
                     /locus_tag="OUE31_001513"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HCU0222527.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23824..24870)
                     /locus_tag="OUE31_001514"
     CDS             complement(23824..24870)
                     /locus_tag="OUE31_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0222528.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            25020..26309
                     /locus_tag="OUE31_001515"
     CDS             25020..26309
                     /locus_tag="OUE31_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HCU0222529.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26322..29024
                     /locus_tag="OUE31_001516"
     CDS             26322..29024
                     /locus_tag="OUE31_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HCU0222530.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            29009..29866
                     /locus_tag="OUE31_001517"
     CDS             29009..29866
                     /locus_tag="OUE31_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCU0222531.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
BASE COUNT         9724 a         5176 c         6098 g         8929 t
ORIGIN      
        1 ggggtatgaa ttagatgcga caccgatcga gtttgagatc gaaagaagtc agacagcggt
       61 ggtagaattg acgaaagcaa accgacttac accaggcggt gtcgtgttga caaagatcga
      121 tgaccaaagc ggggaagtcc tgcaaggagc tgtttttgag ttacaagatg ccaatggaac
      181 cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgattg acggcttagc
      241 accaggagtg tatcagctgg tagaaaccca agcgccaacg gggtatgaat tggatgcgac
      301 accaatcgag tttgagatcg aaagaagtca gacagcggtg gtagaattga cgaaagaaaa
      361 tcgacttaca ccaggcggtg tcgtgttgac aaagatcgat gaccaaagcg gagaagtcct
      421 gcaaggagct gtttttgagt tacaagatgc caatggaacc gttctgcagt caggtctaac
      481 cacaggagca gatggaaaac tggcgataga tggcttagca ccaggagcat atcagctggt
      541 agaaactcaa gcgccaacgg ggtatgaatt ggatgcgaca ccagtaactt tcaagatcga
      601 aaaagaacaa gaagtggcga tctttttaac aaaagagaat agaaaagttg ctgatagctc
      661 agatataaga ggaaacaatc caacaagcag tggaaataag catcttccaa aaactggaga
      721 aaccatcatt agccagttta tattgtcaat attgggtgtg ctacttgttt tcatcagtat
      781 aaaatttaga aagaaacgaa atatatgagc taaaataaaa aattgaataa gcatagtttt
      841 taaaatcaac tagtacccat caattgaatg gaaactaccg attttagaag gggtatacaa
      901 acaaatatta gtatcggagt agagaaggtt gaacccaacc agtaaataag taaagacaat
      961 tttgtgctgc gttgagaagt gaaaaataaa cctttgtagt aatactagtt aataaaaaat
     1021 atacaaaaac actgcgaaaa tcattcttga gtttcgcagt gttttttgcc taatgactca
     1081 agtttattgg gtaatacttt gattttcttt ctacaaataa tcagcgatca gttgtaattt
     1141 tttctctagt tttaatggct ctttgtcaat aaggagaaaa acaagtcggg tcttttgtct
     1201 cggaaagctt caaccaactc gtgaataaag gttacgcctc cttgaaaggc gtggaaaaac
     1261 caagtaatcg atcaatcacc aatttcgcat ttggtagaac atgtttggtg agctgaaagt
     1321 aggtggcgtt catgtctgta actaagaatt ctatttcttt aggattagtg cagctaagga
     1381 aatagtttgt taatcgagga attttttgtg taggtaaatt ttctcgatta atttttctgt
     1441 ctcgccatcc gcggaaataa aactcagttt atcctcaacg gaaacgtgag aacgaaattc
     1501 acaaccctca acactcaaga cagaattctt ttggaagact ttggtaaata gcttctcaac
     1561 tctttcaatg tgcgaataac ggttgtcaaa gatacctaac aacttttcga aataaaaaat
     1621 aacgacactt tttcagtcag taaagaagtg attttatgtc tgacatgatt tgaaatcgag
     1681 tgccttggac ggataaaata actttgagcg ttccaatggc ttcgacagtt tttacaggta
     1741 tagcgctgct tttttaggcg tataaccatt ggcatatgat tatattattc aaagtggaca
     1801 atggtttcct tcttcttgtt tttcaccacc attaatttcc tatttccatc taccacagca
     1861 gaaccacaat ttctacagac acatggagca gggaagagaa ctgcagcaac gatcaatgtt
     1921 tttttcttct gtaaggtttc gtaagagacc tctgtaatca tcaaattttt gtctattgat
     1981 ctcagaattt ttttgataga accattcata aagcatatcg ttctctcagt tgtttatttt
     2041 gtggtgattt aatcatacaa gaaaacgata tgttttttta taaaaacatg aataggaaaa
     2101 atagttgaca agaaaatgac aacgccatat gatgttccat agtatttaca acctgtcata
     2161 gatgactgta aaaaataaaa gtaaaaagaa aggacgacaa caggtggatt tttatcagtc
     2221 tctacaacta gatccgttta ttttaaaaca aaaaatacga gaagcagctt ctaaaaaaga
     2281 aaagtgcatg tatatttgtt cattgttttt acgatcatta ttcatcgtat tgtttgccat
     2341 ttgttttatc attataatta caacattatt tgaatcgaag cataaaccat acgctgtggt
     2401 tttattctgt atgttgatga gtattcgttt tgttgacttt ggttataaga tttcccattc
     2461 gatcataggt ttagcaatcg tcatgttctc actattagta gcaccgtatg tccagctgat
     2521 caaatggtca gttatgggca tgttgattca ttttatttta ctaagcagca tattaatggc
     2581 aaccgctagt gatcccaaaa tggggaatgc ttctttgtac ggcttttcat atctctttat
     2641 tgtttattcg ttacctaaag attcgttgaa caagaatttc tttacacaaa caagtagctt
     2701 attatttttg tttttttgtt ggttttcagt tctcctttac agaaaacatc gagaaaagaa
     2761 caaagacaaa agcttgttta aagagatttt tttgaaaggc atgtattcgc aggaaaaaat
     2821 ttggatgctc atctatgcat ttggcattag tcttttgatc gttgcaggag agtatgtccc
     2881 ttttcagcga ttgatgtggg cagggtttgc attttcttct attgtatcta gctatggatt
     2941 gatgtcgatt ggtttcaaag aacgagcagt agaccgaatc attggctcat tgattggatg
     3001 tgttttattt attggtatca gccaatttat tccttttaac tgggtcggta tattaggtgg
     3061 tctagcttta ggtgtttgtt ctacctatag atataaaaca gtttttaatt cttttggtgc
     3121 tttggcaatc actgccagtt tattcggggt tccaggagca gtaacgatcc gcatttttga
     3181 gaatatcctt ggggtatgtt taggaatcat gtatattggg gtgactgaaa tacttatccg
     3241 aaaaataaga gaaaaacacg gtttgaatca ttagatgaga tcgaataaaa aataaggaaa
     3301 aagtgaagat acacatggat gataaattgc tatcattcca tgtgtatctt tttacggtaa
     3361 atcagtgaaa cgttcgactt tcatttttaa tttatacttt ttacggagtt cgtttatttg
     3421 agccatcatt tcggatttgt gatgcttttc gattgcttct tcatctttcc aacggtcgat
     3481 cagtaaaaga gattctggat cttctagtgg aaagtaatag tcatatttct cgtttccttc
     3541 ttctgcacga atcgctttga caatgtttct ttcgaccatt tcttctgcaa attttctggc
     3601 ttgtccattt gtacttgtat acaaaatatt cactgtgata ctcactaaat cccctcctga
     3661 aaaaattcta tcactagtat atcacggtgc cagaaattat tattcaagat atgatacaca
     3721 ttttttccgc aatgctacgg aaatatatat tttgaataga aaacgcttac aagatatgct
     3781 tggtttataa aaataaaagg agtgattgat ttatgaaaaa agcattgatt atttgtgcgg
     3841 caggaatgtc atcctcgatg atggcctcaa agacaacgga tttctttaag caaaaaagag
     3901 aagaggtact cgtagatgca gtttcagcta cagaaggcga taatatgatt aagaatagtg
     3961 attttgattt atttctgatc agcccgcaaa cgacgatgtt tttggataaa ttcaaaaaat
     4021 taggagaatc tgttggaaag cctgttgtta gtatcccttt ccaagcgtat gtcccaatcc
     4081 ctacaggcat ccagaagtta gcagaggtga tcgaagagaa catatgatgg aataggagtg
     4141 gatgataatg aaacagaagg aaaaattgct gttgagatat ttgattgatc acaagaagga
     4201 gtatgtcacc agtcaacgtt tagcttctga attgttatta tctgatcgga caatccgtaa
     4261 ttacttgcag cggatcaaag agttagtaga aaaaaacgga ggtaagatca ttgctaaacc
     4321 aggttatggc taccaactgc atattttaca aagactgaca tttgacttgt ttttgagtcg
     4381 gcaagaaata gtacctggat atgctagaga accgcaagga ttttatgagt ccgaagatcg
     4441 acaaaagtat atattgaacc aattgctttt ggaagatgcc attcttttta tggatgattt
     4501 ggcagaagag ctttatatca gtcgttccag tttgacaaag gacatgcaag aaatcaagga
     4561 gcgattgatt ccatattcac taaaaatcgt ttctaagcat ggtcaaggga catggatcga
     4621 aggggaagaa agaaatcgac ggcattttat catggatact ttttttggaa accattatgg
     4681 aaattcattg aaagaatatt tagggcaaag ccgttttttc ccagacatca gttttgaaga
     4741 gctagtcatt atcattctcg atgaaacaag agaagctaag ttaaaagttt cggattttat
     4801 catacagaat ctgactttac acttggcttt ggggatcaaa cggctccgag aagggtttga
     4861 aatcaaggaa ttaggcatcg aacaagaagt ttctaagcga gtagagtatc aagtggcgca
     4921 gcggatcgtt caacgtattg aggtaatcgc aggtgtatcg tttcccgaag aagaaattgc
     4981 ttatttgaca ttacatctca tggctaagtc gaatcacaaa gaaaatcaaa atgatcagga
     5041 actatcaaag gaattagcga aagttctgaa aagattgtct caggaatttc atttttcatt
     5101 agtagaggat ctccagcttt tcaatggact actcgatcat ttgtcaccga tgatgattcg
     5161 attgagccga ggtattcgca ttgagaaccc attgactgag gagataaaga aagaaaatcc
     5221 caaagtcttt gacgcagtaa aaaggcattt cagcaacatg ccggctttga aaaactatac
     5281 catcaatgaa gatgaatggg cctatttggc tttgcatctc atggcggcat tggaaaaaga
     5341 aagagctgcg cataaactac atgcattgat tatctgtgca acgggttacg gcagtgccca
     5401 actattaaag aatcgcgtag tcagtgaatt cggtaaaaat attacagtgg taagtgtaaa
     5461 aggctattat gagatcaatg aaacaacttt aaaaggaatc gacctgatta tttcttctat
     5521 tgatctttcg acaatgtttt tcaaaattcc agttttacat gtcagtattt ttttgaatga
     5581 agatgatgtt cgtaaaatac gaaaggtagt tggagaatct ataccctatc attcctcaga
     5641 tagaccgata ccagcatttt ctctacagca aaaaaagcag atttacaccg aacagttgtc
     5701 tgaaaaattt ttcaagactt atacgtacga accgaaaaag gaagaaattc ttcatgattt
     5761 gctgcaaaag ctgagcataa atgaagaaga aggatatata agagaaatgc gaaagcagat
     5821 ccagcaacgt gaaaatatgg gacaaatcat attcagtgat acagtggcag tcccacatcc
     5881 cgctgttcca gttggaatcg aaacaaaggt agccgttgca ttgattcctt ctgggatgca
     5941 gtgggatcaa tatcaagaaa ttcattttgt ttttttagtt tcgccttctt atgtcgaaaa
     6001 tgaaggaatt acggtcgtga ctaaagcaat cgttaggtta gttgaccagc taaaagtaca
     6061 gcaggaaatc ttagctgaac ctatttttga gaatttcagc agtaaattta tcaaactgat
     6121 cgaataagga ggaaaacaga tggctgaaaa aataaacagt gaaacactac aagtgacttc
     6181 ttttgatatc attttccata gcggaaatgc acggacactg atacatgaag catttcgctc
     6241 gatgcgtaaa gagatgtttg aagaagtaga agagaagttg cgacaagcaa atgaagagat
     6301 tcttcatgcg catcagtcac aaactcaact tctgaaagaa tatgccagcg ggacaaaaat
     6361 agaaatggaa attatcatgg tccatgcaca agatcatctg atgacgacga tgacattatt
     6421 ggaagttgca caggaaatga attatttgta tcaaaaaaat aaatagaaag gaaggatcat
     6481 tgtgcaggat acagtaaaaa ggaaaatcga attagaaaaa aagcaactta gtttgaaaaa
     6541 catgtatttc aatcgttatc taatcgtacg ttacctgact gcctttttct ttttcatgaa
     6601 catgcaatgg atgattctgc ttctatcagc taaaagttta ggaagtagtt taccgatgat
     6661 tctgatttta gctattttgc ctgcagtagg agaacaagta aagctttatc gaaaacacca
     6721 aacgaacgtt ccatggacaa agtggtattt tttgttccag agtgtcttta atttattagt
     6781 gattccagtg ttgtttacct caggatttac attcttgtat ccttttatgg caaataacaa
     6841 tggaggacag ttatttgttt tcattcttgt tgtaagcggt atttttgcca gtgcatttat
     6901 acagtatcgt ttaaagaaaa tttcactcaa ccaagaccaa cagtatatcc gtattaaaca
     6961 atatgaaaaa gcgttatatt taggaaagga gaataactaa tgtttgattt tttgcagaaa
     7021 tacctgatgg gacctatggg gaaaattgcg caacttaaaa tcgttcgggc tgtcatggca
     7081 gcggggatgg cttctattcc tttcacgatt gtaggctcga tgtttttggt tttaaatatt
     7141 ttgccattac cgttcccatt tttagaagga ttttttaatg caactttttt caaagttagt
     7201 gacttgtaca tgatcgtcaa tacaatgacg atggggattt tatctattta ctttgccatt
     7261 gtgtttgctt atgaattaac gtcaattgaa cgagatgaac aaaaattaaa tgttaatccg
     7321 ctcacggggg cattactatc tgtttttgca ttctttatgt gtatccctga attgatcatg
     7381 actgatggta aaatcagctt gattgcttct atcaatgaga cagaaactgt agtaaatggt
     7441 attaggatgg gctcttttgt cgaacgttta ggaacttcag gaatctttac agctattatt
     7501 atgtcgatta ttgcggtcga attgtattgt atgtgtgtca agagaaattg ggtcataaaa
     7561 atgccagatg ttgttccgcc aggagtttct cgttctttca ctgctctgat cccaacattt
     7621 gtcattgcgt ttgtggtgat gatcatcaat ggattattag ttgcactagg aacggatatc
     7681 ttcaaaatga ttgctatccc atttgggttt gttacgcagt tgacgaatac atggcttggt
     7741 gtcatggtga tttatttctt gatccatgca ttgtggatcg tagggatcca tggagcgaat
     7801 atcatcactt ctttcttgac cccgatcgta ttagctaata tggcagctaa cgcacaaggc
     7861 gcaaattatc cgttggcagg agaattcaac aattcttatg taaccgttgg tggatcaggt
     7921 gcgactttag gattgatcat ctttattgca ttcctcgcga aatctgatca gctgaaagtg
     7981 ttaggaaaag cctcacttgt accaggatta ttcaatatca atgaaccaat cattttcggg
     8041 atgccaatcg tctacaatcc ctatttagcg gttccgtttt tcttagctcc gatggcttct
     8101 gctacactcg cttattttgc cattcggctg gaaatcgtca aaccgatgct tgcacagatg
     8161 ccgtggcctt caccagtcgg gatcggagca tttgttggta gtggtggtga ttggaaagct
     8221 gctgtgttag cagtcatttg tgcaatcatc gcattcatta tctggttccc atttatcaaa
     8281 ttctatgata ataaattatt aaatgaagaa agagaaaagg cagcagaatt agctagtgaa
     8341 aagttaaaat gatttctaag aaaaaaggaa ctgtgacaaa aaatcacagt cccttttttt
     8401 cttagaaatg ggaaaccact agtatataaa taccattatt cttcaatcaa ccgcttcacg
     8461 attgcataat ccccttcata aggttcatct acaccattga ttttttgata gggatccacg
     8521 ccttttcccg caataacgac tgaatcttgc ggagcgcttt ctgctaaagc gcgtcgaatc
     8581 gcttcaggac gatccatttc ataatgaacg atcaaatctg gattagtaat tgcttcattg
     8641 atttcttccg cgattttttt cggatcttca aatgctgggt catctgccgt caaaaaggcg
     8701 atgtcagctg tttctgatag cacttttcca aaatcatgtc gacgggagat tgctttgttt
     8761 cctgggctgc ctaatacaac aattacacgg ccatctggat gttcattttt ggcaaatttc
     8821 agcaatgttt tcaagcttag ataattatgt gcatagtcca catagacatg cgctccattg
     8881 gattggatca attgatccat tcggcctggt acacgagctt cttttaatcc gtcttgtgca
     8941 tcttgactgg aggcacctgt tagtgctgcg gcaatgatcg cactggctgc attttcttgg
     9001 ttgaatcctc cagccagcaa aatatcataa gcagtatcgc agatagctaa gcgatcttca
     9061 tgagaagata aagtaaaacc gtgagtacct ttatctgaac ggatcacttg ataattgctt
     9121 tcttccgaac gaccataagt gatcgttgga atctggaata gatcggctgt ttccctaagt
     9181 aaatcaaaat agtcactttc atgatttaaa acaactgttt ttgaattcaa gatcaattgt
     9241 cgcttgcaat agaaatagtc atcaaatgtc ggatgttcga tcggactgat atggtcaggc
     9301 gagatattca agaagattcc gacatctaaa gtcaagccgt atacgcgttg tgttttgtaa
     9361 gcttgtgaag aaacttccat cactagatga gtcataccat tttcaactgc ttctgacatc
     9421 atacgatata aatctaatga ctcaggcgtt gtcaaatggg atttgaaata tgttttgcca
     9481 tctaacgttg tattcatagt agaaagcaat gctgtttttt tatttgttgt gtgatccaag
     9541 attgcttttg taaagtacgc agcagttgtt ttaccttttg ttccagtgaa tccgatcact
     9601 ttcaatttat tttgcggata gtcgtaaaaa gccatagcaa gaagcgccat tgctttacgg
     9661 atatccgtta cgatgattcc tactgctgaa ttttcgtatg gttgttctga tacataatat
     9721 tgaataccct gttcgattgc tgaatccaaa tattcttctt tgaaattcat tcctttacag
     9781 aaaaacaaag tagaagcatc agcttttctt gaatcataac ttaactgaag aaattcagct
     9841 ttttctggta catcaagatg ccagcctctt gttgaaacaa attcttttaa tagattttct
     9901 tttaatagta aatgacggat gtcttctaaa gagaagctca ttgattgatc cctcgcttta
     9961 ttcaatttct tggtttatta tagcacactc tttttaatat atcgtttgtt tccgctatga
    10021 caaaatccag ctttattcaa attttcttga cacaggggac aagcggatga gtattttcat
    10081 aaacaatgaa ctgactgtaa tagataggag aacgaatagt gtctccaaca atccaaaaac
    10141 ataataattc aaaaagacga taagactatt ggtaagtaaa agtccttgcg gcattggaag
    10201 ccgaaaaaat ttgtggaaaa taatcggcgg tatcgttata ccgccatttg aggccccgac
    10261 tgtgtacaat gtgtaaaccc caagactgaa caaaagactt cctgaaatca gtgaaaagaa
    10321 atgtgaggag atcatttcca cttttggaac aatctctaaa acaacaggaa aaagcagact
    10381 tcccgctaca gtcttaaaaa atactgattt tcctaatagg acagcggcta gaagcagcat
    10441 cataagattg atgctccaaa cagtaactga gcgttggata gaaaaggccg tttcaactaa
    10501 atgtccgatg gcgcccactc cggcggaagc tatatcgtga gggagcaaga accaattcaa
    10561 tccaactgtg ataaagaaaa gacctaaaaa tataacgggt agttttttta tttcttgtgt
    10621 cattgatatc tcctataaat gttagccata aaaggctgta tatttcttta ctttaccaaa
    10681 aaaacgaaac cgaattcaaa aaaacaattg ttcttataaa agttatataa aatcgattgc
    10741 cagtttctgt tttaccaatt aaaatgatag taatgttttg tagaaagttg gaatctgacc
    10801 gatggataat caaagaaaac cagcattaga tcaattaaca ccgcaagaaa aaatggcacg
    10861 aggctctgct tggatgaccg ccagtaatat catttcaaga ttgctaggcg ctgtctatat
    10921 cattccctgg tatgcttgga tgggcgaaaa tgctaaggct gccaatggat tattcaatat
    10981 gggatacaat atatatgcat tgtttctact gatctctaca gcaggaatac ctgctgcgat
    11041 tgcaaaacaa actgcacgct ataattcatt gaatgaatat ggcacttcac gacgattatt
    11101 tatccgtgca ttacagatga tgggcgggtt aggcctgttg tttgctttgt tcatgtacat
    11161 cgcctctcct tggctagctc atgcttctgg tggcggagaa gaactgattc caacgatgcg
    11221 ttctttgagt atcgctgtat tggtttttcc ttgtatgagt gtgatacgag ggtatttgca
    11281 aggcaatcaa gaaatgatgc cttatgcgct gtcgcagatt gtagaacagg tggcacgtat
    11341 tttttatatg ctattggcta cattcatcat catgaaagtc atggatggtg actatgtgac
    11401 ggcggtcacg caatcaactt tcgcggcatt tatcggtatg ctagcaagta ttcttgtcct
    11461 tttgtatttt ttgaagaaac atcaagcgta tacatcggcg tttattcact acagcgaaaa
    11521 caaaataaat attgcaacga aggaattgtt gttagatacc gttaaagaag cgattccgtt
    11581 tattattgtg ggttcagggg taacgatctt caaattagtc gatcagttca cttttatgaa
    11641 gatcatgtct gcatccaccg agtattccaa tgcacagtta ctggatcttt tttcgatttt
    11701 tagtgccaat ccagataagt tgacgatggt agttattgca ttggcaacat cgatcgcgtc
    11761 tactgggtta ccgttgatta cagaagctgt tacgttgaaa gatcgagtag gtctggcaaa
    11821 attgacaagc ggaaatttac agttgttttc attttttatg tttccggcga catttggtgt
    11881 tatgttactt gcctatccgc taaatacatt attttataca ccggattctc taggaagtaa
    11941 tgtactgatc caagcaagtt ttgtaggact cttcctagga ctatatatgc tagtttccaa
    12001 catgctgcaa ggaatgtttg aaaacaaggc ggcaattaat tatttggtta ttgggtttct
    12061 agtgaaactc cttcttcaat acccagccat tcgtttattt gaagtatacg gccctttatt
    12121 ggcgacaatg atcggatttg ctgtgtcttg taccttgatc ttaaagagaa tccatgaagt
    12181 agcccgcttt aaaccaagtt ttgtctggcg caggacattg ctgatcttta ttcttacctt
    12241 gattatgctt ttggcttcgt ggatcacaaa gatgattttt ggtgcttttt taaacgaaga
    12301 tagcaaattc cagtctctat tgttgattct tgtagtagca ggtatagggg ctttagtgta
    12361 tggttattta gctttgaaaa tccgcttggc agaaagacta ctaggaccag gaatagcgcg
    12421 tttacgacat aaattaaaaa taaaataagt gaatcagaag agctagattg atgctctttt
    12481 gaaatggggg aaacgcatgc gtttagataa gtttttagca gatatgggac ttggcagccg
    12541 caaagaagtc aaaggattaa tcaaaaaagg aacgatcgaa gtcaatggac aagtggtgaa
    12601 aagcgataaa gcgcaagtaa atgaattcga agatgcggtt acttatttag gagaaatcat
    12661 tacgtatcaa aaagattttt actacatttt gcataaacct gcaggagtca tttctgctac
    12721 tcaggataat catgatcaaa ccgtaatcga tttattggaa gaccaggatt atcgggaaga
    12781 tctttttcca gtcggccgat tagataaaga cacagagggc ctcttgattt taacgaatga
    12841 cggggtgttt gcccatcagt tactatcacc taaaaaacat gtggagaaag aatatctagc
    12901 tgaggttagc ggtataatga cagaagaaga tatccgttta tttgcagaag gactgattat
    12961 tgatggcgat gagcagacat tgccggcaaa actccaaatt gatcaagtag atcaagagac
    13021 agaaacttca attatccgtc tgattttgca tgaaggaaag tttcaccaag ttaagcgaat
    13081 ggtcaaagca gtaggaaaag aagtcttata tttaaaaaga atccgtatgg gaaaattttg
    13141 gctgcctaaa gatttgaata aagggcaata tcgacccatg accaaagaag agctagaaca
    13201 agtgagagaa aaataattga atggatagct aaaagaataa gcagagtagt tgtagcgcca
    13261 tctgaaaagc agacttgtcc gtctgacttt cggatggctt ttttgtgaaa tttcggctta
    13321 tttccgtaga agctacttct ggaacaccgt ttgttcggaa taagggactg tgacaagact
    13381 tttgttacag tccccattgt tccttgtgac tcagagttag atagtaagga cacgatctcc
    13441 ctaatactca ggccaaaacg ctgaattcac aacctctgat aaacggtgtt caatcagctg
    13501 accctcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttccc gtttttttct
    13561 ctaatactca ggccaaaacg ctgatttcac aacctctcct atactttgtt tcattttccc
    13621 tatactttgt ttatttattc tcattattga aagcgctata attacgttgc gaatgaatcg
    13681 aaaggggttt ttagatgaaa aaacgaaagg ggttcaatca tttttttatg aatctatggc
    13741 gttataaagc acttgtcctg atggctgtac cgggtatgct ttggatgatt tttttctttt
    13801 acatacctgt aatggcgaat gtcgtagcat tcaaaaattt tcatatttca gcagatgggt
    13861 tcttggctag cttgagggaa agtccttggg tgggttggga aaatttcaaa tttttatttt
    13921 cttcggatca agcatttctc atcactaaaa atacaatttt atataatgta gcatttatcc
    13981 ttttgaatct gctgatctca gtcgtatttg caatcattat gagcgagttg agaaataaac
    14041 gactcgttaa agtttatcaa acgatgtcct tactacctta ttttctatct tgggtcatta
    14101 tcagttactt tgtttacgct tttttaagtc ctgacaaagg aatattcaat cagtggatca
    14161 ctggacatgg aggagaagct gtcaattggt ataatgaacc gaaatattgg ccgtttatct
    14221 tggtgttcat tggtacatgg aaagggattg gttataacag cattatttac tttgcatctg
    14281 ttatgggaat cgatccgact tattatgaag ctgctatggt tgatggagct agcaaatggc
    14341 agcagatcaa acatgtgacg ataccacaac ttattccact aatgacgatt ttaacgattt
    14401 tagccgtagg aaacattttc cgagctgatt ttggcctgtt ttataacatt cctaggaatt
    14461 ccggtgcatt atatgatgtg actcaagttt tggatacgta tatctacaat ggcctgacat
    14521 ccacaggaga ttttggtatg acggctgctg caggacttta ccaatcagtt gtcggctttg
    14581 tcttgttgat gatcacaaat acgatcgccc gacgttttga tagcgattct gcattattct
    14641 aaggaggaaa aaaatgaaaa aaaagaaagt ggagagagtc caagtccgct ctttcaataa
    14701 gacggctaat tttttctcta atataatgat tgcactcttt gctatttcct gtattttgcc
    14761 atttatattt gttatcgcca tctcttttac cgatgagtcc atattgtcga ctcacgggta
    14821 cagtttttgg ccagaaaagt tcagtatatt tggttatacg tacttgttcg accagatgca
    14881 ggataaaatt ttccaagcgc ttttcgtcac tgtacttgtt actgttttag gtacactgat
    14941 caatagcacg gctacttctt tatatgctta tgcgatttca cggtcaaact ttccattccg
    15001 tcgttttttt accgtttttt gtttgattac gatgttgttc tcaccaggga tggtggccaa
    15061 ttatcttgtt atgacaaatc ttcttcagtt aaaagatacg atttgggcat tgatcttgcc
    15121 aatggctgtc agtcccttca atattattgt gatgcgcaca ttctttaaac gttcggtctc
    15181 tgattcgatt attgaatcgg cacggatcga tggagctagc gaactgcgaa tatttgttca
    15241 gatcgtttta ccgttagctg ttccaggtat tgcgacaatc agtttatttg ccgcattggg
    15301 ttactggaat gactggttca atgctttact atacatccaa gatgataagc tagttccact
    15361 acagtatctt ttgatgaaaa tccaaagtaa tattcaatat ctgacacaaa attcaggagc
    15421 aggaagccaa ttgacaggcg gattagcctc agttccagga gaatctgcca gaatggcgat
    15481 cgtagtcatc tcgacgttgc ctattgcgat cagctatcca tttttccaga agcattttgt
    15541 caaaggtcta acaatcggcg gagtaaaaga ataaagaaac aaaaatataa atcataaaat
    15601 taggaggaag aaaaatgaag ttatggaaga aactagcctt tacaggtgtt tcagcgttgt
    15661 tgttgggaac attagcagca tgcggaggtt ctggttctaa agaccaggca gaagctagca
    15721 attcggacac tttgcagatg tatcaaatcg gagataaacc agataatttc gatcaattga
    15781 tggaagtagc aaacaaacga atcgaaaaag agatcggtgt aaaagtcaat atcaattaca
    15841 ttggctgggg cgattacgaa aagaaaatga acgtcatcat ttcttccggg gaaaattatg
    15901 atatcgcctt tgcgaacaac tatgtttcca atgcccaaaa aggagccttt gctgatttga
    15961 ctgaattagc gcctaagtac gctgaaaaag cttataatga tttagatgaa gcatatatta
    16021 aaggaaatct ggtcaatgga aaattatatg ctttcccagt caatggaaat gtctttgctc
    16081 aacaagtact tacttttaac aaagctttac tagataaata cgatctttca attgatggaa
    16141 tccaatctta cgctgatgca gaaaaagtct tgaaggaatt ccatgaaaaa gaaccaaaca
    16201 cggcagcttt tgccattgga caaggcttca aagtccaagg gaactttgat tatcctttag
    16261 ggaatacgtt accatttgct attgatctgg atggagatga ttcgaaaatc atcaaccaat
    16321 acgataatga aacgtatatc ggactgttac gtacaatgca tagctggtac aaacaaggac
    16381 tcattccaag tgacgctgca acgagcaata aggattatcc actagaagga aatacttggc
    16441 taatgcgtgg agaaacacaa ggaccgtatg attatggcga tacaattttg acaaatgcag
    16501 caaaacaaga acttgtctca aaagcaatta ctgttccact aaaatctaca gctcaagcac
    16561 aaatggcaaa ttttgtcgta tcaaatactt caaaaaataa agaaaaatca gtagaacttc
    16621 tagggctgct taacagtgat ccagaattat tgaatgggct tgtttggggg atcgagggag
    16681 aagcatggga aaaagtcgat ggttcagatg ataaaatcaa attgctagat ggttatcagc
    16741 caaatacaca tatgtctgct tggaatacag gaaacaacaa gattctatat acacaagagt
    16801 ctattacgga tgacatgatt gccaaacgtg atcaatcgat tgctgatgca gaaacttcac
    16861 cgattttagg attcagcttc aacactgaca gtgtcaaaac agaattaagt aatatttcta
    16921 atgtcatgaa tcaatattta gatggattga atacagggac tgttgatcca gatgaaacat
    16981 taccgaaatt gaaagacgct ttggacaagg ctggctatga taaggtattg aaagaaatgc
    17041 aaaaacaata tgatgagttc cgacaagaat aataatgaat aaagacaaag gggttgtgac
    17101 aaaagacgtg tcacaacctc ttgttccgaa taaacggtgt tcaaaagcca gtttctcggt
    17161 attaagctaa atatatgtaa aaatgtggaa agccatattc acaaaatttt tcttactact
    17221 cgaaactaag cggctatttc acaaactctt ggtaaacggt gttcaatcag ctaaccctcg
    17281 gtattcgctc acaaaacgac aaaatatgag gaactatttt tccgtttgtt tctctaataa
    17341 tcaggtcaag gtgctgattg cccaaccttt ttttgtataa tgagaaagta taaacttaat
    17401 gtttggagga gaagatatgt tagggaaggt tttggaagag ttatttatcc ggatctgggt
    17461 cattataaaa ctaaccttgt atttctggat atatacattt gccggcggga tcatctttgg
    17521 attaggtgcg gcatggaaaa cagtcaatga actattttat ttgtacggat tcgagtataa
    17581 agaaatcaca ataaaaagag gctggaatat atataaaaga aattttttaa gaggcaatct
    17641 gctatttagt ttatttttat ctggtactgc tttattgagt tacaatttat atttatctgt
    17701 tcaaatcaaa gggctcattt ttttagctat tgattttatt ttactttttg ccttgctctg
    17761 cctatttgct acttatcaat acagtatgat tttagatagt gaatatacga tctctgttcc
    17821 taatctgcta aagctaagtt ttatttcggt tttttccagc ttttcgtctt ttctaaaaat
    17881 aattattggt agcggtataa ttttaggcgt gacttggcaa ttcaaaggat tgatcctgtt
    17941 tggtgtcatt ggtcttttga cggtttggaa tggtacgatg acaacacatt ggcgtgaaga
    18001 attagataaa cagttggaaa gttatgaata agtttcggat tctattttca aaaggaacct
    18061 tactaaatcg tctgttgcgg aaatacgcgg ttatcatgat cggtgtaacg atgactgcta
    18121 ccgttatttt tagtatccat acttgggaac aaaatcaaaa acaggcagaa aacatgacaa
    18181 gtgatgccgt tcaaagcaca agcagaatgc tgaatgataa aacaaccttg agtaggatca
    18241 tcaaaaacca gcttgtaggg aattccgaaa agatcgaaaa tgtgacgacc tacttaacaa
    18301 aacccataga tcagtatctg atgtatgtat acgaacagca aaacagtacc gatgaattag
    18361 tttctttccc aaatcaaatc aaagatctct acgcaaatta tgaagaacta agtgcgatat
    18421 atatcgtgtt gaatcaacta ccggagtatt atgaatcttc tagagaaaac aaaggtgggg
    18481 aaataaaaaa ggggacacca aaattactag acgcctttta tatcaagttg cctatcacac
    18541 aaggaggagc tgagtcagga agtattttta ttggttttca aaagaaagaa ctagatatga
    18601 ttttagaaaa tctaacgtca ttcaatggac tctctttata catgatttct ggaacgacaa
    18661 atcgactata cacattccat gataataaaa tagctaaaga aacgtttgaa agacaagaaa
    18721 tgatcatcac agagagtctg aagaaaaatt cacaattgcc gattgacgat ctggaaaaaa
    18781 acaattttgt tcaacaccaa gaactgtctg atgattatcg tatattagct gtactagata
    18841 aaaaaagtgt aaaaatcgaa acgggaaaaa atcttgcccc gctgatcatt ggtatcatta
    18901 ttttagacaa tatactgctt atctttcttt ataaaacatt caaacgatat tcacagcaag
    18961 tatctatcgt catgcaggcc atggatcaaa cagcagcagg gaatttagag acgcggatcg
    19021 acataacaaa cacggaatat gaactgaagg aactttcaat cggtatcaac gaaatgttgg
    19081 atagcatcaa tcagtttgta gaagacatct acaaattaga aatcaaacag caagacgcac
    19141 atatgcgggc gcttcaagca cagatcaatc cacacttttt atataataca ttagaatata
    19201 tccgaatgta tgcaatcagc gaaggaagtg aagaattagc agatgttgtg tatgcgtttt
    19261 ccgctttgct tcgaaacaat acgaatcaag agaaaacgat cactttaaaa gaagaactgg
    19321 acttttgcga aaaatatgtc tatttgtatc aaatgcgtta tcctaatcga gtagcctatc
    19381 attttatgat cgatcctgat ttggaaaaga tcgaagtacc taaatttgtg atccagccat
    19441 tagttgaaaa ttattttaaa cacggtattg attttactcg attcgataat gcgctaagtg
    19501 tcaaagtctt gcaggaaggc aaacgggtaa ggatcatcat caaagataat ggaaaaggga
    19561 tgactgaaaa acggctaaaa cagattgaag aaaaactgtc tcatcctaaa gtggaacttc
    19621 acggttctat cggtctgcaa aacgtgaatg aacgtttacg tgccagcttc ggcagcagtt
    19681 attatatgtc gcttgagaat aatgagacag gtggactgac cgtttctatt acattcaagg
    19741 agggatgagc gtgtatcaag tgttattggt agatgatgaa tacatgattt tgaatgggtt
    19801 aaaaaagata attgattggc aaagtttagg ctttcaaata gtagcaacag cagagaatgc
    19861 caaagaagga ctagctgtac ttgaacagcg acagattgat ttagtagtaa cggatgtgac
    19921 aatgccagaa ataaatggac tggaatttat tgaagcggct caaaaagaac gtcataattt
    19981 tgaatttatg attttatcag gataccaaga attcgattat ttgaaaggag gtatgcaatt
    20041 aggcgccgtg aattatttga tgaaacccgt gaataagttc gaattggttg aaagcctcaa
    20101 gaaaatcaaa acacggttag atcagcaaaa tgaacaaaaa aatcaacaag aaatctatca
    20161 agaactgtta ttcagtcaat ggttgaatga agaattggat gaaataagtg aagaagaaat
    20221 aataggacaa ataagtgaga agcagcatag gatagtattg attcaactgg caagaactca
    20281 tgatactctt atcaatagat ggttgcaaga acggcaacaa atcttttact atcaacgaaa
    20341 ttacggagac cgtgtattga tcacgttgtt gttggaggca gatgaagttg atggcttctg
    20401 ttgttttgtt caagaaaact ttcctgatca ggaatggctg atcagtatcg gggaagagac
    20461 agattctttg gacaaaatcc ctgaaacatt ccaacaagcg aaagacaatc tacagttgca
    20521 tcaattttat ggagataaag acgagcatgt tttttacgca gtacaagcag aaacaaaaga
    20581 tcaaaccatc gatttttcaa gtttcagacg cgtgctgcaa aataaacaat tggaagtcgc
    20641 tcaaaaaatg atcactgatt tttttgaaca gtttcagtta gcagccatga tgccggaaga
    20701 tatacgatat tccagttttt tactgtttat ggagattcaa cgggaattga ttgatctgga
    20761 agatgaggaa tatttacaag gaatcgaaaa aatccatcag gcaaaaacgg tgcaagaact
    20821 tcagcagcta cttctgtcat tcatcaaaaa gcatcagaga cagaaaaagt acagtgacaa
    20881 tgtggaaaaa gtaatcgtaa tcctgcacca gcattatcaa gaaccactta cactcaaaga
    20941 agtgtcagaa aacctgcatt taaatgtcat gtatctagga cagctgttca aaaaagaaac
    21001 gaaaaaaagt ttttcagctt atttgaacca tttacgtatg gaaaaagcga aacaactgct
    21061 tttgcacagt aatcaaaaca tcaatgagat agcaagtgag attggctaca acaacaccac
    21121 gtatttctct aaattattca agaaaatcgt cggcagatcc cctaaagagt accgagaaaa
    21181 cagtggagaa tcataaaaga aaaagccaat gtaatgaaat aacttataaa aaattgtcta
    21241 gaaatctaat tttgggctgt tcttattact tgaggcaagg cagctttttc atgacctctc
    21301 gataaacgga gttcaaaagc cagtttctcg gtattaagcc aaatttatgc aaaaatgtgg
    21361 aaagccattt tcacaaaatt tttcttaata ctcgaaacta aacagctttt tcacgacctc
    21421 tccactaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaat ggcaaaatat
    21481 gaggaactat tttgccattt gtctctctaa tactcaggtc agaacgctga tttcacaacc
    21541 tctcaataaa cggtgttcaa aagcttgcat ctgcggtaat aagaccaacc aaacgaaaaa
    21601 tatgaggatc tatttttgct tggctgttct tattacttga tgcaggacag ctttttcaca
    21661 acctcttgtt aattatagtt tgataaggaa aaaggcaaat cttttgcttg atatttctta
    21721 gggtgaggga tgatccctaa ttggtaagag atcgtgccgc ctttcagcaa atcttgatgg
    21781 gtaaaatata atttcgtata ttctttgtcc atccgtttga ttttatggat aaattgttgc
    21841 tgcggccgat taggcgttgc ttcaatcgtc aattcctttc catttgacaa aagcaaaaca
    21901 gccttgtcaa ttaatggcat accgataaca tattcaccgg ttccaggcgt gacaggataa
    21961 aatcccagac tattgaagat ataccaagcg gccatacttc cattgtcctc atctccaggg
    22021 taacccattg gagaatcgtc gaaggtctga gtcatcaact gtttaagcag tggctgtgcc
    22081 atttcaggtt gtcctatata actgaacaag taaggatagt gaaaacttgg ctggtttgaa
    22141 atagctaatt gtccaaattc tatcgcggcc atctcactca tttcgtggat ctcaaaacca
    22201 tatcctcctg ggtcaaacgt tgggggctga ttgcacagct caatgagttt ttctttatat
    22261 ctctcactgc caccatattt tccgatcagt cctgaaaaat cgtgataaac agcaaagctg
    22321 ctttgccaag cacttccttc tgcataatct tgtccccaac gattagctga aaatggttct
    22381 ctgaacttgc catctttatc ttttgaacgc ataaatcctg actcatagtc aaagatattt
    22441 tgatagttca atgattgctg ctgatatttc ttcgtcattt cctcttcttc tagtaccttg
    22501 gcaacttggc taatacaaaa atcgctataa gcatagtcta atgtgtgatt gactgattcg
    22561 tggtagtgat taggaacata gccatatgtc aagtaatctt ctgttccttg gcgtccataa
    22621 tttggatgtt tgctttgaac cgtagcacct ttttccattg ccgttagaaa ttcaggcatc
    22681 aagtctcgtc ggatatcttt tacagcagca tctgcaatga ccgcatcgat caatgtccca
    22741 ggcataagtc cacgttcatc aggagacagc cattttggca aatagccact ttctctatag
    22801 ctgttcaaaa aaccttccag catttcttcg tatttttcta cagcaatcaa agaataaaga
    22861 ggataaaccg ttttatacgt atcccaaaac ccattatttg tatagagaac accaggtttt
    22921 atagatcgac tagtcgtatc atagtggatt ttttgcccac taggatcaat ttcataaaat
    22981 gtttgtggaa ataaaaacac ccgatataaa ttatgataaa acgtccgcaa ttgttgttga
    23041 tcatggtgtg tgagctgtat acgatcaaaa taggactgcc attgttcttg actgtgagca
    23101 aggtaagtct ctttgctttg gttttgttct agttccaggt tataagctgc ttgttccgag
    23161 ctgataaaag atgtcccaaa tcggatagtt tgtttttttg tctgttcaaa atacaacggg
    23221 atcgagtcgc tatttttgtt ggaaacagct aactcatcaa ttgttaaagg atattcaaat
    23281 ctcaatataa aataaaaaga aaaatcagga tcttctgaac cagcaaaatg tgtgattttt
    23341 ccttccactg tgtaaggatc tataacaaag agctgatggc gtcccggaaa ggataaaagt
    23401 aaaccgctgt catttttgct gtaatcaata gataagattc cgccatacat gctaggtatc
    23461 aatgtagaac agatgccata acgtaattga cagatcgaca gatgagtcgg gcaaaatata
    23521 ctttcttctg ggcggtaaga actttgagca tggaaaaggg tgttctcctg tagttttcca
    23581 ttgatcggcg taaacagcat atgactgaaa tcacccatcc aaggacttgg ttgatgggta
    23641 agacggtagc cttgaaaaac gcggtcatca ggatgaaacc accagctgcc gttttgatcc
    23701 gtagtttgcg gtgcaaaata attcatccca aaaggaacgc cagtataagg ctggcagttc
    23761 ccattagaga aatttggctg attcgctgtt gcatgtctag tatctatttg accgatattc
    23821 attttatttc tcctttgttg attgtctttt gatgaatgaa actggaaatt tactatcgga
    23881 tggtcgatct tttgtctcta accaagtgac caaagcatct cccgcaagct tacctaactg
    23941 ttcaaaatct tgtgcgatgg ttgtcagtgg cgggtcaaca agagctgctg cttggatatc
    24001 atcaaatccg ataattgaaa aatcttcagg gatatgataa ccatgctgtc tcaagagatt
    24061 catggtctgg atagcgacaa catcgttttc acaaacaaaa gcagttactt catacttagt
    24121 gatataagaa agcaattcat ctaatgtcgc gcttttgtca tccagtgaag tgtggaaagt
    24181 caaaccagct ttgtccaatg cttcaaggta accaaggtaa cgctgtcgaa cggattgtgg
    24241 atgagtctgc gtaccaaaca aataagcgat ttttgaatgt ccctgttcga tcaaataaga
    24301 ggcagcaagc gcaccgcctt ggaaattatc ggaaagaacg gtaggaaaag gtaactcata
    24361 gattttttta tctaatatga cgacagggaa ttctttcaat gaaagctcaa aaagtaagtc
    24421 aagatgttgt tctgtatcaa gagcataata aatcaatccg tcaaattcat tgattagctc
    24481 ttttgctgtt ttattttgta gaaagtcaag cgtcgtcatc atgacatcaa tctgtttatc
    24541 ttgcatcaca gggttcaatc ccttgctaaa atcaccaaca gacaaatcag cgacatatgg
    24601 aagaagaaac agaatccgtc gtgtttttgt aggagaagca agaatctgtt ccggagaagc
    24661 ggatttaacg aaactgcctt tcccgcgaac gcgataaata agtcctaatt gctctaattc
    24721 agtcaatgca cgtttggaag tgattctgct tactttatag gtacgtgaaa gttctttttc
    24781 agttggtagt tggctgtcta caggtaattc accagttaaa atagccgttt gcaaatcatt
    24841 aaatattgtc tggtacaatg gttgattcat ataaacacct cttaatgata tatcatattc
    24901 aaataatacc ataatggatg aaaaagtaaa taaaaagata ttttttgaaa gcgtagacat
    24961 aattggctgt atgaagtata atctttaaag atatatcaaa tagaaagaag gttttattag
    25021 tggcttataa agatatacca aaatcggtgc agaaatttat ggaagatatc acacaaaaat
    25081 gtggggatat ccatgcggac tgggcaaaga attttacagc agcatttgcc aatactctgt
    25141 tgacaacagt caaaaagcaa aatgacggaa ccaccttttt attgacggga gacattccag
    25201 cgatgtggtt aagagactct actgcacaag ttcgtcctta tttagtgatt gcaaaagaag
    25261 atgaggaatt agctgacatg atcagcgggt tagtcaaaaa gcaatttttt tatatcaata
    25321 tcgatccata tgcgaatgcc ttcaacgaag aagctaacgg tgctggccac caaacagatc
    25381 atacaaaaat gaacgattgg atctgggaaa gaaaatatga aattgattct ttatgctacc
    25441 caatacagtt ggcctatctt ctttacaaaa atacaggaaa aactgatcaa ttcaatcaat
    25501 cttttattga aggtatcaaa aaaatcttgg acgtgttcaa aacagagcaa gatcatgaac
    25561 actctcctta tacatttgta cgagacacga caagaaaaga agatacgctg atcaatgacg
    25621 ggcgaggtgc aaaaacagct tttacaggaa tgacatggtc tggtttccgt cctagcgatg
    25681 atacttgccg ttatggatat ctggtaccat ccaatatgtt tgcggtggtc gtgttaggtt
    25741 atgtggaaga aatttttcaa acgatactcg atgataaaga aattgtacag caaacacaga
    25801 aattgaagaa agagatccaa gaggggattc agaatcacgg acgaacggtt aatcaaaaag
    25861 ggcaaacgat ttatgcatat gaagtagatg gaatgggaaa cgccacagtc atggatgaca
    25921 gtaatgtgcc caatctgatc gccgcacctt acttgggata ttgttctgaa caagaggaag
    25981 attatctgca aacaagaaga acattgttga gtaaagaaaa tccatatttc tatgaaggaa
    26041 agtacgcaaa aggaattgga tcctcccata cgccagaaaa atacgtttgg ccgattgcat
    26101 tagctatgga aggaatgaca acgtcagaca aatctgaaaa agagcggata ttgaatttac
    26161 ttgtagcaac tgacgcagga acacacctta tgcacgaagg attcgatgtg aacaatcctg
    26221 aaaattatac gagagaatgg ttttcttggg caaatatgat gttttgcgaa ttagtcatgg
    26281 attactttga tattagagta gaaaagtagg aggtatcgta aatgaaaaag aaagtatata
    26341 tcatttctca tagccactgg gatcgtgaat ggtacatggc ttacgaacag catcacatgc
    26401 gactgattga attgatagac gatctactag agctatttga agttgatccg tccttcaaca
    26461 gttttcattt ggatgggcaa acgattattt tagatgacta tcttcaagta aggccagaaa
    26521 aaagacaggc aatccaacaa gcaatcaatg aaggaaaatt gagaattgga ccattttata
    26581 tcttgcaaga tgattttctt atcagctcgg aatcgaacgt gagaaatatg ctgattggca
    26641 tggaagaaag ccgtaaatgg ggaacccctg tcatgttagg ctattttccc gatacatttg
    26701 gaaatatggg acagacgcct caattaatga aacaagctgg tatttcagca gcagcgtttg
    26761 gccgtggtgt aaaaccaatt ggctttgata atcaagtttt ggaagcagaa aactattctt
    26821 cccaatactc agagatgtgg tggaaaggac ctgatcaaac agcaatcttt ggtctgctat
    26881 ttgccaattg gtatagcaac gggaatgaga ttccagtaga aaaagaagca gctcttgcct
    26941 tttggaagca aaaattagcg gatgcagaac aatatgcctc tacgaaccac ttattgatga
    27001 tgaatggtgt tgatcatcaa ccggtacaaa aagatatatc aaaagcaatc catctcgcaa
    27061 atgaactgtt tccagattac gagtttattc attctaattt tactgactat ctggaagcag
    27121 ttcaaaaaga tgtgccagaa gacttaggct cagtagaagg agaattgaca agtcaagaaa
    27181 cggatggctg gtatacttta gccaatacag catctgctcg ggtttactta aaacaatgga
    27241 ataccaaggt ccagcgacag ctagaaaata ttacagaacc acttgcgacg atggcttatg
    27301 aagttagtgg aaactatccc catgatcaat tagattatgc ttggaagaca ttaatgcaaa
    27361 atcatcctca cgacagtatt tgcggttgtt cagtcgattc tgtccatcgg gaaatgatac
    27421 ctcgttttga aaaagcagat gaagttggaa agtatcttgc acaagattcc ttagaacagc
    27481 tgaccgcagc aatcgatacg accggattcc caaaagacag ctttccattt gtcattgtaa
    27541 atactgcagg aatggataaa actggtgaag cagaaataac catcgaatta gaaagaaaaa
    27601 gattcgctga aggaatacct gaacaactat atcaagagtt agaaaatttg cctaaacgta
    27661 agtatcatgt agaaacaaaa agtggggcca ctataccagc tattttatct gaagaaactg
    27721 tccaatttgg ttatgatttg ccgaaagacc gtttccgtgt gccatatatg gcaagaatga
    27781 tcaaagtgac tttaccatta gaaaacatgc cagcattttc ttgggaaaca ttcgcgcttg
    27841 tagaagggga agcgaaagca gaagaaaagg aaacaatgat tcatcagagt ggacgaatca
    27901 tcgaaaacgg ccctctacat ttgacgattg aaaaaaatgg taccattaca atggaagatc
    27961 gcaaaaacaa acgaaagttg aataatctgc atatttttga agatatcggc gatataggaa
    28021 atgagtatat ctttaaacaa cctttctgtg atcagccaat cctatccagt aacaaagaaa
    28081 actctgaagt aaaagtatta gtagatacac cggaaatagc aaaaataagt attctacagg
    28141 aaatggaaat ccctgtttct gcagacgagc gtttagaaaa agaacagcag atggttgtgg
    28201 aatttcgtta tcgaaaagca gaacgatcca aagaaaaacg aatccttcaa ataaaaacaa
    28261 tcatgacaat cagaaaagat agtaaaaaaa tcgactttga aacgactctc gacaatcaga
    28321 tgaaagatca tcgcttacgt gtcttgtttc ctacaaagtt acatgtggaa catcacgaag
    28381 cagatagtat ttttgaagtg gtgaagcgcc caaaccatgt gtctaaaagt tgggaaaacc
    28441 ccacgaatcc gcaacatcag caagcatttg tcaatattca tgatgaagag tacggtgtaa
    28501 cagtcggaaa ctttggtttg aatgaatatg aagtaacaga agacggacaa atcgcagtga
    28561 cgctacttcg cagtgtggga gaactaggcg attggggata ttttccaaca ccagaagcac
    28621 agtgtctagg tgagcatcgg ttcaattaca gcattgaact acatggacca gaagaaaaat
    28681 tctctactta tttgcatgca tacgcagcac agattccttt ttccactcaa caaatcaaac
    28741 atcatgaagg aacattgatt tcaaaacaac aatatttaac gataaaaagt gaaacgtttg
    28801 caattacagc tttgaaacgc agcaagttta gtgataaagt agtagtaaga ggtttcaata
    28861 tgtctagtca tttagaaaaa ttggaaataa ctaaagacaa tggaaaaact gtcatattga
    28921 atctgcttga agaaccaacg aagcaagcgg ttgtcccaat aatccaacct tatgagattc
    28981 ggacaatcgg attcgaggag gaaaacgaat gtatggcgga atagaagcag gcggaacaaa
    29041 atttgtgtgt gcggtttcag atggtggaga aattttagaa aaattaagta tccctaccac
    29101 aacaccagaa gaaacattgg atcaggtatt tgaatttttt gatcgttatg aattgaaggg
    29161 aatcgggatt ggctcattcg gcccgattgg tatcgacaaa acaaaagata attacggata
    29221 cgttttggca actcccaaaa aagggtgggc acaattcgat tttcttggca caatcaagga
    29281 acgctacaat attcctgctg cttggacaac ggatgtcaat gctgctgcat atggggaatt
    29341 gaagcaagga gcagcacaag gaaaaaatag ttgtatttac cttaccgtgg gaacaggaat
    29401 cggtgcaggt gtcgtgatca atgaagaaat tttttcaggg atcgcacatc ctgaaatggg
    29461 acatatttgg gtgaaacgcc atccagatga ccattatgaa ggtacttgtc cttatcataa
    29521 agattgttta gaaggattag cagcaggacc gtctattgag gcacgcacag ggatcaaagg
    29581 gcaagatctg ccgcaagatc atcctgtttg ggctattcag gcttattata ttgctcaagc
    29641 actgatcaac tatacgttga cgttagcacc tgaaaagatt attttaggcg gtggggtaat
    29701 gaatcaggat catctccttc aaaaaatccg tcagcaattt gttgaattga tgggtggtta
    29761 tatggaaaca cctcaagtaa gtgaatatat cgttcgttgg ggactgccga atgaaagtgg
    29821 gattatcggt agtttgctgt tagcagaaca cgaacatcaa aagtaagcag acaaattaca
    29881 caaaaagaac agagtcttat cattatctgc tgataagact ctgttct
//
LOCUS       DAKCAA010000031        29413 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000031 DAKCAA010000000
VERSION     DAKCAA010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.031"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(159..1469)
                     /locus_tag="OUE31_001518"
     CDS             complement(159..1469)
                     /locus_tag="OUE31_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HCU0222532.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDSQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1481..2899)
                     /locus_tag="OUE31_001519"
     CDS             complement(1481..2899)
                     /locus_tag="OUE31_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0222533.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3139..4707)
                     /locus_tag="OUE31_001520"
     CDS             complement(3139..4707)
                     /locus_tag="OUE31_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCU0222534.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4711..5121)
                     /locus_tag="OUE31_001521"
     CDS             complement(4711..5121)
                     /locus_tag="OUE31_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HCU0222535.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5118..6041)
                     /locus_tag="OUE31_001522"
     CDS             complement(5118..6041)
                     /locus_tag="OUE31_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HCU0222536.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6038..6916)
                     /locus_tag="OUE31_001523"
     CDS             complement(6038..6916)
                     /locus_tag="OUE31_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HCU0222537.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6903..8240)
                     /locus_tag="OUE31_001524"
     CDS             complement(6903..8240)
                     /locus_tag="OUE31_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HCU0222538.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8243..9346)
                     /locus_tag="OUE31_001525"
     CDS             complement(8243..9346)
                     /locus_tag="OUE31_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCU0222539.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9420..10928)
                     /locus_tag="OUE31_001526"
     CDS             complement(9420..10928)
                     /locus_tag="OUE31_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCU0222540.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10894..11586)
                     /locus_tag="OUE31_001527"
     CDS             complement(10894..11586)
                     /locus_tag="OUE31_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCU0222541.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11608..12582)
                     /locus_tag="OUE31_001528"
     CDS             complement(11608..12582)
                     /locus_tag="OUE31_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0222542.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12882..13754
                     /locus_tag="OUE31_001529"
     CDS             12882..13754
                     /locus_tag="OUE31_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCU0222543.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14212..16410)
                     /locus_tag="OUE31_001530"
     CDS             complement(14212..16410)
                     /locus_tag="OUE31_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222544.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16642..17634
                     /locus_tag="OUE31_001531"
     CDS             16642..17634
                     /locus_tag="OUE31_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0222545.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17694..19115
                     /locus_tag="OUE31_001532"
     CDS             17694..19115
                     /locus_tag="OUE31_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HCU0222546.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19108..20607
                     /locus_tag="OUE31_001533"
     CDS             19108..20607
                     /locus_tag="OUE31_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HCU0222547.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20646..22040
                     /gene="uxaC"
                     /locus_tag="OUE31_001534"
     CDS             20646..22040
                     /gene="uxaC"
                     /locus_tag="OUE31_001534"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HCU0222548.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22199..22882
                     /locus_tag="OUE31_001535"
     CDS             22199..22882
                     /locus_tag="OUE31_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HCU0222549.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            22884..23720
                     /locus_tag="OUE31_001536"
     CDS             22884..23720
                     /locus_tag="OUE31_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCU0222550.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23731..25485
                     /locus_tag="OUE31_001537"
     CDS             23731..25485
                     /locus_tag="OUE31_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222551.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25761..26102)
                     /locus_tag="OUE31_001538"
     CDS             complement(25761..26102)
                     /locus_tag="OUE31_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCU0222552.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26170..28341)
                     /locus_tag="OUE31_001539"
     CDS             complement(26170..28341)
                     /locus_tag="OUE31_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCU0222553.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28510..29409
                     /locus_tag="OUE31_001540"
     CDS             28510..29409
                     /locus_tag="OUE31_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCU0222554.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
BASE COUNT         8821 a         6041 c         5204 g         9347 t
ORIGIN      
        1 acgacttagt tatcttatca cgtctaaaaa catgtgtcaa ctcttttttg gaattttcat
       61 aaaatgtttc aatgaagcgc gacaacgttg tttaatatat cattaaaaaa aataaaggtc
      121 aagctaaaat attatttaag cttgacctta ttataatttc aacgattgtc aaaagtattg
      181 tttgcagctg tgttgccagt ttctatagat aaatcacagc ttttgaaaca taagttttgt
      241 actgcttcga ttcgcccgaa ttcttttgca gttatttggc aatgagaaaa gcagacatct
      301 tctataggct tttcaggaaa tgctactaaa tcaaaagctc gggaaggaag tgagtaacct
      361 ggagaaaggc atgcctgtac gtttttgatg tgtatgtctt tgactttcgt catttgcttt
      421 gattcaggta tttcttcagc cactgcttgc caactttctg gcatttgagc aaggtcattg
      481 ctattttttc tattgtattc attatgccag tccattatcc aagaaaaagg aaattgtaca
      541 tcaatcatat tcagattttc taccctgata ttttcgatca ctccccctct ttcttttgaa
      601 gatttcattc gaataccaca gtctgactga aaaaaatcga tatcgtgaat atatacgtca
      661 ctaactccag cactaacttc gctaccaata gttacaccgt atcctgaacg gattttacat
      721 ctagcaacct cgattcttga tgattttcga ttgactcttg caccattgcc atctctgcca
      781 gacttaatag caatacaatc atcaccacag gccaaatcac attcatagac acgcacattt
      841 gttgaagaat caatatcaat cccatctgta cttggtccat cattgttgcg gatgattact
      901 ttttctacta atacatcgtt agaataagtg atttgcaagt tccaaaaacc tgatttctga
      961 aaaatcaaat cacgaacaac aacatgttct gcatgataca gtaaacaagc gcgtggacgt
     1021 ttaatagcat aatccgcaat ccaacgaagt cccttttgat cgtattcagc tcttgtcccg
     1081 cttttttgat cttttcccca atacagctcc caccaatggt ctccttgact gtcgattatt
     1141 ccttttcctt ctataagaat atctttcgcc gagagaacat tcaaaatcgc tgctggccat
     1201 ttcatttcta cgccggctac tcgtgtatcg atttctggaa atgcttcgat atctgttctc
     1261 cccttgagga ctgcaccttc ttcaaagata agatgactct tatcttttaa aaaaagggct
     1321 ccgactaaat aaatgccttt tggaataaat acaggtaagt gttctttcgc accttgatcg
     1381 attgcttttt gcagtattat tgtatcatct tgttgagtgt cgtttgtttt aaagttcaaa
     1441 gcattgataa tccctttttt tgtccgcaat acgtttctcc ctatctttca ttgatttttt
     1501 tcaattcttc accaataaat acagtttttg aacgattcag tgggtaacct actagcaaaa
     1561 tgattgcgga tacaaataag cagaatgctg gtaacaagtt tgccatcgta taaatccttt
     1621 cttgtactaa aactgattgg atggctccac ctgttgtaga cgattggtaa ccaatgagtg
     1681 ccagcataaa tccgcctacc gctcctgcac atgcttgtcc tacttttctc gcaaaagaat
     1741 ttactccata tactgttcca tcttctctta agcctgtctt atattgatga taatcaatca
     1801 cgtcagtaat gaatgcccag accatcaaat tgaataaacc agatcctaaa gtagcgataa
     1861 ataaaagaat cagatatacc catgcatttg ttatatgaag gaaatacatc agcaagtaca
     1921 tacatgaaga agcaagtaac gcaaatacgc ttgcttcctt tttaccaaat aattttgtca
     1981 gctttgtagc aaatggtgct aaaactacta ctgttccgta agtaaataaa agagcaacag
     2041 acattgcttg tttattatgg aagtaatcat tgaataaata agtcatattc gtcccagcta
     2101 aaatctgatt gatcacaatg aaaatgtcaa caatgactaa aataatcagt gctcgattag
     2161 ctaacaaacc ttttaccaac tgagaagcag atactttttc gtttttgaca actcttactc
     2221 tttcagtagt caatttacaa gttaacatat atgcgacaaa tgctattgca gcacatccga
     2281 ttgaaatcca aaagaaatga ttccctgaaa cgacttgttg tccactcttg ttatgggtat
     2341 acattaaaat cggaatgaag aatcctgtag ttgatccgcc aatcgcagaa ccaatgcttc
     2401 ggaacgtgga caacgaggtg cggtcattag gatttgagct aattgctgct gccattgctc
     2461 catacgggat attgattgtt gagagaaaaa tcccataaac aatgtatgaa acaaaaatat
     2521 aagcaatctt caccgtcatt ggaagatgtt ggacgaatgg caaaaacaaa atgacagtca
     2581 ctaagcaaaa tggatacttc atttttctga tccaaggaat aaatcggcca gtttctgtta
     2641 actctgagac atcacataat cttccaacca tcacatcagc aaacgcatcc aaaattctcg
     2701 aaatcaagaa taacgtacct acgattgccc ctgaaacgcc aagaacattc gtataataaa
     2761 tcatcaagaa actattgact aaacctaaaa taaaacagtt acctagatca ccgaacatgt
     2821 agcctatctt atcggaaatc ccaaattcct ttttttcttt ttttattgta tttgctgtaa
     2881 cagcattttg tgaaagcatt tgaattcctc ctacctcttc tagtaaacgt tttcaaaatt
     2941 ataactcttt ttttcttgtt tttatattca caatgttggc tttttattgc attatcttga
     3001 cagataaaaa acaaaaaata atctaaaaac attgatgcat aagattgata acttttttta
     3061 cataacaata tatacaaaca aaaaaattca ctaactagtg aaaataagtt agtgaacctc
     3121 atttattaaa gaattaaatt acagatgatc ttttccatca tacttgaaaa actcaaaatc
     3181 agcataactt cctctttttt tatttagatc atgcactgct atcccgataa aatttccagt
     3241 aaaccctcct gagagtatac acatgttttt ttgcggacct actttcttcc attcttcagt
     3301 tgatacgtct ttcaaatgaa actgtgctgt ctctttcttt acagtgactt tcaaaaaagt
     3361 cttcttttct gtgagtggaa tcgtccaatc ttctatttgt gctactccgt tttctgattc
     3421 tatcatacgt aggcattttc ccttgtcctc attccaagta acataacaat aaatataatt
     3481 ggattcattt aagtacagta ccagtccagc catctgatta aaattattag gcatgtattc
     3541 aaatgctgtc tccgcatcaa aagtaaaatc cgtttgccga atagctaaca aatgatgttc
     3601 gaaggtagat tgaagagatt caccggaaat cagacgtaaa aaacctggtc tacattttgt
     3661 atcacaccaa tcagcatttg gcaaaatgcg tctggcattc cagttcttct ttagctctcc
     3721 ttcaaatgta tccataaact gatgatcttt ttcttgttgt acctcttcat ttgtctcaat
     3781 cattatttct tccatcggag ttgtctggct atctttaagt cttaaccaat cgtcggacgt
     3841 ccaatacact tcttgaatag cggtttctct tcccaaaata gccgcaccgt ttaatggtct
     3901 ggtacaaaga tatgtcatgt accatcttcc tgacggggtt tgtactaagc tcccatgtcc
     3961 tgtacattgc aatgtagaag caggtttgtc actagctgtc agcataggaa aaccaggatc
     4021 aagctcgtaa ggaccagtaa tattctttgc tcggcaaact gtaactgaat gtcctcttcc
     4081 tgtaccgcct tctgccgtca tcaaataata atacccgtta cgaaaataca aatgtggtgc
     4141 ctccgttttc gctaattctg tacctgcaaa tattttatag atgggaccat caagcttctt
     4201 cttctctgca tcatattctt gtaatacgat accgctggat ttattcggtg tgtccagacg
     4261 ataatcccat agttcattga caagccattt ttttcccgtt tcaagatcat ggaacaaaga
     4321 aggatcaaag ccgttactat ttaaataaat tggttcggac caaggacctg tgatctcaga
     4381 tgcagtgatc aaataattgt ggacatcttt aaacggacgg cctgcacttt tgacatctgt
     4441 gtaaacaaga taaaacaatc catcagcata actgatctgt ggcgcccata tacttccatt
     4501 tgtaggattt ccttgcaaag atacttgagt ggtcaaaata tccgttgtat gtgaccagtt
     4561 gactaaattt ttcgactcat atactcggat tcctggaagc cattcaaaag aggagacaat
     4621 aatgtaatac cgctctttca ctcttaatat attaggatct ggattgaatc ctcttaaaat
     4681 aggatttttc actttgatag tctgcatgat tcaggctcct tttctcattc ttactcgata
     4741 taaactgaat gccccagctg cgaaataaaa aaatgcaaaa ggaaacgcaa taaactgagt
     4801 gccaatcaac aatatgaatc ctgttataaa atacaaacca gtggcagttg ttaagtattt
     4861 tcctttagca gtcaaaaaca atgctactgc taaaaaagca agtgaaataa acaacacaac
     4921 ggcaaacaga ccagtcatgt cctgtaataa tccaaatgta ttttctaaag acaaagttga
     4981 atgatctaca gcaagcgact gataactttt tttaaactct gacgcagaca tattacttaa
     5041 agtaactgct aacccgccaa agaaaatcaa agatagactg ccaccgacca ttcctagcaa
     5101 tagttcccat tttcttttca tttctgaacc ccctgctttt ctaaatgtat ccattcaggt
     5161 cttttgatcg atgtttcata attgttatta cgttcagaga atttgacagt ctgttcattt
     5221 ttcttgtcat cccaattatc ccaaccagtt gggtgaacat gcccacctat cttacacgct
     5281 tcaaataaga catttgcata cggacgccac ggtcttccta aatagacgtt tctagtatca
     5341 ggttctgcag tcaaggtaca gctttcaaaa cgataccctg ttttttgatt tttcggcgta
     5401 gatgctgctg tgatgtatcc aggattttta ctggctaagc tatggatatg acactgatga
     5461 aaaacggcat ctgccccacc aaatatgaaa tccaccgttc cttcaatcca gcaatattca
     5521 taggtctgac gacaatactc aggattggca gaagccggtg tacaaaaagg agtaccatct
     5581 ttttgcaaat caggcaacgg acccgtgcat aaggtatcct gataaccaga tagtcgacag
     5641 ttttttaaag atacgcgatc tcctgaattg aataaagcaa cagcctgtcc taccttttct
     5701 cctggacctg ctgtattttc gatgtgaaga ttttctaata cgacattcga tccttctaag
     5761 aaaaaagtag cacttcggaa agtccctaac tggctaccgt caagatactc ctgttttgca
     5821 aaacgattac cggagataac tactgttcct gctcccacaa gtttaaaatt ggataatctg
     5881 ctttctatat attcatcata tcttccttct tttactatca agacctttgg atggctatcc
     5941 ggcaggcctg ccaaataatc gattccttct tggatagttt caaaatccgt cggggtatct
     6001 atagcattct ttccaattat cagtttgtct ttcatcctca taaatgctcc cttatgaatt
     6061 gtttccaaat atttctcatt tcttgtgttt ccatatgacc gcctgttaaa gaaaaagaag
     6121 aaaagttttc tggactaccc attgattgat actttttgtc cagccctttt ctcagcttca
     6181 gtacgccttc gtccaagcac atcgtatcgt tttttccaac taagctaaga cgagggcgcg
     6241 gagcgatttt ttcttggatt gctaacgttg tataagctgt caatagattt ggcacatagt
     6301 aataaaaccc atgatgatct aggcggcgat gtagcaaaag tatttcgatg tccacctgtg
     6361 ccgctagatc aatacaaact ttgacacgag aatccaatgc tgtcacccac cagcttaata
     6421 agcctcccat agaaagacca atcgttgcga gccgttgagt atctgtgtct tcccttgtct
     6481 ccaaataatc gatcaagctg atcacatcat aaatacgcat tccccataac gtttttcctg
     6541 ttaataaaaa ttgtttgaac aactcgcttt cagaaatacc tccgcgttct tcaaatcccc
     6601 aagcatcaat cgaccaaaca gcatatccca ttcctgtcag tacttctgca aaagatggag
     6661 aagctaagta aggagcacca tggatcaatt cacttttccc gactgaaaaa tctccgccgt
     6721 gagaatgcag gtaaaggacc ggcggaaacg gtccttcttt ttctggataa gcatagaggg
     6781 ctggtactgt ttccaattca tttaagtaca attgatagta ttcaagcata aaaccgtttt
     6841 gtttttctcg gtataatcgt tttccactag gggtatgtct gctagatgga gcacctaaaa
     6901 aatcattcaa ctgcataagc aaagttttta cgaacaacca gttcatccat attttctgat
     6961 tgatttgatt ggaatttctc aatactgatt tctttagtat tttctaatag aaatgctggt
     7021 ccctcgtgat tttcaatcga catctggtta aaggaaacct tacccgcaaa gccaatataa
     7081 aatccttgtc tgctcatttc ctctattcct gtcatcatag caggaacacc gggaactgca
     7141 tcttgggcca tcgagacatc gatattgtca aatgtgattt cttgtatgaa ttgttccgct
     7201 aatccataaa taaaacctgc agaagcatgg acattccttg ccgtgatatt cgaaaaatgg
     7261 atccttctga atgctggtgt ccgttcatct atcggataag cctttttttc ccatacatac
     7321 ggttctttcc ctcgcggacc acagaaataa taaagattca gtataaatgg acacatcaca
     7381 ttatccatga ctatattgga tactcgaata tcttcaacga tcccgcctcg acctcgtcta
     7441 gatttcaatc gtattcctcg atcagtttct tggaagatac aatttgaaat ggtaatatta
     7501 cgaatactac cactcatttc acttcctaat acgacaccgc catgtccatg gaccatcgtg
     7561 caatttgtga tcgtgatatt ttcgcaagcg atcctttcgt acgtatcttc agtccctgcc
     7621 ttgattgcaa tacagtcatc tcccacgtca atatggcaat tactaatacg cacatttttg
     7681 catgattctg gatcaattcc gtctgtattt ggtgaatccg ctgggttcaa gatcgtcaag
     7741 ttatcaaacg ttgcattact gcaaagaatc gggttgatcg tccaacttgg tgactggatc
     7801 aatttaatat ctttcacagt aattcgatga cagttatgga aactcatcaa tttaggacga
     7861 ggataagcga gattatctgg ttcatttcta aaagtatgcc accatttttt tccatttcca
     7921 tctaatgtac cgaaaccagt gacagagatg ttctctacat tttgagcata gatacaggaa
     7981 gcataaactt ttcgatggac tccttcccaa cgtgaatgaa caacaggata atcttttgga
     8041 tcgtcagaga atttcagaac cgctcctgcg cttaaatgaa gttcgacatt gctttttaaa
     8101 aataaagctc ctgttagaaa ttcacctgct ggaacaacta cggtcccgcc tccgtcactt
     8161 gctgcagcat caatggcttg ttgtattgct tcagtattca attcatcaat tgatgcgcca
     8221 aatgtcaaaa tatcatacat atttataatg cctccacttc aatcaatgct tgcaagaatg
     8281 caccaacgcc tttttgatca ttacaaataa ttggttcact gatgtagtaa gcatatgaac
     8341 catctcgctg atctgctccg cctaaccctg ctacttgaca gtttttattc aagttcagcc
     8401 agccttcttt tgtttccaga acaaattcat caagtaatcc ttgatgtgat ttcttcactt
     8461 gtggaagcca ttcttctttg ttcagcagtc ccaaacgtat tcctttagcc attgcgtaaa
     8521 caaacatact actgccggaa gcttccagat aatttccttt ccgttttgtt tctgttgtta
     8581 cttgatacca tgtcccgctg ttttcttctt gatatggaag taatgcagcc agtgtctttt
     8641 ctagaatttc tttcagcaaa gaacaatctg tttcttcatg aagtaattca taggtatctg
     8701 ctgcagccat caaataccag ccaatcgatc ggctccaaaa atgatgggat agacctgttt
     8761 ttggatcagc ccatggttgg accttctttt catcccatgc atgaatcagc aaatttgttt
     8821 ttggatcgaa tagatgttta taactgattt caaactgtct caaaacatct tggtaatctt
     8881 tttcttcact aaaattctgg ataaattcag cataaaaagg agaacccata tataagccat
     8941 ccaaccaaat ttgataagga taaatttctt tatgccaaaa agctccttcg gatgtgcgtg
     9001 gatggtttgc caactgctgg gaaaggagtt ctgctgcttt tttatatttt tcttcgcctg
     9061 tttctttgta caataaaaag aaaagctttc ctgtatttac atggtcgata ttgtattctt
     9121 caacgctgta gccacggatc gttccatctt cttgcacgaa atagtcgata ttgtctttta
     9181 tgaaatcaaa ataaattttt tcttgggttc gttcccaaag taattggaac cctttaagta
     9241 cgacgccata gtcataagac cattttcctt tataccactt ttcttcatat aagcgaggtg
     9301 ttctttccat gatacttttt gctaatttct ttgaccagtt ttccattatt tgctctcctt
     9361 taaaaattaa aataggattt gggacaaata ccaagaagta tttgtcccaa tcgtctatat
     9421 tactgtgccg ctgctttgta tgcttcctcg tactcttgtg tgattcgatc gcctccttgt
     9481 gctttccagt cttctacagc ttttttgaat ccatcttcgt caagctgtcc catgatgtat
     9541 tgcaccgtag catcaatgac gattttttca atttctgatc ctacttcatt gttcgtcggt
     9601 gaatccaatg gcacagaagg atccattaca gcaaattctt cattttcttt gatcaattga
     9661 ttagagaatt ctttttcagg gtctgtatct ttgaaagaga acgtcacttc actaggacga
     9721 gagcttgata acggttgcac ctcttgttgc caaagatcca tatcgataaa ttcgatagaa
     9781 ccatcatcat tcaattcata atgcgttcct tcgataccgc cagtcatcaa tttatacaca
     9841 tcttcttcta aaagatcatc aacaaattga agtaatttct tcaattgtgc ttcgtctttt
     9901 acttgagatt tgggaaatgc tagcaagccg ccaataccat ttccttctga ccaaacatga
     9961 taaccgccgc cttcaccatc tgagatcttg tttacaggca ctaattccat atcatcttga
    10021 ataccttgac ccatcgtctt cagattcttg atatccacca ttccagtgta gattccagtt
    10081 cttccttgtg caaattgttc ttgctgatca gtcttttggg taactgcaaa gtcttgtgcc
    10141 aaatagccat tctcaaatag atctcttgaa aaattcaaag ctttcatata ctcttctgta
    10201 tcaaattctg gagtgaattt gccattatcg tctacagccc agccatttgg tgctccaaaa
    10261 taagaagtga aaagtttaaa gctggtataa cgaatatcac taggcgcacg atcgccaaaa
    10321 ccaactgtgt cgtccacacc atttccatca ggatcgtttt ctgtaaattg tttagctact
    10381 tcataaagct catccatggt agttggaaca tctagtccta gattatccaa ccagtctttt
    10441 cgaatgacta agccagcacg agcgtagtct ttttgtatcg gtacgccgta caaggcaccg
    10501 tcgatactcg cagcttcgat tctatcttca gaaatttgac ttaaattttt atagtctttt
    10561 aaatattctg atacatccca gaatacgcct gattttaacg cattgcggac agaagagttt
    10621 ttcaacatcg caatttgaag tgtaacgata tctcctagtt catcagaagc caatgcagtt
    10681 gttaatcttt cttcttttga agcatcagga atccagttga atgtcagttc cgtatcggtt
    10741 ttttcttcga tcaagttcac aatcgtgtct gtaggcggtg aagcatgatg caaaatattt
    10801 aaccaagtga ttttagcttt tccatcttct gtctctgaag aactgttact tgaactgctg
    10861 ccgcatgcgg caagtgctag aattcctgca aaactaagac ctaattttac gagcgttgct
    10921 tttttcataa attttctcct tcactgtttt aataatattt ttgttttctt ctgttttttc
    10981 tgtatatgag ttcttccatt ccaaatggca aaatatagaa tttgctgtcc acgtgactgc
    11041 ggaaaagaag agactgccac cgataaaggt taaaacacct ggcattgttt ggatgatcat
    11101 cagataaatc cctaccatac ttaatatcaa cactaatgag taatgaagat gtgagaatcc
    11161 gaataaaaat gccattttca ttttgaaaaa atatcctttc caatcataat gagccatgat
    11221 tgggaaaata tagagtgctg agagcacata tatgaacgca gcaatataca aagcgatcct
    11281 aagataccaa ttgtgtatga aagaaagatc cacaagtaaa acaatcccga tggcgccata
    11341 tatccagctc atcagcaagg tttcacgata gttttcttta aaatatgtga agtacgtttt
    11401 cgtcaaagga aacgtttctt ttgagcgcag ccattttcta atcactgcaa ccatcgcata
    11461 cgatgcagga ccgaaagtaa aaactcccaa acctgcgatg actaaaccgc cccacagaaa
    11521 attcaaataa accaactgta aaatacgatt tagccttccg tttattttat ctaatgactg
    11581 cagcatatct ttccctctct ttctatctta gtaaacgccg tcttctccta gctttttggc
    11641 aatcttatta gctaaaatta ccataaacaa tcctacgacc cctttaaaca atcccattgc
    11701 tgtactgaaa cttaactgtc cattcttcaa tccagctgta taaatatagg tgtcgaaaat
    11761 ttctgcaacg cttcgattca atgaattcaa taacaagtac atatgctcga accctaagtc
    11821 taatgtctga ccgattttta gaatcagcaa ggtaatgatt actggacgaa ttgccggcaa
    11881 tgtaacatgc catgttttgc gtaagcgtcc tgctccatcc atttctgcag cttcatacaa
    11941 ctgtgtatcg actgcagtta tcgctgaaag gtagatgatc gtagaccagc ccaactcttt
    12001 ccagatcact tgtccgatat atactgtgcg tgtccattca ggggatgtta gaaaactgat
    12061 tttttcaaat cccattgttg caaggaattc attcaatacc cctccgtcaa cattcaaaaa
    12121 tacataagta atcgaaacaa tgattaccca agacatgaag tgagggatgt aaatgatcgt
    12181 ttgaatcccg tttttcaatc gtttgttcgt tacttcattt aatagtaaag acaaaatgat
    12241 tggcatcgga aaaaacacga agatatttaa tccgaacaag atcaacgtat ttcttaataa
    12301 tgtaaagaat gtcggttctg taaacaaacg aatgaaatgt ttgaaaccga cccaaggact
    12361 tcccattatt cctaaaaatg gttgataatc ttgaaaagca ataacgagtc cccccatagg
    12421 aagataccta aaaatcaaga aataaaggac tcccggcaga atcatcacat ataaaaattt
    12481 attcgttttg attcctgcaa ttattttttt tcgtcttctg agcttttctt cttttttcga
    12541 tagcgtcagt tgaaatggtt cttgtttctt tacactttcc ataagcccct ccttagtttt
    12601 gtgaatgttt gctgcttatg acttcatgat agataactat ctgaattacg tatataatca
    12661 tttttaccgt aagtaaaaac gcttacatag caatgatttt tgtgctatac aaaacgataa
    12721 agtgtatttt ttcacaaata aactacgcat agcaaacctt ctattttttt ctatctgaca
    12781 cttagcatag gaaatgatta tatacgtaat ctttcaccga tgataaattg aacatataga
    12841 aacagaaaca tttaatttat tttgaggagg agcctatcta tatgaaaaag aaagtctcta
    12901 taggagaaag aagttttaca cttttcaaca atacgtttct aattttgcta gctttgatct
    12961 gtatcgttcc ttttttaaat atcatcgcta catcttttgc ttctacacaa gaagtcgtcg
    13021 cgaaaaagtt tatccttttt cctactacct tttctttaga cgcgtatcgc tacattcttt
    13081 ctacgccgac catttttaga gcacttgctg tttcgattgg tgttacaggt gtcggaacga
    13141 tcgtcagtat gtgtgcaact tcactgatgg cctacggtct ttccagaaag tatttgtttg
    13201 gtcgaggttt cgtcaacttt cttgttgtat tttctatgtt gttcagcggg gggatgattc
    13261 caacgttctt agttgttcgt tctctagggc tggtcaattc ttactgggcc atgatcctgc
    13321 ctgtggctgt taatgcaatg aatatgatca ttatgagaaa ctttttccaa gccttgccgg
    13381 atagtttgga agaatcagca aaaatggatg gttgcacaga ttttggtgta tttttcaaaa
    13441 ttatgctgcc attagcgtta ccgtctattg ctactatctc gcttttttat gctgttactt
    13501 actggaacac ttatatgact gctattttgt atatcaacga ttcatctaaa tggccgatac
    13561 agattctttt acgccaaatc gtcattgtat caagtgggat gcaagcagaa agtagtgccg
    13621 ttgatgtgat tccaccagca caaacagtta aaatggctgt tatcgttatt gcaacagtgc
    13681 ctatgctgat tgtttatcct tttgttcaga aatattttgt caaaggagca ctcgtaggtt
    13741 ctgtcaaagg gtgattatgt actgaacgca aaatggtagt tgtgtcagaa gtggtcagct
    13801 tcaagaaata agaaggcatt tacgaaaatt gcttcttaaa tttttgtgaa atttcggctt
    13861 atttttcgaa gaatctactc ctggaacacc gtgtatcaga ggttgtgaaa gagacgttca
    13921 gccttgagcg atgataaaaa ctctcacaaa cattgcgacg agtaacccac aggagcaata
    13981 agaagcgatt ttgaaaaata gcttcccata tttcacaaaa ttatgcctta ttgtcgatag
    14041 cctgtctctt gaacgccatt tattcgtaaa aaagaactgt gacaagactt ttgtcacagt
    14101 tctttttgcg tgcttagcct tgaaatttaa ctatccataa atacaaatac tagggttatt
    14161 ctaacttctt ttattgcttg aatcagtcca caagaaaaac agcctcttga ttcacaaata
    14221 tttttttcga tattctcccg gcgtaatcga ttccttcttt ttaaagaaac gaataaaatt
    14281 ttgcggattt cgatattgca atctttctgc aatctctttt acggagaggt tagtctcttt
    14341 caaccatttt tttgctacct ctaaacgatg attttgaaca aaatcaccaa atttttctcc
    14401 tgtttccttt ttaaatacat tacttaaata gttagggtta taatgcaacc tatcagcgat
    14461 cacatctaaa gacagatcac gatcatattc tgtgtagacg atatgcataa tattctccga
    14521 caaattttta aattcatgat cagtgattgc ttgagagcat tctgtgattg gcagaactaa
    14581 ttgttctaaa acaagttttt ctagttcttt gggatgataa ttgttcagtg cttttacata
    14641 aatttgtttc atgttatcaa agttttttga atctactccc aataactgtc ctaattgaac
    14701 gagttcattg atcaagcgga ccgaaactac ttcccgactc aaaggatttt tattttgtgc
    14761 aaacaatgca tcaatcaatt catgtactaa attcttcact tcctgatttc cagaacgaat
    14821 ggcttcaaac aatcgatttt gttcttctat cggatatcta ataagtgttt tttcatgagc
    14881 agcaggaacg atttcctgat aaaaaataat tgaacttgga ccagtattta cacgataata
    14941 cagggcttct tttgcccgat caaccgattg cttgctttca ttcagcgttt cgaaccggtt
    15001 actgatgcct atactgatag ttaaattcaa gtattctttt acacgttttt gaatgagtcg
    15061 gcaatactcc atgacttttt tgcttgcttc tgcatcatct ttatccattc gataaatagt
    15121 ggcttgcatt tcttcattca aaacgatcgg cagcattcga ttttcctttg gcacaatttc
    15181 cgtgatcatg ttgttgatcg ctaaaagtag caaatcacgc tccccaccgt gactatcttc
    15241 taacagatcg atttgaacca aagctgtata atagcagtca ttttgagaac tataaccaaa
    15301 ttgctgcaac cgctgatcta gttctcgcct ttctactcga tttctaaata aactaagtac
    15361 aaatagcgtt tccagctgtg gcttttgggt aactaagtgt gcacttaacg cttctttttc
    15421 tcctatgatc cgactgactg attgagcgac caaatctagt tctttcccac tgaatccttt
    15481 tgatttaaga ttcagacgtt cctgtatttg agaaatcgga cgggcaaatc tgtccgaaaa
    15541 taagtaggaa agaagaccaa tgagtcctac cagtgttaaa gacactgcaa ctagcccgat
    15601 tctcagattg cggatcattg cgccaattgc actagagtca acttctaatc tgtaaatcca
    15661 attattataa tctgatttca gtactatata cgttttatct ttttctctta tcactttcag
    15721 ctgattgtaa tctagatcca cgtccgttaa tacagttggt tgctctttat tttttactgt
    15781 ctgagtagta aaaaggttgc caacttcgtt ttcaatagaa agtatgtctt ctccactttc
    15841 accaacaact tgttctattg tatgtttctc tatcgtagca attcccaatg catatttttc
    15901 tttttcaaac attggcaaag aaatcaccat ttcgattcct ttgtttttct tttgccaaaa
    15961 taaattattt ttgttattta tgtacttctg ttgatacttt tcaacttcct cttcggtcag
    16021 ttgactcaac gatccattga ttactcccca tttaccagcc aaactgacta aatcataatt
    16081 attatcatcc ataacaatcg tttctataaa atttagttct ttcctgattt cagaataagt
    16141 ggagtaatct gtatatgtca gcggatgctt gaatatgtcc gagaaatttt tggtcgaacc
    16201 atacgtagaa aacgaatatt caatcgttct aattttccat tcaacgttag ttttaacttg
    16261 cctgagcaaa ttctttttgt ctgttaaata actcgattcg atcgattcat aggtattctg
    16321 gtaaatgaat aaactaaatc ctatgacaag tacggctcct aataaaaaca tcggtaaaaa
    16381 tattttataa aatactgtac ttttcttcat tttcttcctc tcctcctttt aaaataaaag
    16441 gctttcattt ttctgtaaaa ttgatactca tctaattaaa tgagcattcc ccgctttcaa
    16501 gaatagcata attaaaaata aaaatccaag taatttttaa cgtgtgcaat cttttcatat
    16561 caaagatcta ttgacttatc gtagttatcg taatatgatg aatgcgttaa caaaaagtga
    16621 aaaagtaagg aaaatgatgg aatggtaacg atcaaagata tcgctaaagc agctggcgtt
    16681 tctcatacga cagtttctcg tgctttgaat aacagcagtt taataaaaaa tgaaacaaaa
    16741 caaaaaatac gacaactagc taaggaaatg aattattcgc caaactatag tgcaaaaggt
    16801 ttagtgaatc aaaaaaaata tctaatcgga ctatttttct caagtttgca taaaggaact
    16861 tcatcaaatt tcctagcaga ttccattgca ggcatccatt cagtattaga cacaaattac
    16921 agtttatctg ttgaaagtat cgatgttgtt gatttaacag aaatcaacct gcaacgctac
    16981 gatggactga tcgttatgag tcaaagtgat gatgatcagc ctttcatcga ctatctcaaa
    17041 gaaaaagaat ttcctttcgt tgttgtcaat cgtcacatca atgatccagc ggttatcaac
    17101 gtcactgccg atgatgcggc cggtgttatg caggcagtag attacggtat tggatgcgga
    17161 catacgaaga tcgcttatat tggcggaaag aaaaattttc gttcgacaaa agaacgggaa
    17221 aaaggggtat tgaaaagtct aaaaaaagcg agcatccctg tcaatccagc ctatttttta
    17281 acaggagatt acagcttaga aagcggcctc caaaacatgg aatacctatt atcactttct
    17341 gacctgccta ctctggtttt ttgcggcaac gacgacatag cgattggtgc attgagagct
    17401 gtacatttag ctggcctccg tgttccccag aacatttctc tgatcgggtt cgatgattct
    17461 ccagtcgtct cctatctcaa tccgccgctt accaccgtac gtaagccttt gaaagaaatg
    17521 tgtcaagaag gaacaaagct tttactagat ttgatcgaag gcaggacgat cgaacaatct
    17581 aaaattgagc tctccacctt gttgatcctt cgtgagtcga tcaattactt gtaaactaca
    17641 agtaatttta tataaaaatg ttaacgtgtg cataacacag aaaggaagtt tatatgaaaa
    17701 aactgacaaa agaattagtg aaaaaaaacg aagcacctgt aaaagttctt cagtttggtg
    17761 aaggcaattt tatgcgtgga tttattgatt ggcagattca gcagctgaat aaccaacaat
    17821 tgtttaaagg taatgttgca atcattcaac ctttagaaca aggtcttgga aatatgatga
    17881 accagcaaga taatttatat acggtcattt tacaaggact cagcaatggc gaaatcgttg
    17941 atacttccga gattatcacc gtagtagaac aaatgatcaa tccttatgat gaatgggatg
    18001 cttatctatc tctagcagaa aatgacgact tggcctatat cgtctccaat acaacagagg
    18061 caggaatcca attcgtggag actgataatt taacagatac tcccccacag agcctcccgg
    18121 gcaaactgac agccttttta taccgacgtt tcaaattaaa caaagctggc tttaccatca
    18181 ttccttgcga actgattgac agaaacggcg aacgtctaaa agaaatcatt ttacgctacg
    18241 cagaaaaatg ggatttagaa cctgcttttg ttgagtggtt agaaaaagaa aatgttttct
    18301 gttgtagttt agttgatcgc atcgtcccag gttatcctcg cgaagatgca ggtgttttca
    18361 atcaacggca taactatgaa gatcaattga tggtcaaagc agaaccattc atgctttggg
    18421 tgatcgaagg gcctaaagaa ttggagaatc aactaccatt caaacaggct ggcttgaatg
    18481 tcatcatcac agatgatatg actccttatc gtgaacgtaa ggtgcatttg cttaatggac
    18541 cgcatacagc gatggtccct cttgctttgt tggcggaatt ggaaactgta gaagaagtaa
    18601 tgaaagatcc tttattctcc gcatatgttg atcagttatt caatctagaa ttgattccta
    18661 tgctttcttt acctaaagat gaattagcca tttatgctga ccaaatcaaa gaacgtttct
    18721 tgaatccttt tgcccatcac aaattagaag cgatttcatt aaatagtgtt tcaaagttca
    18781 gcacccgtct gcttccagtg ttcaagaagt atatcgaaga acaaaatcag gtaccaccgt
    18841 taatcactgt ttcactagct gcgctacttc ttatgtatcg aggcgatcaa gtaaagccac
    18901 atgatgatga aaagacgata agcgaattta ctgatgcttg gtctgataat ggaacagcta
    18961 ttcctcgatt attgcaaaac gctgcgcttt ggggagaaga tttgtctcaa ataccgaatg
    19021 tgacagatac agttcaagaa atagctgcaa agatcgatca aaaaggtgtc cggtcagtat
    19081 tacaagaaat gaaaggaacg atggtccatg cttgaaaccc tgcaaccaac aatgaaatta
    19141 aatcgacgag acagtgtggt cgtcgcatta acccctattc caaaacaaac acaactgacg
    19201 attgatcagc aaacgatcac cactcttgaa gatatcccgc aaggtcataa gattgcattg
    19261 ggtgatttga aagctggaga caacgtgatc aaatatggct atccaatcgg tcatgtgacg
    19321 acagacgtaa ctgccggtca atggctgcac actcataatg taaaaaccaa tctttctggt
    19381 gaattggatt atcgatatga aaaagatgtc catccaagtc attacctttt tgagaaccga
    19441 acatttcaag gttacttgcg aaaaaatgga aaagtaggga ttcgtaatga tttgttttta
    19501 gtacctaccg ttgggtgtgt gaatggcatt gctgaactga tcgtcaaaca gttcaaggaa
    19561 aaacatccag atctgggaca gtttgaccat attacgattt taaagcatcc ttatggctgt
    19621 tcgcagcttg gaaaagatca tcaaaatact cgagaaattt tagcggacgc agtaaatcat
    19681 cccaatgccg gaggagtttt agtatttgga ttaggttgtg agaacaatac agttcctgaa
    19741 ttcaaaaaaa ttttaggtga atatgatgaa gaacgagtga aatttctagt ggctcaagat
    19801 gtttacgatg agatcgaaca aggtgtggct ctattagaag agcttttaac agcggcggaa
    19861 aatgaccagc gcatatcagt cccgctctct aagttgaatg tcggtttgaa atgcggcggt
    19921 tctgatggtc tatcgggaat aactgctaat cctttacttg gtgcattttc tgactacttg
    19981 attgctcaag gaggcagcac gatcttaaca gaagtgccag aaatgtttgg cgcagaacaa
    20041 gtattgatgg cacgagcgga aaatgaagaa gtttttgact caatcgttga cttgatcaat
    20101 gacttcaaac agtatttctt gtcttacggg gaaccagttt acgaaaaccc atctcctggt
    20161 aataaagcag gtgggatcac tacattagaa gataagtctt taggctgcac gcaaaaatca
    20221 ggaagctctc ctgtcgttga tgtgctacaa tatggcgaaa aaatcagaaa accagggctt
    20281 agtttattgc aagctcccgg gaatgatctt gtagctgcct ctgctcttgc ttcatccgat
    20341 tgccagttgg tcttgtttac cacaggaaga gggactccgt ttggctcata tgtcccaacg
    20401 gtcaaggtat ctacgaatac aactcttttt gaacgcaaag gtcattggat ggattttaat
    20461 gcaggcgtct tattagaaca accaatggaa gtaatcttag aatcgtttgt tcaaaaaatc
    20521 atcgctgtag ctagtggaga agaaacgaaa aatgaacaaa atgacgttcg agaaattgcc
    20581 atttttaaaa acggagtaac actttgattt tcataaaaca gtataaaaag aaagaaggaa
    20641 gatttatgtt tttatctgat gattttttat taaaagacga ttgggcgaaa aagctttacc
    20701 attcctacgc aaaaaacatg cccattattg attatcactg tcacttagat ccaaaagaaa
    20761 tttacgaaaa caacaatttc agcaatctga cagaagcttg gttaggaggc gatcattaca
    20821 aatggcgctt gatgcgagct tgcggcgtgc ctgaagaaaa aatcacagga aatgcttctg
    20881 attttgaaaa atttttagct tggtgtcaaa ccgtaccaaa aattatcgga aatccgcttt
    20941 acagttggtc acatcttgaa ttgaagcgtt tcttcggtat tgacttgttg ataaatgaag
    21001 aaaatgcaga gaaaatttgg acacaagcaa atgaaatttt ggcagctcct gattttcgcc
    21061 gtcgggaaat cgcaaaaaaa tcgaatgtag aagtgatttg tacaacagat gatcccgcag
    21121 acgacttgca ctatcatcag ttgcttgctc atgaagaacc agatttgaag gttctacctt
    21181 cattccgtcc agataaagca ctcaatattg aaaaagaagg atttaatgca tgggtcacac
    21241 tactggaaga agcagctgac caaacgatca ccacctatca agaactgata gaagtcttag
    21301 ggcagcggat agaatacttc catcaacatg gatgtcgtgt ttccgaccac gctttagaca
    21361 tcttacgcta taaagaagcg gatgaaacag tattagaaga gatttttcaa aaagcacgag
    21421 ctaacaaact attatcttca gatgaaatcg atgcttatcg tacagaaaca ctgatacatt
    21481 tgacccactt ctatcattct cataattgga cgatgcagct gcacatccat gcttatcgta
    21541 actgtaatac acaaatgttg gaaaaattag ggcccgatac cggctatgat ggaatgaatg
    21601 atctttcttt gactattcct ctgcaaaaat tattgaaccg tgcagaagaa acggatcagt
    21661 tgccaaagac gatcctttat tcattgaatc cgaatgacta tcctgcgatt ttagctttga
    21721 tgggctgttt ccaaaaagaa cagaatggaa aactgcagtt aggttctgga tggtggtaca
    21781 acgatactcg agctggtatg cgcgatcaat tgacacaatt tgctgatggt agtgctttgg
    21841 ggaattttgt cggcatgctg acagattcaa gaagtttcct gtcctacact agacatgaat
    21901 atttccgtcg tgttctttgt gaatttttag gcgaaatggt catgcgagga gaagcacctg
    21961 aagatgaaca acttttagga agtctagttc aagcgattag ttatacaaat gctaaaaatt
    22021 actttggctt ttttgcctaa ttgattaata gtaacagtaa cgaatcaaaa acaggatagt
    22081 gaaataacgg aatccgttta tccacgtttt agagaagaag acggaccaaa tttgctccgt
    22141 cttcttctct tgctgttctg cttcattgcc tataaacctt tatgaaagaa gagataacat
    22201 gcctactatc catattgccg gtgattctac tgcggcagaa aaagatgaaa acaagcgtcc
    22261 cgagacaggt tggggagaaa aaatctctgc ttatttttca cccgagatcc agatcaataa
    22321 ccaagcaaag aatggacgca gcaccaaatc atttatccag gaaggaaggt tagcccgtct
    22381 agcttcacag tttcagccga atgatttctt atttgtacaa tttggacata acgaccagaa
    22441 aatccaagaa gaaagaggta cgcttccctt cggtagctat ttaaaaaatc tgcagatatt
    22501 ttttgaatgc gcaaaaaaag cgaacgtcca aatggtctta ctgacatctg tgacgcgacg
    22561 agattactta gaaaacggaa cattgaatcc agatatactt ggagactatc caaaagcgat
    22621 gcgtgcattt gctgagaaac accatattcc tcttttagat gtgttctcaa gatcacaaga
    22681 attgttccag accttctcaa aagaagagac aaaaaaattc tacctgcatc ttatacctga
    22741 tacttgtaaa aattacccag aaggactaaa agacaatacc cactttagtc cagaaggcgc
    22801 tgataaagtt gcccgaataa ttgttgaatt gataaaagaa tcccgtctgc ctcttgctaa
    22861 ttatttacaa aaaggagttt gagatgtttc cattaaattt aggcatccgt gcccacgatt
    22921 tagatgttcg aaatcgtgaa gaaatcgttc aaaaagtatc acagcttcac ttgtcccata
    22981 tccaatttgc accacaaaaa gcatttcctg aacaacttaa attaactgac atgacacttg
    23041 ggagtgctgc ctattttggt gaatacttcc aaaaaaacaa tatcgaactt tccattttag
    23101 gatgctatat caacctatcc agcaaaaatc aagaagttcg tgcacaagca ttggcaactt
    23161 tcaaacagca aattgctctg tgctctgcct atcaagccaa gatgattgct acggaaaccg
    23221 gtagtgtctc tgtcggttac acaaaagaaa attttactga agaagcttat cagatcgcca
    23281 gaaattctat cattgaatta gtcgctcatg cagaaaattt tggcgtaact gttgctgttg
    23341 aagcagggat caatcatcca atctataact atcagttagc taaacgttta atcgatgaag
    23401 tagcttcacc aaatttaaaa atcattttag attgtgcgaa tttgatgcat aaagaaaatc
    23461 atgctgatca ggaaaaagtg atccgaggtg ccttggacaa tttacatggt tatattacag
    23521 cgcttcatct caaagactat atcatggaaa atggaaagat ccgcatggta cctgttggca
    23581 agggctgttt agatttccgc ccggtactgc attatatcaa atatgagcgt cctctaatgt
    23641 acgccactct tgaagctact cctgagattt atgttcctga agcaatagaa cacttgcagt
    23701 ttatttacca agattgttaa ggagaagatt atggaggaac gaatacagaa aagttatcaa
    23761 aaatatcatg caaatgcttt tcagacattg ctgcatcttt atcagggaaa ttattggcgt
    23821 tttgccatgt caggactctt ttttattatc aaacatcttc catcttggtt aatgccgatc
    23881 gctattgcca atgtaatcaa tgcagcttca tcgaaagatt cttctcagtt gcaggccatt
    23941 tatttcaacg cttttttgat ggcttgtctg attggtcaaa atatattgac gaattatttt
    24001 catgtaaaat accatagcac ttcgatccgt caagtagaag ctggactaag agcgaccctt
    24061 atcaagaaaa tccaagaact atctattcct tatcaaaaag aattgcaatc tggacgaatc
    24121 cagtcaaaga tcatccgtga tgtagaagct atccaaacgt tgtcctctca agtatttgtc
    24181 agcggattaa atatcgctgt caatttattc gtagctttag gtatcacgct ttataaaagt
    24241 cctgttgttt tcatgttttt cttattgact gttcctctcg ccgcattcgt tactctcttt
    24301 ttccgtaaaa ggatcagaca gtccaactca gacttcaggc aagaaatgga agagacttct
    24361 gcaaaagtga tcgaagtgat cgaattagca ccgattgctc gagctcatgg gttagaaaaa
    24421 cacgaaacaa ctcgcttaaa taagcatttt actcaaatct atgaaaaagg attccactta
    24481 gatatcctgc aatctgtttt cggatcagtc agctgggcta gttttcagat atttcagctg
    24541 atttgtttga ttttcactgg gatattagct ttacaagggc gcatccaacc cggcgatgtc
    24601 gtgatgtatc agacgtattt cacgacgatc gtcaattccg tttctggaat gatcacgctg
    24661 attcctacga tttcaaaagg catggaatct atcacttcta ttggcgaact gttgattgct
    24721 ggcgatgtag aaacttatca cggtaagaaa aaaatccaac atttggatgg aaattttcgt
    24781 tttgaggatg tttcttttct ttatccggac tcactcaaac cgattatcga tcatttttct
    24841 ctagaggtga aagctggaga aacaattgct tttgttgggc catctggctc tggaaaatct
    24901 acactcctta acttattgat tggatttatc cagccgactt caggaaaaat ttttctagat
    24961 gatcagcctt tggatgaact ggatatgcga agtgtgcgaa attatttagc cgttgttcct
    25021 caaaccactt tgttgttctc cgcttcgatc aaagagaaca tcacttatgg cttgaaaaac
    25081 gtatcaaaag aacgtttaga tgaagtcatc gaagctgcgc aactttcttc actgattgac
    25141 cagcttcctg atggtctgga taccttagta ggcgaacatg gcaacaagct gtctggtggc
    25201 caaaagcaac gtatctccat tgcacgagcg ttgatacgtc agccaaaaat cattttgcta
    25261 gatgaagcaa cctcagcttt agataaccag tcagagaaaa aaatccagca agccctgaat
    25321 tacctgacag aaacacccac tacttttatt gtggctcatc ggctttcaac gatcaaagag
    25381 gcagataaaa tcgttgtgat cgatgaagga aaaatcgttg aaataggtac ttacgaaaaa
    25441 ctgttagctc aaaaaggcta tttctaccgc ttgaaaaatg aatgacaaaa aataggagct
    25501 atgacaagac ttttgtcgta gctcctattt ctgaataaac ggtgttctcc tgccaactcc
    25561 tcggtcacaa gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa ttgttccttg
    25621 taactcagag ttaaacggta ggctcacgac ctcttggtaa atggtgttca agagacagcc
    25681 tatcggcaat aagaagcaat tttgtcatcg ctcaaggccg aacgtctctt tcacaccctc
    25741 tgttgtttca taaaatagtt ttattcgctg taaaggtcgc gaactggtgt catgatgata
    25801 cggttcaagt cattgatgat tgtactgaag ccttgctctt tttgcatcaa gtcattgatt
    25861 acttcttctg attggatttt cacagccatt tcttgtgctt tcattgcatc ttcgtcgctg
    25921 aactcttgtc cactcatttg tttttcttgt aattcgattt gcatcgcttg gaagtctttg
    25981 aacagtttgt gtgcttcttc gtttgcttgt actttctcgt acgcttcttt caacgctttg
    26041 aattctggta attcacggat ctcacgttcg atttgattcg cgctatcgta gatgtttgac
    26101 atgttatgcc ctcttttctt ttagtagtta ctctctattg taacatgggg ttattcgttt
    26161 tcaaaggggc tactctcctt gatatttccg ccagaggtct ttagccgctt caccaattcc
    26221 ctgaacgcct tctttcacca tatcgccgaa gtttttcagc ccttcttttg cttgttcacc
    26281 atattgattc aagttatctt gccaatttcc agactctcca ttagaatttc ctgtgtttcc
    26341 aacttgatct gcagctacca cttgtcctcc tgtggcatag gcatctgcta cactaaatcc
    26401 tgtttttgaa gtatacggaa ggatgccttc tgccgctgat ttgaagactt tcccgacaac
    26461 atttccactt gtcccttcca aatagtgcag cttgctggat tcttcgtaac ccatccatgt
    26521 cgaaatcact acgtctggcg tgtaaccgat catccattgg tcatttgctt ttgtggcatc
    26581 gaaattagtt tctgtggttc ctgttttccc tgctatcgta taacctgcag gattcgcagc
    26641 agccgctgtt ccatttgaaa atgtaccaag aagcatgctg gtcatttcat cggctgtttc
    26701 ctttgatatg acctgttttg gttttttgtt tgtgttatcg acgatcaccg ctccagtcga
    26761 atcaacgatt ttcgtgataa gatgcggcgt atacatctga ccatcattgg caaatgcact
    26821 gtaagcaccc gccatgatca atggagatac tcctttttcc agtccaccaa gggctaagcc
    26881 ataatactta tcagattttg ctaaaggcag gccgaattct tctgctttat catatccttt
    26941 ttgtaaaccg atctcatgca aaagccatac agtaggcaaa ttcaaacttt gtgcaacagc
    27001 ttgatacatc ggtacttctc cttggtatgt cccgtcaaaa ttatgcgcat cgtaataact
    27061 ttgcggttcg tctttcaaga tactggaagg cttgtatcca gcttccagtg ctggtgtata
    27121 tacgcttaat ggtttgatcg ttgatcctgg tgaacgacgc atctgtgtag caaagctgaa
    27181 tcctctaaag acatgatctc ctcttcgtcc tactagtgct tgtacaccac ctgtattcgg
    27241 atctaaagct actgaagcag attggaccat ggcaccatct gaagcatttg ctgggaataa
    27301 tgcactgttt tgataagtag cttctaattg cttttgataa tcctgatcta aagctgtata
    27361 gattttatag cctttattca tgacatcttc ttcatcaaga ccatactcgt taactgcttc
    27421 atcgatcact gcatcaaaat aataaggata acgataacca gaatctgaat tatcgtatgt
    27481 gtcattaaga tacgcgctga tatctgtctg gctttctgct tgttcttgtt cttttgtgat
    27541 ttttccgttt tcttccatta cacttagtac tgtgtttttc cgatcattcg cattttttgg
    27601 gtgatcgatc ggattataaa taccaggacc tttcagcatt cctgccaaag tagcagcctc
    27661 agacagcgta acattcgttg catctactcc aaaatacttt ctggaagcgt cttggacacc
    27721 ccataccccg ttgccaaaat aggcattgtt aagatacatg gtcaagattt cttctttgct
    27781 gtacttcttt tcgatctcga ttgccaaaaa taattccttc gcttttcgat caaacgtttg
    27841 gtctaatgtc agatacgcat ttttggcaag ctgctgagtg atcgtacttc ctccgccccc
    27901 tgatgttccg ccagacaaga ccattcggac tgctgcacgg gcaatccctt tgatatcaaa
    27961 cccgtgatgc tcgtaaaaat tcctatcttc tgtcgagatt actgcatctt ggatataggg
    28021 agaaatcgcg tttaattcta catatgttcc tttttgggcg tacagtgtgc cagcttcttc
    28081 gtttttctta tcataaatga ctgtcgattg gcttaatcct gattttaacg tttcgacatt
    28141 tgcttgtttt gctaaaataa agaggtagat acttgtcact aagacacaga tcaaaccaat
    28201 cagcaaaatc aatttgttca catgatattt tttccagatg cgctttcgcc atcgatggaa
    28261 ttgtccgaga tatggtctga tccaacgcca aaaactgatc aaagcagctt ttatcttttc
    28321 taaaatgctt tgaaaatcca tttgcttctt ctcctgtcta tttgattcaa tcgtcttatt
    28381 ttaccatagt gaaagagtgt tttcttcctg cttaagttgt agttcaatat gtttttttac
    28441 gttagtgcaa gtagagtaac ataagaatga acagaaaaat gtaagttttt tcttaaatat
    28501 gttttaaaaa tggtacaatt agtctgcgat tgcactgaaa ggagtacact tgtgaaaatc
    28561 acgatcactt tacctatgaa ccatcctgaa acaacaattc gcgacttgct tgaaaaggaa
    28621 tggttagttc ctagaaaggt tcgacacttt ttgcgtatac gtaaaaacgt ttggatcaat
    28681 caacaacctg ctttgttcca tcatgaagta aagggcaatg accagatcac attgttattc
    28741 gaagaaacag attataatta tcaagaagtt caattaggag atgcgaagca catccgtgtt
    28801 ttatatgaag atgagcattt gattatagtg gataagcctg caggaatgaa gactcatcca
    28861 aatgaaccga cagaaaacag taccttactc aatcatttag ctgcttatct cgacactaaa
    28921 cagcaacgac cttacgttgt ccaccgcttg gacaaagaaa caagcggtgc cgttttattt
    28981 gcaaaaaatc catttgtctt gccgatactt ggaagaatgt tggaacaaaa aatgatctat
    29041 cggagatatc aagccatcgt atggggagaa attgccaaag atatgaccat caccaataaa
    29101 attggacgag atcgccatga tcggagaaaa agggtcgtag atgataaaaa tggtcagagc
    29161 gccttgacac atgtcactgt caacaaagta ctttctgaac aaacacaagt ctattgtgtt
    29221 ttggaaaccg gacgtacaca ccagatcaga gttcatttag ctcataaggg acatccgatc
    29281 gttggagacc ctctctacca aaatagaaca gctgaacgac tgatgctcca tgcattagaa
    29341 ctgcacatga tccatccatt tactcaagaa aaaatagtcg gtaaagcttt acctggatta
    29401 tgggaataga aat
//
LOCUS       DAKCAA010000032        29109 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000032 DAKCAA010000000
VERSION     DAKCAA010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29109
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.032"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..1030)
                     /locus_tag="OUE31_001541"
     CDS             complement(<1..1030)
                     /locus_tag="OUE31_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0222555.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="OUE31_001542"
     CDS             complement(1112..1801)
                     /locus_tag="OUE31_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCU0222556.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="OUE31_001543"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="OUE31_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HCU0222557.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="OUE31_001544"
     CDS             complement(2328..2831)
                     /locus_tag="OUE31_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HCU0222558.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="OUE31_001545"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="OUE31_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HCU0222559.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="OUE31_001546"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="OUE31_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HCU0222560.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="OUE31_001547"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="OUE31_001547"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HCU0222561.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="OUE31_001548"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="OUE31_001548"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HCU0222562.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="OUE31_001549"
     CDS             complement(6443..7462)
                     /locus_tag="OUE31_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCU0222563.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="OUE31_001550"
     CDS             complement(7635..8540)
                     /locus_tag="OUE31_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCU0222564.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="OUE31_001551"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="OUE31_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HCU0222565.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="OUE31_001552"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="OUE31_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HCU0222566.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="OUE31_001553"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="OUE31_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCU0222567.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="OUE31_001554"
     CDS             9753..10397
                     /locus_tag="OUE31_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCU0222568.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="OUE31_001555"
     CDS             complement(10453..10956)
                     /locus_tag="OUE31_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCU0222569.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="OUE31_001556"
     CDS             11553..12518
                     /locus_tag="OUE31_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCU0222570.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="OUE31_001557"
     CDS             complement(12617..13789)
                     /locus_tag="OUE31_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222571.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="OUE31_001558"
     CDS             complement(13776..14921)
                     /locus_tag="OUE31_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222572.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="OUE31_001559"
     CDS             complement(14935..15867)
                     /locus_tag="OUE31_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222573.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="OUE31_001560"
     CDS             15984..17063
                     /locus_tag="OUE31_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCU0222574.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="OUE31_001561"
     CDS             17060..17689
                     /locus_tag="OUE31_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0222575.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="OUE31_001562"
     CDS             complement(17799..18026)
                     /locus_tag="OUE31_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCU0222576.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="OUE31_001563"
     CDS             complement(18129..20717)
                     /locus_tag="OUE31_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HCU0222577.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="OUE31_001564"
     CDS             complement(20737..21396)
                     /locus_tag="OUE31_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCU0222578.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="OUE31_001565"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="OUE31_001565"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HCU0222579.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="OUE31_001566"
     CDS             complement(22169..23035)
                     /locus_tag="OUE31_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCU0222580.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="OUE31_001567"
     CDS             23144..23785
                     /locus_tag="OUE31_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HCU0222581.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="OUE31_001568"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="OUE31_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HCU0222582.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="OUE31_001569"
     CDS             complement(25226..26125)
                     /locus_tag="OUE31_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCU0222583.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="OUE31_001570"
     CDS             complement(26127..26924)
                     /locus_tag="OUE31_001570"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HCU0222584.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="OUE31_001571"
     CDS             complement(26902..27606)
                     /locus_tag="OUE31_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HCU0222585.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="OUE31_001572"
     CDS             27737..28312
                     /locus_tag="OUE31_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HCU0222586.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="OUE31_001573"
     CDS             28430..29107
                     /locus_tag="OUE31_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCU0222587.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8565 a         6169 c         5232 g         9143 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaaaa
//
LOCUS       DAKCAA010000033        27515 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000033 DAKCAA010000000
VERSION     DAKCAA010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27515
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.033"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..660
                     /locus_tag="OUE31_001574"
     CDS             <1..660
                     /locus_tag="OUE31_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0222588.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIREWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
     gene            822..1010
                     /locus_tag="OUE31_001575"
                     /pseudo
     CDS             822..1010
                     /locus_tag="OUE31_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
     gene            1287..3347
                     /locus_tag="OUE31_001576"
     CDS             1287..3347
                     /locus_tag="OUE31_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HCU0222589.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            3430..3999
                     /locus_tag="OUE31_001577"
     CDS             3430..3999
                     /locus_tag="OUE31_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0222590.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4174..4980)
                     /locus_tag="OUE31_001578"
     CDS             complement(4174..4980)
                     /locus_tag="OUE31_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222591.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5118..6632
                     /locus_tag="OUE31_001579"
     CDS             5118..6632
                     /locus_tag="OUE31_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HCU0222592.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(7035..8018)
                     /locus_tag="OUE31_001580"
     CDS             complement(7035..8018)
                     /locus_tag="OUE31_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HCU0222593.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(8023..8670)
                     /locus_tag="OUE31_001581"
     CDS             complement(8023..8670)
                     /locus_tag="OUE31_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCU0222594.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(8755..9387)
                     /locus_tag="OUE31_001582"
     CDS             complement(8755..9387)
                     /locus_tag="OUE31_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCU0222595.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(9403..9954)
                     /gene="coaC"
                     /locus_tag="OUE31_001583"
     CDS             complement(9403..9954)
                     /gene="coaC"
                     /locus_tag="OUE31_001583"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HCU0222596.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(9951..10688)
                     /locus_tag="OUE31_001584"
     CDS             complement(9951..10688)
                     /locus_tag="OUE31_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HCU0222597.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(10685..11674)
                     /locus_tag="OUE31_001585"
     CDS             complement(10685..11674)
                     /locus_tag="OUE31_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCU0222598.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            11932..12474
                     /locus_tag="OUE31_001586"
     CDS             11932..12474
                     /locus_tag="OUE31_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0222599.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            12491..13576
                     /locus_tag="OUE31_001587"
     CDS             12491..13576
                     /locus_tag="OUE31_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222600.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            13588..14394
                     /locus_tag="OUE31_001588"
     CDS             13588..14394
                     /locus_tag="OUE31_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222601.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            14395..15222
                     /locus_tag="OUE31_001589"
     CDS             14395..15222
                     /locus_tag="OUE31_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222602.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            15219..16292
                     /locus_tag="OUE31_001590"
     CDS             15219..16292
                     /locus_tag="OUE31_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCU0222603.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            16720..19416
                     /locus_tag="OUE31_001591"
     CDS             16720..19416
                     /locus_tag="OUE31_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCU0222604.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            19493..19981
                     /locus_tag="OUE31_001592"
     CDS             19493..19981
                     /locus_tag="OUE31_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0222605.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            19993..20487
                     /locus_tag="OUE31_001593"
     CDS             19993..20487
                     /locus_tag="OUE31_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0222606.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            20508..21317
                     /locus_tag="OUE31_001594"
     CDS             20508..21317
                     /locus_tag="OUE31_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCU0222607.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            21314..22135
                     /locus_tag="OUE31_001595"
     CDS             21314..22135
                     /locus_tag="OUE31_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCU0222608.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            22186..24285
                     /locus_tag="OUE31_001596"
     CDS             22186..24285
                     /locus_tag="OUE31_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HCU0222609.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            24282..25400
                     /locus_tag="OUE31_001597"
     CDS             24282..25400
                     /locus_tag="OUE31_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HCU0222610.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            25439..26317
                     /locus_tag="OUE31_001598"
     CDS             25439..26317
                     /locus_tag="OUE31_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCU0222611.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            26508..26660
                     /locus_tag="OUE31_001599"
     CDS             26508..26660
                     /locus_tag="OUE31_001599"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCU0222612.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         8783 a         4732 c         5744 g         8256 t
ORIGIN      
        1 tatatttctt tgttatgcaa agaagaagtt cgcgaactac ctaaatctaa ttctgctgtt
       61 ggtattgacc taggtattat agactttgca attctttctg atggacaaaa aattgataat
      121 aataaattta cgtccaaaat ggaaaagaaa ctcaaacgtg aacaacgtaa gttgtcaaga
      181 cgtgccttat tagctaaaca aaaaggtatc aatctgtttg aagctagaaa ttatcaaaca
      241 caaaaacgta aagtagcacg attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat tatcaaaaat cacgatatca tctgtattga agacttaaac
      361 acaaaaggca tgttgcgtaa tcataaacta gcaaaaagta tttcggatgt ttcttggtct
      421 agttttgtgt ctaaattaca atacaaggct gactggtacg gtcggaaaat catcaaagta
      481 gataagtggt ttccatctag ccaaatctgt tcgaattgtg gacataaaga cggcaagaaa
      541 tctctcgaaa ttcgagaatg gacttgccct atttgtcata ctcatcatga ccgagatatc
      601 aacgctagta tcaatatcct gaccgaaggt ctaaggctac actctatggg attggcttag
      661 atcaaataaa caagaaccgt aggaactacg gggatagctt ggtaaataag aggcacctct
      721 gttagtaaag taatacgcta tcaagtatgc tctcttccca agaagctccc acttcaagcg
      781 taagaaaccg ttaggtttag ctaagtggtg agtagttcac aaattacaat attgtgattg
      841 agagtcgaat cacttctcgt acgaatattt atttatctga ttgtttactt gaaaaattta
      901 ataaagaaca gataatttgg aaaaatccac cgactccaga tgactgggaa tattttggaa
      961 ataccatcat cagagaaaaa aatagacatt taactgaaaa aatcagctag tatttatgga
     1021 tggcagcttt gtctcacata tttattagct gatttatgtt tttttcaaag aaaaggtaac
     1081 tagatataac tagatataac tagatatatt acttaacaaa attaaaaagt acataagtta
     1141 ttattccgat tttcttgaaa caataaaaaa tcaaaaaaaa tactctccta atagtccatc
     1201 ttcttttgat tttatttata taatgaaatc atcttatgaa aattactact tcatgtttag
     1261 acaagagtag ggaggactaa gaataaatgt gttcaaaaag acgttcaaaa caactaaata
     1321 aacacgcttg tcgtttagat aaggaacggt cgtgttctga aaaacactac gttaagttta
     1381 tgatgcgcac gatgctgatc agtttatctg taggtgtcta tatgcatgta cccgttcagg
     1441 caacgacaca aaccatcaag gtcgtacgta cctctgtttc tgagaccact gattccccta
     1501 tcactattac tcatactttc actgatgcaa atggaaaaca gctacttcct gcattgactt
     1561 cctataataa agtcagttat cctccaacga taaaccacta ctggttaatt cctaacaaaa
     1621 cattatggac atcggaaacc ggaagcagtg tgccgctttc tatcttttcc gatatgactg
     1681 atcctacaaa aggtgatcag ttaaaacaga tcactgatat tttgaatcat gctttgacag
     1741 atataaagga cggtggaagc gcacaagttt cttatgtata tgaaaaagat tattcacagt
     1801 ttgaaagaaa gaaaatcgat gttctggcag ggacaaaagt ttcgatatct gatctggtag
     1861 aaaggctgaa gaacgcagat ggaacacaag gagatatgtc caaagtaatt tcaaacaatg
     1921 ggaatatcgt ggatacgact aatacaggaa catctactat ttccttgtcc tattttgatc
     1981 caattgcttt aaaaacaatg actgcatctg ctgtgatcca tgttcgtgct gatcaaacag
     2041 ctatcaaagg aaaagatctt cacttaagaa caggagagag ttacgcccct aaagatcttg
     2101 ttgaatatgt aacaaaaagc gatggaactt caggaaataa agaagaaatc aaaatgaacg
     2161 ggacagtaga tactacaact ccgggagaat atcccgttgt attaacttat atagactcga
     2221 aaacatcaaa tgtggcagaa acaacagctg tagtttatgt agaagcatct gctgcttcat
     2281 cgactgtcat cactcatttt atagatagtc aaacaaataa agaacttcaa gcagaaacac
     2341 atatgagtag tgtaaatcgt attcctgatt tgcgcctacc tgctgaattt tctgatcgag
     2401 tgccaaatat agatttatcg acttatgaac aaaatgggaa agtcacttct atttctgatt
     2461 ggatgcaagc aaacggatta gacagaaaaa gtcactggtc ggagatcctt gaagtacttc
     2521 actcagaact gatgaataat aggaagcaat caggagggga aattaccttt acttatgttt
     2581 atataccaga caatcgttca ttagaaggtc atgatcttat tgttcatcca aacgaaaaaa
     2641 taaacaaaga agagttgatc caatcagcaa caaattcctt aggtaaaccc gtaccgttaa
     2701 aggatgtatc ggttacaatc aatgaagtac cattggagga tggttatttg accaaacaaa
     2761 caggtgattt tacgattatg tatagttatc atgacccgta ttcactccaa gaactccatg
     2821 ctcagtcact attacatgtt ttaccattaa acaaacagat agatcaaaaa gaacaaaaaa
     2881 gacaagaaga aagcttgtca gaaaaaaaac aacaaatggc ccatgcagtt tctccaacag
     2941 ggaaagtaaa acaaacaaga agcctagagt tagcaagaat atctagaaaa atctcagaat
     3001 ctaataaaac gataaggcaa gaagctcatt tggccccaca agtttctgga ttggaaaatg
     3061 aaattttaga gcctaaaata aaacaacaat cagaaaaaga atttgttgct aaacagtcgg
     3121 aagatcagaa ggaatcagat gaccagaagg aaacgaagaa aaaacgcttg tcaactattg
     3181 attccaccga tgagcatctg cagccgcaag taccacttcc tagtccggga acacccgcac
     3241 ctggtggagg tattccttct tctgctttag gagatttcat gcgaggtatg gcaggaacat
     3301 gggtatacgc taatcgaaat gaatttgacg cagatgactg gttctgattt atatctctat
     3361 ctgttatagt caaataagta gctgagtcat atgttatttg gcataatgga gacgaggagg
     3421 gatagaaaaa tgttagataa aacgttacct tacgcagaaa tctggatgac aagaccactt
     3481 caacaaaatg ttccaatcac gcctttagcg gaaggttttg aatttcgatt ttatcaaaaa
     3541 gaagatgaat ctgcttgggc ggagattgag acttccgttg gggaatttca aacgacagat
     3601 gaagcacttg agtattttca acaaaacttt gctccttatc ctgaagaact tgaaagaagg
     3661 atgttttttg tagagacaaa aaaaggagaa aaagtagcaa cctgtaccgc ttggcgaaaa
     3721 aaatcaagag agcaagtgta tccggttttt cattggttag cagtgaaacc agattaccaa
     3781 ggaaaagggc tcgcaaaagc attgactgcc agagtcttgc aagaatttcc taccctccat
     3841 acggacggac caatctatct tcacacacag acatggagcc atcaggcgat tgctctttat
     3901 aaaaaaatgg gttttacttt tattgctgaa aatctagacg gcacacctaa tccagattat
     3961 gaaaaagtta tgcaggtttt aagtaaatta gataaataac gaaatggtga aataagtcct
     4021 cagtattggg ataaaaaacg aaatagtcat tcctcatatc ttactttttt gagttaatac
     4081 tatcggataa ctaatggcat gccatacatt caaaaaagaa ggggcagtga caaaagtatt
     4141 gtcactgccc cttctcttgt tttttagcat gttttatcgt ttgatttttt taggaataaa
     4201 attcttgatg aacgtaaatt tttggtaatc gtttcgacta tagaggtaac caaatacact
     4261 gaaaacaact gctccaataa aattaacaaa taaatccttc atagtatcca tgattcccac
     4321 gtctaagtaa ccattttgga tgattgtttt atctgtttta ccatctgcat tttgactttc
     4381 aatgattgtc cgagtgatat ctggaacatg atagacagtg tttccgtctt tacttaactc
     4441 cacactattg atttgctgga tgatcgtatc tttttgcata tcgaattgca gtaatttatc
     4501 tgctgaaaat tccacaaact cccacataac accaactgtc atcgaaaaac agaaggaaac
     4561 aactgctagt aataaaggag tcaagttcat ggtttttgta tttttattga gcaaataaac
     4621 aagggaaaag ccgacacccc cagctaaaaa tccgctgaat gcatgtagaa aagtatccca
     4681 cattgaaaaa tagccataaa aatcacttaa ctctcctaaa actgttgaac taaaaataaa
     4741 agataacaaa atgatttcta gcatatttgg aatctgtatc tttaatatct tttccagaaa
     4801 ataagggatt tcaaataaaa ttaatgtcag taataaaagc attgtatttc cccagtgttg
     4861 gttccagacc tgatccacta gcataataac gacgatgata cgtaataaaa tatagattcc
     4921 gtttgtgatt ctacctgcag tttttgtact gttcgtaaaa aaggttttca aatgattcat
     4981 aaaataactc cttcatgtat atccttaatt atactaagaa gcgtgtgttt accaaagcta
     5041 tatgacttaa agaaaaacag agttgatatt gtgaaaaaaa tcacttaata tagtataagg
     5101 agaaaagggg gatacaaatg aaaaaattag ttgctggttt attaacagcc gttgcacttc
     5161 ttgctatgag cgcatgcggc gcagatcaga aaaatacagc gcagacaagt tctagtacga
     5221 aggaatctgc cgaagtatca tcaggcgctt ctgaacaagt atatacagat ccaaaagaaa
     5281 tgaaagaatc ttatgatgtc gtgattattg gagctggtgg tgcagggatg gcagcagcta
     5341 tcgaagcaaa agatgctggg ttgaatccag taattttgga aaagatgcct gttgccggag
     5401 gaaacacatc taaatcatca agcggtatga atgcttcaga aacaaaattt caaaaagaag
     5461 aaggaatcaa agactcgaat gatgccttct atgaagaaac gctaaaaggt ggtggaggaa
     5521 cgaatgataa agaaatgctt cgatactttg tcgatcactc tgctgatgcg gtcgattggc
     5581 tagatcaaaa cggtatcaaa ctggacaact taacgatcac tggagggatg agtgaaaaga
     5641 ggacacatcg tccgtctgat ggctcggcta ttggtggata cttagtggag gggttattga
     5701 ataacgtcca tgagcgggaa atccctattt ttgtcaacgc agatgtgaca gacattaaga
     5761 aaaatgggga aacggtcaat gaagtgactg tacatgttca aggagaagaa ccaaaagagg
     5821 tcaccggaaa agcaatcgta gttaccacag gcggttttgg tgccagcaaa gaatttattg
     5881 aaaaatatcg tcccgattta gctgattata ttacgacaaa tcaagaagga tcaactggag
     5941 atggtatcac catgattgaa aaattaggtg gacaaaccgt tgatatggat aaaatacaaa
     6001 ttcatccaac tgtgcagcag gatgaggggg tcttgattgg tgaggttgtt cgcggagaag
     6061 gagcaatctt ggtcgatcaa gaggggaaaa gatttgtcaa tgaaatggat acaagggata
     6121 aagtatctgc agcaattaca gcattgcctg aaaaatcagc ttatttgatt tttgaccaag
     6181 gcgtgcgtga tcgtgccaca gctattgaat tttatgacca aaaaggatat gtcacaactg
     6241 gaaagacaat ggaagaatta gcagaaaaaa tcgatttacc aaaagaaaca ctagcaaaaa
     6301 cagttgatgg atggaatacg gatgttgcgg agaaaaaaga tgctcaattc aaccgtgcca
     6361 cagccatgga acatgactta tcgtctccga attattatgc gatcaaaatc gcaccaggaa
     6421 tccattacac gatgggcggt gtgaaaatca atacgaacac tgaagtatta gataaagaaa
     6481 accagccaat tagggggtta tatgctgctg gtgaagtcac aggtggctta catggaaaca
     6541 accggatcgg tggaaattca gttgcggaga tcattatttt tgggcgacaa gcgggcatac
     6601 aagcagctcg atttgcttcg gaaaatgaat gaaatagaac gtaaataaaa agaggttgtg
     6661 aaatcagcgt tttgagctaa taccgagggt cagctgattg aacactgttt agtgaagagg
     6721 ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc aagtaaaaac agcttcttat
     6781 gtttttaact tggttggact tattaccgca gatgcaagct tttgaacacc gtttattcgg
     6841 aaaaagagcg tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa
     6901 cggcggaagc agaagaaatt ccttcggaaa taagctgaaa ttcacaaaaa tttgaaaagc
     6961 aattttcgtg aatttcttct tatttcttgg agttaaacgc ttctgtccca gcctcttttt
     7021 tgatcagcat gattttattc agttatcttc aaaatgattt ttccgatgtt tttgtttgct
     7081 tccatatatt catgcgcttg tttgactgcg ctgaattgga atgtacggtc aatgattggc
     7141 cgaatcttgc cattttctag aaaaggccca gctttttgca taaaagtttg tgcgagctct
     7201 gctttatact gatcacttct aggtgtcaat aatgtaccaa gcagttggac acgtttccca
     7261 atcaatacac caaggtctat ctcaggcacg atggtcccac ctagcatacc aatcaagacc
     7321 caacgtccat caacggctat agaagctaaa ttcttttccc agtaagaagc gccgatgaaa
     7381 tccaaaataa catcgactcc ccgaccttca gtgatttttc gtacctcttc ttgaaagtct
     7441 tgttttttat agttgatcaa ttcatctgca ccaagttctt tacaaaaggc gagtttttct
     7501 tctgatcctg cagtaacgat gattttcgcg tgagaaagct gtctagctaa ttggatcgct
     7561 gctgttccca caccacttgc tcctgcatgg atcaagacag tttcgccttc ttgtaatttt
     7621 ccaagccagt aaagtgtttg ataagcagtc aaaaaaactt ctgagattcc agcagcagaa
     7681 acatagtcta gcgtatcagg gagaaggatt gcacgatcgg caggcatcac agcatattcg
     7741 gcataaccac ctagattgac taatccgtat acttttgtcc caggagtaaa agtggagata
     7801 tcacttttat tctcaactac ctctccagct acttcgactc ccaaaatagg gtagggaggt
     7861 ttcaaagaga ctgattctct tttcataata tctgttcgat tgacagctgc tgtatggact
     7921 ttgatcagta attcgccttg ttttggttta ggaacaggca cttcaatttg ttctaataca
     7981 tctacagaac caggatgctt gattgaaatg gcacgcatgg atctattcct cctttgccca
     8041 ttcttggaat gctgtattca actctttgct accttcagaa agtactagag tcgtacgaga
     8101 aatatccgtt tcttccacta gagcggcaag tacagcagca actgtagagc gagtgatcgt
     8161 ttttgatgcc ttctcattag gcttagttaa ttgaatggaa gtaacttctt catcgttagt
     8221 caatgtgact ggttgaagaa tgacaaaatc taagttagtt cgtttcagcc attcatctgc
     8281 ataatgttta gtaatataat aatctgtcat ggactcaggc cattttgctg gttcatctgc
     8341 ataaacagca ctgaccatca gatagcgaga gacatgcgca ttttcagctg cgatcactgt
     8401 tttgattgcg ccatccaagt ctacttgcag aagattcttt ccttgagagc cggcagcaaa
     8461 aatcaataca tcgatgcctt tgaatgcttc ggtcattttt tccacggacc aagttaaatc
     8521 aaaagagaca tacgaaacat tctctttttt tactaatgtt tgggaagcaa catctctcac
     8581 ccctgcaaaa atttcatggg aacttggagc taaatctttt atcaggtgtc ggccaatttg
     8641 tccgtttgca cctacaacaa aaattttcat ttggatcatc ctttcgacgt caaatctttc
     8701 cattcaatag taacaccaaa agagaaaaaa atcagagatc ggctacgatg actatcagtt
     8761 agtaagagaa gggtgcttga agtatcttaa caagacattg catactgctg cagtcgcaag
     8821 acctgcgacg attccttcag gtataccact tgtaaaaata accgctagaa tagctgaata
     8881 aacagcattt aaatttgttc cgatgacttt ggcataatct tgctggaata aaaagtagat
     8941 catattcatc actaaaatcg tattggtcaa tgaaccggaa agtccagcta agaataaaga
     9001 aacggaatct gctttttgtt tcattagttt gcgcagacct ttataaacga aataaggaac
     9061 caccccaatc aagatgcgag gaataaacgc gatcagcaag gctttccagc ttccatgttc
     9121 tgttccgatg actgggataa acggagaaaa gacaaaagac aaaggtgttt ggataactgt
     9181 gctacggatc atgctgatca gtccaaatgt accgccaaga aaagcaccta gtcttggtcc
     9241 taaaacgatc gaagcaatga ttacaggaat atgcatggtt gttgcattga ttggaccgat
     9301 agggataaaa cctaaaggcg taacagctaa taaaatcaaa atagctaaaa acatcgcagt
     9361 taatgtaaag ttttttgtat ttttcataag tactcctttt ttctaagcat ttctttcatt
     9421 aagagtcagc atgacctgtt cgatgatcgt ctgaatatca gctaaggcac cttttccaaa
     9481 atctccacaa gctaaaagag attctcttgg ttcaatttcc tgatagccga cagatctcaa
     9541 tgtttccaga ttacgctgag tgatcgggtt ttgatacata ttcgtgttca tggcaggggc
     9601 aatcaatttt ggtgttccca ctggaagcgc cattgcgact gttgaaagaa gatcgtctgc
     9661 aatgccgttt gctagcttgc cgataatgtt tgctgtagca ggcgcgatga gaaacaagtc
     9721 agcttgtttt gctagttcga tatgattgat tacctgcgga tttgattctt gcatgacgtc
     9781 tgtatggact gcgcgcttcg acagagattg caaggttaat ggcgtgataa aatgtgtgct
     9841 gcttttagac ataatcacat ctacctgggc acctaatttg acgaattgac ttgtaagatc
     9901 agcgcttttg taagcagaaa tacttccagt aacgcctagt aagatctttt tcattttgat
     9961 tcctccagtc taattttctc agtaatcaat gcagcaatct cagatttact ttgagcttct
    10021 tccactgttc catctttaga taagagatag ccgtggtgtg tctcgccatg gatttccgtc
    10081 aaatcatttg cgaaaataaa atcagttttg ttatttatca gactattttt tgcgactgcc
    10141 agaagagatt cctttggtac atctactaat agtttgaaac caatgatttt tgcttttggc
    10201 tgccattcac gtagataaga aatgattttt ggtgttttct tcaaaacgag cacaagatgc
    10261 tcggtgttag aagagatctt tgaaacagtg gtatctgtct gttcattttc cgcaaaccaa
    10321 ttgtccagtt cttcttgcgt tgaagaagtg ggtaggtttt ttgccagctg ttcttctgaa
    10381 aaactaaaag caggagtaaa atcactgact gccatactgt ggataatcgc atcgtagtgt
    10441 tcttttttcg ttagttcttc taattgtaaa aataagtcca gtgcagattc gatcgtataa
    10501 atcgttatat tggagtgtct tttcggtttc agtgcttgtt tcgtagtcac gtaatcgatt
    10561 gtggtatccg gattggcagc taaataatca gctaatgctt gccctaatcg tcctgtcgaa
    10621 tgatttgtaa tagcacgtac ttgatcgatt ttttcagtcg ttcctccagc tgtgattaga
    10681 atcttcattt atggtcacct acatttacta gtgttcttcc ttggtgtgtt ccagcaagta
    10741 gtttagatgc tgtttcaggc aattgatcca gagtaatctc ttggacgacc agttcatctg
    10801 caatctgcaa atccgccatc tgttgccata aagaaagacg ttgatctatt ggtacattga
    10861 cagaatcaat tccaatcaac tggatgtttc gcagaataaa aggcaagaca gtcgcgttta
    10921 gtttgattcc cccagcattg ccacataaag ctactgcacc gttataagag atcaatggaa
    10981 gaagactgct tagctgctcg ccacctactg tgtcgatgac atagtcgatt tgctgttttc
    11041 ctaaagcttt tgttgtctct ggcagaaatt catcaggtcg tacgacttgc aaagcaccta
    11101 gactttttag ccatgtgaca gactcttctt ttctggaaaa ggcaatgatt gactggaatc
    11161 ctagtttatg taacagggct atcgctgtac tgcctacacc gccagaagca ccagtaacga
    11221 caactttttt atcggaggtc ataccttgac ggattaaagc gttcacacac aacatagcag
    11281 taaaccctgc tgtaccaagg atcatcgctt gacgcagcgt catatttttt ggtagaggaa
    11341 ctaaccagtc tcctggtact ttttgatatt ggctataacc gcctggatgg gtgacgccaa
    11401 gcccaaaacc agtagcaagt acaagatctt cttttgaaaa acgtggattg ttactttgga
    11461 cgacagttcc ggataaatca atccctggag tcatcggata tgttcgtatc acctgaccag
    11521 actcgctcat tgccaatgca tctttataat tgacatcaga ataggcaatt tttaccaaga
    11581 cttcattttc agccaactca gtaaatggca gatcactgat tgctgtatgg aaaacaggtt
    11641 cctttattac ctgaaaagat cgaaaagcgt tcattcgtga gacactcctt ttaaaatttt
    11701 cttttatcat accataaagc ctactctttt attcttgttc ttccgtaaat ttagacaaaa
    11761 attaggtgaa aaataaagaa tcaaacaact agaatttatt ccaaaagata aagaaatatt
    11821 cagcaaaaaa aattttacaa atggttgcct ttttcaataa atttcgtata ctaatacgag
    11881 tggtagtaaa caggaagttt actattagaa aacttcgatt cggaggaaat tatggaaatt
    11941 ggtgagaagt taagaaattt gcgcatccaa aagaatttga cacaagaaga actaggcgaa
    12001 cgcacagatt tgtcaaaagg gtatatttcc cagttggaac gagatttaag ttcaccatca
    12061 atggaaacat tcttttctat tcttgaagtc ttaggtgtga ctccagaaga attttttcat
    12121 caagaagcag cgaatctgca agtggtttat tcaaaagaag atcatacggt ttatttcgat
    12181 gaagaaaacg ggtatgaatt ggaatggctc gtggctgatt cgaatgaaaa agaaatggag
    12241 cctgtcttgc tgacttttga aggtgcagga gaatataaga cgtttgaacc ttcattatct
    12301 gaaacgttta tttttgtatt agaaggggaa ttagagttaa gcttaggaga gacggtctat
    12361 gtggcaaaag caggacagtc gatctattat caagcgacaa aacaacatca attaaggaat
    12421 catctcaaaa aacgaacaaa agtattgatt gttgcaacgc aatcatattt gtaatatagg
    12481 gggtaaaaac gtggggaaac caatcatttc atttgatcaa gtagtgaaac gctatgatga
    12541 tgaaacagta ttaaaaaaag taagttttga gatcgaacaa ggaaaatttt atacactgct
    12601 tggtccttcc ggctgtggta aaacaacgat cctacgtatt atagctggat tcaccgaagc
    12661 tacagaaggg gacatctatt ttgaagggaa acggttgaat gatttgccag ctaataagcg
    12721 acaagtaaat acagtcttcc aagattatgc actttttcct catatgaatg tttttgataa
    12781 cgttgctttt ggattgaaga tcaagaaaat gtccaaatca gatatcgaaa agaaggtaaa
    12841 agatgctttg cgtatggtcc agcttcctgg atacgaaaaa cgggagatta gtgaaatgtc
    12901 tggtggtcaa agacagcgtg tagcgattgc acgagcaatt gtaaatgaac cgaaagtatt
    12961 gctattagat gaaccgttat cggcgcttga tttgaaacta cgtacagata tgcagtatga
    13021 actgcgggat ctgcaacaac gattaggaat cacgtttatt tttgttactc atgaccaaga
    13081 agaagcgttg gcaatgagtg atgagatttt tgtcatgaat aaagggaaaa tcgtccaaag
    13141 tggtacaccc gtagatattt atgatgagcc aatcaatcat ttcgttgctg attttgttgg
    13201 ggagagcaat atcgtggacg gtgtaatgat cgaagataat ctagttgagt ttgttggtaa
    13261 gcaatttgaa tgtgtcgatg gcgggatgcg tctaaatgaa ccagttgaag ttgttttacg
    13321 cccagaggat ttgacgatca cgacaccaga taaaggaaaa ctagtcgtaa cggtcgatac
    13381 tcagctgttt cgtggtgtcc attatgaaat catctgttat gatgaacagc aaaatgaatg
    13441 gatggtccat tcaacgaaaa aagctaaaga aggaagcaaa gtaggattgg cctttgagcc
    13501 agaagatatc catgtcatgc gtttcaacga gtctgaagaa gaattcgatg cacgtcttga
    13561 cagctacgaa gaataggggg gacaagaatg aaaacaatgc gcaggatcta ttccgtccct
    13621 tatattttgt ggctcggttt attcgtgatc gcgcctgtat taatgatcat ttatcaatct
    13681 ttttttgata tgaatgggca attcacgctg aataattatc tatcttattt tacgtcgggg
    13741 acatcgcttt ctatgacgat caattctgta tggtatgcat ttttgatcac gtttttcacg
    13801 ctgatcatca gttacccgac tgcttatttt ttaacaaaac tgaagcacaa gcaattatgg
    13861 ctgatgctga ttattttgcc tacatgggtg aatctgctgc ttaaagctta cgcatttatt
    13921 gggattttca gtgtgcacgg cagcgtgaat catttctttg attttatcgg gatcgggccg
    13981 aaacagatat tattcacaga cttcagtttt ctgttcgtgg caacgtatat cgagattcca
    14041 tttatgatta tgccaatttt caatgcattg gaagagatga atccttcttt gatcagtgct
    14101 agtagagatt taggcgcgaa tagctttgag accttccgac gagtgatttt tccgttatca
    14161 ttaaatggtg tgaaaagtgg tgtccaagca gtatttattc cttctctttc tttattcatg
    14221 ctgactcgtc tgattggcgg aaatcgggtg atcactttag gaacggctat cgaacagcat
    14281 ttcttggtta cacaaaactg ggggatgggt tctacaatcg gtgtgatttt aatcattgct
    14341 atgttcatcg tgatgctcct gacaggcgag aagaaaaaag gaggtcgctc ataaatgaaa
    14401 aaatttaaat ggtcgtatct ttatttaggg atcgtctttt tattcttata tgcaccgatc
    14461 ttctatctga ttttttattc cttcaatgaa ggaggaacga tgaacagctt tacaggattt
    14521 acttgggaaa attatgaagc tgtttttgaa gatacacgtt tgatcattat cgtattgaat
    14581 acgttcatgc tggctttctt atctgcattg atcgccacga tcatcgggac atttggggct
    14641 atgggaatct attacacgaa aaaacgacgt gcacggacag cgttgttgag catgaataac
    14701 atcttattag tctctcctga tgttattatc ggtgctagtt tcttgatttt ctttacacta
    14761 ctaggattcg gattaggttt tcagagtgta ttgctttccc atattgcttt cagcattcca
    14821 atcgtcgtct tgatggtctt gccaaaattg caggaaatga acgattcaat ggtcgatgcg
    14881 gctagagacc ttggtgctaa taatttccaa gtagtcaaaa atatcatttt gccttatctt
    14941 tctccaggaa tcatagctgg atattttatg gcatttacct attctcttga tgattttgcg
    15001 gttacatttt tcgtcacagg aaatggcttt acgacgctct cagtagagat ctattctcgt
    15061 gcaagacaag gaatcagttt agaaatcaat gcgctaagtg cgttagtttt cttgttctcc
    15121 atgatattgg tcattggata ctactttatt agtaaagaaa accgtccaaa acggctgaag
    15181 aaaaacagaa gagtacgcga gggggtggca cggctgcgat gaaaaaatta caatctctgt
    15241 ttttaggtat tctcatcatt attgcggtgc tgctgcttgg tgttcgtcaa cttgaaaaaa
    15301 caagtggcat gagtggagca aaggtactta ccatctataa ctggggagat tatatcgatc
    15361 ctagtttgat cacgaaattt gaaaaagaat atggatacaa agtgaattat gaaacatttg
    15421 attctaatga agcgatgttc acaaaaatcc agcaaggtgg gacaaactac gacatcgcta
    15481 taccaagtga atatatgatc caaaaaatga tcaaagaaaa actagtactt ccattagatc
    15541 attcgaagat caaaggatta aataatattg atccacgatt tttagacttg gattttgatc
    15601 cagataatca gtattcgatt ccatattttt ggggaacttt agggatcgta tataacgata
    15661 aattctttga tgcaaatcaa attaagcatt gggatgattt gtggaagccg gaattaaaag
    15721 acagtttgat gctgattgac ggtgcacgag aagttatggg gctttctttg aatagtttag
    15781 gctattcttt gaatagtaag aatatggcac agctgacaga agcagcaaat aaattgaatc
    15841 atttaacacc aaatgtcaaa gcaatcgtgg cagatgagat caaaatgtat atgatcaatg
    15901 aagaagcctc cgtggcagtg acattttctg gcgaagctgc cgatatgatg tgggaaaatg
    15961 aacatttaca ttatgtgatc ccaccagaag gatccaatct ttggtttgat aatatcgtta
    16021 tgccaaaaac cgtgaaaaat aaagaaggtg cctatgattt catcaacttt atgctagaac
    16081 cggaaaatgc ggcacaaaat gcagagtata ttggttattc tacaccaaat gaagaagcaa
    16141 aagcgttatt gccaaaagac atttcgtcgg acgaacaatt ctatccatct gatgacacga
    16201 tctcccatct tgaagtctac aaagatctag gatcgaaata cctaggcatc tataatgacc
    16261 tattcttaga attcaagatg tataggagat aatggcaaaa ctcagtaaga atggggactt
    16321 atcaacgttc taaagagcta aaaatcgtcc tttttctatc tgagttttcc aatcttctac
    16381 caaaagcgga tgaaacgccg ctttttttgt gttattttat tttttctacc acgtttttct
    16441 accagagaaa agtggacaaa accattgtaa aatagggccc gagacgggct agtaaatcta
    16501 agattgaaaa agttacagaa ggataaagta attggaaact atgcaaatat acttaaccct
    16561 tctgtaatct attaataaaa ctaatatatg aatccagttc aatatttgta gctatgaaaa
    16621 aacataaaaa tcatattaga taaaaactaa attggtagat aaattatttt gtcagatatc
    16681 tgaggcaaat attcgactat ttgtgtttca aagtaaaaat tggaatacaa atatagaata
    16741 gacatattgc agccgatagt ttattatgct tttagacaca ttaaactgga ggaaaaaatg
    16801 aaaaagagcg ctaaagatcg agtttttgat gagctgatac gactaacagg gaatatgtct
    16861 tctgtcactg ccgagaaaat ttcgaagaat ctaggtatct ctcgtcagaa tgccagccat
    16921 tatttgacga gattagtgga agataaaaag gtcgagaaat taccgggaaa gcctgttttg
    16981 tggaagcctt tagatgaata tgcggttgta gataatacgg agcaaataaa cgaagccttt
    17041 cattctgtag ttggtcatga cggaagtctg agagaggtca ttcaaaaatg tatagccgct
    17101 gtcaaatatc cgcctaacgg actcagtgta ttaataaatg gagccacggg tgttggaaaa
    17161 agttttttag ccacaaaaat ttttgaatac gctatccatg agcaaattat tgaaaaagat
    17221 gcaccatttg ctatcttaaa ctgtgccgat tatgcggaca atcccgaact gctttcggca
    17281 acactgtttg gatacaagaa gggggccttt acgggggctg aaaaggatac cgatggttta
    17341 ttggcaacgg ccaacaacgg ctatcttttt ctcgatgagg tccatcgcct atcgaaagaa
    17401 aatcaagaaa agctctttct atttattgat actggaaact atcgtccagt cggtgaaaat
    17461 gtaaattggc attctgctaa ggttcgtttt attttcgcca cgacggaaaa aggtgaaaat
    17521 tatttattag acacctttga tcggcgtatt caaattagtg ttatgttgcc aacttttgaa
    17581 gatcgcccca ttcgagaacg attagagctg attcaattat tttttcaaaa tgaagcggat
    17641 gttttacaaa aagatattat tgtttcaaga gaagccttgt ctttaatgtt atctcatccc
    17701 tttagtggga atattggtaa gctgaagaat atcattaaaa tcagttgtgc ggatgtgtat
    17761 agtcgaacac aagaagaacc attaacgatt gggaaaaatg agatcttgat tcagttaaat
    17821 atgctggaat ccgaagtaga aagcttgccg attgctagtt tattgataaa gaaaaatcaa
    17881 aagataaaaa cggatcgaat caaaccgttt gattatgatt cgattttgga aaaaattact
    17941 cagctgataa atgaaggtaa tttcaatgaa aatttttctt cgataaagaa tgaagtacag
    18001 catttggtgc atcacattga taaggattct tttttatcaa tgagtagaaa attgatgatt
    18061 cagatgttta gaaaggtctg ggtatccgtt ttaggaaaaa cgtacggatt gacgacgagt
    18121 ggacctgttg cagaaattat tagcagatcc tatgtcattt ccccaagcta taagacagac
    18181 ttaaccggga taaatcgtac attagctgca aatctacctc ggacgactta cttatgtaat
    18241 cagttcttgg agcatttacc accgctctca gaaaaggacg agaactttct aagactgctt
    18301 attgtcgtga ctttatctga ttatgtagat gaatccatcg agctgaaggg cctgttgctt
    18361 gctcacggag atagtacggc tagcagcatt caagcagtag tgaatcaatt atgcggcaat
    18421 tatgtttttg aagcgttgga tatgccagta gagagtaatg tgtcagagat tgtcgaatcg
    18481 acaaggaatt tcgtgaaacg gcaagtgaat acagatagtc tagtgctgat cgtagatatg
    18541 ggctctttaa atcaaattta cacacagatc aagaacgatt taaaagggga gttacttctt
    18601 ctgaataatt tgacgacttc cattgcactt gatattggct tgaagatgac gatgaatgcg
    18661 ccatttaaac agattgcgga ggatgcagca gacaagtatt caatcaatgt tcaatacttt
    18721 gaaggctttt ctcaaagtag caacattatc atttcctgta tgtcgggttt ggggatttcg
    18781 gacaaattga aagatgtttt tcgtcatcat ttatcggatg aatccatcga agttttcacg
    18841 aaggactaca gagaactacg tgaattaatc gaccaaaatg atgaaactta ttttgacaag
    18901 acaaaattgg tcatcacgac ttcggatctt ccacgttcct tttcaattcc taatattaat
    18961 gtttatgaca tcttagacgg tgatggagca gccaatttgg agcatatttt gagtcctgaa
    19021 atgaagccgg cagaatttaa ccgcttgatt caggagctag taaaattctt ttcgttggaa
    19081 ggaattgcgg accgtttgaa ctttctgaac ccaacgatcg tgatgagtga agtggaaaca
    19141 gtcatttcta aatatgaaaa ttactatcat ttcactttaa atggccgtgt aaaactaaat
    19201 ctctatatgc atacggcatt gatgatggaa cgtttattct tggctcggac agaaaaatct
    19261 gaagaaccga attatgattt gaaaccagat gaagatgaat tttattatgt ttctagaagt
    19321 atttttcaat caatggagat gaaatataat tttaaagtca atgcttatga gctttcgctg
    19381 ctctatgaat tattaggacc gtatattcaa aaataaagtg tctaaaaaag tgtctaatct
    19441 gtttttttta ggttagacac tttttttaat gtgaattaac gtgattaaac caatgttttt
    19501 aaaagttggc acaggaattg cttatataaa agtgaacaga aagaaaggaa ttaaccatat
    19561 gaagaaaatt ctaatagcga ctcacggtca cttagcttca ggctttctta gcagtattca
    19621 attactgacg gggaaggttc aagagattac ggtgattaat gcttatgtgg atgagtgtga
    19681 ttttgaacag gagttgaatg tatttgtaaa ccaggtgaac gagcaggatc agatttttgt
    19741 ttttaccgat ttatttggcg gaagtgtcaa tcagaagatt accaaaacct ttttggagaa
    19801 agagattgct gtaactattt tgtctggctt taatctgcca attctgctcg aaatagtatt
    19861 ggcaaccaag gaattaacaa aggaggatat tcaggaactg gtaaataaat gccaacagga
    19921 attaaagatg accattcttg atgaggtaca tgtagtaaat gaagaggaag atttttttta
    19981 ggaggaagaa aaatgattaa agcagtgcga attgatgaac gattaattca tggacaagta
    20041 gcgatgactt ggacaaagag tctaaattta accgggttag tagtagcaag cgatgaggcg
    20101 gctaccaacg atattcaaaa gatgacattg aagatggctg caccatcgaa tgtcaaagtc
    20161 attattaaaa cagttgatga cgcgattcat ttgttaaaag atccgcgggc gaaggacatg
    20221 cgcttgatgg ttttagtccc taatgtcaaa gatgcggtaa aagttgcgaa agctttccca
    20281 acggaaatcg aattaatgaa cgtggggaat gctgggaaaa tgacaccgcc atcggaagat
    20341 aagaaaacct tatcaaagga agtgatgtta acgacgtcag aaattcaaga cttaaaagaa
    20401 ttagttgaac tttatccaga taccgttttt cagcctacac cggcgatgga aaaacgttca
    20461 gctatctcta ttttgagtga tttttagaaa aaggaaggag aaaaattatg tatgatgcat
    20521 ttgtagtcgc tttggccgtt tttattggag ttgctggaca tgaaatgttc gggatgtcca
    20581 tgctgagtcg tccgattgtt gttgctccgt tagcaggagc gttgatgggg gatttgcaga
    20641 cggggttgat tgtcggggcg tcactagaag ccatctttat gggtgtcgtc aatatcggaa
    20701 tctctagtac ggcggagcct tctttggctg ctgggctggc tacagcgttc gcaatcaaaa
    20761 tgggaggaaa cgtggatgcg attattccca ttgtctttcc actagcagta ttaggattac
    20821 agttaatgaa tatgattttt tcttttgtat gtggaccgat ggctgctaaa tttttcaaat
    20881 ttgcaaaatc tggtgatcaa aaaggaatca tcaatctgca cttctttatg tggtttgtcc
    20941 actatgcgct ttatgctctt attccattct ttgccgtttt atttggagca gatgttgtca
    21001 aaagcgtctt ggataatatt ccagaggtca tcatgaacgg attaacagtc gctggaaatc
    21061 tgctgccggc agttgggatg gcgatgctgt tacggatgct ttggagtaaa aatattgctg
    21121 tgtggttttt ctttggggcc gttgttatgg cgtatctcga gttaccattg attgcaattg
    21181 ccgcagttgg aacgattatt gcaattgtta tagcccaaag agatctacaa ctaaaaaata
    21241 tatctgttca tgcagttcaa agcgatgctg ctgtaaatgc aacgcttgac caagaagagg
    21301 aggatttctt tcaatgaaat tagctgatgg aatttctaaa gatgagaaaa aattggttcg
    21361 gaagatgttt tggcgctcga tgactatgta tgcttcggtg aatccggtga cgatgggcgg
    21421 cggtggtttc gcctattcta tgatgccctt cattaatcat ttctacaaaa gtgaagaaga
    21481 tcgagctgcg gcgctggaac gtcatacaca gtatttttcg acgaccattc cttgcgcgtc
    21541 ctttgtcatg gggattgcgg catcgatgga gaaggaaaat tctgaaaaag ctggttttga
    21601 cgtggaaagt atcaacgcga tcaaaacgag tttgatggga ccattggctg gaattggcga
    21661 ttcattgttc tggggagttt ggcgtgtcgt taccgcggga ctagcgatca acttagccaa
    21721 tgccggaaat attttggcac caattatctt tttagttatg ttcaatatac ctaattactt
    21781 gatgcgatac tatggcggcg ttttaggcta ttcattaggc tctaaatata ttgaaaagct
    21841 gtatgcgaac gggttaattg aaattctgac aaaagctgct agtatcttgg gtctgatcat
    21901 ggtaggtgca atgacgatca gtatggtcaa attcaatacc gttttgagct tttcaatgaa
    21961 gggcgaagaa ctaatgaatg tccaagaaat cctcgatagt atttttaaag gaattgtacc
    22021 gttattggta acattgagct gtttcaaatt actagataaa aaagtcggcg tcatcaaaat
    22081 tatttttgga atggtcgtct tgggaatttt attgtcatta cttggaatcg catagtagga
    22141 agctgcagct actaggctgc agttttttta gcaaggaggg aaaagatgac tattaatgaa
    22201 gtaatttatt cacccaaaca cccatttttt aatgctgagt taaacgacgg aaatgtgact
    22261 acttcaaacg aatacagcta ctatcggaat attcctgatg taaagggatt gaccttcgat
    22321 gtaagtaatc aaaagacatt agcaaacctt gatgtttgcg ggacgattca aacgttgacc
    22381 ttttatcgag aaaatttact aactgaggaa aaaccaggtg tttgggtcaa taaacagctc
    22441 tctcaaacca attcgttatc cttaaaggtt gaagtaaacg ggattgtcta ccatttgtca
    22501 gaatcggatc atcgtattga agtcgatgtg attcaagact gtttgcctag atatattcat
    22561 cattattcga cgtttaaggt cattgtagta tcctttgctc ccatactggc taataagcgt
    22621 ttaagtatgc ttgttcaaca ggtttacatt gtgaatgaaa cacacgaaag ccttcaagtt
    22681 tcagtgaaag atgtgccttc gtatcaagag aagtattcgg atcagcaaaa tgtgttgatt
    22741 tctcaaaaag gaaataagga cacgatcgca caacaggaag tggcaagctt cgccattgct
    22801 tttgtggacc caaatgcttt tgaagaagta atgacttttc aggaatctga tatcgaaaaa
    22861 tggctgaagg aaacattgaa ctattttgct cagctatttg ggcagctgtc aatgccaaac
    22921 gatagagttg tccatctcta tcgtcgtgca ctttatcaaa gcttttctag tttcggtatg
    22981 aatcgacagg gacaggtcgt cggcagcaat tggggcagct atcctgctac taatcgaatt
    23041 tggaataagg atatgtatta cgcatcattg ccattcacca tgtttgaacc ggagttatgt
    23101 caaaaaacgg ttctatggtt tgatcaatat ggcgttaagt ttcctggttc aaaatttaca
    23161 ggaggtatca atcattctct gagtaattcg ttatccagtg cgttactggc tagtctttat
    23221 tttgaacata ctggggatac aaaattcttt gagcggtgtc cgcaggttct actgaatgct
    23281 tcaagaatta ttgaggacat attagctcaa cgtcggtcag gggaaccaat gctttttcca
    23341 tctgtttggt tatcagacgc ctttgcactt ggaaagtatc ataccggcag caatctttgt
    23401 ctttggaagg cctgtattgg acttgcagaa atttttgaag ccctagaaca actgagtctt
    23461 agcaagcgat acaaaaacat tgcctgtaaa ctaaaggaat caatttgtaa acaaatgact
    23521 atcgatggtc cttttggtga gcaatttttg gagggaatcg gtgatgagga gaaaacaacc
    23581 tattcagtga agcactatca aaaaccgatt cttgagcaag ggttaatctt tttaagtgat
    23641 gtgattgtgg atggaaaaat taatttattg atgcatgatg gagaagaatc agacactacg
    23701 ttgatgcctt tttatcaatt tttagataat aaagatcatt tatatcagaa caccatggcc
    23761 ttttctgcta gttctttcaa tccaacctat agcgaggaaa tcaaaggcat cacttgggga
    23821 ttagaatccg gcgccacttt tcctggcttt atcactgttt taatgagcga gctgcacaac
    23881 cctcaagctt tcgtaacccg attagaagaa ctaatttgtt tggcagattt agacggttcg
    23941 tggtggtggt ggccgtatcg cttagaggct caacaaggag aagtcgtgcg agactttggc
    24001 tgcggcaaat gcggctgggc atcgggtctt tttgtcagcc taatgatcag tcaatatttc
    24061 ggattgaaat tcaaaaaagg agtattgcaa attgatcctg ttgataattt aacgttttct
    24121 tggaagaatt tgaagttcgg tcaagccttc atttcgattg aatgtacgca atccgagttg
    24181 agtatttcaa atttgtcaga aaagccattg aaaataagtg atacgaaaaa aattcttcac
    24241 gtagaaaagg gaaaaacgat tcacattcaa aggagaaaaa gatgagtata ctaaaaaata
    24301 ttacccaatt taaaaaaatc cagagtcgag caatcactcc cgaaaatcca acaggcgaga
    24361 aaggtaaagc tgcgatgttg ccaagcgagc taggaccaag ccgcaaaggt cgtggcgcaa
    24421 ttccgctgac ttctggtgaa gaaactgtga ttgcggatat tactggaacg ggaataattc
    24481 gtcatatgtg gatgacgatt cgtgatcgaa cagaatttgg cagttttgtt ttacgtgatt
    24541 taatcttaag aatttattgg gatgggtcgg atagccctgc tgttgaaagt cctttagggg
    24601 atttcttttg taatgggttt ggagagcgtt gcgaggtgaa ctcgttgccg atagtggtta
    24661 atcctacagg gggctttaat tcctatttcg aaatgccttt ccaaacatcc gctaaaatta
    24721 cgatcgagaa tttacatccg aaggatatgt cctcattttt ttatacgata aattacgctt
    24781 tggtggacga attggaagaa aatagcctat attttcacgc aaattggcat cgggaacgca
    24841 ttaccaaatt acaggaggat tataagttaa ttgatcgatt aaagggtcaa ggctattacg
    24901 tgggtactta ccttgcgctt acctgcctag aacgttattg gtggggcgaa ggcgagttta
    24961 aattctacat tgatggggat agtgagtatc cgaccgtaac ctcaacaggt tcagaagatt
    25021 attttggcgg ggcgtgggcc tttcatgagt acgatgagtt cggacgtcca catgcgaaaa
    25081 actattcaac agccttttta gggtatcctt accaatcaaa tagagatgcc acaagagatc
    25141 gttttgaaac gggaaaattg aatgccgttc atgcctttgg tgacgacgca atgccacgac
    25201 atggtcttta tcgttggcat cttcaagacc ccatctgttt taccgaagat ttatcggtca
    25261 ctttacaaca aatcggcaac gatgatgttc gcttatttga gcggcaagac gatgttgcta
    25321 gtgtcgctta ctggtattca acagaagctt caggaaatac taaacgtcat ttcactgatc
    25381 gagaacgctt gccgcgttaa tgaagtgttt ttcacatatt cgaagggagg aacctatgat
    25441 gatatatggg gcaattgaag ctggagggac taaatttgtc tgtgcagtcg gtactgagga
    25501 attaacgatt ttggaaagag tcagttttcc cacaacaact ccagttgaaa caatgaagca
    25561 ggtcattgat ttttttaaac cttttaagga acaattggca ggcatcgggg tcggctgctt
    25621 tggtccaatt gatattcaat gcaaatcaac gagtttcggt catatcacat caacaccaaa
    25681 acttgcttgg caaaatttca attttgtagg aacgctaaag caatatttca atattccgat
    25741 tgaatggaca acagatgtca atgcggcttg ctatggtgaa tatgttgctg gttctggcaa
    25801 agggttagca ggtgttgcat acttcactgt gggaacaggt atcggaggtg gtgccttgtt
    25861 caatgggact ttcgtggaag ggttcagtca tccggaaatg gggcatatgt tgatcaagcg
    25921 acatccaaag gacaattttt caggaaactg tcccttccac caagattgtt tagaggggat
    25981 ggcagcagga ccagcgattg aaaaacggtt gggtgtaaaa ggccagaatt tattggctga
    26041 cgattcgttt tggcagattg aagcctttta ccttgcccaa tgtgcataca atacaacact
    26101 gatgttttcg ccagatagaa ttatttttgg cggtggtgta atgaaacaag aacacatgaa
    26161 gaaaaaagtt caggataaat ttgttgagct tataaatgga tatgttgaaa taccaccaat
    26221 tgatagctac attattacgc ccgaattagg tgataatgcc ggaataatcg gcggattagc
    26281 attggccaga aaagcggtaa gaaataagca accataatta atgaatgttt cattgatact
    26341 catgtcaaaa gtatttaacc gagtaatcaa atgatcaaat gaagttggat aaagcgaaaa
    26401 tgaattcaaa taaaaaggct ctaagtcaaa tcgtgttgtt ttcattaaat cactgaaagg
    26461 aaatgcttct gcgtttcctt ttttcttttt gttgtgcgct gtataccttg aggatattca
    26521 ctggtggcgt acacttaaat agtaatatat tgtgttactt tatgtctgtg gtaatagtta
    26581 tagttgctta ccaatgtatg ttcatttttc gaaatgttga cttcataatc cttggcttaa
    26641 tgtttgaatt tttttggtga tagatttttt cagccgtata aaataaatcg taattctatt
    26701 atagagagtt gtgattataa aaagatagca agaaaaaaaa agaaagtttc tatacatttt
    26761 aaatatttta ttcctatttc tattgctaaa aaagtagaaa ttctatattt acctttaact
    26821 ctcgcttctc ttgcaaatgt agttagcatt ttaatcgata ataaactcag gtagttatat
    26881 taccttgaaa tgattgataa ttttgtcact tctatttttt ttgcaataaa ttttttattt
    26941 tagtgaaaaa taagaaacta tttctttgaa ggcgataagt tagaaaaata ttattgtagt
    27001 cttttcttta ttaggaatca tcactgttgt atcttattac cttttctgtt tttcttatta
    27061 gagaaaaata atttgagagg tagatagttt ttattggagg aagtaattat gtatattttt
    27121 gaaacaaaaa tttttcattg caataattgc aacaaagaaa tttcatcggg ggaagaggtt
    27181 tggacaaaaa tggaaatttc cgccaaaagt aactgctcct caactgaaat caattaaaga
    27241 actagaattt gagaatgcac tggtaatttg tatgacatgt actgatgaag tatttcgaaa
    27301 acatttttaa aggttgagat gtatatagat ttaaccaatc atttatctct ctcggaaaag
    27361 gaatattaac taaccagcgg gttatcaaaa ataggtagga aaactgtact taatggctta
    27421 tttcgcgctg attatgagaa tatcagtctg tttgattaat ttttagggtt caaaatacag
    27481 agacaaactc caggtcgggt ttcgccacaa gcgaa
//
LOCUS       DAKCAA010000034        27101 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000034 DAKCAA010000000
VERSION     DAKCAA010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.034"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(57..509)
                     /locus_tag="OUE31_001600"
     CDS             complement(57..509)
                     /locus_tag="OUE31_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222613.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(974..1342)
                     /locus_tag="OUE31_001601"
     CDS             complement(974..1342)
                     /locus_tag="OUE31_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HCU0222614.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            1492..1974
                     /locus_tag="OUE31_001602"
     CDS             1492..1974
                     /locus_tag="OUE31_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HCU0222615.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            2011..3021
                     /locus_tag="OUE31_001603"
     CDS             2011..3021
                     /locus_tag="OUE31_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HCU0222616.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(3136..3849)
                     /locus_tag="OUE31_001604"
     CDS             complement(3136..3849)
                     /locus_tag="OUE31_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222617.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(4039..4629)
                     /locus_tag="OUE31_001605"
     CDS             complement(4039..4629)
                     /locus_tag="OUE31_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HCU0222618.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            5113..5340
                     /locus_tag="OUE31_001606"
     CDS             5113..5340
                     /locus_tag="OUE31_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HCU0222619.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            5356..6522
                     /locus_tag="OUE31_001607"
     CDS             5356..6522
                     /locus_tag="OUE31_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HCU0222620.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            6756..7799
                     /gene="hrcA"
                     /locus_tag="OUE31_001608"
     CDS             6756..7799
                     /gene="hrcA"
                     /locus_tag="OUE31_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HCU0222621.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            7893..8456
                     /gene="grpE"
                     /locus_tag="OUE31_001609"
     CDS             7893..8456
                     /gene="grpE"
                     /locus_tag="OUE31_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HCU0222622.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            8507..10336
                     /gene="dnaK"
                     /locus_tag="OUE31_001610"
     CDS             8507..10336
                     /gene="dnaK"
                     /locus_tag="OUE31_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HCU0222623.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            10487..11653
                     /gene="dnaJ"
                     /locus_tag="OUE31_001611"
     CDS             10487..11653
                     /gene="dnaJ"
                     /locus_tag="OUE31_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HCU0222624.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(11735..12400)
                     /locus_tag="OUE31_001612"
     CDS             complement(11735..12400)
                     /locus_tag="OUE31_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222625.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            12376..12549
                     /locus_tag="OUE31_001613"
     CDS             12376..12549
                     /locus_tag="OUE31_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222626.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(12594..13331)
                     /locus_tag="OUE31_001614"
     CDS             complement(12594..13331)
                     /locus_tag="OUE31_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCU0222627.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(13333..14835)
                     /locus_tag="OUE31_001615"
     CDS             complement(13333..14835)
                     /locus_tag="OUE31_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HCU0222628.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            15094..17088
                     /gene="uvrB"
                     /locus_tag="OUE31_001616"
     CDS             15094..17088
                     /gene="uvrB"
                     /locus_tag="OUE31_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HCU0222629.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            17098..19914
                     /gene="uvrA"
                     /locus_tag="OUE31_001617"
     CDS             17098..19914
                     /gene="uvrA"
                     /locus_tag="OUE31_001617"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCU0222630.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            20177..21442
                     /locus_tag="OUE31_001618"
     CDS             20177..21442
                     /locus_tag="OUE31_001618"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HCU0222631.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            21446..22177
                     /locus_tag="OUE31_001619"
     CDS             21446..22177
                     /locus_tag="OUE31_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HCU0222632.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            22312..23196
                     /gene="rapZ"
                     /locus_tag="OUE31_001620"
     CDS             22312..23196
                     /gene="rapZ"
                     /locus_tag="OUE31_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HCU0222633.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            23193..24191
                     /locus_tag="OUE31_001621"
     CDS             23193..24191
                     /locus_tag="OUE31_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HCU0222634.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            24225..25160
                     /gene="whiA"
                     /locus_tag="OUE31_001622"
     CDS             24225..25160
                     /gene="whiA"
                     /locus_tag="OUE31_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HCU0222635.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            25703..26353
                     /locus_tag="OUE31_001623"
     CDS             25703..26353
                     /locus_tag="OUE31_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222636.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            26540..>27101
                     /locus_tag="OUE31_001624"
     CDS             26540..>27101
                     /locus_tag="OUE31_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HCU0222637.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         8933 a         4569 c         5722 g         7877 t
ORIGIN      
        1 aaaaaatagc gctagaattt ccaacatctc tggaatttct agcgcttttt aattgtttaa
       61 gatacaaggg aaatatctgt ctggatcaat aatttttcat tgatccattg actaaagttt
      121 acgacataat tgaagttacc accgattagt atctccgcat gattgtcttt ataaagatcg
      181 tattgtaaaa gacggtcttt tttatttgcg taaacatcgt tatggtactg gactaattgt
      241 tctcggaatt gattgattgc tgtaaaatca cgatattgaa ggttgaaacg catcgtgatt
      301 ggtgcattta gcatgaatcg ctgcatttct tttgctgctt cctctgcttg atctccgtat
      361 aggaactcaa aaagattacg ttcagaaaat ttccattgcc cgccaacctt tgttcctttt
      421 agttttcctt catgaagata atttctgata gaacgtgtag taacacctaa ttgttcggct
      481 aattcattta ctgagtaaaa atctttcaat gttcaccctc ctatgtgaat ggttctactg
      541 acttagttga tatttgctta atcacgaaat gtagaaagaa cgattttaat taaggtcatt
      601 gtaaaaatca agtcagaaaa ttctaacttt tatttctcta aagaaattcg ttctctccta
      661 aagtgatatt atatttaaat atacctgaaa ataatgggca gtattatgaa agatcactga
      721 tattttctcg tattttttcc ttattcaaaa gttttgcagg aaaattgctg aaaaaataat
      781 tttactaagt agaaaattca aagccattca atcagtgatt tttttcagca caagaaagac
      841 tccttataaa aatagcagat actttgtcaa ttaagtgttt aaccagggat gataaaaagg
      901 ataggattga acaaaacctg tataaggtga tgaatagttt cctcgccagt aaaaggttta
      961 ttcgtataaa gctttatcgc caaaatttat catgaccttt tttatcttca atattaaatg
     1021 aaatcaattg ttcaatcaat tcccagttga ttacactttt ccaaggaact ttgatgacgt
     1081 tatccgtata tacgtagcct gcttcttgga tatttttttc aagggcacga atcgctgctt
     1141 tttccggtgc gatagaaaaa tgatttttag caaaactaaa tgcaataata aaggtaccat
     1201 ggtcagtaaa cataggttgg ttccatttta cagttgtgtc tagctgggga tacgtttctg
     1261 ttatcttagc aaaaaggtct ttgatctttt gttgatgttc tttttctttg atttgattga
     1321 tgatcggctg aaatttttcc attctaaaac gcctccatta agtggtttga tttattttac
     1381 cagaaaaaca atagttatgt ataaaaaacg aacaaaacac aagtaatgtt gtaaccgcta
     1441 tatttatatg ataagatgtc tcaaataata aaatagaaaa gagacataaa aatgattgac
     1501 ttggcaaaga aattcttaca cgaaaatata tattttgagt tgtatcatca tcgagccatt
     1561 tatacaaatg aagatgcttt ggtaataaag aaagaacaag gatttacagg tacagagacc
     1621 aaaagcttat tcttaaaaga taaaaaagat aataactacg tatatctgac ttttactacg
     1681 aaacaaacgg atttcaaagc attagggaag atcgtcggta aaaggctttc tattgtttca
     1741 tcagaacgca tggaagaaca aacgggacaa aagcagggcg ctgtttctcc gtttggttat
     1801 gaaaaacaga ttccgattat tattgatgaa gagctcttat caaatgaaaa acttgttttt
     1861 gcaccaggta gaccagatca aacgatggtc atccaaacgg ttgacttaaa caaaatcatc
     1921 cagctacttg agatgccgat atttttgatg ccggcaaacg aaaaaaacaa ttaaccaagt
     1981 aaaatagtgc atacttggag gtgaagcaac atgataagtt atccattatt agaaagaaat
     2041 gcaacgattg gggttactgc accatcctca ggcgtatcag aggaacacca ttcgttactc
     2101 gaatcagctt taaagagaat ggaagaaaaa tctttccaag tagttactgg aaagacgctt
     2161 tggacgcaag ataaggaaaa atcaggtcca gcaagaaaac gagcagatga attcaatcaa
     2221 atgatgcaag atgaaaatat ccaaatgatc tttccgactt ggggaggaga attattgatt
     2281 gagattctcg attttgtcga ttttgatgct ctacaaccaa aatggatagt aggttattca
     2341 gatattagta cgttgctact tgctgtcaca ttaaaaacag ggatagccac tgcacatgga
     2401 actaacctta ttgatttaag aggagagtac ttggatgaaa cgacagcaat gtgggaaagt
     2461 gtactgaaaa caagagaagg agaatcgatt ctacagcaat cttctgaaaa gtatcaaaaa
     2521 gtgtggcccc atgagcattc atcatcttct gttttccatc tcactgaacc aacaaattgg
     2581 caatcagtca gcggagatgc agtaaggatg aagggacgat tattaggtgg ttgtattgat
     2641 acgatcaggc atttaatcgg tactccttat ggagatgtcc aatcttttaa aagaaagtat
     2701 aatgatggaa agccgatctt gtggtttcta gaaaactgtg agctatcgtc agttgattta
     2761 agaagatcac ttgttcagat gaaactggca ggctggtttg atggcagctc ggggatcatg
     2821 ttcggtagaa gtgcggcaga ggatttgtta gattataaaa tgaaggatgt atacgaagat
     2881 ctgtcaaagg aattaaaact accgatcttg tatgatattg attgtggtca tgtaccgcca
     2941 caactgacat tgattaatgg tgcctatgca gaagtagcgg tagaagatag aaaagcgact
     3001 gttttgcaaa cgtttattta aaaaattttt tcctgccttg gagtctatca aagaccaata
     3061 aatctaaata gaaaagaaag tgaaagaagc tgacaaaatg ctgtcagctt ctttttgtat
     3121 aacatattag aaagtctaat tatctataac tgtcacatcg attaactgtt tcacgtcatt
     3181 gggatttcct gtaggaatag ctactacaga tgcattatca atgatttctt gagttgtttc
     3241 tctaatgaac gctggataag atgtttgatc tgcaggcatt tgccaatgtg aaggaactgg
     3301 ataactagtg attgtcccgt catggttact tgaatacact aaaactccct ggtaactgta
     3361 tttcccagtg agcataacca catctttcgg atagactgca ctccctgcat cataaggggc
     3421 gataggtgtt cctgcaggat aatgaataac atgtaattcg aaatcacccg atgtatctct
     3481 aaaagtatta cctctaatag ctagccaaac acgtgcgtac tcaatttgta gatcagaata
     3541 tcctgctaac ggatctattg actgagaaga ctgtgaggag gttgtgtcta ttgttgaaga
     3601 agaaatattt gtctcaactg tactactaga tgtagaagaa gtattgggct ctgagacttt
     3661 actgcttgtt gaagatgtat tcgtttcagt agaagctgat ttctgagtac ttgatttttc
     3721 agctgaactg gtttgtctga ttgaactttt gtctgtggtc gcagatggat cactattttc
     3781 tttactagga gacgtacatc ctacaaggaa taaagagacc aacaataaaa taaaacctaa
     3841 ctttttcata taaaatacct cattattttt ttaataccag tatagcataa tcctgaattt
     3901 ttgaatccgt aaaaccttgt ctatgaatat aaatagagtg tatcttcttt gataaatgtc
     3961 agaaaaagtg tgacaaataa tcatcagtaa aattacttgt cacactattg ataaggagta
     4021 tttaattgaa gagaatgatt aggagaaagg atctccgtac tttttatagt aatcatagaa
     4081 tccaagtttg tatagacgaa tcgttttttc tcttatttct tctgtttcaa aatggactgc
     4141 ttgaagaatc aagtctgtga attctatagg agctgttcca ttcgcagtaa tcaaattacg
     4201 atctttcaca gcttgttgtt ctataaaatc ttctttattc tgataatttt ccgattctaa
     4261 ccaaggaaat tgcgcatttc cggtgtgttt gtaaccttgc aataatccgc tctgagctaa
     4321 ataatcaact gccccacaaa tagcagctac tggtacgtct gtttttaaca atttatcgat
     4381 tatttgatat aaatgatgat tttttatgtc ccatgaattg ccaccgatca taataaaaag
     4441 gtcaactttt tcaggtattt gttcgattaa gtaatcgatt tttgttttta atcctccaat
     4501 ggaagtgacc tctgattgga tagaagcagt tttgttttgc catttctcat tttggtttag
     4561 tgtgctagta atataagcac cttcccaatc ggcatattcc tctaatagaa acgtaatcgc
     4621 agttttcatt ttcaagctct cctttactat ctataacaag gacaacagtt ttaacctaca
     4681 gacattcatt aaaattgggt agcgacagcg aaaacaacaa ttcttaagtt ttagacagag
     4741 tatacagata gtcaacttaa ttaaatacga actaaataaa aatgacaggt aatcattttt
     4801 gtttaccagc attataacat tttgcataca tggatgacaa aagaaccaat tcccacttgc
     4861 ttgagtacaa tattaaaaga aactggaagg caaaaagtaa ttatagaaac gaaaaataaa
     4921 tcatatcggg cactcagaca tgaaaacaac cctagagata tataactagg taaccagttt
     4981 aatgaaagaa aaaatcatcc aagaagtcga ttcttggatt ttttagtgga tttgttcgcc
     5041 aaatacgttt agtatgcgta tatgagaggt tgtaagcaaa gcgttgtggt ctgagcactt
     5101 aaggaggaat ctgtgaaaat agcttttcat atttttgcag attttgactt aatgccgaag
     5161 gtcagctttg cgattaccgt ttatcgagag gctgtaaaag caccgtgtag ctccgatgac
     5221 aataagcaag catttttaga gctaggtttc cttgattcta aatatgcggc ttatttcaat
     5281 gagttggtgc ttgaacgcga ttttaagaag gtcgaaaaca ggcacgactt ttcgacgtaa
     5341 ggagaaagaa tttcaatgat agaaacaata aatcccgcag aaaacaaggt ttctgcgtac
     5401 attcatatcc cattttgcga gcatatctgc tattactgtg attttaataa agttttttta
     5461 gaagggcagc cagtagatga gtatgtggaa atgctgctga atgaaatgaa aataatgcta
     5521 gaaagtcatc cgacagcgaa tttagaaaca ctttacgtag ggggcgggac accaacttct
     5581 ttatctgcta aacaacttga tcgactgtta tcaggtgcta gagagatcct gccttttcaa
     5641 aatggtaatg agtttactgt agaagcgaat ccaggtgatt tgacccgtga aaaacttcaa
     5701 gtaatgaaaa actatggcgt caatcgttta tccatgggag tgcagacatt tgataatcgc
     5761 ttattgaaaa aaattggacg taaacacacc gcagaagatg tgtatcaaac tatgcaattt
     5821 ttagaagcag aaaattttac caatgtaagc atcgatttga tttatgcatt accgggacaa
     5881 acactagaag gatatctgga tactttggaa aaagctttgg ctttggatct gcctcactat
     5941 tctttgtact cattgatcct cgaaaacaaa acaatgttca tgaactgggt acgacaagga
     6001 agactcgaac tgcctgatca ggaaacggaa accagaatgt ttgaagagac gattgaagca
     6061 atggaaaagc atggacgtca ccaatatgaa ataagtaact ttgggctctc cggacatgaa
     6121 tctcaacata acctcatgta ctggaacaat gaccactatt ttgggtttgg agctggtgct
     6181 agcggttatc ttggagatat tcgttaccgc aacaaaggac caatccaaca ctatttacgc
     6241 ccattacgag caaatgaacg cccggtattg gaagaagaaa aattgacacg aaaaaatcaa
     6301 atagaagaag aaatgttctt aggactaaga aaaaaaacag ggattactaa aaaacatttc
     6361 tatgatcgct atcaaaaaac aattgaatcg gtgtacggtg atgtgctaag ggaattagag
     6421 caagaagggt tacttgttaa tgaagaagac cgtgtttatt tgacaccaag agggaccttt
     6481 ttggggaaca atgtgtttga gcgctttttg tttgaaaaat agtttaaaga atatttgttt
     6541 tttatctgaa tttaaataaa aaaagttcaa aaatacaata aaggactatt gaaacgttga
     6601 tataactgga tttacatcaa ttatttagaa ttagcactct tgtgtttaga gtgctaaaaa
     6661 atggagtctt tctcttgaca ggagaagggc ttcttgctat atttataagt ggattagcac
     6721 ttagaatata tgagtgctaa tgagaggtga ggaagatgtt aacaaagcga caaaacgaca
     6781 ttttacgtct gatcatccaa cactatacga gtagtggcgt gcccgttggt tccaaaacat
     6841 tgatgtctga gggagtcaag gccagctcag caacgattcg caatgatatg aaagcattag
     6901 aagatgaagg attgctgttg aagactcact cttcttctgg gcggattcca tctgctttag
     6961 gctatcgtta ttacgtggat catttgttaa aacctgctcg cgtagcagaa gatgatttgc
     7021 tgctgattcg tcagtctcta ggcagagaat ttcatgaaat caatgagatt attaagcaat
     7081 ctgctgagat attatctgag ctgacaagct atacgacttt ttcattggga cctgaaataa
     7141 aagaccgccg actgactggc tttcgtatcg tacccttgaa taatcgacag attattgcta
     7201 tcgtcgtaac agatatgggg aatgtagaaa gccaagtgtt cactcttccc gaatatatgg
     7261 gaagtcagga actagaaaaa atggtacaga ttgtaaacga ccgtctagtc ggagatcctc
     7321 tgatgacggt gtaccataaa cttcgtacgg agattccgat gattcttcat aaatatttcc
     7381 aaacgacaga agggatgtct cagttatttg acaccgttct tggtcatgtt tttgaagata
     7441 aggtttatgt cagtggacaa atgaatctct tggattatga gccccgtcaa gatcttgatc
     7501 agttcaaatc gatgttttct tttatgaaag actcagacgg acttacacaa atgatcactc
     7561 cgatggatag caatattcat atcaagattg gtgctgaatt aggcaatgat ttattgcaga
     7621 atatgagtat gattcaagca agttacgaga tagatggtca tggaagaggt acaatagcct
     7681 tgttagggcc tactagtatg ccttattctc ggatgttcgg tctagtcgat gtttatcgaa
     7741 gagaactagc agctaaactt gctgattact accgttcgct tgacttgtca aactcgtaat
     7801 gtgaataacg aagctatttg cagctgatcg ttctctcttt cttagtaaga gcaatcaaac
     7861 agctgactga ataatgaaag gaagactgta tcgtgaaaga aaatcaagaa gaactagata
     7921 aagaaatgac agatgctcag ccagaaccgg aaatcgatgt cgaagctgca gaagattcgg
     7981 gtatttcaga agctgaagcg gaagaattcg aaacagcgaa attaaaagct gagttagaag
     8041 aaatggaaga taaatacttg cgggctcgtg ctgaaatcgc aaatatggca aatcgaggaa
     8101 aaaatgagcg tgagcaatta caaaaatacc gttcacaaga tttagccaaa aaattacttc
     8161 catcaattga caacctggaa cgtgcattag ccacagaagt gtcagatgat caaggggcag
     8221 gtttgaaaaa aggcgtggaa atggtcttgg aaagtttgcg taacgcactg gaagaagaag
     8281 gaattgaaaa aatccctgct aaaggagaag cctttgatcc taatcttcat caagcagtac
     8341 aaactgttcc agcgactgaa gatacaccag ccgatacgat tgtagaagta ctacaagaag
     8401 gctacaaatt acatgatcgc gtgttaagac caaccatggt cattgttgca caataattgt
     8461 gcggatataa aacttacact ttcaattaaa gaaggagacg ttaattatga gtaaaattat
     8521 cggtattgac ttaggtacga ctaactctgc agtagcagta ttggaaggaa acgaagcaaa
     8581 aatcatcgct aacccagaag gaaaccgtac aacaccttct gttgtatcat tcaaaaatgg
     8641 agaaatccaa gtaggggaag ttgcaaaacg tcaagctgtg acaaacccaa atacgatttc
     8701 atcaatcaaa cgccatatcg gtgaagcagg ttacaaagta gatgtagaag gtaaatcata
     8761 tacaccacaa gaaatctcag caatgatcct tcaatatatc aaaggattcg cagaagacta
     8821 tttaggtgaa aaagtcgaaa aagcagttat cactgtgcca gcttacttta atgatgcaca
     8881 acgtcaagca acaaaagatg ctggtaagat cgctggtcta gaagtagaac gtatcgtcaa
     8941 tgaaccaact gcagctgctc ttgcctatgg tttagataaa acagatcgcg acgaaaaaat
     9001 cttagtattc gaccttggtg gcggtacttt tgacgtatct atccttgaac taggagacgg
     9061 tgtctttgat gtattgtcaa cagctggcga caaccatcta ggtggggacg actttgataa
     9121 caaaatcatc gactacatgg tagcagaatt caaaaaagaa aacagcattg acttgtctca
     9181 agacaaaatg gctttacaac gcttgaaaga cgctgctgaa aaagcgaaaa aagatttatc
     9241 tggcgtatca agcacacaaa tcagcttgcc atttatcaca gcaggagaat ctggaccatt
     9301 gcatttggaa atgacattga cacgtgcaaa atttgatgaa ttaacagctg acttagtaga
     9361 acgtacaaaa gtaccagtac gtcaagcgct aaaagatgca ggtttatcac aatcagaaat
     9421 cgacgaagtt attttagtcg gtggatctac tcgtatccct gcagttgtag aagcagtacg
     9481 taaagaaaca ggaaaagaac caaacaaatc agttaaccct gatgaagtag ttgctatggg
     9541 tgctgctatc caaggtggcg tgatcactgg tgatgtgaaa gatgttgttt tacttgacgt
     9601 tacaccattg tcattaggta tcgaaacaat gggtggagtg ttcactaaat tgattgaccg
     9661 caatacaacg attccaacaa gtaaatcaca agtattctca actgcggcag ataatcaacc
     9721 agcagtagac atccatgtat tacaaggtga acgcccaatg gctgctgaca acaaaactct
     9781 aggaagattc caattgacag atattccagc agctcctcgt ggtattccac aaatcgaagt
     9841 aacattcgat attgataaaa acgggattgt aaatgtatct gcgaaagatc taggtacaca
     9901 aaaagaacaa aaaatcacga tcaaatcttc ttcaggtcta acagacgaag aaatcgaacg
     9961 tatggtaaaa gatgcagaag caaatgcaga agcagataaa gctcgtaaag aggaagttga
    10021 cctacgtaat gatgtagatg cattgctatt ctctgtggac aaaacattga aagaattaga
    10081 aggcaaagtg gacgaagaag aagtgaaaaa agcagaaaca gctcgcgatg aattgaaagc
    10141 cgctgttgaa gcaaacaaca tcgaagaaat gaaaactaaa cgcgatgcat tgaacgaaat
    10201 cgttcaaaac ttgactgtta aactatacga acaagcggca caacaacaag ctcaagaaaa
    10261 cccagaagca gctcaaggcg gagcagatga tgtcgttgat gctgattttg aagaagtcga
    10321 tggcgacgat aaataatcag ttcactgaat ttcgagagaa ggccaaagtt gctactttgg
    10381 ctttttcttt tgaaaaatag tttgaagtat cggtttttgt ttcaaacaaa atatgatatg
    10441 ataacaagcg acgtgaaaat gatgagaacc aataggagga aagcctatgg caacaaaacg
    10501 tgattattat gaagtcttag ggctctcaaa aggagcatca gaagatgaaa taaagaaagc
    10561 ttatcgtaag ctttcgaaaa aataccatcc tgacatcaat aaagaacctg atgcggaaga
    10621 aaaattcaaa gaagtatcag aagcatatga gattttaagt gacccgcaaa aacgcgctgc
    10681 atatgaccaa tacgggcatg caggcacaga tccaaattac ggtgctggtg gagctggtgg
    10741 cggatttggt ggattcggcg gcttctctgg tggcggcttc ggtggttttg aagatatctt
    10801 cgactctttc tttggaggag gcggtcggtc agtcgatcca aatgcgcctc gtcaaggtgc
    10861 tgatttgcaa tatacggtcg acttgtcttt tgaagaagcg atttttggtg tagaaaaaga
    10921 aatcaagtat aatcgggaag aaatctgtca tacttgtggt gggaacggtg caaaaccagg
    10981 cacacaacca actacttgtc ataaatgtca tggtgcaggt acgattaatg tagaacgcca
    11041 aacaccactt ggacgagtga tgagccgtca aacttgtgat gtttgtcatg ggacagggaa
    11101 agaaatcaaa gaaccttgtc caacctgtca tggctcagga catgagaaga aagcacattc
    11161 agttaaagtg aatgtaccag ctggtgtaga agaaggacaa caaatgcgtt tagctggtca
    11221 aggagaagct ggagaaaacg gcggaccatt tggtgatttg tatgtggtct tccgtgtaga
    11281 agaaagtgat atctttgatc gtgaaggttc tgaaatttac tatgaattgc ctttaagttt
    11341 tgtacaagca gctttggggg atgaagtcca agtaccaact gtccatggag atgtgaaatt
    11401 gaagatccct gctggaacac agacaggtac gaacttccgt ttacgtggaa aaggcgctcc
    11461 gaagttacgt ggtggtgcaa caggcgacca acatgtcaaa gtaaaactga tcacaccgaa
    11521 aaatctaaat gaacaacaaa gagaagcatt acgtgcattc gctgaagctg gcggcatcaa
    11581 agttgaagaa cagcaagaag acggtttctt cgataagttt aaagatgctt ttggcgggaa
    11641 aaagcggaag tagtttttct agtaaaaacg ctaagtcatt aataattaaa aaccagacga
    11701 acaatcatat gttcgcctgg tttttttgta gttgtcatgt ttgtaccaac aaaaaagcca
    11761 gctttagaat atgataatcg tcatagtttc taggggtata accagtgaga gaatggaact
    11821 tgttcaatcg atattgcaag gtgtttttat gaataaataa ttcttctgag caatttttga
    11881 tgcttccgtt atttttactg aagcatgcca aagtcttctt gaacaaatgt acttcttctt
    11941 ctgtcaggct tttcaaaata cgttttacat ataatgttcg ttgatctgac gggattgctg
    12001 gtaaaacgat cccgaggtct aaatcttcaa aaaagcggat ctcgttcaca gattgatgga
    12061 aagctatcca ttcgcaaact tgtttggcat gaaggaaaga ttgcggtgtc tcttgctctg
    12121 tataacaaag cgacccaatt ccaaagttta gctgtaactg atacatttta ttaaactttg
    12181 tctggatttt atcaagcaat gatagcaatg aggctctgga aatccgattg actaggataa
    12241 tgatttgttg tctatgtaca gtgagcaaag cctgtccgta ataagagaag accctttcga
    12301 gcaactccaa taaaggattg atccgttctt gacacaattg ctgattgtca gaaagttgtc
    12361 ccacaactac ataatatgga gaagaaaaat caagctcaat taagtgaggg tggtatcgac
    12421 tatgtacttg atatcatcaa tgaaccgatg gtactttctt atgcgatgga acaggtagag
    12481 cgattgcttg tttgtgcagg aaaacaagcg atgcggctga tacgattagg tgagaaaata
    12541 agaagataaa aatacacggt cccttcatgg cgaccgtgca tttttggttt ttattaaata
    12601 tttaatactt tattcaagaa atcttttgtc cgttcatttt gcggattttc aaagatttgt
    12661 tgaggcgttc catcttctaa aaagtttccg tcgtcaatga acatgacgcg attggccact
    12721 tctttagcga accccatttc gtgcgtaacg ataaccatcg tcataccttg ttctgctaac
    12781 tttttcatga cgttcaagac atcaccgacc atttcaggat cgagtgcaga agtaggctca
    12841 tcaaaaagca tgatgtcagg gttcatcgct agagcacgag caatagccac acgctgtttt
    12901 tgtccaccag aaagcatttc aggatacata tcttttttat cttctagacc aactgtctgc
    12961 agtaatttga ttgctttttt ctctgcttct tctctagatt ctttcttcag gtccatcggt
    13021 gctaaaatga tgttttccaa aatagaaaga tgagggaata ggttaaagtg ttggaatacc
    13081 attccgatat gttgtctcac caagttgata tctgtgcttt tatccatcaa gtgggcgccg
    13141 tcaataataa tttcaccgtc agaaggttct tctaaacgat tcaagcaacg caagaatgta
    13201 ctttttcctg aacctgaagg gccaatgata cagacgacat ctccttcgtt gatggataca
    13261 ttgatgtcgt ttaatactgt gttatcgccg tattttttga ctaaatgctc aactaagatt
    13321 ttttctgcca tcttacttca ccttcttttc taaaactttt gctaattttg tcaatgctgt
    13381 gatcaaaatc aagtacatga tcgcaatgat caagtaaaca tacgtacttt gtgttgtacg
    13441 tgcaacaatg atcttaccag tttgcagcaa ttcgactaca ccgattgcgg aaatgatcgt
    13501 tgtgtctttt aatgagataa cgaactgatt gacgaatgat gggatcatga tgcgtatcgc
    13561 ttgcggcaaa atgatttttt gcattgtccg attataagaa agacctaaac ttctggaagc
    13621 ttccatttgt ccgacaggaa cggcgttgat cccgcctcga acaatctctg cgatataagc
    13681 acttgcgtta agagtcaagg tgataacacc agcaaggaag tcaggaatcg taaatccaac
    13741 gataccaggc aacccaaaga aaataaagaa cgcaagaacc atcattggaa ttcctcggat
    13801 gatatcgaca taaatactag caattgtgcg aagagcgcgt attggtgcta cactgaataa
    13861 tccaaaaatc acaccgatta ctatagccaa agcaaaggag atcaaagtta ggagaattgt
    13921 tctccaaagt cctttcaaca atgcttgata gttgttttgg ataagtccaa gaaatgttga
    13981 ttcatcagca gtggaagact cactggaagt ttctgaacca tccgctacat attctttaat
    14041 aatcttatcg tattcgcctg ttctttttaa ttctttcaat ccttcattga acatattaag
    14101 aagctcagga ttttgtcctt ttttaacggc aaatgcatat tttccgccag attctttttt
    14161 gatcggtgtt tccaattctt gtccttgttt gatcgcataa ccgattaccg gataatcatc
    14221 catcattgca tcgattgcgc caacttttaa cccgtcgtac aattgatcag cagcatcaaa
    14281 atatttgata gaatagccat attcagattc atggtcgctt aaaaattcag cactttcggt
    14341 accaactttt gctccgactg tttttccttt caaatcttca taagacttga tcgaagtatc
    14401 tccttttttg acagctaatt ggatcccgct atcaaagtaa gaatcagaaa aatcatagct
    14461 tttctttcgt tcatctgtta cagtcattcc ggcaatcatt ccgtctgctt gtcctgattc
    14521 caaagcttgc aaagcagcag agaaaccacg gtagtccatt cggatgttaa atccttgcag
    14581 tttggcgatg ttttccatca attttacatc gatgccttcg tactcgccct ttgcgttttg
    14641 aaattcaaat ggagcaaaag cagagtcact ggcaattacg tatacgtctt ttttgggctc
    14701 tattttttgc attgtctcgc ttgtgcttga ctctgccgtt gtagtgttgt cagcttgtgc
    14761 aacatgacca aacgcaagtg tcacaagtcc tgtcattaag aaaacaaatg agtgaaataa
    14821 atgctttctt ttcataatca acctcctaaa tttccaatat tttattatta taggcgaaaa
    14881 gtgctgaatc agacaagact gtaagctcga aaaaatgaaa aaaatgcgag tttctaacat
    14941 tttatgttat aaaacataac atgtataata agataaaaaa gtggcgaaag tatgttcggt
    15001 gtggtataat tttttagtaa ggaatgcctt tgctttcctt ttctttttat tggtcgtaaa
    15061 atgaaaagga atgaatgaaa aggaggacga agaatgattg agagagatac ctcccgacac
    15121 tttgagcttg tctcgaaata ccaaccggct ggtgatcagc ctgaagcgat taaccaatta
    15181 gtggatggcg tagtcggcgg gaaaaaagca caaatcttat taggtgcgac tggaacaggg
    15241 aaaacatata cgatttccaa tcttattgag aaagtgaata aaccaacact gattattgcc
    15301 cataacaaaa cattggctgg tcagctgtac ggggaattca aggaattttt ccctaacaat
    15361 gctgttgaat attttgtttc ttattatgat tattatcagc ctgaagctta tgtgccttca
    15421 agcgatacgt atatcgaaaa agattcaagt gtaaatgatg agatcgacaa attacgacat
    15481 tcggctacta gttcattatt agaaagaaat gatgtgatcg tcattgcatc cgtttcatgt
    15541 atttttggat taggctcgcc ttttgagtac caaaaacaag tagtttcgat tcgacaggga
    15601 gcagaactag atcgcaatca gttgattcgt gacttagtca gtatccaatt cgaaagaaat
    15661 gatatagatt ttcagcgcgg tcgttttcga gtgcgcggtg atgtcgtgga gatttttccg
    15721 gcttcaagag atgaacgtgc cttacgtgtg gagttttttg gagatgaggt cgaacgtatc
    15781 cgagaagtca atgcactgac aggtgaagtt ttaggagaaa cggaacacgt agcaatcttc
    15841 ccggcgactc actttgtgac gaatgatgaa catatggagc atgccgtagc gaatatcaaa
    15901 gcggaattag aacagcgttt aactgtcttg cgaaatgaaa acaaacttct ggaagctcaa
    15961 cgtttagaac agcgaaccaa ttacgatatt gaaatgatgt tagaaatggg ctacacgtcg
    16021 ggaattgaaa attattctcg gcatatggac ggacgtaaag aaggtgaacc gccttatacg
    16081 ctattggatt tctttcctga agattttttg atcgtggcgg acgaatcgca cgtaaccatg
    16141 cctcaaatca gaggaatgta taatggtgac cgagcgagaa aacagatgct agtagattac
    16201 ggtttccgtt tgccatctgc tttagacaat cggccacttc ggttagaaga gtttgaaaaa
    16261 catgtcaatc agatcattta tgtctctgcg acgccaggac catatgaaca tgaacaaaca
    16321 gataccgtta tccaacaaat catccgtccg acagggctgc ttgacccagt gatcgaagtt
    16381 cgtccaatca tgggacaaat cgatgatcta gtaggcgaaa taaatgaacg agtcgaaaaa
    16441 gaccagcggg tgtttgtaac gacattgacg aaaaaaatgg cagaagacct cacagattat
    16501 ttcaaagaat tagggatcaa agtcaaatat ttgcatagtg atatcaaaac gctggaacga
    16561 acagaaatca ttcgagatct tcgattaggt gaatttgatg tgttagttgg aatcaatttg
    16621 cttcgtgaag gattagacgt acctgaagtt tcccttgttg ctatcttgga tgcggataaa
    16681 gaaggctttt tacgtagtga acgttcctta gtccaaacga ttggacgagc tgctcggaat
    16741 gaagaaggta aagtaatcat gtacgcagac aaagtaacag attctatgcg tctagcgatg
    16801 gatgaaacgt caagacgtcg tacgattcag cagaagtaca atgaagaaca tgggatcgtt
    16861 ccaaaaacga tcattaaaga aatccgagat ttgatttcta ttacgaaaga atcggaagat
    16921 gatacaaaag aagcggtaca agtctcgtac gaagaaatga cgaaggaaga aaaagacacg
    16981 ttattgatga aattagaaaa agaaatgaaa gatgcggcaa aagctttgga ttttgaaaca
    17041 gccgcgaatg tgcgagatat gattttagaa ttaaaagctt caaagtagga ggacaacatg
    17101 gctaacgata aaattacgat tcatggtgca cgtgcccata acttgaaaaa tatagatgta
    17161 acgattccac gagataaatt cgtggtcgtt acaggtttgt ccggttctgg aaaaagttcc
    17221 ctagcatttg atacgctgta cgctgaaggg cagcggagat acgtagagag cctttctgct
    17281 tatgctcgtc agtttttagg acaaatggat aagccggacg tagatagcat cgacggattg
    17341 agtccggcga tttctattga tcagaaaaca acaagtaaaa atcctcggtc gacagtaggt
    17401 actgtgacgg aaatcaatga ctatttacgc ttgttgtttg cacgtgtagg acatccgatt
    17461 tgtcccaacg atcatatcga gattaccagt caatcagtag atcaaatggc agatcaagta
    17521 atggctttgc ctgagcgcac aaagatccaa gtgttggcac cgatcgtggt aaagaaaaaa
    17581 ggacaacata aaaaaatatt cgaacgaatc caaaaagagg gatacgtccg cgttcgagtc
    17641 gatggtgaga tctatgattt aagtgaagtg cctgagctgg agaaaaacaa aaaacatgat
    17701 atcgcgatcg tcatcgaccg gatcattgtg aaagaaggga ttcgttctcg cctatttgat
    17761 tctttagagg cggccctgcg attagcagac ggctatgctc tggttgacgt gatcggtgaa
    17821 gaagaaatgt tgtttagcga acactatgcc tgtccttatt gcggatttac tgttggcgaa
    17881 ctagaaccaa gactgttctc attcaatgcg ccttttggag cttgtccaga ctgtgatggt
    17941 ttaggtgtca aattagaagt cgatcaagat ttagtgattc cagatagaac gaagacactt
    18001 agtcaaggtg ctatcgttcc atggaatcca atcagctctc agtattatcc tcaaatgtta
    18061 gcgcaggctt gtgaaagttt cggtatcgat ttagatacac cattcgaaga attaccggaa
    18121 gagcatcagg agatcatctt gaatgggaca gatgatcttt tccatttcca ttatgaaaat
    18181 gattttggtg gcgttcgcga tgtagaaacg actttcgaag gggtattgaa gaatatcgag
    18241 cgtcgttatc atgatacgaa cagtgatttc acgcgtgagc aaatgcgtct ttatatgaca
    18301 gaattaactt gtcagacatg taaaggttat cgattgaatc cccaagctct atctgttcaa
    18361 atcaatggaa cgaatatcgg gcaaacaaat gagttgtcta ttcaaaaagc agtagatttc
    18421 ttctcaaact taacgttatc tgaacaagag aaagtaattg ccaaaccgat tttaaaagaa
    18481 gtaaatgaca gactttcatt cttggaaaat gtgggactag actatctaac tttgagtcgc
    18541 gcttccggaa cattatctgg gggagaagcg cagcgaatca gattggctac acaaattgga
    18601 tcgaatcttt ctggagtttt gtatatttta gatgaaccat cgatcggatt gcatcaacgc
    18661 gacaacgatc gactgattgg ctcattaaag aaaatgcgtg atcttggcaa caccctcgtt
    18721 gtagtcgaac atgatgaaga tacgatgtgg gcagcagatt atttgattga cgtcggacct
    18781 ggggccggag aacaaggcgg acaaatcgtg gctgcaggca ctcctgaaga agtagctaat
    18841 gatgaaaatt ctttgacagg gaaatatctt tcagggaaaa aatcaatccc tgtaccaaaa
    18901 gaacgccgta aaggtaatgg gaaagcaatc aagatcactg gtgcttcaga aaacaatctg
    18961 aaaaatatta gtgttgaatt tccattagga gaatttgtag cagtcacagg tgtgtctggt
    19021 tctggaaaga gtacattggt caatagtatc ttaaagaaat cgttagcgca aaaattaaat
    19081 aagaattctg ctaagccagg taaattcaag acaatttccg gctacgaaag tatcgaaaag
    19141 atcatcgata tcgatcaaag cccaatcggc cggacgccga gaagtaatcc agcgacttat
    19201 acaagtgtat ttgatgatat ccgtgggtta tttgctcaaa cgaacgaggc aaaaatgcgg
    19261 ggttataaga aagggcgttt tagtttcaac gtaaaaggcg gtcgttgtga agcttgtcgc
    19321 ggggatggaa ttattaagat cgaaatgcac tttttgcctg atgtctatgt tccttgtgaa
    19381 gtatgtcatg gtaaacgata taattctgaa acattagaag tgcattacaa aggaaaaagc
    19441 attgctgata ttttggaaat gacagtagag gatgctgtag aattcttcaa gcacattcca
    19501 aagattcatc gcaaactgca aacgattgtt gatgttggct taggttatgt gacgatgggg
    19561 caaccagcaa cgacattgtc cggtggtgag gcacaacgga tgaaacttgc cagtgaattg
    19621 cacaaaatct ctaatggaaa gaatttctat atactagatg aaccaacgac aggacttcat
    19681 agcgatgaca tcgcccgctt gttgcatgta ttacaaagat tagtagatgc tggtaacaca
    19741 gttttagtga ttgaacacaa tctagatgta atcaaaacag cagattatat cattgattta
    19801 ggaccagaag gtggagaagg tggaggaacg atccttgcga ctggaacacc agaagaaatc
    19861 attaacgtaa aagaaagtta tacaggtcac tatttgaaaa aaataatggt ataaagagga
    19921 tagatagctg agatagttaa aaaaacataa aaaaatgaat ttttgcttgt tttattaata
    19981 tcagtgttct agaatcatta catggtagtt ctttctacac tgattggtat agataaaaac
    20041 ttcctataag ttcaatccgt tcaaaaaaga attgagcaat cggaggagtt tcctttgatt
    20101 gcttttttct ttatggtatg atattccttg tgtagttgga aaagaaaaac aagagattat
    20161 gagtaagtga gagataatga tgaacagtat tgaaaatgaa gaatttatcc ctatattatt
    20221 aggaagcgac atgaacgttt atggtatggc acgttctttt aatgaagcat acggcaaaat
    20281 ctgccaagca tatgcttcgg atcagttagc ccctacccgc tacagtaaaa ttgtcaatgt
    20341 agaagttatt ccaggatttg ataaagaccc tgtatttatc gagacgatgc ttcgtttggc
    20401 aaaagaaaga tattctgata agagtaaaaa atatcttttg attgcttgtg gtgatggata
    20461 tgcagaattg atctcccaac ataaacaaga gctgtcagaa tattttatct gtccatatat
    20521 tgattattct ttatttgaaa ggctgatcaa taaagtaagc ttttatgaag tttgtgaaga
    20581 atatgatctt ccgtatccta aaacattgat cgtcagagaa gaaatgttag taaatggaca
    20641 tttggaacag gaattgcctt ttgaattccc agttgctttg aaacctgcaa acagtgtgga
    20701 gtatctttct gtccaatttg aaggaagaaa aaaagctttt attttagaga ctagagaaga
    20761 gttcgattta attttaggcc ggatatacga agccggttat aaaagtgaaa tgattgtaca
    20821 agattttatc ccgggtgatg atagtaatat gcgtgtgcta aatgcgtatg tagatgaaga
    20881 tcatcaagtt cggatgatgt gccttggtca tccactatta gaagatccta caccagcatc
    20941 gattggtaat tacgttgtga tcatgccaga ttataacgaa aaaatctatc aaaccattaa
    21001 ggcatttttg gaaaaaatcg aatatacagg ctttgccaat ttcgatatga agtatgatcc
    21061 tagagatgga gaatataaat tatttgaaat caatttgaga caaggtcgta gcagtttctt
    21121 tgtgacattg aacggcttga atctggctcg ttttgtcaca gaagatcgag tgttcaacaa
    21181 accctttgtt gaaacgacct atggaacgaa tcaatcagat aaagcaagat tatggatggg
    21241 tgtgcccaaa aaaatctttt tagaatatgc tcgggaaaat gaagacaaaa aactagctga
    21301 gcaaatgatc aaagaaaatc gttacggtac tactgtattt tatgaaaaag accgatcaat
    21361 caagcgctgg ttgttgatga aatatatgtt ccataactat attccaagat tcaaaaagta
    21421 ttttcatgtg aaagaaggct agttcatgga gaattttttc agtattttag gcggaatggg
    21481 cacgatggcg acagaaagtt ttgttcgctt gatcaaccac cgaacgaaag ctacaaaaga
    21541 tcaagaatat ttgaattatg tcttattcaa tcatgcaaca gttcctgatc gtacagctta
    21601 tattttagat cgatcagaag aaaatccaat gccgtttctg ctggatgata ttgagaaaca
    21661 aaatttattg cgaccaaact tcattgtgtt gacttgtaac accgcacact acttttttga
    21721 agagttacaa gcggcaacgg atattcctat cttgcatatg ccaagagaag cagcaaatga
    21781 acttgtccgt cagcatacga cagggagagt agcgattcta ggaacagaag gaagtatgaa
    21841 agctggaatc tatgaacgcg aagtcaaaaa tcttggtttc gaaacagtga ttcctgatac
    21901 tgcgcttcaa gaaaaaatca attacctgat ctatcatgag atcaaggaat cggattattt
    21961 gaatcaagag ctctattacg aaatcttaga ggaagcggta gagcgcctaa actgtgaaaa
    22021 agtcatccta ggttgcacag aattatcttt gatgcatgaa tttgctgaag ataatcatta
    22081 cccagtgatc gatgctcaat ctattttagc ggatcgaacg atcgaacgtg cattagctga
    22141 aagaagcgag gcattggata cagcatcgga aaagtaaaaa aattggattt ggggcaaata
    22201 tcctaaaaga tatttggtcc aaatcttttt gtaaaagaaa aagaaaactg gtaatgatac
    22261 gcccgggatg atataatttt attatgcaca atgtgagagg ggttcgtaaa tatgacagat
    22321 aatttgcaat tagtcatcat aacaggtatg agtggtgcag ggaaaacagt agctatccaa
    22381 agttttgaag atatgggcta tttttgtatc gataatatgc cgcctcgatt gattccaaaa
    22441 ttctgggaat tgatcaaaga atcaggtaaa gtcacaaaaa tggctttagg agtggatttg
    22501 cgttctcgtt ccttctttga agaaatccaa aacatgctga tcgaaatcga aaatacgaac
    22561 ttcatcgaca cttctatctt atttttagat gcttcagacg aagaactagt ggctcgctac
    22621 aaagaaacaa gacgagcaca tccaatggcg atggacggtt tgatcactga agggatacgt
    22681 aaagaacggg cgatactaga cgacttgaaa gcccaagctt ccgtgatcat tgatacgaca
    22741 acattgacac cacgacaatt acgtgaaaaa atcaatgagt cattcaaatc aaagggagac
    22801 caaggatttc ggatcgaatt tgtatcattt ggttttaaat acgggttgcc gatcgattcg
    22861 gatattgtga tggatgtgcg ttttttgccc aaccctcatt atatcccgga actaagacca
    22921 ttgaccggaa aagatcagcc agtctatgat tatgtgatgt cctttgatga aacgcaatca
    22981 ttctaccata aatttttgga tcttctggaa actgtattgc ctggatacat taaagaagga
    23041 aaaagcagct tgacagttgc aatcggctgt acaggcggtc aacaccgttc tgtggcattg
    23101 actgaacgtt tggcaaatgc tttagggaaa aactataaag tcaatgtgac acatcgggac
    23161 aaggataaaa ggaaagagac ggtgaaccgg tcgtgaaaat gaaaacctac cggataagaa
    23221 aaccaaagat cgtagtggtc ggcggtggca ctggtctgcc agttatcctg aaaagtttac
    23281 gaaatcaagg agcagatatc acagcagtag tgactgttgc agatgatggt ggaagcagcg
    23341 gtgcaatcag agaatcgatc gctatggctc ctcctggtga cttgagaaat gtcttagtgg
    23401 cgttatcgga tatgccacaa ttctatgaag atattttcca ataccgtttc aaaaaggaag
    23461 atcagttttt agccaatcat acgatcggta atctgatcat tgccgcagtt tccgagatgc
    23521 ggggaagcac ttatgaggcg attcaattat tagcaaaaat gatgcatgta gatggacatg
    23581 tttatccttc ttcagaaact cctttgacct tgcatgctgt ttttaaagac ggaacgactg
    23641 cagtaggaga atctaaaatc gcgatcaacc gtaaaaccat tgaccgtgtg tatgtctgca
    23701 acacaaatga taaaagtgaa gccaaagcgg ctcgaaaagt cgtttcagca attatggacg
    23761 ccgacatggt cgttttggga cccggaagtt tattcaccag tatccttcca aatttagtga
    23821 taccagaaat cggcgaagca atgctcaaga caactgctga aaccgtctat atctgtaata
    23881 tcatgaccca aaaaggggaa acggaacatt tcacagatgc cgatcatata cgtgttttac
    23941 acaagcattt gaatcagcct tttatcgata cagtattggt caatacggaa aaagtgcctg
    24001 aagattatat ggacccagag atctatgatg agtatctagt acaagtcgca cacgacttca
    24061 acggattgag aaatgaagga tgtcgagtga tttccaccga ctttttagaa ttgaaagatg
    24121 gtggtgtctt ccacgatgga gacaaagtag tagaagaatt gttccgttta gttttcggtt
    24181 caaaatatta agcaatttat tgttggagaa aggaggagaa taggatgtca tttgctgcag
    24241 atgtgaagaa agaactaact ggtttggaag ttcatcgaga acatgcgaaa gcggaattag
    24301 ctgctttgct gcgaatgaac ggctctttag gtattgtgaa ccagcagttt attttgaacg
    24361 tccaaacaga aaatgctgca attgccagac gtatctattc tcttttgaaa gatcattatc
    24421 aggtacgaag tgagctactc gttcgtaaaa aaatgaaatt aaaaaagaac aatgtctata
    24481 tcgtccggtt gaagcaaggc acaaaagatg tgttgatgga tcttgatatc atggatggta
    24541 tgatgttcaa tggacacgtt tcggacgaga ttatgggaaa ttcgcaaaaa atgcgttctt
    24601 acttacgtgg tgcttttatg gcctcaggtt cagtcaataa tccggaaacg agtcgttatc
    24661 atttggaaat attttctatt tatgaacagc ataaccaaga catttgcgat atgttaaatt
    24721 attacggtct acatgctcga acgcttgaac ggcgcaatgg ctatatttcg tatttaaaag
    24781 gagcagaaaa aattgctgat ttcttaacat tgattggtgc aaccaactca atgctccgat
    24841 ttgaagatgt tcgaatcgta cgggatatga gaaattcggt caatcgtcta gtcaattgtg
    24901 agacagcaaa tctgaacaag acgattgatg cggcttctaa acaaatcgaa aacatcgaat
    24961 tgatcgaagc aaaggtcggt ctacatgccc ttcctgaaaa acttcaggaa atcgcagaac
    25021 ttcggcttca acatccagag gtcagcttga aagaattagg ggaaatgatt ccctcaggtg
    25081 caatatcaaa atcgggaatt aatcaccgaa ttcgcaaaat aaatgaattt gcggaaaaac
    25141 tgcgtgaaga agcagtttaa tccaaagaaa aaactgatac atgaagcagg agatgcgaat
    25201 gtatcagttt tttttaaaag ctatacttgc ttttcttccg tcaaactata attccaactt
    25261 tactggagta acataatgtt gaaaggcttc tattgttttt taatacaatc gtataaaaag
    25321 cggggagaca actgaatgaa gattttagtt ttatacataa acttttgctt aatatagaag
    25381 tcctgatata gataggatca agtatttatc tataactgga gattaattaa aaactggaag
    25441 gaactgctcg atcaaccttg agaactgttt ttcttacttc tggtcaagat tctcgtggtt
    25501 ggtggataag gatggttgat aagttcattg gattagctag tcgaaaacaa ccaggtgtaa
    25561 ttaatgtaga agttttaaca aggggatgga gtgatttatt cagtgataat cataagttca
    25621 taaatagtaa ttgggatgta tggttggtat acgttatacc tgaacttgaa ctatcaagat
    25681 ttggtttaga atttgagaat cgatgtttat aaagggaggg caaaaaatgt gcttttttac
    25741 aacttttact atcattatga ttgcagtact ttttattttt ctagatatag caaagcgaaa
    25801 tacagcattt ttattatatc gggttttact tcgagcaggt ctcataacat ttatatcgat
    25861 cgttggattt tttctattca cagttattgt atttatttgg agaactacag caccaccatt
    25921 gccagagatt acatatggag aatttccgtt tagtcttgaa tatgaaatag atgaggaaag
    25981 aattttgatt gaagatacgg tgattgcaga atttatagga agttttagag ggaatgtgac
    26041 aactcaacct agacgaagtt ggagtataaa acttttaaat aatagtggag agttgaaagc
    26101 atttcattat gaattcttaa taatagaaag tgaagatgta acaatcactt taagtagtgg
    26161 ctctgctgga tattttatga atgatggtgg aagcaagcca cagctcacag tccgtgatcg
    26221 tattgcaggt tttatgcatt tttctcacta tgacttagaa gaagctcgta aaatacttgc
    26281 agaatatggg atcacattaa tcaattggga atatgcgcca ccgataagaa attttttcaa
    26341 tgattattat tagtcttata aaaaacagaa tgtaaaattt atgtgcgcga gtatttagtt
    26401 ttccattttt tgtttgatag atatatagca ttgttgaagc atgggatagt ggtgccaatt
    26461 ttatcaatga ggttggtcag gcagttaaca taattggtga tgctataaat ccatttaatt
    26521 ggaattggag gaattaggtg tggaaacagt gagattatgg atattcatga aaaattttcg
    26581 ttcggctttg agatatgtta ttctggaatc aaaatcaggt tattatctga ttgacacaga
    26641 tcactatact ttttggggag gctacctttt tccgattttt aattggataa tcccccataa
    26701 ggttatgaaa attaacttgc ctgcagaaga aataaataga ttaatactca acaaagattt
    26761 acaaaggaaa agagagaaag aacattctaa tgttgcttgg ataggtccag catttgcagt
    26821 agtgacttct tcaattgtcg gtcctatgct agagagtatt tatagtgatt tttctattgg
    26881 aatacgttat ttatttgtta ctttaagtat agctgttctt ttgtgcataa agggttatgt
    26941 tagcaagaag aataaagata ttttaacact aatcggtgta aacaatttat ctagtactaa
    27001 aattatactg tttcctgaat ctataaaaga aggatcaagg ttgttgataa tttttataat
    27061 gcttatactg ttttctgttt tatttggggt gatgtttata g
//
LOCUS       DAKCAA010000035        27039 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000035 DAKCAA010000000
VERSION     DAKCAA010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.035"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            73..690
                     /locus_tag="OUE31_001625"
     CDS             73..690
                     /locus_tag="OUE31_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222638.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
     gene            1710..2879
                     /locus_tag="OUE31_001626"
     CDS             1710..2879
                     /locus_tag="OUE31_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCU0222639.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            3352..3906
                     /locus_tag="OUE31_001627"
     CDS             3352..3906
                     /locus_tag="OUE31_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCU0222640.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(4079..4552)
                     /locus_tag="OUE31_001628"
     CDS             complement(4079..4552)
                     /locus_tag="OUE31_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCU0222641.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            4564..5100
                     /locus_tag="OUE31_001629"
     CDS             4564..5100
                     /locus_tag="OUE31_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCU0222642.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            5140..5511
                     /locus_tag="OUE31_001630"
     CDS             5140..5511
                     /locus_tag="OUE31_001630"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCU0222643.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            5795..7066
                     /locus_tag="OUE31_001631"
     CDS             5795..7066
                     /locus_tag="OUE31_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCU0222644.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            7311..8336
                     /locus_tag="OUE31_001632"
     CDS             7311..8336
                     /locus_tag="OUE31_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0222645.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            8630..9739
                     /locus_tag="OUE31_001633"
     CDS             8630..9739
                     /locus_tag="OUE31_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCU0222646.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            9822..10718
                     /locus_tag="OUE31_001634"
                     /pseudo
     CDS             9822..10718
                     /locus_tag="OUE31_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            10734..11558
                     /locus_tag="OUE31_001635"
     CDS             10734..11558
                     /locus_tag="OUE31_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCU0222647.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            11590..12900
                     /locus_tag="OUE31_001636"
     CDS             11590..12900
                     /locus_tag="OUE31_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HCU0222648.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            13048..14307
                     /locus_tag="OUE31_001637"
     CDS             13048..14307
                     /locus_tag="OUE31_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCU0222649.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            14317..15189
                     /locus_tag="OUE31_001638"
     CDS             14317..15189
                     /locus_tag="OUE31_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0222650.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            15201..16031
                     /locus_tag="OUE31_001639"
     CDS             15201..16031
                     /locus_tag="OUE31_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCU0222651.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            16071..18254
                     /locus_tag="OUE31_001640"
     CDS             16071..18254
                     /locus_tag="OUE31_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCU0222652.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            18315..19535
                     /locus_tag="OUE31_001641"
     CDS             18315..19535
                     /locus_tag="OUE31_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HCU0222653.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            19532..20992
                     /gene="gtfA"
                     /locus_tag="OUE31_001642"
     CDS             19532..20992
                     /gene="gtfA"
                     /locus_tag="OUE31_001642"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HCU0222654.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            21069..22175
                     /locus_tag="OUE31_001643"
                     /pseudo
     CDS             21069..22175
                     /locus_tag="OUE31_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            22497..22706
                     /locus_tag="OUE31_001644"
     CDS             22497..22706
                     /locus_tag="OUE31_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCU0222655.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            22699..22848
                     /locus_tag="OUE31_001645"
     CDS             22699..22848
                     /locus_tag="OUE31_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HCU0222656.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            23002..23667
                     /locus_tag="OUE31_001646"
     CDS             23002..23667
                     /locus_tag="OUE31_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCU0222657.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(23951..25036)
                     /gene="xerS"
                     /locus_tag="OUE31_001647"
     CDS             complement(23951..25036)
                     /gene="xerS"
                     /locus_tag="OUE31_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HCU0222658.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            25370..25603
                     /locus_tag="OUE31_001648"
     CDS             25370..25603
                     /locus_tag="OUE31_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HCU0222659.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            25600..26007
                     /locus_tag="OUE31_001649"
     CDS             25600..26007
                     /locus_tag="OUE31_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCU0222660.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(26458..26967)
                     /locus_tag="OUE31_001650"
     CDS             complement(26458..26967)
                     /locus_tag="OUE31_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222661.1"
                     /translation="MKKVLFAVSLVVNIALAGGLFYTITEMNKLDDQRESLAISNEQY
                     KRKLDEASSTNVDTQEAVESSTIVYSNESSETLTNSERSTAPATETVSQKATITIGSK
                     VFTFIVNGLTIEHDSSRTGKMTELSHEFPVIVTTPSATLNGILVQDNNDNNCYIMVDG
                     QTLYRGTYQ"
BASE COUNT         9294 a         4020 c         5033 g         8692 t
ORIGIN      
        1 taacagccta agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca
       61 gaaccgagaa ccttgggttt tcaagtgctt tttggttcat taatcttaac catagtgttt
      121 ttaaagtgga aaacaagcaa caaaaaaagt atgtggagcc ttgtaggaat agttcttatt
      181 atttttactg tgactgcagc aacagaagca aattattcgc ataaaattca gtcgtataaa
      241 ggtcgtttag ttatgaccaa aaaagatgtt acacgttata catcctcaag aactggaggc
      301 ctatatgact atgcaccatt agatgcattg aaatataaag atcatttaaa gaaacatgaa
      361 gtaaaagttg gtgatcggtg ggagaatgca tctcataaag catataattc caaaatagtc
      421 tatacagtag aagatgccga tgagcaaaat atcacattac ctgtattcaa ttattgggga
      481 acagttgtga aagtaaatgg gaaaaagagc actatagaaa atgacaatgg tttagtgtct
      541 attaaaggta cggggaaaag aactatagtt gaggtttcat ctacgtatcc aactacgatg
      601 attctatctt tattaattag ttcaataact tttatattct tatttacacg ttatttaata
      661 agatgctgcg gtgaaatgaa aatagattag atagatatta taaatatgtt gattctattt
      721 tcatagcaat ggagaaaata cattagcaat atataaaaga aggtatcaag agtcacagtg
      781 aatttattcc gaaaagtgaa aagagcaaat ataaaattta atgaaaatat agaactaaat
      841 aggaaaacgt agacgtaatt ttctacgttt tccttttcat atatattaaa tattacggaa
      901 aattatataa actaatttag tgttttgttt gtaattccta attttgctcc acttttagat
      961 aatttttagg tctatttaac tcatcagaca ttctatgctc atttttctcc aaatttgttt
     1021 caactctttc gtacttaatt ttgcgtattt gaaaattctt cttttagagt acttttatta
     1081 cgatactagt atgatatata tctatagcaa acagttaaaa tcttcctaaa ataagcgaat
     1141 agcattccta aaacctataa aatttttaga tgaagcgaca agtggacaat taataaacta
     1201 cttgaacatg aaattatgga tcacctttca aatttagaaa atggaattct tatacttatt
     1261 gcgcaacatt tattgattgc aaaattatgt gacaaaaaaa actagtagaa gaaagaataa
     1321 tggcttgata ataaagtact acctattaaa ggtagtactt tatttaattt agtataaatt
     1381 aacatactac tatattttag gtttcatatt atataaatta ataatatact accatttgtt
     1441 ggtagtataa tttaaaggta ataagttatt cttttattac tatgtttggg ttttatagca
     1501 aagaaagttt aataagagtt tggacctagc aaacaatatt aatgaggtca ttaaatctta
     1561 ttatctttag tgatataacg aaatatctac acagacaaaa tgatagcgta aaatattttg
     1621 tgtaaataga tatttagggt agaaaaaaag aaagtccatt ctgtaaaatt aaagttacca
     1681 caaccgaaat tttataggag gactttctca tgcccaattt tactacagaa attatggaaa
     1741 cactaatcaa taaaggtgat ttagatgaat tatttcgatg tcatttagaa ttagctgtta
     1801 attcattatt gcaggctgaa ttaacagctt ttcttgatta tgaaaaatat gatcgtgctg
     1861 ggttcaattc aggtaattcc cgtaatggga attattcacg ttcattcaga acagagtatg
     1921 gagaattaaa tttggtaatt cctagagata gaaatggtaa gttttctcaa caaactttac
     1981 ctgcttataa aagaaccaat gactctttag aaaccactat tattcagcta tttcaaaaag
     2041 gaattactat gtctgaaatc tctgaattga ttgaaaaaat gtacgggcat cactatacgc
     2101 cacaaaccat ttcaaatatg actaaaatag tttctgaaga tattattgcc tttaaagaaa
     2161 ggtccttaga atccagatac tctgtcattt ttatggatgc tactcacatt cctttaaaaa
     2221 gacaaactgt ttcaaaagaa gcagtttata ttgtaattgg cattcgatta gatggaacca
     2281 aagaggttct tgggtttagt cttgctccaa ctgaatctgc ttatgtttgg aaagagattc
     2341 ttcaagacct aaaagaccgt ggtttaaaag aggttttatt agtcgtaact gatggtttaa
     2401 gtggcattaa cgatagtatt catagtgttt atccaaatgc tcaatttcaa caatgttgtg
     2461 tccatatatc tagaaatatc gctcataagg ttcgtgttag tgatcgacaa gaaatctgta
     2521 gcgatttcaa attagtttat caagcaagtt caaaagaaga agcaaataat caaataaggt
     2581 ttatgataga taaatggaaa aagcagtatc cacgagtggt taaattgctc atgaatcctg
     2641 ctatattaac cttttataat ttccctccgt caatcagaag aactatttat tcaactaatt
     2701 tgattgaagg ttttaacaaa caattaaaga aatataccaa aagaaaagag caatttccta
     2761 atgaagaatc tctggagaga tttctagtat ctcaattcaa caactataat caaaagtttc
     2821 tatgccgagt tcataaaggt tttaaagaaa tacatgatac attagaatca atgttttaac
     2881 ttgatcaaca gaatgggctt ttccatttac acaaaattat tgacgctccc gacaaaatta
     2941 tgatcttgcg taaagttata aaatattaat aaaaatattt tattaatgaa aagcttggta
     3001 gcacggttat tcatatgcta atttatttca ctttatagta aggggagttc ttagtatatt
     3061 gttcaaactt aaatttcata taatttaatt atgtaaatta gctattctaa gaacttctac
     3121 ggataactgc ccgtctaaaa tttaaataag agcttagaat cttcatataa gtaaggttaa
     3181 tttttttgta caaaaaagtc ggaatattct gagttactga aatgatataa aatcataaac
     3241 taaatccctt gattttattg actttcaaaa gtttatatat ataagttaat gattatggta
     3301 aaatatatac ataatcatta actcagaata tttttaagaa gggaaacaat agtgagctat
     3361 aatgtacaac cgttaaggac aaatgaagag atacaagatt ttcagttttg gctaagaaga
     3421 acaagtaatc cggaaagaga tagtttttta tttttgtttg gaatcaataa tgggttacgt
     3481 atgtcagata ttataggatt aaaagttgga gatatacgag gcaaaagtaa gcctattatt
     3541 gttgaacata aaacaggtaa gcgaaaaccg atttttatag ataatttgag agaagaaatt
     3601 ttattatata ctgaaggtaa agaagaaaat gattggttat ttccgagtcg gcaacaaggt
     3661 cgacatataa caagggatcg tgtctatcag atatatgcag atatagcaga aaaattagga
     3721 cgagatgata taggaacaca tacattaaga aaaacttttg ggtatcacta ctacaagaaa
     3781 actagagaca ttgctacctt aatgtttatt tttaatcata gctcgcaagc aattacaaaa
     3841 aggtacattg gtataactga agatgaaata ggagcatcac ttcgtggatt taaactaggt
     3901 gtataattta aaaattttta taaacagtaa agacaaagat taaaagctat ttttatctag
     3961 aacgatttta tttcataaag ttcgcggaat aaaagctggg gttactggta cttggtatag
     4021 gttcgtgtta tataaactaa gtaattaaat aacattttta ggttggaaaa ggatgaaatt
     4081 aaaaaaagag aatcaatacg gtctcaaaaa cgcaaacgct gcggaataag aaaaatactg
     4141 ataactcaac gtttagcaga ctatctaata gggatagtct gcttttttcg tttttgacca
     4201 tacttttgac cttctgcaaa cttccttgct tttcctctgt agaactcatg aaatctgcaa
     4261 aacgaattgc cgtttcctct gtctgctttt tcgcgatatg ggtgtatata tcatccatag
     4321 tggttttaat atctgtatgt ccaagtcgaa catacacttc tttgacagac gcaccagatt
     4381 caaagagcag actacaatgg gtatgacgaa aaccatgaag tgtgatatgt tttaagttat
     4441 tctctttaat gatgattttc aaattgtgat ttacatagtc taaataaagg ggcttatttt
     4501 cttctgatga aaacaaaagt tgttcaccat cttttatagg tttgattctc atttttagat
     4561 attatgcccg cacgtattca tcacatttct attgtgaatc gctttattcg accgacattt
     4621 gacttttatc ataatatact cggtttaaaa ttactaatga aaacaattaa tcaagacgat
     4681 cataccatgt atcacctgtt tttttcagat aatcaccacc gtgtgggaac tgaactgact
     4741 ttttttgaag tacaagaagg gaacaaccag ttttttggaa ccaatacgat tgaacgaacg
     4801 atactaaaag ttccttccga agcatcattg catttttggg aaatatattt tgaaacacaa
     4861 ggcgtttgcc attatggaat cgaatcattt tctggacgac ctatcttacg ttttgaaggg
     4921 ccagatgcaa cacgattagc tttagttccc ttacgcgaat ttgaagatat tgatgattat
     4981 ttcccgtatg tcacagacca gatccctaca gagcatgcca ttttaggaat tgatgccatt
     5041 caactacgcg tacaatattc cgatgcgact gaacgagagt tattgtcggt aggctggtag
     5101 cacaaagaat acgtcagttt cttttcgggt catcaacgag tgacaatctt agaaaatcaa
     5161 gacactcagt tctatcaaga agttcagatt attcaagatc gtgagaatcc agttgccatt
     5221 gaagggattg gtagcgtcca tcatgttgcg tttggcgtag aaaataaatc tgatttacaa
     5281 cgcatcgaca aacaattaca agagcgcaat tttataaatt caggaataaa agatcgtgaa
     5341 ttttttgtat cactttatta tcgtgaccca aatcaattat tgattgaaat tgctacaggg
     5401 gaaggaaacc tagatgcaaa agcgtatgaa aatcaaagtc cacgctttga agaaattcct
     5461 ttatttttac cgcagtactt aaatttcatt cgtgaacaag tggagcaata attagctaat
     5521 caaatccatg acgaagagta agaggttgac tcataagtca aaaaataaag aaaaacgcat
     5581 caaatccatt ctaaagaatg ttgatttgat gcggttccta tttttataaa ctatcatttt
     5641 cgactaataa aactacttat gagtcagcct ctcttttttt cttgattttt atacctcttt
     5701 ctaggtaaac taaacatctg ccaaaaatac cgtgtctcat tgaaacattc tcaactattt
     5761 caaaataaag gggagtacca aatgaacgag tatattgaaa ttatccacgc aagagaaaca
     5821 acttaaaaat gtcagtctca aaattcccaa aaataaaatt agtattttta ccagcgtatc
     5881 tggttcagga aaatcatcga ttgtttttga tactattacc caagaagctg gtcgtcaact
     5941 gaatgacacc tatgatagtt ttacccgttt atttttacct aaatacagtc gtccagaggt
     6001 tgatgagatt gataatcttt ctacggcgat tgtggtcaat caaaagaaga ttggtggcag
     6061 tgcgcgctca acgttaggga cgattactaa catcaatgcg ttatttcgtg tgttgttttc
     6121 atgttttgca acacctagtt taggatatgc aaatgcttat tcatttaatg atcctagtgg
     6181 aatgtgttct gtctgtcagg gaatcggtaa gacgattgca tttttaatag gattgcttta
     6241 tttttcggct attgataatg ctgattttgt attttctgat ccatttaccg cagaagtttt
     6301 gtctggaatt gaggaacagg caaagaatca tggttatttt gtattggtgc ataatgttaa
     6361 ttcagcagaa gatgttaaaa ctattcagag aaattggcgt tttgaggggt tcattgttgt
     6421 tggtgtacgt gtaaaagaat ttttggaatt aaataacgtt tttgatggtc ctgttgttta
     6481 tattgatacg catctttcaa aagagacatt aagagaactt gaacaacaaa tgaatcgttt
     6541 atttgtaaat acaaatgatt accaagctag tacattggca gtggaacatt tgattcatta
     6601 tggtcatgag aaaatagcgt ttctttcttt tgactacatt gtaggtgaac caagtgttat
     6661 tcaagaacga catcaagctt atatcgatac attaaagaaa tatcatttaa cctttaaatc
     6721 gcattggata tataacaact ctgaatttga gcgaatttat caagaattag ctgaatttac
     6781 tgcaattgtt gttactggag attatttagc ggctaaatta gtaaaatttt taaaaaataa
     6841 gaataaacga gtgatggaac aattatcgat tattggattt gatgatatta cttttgcaga
     6901 attaatggat cctgcgttga caacaatacg actaaatcca ggtaacaagg gggcgattgc
     6961 ttttcaccaa ctgattggac tggccaaaca agaagaaata aaaaatcaag tactactatt
     7021 agagggagaa ttgatttctc gagactctgt tcacaaaatc aaataaaaaa gctctgtgaa
     7081 ataagtatag ttaacaataa aatatccgaa cgatagagag aatgaactgt gatctagcag
     7141 ttcctcgtcg caaattcact agaattagca ttatttactc taaattgttc ggatattttt
     7201 tcttgttttt aattatgatt acagtgccta tttttaacga aatttgctta ttttcaaaat
     7261 gtatgattat atgttagtaa acactttcaa atatgaaaag aggagctatt atggtaggaa
     7321 ttagggatgt tgcaaaacgg gcgggtgtgt ccattgcaac agtatcgcgc gtgctaaatg
     7381 aggatccgac actttcagta accgatgaaa ccaaacgaaa gattgcagaa tcggttaatt
     7441 tttatcatta tgtcaaaaaa agtcccgttg caaaaaattt aacaaatatt gcattaataa
     7501 cgacagtttc tgaagtagat gagttggaag atccctattt tcgaacgatt cgcagaggga
     7561 ttcaagtcga agcagaacaa agcaaagtca atttgaagaa aattattcgt ttgtcagaaa
     7621 caccgttgga gcaagacgat ttgctaaaat gtcaaggtgt gttgattatt gggcaggtgc
     7681 tatcttctgt gattgaagaa gtatcagcaa ttaattcgaa tgtcgtagtg attgatgacc
     7741 ctagtattga agctgaagta gatgcagttt atactgattt aacaaaagca acgaatcagc
     7801 atttagatcg attgtataaa aaaggacacc gaaacattgc gtttatcgga ggaggacgtg
     7861 ttcgtttaga tagccaagga aataaacacg tgtcagatga tgattatcga aaaatagcct
     7921 atgagacgtg gatgaaacaa aaaggattag aaaaatatag tcaaatttat ttagaaggct
     7981 ggaccacact tgacggaatg caggcagcag atttactttt gaaaaaacat gctaaagata
     8041 agttgccgac tgctatcatg gtaggaaatg atcctattgc tgtgggggtt tatcgttcac
     8101 ttcaaaaaaa tggtctacat attccagaag atatttcgat tgtgagtttt gataatattg
     8161 aagttgctga atttttaaca cctgcattaa atacggtgaa tgtgaataca gaagaaattg
     8221 gaaaactagc agttcgcatg gttaatgaac gaataaaaga agttagaaat gtttcgatca
     8281 aagtgattgt ttctaataat attattgtta gagaaagtga aaaaaatatc gattaaaaaa
     8341 gtaaacatcc aaaaaagggt gtttactttt ttgtttacta atatttttag taaaaaatct
     8401 cgacaaaaca ttaagtaaac agttatggtg ttgttaacaa aaagaaaacg cattcaaaac
     8461 aggaggaatt aagatgaaac atttcaaaaa aatagcttta acagggatag ctgttttaac
     8521 tgggacatta ctcgcagcat gtggtggggg agatagtaat tctaaagacg ggcaagtaac
     8581 tttaagctat gcgagttgag atactgacca agctccagga ctaagaaaaa tgttagatga
     8641 atttgaaaaa caaaatcctg atatcaaagt agaaatggag acaacgcctt gggatcaata
     8701 ttgggttaaa ttagaagctg caacaacggg aggtaatatg ccagatgtag taaccatgca
     8761 ctctagcgaa tcctataaat atatgtcaca gaatgctttg atgggacttg atgatgttat
     8821 caaagaaaat gatattgaca tgggaaactt tactgaagga attgctgatt tctatacgct
     8881 tgaagacgaa ctatacgcaa tccctaaaga tgcttctgta gtggggctat ggtacaacaa
     8941 agaattattt gataatgcag gtgtcgatta tccagatgaa acatggacat gggaaacact
     9001 cagacaagct gcaattgatt taacagatga atcaaaaggc atctatggtt ttgcatcaca
     9061 tattggaaca gagactggct actggccatt tatttatcaa aatgggggag aagtatttgc
     9121 cgatgacaat acaaaatcag gtttgaatac cccagaagca caagaagctt tagcttttta
     9181 tcgagatatt gcacttgttg atcatgcttc accaacaatt acagaattac aagatcctga
     9241 taagttaagt cgttttcaat caggtagatt agcaatgatg attgaaggaa actggtttgc
     9301 accgggattt ttgaaaaatg actatctagt tgaaaatgtt gcttctgccg tgttacctaa
     9361 gggaaaagtt aatgcaacaa ttacaaatgg acttggttgg gctgccagtg cgagtacaaa
     9421 atacccagaa gaagtgaaaa aactaatggc atttttagct agtgaggacg ccaataaaat
     9481 ccaagcggaa acgggggcat caatcccagc actaaaaggc tttgaagacg agtgggctgc
     9541 ttcttcagat acaattgatt tgagtgcttt tggaaaaatg ttggagtatg gagtccctcg
     9601 tccatacaat aaagatggat tacgagctga acaagcagaa gttcaaatta ttaaccgtat
     9661 tctgtctggt gaagtaactg ttgaagatgg aaccgctcaa attgaaaaag aagtcaatgc
     9721 gatattgagc ggaaattaaa ttagttaatt atacaatata caggcgaaag gattctattt
     9781 cgtctgtata ttaatggatg aataccaaaa agggggatat tatgaaaaat cgaatttttg
     9841 gaaaatatcg taaagatcaa gtgatatggg gctatatttt tatttttcca acggcattag
     9901 gattaatttt attaaatata tggccagcaa ttcaaacagc aattttaagt tttcaaaaaa
     9961 cggtagggtt cggtgatact gaatgggtcg gattaagaaa ttaccaaaaa atgtttgcag
    10021 acggtgaagt ttttcagtct ttattaaaca cattaattta tgcagtggtt tcgataccta
    10081 gtattgttgt attatccttg ttggtggcag ttttaatgaa tagaaaagtt aaaggattgt
    10141 cgatttatcg gacaatttat tttctaccag tcgttgctgc accatccgca gtcgcaatga
    10201 tttggcgctg gatgttcaat aatgattatg gactgattaa taacatgttg gctaaaatag
    10261 gtctcgatgg accagcatgg ttaacggatc catcgattgc gatttattct attatcattg
    10321 taggagtttg gagtgctatt ggttataaca tggtgttatt actagccggc ttataagaaa
    10381 ttcctaaaga ttattatgaa gcagcggaaa ttgatggtgc tagtccaatc cagcagtttt
    10441 tcaacattac gttaccatta gttacaccaa cattattttt tgtagttgta acaacagtta
    10501 tcaatgcttt ccaagtattt gatgttattt ttatgatgat tactcctaat agtaccgcca
    10561 tgtttaaatc acaatcatta gcctatttat tctataaaca ttcatttatt ttaaatgaca
    10621 agggatatgg ttcggcaatc gttatgttcc ttttagtgat tatattaatt attactgcaa
    10681 ttcaaatgaa gttgcagaaa aagtgggtaa actattaagg aggctatcaa attatgaaaa
    10741 ataaattttt ttcaaatgcg ccaatccata tcatgcttat tttaggtggt attgcaatgg
    10801 cattaccttt tatttggatg attttaactt cagggaaaac gttggttgaa tctacccaaa
    10861 ttccacctac aattttccct gagaaatttc agctaagtaa ctatcaacaa gtacttgatt
    10921 tattaccatt catggctttt tatatcaata catttttaat ggttgttgga cgagtgattg
    10981 gctcggtttt attttcagca atggctgcat atgcttgtgc gcgtctaagt tttccaggga
    11041 aaaatatcct tttcagctta gtacttattc aaatgatgat tcccggttcc atttttatta
    11101 ctccacagta tttattagca caaaaattgg gtattttaaa tacaattcca gcattaatat
    11161 taccaggggt agttagtgcg tttggtacgt ttttattaag acaatttttc ttaggtttac
    11221 ctgatgaatt ggaggaagcg gcctatttag aaggtgccaa tatttggacg atctttttca
    11281 aaattatgtt gccgcttgct aaatcaggat tggttgcact tggaatattc acagcgttgt
    11341 ttgcatttaa agatttaatg tggccattga ttgtcaatac ttcaattgat aagatgcctt
    11401 tagctccggg attagcaaac ttacaaggac aatatgccac gaacttccca caattaatgg
    11461 caggttcgtt attagcaatt tggccaatag ttgtgatatt catcgttttc caaagaaaat
    11521 tcattgaagg aattgctaca acaggtagta aattataaaa ctattaatta gtgattggag
    11581 agtaagtaca tgacaaaaat tacatttatt ggtgcaggaa gtactatttt tgcaaaaaac
    11641 gtattaggcg atgcgatgtt aactccaagt ctacaagatg cacatattgc attgtacgat
    11701 attgatgaaa aacgactaaa agaatcaaat ttaatgctta aaaatattaa taaaaattcg
    11761 aatgaaaatc gtgctgatat tgtttcttat tatgatcgca aagaagcgtt aagagaggct
    11821 gattttgtta tcaatgctat tcaagtgggt ggttataaac cttcaacagt gattgatttt
    11881 gatattccta aaaaatatgg gttgcgacaa actattggtg acaccatggg gattggtggg
    11941 atttttagaa ccctacggac actaccagta atgttagact ttgctaaaga aatggaagaa
    12001 gtttgtccaa atgcttggtt attgaactat acaaatccga tggcgatgtt aaccatgggt
    12061 gttttaaaag cgacgagtat taagactgtt ggtttatgtc atagcgttca agtatgcgta
    12121 ccagaattgt ttgagcattt aggaatagcc gatcaatatg acttaaatga ctttcaatgg
    12181 aaaattgcag gcattaatca tatggcattc ttgttggaaa ttacaaaaaa tggggaagat
    12241 ttctatccaa caattcgtca gttagctgca gaaaaaccaa atccacatcc agattctgta
    12301 cgttttgaat tgttgaaacg ttttggttac tatattacag aatcaagtga acacaatgca
    12361 gaataccatc catactttat taaatcaaaa tacccagaat tgattgacga attagggatt
    12421 ccgttggatg aatacttacg tcgttgtgaa caacaaatta atgattggga aagcatgcga
    12481 gaggacattg taaataatgg ggagttaaca catacgagaa gccgtgaata tgcttcatat
    12541 atcatggatt ctattacgac aggaactccg tcagtgattg caggaaatgt cttaaataaa
    12601 ggcttaatca caaacttacc gacagatgtt tgtgtggaag taccttgttt agtcgataaa
    12661 aatggcgtgc aaccaaccta tgtcggtgaa ttgccaacac aattagctgc tttaaatcgg
    12721 acgaatatca atgttcaaga actgacagta gaagccgctt taacactaga taaatcaaaa
    12781 atttatcaag cagcgtattt agatccacat ctatcatctg aattgtcttt aacagatatc
    12841 aaaaatttag tggatgattt aatcgaagca catggggact atttacctga atataattaa
    12901 aaagaagctg aaagagtaag gaattttcaa ttccttactc ttttcttagt taaatttagt
    12961 aaaaatattg acaaaacact tagtaaacag ttacattagt gttaacaaaa agaaaacgca
    13021 ttcaaattgt ataaggagga gcataaaatg aagtggtcta aaaaaattat tttagcttgt
    13081 atagcactag gagcaacgat ctctttgact gcttgtggaa aaaatcagga agatgcaagc
    13141 ggtaaggtag aaatagagtt ttttaatcaa aaaaaagaaa tgactcaaac gattcaggag
    13201 attgctaaag attttgaagc aaaaaaccct gatattcatg taaaagttgt ggatgtaccg
    13261 aatgctggtg aagtaattaa aacacgtatg cttgcaggcg atgtaccaga tgtcattaat
    13321 ctttatcctc aaagtataga attgaaagaa tgggcgaaag ctggttattt agaggactta
    13381 accgaagaac cgtatttaga gaatatcaaa aatggatatg cacaacgttt tgctattgag
    13441 gatcgtgtat atagcatacc attaaccgct aatgtctatg gtttttacta taacaaaact
    13501 gcttttgagg aaatggggat tcaagcacca gaaacttggg cagaatttga aaaaatagta
    13561 gctgagatta aagatcaaaa caaagtaccg tttgcgattg caggagcaga aggctggact
    13621 ttaaatggtt atcaccaact agctatagcg actgctgctg gtggtgaaga ggaagcgaac
    13681 aatgtttggc gtttctcaga agttaatgga attaatgctg aaagcaaaga aatgcaaaaa
    13741 gattttaatc gattagattt gttaagagaa ccaaaagctt tgcaaaacaa ctggcaaggt
    13801 gccggttata acgatacagt agttactttt acaaaaggtg atgcgttgat tatgccgaat
    13861 ggttcatggg caatgccgat gattcattca caaaatccag attttgaagt aggaactttt
    13921 ccttttccag cagatgaagc aggtcaaagt ctaacgattg gcgcaggaga cctagcctta
    13981 tcagtttctg caacttctca acataaagaa gaagccaaac gttttgtaga atatatgaca
    14041 acacctgaag cgatgcagaa atattatgat gtagatggtg caccgtgtgc tgttgagggc
    14101 gttatcgaga atactcagga ttcaccatta agtggtttaa ctgaacttgc ttttactgat
    14161 cgtcatttag tttggttagc caaagattgg aatagtgaaa atgattttta taccttaaca
    14221 acaaattatt tacacaatgg caatcaaaaa gccatgatta acgcattaaa tgctttcttt
    14281 aatccaatga aagctgacgg aaggtaggaa aataaaatga aaataaaaga aattttaaat
    14341 cgttactggg caatcatttt tgtagcaatt ccaattattt tgcagatgat ttttttctac
    14401 tttccaatgg ttcaaggtgc tttttacagt ttaactaatt ggactggtct gacttataat
    14461 tttgattttg tgggtttgaa caattataag attctttttt ctgatccgaa gtttatcaaa
    14521 tcgattggct tcactttaat tgtgacgctt tgcatgattg ctggacaaat tggttttggt
    14581 attttgattg cgcgggcgtt gaacgcaaat attaaaggga aaacattctt tagagcatgg
    14641 ttcttttttc cagcggtctt atcgggcgtg gttgtttctt tagtatttaa acaaattttt
    14701 aactatggtt taccaaaaat tggtagtatg ttaggcattg aatttttaca aaccagtctt
    14761 ttaggaacaa catggggagc gatttttgca gtaatttttg ttttactttg gcaaggaatt
    14821 gccatgccag tcatcatttt cttagcgggt tttcaaagta ttccacaaga aattattgaa
    14881 gctgctagaa tggatggggc gaatgataag caaatttttt ggaatattga aatcacctac
    14941 ttattaccaa gtatttcaat ggtatttatt atggcattaa aaggtggctt aacagcattt
    15001 gatcaaattt ttgctttaac tggtggtgga ccaagcgatg ccacaacatc tttggggtta
    15061 cttgtttata attatgcttt taaaaacaat cagtttggtt atgcgaatgc tattgcttta
    15121 gtcttattta tcttaattgg gattgtttca ctggcacaat taaaattatc gaaaaaattt
    15181 gaaatctagg aggtttccca atgaaaacat caaaagaaaa aaatatttct aaatacttgc
    15241 ttttattatt agggggcttc atgattttag ttcccttagt ttcaacgcta ttcggttcat
    15301 ttaaaacaac acccgatatt atgaataatt tctttcgttt tcctaatcca gcgactttgg
    15361 aaaatttccg aagattgtta gcggatggaa ttggtcatta cttttggaat tcggcaatca
    15421 tcacaatcat tgcagtagtt gctgtgacag caattattcc tatggctgct tattcactag
    15481 caagaaaaat gactcgtggg aaagcatacg gattgatgta tttattttta attttaggaa
    15541 tttttgttcc tttccaagta attatgattc cgattaccgt tatgatgagt aaaattggtt
    15601 tagcaaatat gtggggatta atcttactct atctcactta tgccgtacca cagacactat
    15661 ttttatatgt tggttttatt aaactaaatg tgcctatcag tctggatgag gctgctgaaa
    15721 ttgatggggc tagtcacttt acaacttatt tcaaaattgt tttcccaatg ttaaaaccaa
    15781 tgcatgcgac gactattatt cttaatgctc tatggttttg gaatgatttc atgctaccat
    15841 tattaatttt aaatcgtgat tctaatatgt ggacactacc attgtttcaa tataattata
    15901 cgggacaata ttttaacgac tatggtccaa gttttgcttc ctatacagta ggaattgtca
    15961 cgattacact agtttatctt gctttccaaa gaagtattat agctggaatg agcaatggag
    16021 cagtgaaata accaataaat tattctcatt ataaaggagt tcataaactt atgattatat
    16081 ttgacaatca cacacaaaca tttcatttac aaaataaaaa aattagctat ctattaggaa
    16141 tcgaagaaaa taattattta acgcatcttt attttggaaa aaagattacg cactattctg
    16201 gtgggtatcg ctacccccga acagatcgtt ccttctcacc caacaatgca aatgcgcaag
    16261 atcgtttatt atctttagac acattaccat tagaatttcc aggatatgga catggtgatt
    16321 ttagagaacc ggcgcataat attaaattag gaaacggtag tcgtgtaaat gattttcgtt
    16381 atgatagcta cgaaattcaa aaaggaaagc ccagcttagc gggattgcca gccttatata
    16441 cggaagatga tgatgaagct gaaacgctga ttattcaatt gaaagacgcg attagtggat
    16501 tgactttaca gttgttctac acaatttatc aaaatcacag tgtaattatt cgttctacgc
    16561 aattagtaaa taatagtgat gaaacagtgg agattaaccg cttagctagt caatcaattg
    16621 attttccaaa tcgtccactc gagttaattc atttaaatgg tacctgggca agagaacgtc
    16681 aaatgactag agaaaaaatt catacaggga taaaagtatt agatagtaaa cgcggatcaa
    16741 gcagccatca acaaaatccg tttgttgctt tagtagatgc caaaacagat gaatttcaag
    16801 gagaggcata tggatttaat ttagtttata gcggtaatca cgaaacggtg attcaaaaag
    16861 atccatttga ccaaacacgg gtcattatgg gaattaattc atttaatttt ggttggcaac
    16921 taaaaactgg cgactcattt caaacgccag aagtcgtgat ggtttatagt aatgaaggtc
    16981 tgaatacgtt atcacagacg tatcatgaat tgtataatca ccgtttaatt cgtggaaact
    17041 atcgtttaaa agaacgtccc acgttaatca acaactggga agcaacgtat tttgatttta
    17101 acgaagaaaa aatcatgaat attgtcgatg atgcgaagaa cttgggcatt gaaatgtttg
    17161 ttttagatga tggttggttt ggcggtcgtg aaaatgactt cacttcatta ggtgattggg
    17221 ttgaaacaga aggcaaactt gcttgtggtt tggaaaattt agccaagcaa gtgcatgata
    17281 acgggatgaa atttgggatt tggtttgaac cggaaatgat ttctgaagat agtgaactat
    17341 ttcgagcaca tccagattgg gcattgggta ttccaggtcg tgaccgctca attagtcgaa
    17401 atcaatatgt tcttgatttt tcaagacaag atgttcgtga taatatctat caacaaatga
    17461 cggcgatttt tgatcgtgta ccgattgatt atgtgaagtg ggatatgaat cgaaatatga
    17521 cagaagtcta ttctgtcttg ttggactcaa cgatgcaagg tgaagtggct catcgttata
    17581 tgttagggtt atatgaattt ttagaaaagt taacaacgaa ttatccaact attttatttg
    17641 aaagttgttc gggtggaggc ggtcgttttg atgcaggttt cttgtattac atgccacaaa
    17701 cttggacgag cgacaatacc gatgccgtgg ctcgtctgaa aattcaatat ggaaccagct
    17761 tagtgtatcc aatttcaagt atgggtgcgc atgtttcagc agtcccaaat catcaaacag
    17821 gaagagaaac gagtttaact attcgtggca atgctgcgat ggctggtgtt tttggttatg
    17881 agctagatct aacgcaatta acttctgaag aaaaagcaga aattaaagaa caagttgcct
    17941 tttataaaaa gcatcgccaa cttttgcaat atggaacttt ttatcgcttg gaaagtccgt
    18001 ttgaaggcaa tgatactgca tggatgtttg tctcaaaaga ccaaacagaa gccatggtct
    18061 tttatttccg agtattagca gaagctgcgc atccattagt cacattgaaa ttagcaggat
    18121 tagcagaaga agcaacttat caaatggaag atgtaacatt tgctggcgat gaattgatga
    18181 atctcggttt ttatattgac tcagaactac atggtgatta tgcgacacaa cgcttttatt
    18241 tgaaacagat atagtagctt gaatttacaa tataagtgca acaccaaaag agactcattc
    18301 caaacgaaga aaatatgttt tatttacacg catttactaa aaagcagcct gatttgaatt
    18361 gggaaaatga agaagtacgt gaagaaatct atgcaatgat taactattgg ttagataaag
    18421 gactaggcgg atttagaatc gatgcgatat taaacatcaa aaaaaaacta gagtatggca
    18481 tctttgaatc tgatggagaa gatgggttag ccttcattgg gccctggatt cttaatcagt
    18541 cgggcattga agtgtggtta aaagaaatga gagagcggac atttaaacca cataatagta
    18601 tgacggtagc agaagccgat gttcctaatg aacgtttaga tgaatatatt ggtgaagatg
    18661 gctattattc gatggttttt gattttagtt atacggatat tgatgtacct gaaactggtg
    18721 aatggtttaa agatagccaa tggacatgga cggatatgcg taccaatatt tttacgaatc
    18781 aattagttac gcaagataaa ggttggggcg ccttatattt agaaaaccac gatcaaccac
    18841 gttcaattaa taaatatatt ccagaagaat ggatcaatga ttatagtaaa aaaatgttgg
    18901 cgacgctttt tatgttacta agaggtaccc cttttattta tcaaggacaa gaactaggaa
    18961 tgaccaacat agaaatggca tcattagaag attttgatga tgtagctacg cattctcagt
    19021 ataaacgggc attagaatat ggattggcac cagagcaagc attgaaagct gtcaataaac
    19081 gaagtcggga taattctcgc acacctatgc aatggaatac gcaaaaaaat gccagattct
    19141 caacttctga taatgtatgg ttaaaagtaa atcctaatta tccagaactc aatgcagaag
    19201 ctcagttaac caatcaacag tcggtattca attattatca tcaattaatt aaattaagaa
    19261 aaaatagtgt atacaaagac gtgctaatct acggacaatt tctaccagtg aaagataaaa
    19321 atgaacatat tttgctttat gaacgccaat tagaagataa aatcgtatta gttatcttaa
    19381 acgttacagc aacagaacaa gaatattatg tagatgaaca gtaccaacaa gtattaatca
    19441 ataattatga agatgtttta ttagatcaaa gtcgaaaatt gcgtttacga ccgtttgaaa
    19501 gtattgtatt agctaattat ggaggacaat tatgaaaatt aaaaacgaag caatgctcat
    19561 cacctatgca gatagtttag gaaaaaacat gggcgaatta aaacaagtct tagacaaaca
    19621 tttacaaggt gttattggtg gtgtacatct gttgcctttt tttccatcga caggtgatcg
    19681 aggctttgcg ccgagtgatt atacgacagt tgatccagct cttggaacat gggaagatgt
    19741 ggaagcatta ggtgaagatt attatttgat gtttgatttt atgattaatc acatttctcg
    19801 tgaatcaaaa tttttccaag atttcaaaaa aaaccatgag cagtcaccat acaaagaaat
    19861 gtttatccgt attcatgaat ttttcccaga aaatcgacca acacaagaag atattgattt
    19921 aatctacaag cgtaaagaca aagcgccgtt tcaaacggta gaatttgcgg atggtacgac
    19981 agaagaggtt tggaatacct ttggggaaga acaaattgat ttagatgtga ccaaagaagt
    20041 tgtgaaagaa tttattcgag aaaccatcaa agatatggcg aaccatggct gttctttaat
    20101 tcgattagat gcgtttgctt atgcgattaa aaaattagat accaatgatt tcttcgtgga
    20161 accagatatt tgggaacttt tagacgaagt gcgtcaagaa gcagcgaaat atgacgtcga
    20221 attattacca gaaatccatg agcattattc cattcaaatg aaaattgcca atcatgatta
    20281 ttatatctat gacttcgcct tgccaatggt cactctgtat tcactttata gtggaaaatc
    20341 agaacgttta gccaattggt tgaaaatgag tccgatgaag cagtttacaa cattggatac
    20401 gcatgatgga attggtgttg tggacgctcg tgatttatta acagatgaag aattggatta
    20461 cacctctgag gaattgtata aagtcggggc gaatgtgaag aaggtctatt caagtgccaa
    20521 ttacaataat ttagatattt atcaaattaa cagcacctat tatagtgcat taggcgataa
    20581 tgaccgtagc tatctgttag cacgtgcgat tcaagtattt gcgccaggga ttccacaaat
    20641 ttattacgtt gggttattag caggaaaaaa tgatattgaa ctgttggaag caacgaaaga
    20701 agggcgtaat attaatcgtc attactatga tttagccgaa attgaagaag aagtgcaacg
    20761 gccagtgatt caacaattat ttgcactttt aaaatttaga aatgaatctg cggcgtttga
    20821 tttggatgga acgattgaag tagcaacgcc atcagaatca gaaatagtga ttacacgtaa
    20881 aaataaaaac ggtagtgata gtgcaacatt aacggctaac ttggatacga aagaatttat
    20941 cattgagtct aaagatataa aaattttcac tagtgttgca ttaaaatttt aacctattcc
    21001 atagaacaaa aaatccttta tactagcact tggatgactt atccaagacc aataaaaagg
    21061 actcatacat ggataagtat aaaacaaata cagcatttaa taaatggttt tctgccataa
    21121 aattaggaaa actttctgtc aactcccaaa aatgtatttt tgattacaat tcgtatcgta
    21181 aaaaactgtc ttttgaagct gtgctcaagc tctttctcta cgcagttaat gaagaaaaag
    21241 aaagtttgcg tgatttgagt acagctctta tcgaccgatc gctccaacta gaaaccgatg
    21301 tgtcatcgat tagtcatacc caattgtctc gagcatttaa tgcacttgaa cctaaagtgt
    21361 tagaagaaat ttttcaacaa ctgttagaaa aagttcaaca tcaaatcaaa ccaaccaagc
    21421 gaaatcatct gtatctgatt gattccagta cgttttcgct tagtttaaaa cgtcataagt
    21481 gggcgacttt ccgtcaaaca aaatcaggtg tcaagttaca cttaaactat tgttatatgg
    21541 acgatactac gatgtatcca actgatttta ccttaacaaa tgcccatgaa catgatctca
    21601 atcaactacc agtattggtg aatcaaccag aggcaactta cgtgtttgat cgtgggtatt
    21661 aggactttga aaagatggat cagatgcatt gggatggcta tttcttcgtc actcggatta
    21721 aaaaaaacac caaagttcac gtgatagata ctctggaaac atcgccagaa acagaaattc
    21781 tacgagacga gctggttcgt ttaggatcta aaacctatct aaccgccaat ttccgactag
    21841 tcactgttca agataagaac ggacgtgtgt ttcaatttat caccaatcga atggacgtct
    21901 cttcaaaaga aatctctgat atgtatcacg ctcgttggca aatcgaattg tttttcaagc
    21961 acatcaaaca acacatgacc attaaaacct tcttttctca aagtgaaaaa ggcgtgcaga
    22021 atcaattgat tttaacgatg atttccgctc tcctcacgtt tctcatcaaa ttggagacga
    22081 aaacggaaaa atcagtgttc caaatcaaac gattctttcg ttatttactg tttcagccct
    22141 ttgaatgttg tctagaaaaa ttaattccca catgagaaaa aagaaatttg gctcgttact
    22201 tttggttttc agttgaataa cagataaaaa attttctgga aaaagtcatc ctctgcgtca
    22261 gcacagtttt ttttgactta ttttcagagg aaatagtttt cagaatattc taaaatgttt
    22321 tatgcaacac tagtgatatt ttttagaatt agatttctaa tgtgcatttt ttgagtatta
    22381 aggagcaagt atacaaagat ttataaagct gattaaattt gaataaaaat atgcaggaac
    22441 gctactattt ttagtagtgt tcttttttat atttgaataa aaaatgtggt ggttaaatgg
    22501 tggttataac aaaaaatgaa ttaatgaaat taggttatgg gaagtatcag tctgagagaa
    22561 tcatacgaca ggcaaaagca attatggttt caaaaagcta tacctattac gaaaatagaa
    22621 gattaggact agtacctgtt gaatctgtag aagaagtttt aggtatgaag atagaggtag
    22681 aggaggattt tcagaatcat ggttaatttt aaaaaagata aaaatgggaa atatcatttt
    22741 actgctagtt tgggattcga caaacgaaca gggaaaagag tacaaaaaaa cgtagagggg
    22801 ttaaaacagt taaagaagaa aaaaagcgta taccgaactt gtttctaatt atggaaaaga
    22861 agcagaaact tctcaaagta ctatgttgtt tgaggagttt ttttataaat tattcctacc
    22921 ttattatcaa gggaaagtag aagaaagaac atataaaaat cggttatcta caatcaaaaa
    22981 aacttttctt atttctttaa aatggagtta agagaaatac gtccaattga cattcaaaag
    23041 tggcaaaata atttattgag caaatataaa aattcttatg taagaaacat gtatgggatt
    23101 tttcagatgt cattagatcg agcagttgtt ttgggactac ttgaaaaaaa tcctgcaaaa
    23161 gttattggaa atgtgaagaa aaggaaaact acagttgatt tttggacaaa agaagaattt
    23221 acaaaagtta tttcaacttt ttatattgat gatttgtacc aacattttgg ttttatttgt
    23281 atgtggttac tttttatgac cgttatgcgt ttgggagaag ccactgcatt aacttggaaa
    23341 gatattgatt ttgaaaataa aaacttgcgt gtgaataaaa cactctatta taagagagcc
    23401 aaaacctatg agtttgtaga acccgaaacg gcttctagta ttcgtacaat cgaactagac
    23461 gacaatacaa ttaccttttt aaaagcttgg aaggagcgtc aagtttcaat aggaggcatg
    23521 tcgtttgtac tttcttataa tggaacacct actcagaaat atacaatccg tcatattatg
    23581 agaagacatg caacgatcgt tggtgttcat ataatccgca tacacggatt aaggcatagt
    23641 catgcttctt tgcttatatc acaataaaaa gatgcacttc gaattaaaga aaggttaaaa
    23701 catgctgatg tacaaacgac tttaggaact tatggtcatt tgtatctaaa ttcattgaga
    23761 gagataacaa atgatcccac agattatatc caaactaatt tttctaaaat caaaccgaca
    23821 cctatttacg ataataaaaa ataaatgata aacaaaagta ggatcacacc aaaagaaaca
    23881 cactagaaaa actataatac aggcttttct agcgtgttgt ttcttatttc cgcctattta
    23941 tacattatac tcataaagca tttaatgcat cgatcgtagc cgcattgtct atatgggtat
    24001 ataaagttgt tgtattggta cttgaatgtc ccaattgttg ggcagttaat accaatgaat
    24061 ttgtctgttg gtagagtcta gtagctaatg tatgacgcag tttgtgaggg ctgacttgaa
    24121 ttctaaagcc ttttgaatat tttgctacca tccgttcgat tgcaataccg gatatacgct
    24181 tggcttctcc ttggtaaatt gctagaaata aagctttttc gttttctgtt actttatatc
    24241 gttctttccg aatagctaga taattagcta aatattccat tgcgaatgct gctatattga
    24301 cagcatctct tttatttcct tttctagtta ctaccacatt attcttatct aaagataggt
    24361 catctaaatt aatatttata acctcggaga gtctcaatcc agatcctaaa atcagtgcat
    24421 tgatcgccag gtctctttct acatctcgtt gataatagat caaagctcgt ttactcaaag
    24481 tatttttata ttcattggca atataatcta gataattttg tgtatcctta tctagaaata
    24541 attttttctc aatggcattg gcacgtgcag ctaacgtagt tttatctgtg atggttgcta
    24601 cttgatccat aggattattg tctaagtatg gttttcctag aggattattg gaacttttcg
    24661 aaagatattt aaatagaacc tttaatgccg tgatatttct attgatagta gaagtagata
    24721 gacctaagtt attattatct ttgagcttag tttttgttgt ctcttttttt acattttctt
    24781 ttgtgcgacg tttcaaatga gatttgtaca agtttaggtc ataggcagtt aactgtctta
    24841 tcgaggtgat agaagtatca ggaacgatag actcactcag aagccattca taaaagagct
    24901 tataattttt tagatattct aaagtggttc gaggtgattg atctttatcc tcacgatctt
    24961 gaacaaaatc ttttatataa tcgggcatat gaagtatgat tgtatctatt ttttgatata
    25021 tttctgtatt tttcatgtca ttcatccttt caataagtag gggagaagag tatctctata
    25081 attggactat accaattata gaatgttttg tcaattggta tgctctaaaa tttattaatt
    25141 tgtttcaaaa aaagcatata aacaggtata cgtttaataa tttaaaataa atggtataca
    25201 taaataggga aggaaataga agggagcaat ctaaattttt tgaattttct taattaatta
    25261 tatagaaaga acaatctttc tatagagtta gacatgagag ggactatgct tgatttaaaa
    25321 tcaacaagcg tatatactgt atatacaaag aaaaaggagg gagaagacta tggcaattaa
    25381 agaaagaaaa tttagggaag tggggaactc agtagtatta actatttcaa aggagtttct
    25441 taaagaaaat gggttaaatc ccggagatac ggttttttta gatgaagaaa aacttcgagc
    25501 ggcaattaca aaaaaacaag ccttatctga tgaaattgat ttagcaatat ctcaagcatt
    25561 aactgaatat gatactactt ttagagagct tgtcgataaa tgagtattca ttacctagaa
    25621 gccaaagata ttataaaaat gaatgtaatc caaataaaaa aatactctcc taatgaaccc
    25681 cttggtgtaa aggatgcgaa tgctttagaa atgtgtgtag ggcaacttcg agcctcagct
    25741 tttggtgaag aggtttatcc ttcgatttat gaaaaagcag ctatcctact tatacaattg
    25801 ataaagaaac atccttttca caatgcaaat aaacgtactg ctttcttagc tacttttgtc
    25861 tttttgaaaa tcaatggaca gcttttagct attgatcaaa aagatgctgt aaatttagcg
    25921 gtatatattg ctacgtatga taaggatttc gatcaactaa aatatgaagt gatcaacact
    25981 ataaagacac atacgcagcc catttaagga gttactgtat gtgtctttat agggttatta
    26041 gctgctatag cgaaataatt gaagtaaatt acaaatagct ataattcaaa tccaactata
    26101 tagaaaacgt aaattttcta tatacttgga tatgctggaa tgtttaagag aataattaca
    26161 tttctagaaa atacaataaa aattacagga taattagcca tatcctacct cctctagcag
    26221 ttgctcaaaa gttagcacta agtaacttct tttttgttgc tggtaacaat ttatcaatac
    26281 taaaatagcg tttaagtatc taataaatac taattttaaa gctcttaatt attatgaaac
    26341 acgatataac aatattgcta tatcgtgcta ttgtaatatt atacatttga agacagcgta
    26401 ttcttgttct aatatcagga attttttata aatatcagtc atattaagac tcaaaattta
    26461 ttggtatgtt cctctgtata gagtttgacc gtctaccatt atatagcaat tattatcatt
    26521 gttgtcttgc accaatatac cgttaagggt agcactagga gtagtaacaa tcactggaaa
    26581 ctcatgagaa agctcggtca tttttcctgt tctgctagaa tcgtgttcta ttgtcaagcc
    26641 atttactata aacgtgaata ctttacttcc tattgttata gtagcttttt gagaaacagt
    26701 ttctgtagct ggagctgtgc ttctttccga atttgttagg gtttcactgg attcattgct
    26761 ataaacaatt gtagaggatt ctacggcttc ttgagtgtcc acgttggtgc tgctagcttc
    26821 atctagcttc cttttgtatt gttcgttact gattgctaag ctttcccgtt ggtcatcaag
    26881 cttattcatt tctgtaatgg tataaaataa tcctcctgct agtgctatat taacaactaa
    26941 actaaccgca aataatacct ttttcattct tccttctctt ctttctcttt ttgtaattcc
    27001 ttacttttgg ataggctaca attaactaga cagaaaaat
//
LOCUS       DAKCAA010000036        26734 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000036 DAKCAA010000000
VERSION     DAKCAA010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.036"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(20..967)
                     /locus_tag="OUE31_001651"
     CDS             complement(20..967)
                     /locus_tag="OUE31_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0222662.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(1096..1860)
                     /locus_tag="OUE31_001652"
     CDS             complement(1096..1860)
                     /locus_tag="OUE31_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCU0222663.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(1864..2253)
                     /locus_tag="OUE31_001653"
     CDS             complement(1864..2253)
                     /locus_tag="OUE31_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222664.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            2388..2930
                     /locus_tag="OUE31_001654"
     CDS             2388..2930
                     /locus_tag="OUE31_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HCU0222665.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            3078..3710
                     /locus_tag="OUE31_001655"
     CDS             3078..3710
                     /locus_tag="OUE31_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222666.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(3844..3969)
                     /locus_tag="OUE31_001656"
     CDS             complement(3844..3969)
                     /locus_tag="OUE31_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0222667.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(4103..4996)
                     /locus_tag="OUE31_001657"
     CDS             complement(4103..4996)
                     /locus_tag="OUE31_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HCU0222668.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(5178..6104)
                     /locus_tag="OUE31_001658"
     CDS             complement(5178..6104)
                     /locus_tag="OUE31_001658"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HCU0222669.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(6189..6950)
                     /gene="pflA"
                     /locus_tag="OUE31_001659"
     CDS             complement(6189..6950)
                     /gene="pflA"
                     /locus_tag="OUE31_001659"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HCU0222670.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(7194..9425)
                     /gene="pflB"
                     /locus_tag="OUE31_001660"
     CDS             complement(7194..9425)
                     /gene="pflB"
                     /locus_tag="OUE31_001660"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCU0222671.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(9702..12152)
                     /gene="parC"
                     /locus_tag="OUE31_001661"
     CDS             complement(9702..12152)
                     /gene="parC"
                     /locus_tag="OUE31_001661"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HCU0222672.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(12164..14209)
                     /gene="parE"
                     /locus_tag="OUE31_001662"
     CDS             complement(12164..14209)
                     /gene="parE"
                     /locus_tag="OUE31_001662"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HCU0222673.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(14375..14809)
                     /locus_tag="OUE31_001663"
     CDS             complement(14375..14809)
                     /locus_tag="OUE31_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HCU0222674.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            14936..15574
                     /gene="plsY"
                     /locus_tag="OUE31_001664"
     CDS             14936..15574
                     /gene="plsY"
                     /locus_tag="OUE31_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HCU0222675.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(15706..16581)
                     /locus_tag="OUE31_001665"
     CDS             complement(15706..16581)
                     /locus_tag="OUE31_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCU0222676.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(16663..17454)
                     /gene="codY"
                     /locus_tag="OUE31_001666"
     CDS             complement(16663..17454)
                     /gene="codY"
                     /locus_tag="OUE31_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HCU0222677.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(17472..18872)
                     /gene="hslU"
                     /locus_tag="OUE31_001667"
     CDS             complement(17472..18872)
                     /gene="hslU"
                     /locus_tag="OUE31_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HCU0222678.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(18886..19434)
                     /gene="hslV"
                     /locus_tag="OUE31_001668"
     CDS             complement(18886..19434)
                     /gene="hslV"
                     /locus_tag="OUE31_001668"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HCU0222679.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(19471..20376)
                     /gene="xerC"
                     /locus_tag="OUE31_001669"
     CDS             complement(19471..20376)
                     /gene="xerC"
                     /locus_tag="OUE31_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HCU0222680.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(20574..21950)
                     /gene="trmFO"
                     /locus_tag="OUE31_001670"
     CDS             complement(20574..21950)
                     /gene="trmFO"
                     /locus_tag="OUE31_001670"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HCU0222681.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(21919..23997)
                     /gene="topA"
                     /locus_tag="OUE31_001671"
     CDS             complement(21919..23997)
                     /gene="topA"
                     /locus_tag="OUE31_001671"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HCU0222682.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHGHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(24119..24976)
                     /gene="dprA"
                     /locus_tag="OUE31_001672"
     CDS             complement(24119..24976)
                     /gene="dprA"
                     /locus_tag="OUE31_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HCU0222683.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(25032..25799)
                     /locus_tag="OUE31_001673"
     CDS             complement(25032..25799)
                     /locus_tag="OUE31_001673"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HCU0222684.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(25792..26652)
                     /gene="ylqF"
                     /locus_tag="OUE31_001674"
     CDS             complement(25792..26652)
                     /gene="ylqF"
                     /locus_tag="OUE31_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HCU0222685.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
BASE COUNT         7098 a         5735 c         4577 g         9324 t
ORIGIN      
        1 atatatatag taataagact taattcgttg tctctctgat aactagttca ggaaaaaaac
       61 gacgataacc ttgactcgcc cctttttctt ctattttttt taacaacatt tctccacata
      121 cttcacccat acgtataata tcttgcttga tcgttgtcaa tttaggtgaa ctgatttggt
      181 ctaaaaatac cccatcaaat ccaatcacac caaattcttc gggcaagtgt cctccagcat
      241 ttataatccc tcttactgct cctagtgcta gccgatctga actacataca aaacaagttt
      301 tatctgtaaa atctgcccag ttttctgtca tatatctttc tacttctgtc gaatgatttg
      361 gaaaccgcaa gattttacta ggaagatcaa cttccttcat cacagataaa taaccagttt
      421 cccttgaaat ttcaaaaggc tcgtccactt cgataccgat ataaataatc gtttgataat
      481 ctctttctaa ggcatattgc gttgcttttg ctgtaccata ttcattatcg ctgtctacat
      541 aatcatatcc ttcagaattt tccccaaaca agacaactgg tttttccaaa cggtcgatcc
      601 aatcgaagtc tttttttctg acacctgtga tgatgtatcc atcacaagaa ccgacgtcga
      661 aggcatcatt tgtaactaat tggagagaat aatgcgcttt accgatccgt ttagcgattc
      721 ccatcagcaa attcatgtaa tagggctcag ttgtgtcgat ttcttccagt ataaataatt
      781 tgatgatctg cgaccgattc gtgacaagtg cttttgcagc aatatttgga cggtaatcca
      841 gttcagccat tgctgagaaa actaactctt tcaattcgtc agtcacctgt tccggatgat
      901 tgatgactcg agagaccgtc atttttgaaa cattggcacg ttttgcaaca tctgctaaag
      961 tgggcatgct ctcttccttt ctaacatgtt gtcattctta ctatcaatta taccaaattt
     1021 tcctaacaga gtttattata gcccaaaata aaaaacggaa aatcctctat cgtcatgagt
     1081 gattttccgt ttcaattatt tatacttttt tatcaaattt tttgctaaaa aagtggaagc
     1141 ttcttccatt agtggtattt gtaccatatg tcgctgtgtt tttgaggaac gaaaaacaat
     1201 ttcttttccg taagacttat gccgattttt ttctacaaat cgttccgttt gtatataagg
     1261 gattttttcg tcagcttgtc catgccaaaa gaacagagga cgtccagcta acttttccgg
     1321 ctgcaatgac aaatcatagc tcttaaccca tgaaatcaaa tcaaaatagt cttttggtac
     1381 gacataatta tattccgatg cgcgccttac gatttctttt ccatattcca aaggtgcagg
     1441 ggaacccatc aaacacacgc ccgctactat atgaggatgt ttagccaaca aggcgcatgt
     1501 tgtcattccc cccatcgaaa ccccgccaac tgcaagctga tcatgtagaa gacctctttt
     1561 ttctaaatgc ttgataagtg tgtcaaattc aaacagattt ccgtagatac tatcccaaaa
     1621 tgtataggat ggaatagaag aaaccggctg tttgcgctcc ccatgattca tcgcatctgg
     1681 caggatcaca cgaatgccct gctgcgcaat ttttcttcct tgcgtcaaaa ctaactcctt
     1741 acttgtctgc catccgtgat aatagatgac aacgggaata cgttcctctc ttaattcttt
     1801 cagaacaact tctaacactg gaatatgatg gacagaacgt ttcaatataa ttggattcaa
     1861 ttgttactca cctattttca ttaaatttcc tgatcgccat agcaaccatg ctccaacagt
     1921 tgtctggaac aggttcagtg taccaaataa tataaatgca ggactgaatg gctcgggaaa
     1981 taagcacaga gaacaaagtc ccaccactcc taatgctagc gaaaggagtg gataaataga
     2041 aaaattcaaa aaactggcaa cgctaccgaa aatattacca ataaacagta tcaaaaagaa
     2101 aaaaacgctt aaaattaaac catctgtcag cgacatctga aaaacaatgt tctctacctc
     2161 aattggctgt tgaatcgaat agacacctaa gtatatactg agaaggagac ttagcacgtg
     2221 gctggcacaa aacacacgat tgaccgtttt cattttaatc acctaaccta tctttataat
     2281 tctattataa tcattttatc atttttttgt atgtataaag tttcaatttt tcttcactta
     2341 cgattttttt tgatattgtt gttatataaa tgaaaggagt tttacaaatg attgatccaa
     2401 aaatgttggg gatgatcttc ctcattaatt ttgcttatat cactctgaac acgttacgtt
     2461 tcatgttgac aatgaaaggc tatcgactga ttgctccact tgtcagtatg gtcgagatca
     2521 cgatttatat cgtcggctta tcccttgttt tagatcgttt agataatcca ctgaatttat
     2581 ttgtctatgc gttaggttac gcagtaggta tcagtgtcgg aattttgatt gaagacaaat
     2641 tggcattagg atacatcatg gtcacaacga ttttgccagc aaatagcgca gaagataaaa
     2701 gtttgccggg tatactgaga gaacacggtt atggtgtgac acagacttct gcaatggggc
     2761 tggaaggtga gcggctagtt ctcgaaatac tttctcctag aaaaagcgaa cgtgaactgt
     2821 atcgcctgat caaagaaatc gaagagcgtg cttttatcat ttcttatgag ccaaaatata
     2881 tttcaggtgg tttctggact aaaaaagtga gaaaacgaca aggaaaataa ctcacaaact
     2941 taaaaactgt ctaatatcta aattaaattt taaatgttag acagttttta tttattattt
     3001 tgattaaaaa acatcgacat atactcatca atttgttatt atactttata tacttatcaa
     3061 tttaatttgg agatattatg gaaattcaac gtagaaccac taatttttta catttaggct
     3121 ctttttttgc aactttgacg atcttatttt ttctatgtta ttcatacctt aagacctcac
     3181 atgcgccttc tagtgcatta ggctggttgc ttttggatca ttctgatatc acagaagccg
     3241 aagaaaatcc gttttttttg attttgtctt ctctttgcgg cttactgttt tctgtttatt
     3301 tcggtgccta tttttttcat cgacatcctg gtacgttaaa cgaagcttca agcgtattga
     3361 ttgcatttaa aacgttttct tttttagcaa ttctttttta ttcgtttaat cacaatacgc
     3421 ttttcttctt tatcatgaat ggtttagtcg tgattttatc catttttact tattttattt
     3481 tttcactcat ttttagccaa ttgaaatgtc cgctcttctt tcgattagtt cctgtcacct
     3541 gttttattta cagcttgttt tccttttttg tccttgcttt aatgccactg accaaccctt
     3601 cgacgatcca agtcgcagga aatctgttgg atatgctctt catcgtcagt ctaggtgtat
     3661 ttatgtggca aagaaaaaac aaacaaaata aaaagcattt tgaagcctga ctattacgac
     3721 ttcataaatg cttttttagt tttaaacact tcaatctaaa agaataaccc aagattggat
     3781 aaattattaa tgactcgcca ttcgtttctt agtgattctg gattatcaaa tggacttcct
     3841 aatctaatca gctagttctt cccataaaat gccatacttg actgaatcat aatattgatt
     3901 atttaaaaat ctaacttttc ttatcactac ttcctttgtc attccacatt tctcaccatt
     3961 tttttgcatt cctttgtttc cagaccatgt agtgaatcta ataggtggta gataggcaaa
     4021 atactcaaat aattctttta accataaagg aagagaaagg ctcctcctgc aagagtcagt
     4081 ataatttttg cttactgctc tcttaggttt tactcactaa aactgttcca tattctttga
     4141 tataagaaaa tgcatgcggt ataaatttct tgctcagctc agaaaagatt tgtcgtttaa
     4201 gaaaggccat ttcctccatt gtcaatgaag gatccaatgt tggtaattca atctcaaaat
     4261 tgtttttttc gacaataggt aattctaatg tgaatgattc ttcttccttt atagtattcg
     4321 tcacaagtag agactgatgg aaaatactag gccggcgatt tttatattta ttcttacgta
     4381 tcctgtcaac gataacttct atttgatcaa aaaagtacga ttcatttacg tctccaataa
     4441 gttcggctaa ttctttgaat gccttcgtta caggaagctg attcttctgt acaaaaaagt
     4501 aattagccaa agtaagcggg aagtgttcta tagaggaaag tgtgataaaa cggtacttct
     4561 catttcctgc agttgtcctc agcaattctg tctctcggct gtttcttact ccataaaaat
     4621 acgcttcttt ccgttcatct tcgaaacaat acgcccaaat aacttctccc atcgctaatt
     4681 tttgttcatc aacagagagt ctcttcaatt gttcagctat ggtttcagca gccgaagtgg
     4741 cttgttgcaa gtaatcttta ggatcaaata ttggaaagtt caaatgatat cttcgttctt
     4801 ccctcttgat taatcctgca tcgatcaata aatcaagaaa atgggaaaat ttattttgcg
     4861 aaaattcttt tttcaattct cttagaatcg tttcttgttc tcgatgttca tatagataat
     4921 cggtcaatga agaaaaaagc ggatcatcgg tcagtttttg ataaaagttt tccttatttt
     4981 ttgaataata gttcatatat gttctctttt ctatccgttt tattttactt aaaaggcttt
     5041 tacgtaaaaa ggaggaagaa caagagtcat aattgactgt tattctcctc catttcttcg
     5101 gcctttagta tgttctatgt ttctttttat atcaatcgct tatccattca ttttgaatgc
     5161 ttcatactac catttgatta gctaaataca gccgtcaatt gaggtacgac ttgtttttta
     5221 cgtgaaacga cacctttaag caaagcacgg ttgttggtca aagttgtttg gaaagcttct
     5281 tctacttttt cttttccttt accagcaaca agtaattctg aatcactgtc taagatgttt
     5341 gtgacaacta atacgaacag atcgtagcca tttgctttca tttcatcttc cattgctgct
     5401 tctagctctg cttgtcgatc catcacttca ttaaggtcca ctgtattgac ttgagcgata
     5461 cgaacgttgg aactgcccat tgggaaactt tttgcatcca aatcaagaag aaccgcagct
     5521 gatttatcac ttagatttgt tcctgctttc aacatttcaa gtccataagt gtttagatcg
     5581 acttcagcga ttgctgcaag ttcttttgca gctgcttcat cttcaggcgt acatgttggt
     5641 gatttgaaca acaatgtatc tgaaatgata gctgagagca tgattcctgc gatttcttta
     5701 ggaattgtta cttggttttc tttatatagt tttaaaataa tcgtacttgt acatccaact
     5761 ggttctgcac gatagtacaa tggattagct gtttcaaagt ttgcaatacg atggtggtct
     5821 actacagcta aaatatttac ttcgctgata tctgaaatac tttgttggaa ttcattatga
     5881 tccacaagca tgacatctgc attttctgct ttagctgact ctactactcg tggtgcagat
     5941 agctgaaagt ggtctaatgc gtattgtgtt tcttcattag gtgtacctag agcaactgct
     6001 tctgtttctt tacctaattc attttgcaag tgtgaaaacg caatggctgc cccgattgca
     6061 tctgtatctg gattttggtg accaaaaact aaaatttttg acatgtcatt cgctcctttg
     6121 tgatttctcc tatttaataa tagcaaaaaa acggaaagaa gcaatactta tcttctttcc
     6181 gatgcgacct atcgcgttaa atattttgta tactcttctg tatgaagcaa tcgtttagca
     6241 ttttcgacac gttcttttgt aggtggttcg atcccttcta atggatattt caaaccaagt
     6301 gtttcccact tgtattttcc catcgtatga taaggaagaa tctctactct gtctacattt
     6361 gacaaggttt gaataaagtt gtctagtcgg atcaaatatt catcataatc acttcgctca
     6421 ggaactagta catggcgaat ccaaaccggt ttgttgattt ttgacaaata ttgagccatt
     6481 tctaaaatat tttcattgtc ccaatgcgtt agttttttat gctcttcatt atcgatgtgt
     6541 ttgatgtcaa ataacagtaa atctgtatac ttcatcaatt cttgaaaacg tgaaaagaaa
     6601 ggttcttcat acgtaaaagg ttttccgcat gtatccaatg tagtatgcat cttccgctct
     6661 tttgcttttt taaatagttc gatcaaaaaa tcgatctgca atagaggttc tccaccacta
     6721 acagtaatac cacctttatc tccccagtaa ggtctgaagc gttctgcttt atctaaaagt
     6781 tcatctgctg tgtattcttt ccctccgcca atattccaag tatctggatt gtgacaaaat
     6841 tggcaacgca tgcggcatcc ttgcataaac acgacaaagc gcagtccagg tccgtctact
     6901 gaaccgaaag tttcgataga atgaacatag ccgattgttt tttcttccat ttaagttcac
     6961 atcttttctt tgatttcatt ttaagtacaa gttagctgtc gaagcgaagc tttctgaaca
     7021 aaatttttcg caattgccgc ttcgttatgt gtaaaattta cagggacgga acatacaagt
     7081 cctgcccctg taaatcgttt ctttcaaata agcatactga ttattcgatt ttgatgcgat
     7141 ggctattcaa cgtcctttcg acgctaagtc gaaaaacttt tttcacgaac tttttacatt
     7201 ctgtcgtgtg aagttctcat caagacatct aattgttgtt ctcttgtcaa gtcacggaat
     7261 ttaactgcat aaccagatac ccggatcgtc aagttcggat atttcattgg attttccatt
     7321 gcatcacgca ataaatcatt actgaataca ttgacattca aatgataagc tccttttgag
     7381 aagtatccat ctaagacatt acgcaagttt tcgattcttg tatcttgttc ttttccaaga
     7441 cctgaaggat tgattgtttg ggtatttgaa attccatcca atgcacagcc gtaattcatt
     7501 ttagctgttg agttcaggct agctaataac ccactttgtt ccgcattgta acttggattt
     7561 gctcctggcg caagtggttt tccagcttca cggccatcag gagtatttcc tgtattttta
     7621 ccgtaaacaa catttgaagt aatcgtcaat aatgaagttg ttggttttga gttgcggtaa
     7681 gttttatgac gtttgatttg tcccatgaag tattccaaga tccatgaaac taattcatct
     7741 gcacggtcat catcatttcc gtatttaggg aagtcgccat ccacttcaaa atcaactgct
     7801 attccttttt cattacggat tgcttttact tttgcatatt tgatcgctga caagctgtct
     7861 gccgcatgag agatcccagc aatacctgta gcaaatgtgc gttgcaagtc agaatccatc
     7921 aaagccagct gagctgcttc ataagaatat ttatcatgca tataatgaat gatgttcaac
     7981 gtattgacat atagttctgc taaccaatcc atcatattca tgaagttatg tttcacttct
     8041 tcaaagtcta gtatttctga tgtgattgga cgatattctg gtccaacttg ggcgccagtc
     8101 acttcatcga ctccgccatt gatggcatat aatagtgttt tagccaagtt agcacgagcg
     8161 ccaaagaatt gcatgtcttt tccgacaact gttcctgata cacagcaagc aatcgcacaa
     8221 tcatcagaac cccattgttc acgaagctga ttatcatttt cgaattgaat cgaagaactt
     8281 tcgatagcga ttctgctagc atatgttctg aatccttctg gaaggtgttc agaatacaaa
     8341 acagtcaagt ttggttctgg tgaaggtccc atatttgtta atgtatgaag cagacggaaa
     8401 tcattctttg taactaatga acgaccatct aatcccatac ctgcaatgga taaagtagcc
     8461 cagataggga atcctgagaa taattggtta tattcaggtg tacgcgcgaa tttgaccata
     8521 cgtaatttca ttactaagtg gtcgatcaat tcttgtgctt ctttttctgt gattactcca
     8581 ttatccaaat cacgttggat atagatatca aggaatgctg agatacgtcc gattgacatc
     8641 gcagcaccat tttgtgattt gattgctgct aaatatccga agtatagcca ttggacagct
     8701 tcttttgcat ttgcagctgg tttagaaata tcatagccat atttcgcagc catttctttc
     8761 atttgcgcta atgcacgata ttgttcagtg atttcttcac gtaaacgaat cacttcttca
     8821 ctcattgtat gataaccagt catatcatga tcttttttct tttgttccat caaatagtcg
     8881 attccataca atgccacacg acgatagtca ccgatgatac gtccgcgacc gtaagcgtct
     8941 ggaagccctg taatgatttt gtttttacga gcagcacgca tttcagcagt ataagcgtca
     9001 aatacacctt gattatgtgt tttgcgccag tcagtgaaaa tatgtgtcaa ttcatcgttt
     9061 ggtgtatagc cattgctttt tagcgcattg ttagccatat tgattccgcc gaacggcatg
     9121 aatgcttgtt tcaaaggttt gtctgtctgt agaccgacga ttttttccaa atctttatcc
     9181 aaatagcctg catcgtgtga agtaatagtt gatacgattt ctgtgtccat atcatagaca
     9241 ccgttacgct cgaattggat atcatttaac ttttgcaatt catcccataa tttttctgtt
     9301 gcttctgttg ggccttccaa aaagctgtca tcaccgcgat attcagtgta gttattttga
     9361 ataaagtctc tagtgtctac gccttctttc catttggtac ctttaaatcc attccattgc
     9421 tccattgtat ggacctccta aatttctgtt ttatgtaaca gtttttacgt gattagtata
     9481 acacagcacc ctatctttgc aagggttttc ttgtttttta tttaacaatt tttatgtttt
     9541 atttacatat atttaaatca acgttgacat accaacattt aagcattgtg aacactttca
     9601 tctttttttg caaacgtata aggatttatt aaaaatgaat gaaaaagaga cgccacctgt
     9661 attaatacag atggcgtctc ttcattaaaa tactacaaca gttacgactc gatgaaaatc
     9721 tcaggagcat cgataacttc gatgacttct ccaccttttt tctcatccat cgcaaatgat
     9781 ccattcgatg ttcgatcacc tatagggaaa tcagttgggt caatcgttaa ctgctgccct
     9841 ttttgattca tcaaggttat ttcttttgat cttccttccg acatatagat aatacggtgc
     9901 ggattttttt tcagctcacg catgaccgtc actccccgct tcgcacgtga agtttggctg
     9961 atttcttgag caagcatgcg tttaacagct cctcgctgag taacgattac gatcggcgta
    10021 tcaccttctg ctaacacaag cagcccgttg ataatcctat ctccatcttt caaattcata
    10081 gacttcactc cagctgcctt tgctccaaca acgggaacat ctgttaaagg atagcgcaaa
    10141 cccattcctt gatgcgttac taagaaaaca tctaagcctg gctgatcttc tttcagatac
    10201 acagcaatca gttcatcttc ttccgccttt agcttcatac agctgagcgg acggctctta
    10261 taggtgcgcc atggttcgaa ctctgtcatt cgtgtttgct tgatcaatcc attcttgctg
    10321 atgaatacaa atgttttctc tgcttgaatt ttttgatatg ggaaaacagc taaaatcgat
    10381 tcgtctacag acagattgga gattgtttga gaaatgtgct caccagcatc tttccatttc
    10441 aaatcgggta gttcatggac agggcggtag atcacatttg ctttatttgt gatcagaaga
    10501 acatggtcca atgtactcaa ttcacctgag tatagcaagt agtcgccttc tcgcatcccg
    10561 atttcttctg gtttggaagc actataagaa cgaaggcttg ttcgcttcac atagccttct
    10621 cgcgtcacac tgacaattac gtcttcttgt gccactaaga cttgcgtatc aattttgatt
    10681 tcttcgattt cgtcttcgat tgtcgttaga cgagcggaag aataattttt tttcacttct
    10741 cgcaattctt ttttcataac agagaaaagc tctttgtcat ttgaaaggat tttattcaac
    10801 tctgtgattt gcgcaatcaa gctttcggat tccttttgaa gctctgtgat atccgtgttc
    10861 gtcaaacggt ataattgcaa tgtgacaatt gcttctgctt gttcttctgt aaattgaaag
    10921 acgtcgacta aattcttttt ggcgtctttt ttgtctttac tttcacgaat cgttgcgatt
    10981 acttcatcca gaatcgataa agctttcatc aatccttcta cgatatgctg tcttttttga
    11041 gctttggcta aatcgaattg actacgtttt gttatgactt gctttcgatg ctcgatataa
    11101 cttcttaaaa tgtctttcag tccaacttga tgcggagtca tatggtcgat agcgaccata
    11161 ttgaaattgt aattgatctg tagctcagtg tttttgaaca aataattcaa aattccttga
    11221 gcattggcgt cttttttcaa ttcgacgaca atttgcagac ctgttctatc actttcatct
    11281 cgtacttcag ctattccatc gattttctta ttcaaacgga tctcatccat ttttttcacc
    11341 aaggtcgctt tatttacttc atatgggatt tctgtgatca cgatttgctg tttattaccc
    11401 ttcattgcct ctatctttgt tttcgaacga agaataactt ttcctcgtcc tgtttcataa
    11461 gcttttttga tttcatcttt tccttgcaag atccctcctg ttggaaagtc aggtccagga
    11521 atatattcca tcaatttttc aaggctcgct tgtggatgat cgatcatata gattgtgcca
    11581 tcgatcactt cagctaagtt atgagtcggg atttctgttg catatccagc agatatacct
    11641 gtcgatccat tgacgagaag gtttgggtat cgagctggaa ggactgttgg ttctttttct
    11701 gtatcatcaa aattccacac gagatcgact gtttctttct cgatatctgc tagcatctct
    11761 ccacttaact tggataatct ggcttcagta taacgcatcg cagcaggtgg atcaccgtcc
    11821 atactcccgt tattcccgtg catttcgatc agtacttccc gcaacttcca gtcttggctc
    11881 atgcggacca tcgcttcata aatactgatg tcaccatgag gatgataatt ccccatgata
    11941 tttccgacag attttgctga tttacggaat cctttgtcat acgtattgcc atctttgttc
    12001 atggcaaata atatccggcg ttgcactggc ttcaatccat cacggatatc aggcagtgca
    12061 cgttcttgga taatatattt ggaataacgt ccgaagcggt cacccatcac ttcttctaaa
    12121 gttaattctt gtacttcttg tcgattttcc atcaggtgac ctcctattct acttcaaata
    12181 actgattgtt ttcattttta tctgctcgtt cttcatctaa taaatcatta gaaactgaag
    12241 gagagatttc agtatcctct tttttatcta agatactgcc atcttcttcg agcgtaaatt
    12301 gcacgtgatt ttcgatccat tttcttcgag gttctacttt gtcacccatc agtgtggtta
    12361 ctcgacgttc agcttgcgca gcatcatcga tacggacgcg gatcaacgta cgggaagtcg
    12421 gatccatcgt tgtttcccac aattgttccg cattcatctc tccaagtcct ttatatcgct
    12481 gcagcatata tcctttgccg acttttttaa tcattgctgc caattcgtca tctgtccacg
    12541 catattcaat gacttgcttc tttccttgtc ctttggatac tttatataaa ggcggtaacg
    12601 cgatatatac tttcccagct tcaatcagcg gtttcatata acgataaaag aaagtaagca
    12661 gtaatacttg aatatgggcg ccgtctgtat ccgcatcggt catgatgatt actttgtcgt
    12721 aattacagtc ttcgatagaa aactcaggac cgactcctgc accaatcgta tagatcatcg
    12781 tattgatttc ttcatttttc aagatatctt gcattttagc tttttcggta ttgatgactt
    12841 ttcctcgtaa aggtagaatt gcttggaact ttctgtctct tccttgttta gcagatccgc
    12901 cagcagaatc cccttcgact aaatacaatt catttttctt agggtttcgg gattgtgcgg
    12961 gtgtcaattt tcctgaaaga agagattcgc cttttttacg cttcttccca tttcggcttt
    13021 cttctctggc tttacgtgct gcttctctcg cttctctggc tttgattgct ttacggacca
    13081 acatctggct catttcgcta ttttcctgca aataaaagcc catttgttca ctgatgacgt
    13141 tatctactac ggtacgagca actggcgtac caagtttttc ttttgtttgc ccttcaaatt
    13201 gcagaagatt ttcaggtaca cggatagaaa gtacagcagc taacccttct ctgaaatcac
    13261 taccttccag attcttgtcc cgttctttca gcaaaccaac ttttctcgca tattcattat
    13321 aagatttcgt catcgccgct ttcataccag cttcatgggt tcccccatct tttgtccgaa
    13381 cgttattgac aaaagataaa acattttctg aataaccgtc attgtattga taagcgacct
    13441 ctacttcgat accttctttt tctcctgaaa aataaacaac tggtgtcaat gtatcttttt
    13501 cttcattcag ataatcaaca aattctttga ttccttcttc gtaatgaaaa atttccttga
    13561 ctggttcttc tccacgaaga tcagaaagag agattttaac gccttttaga agaaaggcag
    13621 attctcttaa ccgttcggct aaaatttcat atgaaaattt cgttgtactg aatattgtat
    13681 catctggtaa aaaatggaca gtcgtcccgt ttgctttttt tgtttttcct atctttttca
    13741 aagtaccgtc aggtttaccg ccgtttttaa atttctgctg atactctacg ccatctctaa
    13801 cgatcgttac aattagccat ttcgataagg catttaccac actggctcct acaccgtgca
    13861 gtccaccaga agttttgtac cctccttgac caaactttcc gccagcatgc agcacagtaa
    13921 aaatcacttc aactgttggt attccggaag catgcattcc tacaggcatc ccacgtccgc
    13981 tatctgcaac agttatacta ttgtcttcat ggatggtcac atcaatctca ctgccataac
    14041 ctgataatgc ttcgtcaact gcattatcga cgatttcata gactaaatga tgcaagcctc
    14101 ggctgtcagt ggatccaatg tacatccctg gtctttttct aactgcctct aatccttcca
    14161 atacttggat ggacgagtca ttgtattcgt tgtttacttt ttttgccaag gcaaacgctc
    14221 cttcaataat actttgcggc aaaaccgcac cacgattatc atactagaaa aggtcgtgaa
    14281 aaaaaagagg gtagacgaga aatcaatttt aattatctcc taaccgcttt ttcgacattc
    14341 ccctctatcg atcatctctt ctttgtggtc atttttattt ttggttttct ttcaacttac
    14401 caagttcaat cttaatacaa cgatccatta cgatatctgt acgtcctgct tttcttagca
    14461 tctcagctgc ttctttgttt tcaatcccta attgtgccca gaacacttta gcatcagttt
    14521 tcaaaaaatc acctgctatt tcaggtaaaa attcactccg tctaaataca tctacgatat
    14581 cgattggatc atcgatttct gtcaaattcg catagacttt ctcgcctaga atttcttcac
    14641 cagccaataa tggatttact ggtatgattt tatatccatt gtcttgcaat acctgtgcaa
    14701 ccatgtaact tgttcgttct ggtttattgc tcaagcctac gacggcaata ttttttgctt
    14761 cttccaaata gttgaaaatc gtttcttgtg ttggattttt tacagacatt tctgccaccc
    14821 cttgcttttc tttttattcc atctattata cttgtatctt tcattttttc aattgttcct
    14881 gttacctatt catgctaaaa taaaggatag ttttcaactt gaaagagggt aaaaaatgaa
    14941 attgatctta ttacttattt tagcatatct tttaggttct attccttccg gtgtctggat
    15001 tggcaaattg tttttcaaaa aagatatccg acaacacggg agcggtaata ctggaacgac
    15061 caatacattt cgtgtattag gcaaaacagc cgggattgtt gtcctgctta tggatatttt
    15121 aaaaggtaca ttggctactt gtttgccgat gatcttccac ctttctggga ttaaccctct
    15181 ttggtttggg gtatgcgcca ttcttggcca tacatttccg atttttgctg ggttcaaagg
    15241 aggaaaagct gttgcgacaa gtgcaggaat gcttttagga tttaatcctg tattttttgt
    15301 ttattcttgt atcatcttta tcgttagttt attttgtaca agtatggtga gtttgagcag
    15361 tatgatcagt gcagtattga tcactttatc tacgatcgtc cttccttatg tagctcctgt
    15421 gattttggct aagcccaatt ggttactgac gatcattgcc tttttagttt cttcctttat
    15481 cttttatcgg cataaagaca atatcaagcg tatcagaaac catactgaaa gtcgaatccc
    15541 gtttggtttg aatagcagca agaaaaaatc ctgatacttt ttcattccaa agagataaaa
    15601 cgggagtgtg acaaatcgat gtcacactcc cttattactt acaggatagc ttttttacac
    15661 accttggtaa acggtgttcc ctgctaactt ctcggtcaca acctcttact tcactgtgat
    15721 ggaatatttt gtcttgaaga tttcatgggc acctagttga ttgatcccta ctttttccat
    15781 caagtttcca ctactgttca ccgtgtcagc gattccgcac cacggttcga tacaaacgaa
    15841 aggcgcttct tttggataag gagaccagat ccctacataa ggcatatctt tatagcttaa
    15901 agttacgcta tgggaagatt tttcacttcg aatggcgtac gcatttagac cccttgtttc
    15961 aaaaaccaag gcatcttgct caaaaagttc acgattcaaa gccagattcg tatttgtctg
    16021 acctaacgtc ttttgatcca tatcgatgaa tgggcctttc aatggtaggc gtaatcttga
    16081 tttcaatgga gaaaatgcca gatagaaatc ttcaaatgac aatccttctt caagaggtac
    16141 attgaaagca ggatgtccac cgatagaaaa gaacatttct ttttcaccgg tatttgccac
    16201 ttgataatga accgtgatgc cgtctcctcc taattcatag ctgatcacta attcaaaatc
    16261 aaatggatac ttttctaatg tctccggcgt actccttaag atgaaactag ccatttcttg
    16321 tccatgttca atgacttcaa aatccatatc ccgagcaaat ccgtgttgcc ccatttgata
    16381 tgttttccct tgataaacat actgatcatc ttttaaacgt ccaacaaaag ggaataaaac
    16441 cggtgcatgt ctgccccaat acgctggatc accttgccag atatactcta aaccatgttc
    16501 ttttgatttc agactgatca attccgcacc gtgttcagcg atttcggcga tcagctggtc
    16561 attttgaata ataacagtca ttgccattcc tccaacttcg acttactttt taaaatggga
    16621 aggctggaac aaacatttct atctgcccca gtccccttac ttctaataac tgtgttttgc
    16681 taactcgtct ttaaaacggg aattcaatac ttttaaataa gttcccttca tgcctaacga
    16741 acgagattca atgattccag ctgattccaa ttttcgtaaa gcattgacga tcacagaacg
    16801 agtgatgccg atactatcgg caatattaga agcagtcaga cgaccttcat ctccatccaa
    16861 tgcttcaaag atagcttgta cagccttcaa ttcgctataa gataatgtgt tgattgccat
    16921 ttggacagcc gttgcactcc gtacatctgc ttcgatgctt cgagacttct gataaaggat
    16981 ctgcataccg acaaccgtag ctccatattc tgctaagact agatcgtcat ctgcaaacga
    17041 ttgttccata cgagataaga taatcgtacc caaacgttcg ccagctccaa agatcggaac
    17101 gacagtcgtc agaccaaatg gatatttctc tcttgactct accggaaatg cagtaatatc
    17161 actagtaatt gggatattag cttcagtttt catcaactgt gccactgtat cagtataaga
    17221 ttcaggaaat tgtttctcaa caaacattgt tttgattcgt tcattgttca catcgtgacg
    17281 ttcattataa cctagtaata ctccgtcact tcctatgata taggtgttgc tgtcaagaat
    17341 accacctagt gtgacagcca ttttatcgta aggcaaatct gcttgcatgt caaaagtatt
    17401 cttttgctgc aaaagtgtgt ttatcttgcg ggttttcgtt agcaagtctg tcattgtcgt
    17461 cctccgattt tttataaaat atagcgactt aaatcttcat ttgccgcaat tgagccaagt
    17521 ttgtcatcca catatgcttc tgtgatcgtt atttctccca tttgcatatc tggtgcttca
    17581 aataatagat cttctagtag tttttccaaa atggtatgca gtctgcgtgc gccgatatta
    17641 tctgtgtcac ggttgacatc gaaagcgatt tgagcgatcc gttcaattgc ttcttttgta
    17701 aacgtaactg acacattttc tgtaccgatc aacgcgacgt attgttttac taaagcatta
    17761 tttggttcgg tcagaatctt cacaaaatct tcagctgtca aatcatctaa ttctacccgt
    17821 atcgggaagc gtccttgaag ttctggaatt agatcacttg gtttagacaa atggaaagct
    17881 cctgaagcaa tgaataggac gtgatctgtt tggatgatcc cgtattttgt gtttacttgt
    17941 gaaccttcga caattggcaa tatgtctctt tggacgcctt ctctggatac ttctccagat
    18001 tgctgtgatt tagaagtgat cttatcgatt tcatcgataa aaataattcc actttcttcc
    18061 gctaatttga ttgcctcact atggatatca gcatccttga ctaattttgc tgattcttcc
    18121 ttgatcaata actctaaagc ttctttgact gttaccgtcc gttccacttt tttcttcggt
    18181 gtcaaagcac ctagagtttc atttaggtcg atccccattt gctccaatcc attgttcatc
    18241 attggtgcag gtttcttttg gtcttcaact tcaatggtta cttcacgact atccagtaaa
    18301 cccttttgta gttgttccaa gactgtacgg cgattgattc gaatatcttc tgtcacttct
    18361 tcttgcggtt cagcggtatt ttgctgacta gcattaaaaa gattcatcat ttgttcaaat
    18421 tgattagtgg attgtttctg ttcttttttg ataccaggta ccaagatttt taccaaacgt
    18481 ttttctgcat tttttttagc acttgtgtat acacggctgt actgctcttt ttctacgatt
    18541 tggatcgcat tttctactaa atcccgaacc attgattcta catctcttcc gacataaccg
    18601 acttcagtaa attttgttgc ttcgactttg acaaatggtg cattgacgat ttttgccaaa
    18661 cgtcgtgcga tttctgtttt accgacccct gtaggtccga tcatcagcat attttttggt
    18721 gtaatatctt gttgcatttt ttcatctaac tgcaaacggc gatagcggtt acgcaaagca
    18781 acggcaacag atttttttgc tgcgtgctgt cctacgatat attcatctaa ttcacttacg
    18841 atttgtcttg gtgtttgttt taattcatac atatctactc acctcttaca gttcttctac
    18901 gataatatta tgattagtaa agatacagat atctgcggca atatttaacg cattttctgc
    18961 aatttctttc gcactcatgt cgttttgagc atagtttttc attgctcggg ctgcagccaa
    19021 cgcaaaattc cctcctgatc cgatagctaa gataccatca tctggtgtga taacttctcc
    19081 tgtacctgaa acaagaagca tttctttatc attcattacg atcagcatcg cttcaagttt
    19141 ttgcatagat tgctgtgtcc gccattcttg agctaattcg acagctgcgc gttgtagatt
    19201 cccgttatat tcgtttagtt tgccttcaaa tttttcttct aaagtaaacg catctgcaac
    19261 acttccggcg aaacctacaa caacttctcc attgtagata cgtcgtactt tctttgcagt
    19321 gcctttcatg acaacagatt cacccattgt tacttggcca tctccagcca tagcaaattt
    19381 cccgtctttt tcgacggcac agatagtggt tgaatgaaat ggtgattcga ccatgtttgt
    19441 ttcctcctaa atttgttctt ttccttattt ttacgctctt ggatggaaag aacgatagtt
    19501 tttttgtaaa ctttcttttg ttacatgggc atagatctgg gtagtcgata aattggcatg
    19561 tcctagcaat tcttggactg tccgcaaatc tgccccatta tttaataaat gagtagcaaa
    19621 tgtatggcgc agcatgtgag gatggatatc actatccaaa ctgctttttt tgatcatttg
    19681 attcaagaca tattcaattc cagtaggcgt gattggtttt ccatgatgat tcacaaaaac
    19741 gatatcatgc tcttcgtgat attttgtcat caatacctgg cggccttccc tgaaatattc
    19801 ttgcagagca tcttgagcaa aagaacctag aggagcatat ctctctttgt tccctttacc
    19861 atggatcaac atgacctctg aatcaaaatc aatgtctgat accgacaaac tgctacactc
    19921 acttaaacgg atgcctgacc cgtaaaggac ttccagtaaa gcgcggttcc tcaaatccaa
    19981 aggactatct cctgctacgc tgtcaaaaag tgcttgcatt tcattttcat aaaaaaaacg
    20041 tggcagtctc aaatttttct ttttgagatg aacgtaagaa aatggatttt cttttatcac
    20101 ttcttctttg agaagatact gataaaacga acgtaggctg gctatcttgc gactgataga
    20161 atttctgcta tagctaggac gatgatcagc taatgcactc aaatagacac gaaccgtaaa
    20221 atattccgcc ttcagcagat cagcgtctcc agattcctcc aaaaaatgtt tgaaatggag
    20281 aatgtcttct tcatatgctt ctttcgtttt ttctgaatat cctctttcga caatcaaata
    20341 acgcaaaaat ttttgttccc acgtggcttc tgtcattttc tcaccttcct tttgtcccag
    20401 agaataattt agcacagcgt ttataaaaag acaaataaat tgtcagaatt taaccaatat
    20461 ttctaagttt gttcacaatt ggcgcaattc ctcacatttt gtttgagaaa ttcttaagaa
    20521 aaacgcaaga aaaagagcga gactatccgt ctcaccctct tcatggagtt tccttactca
    20581 tttgggattg cagttttttc taattctgtt tttattgcct cattagcttt taaagctcgt
    20641 tgtgcaattg cttcatatct tgcttttttg tctcgaatgc gctctggcag ttcaggaaac
    20701 agaccatagt tggcattcat cggttggaaa tgttttcctt ccgcatgagt aatgtagtaa
    20761 gccatacttc caatagctgt ttcttgtgga aactcgactg gttccatttc ttttgctaag
    20821 cgtgcggcgt tgattccagc aagtagtccg ctcgctgcac tttcaacata gccttctaca
    20881 ccagtcatct gacctgcaaa gaacagatct tcgcgtttcg ttgattggta agtcggtttc
    20941 agcaattctg gcgaattcat aaagctgttt cggtgcatca caccatagcg aacgaattca
    21001 gcattttcta acccaggaat catccggaaa acacgttttt gctcgcccca tttcaagtga
    21061 gtctgaaagc ccacgatgtt gtataaagaa gctgcagcat tgtcttgacg cagctggata
    21121 acagcataag gacgtttgcc agttttagga tcttccaatc caactggttt cataggtccg
    21181 aaaagcatcg ttttgaatcc tcgctgtgcc attacttcaa ttggcataca tccttcaaaa
    21241 tatttttctt tctcaaaaga tttaagttct gccacttcgg cattgattag tgcctcatgg
    21301 aaagctttga attcctcttc tgtcatcgga cagttcaagt aagctgcttc tcctttgtca
    21361 tagcgggact tcaaatatac tttatccata tcgatcgtag ctttgtctac gattggtgca
    21421 gctgcatcat agaaataaaa accatctgaa ccattgaatg ctttgatgct ttctgctaat
    21481 ggatgagaag tcaaaggtcc tgttgctact acggtgattc cttccggtat ttcagtaatt
    21541 tcttcgttta tcactgttac taatggatgc tctttgactt ttcgggtaat tgtttcagaa
    21601 aaagaatcgc ggtcaacagc taaggcacca ccagctggca ctgctgtttc atctgccgaa
    21661 gtgattacta ccgaattcaa tcggcgcatt tcttctttca ataaccctac tgcattagcc
    21721 aaactgtttc ctcttaatga attggaacat actagttcag caaaattact tgtgtgatgc
    21781 gcctcagtcg atttgactgg acgcatttca tataaacgga cagggactcc tgcttgtgcg
    21841 atctgccaag cagcttcact tccggcaagc cctgctccaa caacatttac cattttcaat
    21901 gaaagaacct cttttctatt atttttggat gtcttcttcg taatctccat ttacacagac
    21961 tacttgttta ccgcctttga ctttcttctc gaccagatat ccgtcacatt ttggacaatt
    22021 tctgcccact ggtttatccc aagaagtgaa ttcacattct gggaaacggg aacaaccata
    22081 gaatagtctg tttttcttag attttcgttc aatgacttgt ccttcatgac atactgggca
    22141 agtcacaccg atttctttta cgattggttt cgtattccga caatcaggaa aattactgca
    22201 agcataaaac ttcccatatt tccctaattt tatcaccatc ggatgtccac agacatcaca
    22261 atcgaatcct gctggttcat ctttgatttg aattttttcg attttttctt ccgcattcgt
    22321 cagttctttt tcaaacggtt tatagaaacg atcaaccact ttgacccacg cttccgtgcc
    22381 ttcttcaatt ttatccaaat ctccttccat ttctgctgtg aaatggatat cgacgatttg
    22441 agggaagaat tcacagatta atgaattgac aatttctcct agttcagtcg gctcaaatct
    22501 tttttgtgtc aattttacat agtagcgtct ttggatcgta tcaagtgttg gtgcataagt
    22561 ggaaggtcgc cctaccccgt tttcttctag tgcacgaatc aacgtagcct cactaaaacg
    22621 tgctggtggt tgagtaaaat gttgttttgg ttcaatatca acagattgga ctacatcgcc
    22681 ttcttcaagt tctggaagaa tattttcttt ctcttctttg ccgtcatctc taccttccac
    22741 atacacttgc atgaatcctt tgaatttgat ttttgaaccg ttcgcaatga agatgacacc
    22801 attttgttct aatgtcactt tcattgtatc taaaatagct ggtgtcatct gactagccac
    22861 aaaacgtgac cagatcaatg tataaagttt caattgatct ttatctaaat attgtttgag
    22921 ttcatctggt gtacgaagca cactcgttgg acgcacagct tcatgggcat cttgtgcgcc
    22981 ttgagcattt ttgatctttc ggtgaccatg tctagaaaat tcttttccat acgtatcttc
    23041 aataaatgct gcggcctctg cttttgctgt atcggcaatc cgggtagaat cagtacgcat
    23101 gtatgtaatc aagccgactg ttccttgttt acccaaagtg attccttcat ataattgctg
    23161 tgctaccatc atggtttttc ttgttcgaaa gtttaactta cgggcagctt cttgttgcag
    23221 gctacttgta gtgaaaggat tcgcagggtt tcttttgcgc tctttctttt ctactttttt
    23281 aacttcgaag tctgttccat caattctagc agtgacttct tttacacttt gtgcatctgg
    23341 taatttcttt ttcttaccgt cgattcccca gaaatttgct ttgaatttct tgcgagcttt
    23401 tttaaaatta ccgtcgatgc tccaatattc ttctggaaca aattctcgga tctctttttc
    23461 acggtcaata ataattttta aagcgacaga ttggacacgt cctgcactta accctttctt
    23521 gaccttacgc cagagaatag gactgatcga ataaccaacg attctgtcta aggtacgacg
    23581 agcttgctgt gcatctacta aatctacatc gatcgttctt ggttccttaa aagctgcttt
    23641 gactgcgtct tttgtgattt cattgaagac cacccgattt ttttctttca gatccaaccc
    23701 aagtaggtac gctaaatgcc aagcaatcgc ttctccttct ctatccgggt cacttgccaa
    23761 gtaaactttt tgagcttttt ttgctgcggc tttcaggctt ttgatgacat cgccttttcc
    23821 gcgtatagaa atataatggg gttcataatt gttttcaaaa tcgataccca ttttactttt
    23881 cggtaaatct cttatatggc caacactggc cattacttta tagtttcgtc caagatattt
    23941 ctcaattgtc ttggcttttg caggtgattc tacaatcact aaatatttat acgccattac
    24001 tgaatggact cctttccatt gtcgtgttcc tactattaaa agaggattca tacaaatcgt
    24061 agctaatcat atccattcag aaaacgtttg tcaagaaaag caaatgaaaa gtatggtgtt
    24121 attctttaaa ttctgccaag atatcttcac ccgaaaccgt gcaaactgca ccgtcttgga
    24181 tcaaatgatg acatccggta gaatgttctg ttaaaatatt tcctggaaca gaaaaaactg
    24241 ttcttccaag atccaatgct tgctgtgctg ttatcagaga gccgcttttt ttcttggctt
    24301 caaagacaca tgttccttta gacaaagctg cgataatccg atttctcatt ggaaaacaat
    24361 gctttttcgg gccggattga ggaggatatt cactcaaaag aagatgatca tttgcaatca
    24421 cctcttgcaa gtcacgattt tcagcaggat agacttgctc tatccctgtt ccaatgactg
    24481 cgattgtccg tccaccatga gagattgctg cttggtgacc gtatgtatct atccctttcg
    24541 cgcagccact gacgatcaca tatccagctt ctatcactgg ttttagtaaa taataaactg
    24601 tttttttggc taaagcagaa gtgtgtcttc caccaacaac gcttaacatg ttacaagaaa
    24661 gtaaagatag atcaccatta taaaacagta caattggcgg ataggtcaag tgaagcagct
    24721 gagggggata tttgggatca aagcaagtga taaacgactg tttcgattgg attttgcccc
    24781 agttagcgtg aatttcctgc caacttttgc gaaacagctc ccggtgtttg gttattttac
    24841 ctatcttaat gatgtcttca aatccgattt ctttataagg atactgcatc atccagttag
    24901 caagtgccca ttttccttga ctactgattc cttttgtata agcaagtttc aataaatttt
    24961 cttctatttg atacatcata aaaccgcctt tcgtctctct ttctaataag atacgtaaaa
    25021 gcggctgttt tttattgtaa atattttttt acaggtgcaa aacttttacg atggattggc
    25081 gtaattcctt gtcgttcaag tccttctaag tgttcctttg ttccataacc tgcattatgc
    25141 gagaaaccat atccaggata aagcacgtca tattctttca tcaattggtc tcgatatact
    25201 ttagcaatga tacttgcagc agcaatcgac acagatcgtg catccccttt gattattttt
    25261 tcctgctgaa taggcaaatc caaggtcatc gcatcgatca acaaatagct tggtacaatg
    25321 gacaattttt ctactgcttg gatcatcgct aatttacttg cttcataaat attcacatca
    25381 tcgattgtct gctgatcaac gatcccgatc ccgattgcca gggctttttc ttgaacttgt
    25441 tgataaagaa gttctcgctt tttctctgat aattgtttgg agtcattcag ccctaatatg
    25501 atctcatttt tcggcaagat aactgcagct gccacgacag gtccagctaa tggtcctctt
    25561 cctacttcat caatgccggc aatccattgg tgaccttgtg cgtacccttg cttttcaaag
    25621 caaaacattt cttcatattt ttccttaatt aatgcttcct ttttcaatcg tcgttcaaaa
    25681 gaagccagtg cttgctgcac gcctttgcgt ggatcatttc ttaatgattc tagtgtagga
    25741 tcatctattc tctgtatgct tttcaatcgt tctttgatac tttggatgga ttcagtcatc
    25801 acttttttgc tccatttctt cgcaacgatc cagtgtgtat cgtccaagtt ttccttgacg
    25861 aatatcatgc acgactaatt cgctgccacg atcatagtct tctttatacc cacgttttgc
    25921 tgtaatatcc atcagtaatt ccggtgccaa tttttcttct tgctcgattg ataaaccata
    25981 acgatcgctg attcttcctg aataatatcg ggcaaaaaag tctaatccgt aaatcgctaa
    26041 atcatctaaa tggacaagct ggtctttgat cgcgcctgtc agcgctagtt ttttgccgat
    26101 ttcttcatct tcaaatttgg gccataaaat ccctggtgtg tctaacaatt ccaactcatt
    26161 acctaaacga agccactgct gaccttttgt tacgccaggc ttatttcctg tctgtgcaat
    26221 tttcttgcct actagtcgat tcatcaacgt agatttccca acatttggaa tacctaagac
    26281 cattgcccga atagcgcgag gcttgatccc ccgagcagca tctcttgccc gtttttcttt
    26341 caatgcttct ttagccgcag gtactagacc tttaattcct ttactttctt gtgccgtgat
    26401 agctaatgca agatggcctt gtttacgaaa atattcttgc cacagctttg tctgttgtgg
    26461 atctgccaga tccgctttat tcaataaaac aaggcgaggt ttttgctgaa tgatctgatc
    26521 tagcattgga ttacgagaag ataaaggtaa tcgtgcgtct accaattcaa atacgatgtc
    26581 cacatatttc attttttcag aaacttctcg tcgggctttt gccatatgtc ccggaaacca
    26641 ttggatggtc attgttctct ccattccttt cataccggaa tattccccgg ctttacttgt
    26701 ttttttcttt ttcaatataa attcactttt ttat
//
LOCUS       DAKCAA010000037        24866 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000037 DAKCAA010000000
VERSION     DAKCAA010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.037"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..129)
                     /locus_tag="OUE31_001675"
     CDS             complement(<1..129)
                     /locus_tag="OUE31_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCU0222686.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDS"
     gene            437..1243
                     /locus_tag="OUE31_001676"
     CDS             437..1243
                     /locus_tag="OUE31_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222687.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            1255..2475
                     /locus_tag="OUE31_001677"
     CDS             1255..2475
                     /locus_tag="OUE31_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222688.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     NKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2465..4051
                     /locus_tag="OUE31_001678"
     CDS             2465..4051
                     /locus_tag="OUE31_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCU0222689.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVVQTSIAQPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSEAT
                     ERMVFRFAQQPSFIEFSAEAAGEKLIFIDSNAVVKTVNDCYLFDGKEIPEFALTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENQHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKKTSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSRDEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            4090..6228
                     /locus_tag="OUE31_001679"
     CDS             4090..6228
                     /locus_tag="OUE31_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCU0222690.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKIRLSGKMRGKAILDFQTAKHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKTIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNIHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKKLGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            6516..7907
                     /locus_tag="OUE31_001680"
     CDS             6516..7907
                     /locus_tag="OUE31_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCU0222691.1"
                     /translation="MNKNGEWNAARRIFIIIMDVLVLNVSIYLSFLLKFQGEVPARNL
                     ETFQHSAVFISIIFIALNILLGAYVFYSRVISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVIVLSFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVVIDKYYENTKKLIDDIDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFKIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSVTAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENIRS
                     LAEIDFSQEKIYR"
     gene            7966..8775
                     /locus_tag="OUE31_001681"
     CDS             7966..8775
                     /locus_tag="OUE31_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCU0222692.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFNHMTVMFD
                     KNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYARRGGSKYL
                     LPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN"
     gene            8747..9736
                     /locus_tag="OUE31_001682"
     CDS             8747..9736
                     /locus_tag="OUE31_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCU0222693.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLKRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNCGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNYPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQKE
                     KQKYYNQSKREIKSIYSKIRSNNEISIAKKLALFLYLINPKTYFILYKKVLKK"
     gene            9850..10845
                     /locus_tag="OUE31_001683"
     CDS             9850..10845
                     /locus_tag="OUE31_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCU0222694.1"
                     /translation="MHKISVIVPAYNVEDYLENCLESISNQTHSNIEIIVVNDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILIFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDYLRS
                     INILQRFEKEVKIDPDFSPKLKKLVKFLLINKNLPYYMSSSKIASKFLIKIESVR"
     gene            10849..11991
                     /locus_tag="OUE31_001684"
     CDS             10849..11991
                     /locus_tag="OUE31_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HCU0222695.1"
                     /translation="MKNIKKFFSRNIFPVFIKILPIQKNLIVFSSFGGRNYSGNPRVI
                     SEKIHEKKLNYRIIWLIKKEAIITDLPDYIKRIDSDSFLAAFYLYTAKYWIDDSRKTI
                     KYAKRKKQLYFQTWHGTPLKKIEFDAKDKLPKRYLSYAKKDSESITYLLSGNRYSSKK
                     YVSAFNIVPSKILEVGTPRNDELASSKEQVFDLKKKQINVLFAPTFRNNIEDNGITQL
                     EWLGVDNLREFFKKQQQELNFMTKFHPNVHSKLATDSKSIEYMKKHQITLINDGIPLE
                     MLFEEIDVLITDYSSIFFDFALTKKPIILFNYDEKEYSLERGFYIQLSELPIISVQDS
                     YGLVDVFKNQQEKLLKSSQELLDYIGNYETGASTEKVLELIERDIK"
     gene            11988..13415
                     /locus_tag="OUE31_001685"
     CDS             11988..13415
                     /locus_tag="OUE31_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HCU0222696.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFIQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIVGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIIIFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPIFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTELSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVILFFIVNLTLTTWAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEIRKITRK"
     gene            complement(13482..14771)
                     /locus_tag="OUE31_001686"
                     /pseudo
     CDS             complement(13482..14771)
                     /locus_tag="OUE31_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(14951..15361)
                     /gene="tagD"
                     /locus_tag="OUE31_001687"
     CDS             complement(14951..15361)
                     /gene="tagD"
                     /locus_tag="OUE31_001687"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HCU0222697.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGQFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            15487..16878
                     /locus_tag="OUE31_001688"
     CDS             15487..16878
                     /locus_tag="OUE31_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HCU0222698.1"
                     /translation="MLNEKFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFAINIFIQFS
                     FIALSGSRTTLVCLLIATFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAQAWAHVPHITEIKKDISDSSGTTSSNKVDLKRPDTDGGDVSNLRFGLWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKTLRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            17011..17958
                     /locus_tag="OUE31_001689"
     CDS             17011..17958
                     /locus_tag="OUE31_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HCU0222699.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDME
                     KQVTFIEGDVSDPQLMERIMKQYQFAYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFASEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(17998..19158)
                     /locus_tag="OUE31_001690"
     CDS             complement(17998..19158)
                     /locus_tag="OUE31_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCU0222700.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            19323..20498
                     /gene="mltG"
                     /locus_tag="OUE31_001691"
     CDS             19323..20498
                     /gene="mltG"
                     /locus_tag="OUE31_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HCU0222701.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPNGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEKAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            20634..21113
                     /gene="greA"
                     /locus_tag="OUE31_001692"
     CDS             20634..21113
                     /gene="greA"
                     /locus_tag="OUE31_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HCU0222702.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            21281..22012
                     /locus_tag="OUE31_001693"
     CDS             21281..22012
                     /locus_tag="OUE31_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HCU0222703.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            22009..23076
                     /locus_tag="OUE31_001694"
     CDS             22009..23076
                     /locus_tag="OUE31_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCU0222704.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEIAKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            23083..23715
                     /locus_tag="OUE31_001695"
     CDS             23083..23715
                     /locus_tag="OUE31_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0222705.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDCPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            23855..24520
                     /locus_tag="OUE31_001696"
     CDS             23855..24520
                     /locus_tag="OUE31_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HCU0222706.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            24548..24841
                     /locus_tag="OUE31_001697"
     CDS             24548..24841
                     /locus_tag="OUE31_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HCU0222707.1"
                     /translation="MELTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
BASE COUNT         8473 a         3698 c         4812 g         7883 t
ORIGIN      
        1 agagtcatcc aattttcctt taataaactg cgcttgaacg cctttatatt ctttttcaat
       61 cagccattct tcatcaaaaa ataaatgttt atctgttaat ccgagtaatt ttctagtatg
      121 attatccatt gagagactcc tttggtagga tgacgttttg gtcgactaaa ttttaccaaa
      181 agtgagtctc tttttgagtt taaacgaaga aaaagtgtta gtagaaaatc gccttcgatt
      241 ttccaccaac acaaaatatt atagaacccc ttttttggtt tattgcaatt gtctagcatc
      301 ttctgtaaaa tagaaacgtt agagaaaatc ttgtatcata gaaaattaag aaagaaataa
      361 gaacgcagct cggtaccaaa aatatggtaa aatggcactt gactgtaatt cactgaaatc
      421 gcttggagga acacaaatgt ttaaagattt gtatttattt atgaaagaca tttatcagaa
      481 tagaaaatta ctgctacagt tttcgatcaa tgacttcaaa tcaagatatg caggatcgtt
      541 tttaggaatc ttatgggcgt ttatcaatcc gctatttact gtattgattt attggctggt
      601 atttggtgtt ggactgaaag cacaaatgat cgatgcaaaa tacccattta tcgtatattt
      661 agttaccggg atgattccct ggttcttctt ctcagatgca tttgcatcaa ctacggttgt
      721 ttttcgggaa tatacttatt tagtaaagaa agtcgtattc aatattcgta tcttgcccac
      781 gacgaaaatc ctatccaatc tgtacaccca tttattcttc attctgattg gcatagctgt
      841 cgcgcttata aatggtatat atccttcagc aatgtcttta cagctgattt attatttatt
      901 ttgcatgtgt gctttcttga caggattgac ttggctgacg gcatcgatcc aaccattttt
      961 acctgatatc atgcaattaa ttacgatcgt gctgcagttg atcatgtgga cattaccgat
     1021 attatggagc cctaatcagt ttgattcagg tcttgtaagc atattgaaat taaatccgct
     1081 gtactatgtt gttcaaggtt atcgtgagtc atttttaagt gaagcttggt tctgggagca
     1141 tggaacatat actttgtatt tctgggtttt cacgttagta atgttcgtaa tcggctctgc
     1201 agtgttccgt agattgaaac cacatttttc agatgtgctg taaggagaat agctatgaca
     1261 gaatatgcaa ttagactaaa agatatcaca aaatcttata atatgtacgc aaaaccttcg
     1321 gatcgatttc gtgaagccct caatcctttt aagaaatcct atcatgatgt attttatgcg
     1381 ttgaaaaacg tgaatgtaga aataaaaaaa ggtgagatga tcggtttcgt gggagaaaac
     1441 ggatcgggaa aatctacaat gttgaaaatc attacgggag tactgacacc aacatccggc
     1501 acgatggaaa tcgaaggaaa aatctcagct ttgctagaac taggatcagg attcaatcct
     1561 gagtattctg gctatgaaaa tatctattta aatggaatgg ttctaggatt ttcaagagaa
     1621 gaagtcgatg aaatggtcga tgatatcatt gaatttgctg atattggcga ccatatttat
     1681 caacctgtaa aaacctattc aagtgggatg ttcgttcgtc tagcttttgc tgtagcgatc
     1741 aatgtgaatc ctgatatttt gattgtggat gaagcattgg cagtaggaga tcttgaattc
     1801 caactgaaat gtatggaaaa atttacagaa attaagaact cgggaaaaac gattttattc
     1861 gtttctcatg atattagttc gattcgccgt ttttgtgatc gttcctattg gttgaaaaat
     1921 ggagaagttg tcgaatatgg tgatacgatg gaagtaacga cgaattacga aaactttttg
     1981 aagaaaaaat cagttaaaac agtagatcga aataaaaacc aagtagaacg cttcgcagct
     2041 ccagatatcg tagacgtgac gaaagccgaa ttgttggata aaaataaaaa tccagtggat
     2101 atgctggaac aaggagaaaa actatacgtt aaagtaacct atgaagtaaa agacgataca
     2161 atcaaaaatc cagttttagg aattgctctg cgtacagtcg acaattttta tgtgtgcgga
     2221 ctcaatactc tactagatgg tatcaagatc ccttggaaaa aaggtgagaa tatcttttat
     2281 ctggagtatg aaaagttagg tttgttagct ggtgaatatt attttgacgt tgcggtcttt
     2341 gaagaaaatg caacggttcc tttggtatac aagacaaaat acatgaactt gtttgtcagc
     2401 ggttcttata tcggagaagg catcgtggtc ttagaccata aatgggaaga agggactcat
     2461 agcaatgaaa tatgattttg aaatggacct agatgaacaa agcagtgtgg gaaaaattgc
     2521 cgcacagatc aaaccaggaa gtaaagtttt agagtttggt cccggaaacg gtcgattaac
     2581 gaaacatttg atcggagcaa aacaatgtga agtgagcatt gttgagctag ataaggaatt
     2641 attcgatttt gtcagcgaat ttgcccaaga tggattttat ggagatatcg aaagttttga
     2701 atgggcaaac tattatgctg gacagacatt tgattacgtc ttgtttgcgg atgttttaga
     2761 acatttagta gatcctggaa aaacattgaa gaaagtcaga gaatttttga atgaagaagg
     2821 agagatcctg attacattcc ctaacttagc acataattct gtcatgatcg atttgttcaa
     2881 taatcaattg ccttgggctt cttatggtct cctagatgaa acccataatt ctttttatac
     2941 tcatgatggt ttccaaaaag tttttgaaaa agccggatta ttcattaata ttgaagatta
     3001 cttgtacttg gctgtaggag atacagaatt aaaatcaact tatgaagagt tgccggaagc
     3061 tgtacgctat gatttcaaaa tgcgaccatt tggtgaagtc taccaatact ttttctcatt
     3121 gatgaaacat ccagtagtac aaacttccat tgcacagcca caaaactcta attatgtaaa
     3181 agtactagaa gtaacccagc aaacgaaaca agatgaaaca atccaacaaa taccattcaa
     3241 taatttcaca ggggaaaatg agacactaag tttccccgtg tcagaagcaa cagaaagaat
     3301 ggtgtttcgc ttcgcacagc aacctagctt tatcgaattc agtgcagaag ctgctggaga
     3361 aaaactcata tttatcgatt caaatgctgt agtcaaaaca gtaaatgatt gttatttgtt
     3421 tgatgggaaa gaaataccag agttcgctct aacggatatt tctgggaaag aagtgactat
     3481 ccattgtcac tatcgcttta tcggggaatt gacaccaaca atgaaagaat tgctggaaac
     3541 aattcgtcct atggctgaag tcacaaagca gctttctgag aaaaatgatg aattagaaag
     3601 agaaaatcag catcttcttg aggaaaatac aagactagac catacgttaa aaacaaccac
     3661 aaatcgctat tgcacattgt tggaaagtga tgaatggacg atcaaacata gactaggacg
     3721 acgtaagaaa aaaacatcga aaaaaataca agaaaaagag ctttctatat gtattgatga
     3781 gaaaatatgg gatgcagaaa caaaaatatt aaaaatcatc ggatggggaa tcgctaattc
     3841 ggatcgccag ccattgtcct ataagttatc agctgaccaa tcgccatttt tcgaagcaat
     3901 tcctgtttca cgagatgaag tcaatcaagc agaacagctc gcaaaaggaa cagaagcggg
     3961 atttgaatta cgaatccttt gcgagcaaga acgttcattc ttagtggaag cagtagctca
     4021 aaatggtcaa tcatggatca ttgaaatgta aataatgatt aacttataaa gataaggagt
     4081 aaacgaatcg tgcaaaaaaa agaaattgcc gtatttatcg atcaaatcac tcgtgaacgg
     4141 gccactggcg atttgcttat tgtgggctgg gcaattgatg aagtgaccaa agaaatccct
     4201 acgataaagg tagaaaaaga aaatgtgatt gctgaagcaa cacatgtcgt aagattggat
     4261 atcaatcatt tatataatct tgatgttaag acccaaagcg gttttaagat acgtttatcc
     4321 gggaaaatga gaggaaaagc gatcttagat tttcaaacgg caaaacatca aaatggcata
     4381 gctgtgaaac taaatggtaa atacccttat gatgacggca ttgaatcttc atgggaaaga
     4441 aaaaaaagat tactgaaaaa agggataaat tatgcaagga ctcatggcgt aaaaaaaaca
     4501 atccgccggg tcaaactgga attgaaacca ggatcgatcg actatgcaga gtggatcagt
     4561 cgtcacgaga aacctgatct gaaagagcaa aggaaagaag cacaagggtt tgcataccgt
     4621 ccattgattt ccatacttat gcctgtctat aacgttgaaa tcaaatggct cgaaaaatgc
     4681 attgattcgg tattggatca aacgtatgat cactgggaac tatgtatcag tgatgatgct
     4741 tctactgatc cagctatccg aaagtgtctg gaatcctatc aagcaaagga tgatagaatc
     4801 aaagttgttt tccgacaaga aaatggacat atcagtctgg caactaattc tgcgttggaa
     4861 atggcagaag gagaatttat agcgctctta gataatgatg atgaattacc gccatttgca
     4921 ttatatgaag tggcaaaagt gctaaacata catccagaac tggatttgat ctacagtgac
     4981 gaagataaaa tcgatgcaga tggcaatcgc tttgatccgc acttcaaagc agactggtct
     5041 cccgatacat tgatgggaaa taattatatc tctcacttag gcgtatatcg aacaagtatt
     5101 gtgaaaaagc ttggcggttt ccgtaaaggc tacgaaggct ctcaagatta tgatttggtc
     5161 cttcgtgtga cagaacaaat ccctgcagat catatttacc atattgaccg agtcttgtat
     5221 cattggcgga cgatcccagg atcaaccgca agtaatggtg aagccaaaag ttatatctat
     5281 gattctggag tgaaagcatt gacagatgcc ctgtctagaa ggaatatcaa aggaagcgta
     5341 cgtcctggca gaatttctgg attttatgag attgcttatg acgtcttgca agaggatttg
     5401 gtcagcgtga tcattccaac gaagaatggc tatgaagatc taaaaacttg tgtggattcg
     5461 attatcgaaa aaacgtctta tccaaattat gaaatcatta ttgcagataa tggaagtaca
     5521 gatcctaaaa tgcaggaatt atttgcagaa tacaagcatc agctgaaaga ccgatttatc
     5581 gttgaattaa ttgacattcc attcaattat tcacgtatca acaatctggc agcagaaaaa
     5641 gcaaacggca aatacttttt attcttgaat aacgatacag aagtgattga acctgactgg
     5701 atgacagcga tggtttctta tgcacagttt gatcgaatcg gctgtgtagg agcaaaactg
     5761 ttttatccag atgatacaac gcagcatgca ggagtattat taggaatcgg tggtgttgca
     5821 ggacatgcat tgaataacta tgatcgaaca cattgtggtt atttcggccg attggtcatt
     5881 gacgtcaatt acttagcagt cactgcagct tgtatgatgg tcaaggcagc tgacttcaat
     5941 gctgtcaatg gatttgatga aacattagaa gtagcattca atgatgttga cttgtgtttg
     6001 aaagtttatg aactgggtcg ttacaatgtc tatgcacatc aagcagaatt gtatcatttc
     6061 gaatctaaat caagaggtta tgaagataca ccagaaaaac aaagacgttt tgccggggaa
     6121 ataaaaaaaa tgcaagataa gtggccttct tatattgctc atgacccatt ttataacgat
     6181 aatctaacta aagaaggaat cggcgatttt tcattgagac ctgattgatt aaaagaactg
     6241 tattttcatt tttattgatg aaaatacagt ttttttagta tatgaaaatt gtaacttgtg
     6301 accgaagaga tgataggaag aacacccatt cagtaggaag aatgtgatac gatttttgtc
     6361 caactctctg ttaggcagaa atatacatat aaacatacaa tagtcacctt ttctagtttc
     6421 ttttaattta ttttacaatt tggttattca ctaggttttt aaactttgct atggtaagat
     6481 gatagaggca ttattttatg gttaggagtg tatatatgaa taaaaatggg gagtggaatg
     6541 cggcacgtag gatattcatt atcatcatgg atgtacttgt attgaatgtg tcgatctatc
     6601 ttagcttttt gctgaagttc caaggagaag tcccagcaag aaacttagag acctttcagc
     6661 attcagcagt ttttatttcc attatcttta ttgcgttgaa tattttgtta ggagcttatg
     6721 tattctatag ccgagtgatc agtgatatcg tcttcattac tgttattgga caggtgctga
     6781 tagcattggg gatcatggta gttacttttg ctggacgttg gtttgcattt ccgcgtggcg
     6841 tcatcgtgct ctcgtttata cttggcacga tattacttag cgtttatcgg atagttgttt
     6901 ataaactata cttaagagtc agtcgtgata agaaagtcct tatcgtaggt ttggagaaag
     6961 atgtcgcacc agctatccaa aactttcaat ctaagaaaaa caacaaacat aaagttgaag
     7021 cagtagtgat cgacaagtat tacgaaaaca caaaaaaatt gattgatgat atcgatattg
     7081 tctacttggc ttctaaaatc ccagaagacg aaaaaatcaa tatttatcaa ttagtaacta
     7141 aaaaagagaa gaagctattt ttaaatacaa cttttgaaaa tttaacgatg atcaatccga
     7201 acatcatgaa tttcgaagat gaaagtatca ttgaagcttc cggtttcaaa attcagccgg
     7261 aatatgaatt attcaaacgt ctttttgata tcatcgtttc gcttatttta ctgattcttg
     7321 cttcaccttt tatgctaatc acagcgattt tggtaaaaac aacttcacct ggaccaatta
     7381 tttataaaca agtacgtatt acgaaaaatc aaaaggaatt ttcaatctat aaatttcgtt
     7441 ccatgagtgt aacagctgaa gcaaaatcag gaccggtctt ggcaaagagc aatgatgcac
     7501 gtgtgacacc agtaggcaaa tttatccgtg ccgtacgttt tgacgaatta cctcaaatct
     7561 ttaatgtatt gaaaggcgat atgtcgatcg tcggaccacg tccagaaaga ccatttttcg
     7621 ttgatcagtt caatgaagaa aatccttatt attatttaag acacaatgta cgtgcaggga
     7681 ttaccggata tgcacaagta tacggaaaat atgtatcaga ttataatagt aaactacgtt
     7741 ttgatttgtt gtatatcaaa aagtattcct tactattaga tttgaagatt ttacttcaaa
     7801 caatcaaaat cttatttgat aagatgtcct cacaaggact agatgaagat gaaaatatcc
     7861 gttcgttagc agaaatcgac ttttcacaag agaaaattta tcgctagatg ggaaaaattt
     7921 tgagcaaaga agtaggagag aacattggaa aataaaaata taagtatgct gctttcttta
     7981 tatgataaag aaaaaccaga gtatttaaag gaagcattaa ctagtatttt tgagcaaaca
     8041 gtaatgccaa aagaaattgt attagtttat gacggcccta taaatgaaaa acttcaagta
     8101 gttgtcactt atttccaaca aaaagatcct cacttgttta cagttgtaaa attagaaaaa
     8161 aatcaaggat tggggattgc tttagcaatt ggattagaac atacgaaaaa tcgcttagta
     8221 gccagaatgg atacagatga tatcatggaa ccccaacgat tagaaaaaca attagagatc
     8281 ttccaaaaag atccagaaat agcgattgtt gggagtaata ttgaggaatt tactggcacg
     8341 cttagcaatg ttatcggaag aaggattgta cctgaatata atgatgaaat ccgtgtgttt
     8401 tcgaaaagaa gaaatccctt taatcatatg acagtcatgt ttgataaaaa tgctatttta
     8461 gaagtgggaa actatcgccc attaattgga tttgaagatt attatttgtg ggtaagactg
     8521 ttgaaggcgg gatataaagg gtataatatc caagagattc tagtccatgc tagagcaggt
     8581 gctgacatgt atgctagacg tggaggaagt aaatatcttt taccaggaat taaaggccga
     8641 tatcgcgtat ggaaagatgg tctaggatca ctaaaagatt ttctgatagt tatttgcgga
     8701 catcttgtaa ttagtttatt accgaataaa attaggggaa aagtatatga atcaaaactt
     8761 agaaaaacaa actaaacttt ctataatcat acctttttac aatgcaaaaa atactttaaa
     8821 aagagctgta gacagcgtct taacgcaagg ttatcccaat attgaaatct tgttaattga
     8881 tgatggatct acagatggta gtagtgacat tggtgacgaa attgctaatc tagagagtaa
     8941 agtagcatgt tatcacttgg aaaacgctgg tccatcagtt gctaggaatt gtgggataaa
     9001 agaagcaact ggaaatttgg taggattttt agatagtgac gattattttt tacctgattg
     9061 ttttaataat gttttgaaag actaccatag gaattacccc gatatcattg cttttggatt
     9121 aagtaaagga aaaaatatag aaaatgcaaa tttatttgtt cccgaaaaga agattggttg
     9181 ttcaagtgaa gaagcaattg agcaaatgtt tagaagtaag gcagtggatt tttacgtatg
     9241 gaataaattt tttaaaaggg aattattcaa tcatatagtt tttccagaaa ataaattata
     9301 tgaggatatg gttcctatgt atgaagcttt tagagcggct agtaaaattg atattttgcc
     9361 attttcaggt attttttatt atcaaaataa tgatagcatc gtttatcagt cttttaattc
     9421 aaaacagtat gataatattt tgcaaagaaa aatattagtt gatgaagtaa agaaagatta
     9481 tcctcgactt attaatttgg ccaatgctcg attagtagac ggataccttt caacagggtt
     9541 taaaattact ggcaagaatc aaaatcagaa agaaaagcaa aaatattata atcagtctaa
     9601 aagagaaata aaaagtatat attcaaaaat aagaagtaac aatgagatat caattgctaa
     9661 aaaattagct ttatttttat acttaattaa tcctaaaact tattttattt tatataaaaa
     9721 agttctaaaa aaataaagtt tttttcgata tgttattttt tatgtttatt aacttcggaa
     9781 gactaaaatt gttactggta atgatacatt tgtaaaaata aaaaagatga tttttaggaa
     9841 gtgaagagag tgcataaaat tagtgttata gtacccgcat ataacgtaga agactattta
     9901 gaaaactgct tagaatctat ttccaaccag acacattcaa atattgaaat aatagtagtc
     9961 aatgatggtt ccccggatcg aagtggggaa attgcagaag aatataaaaa gaaagatatg
    10021 cgattaaaag tgatacatca agtgaatggt ggtttaagtg cggctaggaa ttctggtctt
    10081 gattctgcaa caggagattt tgtgtgcttt attgacagcg atgattggat agaaccagac
    10141 tatcttgagt tactatattt tggcacgcaa acttatggag cagatatctc ggtgctaaaa
    10201 ataaaaaaga tttcaagttt agaacaacta aaagaacata caattgctga gagaaaatgg
    10261 gaaatatttg atagagaaca agcaatgaaa aacttattta taaataataa aattggctat
    10321 tctgcaaata ataaattatt caatagaaat ttatttgata atataagatt cccactgggt
    10381 aaattaatgg aagataaggc tactacttat ttgctgatcg atcattccga aaaagttgct
    10441 gtcaattcat ctgctaaata tcactattac caaagcccta aaagtatact gagaggaagc
    10501 ttcaatccta gaatttttga ttcttttgaa gtccatgaag atatactaat attcatagat
    10561 aagttttatc cggaattatc aattaatgtt agaactcgct atgtctatga agcaataagg
    10621 atgatgatga caatgattaa aaataactat accaataaag aagattattt acgttctata
    10681 aatattttac aacgctttga aaaagaagtg aaaattgatc ccgacttttc accaaaatta
    10741 aaaaaattag taaagttttt attaataaat aaaaacttgc cttactatat gtcaagtagt
    10801 aagatagcaa gtaaattctt gattaagata gaatctgtga ggtaagagat gaagaatata
    10861 aaaaaatttt tttcaaggaa tattttcccg gtttttatta aaatattacc tattcaaaaa
    10921 aatttaattg tattttcaag ttttggcggg cgtaactatt ctggaaatcc aagagttatt
    10981 tcagagaaaa ttcatgaaaa aaaattgaat tacagaatta tttggttaat caaaaaagaa
    11041 gcgattataa ctgatttacc agattatatt aaaagaattg actccgattc ttttttagct
    11101 gccttttatt tatatacagc taagtattgg atagacgata gtcggaaaac gattaagtat
    11161 gcaaaaagga aaaaacaact ttattttcaa acatggcacg gaacgccttt aaaaaaaatt
    11221 gaatttgatg caaaagataa gttacctaaa cgttacctaa gctatgcgaa aaaagatagt
    11281 gagtcaatta catatttatt atctggtaat cgctatagtt ctaagaagta tgtttcagca
    11341 ttcaatatcg ttccttctaa aatattagaa gtaggaactc ctagaaacga tgaattagcc
    11401 tctagtaaag agcaagtgtt tgacttgaaa aagaaacaaa tcaatgtctt atttgctcca
    11461 acttttcgaa ataatattga ggacaacgga attacgcaac tagaatggtt aggtgtggat
    11521 aacttacgtg aattttttaa aaagcaacaa caagaattaa attttatgac taaatttcat
    11581 cctaatgttc atagtaaatt agcaactgat tctaaaagta tagaatatat gaaaaaacat
    11641 caaattactt taattaatga tgggattcct cttgaaatgc tttttgaaga gatagatgtt
    11701 ttaatcacag attattcatc tatttttttc gattttgcgc taacaaaaaa accaattatt
    11761 ctttttaact atgatgaaaa agaatatagc ttagaaagag gtttttatat acagttaagt
    11821 gagttaccaa ttataagcgt acaagatagt tatggccttg ttgatgtttt taaaaaccaa
    11881 caagaaaagc ttttgaaaag ttctcaagag ttacttgatt atattggaaa ttatgaaaca
    11941 ggagcaagta cagaaaaggt tcttgagttg atagagaggg atataaagtg aaaaaaacag
    12001 taaaagatat attttataat gcgatatatc aagtcttttt gattgtttta cccttactta
    12061 ctatacctat acttagtcgt agaattggtt caactggttt agggatttat gggtatgttt
    12121 tctcaatatc acagttttta atgactgtca ttgctgtggg aatgaatcct tttcgtattc
    12181 gaaatatcgc taaatcaagg aaagataaaa aagcactatc tttacaattc tggaatattt
    12241 actttattca atttttaata ggcttgagtg tttcctttct ctatatagcc tatatttatt
    12301 tttttgatgt aaagtataaa aatttatact taattcaatt gatatttatt gtagggctaa
    12361 cattagatat ttcttggttt tttcaaggaa ttgaagaatt ttcgaaagtg gttattagaa
    12421 atacagttat caaattatca tcggtattgt taataatcat ttttgtttca actaaagatg
    12481 atttgtggat ttacgtgttc attacttcaa ttactaactt tttaggaagt ttagttttct
    12541 ggttaagtat ccacggaaaa gtaggtaaac caatctttaa ctctaatgtt tttaaacagt
    12601 tgtggaaacc agcttttatt attttgactc ctcagttgtt tatgcaagtg tacacaactt
    12661 tagacaaaac gatagttggg tattttgtgg atccaacgga attatcttat tatgatcagt
    12721 ctcaaaaaat tgctcgtatt atattggcag tcttaacatc aattactatt gttatgttgc
    12781 ctaaaatatc taaagcacag gcagagggga aatcagaaaa tattttagtt tacacaaaaa
    12841 aatcttttga ttacacgatt atcattgcat taattctttt tagtgtggtg tttatcaata
    12901 caaaagaatt tgttccatgg ttttttgggg agaatttcaa accgatgaca ataaacatgc
    12961 ttatttcttg tctaattata gttgttagtc caattggtgg agtttttgct aaccaatttg
    13021 caattgctat agaaaaagat aaggagtatg cttatccaat gatcattggt gcgattgtaa
    13081 gtattattgg aaatgtagct tttgtgccta cttatggcgc tgtagcggct acgatcgtac
    13141 tcgtggtagt agaattatta gtctttttct ttagagtatt ttttgtacga aaagaaataa
    13201 aaatatccta tttctttggg aagaacgtta tcttattttt tatagtcaat cttactttga
    13261 ctacttgggc ctattacttt cttccacaat tattctcttc ttcattttta gatatggcaa
    13321 ttaaatcaat aatgattttc attatttatc ttccgtttgt ttattttctt tttccagata
    13381 tacgaaatga aataagaaag attactcgaa aataaaataa tgttgtaaaa aagtagttct
    13441 ttgtcaaatc gggctgataa ggtcatttat gaacaacaaa gttagtaaga gttactagct
    13501 tttaatgcat agctgattaa cctgttgatt agaaaaatcc acaagcgcat attggtaaaa
    13561 ctgcgaaacc cataagcaaa tcgtttcaat gttttgatat gtgtgcgaag attctctaat
    13621 tttgttatta gaatactttt tcgaaaatgc tagttaaaag cctttttcag atatgaaaaa
    13681 ggctttttga gatagtgaag tttcgaggga acttctttgg tcgtttctcg aagtagctag
    13741 ctgtttcttg tgataattgc taagcagctt ttgataaact gcttagcaat tttaagttca
    13801 taagagattg agggtagacg atcaactact tcactttctg ttaaatagcg ccattgaaaa
    13861 ttctgccatt tcttgaatgt tgtgtaatcc aactcgtcat ctgattttag aagtaattta
    13921 tacaaaggtt tcaattgtcg atagtactta gcttgtgaag tgtctttttg attcaactgc
    13981 ttcatcacac gttttcgaac acgatcgaaa aacttgttca agtgttgtcc aatgtgaaag
    14041 caatcaatga tgatttgggc gtttggaaag gactctttga ctaatgaaaa ataaggggca
    14101 ttcatatttg tgacaatgta tcgaaccccc atatgagctt ttcttgtaaa acgcatgaaa
    14161 taagcaatca aatctttttt tctccggctg gacaaaatgt caaagagctt ccctgtctct
    14221 ctattcatac aagaaaagga gaactttcca tgggaaattg aaagagagcg aaactcgtcg
    14281 aatagtaaac aatgaggtaa atagtctagc atctgtcgca gcattgccga tagagcagat
    14341 aatgtccgtt gaaatgtcgt tactgaaaga tcacaacgtt tcgtaagtgt ctttaacgct
    14401 tgacgctcgg tcaactcttc taatatcgtg taatgaactt gtttcgaaat aaaacatgaa
    14461 ggaacgacaa gatacgtatg agcagtaaaa tattttccgc atgattggta gtggtaatgt
    14521 tgttttctaa gacgcaaata ggtttattta ttcccactgc gatttaagat aatcattgaa
    14581 atcttcttgc cgtttttcac gagctgcttc gcagtttctt tacaaaatag acaatgtcta
    14641 aaagtgcgaa ctaatgtacc ttcgattacg atggctttct tgtccttata aaaagttttt
    14701 tgaaaagaat taatttcaat atttttatct ttaatagtga agtgctcttt gatagaacga
    14761 gaaatggata tacaaaatct tcctttcaga ttgatgtttt agacgactct attttatcga
    14821 aatttttgta tgtctgtttt ttttacaaga aaatctagga tcgacagaaa attctatcag
    14881 tcctagaaat tatagagcca tttttttacg tcttatccag atatattgtt ctttcattgt
    14941 ttaaaaaata ttatttatca ctatttaaag aattaagttc gttctttatt tgagttgtag
    15001 agatctcagg tgttcttggt aaataaatta cttgtgcatc tgttagttgt tcaagttcat
    15061 caaattgtcc agcccaatca tcgcccatca cgaaataatc tgcatggtat tcttttatat
    15121 cttttacttt ttgttcccaa ttttcttcag gaataactaa atcaacgtag cgaatagctt
    15181 caagtaactg ttttcttttt tcataactaa aataacattt tttttgtttc gcattccaat
    15241 tgaattcatc tgtggaaagg gcaacaataa gataatctcc atattgtttt gctcgtttca
    15301 gtaaattgat atgcccgtag tgaagcaaat caaaggtacc gtaagtaatt actcttttca
    15361 tctttcacct ctcgaaattc attaatatac attgttagtt tagcattttt ttgttagaat
    15421 tgaaagaacc agtttatcct aaaaaggata agaaatgttt atgagaaata ggtggatgga
    15481 ggaaaaatgt tgaatgaaaa atttttaaaa tatgtgaaag gttggtattt tatttatttt
    15541 ggttttattc taatgttacg agcaataggc ccgtatttac tattacctac tagatatgat
    15601 actttacttt tttggcctgc tggaatagcg ggagttgtct tgatcattat agatgcaatt
    15661 attgcattta gagaaaaaaa tcttaaaaaa tatgattggc tattaattgc ttttattggc
    15721 gcgatgctag taagcagttt aatgaattta aaatatggat atagcgaaaa tatcaagtta
    15781 atcatgtggc aattaatctt tttctttatg atttatcagt ttggcaaaga ctacagtagt
    15841 aacttttttt tcaaagtatt tacttggata ctttcattgg tatggttttt agctaattta
    15901 gtatcattat actggtttgt cattcaatat ggcataaaaa ttccaataaa atataagtat
    15961 tacccagttc gtttagggtg gttaggcaac cgtttatttg gtgtatatac agatccaaat
    16021 tttggtgcgg ttatatcatt aattgtcatc attattgcta tatattattt ggtcacttac
    16081 aagcatttaa atcttctatt taaaatattt tttgcaatta atatttttat tcaattctcg
    16141 tttattgctt tatcgggctc acgcaccaca ttagtttgtt tattaatagc aacttttgtt
    16201 tttagtttct ttacaagtta tagtagtcgt tttcttaaaa ctaatacttt aaaaagatgg
    16261 ctaactgcat tagtagtagg attgctaagt ataattgcga tgtattatgt aacagatata
    16321 actgctcaag catgggcaca tgttccgcat attacagaaa taaaaaaaga tatatctgat
    16381 tcatcaggaa caactagcag caataaagtt gatttaaaac gccctgacac tgatggcggg
    16441 gatgtttcta atttaaggtt tggactttgg aaaagtgcaa ttgaaatatt caagagtaag
    16501 ccgatatccg gcggttctcc aggatactat attgaatacg cacatgataa actaccatat
    16561 acattaatgg gaaaagatac tttaactgct cataatttta ttttcttagt tatggctgct
    16621 acaggaggat taggtctatt gacattgtta accttcttat ttatccaatg ctttaaaact
    16681 ttgcgttatt gtttcacaca accaaatcta gtaaaagata agcacttttt tgctatttta
    16741 atgattctta caatagcagt ttcggcatta tttatcacag aactcatttt ggttagtacg
    16801 ataggttcat ttattttttg gggatatctg ggttctatcc aaaaaactat atctaaagaa
    16861 gaaggagtaa ctaattgaaa ctatttttag gtatataaag tagaaaagaa aactagttat
    16921 cccaacttca acaaatttta tagtttttac aatataaaaa tggtaaacta actttattaa
    16981 gtatgagaat gcataattgg agtgaatttg atggatacta tattgattac tggtggagct
    17041 ggttttatcg gttcaacgct agcgaattat ttgggaaaag aaaacaaaat cgtagtagtc
    17101 gacgatttat caatgggaaa aaaagaaaac ttggatatgg agaaacaagt gactttcatt
    17161 gagggggatg tatcagatcc tcaattgatg gaaagaatca tgaaacagta tcagtttgcc
    17221 tatatttttc atttagctgc tgtagctagt gtggcagatt ctgtagaacg tcctctagaa
    17281 actcatcgtg taaattttga cagtgcgctt ttattgcttg aattggtacg aaaatatcaa
    17341 tctggtttaa aacgattggt atttagttca tcagctgcag tttatggcga tgaaccaacg
    17401 ttgccaaaaa aagaagaatc ggtcatccgt cctttaacac catatgccat cgataagttt
    17461 gcatcagaac aatatgtttt ggattactgt catttatatg atgttccgac tagtgctgtc
    17521 cgatttttta acgtttatgg tccaaatcaa aatcctaact ctccatatag cggagttatt
    17581 tcgattctag tggaccgata caaaaaacaa ttggcaggag aaaaaacaga atttacttta
    17641 tttggtgatg gtagccaatc tagagacttc gtttatatag aagatgttat acaagcactt
    17701 ttacttgttg ctaaggaaga aaaagcttta ggacagcaat tcaatgtcgg tacaggaaaa
    17761 agcactacgc tacttgaatt gattcattca attgatcaaa tcttaggaac agagctagcg
    17821 cttaaatatg aagcggagcg ttcaggggat attcgtgatt ctttagcgga tatttcaaag
    17881 atccgttctt taggttatca acccaaattt gatatattga acggaatgga acgttattta
    17941 aagacagaaa tcgattgaaa caaaaaacca gcatcctgct ggtttttttg tctcgactta
    18001 gctttttaaa ttaacacctt ccatcagttc gtaaatctga tttcttaaat cagtggccgg
    18061 caatttgatg tttttatcag attggatatt actttccatg acgattgcat cttttgtgtc
    18121 ttttttcatc gccgctactg catggaatcg attgatattt ccctgagcaa ggatataatc
    18181 atttccactg taaacaccgc cgctgtaagg atgtttatca ccattatttt gccacaatga
    18241 gaaaagtagt tcttttggta taatatcgcc agacagaaca ctggtaaaga atttgttcaa
    18301 gtcataaaca gacatactta tatttcctgt gcctaattca tttcggatgt ctgtttcagg
    18361 ctcgaccaat gcttttgaat aatcgtcagt tgcagacatt tggtaagata cagcatgctg
    18421 aggggaattt tttacatttt cataaaaatc tgtatgttct agatggagtg gccgaatgat
    18481 ttcttttttt aaaagagttt cataaggctg attcattagt ttgatcaata cccctgtaag
    18541 caatgtataa tttaatggtt cataatgata cgtatcataa ccagtaaatt tcaaatgatg
    18601 aagggcaaac tgaatgatct cactatctga cataggtttt tttggagaag cggttcgatg
    18661 aagaccagag cgcatgtaaa gcatattttt gattgagatt tgctgacttc caggaatctg
    18721 aggataaaat tcagatagct ttgtgtcaaa agttatcttg ccagattgaa tttgttttag
    18781 gataagtaaa gcagtcatcg ctttttggat cgaaccgatt tgatagtaaa gagaaggaga
    18841 attcgattct tttatgcgta gatttgcgta cccatatcct ttttctaata tcactcgatt
    18901 atttttgcgt acataaatcg aaccgatata atctgatttt tgcagtaatt gatcaatttt
    18961 gctggcaagc atctgctcat tagatgttaa attggaagca agttgtgcgg gttccgtttt
    19021 ataaatttgt ggttgaggtt gttttgttaa ttgccatcct gtaatgatgc ctgttgaaaa
    19081 gaagctgaca gccagcaaca aaactgcgag aaaagaaaga gagatctgct gttttttttg
    19141 atgttttcct tttgccatat taaatccttt ctatccattt ttaactattt ttcattgtaa
    19201 tcctcaaaaa gagcatttgc cacttacaat tttgacataa tatttggtaa aataattcac
    19261 ggcagtagaa atttcatgta taataaacag agttacgaag atgatagtaa ggaggagttg
    19321 ttttgtcagg aaacaaacaa cacccaagca aagacaaaaa agaagccagt aaggcagcta
    19381 cagcagatat aatcgacaag cggagaaatc tgcgtaaaaa agaagataag atcgtgagga
    19441 agatcatttt agtgatcgct cttacattat tgattattgg cggatttctc gggtttaccg
    19501 tatatcgtta tgtagatagc gggttgaagc ctttagataa atcggacgac caattagtcc
    19561 aagtggaaat cccaaacggc tcttctaata agcagattgg cgaaattttg gagaaagaca
    19621 atattattaa aagtgggatt gttttcaatt attatacaaa atttaaaaac ttaactggct
    19681 ttcaagctgg ttattatcag ttagcgccta atatgactct tgatgagatt ggcaagcagt
    19741 tgcaagaagg cggcacatct gagccaacaa aagttgcaga tgggaaaatt gccattccag
    19801 aaggctacga catcgatcag attgctgagc gggtagcgaa ggtaacaggt aaagacaaga
    19861 aagaattttt agatttagta aatgatgaga ctttctttaa cgagttgtat caaaaattcc
    19921 cagaattgtt ggaaagtgcc tctaaagctg agaacacaaa ataccgtttg gaaggctact
    19981 tattcccagc tacttatgat tactacacga gtacttcgct taaggatctt gtgattgaga
    20041 tggtgaacaa gacaaatacg gtcatgcaaa actattattc agctatcaaa cagaaaaatt
    20101 tgactgtaca agaagtttta actttggctt ctctagttga aaaagaaggc gtaaaagaaa
    20161 atgatcgtaa aaatattgca caagtcttct ttaaccgaat caaggcaaat atgccacttc
    20221 agtcagatat ctctgtttta tatgcattag gagaacataa agaattggtg acgtatgaag
    20281 atacagctgt agattcacca tacaatttgt ataccaatac cggctatggg cctggtcctt
    20341 ttgacaatcc aagcgaaaag gcaatcaagg cagtattaga accagcagaa aatgactatt
    20401 attatttcgt agcagatacg agcactggaa atgtttattt cgctaaaacg tatgaagaac
    20461 atatggaact agtgcaaaaa tatgtaaata attcttagaa aaacaggggc tagtcattga
    20521 tcatttttag aaaaacattt acattttaag aaaagcgtgg taatcttttt tggactatat
    20581 tcctcaaaag attacctttt gcggtatttt atcgaaaaaa ggagacgtta cacatggtag
    20641 agaaagttta tccaatgact ctagaaggta aagaaaaatt agaaaaagaa ttagaagaac
    20701 taaaaacagt taaacgcgga gaaatcattg aacgaatcaa aatcgctcgc ggtttcggag
    20761 atctttccga aaactccgaa tacgaatcag ctaaagatga acaagcattt gttgaaggaa
    20821 gaatcacaac aattgaaaat atgatccgtt ttgcacaaat catcgataat gacggcgtag
    20881 atgcagatga ggtatcgatc ggtaaaacag ttacgttcat cgagttgcct gatggagatg
    20941 aagaagagta cacgattgtc ggaagtgctg aagcagaccc gttttctgga aagatttcca
    21001 atgattctcc tatcgcgcaa gcattgattg gcaaacgtaa aaatgatgaa gtaaccattg
    21061 ctacaccagg tggcgatatg ttagttaaaa tcgtcaaagt agaacaagcg tagtctgact
    21121 gaaagatcta gagagttcat cttactgatg acgcactcta gatcttttct ctttgagtat
    21181 tgcaggtttc actgaacgat cttacatcta aagtcctata gccaacagtc aaaaaaatag
    21241 gtatgatgaa atgagaatgt gtcaggaggg agaaaaagcg atgaatagtt cttggcgttt
    21301 ttttgtggta gtcgaagcac tgctgctgtt atttgctgtt tggcaaatcg taaacaatac
    21361 tggacttttg cttttagtaa tattcggtat tttcaatata tatctagcta tgcgcaaata
    21421 tcctcgtact aaatttcaaa attttcaatt gatcttaggg agcttggtca ttttttttag
    21481 cttagtcaac agtcctgctt tatggatgat ggttgtattg gccgttttat ttatcgggct
    21541 gaaaggtgta gagatttcag gaatagattt gacaaaaaat gctttttggc gaaaaaaaca
    21601 gatcatgatg gtccaaacag agcaattaaa aacacataat aatgagcgta aaagacagca
    21661 attatttggt aaccaacgta ttggaaacga cgtctatgaa tgggatgata tcaacattgc
    21721 catcatttct ggtgatacta tcatcgattt gggtaataca cttttgccaa aagatgataa
    21781 tattgtgatt gtaagaaaag ggataggcag aacacggatc ttagtacccc tgggagtggc
    21841 tattcgttta gagcatgcga cattagtagg aaatgtcttg tttgaagaag agcagttttc
    21901 cttaaaaaac gaacagatca aaatctgcag cagtgattat gatgaaaatc ctcgcagatt
    21961 gaagatcatt accaatacct tggttggaga tgtcgaggtg atacgaatat gatgggaaga
    22021 atatccaaag caatgctagc tgtttattcg gggattgcgg ctttccttat tattctattt
    22081 tcacttttca cttattttta tgccagtaac caaagtcatt ggtggggaga attgctgcgt
    22141 gcgcgtttat tatacgttcc gcttatcttc catttgatgg caatttcatt aggtgtagga
    22201 ttgatcgtat ttctattgtt atcacttatt caaaaggcaa aatacgggaa aatcgaagaa
    22261 aagcttcgtg cactttcttc tggcaattat gaatccaaac ttttgcatca gccgatccca
    22321 agcgcgtcgg atgatctgta catcaaagat attgatatgg aaattgctaa aataaaagaa
    22381 aaaatgatcg aagtatccag tgaattacag attatgacta gccgtcctca atatgtagat
    22441 ggacaaacca aagaagagat tttagaatta gaaaggcatc gattagctcg tgagcttcat
    22501 gattcagttt cacagcaatt atttgcagcg atgatgatga tgtcggcatt gacggagcaa
    22561 gcagaaaaaa gtgagacacc agaaatgttc cgtaagcagt tgaaaatggt ggcagagatc
    22621 atcaacgctt cccagtctga gatgcgtgcg ctgcttcttc atctgcgtcc agtcaattta
    22681 gaagaaaaaa gtttaaaaca aggcattgag cagttattga aggaattgca gaataaaatc
    22741 cagatttcgc taaaatggga tgtagaagat gtaaaattaa ctagttccat tgaggatcac
    22801 ttgttccgaa tcgttcaaga attgttatca aacacattaa gacatgctaa ggctaatgaa
    22861 ttagaagtct atttgcataa aatagataac aatcttttat tacgtatcat tgacgacggg
    22921 acaggattta atatgaatga aaccaaaacg ggaagttatg gattgaacaa tatcaaagaa
    22981 cgagtagctg gtattggtgg aacagtaaaa atcattagtt ttaaagggca aggtacgagc
    23041 gtggagatca aggtcccttt gatgaaggag gcatagataa agatgataaa agttttatta
    23101 gtagatgacc atgaaatggt acgcttaggc gtctcttctt atttatctat ccaagaagac
    23161 attgaagtga ttggagaagc tgaaaatgga cgtcaaggct atgaaaaggc gatggcactt
    23221 cgaccagatg tcattttaat ggatctagtc atggaagaaa tggatggcat cgaatcaaca
    23281 aaagcaatct taaaagattg tccaaaagcc aaaatcatta tcgtcacaag ttttattgat
    23341 gatgaaaaag tttatcctgc aattgaagca ggagcagcag gatatttgtt gaagacgtct
    23401 accgcacatg aaatagctga tgctataagg gctacgcaac gcggcgagcg agtattggaa
    23461 cctgaagtga caacaaaaat gatggaaaaa atgagtcggc gaaatgatcc agtattgcat
    23521 gaagaattaa cgaatcgaga aaatgaaatt ttgatgctga tttctgaagg gaaaagtaat
    23581 caggaaatcg cggatgaatt gtttatcaca ctgaaaacag ttaaaacgca tgtgtcgaat
    23641 atattagcta agttagaggt agaagaccga actcaagcag ctatctatgc gtttaaacat
    23701 ggtttggtga aataaaaacg atgataaaga ggataatcaa aagctgagaa aataactatt
    23761 atttttcttg gcttttttac aataatgatg cttgcttttg tttttggaaa ggctttgtta
    23821 tactgagaaa agaagatact aaaggaggaa aatggtgaaa caaaattttg caattgtagg
    23881 ccttggacga tttggcggaa gcatctgccg tacactgatc gaagctggac aagaagtact
    23941 ggctattgac agtaatgaag atcgagtcaa tgaatatatg aatatagcca ctcatgctgt
    24001 tgtggcaaat gcacaggatg agatgacact tcgttcatta ggtataagaa atttcgatca
    24061 tgtaattgtc gctattggag aagatatcca agccagtatc ttagttactc tgatggtaaa
    24121 ggaaatgggc gtaccgaata ttttagcaaa agcccaaaat gagtaccatg cccgtgtact
    24181 agagaagatc ggagcagatc gtgtcgtaca ccctgagcga gacatgggga tacggattgc
    24241 acataactta gtatcaaaga atattctaga ctacttagag ctgtcagata aatattcttt
    24301 agcagaaatc cgagtctcca atcctaaatt tttcaacaaa acattagctg aattaaattt
    24361 caggcaacgt tttgacttaa cagtagtcgc catacgaaga gtagatcaaa cggttatcgc
    24421 ttctcctgca gcagatgaat atgttcgcga aaatgataat ctactggtga ttggagagac
    24481 aggcgatgtg gatattctag acgataagat gaatcaatag aaagaaaaga gaaagtaggt
    24541 tgttgggatg gaattaacgg taacgccaaa agcacaaaag tggtttgact cagaaattga
    24601 tctgccagaa acttacggaa tacgtttttt tggaaaagtc tacggcaaaa cagaggttca
    24661 tgatggtttt tcgattggaa tgtcagttga acagccagaa catcctgtaa agaaagtgga
    24721 aatggatggg acactttttt ttatcgagga agcagatgaa tggttcttta aaggatatga
    24781 tttacttgtt gattatgatc ccaacctgga ggagccaacc tatcacttta aaaaacaata
    24841 aaaaaagaga gggtgacaca agtttt
//
LOCUS       DAKCAA010000038        24271 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000038 DAKCAA010000000
VERSION     DAKCAA010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.038"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..572
                     /locus_tag="OUE31_001698"
     CDS             <1..572
                     /locus_tag="OUE31_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCU0222708.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="OUE31_001699"
     CDS             576..1217
                     /locus_tag="OUE31_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222709.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="OUE31_001700"
     CDS             1214..2131
                     /locus_tag="OUE31_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HCU0222710.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="OUE31_001701"
     CDS             2128..2799
                     /locus_tag="OUE31_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222711.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="OUE31_001702"
     CDS             complement(3340..3828)
                     /locus_tag="OUE31_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HCU0222712.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="OUE31_001703"
     CDS             complement(4029..4295)
                     /locus_tag="OUE31_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCU0222713.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="OUE31_001704"
     CDS             complement(4295..4558)
                     /locus_tag="OUE31_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCU0222714.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5034..5219
                     /locus_tag="OUE31_001705"
     CDS             5034..5219
                     /locus_tag="OUE31_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCU0222715.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5361..7184)
                     /locus_tag="OUE31_001706"
     CDS             complement(5361..7184)
                     /locus_tag="OUE31_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HCU0222716.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="OUE31_001707"
     CDS             complement(7782..10487)
                     /locus_tag="OUE31_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HCU0222717.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="OUE31_001708"
     CDS             complement(10793..11740)
                     /locus_tag="OUE31_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HCU0222718.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="OUE31_001709"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="OUE31_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCU0222719.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="OUE31_001710"
     CDS             complement(12375..12737)
                     /locus_tag="OUE31_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCU0222720.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /locus_tag="OUE31_001711"
     CDS             complement(12748..13869)
                     /locus_tag="OUE31_001711"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCU0222721.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /locus_tag="OUE31_001712"
     CDS             complement(13885..14235)
                     /locus_tag="OUE31_001712"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HCU0222722.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="OUE31_001713"
     CDS             complement(14365..15876)
                     /locus_tag="OUE31_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCU0222723.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /locus_tag="OUE31_001714"
     CDS             complement(16198..17550)
                     /locus_tag="OUE31_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HCU0222724.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="OUE31_001715"
     CDS             complement(17703..18779)
                     /locus_tag="OUE31_001715"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCU0222725.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="OUE31_001716"
     CDS             18975..20720
                     /locus_tag="OUE31_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HCU0222726.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="OUE31_001717"
     CDS             complement(21000..21437)
                     /locus_tag="OUE31_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HCU0222727.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="OUE31_001718"
     CDS             complement(21421..22794)
                     /locus_tag="OUE31_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222728.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="OUE31_001719"
     CDS             complement(23116..23604)
                     /locus_tag="OUE31_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0222729.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="OUE31_001720"
                     /pseudo
     CDS             complement(23626..24228)
                     /locus_tag="OUE31_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
BASE COUNT         6959 a         5163 c         4488 g         7661 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agctcaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgtc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcgt aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctg caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaggagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaatagcc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa gcttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc atggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgcta gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc t
//
LOCUS       DAKCAA010000039        23827 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000039 DAKCAA010000000
VERSION     DAKCAA010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.039"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(53..787)
                     /locus_tag="OUE31_001721"
     CDS             complement(53..787)
                     /locus_tag="OUE31_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCU0222730.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1526
                     /locus_tag="OUE31_001722"
                     /pseudo
     CDS             1114..1526
                     /locus_tag="OUE31_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
     gene            1519..2220
                     /locus_tag="OUE31_001723"
     CDS             1519..2220
                     /locus_tag="OUE31_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HCU0222731.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2220..3806
                     /locus_tag="OUE31_001724"
     CDS             2220..3806
                     /locus_tag="OUE31_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222732.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3825..4046
                     /locus_tag="OUE31_001725"
     CDS             3825..4046
                     /locus_tag="OUE31_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HCU0222733.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4043..4804
                     /locus_tag="OUE31_001726"
     CDS             4043..4804
                     /locus_tag="OUE31_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HCU0222734.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5184..5693
                     /locus_tag="OUE31_001727"
     CDS             5184..5693
                     /locus_tag="OUE31_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCU0222735.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5768..6307)
                     /locus_tag="OUE31_001728"
     CDS             complement(5768..6307)
                     /locus_tag="OUE31_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HCU0222736.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="OUE31_001729"
     CDS             complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="OUE31_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HCU0222737.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7320..8171
                     /locus_tag="OUE31_001730"
     CDS             7320..8171
                     /locus_tag="OUE31_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCU0222738.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8199..8834
                     /locus_tag="OUE31_001731"
     CDS             8199..8834
                     /locus_tag="OUE31_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HCU0222739.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8854..9627
                     /locus_tag="OUE31_001732"
     CDS             8854..9627
                     /locus_tag="OUE31_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCU0222740.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10035..10832
                     /locus_tag="OUE31_001733"
     CDS             10035..10832
                     /locus_tag="OUE31_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HCU0222741.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10810..11223
                     /locus_tag="OUE31_001734"
     CDS             10810..11223
                     /locus_tag="OUE31_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCU0222742.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11207..13852
                     /gene="mutS"
                     /locus_tag="OUE31_001735"
     CDS             11207..13852
                     /gene="mutS"
                     /locus_tag="OUE31_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCU0222743.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13870..15978
                     /gene="mutL"
                     /locus_tag="OUE31_001736"
     CDS             13870..15978
                     /gene="mutL"
                     /locus_tag="OUE31_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HCU0222744.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16000..16560
                     /gene="maf"
                     /locus_tag="OUE31_001737"
     CDS             16000..16560
                     /gene="maf"
                     /locus_tag="OUE31_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCU0222745.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16645..18633)
                     /gene="treP"
                     /locus_tag="OUE31_001738"
     CDS             complement(16645..18633)
                     /gene="treP"
                     /locus_tag="OUE31_001738"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HCU0222746.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18856..19569
                     /gene="treR"
                     /locus_tag="OUE31_001739"
     CDS             18856..19569
                     /gene="treR"
                     /locus_tag="OUE31_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HCU0222747.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19646..20092
                     /gene="msrB"
                     /locus_tag="OUE31_001740"
     CDS             19646..20092
                     /gene="msrB"
                     /locus_tag="OUE31_001740"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HCU0222748.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20262..20864
                     /gene="ruvA"
                     /locus_tag="OUE31_001741"
     CDS             20262..20864
                     /gene="ruvA"
                     /locus_tag="OUE31_001741"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HCU0222749.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20877..21878
                     /gene="ruvB"
                     /locus_tag="OUE31_001742"
     CDS             20877..21878
                     /gene="ruvB"
                     /locus_tag="OUE31_001742"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HCU0222750.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21907..22485
                     /locus_tag="OUE31_001743"
     CDS             21907..22485
                     /locus_tag="OUE31_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCU0222751.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22537..23019
                     /locus_tag="OUE31_001744"
     CDS             22537..23019
                     /locus_tag="OUE31_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HCU0222752.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23136..23510
                     /locus_tag="OUE31_001745"
     CDS             23136..23510
                     /locus_tag="OUE31_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222753.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4285 c         5117 g         6644 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg
     1501 aaatggagga gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg
     1561 actttaggag tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg
     1621 aatcctctcg tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc
     1681 tataaagact ataatatcgg gggcaatttt ttgactatgc tgattactcc tgcgacagtg
     1741 gcacttgcca tccctcttta taaaaacttc cgtttactga aagagaattt ttatcctgta
     1801 atggctgcga ttttagcagg aatagtcgca aattgcttgg ttagtgtagg gttcggttac
     1861 ttcttctctc ttcataaaga gatggtgatc tcattactac ctaaatctgt aacgacggct
     1921 atttctgtcg atttatctca tacgatgggc ggggtgaatg ccgtgacact tgctattgtt
     1981 gtctctacag gtatttttgg ttcgctgatc gccactcata ttttccgcct attcaagatc
     2041 gaaagtccag ttgctcgcgg tgtggcgtta ggaagtactt ctcatgctat tggtacagca
     2101 aaagcaatcg agattggtga aatagaagga atcatttccg gacttgcgat atgcgtcaac
     2161 ggaatattga ccgttttatt gctaccgtta ttctttcagc cttttgctgg cttgttttga
     2221 tgcgaaaacc actattttat gctacaataa ccaaaacgtt cgagcataaa aaaggaggga
     2281 aagacgtgta tttgtcttcc gagtatctta aacaatttga taaagatcta tattataaga
     2341 ttctcctcct agaaagtttt gaggatcaag cttggcatac cgctgcacaa ttagcgcaag
     2401 ttgttcagct ggatgcccgc agcgtgtcga aatacctgaa cgagctgtct aaaaactatc
     2461 agcagtttag cggtaagaca caccctttgt ttacaaaaaa tcaccgttct ggttataact
     2521 tttatgatac gctcgattca attgaacatg agcgtttttt gatctatctc gtgcaaagta
     2581 cgctgaaatt ccagttgctg cacgacattt tttttgaaga attccataca atgtaccaat
     2641 ttgcgcaaaa gcattacatt agtgaatcta ctgctcatcg aaaaatcaat gaatggaaac
     2701 agcaactgca aacttacgga attcggctgc aacgaggtac atatatcgct caaggcgaag
     2761 aagaaatcat tcgactttac ttgcatatga cattctggca gttgtttcga gggaaaatct
     2821 ggccatttga aacgatttct caaatggacg taaagaatat ggcagaacat atcatggctt
     2881 tttttaatgt tcgtctgaac gagatcaaaa aaagacgatt ggaatatatg ctaggtgcct
     2941 tttttttaag aaaatcacag aagcattatg ttgtattgaa tgagaaaaaa agacggctga
     3001 tttctgacaa tctgttgttc cagcgatttt gccaggtcat ggagccggta tttcctaatt
     3061 attttcaagt agaagacgag ttaggcgcat tatttcttgt actgatgact cgtgaagaat
     3121 attatagtga tcctaagata cggaagaaaa tttttgattt tcatcaacaa gcaaaaacac
     3181 cgccctttac agccctttca gaagcaaaag ccgctctttc tctttatcag gaagagcagg
     3241 ggctgccagc agaaaatcta accttcgagg cagaaaacta tttattcagc agtcattttt
     3301 tcgcctatct ttttcctaat gcgaaagaaa cgattgatgg caatagtagt gattttatta
     3361 atcatttagt tattgaaaac aaggaattga aacaatggct cgtacatttt tttgaaagta
     3421 gacacaaaca tcccaatcat ctggcattta aaaatcatgc gtttttgatg gggcggtatc
     3481 tgactgtgtt taaaacatta ggagccttta ctccacagct tccaaagatc acgatccttt
     3541 taatgacaga tttcccatta tttgaagagc aactgttaga ggagggatta cggacatttt
     3601 tccgtaatga gtatcagctg atttttctgc caacagatta tcgggggaga gaagttgatc
     3661 ttctgatttc gacaagtaaa gtccaccgca aaccatgggc ggatcttgac tattttattg
     3721 tgactgaaga actaaaatta attgattaca tccaactatc tcaaaaattt gaaatgattc
     3781 aaaaacaaaa actattaaaa caataacaaa gaaggagaaa aaagatgaca tttgaagaaa
     3841 ttttaccaga attgaaaaaa ggtgcaaaga ttattcgtaa aggatggagt ggatttgaac
     3901 tttatgttgt tctcgtatcc gatgatgaat ttgatggctg tccggtgacg ccgtacttat
     3961 tgatcaaaac aagtgacgaa ggtttttcca gcttcgctcc tacagtttgt gatattttag
     4021 cagatgattg ggcgatcgta gaatgaaaaa ccagtatcca gatctagcta aacaggttgt
     4081 atttatcaca ggagctgctt ctggaattgg tgctgcgcaa gcccgagcgt ttcttgaaca
     4141 agatgctttt gtatttggat tagatcaaaa gttcggtaaa atggaagaaa tttctttgcg
     4201 atttcctgaa acttttgcct acgcactagg tgatgttcga caaatgaaag aactccaaca
     4261 agcggtatcg aaatgccaaa atcattttgg tgaagttacg attttactga atacagcggg
     4321 gatattggat gcctacaaac ccttgatgga aactgacgaa tcgctgtggg atctgattta
     4381 tgagacgaat gtgaaaagca tgtatcagct gacaaaaatc atccttcctg atatgatccg
     4441 ccaaaaaagc ggaacgatca tcaatatggc ttcgattgct ggcttgattg ctggtggagg
     4501 tgggatcgct tatacaagcg cgaaacatgc gattgtcgga tttaccaaac aactcgctct
     4561 ggattacgca ggacagggta tccgagtaaa aggaattgct ccaggagcca tccaaacacc
     4621 aatgaatgcg gctgattttg aagggaaagg tgagatggca gagtgggtgg caaatgaaac
     4681 accagtcaag cgatgggcac agccggaaga agtagctgag ctgacgttat ttcttgcctc
     4741 tcctcaagca agctacatac aaggaacgat catcccaatc gacggcggat ggttgttaaa
     4801 ataaccttgt gtttttttca agcttctgta tgataaaact aaagagagaa acaacggttg
     4861 atgataaaaa aagtcgatga ctgttcccga cattcgatgc cgaacagcca gttcaaaaaa
     4921 ttctttttaa taatcgttaa tattcgaaac taagcggctt ttcacgacct cttgatataa
     4981 acgatattca aaagcttgca actgcggtaa caagtccagc caaatgaaaa atataaggag
     5041 ctatttttat ttgaccattc ttattacttg ttgcagggca gctttttcac taccttctgc
     5101 gacacttcag ttggaatttt cttcccatcc tttggtcgcg gtcattacca agataaaatt
     5161 atcttgcaaa ggagaaatag aacatggaaa aaaataatac ccgttcagcc aaacgctgga
     5221 caacgacaga tgtgactcgg atggcgctag tcactggttt atatgtggca gtgacgctgg
     5281 ttttgtctgt ctttagcttt ggagtgattc agattcgtct ctcggagatg ttcaactatc
     5341 tgtccttgta taacaaaaga tacatcgtcg cggtaacagc gggagtagct ttggctaata
     5401 ttgcttctcc tcttggactg atagatgttg cagtaggaag cgtcagcacg ctgcttgtat
     5461 tgcttatcaa ctataaaatc actagtcgca tcaaaaacat gaaaatcaaa atggccgtga
     5521 cagcatgcgt atttgctttt tccatgttta cagtagctgg tcagctaacg attttatatc
     5581 aactaccttt tttcttgaat tggtgggtga ttgctttagg agaattggca tcaatgattg
     5641 tcggtgggat aattatttat tggatcggta aaaaagtgga tttgtcaaaa taaagatctg
     5701 tttaatttaa aatagggcag catggaagag actgaatgtt gagtcttctt ccatgctgct
     5761 tttttgatta atttgtatga agaaatcgat ttagccgttt tttcatcaag ataccgatat
     5821 aagctgctcc agttgccttg attgcttccg gcagtaaaaa cggcagtagt ccactggcaa
     5881 atgcagttgt aaaagtaaga tcaccactta ttttcagcca gatcgttccg cagatcaatg
     5941 cagcaagaga gcccattaga ttggcaaaga ttgcatataa gtaatgagca tccgttcttt
     6001 cgatcatcca accagttatc cacgtttgta agagaaatcc aatcaaatat ccgccagttg
     6061 gcccaaataa aacagctata cctccagtca tccctgaaaa tacaggaaga ccaatcaagc
     6121 caagtaaaag ataaactcca acagatatca atcctagttt tcttccgaga aaagttgctg
     6181 ttaatccaat agcaaatgtt tgccctgtca aaggaaccaa accaaaagga atggtcatct
     6241 gagaaaggac agaaataatc gcggcaaatt ccgcagcaag tatcaattct ttcaatgttc
     6301 ggttcataac gccctctttt cgttaactta atatttttat ttggttaacg aaattgtaaa
     6361 acaaagtgat tactttgtaa atagaaaata taaaaaaaga ccagctatcc aatagatagc
     6421 ggtctttttc aagaaagctt ttgaaattat aagctttggt tgtagtattc aacgacaaga
     6481 gcttcgtcga tttctggata tagttcgtca cgttctggta aacgagtcaa tgaaccttcc
     6541 aatttttcag cgtcaaagct tacgaatgct gggcgtccaa cagttgcttc tacagcttct
     6601 tttactgtta cgatgttttg tgatttttca cgaactgaga tcacttgacc cacttctacg
     6661 tggtatgaag ggatatcaac gcgtttgcca tcaactaaaa tgtgaccatg gttaactaat
     6721 tgacgtgctt gacgacgagt cgttgcaagt cctaaacggt aaacaacatt gtctaaacgt
     6781 tgttctagta agatcatgaa gttaacacca tgtttacctt ctttgatttt gctagctttt
     6841 acgaacaagt tacggaattg acgttcgttc attccgtaca tgtgacgaag tttttgtttt
     6901 tcagttaatt gcatgccgta ttctgattgt ttgccacggc tattaggtcc atgttgacct
     6961 ggtgcgtaag ggcgacgtgc taattctttt cctgtgcctg acaatgagat gcctaagcga
     7021 cgagaaattt tccatgatgg tcctgtataa cgagacatta aaatttcctc caatgaatat
     7081 aagtttttgg agtaaaataa tccgttgaaa aattcataat catatagttt gttcttcaat
     7141 cttcaccttt gcagccgcgg ttacacaatc gaacccgaga cggggcaaca aactagggat
     7201 gagttattat ttttctgctg cattatttta cacaaattac agtatatgat agatcatcca
     7261 cgaatgtcaa gataattagt acataaaaac gctttacaaa cctaggctgt ctttataaaa
     7321 tgagagggta tgtgcaaatg gaaaaaagcg aaggaagttt aaggagaaaa tcaatgaatc
     7381 cggtatcacc attatttgag aaaatcgatg cttcaattga aaagaaggcg aatctttttg
     7441 aaaacagctt ttcacgttac gctgttcgag cggttctcgc ctgtttgttt ttgactttag
     7501 gaacggctgt ggcatttgcg atcgcgatga agggggaaga tatcgcgcat ggtctaggaa
     7561 agattttata cgcatttatg ttcagctggg gtctggtcat gattctatac atgaacgccg
     7621 aattaggaac atcgaatatg ctttatatga ccgtgggtgt ttttcggcag agacttgctt
     7681 taagtaaggc agccaagatt ctatttgcct gtattttttt caatatgatt ggcggtatat
     7741 tatgtggatt tctaatttct atgactacgc catttcaaga tttaacgttg gacaacttta
     7801 tgttagaatc aatagcagta aaactagcaa aaccttcagc aacgattttg gtggaaggga
     7861 tgtttgcgaa tatcgttgtc aataccgctg tactgatcag catgcggatg aaagaggatg
     7921 tcggaaaagt gatcacagtc gtattcatca ttttcatttt tgctttttta ggatatgaac
     7981 acgtgatagc gaattttcct gcctttacgc ttacttactt tgcttctcac ggacagatgg
     8041 atggaatgac agtcagcaat gtgttacata atttgttttt tgctttggca ggaaattata
     8101 ttggtggcgg tttagtaatg ggactgggat atgcttggct gaatcagtca aaatcatcct
     8161 atgtggacta aaaagtcgtt cattaaaggg gaagtgccat ggaagtttta gtttttccaa
     8221 aaaatgagga aaaagcgtta caaatggaaa agtacatgaa aaatcttttt tcctttgctg
     8281 gagtacctaa gccggaacgc gctcttttac aacaaccgtt actggatgag agcaaaaatt
     8341 tatctatttc tgaagtttta gcttttgttc attattatta tgaacaaatc gaaagagagt
     8401 atcagtatgt agcgatcgat ttagtccaga aaaacatcaa acggcttaca tttgaagact
     8461 tagtcgtatt gttgccacta gttcagaaaa aagaatggtg ggacagcatc gactcttgga
     8521 gaaaagtata cagcacatgg tgtaaagcct acccagagca gcgtgaagaa gtctttcaat
     8581 tgtttgaaaa aaaggaagat ttttggctac gtcgaatagc aatcacgttg caattaggtt
     8641 ataaacagca aacagacaca ggactattga tccgagcaat agacgaagat cgtcaaacaa
     8701 aggaattctt tatccaaaaa gcaattggtt gggcattacg cgattatagt aagaccgatg
     8761 ccgattgggt aaaaagacag ctgacaacag atttgagtaa gttagctgtt cgagaggcaa
     8821 gtaagtattt ataagaaagc gagacgacaa gagatgagac gcaaattatt tgcttttgat
     8881 attgatggaa cgttgttaga ttcaaacaaa caagctttag atagcacaag agaagcattg
     8941 gaaaaattac gcaaagccgg tcatctggtc acgattgcta cagggcggag ccgatttcat
     9001 gcgcaagaga tcattcgcga tcttgatttt acgaactaca ttttatgtaa tggagcggcc
     9061 ggttttttag accatgaaca agtatataag aatttactag atcgcgacca gttggatgcg
     9121 ttcgttcaag aagcgcatca tgagcagatc gatacagctt ttgtcagctt agacaatatc
     9181 aagcgttctt cttccaatga tgtaacggtg atggaagaag cgatgcattc tttcggtgct
     9241 gtcttgcctg aattagatca gttttttgca gaggaacaag aaatatacca agcgttagca
     9301 tttttcgatc aaacatatga tgggaagttc tcttcatatg ataaaattcg atttgtccgc
     9361 tggcatgaga acagtgtaga tgtcgtacct aaaaatggtt ctaaagcagc gacaattctg
     9421 cacttagcag aacaagtagg catccctcat gaagacatca tcagctttgg cgatggacaa
     9481 aacgaccgtg aaatgttgcg catgtcagga attgggatag ctatggggaa tgctgtgcca
     9541 gaagtacaag cagaagctaa gatggtcact gatacaaacg atcaggatgg aatttggaag
     9601 gcattgaaag agttaagcgt gatttaaaag aggttgtgaa aaagctgttc tgcatcaagt
     9661 aataagccca gccaaacaaa aatagctcct cctatttttc gtttttctgg gcttattacc
     9721 gcagatgcaa gctttcgaac accgtttaag gaagaggtcg tgacagaagt ggtcagtttc
     9781 aagaaataag aagggattta cgaaaattgc ttctcaaatt tttgtaaaat tacggcttat
     9841 ttctgaagaa gtagatgaaa caacgtttat tcgggaaatg ggactgtgac aagatgtttg
     9901 tcatagtccc atttttttat tttatttttc aaaactaaga aataccagga aagagttcct
     9961 tttgtttgac cttttctttc ttattgaaaa caactataat atagagtgat gttaaaagag
    10021 aagaggaatt tagtgtgcgg gtattgttta ttggtgatgt agtaggttca atgggacgag
    10081 agatgattac tgaatatctt cctagattga agaagaagta ccgtccgcaa gtaacgattg
    10141 taaatggtga gaatgccgct tctggacgtg gaatcacaga aaaaatctat aaaaaatttt
    10201 tgcaagacgg cgtagatgtc gtgacgatgg ggaatcatac gtgggacaac cgcggaatct
    10261 ttgagtttgt aaatgaagct aaaaagatgg ttcgtccggc aaattttccg gaagggacgc
    10321 ctggacaagg gatggtcttt gtcaaagtga accaagtcga actggcagtg atcaacatgc
    10381 aggctcgttc ttttatggtg gacttggatg atccttttcg taaaatgaat gagctggtag
    10441 aagaagccag aaaacgtacg ccgatcattt ttgtagattt tcatggagaa acaacaagtg
    10501 aaaaacaagc aatgggctgg tttttagatg ggaaagtttc agcagtggtc ggtacacata
    10561 cacacgttca gacaaatgat gcgcgaattt tgccaagagg aacagcgtat ctgacagacg
    10621 ttgggatgac aggtccctat gatggtattt tgggtatgcg cagagaacct gtaatcgaaa
    10681 agtttctgac tgcattacca aaacgttttg aagttgtgga acaaggccga tcgattttaa
    10741 gcggctgtat cttggaattg gatgatacga caggtcatgc aaaagaaatc cagctgattc
    10801 agatcaacga tgatcgaccg ttcatggagt agaaagagag gcagtttttt gcagcaggag
    10861 ccggaaattc aaaaagaagt aaggaaactg acaaaacttt taagagagaa tgaaacgatc
    10921 attcgctaca aagaacttga agaaaagatc cagcaaaacc agtatttagc tgagttgaga
    10981 gaaaaaatca aacaagcgca aaaagatgct gttcattttg cccactatga caaaccagca
    11041 gcagaaaaag aagcaatcaa acaagcggat caattcatgc aagaatttga tcagcatccg
    11101 cttgttgtag cttatagaaa acagctgttg gaagcagatg atctgcttca tcatttaaca
    11161 actatgatac aagaagaaat caatggacaa atagaggagg aaaaacatgc ctcaaaaaac
    11221 taaaaatact cctatgatgg aacaatatct aagcatcaag gcccaatacc aagatgcttt
    11281 tttgttctat cgtttaggag acttttatga actattttac gaagatgcga tcaaagcgtc
    11341 acagcttttg gaattaacgt tgacgagcag aaatcgaaat gcagaagaac ctattcctat
    11401 gtgcggtgta cctcaccatg cagcacaagg atatatcgat gccttgattg aaaaaggcta
    11461 taaagtagcg atttgcgagc aggtagaaga tccaaagacg actaaaggga tggtcaagcg
    11521 cgaagtgatc cagctagtca ctcctggtac agtcatggac agcaaaggat tgtcggcaaa
    11581 agacaacaat tttttaacag ctgtagttag tcaaggaaat gaatttggct ttgcttatgc
    11641 cgatttaagt acgggagaat tgaagacggc tcggttgcat gatgaagaag ctgttttaaa
    11701 tgaagcctct gcattgcaga caaaagaact cgtattaggc agtgagatca ctgataccct
    11761 tcgtgaacag ctaagcgggc gtttagggct agtcttttct caacaaaatg agatggaaga
    11821 aaacgcggaa tttagctttt tgacaagcga actagtcgat ccgctggaaa aagaagcaac
    11881 cggcaaacta ttgacttatt tatcggtgac acaaaagcgg agtttagctc atatccaaaa
    11941 agcagtagaa taccaaccag atcatttttt gaaaatggat tattattcaa aattcaacct
    12001 agaattaagc caatctattc ggactgggaa aaagcacggc actcttctat ggttgttaga
    12061 tgaaacaaaa acagcaatgg gtggccgttt actaaaacaa tggctagacc gtccgcttat
    12121 ccaggcaaaa caaattaaag caagacaaga aatggtcgct tctttgctag acagctattt
    12181 tgaacgtatc gatttgcagt cagcattaac gaaagtctat gatctggaac gcctagcagg
    12241 tcgagtagct ttcggtaatg tcaatgggcg agacttgatc cagctgaaaa cttctttaga
    12301 acaagtgcca atgatcagag ggttgattga aggaatcgat caaggtcaat ggcaaagtct
    12361 gctttcagaa atgcagccga tggaccatct cgtccaattg atcgaccaag ctatccaaga
    12421 tgatccgccg ttacaaataa cggaaggaaa catcatcaaa gatggattca atgagcagct
    12481 cgatatgtac cgttctgcta tgagaaacgg aaagaaatgg ttggcagaac ttgaagcaaa
    12541 agagcgtcaa gaaacaggaa tcaagaactt aaaaatcgga tttaaccgcg ttttcggtta
    12601 ttatatagaa attacaaaag caaatcttgg aaatgcagaa ctggagaagt atgaacgaaa
    12661 acaaacttta gcaaatgcag agcgtttcat cacaccagaa ctaaaagaat tggagacaca
    12721 aatcctcgaa gcagaagaaa aatctgttga tttagaatat cagttgtttt tagctgtgag
    12781 agaagaagtc aaaaaggcta tccagccgct acaagtactt gcaaaagcaa tcagtgcagt
    12841 agatgtgcta caaagttttg caacgatcag cgaacgctat cagtatgttc ggccagaact
    12901 tgtcagtgac aagcatcagc ttctgatcaa agacggacga catcctgtag tagaaaaagt
    12961 attaggacat caggaatata tccctaacag cgtagaaatg gcagaagacg aaatgatctt
    13021 gctgattaca ggaccgaata tgtctggtaa aagtacgtat atgcgacagt tggcattaac
    13081 tgttctgatg gcgcaaatgg gctgtttcgt tccggcaaaa caagcagttt tacctatttt
    13141 tgatcggatt tttacccgaa ttggtgcaag tgacgactta attgctggac aaagtacttt
    13201 tatggtagag atgatggaag ccaatcaagc cctgcgttat gctacgccaa acagtttgat
    13261 tttgtttgac gaactagggc gaggaacagc aacctatgac ggaatggcgt tggcccaagc
    13321 aatcatcgaa tatatccatc gtcatgtaca agcaaaaaca ctcttttcta ctcattatca
    13381 tgaactgacg gtacttgaga aagaacttcc gcagcttaaa aatgtccatg ttggagccgt
    13441 tgaaaaagac ggagaagttg tcttcttgca taaaatgatg gatggacctg cggataaaag
    13501 ctacggcata catgtggcaa agatcgcagg attgccttcc aatctactag aacgagcagc
    13561 agatatcctg catacgctag aaaatggcga taacggacac catactgttc cagctgaagt
    13621 agaagagaaa actaaaacag ccaaacagga gcaaataaaa ccacctgcag aaaaagtaaa
    13681 tcaagaccat atacaagacc gtgtaaaaga agaaaaccaa cagctttctt tattcagtga
    13741 attatccgaa aatgaaacag aagtcattga atcactgaag caaataaatt tactagaaat
    13801 gacgccaatg gatgcactaa acacattata tgaattacaa aaacaactgt aggaagaagg
    13861 cggatatcga tggccaaaat ccaagaatta tctgaacgtt tagctaatca gatcgctgcg
    13921 ggagaagtag tggagcgacc agcttccgtt gtgaaagaat tagtggaaaa tgcaattgac
    13981 gccggcagta ctcagattga tatcttagtt gaagaagcgg gactgcggac gatccaagtg
    14041 attgataacg gagaaggcat tttggcagac gacgtagaga atgccttcaa gcggcatgcg
    14101 acaagtaaga tccataatcg cgacgatctt tttcgcatac gaacgctggg ctttcgaggg
    14161 gaagctttgc caagtattgc ctctgtttct gaaatgactc tggaaacggc gaatcaggaa
    14221 gaaaaacaag gcacctatct gtcgctgaaa ggcggagaag ttattgagca tcgaccagca
    14281 ccactgcgtc aaggaacgaa gattaccgtc agcaatctgt ttttcaatac gccagcccgc
    14341 ttgaaatacg tgaaaacact gcacacagaa ttagcgaaca tcggggacat cgtcaatcga
    14401 ctggcattga gtcatccatc gattgctttt cgtttagtac atgatggaaa caaaatgctg
    14461 gcaactgctg gaaatggcga tctgaaacaa acaattgcgg gaatctacgg attatctacc
    14521 gcaaaaaaaa tgctgaaaat cgaaggaaaa gatctagatt ttgagttatt tggctatgtt
    14581 tcattgcctg aggtgactcg tgccagtagg aattacttat cgacgatcat caatggacgt
    14641 tttatcaaga acttttcctt gaataaagca atcgttgcag gttatgggtc aaaattaatg
    14701 gtcggtcgtt tccctattgc tgtattggaa atcaaaatgg acccgctttt agtagatgta
    14761 aatgttcatc cgacgaagca ggaagtccgg ctgtcgaagg aaaaagaact aacagagcta
    14821 attagtaacg ccattcaaaa agcattgtct caagaaaatc tgattccaag tgcagcggat
    14881 aatctacggt ttaagaaaaa agtacctgat cagcctaaaa cagaacaaat cgaaatcgat
    14941 ttgtcctacg cttttgaaga agaaaaacct aaaaagccaa gtagtttgaa ttttgatcga
    15001 gagacaggta cctttttcgt agaagaacta aagaacacat ttgttgacag aattgttgat
    15061 aagtctgtgg aaaatgttga aaactattct ggtttttctg aagaaaacac cacttatcca
    15121 gaaaaaacag cgaaaacggt ggataagttt ggtgaaaatg ttgataactt tgtagaaaaa
    15181 acagtggaaa aatctgaaaa gaaagaattt cccattgtgg ataacatgga gaaaacaaat
    15241 gaagaacaag cagataaatc cgtagaagag gatgaaaaga tttacgagga agaattgaca
    15301 ctccatcctg aatttgattt cactcaagga aacgacaaaa cattagaaca agccatcaag
    15361 aaattagaaa cggaaaaacc agtacaacgt tttcctcagt tggaatattt tggacagatg
    15421 cacggaacgt atctttttgc ccaaagtagc gatgggttgt acatcattga tcagcatgct
    15481 gcccaagagc gcattaagta tgaatatttc cgggaaaaaa ttggggaagt atctgatgat
    15541 ctgcaagaat tgcttgttcc atttgtgtta gactatccaa acagtgatgc tttgaaatta
    15601 aaagagcaaa aacacttgct agaagatgca gggatttatt tagaagaatt tggtcaaaac
    15661 agctttattg tacgggccca tcctacttgg tatcccaatg gagaagaaga atcgattatt
    15721 cgggagatga tcgatatgct gctgacaact ggaagtgtga gtgtaaaaaa attccgtgaa
    15781 gcaacagcaa tcatgatgag ttgcaaacga tcgattaaag ccaaccatta tttgaatgaa
    15841 gcacaagcac gtgtgctgct gaaggatctg gcacgatgcg aaaatccttt caattgtccc
    15901 catggccgtc cagtattgat tcactttacc aattcggata tggaaaggat gttcaaacga
    15961 atccaagacc cgcattaagt caaagagaag agggaaaaca tgaagattgt attagcatcc
    16021 caatcaccaa gaagaaaaga gttattggct catatcgttt cagaattcga gattgaacct
    16081 gctgatatcg atgaaacgcc atttccagac gaacagcccg tcgattatgt tcgtagaatg
    16141 gctgaagaaa aagcacgaac tgtctgggaa caagatgaaa aagaagacca tttagtgatt
    16201 gccagtgaca cgactgttgt tctcaatcaa gagatcatgg gtaaaccaga agatctggct
    16261 gaggctgaat tcatgctgaa aaaactaagc ggggaaacac atactgtata tacagctgtt
    16321 gttttaaaaa caaaggaacg agaagaacgg atactagcag aagcacatgt cactttttat
    16381 cctttgacag acgaagagat caaacgctac ttggagacgg gggattatgc ggataaggca
    16441 ggggcatacg gcatccaaaa tgctgcgagt gtattcgtca aagaaatttc tggagattat
    16501 tacagtatcg taggatttcc gattggtgct gtcaatcagg cactgaaaac attcatttaa
    16561 acaaaaaagc ggactatctg attttcgatt gaaaatccat gatagcccgt tttttttatt
    16621 gaaaagatta cttatctact ctgactaaga ttttacttca gctttaccga ctgcttcgcc
    16681 cgggcgaaca agtcctgatt ggtcaagaga aagtcctgca actttttcat tattggtcaa
    16741 agcaacaata atgtcagttt tcttgccagc ttgttctatt tctggcaaat ccatttcagc
    16801 aatcagggtc tctggtgtga caaggtatcc ttctttcacg aatacattga aaggaacacc
    16861 ctttagttca acagtatcta atcccatgtg aacaagtact tccagcccct cattagaaag
    16921 aataccaatg gcatgttttg tttcaaagac actcgtcact ttaccgttta ctggtgcata
    16981 gactttgccg tttgacggtt cgacagcata accgtcaccc atcatttttt gtgagaaaac
    17041 tgggtcattt acttcagtta tttccttgat ggtccctgca gcgactgcga ataatgtttc
    17101 ttttgttgca actgccgtac cagttgctga aacaggttcg aaagactgtg gcgttgctgt
    17161 tgcgccattt gctgtttgaa gttgtacatc agcagcattt tcaggaacag caggatcaat
    17221 cttattcaaa attccctgac gtctaaagat gatcgtcaag ccaaatggaa tgatgacagc
    17281 aatgatcatt gcgatgatga aaggtaccca tgtttctgct tggatagcta gtattcctgg
    17341 caaaccgcct actccgatcg cgttagctcg aacacccatc aagttagcaa acatgccagc
    17401 taatccagag ccgaccattg cagcgacgaa aggatagacg tatttcaaat tgattccgaa
    17461 catagcaggt tcagttacgc ctaagtaaca agaaatcatt gctggaatcg agatttgttc
    17521 ttctttttta ttcccacgat gtaagaagat gatggctaag actgcagagc cttgggcgat
    17581 atttgataaa gcaatcatcg gccataaatt cgttgatccg aaatctgcaa tcagctgcat
    17641 atcgatggca ttggtcatat ggtggagacc agtaatcact aaaggagcat acaggaatcc
    17701 gaatacggca ctaaacaacc agctgataga agacgtcaat ccagtattta cgatatttga
    17761 gatccagctt ccgactgtcc agccgatagg acctaaaata acgtgtgcag ctaaaacagt
    17821 tggtaacaat gaaaacaatg gaacaaaaat catcgagatc gactgaggga tatatttgcg
    17881 gaagaagatt tctagatacg ctaacataaa ccctgccagc atggctggaa taacttgcgc
    17941 ttgataacca atcatctgga cttgagcaaa accaaaatcc caaaatggaa tatctgctgc
    18001 ggctgtggaa gctacactat aagcatttaa taattgcgga gaaactaacg taattcctaa
    18061 aacgattcct aatatttgtg tagtacccat cttttttgca atactccaag tgatacctac
    18121 tggaagaaaa tggaaaattg cttcacccgg taaccacaaa aaggcattga caccattcca
    18181 aaacttcgag tgttcaacga ttgttccacc aagactttca aactggatac cttcaagtac
    18241 atttctgaat ccaaggatca atccaccgac aatgattgca ggaatcagtg gtgtaaagat
    18301 ttctgctaaa acggcaatag cacgttgaac gggatgaagg ttttgttttg cagctgcttt
    18361 tccttgttct ttggaaaccc cttcaactcc agatactgca acgaagtcgt tataaaaagt
    18421 agaaacatcg tttcctatga tgacttggaa ctgtcctgca ttcgtgaaca tcccttttac
    18481 gctaggtata tcttcgatcg ctttttcgtc cgcttttcct ggatcattca ggacaaaacg
    18541 catacgagtc gcacaatgac taactgcagc aatattttct tttccgccga tatcatgtaa
    18601 cagcttctcg gcatctgctt gatattttgc catatcaata aacccctttc tcttaacttg
    18661 tctatgcaag ttgtttcttc atttactata ctttttttcg gagagaattg caagcgtttt
    18721 attaaaaagt acgagagaaa atgatatcgt tttaaaaagc ttaaaataag cttttcttaa
    18781 aaataggaac attgaaatac aaaaagagct gtagtatagt gaagaaatga tggaagaacg
    18841 agtgagggaa aaaacatgaa taagttcaat gaaatttttt tagatttgga acagaaaatt
    18901 ttagcgaaag aatatcctcc gcattcgctt ttacccagtg agaaccaatt gatcaaaatt
    18961 tatggtgttt cacgagaaac aattagaaaa gcgctgaatc ttttgactac ggaaggttat
    19021 attcaaaaaa aacaaggaaa aggttcgatc gtactggatc ggaatcgctt cgactttcct
    19081 atttctggat tgactagcta taaagagcta caggagaccc aacgtattcc aagtgaaacg
    19141 atcatccata cgttagaaga aacagaagtg acaaaagcat tgaacgagat cactggctgg
    19201 gagatcggtg cgcctgtttg gcatttgata cgcgaaagaa aaatcaatgg cgaagtagtt
    19261 atattagaca ccgattatct attaaaggaa atcgttccta ttttaactcc agcacaagca
    19321 caaggatcga tctatgaata ttttgaaaat gagctttctt tgacgattgc ttacgcgcaa
    19381 aaggagatca cagtagaaga agtaacggaa atcatgaaaa cagcgatgga tcttcacgat
    19441 gacacttatg cagtagtagt cagaagcctc gttcatctgg aagatacccg ctgtttcgag
    19501 tattctgagt cggttcaccg attagataaa ttccgtttcg ttgagtttgc ccgacgccga
    19561 aaagtgtaaa tagttcaaaa gaaagcaaat tgttggcatc tgtccacttt ggcgctatga
    19621 taggatcaca aagggggcat ttttaatgga taaaccaata agaccagaaa aagaagaact
    19681 gaaagaaaag ttatcaccca tggcttatgc agtcacacaa gaaaatgcaa cagaacgacc
    19741 atttagcggg aaatatgatg atttttacga aaaggggatc tatgtagata tcgtcagcgg
    19801 tgaaccgtta ttcagctctg cagaaaaata tgatgcaggt tgtggctggc catcattcag
    19861 caaaccaata acgaaaagac aagtgcgcga aaaagccgat ttttctcatg gcatgcatcg
    19921 aatagaagtt cgaagcaaag aagcagattc tcatctcgga catgtgttta ccgatggacc
    19981 agtagatcaa ggtggtctac gttactgcat caattctgcc tcactgaaat tcattccata
    20041 tgaaaagatg gatgaattag gttatgggga attcaaatca cttgtagaat aatggaaata
    20101 cacaaagagc ggtacaatac ggggatttac tcgatcgtcc gctctttttt tattcaagcg
    20161 attgctattt gaaagaaacg ctccctagac tccttttttc acaaggtgaa atgtgctaca
    20221 ataaagggaa cgtatgtgtg caaaagaaag aggactagaa tatgtatgaa tatctgacag
    20281 gtgtggttac ctttatcaac ccctattaca tagtagtaga aaccaatggt atcggctacc
    20341 agatcgcact aggaaatcct taccgctaca gtagcaaact aaatcaaaaa ataaaaattt
    20401 atgtccatca ggtaatacgt gaagatgcgc atcttctgta tggatttgat tcgctagaag
    20461 aaaagcaact gtttttgcga ttagtaagtg tttcaggaat cggtccgaaa agtgcccttg
    20521 caatcatggc aagcgaagac cactccggtt tgattcaagc agtagaatcc agtgatgtca
    20581 cttatttgac gaaatttcca ggagtaggga aaaagacagc acaacaaatg atcttggatc
    20641 taaaaggaaa attcggtgag ctgagtatcg atacaccttt tagtctattt gatgaagcaa
    20701 acacaaaaga cgctacagct ctatctgaag caatggaagc tctctcggct cttggttaca
    20761 gtgatcgaga aatcaaacgt gtagaaaaac aattaaaaga agtagataat cagacaacgg
    20821 atgagtatct acgccaagca ctcaagctaa tgatgaaaaa ataaggagga gaccaaatga
    20881 cagatgaata cttgttatca ccagaatctg gcgaaaatga actgagtttg gaaaaatctc
    20941 ttcgaccaca gctgctttct caatatatcg gacagagaaa agtcaaacaa gaacttcaga
    21001 tttacatcga agctgccaga aatcgggaag aacctttaga tcatgttctg ttgtacgggc
    21061 ctcctggatt aggaaaaacg acgatggcca tggtcattgc taatgagatg accgtaaata
    21121 ttcgtacgac gagtggccct gctatcgaac gtccgggtga cttagtagca atcttgaatg
    21181 aactggaagc aggggatgtc ctgtttatcg atgagatcca tcgattacct agagtggtag
    21241 aagagatgct ttattcagct atggaagatt tctatgtaga tatcatggta ggacaagggc
    21301 caaccgcaca tccggttcat ttccctcttc ctccctttac tttgattggc gcgacgacac
    21361 gggcaggtat gctttctgca cctttacgag atcgatttgg catcatttct catatggaat
    21421 attatgacga acaggatctg caggagatcg ttttacgttc ttcggatatt tttcaaacag
    21481 agatcattga agaaggggca ttggaaattg ctcgccgatc acgaggaacg cctagaatcg
    21541 ctaatcgctt gctcaaacgg gttcgtgatt ttgcgcaagt ccaaggagac gggaaaatcg
    21601 atcgtcctat agcggatcag gcacttactt tgctacaggt cgatcaggct ggattggatt
    21661 atgttgacca gaaattgttg cgaacaatga tcgagttata tggcggcgga ccagtagggt
    21721 taagtacgct ttcagtaaac ataggagaag agcgtgagac ggtagaagat atgtatgaac
    21781 cgtatctgat ccaaaaagga tttttaaagc gtacacctag agggcgaatt gctactgctt
    21841 atgcctatga acattttggt tacgactatc atatatgatt tttgctttta gattggagga
    21901 aaatgaatga gtgatacaac acgtacgaaa caattgatca aaaacgtatt gattgatttg
    21961 tgccaaacgc aatcttttcg aaaaatcagc gtccaaaaaa tcgcaaacga agcaaaaatc
    22021 aatcgacaaa cattttatta tcattttaca gataaatacg atttgcttcg ttgggtctat
    22081 tgtgaggatg cattgcatta tttagatcca caatgtcttt cacttgataa ttgggaagag
    22141 caagcattga aaatgctgaa agcaattgct gagaagaaag aattttatgc aaatactgtg
    22201 ctttctgacc cagaaatttt acaaaaagag ttttctcaac tgatccaaaa atcatttatc
    22261 aagatttttg aacaaatgga tgaagaaaga caactttctg caagagacaa actattttat
    22321 gctcgttttt tttcttacgg ttgcagtggt gtattagtca attggatcac gaatgaatat
    22381 gaagaaacac cgatggaaat cgctatgcag cttttccgtt tagccaagga tacggaatta
    22441 tattcttatc gtctttatgc aaaagaagag ttggaagaac agtaatagaa aaattttttg
    22501 ttggaaaagc aataatcgct aaaaggagat ggggaaatga caaaaatttt atttgtttgt
    22561 ttgggaaata tttgccgttc accgatggca gaaggcttgc tgagaaaacg aatagcatta
    22621 gaaggaaggg aagcagaatt ttttgtggat tctgctgcta caagcacgta tgaagttgga
    22681 aagacaccgc accctggaac gaaaaaaata ttaaaccaag aaaaagtaga tatgacgaat
    22741 atggttgctc ggcaaatcac accccacgat tttgaaactt ttgattggat cattggcatg
    22801 gatcaagaaa atgtagaaga actgaaacga agagcaccac gctcagcgca ggggaaaatc
    22861 catttgtttt taagtagcat tcctggaaaa gaaaaagaaa atgttcccga cccatactat
    22921 accaataact ttgatgagac atatcacttg atcacagaag gcctgaatca ttggtggaat
    22981 atttggattg atgaaaataa aataacaaat aatttgtaaa gttaacgctt tctttttaag
    23041 gcgatgttag agcatttcct tgtttttttg taaaatgtta ggtaaaataa aattaattaa
    23101 gtaacacttt cttagctaaa ggaggagtgc attcgatgaa cgaagagaca gtatcgccaa
    23161 tgaagaagct tacgaagtta gttactcata cttcgtatca actttttgat tcttttgtaa
    23221 atgacactga agaacatgct aagaatgtac gattgcaagg aaagtttatt cttgagctgc
    23281 aaaaagctgc tactgaacat agtctagtta tcttacaagt aagagcaaat cgtttgagta
    23341 gcaagtatga aacgatctca ggctgggtgg cgacaaaaac ggtcgaaaaa gaccgagtga
    23401 tgatccgcct acaaaacgaa gagcagcaga tccggatggt tcctgtagaa caaattgaaa
    23461 aaataacaat cctttcacca gcaggggaac aggaacggtt atcaaaataa tttataccag
    23521 atagaaaagc acgtatgagc ttgtaccatc aatcattact aatcaaaaat aaccgaatgc
    23581 tttaagctga tatcagtaaa acggaacgtt ttaggatgag tatcatagca tgacagcatt
    23641 cggttgatta gttgaatcga ttggatggta caagtttttt tgataaaaaa aggtcctgct
    23701 agccggggag ctagcaggat aaggagttaa aaatgaaaaa gtgttgttag ggttgtttgt
    23761 tggtatgctt atataatagt cattagttgt gaatattttg tgacgaaagt tttcgaaagt
    23821 tgttaag
//
LOCUS       DAKCAA010000040        23462 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000040 DAKCAA010000000
VERSION     DAKCAA010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.040"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(30..254)
                     /locus_tag="OUE31_001746"
     CDS             complement(30..254)
                     /locus_tag="OUE31_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222754.1"
                     /translation="MEQTNHITEETRKFICLESFYSEGRYCNKGETYTAYPIEGGFKL
                     VFENGDMNFTTELFECVVETWSDVLLEVTK"
     gene            complement(284..673)
                     /locus_tag="OUE31_001747"
     CDS             complement(284..673)
                     /locus_tag="OUE31_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222755.1"
                     /translation="MNEETELFIKKVNFLVEKYFFTKHKIMYLIKGLIGGIILWILTF
                     FSLFGGFTNYKKLVDENVKQISASESLRHQAEDLVSNPLFIGGMVEVIIISFVIGYLG
                     MCIFQIIFDLIRGKVFQGFKSEKINLR"
     gene            complement(666..1055)
                     /locus_tag="OUE31_001748"
     CDS             complement(666..1055)
                     /locus_tag="OUE31_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222756.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIEKCY
                     YGQHYWSEEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     SKLAQSYLEEKAGAIKDKEEMEKFAIE"
     gene            complement(1217..1747)
                     /locus_tag="OUE31_001749"
     CDS             complement(1217..1747)
                     /locus_tag="OUE31_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222757.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            complement(1763..2128)
                     /locus_tag="OUE31_001750"
     CDS             complement(1763..2128)
                     /locus_tag="OUE31_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222758.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDQQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            complement(2134..2877)
                     /locus_tag="OUE31_001751"
     CDS             complement(2134..2877)
                     /locus_tag="OUE31_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222759.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            complement(3008..3730)
                     /locus_tag="OUE31_001752"
     CDS             complement(3008..3730)
                     /locus_tag="OUE31_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222760.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            complement(3992..4576)
                     /locus_tag="OUE31_001753"
     CDS             complement(3992..4576)
                     /locus_tag="OUE31_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222761.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTIISNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            4698..6281
                     /locus_tag="OUE31_001754"
     CDS             4698..6281
                     /locus_tag="OUE31_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222762.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALV
                     LDLIDKLSDLANIYEDITSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLPYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLKILKEEISKYRFTAESREEINKSLGENQQITYTK
                     GVFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGSN
                     NEELQNHLNSLLDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNTVTMDQGFQLKDKELKNLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            complement(6538..6873)
                     /locus_tag="OUE31_001755"
     CDS             complement(6538..6873)
                     /locus_tag="OUE31_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222763.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(7048..7542)
                     /locus_tag="OUE31_001756"
     CDS             complement(7048..7542)
                     /locus_tag="OUE31_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222764.1"
                     /translation="MNKLPEKNRVFRLKGDLSQFKIDENGQFFVWMRHEHCWCNPFEL
                     KKENEIRTKIANGEWDYLFRWEDESFIANDMDHAFVSFLDNTWGTWYDCYLEKLGFQN
                     IDIDAIECLKEVDQKYEEEPYYLLQQKLANNSVFQVEIWENEDGTYEGLAQEIPFSDR
                     KSSI"
     gene            complement(7539..7766)
                     /locus_tag="OUE31_001757"
     CDS             complement(7539..7766)
                     /locus_tag="OUE31_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222765.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARVFFNEVKGMREQYEVVEA"
     gene            complement(7933..9903)
                     /locus_tag="OUE31_001758"
     CDS             complement(7933..9903)
                     /locus_tag="OUE31_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222766.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            complement(9918..10784)
                     /locus_tag="OUE31_001759"
     CDS             complement(9918..10784)
                     /locus_tag="OUE31_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222767.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            complement(10774..11007)
                     /locus_tag="OUE31_001760"
     CDS             complement(10774..11007)
                     /locus_tag="OUE31_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCU0222768.1"
                     /translation="MREEKIVYPVIQNNQENITSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            complement(11019..13175)
                     /locus_tag="OUE31_001761"
     CDS             complement(11019..13175)
                     /locus_tag="OUE31_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222769.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEAYQKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEGDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNMFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAEDVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSASDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSSIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIIAVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            complement(13175..13417)
                     /locus_tag="OUE31_001762"
     CDS             complement(13175..13417)
                     /locus_tag="OUE31_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222770.1"
                     /translation="MVFDREKMLTHANEVLMSGLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTIDRKKGVLQ"
     gene            complement(13527..13865)
                     /locus_tag="OUE31_001763"
     CDS             complement(13527..13865)
                     /locus_tag="OUE31_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222771.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNEQLG"
     gene            complement(14265..17906)
                     /locus_tag="OUE31_001764"
     CDS             complement(14265..17906)
                     /locus_tag="OUE31_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222772.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFMRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGQDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQWHTPIA
                     VAIPENEDDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTALKDRESLTKETEKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNENNRTNNSKSTSDNSGKSNQSTKKPSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKIAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            complement(17909..19854)
                     /locus_tag="OUE31_001765"
                     /pseudo
     CDS             complement(17909..19854)
                     /locus_tag="OUE31_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
     gene            complement(19896..20954)
                     /locus_tag="OUE31_001766"
     CDS             complement(19896..20954)
                     /locus_tag="OUE31_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HCU0222773.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFT
                     KDSFGDMKTTFKYLTLTD"
     gene            complement(21073..21528)
                     /locus_tag="OUE31_001767"
     CDS             complement(21073..21528)
                     /locus_tag="OUE31_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222774.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            complement(22113..22916)
                     /locus_tag="OUE31_001768"
     CDS             complement(22113..22916)
                     /locus_tag="OUE31_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCU0222775.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
BASE COUNT         7030 a         4547 c         3192 g         8693 t
ORIGIN      
        1 agttgcttaa ttctactaga taacattgat tatttagtga cttcaagcaa cacatctgac
       61 cacgtttcaa caacacactc aaacaactca gtggtaaaat tcatgtctcc gttttcaaaa
      121 actaatttaa atcccccttc aataggatat gccgtataag tttcaccttt gttacaatac
      181 ctaccttccg aataaaacga ttctaaacaa atgaatttcc tagtttcttc agtaatatga
      241 ttagtttgtt ccactattct tctcctctca tagcctatta tctctaacgt aaatttattt
      301 tttcagattt aaatccttga aagacttttc ctcttattag atcaaagatt atctggaaga
      361 tacacatacc taaataacca ataacgaagc taattattat cacttctacc atacctccta
      421 taaataatgg attacttact aaatcttcag cttgatgtct taatgattca gatgcactaa
      481 tttgcttcac attttcgtct actaactttt tataattagt aaatccacca aataaagaaa
      541 agaaagtaag tatccataaa ataattccac cgatcaatcc ttttattaga tacataattt
      601 tgtgctttgt gaaaaaatat ttttctacaa gaaagttcac tttttttata aataattccg
      661 tttcttcatt caatagcaaa tttctccatt tcttccttat cttttattgc tcctgctttt
      721 tcttccaaat agctttgtgc aagtttactt acttttttca tcatcaaatc tgagagtttt
      781 tgattatctt tttcgctgta aaataatcta ctcgttaaac ttttaggata atctttgata
      841 gaatatgcat cccaaacaat tctttgaaca tattcacgat ctatattttc tctgacttcc
      901 tcactccaat aatgttgacc ataatagcat ttttctatta cgttgttagc agaaacttca
      961 aaataggatt gttccctttg tatcctcata ccaatcatca tagcgcagga aataactatt
     1021 aataacaatc ctgtttttaa tctattattc cacatgcagt ttccacatcc ttatcttgat
     1081 aaaaatcctc ttgcccctct ccaattactg ttttaaatat aaccaccaaa acaagatcat
     1141 gctgagaaat ccaagagtat ataagatgat acattctttg ttaattatcc aaaaaactct
     1201 gatttctttg agcttttcac gcattaggaa acaccttgtt atatcttttt tgtatttctt
     1261 tcaattgttt tttaaaactc ataaacaact gttcatgatc tggtctaagc gttagaatat
     1321 ctaaattatt tatctttttt aattgagtaa taaaatctat tttggatttt ctttcaatat
     1381 caaaaccgac aataatcttt cctgttggat caacgcattt cacttgaata actttgtcat
     1441 tttgcgatag ctctaatatt gatgattttt cttttgcctc ttccaaaaga tgttctaaca
     1501 cttcgttagg tgttccatga tagtaataaa tcatggtctt ctcgaaaatt tttatcggat
     1561 caacaccata ttcttttccg attcgataaa aaaatttcat tggaatttct tccggatttc
     1621 tgttcctgct tgaccagtta gagatggttt gataatttgc aaaatgaatt cgttccgcta
     1681 atctctgaac tgtggtctct aaatcttctt ctattaattg ttttacagca ctaatgtttt
     1741 gtgacatttg ctttctaccc cttcaaattc gttgcattat caattctaag atttcatgtt
     1801 ttagtgcatt tctatctaca ttttgctttt ttaactctgc accataatat cttcgcaatc
     1861 ccttatccaa gcatacaatt ccttgatcta atagatcata ttccgctttt tcaaaccttc
     1921 gctttgcctg ctcaacaagc aaaatgatat tgtgatgtat ctgattaaac tgctgatcat
     1981 attcctctaa agttttagca tctaagttag caatatgatc ctctgctaat ttttgtgtta
     2041 aaaataattc gactttctca gatttcaaca tctgtatttt ttcatactct tgttttgctt
     2101 ggatatagtc atctttcaag ctagacatct aactcatctc cttgcctgta taaactgata
     2161 cggactgtcc aaaattgaat aggttggtga tgacttcaag aagacttcac ctttttcaca
     2221 tgaaaataaa ccaattaatt cttcaatttc atttacgatc agatatttat tagttaaaat
     2281 tttcccattt tctttttcta gctcgacaat cgcttgattc catgtatttt gcactaaatc
     2341 ttgaatcaat ttcaatctat ccactttttt catctcatac agggcaattt cagcttgttt
     2401 aatgcctttt aatttgcgaa aggcatattt gtattgtgtg taggttaaaa agcctgtgta
     2461 gttatacatg ggctttcctg atgtcttgta gtcatttaag cttggatata tttcagtttt
     2521 ccatttttct tctgaacgtt gatcaataat tcttaatttt tcaggtaaat caatttcata
     2581 gtattcttca attttcagct cacgataaag tagatgtttt tccttttctt tttcaattac
     2641 aaaagaatta tttcccttca gtttagctat ttcttcactt gtgagaccaa gcctaatttt
     2701 ttctacttca cttctaagtt cacgaatact tgttgccttt aaccacttcc catttgcacc
     2761 gttattgtaa ccggtaagta actgtatttt ataaattcct tcaccatgaa gcaccttata
     2821 tataccaacc tgattctttt gcggaatatg agcttcattt gcactgattt ctttcattac
     2881 gcattctcct ttataatcta gttaattagc ttgtgtgttt cgagtagttg agtaagaacg
     2941 tttgtttcag aaatcattta tttgttatca cttaatttta aaaaaatagg gcttacgccc
     3001 taaagaacta tttaactttg gattgatcgt ccataacagg ttctgattgt tgatataatt
     3061 tatatgctcc caaatccata taatatttag ttgtactttc aatcatttca tcagttgtat
     3121 ttgttgtcat tcccattaca tcccagtata gtgtgccgtt aactttcttt ggtgttacta
     3181 ctgcaactgt tggcgtatga tattgattgt tctcatcagc cagaccagga atgttttgta
     3241 cccactcagg tacaccatca gtaatatcta cagcaactgc gtaatactcg taagctggtt
     3301 tatttatggt aatatcatgc attaatgttg gagcataact aaatccttct tttatttctt
     3361 gcatgatttt tgattctgct ttttgacaat ctggacaatc aggtttgtaa agaacgatag
     3421 tcagattttt attttgcaat ggatcattcc cataattttc atcatttttt actgtattaa
     3481 taaagttgtt ataaacttca tccggctttt gacctttatt aatgtcttcg tatttttgat
     3541 acttttcagc attattttca gtcattgaag acattgttgt tgatgccgat gtagtgctgt
     3601 ttttagtaac catcgtacta ctagactttg tgtctttgtt attattagca ctattagttg
     3661 taccacatgc tgtaagggtt attaatgctg ctgtcgataa caatacaacc ttcaatttag
     3721 ttgatttcat tttattcacc tatcctttat tcttttgttt aacaataaaa gaataacccg
     3781 tactatccaa taaaacaaca gcatcaatat ggaaacccaa accatttgta caatccaagc
     3841 ataaagacta aataataggt attgtggatt tttttgaatg attgtatttg agatgccatt
     3901 tcctacagta aaatacattg ttacgaaaat aacaccttca attatcaagt gatttgttgg
     3961 ttgatttata atttttttca tatttttact cctaaactaa atttattctt cctgctaaat
     4021 attgaaaatt atatgggttc tgcacatatt ccctaagttc cttaatactt gtttcaatat
     4081 caccaaaggc tgttttaatg tttgctgacc catctttata tacaatcatt tccccttcac
     4141 ccatacagaa agaaatttca gtattagaaa tgattgtttt ttcagcacga ccattgataa
     4201 tttcttgacc atcacgccat ataaaataca taagataaaa tacctcataa gcgttgtatc
     4261 cagtatccgt tgtcattgat accaaaacat cagcatcttg tattcctgat aaagctaatc
     4321 caatttcatg gatcacatca acttcatttt cttcccaatc tccactttcg aagacggtat
     4381 aggtttgatt gttagcaaat ggttttctct ctatatcgaa cattcctttc caatcaagaa
     4441 tcatgtaccc gattaaattg tgaaagaaaa ttaaataaaa taaatacaat aagatgctaa
     4501 ctacaaaaat atcagccatt attgacatag gattatcagg atataaccag atgtaaaacg
     4561 attgtttcaa atccattttt ccatcatctc gctctatata tttatgctat catgataaca
     4621 taataacata aatttgtctc gctttttaat atttttttat ggtaaacttg tcatacaaac
     4681 aaaaaaagga gatttatatg tttatattag atgatgaaat aaaaaaagtt aaaaatccta
     4741 gaattattcc attattagaa gaagttcgaa gtagttttta tcagggaaat tatcgttctg
     4801 caatagctgt caattacagt gcgcttgttt tagatttaat tgataaatta tctgatttag
     4861 caaatattta cgaggatatt acttctaaga aaattttaga agatatagct agattaagaa
     4921 aaagtgatcc aaattctcca aaatgggaaa tggaactact agaaaaagct tatagttcaa
     4981 ctgagctaat tgatagctat gaatatgagg atttaaaata tattaaggat caaagaaatt
     5041 attcagctca tcctgtagtc acttacaacg gtaatacttg ggaattaaga gatataacaa
     5101 aagaaacttg tcaggatgtt atacggaagt cctatgaaat tatattccta aaaaatccaa
     5161 tattaggaaa aaaagtaacg atcgaaatta tacaatatgc aagtcgcata catgctatgt
     5221 ctgttacccc tgaagaattt cactctgcac taaaaaatag ctatctaaat aaactaagcg
     5281 aaaaagcaaa agaaaaccta tgtaagacag cctttaagtt tgtttttcaa ttaccttatg
     5341 gaaatgagga agcagataga gatagggaaa gtactttcag actacttaat gccctaattt
     5401 ttgataataa agaattctat ttaaaaattc taaaagaaga aatttcaaag tataggttca
     5461 cagctgaatc aagagaggaa attaataaat cacttggtga aaatcaacag atcacatata
     5521 caaaaggggt ctttttactt acttttatag ctacccatcc agaattacaa catgattttt
     5581 cagacgagac aattcaaaat ttacaaatat caataaatga ttttaaaccg aaacaacaag
     5641 tactaacaga aatagaatat tactaccgtt tacgttcact tgcagttcta ggaagcaaca
     5701 atgaagaatt acaaaatcac ttaaatagtc tacttgatcc tatacttcag caaaaaatga
     5761 gagtttcttc gctaccatct tcaacattag aaacaatata taatcaatat ttatattttg
     5821 gtgaaaaaga gatgttcata gattttatga tcgaacatct taccgatgct agttcattca
     5881 ggttagcaga taaggatatg gaagtattac catggattta caataaatta aatcaggagc
     5941 aatttaacaa attactatac aacctaaatg gaaataatca attttacaaa aacagtaatt
     6001 ttccgccttt tatttctaat ctgttagact tttataatca gaaattccaa gtgaatttac
     6061 gtaaacatta tagtgggctt ctatatccaa atacagtgac tatggatcag ggttttcaat
     6121 taaaggataa agaattaaaa aacctgtatg aattagctga atcgaaaagt gatatgtatc
     6181 tagacataat agataatatt attaataagt ctgaagacta tttaagaaaa gaaatcaatt
     6241 ccgagaaaga attgttaaat tatgttcaca aaataaaata atttcttata acacaagatg
     6301 cacttttata gcgtatattt actttcaaat taaactaatt agttatattc tcacaatagc
     6361 atttaataat aaatatactg tcgcttgatt tatatatttc cctcttcttt ctttaaaatc
     6421 tctctttatt ttgatataat aaaatagaaa tcgcaccaaa caatgaaatg gcggaaaaca
     6481 tttcattgaa aaaaggattg aacataatgt tcaatccttt tttatagtta taatcaatta
     6541 acattcggtg tgtgaaattg aatcttcgat gctttcacat ggaaaattat tgattccttc
     6601 ttcactcatt tcccatgtag tatagaaagg agttaactgt cctccatact cctgaataat
     6661 aaaatatttt ccatcattga tatggttaca acagtacact ccaatagttg gatactcgac
     6721 tactaaaaat tggtctggat caaactgttc ttttttcaac atttctcgta tttgaaacaa
     6781 atgatccttc tctaagcaat caggtaattc ctttattctt tgcgttacta atgacccctc
     6841 tatcgctttc cattcattta aatattgttt cataacaatt cattcctttt atgttaacta
     6901 tttttcctag gaaattgttt taaaacgcca ctctcccaga aaacgtaaga tttggttagc
     6961 tagaatatac cttccagcta accacaattt tccattacta tattgtaagc ttgctttcac
     7021 ttcataaaaa ttgctgatat actcttttca aatcgaactc ttcctatctg agaagggtat
     7081 ttcttgcgct agcccctcat aagttccatc ttcattttcc caaatttcta cctgaaacac
     7141 tgaattattg gctaattttt gttgcaagag ataatagggt tcttcttcat acttttgatc
     7201 gacttcttta agacattcaa tagcatcaat atcaatattt tgaaagccca atttttctag
     7261 gtaacaatcg taccaagtac cccatgtatt atccagaaat gagacaaatg catgatccat
     7321 atcatttgct ataaaagatt catcttccca tctgaagagg taatcccact caccgtttgc
     7381 aattttagtt ctgatttcat tttctttttt taactcaaag ggattacacc aacaatgctc
     7441 atgtcgcatc caaacaaaaa attgtccatt ctcatctatt ttaaattggc ttagatcacc
     7501 tttcaatcta aatacacggt tcttttccgg taacttattc atgcttcaac cacctcatac
     7561 tgttccctca tacctttgac ttcattaaaa aaaactctcg ctttttcttc atcagtaaag
     7621 tttttataca actgattaca ataatgaggt ttttgaagtt tctgaatacc tatactaact
     7681 tcaaatcctt cttcatgttg aattaggatt acttctgtgt ctctacctag aaatattcga
     7741 tctaaaattt ttatgtttgg tttcattatt taacctccgc tataattatt tcactcagta
     7801 aggtttcgct ttatgaaatt tctatagttc tcttttcaca aaacgtacca tgttctctaa
     7861 gactgttttt agtctcaaat atacatgttt tttcttatcc tttccttata cactcaaaat
     7921 caaagataaa acttaaagaa taaactctcc aataacaaaa ttattagtca gatccactgg
     7981 tctcctgatc tgaaatttat tacttcttcc tgttgtcaaa tactgtctca aatcaacaga
     8041 aagtttttga tcatcttctc cttttctagc aggagcaact tttttttcat acttcattaa
     8101 ctctccactg gtcatctttc caatgatagt gtaattaaaa tcactttcaa aactttggta
     8161 aatttttcca tctgtattga atatatcagc tgtttcaata tcttctttgt attcattgtc
     8221 ttctcctgaa ccgattgtat caaatagaaa ggcaagacga attccatctt cttcaagcat
     8281 tgttaatctt tttttaatta gaccaacggt ttcaatagat aacttatcga agccgtgaat
     8341 cataacaata tcatcttttt ttgcttgtga tgtgatgaaa tcaaaggtat ttaaaaattg
     8401 agcttccata acattggttt ctgctcttag atcacctaag ttatagtaaa actgtaattt
     8461 gtcactttta ccgatttctt tcagtgtcgt tctttgatta aacattctag agaagctgtc
     8521 taatgctgtt ctcaatgtgt cttttaatac aataatacga tcgacttctt tttcagtacc
     8581 agattttttg gcttttgttt cagcattagt caaatagcta ataaaatccc caagaactgg
     8641 cattgtatca ctactgttca ccaaaagttt cgaacgttct tcataattaa tatcccaaag
     8701 tttctgactt atataaaagt tacctaattc ttttttcaat aaaactctag ttgcagaatc
     8761 taatgttctg cctgctaaca aataaaaaat ctgagttagt ttatcgagat tccgtctata
     8821 taaatcacca atgtcctttt gattaccaaa aagctccaaa gagttaagac cttcttcagc
     8881 caaattaacc ttttctatta cactgtttaa cgaaggtttg gcaacaaatg ttctaccagt
     8941 tggatcacca aagtaatcaa atttatttaa gacaatatga aaagttcgtt tatgatttgc
     9001 cattgcatta ttagcaatca attgccccca aagtgatgat gctgagattt tttcatcata
     9061 gcctttaatt gtagcgtttt tgtgtgatgc cactaaaact ttacttgtaa aagaatcatc
     9121 cagtgccata aaagctacac cacttgcgta gctagtagac atagtaccga tagcccatcc
     9181 attcgcatca tctaaacctt tacgaattgc atgatcattt cctgcaaaat ccgaactcat
     9241 agacgtatac tcatagacat tcccgattgg ttcacttaaa agtctatcaa acagatcacg
     9301 ttgatctcct ccatatgaca taagctttaa tccatacatt ttttcatcat acaaccgttg
     9361 gagtttaatt agctgttcgc tgattttatt aggagaatcg gatactaata ggatttctag
     9421 cttccaatca ataattttat ttgccatgct gtctagtaaa gatgctgtat tcaaatccat
     9481 aatccgcata acagttttgc taatttcagc atctgaattt tttccttcta aattattttc
     9541 ataactattc gttgatcccc caacattctc gtgcattatt tcttgttgat ctttttgtga
     9601 cactggctta tctgcttcaa ttagataggc ttttacccct tctactctca cttcaggaat
     9661 agctttaacc atccaaccaa atccataatt tctattcatt ccataagtat tcactaattt
     9721 cacaattgtt ccccaccgct tacctgtcct aatgtaagat ggtgtaaatt gataaccaac
     9781 taaagatgtt aaatcactaa caaaggtatt attcactacc tttgaatttc tagttttttg
     9841 ttctttttta gtttttctct tttttttgaa atttaatagt tgtgatctac ccataatttc
     9901 catttaatct ctcacctcta tttcagtgca taaatatcag ataatatttc ttttgtttgt
     9961 ttagctgaca actgagtgac actataataa agtcctctac tcgtatagtt ttctaaacgt
    10021 tccacacctt catccaatac catcttagat tgagatttca agataagata ttggattact
    10081 gttgttttca caccatcaat atattctgat acaaatcgtt cttgctgatc tattatgtca
    10141 aagactgctt tgttactcct tgcatttcgt ttttgtattt tcatatttcg agtttgtctt
    10201 tccgtattct gaggttgaga tgaagtgatt ttgatttcag ctaaggaacg atctctggta
    10261 ttttgatatt gtattgattt cgattcctga gccataactt cttctggaaa agcggttagt
    10321 gatgtagccc catctagatt gaacattaat gctacactcc catctcgata tacgattgtt
    10381 ccatcttgtt tcacttttaa aatctctgtg cctcgaaatg gtttcttttt ccccatagat
    10441 actcttgctg aattaactac tgatttgaac agtctaatag aaccagaaat caatgaacca
    10501 ctagatggat caataaacat atactggcta attagaataa gaaatccaat tatcattaat
    10561 aacgttggaa caaaaataaa tttcagttta atcgtatcag aaactaagta aacaattgat
    10621 ccaagaacaa cgactgcaac aactatagct gatacaatta atctttttgc tgtaacagaa
    10681 taggtgctat tgacatgctt ttcaagccat tcaactctga caattgtttc agaaggtttt
    10741 tgatgtaagt tatgtttaaa tccatagttt gagttatctg ccatcagaaa tacttccttt
    10801 cacgttcaac ttacggtaaa cacctacagt tatcactatt gcaacaataa gcaagccaat
    10861 taaagatatt gacttgctca ttgtctcgtt cgtttgtggt agttcattta cctgatacac
    10921 gagctgtgct tcctgtaagt gctgagaaga ggttatgttt tcttgattgt tttgaattac
    10981 tggataaact attttttctt ctcgcataat agccctcctt agttattatc agataagtga
    11041 gcttgaattt tgtactgatt tccgtctgga gttttcacaa ctgctttttc tccatcaata
    11101 gaaatcactt cagccttagt tgttttccca tcaatactga tgacaacatc tttcccaact
    11161 ttgaactctg tagttggtgt tgcttcatag ctactatttg ttgaagcaga gttcgtattt
    11221 gtcccaatcg aattttccac tctcgaaata gatgtttgag tttgagcctg tgcttgttga
    11281 ttattatgac taataaagta ggatgatccc aagatcgttc cgcaagccat tgcagcgaca
    11341 gcaatgatag tagccatctt tttacttgta aaatcacgtt ttgaacttga ttgattttct
    11401 gtagcaactg ctaatgattt cgttttttct gccatttgag ctagatcact tcgggaacga
    11461 gataagtctt ctcttaaagc ttcactttgt tctgccaact tttcgctatt taatttataa
    11521 ccctctgcta aatctttgac ctctttcatt cgatctttat attcttcgat agttttttgt
    11581 tgctctacaa gttttgtttc taattctttc gtgttgttag ctacctgctt ttcaacttct
    11641 tctttgttcg caaaatattt gacaaccaca tctgttgttt tctcttttgt atcatggaac
    11701 tcagcttcat tttctgactt tgttttttcg acaatctcta aagttttttc ttgcacgtct
    11761 gttaatgatt tttcaatttc tggtttcaat gaattgataa ttcgttccac cacaacttct
    11821 tttgcttctt ggctttgttt caatgcatcg tttttaatag attcaattgc ttcttggtac
    11881 tgttgatcaa gactttcttc agttgctttt ctatattcat cttcttgttg tttaacttct
    11941 ggtaaatgtt cagcatcata ccgttgctct agtttcttta gttcagcatc caaataagcc
    12001 tgtttcgcca tatcataatc tttacgaatg atactggatt tttccatcac taaatcatca
    12061 attttagatg cttctgcttc gtagctctct ttagcaaccg atagtgtatt tgtaaactga
    12121 ttttgaccat ttaatgaggt tgcttcctct atccgcaaaa gctcatcagc taacatttgc
    12181 tttcctttga ggatcaattg ctccttcgtc ttatttaatt cactgttgat tttattatta
    12241 gcaatagaga tgcgagcgtt catactctct ttagctaaaa acagcaatgg tttcaactca
    12301 ggtatggata gcatctcctc gtttaaatcg acagggtcat taatctcatc taaaactaca
    12361 ggttgaaatt tgtcagcaat gatctgttca aaattttttt ctaaaaaatc agcatctaag
    12421 tttttcggta catcacttgc agatgtgatt ttttcagctt cataaacata attttctttg
    12481 tcactttggg attcgggttt ttcatcaatt tttggttgtt ggtaggtttc tgtttgtatt
    12541 tgtgtttctt ctatgcttac ttcttggttt tctgcttcgg ttggtttgtt atcatccaca
    12601 aaaagagctt ctttttcatc tggtacatct tctgctacag cttcaaattc aacttcttca
    12661 gaagagttga aggtctcagc gattcgttct aatccattag tagctacttc taattgctct
    12721 actgcgctat agaagtctgt agcttcttca acttctgatt caaacatatt aggatcatcc
    12781 ggaataacta ataattgacc actactatcc ataaaacgga cacctgctaa tagcttctct
    12841 ttaaattttt ctggtagatc agctacataa ttcaaacttg acttcaatag aacgacatac
    12901 ttttcagaat cgagaatagc atcaccctca tctataactc cctcactgtt gagcttttgt
    12961 acatcttcaa ttaccatata atttttcttt ggtaaatctt tggtcagcaa cgcatcgaat
    13021 tctttccata cctttgcttt agcttttttt gccttcgctt ctttttcttc tttttggtac
    13081 gcttcgagta attgtggctt caaagagagt gcaactacag gaactgtttc tgccacataa
    13141 ttaatagatt cggtaatatc tttgaatttt gccattattg taaaactcct ttttttcggt
    13201 caatagttct tttctgtttg tctagcatat atacatatgc tttttcgaat ttaataagcg
    13261 tttcaagtct ggctttttca atctttttac tcccatttcg ataatcatag aactggttaa
    13321 cattcatatt cattattttt gccagttcgg tacctttcag accgctcatt aatacttcgt
    13381 tggcgtgagt taacattttt tctctatcaa aaaccatctt acatttactt tcttccctca
    13441 cttctaaact acgcttggag cgtagttttt tggtaaaaag taaattgaac aaatcggcat
    13501 attatccaaa tttgttcaat tcacttttaa cctaactgtt cattttttgg aaattttgaa
    13561 actagataga taccaacaac tggaataagt gctgatatga tattagcttt ttggttcaaa
    13621 tcattacctg ttttagtacc cattgtgtaa agcataacag ttgtaattac aggtataata
    13681 aagattgcga taatcgcccc aacatatttt aatccatctc cccattttgc atcaccaaaa
    13741 aatttcattg cagtgaatcc tggtttcaac gaaaaaacga atgccaagaa atacaaaaca
    13801 acttgtacta aagttttcat atcaggcgtc attccgctaa ccaaattttt aatagaatcg
    13861 aacatataaa aacctccttt ttaatatttt taataagtta attatatcat cgacaaattt
    13921 tatttgttca cttgtcaatg atctaactaa gaaaaagacg tctcgatatt tacatcttta
    13981 tgttatcata ataacataaa ttttagatga ttaaaagaga ttttccatta aattatttca
    14041 ctttttttat tggctaaaaa tgctggttta tcaagttttt gtttagataa taattctgtt
    14101 ctttaccagc ataagccctt tttaattata caattttgaa cagtaaatat ttaattcatt
    14161 tatagacaat ttaaaataat ttttttgcat aaatagaaat tttccttgac atcttcagtt
    14221 agaaatcaaa gtaaaaagaa ggagcaaatc aatgctcctt ctttttactc gtcttcagac
    14281 ttattttcag ttgatttttg attaccgtat tttacaatat agtccttgac tgacatggta
    14341 gatttcttca ctactttacc agttttggat gctcctgtag cagtagcctt ggcaatctta
    14401 gccgttcctt tacctatttt aatagcttcg tttttagctt cataggttat ccctgctaga
    14461 ctaccttttg gagcttttgc taaagcttta tctgctgagg tgtaaacatt tttaccagtt
    14521 tttgatagat attcaacggc tgatttagct gttgatggtt tcttggttga ttgattagat
    14581 ttccctgaat tatctgaagt agatttagaa ttatttgttc tattattttc atttgtcagt
    14641 tcaggttctc taattgattg attgtctttc gacattcctg atccaatatt tgtttcatat
    14701 ttatctgttt gattaacatt aggagtagga atgaactttt tcttcacatc tgattgttct
    14761 ttttccgttt cttttgttag cgattctctg tctttaagtg ctgtgtcatt ccgaatagca
    14821 ctattatcaa agttgctgtt aagctctctt gactgacttt caccagatgc tccatctcct
    14881 aattcccgat gaactctgtc tgacacgtcc tcaccactca tttcattcct cagttcttga
    14941 tgagtttgat ctaaagtaat ctcgtcatct tcattctcag gaattgcaac agcaattggc
    15001 gtatgccatt gttgttcgag ttctctattt cgatctgcca caagcgcatc tctcgtctca
    15061 atgatattcc catcctcatc gactaaatcg ccattcacat tatatccatc gctgtgttta
    15121 ccaagtttat taccaaactc atcaacaaga tttccatctt catcaactaa acgtcctttt
    15181 tcgtcaacta aacgtccgtt actatcctga ccaaaatcac catttagcaa cctgcgtcca
    15241 ttttcgtcaa caagatttcc atcttcatca actaagcgac ctttttcatc aattaaacgt
    15301 ccttcgctat ccataccaat attaccatct tcactatctt ccaatggttt accattagta
    15361 tctataaggt ttccatcttc atcgaccaaa cgcccttttt cgtcaataaa gttgccttta
    15421 gcatctttac cgtatttact atcttttaat atttcaccat tttcatcgac aaagtttccg
    15481 ttttcatcaa ccatacgtcc taaatgatca atatattgtt gggaattatt acgtagttga
    15541 tcttgacgaa ctaaatcttt gaaagaggta ttattgattg ttgaaccaac tccgccaccg
    15601 ttgaatgaca ttccttctgg tgtttcagga attactttat cagcaatgga cttagcatca
    15661 gcattgctat ctcccatatt gttcaaacgt tcagccattt tttgcgctcc aactgctcca
    15721 agacctcctg caaccatatc ttttactgag ctgttaccac catcataata gggattttta
    15781 gctccttggc ttttcttgat tgctttagaa acgccgtcca caactcgcac agcatcattt
    15841 ctattaccaa ataataactt agcacgttca tcaaacccaa acgctacttc aagtggtaag
    15901 ccaataagca tattaatcaa attatttact ttttcgcctt ttttaaagac taaaagatat
    15961 cctacaccta aaatcatagc agatcgaaca atatttgcta cgccatcgcc aactaatgta
    16021 ttaggaatga atcccacagc agtatcacca aatgcacgaa taaaagtaat cagaaagata
    16081 ggtaattgta gtccaatcag agatgttgta acaacaccta atgaaattgc catcacacct
    16141 gctcctgatg caagtgatcc tgttagaact acttcccaaa tccgcataaa ttcacgttta
    16201 aatgctttca cgatatttac attgaacatc gcccaagcac atgctaagta aagaactgct
    16261 aaaacgattg attcagcgtt catcgctagc cacgagccaa acttacccat cgctccatga
    16321 ccaactaagg atgctgtacg ccattctgtt tttactgttg acatattctt agcactgcct
    16381 tggattcctg aaggagcgat attatacgca taaaacttag ctcctgatgt atcaagtgcc
    16441 gattggagca ataaagctac cgactgtgtg ctaaaagttg cattgttagc aacgccccaa
    16501 ggttgagtag catcaaagtt atgcgctgtt ccttttccat caggcttgcg attgtcgtct
    16561 gtcacatttt gatttgctga ccaaatatat ccatttaaat tggttggttt cttaattgca
    16621 cttccttctt ttccatcccc taaattatag cctgtccaaa cagcaggcgc tcttcccata
    16681 taggcatcat tttcggcgac attaacatca ccggcataag tattaatatt aaaagtatca
    16741 ttcgatgacc attcttttaa tagagccata ccgactgaat tagaatctag atcattattt
    16801 tgtctggcat aactgctagt attgatcgct cttatcattg cagatttttt agatggttca
    16861 taatctgtat caacgaactt gatttcggat gtaggctttc cgtcaggtac atcaccacca
    16921 gtatcagatg atggagcaag attttgagta gaagcccaaa gtcttgtgtt aatgatgtag
    16981 tcagaaacaa catttgttgg tatatctcca tctttttttg ctgactggat gccgttgata
    17041 taaactccca atagcgatcc tgccactggt aagaatataa acaatacaaa aatacgaaca
    17101 atccattttt caagtactgg tgataatccc ttcgagttaa caccatcttt cgacaataat
    17161 ttcattcctt ggtaacctag tattgctgtg aaaaagagca tagataagct tgctatcgct
    17221 ttaaataatt cattatttaa tcccaaattg ttaagcaagc tagttaatgc tttagatacc
    17281 ggattagata catccgatcc accttctccc caccccataa gagaaaatat attcatactc
    17341 atgaaaaatt ttccaaggag ttcatttatg gattcagcaa tattagaaag gattaaacta
    17401 attgagccga taaaactacc aatcgtccta ccaatacttc ctagaatgga tgatgcttga
    17461 ctggcaatag catttcctga gactgtttca atatatccgt agtaactata agttgctaaa
    17521 gtagatgcta gttgagtacc tgcattaccc cctgcaatcg aattaccttg tttagaaata
    17581 tcagaataag gaaaatcggc actgatacca ccttgtccta acaaattcat ttgtccagtt
    17641 ttagcggcac tatcattaac ttctttatct cccattaaga tacgagcata tagtgtccac
    17701 attccttgtt ctgccggttt actttccgca taagcaacgt tcttatttat aactgtttct
    17761 tgtttgctgt cttgattgtc aggagttgga tcattcattc caaaaggagc gcctaaagta
    17821 actgctaata ctcctccaat aactagacct cttacgaccc atcgttttat tctaagattt
    17881 tgtagtaaat atttcttgaa tttcatagct acgcccctcc aatcgaaaat acaatcttgt
    17941 tttctttact ttcagcaacg gaaggctttg caataatttc agcattagaa tcaccttttc
    18001 cttcaaacgc tccggcttca ctcaacttaa catcgaatat ttttgcgttt ggataagtaa
    18061 ttattgcttc agtaatcgct tcttcaaact cagattcaac taaatgcaag atattccttg
    18121 caccccctga tttagaatcc tcttgtgaag ccatgtcaaa aactaagtgc atggagagat
    18181 cgtctgcata aaaattttga ccatatactc tttcctaggt ggaagacgta agtctatatt
    18241 taaatgtttt cgtactaatt cagcactctt caacatttca ttataagcaa tttccagaag
    18301 agtttgttcg gataaagccc aaaatggaac tattcgtcca aatcggttaa taacttcagg
    18361 ctttagacct tcaccaatca aggcttgttt gatccctgat gcgacttttc ggtattctct
    18421 ttttagttca gtgctatatt cattagaatt ttccttgttt gtaacacgag atagtgagct
    18481 atatctgttt aacgaatcga acatctccgc acctgcattt gttgtcgcaa ataaaattgt
    18541 atttgacaat gaaacggtgt cgtgaacttc tcgatcatcc catcctcttt cagtaaaact
    18601 tatcctacct tcatctaaaa ttgataaaaa ggcatcgagt gtttctacac cagctttctc
    18661 atattcatca cacacaataa tcgcagaagg atcatgcctt acatgagtac ctatgagtcg
    18721 tctaaaacgc attgcatcat ctttggtttt gtagtccggc atattaacta agagaacttt
    18781 attttcatcg ccataaagtc ctcttgccac ggctttagcc attgcagttt taccgacccc
    18841 tgttgatcct gtaaacagag cagttgcttt tggttgcttt cgacctttaa aacgatcaaa
    18901 tccaagcttc atacgtttaa acaacattgt tatagtataa actgctaacg gttgcccttt
    18961 tatggacttt aattcctctt gaagtttttc catatcaaaa tcagaatcta gctgaatatt
    19021 atacttacca aatatttgca atagactttc tcgattataa gcatttccgt ctactcgatc
    19081 ttttgcaatc aaatcctcca ttacggcaat tgatttagcc ggttcggaca aatcctcacg
    19141 ataaagcttg tttgcttgta cgatttcttg aagtaattca tcaggaatcc tttgcgataa
    19201 tttaaaagaa gcctgaggat catctttaac agaggatgta tttagccatt gtctcaaaat
    19261 atcgacgaca acatcgcttt ttagttcatt caattctaac ggttgtaacc gtctccctaa
    19321 ggcatcatct cttttgatat agttttcata ttcttttctt gtagtagcgg taatcaattg
    19381 aagtgattca tttgctaacg gttcttttag cgaatcaccc ccaattttat tgccactccc
    19441 aaaagagcta acaactttat gaaactcgtc aatgaagagg acaaattcat tttctttgtc
    19501 ctcagatttt aaaattcgct catattcttt caatcttgga attaatgttt ctaaacgtgt
    19561 ttggaggaca tcatctcccc caacacgcaa ttgtccgatt gataatttgt atacttgtac
    19621 tttctttcca tcttgtcgct gtctttcagc ccattcactt gcaagtgctg ttttacctgt
    19681 tccggcttca cctaacaaga tagcttgcgg tgtttccggt ctattcaaga tcagtgacaa
    19741 ctcatggagt tcgtcatcac gtcccactaa cttatgtttc ggtggtttca ttggtgtgag
    19801 agcatgatta aattcagttt gaatattctt aaaaaactcg gtactatttt ccatctgttt
    19861 gtgttcactt cctctaaaat aagaataatt tacttctagt cagtcagagt taggtactta
    19921 aatgtcgtct tcatgtctcc aaaagaatct ttggtaaagt cagcattttt gtattgatca
    19981 atcaattttt gtgtatcatt gattgcttta atttcggtct ccattcgact gtctagttga
    20041 cgaatacttt cttgcgaatc tttatcgtca ggattttgtt gtaaacgttc cagatactca
    20101 gcttttgtgg cttcaatttt cttgatgtta gtatttgaag catttaactg atcttctagc
    20161 ttatttacaa cattattctt acttgtaact gctacaactt ttgaataatc aatatcgcca
    20221 tctttggtaa gaaagcttcc ttgatagaca ttagttgaat ctgaatatgg atttattctg
    20281 aaattgatat tatcaggagt attaacaggt tttgcttttt tcccaaaaga aattactcct
    20341 tcattattaa catcattcat agaatattga gaaagtgctt ttgtaactga atctgcttca
    20401 ttcacattga ctttggtatc atcgtcagct gtatcatcac cagaaattag tgatacttgg
    20461 tttgcaataa aaacttgata agctctttca tctaatttac cttttaggaa taagaaagca
    20521 tccccatcag tacttaacat cccatagctc atttcaagct tcttaggacg atctttttct
    20581 tttgttgcca tatataagtt gtagtttttt ccttgcgtag ataacaactt tctagcgttt
    20641 tgcgagtaac cgagttttac tactgttaca tctctgtttt gatctgtcca cacatctgaa
    20701 atagtgatct ctgctcctga tcgagcaaac tccaatgaag agcctatagg tgttgtattg
    20761 ttcacgagat aataattata gtttcctaat tgataaatgt agctacccaa gcctgttaat
    20821 aaaaaaagca ctcctagaaa agttgcaagc ataatgcgta atccgtgacg tgttctctta
    20881 tccttatcac caagcaaccc tccaataata ctgtattgat ctttggtaga tgttgaattg
    20941 acgttttttt ccattagttt gtctgccccc tttcataaaa gagcaaacaa tcagacgttt
    21001 tttcggtaat tctaggttcg ggattttgaa tcatttcggt atattcttcc ccattaatat
    21061 ttaacacaaa aattatcttc ctttcttcgt tcctttcttt tgctctttat tttccaaata
    21121 atcaatgatt tttgctattg taccaagata gtaattcccc tcggctttgt tttttcggat
    21181 tttgctaacc attggagtag gtacaatctc ttcatctctc aattcactga aagatttttt
    21241 acctagatat tttccaataa cagattttaa aaaacgttca aaatctttct cgtaagttgt
    21301 tttcttgcct tttagttcat ggttcatatt gtcaacgact tttgcggttt caataattgt
    21361 tttagttctc agcttaataa tttcatctgg aattttcaat cctcgtaatt tcatcgttgt
    21421 actaactggt aacccatgct ttactgcatc agcaatacta aaacttttta gatcatctag
    21481 taagctctcc atatagttaa caaattcatg ccaattaata gcattcattg tctcacccct
    21541 tcattttttt aaaatgaggt tcgggcgtaa cacatttatg ttattataat atcataataa
    21601 cataaataaa tcaatcagca aatttagata tcccttaaag tatcagcaat tattcaacaa
    21661 gatatttatt ttagctattt cagtcatcat gaaagactaa ttagcaataa aataactaat
    21721 attatccatt tatcagacaa aaagaaaaaa cttatctaat tactctatat taacttttaa
    21781 caaatagttg acttgtccaa aaatgttacc ttcaatctca caaagatatt aagatgtttc
    21841 ctaccaaaac tgatatcacc ggacttttta ttctgtgttg tccaaaagtg ttacctttag
    21901 tcgatcaaca aattaaaaaa aaattgtttt tttcttgact tgtccaaaag tgttacccat
    21961 agttgttaaa atttgtatag attagccatt ctttcaaata ttatttagac tgaaacttgc
    22021 ttacaaaaaa acttcttgca tttattgtcc aaaagtgtta cccatacttt tttaaagaag
    22081 caggttgtat taaaattaca acctgcttct tctcaatctt cttctaacca attatgcatt
    22141 gaaatggttg gcaagtttga ttctggctca ctaaaagtga atctgagccg atcaactctt
    22201 cttcctttct ttgcatagat tttttcataa tcaaaagttt caaatacctg tattccgttt
    22261 tcatcaggag ctaaaaattc ttctttcgcc tgctctagta ttcttttgtc aatatttgtc
    22321 attctataac ttgaaggtat acttaatgct cttctaaaat cttcaacttt gactacccaa
    22381 taaccatttc gccactcttt atttctgtat tgcatgagat gacgatacaa ttcttttgtg
    22441 tagctacttc ttagttttgt aaaattatca agttcaaaac gagtaaagtt tttgccaatt
    22501 gagtttaaga taaattcaaa ttcctcattt gccttaattg taactgtttc cttctgttta
    22561 tctatccgga atttttgaaa aagccacagc tgttcataga cgtctgaatc ttcaaaacgg
    22621 taggttaaag tacctagttt gtcactcaaa gcttttaaca cagaataaaa actgtccttt
    22681 tctcttctgt cgtatttgac caaataacga aagaggttga aatcaaaagt tacttctgct
    22741 gttccttgac gtttcatttt tgataaaata gcccaaaaca catccatttc aacaggctta
    22801 aatcctcgca aagctgttgt attcagacca ttgttataac gcacaattgc atttgtttgt
    22861 tctgatacta aatctacatc actatcaata atcttttcgg taacttcttg agacattgat
    22921 tactctccaa tcttcttttt gcgctccttt aatcatgtta atctggtact aattaaagga
    22981 aacaattttt tctgcttgtt acctaaatta aatcacaact aaaggtaaca gtcaacaaag
    23041 atttgttact aatctaattt tctatttttt cgccttccaa atcaagaaaa ccgaaggtaa
    23101 cgtcttatcc tagtgtgata cctcaaatgt ccacttttgt tacctttgct gtccaaaact
    23161 gttaccctta ctgtccactt ttgttacctt tactgtccaa aagtgttacc tttatacccc
    23221 tttaatactt actctcccaa gagattaaga ctcccctaac agatatatta acagatattt
    23281 aacagatata ttaacagata tttaataaag gaggattact cctctcttat ttcaaaatct
    23341 taaaaataaa aaatcttaaa aaaactaaca ctatctaaga gtttattttg cttgtgtaac
    23401 tttgaataat tgaaaaaaag gaaaaggagg atgcttcagc ttcccctttt atttatattt
    23461 at
//
LOCUS       DAKCAA010000041        23288 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000041 DAKCAA010000000
VERSION     DAKCAA010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.041"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..414
                     /locus_tag="OUE31_001769"
     CDS             <1..414
                     /locus_tag="OUE31_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0222776.1"
                     /translation="KVRVDDRKEVCDDFKMVYQASSKEVALEARGTFAEKWKTSYPKV
                     VESILSNDHLLTFYDFPLAIRKSIYSTNLIESFNKQIKKYSHRKEQFQNEESMERFLV
                     SSFDTYNQKFLGRSHKGFQQAEGELEQMLSQLIEN"
     gene            548..2737
                     /locus_tag="OUE31_001770"
     CDS             548..2737
                     /locus_tag="OUE31_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCU0222777.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            2734..4527
                     /locus_tag="OUE31_001771"
     CDS             2734..4527
                     /locus_tag="OUE31_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCU0222778.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            4727..5041
                     /locus_tag="OUE31_001772"
     CDS             4727..5041
                     /locus_tag="OUE31_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCU0222779.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            5062..5439
                     /locus_tag="OUE31_001773"
     CDS             5062..5439
                     /locus_tag="OUE31_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCU0222780.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            5449..6222
                     /locus_tag="OUE31_001774"
     CDS             5449..6222
                     /locus_tag="OUE31_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222781.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            6244..7647
                     /locus_tag="OUE31_001775"
     CDS             6244..7647
                     /locus_tag="OUE31_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCU0222782.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            7829..9013
                     /locus_tag="OUE31_001776"
     CDS             7829..9013
                     /locus_tag="OUE31_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCU0222783.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            9010..9300
                     /locus_tag="OUE31_001777"
     CDS             9010..9300
                     /locus_tag="OUE31_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222784.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            9297..9518
                     /locus_tag="OUE31_001778"
     CDS             9297..9518
                     /locus_tag="OUE31_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222785.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            9560..10339
                     /locus_tag="OUE31_001779"
     CDS             9560..10339
                     /locus_tag="OUE31_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HCU0222786.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            10406..10900
                     /locus_tag="OUE31_001780"
     CDS             10406..10900
                     /locus_tag="OUE31_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCU0222787.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            10956..11594
                     /locus_tag="OUE31_001781"
     CDS             10956..11594
                     /locus_tag="OUE31_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222788.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            11666..12061
                     /locus_tag="OUE31_001782"
     CDS             11666..12061
                     /locus_tag="OUE31_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCU0222789.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            12045..14498
                     /locus_tag="OUE31_001783"
     CDS             12045..14498
                     /locus_tag="OUE31_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCU0222790.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYLVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            14495..16522
                     /locus_tag="OUE31_001784"
     CDS             14495..16522
                     /locus_tag="OUE31_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222791.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            16519..17541
                     /locus_tag="OUE31_001785"
     CDS             16519..17541
                     /locus_tag="OUE31_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCU0222792.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            17558..18487
                     /locus_tag="OUE31_001786"
     CDS             17558..18487
                     /locus_tag="OUE31_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCU0222793.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            18732..18848
                     /locus_tag="OUE31_001787"
     CDS             18732..18848
                     /locus_tag="OUE31_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HCU0222794.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            18864..19667
                     /locus_tag="OUE31_001788"
     CDS             18864..19667
                     /locus_tag="OUE31_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCU0222795.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            19902..20138
                     /locus_tag="OUE31_001789"
     CDS             19902..20138
                     /locus_tag="OUE31_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222796.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            20145..22097
                     /locus_tag="OUE31_001790"
     CDS             20145..22097
                     /locus_tag="OUE31_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCU0222797.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(22169..22666)
                     /gene="dfrG"
                     /locus_tag="OUE31_001791"
     CDS             complement(22169..22666)
                     /gene="dfrG"
                     /locus_tag="OUE31_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCU0222798.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            22896..>23288
                     /locus_tag="OUE31_001792"
     CDS             22896..>23288
                     /locus_tag="OUE31_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCU0222799.1"
                     /translation="MKYILSFCTPKLNYLLAYIRLYSGVLHLRDSVRVSEKEKIKVTE
                     MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRKKIENPHPLLQTTVE
                     PSKPEQREMLLDALLEISDSDPLLRYYVD"
BASE COUNT         8113 a         3750 c         4414 g         7011 t
ORIGIN      
        1 aaagtgcgtg tcgatgatcg taaggaagtc tgtgatgatt ttaaaatggt gtatcaagcc
       61 tcatctaaag aggtggcgtt ggaagcacgt ggtacttttg cggaaaaatg gaaaaccagc
      121 tatccaaaag tggttgaatc gattctttcg aacgatcact tgctcacttt ctatgatttc
      181 cccttggcca tacgcaagag tatttattct acgaacttga ttgaatcctt taataaacaa
      241 atcaagaaat acagccaccg caaggaacag ttccaaaatg aagagtcgat ggaacgtttc
      301 ttagtctcgt cttttgatac ttacaaccaa aaattcctag gtcgcagtca taaaggtttc
      361 caacaggccg aaggcgagct cgaacaaatg ctaagccaac tgattgagaa ttagaaacaa
      421 tctgcagtag ggaagaatca tttacacaaa attattgacg ctcccttata atgagaactt
      481 ttactaacat aatttatgat aaacttacta tataatcata ttaattaaat agttaggaga
      541 tctgcttatg tttatatcta ctcttcaaat tcgaaatttt agaaattatg aatccgaaat
      601 ctttcgattc gataatgaga caaatactat tataggtgag aatgattcag ggaaaaccaa
      661 tgctcttact gcattgagaa tcttattaga tgatagttat tactatagta gtaaaacact
      721 aaaagaatca gatttttttc atggaattca aaatgggtgg caagggcatt ggattattat
      781 ctctgcgaca tttgaaggaa tcagcgaaga agaatttgac aatgagattt gtgcttccat
      841 ttctttaaat tctgaaagtc aaacaatctt agaagaattg atttcaaatg cagataaagg
      901 tgtaggtagt atttctctat ttattagacc taacaaagct attagaaagc aattatttga
      961 tatttccact gaattagact ctcatcaatt taacgaattt agaaattcta ttcgtctatc
     1021 cgactatgaa ttttactaca catctaaatc aaatctaaat ttctgtatca atgaaaatta
     1081 tgataaattg gtaggaagac tcaatgacaa tatagctagt aatcctgaag aagacgatga
     1141 agctctgttg ggctcaagaa ttgacatgtc agatattttc aagcatattt cggttgttta
     1201 tgttgacgct cttcgagatg ttcttagaga aatgaaaaac aatcgaaacc cagtcaaaag
     1261 aatcatggaa acaattgaat caaaaatatc atcagataat gttgagtcat taaaaacaat
     1321 tatacagcaa ttaaatgaga ctattaccag tgttcctgaa attaggaaaa ttggcgaaaa
     1381 tattaatcgg caactaaata gcataattgg ttcagtgtat tctcctaatc ttcttctttc
     1441 ctcaactatg tcagatgata tgggttcttt agcaaaattt ctttcaatga agccagaaca
     1501 aaatatcgac ttagacttac tagggttagg acatctaaat atgatttatt tagctttgaa
     1561 aatagtcgaa tttgaagcgt gtcgttcaag agaactactt aatattatgt tgattgaaga
     1621 accagaagct catattcatc atcatattca aaaaactctg ttcgaaggat taaatcttca
     1681 aaaaaactat actcagattc tcatgaccac acattctgta catttagctg aagtgtctga
     1741 aatatctcgg atgaatgtat taaaatcgtt taatggcaaa tctatcgtta tgaatccagc
     1801 aaataatctg aactcatttg ctaaagaaaa gttaaaaaag aacaatctaa atctaataaa
     1861 cgcagtagag agatatttag atgttaaaag aaatggattg cttttttcta aaggtgttat
     1921 cttagttgaa ggagatgctg aagaaatact tattcctcaa atagtaaaaa aattatttgg
     1981 tataaactta gacgaacttg gaataggttt gattaatgtt ggtagtactt cgtttgaata
     2041 tatcgctagc ttgtttgacg atgatagaat acagagaaag tgtgctattg taactgattt
     2101 agatgaacag gcaatcccat cagaacatcg attgtataaa agcactgcac aagagaaagg
     2161 tcaagcaaga aaagaaaaat tatcctccct ttttaatgaa aacaattggg ttaattgttt
     2221 ttatgctaat acaacatttg aaattgagtt tttagatgtg aataaagaaa atattctaac
     2281 ttatgtcagt ccaattatag atgacgcatt caaagataaa aaaacaataa ctgcttataa
     2341 agaagaaata caaagtgaac aatatttaga aagaaattta gcgatgttaa aactagccaa
     2401 tcatgttggt aaggggtggt ttgcaattga gttaggtgaa aaaattgact ttttaatcaa
     2461 aattcctaag tatattctta atgctattgc ttttgcatgt caggaaatag tagatctctc
     2521 aatttataaa aaaattctac tccatacaat cgacttgtac gaggaaacta cagaattgtc
     2581 agctttatca gctagtttaa aaacaagtga tacagctgat ttgaatatag caataatttc
     2641 tttattagag tactttggta aagatgagga tgttgtgtat ctaatcaatc agatagaaaa
     2701 ttacacaaaa atactttatg ctgaggtttc aaaatgacaa atatcttcga aaaaatcgta
     2761 aatgatttaa atttagaaca aaaagatgtt gtggaaagtg aagataacct ttatgtaaat
     2821 gcatgtcctg ggagtgggaa aacaagggta cttacaagga aaattgctta ccaagcaatt
     2881 aaacacgatg gatcactaaa aagaataatt gctatcacat acactaatag agctgctgaa
     2941 gaaattaagg aacgcctaag tttacttagt atagatgatg atattaatat ttgggtgggg
     3001 acaatacatc agttttgtct tgaatttatt atttatcctt ttaaaatgaa tctctcaaga
     3061 gtatcaaaag gatttacaat tattgatgat tatactcaaa gagcttacgt cagccaaatt
     3121 aataatatgc tgaatttaaa tctcaaaacg tatgaactga acaaaattga tttgtcactt
     3181 tctcatgatt ttaaaattaa tgaagttcag tatactcaag tttctgaaat gtatcacact
     3241 atgttggaaa aaaataaaga aattgatttt gatatgattt tactagtagc gtataaaatt
     3301 ttaactgtaa acagtaacgt tgcacgtaat attgctagta atataagggc gatttatgtg
     3361 gatgaatttc aagatactag agaattacaa tacaatgtaa tagctaaatt acttcaaaac
     3421 aaccctcaaa ttcagtcaat gtttgttgga gatattgacc aagcaattta tggatcatta
     3481 gatggtatag ctaaatcagt tgaagaacta gaaatgctaa ctagtcacac ttttcaatca
     3541 aagacgctac atggctgtta caggtctaat cagagattag tagacttcta ctctaatttt
     3601 cagagttgtc cttacgagat tgaaagcaga gggaataata aaaacgaccg tggttttata
     3661 agttatgatt gcaaagttac taaggaggat ttacccaaca taataaaaaa tataataaag
     3721 gaaaagattg aaagcggcat tcatgaaaaa gatatttgtg tacttgctcc tcaacactat
     3781 cctctgtttt cactgggtga gtatttaaag aaagaattac cgtattgcaa ttttgatgct
     3841 ataaatatat caccaattaa ggtaaataat catagtttat ttttcaagtt agcaattttg
     3901 tactttactg aatcaggtga aaaggttcga agaagaaagc taattgcaaa cgatatttta
     3961 attatattaa aaaatgaatt tggaatagaa gttaaagatt attttattga cttagattta
     4021 ttacagctaa taaacagtgt gaaaagaatg tatagtggag acgacaacgg tgttgattta
     4081 tacaaatttg ttaccaaaca tatatttgtt aatcttaata ttgacgagaa aaattacccg
     4141 tctattttta agcactatct attttttatt aacgaagtag aagatcggat aaaaaataat
     4201 tcattatcta gtagtgtatc tagttttaag aagatgttta aatctcgaga tggtatcaca
     4261 cttactacag cacataaagt taaaggaaat gagtatgata ctgttatcgc tattaatctt
     4321 ctaaacggga aaattcctca ttggaatgaa atttttaatg tttctgataa aggaattagt
     4381 tcagcgagaa aactactata cgtaatttgt tcaagagcaa aaaataattt atttcttttc
     4441 tcagaggtgg gttattttac gagtaaagga gacttgcttt atcccactca attattagat
     4501 aaaatagaat ttgattataa tatttaaaat acctaggtag tcgttgtttt aaatatagta
     4561 ggaatcggac gctcagtacg gagcgtctat ttttttaccc aattttgaaa ggaagtgaac
     4621 ttatgaaaat aaaaaatcaa gaatcaaaag gtcgctctcc cccctttaaa accatcacac
     4681 aaataagatt cattcaaaca taaaaacaga aaggataggt aaaaatatgg aacttaaata
     4741 tgtcattccc aatatggaaa aaacatttgg acaattagaa tatgctggtg aagggaacat
     4801 tgaacaacgt cgaataaatg gcagaccaac cattctctct cgtagttaca atttatactc
     4861 aacgattcaa cgagcagatg atattgttgt cattcttccc tccgaagctg gcgagaaaca
     4921 ttttgaatcc gacgaaaaag tcaaactcat caacccacat attaccgcag aaggttataa
     4981 aattggcaat cgaggattta ccaattacat tatgcacgca gacgatatgg tgaaagcata
     5041 agaaaggaaa ggtgaaaaaa tatgagatta gcagaaggta ttgtgattga aaaagaccag
     5101 acatttggca cattgaaatt ttccgccttg cgtcgtgagg ttcgtatcca gaatgaagat
     5161 ggtacggttt ccgaagaaat taaagaacgt acctatgact taaaatcaaa aggacaagga
     5221 cgcatgatac aagtcagtat ccccgcttct gttcctttga aagaatttga ctacaacgca
     5281 gaagtggaat taatcaatcc tgtggcagat accgtagcga cggctacttt tcgaggggca
     5341 gacgttgatt ggtacgtgaa agcagacgat cttgtattaa aaggacagac aaaacctcat
     5401 cagaaatata aaaaagaagc gtccgaaagt gaaaaatagg tgttgcttat gacaaacaca
     5461 ccattgattt tgaaagaaat tccgaaggat gaagccattt cttttattcg gcaataccat
     5521 tattcaaaga tactccctag attgtgtaaa tactttctag ggattttttc agaagaaaaa
     5581 ttattaggcg ttgtggaatt aggctggggt acgcaacccc tacaaaccat acgcaaactc
     5641 tttcccgaca gttcccttca aaccacagat tatttagaaa ttggaaagat gtgttttctt
     5701 ccagaaatga atcaaaccaa ttattttggc agtcaagctc tttcagctct aattaagtgg
     5761 ttgaaagaac atacggactg tcatttttta tatacactgg cagatggaat tgagggaaaa
     5821 tgtggctatg tctatcaagc gtccaacttc ttttactgcg ggtatttcaa gacaagtgtc
     5881 tatcgtgata agcagtcatg ggaaaagata caccctcgaa gtgctcgcct tttattagag
     5941 gaaaatgctc gctttgaaca ggtagagaaa aagcattggc tttcccaggc attttgcgaa
     6001 tacaaaggga ttgagaaaat caatggacgc atgtttcgct atctctatcc gttgacaaaa
     6061 gaagcgaaaa aactgttagg acacactctc tatcgacgtc attattatcc gaaagaaaaa
     6121 aatttacgct ttgaaaagcg aatcgcttat cagaaatatg aagccatttc tcaaccaact
     6181 tttgataaac aggctcgtat ctacaataca caattatttt gataggtgga aaggaggatt
     6241 tttatgccat tgcttcatga cagaggagag cgaatcaaag ccaacgataa gcacttggtc
     6301 tatcattttg tactaatttc attgctggta gtttttctag tcgtcctact cccttttcat
     6361 tggagagcgt tacaatcggt gaactggcaa gcagttcagt tagatacatt tttctatcaa
     6421 cttcatacgc catacttttg gagcagtatt ctcactgctc tttttgtatg cggacttatc
     6481 agctggcttt attatcacta tcgtatagat tctataaaac agttagagca ccgtcaaaag
     6541 ttagctcgta tgattttaga aaatcattgg tatgaagccg aagaaactca atcagaggga
     6601 ttctttaaag atttacccag caagaaaacc aaacaacgaa tccgccattt tcctaaaata
     6661 tattatcgaa tgaaagatgg actaatccat attcatgtag aaatcacctt agggaaatat
     6721 caagatcagc ttttgcacct agaaaacaaa ctagaaacag gattgtattg tgaattagtg
     6781 gaaaaaacgt tgaaagattc ttatgtagag tatgtcctac tttatgatac tattggcaat
     6841 cgaattggca ttgaagacgt ggtagctcaa gatggacgtg tcaaattgat ggaatcggtc
     6901 tattgggagt tcgattctct ccctcacatg ttaattgctg ggggcactgg tagtggaaaa
     6961 tcctatttta ttctcacatt gattgaatct ctcctgcata caaatgcaaa gctttatatt
     7021 cttgacccta aaaatgctga tttggcagac ttaggggcgg tcatgaataa tgtctattac
     7081 cgtaaagaag atatgttggc atgtatcaat caattttacg aagatatgat tgatcgcagt
     7141 gaaaccatga aacaacaccc taactataaa acaggagaaa attatgctta tcttggtttg
     7201 tctgccaatt ttcttatttt tgatgaatat gtggcaatga tggatatgct aggtcgtgaa
     7261 agtaccaccg ttattcataa actcaaacaa attgtaatgt taggacgaca agcaggcttc
     7321 tttttaattc ttgcctgtca acgtccagac gcaaaatatt ttagtgatgg gattcgggac
     7381 aactttaact tccgtgtggc tttgggtcgt atgtctgaaa tgggctttgg tatgatgttc
     7441 ggaagcgata cacaaaaaca atttttctta aaacccatca agggaagagg ttacgtggat
     7501 acaggaaaaa gtgtgattag tgagttttat acaccccttg taccaaaaag gtacgatttc
     7561 ttaggagaaa taggaaaagt cattcaaaaa aagcaatctg agcctgtacc gcacgaagtg
     7621 aaaggtacag gttcagactt gctttgattg gtgtggcgtt agccacgcca atcctttagc
     7681 cccctctatc taacaggggg gcacaaatac aactgaaaac aggcaattct catcaaccaa
     7741 tgttgatggt acaaaggatt gcggaaaata tgaaaggtgt aaactcaagg gtcatagttt
     7801 acatcttttt tagattggag gtttgcgaat ggaaaacgaa aaaatttgga ttaaggaatt
     7861 gaaagaaaag cgactggctt atggcgtttc tcaaaataaa ctggcggttg cttctcatat
     7921 taccagacct tacctatcgg atattgaaac aggcaaggca gtccctactc aacaggtgaa
     7981 agaagattta ctgaacgctt tggaacgctt caatcccgat aacccattgg agatgttatt
     8041 cgactatgta cggattcgat tccctaccaa tgatgtggct caaattatcg gtgaggtttt
     8101 acgtttgaat atggattata tgctacacga agactttggc tattattctt atcccgaaca
     8161 ctatcgtttc ggtgatattg ttgtcctagt ctctcatgat gtaagtaaag gtgttttatt
     8221 agaactgaaa ggaaaaggct gtcggcaatt tgaaaacttt ctattggctc aacatcggag
     8281 ctggtatgat ttctttcaag attgcatgga acataaaggt attttcaaac gcttggattt
     8341 agctatcaac gataaaacag ggattttgaa tattccagat ttggcaaaga aatgtaaaca
     8401 ggaagaatgc atttccgtct ttcgaagctt taaaaattat cgcagtggtg aattggttca
     8461 ccgtgatgaa aaaccataca tgggaaacac actttatatt ggctcattaa aaagtgaagt
     8521 ctatttctgt atatatgaga aagattatga gcaatacgtg aaaaatgatg ttcccttaga
     8581 agacgcagaa gtaaagaatc ggtttgaaat tcggttaaaa aatgaccgag ccacccaagc
     8641 catgaaagat ttattggcac atcaacaggc ggaaaaaaca gcctttgaaa ttatcaatcg
     8701 ctatatccgc tttgcagata aagacgacac taaacgtcgg agtgattgga aaactaatga
     8761 acgttgggaa tggtttatcg gtaaaaatcg tggagcatta cgcctaacca cacagccaga
     8821 gccttattct tttgaacgaa cattgaactg gttacatcat caagtcgccc ctacattaaa
     8881 aatcgcaagc attttagatg ttctcaacgg tacaaccatt atctccacca tgattcagga
     8941 agccaaactg acagaaaaac atgagaaatt aattgaacaa caacatctag ccatggagga
     9001 tttgattaca tgagcctttt aacaaaagaa ttaaagaagt tagggtttca gtgtggcatt
     9061 gagtttcaag cgtatataca aaatacaggg aaatatacgt ctctcattat tgagggaaaa
     9121 cggcaagctg gtgataccat ctatacctat gatttttaca aggtgagatt ttataataat
     9181 tataccaatc gagtaaccgt ctatggagag catttaaccc cttttcaatt attaaggcgt
     9241 gtaaaaagct atatctatta tcgagaaaaa tatcttaagg aaaggaggac aatcacatga
     9301 attttgggca gaatttgtac aactggttct tggataatgc acagtcattg gtattgttag
     9361 cgattgttgt cattggactg tttttaggtt ttaaacgaga attttcaaaa ctcattggct
     9421 tcttgattat tgctctaatc gccgtcggac ttgtgttcaa tgcagctggc gtgaaagatg
     9481 tgttattaaa cttatttaac cgaatcattg gtgcttaaca gatatttttc atgataaaat
     9541 aggaagtata tattttgtta tgaaaggatt tatgaatatg tttacaaatg atcaatttaa
     9601 atctctttta attaaaacat tagaaagaaa gagctcttca aattattatg aaggaggtaa
     9661 cgagattgtt tctaaaatga aaatatcaga ggtaacttta gatgagactg acgattttac
     9721 ttattataaa ggatataaaa agggctggaa tacgctttgc acatatctta aaataagagt
     9781 tccttttgat gatttagact tttttgaaag tcataaagat ttgattaccc agacagcaag
     9841 ctccatatat gataaacaag gtgataatgt attagtggat actattttag taccacttcc
     9901 agagaattac gaagtaatta actttagtca gttgaaaatt agtgatgtgg tttcacaagc
     9961 tattgaagac gctgagtctt ttatgagtaa tggtgaatat caacgtgcct ttgacagagt
    10021 tcacactgct tttcatggat atttaattga aatactaaaa aaatatgaaa ttacagttcc
    10081 tagagacgaa aatctatcta aattatatag taggatacaa caattaattg aaaaagaaat
    10141 tcaacctact gaacttgctg atatagtgaa gacaacgata aggtcatcaa atggaatgat
    10201 tagctctctt aatgaagcaa gaaataggca ttcacttgca caccctaata caaatattat
    10261 tggaaagaga gaagcaaaac taataatagg tatttcaagt acagttacag attatattag
    10321 cggatacctt gataagtagc gtcattaact gattgctact ttttttatga ctatttttat
    10381 aaaaaggatg tgataagaat tggaaatgaa agtctatgtg gcaaatttag gacggtataa
    10441 tgaaggtgaa ttagtcggag catggtttac tccaccaatt gatgaggaag aaatggcaga
    10501 aagaatcggt ttaaatgagg actacgaaga atatgcaata catgattttg agcttccttt
    10561 tgatgtggac gaatacacgc cgattagtga aatcaaccgt ctatgtgaag ccattcaaga
    10621 aatcgaaggt acacctattt ataatgaact caaagaaatt caaggcatgt ggtttagtag
    10681 cttggaagaa ttactggaaa acaaagagga tattcattgt tatagtgatt gtgattcgat
    10741 ggaagatgtc gcccgttatt acgtggaaga aacaggacag cttggtgaag tcccttccaa
    10801 tttacaaaat tatattgact accaatcttt gggacgtgat atggaaatag agggtaatta
    10861 cctagttacc tctcatgggg tatttgaata ttgtcagtaa gtttaacaat ccgtgttata
    10921 attaaattaa taaatagcac ggagaggtat aaattatggt aaatgtattt gaaaatctta
    10981 aactattaaa actagacatg aaagataaag gctgggtgat agattccttt tactttcgtt
    11041 acaaacagca aaattatatt gtacttgtta agctatttga aaaagaggaa aaagttccag
    11101 aatatgctct gttaaaacta gaatttttaa aggaaaacga tttttcagat atgctagctg
    11161 tctatgctaa ttcggtaaaa ttatatacag acacgaaaac aataagagaa tattttggta
    11221 tcgaatacag tagtaacttg ggagatgttt tatttcaatt tagccaaact cttgctcgat
    11281 ttattccgac agaagttagt gagaagaaaa atgaagacca aaaagaagcc atgtgtttct
    11341 cattaagtca aagtgattca gaagatccca gaaaaaaata ttgtttttca gttagaagaa
    11401 atcctttaaa gggaaatggt gagctgggaa aacgaagtcc ttttaatgac aataaaacga
    11461 gattgtatag acccagctta tatgaacgat tagggtcaga taccaattta agtttcagat
    11521 attcaatgaa tccagatgat gaagaaactg atgaaggtat tattgcaaaa tggacaaaaa
    11581 ataaaattga atagttaaag cattgaaaga gcaatcacct attttgattg ttctttttct
    11641 atttttacgg aaaggacgtg aagacatgaa aaaaataaga agttacacca gtatttggtc
    11701 agtagaaaaa gtgatttatg cgattaatga tttacaactc cctttcccaa ttacctttac
    11761 gcaaatgaca tggtttatcg tttctttgtt tgtcgtcata ctctttggca gtttaccacc
    11821 actttctctg attgacggag cactactcaa atacttaggg attcccattg ttctcactgg
    11881 gttcatgtgc caaaagacct ttgacggaaa gaaaccctat ggatttctaa agtctatcat
    11941 tacctatgct ctacgcccta aagtaaccta cgctggcaaa caaatacgat taaaaaaaga
    12001 aacaatgaat gaatcgatta cgattgtaag gagtgaacaa ctagatggca tatccgatta
    12061 aatatatgga agataatctc gtatttaatc atgatggcga agtattcgct tattatgaat
    12121 taattcccta taattacagt tttttaagtt ccgatgaaaa aattcaagtt catgataatt
    12181 tctgtcaatt gattgcccaa aatcgtgatg gcaagattca tgctctgcaa ctagcaaccg
    12241 aatcaagtat tcgagccaca caggaacaat cgaaaaaaga aatcactgga cgattaaaag
    12301 agatagctta cgaaaaaata gatgaacaga ccgaagcgtt aatttctatg attggtgaca
    12361 atcaagtaga ctatcgcttt tttattggtt ttaaactcta cctcaatgaa caggaagtat
    12421 ccgtaaaaaa tgttgggaaa gaaattcaaa aagcatttgc ggaattcttt catggtgtga
    12481 atcacaaatt aatgggcgat tttgtttcta tgcctatggc ggaaatcgaa cgcttttcta
    12541 agatggaaca gttgttagaa agtaaattat ccagacgctt tcagattcgt aaattggaga
    12601 aagatgattt tggttatatt attgaacatc tttacgggca aacaggtgtc ccttttgatg
    12661 actacgacta ccatttaccg aaacgatacg aagataaaaa agtgttggta aagaaatacg
    12721 atattctcaa acccactcgc tgtttaatcg aagaaaatca acgctattta cggattgaac
    12781 aggaagatac cactacttat gtggcgtatt ttacaattaa tagtattgtt ggtgaattgg
    12841 atttccctaa tagtgaaatt ttttattacc agcaacagca gtttactttc cccgttgata
    12901 ccagtatgaa tgttgaaatt gtcgccaata aaaaagcctt atctaccgtt cgcaataaaa
    12961 agaaagaact gaaagattta gatagccacg catgggaaag cgacaacgaa accagtacta
    13021 atgtggtgga cgctttagaa tctgtcgatg aattagaaag taatttagac caaaccaaag
    13081 aatctatgta caaactaagc tatgtggtac gggtatcagc aaagaatttg gacgagctga
    13141 aacaacgttg tgatgaagta aaagattttt atgatgatct gtctatcaaa ttagtacgac
    13201 cttttggcga tatgctaggc ttgcataatg aatttattcc ctcaagcaag cgatatatca
    13261 atgactatat tcaatatgtc acgtcggatt ttttggctgg tcttggtttc ggtgctacac
    13321 aaatgattgg tgaaaattct ggtatttacg tcggttacaa tctcgataca ggcagaaata
    13381 tttatctcca acctagcctt gcaagtcaag gaattaaagg ctctgtaaca aatgcattag
    13441 cgtccgcttt tattggttca ttaggtggcg gaaaatcatt ctctaacaat atgctggtct
    13501 attattcagt actctttggc ggacaggcaa ccattgttga cccaaaagct gaacgtggtg
    13561 aatggaaaga aaccttacct gatattgccc atgaaatcaa tattgttaat ctcacgagtg
    13621 agaacgacaa taaagggtta cttgaccctt atgtgatttt aaaactcccg aaagattcag
    13681 aaagccttgc cattgatatt ctcacgttct taacaggtat ttccagccga gatagcgaga
    13741 agtttcctgt cctgcgtaaa gctattcgga gtgtaactca aagcaaacaa cgagggttgt
    13801 tattggtgat tgatgaattg cgaaaagaag atacgcccat cagcaatagt attgctgacc
    13861 atatcgaaag ctttgtcgat tatgattttg cccatctgtt attcagtgat ggcagtgtca
    13921 cccaatccat tagcttggaa aaacaactca atattattca agtggcagat ttggtcttac
    13981 ccgattccaa tagctctttt gaagaataca ctaccatgga attattaagt gtggcaatgc
    14041 tgattgtcat tagtaccttt gctttagact ttatccactc tgaccgttcc atttttaaaa
    14101 ttgttgacct tgatgaggct tggagttttt tacaagtggc acaaggaaaa gctctatcta
    14161 tgcgattggt tcgagcagga cgtgccatga atgcaggggt ctatctcgtt actcaaaacg
    14221 cggacgattt actagatgaa aagatgaaga ataatattgg cttgaaattt gcctttcgtt
    14281 ccactgacct agtggaaatc aaaaagacct tagaattttt tggtgtggac aaggaagatg
    14341 aaaacaatca gaaacgctta cgtgaattag aaaatggaca atgtttagtt tcagacatct
    14401 atggtcgtgt aggggttatg cagtttcacc cgatttttga agagttgctt catgcctttg
    14461 ataccagacc gcctgtgcga aatgaggtgg aagaatgaca caaaaacaaa agaaatttct
    14521 tcactatagt tggataacgc tcctttgtgt gggcgttatt ttacttttat taggcacgct
    14581 gggcaatgca gtacaagcga caggcttagt tgatgaaacc attgatacaa gcaatgaata
    14641 ctccaagtat ggtttgaatc aatatcagct tgattattat gtggacaata gctggggctg
    14701 gcttccatgg aattggagtg atggcatagg acaatcggtg atgtatggat tgtatgccat
    14761 tactaatttt atttggacaa tttctcttta tctatcgaac gccacaggtt atttggtgaa
    14821 agaagcctat gccttagatt tcattagtca aacatcccaa gcaattggcg aaaacatgca
    14881 gacgattgca ggcattacac cgaatggctt ttccagttca gggttttatg tcggtttcct
    14941 ccttcttttt attctcattg ttggaatcta tgttgcctat acaggattgg ttaagcgaga
    15001 aacgacgaaa gtgatacgag ctgttttaaa ctttgtcgtg gtgtttattc tatcggcttc
    15061 ctttattgcg tatgcacccg attatattgc gaaaatcaat gatttttcca aagatgtcag
    15121 taccgccagt ctgaatattg ggacaaaaat tgttcttcct aacacggata gtcaagggaa
    15181 agacagtgtg gacatgatac gtgacagctt attctctgtt caagtaaagc aaccatggct
    15241 attgcttcaa tatggctcca ctgatgtaga agcgttaggg gaagaacgtg tggaaagttt
    15301 attgtctacc agtccagata caaacaatgg tgaagataga gaaaatgtag tgattgaaga
    15361 aattgaagat catgacaata cctatttaac cctaccgaag acgatttcca gattaggaac
    15421 agtcttcttt ttgtttgtat tcaatattgg tatctcgatt tttgttttcc ttctaacagg
    15481 aatcatgatt ttttcgcaag tgctatttat tattttcgct atgtttttgc caatcagttt
    15541 cctattaagt atgttgccga gttttgatgg catgggcagg catgccatta ccaagttatt
    15601 taatgtgatt atgacaaggg ctggtattac cttgattatt accgttgcct ttagtatttc
    15661 cactatgctt tattcgctgt cagcaagttc tccctttttc atgattatgt ttttacaaat
    15721 tgtgaccttt gcagggattt attttaaact gggcgattta atgagcctat tcactttaca
    15781 aagcaacgac tctcaaaaca tgggcagaca agtgtttcgc agacctcgtc aaatgatgaa
    15841 tcgacaaacc agaagatttc aacgcagtat gagtaagatt tttcgtggaa aagcagggtc
    15901 aacgaagcaa aagacaatga caacaaagca gaatcaaacc aataaagcta accatactcg
    15961 tcaaaatgaa cggactacac caaagaaaga aacagcactt tccaatgtga aaaagcaaca
    16021 aggcggtatc gggcaacgat taggtgaaaa gacagcccat gtattggaca cgaaaaatcg
    16081 tctagtcaat aaaagaaagc aggcaaaaca acagatacag gcgacaccaa cccatgtcaa
    16141 atatgccctt catcaaggaa aagagaatgt cactcataat gtaacagact ttaaacaatc
    16201 tatggcagat accaaagctc aacgcaaaca acagcgtatg aaccagcagg agcaaaaacg
    16261 aaagaacatt gctcaaaagc gtttggagct ggataaagca aaagaaaaaa gacgaaaaga
    16321 aaacccatca tctcctgttc agaataacca gcagcatgtt cgcaagcgtc agcaaaccgt
    16381 cacgcctgtt ttgtcacaaa acactaaacg tgaaaatcat cagcgaccat tgaaaaaaga
    16441 gcaaaaacaa aagacaccac cgaagcaatt caatcagagg aagctaaata aaagaacgga
    16501 taagcgagga caacaaacat gaagctaaaa ataacagtga tttgtagtgt ggtcttctct
    16561 ctcttctttt ttctcttatt attcctagtc attttctttg cagatgatac ggacagtggc
    16621 gaaaacaaca aggattcttc tattccacaa ggcggtgtga ccgtttcacc agaagtgttg
    16681 gcacaccgtc cgttgattga aaaatatggt aaggaatatg ggattgaaga ctatgtttct
    16741 tatatcttag ccattatgca agtggaatcg ggcggtacag cagaagatgt tatgcaaagt
    16801 tccgaatctt tgggtttacc gcccaacagt ttgagtaccg aagagtccat caaacaaggg
    16861 gttaaatatt tcagtgaatt attaaccagt gcagaacaac aaggagtgga tatagattct
    16921 gttatccaat cttataatta tggcggtggc tttttaaatt atgtgaggag tcatgggaaa
    16981 aaatatacct atgaattagc cgaacagttt tctaaagaga agtcgggtgg tcaaaaagca
    17041 gactatccca atcctatagc catacctgtg aatggtggtt ggcgatataa ctatggaaat
    17101 cagttttatg ttcagttggt ttcacaatac ctaaccgaca cttccccaac agaatttgat
    17161 gatgaaaccg tgcaagtcat tatggacgaa gccttgaaat acgaagggtt tccctatgtc
    17221 tttggagggg cgtcgcctac cacctctttt gattgtagtg gcttaataca atgggtgtat
    17281 gacaaagctg gcatttctct ccctcgtgtc gcccaagatc agtatgacgc tacgcaagaa
    17341 atctctatgg aagaagccca agcaggcgac cttatcttct ttcattcaac ctataatgca
    17401 ggcacatatg tgactcatgt ggcgatatat ttagagggaa atcgctttta tcatgcaggc
    17461 gacccaatcg gttatggcga cttaagcagt cgttattggc aagaccatct gattggggct
    17521 agacgtgtta ttcataacta agaaaggaat gaatcaaatg attataaaaa tcgagcgaaa
    17581 agaaaagaag gagaaaccaa agaaatctaa aaaaccgagc aagcaaagaa aagttccgat
    17641 gattaaagtt ggcacgcata agaaattaac ctttgtttta tgggttttat tgattggtag
    17701 tgtcggattt ggaatctata aaaattttac tgccattgac actcatactg tccgtgaaac
    17761 agaaatcatt aaacagcaga ttgtcgatac caaccaagta gaaagttttg tgaaatcctt
    17821 tgcgaaagac tacttttcgt ggcaacaatc ccaagaagcc attgataaac gaaatgaaaa
    17881 attgacccat tatttgacgg aagaattgca ggtattaaat gaagaaatga ttcgtaagga
    17941 tattcctact agttctagtg tgaacgatat acaggtgtgg caggtttctc aagtgaatga
    18001 gaacaccttt gaggtactgt tttctgttga acaagttatt accgaagaca aagacaagga
    18061 aactatatcg tctagctttc atgtggttgt ccatatagat gaatcagata atatggttat
    18121 tatcaaaaat ccgacaatga gtaagaaacc tcaaaaatcg gactaccaac ccaaacagct
    18181 agaaagtgac catacagtag atacagaaac gatggacgaa atcactagct ttttagaaac
    18241 gttcttccag ctctatccta ccgccacaga aaaagaattg acttactatg taagtaatca
    18301 tgtgttacct atgattaaca aggaatatgt tttcgaggaa ttggtgaatc ctatctttac
    18361 cagaaaagat aaccaagtaa tcgtgaatgt cgctgtgaaa tatttagatc aagaaacaaa
    18421 ggcaacccaa atctcgcaat ttgagttgat attagaaaaa caagataatt ggaagattgt
    18481 aaaataacaa atattggtac atgattacag atactttgta atcatgtact ctttttgata
    18541 aaaaattgga gattccttta caaatatgct cttacgtgct attatttaag tgactattta
    18601 aaaggagtta ataaatatgc ggcaaggtat tcttaaataa actgtcaatt tgatagcggg
    18661 aacaaataat tagatgtcct tttttaggag ggcttagttt tttgtaccca gtttaagaat
    18721 acctttatca tgtgattcta aagtatccag agaatatctg tatgctttgt atacctatgg
    18781 ttatgcataa aaatcccagt gataaaagta tttatcactg ggatttttat gcccttttgg
    18841 gtttttgaat ggaggaaaat cacatgaaaa ttattaatat tggagtttta gctcatgttg
    18901 atgcaggaaa aactacctta acagaaagct tattatataa cagtggagcg attacagaat
    18961 taggaagcgt ggacaaaggt acaacgagga cggataatac gcttttagaa cgtcagagag
    19021 gaattacaat tcagacagga ataacctctt ttcagtggga aaatacgaag gtgaacatca
    19081 tagacacgcc aggacatatg gatttcttag cagaagtata tcgttcatta tcagttttag
    19141 atggggcaat tctactgatt tctgcaaaag atggcgtaca agcacaaact cgtatattat
    19201 ttcatgcact taggaaaatg gggattccca caatcttttt tatcaataag attgaccaaa
    19261 atggaattga tttatcaacg gtttatcagg atattaaaga gaaactttct gccgaaattg
    19321 taatcaaaca gaaggtagaa ctgtatccta atatgtgtgt gacgaacttt accgaatctg
    19381 aacaatggga tacggtaata gagggaaacg atgacctttt agagaaatat atgtccggta
    19441 aatcattaga agcattggaa ctcgaacaag aggaaagcat aagatttcag aattgttctc
    19501 tgttccctct ttatcatgga agtgcaaaaa gtaatatagg gattgataac cttatagaag
    19561 ttattactaa taaattttat tcatcaacac atcgaggtcc gtctgaactt tgcggaaatg
    19621 ttttcaaaat tgaatataca aaaaaaagac aacgtcttgc atattaagta gttcagtttt
    19681 ggagtacaaa aagtgaaaat gtaaacctaa atgagtatca aattgcaact gaatttgata
    19741 ctcgtttttt attgttaaat caacgtttgt tgttaattta caccacaaaa tgtaagttaa
    19801 aatgtatata aaaatgcgaa cgtgaaataa ttattgtagg aatgcaaatt ggtgtgttaa
    19861 aatggttaca atttactaag caaaaagggg tgcattttcc tatgcaattt cttgagccaa
    19921 aaaataagaa cgctaagtct gtggattggg aaatatcaga gcaagtaagg gtgatagtta
    19981 agcaatacgc tgaatatgca gagcgtactg aaagcgaagc agtggatgaa ttcttattga
    20041 acattttaga cgataagaag tttattgaat ggattgccaa caagcgaagt aataagcgga
    20101 ttgttgaaaa aatgggtatc aaagatagag tgggttgata gacaatgacc aagcttaaaa
    20161 gattagccac gaaggaagat gaaattgtag atgttaaaat tccgatttca aacgaagaat
    20221 taaaagatag ggctaaacaa tatgatttat taactccaaa acgatttgca acaaggtata
    20281 acaaaatgtt gttcttgcca acgtctttta aatggaacgg ttctgaatat cccattcaat
    20341 ataattactg catcaatccg ttttgttgta attttgggaa agaacagcac aaattcaaag
    20401 atgtaaaagg gaaaccaagt cgatataaaa tgactggtag ttccaaagat aaaggtcata
    20461 aaggtatgta ctgcaatgac aatcctattg gcagaggtgt atcgcaaaac tgtacagtaa
    20521 cccctttatc taattggtct gttgttgaag aaattaaacg ccttatagaa atcaatagca
    20581 tccaagatgt tgagccagat tatcaatttc ataaagaagg ctgctcggaa gaagaatcaa
    20641 ccccattcaa tgagccgaag caattttaca aaagggggaa aagtaggggc aaatctcaac
    20701 gctatcaatg taaggcgtgt aagaagttca ctaatgttct accaaaaaga gaagaaacca
    20761 ctacttatca ccaacaaaag aacaccattc ttccaatgtt cgctaagatg gttgttggaa
    20821 gggtttcagt cagtcgtact tgtgatattt taggaattgg agttggaacc tactatcata
    20881 agctggagtg gctgtatagg cgttgtttgg agtttttaga acgatatgag acacaacccc
    20941 ttcaaacaaa gaaatttaac gagatgtggc ttaatacgga caagatgcac tactacctaa
    21001 ataacgtccg taagaaagga caaggttcaa agaaatatac ggggtttgaa gaccttaata
    21061 tgcaaacgta tatagttgta tctgctgagg tcttatcaag atatgtgttc cgttctgatg
    21121 ttgcctatga ttggaatatt tcaatggatg aattaaatga agatacaaga aaattcaaag
    21181 aagaccatct caatactttt agtcgtaaaa atgataggtt agattggtct tattatccac
    21241 aagaaccatc cgctaacgat agcgaaaata ggaatgctta tcttcacgaa ttagggaaaa
    21301 ttactaatag gagtagattt gtcgatggtt taaatgttga tgctccttat actacaactg
    21361 ctcactattg gttaattaaa caaatggtta atgccgacga atggcgaatg attagtgatg
    21421 atgacttctc tattagaaac gccttttata gagtattcac gaaagaatta aggttgagcg
    21481 atgcacatca ttttatttgc caagttaaca agacgaaaag cagaaaacaa tgcttaaaag
    21541 aattcggaca agcaaaagca gaactgctcg attggggaga tatcagagga ttcaaaacaa
    21601 agtttctacg gactttggca tctcattatc taactgaatt actaacaagt catcaattcc
    21661 acgaagaggc tattagtaaa gatggagaaa gatatcgcaa atatgccgat aaccctatca
    21721 aacatccatt agccactaag gataaaggat tttattcagt tgattgtaga acggatttat
    21781 ctgctctgga accaaacgaa atcgcaaaga tgctattaaa tgttaatgac cattcgacca
    21841 atagctttat tcaacagata agacgttata tatcatctct tgaaagacca ttaacaacag
    21901 ctcgtggtga taagaagagc tatatttacg ctaacttcaa tccgaagtat gctcaatttg
    21961 cgattacaat tctaagaact tactacaact tttgtcgccc ttttaaatca gcggataaaa
    22021 aggttttgac acctgctcaa agattaggga ttacagataa acaatttgat tggaaagata
    22081 taatttattt caaatgacaa aaagagcttg gagtaatccc aagctcttgt gctttatctt
    22141 tactgttctt cttcaattaa cgcacccgtt aactcaataa gttttttctt tcatatacat
    22201 gaaaatagta gttatacgga tttttatcat tctttatccc tttttgggca aatacctcat
    22261 tccattcctc ataattcact tctggaaaaa aagtatctcc ttcgaattca tgatgtattt
    22321 ttgtgatgta cattttctca acataaggga aaaacaaatt ataaatctgt tctcctccga
    22381 aaataaaaat ttcttcttcg tttttacata actcaaaaac atcttctatt gaatgaacaa
    22441 tttcacaacc attaaaggta aaccccttat ctctcgtcag aataatattt cttctgtcag
    22501 gtaaggctct tccgattgat tcaaggttct tcctacctaa tattatcgga tgtccctttg
    22561 tagtattttt aacatattcc cagtccttgg gaatcctcca aggaatgtca ttctctttgc
    22621 caatcactct attcttatcc atcgcagcaa tcaaagaaac tttcatttat aacacagcct
    22681 ttttaactaa tttaccatct aatttcttat ttctatcaaa aaaccttttc tcattatcct
    22741 gcccgttagt tgaataagca attttttcta taagttatat tatcataata ccacaaaatc
    22801 acaaattttc attcaattat cattttcaat tgcattttat aaatcatttt gtatgtaatt
    22861 tggtatgtaa gttaaaatga aaaaagtagt ccattttgaa gtacattttg tcattttgta
    22921 ctccaaaact gaactactta cttgcatata tacgccttta tagtggagta ctacatttac
    22981 gagattcggt tagagtatca gaaaaagaaa aaataaaagt tacagaaatg tatacttcaa
    23041 taaatggtga attatgtaag attgatagag cttattctgg agaaattgtt attttgcaaa
    23101 atgagttttt gaagttaaat agtgttcttg gagatacaaa actattgcca cagagaaaaa
    23161 agattgaaaa tccgcaccct ctactacaaa caactgttga accgagtaaa cctgaacaga
    23221 gagaaatgtt gcttgatgcc cttttggaaa tctcagatag tgatccgctt ctacgatatt
    23281 acgtggat
//
LOCUS       DAKCAA010000042        22950 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000042 DAKCAA010000000
VERSION     DAKCAA010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.042"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            227..370
                     /locus_tag="OUE31_001793"
     CDS             227..370
                     /locus_tag="OUE31_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HCU0222800.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            948..2531
                     /locus_tag="OUE31_001794"
     CDS             948..2531
                     /locus_tag="OUE31_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCU0222801.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(2968..4152)
                     /locus_tag="OUE31_001795"
     CDS             complement(2968..4152)
                     /locus_tag="OUE31_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HCU0222802.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(4177..5184)
                     /locus_tag="OUE31_001796"
     CDS             complement(4177..5184)
                     /locus_tag="OUE31_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCU0222803.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            complement(5356..5715)
                     /locus_tag="OUE31_001797"
     CDS             complement(5356..5715)
                     /locus_tag="OUE31_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222804.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            complement(5687..6058)
                     /locus_tag="OUE31_001798"
     CDS             complement(5687..6058)
                     /locus_tag="OUE31_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HCU0222805.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            complement(6075..6377)
                     /locus_tag="OUE31_001799"
     CDS             complement(6075..6377)
                     /locus_tag="OUE31_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222806.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            complement(6394..6864)
                     /locus_tag="OUE31_001800"
     CDS             complement(6394..6864)
                     /locus_tag="OUE31_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HCU0222807.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            complement(6839..7117)
                     /locus_tag="OUE31_001801"
     CDS             complement(6839..7117)
                     /locus_tag="OUE31_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCU0222808.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            complement(7114..8163)
                     /locus_tag="OUE31_001802"
     CDS             complement(7114..8163)
                     /locus_tag="OUE31_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HCU0222809.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            complement(8120..9049)
                     /gene="tadA"
                     /locus_tag="OUE31_001803"
     CDS             complement(8120..9049)
                     /gene="tadA"
                     /locus_tag="OUE31_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HCU0222810.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            9181..10935
                     /gene="ade"
                     /locus_tag="OUE31_001804"
     CDS             9181..10935
                     /gene="ade"
                     /locus_tag="OUE31_001804"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HCU0222811.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            complement(11033..11695)
                     /gene="trmB"
                     /locus_tag="OUE31_001805"
     CDS             complement(11033..11695)
                     /gene="trmB"
                     /locus_tag="OUE31_001805"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HCU0222812.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(11765..12547)
                     /locus_tag="OUE31_001806"
     CDS             complement(11765..12547)
                     /locus_tag="OUE31_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HCU0222813.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            complement(12751..13962)
                     /locus_tag="OUE31_001807"
     CDS             complement(12751..13962)
                     /locus_tag="OUE31_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222814.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            complement(13955..14692)
                     /locus_tag="OUE31_001808"
     CDS             complement(13955..14692)
                     /locus_tag="OUE31_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222815.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            14830..15264
                     /locus_tag="OUE31_001809"
     CDS             14830..15264
                     /locus_tag="OUE31_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HCU0222816.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            15257..15601
                     /locus_tag="OUE31_001810"
     CDS             15257..15601
                     /locus_tag="OUE31_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCU0222817.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            15781..16791
                     /locus_tag="OUE31_001811"
     CDS             15781..16791
                     /locus_tag="OUE31_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCU0222818.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(16860..17804)
                     /locus_tag="OUE31_001812"
     CDS             complement(16860..17804)
                     /locus_tag="OUE31_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCU0222819.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(17788..20508)
                     /locus_tag="OUE31_001813"
     CDS             complement(17788..20508)
                     /locus_tag="OUE31_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCU0222820.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            complement(20505..21725)
                     /locus_tag="OUE31_001814"
     CDS             complement(20505..21725)
                     /locus_tag="OUE31_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HCU0222821.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            complement(22006..22851)
                     /locus_tag="OUE31_001815"
     CDS             complement(22006..22851)
                     /locus_tag="OUE31_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCU0222822.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
BASE COUNT         7055 a         4643 c         3922 g         7330 t
ORIGIN      
        1 ttaacacgta gacgacctgc caactatcgg caggtttttt tgcacaaaaa accgtgataa
       61 aaacaaaaga cgcggcaagc actcatcggt ctttataatg tttaaaataa agggaaaaca
      121 gtcaatgagt tcaagtaaaa taaaaaaaag tgaacaccag ggcgattagt cgccctggtg
      181 tggtttaaaa cgacctaagc atgccaaagc ttattggttc gtcaatgtgg aagtttccga
      241 tgaatctgat acgaaaaaat atgaagtatc gatggcggat accgatttta tcgccaaact
      301 aaaattttat ttcgggttcg ggtaccgcga gaaggcaagt gctacattcg gtaaatcatt
      361 caagaattga tgaaaggcta ccgcttgcca ttgcaaccac aacgatactc ctgaacgcga
      421 tgttggtgag atttccaaag agaagagctg tttaatgcaa cggtattaag caaatggcaa
      481 aaggaagtca tgtagacaaa gttttttatc aaacaccata tgatttcgcc tgaacgctgg
      541 tttagctcag aatacaatga tgtggtccac gagacattac cctcagtcag ataaaaaaag
      601 ctctctgaca gaattacaca tcgataaata ttaagtaaat gtcagcgcta gttgaacttt
      661 ctgacacttt caggtacact ggaaaagaca actacacgaa ggagggaaaa tactatgatg
      721 cgcatgacta aaataacaag taatgaaaat taccaacgat accatatcgc atttagccat
      781 gcaattggtt ttacagttgc tgttgacggg acaagtttgt ccaaaacagt tgaattcacg
      841 taaaatcaat ggccatctca aggtattttt ctcatgataa tctgagttta aataacacag
      901 gccatggata accatggcct ttttgagtgg tctcaaggag agagatcatg atcatacaag
      961 caatttctat taaaaaaaca atcggcggga atccattatt tgaggattta tcctgtcaaa
     1021 ttgaagctgg tgaaaaaatt gccttagtcg gtatcaacgg aactggcaaa tcaacctttt
     1081 tacaaatctt gaccggcaga gaaggtgtcg acagcggtgt tatcagtcgc aaaaaaggct
     1141 taaagatcgg gacggtcgaa caagaactta cagtttccga agcgaccgtc aaccactact
     1201 tgctccattc tgccgctgag atacaggacc tcaaacagca aatgagtcgc tacgaagcat
     1261 tgatgacaga accagataca aacttagaga agtgtctggc ccgttacggt gagctgcagc
     1321 atcgctttga agaactaggc ggttacgtat tagaagaccg gattgcagcg atcttgcaag
     1381 gcttagggat tccacaccgt caggaagcac ggttaacaga acttagcgga ggcgaacgag
     1441 ttaaagtcgc tttagccaaa attttagcag ccgatgccga tttactttta ctcgatgaac
     1501 cgaccaatca tttagatctt aacagtattc gctggttgga aaactattta cagaatacaa
     1561 aaaaatcggt tctggtcgtt tctcatgatc ggcaatttct cgatcaagtc accacaaaaa
     1621 catgggaact ggaagaaggt gcattgattg agtatcccgg aaactacagc cgttttcgag
     1681 tcttgaaaga agctcgcttg gctgagctga caaaaaatta cgaactgcag caaaaagaag
     1741 tccagcggtt gaaagtcatg attcgtcgtt ttcgtcagtg ggcacatgaa ggagacaatg
     1801 agtccttctt caaaaaagcc aaagaactgg aacgccgcct ggcgaaactg acactcgtca
     1861 aaccgccacc tcccccgaaa aatcggctgc aaagcttgtc taatggtgga aaatctggca
     1921 aagaagtttt catcattcaa aacttgcacc agcagtacgc tgatcaagta ctattcaaag
     1981 acagcagttt tgcagtctat cgtggagatc atttagccat catcggcgac aatggtgcag
     2041 gaaaatcaac cttactcaaa ttattactcg gtgaggaaaa gccttacggt ggcaccatca
     2101 aattaggtag tagcttgcaa atcggttatt tgccgcagca gctgcagttt gccgatcccg
     2161 atagccgttt gctggcttac gccatcacat tgactggaaa cgaagaagtc gctcgacggc
     2221 aattagccaa aagtggcttt tatcaaagcg atgtgggtaa acggatcaaa gatttatccg
     2281 gtggtgaaaa aatccgtttg gcgttgctga aactcttttt agaaaaaatc aacgtcctga
     2341 ttttggatga accaaccaat cacctcgaca gctatgctcg agaagaaatt gaagaaatgc
     2401 tgcaagacta tcaaggaacg ctcctagcag tcagccatga ccgctacttt ttgcagcaac
     2461 acttccaaga agcactcgtt attgatcagg agcagatcag ccgccagccg ctcggccaac
     2521 tgattgacta ggacgttttt tcgcaacaaa aaacttgatt ttcatacctg tgctttcacg
     2581 attcaggcaa agtacaggtg gaaaatcaag tttttattat tcgatcaatg aatgtttcgg
     2641 atcggttttc tagctaaaca taaagcgaag aataaagtcg acagcccacg aggctgatct
     2701 aaaaatgttt tttcttttta catatgtaat gtcccttata aagatgaatg aaaataaaat
     2761 attgggattt tcctgaaaat caataaataa aatgccagtc ttttcccttt tgaccacttt
     2821 tccaagcaaa attccctaag aagatcctgt aaaaaagaag ggaaattgaa gttaaattac
     2881 cattttgcgg tcttctccgc aaaaaaaaca catgcaagaa ttccctcttg catgcgtttc
     2941 atcttttatc ctaacgaatg ctttggctta gccgcgcaga cgctccacat cacgggcaat
     3001 cattagttcc tcatctgttg ggatcactaa tactcttact tttgattctt ttgtagagat
     3061 atctacttct tcaccacgca attcattcaa cgctggatcg atttcacaac caaaccaaga
     3121 catacctttg atgatttcac tacgtacatg tccgtcattc tcgccgatac cagcagtaaa
     3181 gacaattgca tcaacaccat tcatcgttgt cacataaccg ccgatgtatt ttcggatgcg
     3241 gtccacgaaa atgtcataag ctaaacgaat atgttctttt tcatagttct tttcaagatc
     3301 acgcatatca ctagacaatc ctgttaggcc tagcagacca gatttcttgt tcaaaacatt
     3361 gatcatttca tcaatatcaa tctctaattt ttccattaaa tatgggagaa cagctggatc
     3421 gatatcacct gaacgtgtac ccattgtcac cccagctaat ggtgtgaatc ccatagaagt
     3481 atccatggat ttacctccat cgactgctgt gatcgataca ccatttccta agtggcaagt
     3541 gatgattttt agttcttcga tcggtttgtt caataatttt gccgcacgtt ccgacacata
     3601 acgatgactt gtgccatgga agccatattt tcttactttg aaatcttcat aataagacac
     3661 cggtaagcta tataaataat tttgctttgg cattgttgag tggaaagatg tatcgaatac
     3721 agccacactc aaaatgtcag gtaaaatctt tttaaacgct ttgatcccca ttaagtttgc
     3781 aggattatgc aaaggagcaa attctgctaa ttcagcaatg cggtccatta ctttctcatc
     3841 gatcactact gaatccccat aagtttctcc tccgtgaaca acacggtgcc ctactccggt
     3901 gatttcatca taagagctta aaatttgcag ttcaatcaac tgatctaaca gcatttttac
     3961 tgctacttcg tggttttcga tatccatgat ttgttcgaat ttttgattat cgccgtactt
     4021 gatggtaaaa atagaatctt gtaaaccgat acgttcgacg atccctttcg caactacggt
     4081 ttcttctggc atttgatata attgccattt caaacttgaa ctcccagcat tgattgcaat
     4141 tgttttagac atatgactct ccttctcgtt gaatgattac agagcagatg atttccagtt
     4201 tttaaactcg ttgaaaaatt ccgtcacctt ctctggttct tttaatgaag caagtttcac
     4261 aagcaagact tcttttactt gttgtgcttg tggtcctttt ttctgtaaga tcaaaatact
     4321 tttttgcgat tgtttattac ggaacaattc atctggcaat tgaatcattc cttgaagata
     4381 accttcttct ttaaaccatt ttttgatttc ttcactttga tccgtttcta aaaatccact
     4441 cggcatcaaa aacaaaccaa aaccatccgg cttcacatat ttcattgatt gctctagcaa
     4501 taaatgatgt gcataactat ggccttcttc ggtacttgtt aaaaactctt ttgctttttc
     4561 gtcattcgga taataaccga ttggcaaatc gctgattgca aaatcgacag gatctattaa
     4621 taattcctgc aacccgtctt gatgaaagta ttgaacattt gcttgtgtca aatcacttgt
     4681 agaagctgcg acagccaaca atgtatcatc aatatccaca ccaattcctt ctgtttggta
     4741 ccccgcattc gataggttta aaagaactgt taataacaag ttgcccattc ctgccgcaat
     4801 atccagaatc ttaaccggtg cttttttatt tgtgtatagt tgttcaataa gaaaaacaaa
     4861 taaaaaaccg atactatcag gagtgagttg atggttcgcc tgcaaatgtt ctgtctggct
     4921 gcccttcaat aaaagtaatt gagacagtct gcgccattct tctggctcga aagaaagttt
     4981 cttcaactct tcataaagag ctgtgatccg ttgcgttgtc tcttttgtcg gcactccatc
     5041 caccacacgt acttgataat catctattaa attttctgca ttttcgacat aggcttctaa
     5101 aaaggaagtt cccaatgcat tctgtaaaag ctgaatagct tccaggtttt gattaaaccc
     5161 ttgttccatt ttttctggta acatggtgca cctcatttct agatatatta taacaatttt
     5221 ttcacctgtt taattctatc gaacaattga caaaatttca atcgttttca ctgtttttta
     5281 tttgtgaaac ggcaaacatt tttttattaa aaacagtgtt ataacagaaa agagggcgtt
     5341 ttcacgaaca ttccatcatt ctgtactagt atctgtatca ttttttactt cttctgtgaa
     5401 ccgaaagata aacggtgaga cttccacctc taagaatagg gactgttgta cccactgata
     5461 tgttacagat ccagttgtgt agtaaaaaac tccttccgaa ctttcggcaa gcgtagactg
     5521 ttccgataaa gccatctgct tcattatttt tgctatataa taatttttga ttcgtatatt
     5581 aagatccatt gacaaacggt agctttctaa tgctgccatc aataaaaacg tacataaaag
     5641 aaataaaagc aagacagaaa ataaaataga gcccttataa cattttctac tgatcgtttt
     5701 ttgtccatat ggcatatcca tcttctccat tttcaaagtg tacataaaaa gaaattgtgt
     5761 gttctttttc caataattga agctcagtga tacttgttaa cataggttga tgtccgccgg
     5821 aagttcttct tttacgtatc attgcctgat atctttcgat gatatactgt ttatcctcga
     5881 tcgtgtagtg cagttgctga tttttcacag agacattgtg actgctcttg agttcttctt
     5941 ctaattgtgc taaaaatatt agccactctt tttgatcttt acgctgcaaa aattcactta
     6001 cttggatggt ttgctgaatc aaaagattga atgtgagcaa tagactgctc aatatcatca
     6061 gtccaattag acattcaatc agcgtaaatg ctggaattac ttgttttttc aatactgatc
     6121 gcttctttct ccatattgac aaacactttt tcgattactc cattattatc gacaatttgg
     6181 atatcgtatg ggatcatttc ttcccttcgc tctggtcttt tgtgatacat ccgctgcgtc
     6241 ttgatatctt cataaatcat tcgaataaat agcagttcct ccccactttt cttttctgcc
     6301 tgaagcaaaa acagctggcc aaagctcact aagtagacac agacagaagc gatcataagc
     6361 gctgtaaggg actccaacaa aacaaatcct gttttattca attctttttg tatagcgacc
     6421 actccctatc tggaattgat acgtaatcgt ccgctctttt tcttcccaat aaaattgata
     6481 agcttttagt gaactttcat tcccggttct agcagcaaaa gtaatagaag catggcgttt
     6541 caaggtaatc tcatcaggaa tatctaatac ttcccaattt attttatctg gattcggaac
     6601 atgaaaaatg atttgattct cttcactatt ccaataaaag cctgtttgga tctgattcac
     6661 aatagcgatt ttttgcgtag aatagattcg tttttcaaat tggccgaaaa attgatagac
     6721 tgccaattca ttcttccatg cagaaaatgc gagaactgga aaagaaagga tcgttgtaag
     6781 taataaaatc agtaagagtg attcaaacaa cgtatatcct gatgctaaaa ccttaccttc
     6841 aaggccgctg atagatttct gcatgttctc gtttgatata gccttcattc aacaattcct
     6901 ccacagtagg aactcttcca ttattttgaa gcgcatagag ctctttttgt gtgtctacca
     6961 actggatgat cgcttcacga ctttcttggt ctacatgatt cctataacgc gacaaattag
     7021 ggacgaacaa caacactaat acactgatga tcagtaagac gattagcatt tcgatcaatg
     7081 taaaaccgct ataataagat atttttctct ttttcatggc aaaacctcct ctatgcttcc
     7141 gtaaacaggt aataaaacag cggcataaac taataaaatc aaagccgcta cgcccaaaaa
     7201 aatgattggc tgaataaaat gcatccagtg atgaagacgt ttgaaaagct gttttcttgt
     7261 ccattcgctg taaaaaatca gttctttacc taaacttccc tttgcctctc cctgtaaaac
     7321 aattttactg aattcttctg atagaaaacg ataattctgg aactgctcag ccaatgacat
     7381 acctgcctcc aatccttgaa tcaacttaga ggcaagatgc tgaatcagac tttcttgttt
     7441 cgtttccttt aagcagacta tgatttgcct taattcgaaa ccttcatgaa aaagctttcc
     7501 aatctctagt gacaaataag ccgattgata caaggaatat atcggtccaa tcaataattg
     7561 tctgcttatc cattcactct gatcaacagg agacaacttc atcagacgat accttactag
     7621 taaagccaat agagtaaccg ctaggatgaa tagtagaaca taccaatgaa agacttgtat
     7681 cagctgaata ccccaatgct cttgcatgac cattcctgaa ccaataagct gaggcaaaac
     7741 gaacaaccgc atactaaaca agatacctag caaaaaggtg agcaatagca tcggatatgc
     7801 aagcagcttt ttcaaatcat tgcgaaatcc ttcaacaagc cgaaactgtt tggcaatttc
     7861 caacaaagtt gtcggcagat tcccatgacg ttcagctaac tcgatctgta ccagttgctc
     7921 tgctccatat cctatttgcg aaagtacctc actaaacgct tgcccttcct ttagctgatg
     7981 ttggatattt gccaaaataa caggtggaaa cgaacggatc gtgagtaata aataaaggga
     8041 ttcttgcaga ctaaaaccag ataaaagcag ttctcccatg gtttgtgcaa actggttttg
     8101 ctggcttctt gttaatcctt tagaatagtt ctgactgcca aatattttcc tgagcttctt
     8161 cataactttc ctcccatgat ttttttactg attcttcctc cataaattga taactccata
     8221 aaacagaagg atggtgattg gcatcttcca aaagttcttg ataaatgaca ccagctaaac
     8281 attcagatag ctcttctttt ttctttgtca gttcatggat tctgaccaat gtaccttcaa
     8341 gattgcgtgc atgtacggtt gcaaaaaccc ggtgccctgt tagtgctgct cttaccgcag
     8401 catgtgcagt tgattcatct cttatctcgc caatgattag caagtctgga cgatgccgta
     8461 atgcgagtct caaaagtgta tcataagtct gtgctatttt cggattgatc tgtagctgca
     8521 gaaaaaacgg ttcttctatc tctacaggat cttcgatagt aatcacttgc aatttttctt
     8581 ccaaagccaa ccgatacatt agagaagtct tgcctgatcc gactggtccg ctgaaaaggt
     8641 ataatccacg tctgacggtt ttctgtaaaa tagttgcaaa atctcgagaa ctaaagcaac
     8701 gatggggtgt ttcaaaagta ccgtataata gccgaatcac taaactctct cgttgaaggt
     8761 aatctcctac agaagacaac cgcagacgaa cttcctgttt ttctaaagaa taagtaaatg
     8821 cacctaactg agcttttctt ttttctccga tatccatctg tcccaaatac ttaaatcttg
     8881 agatcagttg ctgtccatct gccgaagaga ctttcttcca gaatgttcgt ttttttccat
     8941 agcgaaaata gatgtaaaat acttctgaag ctggcaatat atatacgtct tgggcatgtt
     9001 tggcaaaact ttcacttatc atttgatccg ataatcgttt tatttccatt attctcccct
     9061 ccacaaaaaa catacgtctt tttgatcttt ttgtttcaaa taaaatgaat ttacaaaaaa
     9121 atattggcaa aaaccgaatt tatgttatac ttataaaaat ttatcttggg aggcactcca
     9181 ttggaaacaa cattaaggaa atatatcgaa gtagcaagta aaaaaaagcc tgctgaccta
     9241 gtgatcaagc atgctaagat cgtcaacgtc tttacgaaag aaatcatgga aaaagatgta
     9301 gcaatctgcg aaggaatgat cgtaggaatc ggtgaatacg aaggaaaaag cgtacataat
     9361 gctaatgggc aatatctagt gccaggattc atcgatggcc atgtgcatat cgaaagctca
     9421 cttttatcac caagcgaatt ttcaaaagta tccttgcttc atggagttac tactgtagtg
     9481 acagatcccc atgaaatagg aaacattgct gggagtacag gtcttgagtt tatgatagaa
     9541 gatgcaagac aaacactcat gaatatcttt tttatgctac cttcttgtgt acctgtaacc
     9601 ccttttgaga ccaatggtgc aaatttaaat gcaaaaaaat tagccccttt tttacaaaaa
     9661 cccgaagttt taggcttagc tgaagtcatg aactatcaag cagtagcaaa taatgaaaca
     9721 gacatcctag aaaagatcca attgatgcac cagcataaga aaaaaattga cgggcatgca
     9781 gctggtatcg gcatggaaga gttaaatgtt tatcctgcag caggtattcg gacggatcat
     9841 gaagctacaa ctgcaaaaga agctaaagaa cgtttggatc ttggtatgta tttaatggtt
     9901 cgagaaggga ccgttgcaaa agatctggca tcgctactac cggcgatcac acctgaaaat
     9961 tcaagaagat gcttctttgt caccgatgat aaactgatca atgatttagt aaaagaagga
    10021 tcaatcgatc atatcgtccg tcaagctatt gcacttggaa tcgatccatt acaagccatt
    10081 cagatggcaa cattgaatgc agcagaatgt tttgatttga aaacactagg tgcgattgcc
    10141 cctgggtatc aagctgattt cttcttaaca gacgatctta ccaagctgcc aattcatgaa
    10201 gttttctata agggaacatt agttgttcaa tctgggcaac tccaagacca tttatttgct
    10261 gatcattcaa attcatatac gtgttgtctg ccaaaactaa acgctcaacc attaaatcca
    10321 cattcgttag agctgcttct ttcttcttca caagcccatg tgatcgaaat tatcccgaat
    10381 agtctagtga ctaaagattt ggtagaaaaa gtggaccgac aaggcgaacg attcattcct
    10441 tcaatcgaaa aagaccaatt aaagattgcg gtgatcgagc gtcaccatca aacgggaaac
    10501 attggattag gcatagtgaa aggatttcag ctgaaacaag gagcgatagc gacaacgatt
    10561 gcccatgact cgcataatct agttgtcgtt gggacaaacg acgaggatat gctgtatgct
    10621 gctaatcttt tgattcaaaa aggtggcggg atgaccgttg tcaacaaaca gcaggaaata
    10681 gcttgtgttt ctcttcctat aggcggaatc atgacacagg aacctttttc gatcgtctat
    10741 gaacagttga atgaattaat aactaaagca catcaactag gagcagctaa aacctttgat
    10801 ccttttttga cactttcttt cttaacatta tctgtcatac ccgaattgaa gatcaccgac
    10861 aaaggattat tttcattttc tcgcttccaa ttgattccac cttgtggaaa aaccgatgaa
    10921 ataaatacat tttaaatcaa ataaatccca gaaaatacat tacatctgta atgttcattt
    10981 tctgggattt atttatggat attaatgttt ttatgaaagc agaaagttag tttcacagac
    11041 ttttcttttt ggtcttatct tgaaattgag cttctactcg ataaatacgt tgaccttttg
    11101 aagaaaattt ttcttcatac tccgtcataa tattgccttc aaattgactt tgatgtaaat
    11161 ctaaccatac ctgtttgagg atcatgccat attgagaaaa acttgccaga gaatactcaa
    11221 acaatccttg attatctgtt ttgaaatgga tttctccatt tggacgaaga atctgttcat
    11281 ctacagcaag aaaagtctta tatgtcaatc gccgtttttc atgacgtttt tttggccatg
    11341 gatcggaaaa attcagatag atttgatcta cttcgctgtc agcgaaatac tctgtcaacg
    11401 ctgatccatc cacatgtaga agtttcaggt taggaagcgg ttgttcgatc aacttgtcta
    11461 gtgcaatcga aacaacactg acctgcattt ctactccaat ataattgatt tcaggatggg
    11521 cttttgccat tccagtgatg aactggcctt tccccatacc aatctcaatg tggattggat
    11581 gatcgttttc aaacaattca ttccattttc ccttccacaa tgttggatca ctaattacaa
    11641 aattcgggtg agccgctaac atttccgctg ctcccggacg atttcggaca cgcattattt
    11701 atctccattc ctttcctcta attaaaaagg tctggccaaa tctccgcaga gtttgggcca
    11761 aacctcagcc actgaaaatt cgttttaatt gtaaaatttc ttcgttcatc cgtcgatgat
    11821 cttcacgttt gcaatatctg gtgatttctt ggagcaaatt catggccgca taccaatgaa
    11881 atttttcaag catttcgtca gtcgggcgta tgccataact gatcagccac tgattccagc
    11941 tagacagtgg cacataattt cctaaaatcg ttgcaatatc caccgcaggg tctgcaaaca
    12001 tgattgaatc ccaatcgact agatataaat aatttttaca tactaaccaa ttacgatggt
    12061 ttacatctcc gtgtactact gataagtttt ccttatctat tgacgggatc tgctcacgaa
    12121 gaaaacgatg gacaatttgc agaaattgat ttttctggag ttcttccggt aattcttttt
    12181 catatttttg cagcatcttc tccggcgtca tgacacgacc accgatacgg gtcagcatgg
    12241 ttttaagaga atttgaatga tgtaaatggt acaaaacatc aatcacgtcg tttctttgac
    12301 caatctcatt aggagtcagc aagcgacctt ccagccactc ttgtgctgtc aaagtatcgc
    12361 cattccccgt tcgttttgtc caaacaagtt ttggtgtaat tccttccctt gaaagagcag
    12421 ccaacatcgg agtcgtgttt cgtttaataa agactttgtc ctcatcacgc atgcctatgt
    12481 atgtttttcc tgtgtcgcct ttgatgggac gtaaccgcca ctcttggtct aactgaaact
    12541 ccatcatgca ttctcccgtc ctcttactct ttgttttgca gtacttatta ttctagtcgc
    12601 ctgaacacta cacgtcaagc acatatacgt tctttttcat ttaattgcca ttcaaaaaac
    12661 cagcttttct caaaaaaaat agaacgaaca gcattcttac tgtcaacgct ctatttttca
    12721 ttctcatttt taccctacac agctttgttt tcagtctgac atcttcttca aacgagttgg
    12781 tacatatagt ttaacaaaga gcatagtaac aatcaaataa gccgctagcg gaacccatcg
    12841 ctgctgccca tctaatacga ctgcagcaat caaaccaaaa ataaccgacg cgataattaa
    12901 tacccatgtg agtagatact gaatcgcctg cttcttctga ttcttatgga ttggataaag
    12961 ctgaacgaga accatatagc ggaactggtt cgctaaaggt aacagttgga aaccgatcaa
    13021 atataaaaat aagaaaccga taatcagact aaaataaaag tcgactactc cggcaatcaa
    13081 taacccacct ataattacta atcggaaata aagaccacta aaatcagaac ctcttgccaa
    13141 tcttcttgca aacaagtaaa gataagtgtt ttttgattct cttttaatat gagtcaatat
    13201 aggatccaaa tagcgtcttc ttttgatctt tgccgtaatt tcaggaacat ctgtgaataa
    13261 attgataaat tgatagatct gatgcaacct atgttcttct acatgcacca ttttctccca
    13321 atccaatcct ttttcttgtt gcttccacaa aaaccagtaa tatagacttg cctgtactaa
    13381 tgcacctgct attcctgccc atattagcca ataaaatgat agaaacaaaa agatcagaga
    13441 agaaaaaaac cagcctaatt tccaataacg aataacttgt tgatctagtc gaaacaattc
    13501 tgctctcttg atttgcagat gactgaattt caaactccat aatatgatca gatagacgaa
    13561 aaacatcgaa aaggattgct ccgtactaac caccactaat ggcatggcca atccgcatgc
    13621 caatatcaaa aagatcaacg gaaaaatgca agaatagcga aaagctcgtt ccaaataggt
    13681 ttgcatttct ttttctttag gaagtaaaaa aacaatatct gctgcctctg caaaagtagc
    13741 catcttaccc acgaataaac agagcatcca aaatacagag attatgagcc ctccaattgc
    13801 aaacggtggc tgcagggttt tcaaccaatt agaataatat aatcccacac cgccaatcaa
    13861 gaaaagacaa actaaaacaa aatgatcgtt caatacataa cgcatatatt tcatcatttt
    13921 cttttgatgt cttgctaaac gtttttgaaa aaaactactc atgtgcctgc tcctttgtta
    13981 aagcaatata gatttcgtcc aaagaagaat ccggcagctg aaattctttt ctcaacatct
    14041 caagagaacc gtctgctcgt atctctccgt tatgtaagac cacaaaacga tcacaatatt
    14101 tttctgcagt agctaaaata tgcgtagaca tcaaaatacc ggctccttct tttttcattt
    14161 ctaccatcaa ttcaagcaat gcattgatag ctagtggatc caagcctaaa aatggttcgt
    14221 cgatgatata taaagaaggc tcgatcaaaa aggcgcataa gatcatcact ttctgtttca
    14281 ttccctttga aaaattagct gggaaccagt caagacgatt agataaccga aaagtctcca
    14341 acaacttttc tgctcttttc attgctatat ccataggtat atcgtaggcc atcgcagtga
    14401 cttcgatatg ttctctcaat gtcaattctt catataaaga aggagtctct ggaatatacc
    14461 caatttgttt gcgatattct tccgtatttt tctttaagga tagatgattg atttctatcg
    14521 ttccttttga agcttccagc agaccgataa tgtgcttgat ggtcgtactt ttccctgctc
    14581 cgttcagtcc aatcaaccct actatctctc caggctgtac atcgaaactg atatctttta
    14641 acacagggag atgtccgtac ccccctgtga catgatcgat aattaaactc attctttttc
    14701 ctccgccatt tatttttatt tattatacca cgaagaaaat gacggtattt tgtttttttc
    14761 cttacaatag ctttaactta tggtaaagtt aagctgaagt atttattctt tatagaaagg
    14821 atgttttata tggaaaactg tattttttgc aaaatcatca atcaagaaat cccaagctat
    14881 aaaatatatg aagacgacaa ggtctatgct tttttagaca tctctcaagc aacgaaagga
    14941 cacacattag ttgtgcctaa acgtcatgta gcagatattt ttgaatatga tcccgaactt
    15001 gcaggagagg ttttttcgcg tgtgcctaag attgctcaag cattggaaaa agcttttcca
    15061 gaaatgaaag gtcttaatat cttgaataac aaccgtgaac tagcctatca atctgttttt
    15121 cattcacata tccatttagt ccctcgctac agcaaagagg atgatttttc tattcacttt
    15181 gtcaatcatc aagatagtta tggatcggaa gaactaaaag ctattcaaga aacaatcgta
    15241 aagcaggtgt cctgcgatga ttaaaaactt tttcaaagga ctgttatttg gagctgctgc
    15301 tggcactgtc ggaggtctgt tattggcgcc caggagcggg aatgaaacaa gaaagaaact
    15361 gatcgaagaa ttggaagaag caacaactct gacaaatgat ttaaataaca gcctgaatca
    15421 ttttaaaagc gcattgatcg aaacaaaaga aacagctgaa tctgtgattc ctgctttcca
    15481 agaagcaatc aaaaaagata tcgaagattt taaattccaa gccgaaccac gtatcacaca
    15541 aatcaatgaa caagtagaaa aactaaaagc tgatctgcca gagtatcctg aacaaatata
    15601 ataatgatta ttttctcaac agatttaact atataagtga gaaaagtttg cgtatttcct
    15661 aggaatgtga tgaaattttg aattttgttt gaaactacca cgacaacgtt tttaaaggaa
    15721 atgggatatg gtatagttaa tatataaaaa taataactaa ttacaggagt gcaaatttta
    15781 atgaaaaaaa aatcaattat tttggcagct actagtgcgt tggctgtttt aactctagca
    15841 gcttgttcag gcgatactaa taaagatatc gcaacgatga aaggcggaac gatcactgta
    15901 tctgatttct atgatgaagc aaaacttgaa tcatcgaacc aatccttagt acaacggatg
    15961 atcatttata aagtattcaa taacaaatat ggcgataaag taaccgataa gcaagtggat
    16021 gcagaatacg acaaacaagc gaaatcatta ggtgatactt ttgaatcaca attagaagct
    16081 gctggatata cgaaagatac ttataaagaa tatattcgta acaatttagc ttttgaagct
    16141 ggcttgaaag ctcacgtaga tattacagat gacgatttga aaactgcttg gaaatctttc
    16201 catccagaag tagaagcaca aatcatcaaa ttatcaagtg aagatgaagc aaaagatgtg
    16261 aaaaaatcag cggatgatgg agatgatttc tctaaattag ccaaagacaa atcaactgat
    16321 acagagacaa aagaagatgg cggtaaagtt aaattcgact caacgacaac aactattcct
    16381 gcagaagtaa aagaagcagc tttcaaattg aaagacggtg agatctccga tgttattact
    16441 acaacaaatc ctacttctta tgcgacagaa tactacgttg tcaaaatggt gaaaaaccaa
    16501 aataaaggca atgacatgga taaatacaaa gatcaactaa aagatatcgc tactgaaact
    16561 aaactaagtg acaatgcatt cacaactaaa gtaatcggtg aagaattaaa agatgcaaat
    16621 gtaaaaatca aagatgatgc ctttgaaaat gtgttgagtg cattcacaac aacttcatca
    16681 agtacgaaag actcaagtga aactacagct tcaacaaaga gttctgacac aaaatcaact
    16741 gattcaacaa aagaatcttc aactgaagaa acaactgatt catcaaaata aaagaaaaca
    16801 aaaaaagcga agacttatgt ctcgcttttt ttgttttgaa tgaaaaaaat aaatttttgc
    16861 tataaatctt ttggtacata gaaacttcgg ttgtccatac cgaaaatccg atcggtgtat
    16921 tttcctggtt ctgtttgacg aatcgaagtc aacatcatct gcatcgaagc atcgatattg
    16981 tcgatttgat gtaatatttc tgcttccatt attcttggac gtacaggtga gccatattct
    17041 aataagccat ggtgtgctaa aaccatatga cgtaatacga gaacatcttc gtcagcttcg
    17101 ctgattttca acgcaagaca ggctttagtt atttcttcgt caatcaatac cagatgaccg
    17161 atcaaatttc ctgcaagcgt atattctgtc gacataggac cggaaagttc aatcaccttt
    17221 cctaaatcat gcaaaatgat accagcatac aacaatgctc gattcagctc aggatattca
    17281 tcggcgattg atttccctaa gtgaagcatt gtcaaagtat gataagctaa tccactggca
    17341 aatgcatgat ggtttctttt tgctgccgga aactcaaaaa attgtttttg atatttatta
    17401 agtagatagc gaacaatacg attccaatgc gcattggtga tctcaaacaa caattgattg
    17461 atttcttctt ccatttcttc tttcttcaaa ggggctcttt ccatgtataa actaggctct
    17521 cctggctcat ctacccttgt taagcgcata tgaagaatct ttacttgagg gtttccttga
    17581 taaacctctc ttttaccgtt tagaaaaacg actgtgccgg ctgtaaattt attgatttcc
    17641 tcctccgaag catcccagta tttaccatcg atagtacctg aagtatcttg gaaagtaaaa
    17701 gcaataaatt tttttccgtt tttagcgatt cttacatctg cacttttgat caggacaaat
    17761 tgttcaaact gctcatcgat tactaaatca cgaatttttt tcattatttg ctccttctaa
    17821 ttgttttacg atttggttca tctcatggta atagcttacc atttctttat cagaagaaaa
    17881 acaaattatt tgatactttt ctccaaattt agctaaaagt tcagctaatt gatactttcg
    17941 ctgatgatca taatgaagcc agccatcatc aatgatgatc gggcatatcg aacggttagc
    18001 ttctaatgag aggtaagcaa atctcatcgc cataatcagc tgatctttcg tacctgtaga
    18061 taactcatag atgggaaatt ctgtatatcc gtctgttaaa gtcagtgtat catttttcag
    18121 taatatcttc tgataatttc cttttgttaa aatacctaaa taatcacctg ctgctcttaa
    18181 caactggggt aattgtcttt cactcatctc tgttgaaaga tcacctaaga atgtcccggc
    18241 gatttcaagt gctccccatt cctccagtaa ttcctgtaat tttgcttttt gccggctagc
    18301 ttgttgataa agttcgtcca atgtgccgtc tctttgcaac tcttctactt gaagttggag
    18361 tcgttgccga ttttcacttg cttctttttc ttcttgctgg agttgggatt gcttttcttt
    18421 cagttggcgc agtcttacag ataatttctc ttttgtcagc tcttcaggaa atagtggagt
    18481 aagcatttcc gataattcat tgtatctttt catctgctgt tcggcttgtt tggctttttg
    18541 taaaaagaca ggtacttccg aaggataaga taagcctgct tgagtcaatt gttcgctgta
    18601 ttcttgtatc catacttttt gtttcttttt caattgattg atttcttgct tcaataaagt
    18661 attttgctga tagcttctgg caaatttcat ctgttccatc tcttgtataa aacgggaaag
    18721 caataccatt ttttctgaaa ttgtcttatc ttgtatcggt aaccattctt taacaaactc
    18781 aaatttttgg tcgatttgtc gtagtttttc ttgtatttcc tgttctcttt tatgtttccg
    18841 ctcaaatacg ccatataatt tctgataatc tatgacttcc tgtccatatt ctttcatgag
    18901 tttgagcgta tccatctttc ctaagtgccg atgatccgca aaacgatata cttcttgctg
    18961 aagaatctgt ttttcttctc cagttctctt ttgtttttct tctgcttcag ctaattgagc
    19021 taaggctaga tcaagttgtc ctagtttttc ttgccacatt ccttttatct cagagaaatc
    19081 atttttagtt ttaatttttg gttgcctttt gtagaagaaa tagccaatca tgcctgcacc
    19141 aattagtaaa aggatcactt tcaagggcat tggtacaaat atacctgcaa tgattattgc
    19201 tccgccagcc atcagcatat acggtttaga tgaagagact ggtgctatct ctgactgatt
    19261 ttgtaataat gctggatagg tctcttccaa gtcattcact tctgcttcaa tcatctcttg
    19321 ctgttcttta gctatttgga gacgcacaga aatctggctt tctagatcag caatccttct
    19381 ttcttcagcc agaagatgct tccattcttc ttcatataaa aattcttccg gtaacggatt
    19441 tttctgccaa tgccaccttt gttccaaaat cttcaattct gaatttgttt ctctagtctc
    19501 aatttgtaat ctttgccatt cttcgtttaa ttgttccgct gtaaattgaa gttgctggag
    19561 atcttttagt tcctgctcct gctctaaata aaaataatat ctggctgact gctgatccat
    19621 cccgctatgc ttttccagtg ttgcttctaa ttcttccaaa cgctcatttg tttgctgata
    19681 ccgtttggag aaagactcca gatctaaaag aagttgctca tcaggaagac ctgtagtgct
    19741 gttttttttg agagattgcc attcttcata taaagaaaaa ttaagttctt gctgtctggc
    19801 taatgaaaat tgtttgttcg cctcttttaa ttgtgccaat aactgctgct gttgcgactc
    19861 gtattcctgt tcttgttgga tcaacttgcc aaaataagct tcctgttctt gtttttgatg
    19921 aattttttct tgcagctctt tccattcatt taatttttga ttgattagta atttttggcc
    19981 ttttttcttg aataattgtt gtgctttctg ataatattct tgccgctttt ggaatacttg
    20041 agaactgccc gtgatgccta aagaaatcag cgcatcatgt agctcttttt ctctcaaatg
    20101 atctagttcc atcaactgct cttgctggaa agtaaatacc tgctggaata actctttcgt
    20161 caaaggtgcg atcagttttt ctagtaactc atcacttccc acttgatccc ccagccacac
    20221 cttcgatttt ccgcgatttt gctgcttgta gcgctcgaca gcaaattcac catatacagg
    20281 atgtttaagc catattttgc cgccataggc tgagccgtct tttggtgtat aatccttttt
    20341 tttacggcct tttgaaggga aaccaaataa tattgcttga ataaattgat aaatcgttga
    20401 ttttcctgct tcgtttcccc catagatcag ctgattgcct gaataaaagt caaaactttt
    20461 ttgacgccat tttccaaaag cagcaatctc gatccttaaa atcttcattc ctgatcctcc
    20521 tcaaataaaa aatcttgatt aagcagctgc ttggcttttt caagtgtttc ttcttgatat
    20581 tccggcagtt cgctcaatat tctagccgct tcttgatgac tatatacttc atttaaaatt
    20641 tgttggaaat cttgaggtgt ctgatagtat tgaaataact gttccatcaa tttagcagaa
    20701 gcagcaagtg gggtcttcgt ataaaaagta ttctctatga gagaaatacg ccaaataaag
    20761 aaatcattta tcctatctga gaattcctct aacaaatagt ctaatagctc tcctgattgt
    20821 atccgttcca aaacatctgt attgagatgg tcataatctt ttaattttat ctcaattaaa
    20881 ctaaatccat cctctacttt tgaaagctgc tgacgaatgt gaacaatgac ctcttttgtc
    20941 gttcttgctt tcctcaatga tatttccttt gtcttccaat agacctctgc tactttaatc
    21001 ggatgtattt ggcaacttcc tttacttaat tcaactagta gaatagatgt agaagcttgt
    21061 tcctttttag tatgaccttg aggcgcacct ggataaacaa ttgtttgctt ttcatttaag
    21121 accgttggca catggatatg ccctaaagcc caataatcgt atcccttttc ttgcatcttt
    21181 gagggttgga aaggagcata gtttcctttt tgagagacgc caggttcccc gtggtacaac
    21241 ccaatatggt aatctgtgag ttctctagaa ggaaattcca tcactttgtc tttttgaatc
    21301 cacggttgac gataactaaa tccactgaga gagacagttt ctccactttt tatcgttatt
    21361 ttttttgtct ctaccgtttc ggatgtaaat aaatggacat ttttaggaaa ggagaaccaa
    21421 taccgctctt tttgatagaa atcatgattt ccgaatatta taaatacagg tatatggttc
    21481 ttttctaacc gtttcatctg ttctgaaaaa tgtttctgta tttttaatga aggacgattt
    21541 tgatgaaaat tatctcctgc aagtaaaaca aaatcaacgt tatttattat tgcctgttca
    21601 atgatatttg ataaaacggt cagattcgtc ttcaatagtt tttcctgtac agttttatca
    21661 agagttgtca gtccttcaaa tgaccgatcc atatgtaaat ctgccgcatg gataaatttc
    21721 accattaaaa atttcctcct ttttttcttt tatcatacca ttttcaatgt tttttttcat
    21781 caataaccga aaatttgttc gtattatgca aagaaattac gataaatggc cgacttcaaa
    21841 aaataagttt attcgaaaaa aagattgtga catgattttt gtcacaatcc taaatatcta
    21901 tgttatattc gcttcgtttg acactgaaga agtactattt gtactggaat ttatgctcca
    21961 tttttccgta tttagaattc tatgttctat actaccttaa ttagtttata tggtaagaat
    22021 tctttcaaat gcttgagata ctccgtcttt atcatttgaa acagtgacat aatcagcttt
    22081 tttcatgatt tcttgatgac tatttcccat tgcaaaacta atatctgcac tttcaaacat
    22141 agataagtca tttaaactat ctccgatcgc gattctcaaa ggtttcttta aattgtagat
    22201 tgattccaaa cgatcaaaca ccacaccttt agatacattt tgaggtacga tttcaatatt
    22261 tacaggtgcc gattcagtaa cagacacatt tagcatcttt ttcaaatggt taaatatatt
    22321 agctttcaat tgacgattag gaataaaaat aaaaaatttg taaatgctga tagcatcctt
    22381 ttctataatt tcctcaatat tattataagg gattgaacaa atagattttt catactcaag
    22441 ctcatagttt agctctttga tagaaaattc actccctacc tcgtgaaaaa tttttttcat
    22501 tttattttta taattctgag attcataact tccgagattt gtatatattt tggttggaaa
    22561 tttcgatagg acagaatcaa ttttttttac atcattttta tcgaaggaag actcaaatat
    22621 ctttttttct ccatcaaatc caacagaacc atttaaccct actgctggta tccttaaacc
    22681 agattttttg agaatattat taatgtcttc tacttctctt ccagaacaaa tgaatggaaa
    22741 acagtcttcc ggtaaatgtt tcattgttct tgcatttttt tgactaatgc tctggtcaga
    22801 attcaaaaga gtaccgtcta aatctatacc aattagtttc atttcatcca tgtctcctat
    22861 acgttgatta taaattcact gcttattgta agtctaaatt tctcacaaaa catatactaa
    22921 ttatacctaa tttaagtaag tacaaacatc
//
LOCUS       DAKCAA010000043        22308 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000043 DAKCAA010000000
VERSION     DAKCAA010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.043"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            11..703
                     /locus_tag="OUE31_001816"
     CDS             11..703
                     /locus_tag="OUE31_001816"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HCU0222823.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            715..1260
                     /locus_tag="OUE31_001817"
     CDS             715..1260
                     /locus_tag="OUE31_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCU0222824.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            1531..4821
                     /locus_tag="OUE31_001818"
     CDS             1531..4821
                     /locus_tag="OUE31_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HCU0222825.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEVPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGPDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKDHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERLTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNQATGEVLENAKDLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     ASYETKEILHTVDYRKPNYSTVYVTPEGSDTGNGSRQNPLSLTQALRYAYAGQTIVLA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWVLR
                     GFDVTNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVVIK
                     NSVAYRNGWVPGVEGEGNGNGFKMGDSSLSGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDFHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTVSKDWIESLNTHSQEGQQPVTRYANGSIHVHGLMQIKPEN
                     RQTEKGRVDGLPLSVGATFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVV
                     YVMKQRKK"
     gene            complement(5239..7146)
                     /locus_tag="OUE31_001819"
     CDS             complement(5239..7146)
                     /locus_tag="OUE31_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HCU0222826.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNEQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIQYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            7276..8151
                     /locus_tag="OUE31_001820"
     CDS             7276..8151
                     /locus_tag="OUE31_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HCU0222827.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            8231..9205
                     /locus_tag="OUE31_001821"
     CDS             8231..9205
                     /locus_tag="OUE31_001821"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCU0222828.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            9384..10529
                     /locus_tag="OUE31_001822"
     CDS             9384..10529
                     /locus_tag="OUE31_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCU0222829.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSSEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            10666..11010
                     /locus_tag="OUE31_001823"
     CDS             10666..11010
                     /locus_tag="OUE31_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HCU0222830.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            11281..12567
                     /gene="efmA"
                     /locus_tag="OUE31_001824"
     CDS             11281..12567
                     /gene="efmA"
                     /locus_tag="OUE31_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HCU0222831.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(12705..13304)
                     /locus_tag="OUE31_001825"
     CDS             complement(12705..13304)
                     /locus_tag="OUE31_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCU0222832.1"
                     /translation="MNYFTSDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELITQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            13708..14829
                     /gene="mnmA"
                     /locus_tag="OUE31_001826"
     CDS             13708..14829
                     /gene="mnmA"
                     /locus_tag="OUE31_001826"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HCU0222833.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGDMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            15075..16496
                     /gene="arcD"
                     /locus_tag="OUE31_001827"
     CDS             15075..16496
                     /gene="arcD"
                     /locus_tag="OUE31_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HCU0222834.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            16510..17628
                     /locus_tag="OUE31_001828"
     CDS             16510..17628
                     /locus_tag="OUE31_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HCU0222835.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SEFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVNPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILER
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(17688..18980)
                     /locus_tag="OUE31_001829"
     CDS             complement(17688..18980)
                     /locus_tag="OUE31_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCU0222836.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMSFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSISSGHSPSHRQ"
     gene            19112..19690
                     /locus_tag="OUE31_001830"
     CDS             19112..19690
                     /locus_tag="OUE31_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCU0222837.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINDFIATLP"
     gene            19819..20196
                     /locus_tag="OUE31_001831"
     CDS             19819..20196
                     /locus_tag="OUE31_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HCU0222838.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEAEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESGKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            20129..22201
                     /locus_tag="OUE31_001832"
     CDS             20129..22201
                     /locus_tag="OUE31_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCU0222839.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLNLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEEQKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERIPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKMLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
BASE COUNT         7251 a         4029 c         4764 g         6264 t
ORIGIN      
        1 aattaaaaag atgaaaatcg gtattatcgg cgcaatggaa gaagaagtaa aaattttgag
       61 agagaaccta agcgaaccat tatcatggga acgcgcaggc gctttattta tttcaggttc
      121 attaggtaac cacgaagtga tcgtcgtacg ttccggtata ggaaaagtct tagcatctat
      181 taccacaagt ctgttgatcc aacaatacgg cgtgaacatg gtgatcaata caggttcagc
      241 tggcggaatc ggtgaaggct tacaagtagg tgacatcgtt atatcagaca aagtagctta
      301 ttttgatgca gatgcaacag gatttggcta caacccagga caattaccag gaatgcctct
      361 atattatgaa gcaagcacat atttgcgcag tgaaatggtt aaagcagcaa aagcaacgaa
      421 tttgaacgca aaagaaggat tgatcgttac aggtgataca tttgtcgact cgccagataa
      481 aatcaaagaa atcttaacga atttccctga agcattagct tgcgaaatgg aaggagccgc
      541 tgttggacaa acagctcgtc agttcaatat cccatttttg atcgtacgtg caatgagcga
      601 cacagcagat cactcggcga cacaaagctt tgacgaattt atcgaagacg caggcaaacg
      661 atcagcagaa atggtgatcg aatttgtcaa acatctcgta taaggaggac taagatgaac
      721 gcattgatct cgattgacta cacatatgat tttgttgcag aggatggaaa gctgactact
      781 gggacagcag gacaagtaat tgaaaaaaag ctgactgctc atacaaagaa gtttattgat
      841 caaaaggatt ttgtcgtttt tgccattgat gcgcatgatc caaaagattc ctttcatccg
      901 gagaaccgct tatttcctcc gcataatgtg ataggaacgg gtggacggga attgtacggc
      961 tctttaaaaa gtttatacca agactatgag caagaggaaa atgtttattg gatagacaaa
     1021 cggcattatt ccgcttttag tggaacagat ctagacatcc gtttgcgaga acgccagatc
     1081 acagatattt atttgaccgg cgtatgtaca gatatctgtg tgttgcatac agcagtcgat
     1141 gcgtataatc taggatacaa actccatatt ttcaaagatt ccgtggcaag tttcgatccc
     1201 gttggacatg aatgggcatt gagacatttt gagtccacac taggcgcaga aattttataa
     1261 aaaaacaaag tgatttgata aaataaaaag cacaaaataa taaaagaaga gcataaaaca
     1321 aacgactttg ttttatgctc ttttttatac gttattttaa aaaaacttat tctttttccg
     1381 ttaataaatc tctttattat caacaactta agttatattt tttcttttta taaaatacac
     1441 ttattataat tttgtttttt attgacagta aaaataaatt aggtaatact ttaagtaaac
     1501 gctttctaat ttgttacggg aggaatacac ttgttaaaaa aacgtataaa atacagtgcg
     1561 ctaatgatga atctccttat gctcagtacc ccggttttaa tttctgtcgt tgaagttgct
     1621 gctaacgaac aacagtctgt gaacgaagaa aatgcacacg tgaacattga agggatgtca
     1681 acaatggagg aagtaccaag aactagtgaa gatatggata cggaagaagg aaatgatcct
     1741 atgatgaaag aatcagaaaa tgaaaagaca aaaaagcaat ctgaagaagc aaatgaagag
     1801 tggaaagggg ttgttttcgg agaaagcaca agtgctagta ggtatgccat tgaaccatta
     1861 gaagacggcg tgcggctctc ttccacgaat aacggcggaa aattccagtc aagcggacca
     1921 gatggaatga cctattatta tcaagcaatc cccaaagaca tcaactttag gatgcgggcg
     1981 acgatcgaaa tagaatcttg gacctatacg aatgcccaag aaggatttgc tttaatggta
     2041 agagacgcag taccaaaaga tcatttgttt gggcaggcat tttattcaaa ttcatttgcc
     2101 atactaggca gtcggatcga atatgtctgg gactcggata gacaagaagt ggtcaacacg
     2161 agcggcagca aatatacgat gcgacttgga ttagggacac gggcaatcac aggaatatca
     2221 tctgaagatc cgcaagctgc gccagctcct gggagtgtct cagtggaaac aacaccttta
     2281 gagacttcag cagggttctt ggaaaaagaa acaggttctt ataatatatt cggaaacggt
     2341 catgggaatc tgtttccggc cacgaactcg attactaaac tggacgtaga gatgaaaaaa
     2401 acgaatactg gtttagaggc atattattac gatcctgaaa caggagaaga aatggcttct
     2461 gacatcatgt atgactggga aaaattatac gcttcagatg aatcggttat ttatgcagga
     2521 tttgctgcag caaggaatat gacgatcaag gtagaaggaa tcgaagttgc ttactcggat
     2581 cctgcgacag atcctcctgg gcaagaaaga cttactcgct tgattgatcc gatttacact
     2641 gtgacctcta gtaatcattc aggaaaccaa gaccatacta tgtcctttag agcaaatgct
     2701 gacggattat taacaatcaa aaatcaagca acaggagagg tacttgagaa cgcaaaagac
     2761 ttggcaatca ctgcaaatcg ggaatttgat tatcagacaa aactgatgga aggaacgaac
     2821 gaatttactt tcagttttac accagataaa aactatccgc cagaagaata cgtagagatg
     2881 gctagttatg aaacaaaaga gattctgcat acagttgact accgtaaacc taactattcg
     2941 acagtttatg taacaccgga agggtcagat acaggaaacg gaagcagaca aaatccgtta
     3001 tctctgacgc aagcattgag atacgcatat gctgggcaga caatcgtcct ggctcctgga
     3061 acttattcct ttgaaagagg attgacgatt ccaaaaggag ttaacgggac aagagaaaac
     3121 ccgattcaat tgattgcaga gaaaaatcca gaaaacaagc gacctgtact tgattttaaa
     3181 ggaactggaa atgggatgac actgtttagt cattactggg ttttacgtgg gtttgacgtt
     3241 acaaatagtg ccgctatgca aaaaggattg cagatttctg gaaaccataa tttgattgaa
     3301 gagatccatg cttatcggaa tggaaataca ggaatccaaa tcagtggtag ctcaaatgat
     3361 cctttcgaag catggccagc gcataactta gtcaagaact gtacatcttt tgaaaatgcc
     3421 gatccaggat ttgaagatgc cgatggattt gcggccaaac tgacaatagg agaagggaat
     3481 gtatttgacg gttgtatcgc ttatcataat gcagatgatg gttgggatct ttttgctaaa
     3541 aatgaaacag gttcaatcgg gaaagtagtc atcaaaaact cagttgctta tcgaaacggt
     3601 tgggtaccgg gagttgaagg agaagggaac ggtaatggat tcaaaatggg tgattcctct
     3661 ttatcgggcc ctcatgaatt gatcaatagt ttgtctttcg aaaatcttgc aaaaggaatc
     3721 gattccaata gcggaacaga tattatcgtc aatagcagta caagttttaa taacggttca
     3781 tataatgtgg ctctttatac ctcttcggca ggaaacacag acttccatgc ttctggtatc
     3841 ttatctttcc gaacagaaaa tcttgagatg agagagcaga tccgcccatt gaatcaaaac
     3901 gaagatcaaa tctatcactc gttgaactac tattggaatg aacgagagaa acaatcagaa
     3961 aatactcttg gacataccgt atcaaaagat tggatcgaat ctctaaatac acattcgcaa
     4021 gaagggcagc agcctgttac tcgctatgcg aatggaagca tccatgtcca tggattgatg
     4081 caaatcaaac cggagaatcg tcaaacagaa aagggaagag tagatggtct tccactatct
     4141 gtaggtgcta cttttgacgg agaaacctca ccgtcttcgg agtatccaga atatgcaatc
     4201 gtacaagaac caaatcagac aaaaccaaat gaacaaaata atccgattat tatacaagaa
     4261 gcaaatggtg tggcggagaa tgcagaagga aatatcattg aactgaagcc ttttacagtt
     4321 tttgtgtcaa ctttcacacc aaatcaagga acgcctgtct ttgaagatat gcgttatttc
     4381 ccagaaaaga tccaaatcgt tgaaacacag tcaagtgctc aattttctaa tcataccgct
     4441 attttttcag caccttcaaa aggagaatat acgctagaag tcacttatcg ttcggaaata
     4501 tttgatgggg aaaaatggtc tgctcataca gaatctgtta cccagcaaaa agcgatcact
     4561 gtgcgagaaa ctgccgatgt gcccccggga aatgacaaac cagaaagaga aaatccagga
     4621 aatgaatcac caaatggaaa accaaatgga aaaccaaatg gaaaaccttc tcatccggat
     4681 aggacagcaa aagaaagtga aaaaaatggc actcaaggac tcccaaaaac gggagaattt
     4741 aataacccgt tgctagcatt agctggagga attttgttaa tcggtgtagt tgtttatgtc
     4801 atgaaacagc gaaaaaaata agtggaattt ctccttttat gatgtaaaac aattgactga
     4861 ggaaagtaaa aatagaagga aatgagacca atagatgtct cacttccttc tatcttttta
     4921 tagatgaggt tctccttgct gcttttgatt ggctgttctt attacttgat gcaggacagc
     4981 tttttcacaa tctctccact aaacggtgtt caatcagctg accctcggta ttagctcaac
     5041 aaacggcaaa atatgaagaa ctatttttcc gtttttttct ctaatactca ggtcaggacg
     5101 ctgatttcac aacctctcga taaacggtgt tcaaaagcca gtttctcagt agtaagtcaa
     5161 atttatgcaa aaatgtggaa agctattttc acaaaatttt tcttactact tgaaactaag
     5221 cggctttttc acaacctctt accagattcg cactcttttt tctggcgcta gatacatagc
     5281 gtcttgttcc gtgataccaa atgtttcata gaattcgtca aggttttttg gttgcacgtt
     5341 tgctcggagt ttagcagggg catggacatc gatttgcagt aaaagttgtt ggtattcttt
     5401 ttttgctttt gtacgccaaa tcgttgccca attgacaaaa aattcctcga tagaaagatc
     5461 tgattccgtt tttgctgctt ccaatgcaca gcttagaccg cctgcatcag caatattttc
     5521 cgaaacggtt aattttccgt ttacttttcc gtcagcaaaa ggcagaccat cgaattcttc
     5581 gatcattgct tgtgctttgt tttgaaattg tgtaagatct tcttctgtcc accagttgtt
     5641 caagttgcca tattcgtcaa ataaagcgcc gttattatca aatgcatggg aaatctcatg
     5701 agcgataaca gctccgattc caccataatt agcagagctt gattgttcta gactgtaaaa
     5761 tggtgcttga aggatcgctg ccggaaagac gatcacattc cgaaatggat gataataagc
     5821 attgaccgtg tcagcactca tttcccattc tgaacgatcc actggtttgt tccatttgct
     5881 gaaacgatct tttaatgtga gtttgctgaa aacaagagta tttgaaagca aagtaccacc
     5941 ctgatctgca ggtactgttt tgaactggtc gaataatgct gggatcttat cggggtagcc
     6001 tacttggata cctaagttat ttaattttat gacggctttt tcttttgttg catccccaag
     6061 ccagtcattt tcttctagac gttttttata aacggcgatc atttttttca ccatttgttc
     6121 tacgtctttt ttagcagctt cgccaaaata tttttttccg tagtaatcgc caactacttg
     6181 atcgaattgt ccagaggcaa ggtaatacgc tgcttttttc tgaggcattg cttcgtctgt
     6241 tccagacaat acgcgagaat agattccgct gacttggcgg aattcttctg atagataacc
     6301 actaagagaa cgtactgttt taatgatcat ccagcttttg aataacggaa aatgagcttc
     6361 tgtcaggatg tcattcaaat gatcgaagta cactggatca gttacgatca ctttatctgg
     6421 agttgtccca atcaaacccg tgacaagttt tttcaagtcc agtttatctg tgtattgaat
     6481 aaatgtatca aaagattgcg gattatacat tttgctgtaa tctgcgtttt cttctgcact
     6541 ttttacatga ggagcaatca atttatcaaa ttgcactgct tgttccgtga ttgcttctgc
     6601 ctgacttttt tctttgccgg caagctctaa taactgaaca gccatatcaa agaaaacgcc
     6661 tattagttgt gcaccgttgg gatggtctga tgcataatac gtcttatctg gaaggaataa
     6721 agaaggcgga taagcaaaga aggcgttcgt ttgcgcattc ttcatatctg catctacatc
     6781 cagattaaat ggcaatggta atgtatccaa cagccattct ggaaattgct cattcaattc
     6841 gtcgaaagac tgcaatgatt caactttttc gattataggt tgaagtggtt gagcatgcaa
     6901 ctcatttctt cggtcataat cgtttgccag ttgataatat gcaaggaaat gtttcatttt
     6961 ttctgaagac actttttctg gatgggcaag cagatcgtct gtttctccca tcaaaagttg
     7021 gtcgatcccg tcaactaaat cttggaaacc gcctgtagct ggtttatctg cagggatttt
     7081 tgctgttttt tgccattctt cattgactgc ttcatagaaa tcttgtttca atcgttcttt
     7141 gttcattcat cgatcgctcc ttttttgttt cgtgtgccca ttatcttaca aaatgaagga
     7201 attaacaaat agaacataaa aaattgaaaa ttcgaacaat caaactgatt tgtttttttc
     7261 aatccttcac ttataatgaa aaaaaggagg cgatcccaac tgaatcaagt agtggataaa
     7321 cctttatatt tcaaagtaga taaaaaaatt aaaaaattag ccagcactca gcagctgcag
     7381 tcaagaaaaa gtaaattgct ttttttagct ctggtttttg aagatcaaag ttatgtgatt
     7441 atcgatcaat caggacatcc ggtagaatat tctccagcaa aatatactta tcaagagggt
     7501 ctttcttgta aaaaatggaa gctgatcaat gaagagccaa tcgagttatc tagatggatc
     7561 aacagaaaag aagatattcc cgttttgatc gaagaaaaaa ggtcaggaaa ggaactcgca
     7621 aattgctggg tgggattgcc agaagaacgt tttttgaggt ataagaaatg ggctaccccc
     7681 tcaggctatc tttgtggtac ttacgcggca gcagttctcc ttgcctatta tcaagactat
     7741 cgtaaggggt ggatgcttcc aaatgagatt cgcaagaaaa atacggctga ttcgttggtt
     7801 ttgacgaagg cattgcgtag ccagatccaa ccactaggac ttcctacgat tccttttcag
     7861 gttagtacag ggatttctag ttttttaaag aagaatggca atcatgagcg tgcacgagca
     7921 actcttctag gttcatggca gcgagctaca aaacgtatac gtgaaggcaa acctgtgatg
     7981 attggtattt tgaaagtact tggcagtaca tatggcaatc attgggtgac agcgtacgct
     8041 tattttgaaa ctgaaacagg agaacgttat tacaaagtac acgacaactg gggcgattat
     8101 cataaagtca ttcctgccag ttggagtaac ggaacagttt cacttcctta agaatttgct
     8161 gaaattaaca gaaaatcttg gaaaaatatg ttaaactatc gaagaataga gaagttttgg
     8221 ggaggactac atgagtaata agtatcagga tgacacgttg aagattttta gtttgaatgg
     8281 caaccgtcca ttagctgaaa aaatcgcgaa agtgttcgga acagaattag gtaaaagcgt
     8341 cgtgaagcaa tttagtgatg gcgagatttc catcaatatc gaagaaagta ttcgagggga
     8401 tcatgtgtat atcgttcaat caacgaatgc acctgtcaat gactactata tggaactact
     8461 gatcatgatc gatgcaatga agcgagcaag tgcgaaaacg atcaatgtcg tattgcctta
     8521 ctatgggtat gctaggcaag accgcacggc gaaacctcat gaaccgatca ctgcgaaatt
     8581 gatcgctaac ttgatcgaag aagcaggggc aactcgagta ctgactttag atctgcacac
     8641 ggttcaagta caaggattct ttgatattcc tgtagataat ttatttacga tgccgttgtt
     8701 tgctcattat taccgtcaat taggtctgac gggagatgac atcgtagttg tttcgccaaa
     8761 aaacagcggt gttcagcgtg cacgtagtct ttcagaatat ttgaacagca cattagccat
     8821 cgtagatcat gcagatgatg cttcaactga gggtggttat gtgatcggtg atgttcaagg
     8881 aaagacatgt atcatggtag atgatatctt gaacacagga gcaacgcttg cacgagcagc
     8941 aaatgtatta aaagaaaacg gcgcaaaaga agtatatgcc tgtgcgtcac atggattatt
     9001 gtccgatcat gcgaaaagta ttttagacaa tgcaccaatc aaagatattt gtatcactga
     9061 ttctgttttc acagaagaaa atcgtcatcc agaaaactta acaatcgtta catgttcaga
     9121 attaatggga gaagcggtca aacgcatcca tgaaaataca ccgatgagtc cgttattccg
     9181 tctggaagaa aaagaattcg aataaacaaa aaaagaggga aagaagttgt gacacaagtg
     9241 agcagcttca aggagctgcg acaagacttt tgtcacagct ccttttttct atgcccatga
     9301 aacgtcctct agacaaaaat gagctcttct ttggtttgtt cgctatttta tgctagaatg
     9361 tgcctagcaa taatttggaa gggatgaatg aagtgaaaac tatttatctg gatcatgcgg
     9421 caactacccc catgcatcca caagtaattg aagcgatgac ggcaatcatg caagacacgt
     9481 ttggaaatcc ttcaagcata catggatttg gtcgccacgc gcatgaaaaa ttggaaacag
     9541 caagacaaat cattgcagac agtctgcaag caaaacctca cgagatcatc tttaatagtg
     9601 gtggaacaga aggggataat acagctatct tagaaacagc gttctcgcgt caaaaagaag
     9661 gcagacatct aatcactaca gctatcgaac atcctgctgt tcttaatacc atgaaatatt
     9721 tagagacaaa ggggtttgac gttacatatc tgcctgtaga tgaaaaaggg aatctgtcga
     9781 tcgaagaggt caaaaaagcg ttacgagaag atacgatctt ggtctctgtg atgtacggga
     9841 acaatgaaat cggaaatttg atgccaatca aagaaatcgg tgaactttta gcggatcacc
     9901 cagcttattt ccatacagat gcggtacaag cgtacggaaa ccaaacgatc catccagaag
     9961 aattaggaat cgatttatta agtatctctg ctcataaaat caatgggcca aaaggcgtcg
    10021 gtttcttata taaacgagac ggagtaaata tccctgcatt gcttttaggc ggggagcagg
    10081 aagaaaagcg gcgtgcaggt acagaaaatt tagcagggat ctggggtatg gcaaaagcag
    10141 ttgaactgct gtcatctgaa gaacgtgaag cacgtaacaa caaatataaa ggattccagc
    10201 aattgattct tgatacatta gaagcaaacg aaatccctta tcaagtaaat ggtgatttaa
    10261 cgaataaact ccctcatgtg ttgaatcttc gcttaattgg cgaagcaaat gatttgctac
    10321 tgatgaagct tgatcttaat ggggtcgcta tttctactgg ttcagcttgt acagcaggaa
    10381 atatcgagcc ttcacacgta ttagaagcaa tgtatggaga agatacaccg atactaaaag
    10441 aatccatccg tatcagcttt ggtttgggaa ataccgaaga cgacatccag tatttccttg
    10501 atcaattagt tcgtgctgtc aaaaaataac tagtgaagtc attcttatat gaacagatgt
    10561 ctgagagaac gccttcattt tttagggaac ttaactgaaa aacctagtaa aaatcaggat
    10621 aaacttttat aataaagaga aactaatttt atcgaggtga aaatcatggc atttgaaaca
    10681 acagcaacgg tactgggcgc accaattagc tatcgtttgc atcctgatgc aaaaagatat
    10741 acattgcgcg ataatggatt tacagaaaca aacggaggca attatcaatt gatccgacca
    10801 ttagatgcca cgccgcaaag caaagaagga ttcaaattaa aaatcactgt atcaaaagat
    10861 attcaaacat tgaaaatgtc gatcactaca gcaaatggat tgaaagcagt caatattttc
    10921 aaagatccaa aacagaaaat gagccaagat aaattttatt ttctgatgga tgggatgatt
    10981 agccgtgggt tattcgaaaa agtcgaatga tctgtggata taaaaagaca actagttttg
    11041 aaacggccta ttgttagatg actaactttg taaggacgac gcaaattagt tgtctttttt
    11101 atttttaaat ttaacacatg ttgttatttt taatattttg ctgatttatt gtttctaagt
    11161 aaagaaattt aaattgaaac gattgttatt tagggaaaaa ggtatttttt gaaaaaagaa
    11221 tcccgtataa tgattgttgt gcaaacgcta tacaaaatga aaaagaaaag agggatgttt
    11281 atggaaaatg aacagtcggt cgttttaacg aattggaaga gaaattattt gttcttttta
    11341 tcgggacagt ttttgtcagg aatcactagt atggtcgtcc aatatgcgat catctggtat
    11401 ttgacaagag aaaccggttc ggcgacaatt ttgagttttg ctactttact aggaatgatt
    11461 cccatggttt tactaagccc atttgtagga ccgctagtgg atcgctggga taaaaaagct
    11521 cttttgattg tcacggatat tattgtagcg attttcgcgc ttattttagc agtagtcgga
    11581 acgatttcag aatccttccc gatttggcta gtttttgtgt ctttgtttat gcgttcggtc
    11641 gcacaaacat tccaaatgcc aacgatccag tcgattatgc cgacaatcgt tccatcttct
    11701 cacataacaa ggacgaatgg acagttagga atggtccagt cagcgaattt catcattgcg
    11761 ccagctctag gtgcggcttt gttttcagtc gttcctgtca attaccttat tttattagat
    11821 gtattggggg cagtttttgg tgtcggctta ttgatttttg tgaagatccc aaaagtttct
    11881 cctgaaatat tggaagttcc gcttactatt tttaaagatg caaaatttgg gctgcagcaa
    11941 ttgatggata acaaagggtt atggtacata acgatcaatg gtgcatttgt gatgctgttg
    12001 ttcatgccag caatcagtct gtatccattg atgacgctag attactttgg tggttccgtt
    12061 ggacaggcgg gagcagtgga agtagtctac gcagtcggaa tgctcttagg cggtgcactg
    12121 atcagtttta taggaacatg gaaagaccga atgaaaccta ttattatagc ctacatcatt
    12181 atgggcctga cgatcggtgc aagcggattg gttccaaacg atagtcaagg gttcttgtac
    12241 tttcttatct tgaatgcagg agcaggttgt gcaacgccat atttcaatac actgctgatg
    12301 gcaatgatcc agcagagtta tgaatcgaat gttttaggtc gtgtcttagg gaacttcaac
    12361 tctttgatga acctggcagg tccaattgga ttattatttg caggaccatt agctgatcgt
    12421 ttaggagtag aaaaaatgtt cttgttttct ggaatcggga ttttattatg cggaatcgtt
    12481 ttatttttaa cgtcagctgc tcgaaattat gataaagaat tacagaaaaa attggtaaaa
    12541 gaacaccatg agcaaaaaga cgaatagtat ggaatggagt tgtgacagaa gtcttgttac
    12601 aactccattt ctgatcctaa tgttcctgtg gcaataagcc tactcaaatg aaaaatatga
    12661 gtaattatct ttatttgttt aatacttgat atagggcagt tttttcacga cctatcgtac
    12721 ttcctctttg cttcatagat ttctttgatt tgttgctcag ataacggagt gccaaatggt
    12781 agtttttcct ttaagagttc tctttccggt gcgtctacgc ctacattgac atcgttctcg
    12841 ataggtacgc tgtaatgatg gatatgtcca tgaagattgc ggatagtgtc gttaggcccg
    12901 agcaacatcg gataatgagt caagtaatat tgttgatggt cgaatttaac gatggcacct
    12961 acatcataaa aataaaattt gggacttccg tcagtaagcc taggatcatt tttttctaaa
    13021 taacggaaaa aagcacgact gtcatggttc cctttgatca agtggattgt tccttgcagt
    13081 tgagtgatca gttccaaaat ttctgcattt gctttttcat attgcggatg catagcaagg
    13141 tcgcctagat gataaacatg gtcggtttct tttattactg cattccagct agtgatcaac
    13201 tgttggttca tttcatccac atttgcaaag agccgcggag caaagtcgtt ttttcctaat
    13261 aagcgttcat ggaaaaagtg catatcactg gtaaagtaat tcatgtatct cttgcctccc
    13321 ttttttctta gagtaaacaa aatcacttat ctgagcaact cataacatct aaaaagaaaa
    13381 ggttgtaaat gagacgtgca gctttaagcg ataagaagca attttgaaaa atagtttttc
    13441 acaatttaca aaattattcc ttattgccga aaggctggcc ctttttatga gtatgccaat
    13501 tttttatatc gaatgctcaa aagatgagtg attttttggt tgactatcat gtttgtgtac
    13561 tgaataggtc cagtagaaca gtatttttac gacttgataa ttaagggatg aaattttcag
    13621 aaatatgacg tataatgtaa aatactgaaa agttgcgacc ttcaactcgt agatgtttca
    13681 gaatctaatt gaaatgatgg tgatatcatg acagacaaca gcaaaacacg cgttgtcgta
    13741 gggatgagcg gcggtgtcga ctcatctgta acagcacttt tgttaaagga acaaggatac
    13801 gacgtgatcg gaatattcat gaaaaattgg gatgacacgg acgaaaacgg tgtatgcacg
    13861 gccacggaag attataagga tgtagcgaaa gtagctgctc aaatcgggat tccttattac
    13921 tctgtgaatt ttgaaaaaga atattgggat cgtgtatttg aatatttcct agccgaatac
    13981 cgcgcaggac gtacacctaa cccagacgtg atgtgcaaca aagaaatcaa attcaaagca
    14041 ttcttggatt atgcaatgga tcttggcgcc gattatgtag ctactggaca ttatgcgcaa
    14101 gtcactcgcg atgaaaacgg cgtggtccac atgcttcgtg gagtagacaa taataaagat
    14161 caaacttact tccttagcca attatcacaa gaacagcttt caaaaacgat gttccctcta
    14221 ggcggcatgg aaaaatcaga agtacgggca attgctgaac gcgcaggcct tgcgactgct
    14281 aagaaaaaag attcaacggg aatctgcttt attggtgaaa agaacttcaa acaatttttg
    14341 agcaactatc tgccagcaaa aaaaggagat atggtcactc ttgatggtga agtcaaagga
    14401 caacatgctg gcttgatgta ttatacgatt ggtcaacgtc aaggactagg gatcggtggc
    14461 ggaggagatt cgcaagaacc ctggtttgtt gtaggaaaag atctagcgac aaacacatta
    14521 tatgtggggc aagggttcca tcatcctgca ttgtatgcca caagcttgga tgcaagtgaa
    14581 atccacttta cgacgaatga accaatgcca aaagaattca agtgtacagc gaaattccgt
    14641 tatcgtcagc aagacgttcc tgtgacagtt cgcttattgg atgataatcg tgcagaagtc
    14701 gtattcgacg aacctgtacg tgcaatcact cctggacaag cagttgtatt ttatgatgga
    14761 atggaatgtc tgggtggtgg tttgatcgac cacgcatatc aagaaacaaa agttttacaa
    14821 tacgtttaag cgatattaaa tgaatcaaaa cagctatggc taacaaaaga aacacctttt
    14881 cttttggata gcatagctgt ttttttgcaa taaaattaat ttttattcat tttatacttg
    14941 aaatacttgt gtaaaaagtt cataatatcc aataatatga ataaagttgc tttttgttaa
    15001 gcaagagcag ttgcaaaata gaagggaatc ttttgcaagt gatttgttca attttataag
    15061 tgagggtgat ggaaatggaa aagaaatcga cgggtattag caaatgggga ctggttgctc
    15121 tggttgtcag ttcgtcaatc ggaagcggtg tgtttgggat cacaagtgat ctggctagtt
    15181 ctgcagctcc agggccagcg atcctttcat ggataatcgt tgggattggt attttagctt
    15241 tggtattatc gctgaatcat ttaggagaaa aacgtccaga tctagatggt ggtattttcg
    15301 gttacgcgga agcttcattt ggtaaattag gtggcttcat cagtggttgg ggttactggt
    15361 tgtctgcgtg gctgggaaat gttgcctttg caacgatgct gatgagcgcc atgggagaat
    15421 ttttcccgat attcaaaggt ggacaaaatg ttccttctat tttatttgca agtattttta
    15481 tttggggtct gactttatta gtaaacaatg gagttgaagg agcgagcgtc atcaatacaa
    15541 tcgtgacgat ctgtaaatta gtgccattat tcctattttt aatatttgta tttatcgcat
    15601 ttaaagtgaa tatattcact gctgattttt ggggtaacgt atctgataat ctagtgaatg
    15661 gaacagggca gcaaggaacg atctggttgc agattaaagg ttgtttgatg gttatgatgt
    15721 gggtctttgt agggatcgaa ggcgcaagtg ttttagccaa ccgcgcgaag aaacgttcag
    15781 aagcccagca agcatcgatc attggtctgc tttgtttatt gtttatctat atccttgctt
    15841 cgatcttgcc atacggcgtc ttatctcaag aagagttagc aactatttca caacctgcta
    15901 tggcaaatat tttaaaagga atcgtgggaa attggggagc agcgctgatc aatatcggct
    15961 tgattatttc gatcattggt tcttggttgt cttggacgat gctcccagca gaaacaacga
    16021 tgttgatggc tcgagacggt ctgttgccga aaggttgggg aaaaacgaat aaaaaaaatg
    16081 ccccaactta ttcgttagtt gttactgcaa tcttgactaa tctattctta ttgactttct
    16141 tagttactga ttatgcctat caatttgcct attctttatg tacagcggca attttgattt
    16201 gttatctact tgtcgggatc tatcaagtcc agttttcttt aaaagaagga atcaaaaaac
    16261 aagtagtgat cggtgggatt gctgtagttt ttgaattgat gggcatcatt ttagcaggat
    16321 tttcttatgt ccttttatgt agtattgcct atcttcctgg tttttgcttc tactggatcg
    16381 cttgtcgtga aaccaaacat caaattacgg gaaaagaaaa agtaatgatt gggctgattt
    16441 gtgtggccgc actgctttca atcgggttgc ttgctgtagg ctggatcaag atataagggg
    16501 gaaagaaaca tgaaaatcgc aaatttcggt gtagaagaat ggctaaataa atgggaaaag
    16561 aaagcggtat atgatattgc acaaagctcg atcgaagcat tgacattaga cgaactcgtt
    16621 ggcttagatg ggactagcgt aagtgaattt ttcgaaaaac gcaaaaacga accattggac
    16681 tatggctgga tcgaaggatc agatgttttc aaacaagaag tcgcttctct ttatcaaacc
    16741 gtcaatccgg aaaacatctt acaaacgaat ggagcgactg gtgctaatct tttagctcta
    16801 tacgcgttag tggaagcagg agaccatgtt gtttcgatgc ttcctactta tcagcaatta
    16861 tatgacatcc ccaaatcttt aggtgccgct gttgactttg ttcatttgaa ggaagaagaa
    16921 gattggcagt ttgatttaga acagctagaa gccttagtca aacctgaaac aaaaatcatc
    16981 tgtttgaata gtgcaaacaa tcctacaggc acattgctag atcggaaaac tttagaaaaa
    17041 atcgcagaaa ttgctcgtac agtagatgca tatgtattga tagatgaagt atatgcgcct
    17101 ttaacggata aaggtgaatt cttgtcgatc gtagatgtct atgaaaaagg tatagcaacc
    17161 aattccctat ccaaaaccta ctccattcca ggtattcgta ttggctggac agctactgga
    17221 cctgagttgg cagaagtttt tcgaaagtat cgagactaca cgatgatttg cggcggagtc
    17281 ctgtcagatg atcttgctgt acatgcattg aagaataaag aaaaaatatt ggagcgaaac
    17341 aaaaagatca ttacagagaa ccttgtgatt ttaaaacaat gggtagccaa tgaaccgaaa
    17401 gttgaacttg tcgctcccaa ttacgtctct acttctttca ttaaattagc catcgaagaa
    17461 gatgaccaga cattttgtat caatttatta gaagaaacag gagtactatt agtaccagga
    17521 agtgcctttg atttaccgaa gcatgcccga ctaggttact gttgtaaaaa agaaaccttg
    17581 gaaaagggat tattcctctt atctgagttc ttgaaaaaac aggcctaaac aaaaacactg
    17641 caaggacagt ctgtgacaac tgttcaagca gtgtttttca tttacgctta ttgtctatga
    17701 gaaggagagt gccctgaaga tatggagact cctgaagctt tttcttctgc agtttcttgc
    17761 tgatggattt cttgtgtatt gtgtcgtaca agcaagaagt tgaccaaaac aagaagagaa
    17821 gtcgaaagaa aaacgccacg ataaccaaat gcactggaaa cactggagcc gatcataggc
    17881 cctactacgt taccagttgc ttggaaagat tggttataac tgaagatccg tccagcagct
    17941 tgatgaggcg aatattttgt gatcaatgct tggacagcag ggagcagaca agcatcagag
    18001 ataccaatca aaaaacgtaa ggcagctaat tgccaaacat tcgtgacgaa tgacattggg
    18061 atataaacca gaatcgcaaa acccaaacca atcgcaagta ttctttcact cccgatcttg
    18121 tcacctaagc gaccaaatct tggagcggct atcaaagtgg caatcccagg tatcgaagcg
    18181 atgattccgc tgatcaacgt aacattccca tgtccatgca gcaattggcg aatgtacaga
    18241 ctgatgattg gactaatgga attgttggat gcttggatga tcatcgttgt gacgaacata
    18301 ccgatgacga cgtgtggata tttcaagtct ttgaaaatct gtttggcaga aaccatgttt
    18361 tcttttttca ctgggacaaa tttttcatgg acgaaaaaca gactcaacaa gaagacgaaa
    18421 aataagatga tccctgtaat gaaaaaggta gggcgatagc caaacgctga agcagagatc
    18481 ccgccaagaa gcggtccaag taatgttcct gtaacagaac cagttgctaa ggttccaaga
    18541 acttgaccac ttttttcttt tggcgtccca gttgcgacaa gggcagtggc attactgata
    18601 taaccagaaa aaatcccttg aagcagacgc aatgcgacta attgatacac actagtcacg
    18661 caacccatca aagaaatgac gattgccatt cctaatgaag cacgcaacag catcaatttt
    18721 cttccttttt ggtcggctaa ttttccccac caaggagaga tcagcgtagt caccaagaaa
    18781 gtagatgaaa aagtcaatcc gctccaaaag ttcaattgtg acgtactata attacctaac
    18841 gtatctatgt aaagtgacat aaaaggcatg actaaactaa atccgatacc agccataaat
    18901 gttccaaacc ataagacaaa caagttttgt tcccaagttt ctcttttcct aaataatttt
    18961 tcctttattc ttgcagccaa ttagactcct tctttctgaa aattttcatc tacagatctt
    19021 tattataaac tacaatatgt agtttatcaa tgaaagtctc ttttttctct ttctttttcg
    19081 tggtaaactg aaagagtgaa ggatttattt tatgagagga aacatggaaa tgaaaaaaag
    19141 aaatctgtct caagagaaaa tcatcgactg ctttcgagaa ctagcagaag agatggatgt
    19201 tcagcaaata acctttcagc atttagccaa acgcttggat atcaaggctc cctcgctgta
    19261 taaccatttc aaaaatattc gtgatgtcaa aacagcgcta acagcgaaac ttctgcagga
    19321 acttaatgac cagctgcgtc gggctcttgt aggaaaaagt ggtcaggaag cactgcagat
    19381 ctatgcagaa acttatcgat cctttgcttt ttcaaatcaa gcagtgtatg agttactgat
    19441 cagtgtaccg cataccaatg aagctgtttt attagatgga atccatgaaa cgaatcagat
    19501 cattttgcag atatttgagg cttttcaatt aacgaaagaa gaaaaagttc atcgaagcag
    19561 ggaacttcgt agtatgatcc acggttatct ttccttacgt tttttaggat actttacaaa
    19621 agaaccaaca atcgatccag aagacagcta tttttggatg atcaatgact ttatcgctac
    19681 tttgccttaa acaatcagat tcatttgtaa caattttaag atgttcatta aatgaccctt
    19741 ttataagaga aaattcttgc aactttcttg aaaagtgact aagatgagtc tagaaaagct
    19801 gaaagaagga gcacgagtat gtatcaagta attaccatgt tcggggacaa tgagccttgg
    19861 tggttttttg aagactggga agaagatatt gaagcagaag aaacattcga gtctttcgaa
    19921 gaagcacgac aagcgtacga aaaacaatgg aacgaaatcc atcaaaatta tgaatatatc
    19981 aatgcaaaaa gtaactttct cagcgccttt tggaatgacg gagatgagcg ctggtgtgaa
    20041 gagtgtgacg atgatttaca gcaatacaaa ggacttgcgt tgttgaaaaa tcatcagccc
    20101 atcacagtag aaagcggaaa ggaattttat gaaacaacta attctagcgg aaaaaccaag
    20161 cgttgcgaaa gacctaagca aggtgcttgg tgctaatcaa aagcacaaaa attattatga
    20221 aggacccaag gtgatcgtta cttgggccct tggtcattta ttaggattga aaatgccgga
    20281 agatctgaat aaggaatggc agagctggca aatggacacg ttgccaatga tccctaaaaa
    20341 actaggaatc aaaccacttc ctaaaacagg acatcaatta aaagcaatca agcagctagc
    20401 tcagcgaaaa gatgtctcag aagcagtcat tgcgacagat gccggaagag aaggggaact
    20461 tgttgctcgc tggatcttag agtatgtgca tttcaataaa ccagtgaagc ggttatggat
    20521 ctcttctcaa acagataaag caatcaaaac tggattcaag caactaagac ctgcgaaaga
    20581 atatgatgca ttgtatgaat ctgctcttgc ccgggcaaaa gcggactggc tggtaggatt
    20641 gaatgtgacc agagccttaa ctgtgaagta cgcggataat ttatcagcag gccgtgtgca
    20701 gacaccgaca ctagcattag tgagagacca agaaaagaaa atcgagcagt tccgtccaca
    20761 aacgtatttc acgatcacgt tgcaagctgg aaaagaacaa gccaaaatgc ttcaaaaaaa
    20821 tcaatttgct ttaaaaacac aagaagaagc acaaaaactt gttcaattga tcagtacaag
    20881 caaaggaact gtcacagaag tccaagaaaa attaaaaacg gaatctgcgc cattgcctta
    20941 tgatttaaca gagatccaaa gagaagccaa tcaacgctat ggctattctg caaagaaaac
    21001 attaaatctt gtacaaagtt tgtatgagac ccataagatc gttacttatc cgcgtacaga
    21061 cagcaaatat ctgacaaatg acatgaaaag tacgatgaaa gaacgattgc aagcagtcag
    21121 cgactttgct cctgaggtca agcagtattt gaaaaacgga gccatcgtcc aacagacaaa
    21181 agtattccaa gacagtaaag tgaccgatca ccatgcactt ttgccaactg aaaacagagc
    21241 acgttatgaa aaattaagta atgaagagca aaaaatctat caaatgattg tctctcgttt
    21301 tttaggactg tttgctcaac cccataaagt cagccaaaca aaagttacgg ttgaatttgg
    21361 taaagaacga ttcatttttc ggcaaaatcg tgtcgtccaa gcaggatgga aaggcgaaac
    21421 tgaaactgag acggaaacag tcaaatggga aaaaggaatg agaatcaatc ccgatttcgc
    21481 catcaaaaaa gaactatctg caccgcctaa accattgtca gaagcaagct tgcttggtca
    21541 aatggaaaaa tacagtctgg gaaccccagc tacgcgtgca gagattatcg agaaactaat
    21601 caaatctgaa ctgatggaac gtatccctca aggactgcaa gtatctccta aaggtaagca
    21661 attattagta ttggtaaatc cctctttagt aacaccagat ttgacagaaa gctgggaaaa
    21721 agaccttgaa gctattgctg caggaaagaa acaagcagga accttcttga atggaatcga
    21781 aaaagaaaca aaacgcttgg tgaatgagat caaatcaagc aaacaagaat atcaagattt
    21841 ctcgattacc caaaagaaat gcccagaatg tggggccaat ctgcgcgaga aaaacacacg
    21901 tgacggcaaa atctatgtct gcaccaattc agattgcaac taccgcagaa gaaaagatcc
    21961 aaaagtctct aatcatcgat gcccgcaatg tcaccggaaa atggaaatca tcgaaggtaa
    22021 aaacggtgct tatttccgtt gtaaatacga tggaacgaca gaaaaaatgc ttgataaaaa
    22081 agagcagaag aagaaaatga ccaaacatga agaacgacgc ttgctgaaaa aatatgcaca
    22141 agcagaagaa ccagaagaaa gcccattagc agcagcacta aaagcggcaa tgaagaaata
    22201 ataagatatg aaagaggttg tgacagaagt ggtcagcttc aagaaataag aaggaattta
    22261 cgaaaattgc ttctcaaatt tttgtgaaat ttcggcttat ttccgaag
//
LOCUS       DAKCAA010000044        22155 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000044 DAKCAA010000000
VERSION     DAKCAA010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.044"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(108..353)
                     /locus_tag="OUE31_001833"
     CDS             complement(108..353)
                     /locus_tag="OUE31_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222840.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
     gene            673..1434
                     /locus_tag="OUE31_001834"
     CDS             673..1434
                     /locus_tag="OUE31_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCU0222841.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
     gene            1662..1856
                     /locus_tag="OUE31_001835"
     CDS             1662..1856
                     /locus_tag="OUE31_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222842.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            2125..2424
                     /locus_tag="OUE31_001836"
     CDS             2125..2424
                     /locus_tag="OUE31_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222843.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(2521..2955)
                     /locus_tag="OUE31_001837"
     CDS             complement(2521..2955)
                     /locus_tag="OUE31_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0222844.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(3187..3897)
                     /locus_tag="OUE31_001838"
     CDS             complement(3187..3897)
                     /locus_tag="OUE31_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCU0222845.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(3887..4747)
                     /locus_tag="OUE31_001839"
     CDS             complement(3887..4747)
                     /locus_tag="OUE31_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HCU0222846.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(4752..5390)
                     /locus_tag="OUE31_001840"
     CDS             complement(4752..5390)
                     /locus_tag="OUE31_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HCU0222847.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(5405..5704)
                     /locus_tag="OUE31_001841"
     CDS             complement(5405..5704)
                     /locus_tag="OUE31_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0222848.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            complement(5747..7231)
                     /locus_tag="OUE31_001842"
     CDS             complement(5747..7231)
                     /locus_tag="OUE31_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCU0222849.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            complement(7251..7712)
                     /locus_tag="OUE31_001843"
     CDS             complement(7251..7712)
                     /locus_tag="OUE31_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0222850.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(7730..8797)
                     /gene="ulaG"
                     /locus_tag="OUE31_001844"
     CDS             complement(7730..8797)
                     /gene="ulaG"
                     /locus_tag="OUE31_001844"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HCU0222851.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            9015..9785
                     /locus_tag="OUE31_001845"
     CDS             9015..9785
                     /locus_tag="OUE31_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCU0222852.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(10058..10885)
                     /locus_tag="OUE31_001846"
     CDS             complement(10058..10885)
                     /locus_tag="OUE31_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0222853.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            11452..12687
                     /locus_tag="OUE31_001847"
     CDS             11452..12687
                     /locus_tag="OUE31_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCU0222854.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(13686..13946)
                     /locus_tag="OUE31_001848"
     CDS             complement(13686..13946)
                     /locus_tag="OUE31_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCU0222855.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(13973..15274)
                     /locus_tag="OUE31_001849"
     CDS             complement(13973..15274)
                     /locus_tag="OUE31_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCU0222856.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(15566..16024)
                     /locus_tag="OUE31_001850"
     CDS             complement(15566..16024)
                     /locus_tag="OUE31_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCU0222857.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(16037..17367)
                     /locus_tag="OUE31_001851"
                     /pseudo
     CDS             complement(16037..17367)
                     /locus_tag="OUE31_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            complement(17378..18820)
                     /locus_tag="OUE31_001852"
     CDS             complement(17378..18820)
                     /locus_tag="OUE31_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCU0222858.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(18807..19571)
                     /locus_tag="OUE31_001853"
     CDS             complement(18807..19571)
                     /locus_tag="OUE31_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HCU0222859.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(19675..20550)
                     /locus_tag="OUE31_001854"
     CDS             complement(19675..20550)
                     /locus_tag="OUE31_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCU0222860.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(20805..20889)
                     /locus_tag="OUE31_001855"
     tRNA            complement(20805..20889)
                     /locus_tag="OUE31_001855"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20853..20855),aa:Leu,seq:caa)
     gene            complement(20907..20978)
                     /locus_tag="OUE31_001856"
     tRNA            complement(20907..20978)
                     /locus_tag="OUE31_001856"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20944..20946),aa:Gln,seq:ttg)
     gene            complement(20988..21060)
                     /locus_tag="OUE31_001857"
     tRNA            complement(20988..21060)
                     /locus_tag="OUE31_001857"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21025..21027),aa:His,seq:gtg)
     gene            complement(21122..21206)
                     /locus_tag="OUE31_001858"
     tRNA            complement(21122..21206)
                     /locus_tag="OUE31_001858"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21170..21172),aa:Leu,seq:caa)
     gene            complement(21227..21297)
                     /locus_tag="OUE31_001859"
     tRNA            complement(21227..21297)
                     /locus_tag="OUE31_001859"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21263..21265),aa:Cys,seq:gca)
     gene            complement(21343..21414)
                     /locus_tag="OUE31_001860"
     tRNA            complement(21343..21414)
                     /locus_tag="OUE31_001860"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21380..21382),aa:Gln,seq:ttg)
     gene            complement(21426..21498)
                     /locus_tag="OUE31_001861"
     tRNA            complement(21426..21498)
                     /locus_tag="OUE31_001861"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21463..21465),aa:His,seq:gtg)
     gene            complement(21501..21574)
                     /locus_tag="OUE31_001862"
     tRNA            complement(21501..21574)
                     /locus_tag="OUE31_001862"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21540..21542),aa:Trp,seq:cca)
     gene            complement(21581..21661)
                     /locus_tag="OUE31_001863"
     tRNA            complement(21581..21661)
                     /locus_tag="OUE31_001863"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21625..21627),aa:Tyr,seq:gta)
     gene            complement(21663..21738)
                     /locus_tag="OUE31_001864"
     tRNA            complement(21663..21738)
                     /locus_tag="OUE31_001864"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21703..21705),aa:Phe,seq:gaa)
     gene            complement(21774..21846)
                     /locus_tag="OUE31_001865"
     tRNA            complement(21774..21846)
                     /locus_tag="OUE31_001865"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21811..21813),aa:Asp,seq:gtc)
     gene            complement(21856..21928)
                     /locus_tag="OUE31_001866"
     tRNA            complement(21856..21928)
                     /locus_tag="OUE31_001866"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21893..21895),aa:Val,seq:tac)
     gene            complement(21944..22015)
                     /locus_tag="OUE31_001867"
     tRNA            complement(21944..22015)
                     /locus_tag="OUE31_001867"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21980..21982),aa:Glu,seq:ttc)
     gene            complement(22030..22118)
                     /locus_tag="OUE31_001868"
     tRNA            complement(22030..22118)
                     /locus_tag="OUE31_001868"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22082..22084),aa:Ser,seq:gga)
BASE COUNT         6974 a         4557 c         3530 g         7094 t
ORIGIN      
        1 aaactttatt gcgtgtttcc ttttttgttt attctcactt acctagcacc acgtataaca
       61 tactatagca atcatcatcc cacttctttg tcttttgaaa tactacgtta tttcttttta
      121 ttaacaaaaa acaatagcac taaacagacc aaaatagtta tgactctcaa cgcgggagta
      181 aacagcaatg ctatcattaa attagcaagt tcactgacga ttgaggaatt tgattcgtat
      241 aatacaaata aaggttctgc aaataaattc acatgtctat aaacaaattc tgtaaataaa
      301 tatacggtta agcctaaacc aattatggtg atattttttt tagattttga cattttttct
      361 ctcctataat aattttttca gttattcatt tcctttttta taaaaaatgt agattgtttt
      421 gaagtaataa tatgctgtag tttcaagaaa atttacagga aatttgataa ctgatattat
      481 ttactttttg accaccatat acatgacttt tatttttgtt tcttttttag aatcaaatgt
      541 gattaaatag aaaattttac aataatatgc acatataaat aataagatga tataatcaac
      601 aaagaaaatg tgattttttt cactatattt tatcacatga aaattcatta agaaagtagg
      661 aatcgaagta ttatgcacac accagaagaa attatggaac tcagtattca tcttggaaca
      721 aaaaaaatac ataaacctat cttagctaaa ctgattttag gttttatcgg aggagccatg
      781 atttctctag gttatttggc atacgtacga gtctctgctt ctatcccaga atctatggct
      841 agcttgacta gtttagttgg tgcctcggtt tttcctatcg gcctgctggt catccttctt
      901 ggcggtggtg aattgatcac cggaaatatg atggctgtgg cgattgcctt tatggataaa
      961 aaagtcacat tctcacagct ggttaagaat tggtcagtga ttacttttgc aaatattatt
     1021 ggtgcaattt tcgttgccta tttctttgga cactttgttg gtttaactca ttcaggtgtc
     1081 tatctcgacc aagtgattca tattgctgat cataaaatcg ctgtttcttg gtggcaagca
     1141 ttaggctccg gaataggttg taattggttt gtcggtttag cgttatggtt atcatatgga
     1201 gcaaaagatg cggccggcaa agtactaacg atttggtttc cagtcatgat ttttgtggca
     1261 atcggtttcc agcatagtgt ggccaactgt tttgtgatac ctgctgccat atttgaaggt
     1321 caagcgactt ggttagaatt tctctcgaat tttatccccg tttatattgg aaatatcatc
     1381 ggcggagcta tttttgtttc aggtttttat tacgttagtt ataagcatca ttaagattga
     1441 aggtaatgtt cattcgagca ttaccttcaa tctctttata tactatttat attttaagaa
     1501 caatagcctt ttattatata tattattcaa attagttata tcgagtgaaa aaaactttca
     1561 aattgattct ttttatttat cataaagata tagatacata atcattttca cttacatata
     1621 tttgaatatt aactaaaaac agcaagaaag aagaggatca aatgtattat gtagaagtaa
     1681 aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat cagtaacgaa tatcctttac
     1741 ttggttcatg gaaagaagct gctccttttt ccaaaccatg tgccataaaa ataaagaacg
     1801 agctagaaaa agaactgact tgtggcaaag ctgttgtaga tatcatcgaa aagtaaatcc
     1861 aatgtataga aaggaagatc acacatgaaa agcgacgtac aaattgctaa gattatagaa
     1921 ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt ataccatatg
     1981 attatttcaa tatgtatcct ggaattggag atctcgtaga gctatatcaa gatgaatcaa
     2041 atatacttgt cattcatcat gaaatataga gacttataaa attgtttatt tttataatgt
     2101 atcagtatag aaaggaaata aaacatggat tatactgttg aatttgacag tgaactactt
     2161 aagcaatttc cacaagaaga acatttcatg tataaagaag caatttccca caaagtgaca
     2221 gagtatttgg agcataattt ttttcgtata aagccagtgc gtactcgttc ggcaaaagga
     2281 atatacgaga tgaaagtcaa aattaataaa aaaaattatc gcatagcatt tgctttaaaa
     2341 aaaaatcatg tgttcatttt ttatattagt tcgaatttgc aaaaaattgt atttgataaa
     2401 gaggtgagta aaaaaataaa atagctgagc attggaggat agattgagtg atactaagtc
     2461 tatcctcttg tttttctaaa gaactaagct agaatttttt cttttgtacg ttattatatg
     2521 ttatttgtca ttaccaaaaa gcaccttttt tcttctagta tctatgacat aagaaatacc
     2581 acccatttcc tttacttgaa caaatcctac tgattcataa aatttttttg ttttctcagt
     2641 atcatctgtc aataattcga tttggactgg tccataacta gtgatcttct ccaaagcttc
     2701 attcaaaagc actttgccta ttccttggcg ctgatacctc ggatgaatga ggatatcttg
     2761 aataaatgcg atcgtcgcaa aatcagtgat ccaacgaacg attccgataa tcttcccttc
     2821 cccattacgc tttatcagag attcagattg ttcaaatgct ctagctaacc ttgcagtgtc
     2881 ttttgtgtaa ttcgtccaac caacgctctt atataattca gaaatctcat cgatcataag
     2941 ggaatcaata ttcatttttt tcttcctttc ttatacaatt ctccctctaa taatacagtt
     3001 ctttgactat ttaatctatc acatataact ctcctgtaaa gattctctcg attccttaaa
     3061 atctctcttt ccttttagaa tgcatccttt ttgataaata aaaaggttgt gataaatttt
     3121 cttcacaacc tctgtttctc tctatcaagt gttatctttt aattttctac ccttacccta
     3181 gcatctctat tgcccgtagt atgcatactt tccatgtttg cgaaaataat gtttatctag
     3241 taaatattgc gggatttcac atatattggg gttgatcagc tcgttttctt tggccatcag
     3301 acaaatttca tctaagatca aactgttttc tactgctttc ataggtgaat ccccccatgt
     3361 gaacggtcca tgtccataga caagtactcc agggacttcg tttggatcta attttctttc
     3421 cttaaacgtc tcgacaatca cattccctgt atgaacttcg taagcttctc ttacttcttc
     3481 tttcgttaat tggcgtgtac aaggaacctt accataaaaa gcatcagcat gagtcgtgcc
     3541 ataagctggc aaatcgcgtc ctgcttgcgc ccacatgacg gagtgcgtgg aatgagtatg
     3601 agtaatagca gttatatctt caaaagtttg atacaaaaca acatgtgtgg ggagatctga
     3661 agatggtttt aagctatctt cttctattat atttcccgac aaatctgtta ccaccatttg
     3721 atctgcttgc atgcattcat atctgacacc gcttggctta atgacgatga ctcctagctc
     3781 acggtccact tcactcacat tgccccaagt caatttgact aatccgtatc gcggcaatgc
     3841 cagatttgct tcaaggacac gttgcttcat tgctgcaatt ttttcttcac aagacatcat
     3901 agccagcctc cttcaattta gaacttaagt agtcttttgc ctgctggatt tctcttcgaa
     3961 agtcttggct tttttcactc cacatttcaa tcagaaatgt tccatcataa tctagacgtt
     4021 tcaaatgtct taataatcca agaaaatcaa cacaaccgct accaaaagga acatcacgaa
     4081 actggcctga atattctttt gttacagggt aagtatcttt taagtggata gcagtgatat
     4141 aatcgatccc tttctcaagt tctcgagccg gattattttc cggccatgcg gacaaattgc
     4201 ctaggtctgg atatacttgt agaaaagggg aatgaatctg ttctttgatt tctaaaaatt
     4261 ttgaaatgga gttcataaat ggatcatcca tgatttccac ggaaagaatg atgccatatt
     4321 tagaagcttc ctttacgctt tcttttattc cttcgataaa gtcttctctg gaattcattg
     4381 atttctcttc ataataaaca tcgtatccag ctatttggat tactttgacg cttagattat
     4441 gcgccaaatg gattgctttt ttcattagtt gtttcgctgc ttttttcttt tctggatcag
     4501 cagaaccaaa cggaaatcgc cgatgcgcac ttaaacaaat cgaatggata cgtacaccgg
     4561 agctgaacat ctcttctctc agctcagcta tcttttcttc agaccaatct aatcgtgcta
     4621 accgctcatc cgtctcatca atcgacatct cgataaaatc gaagtccatt tcttttacaa
     4681 gggaaaaacg ttctttccat gaaatatctt tgggtaatgc tttttcataa atcccaattt
     4741 gagccatttc cttaccccca gatacgaatg atctcatctt tgaagttttg tgcggccttc
     4801 atcggatcat ttgctgctgt aataccacga ccagtgataa aggtatacac atcgatccct
     4861 tcaaataagt gtaatgtgtg tggatttaat ccaccagtta cagaaacatt aaagcctagt
     4921 tcaatcagtt ttttgatctt cgataaatct ttttcacccc aagtttcacc agataacagc
     4981 gcatcacggc tttgatggta gattacctgc cggataccga tgttatgcca atccatggct
     5041 tgttcaaaag tccaattgcc gtagagttct acttgcaatt cacctatttc tttttgtgct
     5101 gcctccatag ttggaatcgt tgcacaacaa atgactgtca tccagtctgc tcctgctttt
     5161 gcaacattac tcgccactgt tcctccagcg tctgcacatt tcgtatcagc gactagtttt
     5221 ttatctggga acatactgcg aatacagcga atcgcttttt gtccttcctg taagcaaaga
     5281 attgtgccca cttcaataat atctactaca tcaccaactt tcataacatc tcctaatgca
     5341 tgttctaagt cattgtgatc taacgcaatt tgcaaattcg gcctgctcat cttagttcct
     5401 tcctttactt gtttttttgg taccactttg tttcagcaaa tttttcactg atttctttgg
     5461 ctgacatcac atttttgata ccgataactg taacttcttt tttctctgcc tgagtaaaca
     5521 tattcaaaaa attgactggc gtaaaaacta catcgtattg gccagctgaa ctttttccct
     5581 ctgaaatggc acaatgatgg attttggtaa ttggtacgtt tagttctttc attgcttttt
     5641 ccacacttct catcatcatc aagcttgttc ctgatccatt tgcacacgat actaaaattc
     5701 tcatcttaat ccctccatta tgagtgttgt ctaatcagat tttcttttat actctctgct
     5761 tttctgcata tgtgtcatag tcttctacaa tcaaaaaata accctcagga tttttccgat
     5821 attgtaactg cggaatagcc aataaaccaa tgacaactac ggcaattcca gcataaccta
     5881 ggactttcat gattactgta aacaatggcc aagctgttgc ccagtcgaac atcccgatat
     5941 aaccaccata tgttgacatc ccaatccatg tagcgaataa tgctgaaccg cctacttgta
     6001 tgattcctga aagaaacggg aacaggcaag cggctttgaa tccacctcgg ttattggcat
     6061 aaactgctat aacggcatta tcaaagaaca acggaatgaa accggctatg acgatcgttg
     6121 gtgatttcaa taaaatcagt aaaccaatca tcaaaaactg tcccaaagca ccaaacaaga
     6181 acccaatcgt taccgcattt ggcgaaccaa agccaaaagt agcagctacg tcaattcctg
     6241 gaacagctcc tggtaaaatt gtgtttgaga ttccttggaa agattgagtt agttcatcga
     6301 cgaatgtccg aacacctaat tgcaagatcg ccagatatac cgcaaaattt aaagaagtcg
     6361 tcataatgta gaataagaaa ctctgtcctt cttgcatgaa ttgcgcttga atcaaataat
     6421 ctttgcctag tacaatcaga atgatcccaa agaaaaatag catgagtaac gaagtagcaa
     6481 ccatattctc attgaaaatc gacaagaatc ctggtaattt gatatcttcg atttttttgt
     6541 cttgcttgat tgatctattt ttcttttcat cccgcttttt catccactca gctaattttg
     6601 caaatataaa gattccgaac atttgctgat gtgccactgc aaatccggca ccttctgtca
     6661 attcctgcgt gattcctact gttaagttag aagctactgc ccaataacaa cctaaaatca
     6721 gtcccataaa aatcaatact tgtatcctac ctagatcagg aaagcaaaac agtaaaatcc
     6781 aaaaagcggt agctgcttgt tgaacctgaa cgtttccggt agtgaaaacg gaacgcagtt
     6841 tcgtatattt ctgaaaacgg actaataaga tatttaaaac aaatgcaatc agtaataaaa
     6901 tcatcacatc tccaaaggta cggccaaatg tctccattaa tccagcatcc acagcatttt
     6961 gtccaaaata aggatctgta accatggcat ccaaattgaa ccgttccttt agtccaacca
     7021 aaatcggccg aaaattattg accaaaccac cagagccaac agtcaaaata aagtaaccga
     7081 ccgttgcctt taagaatcca gcgatgcatt catgaagcgg gcgtttcagc aaaatatagc
     7141 ctaataacac gataaaacca atcaggtatg ctggctgcgt caagatattt gttgcaaaat
     7201 acgtccaaat gcttaacaaa aattccccca tcttttttct cctctatcaa ttaattatat
     7261 tctgccatca caacttggta atcatcgatg gagttcgtag agatgagacg ctcaaccaat
     7321 ccatctgtca ttaataattc ggataatttt tggatatttt ctagatgttc ttctggatct
     7381 tttgctgcaa gtgtaaaaaa caaactagcc gttttctcct catcctcccc ttcactttca
     7441 aaacggattg gctgtttcaa cttggtaaat gaaatagctg ttccaaaaac accatcactt
     7501 ttttctgaag aatgcggcat tgctacttga ggtgcgatca caatataagg accgtatttt
     7561 tctacacaat ggatgatctc ctccacatac gtttcatcaa taatttcctt atcgatcaat
     7621 acaagacagc tttcggcgat agcttcacgc caatccgtga tttctttatc tgggtaatga
     7681 atcaattgat ggtcaaaaaa gtatttcagc aagaaactcc ccttctttct tataaaaacg
     7741 acggaaacgg tgtatcattt tcaatcgaga agacatcttc aaatcctcga taaaaattaa
     7801 actcaagatc atctttgttt gtcggataga tgaatttccc gcctacttgc cagatataag
     7861 gtttaaatcc atacttcagg cgatcctttt tgaatttcca aatttcagtg atctcttttg
     7921 aatcagccat aaaattagac caaatatcgt agtggacagg aatcactact tttgcattca
     7981 atgactccgc catgcgcagc atatcaacag aagtaacttt gtctgttatc cctcgtgggt
     8041 tttcaccata ggcccctaaa cagacatcga ttttgtgttc attaccatgt ttggcaaata
     8101 aattggagta atgtgaatct cctgcatgat aaagattccc tcctgatgtt tcgaataaat
     8161 agtttactgc aatttgatcc atctcctgag gcatttttcc ttttaatacc tcttctggat
     8221 cttcacaagt gaccaacgct gtccgatcaa acgcttctaa agctactaca ttgatgtctt
     8281 tgattttgac tgcatcacct ggctttactg taatcgtttt ttcttcagga attccccatt
     8341 tttgccacgt gcgaaccact tcttttggcc caatgaatgt tgcttcagga caattttgat
     8401 gaactgctgc ggctgtatgg atatctagat gatcggaatg gatatgtgta acgattaaag
     8461 cgtctacatt ttttatcgca aaaggatcga ttacgaaagg ctgagtacgt aaattaggct
     8521 gcatattttg aacgccactc atacgcatca tctgatggcc ttttttcatc atgccattcc
     8581 catgactacg ttttcccgtc ccacaccata gatcacataa aatattcgtt ccttcatgac
     8641 ttttcagcca aattcccgta cagcccagcc accacatagc aaaagttcca ggatccacta
     8701 cttctgtttc gatttcttca ttcaagtatg tgccccactc aggaaatgtt tctactaacc
     8761 acttttcttt tgttacttca ttgacagttt tactcatttg cttgctcccc ccatatcgtt
     8821 gttccaactt acaagtaaat attaatgtgt atcagcatcc atggaaaccc ttttatatga
     8881 ccgtttgttt tttatatgat tttctttcag taatcaatga ttgtttcagt ataataaaga
     8941 cagatatgaa tgtttaaatg aacaactagt caaataaatc catggatcaa gatgtccctc
     9001 aggaggcaaa agtcatgaaa aactcacttg tcaatattga aaaacgtcaa aaagaaattt
     9061 tggaactgct tcagcagact gaacaactat caactttcga attagctgaa tcccttgatg
     9121 tatctattag tacgatacga agagatttaa atttattaga agaaaaaaac gagatcatac
     9181 gcaattacgg ttattgttct tataattaca aaaaccagac tgattttgat caatctggtc
     9241 ctgaaaggat taaacaagcg attgccagag aagctagtaa atacattaac gattatgata
     9301 cgctgtttat caattctagc tcgactgcgt tgaaaacact ggattttctt caatctaacc
     9361 atttgacagt cattacaaac aacgtgaaaa tcaattactc tccgcacaaa gataattgta
     9421 gttatatttt aactggtgga gagatgcgct ttccaaaaga agcactagtg ggcgacatcg
     9481 cattaaatac gatttcttca gtcaatgcag acatttgtat cattggctgt agcggagtcg
     9541 atgtagtaca tggggtcaca acaaagatat taaatgaatc aacgatcaac gaaatgatgg
     9601 tcaacaagac aatcaaatgt aagattttag tcgctgatca tcgaaaaatc ggactgacat
     9661 caaagttcaa gattgctgat atttcagtct ttgattattt gatcactgat aaattttgtt
     9721 ctgaaaaagt attagaggag atcagaaata cggggataaa aaccattcaa gtagattcat
     9781 tttaagaacc aggacgtaaa tatgtaaata ggattatcaa aaaaatgaat aacaaattta
     9841 tcgataaatg aaaaacacgc tacgctcaaa ttgataaagg aatcccaaga tgtgtccatc
     9901 caatcgatac catcataatc tattgcttct tttataaccg ttatatgttg cctaaatagg
     9961 aatcaaacaa tatcgaaaaa aggaggtatg acaaaagtca cacctccttt tttcgaataa
    10021 acggtattca aatcagaaca ctgatttcac aaccacttta tttcaggtcg ttttcaatca
    10081 cctttaccgc gtaatcattt ccgttgaaac gcgctatttt ttttgcgtcc atatatcttt
    10141 ctaaataatc atcttctcct aattgcttat ggcaagaagc aatttcataa agcaagtatt
    10201 ccaatgcata agtcgattta tgtttcttat tatactcaat acccttctca cataattgga
    10261 ttgctttatc ataatcctcg attttacggt aataggtggc gatatcataa tatacaatgc
    10321 agaccatcag attatcaaaa tcagtctcac tcaatatttt aagtgtacgc tccacataaa
    10381 ctttcgcaaa atctaattct ccttttgaca agtagatcat tgccacgttt gcagctgctt
    10441 gtaagtgatg gatatctgtt tcggtcgttt gttccaacac ttgattaaaa taaaataatg
    10501 ctgcatctgg ttttttcgca taaagatgat caagcagtcc ttgataaaat aaaatttgat
    10561 ttaaaagatc agaattactt actttttcct gatcgatcgt ttgtaaaatt ttataagatt
    10621 cttggtattt tgatacagaa ttcaatgatt gaatctcatt tatttttttc ctgattttgt
    10681 cttcttctgt ttctactaat atatcggaga tctcgacatt cagctttttg caaagcgcac
    10741 ttaagatatt gatgcctggc gacatattct tgttttcgat attgctgaca gttgcttgtt
    10801 cacaaatgcc ttctgctaat tgtacttgtg ttaacccctt tttctttcgg tattctttta
    10861 gtaatgctcc atctacttta atcaaaacaa tttccttccc tttaaaaaat tatttctcct
    10921 ttatatcata cacaaaaaaa agttctaaac aaccaaaaat gtttagaaca gaataaaaat
    10981 tttaatttta aaataatatt caaattaaac aactggcgta tctgctcctt gatttctttt
    11041 tgtgttatct gaataattat cgtttacagt tataacacat agtgaaaatt gtcatggcga
    11101 gaaagtctaa gaatattttt aaacataact atttctttct tacgtgtgta taatgacgac
    11161 agcacaccta tcaattaata taattatttt attttttatg ttctcatgtt tatttttaat
    11221 gacacaactt ctcgtattta tctggcacaa catataaatc gatcaaaaaa ttgttgcgtg
    11281 tttttttgaa aattggagtt tcaacttgat tacaaaattt aaatttagaa gttgtgaaaa
    11341 cagcgagaga cagtttaata ttcaaaatat acataggcta ctcgaacgct gtgtttttta
    11401 gtatactagt aagaaacgaa gggatagact cattccaata aggaggattt catgaagaca
    11461 attctttttg ctcctgcagt attcaattta gctgagacaa cacgaatgat tgaggttgcc
    11521 aaagctatga aagaccgtta ttactgtgta ttctttggct tttctaaaac ttttgctcct
    11581 ttgatcacag aaagtggctt tgagtatcat ttactagcgc cgatccttac gaaaaaacaa
    11641 gaagaacaaa tcataaaatt tgaccagttg cgtacactta aaaacccttt taccaaagaa
    11701 atggttgcct ctcgtatcac tagtgaacag agtctgattg ctaagtttga gcctcgactg
    11761 attgtgacag gttcgaatgt gacaattttt ttatcggccc gcaataaaaa gattccttta
    11821 gtatatgtta aaccctatgc tttgagtgaa cctttttttc aatcagagca tgcgctgatg
    11881 ccccacgagt tacgtttctt cggcccttta agcaatcccc tttggcactg gacaaaaaag
    11941 cgtatagtaa atacccgatg gatccccaat gccttcaaac acgctgcaca aaaagaaatg
    12001 cttcctttac caaaaacaag tttacaaatg atggatgctg atctaaatct catcacaacg
    12061 cctaaactat ttttggaaga agaacagctg ccggaaaatt atcgaatcgt tggtccaatt
    12121 tttgctaagc tcagtacttc cttgcctgaa gaagtgctaa cttttataca gcgaaagcaa
    12181 caagaaagaa aacgtattat ctatttcgca atgggtagtt caggcaatcc gcgtatgtta
    12241 cgcaaaattt tgttcttctt acaaaaacaa ccggatctag cggttattgc acctattgac
    12301 tatctgcttg atgacattca atctgactca gaagatcttt taataacaga atatctgtct
    12361 agtcatcttt tgcatgaatt cattgatttt tcttttatcc acggcgggga agggaccgtc
    12421 caaactgcct gtgaatccgg caaaccgttt atcggtgtgg ggatgcaatt tgagcaaagc
    12481 tgtaatattg actattgtgt aaaatacgga aacgcaatcg ccctcacaaa accagtgact
    12541 gaaagaaaac tgcagattgc tctgcgcgaa gtttcttcac ccaagattcg tcagcaggca
    12601 cgcacgctgc aagccgtttt tccaataaat ggtccacaac aagcaattca agaaatcgaa
    12661 accttcctga gcaaccaccc aatatagttt caagtagaaa aagctttttt aatagagact
    12721 catcagtaat ttcgctattc gagacccaga cagtgaaaat acaaaaaaag taaatagtgg
    12781 attgaaaagt tagagttact taaattacgg tgtctaaaaa acacaaaatc atccttaaaa
    12841 taaaagatct gacgcaatcc aaatgagcat aggtagcgtc tgccatttat tcttagtcaa
    12901 attctttgac acctttctct ggttggatca tctcaacgtt tcttcaaaag aaagaccata
    12961 ataattaggc aaatacattt tcttaaaatg tgtcatatag atctagaagc atcgctttgt
    13021 agagatttgt gctgctagtc ccttcaacaa ttactaaatc aaatgtagga tttaccactt
    13081 tatctttgat aatcaacctc cctcttctgt tgagacaatg atctcgcaat ccgatgcata
    13141 ctcctatata aactgccagc aatccccaca tgctgagtag atcatgtcag aatgttctat
    13201 gtcgtcagca acgataaact aaaagtcacg ttcaccatga ctgattgcta ttcccagcgc
    13261 aattatttct atacacgttt catgatttga ataaacactc tcatcataca tattaccatt
    13321 catacaccat actgcagccc ctactatatg gttgtaagct cccaaatcta tatttgcctt
    13381 gatcactttg gtagtagatc gactaattct taatccattg ctgataaaat tttcattttt
    13441 gcctccttct ttctgccaaa acagttaaaa caataataat ctttatgtaa aaaagggctg
    13501 tgacaaaagc cttgtcacag tcccatattc cgaataaacg gtggtcaaaa gcttgcatct
    13561 gcggtaataa gttcaaccaa acgaaaaata agccaacatt tcacaaaaat ttaagaagca
    13621 attttcgtaa atttcttctt atttcttgaa gctaaccact tctgtcacaa ccacttttag
    13681 aacatttaaa gcttcgatgt gacaaaccat ctatgctgct cgatcataaa attgatagca
    13741 aaaattccac aaagtacata tgtcccccat gaaaacaaaa cattcatatg cggtacaatg
    13801 atctttggaa gaatcacgat caaaaatgat gccagtgccc aaatccatcg attgatttga
    13861 atatgatatg tagctagcat attcaatata aggtgactag ccgttaataa aaagataaaa
    13921 acaaaaaata aaatcagcca atacattgtt tcccaccttc taaaaaccaa acttagacag
    13981 tttggacttc gttttctcca cgactttgtt catctgacag catcttttta tcataagctt
    14041 ttacaaatgg ataatagata ataaatgcta tcaatgtgtt gatcatgatc aagataacaa
    14101 cacgccagtc atttcctgct gaaagataac cgccgattgg agctggtaat gtccaagttg
    14161 gcaaaacagt aaatctattg accatttcta atttgactgc aaaataactg ataatagtca
    14221 aaactaaagg aactaagttg aacgggatga acatgtaagg attcaacatc ataggagctc
    14281 caaaaatcat gggctcattg atattgaaga taccaggaat aatagaaaaa cgaccaacct
    14341 ctttcaagaa ttttgattta cagaagaata taaacaaaac agataccacg atcgttgctc
    14401 ctgcaccacc aattgttacc gtccattgat aaaactgttc aggagcgata tagggtaatt
    14461 gggtggcagc tgtaccatct gccaatgcct ttgcattctc atccaacatg atcagccaca
    14521 ttggacgaac aacagcccct acaatactca tgccatggat accaaatgac cacaacaaat
    14581 ggatcaaaaa cattggtagt aaaacaccaa gcaaattatt ccctaaaata ttggttaaag
    14641 gctcgaataa cgataataag gtagcgttta catcaaagcc cgcgacgctt cgaatcagcc
    14701 aagtaattgt taaaatgact gcacctggaa tcaatgcctc aaaactacgg gcaacagcag
    14761 gtggcacttg ttctggcatt ttgatagtaa tatttcgatt tttaaagaaa cgatatactt
    14821 ccactgcaaa aatcatagat aagatccccg caaacatccc agatgctccc aaagaactca
    14881 taggtaagac ccagccaaga ggtgcctttt caggagttaa aacgtttaca ggaacttgta
    14941 acataaagaa cgttcctaaa gataatatac cacctgtcac actatctaat ccatatgatt
    15001 tagctagatc cgaacccata acaaaagttg cataaatagc catcaatccc atcgtcatcc
    15061 taaaaggtaa aacaatcgtt gccgaataag gggcaataaa ttcattccat ccaggaaacg
    15121 gtaaattgat aaagaccata aaaaatgtcc caatcaaaat caatgacaat gttgaaacaa
    15181 ccccattacg aattgctaat aaatgacgct gtgtaccaat ttttgccatt ggtgggacaa
    15241 gtttctcttc gacccatttc atcagctttt ccactaaaac cactcctttt caataaaata
    15301 tgaaccattc attgcatgac aacgcaaaga atgttcataa ctaattatat aattaagaaa
    15361 ttttatttca atatattctc ttaaataatc aaatttattt ttaagaatcc tgaaaataag
    15421 ttttctaaat cataggagca acaaaaaaat tcgataatta acaaaaatca aaatgattaa
    15481 atctagtgat tgaaacttat catttcaaaa aaattttgta aattcaccca taaatatcac
    15541 cctatttaac ttttttcatc gtacactaaa attcaaaaca actatcttta atctttactt
    15601 cttggttttg ttttaataaa tttccttcaa aaatgcctgg agaaactaca atgatcaccg
    15661 tatctttttg tgcttgctcc aacttcttca aatctataat agctaacagt gtcccttctt
    15721 ttacctcctg gttactttca acccgtatct gaaacggact tccttcgagt tcaactgtat
    15781 ctaaacccat atggatcagt atttttctgc cagattcact ttcgatcgtt atggcatgtc
    15841 gggtaggaaa tatattatcg attattcctt taactggcgc atggatatat ccatcatgat
    15901 tcgttatagc gtatccaact cctatcattt ttgaagaaaa gacctcgtct tttactgctg
    15961 ttaatggaat aatttgacca ctagctacag cttttagaat gtttcttgtt ttaaagaaat
    16021 gcacttttta tcacctctac tttaatgctg gccaatattt tttgtttact ttgatcattt
    16081 catctagtat tttttttgcg actctggcat ttggtacggt ttgattcaat gtaaatgctt
    16141 gtaaagcttt ttgataagaa ccttcaaagt aagcatctac tagtaacttc tctgctgcaa
    16201 cttgtgcctc catcaatcct ttatgaaaat cactgattgg ttttcttagt gtaattgtct
    16261 ccacaccagt tgcaccaaca tatgccggta tttcaacaac tgcatctgac cgtagattcg
    16321 gaatcgcccc ttgattagga acgattagca taaagcgacg acgatcatca ttcaacaagg
    16381 aaatagctat atcgacgata tattgtccat gctccccaaa attaaagttc aatacttctt
    16441 ccacaatacc gcggcgtatt ttatcagcca tttctttggt atttttctct cgtccatcca
    16501 tgaccatatt agcacgtgta tactctttgt cagtatgctc aacgaccata tcaggatata
    16561 agtaatactc taagtaatta ttcgggatat tacttggaaa atttttcgtg atgactgaca
    16621 tcatttgaaa ggttttttgc caagttttgt ctcctatatt aaaatcggcg acttgcattt
    16681 cttttgttat tagtttttca ataatctctg gcataatttc tcgttgcaat tctttatcat
    16741 aaatcgatgt ataccagcca aagtggttta aaccataata cgtaacgatc caattcttac
    16801 gatcataacc gtaattcact gcaatcgttt cttcaattga aatagtcata tcacaggcat
    16861 taatcatttt tacattcgga tatttacgac gaacagcttc agaaacgatc gactctggat
    16921 ttgtataatt caaaatccat gctttggggg catagtcttg tatatgatcg acaatttcca
    16981 ataaaccttt gattgagcgc atcccataag caaatcctcc gagtccacac gtttcctgtc
    17041 ctactaatcc atgtttaagt ggaatctttt cgtccttttc tcgcatctcc aatcctccaa
    17101 cacgaatttg tgagaaaaca aaatcgcatc ctgtaaaagc aagctttgga tcatccgttg
    17161 cacgaatgcg aatatttgaa aaaccttttt tttcagcata aatttaacaa tcaagtacat
    17221 atccatattt ctttcttcat caatatcata taaacgtatt tcagataatg gcaaccgttt
    17281 ttcattgttc aaaatggctt gaacgattcc tggtgtatac gtactcccgc ctccagctat
    17341 agtgataatc tgttttttca tcatcatctt ttcctttcta ttcttctaat aatttattga
    17401 attctgccat aacataagtc acttctaagc cgatgataat ttgataattt ttttcagttg
    17461 gtttaatgat cccgcttatc cctaattgct tgattcgctg ttcctcgacc atggtgggat
    17521 ccactacctc tacccgtagg cgtgtattac aactatagac atccaggata ttggcttttc
    17581 ctccaaacgc ttgtagcatt tttgttgcca tatattcata atttttactt gctaacccta
    17641 actctgtttc ttctaaggtt acttcattgc caaactctgc cttagcttca cgtcctaatg
    17701 tctgaatgtt tctcttattg atcaaataat aaaaagtaac gtaatacaag gcaaaaaaga
    17761 aaattccgat tggaagaatc aaaatagcat tggtagcgat tcgaaaattg atgagataat
    17821 caacaataca tgctccgaat gtaaaaccaa ttcgtatatt gaataagtaa cagacaatcc
    17881 ctgctaaacc ggcaaaaagt gcatggatca cgtacaacat aggagaaaga aacatgaaac
    17941 taaattcaac aggctcagtg atatttgcaa taaatgaagt tcctgcaccg cttcccatga
    18001 ttcctttgac catctcttta ttttctttat aagctgcttt atagatagct agacatatag
    18061 ctggtatacc aaacatcatt actacaaaaa aacctgataa aaacagtcca gcctgaggat
    18121 ctccgttgat aaagcgtgtc atctctcctc tgaaaacttc cttgctagga gatgtatagc
    18181 ttcctaaatc gtaataaata tacgtattca acacatggtg cagtccaaag gggatcagca
    18241 aacgattcaa aaacataaat atccccacac ctaatgcccc catatcaacg agcagttttg
    18301 caaaattatc aatcccaatt tggatgagcg gccagataaa gcccaaaaaa atagctgcga
    18361 ttgtttgtag aatcatcacc atagtcaatg ggaatttttc gcccgcaaaa taagaaaaaa
    18421 ctactggtaa tttttgttct ttaaagcgat tatacgtcca tgccgctact aaaccggaaa
    18481 taattccacc aaaaatcccc atattcactt ctgggtccat gatttctaag ccttttttca
    18541 aggtagcaat cgctaaaaaa ccagtaagtg caggtattcc tttgtcctta tttttgacaa
    18601 aaccgattgc aactcctata gcaaataaga tatccaagtt tccaaaaacg gcatttccag
    18661 ctgcaccaat tactgggatg ttcagcatat catcagctga taaacgcatg atcaatcccg
    18721 ctaatggcat cgctgcaact ggaagtagca tcgctcttcc aagcttctgc acatttgatt
    18781 taacattcat ttttattcct cctctattaa atatcctcat atgttactaa ctcaatcaaa
    18841 ggatcatttt tcactttttg agcaaatgct gaatgaatta aaaattcgac ttggtgagta
    18901 cgaggataca caaaacttga accatttaac aattcctgat ccaaatacgc tgcgtgacac
    18961 atgacttcga tcgttttatc ttctctcaat atcatgagta aacttgccaa atattcttcc
    19021 acactcgtat tgatttgtcg ttttttttca tcagtttctc ctacgacatc gaaacaaggc
    19081 tcaaaataat cgacatgacg aacttcatct tttcgttcaa agttgctccg aaccggcaaa
    19141 tcatattttt ttgctaatgt aacaactacc tcctggtttt catccaaagt atgagtatga
    19201 tgatgactgt ctaaatgagt tggtatgatc cccgcatgat aaattttttg aatctgagca
    19261 ttccattcct gatacagttg atctttgtca atgttaaatg gatgctgata ataagataag
    19321 gatctgaact ctccgctttc gataagagta tcgacagttt tgagaagtgg tttgccacac
    19381 gtcaatgtta aatggactcc tacacctagc ctaggcattt cctttcttag tttcacagcg
    19441 tgctcgaaac ccggcatatt tgccatcaat gtagttgatg tcaaaattcc tcgctgataa
    19501 gcatccataa tcccataatt cacaccatgg ctatagccaa aatcatccga attaaaaatc
    19561 acttttccca tttcattctc cttctttttt ctactaaaat aggcgcaacc aaataatcat
    19621 agtccattta ctatgtgtca tttggttgcg cctatagata gttacgccct tattttaata
    19681 gattcgtgct agatgaattg ccaaatagat gatttcattt tcttgaatgg caagttgaaa
    19741 ttgctgttcg atgatatctt taatctttag tgctgtacaa tacgctttgc tatgtttaaa
    19801 tgtttcagta aaaaaaccaa tattttctac tggcgtttct tcctgataaa tcaagcgttt
    19861 aaccaggaat ttgatatgaa ccattaagcg atgataagtc agtgattctt tatcataaac
    19921 gtttgaatag gatttttcta gatgggacaa aatcgtggtc gtcatttcta ctatttttaa
    19981 gctctttaaa ctattaggct ctcctagctc agcattaatg atatgcatag tgatgaatcc
    20041 tacttcattt gaccctaact cggtttgata tcgatgattg attcgctcga ccacttctat
    20101 tgctatatca tattcatttg gataaaggaa tctcatttct ggcaacataa ttgctgtgac
    20161 atctctatct tctctttttc gttgaatagc aaaataaata tgatctgtca atgtaatata
    20221 gatatttgaa tctaatggag aggagatcct agctgttatc agttcaatca cttcttccgc
    20281 aaaatccata aattcgattg gaatctgcga gactatctca ctgaatcgtt tgatcttttc
    20341 tttagaatct aatacaaata atttgtcagc atcctcaaca tcaaatggct tactcacttt
    20401 agcagaaaag ccaatccctt tccccatcgc aattttttct attccatcgt catcgatcaa
    20461 tacagcatta tgattcagct ttttcatcac atacaccgtt aattcacctc cactatatga
    20521 taaaacaaaa caacttgcag actccttcat acatattttt gtctccaaac aatttttaaa
    20581 gacaaaaaac gacctaagaa agaacccttt cttaggtcgt gcctaattga atagtagcac
    20641 cctacataat ttacaaaaat agtttaacac ataataaaag cgttatcaat atctttttta
    20701 ctcgttttat gataatactt gtatcgaatt gatttggagg taattacata aaaacaaaaa
    20761 aaatatagca actctctata agaaagttgc tatattgata attataccgg cggccggggt
    20821 cgaaccggca cgtcctcaac ggacactgga ttttgagtcc agcgcgtctg ccaattccgc
    20881 cacgccggca aatttaaaaa taataactgg ggtagctgga ttcgaaccaa cgcatgaggg
    20941 agtcaaagtc ccttgcctta ccgcttggct ataccccaag aataaagggc gaatgatggg
    21001 aatcgaaccc acgaatgccg gagccacaat ccggtgcgtt aaccacttcg ccacattcgc
    21061 catcataaaa gatgttattt aatttctcaa taaaaaacta agatgaagac atcttagtca
    21121 ataccggcgg ccggggtcga accggcacgc cctcaacggg cactggattt tgagtccagc
    21181 gcgtctgcca attccgccac gccggcaagt tgatttatta gtactaaggc ggtaaccgga
    21241 tttgaaccgg tgatgaaggt tttgcagacc tctgccttac cacttggcta taccgccatt
    21301 atactattat caatctacaa aataaagaat aaattataga aactggggta gctggattcg
    21361 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaagaata
    21421 aaaagggcga atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa
    21481 ccacttcgcc acattcgcca tggcaggggc agcaggaatt gaacccacac taacggtttt
    21541 ggagaccgct gttctacctt taaactatgc ccctataaaa tggaggagag tggattcgaa
    21601 ccactgaacc ctaaggaacg gatttacagt ccgtcgcgtt tagccacttc gctactcctc
    21661 catggtggcg cgggacagaa tcgaactgcc gacacacgga gcttcaatcc gttgctctac
    21721 caactgagct accgcgccat attttaaaat tattaattga ataacaagaa cgacggttcc
    21781 gacgggaatc gaacccgcga tctcctgcgt gacaggcagg catgttaacc cctacaccac
    21841 ggaaccagtt cattatggag gttaacggga tcgaaccgct gaccctctgc ttgtaaggca
    21901 gatgctctcc cagctgagct aaacctccaa cattcaatta aaatgacccg tacgggattc
    21961 gaacccgtgt taccgccgtg aaagggcggt gtcttaaccg cttgaccaac gggccaggta
    22021 aatttgctac ggagagtaag ggattcgaac ccttgagaca gtttgcacca tctacatgat
    22081 ttccaatcat gctccttcgg cctctcggac aactctccag agtgaaagaa gctcaatact
    22141 ctttctcaaa atgag
//
LOCUS       DAKCAA010000045        21858 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000045 DAKCAA010000000
VERSION     DAKCAA010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.045"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(65..376)
                     /gene="rhaM"
                     /locus_tag="OUE31_001869"
     CDS             complement(65..376)
                     /gene="rhaM"
                     /locus_tag="OUE31_001869"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HCU0222861.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(378..1223)
                     /gene="rhaD"
                     /locus_tag="OUE31_001870"
     CDS             complement(378..1223)
                     /gene="rhaD"
                     /locus_tag="OUE31_001870"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HCU0222862.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(1237..2493)
                     /gene="rhaA"
                     /locus_tag="OUE31_001871"
     CDS             complement(1237..2493)
                     /gene="rhaA"
                     /locus_tag="OUE31_001871"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HCU0222863.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(2490..3950)
                     /gene="rhaB"
                     /locus_tag="OUE31_001872"
     CDS             complement(2490..3950)
                     /gene="rhaB"
                     /locus_tag="OUE31_001872"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HCU0222864.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            4103..4972
                     /locus_tag="OUE31_001873"
     CDS             4103..4972
                     /locus_tag="OUE31_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HCU0222865.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(5098..5997)
                     /locus_tag="OUE31_001874"
     CDS             complement(5098..5997)
                     /locus_tag="OUE31_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222866.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(6162..6986)
                     /locus_tag="OUE31_001875"
     CDS             complement(6162..6986)
                     /locus_tag="OUE31_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCU0222867.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(6997..8292)
                     /locus_tag="OUE31_001876"
     CDS             complement(6997..8292)
                     /locus_tag="OUE31_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HCU0222868.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(8308..8787)
                     /locus_tag="OUE31_001877"
     CDS             complement(8308..8787)
                     /locus_tag="OUE31_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HCU0222869.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(8793..9821)
                     /locus_tag="OUE31_001878"
     CDS             complement(8793..9821)
                     /locus_tag="OUE31_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HCU0222870.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(9838..10944)
                     /locus_tag="OUE31_001879"
     CDS             complement(9838..10944)
                     /locus_tag="OUE31_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCU0222871.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(11173..13770)
                     /gene="adhE"
                     /locus_tag="OUE31_001880"
                     /gene_synonym="adhC"
     CDS             complement(11173..13770)
                     /gene="adhE"
                     /locus_tag="OUE31_001880"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HCU0222872.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(14075..14455)
                     /gene="yajC"
                     /locus_tag="OUE31_001881"
     CDS             complement(14075..14455)
                     /gene="yajC"
                     /locus_tag="OUE31_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HCU0222873.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(14552..15697)
                     /gene="tgt"
                     /locus_tag="OUE31_001882"
     CDS             complement(14552..15697)
                     /gene="tgt"
                     /locus_tag="OUE31_001882"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HCU0222874.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            15915..16613
                     /locus_tag="OUE31_001883"
     CDS             15915..16613
                     /locus_tag="OUE31_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCU0222875.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(16781..19420)
                     /locus_tag="OUE31_001884"
     CDS             complement(16781..19420)
                     /locus_tag="OUE31_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCU0222876.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(20039..21070)
                     /gene="queA"
                     /locus_tag="OUE31_001885"
     CDS             complement(20039..21070)
                     /gene="queA"
                     /locus_tag="OUE31_001885"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HCU0222877.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            21263..>21858
                     /locus_tag="OUE31_001886"
     CDS             21263..>21858
                     /locus_tag="OUE31_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0222878.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         6181 a         4840 c         3848 g         6989 t
ORIGIN      
        1 ttgtattatt tttcacaata aaaacgaaag aaccccaagc aaccggttgc ccagttgctt
       61 gttgctacag ttcaaagact ggcatcaatt cccaactgac tggagaggca tctggatttg
      121 tctccatgat atcttccatg tacttccacc atttttgatt gatagatgta tttgccattt
      181 tttcccataa cttttcatct tcgatcacta agtaaccaaa taacaaactt gtactcggat
      241 caagatagat cgaatagtcg atgaccccgt gttcacgaag tgctgtacgc atttctggcc
      301 aaagttcatc atgtcttttt ttgtattctt cttgtttttc tgggtaaact ttcatgcaaa
      361 aagctttttt caccatgtca gacacctgct ttcgtatgaa cttcctccaa ataacctgct
      421 tttggagtga caccaaacgc atctgctaaa tgccacaggt tttcgtccgt gattgtttgc
      481 aagattggtc cttgcgcttt gacgtacgta tagacttctg ctgccttttc tgctgtctcg
      541 atcaaaccaa agacttcatc catgtctttt cctgacccgt agattccatg ttgtggccat
      601 aaaaccaatc gagtttcttt cattttttca gctgttgctt ccccaatctc atttgttccc
      661 ggaaccatcc acggaatgat ggaaattcct tctggaaaaa caactaagca ttccgtacac
      721 atttgccata gcgtacgact aaaggaacgt tcgtctaatt catgcgtaaa actcatcgct
      781 aatagatgac tagcatggca atgcataacg atccgattat ctgggtctac ttctaaacgg
      841 gcgatatgac tcatgaaatg acttggcaac tcgcttgtag gaaggcattc gttttccagc
      901 ccccacaaaa gttccagtgt tttgccatct tcagcaactc gaacgattcc aagattctcg
      961 gcaggttcgc tcgctacatt tttaaaatat cttcctgaac cagttacaat aaaatagcat
     1021 cctgctaaac ggctggcatc aaaaatcatc gagatgcggc ggatcacttt ttcaggatcc
     1081 aagaacggtg tgatctcttc ttcttttagt aaataagaaa tattcccgcc atttctttca
     1141 tcccatccca agcgataaag attcgacgtc gtttcgatca tttctttcac ataaggcgct
     1201 tgtaaaatat ctattttttt caatatagcc acactcctat tttcttaatt ccaacacgtc
     1261 tttttgatat tcctggactt cttccagcca atccaaacca actggaactt gatttttgta
     1321 acagaaataa ttccatacat cggcatacgg gaaatctttc aattcttccg tataagccat
     1381 tcttgaagta aagtcaaaag ccagctccat ttctttcaat cgctcaactg gttccagcat
     1441 agctttcagc agtgcttttt gtgtatttct cgtaccgatg acccaagcag cgatacggtt
     1501 gatcgttgca tcaaagaaat ccagaccgat atttgttttt tccaacaatt cgttacggac
     1561 taattcttta gcgatttcct gcaattcatc atccatcaaa accacatggt ctgaatccca
     1621 acgcactgga cgggaaacat gcaacatgat tcctttgctg aataaagcta atgaagataa
     1681 tttattggaa atcacttctg ttggatgaaa atgtccagca tctagacaaa caagtttgtc
     1741 acgagtcaac ccgtaaccca tataaaattc atgggaaccg actgtataag cttcagcgcc
     1801 taaaccaaat agtttgcttt ctactgcatc ttgtacatac cgttcatcta actcttctgt
     1861 aaaaatttca tcgagtgatt ccattaaacg ttcccgtggg gtaaaacgat caatcggatt
     1921 atctttcatc ccatcaggta cccaaaagtt attgatactt gtttgcccag tttctttccc
     1981 aaagtactcc gcgattttgc ggcttctttt cccgtgttcg atccagtatt cacgaacttc
     2041 tttatctgga tgagccaatg taaagccgtc tttcatcatt ggatgcgaaa agaaagtcgg
     2101 attgaagtca agaccgattt cttctttttt tgcccactct acccattttt caaaatgttt
     2161 cggctcaatt tcatttagat cgacagattc ttctgtatcc aaatagatag catgaaggtt
     2221 caatttgtgt ttgcccggta tcaacgaata agccttctcc agatcttgtc taagctcttc
     2281 aggtgttcgt gcggctcctg gaaaattccc tgtcgccatg attccaccgg tcaattcgcc
     2341 atccggtgtc aagaaacctt tgacatcatc tccttgccag caatgcatag aaattttgat
     2401 gtcctgtatc ttttctagta cagcatctgt atctacaccg atagttgcat atttttcttt
     2461 tgcttgttcg taatttcttt caatcgtgtt catacgatta ctcctttgat tttattcacg
     2521 taccattcca tcgtgttttg cttattttca tctgggtaaa aagtttcaca tggaaacgac
     2581 tgtttgatta catttcttgc ttgttctata ttcgaaaact gacctgtact gagcatttgc
     2641 atggcaacat tcccgattgc tgtggcttca ctaggtcctg cttctacaat gattccggca
     2701 taatctgctg tcaattgatt cagtagacga ttattcgatc cgccccctac gatgtgcagc
     2761 ttttccaatt tcgttccagt taagtgttct actttgatca gctcttgtgc gtaacaaaga
     2821 gcaagattat catacacaca acgagcgata gctcccgatg agacagggac tggctgctct
     2881 gtttcaaaac agtattgctg aatctcttct atcatatttg ggggattcaa aaatcgaggg
     2941 tcattgattt ccatcacttg ctgcagcggt ttttcttttg cagcaagctc tgccaattcc
     3001 gcataactgt actcgtactc ttgcattcgg gcaacttcct ggatcaacca catccccatg
     3061 atgtttttca aaaaacgcac cgtgttatgg gcaccccatt cattcgtata attttcagaa
     3121 aaagcattgc gagaaacatt ggcgatcttt gtttcaatcc ctaaaagcga ccatgtccca
     3181 ctgctgatat aaccccaacg ttctccttga cctggcgttc ctaatacagc tgacgccgta
     3241 tcatgacttg ctactgtgat aaaggtcaca tctggcaaat catattttga aaattgttct
     3301 ttttgcagat ctcctagtat cgttcccggc tctgtcaatg gtggaaataa ttccttcgag
     3361 acaccgattt tttcaagaag ttctatttcc cattcttttg tccctgcatt cagcagctgc
     3421 atagtagatg cattagtttt ctccgtcacc atgttaccag taaagacata ccctaaataa
     3481 tcaggtatca gtaacaattt atgtgctttt gccaaatttt ctttttcttc agcaaacaat
     3541 tggaacaagg tattgaaagg ctggatctga atccctgtct gctcatacaa cttatctaga
     3601 gaatagattt cagaaaactg ttctactgct ccattggtac gcttgtcccg ataagcaatc
     3661 ggatcattta tccgatcccc ttgttcatca atcagacagt aatcgactgc ccatgtatcg
     3721 atccccgcaa aaaggcgatc aatccctgtc tgctttaatt tttcaaatcc aatcaaaatc
     3781 tctttgataa gataatcgat cttccagcga tcgtgaccgt ctttgttccg aaagccgttt
     3841 ttgaaacggt gtacttcttc caagatcaaa gaaccttttg catccctcgt acttttcatt
     3901 agtcgtccgc ttgatgcacc gatatcgatg gcaacaaatg ttggattcat ttctccacct
     3961 cttttacttt attgttgatt agcactttat taataaagcg ttatcattta ttaacaatgc
     4021 tatcataata cagaatctta tattttgctt cacactattt tggtatataa ttgcattatc
     4081 ttgacaagtt gggagtgttt acatggatta ctgggaaaaa gccaaccact catggtcgga
     4141 agactcaaaa agagtgatct tgacgcctac acaaagaagc aggaatttat ttttttatat
     4201 ccaagaaatc ggttacttca aagcaccaat cccttactat actgaacgag cacatttacc
     4261 ttcttacttg ataaagttta ctttgtctgg caaaggttcg cttacatata atgataatca
     4321 gcaacagcta aaagctggag acttattttt tattgactgc caagaatatc agcgttatca
     4381 aacgatcagc gaagaaccat gggaaatgga ttggatccat ttgaatggtc agaacgtcca
     4441 atcattttat caggagttca caaaagacgg ccataacacc ttccattcaa caggggatcc
     4501 atcagaaaac aagatccacc atttgatcac agaattgatc cacatgcaac aaggcacgaa
     4561 tgcccgtacc gatttccagt cctctgtagc tatccacgag ttgctgaatg aactgatttt
     4621 gcaaaagtat cagctagatt tcgaagaaga ggatattccc gcctacgttt acaaactgaa
     4681 gcaatactta gacgaacatt tcaaagaaac gattacactt gatcaattag aacaacaatt
     4741 cttattgaat aaatatcagc tgagcaaaga tttttccaaa tttatcggtt ctccaccaat
     4801 cgattatttg atcagcaaaa aactttctta cgctaaagac cttcttcggt atacagaatt
     4861 tacggttcga atgatttccg aagaaatagg gattgagaat tttgcttact ttagccgcct
     4921 gttcaaagca aaaacaggac tatcgccgag agactttcgt aaattcagct gattcatata
     4981 atatgtacgt cattttttca aaatattttg aaatatatag ataaaaataa aataaccgca
     5041 gtttctgctt ctatgtaaac aacagcagct actgcggtta ttttttagtg atcattctca
     5101 ttgttcatct tcaaaatgtt cataatgaac caactgtttc tgtgtatcac gtttcaaaaa
     5161 ttctttaggc gttatgccga actctctctt gaatgctttc agaaaatgcg gataagaaga
     5221 aaaaccactt ttactatata cagcactaga gctgcggtat tctcgcaaca agtgcttggc
     5281 atagatcagc tttttcttca ttacatactg atgaaacgta aatccagtgt actttttaaa
     5341 ttctcgtgtg atatggtatt tgctgacaaa aaactgcttt tccatttcct ctaaagaaag
     5401 cggatgagat aaattttttg agatatattg taacatttgt tccacacgct cattaggaac
     5461 tacagcattc tgttcttgcg cactctcttc tttttgtaca acttgattga gaaaaatcaa
     5521 gtattctacc agagcttgtt catattttat gtcttcaccg taaatttttt tatcaggagg
     5581 atggtcgata aatgataatt tttgcttcaa tacttcctgt tctatttgca atacacgact
     5641 cctcttctct cccattggtt gaaaacaagc cgatagatta gaccatggcg tggaacgact
     5701 ttctagaaaa gaaggggtga caaagatata gacacgctcg aatacatctg aagattggcg
     5761 gacgatacga tgcaaatcat tggaatggat gagcagcaca cttcctgctt tgatcgtaaa
     5821 ttgtcgtccg ttcaaataaa aagtcgcttc tccctttaat gtagcatgga tctcatagaa
     5881 atcatgatga tgatagatcg ttttattttg gctgacgaca tctttgacat gatagatttc
     5941 atactgatca gaaaccatcg tattgacttg ttcaccgctg attttctttt ggagcatgtg
     6001 ccgcacctcc ttttgttcac ttatgcacaa ttttattata ccacgttttt tgtaatcaaa
     6061 aagagctgct tttatatact cttataaaaa agaagagacg tggcatcttc tagccccgcc
     6121 ccctccattc taaatattag ttaaccaacg tcttctttac attattcaag aagacttctt
     6181 ccataacgaa tcccatcatc ttttgtttct tcaagaacca catacaggta cggacgattc
     6241 ttcatgatga tttctttgat ttttgtgtac tcgatcacac cgtctcccaa atttaccggc
     6301 acgatttttt cctgttcgac acgaaaatct ttcaaatgaa ccgcacatat cttttcacca
     6361 aaacgttcaa aagcttcttc taccaattgg acttgttctt gataatcact acttgtgatc
     6421 aaattggtcg gatctaaaat gattcctaga tagtccgaat ctactgcttg gatcagctgc
     6481 tctacccttg ctaaagaata caccggatga ttcaaacctg gttctatccc caccatcatt
     6541 tggtattttt ctccagcttt taccaagcga cggataacgg acacagcttc agcaaatgct
     6601 tcatctgtga aattttcttc cgtatattgg atttccggca aaacacatcc agtttccgaa
     6661 gcaaccatcg acgcaccaaa ggaagaagca tagcgaagat actgctcgaa ctttgtcagc
     6721 aactcttgtc gtatcgttaa atctggatga atcatattga tatagcaact taaaattcct
     6781 acggtcactt cttgcttttc taaaactcgt ttgacataat ttcccatccc agaattgatc
     6841 tcatttgcgc cagaaggtgt ttcaggaaac gaaagaccta aggcgagctg cagtgtatga
     6901 atcccttgtt cttttgtttt ttctgcaaga tcttctatcg tttggacttc ggaaagatca
     6961 tgtcctctaa ttgtaatgtt caacataact attctcctaa ctcagcatat tgggtagcca
     7021 catgacgatt tgcgggaagt aagtaatcaa aaacaagacg actaagataa ccccataaaa
     7081 aggaagaagc ggtttcagca ttgcctctgc ttttacgcct cctacacttg caccgacata
     7141 tagtcctgta cctactggcg gcgtgatgga gcctacacac agattcatga ttgaaaacaa
     7201 cccgtaatgt acaggatcaa cccctacact tgtgacgatt ggtaaaaata ttggtgtaaa
     7261 aatcaagata gcaggcgcca catccataaa catacccacc agtaataaca caagattgac
     7321 taataacaga ataataaatt tattatccgt tacgcccata atcaacgaac taattgcctg
     7381 aggaataccg gtaaacgcca tggcgaaaga catcatggaa gaagtagcca ataagaacat
     7441 gatcgtccct gacattgcta ctgattgaaa caacatatta ggtatatctt ttagttttac
     7501 cgttttatag taaaacatag caatcaacag ggagtaaatg acagctatcg ctgaagcttc
     7561 tactgctgta aatatccccg tcaagatacc accgataatg atgacaatca atagaaggct
     7621 aggaatcgcc tcttttatta tttttccagc atgagccatc tgtccttttt cgacaacagg
     7681 gtatttattc tttttagcaa cgatgaatgc tactagcatg attcctagcg cccacaaagc
     7741 gcctacgaga taacctccca taaacaaagc agagatcgaa gcaccaccag caacaagtga
     7801 atacatgata aaagcagtac ttggaggaat gaccatacct gtcggagctg acgcgatatt
     7861 gaccgctgtc gcaaacttcc ggtcatatcc ttcttccact tgctgaggga tcaacactcc
     7921 gccaatcgcg gtagaagcgg caatggccga gctagagatg gaaccaaata aagcattccc
     7981 taacacattc gtatgagcca aagcccccgg cacgcgcccg acgaacaaca tcgcaaaatc
     8041 cactagtttc ttagctatcc ctccattatt catgataatg cccgagagaa cgaaaaacgg
     8101 aatagcgatc agcgaaaaac tattgatact tcccaccatt ttttgagctg aactaaaagc
     8161 agaaacatca aacggtataa ctaacaataa agtcatcatc gatgagaatg caatacttat
     8221 agcaatcggc atccctaata caagcaacac aacaaataca aaaaataaca ctaatccggc
     8281 ttctattgcc attttattcc tccattttta tattttttct tgaattgctg gcttgttgct
     8341 taatgtatcg attagattga tcaggctata gataatgatg agtacccccg atacaggtac
     8401 tgacagataa acatatccca taggaatact taaagaaggc gagatctgcc ccattgtcaa
     8461 tgtgacagca ttccatccgc catacaccat gatcatcgca gcaaatacca gaaataaact
     8521 ttgaacaaca acttctaaaa ttttactttt tttgccagtt aatttttcac ttaaaaccgt
     8581 tacggctaaa tgtgcttttt gtcccacaac atacgcggaa gacaacatgg caaaccagac
     8641 aagaccgaat cgaacaagct cttccgtgac cgtatttgga tttcctaaaa ccgttctgga
     8701 aaatacttgc cataaaacaa cagcgaccat cccaacaagc aaaacagctc ccaggatctc
     8761 taataccttg tttaaaatca ttttcatcac agctacgctc cttgctcttg gatcttttga
     8821 taaaggtctt tgtaggtagg atcgtttttg aatatatcat gaagtggggc aactgcctct
     8881 cgaaacggtg tattatctac atcattgaat tggactccat gttcttcttg tgctaaagct
     8941 ttttcttctt caattgcttt tgcaaaagct tcaatttcaa aaaccgttga ttctttcgct
     9001 gcttcttcaa tggctttttc ctgctcatca gttagctgtt ctttgatggc atcattcatg
     9061 atgatgatat ctggcacacg tgtatgctca tcataggaat agtatttagc cacaccacca
     9121 tgtccagctg tatacaagac aaattcattg ttttctgatc cgttgatcaa attggattga
     9181 agagacgtgt acacttcatc acttcccata ggtacgggcg aaccgcctaa aagctctacc
     9241 attttgatag cggtttcgct ttgcatcaca cggatcttct ttccctccaa atcttccggc
     9301 gtatggatcg gaccgtctac catataaaag ctgcgctgac cagaatcata ataggtcaat
     9361 ccggtaaatc ctaaattttt ggtcgattgg tagattggct ccattatttc ttcattatcc
     9421 atcaccttaa agaaatgttc ttcatcattg aatagataag gaactgaaaa aatcgaataa
     9481 tctttagaga aactttccaa cgctgaggca cttacttttg tgaaatctac tgctcctgac
     9541 tgtgtcaatt cgatcagttc acgttctcca cccagttgtc catctgggaa atactggatc
     9601 tgtacggaac catctgtttt ttcttttact aaacgcccaa attcattcat tgcatcaatt
     9661 actggctggc tgttgcttgc ataagcaaag cgcaaggtaa ctatctcatt tacatctgca
     9721 tctgcgacag ttgccacact agaattattt ccgcagccgc ttagacctag cagacctagg
     9781 ctaagcgaac ttgctgcaaa cagcagtgat gtttttttca tatgggtttc ctttctttta
     9841 acaataagag acgagcaatt ctgtcaaaca aagcaccgtt aacgactgtc cataaggcat
     9901 tgctgtgatt ccgatattcc gataaaaatc taaactgtcc cccattcctg tcccgattga
     9961 aacgttttga acttctcctt tttcatcgat ttgttcaagc aatccttgga tagcacgata
    10021 agcgacttct ttatattctt gtggtaaata acgtttatgg accgctttca aaataccgta
    10081 agcaaatcct gcagttgcag aagattctac gtaagaagaa ggatcatcca acaacgtatg
    10141 ccataaaccg ctttcagact gataagtttt taatgcacgc acttgtgctt caagtgtttc
    10201 gatcaataat ttgcgcaatg catcttcttt cgataattct aagatttcaa tgatctctgg
    10261 aatagcaatc gtcaaccagc agtttccacg agcccaaaat gcttcggcat agttatgatt
    10321 tccttcaaac gtccagccgt gataccacaa tcctgttcgt ttatccatca agtatttgat
    10381 atggatcata aactggtaac gagcttcttc taaatattct gggcgattca acagtttccc
    10441 gatttttgcc aaaggaagca ctgtcatcat caatgtatcg tcccacaact gattcttatt
    10501 ttccggtcca tatgtggcat gctgtaaccc gtcttcattt gtccgaggca tgtcattcat
    10561 gacccattct gcccattgtt ctaaataagg caaatagcgt gaatctttcg tgtcttcata
    10621 caagtaagcc atagtcaata gcggtgccat tgtattgacg tttttgggcg gagcgccttc
    10681 ttccatacga tcctcaaacc attcattgac cacttgataa gcgcgaggat tttttgtcat
    10741 ctggtaattt ttataaatac catatagacc gacaccttgt ggccaattcc acactgtcca
    10801 gcttttgtca tctactttca gtccatcaaa gtccaacaaa aattcaccat tatcgtcttt
    10861 gatcgttgtc aggttttcaa cgagcaggtc aattttttct ttcactaatt ctttaggtac
    10921 aaaaatctct tctttaataa tcatctttac gccacctttt taaacgcttt cattttatat
    10981 ccttaatata gcagtaatac cgtccactat aaatatcgct ttttgaacaa aaactgtcta
    11041 aaattgacct aaatgttaaa taacaaaagt aactttcagt tacttggaaa ttaaaaaaag
    11101 aacttggaga aacaacgttt tccaagttct ttttcatcta ttttcttatc ttttttctac
    11161 gctttctttt gcttatccgt tgtaagcatc aatgatgatc tgtttcaatt cagagatcaa
    11221 tggttctttc ggattagctg tcgtacattg gtcttcgtaa gctaattcag ccatacggtc
    11281 tacggttgta tctagtgttt cttgtgtgac tccttgagct tttagactca tgttgatgcc
    11341 gacagatttt cctaattcat aaacagccgt tgctaaagct tcgactaatt cctctgttgt
    11401 ttcgcctttc agacctaaga attttgcgat atctgcgtaa tctgtatctg cacggaaata
    11461 gtcatattta gggaacatcg catgtttttg tggatctttt gcattatagc ggataatatg
    11521 cggtaaaaga atcgcatttg tccgtccatg agggatcccg tattccccgc cgattttatg
    11581 tgcgactgag tgacaaatac ctaggaatgc gttagcaaac gccataccag ccattgtaga
    11641 agcgttgtgc attttttcac gtgattccat atcaggtgtt tttactgatt tttctaaata
    11701 gtcaaagact aacttgattg cttgtaggct caatccacgt gtataatctg aagccatgac
    11761 tgaaacatag gattcgattg catgtgttaa cacatccatc ccggtatctg ctgtgacaga
    11821 tgctggaact gacatgacga attgaggatc gacgattgcg acatctggcg tcaatgcata
    11881 atctgctaac ggatatttca catgtgtttc actgtcagtg atgaccgcaa atggcgttac
    11941 ttcagaacca gtccctgatg ttgtcgggat acatacgaat tgtgtttttt ctggtttgtc
    12001 gatcttatat gtccgtttac ggatatccaa gaatttttgt tttgcaccaa agaaagatgt
    12061 gtctgggtgt tcatagaaca tccacattcc cttagctgcg tccattgcag aaccgcctcc
    12121 aagagcgatt actgtatctg gcttgaagtc tgccatcagt ttcgttcctg cgtatacggt
    12181 atttgtcgat gggttcggtt caacatctga gaagacttcg atcttcacat catttttacg
    12241 tcgtgccaat acttcacgaa ctgtatcgca gtaaccgaat tggaccatac cagggtcaca
    12301 aacgatcatg acacgttcaa cgttttccat tttctctaag tacaatagag agttcttttc
    12361 aaagaagatt tttggcggta atttgaacca ttgcatgtta tttctccgtt tcgctacagt
    12421 tttgacattg attaagttta cagcagagac gttacgagaa acagagttct taccataaga
    12481 accgcatccc aaagtcaatg acggaatcat ttcgttatag atatcaccga tgccgccttc
    12541 tgcagatggt gtattcacta aaatacgaca agctttcatt cgaagaccga atttgacatg
    12601 caactcttcg ttttctgaat ggataactgc tgtatgtcct aatcctccaa gattcaacat
    12661 accttcacac aaatcaaacg catggtccgt gttgttagct ttgatcatgg caagaactgg
    12721 agaaagtttt tctcttgata gcggataatc tgggcctacg ccttccaatt cagcaatcag
    12781 cattttcgtt ccttttggta cactgattcc tgccaatttt gcgatttcca tcgcagaatg
    12841 tccaacgatt gatggattga ccgcatattt tccttcgttc atcactgcat cttctaattt
    12901 ttgcaattca tctggtttta cgatataaac ttggtgtgct tggaattctg cttttactgc
    12961 tgcatagatt tctttatcca cgatcacagc ttgttcagaa gcacaaatca ttccattatc
    13021 aaatgttttc gaaacgatca aatcgttcac tgcacgttta atttttgctg ttttttcaat
    13081 ataagctggt acgttacctg gacctacacc taaagctggt tttcctgtag agtaagcaga
    13141 cttgaccatt ccagctccac ctgtcgctaa gacgatcgcg atacctggat ggttcattag
    13201 catagaagtc gcttcgatcg aaggatgttc gatccattgg atacaatttt caggagctcc
    13261 ggcagcgata gcagcatcac gtaccactcg tgctgcttct gcagaagatt tttgggcact
    13321 tggatggaaa gcaaaaacga ttggatttct tgttttcaac gcgatcattg atttgaaaat
    13381 cgttgtggaa gtcggattcg ttgttggagt tactccgcaa accacaccga ctggttcagc
    13441 aatttcaatc aacccttttt ggacatcttc attgatcaca ccaactgttt tatcatgttt
    13501 gatattatgc caaatatatt cggacgcata catatttttg attgctttat cttcgtaaac
    13561 accgcggcct gtttcctcta cagccatctt cgctaatggc atatgttgat ccaaagctgc
    13621 cattgccatt tcatgcacga tatggtctac tttttcttga tcaaagcttt ccatttcttt
    13681 caatgctgca tttgcttttt ctgccaaatc atcaatcatt gcttgtacgt caattgtctt
    13741 cgttttttct ttttctatta ctttagccat cattatcctc ctaatgggtc atggttattt
    13801 gttaaataat tcacatgtat atcatacaat atttattttt ctatgtaaac acttttttgt
    13861 gatttttttc acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga
    13921 aaaatatata aagttattta ttattattta tatgacacac ccgattattc aatattgagc
    13981 aatatatccc atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt
    14041 ctgccctacc tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct
    14101 cttccagcgt ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg
    14161 tttcaacagt agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg
    14221 ctgcacgatc gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat
    14281 tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt
    14341 tcatgctatc taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa
    14401 aaaaccacat tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt
    14461 tcacctcact aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta
    14521 gttttttact taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga
    14581 acccgtattc ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt
    14641 gacgtacttg tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa
    14701 tcccaaatgt ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac
    14761 atgtataaca atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt
    14821 tcactactag acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca
    14881 agacacagtc aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac
    14941 cgacacccat caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata
    15001 cacgattcat ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga
    15061 aatccatccc gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt
    15121 ggatgattcc aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg
    15181 cccatcgaga cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg
    15241 gacattcgtc aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt
    15301 tttctggtga taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt
    15361 cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa
    15421 tcggttgatc ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac
    15481 cagggcgtag ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca
    15541 actcttctgg ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg
    15601 tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt
    15661 tcttgattaa acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa
    15721 aatatcttga caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg
    15781 cttccttcta ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa
    15841 agaaaaacat tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa
    15901 aggagggaaa aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa
    15961 aaggacgttg gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta
    16021 ctattcttct tattatgatt cctattatct tgtttgccac caccatatat gatggatcag
    16081 cgagcgtctc agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta
    16141 tttccagcat cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt
    16201 tacgtggaca aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt
    16261 tgtttatcgg cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg
    16321 gtttgctatt agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta
    16381 tttactacga tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg
    16441 caagtcgaaa attgatggat ggttataaag gacaactttt ctggttagat ctttcattta
    16501 tcggctggca tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat
    16561 acatttctgc aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag
    16621 tgtgacttgt gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa
    16681 acattcagcc cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt
    16741 atagttccag taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt
    16801 ccggtaatcg atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc
    16861 ctaccaagaa ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg
    16921 gcagcaaagc aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt
    16981 tattggtcgc taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca
    17041 gaatcgatga ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt
    17101 ctacccatgg gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga
    17161 tggtgaagac ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt
    17221 catttttcgg aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag
    17281 caaatcctgg aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg
    17341 gtgctcccca tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc
    17401 ttagcaaaaa gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag
    17461 cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca
    17521 catctgttcc tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat
    17581 cattcacacc atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga
    17641 tccggatctt gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat
    17701 ctaattcttc gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat
    17761 tcaagatacc taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca
    17821 tgactgtttt gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg
    17881 gtggatcgat cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag
    17941 aaatatcttg cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc
    18001 gtttaccaaa gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg
    18061 gagcaagaac atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa
    18121 ctgttgtcat catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt
    18181 cttctaattc tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg
    18241 ttggattacc tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata
    18301 gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta
    18361 cttcatcttc tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg
    18421 ttttgtctga gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga
    18481 tgatcgcatg tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa
    18541 cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa
    18601 ggagtggttc tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga
    18661 tcatactgat tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag
    18721 tattttcgtt caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga
    18781 cgatcgcttt cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt
    18841 cacctaatga ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt
    18901 ctccagtcaa cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg
    18961 cagaaatagc atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact
    19021 caacagtggt cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca
    19081 aggattccag tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca
    19141 caacgatagc gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg
    19201 tataaaagga aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc
    19261 gaaagaattt tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct
    19321 tttttcgccg ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta
    19381 ccttctttac ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc
    19441 ttcgtacaaa aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa
    19501 agggcttatc gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg
    19561 ctaccaaagg atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag
    19621 aatttctcga tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga
    19681 catgcgtgta gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag
    19741 tatccgaaac aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt
    19801 gaataggaac aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta
    19861 acatgaagaa attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt
    19921 ttatttgaat ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt
    19981 tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt
    20041 atttcacgaa catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct
    20101 ggtaagcaga taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg
    20161 attttggcaa atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg
    20221 taatgaaaat atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa
    20281 tcgtttctaa tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac
    20341 gtacttggtt caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat
    20401 ggtgttcttc aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg
    20461 tcagatagac taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat
    20521 gcaatccagc tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc
    20581 gatctgggtc ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt
    20641 caagaatctc tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca
    20701 attcttcttt cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt
    20761 tggcacgttt cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa
    20821 gaaggacttc taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa
    20881 ctcgtgtatt attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga
    20941 aatgtttatc ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc
    21001 ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg
    21061 ttgttaacat atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg
    21121 ttctgttggc aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac
    21181 taccctattt gtattttttc attgttttag gcatactagt aatagatagt tcttcattga
    21241 aaatagaaaa agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg
    21301 tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt
    21361 tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga
    21421 tccaacacaa gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga
    21481 attgcgacgt cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat
    21541 ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa
    21601 aacagctgaa aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc
    21661 acatgaatta tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa
    21721 tcaagatatc atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc
    21781 cttgcaagac cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac
    21841 ccatgacatg gatgaagc
//
LOCUS       DAKCAA010000046        20819 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000046 DAKCAA010000000
VERSION     DAKCAA010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.046"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(4..840)
                     /locus_tag="OUE31_001887"
     CDS             complement(4..840)
                     /locus_tag="OUE31_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCU0222879.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(837..1706)
                     /locus_tag="OUE31_001888"
     CDS             complement(837..1706)
                     /locus_tag="OUE31_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCU0222880.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(1776..3059)
                     /locus_tag="OUE31_001889"
     CDS             complement(1776..3059)
                     /locus_tag="OUE31_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCU0222881.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(3073..4758)
                     /locus_tag="OUE31_001890"
     CDS             complement(3073..4758)
                     /locus_tag="OUE31_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HCU0222882.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            5033..6058
                     /locus_tag="OUE31_001891"
     CDS             5033..6058
                     /locus_tag="OUE31_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0222883.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(6653..10327)
                     /gene="rpoC"
                     /locus_tag="OUE31_001892"
     CDS             complement(6653..10327)
                     /gene="rpoC"
                     /locus_tag="OUE31_001892"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HCU0222884.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(10385..14002)
                     /gene="rpoB"
                     /locus_tag="OUE31_001893"
     CDS             complement(10385..14002)
                     /gene="rpoB"
                     /locus_tag="OUE31_001893"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCU0222885.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFVDQTNPLGELTYKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            14730..15698
                     /locus_tag="OUE31_001894"
     CDS             14730..15698
                     /locus_tag="OUE31_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCU0222886.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            15716..16621
                     /locus_tag="OUE31_001895"
     CDS             15716..16621
                     /locus_tag="OUE31_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0222887.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            16618..17424
                     /locus_tag="OUE31_001896"
     CDS             16618..17424
                     /locus_tag="OUE31_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0222888.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            17560..18549
                     /locus_tag="OUE31_001897"
     CDS             17560..18549
                     /locus_tag="OUE31_001897"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HCU0222889.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(18866..19390)
                     /locus_tag="OUE31_001898"
     CDS             complement(18866..19390)
                     /locus_tag="OUE31_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HCU0222890.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            19677..>20819
                     /gene="scm"
                     /locus_tag="OUE31_001899"
     CDS             19677..>20819
                     /gene="scm"
                     /locus_tag="OUE31_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HCU0222891.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTD"
BASE COUNT         6085 a         4406 c         3925 g         6403 t
ORIGIN      
        1 tttttatcct tttacgccgc cttcgactaa atcaccttta ataaatcgtt cagataacgc
       61 atacataatg atgactggta aagcggtcac caatgaagcg gccatcattc gtccccaaat
      121 gtagtctggt gtactgaata atgtgttcaa accgattggt aaagtaaatt tttcggaggt
      181 cgacaggaaa atcgaagcaa ataaataatc attccacgaa accataaagc aataaacgaa
      241 gacagaaatg attccagaaa tagccaatgg tataatgatc cgaataatga tctggatccg
      301 gctaagacca tcgatcattg ctgcttcttc aatatcagtc ggaatcgtgt caaaataact
      361 ttttagcatg aatatcgcag taggaagtgt ttgaacgacc atcgtgataa tcagtgctgt
      421 attggtatca tacaaaccta gaccggaaat gattttaaat aatggaacaa cgatcaaaat
      481 accggaaaac atataaacgg tgtaaaagct agcattgatt ttcgagcgag ctttgaagcg
      541 tagttttgac aaagcgtatg ccccgctgat cccaatcact actgcagtta cggaggctat
      601 caaggagatc actaaactat ttttgaaata catgatgaat ggaaaaatct cagcattgaa
      661 aatatcctga taatgttcaa aagtccattc tttcggaaaa atagtttgtg tcgttgcaat
      721 tgcttcttgt gaatccttga atgatgtcat cagcatgatc aaaaatggaa acaaattgac
      781 agctaatagc aacaaaatcg tcgcgtaaaa taagattttc ctgctctttt tatttttcat
      841 ttcaagtcca ccttctttcg tgagagcaag acgaccgctg caataatgat gaacaataga
      901 atcgatatag ctgctgcttt tccaagatca ttgaacgcaa aggctgtctg atacaaataa
      961 acgcctaaga tattgacttt attcgtcagt agatagacat ctgtaaacat atagaacatc
     1021 cagatagatc gtaaaacaat cacagttgct agtactggtt tgattgccgg cagtgtcacg
     1081 atcttgaact tctgccaagc atttgcaccg tccatttcag ctgcttcata aagcgttttg
     1141 tcgactgttt gcaaaatagc caaaaatgaa ataaacgcat acggatagta tctccagata
     1201 gcaaacaaaa cgaccataaa gaagctagca actggctggt cgaaccacag cggtgcttcg
     1261 ttgaaaagct gcaacctatc tactaacaga tcattgacga ttccataact attattgaac
     1321 atatatttcc aagcaaaaat caaagaaata gatggcgtaa cataacttaa taaaatcagt
     1381 gaacgcaccg ttttcctaaa tctgaacttg cggttaagca aaatagctac ggctaatcct
     1441 aaagctgtac tgcctgctac aactaagaat gtgtaagcaa ctgttaaacc taaagaacga
     1501 taaaattcac tatcacttaa aatttcaaga taattgctta atccgataaa aacggcgtct
     1561 gagttaggat tcagcggcat atcgaaaaaa ctgatctgaa tattggaaag cattggaatc
     1621 agcactaaaa cagctaataa aagcatgctt ggtgctaaaa gtcccatggc taattttaag
     1681 tcagaatgtt tccttggacg attcattgaa acctccccct gataatctgc caatagctat
     1741 ctactttttt cgaacaccat tggcagaact tcttgttatt tcgtattttt ttgtgcgtca
     1801 gctaaagctt gatcgacatc ttcgtttccg acagttactt ggttcactgc ttttccgatc
     1861 acacctgagc ttgtgatatc tcccattttc gtgaaattct tttccccgac tagtccaaag
     1921 acttgtactt catcaaaagc actagcaatc tcagatggca gctcgccaaa agacttgatg
     1981 acttcatttt ctttgtaacc atccagttcg actacttgtt tattcactgg ttgagcacca
     2041 ccaggagaca tcaagaccca cttttccatg tttttcggtt gagataagaa agctgtgaat
     2101 gcttcagcag cctctttttg tttctcgtct agaccagaag aaatcgtcaa tccagatact
     2161 gtgccataga cagcttgatc tttttgtgtt gggatagcaa aaccgatatt ttctgagttc
     2221 cccgcttcat aaacagaagg caaaatgtaa gttgaataga ttgccattgg tgctgttcca
     2281 ttcatgaaag catctttgat ttctgtcaca tcattagagc ctggcatcgt gtattgggat
     2341 aagttttgat aaaacgacaa tgcttctctc atcttttccg tatcgatcgt tacctcgcct
     2401 tcatcatcca aaacatttgc tccatttgac aaagcaaatt gagagaacgc ttgctcactc
     2461 attgttcctt cagcagtagg catagcaatt ccatattgtt tattctcttt atctgtgaaa
     2521 tgttgagcaa tttttaaaat atcatcccaa ttttctggtt ctgaaaaacc agcttctgat
     2581 aatttttctt tgtcatacca aataccttga acccagccgc taattggtgc agcaatatag
     2641 ctttttccat cttctgaacg aacaaggttt ttggctccgt cataataatt atcttctcca
     2701 gcttcctcga taacgttttg gactgccgtc tgatcaatca gttcatcttt atccatcact
     2761 ttagcaaaat cctgactgac ttccattact tctggtaatt taccggaacg agctaacgta
     2821 acgatttttg tattgaacgc tgattcttct accggcactt gcttgatttt gatgtctgga
     2881 ttttcttttt caaaatcagc aaccagttca ttgatcacac ttaatcgttc ctgttcgaca
     2941 gaagagtgca tgaattgaat cgttgtctgt tgtgattcgt tagagctttg actttcacca
     3001 caagcagtaa gaagaaatcc agtagctagc agacaggtag taacaataat ttttttcatt
     3061 tttttccacc tcttatttta ttattttcag ccacatatat tcatacggct ggaatatcaa
     3121 ctttcgttct tgactgcaat ggataatttg tccagaaaac aggtctaggt aatctccttt
     3181 tggtaaaaga taacctgctg attgattgga aaaattatgg ataactaaga ctttctcttc
     3241 cttcgcttcg cgaataaaac tgataaaaga atctgctgag tccagtaagt aaatcaaact
     3301 attcggatgg aaggcttttt ctttttttcg aatagatagc atctgggtca attcaccata
     3361 tactgctgtt cttaatggat ctgtctgcaa ctctttctca atatctgcta acaaaaattt
     3421 ttgccgattg atttttcgat tctctcctgt tttttctacg cctttgtaat catttcgact
     3481 tcccagcaca ctttgaatat aaattgccgg cacgcctggt aacgttacca aaaatgaatg
     3541 agcagctaaa aagcgtttgc ttctccattc cgtcgtatct gttggagaac ttaacgcatc
     3601 tagatacgta gcgtttatct catatggact ggtcgttcca tctgggtttt tcttgtagtt
     3661 tactcgggca ccctctttct tcagctgttc cactaattca aggatcgttt tttccggcag
     3721 aatacctcgt accggattca atccgatacc gtcatgggag gctaaaaaat taaaaaaagt
     3781 tgtttttttc gatgcgaaat cgatggtttt taaccattct ttcaacttac ttgtattacc
     3841 cgaacgaatc gcttgaaggg tcaaaggtgg tagcgaaaac tgatagacca tctgtgcttc
     3901 attctcgcca ttcccaaaat aactgatatt atctttgtgt ggcacatttg tctcagtgat
     3961 caataccgtt cctggagctg cttcatcagc gattgcacgg aataattgga tgattttatg
     4021 cgtttctggc aggtgtatac aagaagttcc tagttctttc cataaaaatc ccacagcgtc
     4081 caagcgaata aatgaagcgc ctttttctaa gtaaaacaaa agaatatcga tcattttcaa
     4141 taaaacttct ggatttttaa aattcaagtc tacttgatct tcgctaaaag tcgtccatac
     4201 gtgtttttct ttcccgtttt tgtcaatgaa cgttgtaagt aacgggctgg tccttggtct
     4261 agtcacgctg cttgtatctg tatccagtgg caaatcaata aaaaaatctt tgtacgtatc
     4321 attcaagttt aaatattcct gaaaccaagt actttcggca gacatatgat tgcagacaaa
     4381 gtcgaacatt aaccgtgttt cgcttctcat ttcttctata tcttcccatg tgcccaaacg
     4441 gtcgttgatt gcctgataat ttacaacgga gaaaccatca tcagatgtat atgggaaaaa
     4501 tggcaagaaa tgtacaactc taaatgtatc tgccaaatac ttttgataaa atttcttaaa
     4561 tgtacgcaaa gttggttgct gctcttcaaa aaattgatcc ccataagtaa tcaagaaaat
     4621 atcttcttcg tcccaatgca gtttgcctgc ctggcctttc ttctgctgat aaacactgac
     4681 tttttgttca atcatagagg cggttttctc agacaaatct gagtcgcgat aaatcgcttg
     4741 taaaagtttt gtatacatcg gattcccctt tcttttttgg gagcgttccc aacgatttga
     4801 tcatattatg gaaaacgctt actgtcaata gcattttttt aaataatttt gatatacaca
     4861 aaaatacaaa taagaaagct tatgtatcaa taattaatag cttcttaaaa aaatatggtc
     4921 tctcatgatc atgcaagcta ttcctaaatt ttcaaaatca tagacaaaaa agaatgtcta
     4981 ttgtactatg gaattattct aaaacgctcc caaaaaggag gtgcatataa aattgaaacc
     5041 tactatttat gacattgcga aaaaagctaa tgtctcaaaa tcaactgtct ccagagtatt
     5101 aaataaccag ccaaatatct ctgataaagc aaaagcaagt gtacttcaag caatcaaaga
     5161 attgaattat gaaccgagca aaattgcaag aggactgtca ggaaatggtt ttgacgcgat
     5221 tctagcatta tctcatcgta cttctcatac gacctatggc aatccttttt tttcagatgt
     5281 tattcaatcc atttctgccg tttctgaaca aaataacttc gacttgattc tacaaacggc
     5341 aaaaacacca gaagaagagc tagaaaaatg cgcgaaaaag atccaagaaa aaatgatccg
     5401 aggaattatt attttaagct ctacgatgga tgaaacactt ctttttgaat tggatcaata
     5461 caatattcct attgtggtaa tcggaaaagt cggaaacgac tacacgaaca tctactcagt
     5521 ggacacggat aatttccagg atagttacga tttggtggaa acactgatca agaatggaca
     5581 ccgtcatatc ggctgtctcc atgctccgac agaagtttat gtatccaatg atcgtctcaa
     5641 tggttaccgt caatgcttat ttgatcacca cctagatatc cgtaatgaat ggattataga
     5701 cggcggcttt cgcttagaag atagcatggc agcaatgaat gatttaatga agctacgaga
     5761 aagaccaact gcgatttttt ctaccgatgc attaaaatca ttgagtattt acaaagtggc
     5821 agaacaatct ggaaagcaga tacctgatga tctttcgatc gcaggattca gtgatccctt
     5881 attgtcctcc ctattttcgc cacagttgac tcggatagac attccgacaa atcagttagg
     5941 aatcaaagcc acagaacttt tattccaact aatccaccac caataccctg aagaaaaaag
     6001 aatcattctt tcaaccgaga ttactctcac agattcgatc caacaacaag aaatgtagaa
     6061 cagaattata aaagaacaga aacactgagg ataagtcagt tactctgttc ttttttcaat
     6121 cactcatccc tcgttacccc ctcccggtat tttagcgaat ttttcttatt ttccatctgt
     6181 tttagatagc tgtggataac tataatgttt gtgttaaact attttttcca cagggaagaa
     6241 aaaactattt ttaaccacgt tgtgtataag tttttatagt tcgttttttt aaacacattt
     6301 acccttattt caatccatgt tatttgggga tacttatctc taaaacataa atagaataac
     6361 agacatgtct actggttttg ttttattcga ggaattattc aataatagct agcaaaatat
     6421 taaaaataac cgctctatct tcccatcaat ttattttgca ttcaaaaaat gatctatctt
     6481 tacttttgtt gattgacttc tcttggaaga tgatcgttcc gataccttaa ttggatacga
     6541 accgatgttg ttaagatcct ttcccacttt tcttctagtt agacaaatta ttttagacaa
     6601 accaaaaaag aggttgtgac aataatttgt cacaacctct tttttaaaat atctattttg
     6661 tttgattgtt cattgcgtct tctgcagcca tttgcgcttc aatatctgaa atactgtaga
     6721 cattttcgct tgctacaccg acttcttttg gttccatgtc acgataacgt tgcataccag
     6781 taccagctgg gatgatctta cctataataa cattttcttt caaaccaaga agaggatctt
     6841 tcttaccgcg gatcgcagca tccgtcaaga cacgagttgt ttcttggaat gatgcagcag
     6901 ataagaaact atttgtttct aatgatgctt ttgtgatacc tagtaagaca ggtcgagaag
     6961 ttgcaggaac gcctcctgag actagcgtat tgtagttttg atctttaaag tctgcgatgt
     7021 ctaataatgt acctggtaag atatctgtat cacctggatc cattacacga actttacgca
     7081 gcatttgacg aaccattact tcgatatgct tgtcgccgat ttctacccct tgcatacggt
     7141 aaacacgttg tacttcacga agcaagtagt tttcaacaga taatacatcg cgaacttgca
     7201 acaattgttt tggatcgatt gatccttctg tcaatggtgc accacggtgg atcatatcgc
     7261 cttctgctac tttcatacgt gctgtataag gaacagtata cgtacgtgta tctgtttttc
     7321 ctttgattgt tacttctttg gtacgtgttg caggatcttc tgagatatcg atgacatccc
     7381 ctgttacttc tgtgatcact gcttgccctt tcggattacg tgcttcaaag atttcttgga
     7441 cacgaggaag accttgagtg atatcgtctc cggcaacccc acctgtatgg aatgtacgca
     7501 tcgtcaactg agtaccaggt tcaccgattg attgagcggc gatcgtacca actgcttctc
     7561 cgacttcaac gtcagagcca gttgcaaggt tgcgtccgta acaatgtttg cagacaccat
     7621 gttttgtatt acatgtgaag acagaacgga ttgtcactgt ttcgacacct gcatcaacga
     7681 tttgttttgc gatgtcttcg gaaatcaatt ggtttcctgc aatgatcaat tcatttgttt
     7741 caggatgacg tacttcttta cgggtgtaac gtcccactaa acgatcttct aatgattcga
     7801 tgatttcatt tccctcgcgg atggcttgga tttcaagacc tcggtcagta ccgcaatctt
     7861 cttcacggat gattacatct tgggccacgt caaccagacg acgagtcaag taacctgaat
     7921 cggcagtctt caaggctgta tcggtcatcc ctttacgagc cccgtgagtt gagataaaca
     7981 tttccaagac ggatagtcct tcacggaagt tcgaaatgat tggcaattcc atgattcgac
     8041 cattaggagc ggccatcaaa ccacgcattc cggcaagctg tgtaaagttg gaaatgttac
     8101 cacgagctcc agaatcagac atcatgaaga ttggattttt cgcttccaaa ccttccatca
     8161 gtttttgttg gatgctgtct tttgcagcat tccaaacagc aatgacacgt tcataacgtt
     8221 cgtcatctgt gatcagacca cgacggaatt gttttgtaat agtttcaact tgtttatggg
     8281 cattttcaat gatttcttgt ttttcattca gtacactgat gtcagcgatc cctactgtga
     8341 taccggcatg tgtcgaatgt ttgtacccta agtctttcat acggtcaagc atcttagaag
     8401 tttctgttac tttgaatcgt ttgaagactt ctgcgatgat gtttcctaag tttttcttct
     8461 tgaacggtaa tactaattct tgctctttga tatgtgcagg aatatcagta ccagcttcaa
     8521 caaagtattt gtccggtgtt tggacggtca agttgaagtc tgttggttca ttcagataag
     8581 ggaattcagg aggcatgatc tcgttgaaga tgatcttacc aactgttgtg atcatcgtac
     8641 gttctttttg ccattcagta aatggttttt cacctaatga gttagggttc acaccgatac
     8701 gtgaatgtaa atgaacatat ccgttgcgcc atgcgataac ggcttcgttt tgatctctga
     8761 agaccattcc ttcgccttcg cgtccttctt cttccattgt caagtagtag ttacctagaa
     8821 ccatatcttg agaaggagta acaactggtt taccatcttt agggttcaag atgttttgag
     8881 cagctaacat caacatacgt gcttctgctt gtgcttcttc attcaatgga acgtggacag
     8941 ccatttggtc tccatcgaaa tcggcattat aagcttcaca tacaagtgga tgcaaacgga
     9001 ttgcgcgtcc ttgtactaaa actggttcga atgcttggat accaagtcgg tgaagcgtag
     9061 gtgcccggtt cagcaatact gggtgttcct tgattacgtc ttctaaaaca tcccatactt
     9121 cgtcttcttg acgttcgatt ttacgtttcg catttttgat gtttgaagct agttcgcgtt
     9181 gaacaagctc acgcatcacg aatggtttga ataattcaat ggccatttct tttggaagtc
     9241 cacattggta catcttcaag aaaggtccaa caacgataac ggaacgacct gagtagtcga
     9301 cacgtttacc tagcaagttt tgacggaaac gaccttgttt ccctttcaac atatgagaaa
     9361 gagatttcaa tgggcggtta cctggtccag taactggacg tccgcgacga ccgttatcga
     9421 tcaatgcatc tactgcttct tgcagcatac gtttttcatt ttgaacgatg attccaggtg
     9481 cattcaagtc taacaaacgt ttcaaacggt tattacggtt gattacacga cggtaaagat
     9541 cattcaagtc acttgttgca aaacgtccac cttctaattg aaccattggg cgtaaatctg
     9601 gtggaataac agggataacg tccataacca tccagcttgg ttgatttcct gaagcgcgga
     9661 atgcttctaa aatatccaaa cggcggattg cacgtgtacg tttttgtcct tgtgcagatt
     9721 tcaattcttc tttcaattcg gctgcttctg catctagatc aacattatca agtaattgtt
     9781 taatcgcttc tgcacccata gcagcttgga attcttgtcc atattgttca cgtttttcgc
     9841 gatattcgcg ttctgtcaac aattgttttt tctctaaatt cgtatttcct ggttcgatga
     9901 ctacatatga agcaaaataa atgatttctt ccaaagcgcg tgggctcatg tctaatacaa
     9961 gacccatacg tgaaggaatc cctttaaagt accagatatg tgaaacagga gctgctaatt
    10021 caatatgtcc catgcgttca cggcgaactt tcgaacgagt aacttccact ccgcatcgat
    10081 cacaaacgat tcctttataa cggatacgtt tgtattttcc gcaggcacat tcccagtctt
    10141 ttgtaggacc aaaaatccgc tcacagaaca acccttcgcg ttcaggtttt aaggtacgat
    10201 agttaatcgt ctcaggtttt tttacttcac cgtaagacca gcttctgatt ttttcgggag
    10261 aagccaaacc tatttgcata ctttcgaatt tatttacatc gatcaaaagg ggttccctcc
    10321 atttcattta atggcaaacc gcaagacggc tgatcttcga ccgccttgca gctcatagac
    10381 cggattagtc taaattatct tctgcggttt caaagttttg gatgacatcg tctttttcat
    10441 cttccacttg ttcagcagct ttcttttcta attctttggc agtttgctgt tcggcaaatt
    10501 ttgtcaaagc atcaacagtg atcaaatcgt cgtcttcatc gtccatgtcg cgaagttcga
    10561 tctctgtttc ttcgatatcc aagacacgca tgtccagacc tagtgattgc aattctttca
    10621 ccaatacgcg gaatgattcc ggtacacctg gttttggaat tggttcaccc ttgacgattg
    10681 cttcgtatgt tttcacacgt ccgactacgt catctgattt gtatgtcaag atttcttgta
    10741 aagtataagc cgcaccgtaa gcttccagtg cccatacttc catttcacca aaacgttgtc
    10801 caccaaattg agctttacct cccaatggtt gttgtgtaac caatgagtaa ggtccgattg
    10861 aacgtgcatg caatttgtca tcgaccatgt gagcaagttt gatcatgtac atcacaccga
    10921 cagacacacg tccatcaaat ggttcacctg tacgtccgtc gtacagaaca gttttcgcat
    10981 cgctggccat accggcttca cgaactgttt cccatacgtc ttcatcactt gcaccatcaa
    11041 atactggcgt tgctacgtgg atacctaact gacgtgcagc catacccaag tgtaattcca
    11101 atacttgccc gatgttcata cgtgaaggca cccctaaagg attcagcatg atatcgattg
    11161 gtgttccatc aggtaggaat ggcatatctt cttccggcat aatacgggat acaacccctt
    11221 tatttccgtg acgaccggcc attttatccc cttcatggat tttacgtttt tgaacgatat
    11281 aaacacgaac taacatgttt acgcctggtg acaattcatc tccagcttca cgagtaaaga
    11341 ttttcacatc gtgaacgata ccgccgccgc catgtggtac acgtaatgat gtatcgcgga
    11401 cttcacgagc tttttcgcca aagatcgcat gcaatagacg ttcttctgca gataattctg
    11461 ttaccccttt tggcgtgact ttccctacaa gcaaatcgcc atcttggact tctgcaccaa
    11521 tacggatgat acccatttcg tctaaatctt ttaatgcgtc ttccccgaca ttagggattt
    11581 cgcgtgtgat ttcttcaggt cctaattttg tatcgcgggc ttctgattca tattcttcaa
    11641 tatggataga agtgtatacg tcatctttta ccaaacgacg gctcatgatg atcgcatctt
    11701 catagttgta cccttcccaa gtcatgaaac caactaaaac gttttggcct agagccattt
    11761 cgccttgttc catagatggt ccgtctgcca gagtatcccc tttttcgact ttctcaccca
    11821 aatgaacgat tggacgttgg ttgtagcttg ttccggagtt tgaacgacgg aattttgtta
    11881 catcgtattt atctaatgca ccgttgtcgc ggcgtacgcg gatttcagaa gcatcaacgt
    11941 attcaacgac accgtcatgt ttacataaca aagcagctcc tgagtcatgc gctgatttgt
    12001 attccatacc agtaccaacc catggtgctt gaggattgat caacggcact gcttgacgct
    12061 gcatgttggc acccatcaag gcacggttgg agtcatcgtt ttccaagaaa ggaatacatg
    12121 ctgtcgcaac ggcaactact tgtttaggtg atacgtccat gtagtctact ttatcaatag
    12181 atacttctaa gttttcactt tgagcacgag ccataacaac gtcttgagca aatgttccat
    12241 cttcattcaa tgggctgttt gcttgggcta cgatgtaatg gtcttcgata tcagctgtca
    12301 agtagtcgat ttggtcagta acacgacctg tttcacggtc tacacgacga taaggtgttt
    12361 cgataaatcc gaatttattt actttcgcat aactggacaa actattgatc aacccgatgt
    12421 ttgggccttc aggagtttcg atcggacaca tacggccata gtgggagtag tgaacgtcac
    12481 gaacttcata accggcgcgg tcacgagtca atccgccagg tcctaaggct gaaagacgac
    12541 gtttgtatgt caattcgcca agagggtttg tttgatccac gaactgtgac aactgagaag
    12601 aaccaaagaa ttctttgata cttgccacaa ctggacggat attgatcaat tgttgaggtg
    12661 tcaatgtttc agtatcttgg atcgacattc tttcacgaac cacacgttcc atacgtgcta
    12721 gcccgatacg gaattggttt tgtaaaagtt caccgactga acggatacga cgatttccta
    12781 agtggtcgat atcatcgaca ttgccgatac cttccatcaa gttcaagaaa tagctcattg
    12841 aagcaatgat gtcggctgga cgaaccgttt ttacagctgc ttctggatag ccgtttccga
    12901 tcacgtttac ttcacgttca gggtctcttg gtgaaaatac tttgatgact tggacagtca
    12961 ttggatctgt gaccacaccg tcttctgatg gatagtaagt cactgaattt aggccattat
    13021 caatgaaagg agctagtgtt tccatgactt ggtgagtcag aactgttcct ttttcaacga
    13081 tgatctcgcc tgtttctgga tcaactaatg tttcagctaa tgtcagattc aatagacgtg
    13141 ttttcaaatc taattttttg tttactttgt aacgaccaac gtttgctaag tcgtaacgtt
    13201 ttggatcgaa gaaacgagca ttcagcaagt tacgtgagct gtctgctgtt tttggttcgc
    13261 ctggacgcaa acgttcgtaa acgtctttca aaccttcttc tgttcttgag tcgcttgcgt
    13321 ttttatgcaa gtctttttcg actgtattgc gtaatgtttc gctgtcgccg aagatttcaa
    13381 agatcgtatc atcggaacca aatcctaacg cacgaactaa tacggttaaa ggaatcttac
    13441 gtgtacggtc gatacgtaca taagagatgt cttttgcatc agtttccatt tctagccaag
    13501 ctccacggtt agggataaca gtagaaccga atccttcttt tccgtttttg tcgacttttc
    13561 catggaaata gacacctggt gaacggacta actgagaaac gattactcgc tctgccccgt
    13621 tgatgatgaa tgttccttgt tctgtcatta atgggaaatc accgaagaat acttcttgtg
    13681 ctttgatttc gccagtctcg cggtttgtca aacgcaatgt tacatgtaat ggtgcagagt
    13741 agtttgcatc atgcgcacga gcttctgcta ctgtatactt tggttctttc aattcataat
    13801 ctacaaattc caaagataga ttgccattga agtcatcgat tggcaaaatg tcttcaaaca
    13861 tttctctaag tccctcatct aagaaccatt ggtaagagtc tgtttgaatt tcgatcaaat
    13921 ttggtaattc caacacttca ctgattcttg cgaaacttct acgttcgcga tgttttccgt
    13981 attttactac gtgtccagcc aagctcttca cccctctaaa atgtcattca aaaagactac
    14041 ccgatcaatt gttacaataa tatttcaaat attattttta ggtaacaaca gacatttttt
    14101 gcggctttta ggcaaaaaaa aaccaaaaat agaacattct cttgaaacct tacttcgtga
    14161 gcttctactt ttgtttcctt atattaaagc cgaaacggac aatatttcgt ttctgccttt
    14221 tcttcatcag atagtttttg caacttcata tactacactt attttctata aaagtcaaca
    14281 cttcctggcg tttcttctgc tttttcgcaa cattttctta atgttttcaa ttttatgttt
    14341 tcaattatct gacaattctt aattgacaga cctttttatc tcggttatac tttagaaaat
    14401 tcattttgtg gaggaacttc tatgcgaacc aacatcaacc aaatcgcacc aacacaactg
    14461 aataactttt actttagcta ctttagatag gtttgtattc atcatgatgg atacaaacgt
    14521 taaacgacag tttgtatcta tgatggctaa agaactttgt attgcagcaa aaagccacgt
    14581 agacaaaatg ctaagtggct gagcagtgaa aatacaaagt aaaagtatca agcattctac
    14641 tttttcaatt tattttccga cttttcaatc catttggaca ttttgtctga atggattttt
    14701 tgtttcccaa aattaaggag gaaaaagaaa tgaaaaaaaa tataatcatc ggattaggcg
    14761 ctgccctgct actagcttta ggaggttgcg cacaaaaaga caattccgca gaggcatcag
    14821 atggacaaaa aacaattggc gtattgcaac ttgtacaaca taactcgtta gatgctgcct
    14881 ataaaggatt caaagaagga ttagcagaag aagggtataa agaaggcgat aatctaacaa
    14941 tcgattatca aaatgcccaa aacaatcaag acaacctgaa aagtatgagt gagaaactcg
    15001 tcaaagaaga tcctgatttg ctacttggaa tcgccactcc agcagcacaa tctttattaa
    15061 atgaaacaac cactatcccg atgactgtca cagcggtcac agacttggaa caagcccatt
    15121 tagtcacatc caatgaaaaa cctggcggca atgtgactgg cacgacagat atggtgccaa
    15181 tcgaaaaaca aatcggctta ctgttaaata tcgtgccaga cgccaaaaca atcggcatca
    15241 tgtataacaa cggtgaagca aactctaaga tccaagctga tttggcagaa aaagaattga
    15301 aaaaagcggg cgtcaaagtc aaagtactga cagcaaattc cacaaatgat gtccaacaag
    15361 tgacgaaaag tctagctaaa gatgtagatg gaatctatat tcctactgat aacacgttcg
    15421 caagtgcggc aagtgttgtc ggtgaagtcg caaaagaaac aaaaacacct gtcgttgctg
    15481 gcgcagttga tcaagtcaaa gacggcggtc tagcaacagt aggaatcgac tacgaaagct
    15541 tgggcaaaca aacagggatc atggcagcaa aaatcttaga cggcaagaat ccaagtgaac
    15601 ttcctgtcga aacagcgaat gatttggaac tgtatgtcaa taaagacatg gccaaagcat
    15661 taggcatcaa tccagacagc atcaaagaag ctgaataaaa cacaggagga ttctcatgac
    15721 aaatttgctc tctcttttct tatcatctgc atcgcaaggg gtcttatggg ccctacttgc
    15781 gattggtgta tacgtcactt tccgtatctt ggacattgcc gacttgactg ctgaaggaag
    15841 ctttccttta ggtgcaggga tcgcggcagt aagtattaca aatggctatc atccattgac
    15901 agcttgtctt ctaggctttt tagggggtgc ggcagcaggg cttgtttccg gactgcttca
    15961 cacaaaattg aaaattcccg cccttcttgc agggatcatc accatgactg gtttatattc
    16021 tgtcacatcc cgtgtgatgg gtgcgccgaa catctcttta ttgggtcagc caacgatctt
    16081 tcattgggtc gagtcattcg gcataacaaa agacaacgct gtactgatcg tcggtctgct
    16141 ttttgctttg atcgttgtat gtttacttgt tttgttctta cgtacagaaa caggacttgc
    16201 tattcgtgca actggcgata atctggcaat gagcgaagca aacgggatca acacagataa
    16261 tatgaagatc atcggttata tgatttctaa tggatgcatt gctctttctg gctccttgct
    16321 tgcgcaaaac aacggctttg ctgatttaaa ttctggtatt ggaacgatcg taattggact
    16381 tgcttctatt atcatcgcag aagttttgtt acgtaaccag ccactatttc tccgtctctt
    16441 gactgtcgtt ttaggtgcgg tcatttatcg ttttatttta gcgttagtct tcgaactgaa
    16501 tgttgaacca agtgattcga aacttgcttc tgctttcgtg ctagtgatct gtctttcttt
    16561 cccgcagatc cagcaaaaat tccatttacc tcaaaaaaag aaaggcggta gtgtcaaatg
    16621 aatgacgtct taacattgga aaatctccat catacctttg aaaaaggaac gatcaacgaa
    16681 aatcatgtcc tgaaaggcat taatctttcc ttagatcccg gcgacttcgt gacgatcatc
    16741 ggtggaaatg gggctggtaa atctactttg ctgaacagca tcgccggtac attttctgtc
    16801 gatcagggtc aaattttatt gaatggaaaa aatatcacga aaaaatctgt tgtcgaacgt
    16861 tcgaaatcca tcagtcgcgt attccaagat cctaaactag ggacagccgt tcgtttaacg
    16921 gtagaagaaa atcttgctct tgctatgaaa cgaggaaaaa aacgcggctt cttccgtggt
    16981 gtcaaaccac aagaccgaac atttttcaaa gaccagctgg ttcggctaaa tttggggttg
    17041 gaaaatcgtt tatcctcaga aatcggtttg ctgtctggag gacaacgtca agctattacg
    17101 ttattgatgg ccacattaca gcgtccagaa ctgatcttat tagatgaaca cactgcagcg
    17161 cttgaccctg ctacttccaa aacggtgatg gaattgacag aaaagctgat cactgagcag
    17221 aatctcactg cttttatggt cactcatgac atggaagacg cgatccgcta tgggagtcga
    17281 ctgatcatgc tgcatcaagg aaggatcgtc gtagatatcc agcaagagga aaaacagcag
    17341 ctcacagtgc cccaattatt agcgttgttc aaacaaaaca gcggcacggc attaaaagac
    17401 gatcaagtac ttttatcttc ataatcagaa agaggatggg acaaaaaatg aacgcccacc
    17461 ctcttctttt ttctctttcc ttctttcgtt tttgctttat gtatcaaccg ttgtttcttc
    17521 gaaaactatt ttgttctctc cttcttcctg atagaatgga tgggaaagga gcttgatgcc
    17581 atgacaacga aagacaaggt acttcaatta ttgaaaaaga caccagattt tctttccgga
    17641 gaaaagttgg cacagcaact ggaagtttcc cggacaagta tttggaaagc catcaaagaa
    17701 ttggaaaagg caggctatcg ttttgagcac gggcctacag ggtatcgtta cctgccctct
    17761 gacgtactag atgcaaaaga aatccagcaa gagctacggt cgtttattcc tgatttgaaa
    17821 gtacaaacga tgttgacttc tgaatctacg atgaaagatg ccaaactggc agcagctcaa
    17881 ggagattctg tttcgaagtt atttgttgct gatacacaag aacaagctcg tggacgtttt
    17941 ggacggcctt ttttcgctga acctggacga ggaatctaca tgagtctctt gctccatcca
    18001 gacaaacggt ttgatgaatt gcctcaatat acgatcatcg cagccagtgc ctgtgtgaaa
    18061 gccattgaat ctgtaaccgg tcgttctgct tcgatcaaat gggtcaatga tatctacatg
    18121 gatggaaaaa aagtctgtgg gattttatct gaagcagtca gtgatatgga aagcggcagg
    18181 atcagtcata tcatcattgg gatcgggctt aatttttctg ttcctcaaaa tcattttcca
    18241 gctgatctcc aagaaaaagc catctctgtc tttcccgacg gacaagctag tgtcacaagg
    18301 aatcagctaa tcagcaaaat ctggcaagaa ttgttcactt atctttctca cccagaaaaa
    18361 gcgttggact tctataaaga aaaatcattc gtattgggaa aaaccgtgtc gttcaatcaa
    18421 aaaggaacga cttatgtcgg tcttgcaaaa gaaatcggtg atcatggcga actgatcgtc
    18481 caaacaaatg aacagaagat gagtttgtct tctggcgaaa tcagtctcac atctatccgt
    18541 acgcaataat tatcagattt cacaaaagga cacctgatct catacagtgt ccttttttct
    18601 gaattctctt caaaagactc tccttattct atcagctgac agtttctcta tcctctagaa
    18661 aaaggtattc taaaaatatc tataaagcat ggtacacttt ctttaaatga atcaatgcaa
    18721 aaaacaagag agtcatcagt ttacacgatc aaaagagata gcaggccgct tcctttttca
    18781 atcttataga tagaccatgg gtaacgataa aaacaaaaaa gaacttgcga cttattttgc
    18841 cgtaagttct tttttagcta gtgccttaat ctcttaatcc caacaaacgt ctcgcataga
    18901 tcacctgacc agagtgcata gcagcatcat caataataga aacgagacgc attcctcgtg
    18961 tgactggtgg tgtccagttc tcgtcaatta cttcatctag ctcggaaggt tccagccttc
    19021 ttaagtaaga aatagcaaaa tcagcagctc ctcgcaagta tcctagcaga tcttctattt
    19081 gattagcttg gatctgcttt gcttgttcca gactatgctt ccaatcttgt tcgttatctg
    19141 ctatcgtcat cggaaaccgg ctttcccagt cttgactatg ccaaattgga gaagttcctg
    19201 ctaaatcagc aatctggaaa tctaattctc gagcggtatg ccaagccagc caagtcattg
    19261 atttgatctg cggggctcta tcttccactg gaaaacgatt ggcctcctca atagagacgc
    19321 cttcaaacaa acgttcaaac cgatcgtatg cccgatccac actctcgcat agcatatcta
    19381 aataatccat ttattttcct cctttttatt tatcctactt actttttcct aattctagga
    19441 tacctactta tatgttacta cacaccctta ttttttacac tttaacagtc accatcatca
    19501 atagtttgga gattgaaaga aaaagatagt gtcgaactat caattgaaca agaagcaaca
    19561 atatgaacgt ttcattaata ttctttaaat aaacaatgat ttttcaaacg aacagtttaa
    19621 gactaggaga aaaagagtat aataggaaaa tgtttgaaag gaaaggaagg ggaaaaatga
    19681 aaaaaagggc aagtttacta gtcctagttg ctttgttgtt caatatcttt tcgtatggtg
    19741 tggccgtttc agcggaaaca tacattccta aagaccctgg gaatatttat aatgatctaa
    19801 ctggtaacta tggcttgtta ggaattgcta gtcaattcca cgtatttgct aaaaataaga
    19861 caactgtgaa tgcacataca gacggaaata tagcaacaca tgaacttgat gcaaaaaata
    19921 attttggtac agagcttcat gaaggtttat tgaaccaaga aataaattat atacaaaaaa
    19981 ctgattcttt cgctaattct tcaggcatac ctacaggtag cacaagaatg aataaatttg
    20041 tcgttggcag taacgtggat gtagcacttc aagatggtca tcctacagtc aatggatcca
    20101 ggcttgatca cttaactcca gatgattttt ataaagatcg tgctgggcat gaatatattg
    20161 atttcgagca ggaatttgct aaattgaatg tagcagcaaa tgatcttgca acgatcactc
    20221 cagctaaaac atatactgct gcagattttc cagacatgaa caatcggaca atcgatttaa
    20281 ctgatttatc agataccggg tttttattgg taaatatcga tgcagaagtg ttaacgatga
    20341 atacgccact tcaaatcatt aatccaaatg atcaagtagt tgtatttaat gtcatcaaca
    20401 gttcttctgc attgaacgta cagtcaccaa tcaaatacaa tgatcgttca aatcatgaaa
    20461 cagaagattt ttcggatgcg aatatctctt ggaattttgg aaatgagatg actgatttga
    20521 caatcagtgc tccttttcaa ggaacaatcc ttgcgcctaa tgctactatc cgcattactc
    20581 aaaaccaaga cggaacgatt ataggaacaa atgtgatttt agatgcagct accaatcgtt
    20641 gggatcctaa cgaaatattt atcagcgaca atggtacaga tacgacagac acaagcgaca
    20701 gtacagatac atctaccaca agtgatagct cagattcatc aacttcaagc gacagtacag
    20761 atactacctc taccacaagt gatagcacgg atacatcagc ttcaagcgac agtacagat
//
LOCUS       DAKCAA010000047        19593 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000047 DAKCAA010000000
VERSION     DAKCAA010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.047"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(334..696)
                     /locus_tag="OUE31_001900"
     CDS             complement(334..696)
                     /locus_tag="OUE31_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222892.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(770..1150)
                     /locus_tag="OUE31_001901"
     CDS             complement(770..1150)
                     /locus_tag="OUE31_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HCU0222893.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1214..2407
                     /locus_tag="OUE31_001902"
     CDS             1214..2407
                     /locus_tag="OUE31_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCU0222894.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2484..3068)
                     /locus_tag="OUE31_001903"
     CDS             complement(2484..3068)
                     /locus_tag="OUE31_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCU0222895.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3269..4267
                     /locus_tag="OUE31_001904"
     CDS             3269..4267
                     /locus_tag="OUE31_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCU0222896.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4379..4888
                     /locus_tag="OUE31_001905"
     CDS             4379..4888
                     /locus_tag="OUE31_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HCU0222897.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4918..5577)
                     /locus_tag="OUE31_001906"
     CDS             complement(4918..5577)
                     /locus_tag="OUE31_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HCU0222898.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5579..6343)
                     /locus_tag="OUE31_001907"
     CDS             complement(5579..6343)
                     /locus_tag="OUE31_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HCU0222899.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6351..7028)
                     /locus_tag="OUE31_001908"
     CDS             complement(6351..7028)
                     /locus_tag="OUE31_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HCU0222900.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7065..8450)
                     /locus_tag="OUE31_001909"
     CDS             complement(7065..8450)
                     /locus_tag="OUE31_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCU0222901.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8660..8744)
                     /gene="ffs"
                     /locus_tag="OUE31_001910"
     ncRNA           complement(8660..8744)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="OUE31_001910"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8767..9282)
                     /gene="tadA"
                     /locus_tag="OUE31_001911"
     CDS             complement(8767..9282)
                     /gene="tadA"
                     /locus_tag="OUE31_001911"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HCU0222902.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9389..10246
                     /locus_tag="OUE31_001912"
     CDS             9389..10246
                     /locus_tag="OUE31_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222903.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10327..10662)
                     /locus_tag="OUE31_001913"
     CDS             complement(10327..10662)
                     /locus_tag="OUE31_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222904.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10729..12099)
                     /locus_tag="OUE31_001914"
     CDS             complement(10729..12099)
                     /locus_tag="OUE31_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HCU0222905.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12177..12713)
                     /locus_tag="OUE31_001915"
     CDS             complement(12177..12713)
                     /locus_tag="OUE31_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCU0222906.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13022..14503
                     /locus_tag="OUE31_001916"
     CDS             13022..14503
                     /locus_tag="OUE31_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222907.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14606..15313)
                     /locus_tag="OUE31_001917"
     CDS             complement(14606..15313)
                     /locus_tag="OUE31_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HCU0222908.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15392..15730)
                     /locus_tag="OUE31_001918"
     CDS             complement(15392..15730)
                     /locus_tag="OUE31_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HCU0222909.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(15841..16803)
                     /locus_tag="OUE31_001919"
     CDS             complement(15841..16803)
                     /locus_tag="OUE31_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HCU0222910.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(16818..18149)
                     /locus_tag="OUE31_001920"
     CDS             complement(16818..18149)
                     /locus_tag="OUE31_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCU0222911.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18157..18837)
                     /locus_tag="OUE31_001921"
     CDS             complement(18157..18837)
                     /locus_tag="OUE31_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCU0222912.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19056..19535)
                     /locus_tag="OUE31_001922"
     CDS             complement(19056..19535)
                     /locus_tag="OUE31_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HCU0222913.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
BASE COUNT         5845 a         4032 c         3242 g         6474 t
ORIGIN      
        1 aacgactcag ttatcttatc atgtcgttag taacatgtca ataactattt tttaaatttt
       61 ttagaaatgt gatataacat ccacttcaga atcaacgctg ttaaatttat catgtatttc
      121 ttccttggtc aactataaat taagcattac tttgtgaaat gatttttcga tcaattatta
      181 ttattcgtta tacaaccgtt ttcaacatat tttgaaaata aaatgcacta aaaaactatc
      241 tttagcagaa catttcattg tattttttgg accaaacaat aaaaaaagaa gtttgaaaaa
      301 aattcaaact tctttgttcg cttaatctgt attttagaag aaaggcactc cctctacttc
      361 gtaagttcca agaacagagc gcatttgacc tggttcttcc caaatatatc cttcgcctaa
      421 ttcttctctt tgattctttt gttcagtttc aaagacaaac aacggaacat tttcctcttt
      481 aatatgtgta tttgtcaatt ccatcaaact aatcttgcta acatcgatat gaactatttc
      541 ttttaagaaa ttaagtatat tcgctaaacc agtctttcct tcagaaagtt ccgctaacgc
      601 aaattccaac ttgtcatcaa ttgaatggac caaaaatttt ttagtaccat cctccaaatg
      661 caacataatt gtaccagcaa ctcttttgct tgccaaaatt tccacctcga tcaacttgtt
      721 ctatggctta cataaaaatt ctagcacatt ttcagaaaaa atacactttt tatttcttat
      781 tttctttccg ttctagttca gataatgctt cttctatcca aataggtaac tgctccgcaa
      841 tagtggtaaa tccgatctta cgatttttat tcgtgaaata cctttttctg cgatatggaa
      901 cagctggatt tgttttttct aacgttctta aagataaact gatttttttg gaatattcat
      961 caatgtcgat gatctgaact gttactggct gtccgacttt taacaatgaa tggatatttt
     1021 tcgtataacc ggattgtact tctgaaacat gaataagtcc ttgcgtctcg ttatcaagag
     1081 aaacgaatgc gccataaggc tgtatccctg tcacttttcc ttcaattatt tgtccaattt
     1141 tataagtcat ctacttccct ctcttcgcat ttatcattat actgtaaata gctcaaaaaa
     1201 agaagcgacg aaaatgactg gaggtcttaa gatgatcgaa tttgataaac agatttcaag
     1261 aaaagataca gaaagtgtaa aatgggacgc aattgctgag acatatcaaa tggatgactt
     1321 acttcctttg tgggtagcag atatggactt cttgtctccc ggtggggtag ctaaagcgtt
     1381 tagtgaatac atcaaacatg gaatctttgg ttatgccact ctgtctgata aactatatca
     1441 ggctatcatt cattgggaac gccaacacca tgctgtggag ttgacgaaag aaaatatcgt
     1501 ttttacaagt ggtgtgttaa ccagtttagc tgcagcagta caaactttta caaaaccagg
     1561 cgattctatt ttgattcatg acccagttta tcctccattt tcctctatta tagaaacaaa
     1621 tcaacgtcac atcgttcgaa gctctttgct agaaaaaaat aatcatttca tcatggactt
     1681 gtctgacatg gagaaaaaaa tcgaagaaaa caatgtaaaa gcaatgattt tatgcaatcc
     1741 tcacaatcct ggagggcgtg tttggagcaa agaagaattg aaacagttaa gcgaattgtg
     1801 tttaaaacat caagtgattc tgtttagtga cgagatccat caagatttaa ctttattcga
     1861 tcatacattt acttccatgc taacgattga tcctaattta gatgatctac tagttgcttt
     1921 tacttccgca accaagactt tcaatctagc tgcaatcaaa aattcaatgg tatttatcaa
     1981 aaatccagag atgaaagctg attttgaaaa acatttagtg atgaaccaac agcacgaaat
     2041 caacactttt ggactgattg gaacccaagc ggcttatgag acgggtggag aatggttaag
     2101 ccaactgatt ccttatctag aaaaaaatgt tcaaacagtt aatcagtttt ttgaacagta
     2161 tcttccgaaa gtgagaataa tgaaccctga aggaacttac ttaatgtggt tagattttac
     2221 cgcctatatt tcagacgacc aagaattgga gaacactctt gttcggaaag gaaaagtcgt
     2281 attaaatcct ggcatcacgt ttggtccttc cggtcatggg catatgcgct tgaatattgc
     2341 ttgtccagaa gaaactttac tggaaggact taatcgaatc aagtatgctt tagagacaat
     2401 cgattaaatc atttattcaa aataaaagga cgagacctta ctaggtttcg tcctttttca
     2461 taattactcc gtaccatacc aaactattct gaaatttcaa ttgtttcaat cactacatca
     2521 tgtacaggtc ggtcttgtgg accacgttgt acatttgcga tttcatctac tgtgtccatc
     2581 ccttctagta catgtccaaa gactgtatgt cggaaatcta gccaaggagt tccgccacct
     2641 ttatacgctt caatgatttc tgatgggaat ccagcacctt ctagttgtcc aagcatatta
     2701 gctggcacat ttgtgttatt tacaataaag aattggcttc cgtttgtgtt tggacctgaa
     2761 tttgccatag ataaagctcc gcgaaggttg aacagttcac gactgaattc atcttcaaaa
     2821 ctttcgccat aaatactttc gccacccatt cctgttccag ttggatcgcc gccttggatc
     2881 atgaaatcag gaataacgcg gtgaaaaatc acgccatcat aataaccttt tttggaaagt
     2941 tcaatgaaat tttgaaccgt cttcggtgct agttcaggga ataattgaac agtaatgtca
     3001 ccacggtttg ttttgataac agcttttggt cctttttcac tttttaaatc tagttgtggg
     3061 aatgccatat tgtttcctcc taatatttgc atacttcata ataataataa cataatacct
     3121 aacctctcgt aaaaatacta gatttgtttt cttttatttt tcatcactag atacattcta
     3181 taacttaccg tttcgatttc gaattcaaac atttttgaga agcattctca attaaattct
     3241 gctatagtgt gaaaagggag gaatttttat ggaaatctat gacattacaa tcatcggtgc
     3301 aggtcctgta gggatgtttg ccgcttttta cgcaggaatg cgccaagcta aaacaaaaat
     3361 cattgacagt ctacctcaac ttggtggtca attagcaact ttgtatcccg aaaaatatat
     3421 ttacgatatt cctgggtatc cagcaataaa agcaagtgaa ttaatcgatc aattagaaaa
     3481 acaattaact acttttaacc atacattcca tttaaaagaa gaagttctct cgcttactcg
     3541 tgaagacgaa gttatcgaga ttactacaaa taaaggcatc cattattcca aagcagtcat
     3601 tttagcttta ggaaatggtt cattccagcc aagaaaattg aatttagata atgctgaatc
     3661 atttgaaaac cacggattgg attatttcgt gaatgatttg atgaagtatg ctggaaaaaa
     3721 agtcgctatt gctggaggtg gtgattctgc tatcgattgg acgttgatgt tagagcctat
     3781 tgcaagcgaa gtttacttga ttcatcgtcg cccggaattt cgtgcgcacg aacatagtgt
     3841 atcacgcttg aaatcttcat ctgtcaactt gcttactccc tatctcatcg atggattatc
     3901 aggcaataat ggggaactga cagatatccg gttaaaaaaa gtgaaaagtg acgagacgat
     3961 tgatttgatg attgattctc tgatcgtcaa ttatggattc tcttctaatt tagaacatct
     4021 ttcttcttgg ggacttgata gtaccagaaa tgccattact gtaaaatcag atatgtctac
     4081 ttctattcca ggcgtttatg cagctggtga catctgtacc tatgaaggaa aagtgaaact
     4141 gattgctact gggctcggtg aagcacctac tgcagtgaac aacgctttac actatattaa
     4201 tccaaaggaa cgaactcagc ctggtcacag cacaagctta tacgataaaa atcttcgtcc
     4261 tagttgattt tttatatctc tttgcatttc aagttaaacc cgaaagcagt ttcttgcatt
     4321 tttttcatgt tccgttaaca tgaaatagag aaagaaaaaa taaaggggga gcaataatat
     4381 ggtcgtcaaa actgagactt tagaagaaaa ggcaagagaa ctattgaagg aacgtggcgt
     4441 aactgtagaa gatatcgcac aacttgtcat gtttttacaa aaagactata tttctgattt
     4501 gactttggcg gattgtactg aaagtgtcaa cagcgtgcta acaaagcgtg aagtacataa
     4561 cgccattatc actggaatcc aattagatat attagcagaa aagaaaaaat tgatgagtcc
     4621 gttgcaacat attatcgaag atgacgaagg cctttacggt atcgatgaga tcctagcctt
     4681 gtcaatcgtg aatgtttacg gtacgatcgg ctttacgaat tatggttata tcgacaaggt
     4741 gaaacctggt attttaaaag aactaaacag ccacgatggc gttcatgtcc ataccttctt
     4801 agatgatatc gtcggagcga tcgccgctgc tgctgccagt cgattagcac acaaagaacc
     4861 agaaaaaaga agtcgcctta ctcaataatt caacaaaaaa agaaagaaaa cgtctattta
     4921 gacgagttct ttcttttttg tttgtttcaa gctatttttt cctaagaaaa gaaaaacagc
     4981 aaaaaataat tctaataata caaaaaataa gataaagcta tgcatgaaaa attcttctgg
     5041 aagtacattg atgattggat cagtaacggg atcgaataac cagtcatcgt tgttgaaaaa
     5101 cgtttcatga aaaaggataa aaaagcgatc aaatcctatc atcatgaaaa aaccgaaaac
     5161 aactggcagt aacatgccga tttgaaacgg acgaatcaac cgccaaagcc gatcattctt
     5221 ttgcaaatat ttgataaaca aaatactcgg gatcaaagtg atgaaaaaca cagcataatc
     5281 cactaaaaac aaaattttca cttcataaaa gtgatgggct ccgctagcag aaactgggaa
     5341 atctggcaag ctgaggatgg ttttgaaggg attattgaga taattcatta ggtgatcaaa
     5401 atttttcagt aacgtctctt gatctaaaga agtataatcc aaaatttgca aatgtccgat
     5461 atcaaatacg tatagtggtc gaaagttgat cgtcacacca actgccagac tgatcagtgt
     5521 cagaaatagg ctgaacaatc cagcatattc catccactgc catctcgaat ttttcatatt
     5581 agaagctcca ttcatccagt gattgtttca cataggtagc tgggataggc aacccaggta
     5641 catcttcttc ttttgtaaaa cctgataaaa cgagcaaagt atctatatta ttgcgtatcc
     5701 cagcttggat atctgtttca tagttatctc caaccatgat tacttcttct ttttgcagcc
     5761 ctaatacttc aacggcttta tccataatga tggcttctgg ttttccgatg tagatcggcg
     5821 gcgtttgggt tgctgtctct acaaaagaga tgactgaccc tgctccagga agaaggccgc
     5881 gttcagtagg tatattctta tctgggttcg ttccaatgaa agtagcacct ttttgaatag
     5941 caagtgttgc tttaactact ttttcatagg tcagataatt atctaagcct accactacat
     6001 agtcaggagc ctcttcttcc catgtaaatc cggcagctaa aatcaagtca atcaatcctg
     6061 cttctccgat aacatagact tttttccctt ttccatctgc tttcataaaa tcgattgttg
     6121 ccaaagtagc tgtgtagact gtctctggag ctacatgaat gtcaaactca tctgctagac
     6181 gattagctac tgtttctggt gacttagtcg tgttattggt aacaaacaag aaaggtaatt
     6241 ttcttttttg caattcttcc acaaatcgtt taccggccgg tatgggttgt gtcccacgat
     6301 aaatcgttcc gtctaaatca attaaatatc ctttatagtc cattcatcca ctactcttcc
     6361 ctttttctga tcgtaaatgc tgtttttgtt ttttctactt gtttaggttg ttcttgtttt
     6421 tttacttttt cagaggtttt tgctgactct gtttttcgat ttttaataac cggttttttg
     6481 cgattagatg cgactggtcc ttttttctca tcgatatacg cacgattatg gttttttttc
     6541 ttttttcggc gctgagttgt cttttctttt ttaccgccga ttctctcgat gacaaaatac
     6601 gcacaaccaa aattgcaata ttcgtaaaga tagtcttcca aggaatcgat tcgctgatct
     6661 ggatgcgccc gtcgattatc cgcttggaaa aatcctttta ggcgtagttg ttcataaccc
     6721 caatctccta cgatataatc atatcgggct agtacatcac tgtaacgttc tccaagcttt
     6781 tctgcattaa atccttcacg ataatcggac acaagccgat aatgtctttc acctatcaaa
     6841 aaattactgt catctaacag tgtcactagc tcgcctttga ctttttctgc tttaggctcc
     6901 tcaacgattt cttccaaagc agctgtcagt tcttcggtga ctgttgtttc ctgttcagct
     6961 gatgattttt tcttagcaat ttctgtttta tgctcaacgt tctgctgttc attttgtttt
     7021 gcagacatgc gttcaccacc tatctttttt attatacctt gtttttattt gattgggtag
     7081 tgagctttca agtaatctcc taccacactt cggataaatt cagggaacaa aaattcattt
     7141 tttccagcaa tctcaatcgt tggaaaaaat ggaacaaaca tcaaatgatc tacggtagta
     7201 aaagtataat ttttattcag atcgattggc ttgttcttcc aaaagacttg atggttaata
     7261 gaatcatatg tgattccatt atagaccatc tgcccaaaaa tcttaccgcg aaatcccatt
     7321 cccttcatag gatagttacg taaaaagtta cgattttttt ctatttctaa aactaagcgg
     7381 atcagatcat ttccacccaa tgtgacattt aacaagtgca tcggatgcgg caacgcagtg
     7441 tgaagctgat cctgattgac ccgccctttt ggaatttcag ttaaaaacag accactgttt
     7501 aatattgctg cttccgtctt tcctcgttct ttcaccgcct caaaggctac ttggataaac
     7561 gaatgctcat tgaagatatc tagactcaga gaaaatggca aatctgctac ttctttttct
     7621 tttaataatt catgcccacg ttctagataa ctatttattt cttgttcatc ttctgtaaaa
     7681 gctgtcattg tttcggtagg gatggctttg gctgaatgct taaggatttt tttctcttca
     7741 tcgatggtta aatggacttc accgacatac tgcccgtact ttccagcggc tgctatttgg
     7801 acatcattga ttacgtgacc ttctctgaat aaatgatggg tgtgcgatcc taaaataaca
     7861 tcaattgctg gtatttcttt tgcaatttgg aaatcatcct gaatcccgag atgactcatc
     7921 aaaactaaaa catccacttg tgaacgtaaa tcttcgacta attctggcaa aatatcataa
     7981 ggattccgta tgtcccagcc attcggatta taagtaagcg gaaatggagc agtaaatgca
     8041 attagtccga ttttcgtctg gtgtttcgtt gtaatgattt tatatggttt cgtccatgcc
     8101 ggtggctgga gcgtattttt atcgaataag ttatccagga tgatatcaaa ctcagcatga
     8161 tcgtataaat gattcaactc ttctttggaa tttcctacgc cttcattgtt tcctatcgtc
     8221 gctgcatcat aaccaacttc attcatcagc aagatatttt cctgtccatt cgttgcttct
     8281 gacaatggat gccaacgatc cacaaaatca cctagatcta ctgcaatcgt tgtcgttttt
     8341 tctttctttt cgttttctcg tttacgttga tccaaaaacc ttctgatcct tggccaattt
     8401 tctaaatgag aatgcagatc attcgtatgt aaaatcacta ttttttccat gtaccctctc
     8461 gcctctcttt atctttatca taccataggc agctttttct tccattgaaa caagctctat
     8521 ttcagagttt ttcctgcctt gaagcaaatt gtataagtac aatattcgat aaatcagtct
     8581 ggctaaaaaa tcaggaacat tcatttttac agtactataa aaataaaaaa aacagacccg
     8641 aaagtctgtt gtcgtttcat tataatcaga cacatggcgg aacctgctta gtgctgcttc
     8701 cttccagacc tgacacgctt cacaagccca ccattgtcct agcctttcgg caaagaatag
     8761 tataccttat ttttcattcg ttgaccagtc tttttttaat ttcttttttc gctggcggag
     8821 ctttcggaaa aagtcagtca aaatcatccc acattcgtct tctaaaatgc caccttctac
     8881 atatgcttgg tggttaaacc gctcgtcctc caaaagattc atcaaggtac cggctgttcc
     8941 gccttttgga tcatacgcgc cgaaataaac ttctgctaca cgagacaaaa tcatcgcgcc
     9001 gctgcacata ggacaaggct ctaaggtaac aaaaagtgca gcatcttcca agcgccagct
     9061 tcccactttt tcacaggctt ccttgattgc aagcatttct gcatgtgtag tagcatcttg
     9121 cgtggtttct ctaaggttat atcctcttcc aatcactttt ccatccaata caaccactgc
     9181 tccaatcgga acttcatgaa gcatttctgc tttctttgct tctgccaatg caaggcgcat
     9241 ccatttttct ttttctactg catcaagatt tgtatttacc aattaccctt ccctgccttt
     9301 gttttttctt gttttacttt agcatatgat aaaaaggctg taactaactt ttttttctat
     9361 ggtaaaataa atacaagagg tgaacaagat gaaaatggat aaattacttg ctctttaccc
     9421 acaagcacag aaaaaaaact ctccagcatc agaagcggat atcctttctt ttgcaattga
     9481 tgatgctttt atctggatca aacaagattc attatctcaa caagaaacca gccttttgaa
     9541 agcgttattc cctgtaatca acgatcaaaa aaaacaccca tggtatcact atctttttaa
     9601 agatgcttct tgtgttcaag aaaaaagctt tcgtttgatc cagcttcacg tcgaatcaaa
     9661 aggagaattc ttaaaaaaag aatggcaaga tactattttg gaattatttc gctattctgc
     9721 tgatttcttt ttttatacag acacagatgc gctcttagtc gaacaaataa accgtgatta
     9781 tcttgatgct actgaaatca acggtatttt tctatcttta gatgctgatt ttgatacgac
     9841 aacgtctgta ttcgttggtt ctttccattc acctggcacc gacctcgtcc ctttgtttgc
     9901 tgaagaaaga aaaatttttt taacagagca aaacaatctt tatactcaca gccgtacttt
     9961 ttctatgcaa gatgtggctt tacattacta tacaaaagat actgtaaaag atagtaagtt
    10021 gatcaaaagt tacatagaac tgatcaaaca aaatgaaatg gaagtgatca ttcaagaatt
    10081 atggaatgaa ttaggcaatg tcagctctgc tgcaaaaaca ctgtttcttc atcgtaatac
    10141 tctaaaatat cgaatcgaaa aatttcaaga acagtctggt ttcaatctaa aaaaagccaa
    10201 cgatttactg ttttgctatc ttttattgct tcatgaacat aattaaagat agattaaagg
    10261 ggttgtgaca ataattttgt cacaacccct tatttcgaat gaatagtgtt caaaagctag
    10321 tttctcttac atcatttttt caacaaaatg cattagccgg tcttttacat cttcggttga
    10381 atctttgatt gaatcaccat aaacagagat tttctttttt cctgatttga tttttgctaa
    10441 cattcccatc aaagaatcca agtcactatc tgaaagacca tctacgattt ctagtaattt
    10501 ttcatttcca tcaaatttgt catagacgaa tttttttact ttcgtccgag tagtcatatg
    10561 atggatcttt tccattactt ttcccgatac aacgactgct gtcgctacac tggcagcggc
    10621 tgctacgctt aatccgattg ttacttttgt tgatgttttc ataagtatca gctccttttt
    10681 atctatctcc atcatagcat agacaaaaaa ataaacgaac taatccactc agtgaaatct
    10741 caatccttta gggaaaaagt tctttactgt tccttttact tgtttcccaa atccgacagg
    10801 tatcttatct aatactagca aaacccatcc ttgattccca tcacgttgaa atgtttctcc
    10861 tgctgtgtaa gattgccatt ccttttgagt gatcggcaag caaggtatat tctctatctt
    10921 ttttgtagca agcgctaatg catagctagg ttcaaatcga ttctttttga aatctcctaa
    10981 atgcaaacct gtacgtacga cttttaaacc atcgagagaa ggggctaact caggaacttc
    11041 ccaaagatgg tcgttgaaca ctaaaagtct tccagtagct tcataatgaa aatcatttga
    11101 aaactccgtc cagagttttt cctgctcttt tgtcatttgc actttacttt tttttcgtgt
    11161 cttcttttct ttatgcatct gattttgtcc atgaaaagtc agctttgcaa caaaatgtcc
    11221 ttcaccctga tctttatgag gccatatacg tattgttttt tccaaaccag ctacgcttcc
    11281 ccattcagaa cgtcctgaac taacggattg agtcaaagga atctcctcaa tcgttactgg
    11341 ataattttct acaagccagc taatgatctc ttcattttct tctggtgcaa acgtacaagt
    11401 cgaataaatc agttgtcctt tattttttag catttttatt gctgaagaca aaatctcttg
    11461 ctgacgtttt tgacagtata gcggagattc ttctgtccac tcttttattg catttggatc
    11521 ttttcggaac attccttctc ctgaacaagg agcatcaacc acgatccgat caaaaaagcc
    11581 cgaaaaatga gggacaagtt ctgcgggtgc atgatttgtc actattgcgt tcgaaactcc
    11641 ccatcgttct atattttctg ataaaatctt cgcacgtttc ggaaagatct cattcgtcac
    11701 taataaccct ttccccttca tttgagcagc taattgggtt gatttaccac cgggagccgc
    11761 acacaaatcc aaaacttttt caccgggttt tgctgcagca gctgttccaa cgatcattgc
    11821 acttggttct tggctatatt catacccagc ttgatggagg aaagactttc cattgacagt
    11881 gccaagaaat ccctcattgc tgtagggagc gggttgtaat tcttcgctat ggtaagtttg
    11941 gaccatgtcc aatcctgccg gttttagtgg attccaccga aatccttttt tcacgcttcc
    12001 ttgttcaagc gcagaaaaaa aatcggatgc ttcttcgcct aaaagaagac gatatttttt
    12061 gataaattgc tgtggtaacg ttgtcgcttc ctccttcatt ccaatgtttc gttagacatt
    12121 ttacaatctt ttttacgaaa aataaaggtg gctgatctac tttttcatgt tgctgcctaa
    12181 ggtgactgtt cctttaagat attttccaag tattcatccg tcacctcgtt tttatcccaa
    12241 acagcgttca tcatttcaag aaaatcttga gaagaatcat ctgagcgcaa acttcccaat
    12301 gcattaagcc ataccaattc aagcgacttt tcttctttga tcttcgtgtg acctttgaca
    12361 tatgagaaaa atggccgctt aaatagcgaa tccatgtcta aatcagattt tgcaatgatt
    12421 tcacgaatac tttcatggat agaaaaaaaa tctttcaata agtagacaat gcttaaaaca
    12481 tcatcggaac tgcattcagc taagtagttt tcaaaataaa cagtgatttc ttctaatatc
    12541 ttctctttta acccgctgat tgatttgaaa tgtgtataaa tcgggtatgt agaacaaccg
    12601 cagaactctg ctaactctct tgcagtaatt gacttcattc catattcttc cacgtatacc
    12661 atacttttga acagcaaata ttctttacta taatttgtta ctctccccat cattcttacc
    12721 tccgtctctt ttcatctacc cataaataaa taacataaat aattctaaaa atattattga
    12781 taattatcaa aacatattta gttatatcca ttaaaaatca atttttccgc cttaaaaaca
    12841 agaatatctt gacaaaatac cctaggaaat aaacaataga ataaacaagg taacaaaaaa
    12901 attaaataac gttatataaa aaagaaggcg acactctgtg agaataacac agactgaaat
    12961 gactttccac tcacagtttt tgtctaacta tatacaaaaa cagaataaaa aggaggtatt
    13021 tatgctaatt gaagcaagaa aaaaagagtt acttgttcta caaatggtca ttcaaaaaaa
    13081 taattgttct ttacaagaat tatccaatga cttacatatt ccaaaacgga caatcaaaga
    13141 actgatccga aaaataaatg tatcactcaa gcaattttta ttgattgatg aatttattta
    13201 ttctaatcat aaaggagaga tccaaaccaa agaaaccgat caaactaaaa agttagctgt
    13261 tttttctaag ttaaaattat gctacctaaa agaatccaat cgttttaact atttgatgtt
    13321 actaatcaat tatccacaaa ctgctgtacc aaaaaaatat ttacttgaac aactttatat
    13381 atcgccctcc tatctcgaaa aactgacaaa acagctcaat cattccttaa aaaaattcca
    13441 tttacggatc ctatctgtaa aaaattgctg tactcttgaa ggaaatgagt tatctatccg
    13501 tctctatctt tacttttttc tttcagatac atttggaggt aacgattggc cattttcctc
    13561 acttgaatta aatgcactaa aaatgaacag tacagatgag caaatagaaa aaatttcaaa
    13621 acaagaaaaa aatatctact tgctgttaac tttattcata ttacgaaaca aacaacaggc
    13681 atattttcca aaaacttctt ctgaaatcac tgaattgatg gacttattgc agcatacaca
    13741 tgattattca gaatacttta cttctttttc agtgagtcgc ccttgtgaag agacagaaac
    13801 agagagagcc tactttaatt attttttcta ttgttttttt ccaaatcaaa tctcttttcg
    13861 acaaaaacag gagattggtt ttttattttc cacaagcaaa aaccttattt gtcgacaagt
    13921 cggtcaattg atgacttact taactcaaca gtttcctctc aaccatttag aaaataaaat
    13981 accaatttat ttttattttc ttgtgttggc agttgttttt ttcgaactgt tgggtgaatc
    14041 cagcagtagt ttttctacac tttgctttcc agaagccacg tccaatcatt ctagttcttt
    14101 tatacaggaa aagaaattaa gagaaaaaat cgatacaatt ttttcaaaaa atggggaaag
    14161 aaaccaaatc agtcaatacc ttagtcaatt gatccaacac ttactacaaa cagaaacgaa
    14221 agagcagtta ctcatccatt tgcagataac caaacagttt acaggaaatt atcatcttca
    14281 aagccatttg cagcagttat ttcgcaaaga tgctgttaaa attaccgcat attcagaaca
    14341 tgctgatttg atcattacag atcagcatga gaaaatttca gatgaaacgg agactttcta
    14401 tctggataca acgcacaata cagtgttatt tggcaagtta ataaaagcgg ttcatgaact
    14461 gtatatgaaa aaaggttatg agaacaaaac aaagaggatg tgacaaaatt cttgtcacat
    14521 cctcttattc caaataaatg gtattcaatc agctaactct cggtattagc tcagatcaaa
    14581 gcgctgattt cacaacttct ttattttaat ctcttcggtt gccgccgaac aataagatca
    14641 agcgcaacag ctgcaggaat gtcgaaagcg ctgctgcaac ataagtcagt gctgctgcaa
    14701 ataatacgtg tcttgccatc ggtacttctt cttccgtcag tagtccgcct tcactcaaaa
    14761 tttggattgc tcgccgagac gcgttaaatt cgactggtaa tgtcaccaat tggaaaagta
    14821 atgctaaaga aaaagcgaaa atcccgatat tgattaacgt agagttccag ctaagcaata
    14881 cacctaccat aatcaagggg aacgaaatca tcgaaccaaa gttagctgct ggaacaagtg
    14941 ctgcacgaat cttcaatggg acataacccg aagcatcttg taccgcatgt ccgcattcat
    15001 gagctgctac acctatcgca gcaactgaag tagactgtgc agttgcttga gacaaactca
    15061 acatcttatt acctgaattg tagttatctg tgagatctcc ggcaatttgt tgaacaccga
    15121 cattatttat ctgttgactt tgtaatatat attgtgctgc ttgtgtacca gtcacattgt
    15181 ttttgcttct cacttgatcg tattttcgga aagtactatt gacgtacgct gacgcaattc
    15241 cggaaataac taatccaaga atgaccaaaa gaaatgtcgg atctaaaaaa ccatacattc
    15301 cataaccata cattttcgtt tcactccttt tcgtttactt tattttatca ttagtagtag
    15361 gaaaagaatg tgaaaagacc ttgaatattc tttaattctt tttcacaaat tccgatttca
    15421 gtttcatcgg tccaaatcct tctaccttgc aatcgatatt atgatcgcct tctactaaac
    15481 ggatgttctt gacttttgtt ccttgtttaa tggcacctga cgcacctttt actttcaagt
    15541 ctttaatcac tgtcacgcta tcgccctcta acagacggtt tccatttgca tctaatacca
    15601 ctaatccgtc ttctatgaca gtttcttgtt cttctttgtt ccattcgttc ccgcattctg
    15661 ggcaaatcaa caagcctcga tcttcatatg tgtactctga gccacattct gggcaatttg
    15721 gtaatgtcat cttctttctc ctttaaaatc tttagtgagc actattgtaa cggaaaaaga
    15781 agatcttgaa aagatacatt tgtgattttt actacaaaag gcacgttttc gaacgaagta
    15841 tcattctgtt tttctgctct tatacgattg gcatatatct tggatctctt tatagatttc
    15901 ctctacttct gctaaatctt ttgcattcgc accacttgct aatggatggc ctcctccatg
    15961 atggcgttta gccaattcat tgatgatcgg ccccttagaa cgtaaacgta cgcggtaata
    16021 ccctgaaggc tgctgaacaa aaatccccca agccagcact tcgtcaatca ctccaggaag
    16081 tgaaacgatc gaagctgtct ctgaatcatc gattccatat ttatcaagaa tttcttgcgg
    16141 aaggattatt cttcctgcac cattttcatc cacctggata ttttgataaa gataaccgga
    16201 aagtttagcg actttcatcg gcatttgttc aatctctctg ttcaaagcac ttgcatcaaa
    16261 tggataattt ctcaatatcg aagcaatctc taatgtacgg gacgtcgtgg agggatacaa
    16321 aaagcgccct gtatctccga cgattcctgc ataaagtaac cgtgcagcct taacgttcat
    16381 ctttaaagat tcaggaaaca tcaaagcaaa ttctgcaatc atctcactac agctacttgc
    16441 ttttgtattt acccacacaa gatctccata agggtcatca ttgggatgat ggtcgatttt
    16501 gatcagtttt tctgccaact gatatctttg atcactgatt ctgggtgaat tagctgtatc
    16561 agtcacgatg actagcgctc cttggtagaa gacatcttca acttcttgca tttctgctaa
    16621 aaagcgaagc ccttcaatcg tttcacctac ttgacgtatt tctttttctg ggaaactttc
    16681 ccgtaatagt tcggctaatc ctacttgtga tcctaatgca tcaggatcag ggcgcaaatg
    16741 cctgtggata atgattttat cgtatttttt tattgtatct actatttctt gctgtactgt
    16801 catttcactc ctgctttcta agaacgttcc attacttgac aaacaacgat tgctttggaa
    16861 acgatggtgt tttcaataaa cacttcgata tccagtttag cggaacgtct gccgatttcc
    16921 aatacacgtg gacgaatgtc taattcgctt tccaattgga tcagccgcaa ataatgtagg
    16981 ttcacttgtt caatcaagat atttcgtttt tggttcatca ccattgtttt ttgtgcgaca
    17041 tcagaaatga tttcgctaag tacgccaaaa gaaatggttc caacgccatt gaccatttgt
    17101 ggtgctacta cgaatttgaa cttagggttt tccaaacgat ttccttcacg gtcagtatca
    17161 atcgtatgga tatttccaga tatctgatcc gaaatcgtat ctgcaatctg cggttgtcgc
    17221 tggacaagct gcatcgcttt cattacatct tgccgggtaa tcaagccttc caatgtcaag
    17281 tcatcggaaa cgaccggcat gacttctagc ccatcccaga tcatttgatg gctaacagag
    17341 gcaatactca ttgttttctt tacactgatt ggttctttcg tcatcacccg atcgatgatc
    17401 tggtttggcg atttccctaa aacatctttt gccgtaacaa tccccatcaa acgatgatgg
    17461 cggttgacga ctggaaaacg cgaatgctgc gtttcttctg acaaacgctg ataatcagaa
    17521 atcgtatctg tctgctgcaa ataatgagtc ttttcagctg gcatatagat atcactgaca
    17581 agcatgatat cttttttgat caattggtcg cttaacgctc ggttgatcat ggttgcgact
    17641 gtaaatgtat cataagaggt gcgtaagatc ggcatttcaa gatcatcagc tagctttgca
    17701 atctcagcag tcgtattgaa tcctcctgtg atcaatactg cggcgccatc ttccaatgct
    17761 aatttttgga cttccgcccg gttgccgacg atcattagtg atcctggcgt aatatagcgt
    17821 tccatggcat gtttagtcat cgcgccgatg acgaatttat tcaagacctt gtctaatcct
    17881 gccgccccgc ctaaaacgtc cccttcaatg atcctgacga cctcgccaaa tgtcaaacgt
    17941 tcaatatgtt tttttaattt gcgttcgata cggatggtcc ctactcgttg aattgttgaa
    18001 actagtccga cattttctgc atctttgatt gcacggtacg ctgttccttc actgacattc
    18061 aattcttttg cgatgcttct tacagaaatt cgattgccaa caggtaaact ttcaatatat
    18121 tctaaaatca aatcatgttt tgtcgccatt ttctgcctac acttccagcg tttccgagac
    18181 gctcattatt tttccttcac tatcttccag taactctaca aaagattcgg gatcttgttc
    18241 aatgacaggg aaagtattgt aatggattgg aactactttc ttggcacgaa ttgtttgcgc
    18301 agcctttgct gcatcttctg gccccatcgt atagttatcg ccaatcggca agaaagcgac
    18361 atcaatatcg aattcttctg caagcaatcc tagatcactg aaataagcag tatcccctgc
    18421 atgataaatc gtttttcctt ctgcttgaat aataattccg ctaggctcgc ccatatactg
    18481 aacgataccg tctacttcat agcttgaact atgctgtgca tgtacgaatt ttaccacgcc
    18541 gaatggaaac gcatgttttc caccgatatt cataccgaat gaatctactc ctctgctgtt
    18601 cgcataatca gcaatctcaa caatactgat aattgtggct tgattttctt ttgcaatagg
    18661 aatcatatct cctatgtggt cactatgacc atgagtaatc agcaaccaat ctgtctttac
    18721 ttcttctgca gttaagtctg tcaatggatt tcctgtaata aacgggtcaa tcatcacgcg
    18781 ttggccattt tccatttcaa ttgttaaaca ggaatgtcca tgatacgtaa ttttcatatt
    18841 ttacacctcg cgttttctct gtatcttttt tattaaaaac gatttcatca cttgcacatc
    18901 aatgaaaaaa tatagctgct aaatatattt tcattggatt gatagtacag tatgtacaaa
    18961 gcaattgtaa cagataatac aggatgcacc aagtaccaag cagatataat ctcaagtttg
    19021 aggtctctgc tctgcttagc ttctcttctc gtcccttaac taattaaatc agcgtaaata
    19081 ggatggacga tcttttctaa atcggctact tttatccgaa ggcttctccc gatttcaccg
    19141 cttgacacaa ttacttcttc tttttctttt aaagaactgt ctgctaaaaa acaataatca
    19201 ggatgtgcga gttttattcc aataggggtg tttgctccgt ggggatatcc tgtatgcatt
    19261 aatacaaaat ccattccagg aaaaccaact ttacgatctt tcgtcacttg tctcgttttt
    19321 ttgtaatcta agtgatcgtt caaaggaatc aatgcgatga tcaccccagt tttgtttcct
    19381 ttcactacga gagttttaca tatcaaagct ggatcaatcc ctcttttttg tagttcttct
    19441 gtgaaagatt cttctaccac atgactaaaa tcaagtggtt gatagctgat cttttgttct
    19501 tctaaataac gttcgacttt tgtttgactc atcattgatt cactcccttt attctatcgt
    19561 ttattataaa gcgagggatg ctgtattcaa aaa
//
LOCUS       DAKCAA010000048        19507 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000048 DAKCAA010000000
VERSION     DAKCAA010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.048"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            133..3660
                     /locus_tag="OUE31_001923"
     CDS             133..3660
                     /locus_tag="OUE31_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HCU0222914.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="OUE31_001924"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="OUE31_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HCU0222915.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="OUE31_001925"
     CDS             7448..7789
                     /locus_tag="OUE31_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0222916.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="OUE31_001926"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="OUE31_001926"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HCU0222917.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="OUE31_001927"
     CDS             9146..11566
                     /locus_tag="OUE31_001927"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HCU0222918.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="OUE31_001928"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="OUE31_001928"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCU0222919.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="OUE31_001929"
     CDS             13000..13737
                     /locus_tag="OUE31_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCU0222920.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="OUE31_001930"
     CDS             13751..14566
                     /locus_tag="OUE31_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCU0222921.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="OUE31_001931"
     CDS             14579..15226
                     /locus_tag="OUE31_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCU0222922.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="OUE31_001932"
     CDS             15242..15898
                     /locus_tag="OUE31_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCU0222923.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="OUE31_001933"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="OUE31_001933"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HCU0222924.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="OUE31_001934"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="OUE31_001934"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HCU0222925.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="OUE31_001935"
     CDS             18240..18758
                     /locus_tag="OUE31_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCU0222926.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="OUE31_001936"
     CDS             18865..19365
                     /locus_tag="OUE31_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCU0222927.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
BASE COUNT         6562 a         3348 c         4185 g         5412 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaatt
//
LOCUS       DAKCAA010000049        19449 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000049 DAKCAA010000000
VERSION     DAKCAA010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.049"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(461..1090)
                     /gene="udk"
                     /locus_tag="OUE31_001937"
     CDS             complement(461..1090)
                     /gene="udk"
                     /locus_tag="OUE31_001937"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HCU0222928.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1174..1869)
                     /locus_tag="OUE31_001938"
     CDS             complement(1174..1869)
                     /locus_tag="OUE31_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HCU0222929.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1882..2598)
                     /locus_tag="OUE31_001939"
     CDS             complement(1882..2598)
                     /locus_tag="OUE31_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HCU0222930.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2928..3533
                     /locus_tag="OUE31_001940"
     CDS             2928..3533
                     /locus_tag="OUE31_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HCU0222931.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3858..4181
                     /locus_tag="OUE31_001941"
     CDS             3858..4181
                     /locus_tag="OUE31_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HCU0222932.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4363..5733
                     /locus_tag="OUE31_001942"
     CDS             4363..5733
                     /locus_tag="OUE31_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCU0222933.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5863..7164)
                     /locus_tag="OUE31_001943"
     CDS             complement(5863..7164)
                     /locus_tag="OUE31_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCU0222934.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7394..9352)
                     /locus_tag="OUE31_001944"
     CDS             complement(7394..9352)
                     /locus_tag="OUE31_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HCU0222935.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9529..9795)
                     /locus_tag="OUE31_001945"
     CDS             complement(9529..9795)
                     /locus_tag="OUE31_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCU0222936.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10305..12431)
                     /gene="pnp"
                     /locus_tag="OUE31_001946"
     CDS             complement(10305..12431)
                     /gene="pnp"
                     /locus_tag="OUE31_001946"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HCU0222937.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12619..12888)
                     /gene="rpsO"
                     /locus_tag="OUE31_001947"
     CDS             complement(12619..12888)
                     /gene="rpsO"
                     /locus_tag="OUE31_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HCU0222938.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13139..13702
                     /locus_tag="OUE31_001948"
     CDS             13139..13702
                     /locus_tag="OUE31_001948"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCU0222939.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13955..14476)
                     /locus_tag="OUE31_001949"
     CDS             complement(13955..14476)
                     /locus_tag="OUE31_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HCU0222940.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14479..15321)
                     /locus_tag="OUE31_001950"
     CDS             complement(14479..15321)
                     /locus_tag="OUE31_001950"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HCU0222941.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15314..16039)
                     /locus_tag="OUE31_001951"
     CDS             complement(15314..16039)
                     /locus_tag="OUE31_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HCU0222942.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16215..16511
                     /locus_tag="OUE31_001952"
     CDS             16215..16511
                     /locus_tag="OUE31_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222943.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17079..18671
                     /locus_tag="OUE31_001953"
     CDS             17079..18671
                     /locus_tag="OUE31_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCU0222944.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18684..19424
                     /locus_tag="OUE31_001954"
     CDS             18684..19424
                     /locus_tag="OUE31_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCU0222945.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5565 a         3991 c         3691 g         6202 t
ORIGIN      
        1 tagggggtgc gacaaaagag cttcttcaaa aaaataagtc gaaatctcac acaaattcga
       61 gaaataattt tcgtaagttt cttcttattt attgcatctg accacttctg ttacaacctc
      121 tcgttaaacg gtgttcaaaa gcttgcatct acgataataa gcccaaccca acgaaaaacg
      181 tgaggagctg ttttatttgg atgctcttat cgcttgatgc aaagacagct tttttacaac
      241 ctctacttca cggtgctcaa tcagctgacc ttcggtatta gctcaaaaaa cggtaaaata
      301 taaacagcta ttttccgttt cttcttttta atacttaggt caagatgctg ttttcacaac
      361 ctcttgttat aaataaaaaa acagttggct ggtgactgtt caaaaagcag aatccttgct
      421 tttcaaacgg tcgcagtccg ttcaactgtt tcgctgcgca ctatttatgg tttaagaaac
      481 tagctacttt tgttgtaatc aaatcaatag caacgtggtt ttctccgcct tctggaacaa
      541 tgatatccgc atagcgcttc gttggttcga taaattgatg atacatcggt ttaacaactg
      601 tcaaatattg ttcgatcacg gagtccaatg tgcgtccccg ttcttccata tcccgtttga
      661 tacgacgaat gatacgaatg tcatcatctg tatctacgta tactttgata tccatcaagt
      721 cacgcagacg ttcgtcttct aaaatcagga ttccttctag aatgatcact tcttttggtt
      781 cctgaatgat cgttgcctga cttcttgtat gcgctacata gtcatacacg ggtttttcaa
      841 tggctttata gttcagtaag tcgcctacat gctgaatcag cagatcatta tcaaaggcaa
      901 atgggtgatc gtaatttgtg ttcaatcgtt cttcaaaact caaatggctc tgatccttgt
      961 aataagaatc ttgttcaagc atcatgatgg aatggtccgg gaagttgttg aaaatcgcac
     1021 ggctgacact tgtctttccg cttccggatc cacccgtcac accaatgata attggcttgc
     1081 tttttgtcat tgactaaaac ctctttcgta tccgtttttt cattctaatc tattatagcg
     1141 aaaaaacacg aaaatgctat atttttctga aaattaatcc ttttcaattt ccaataatga
     1201 ataaagttcc tctaatgaat cgattcgata agtaggctgg atttcttcga tttctggtaa
     1261 tttatttcta ttgaaccaaa tcgtatcgat ccctgccata tttcctcctt tgatatcaga
     1321 agtcaaagaa tcaccaatga tcacagtttg ctttttatca aaattaggaa tgtgggaaaa
     1381 gacatgatca aaaaattctt tcatcggctt ttgcgctccg acagcttctg agacaaagat
     1441 atccttgaag taatcaagca ttcctgcatc tgttaatcgc cgatgttgcg tgtgcgacac
     1501 accgttcgtc acaatataaa gatcagcatg cggatggacc tttttcagga tttctagact
     1561 tcctggaaca agatcatgac cttggttcaa gtagtggcgg tagcgttttt ccatttgatc
     1621 actatctact gttttcccaa attgctggaa aagtaaccca aaacgactgc ctattatttc
     1681 ttctcgtgat agtctgcctt tttcaaactc ctgccataaa tgatgattca aagccttata
     1741 gctggtttcg atttctggtg tcaatgtgat tccttgttct gcaaacaaag cacttaaagc
     1801 attggcttca gttaattgaa aatctaacaa tgtatcatct acatcgaaca ataaagtttt
     1861 atatttcatc tttttgacct cctatttaaa ataaatactt aactttttca tctctgctaa
     1921 tgtcaacgat cgatactcgc ctactcctag ctgttcatct aattccaatg gtcccatgct
     1981 tagccgtttc aatgcggtca ctttctttcc ttgggctaag aacatctttt tgacttgatg
     2041 gaattttcct tcttggatcg tcaataaaac cgtactttgg tgcttgtctg ctttgagtat
     2101 ttttaaatca gccggcttac attgataccc atcagcgaat acgattccat tttcaaatgc
     2161 tgttacgtct gccggtgtca ccctttcgtt cacaactact tgataagtct ttgaaacctt
     2221 tttttctgga agtagcattt catatcccaa ttgtccattc gaagtgatca gcaatagtcc
     2281 tgttgtatct ctatctagtc ttcccactgg atataatggt tggaaacgat cggcacttgc
     2341 aatcagatcg attactgtcg tcttttctgg atctgataca gctgtaacag ctttttcagg
     2401 tttattgaga agataatagg actcatttgt ttctaagtgt tcacctgcta cttcgatttg
     2461 atgcagtaaa ctatctacat ttcgattttg tcgaaattcg actgtgccat ctatcatcac
     2521 ttgcttcaaa gcaaacagcc gcttcatttc cttgcgtgtc gtttctaatt tttcttctat
     2581 taatttatct aaacgcatgc tgtttccttt cttattacta ctaattaatt ataccttgaa
     2641 tattcttgct tgcaaataca tcatcatagt tattccttga cttaattaac agttcacgtt
     2701 acggttaaat agtaaagtga attggatttc tcatacacag cgtaatgacc tggtggagaa
     2761 aagttgaatc ctgactttct aaggggagat gcgcgcatct ctccttttgc gcttttttaa
     2821 gcgccctgcc ttcgatgatg tgcacgagat tagcctttag aattcactta aataaaatct
     2881 gtccgttacc aaagcagaca gtcacatttt aaggaggaat tttggttatg tcagtatcat
     2941 tagaagtaag taaaagagaa gtacgtcccc gttcattaag aaacaaactt cgtcacgaag
     3001 ggaaagttcc agctgttgtt tatgggtata aagtagaaag tacccctatc tcattcgatg
     3061 gtttgacact aagcaaattg ttgcgtgaac atggagcgaa cacagtcatc acgatggaca
     3121 tcgatggaca aaaagtcaat acattggttc acaagatcca aacgaacact tttaccaatc
     3181 atttcgaaca tgcagaattt ctatctgtaa acatgtcgga agaaacagaa gtcgaaacag
     3241 aagtcgttct tgttggcgaa tcagtgggtg ctaaatctgg tggagtgtta gctcaaaact
     3301 tgtatacagt agtcgtatct gctacaccag acaaattgcc tgaacgaatt gaagttgacg
     3361 tgacaaactt ggaattaggt gattctatta cagtagccga tcttccaaaa aacgacgatt
     3421 acaaattcgt gaccgacagt gaagagcaaa tcgctgctgt agtcgctcaa agtgaagaag
     3481 aaagcacagg tgaaggtggc gaaccagaag tgatcggttc aacagaagaa taatactgaa
     3541 acaatcaggt ggtgttagaa gcggcgggtc agcagctttt aacacgcctt ttttatttct
     3601 aatcgtttat tttcatatgg ggcttccact tttgtaaatg gctttacaaa cgaaaaatcc
     3661 taatttacca agcttttcct cgcatacttt tatcgtacct ttataaaaat ttatactttg
     3721 aaaaaaagta ttcaattatt gttgcatttt tcctgattct ttattagaat gaaccctcgt
     3781 tgaagtaagt atttctagtt tatcctagga ttaattataa aaataaaaca ttcgttgatt
     3841 cgaaggaggt taaacagatg tttgaaagtt ttgatagcag ccgcaaccgt tacgcttcag
     3901 ttggtgtcgt atcaagtttg ccagatgaat tgattgacag tatatggttt attattgacc
     3961 tagatcttaa gggagtcatt ccattagaaa atatattaac ctttgatttg atcgaaaatc
     4021 gtggaaaagt gacgatgcat ttttctcaag caggaagcaa tgtggaaatg gatattgatt
     4081 tgccgtttgc ctattcgaac caatttcctg ctcaagtata cgcctatgat gacggtacga
     4141 gagaaacgat ccttttacca agtgagatta gacaatatta aggtgataga taaacgtgga
     4201 tgtcccttat tttacagacc aggccaagtt gttgattctt tgactcaatt cttggcttct
     4261 ttttatggag tttcataaat tatcattgat ttctaattgg tattctcagg ataaacgcta
     4321 tatactacta actaaatttt aaagatataa ggagtttaaa agatgcgcga tttaacaaaa
     4381 ggaagccccg ctaaactgat tttgatgttc actgttcctt tactgatcgg aaatgttttt
     4441 cagcagttct acaatatgat cgatatgatc atcgtgggtc agacgctagg taaaaatgcg
     4501 ctggcagcgg ttggtgcaac tggaagcctg acatttttga tcattggctt tgcccaaggt
     4561 ttaacagctg gtttagccat tattaccgca caacgttacg gtgcaaaaga ttatcggggt
     4621 ctgaagaaaa gttttgctgc tagtgttgtc attagtcttg tcgtcactgt gattttaact
     4681 gtcctaagtc tcctgtttat tcgtccgatg cttcaattga tgcaaactcc tcctgaaata
     4741 cttgatcaag cacaaacatt tatttcaatt attttattag ggatctttgc atcagtcagt
     4801 ttcaatttgc tttctaatgt cattcgcgca cttggtgaca gccgcacacc actattcttt
     4861 ctgatcattg cggtcatcat caacgtcgta cttgatttga tctttattat ctattttggc
     4921 atgggtgtgg aaggtgcagc tattgctaca gtaatcgcac aagtttcttc cagcgtactg
     4981 tgtctagtgt atatcaagaa aaaaatgcct ttgttacagt tacgcaaaaa agatttcaaa
     5041 tttgaaaaag aagagtttgc tgtacaccta aatgctgctt tgccaatggc gtttcaatct
     5101 tcgatcatcg ctgttggtgc tatcgtgtta caagcagcac taaatagtct agggacagat
     5161 gtcgtagctg ctcaagccgc tgctggtcgt atcgaccaat ttgcaaatca gccgatgatg
     5221 tcatttggta ttgcaatggc aactttcact gcacaaaact atggtgcgaa agaatatggc
     5281 cgaatcttgc aaggggtacg tcaaacttta ctgatgagtg tcggatttag tctcttagca
     5341 ggtgctatcg tcattttctt cggtcatttc tttgttcaat tgtttgttag cccatcagaa
     5401 acacgtgtat ttgaattagc acaaacctac ttcaatatca atgggtctct ttactggatc
     5461 ttagcagtcc tgttcatttt acgctacaca cttcaagggc ttggacaaag caagatccct
     5521 acgatcgccg gtatgatgga attgcttatg cgttcttttg cagctatcgt tcttacagga
     5581 atgtggggat acccaggagc agcagcagct tctcctttag cttggatcgg ttctgttgcc
     5641 gtgttgcttt actcttatat gcgttcgatg aaacaattga aacacatggg tgaagaggaa
     5701 catttcacat tagaacatgc agaagcaaga tagccttgat taaaagaaat cgttgcggct
     5761 aaaaatgaaa acttttattg aaaatatctt cttcgtttac cgaaaacagg ttttttagat
     5821 aacaaaaagg ctgtgacaaa aaatgtcaca gccttttttc ttttattcta tttttctttc
     5881 cgtggactct actttgaaat aatcgatatg tgcatgctgg tattctaata ccgtgaaacg
     5941 gaatgatgca atctcaatga ttgttcctgc ttttatttct ttatatcggc tagaagcaaa
     6001 gcccgcaagt gtagtaaaat tcgtttcttc aaactctgga atctctacat gaaaataacg
     6061 ctggaaatca tctaatgtta gtttgccgga gatgatataa gagccatctg actgttccgc
     6121 tatcaatgct tcgtccaaat ctgtctcatc tcggatttcc ccgacgattt cttctaaaat
     6181 atcttcaatc gtcactaagc cgcttgtccc tccgtattca tcttttaaga tagcaatatg
     6241 ctttcccttt tttcgcatga tcgtcaataa tttttttata gggatcgttt cagttgttac
     6301 gatcggctct tcaatcaact gttctactgt cagctggtca tctttataag attgcttgat
     6361 caaatctggc aaggtgacat aacctaaaac attgtctttt gattctaaga taaccggata
     6421 gcgagtatgt ccttgttcaa tcgaagcttt tatcgcttct ttgacggttt ctgaagcttc
     6481 gaatacttgc atggacgtac ggtctacttg tatatctttt gccaaggtat catcaaattc
     6541 aaacacgttt tccaaataat gatattcttc tttggtcaac tctccttttt cataagaatt
     6601 caatgcgact aatgtcagct cttcttgaga caatgtctct tctccttcag atacgagacg
     6661 cacacctaat agcttcccta gccctgcagc tgaatgattc aatacccaaa taaaaggaaa
     6721 cattacttta taaaaataat gaagtggttt aactacgaac aagacgacct tctccgtatt
     6781 gacgatacta tagctcttag gaagcagttc gccaataacc acatcgatat acgtaactaa
     6841 aataaatccc agcgccacag agattgtact gctaatagcc gaactaaaag gtagtttacc
     6901 gatcactggt tctagtaaag ccgcgacaga tccttcaccg acccacccga tgatcaaacc
     6961 ggttagcgta attcctaatt gactagctga taaatagtta tctaaatggt gtgtaacatg
     7021 aagagctagc ttggcgttct ttacattttc cttttctagt tgttccaatc ttgatcgtct
     7081 gattttcact aaagcaaatt cacttgctac aaaaaatgaa gtaattgcaa tcatcaaaaa
     7141 taaaataatg aaattgataa ccatattctc ccgcctttct ctttttctat tgtacccttt
     7201 ttctacaaaa agattgaaaa taatgcgtat tcatatttag gaataaaaaa ggagatgcgg
     7261 catttttcag ccacatctcc ttataacttc aaaatcattg cgttacttgt tgctaaacag
     7321 ctttttcatg acctctgata aacggtgttc aagtagctga cattcgacat tagttcaggt
     7381 caaagcgcta ctttcacaac cgctctttca accatgtttt ccgagtattt ccaatgataa
     7441 gcggaacagt ttcatgtttt acttcgctgt actctagccc aaaccatgtt tctggcgagg
     7501 tagcgatttt tttgattgcc agttttgcct gcatgatttg acgttgccat tttcctagag
     7561 ttgtcacatt ggaaactact tcatcaatca ggacaaattg gaaatcgcca acttctcgcc
     7621 ctggtgtcag agagtatctt tgtggctgtt ttggcaaacg gccttgtttc atcaaatcat
     7681 ggatgacttg gcgaacatat acgttgattt cctgttggac cctgaaacct aagaacagat
     7741 tcacttggac aataaaatca gtgtccatca tatctacttg atattctttc gtatatggct
     7801 catccgtcac ttccacatga acaaaccaat agactcgtgc tcttttaggc cgtttatcta
     7861 aaatcgaata gatgaactgt cggccaactt tatcttcagc catatcagga accaagaaga
     7921 ccacatttgt ctgatagatt ggtaaagaag tatcatcacg taattctcta agctgcggga
     7981 tataatctct caaagacaca tcctcggttg acgattcgcg aataatgttc ccttgttccc
     8041 aaataaacat cacgactaag atgatcaaac caatcagaac ggctacaaaa ccgcctcgga
     8101 agaatttgac aacacttgag ataaagaaaa cgacttctat cgcaccgaag aaaaaggtaa
     8161 ctaaatatgc aagccaacga gaatgcccat tttggataag ataaaagtaa agcagtgctg
     8221 ttgtcatcaa catcgtcaca gtgatcgata gaccgtaagc agcttccata tgatgagacg
     8281 ttcggaatgt gacaaccact agagaacagg cgatccataa aatcagattg actgctggga
     8341 tatacatttg cccgatactg ttcccaggat acatgatctt taaccgaggc agcagtttca
     8401 acttgattgc ttctgaaact agcgtaaacg aacctgtaat caatgcttgc gaagcaatga
     8461 ctgcagcgac tgttgcaaaa gcaacgccga tcacgatcca actttgaggc atcatttgga
     8521 agaatggatt caggttcttg atttgctgtg cttcagggtt ttgataaaca ttcaacaacc
     8581 acgcagcctg cccaaaataa ttgataacca aacaaatttt gacgtaaggc cagctcagac
     8641 gaatatttcg tttgccgaca tgtccaagat cggaataaag cgcctctgca cctgtcgtag
     8701 ccaggaaaat atttccaaga atgaacaagc ctaatttgtt atctgcacta aaaagcagct
     8761 ggatagcata ataaggattc agtgcacgga taactgtcca gtcttgactg aagttcatta
     8821 atcccattac gcctaaaaaa gtaaaccaag cgaacatgat tggtccgaat gcttttccga
     8881 caatatctgt accaaagcgt tggaccatga ataaaacaaa aataataact aaagtgataa
     8941 tgacgatcac gttctggtta ttaccgaacc ggtcaaaaaa ctgcggaatt cctcgcaagc
     9001 cttcaatcgc agtcgttacc gtcacagcag gggtcaatac cccatctgct agtaaggcag
     9061 ctcctccgat cattgcagga atgatcaaat atttcccacc ttttcggaca agtgtgtaga
     9121 gtgagaaaat tccaccttca ccatggttat ctgcattcaa tgcaatcacg acatatttga
     9181 ttgttgtcag tagagtcaat gtccaaaaaa tcaatgagac tgatccgata acaaaatcag
     9241 gattgattcc tgacaatccg ccattatctt caacaatcga tttcataacg taaagcggac
     9301 ttgtcccgat gtctccgtag acgactccca tcgctacaag caggccagcc attgatatct
     9361 ttttggtatt gtgcgttgtt gccacgtttt tccctcattt cttgttatat ggatatcctt
     9421 taggtaagct tgaatgatag atgatattct tatccatgat acccgctttc ctaaattgct
     9481 tctaattatc caagtaacac actgaagtgt caacttattt gaataaaatt attctttctt
     9541 tggacgttct ctgatacgtc ttgccacaaa tgaataaaga gcaaggcaaa aaattgcacc
     9601 caataatgct ggtatcaaat aaaaaccgcc gagttccggt cccagtggtc ctagtaaaaa
     9661 ttcgccgagc caactaccta aaaaaccgat aatgatattt ccagatacgc ctcccgggac
     9721 ttcctttcct aaaattgcgc cagctatcaa acctaatata ccgccgataa ataacgacca
     9781 taaaaaattc agcatctcct ttccctcctt tatccatatt tctcactttt attttacgct
     9841 ttattcagaa ggactccaaa aatatgcgcc aagaaactcc agaaaaaaag aagttgtaac
     9901 aaaagtgttc agcttatttc cgtagaagct gcttctggaa caccgtgaat cagaggttgt
     9961 gaaatcagcg gtttgacctg agtattagag aaacaaacgg aaaaatagtt cctcatattt
    10021 tgccgttttt tgagctaata tcgagggaca gctgattgaa catcgtttat tggagaggtt
    10081 gtaaaaaagc tgttctgcat caagtaataa gaacagccaa gtaaaaacag ctcctaatgt
    10141 ttttaacttg gctggactta ttaccgcaga tgcaagcttt tgaacaccgt ttattcgaaa
    10201 aaaaaggact gtgacacggc ttttgtcaca gtcccctttt ttcgaataat tattgtcccc
    10261 ctgtcacctt cacgatcaca agtacattat tcctatgaat taaattattt ttcttcattt
    10321 ttcgttgaac catcttcgtt caacattgct tttcttgaca gatttacgcg tccttgttta
    10381 tcgatttcag ttactttcac aaggatctca tcacctagtt taacaacatc ttcgacttta
    10441 ttgacacgat cgtttgctaa ttgggaaata tggacaagtc catcttttcc tttgatcaag
    10501 ttgacgaatg caccgaattt ttcgatacgg acaactttcc ctagataaac ttcaccaact
    10561 ttgacttctt tggtcaaatc ttcgatgatc ttgatagctt ttttgatcat ttctgcatca
    10621 gctgaagcaa tacttacttt tccatcttga tcgatatcga ttttcacacc agtttcatcg
    10681 atgattccgt tgatcgtatc gccgccttta ccgataacat ctttgatttt agcaggttcg
    10741 atctggatca tttcgatttt tggtgcatat tggcttaatt cttcacgtgg agcagcaatc
    10801 gttgaagtca attcttctaa gatttccata cgtgcttgtt ttgcttgagt taatgcttca
    10861 gttaggattt gttctgtgat tccttgaatc ttgatatcca tctgtaaagc agtgatacca
    10921 tcttttgtac cggcaacttt aaagtccata tcgccaagat gatcttccag cccttggata
    10981 tcagttagga tcgtatagtt ttcaccatca gaaacaagtc ccatcgcaat accggcgact
    11041 ggcgctttga ttggtacacc tgcatccatc aatgctaatg tgccagcaca gatacttgct
    11101 tgggaagaag aaccatttga ttccaatact tctgctacta aacggatcgt ataaggaaat
    11161 tcttcttctg aagggattac ttgtgctaac gcacgttcac ctaatgcgcc atgtccgatt
    11221 tcccgacgcc ctggagagcc tgcacgtcct gtagaaccaa cagaaaattg agggaaattg
    11281 tagtggtgga tgaatcgttt gctgacttcc acccctaaac catcaatgat ttggtgctct
    11341 cctagaggtg cgagtgtaca agctgataaa gcttgtgttt gtcctcgtgt gaacaaacct
    11401 gatccatgta cacgtggcaa taagctgacc tctgatgaca atggacggat ttcatccaat
    11461 ttacgcccgt caggacggat cttatcgatg gtgatcaatt cacgtacgac atctttttca
    11521 agatcttctg tgatttgttt aacttctttc aacaagtgat cttcatcttc atgacctgca
    11581 aatttctcag cataagcttc gcggatatcg atcttcacct gctcgatatt atcttcgcga
    11641 gcaagttttt cttcagtcat tactgctgct ttcattgtag cgtaagaagc atcaaagatt
    11701 tcttttttca atacttcatc aacttgcagt aaagtcactt ccattttttc tttccctact
    11761 gcttgaacga tttcttcttg gaaagcaact aactctttga tagcgtcaaa accaaacagc
    11821 aatgcaccaa gcatgtcttc ttctgaaact tctttcgcgc cgctttcaac catattgatg
    11881 gcttgtttcg ttccggcaac agtcaattcg atatctgttt gttctgcttg ttctactgtt
    11941 ggattcaaga cgtactcgcc atttacacga ccaacttcta cgcctgcgat tgggccgtca
    12001 aatgggatat ctgagattga tagtgctaaa gaagaaccta gcattgctgc catagctggc
    12061 gagcagtctg tttctacact catcacgatg ttcgttactt ggacttcatt acggaagcct
    12121 tctgcaaaca tcgggcgaat tggacggtcg atcaaacggg cagtcaatgt tgcttccgta
    12181 cttggacggc cttctcgttt gatgaaacct ccagggattt tccctgctgc atacattttt
    12241 tcttcataat tgatcgttaa tgggaaaaag tctgtatctt ttgcttcttt agaggccaca
    12301 gctgcactta agactactgt atctccataa cggactaaaa cggctccgtt tgcttgtttt
    12361 gctagctgac cgacttcgat ttgtaaggga cggccgcccc atgtcgtttt gaatacttgt
    12421 ttttctgaca taacttctcc ttttccttct cgtgaaagca agacgctact aaacaaatga
    12481 aaactgccga aagccgtctt ttgagcagct ttcatttggt tagtaggagt ccatctagct
    12541 tgatcacgga attttactta attgatatac gagtaaaaaa agtgagattc atgtgaatcc
    12601 cactcttttt gactaaaatt aacgacgcaa gcctaaacgt ttgatcaatt cgcggtaacg
    12661 ttgaacgtca gttttacgta agtaagctaa caagttacgg cggtgaccaa cttttttcat
    12721 taggccgcgg tatgaatgat ggtctttttt gtgcacgcgt gcatgttcat tcaagtggtt
    12781 gatttcttca gttaatacag cgatttgtac ttctggagaa ccagtatccc cttcatggcg
    12841 agcgtattcg ttgatgattt cattcttgcg ttcttttgaa attgccattt ctttcacctc
    12901 tttcgattat tcccctgcga ctgagtaaaa cgttggtgat tcgcttaacc aagtggcagg
    12961 tcatgtgcct agagcacaca gctatacttt acctgaaacc gggttgaaaa tcaagtagtt
    13021 aatcattaag aaaaggtagt tttcaaacaa tcttactact acttttccat ttttgtggta
    13081 aactataatg cgaaaataga cttgaaacac agtcttttaa gaaaggggta catattccat
    13141 gattacaatg gatgatatca ttcgtgaagg aaatccgacc ttacgcgaag ttgcaaaaga
    13201 agtttctctt ccattaagcg aagaagatat ctctttagga aaagagatgc ttgagttctt
    13261 aaaaaacagc caagatccaa tcaaagctga agaactacac ttacgaggcg gtgttggctt
    13321 agctgctcct caattagata tttctaaaag aatcattgct gttcacgtac caagtcctga
    13381 cccagaggca gatggacctt ctctaagtac tgttatgtat aatcctaaaa ttttgagcca
    13441 ttctgttcaa gatgcttgtt taggggaagg tgaaggctgt ttatctgttg atcgagaagt
    13501 accaggatat gttgttcgcc atgccaaaat cactgtgtct tattatgata tgaatggtga
    13561 aaaacacaag attcgtttga agaattatga atcgatcgtc gttcaacatg aaatcgacca
    13621 tatcaacggt gtgatgttct atgaccacat caacgatcaa aatccatttg cactaaaaga
    13681 aggcgtattg gtgatcgagt agagaattgg caggttcctt cgatactatg ctacaagaaa
    13741 gctttataaa aaaggggagt gctcaaaagc tgcacttccc ttttttatgt ttctccacta
    13801 atcgaaattt agatagacat ctagaaatcg caattccaaa aaattctgtg tattggatac
    13861 gcatcttttc ttattttttc ttatttcttc catatgggtg tttatctcag agatgataga
    13921 atagtttcta ggataaaaag tagcagctac gatgttatcc ttcgtagagg attcctgctt
    13981 cagctagttt ttgtttgatg tttttcagca tatgcttttc tgggtagcgg atcgtatgca
    14041 gatggatgcc gcctgttaat tcggataaca aagtagcatt acttttttga taacgtctca
    14101 taaaggaatc gatatcttgt ggcgttttga tgtgcaaagt tcctgctaac tcaccgtaaa
    14161 ggggatgttc cacaattaca tcaatgattt caccaccatt ttcaacgatt agtctcagtt
    14221 cttcttctgt ttgatctttt ccatgctgga cagcgatttt actgatgtgc ccagtattgg
    14281 tttcttctgt ttcgaggata taacctcttg ctgttgccac gatactttta cctgcagctc
    14341 gtagtaaagc aatatcgcct acaatgatct gacggctgac tccaaaagtt ttcgcaaact
    14401 tgctagcact cactggtttt tctgtatttg ccaaggtttg catgatttgt tttcgccgtg
    14461 tctctccttc gatcacactt attcctcctt cattttgttt tggtattcgc gcgagtgttt
    14521 catcaaatca acatacgtgt ctgttattgt ttccttatat cccttatttt tcagcagact
    14581 aacaacttta tccaatactt gctgctctct ttttgcatca taaactgctt ggttttcttc
    14641 ttttttcact tgtcctattt tagttaccgt atccattctt ttttctaata aagcaaccaa
    14701 ctctcgatcg atcatatcga tcttatgacg taatgtttca agagactctt ctgttagttc
    14761 ttcctctact gtcttgatga tacgagcagg atttcctgca atcactacat tgtcgggaaa
    14821 agatttggtc acaaccgaac ctgcgccgac tactacgttg tcccctagag tgacacccgg
    14881 cgtgacgata actcctccgc ctaaccaaac attattaccg attttaatgg gttttgcgta
    14941 ctccagaccg ctgttacgtt tcactggatg tagtggatgc gtcgccgtgt aaagctggac
    15001 attcggagcg aacatgcagt tatcaccgat ttcaatcgtg ctgacatcta aaaatgtaca
    15061 attgaaattt gcataaaaat tctccccaac aaatatatta tatccgtaat caaaattgat
    15121 aactggctcc atatagattt ttttccctgt acggccaaaa gtctctttca acaattggga
    15181 tcgcagttcc gctgattctg cttggttgat gatttggctt tgacttcttg caaacatacg
    15241 gtcggcaacc agctcaggat cattggcaaa ataaagctcg cctgcaatca ttttttcttt
    15301 ttcggttttg aattcagtca taatctgctc ctaattcttg tatttttttg aaaacaaccg
    15361 ctccgtcttc ttgaataaac gtataaggct ccgctaaata aacaggcgtt tgattgatta
    15421 ctaagatttt ggctgacggc tggcgaaact gtaccagatc acaaaacgga tgaacttgaa
    15481 aactcgttcc aacaatgacg atcagctctg cttggctgac ggcataagcc gcctgctcca
    15541 tgactccatc ttgaaaccct tcaccatata acacgatgtc tgggcgtatt tgtcctccgc
    15601 atgcttgatg tttgtcgctg tgaagatatt ctttccagtc taccgtttgt tgacattttc
    15661 gacaatgaca ttgatacaga ctcccatgaa aattgacgag ttgcgggctt ttagcctttg
    15721 cgtgcaaacc gtcgatgttt tgggaaacaa cccaaacatt tttttctttc gctagatgtg
    15781 ctatttccaa atgaatgata ttgggttttg cttcaggatg ataaatcttt ttgacaaatt
    15841 gatagaattt atccggttca ttcaccattg cttgatgact cagcaagtat tccggctgct
    15901 ccatcccgtg gtagattcct gacaaagatc gatagtctgg cactccagaa ggtgtggata
    15961 cccctgcacc ggtcaaaaat gtaatttgct gataagctaa tatctctttt gctgcttcgt
    16021 ctactgttaa ttgtttcatg ttttgtcacc tcactttcca ttatagccca tactcgaaca
    16081 aatttattgt tgaaaagtca gaaaaatggg aataaaaaag tgttatgggc atttgagcaa
    16141 tttatcacaa tgttcactga caaaagaatg aaaacgtgtt acaatactgc tgtataaaag
    16201 tgaggtgaat cgatatgtta ccattcttta tttattgggg cgttattctg gcttgtatcg
    16261 cctggttagc gttaagcgtt tatttctctg ttttttatct tgtacgcaaa gaaaatggaa
    16321 atctttgggc ttttgcttta ttcaacgtga ttgccgcaat tgttttagcc attacattag
    16381 ccgtatatcg aacatggggc tggggaatca cccaatactc aagtttgatt tatctaatat
    16441 tagccattta tggcgtcgtt gttcttttgc aagcgatcct aggacgtgag ccaaagaaag
    16501 cggcagctta aatgatcgag atggaactgg acacaggaaa ttttctgttc tagttctttt
    16561 tttattgtat tacatacatt tttgtgtata attatactat cgtttgcaat ggatagatga
    16621 ttcacatttt gattgttttt tcggtaaaag taaagatttc tatatttatc agtatttttt
    16681 caaaaaccag cagttataga ttgacaaagc ctctcgagta tcgtaaactt tttttgtata
    16741 aataactgaa tacgagatgc ctcaatcaat gaggtagagg tcgcgagaat cattaaccct
    16801 gtggagtgaa gcaaacatgg agaagcagga atagggagga tcgccgaaat gtgcactttt
    16861 ttgcttggag tgtatgttgg gacgcaagtt aagagcttgc ggactgtctt agcagtgatg
    16921 ctaagttgcg ctatgttttg tgagaggttt atcaccttat ggaattttag cggccttttt
    16981 atatctataa atcggtcgct ttttattttt tcagataaag ctttaccgca tttcatctag
    17041 accgctcgtg tatcatataa tcagaaaggg agaaaaaaat gaaaaaaaat atggtttcag
    17101 ttgccgtact atttgctttt gtcttctcac tattcagtgt gggatctctg gcaaatgcag
    17161 atgaaaaaac accgagcgat gagtttcgcg taggtatgga ggctgggtat gcacccttca
    17221 actggtctca acaaacagat gagaataatg ccttgccaat tcaaggccaa aatagttacg
    17281 ccggcggtta tgatgttcaa atcgctaaaa aagtagcaga tggtttaggg aaaaaattag
    17341 tcatcgtcca aacgaaatgg gatggtctgg ctcctgccct tcaatcaggc aagatcgacg
    17401 cgatcatcgc cggaatgagc cctactgctg aacgacgaaa agaaattgat tttaccgatc
    17461 cttattacga atcacaatta gtagtagtag ttcaaaaaga tagcaaatat gcaaaagcaa
    17521 aaagtttagc agatctttct ggagcaaaga tcactgctca gttaaataca ttccactata
    17581 ctgtgatcga tcagatacca gatgtgcaga aacaacaagc aatggataat ttctcagcaa
    17641 tgagaacagc tttagcttct ggaatgatcg atggttatgt cagcgaacgt ccggaaggtg
    17701 taacggcaac tagtgtgaac aaagacttgg aaatgcttga attcagcggt gcagatggct
    17761 tccagacaaa cccggaagat gttcagattt ctgttggtat gcgtaaaggc gacccggata
    17821 tccaaaaagt aaaccagatt ctttctggca tctctaacga tgaacgaacc aaaattatgg
    17881 accaagcagt caaagatcag cctgctgcaa ctgatagtga agaaaaacct ggcatcattt
    17941 ctgatttcac tacgatttgg aaacaatacg gcaatatgtt cttacgaggt gctggactta
    18001 ccttgttcat cgcattgatc gggacagttg tcggtactac acttggatta ctgattggtg
    18061 tcttccgttc ggtacctgaa tcaggaaatg cactgactcg cttcttccaa aaaatcggaa
    18121 atgcacttct ttctatctat gtcgaagtat tccgcggaac accgatgatg gtacaagcaa
    18181 tggtcatctt ctacggtctg gcactcgctt ttggcatttc attgaaccga acgattgccg
    18241 ctttgtttat tgtctctctc aatactggag cttacatgac agagatcgtt cgtgggggga
    18301 tttttgcagt agatgaaggg cagttcgaag ctgcgcaagc cattggtatg acccatggcc
    18361 aaacgatgag aaaagttgtt attccacaag ttttacggaa tatcttgcca gcaacaggaa
    18421 atgagtttgt tatcaatatc aaagatacag cagttttaag tgtaatcggc gtagctgatt
    18481 tgttcttcca aggaaactct gcttccggtg cgaatttcca attcttccaa acatttacga
    18541 tcgtcgggat catctactta gtcatgacct ttacgatcac cagaatcctg cgggcggtag
    18601 aaaagaaaat cgatggtcct tcagcttata ccaagcttga agaaatcgac aattcaaatt
    18661 tgcaggaata aggaggaaga atcatgaatg aaaaaattat tgaaatcaaa catctaagaa
    18721 aaagcttcgg tgaaaatgaa gtattgaaag atatcagcgt aacagtcaat aaaggtgaag
    18781 ttgtgacgat catcggttct tccggttctg gtaaatctac tttcttgcgc tgtatcaatt
    18841 tactggaaaa accaacaggc ggcgagatca tttataatgg agaaaatgta ttagctccta
    18901 aatataattt acctaaatat cgaacgaatc taggtatggt tttccaatcc ttcaacctgt
    18961 tcaacaatat gaatgtcttg gaaaactgta tgtctggtca aacaactgtc ctgaaacgag
    19021 ataaagaaac tgccaaaaaa gtagcaatcg aaaatctgga aaaagttggt atggatcgtt
    19081 atatcgaagc caaaccagca caattatctg gtggacagaa acagcgtgtc gcaattgctc
    19141 gggcattatc aatgaatcca gatgtattgc tattcgacga acctacttcg gcgttagacc
    19201 ctgaaatggt tggcgaagtg cttaatacga tcaaagactt agcacatact ggcttgacaa
    19261 tgcttatcgt gacgcatgag atggaatttg caaaagatgt atctgaccgt gtcattttta
    19321 tggataaagg tgtgattgca gaagaaggta caccagaaga tatctttgtc catccgaaag
    19381 aagaacgtac aaaagaattc ctttcacgta ttttaaatgc ttaggatcaa tagctgattg
    19441 ggacaaaga
//
LOCUS       DAKCAA010000050        18896 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000050 DAKCAA010000000
VERSION     DAKCAA010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.050"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(22..252)
                     /locus_tag="OUE31_001955"
     CDS             complement(22..252)
                     /locus_tag="OUE31_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222946.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(688..1254)
                     /locus_tag="OUE31_001956"
     CDS             complement(688..1254)
                     /locus_tag="OUE31_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCU0222947.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1254..2210)
                     /locus_tag="OUE31_001957"
     CDS             complement(1254..2210)
                     /locus_tag="OUE31_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HCU0222948.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2210..2866)
                     /locus_tag="OUE31_001958"
     CDS             complement(2210..2866)
                     /locus_tag="OUE31_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCU0222949.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3236..5254
                     /locus_tag="OUE31_001959"
     CDS             3236..5254
                     /locus_tag="OUE31_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCU0222950.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5324..5530
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5681..8095
                     /locus_tag="OUE31_001960"
     CDS             5681..8095
                     /locus_tag="OUE31_001960"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HCU0222951.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8443..9996
                     /locus_tag="OUE31_001961"
     CDS             8443..9996
                     /locus_tag="OUE31_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCU0222952.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10377..12161)
                     /locus_tag="OUE31_001962"
     CDS             complement(10377..12161)
                     /locus_tag="OUE31_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222953.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12176..13897)
                     /locus_tag="OUE31_001963"
     CDS             complement(12176..13897)
                     /locus_tag="OUE31_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0222954.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13997..14758
                     /locus_tag="OUE31_001964"
     CDS             13997..14758
                     /locus_tag="OUE31_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCU0222955.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15725..15993
                     /locus_tag="OUE31_001965"
                     /pseudo
     CDS             15725..15993
                     /locus_tag="OUE31_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16665..>18896
                     /locus_tag="OUE31_001966"
     CDS             16665..>18896
                     /locus_tag="OUE31_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222956.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6205 a         3353 c         3786 g         5552 t
ORIGIN      
        1 tctcattaaa aagcataacc attactccga tctgttttta aaattagttt ctacctctaa
       61 tatatatcga gtttttattt tgccttcaga gaatactgtt tctttttttg cagttacagg
      121 ttgtttattt tcggaaaaag ctaatatagc taagattgaa acatccatct ggaatttatc
      181 ttttttactg ctttgatcat aaaagtctgc atattcatca ctgatatttt ttctaataaa
      241 ttcttccatc ataaaaatca cctcaaaacg attatacgaa cttacgttct tgttgtaaag
      301 cgatatttga ggggcaaaaa aggggcataa tttgactgat attaagttag ctattgatat
      361 atgaatgaca tacaaaaata taaaatcttt taaaaatgct tatatatcaa tgtttttgcc
      421 attcttttat atatctgtta tatgtcaaaa aaatgtgttc aatttcaatt tgtatttgaa
      481 taaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag
      541 cttctcatgt ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt
      601 gaataaagag gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac
      661 atatcattta tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg
      721 cggctggttc ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag
      781 tttggaacaa aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta
      841 gacgacaagg atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt
      901 gcgtgtagtc tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt
      961 gaaaatccct gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc
     1021 ttgtagaaac aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc
     1081 atcgattgct tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc
     1141 tgctagaaaa accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg
     1201 ttgcaagatt tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg
     1261 ctcacctttt tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca
     1321 tcaattgcat tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc
     1381 cacggcgcat cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg
     1441 tcgcaaatga cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag
     1501 tcccgcaaca ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata
     1561 tctgaatcta aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt
     1621 aatccgttga tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca
     1681 tctaaataag tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt
     1741 gtttgcaatc caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca
     1801 actacttcat ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt
     1861 aaattgacta cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta
     1921 aaattttgga aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg
     1981 atttctttct ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa
     2041 ccagatacac tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag
     2101 tcaaatcctc catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg
     2161 taattccaag aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct
     2221 tctttctgta agagttatct atttgttttc ttttttctct atacactgga taagtcaggc
     2281 acagccaaga aagactgagt aagtagccgc cgatgatatc agtaggaaaa tgaacgccca
     2341 gataaatgcg gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg
     2401 tgcgtaaggt tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa
     2461 tcatactgcc tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg
     2521 ccaatgaagg acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa
     2581 ttacaataaa tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc
     2641 ataaagccgc acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa
     2701 agagttggta gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat
     2761 cgaaaccaga aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga
     2821 caagaaagaa gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt
     2881 gaagcaatga cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac
     2941 caatgtatga ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga
     3001 aagacatttt ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa
     3061 tccttttaaa caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt
     3121 acggtaaatt acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat
     3181 attaagagaa gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga
     3241 aaacattgca agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa
     3301 acgaggggca gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt
     3361 acagccggtt cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac
     3421 agcggcattt atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct
     3481 atatgcatca gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt
     3541 atctcaagca ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt
     3601 ctacatggat acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg
     3661 acaatatcct tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc
     3721 atttggcaac ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga
     3781 tgcgacagct tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa
     3841 taatatcatc gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg
     3901 cggtggagcg actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag
     3961 caattctggt aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg
     4021 tgattctgtt tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg
     4081 gaacaacatc caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca
     4141 ggaaaatggc tcttcgacga ataattccgg taacaatacc aactcttcag gaaatgctgg
     4201 tacatcaaac ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt
     4261 ttggaagatc tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat
     4321 caagaacaat ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa
     4381 tgctggagca aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc
     4441 aagttcttct aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg
     4501 gagcgtctca aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca
     4561 aaataacttt atctacccag gacaacaact gactgtttca aacagtggat caacaaacag
     4621 cacgtcaggt aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg
     4681 cagcagttcg tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc
     4741 aaataaaaac ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt
     4801 catttatcca ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg
     4861 ttcaactact tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc
     4921 atccactggt aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa
     4981 caaacatcat atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat
     5041 ctatccagga cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc
     5101 agttactggt tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga
     5161 cagtcatgga attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat
     5221 ttatccaggt caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt
     5281 gaattccaca aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg
     5341 aagtagtaaa aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc
     5401 ttttgaactc gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg
     5461 gccgttacaa cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta
     5521 cgtcctataa aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag
     5581 aaaacaaagc aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat
     5641 aatagaaaca agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga
     5701 aattgagaaa aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga
     5761 tcctgaaaag ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct
     5821 acatgtaggg catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag
     5881 tcaaggatac aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca
     5941 atatgcgcta gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt
     6001 ccgacgccaa atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac
     6061 tgatccggag tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct
     6121 agcttatgaa gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa
     6181 tgaagaagtg atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat
     6241 gcgccaatgg atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt
     6301 agttgattgg ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg
     6361 agcaaatatt gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg
     6421 accagatact ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag
     6481 agaaattacg acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa
     6541 aaaatcagat ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc
     6601 ttatgcaatc aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt
     6661 atcttcatac ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga
     6721 attcgctcaa actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa
     6781 agctgcttac acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa
     6841 acaagaagca atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga
     6901 agtcagctat cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat
     6961 cccaatcatc cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt
     7021 acggttgcct aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa
     7081 tatcgaggag tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac
     7141 gaatacaatg ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca
     7201 taacaaaaaa gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta
     7261 cattggtgga gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt
     7321 cttatacgat atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg
     7381 aatgatctta ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc
     7441 tgatgatgtg gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg
     7501 gccattagat gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt
     7561 ggatcgtgta tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac
     7621 attgaatgat ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga
     7681 ctatgaaaat cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc
     7741 ctataaagtg gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc
     7801 gattgctcct cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc
     7861 ttacgcacca tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt
     7921 tttccaagta aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga
     7981 tgagctagaa aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac
     8041 agtcagaaaa gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc
     8101 tctttgtcaa taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca
     8161 ttctgtctca gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga
     8221 ttttcatgtt ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct
     8281 ctgtaatcat caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga
     8341 aattgagagt acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga
     8401 ttttgacgca taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt
     8461 attatcgaag tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa
     8521 agaataatgt tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct
     8581 gtatcgttcc tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa
     8641 ttaaataatt tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt
     8701 gtttttcttc tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg
     8761 cttagtcaaa gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat
     8821 ctttattttg agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag
     8881 ttattgctga gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc
     8941 ggaatgaaca cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag
     9001 tcttcgcctg gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc
     9061 attcttttag ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat
     9121 ataaatgctg cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca
     9181 aatgaagggt tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat
     9241 gatctcaaac ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat
     9301 tgggtatttg tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg
     9361 gggctgattc ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca
     9421 tggtttatct attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa
     9481 acatggcaaa cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta
     9541 ttttatggca acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact
     9601 ttgtacattt acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg
     9661 atcaatcagc cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca
     9721 cgtgaaagtt tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg
     9781 attccggaaa actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact
     9841 caaataagcg cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat
     9901 gcagggaaaa tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc
     9961 gttcagcaac tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg
    10021 ttcagcaccg agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt
    10081 gtaactcgtg attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc
    10141 gtattttaca agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt
    10201 aaaaagggat tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc
    10261 caaaaagtat cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa
    10321 aagctatcga tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac
    10381 gctatctgaa attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca
    10441 gaatgtgttc ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt
    10501 tcaatcgttg acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc
    10561 attgcttgct gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa
    10621 ataacgacag gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct
    10681 tgagataacg tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga
    10741 ataaagtgat cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc
    10801 attttcccgt aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa
    10861 accatcccaa aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg
    10921 aattcgatct ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt
    10981 tttcctgcac cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg
    11041 acttgattca tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt
    11101 tttcctttcg gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca
    11161 tctaatatct caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca
    11221 taagaagcgg tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag
    11281 aagccgatcg tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg
    11341 aaggcgagtt gattaatgaa acgaatggcc ggatagatag cacagttcat aaattgagca
    11401 cgtttaaaag cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct
    11461 tgctgattga atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt
    11521 aaaacaccca gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta
    11581 gttgtaacaa ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg
    11641 atataaaaca gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg
    11701 atacctgtca ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg
    11761 tcacctactt gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt
    11821 tcttttcgca ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata
    11881 aatgaagtga tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat
    11941 gcttgtttga tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag
    12001 agatcatcga tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat
    12061 aaactgcata gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa
    12121 cgtatcaaag cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata
    12181 ttccttgtga ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag
    12241 taccttgtcc aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg
    12301 tactgaggcg ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg
    12361 ctcttaatgc tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga
    12421 tctctgctgg tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat
    12481 aattagaacc gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt
    12541 cttctaattg agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc
    12601 ccatctgcaa gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac
    12661 tgatgtggga gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta
    12721 cttttcctat cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag
    12781 atccggtccc gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt
    12841 ctagaactgg atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat
    12901 ttgtctgatc aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct
    12961 ctgcttgcag tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca
    13021 ataccatagc tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag
    13081 tcacgacacc gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag
    13141 aagcataaac gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt
    13201 tcactttgat catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat
    13261 atgattgatt atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga
    13321 tggtgatccg atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca
    13381 gtcgataaac aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata
    13441 gagaataacg aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca
    13501 tttggcaaaa taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca
    13561 aaagagatcc agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga
    13621 aatatttctc ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag
    13681 aggcaactgc agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt
    13741 ttataactga ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg
    13801 gtacacctaa tgtaccggcg atttctaaac agatcatcac aaaggtaagg agagcgagtc
    13861 ctttgttttt ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat
    13921 acttttcgat tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa
    13981 aaagaggtga gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga
    14041 tttgccaaaa tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca
    14101 agaagagaat gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt
    14161 tttttataga aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt
    14221 gacggagtta tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt
    14281 gatgaaacaa aaacaaaaag agataaggga gcaaaaaaaa cagttgaaat tgatgatcga
    14341 tacaaacgag gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga
    14401 gtttgaagat attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat
    14461 gagtatgcca gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt
    14521 acatttattt actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt
    14581 cttattgaaa tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag
    14641 aatgtatgaa aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac
    14701 ggatgaaaac aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga
    14761 aatatgtgtt taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct
    14821 ggttcgatta cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt
    14881 tttagaggaa atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg
    14941 taattgtcct cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat
    15001 ggtgaactga gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat
    15061 gagaatgata aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac
    15121 attattacaa tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt
    15181 aatcaaatag tccctactgt gactttcctc agctatcggt gatactaccg atagcatttt
    15241 tttgcttata aaataattat aagtatttag agatttttct tctaacattc ttcaaacaag
    15301 aaaaatcaca aaggttattg ttatttttat atattctttt taagaatgat tgttttttta
    15361 tagaaatttt aaaaaataaa acacgttatt gatggatagt tagtttgtta tttggtaata
    15421 ttatagaagt tgactggtag tgatttattt ttcgtcgttt tataaaaatg ttattttttg
    15481 gaaaaattca caaatatgta acgaatgttt ttctggaatt tgctgtgtta aaaagcagta
    15541 tgactaatat aaatactatt gtcatttatg caatttttta tggatagtaa ttttagaggg
    15601 gaatcaatga aggaagaata gaagggaaaa atagttgcaa atacgccagt tagcaaaaat
    15661 agcaatacat cttcaagctt taaaattcga gagaatcatc ttggtagtgg aatcaactac
    15721 aacaaaagga ttaaaccaat taatagatag aattaccaat ggaaaaatag aaaaggtagt
    15781 tattctatac aaaagttgtt taattcgctt cggttatgaa cttagtgaaa ccctttgcaa
    15841 tatatggtac agaatataga aattattgac attacagaaa atgatgaaga tttaatacag
    15901 attgtcacta tttgtagata ccttttacaa ggaaaccgag ccaataaagc taagaagatg
    15961 attaaggagt tgatggaaga cgatacaagt taagaaagtg aaactacgcc caaataaaga
    16021 gcaaaaagag taattggacg tggaaaatgc aagaaatgaa ccatcgattc ggtggacagt
    16081 ttattagtaa tgacggtttg agaacatcca tgacgagaat gaaggaacat cctaaatgcg
    16141 tttagttgaa ccaagtgcca aataatatgg ccaaataagc gatcagttat cgatgaatcc
    16201 caagtattct aaactatata ttcattttga tgctaagcat tgatatattt ttttgggatt
    16261 gatgaaggtt aaccaataca gggactcact gatgaaattc tagagtctga ccttggtatc
    16321 aacgatttag tgattgtttc taatggaaaa gtataaaagt atataagtac attaacaaaa
    16381 taactattag ggttacgctc cagcttgtgc aaggcactgg caggaggaat cgtgaaatca
    16441 taattatggt taagccacac ggacaactaa aagtcataca aagctatcga atcaatcaac
    16501 agaagacaat cggcaatcat tagctttgtt tacagcttac attgcaacgc ttgagttgaa
    16561 ccgaaaatac gagggaggta acgcagccat tttgagttgg ggaatctttt tagaaaatta
    16621 tcgggtacct tgttgtttag tcaaaattat aagggggagt aatagtgagg aacaaatttc
    16681 ataaactgtt aagtatgttt ctagttatgc ttattgtgat caatcaattt gggaacataa
    16741 cggttctagc tgagtcttta gcagaacagc cagagcgttc gctgacgatc gaagttgatc
    16801 aagaggaggc tgctttgggt gagcagttcc agttgcgagt cagaggaaca ccagacctgc
    16861 taaatgcatt ggtcattgat aagagtgagg atttgattga aggggaagtg aagcaactca
    16921 atgattacga acgtctgatt acttattctt cccagcattc aggtaaatac gaattgaccg
    16981 caagaagcgg tgatattcaa tcaaatacgg tctcaataga aatcagtgta ccagaagaaa
    17041 gcacaagtga gtcttttaat gtaccagaag aaagcacaag tgaatctttt aatataccag
    17101 aagaaagctt aagtgaatct tttaatgaag ccagatcatc tgagccatct ataacgcagg
    17161 aatctcagat tgaaagacaa gaggagctct tgaattatga catcggcatc tctgctgagc
    17221 gccccacttt gccgagcagg catacacaaa cgttaaaggg atacattcaa ggaggcgctg
    17281 gcgatattct tgaagaatat ggggagatgg tcgtacgagt tcctagagca tcgattggct
    17341 taattgagtt cattagagtg gaggtcgctg atgattcacc tttaaagcca ctggcatttt
    17401 accaagaagg cacagacgtt gtttttccat ttacctttga ttatgaagga ttaaatgaag
    17461 ccgctcagtc gtatacattc agtatcacgt ttgaagttgc tttctttcaa tcaggcggta
    17521 ctgagccaaa taatgacttt caagtgagtc ttacttatgc tgagcgagca gcaaacacgg
    17581 aattttcaat tacgcctatt ccttcatcaa gacccatttt ttcgaaatta tactatggct
    17641 ctagagaaat cgacagccaa ggaaatcttg ggaatctgct gattgacggg caagacgtga
    17701 ccaacagtaa taaatttatt ttgcaggtaa attatgaagg atcacgaaaa gacggtgtag
    17761 tggttaccga tgtactaccg caaggaacaa ctttggcacc gaatccgact acatggagtt
    17821 ccactggaaa tagagaacct atttcaggtg gggttcggat cgcagaagta acgaatccag
    17881 gtgaagcaaa cgttagaact cattatgttt ccgaggaatt tgtggacaaa gtatctttta
    17941 ataaggaaac gaatacactt gttgtggact ttggtaatct agcagagggt caatcgtatt
    18001 ttattgaata tgctcttgaa gtgaccgatg tcgacttgtt caatgaagga agacaagagg
    18061 atgggttttc tcggaatcga gcgagtatga cctacaataa tcaggtaatg agccgagact
    18121 accgcttgag aatccctgaa agtaatcttc cggcaatctc tttaagaaaa agtgtggaca
    18181 aaaatgttat caatctcaat gaaaatgaac taacgtatac tctgcatgtc tcgatgtttt
    18241 ctggaacaag aaatacgctt gttattgaag atgttttgga agaaggcatg gaatttgtgt
    18301 catttctatc agatattccc tctttcattg atgccgaagt caataatgga atagttcgtt
    18361 tcagtgcgaa taatacgatt ggtggtccga caagttttac cctctctttt aaggtcaatg
    18421 tagaggcgta tgcggtcggc gatcaaattt taaactttgc aacgcttgtg aatagtgaca
    18481 atcgattgaa tacgagtact gtaagaacaa ggaaaatcga tgggcgtatt aaagtaatta
    18541 aaactgatga gaatggccaa aggctggcag gagcaaaatt tgaaatttta tcaagcgatt
    18601 cacaagtgat acaagaaggt ataacggcag aaaacggaga atttttaagt gaaccgcttc
    18661 ctgtaggtag ctatcaagtc cgagaaacag aagcaccgga agggtatctt ttagatgcga
    18721 cggtacatga tgtttttata aatgaatact ccatagaaga agtgacgtta accattgaaa
    18781 acatccttga tacgggtggt gttgaactaa ttaaacatgc tgaaggcagt ggtgaagtcc
    18841 ttcaaggagc tgtttttgag ttacagaacc gagaaggaga aacgctacaa accggt
//
LOCUS       DAKCAA010000051        18011 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000051 DAKCAA010000000
VERSION     DAKCAA010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.051"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            282..521
                     /locus_tag="OUE31_001967"
     CDS             282..521
                     /locus_tag="OUE31_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222957.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="OUE31_001968"
     CDS             complement(883..1143)
                     /locus_tag="OUE31_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222958.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1328..1825)
                     /locus_tag="OUE31_001969"
     CDS             complement(1328..1825)
                     /locus_tag="OUE31_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HCU0222959.1"
                     /translation="MWTEKQKKDTYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1955..2665)
                     /gene="budA"
                     /locus_tag="OUE31_001970"
     CDS             complement(1955..2665)
                     /gene="budA"
                     /locus_tag="OUE31_001970"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HCU0222960.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="OUE31_001971"
     CDS             complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="OUE31_001971"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HCU0222961.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4547..5209)
                     /locus_tag="OUE31_001972"
     CDS             complement(4547..5209)
                     /locus_tag="OUE31_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCU0222962.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5219..6034)
                     /locus_tag="OUE31_001973"
     CDS             complement(5219..6034)
                     /locus_tag="OUE31_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCU0222963.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLYESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6288..6731)
                     /locus_tag="OUE31_001974"
     CDS             complement(6288..6731)
                     /locus_tag="OUE31_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HCU0222964.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6865..7203)
                     /locus_tag="OUE31_001975"
     CDS             complement(6865..7203)
                     /locus_tag="OUE31_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCU0222965.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7191..7568)
                     /locus_tag="OUE31_001976"
     CDS             complement(7191..7568)
                     /locus_tag="OUE31_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCU0222966.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7792..8985
                     /locus_tag="OUE31_001977"
     CDS             7792..8985
                     /locus_tag="OUE31_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0222967.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9151..9531)
                     /locus_tag="OUE31_001978"
     CDS             complement(9151..9531)
                     /locus_tag="OUE31_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0222968.1"
                     /translation="MIHLLLETERWCSIEELQNELKVSSKSILNYLTDLEELFQKYPD
                     KVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQHPEKNLEDYADAQY
                     TSVSTVFRYAKLLVKYFEMTDVKE"
     gene            9784..9978
                     /locus_tag="OUE31_001979"
     CDS             9784..9978
                     /locus_tag="OUE31_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222969.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            9975..10469
                     /locus_tag="OUE31_001980"
     CDS             9975..10469
                     /locus_tag="OUE31_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222970.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(10631..11803)
                     /locus_tag="OUE31_001981"
     CDS             complement(10631..11803)
                     /locus_tag="OUE31_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCU0222971.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12009..12824)
                     /locus_tag="OUE31_001982"
     CDS             complement(12009..12824)
                     /locus_tag="OUE31_001982"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCU0222972.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(12974..13420)
                     /locus_tag="OUE31_001983"
     CDS             complement(12974..13420)
                     /locus_tag="OUE31_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HCU0222973.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(13417..14421)
                     /locus_tag="OUE31_001984"
     CDS             complement(13417..14421)
                     /locus_tag="OUE31_001984"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCU0222974.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(14461..14790)
                     /locus_tag="OUE31_001985"
     CDS             complement(14461..14790)
                     /locus_tag="OUE31_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HCU0222975.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(14916..17243)
                     /locus_tag="OUE31_001986"
     CDS             complement(14916..17243)
                     /locus_tag="OUE31_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCU0222976.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         5218 a         3539 c         3137 g         6117 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atgatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccgg ctctttttat tcttgatttc tcttcttttt tgtttcaata
     1321 gacgatttta gttattaata aatgaaaaag catttatatt aaaatttgct aataaaagat
     1381 ctacatattt ttctagaaat gcttgatcga tttcatcata ccctttcgtt actccgcaat
     1441 cgatatctaa aacaccgatt aaattacctt cttttaccat tggcactacg atttctgatt
     1501 gtgcggctga atcgcaggaa atgtaatttg catgggtttt gacatcatca acgatcaatg
     1561 tttcttgttt ttcagctgat tctccacaaa ctccttttcc catcttgata cgtgtgcaag
     1621 aaactcgccc ttggaacggt cctaaaatca attcattacc atcgaataaa taatatcctg
     1681 caaagacagt ctcaggcaaa gtctcattca acaatgcaga tgaatttgct aaatttgcta
     1741 accagttatc ttctgcttct aataatcctt gttgctgtaa taataaaatt tcgtatgtat
     1801 cttttttctg tttttctgtc cacatgataa aaaccgctcc tttttgatct atggagaaga
     1861 ttatagctca gtttttttgt aaacgctagg tttcctcctc aaaaaaacga gatacgtcag
     1921 gttaatcacc ttgaacgcat ctcgctgtct ttttctattc tgcttgttgg atttctgctg
     1981 ctaaatcagc ataatcaatc gtttcgtgaa caaaagtcgg atcatcaact ggaaaatgct
     2041 gtacaaggga cgagatgcgg ctaatctcaa cttttccttc agccacttca aaatccatta
     2101 catgtccgcc aaatgtatgt gtatcatcga taaaatgcaa gtgaaatcct gctgcagcaa
     2161 ctccttggaa taattcaggc gtaaagaacc cgactaatgt tccttggaca ttgctttgtt
     2221 ggaattctgg ttgagactct gaaatttttg ctagtcttct gtaaggtttt tcttgcttcg
     2281 gcatgatacg gatgtgcata tttttgaata atccagttat cttcactgcc aaaaataggt
     2341 tttccccggc ttctcttact aatatgtctt ttttcaattg ttctccatct gcagtttttg
     2401 agacagaaaa actagtatct ggcgtaaaat ctgtaattgc tgcatagggg gtaagttcac
     2461 ttccatctaa ttgggcaact gagccatctg atcttccttg ataagctacg ccatctaaaa
     2521 agatgacttc accatcaagc ccatgcaatg ttcccaatcc cagagttcct ttttctaata
     2581 tatgagcaat cgtttctgtt ccatccatca agccagccat caaagctcct aatgtcccgt
     2641 gctggtataa gattttttca gtcatgtcga cacttcctta atagaattga tctggtaaga
     2701 ttgtttctcc caatttctca ttatcacggt aatcaatcgg aatatcaata attacgggtc
     2761 cttctgtcgc aaatccttct tctaaagctt tttctaattc ctctacactt gtagctcgga
     2821 ttcctttagc gccaaaagct tctgcatatt tcacaaaatc aactggacca aagtctacac
     2881 ctgacgcccg ctgatatttc attttttctt ggaactctac catattgtag tgtccatcat
     2941 tccaaatcaa atgaacgata ttcaattttt tacgtaccgc cgtttctaaa tcctgggcag
     3001 agaataaaaa tcccccatcg ccggaaactg atacgatttg tgtatttgga cgcaccaatg
     3061 cagcagaaat cgcccatggc aatgcaacac caagcgtttg cataccatta ctgaataaca
     3121 aatgacgagg ttcataactt ctaaagtggc gtgccatcca aatataatga ctacctacat
     3181 ctacggtaac agtcatatca tctgttactt ttgactgaag cgtgttaata acttctaaag
     3241 gatgcaagat acctgcttct ccttttgatt gaacaatgtc ccgctccgtt aattctgctt
     3301 gaagagatgc taaatattct tttgcatctt ctgacacttg ttgaggctct aatgaacctg
     3361 tcaataaatc aagagtggct gagatatcac cgatcaattc tctttcaggc tgcataaaag
     3421 gatcgatttc agctggcgct tcatcgatca caatgatccg cgcatctttt tccgcattcc
     3481 agtttcttgc ttcatattcg attggatcat agccaatagc aataactaga tcacttcgtt
     3541 tcaaaagcat atctcctggt tggtttctaa ataaacccac acgaccaaag aaatgcgctt
     3601 ctaattcacg tgagatcact ccagctgctt ggaatgtctc tacaacaggc aatgctgtct
     3661 ttccaactaa ttgcctgatg gctaacgttt ctttttcact tgatcctcgc atacctacta
     3721 atagtaccgg tagttttgct tctctaatgc gttcagctag gtaacggata tcatctgcag
     3781 aagcagaacc taatttagga tcgctcaatg gcttgatgac attcccttgg acaggtgcat
     3841 ccactacatc ttgcgggata ctgataaagc tcgcgccttt ttttgaactc ttagccatac
     3901 gataagcatt ggcaatcact tctgaaattg tttctggatc ttggatttct gcactgtatt
     3961 ttgtgattgg ctggaacagt gctgcattat ccatgctttg atgggtcaac ttcaatagat
     4021 cgcttcgttt tacttgtccg gcaattgcta aaactgggtc accttctgct gtcgctgtta
     4081 ccaaacctgt agctaagtta ctagcaccag gaccacttgt tgcgataact actcctggct
     4141 ctcctgtaat acgtccgatt gcttgtgcca taaatgcagc attttgttcg tgacgagtca
     4201 cgattaattc aggaccttga tcctctaatt cattaaatac accatcgatt tttgcacctg
     4261 gtataccgaa tacataatca acatgatgat taatcaaact ttctactaca gatttcgaac
     4321 cttgtttcat tttttcgtcc attgaacatc gtccttttta tgctttattt ttaattatta
     4381 gttagaaata atcacaaata attgatacag tttctaaacc tgtttcattc aaaagtatag
     4441 cacgttttat ttcatttgtt tagccatatg tttcaaaaaa tgaaaaagaa tgacagtttt
     4501 tacataaaaa ctgtcattct taattgaaag tttcaattta taaagtctac agatccatag
     4561 ttctcatcaa tttacgattg ttgaagtaaa tcaaaccaaa tacgatagaa ggacctagta
     4621 gaatacacca ttggggcttt acgaaaaaga agagaaacaa acttgtcaat agtaaaaaat
     4681 ctagtaaact cacataccat tttttcaacg tatagtagaa cgctatccgt agaacttgat
     4741 ttggtttcga cgctggattt ctcacctgaa aataccagta gttgatgcta aaggaaactg
     4801 ataaacaagc aagtaaaaca aacaacggaa tcaaccattt tccataagaa aaacgtataa
     4861 aaaagaaaca atcaaaaatc attatcacac taactatcca agcaaatagc caataaaaaa
     4921 atccctttag ccaaaattgg cgaaacgtct ttatgaacaa acgtactggt gaaaaacttt
     4981 tttcttttgc taattcttct gtcataccta tcatcacgat gcaacctgga ccaataaaaa
     5041 gtaaagaaaa aataaaggaa aagacattcc ttccatctat cgacaaaagg aacgcagctg
     5101 ctatatacaa gatattgaca caccaaaaac aaaggctact tgccaatgat tgatacaacc
     5161 aataaaagaa ttccatataa acatttttgt caaaacgctg ctctttcata atcacctcct
     5221 attccttcat tcctgatgaa gcgatccctt ctacaaaata tttttgcatc gctaaaaata
     5281 taaaagcaac aggaagaaca gaaacaactg aggcagccat gattaatgcg tactctgcat
     5341 caaatagccc aataaacatt ttcaacccta actggattgt tttattttcc gtagaagaca
     5401 aataaatgaa tggccccata taatcgttcc atgtattaac gaatgtgatg atcgtcaaac
     5461 tggcaatcgc cggttttgta agaggtaaaa tgatcttgcg atagattccc cactctgata
     5521 agccatcgat ccgcgcactc tcatataaag aatctgggat actactgtag tattgcttca
     5581 acaagaacac accaaaagca ttgaacgctt gtaatagcac caacgaccac aacgtatatg
     5641 ttaaacccac ttttctcatc ataatgaact gcgggatcat ataagactgc caagggacag
     5701 caatcgtgcc gatatatgct aaaaataaaa tatcgcgccc tttaaaattt agtttagaaa
     5761 acccgtaagc agcaaaacta gaagtaaaca actgaatcaa cgtgatcaca acgcttaaaa
     5821 aagctgtatt cttaaaaaat gtcactaaag gaatacgaga ccaaataacc agataattct
     5881 ctaaatgcca agttttaggg atccattgaa tcggaatcgt gaacacttca ttatttgctt
     5941 tgaatgaagc agaaaccatc cataaaaaag gaatgatcgt caataaagct aatacaatca
     6001 gcagaatcat acccaaccat tgaataaagg gcatgttttt tgaacgaatt tttgcttttt
     6061 ttctttcatt tcgaacacct ccaaagttat aatcttcatt tctttgtaat gattacaatc
     6121 cagaacaacg tagctgattc atttccgttc ttcttatgtt tgtaagcgct tatttaacaa
     6181 gttatgtaaa tctctttatt tttttgattt aaaaatgaaa aaatacaaaa gcaagactgt
     6241 catacgtctc gcttttgtat tgaaatttct tcgattagag atacttatta ctgttcaaaa
     6301 gcttctttga aacggtgaat caattcattg actacaggtg ataaaatccg attctttttc
     6361 cagactagca tgcagttcgt ttcaatcatt gggtcaagcg gaacgaatgt cactcgcttt
     6421 gaaagatgac ttacagcacc ttctatgact aaagcagcac ctacctgatt ctcaattagc
     6481 gcaaatacat tgaaaatcaa attgtacgtt cctgtgatca gcaactgctc cttttttatg
     6541 cctaaccagt cagcaaacat tcgctgtatt tctggacgct ttgagatcaa aagaggtaca
     6601 ttcgcaaagt cttcttttgt tatcacgtct ttttttgcta aaacagaatt ttctaaaatg
     6661 agcaatcccc atttttcctt tcttggtaac aaaatcgttt cgtatttctc tgtatctact
     6721 ggatctagca aaatcgctaa atctaacagg cttttttcta gtcactccgt gatatcatca
     6781 cttgttccgc tgtggatatg aaattgaacg ctgggataat cacggatcaa cttttctagt
     6841 aatagtgcca atgtattcga attatcagct tccacacagc cgatcgtaaa tcggccgctg
     6901 aataattgtt tttttctgtt ctcgaattct tgagtggttt gattcgttaa atctaaaatt
     6961 tcttctgctc ggctttttta gaaaataacc tgcttctgtc aagatcattt tgcggttttc
     7021 gcgtacaaac agttctgttc ctagttcctc ttctaactcc ttcagttgtc ggcttaaggt
     7081 tggttgtgta agatgtagaa cttctgcggc ttgagagatt gttccttctt ctgcaattgt
     7141 ccaaaaatat tttagtaagc gtaactccat agcgatgctc cttgattttt ttacttgata
     7201 cattccattt tatttctaga taacacacga tcatatttct tgatttttcc ttgtaaacgt
     7261 tccaaacact cttgcatttc agcaatttct ttcgtcaaaa gttcactttc ttcaatcaaa
     7321 agcttacgcc gctcaaatac agttgcttct ccttcgctag ataggcgaat atattcaatc
     7381 aaagactcga tcgataatcc ggcatttcgc atacagatcg taaagtcgac ccattttagg
     7441 tcttcttctg tataatcacg gattccgcct tttgtccgat taactggtgg aatcaacccg
     7501 attcgttcat aatagcgcaa tgtatcggcc gaaatgccct tttcttcact gacttgtttg
     7561 atattcatct gatcactctt tctcttaatt tcttgccact ttacttatgt attttattta
     7621 ttctacaact ttaagtgtac tccaagtcaa tactcatttc tattaaaact aagctggatt
     7681 atctatatcg gttgtttgtg tattatttca aataaaaaag tcttgttttt ttattctttt
     7741 ttggatatac ttttaacaat ttagggaaat tttaggaaaa ggggtataaa aatgacaacg
     7801 tatcagcgaa aggtattatt atcgacatcg gcgggaattg ctttagagaa tatggatatt
     7861 atgtttttag ctttttcatt atcttcaatg attacttctt ttcatattag tggtacgcaa
     7921 gcgggtttca tttcaacgat cactaatttg gggatgctca ttggaggtat tttttttggc
     7981 atcatagctg ataaatatgg acgtgtgaaa gtattttctc aaacggtcct tctgttttcg
     8041 attgcttctt tattgatgta ttttgcttca aacatctact tggtttatct ctttcgcttt
     8101 atcgcaggtg taggagcggg aggagaatac ggggcgtgta tgtccttgat ttccgaaagt
     8161 ttttcaaaaa aacaaattgg acgagcttct tcggttgctg gtattggtgc gcaggtcggt
     8221 gcggctttgg ctgcgatttt agctgctgtg atcattccaa cgtttggttg gaagatgttg
     8281 tatgtcgtag gtgtactgcc ggtgttgatg gtcttgttca ttcgtcgcgg cttgactgaa
     8341 ccaaaggaat tcaaatctgt acaatctgcc gaaaagaaaa ccaaacttag cagactgttt
     8401 gaatcaaaac atcttgcttg gcaaacatgt ggccttagta tcatggtaac tgtccaaatt
     8461 gccggctatt ttgggttaat gaattggctg ccttcaatta tgcaaaatcg attagggctt
     8521 tcggtttctg ggtcttcatt gtggatggtc agtactattt taggcatgtc tttggggatg
     8581 atgacttttg gcataatcat ggataaattg gggcctaaac tagccttttc tttgttttta
     8641 atttgttcat ccttatctgt ctatctactt gtgttagccc atagccagtg gagtttggta
     8701 gcagccgctg tgatagtcgg ctactttatc aatggcatgt atggtggata tggcgcagtg
     8761 attagtagtt tgtatccaac agaaatccgc gcgacggcga ataatttcat tatgaacctt
     8821 ggacgagctg ttggtggttt ttcttctatc gtcatcggtt tcttgatgga tcattatagt
     8881 ttaactgccg taatcttgtt tttgagcggt atttacctag tcagtctgct ggtcttgaca
     8941 actcttactg gtgttacagc attaagggaa agcttgcagc attgatagtt gagtctgtaa
     9001 atgacaagaa agaggtgtgg caaaagcttg catctgcggt aataagacca gccaaatcaa
     9061 aaacatgaga cactgtttcc gtttggctgg tcgtattact tgatgcaggg cagctttttc
     9121 aactgctaat ttccttctat ctggcggcga ctattctttg acgtccgtca tttcaaagta
     9181 ctttactaat aacttagcat aacgaaaaac tgtggataca ctcgtatatt gagcgtctgc
     9241 ataatcttcc aaatttttct caggatgttg atacatgaat tcaatcaaat gataattata
     9301 tgattttctg tagaaatgaa gataaataat gtagattggg aagttctcct gcttttccat
     9361 agaaaagcgc cgattattct cattcttcaa aatgacctta tcaggatatt tttggaacaa
     9421 ttcttctaaa tctgttagat aattcaagat agacttactt gataccttca attcgttttg
     9481 tagttcttct attgaacacc aacgttctgt ttcaagcagt aaatgaatca tttaatcgtt
     9541 tattatataa atgtcaataa tctaataata aaataacgta catattttat tattgcatac
     9601 ttaataacag aactatagca aaaaatcccg tgtatcaaca cgggattaga ttaagtttcc
     9661 tcaatcacta ttcataacac aattattata acaagtaagt aaacaattga aaaggacatt
     9721 tattgaaaac ggttgttttt tacttaagga ggaaatttag cgaaaaaatt agttgcattg
     9781 tttttggtcg caggaagttt gttgagtggg tgtggtgcta ctacgtctac tactcaaagc
     9841 acaagttcag atcaggcttc cagcagcagt accacgatct ccgaaagtac ggcagattca
     9901 tcgaaagaac aagaacaaat tgaaaagaaa aaagaagaga aacaaaaagc ggaaaaagct
     9961 gcactagaaa aaaagtgaca gaagcggaat ctgctttgtc acaagctgaa gcaaatccta
    10021 caaaagaaaa ctatgcaact gcttcagcag ctatccaagc gctacctgaa aacaaacaag
    10081 agttgacaag ccgtcttgct gcaattgatt ccacaatcaa agcaaaagaa gcagaagaag
    10141 aacggaaaaa gcaagaagaa attgcacgac aacaagcaga acaagcgcaa caagaagcaa
    10201 tcgcacagca acaagcagaa caggcgaggc aagaagcaat cgcacagcaa caagcagaac
    10261 aggcgcgaca gcaatcagca gctgaacagg cctctcagca ggcacaagcc gcagctcctg
    10321 agcaaaataa tgaacaaact gtctatgtca caccgaccgg ttcaaaatac catacacata
    10381 aatgtggaaa tggtacgtat acccctgcca ctttaagcga agctcaagct cgtggtttaa
    10441 ccccttgctc caaatgttat ggaaactaat tcaaaagtta tactataata ataaaattct
    10501 tctgaaacat aaaaaaatag aagatggcgt tccagatagt aaaccaaaaa taacagttta
    10561 cacgtccatt tcgtcagctt ctctcttttt tcatttagtc tgttccctct gcttttttgg
    10621 acatcttcat tcattctttc tcaatcaaat agtacacctc tttttctttt cgcagtttat
    10681 atcttccttt tttcaatttc attgaaaact gtttcgaatg tttatgtttt acatggattt
    10741 taagcaggag ctcctcatgt tgcaagcgat agttcctgcc ttttaaatca gaaaatctca
    10801 ctagtccgta ttcatcagaa gctttcacaa atggaacttt ttctctagta atatagtgtt
    10861 tgccgttgag cgtttttaca gaaaagacca ttccttcgat tggtcgtccg tttgtgttct
    10921 ttacataaaa agataaagga tagtttcgct tagcgatggc caaagaatct aaataagcga
    10981 tgagtagcca aactaagccg attgatccaa gtagtatacc gataaaccaa ataaaaaatt
    11041 tccatttttt ccattgatca attccttgga tcgctttttt tgcctctttt gcttgataag
    11101 gaatacgatg ccccgtcaca agcagtcgat gtgtattgac catataagga gtacaggtaa
    11161 gcaaagtcac gagatctctg cctttttgga tacccaaaga atctacttca tcaggtaaga
    11221 ccacttggat tttttctact tgatacgcca atgtctttcc attgatctgg atgaaaaact
    11281 ggtctccttt tttcaactta ggcaaatctg taaataattt tgcttctggg agtccacgat
    11341 gcccagaaag aacggcatgg gtgtttttcc cgccagtcgg ataagaactt tcttccaata
    11401 atgacgttcc tttttgcaaa aatatttccg ttgtctgatc gaatataggt aagctgacat
    11461 tgatttttgg gatttcgatg actccaagca tatgttccat aaaaaaggca ttactaggta
    11521 aatcttttaa tgcttttgca tcaactgctt ggttgaaact gcctatccct ggtgatacgt
    11581 tttgctctgc caactgttgg tttttctttg tcattttttc ctgctgtttt tttatttcct
    11641 ctgaattctt attcgatgct tgcttttgat aatggatgat catttgctgg gcaagaaaat
    11701 cattcagtga atcttctaca aaaggataag aaaagatccc gatcccaacg actaaaatga
    11761 ttgccatgaa gatgtccagt attcttattc tgcttttatt catcatgtcc acctattttc
    11821 taatatgtat atgaagaggt tgtgaaatca gcgccttgac ctgagtatta gcgaagcaaa
    11881 cggcaaaata gttcctccta ttttgccgtt tgttgagcga ataccaagag accgaccact
    11941 tgtcacaacc tttctcccca tttgaatcac tatcgtttat ttatcgtatg atttttgttt
    12001 ccaatagttt aagcttctgt ttcttgatgg cgttttttga aatagatcac tgctcctcca
    12061 actaaagcag tacctaccaa gatgaatacg atgatcccca taccaccagt tgaaggcaag
    12121 attcctttag gttggttatc gatcgttgtt tcatcagaag ttgttggatc atcatctact
    12181 gtaaattcag tgtacgcagc ttcattctta ggtaatgcgt agccttctgg tgcttttgtt
    12241 tcttgaaggc agtatgcccc ttgtttcagc ccttcgattg aaaatttccc ttctgaatca
    12301 gaaatcaatt tcacttcttc ccagtcagaa cctgtgactt catctgacca agcatatggg
    12361 tattctcctg aggcaaggtt tgctattttt ttcattaatt taacagttgg atcttttgct
    12421 cttagaatag aaaattctgc atcggctaat ttttcttgcg tgttcacatc ttgtttgatg
    12481 aagtggaaat caccgtagtt ttggacattt tctacagtaa tcgtgttatc cgtagttgta
    12541 ttttcccgat tgactacacc gtttggattc ccaagattgg cttcatctgc gccatggatg
    12601 ataccggttg tttgttgcaa ttttccgttt tttactataa aagtagtttc tttttgtgga
    12661 ttggttaatt gataaccatc tggtgctttt gtttcaacta aagtataatt gccgtctatt
    12721 aatccattga cactgatgga tccttcagta tcagttgtga atgtcaacgc tgactcagca
    12781 ggatcataga gagcgacacc agtgttttca tcaaaaccgg tcacgaattg attctctgaa
    12841 tttttgatct ggaattgcgc ccctgctaac ttatctaccc ctgaaaagtt cccagctttc
    12901 tggattttga tattgctttc tttgatgaca tttttagcat ataggtgaat cgtgtctaaa
    12961 ggtttgtcag ggtctagggt aagcttaaca cgatatttgg cgacgtttcg acaccgggct
    13021 ttggtgtttc tacaaagacg tatacagcat ctttcccatc agatttacct ggaagagtca
    13081 ggttagctaa tccttcacca gaagtcgtta cacttgcgaa gggtgtagcg tctgctggaa
    13141 ctgctgtgtc tttacttgga tagtacgtag cagtgatgtc atatacgttg aattcaacgc
    13201 cgttcaacgg ttcgctattc ggaaatgtca attccgttcc gttgtttatt tgattttctg
    13261 gtgctgaagt gaatttcaat ttatgcaaat taaccgtaac attttctggt gtaggtgata
    13321 cggctgcaga aacctctgca gttcctaggc cgagaacgaa aggaagcagc atgatagcag
    13381 ttcctaaaaa cgtccatatt tttgttttga tgtttttcat tttatttccc tcctattgtt
    13441 tcctttttgt tgttttttat aaaaccaagc tgtccctgtt gaaaggacta gcaataaccc
    13501 taaaattgag aaacctccaa gcatctcttc gcttgttttt ggaaagcttc ctccattttt
    13561 ttcatttgat ggaccatttg tctgcatctg aactggcgtt tttccattat tcgtcggatt
    13621 tgcttttggt tcgttgatga tttccaatgg tataggatga agcggatcat aactgccttt
    13681 ttcaacttca aagagaatgg ttgattgact caatatatat cctttaggcg gtttaatctc
    13741 cactagttcg taacttccaa aagacaatcc atggacagaa aatgttccat ctttactgga
    13801 agtaaaaatc gttgctcttg aatcatcttt ggctacccaa tgatttatcc cgttttcttg
    13861 cgctaagtat tggtcatttt ttttgactag aaattgagca tctgctagtt tttgtttcgt
    13921 ttgccgatcc actttgacaa attgtttgcc tcctgtttgg atggcaagat gtgtttctac
    13981 tgtttgattg tcagtcgtca aacgtacatc gttatcaaat gtcgtttttt cactgttttc
    14041 tttcaatgtc atttggtaac ggatcgttaa tttttttcca gcaaacgaac taagatcttt
    14101 tccagaatct gataagacaa aaccatgttt tattttttgt gtgtgaaatg tatgaatctt
    14161 gtctccacca atcaaaaaat cgatcgtttc tggttctagc cataactgag gatcagctgt
    14221 atctttgatc gtataggttc ctatctcgtt gatgttctca ggaattgtta cggtgatgag
    14281 ataagggact ttatccccat ctgcaaaatc tgtctgctta ttctctactg tttttgttaa
    14341 tgtgagtgca gcaggtattt tttgttcgct ctttggatac aagtggatgg tcgtcaattt
    14401 atgattagat gaatctgtca caggaagcac aacgacaaat ggtgctgatt tttcttttac
    14461 ttaatctgaa gtctttattt ccgtaaatcg gtaaacagcg tcacgacctt gctcatcttt
    14521 gtccgatgca ctaaaagaag caatgccctc ttcctcgtct actgtttttg tcacattttc
    14581 tgccagtatt ttttcactat cacttttttg tgctagtttt ctttgtgcgt cttccacact
    14641 acttccttct gaccgcagct tgtaaaattc atccgagaca tcatatatag cgaaagtaac
    14701 gccgttcaac ccttttactc cttgaaagtt atccgggata tttattccgt cgttttgact
    14761 gatacttggc atcttatcgc tttcgaacat tcgattatgc aaagtaaatg taataggtga
    14821 ttctctagct gacacagtcg gagaacctat aaaaaagacc agtaggataa aaaagagaac
    14881 agcaaatata tccacacgta cattttttgt ttttttcatc gctgttcacc tgcttttttc
    14941 ttacgatgga taaaataaaa gaagccagaa aaaataaaga tcagtcctaa aaagacaaag
    15001 ggcagtagac ctatcccacc tgtcgaagga agcaagagag tcggattgat cgtcaactta
    15061 gcggtatctg ttgcgataat cgtataatta ttgtttacac ttccttcgcc taaactaatc
    15121 gttactattt gtgatccaat atctgtccgg ctgttaactg ttagggtata atccaatgat
    15181 tcgcctaaga caacaccggt aacgtggaga tttccaaccg aaatcgagtg actttgggca
    15241 tcataattaa aggcagcgtc atcgacagta atcactgcgt tagctttata gatggtataa
    15301 gttcctgatg tgttggctat atcagtaaat gacaacttgg gatttgctgc tttgactttg
    15361 tctattccgc tattcgttag tttaattgta tagctgccag cattaaccat attttttgct
    15421 gattgtgcat ctgctgtgta atccatactg ctaagtgcca cttgtactgg agtaagcgaa
    15481 ctagtgacac cctctgctag cttgacatgg attgacggga cacctgcttt tccatcatat
    15541 gtcttactgc cactgagctc taccgcaccg ctgatttgct taatcgtata gacatcagat
    15601 gtctgcacga tagtaaataa atagtttgtt ctggcagcta gtttagctag tccgcttttt
    15661 gtcaattgcc aagacgtata ggttccaatt tcagtaggcg cagttacttc aactcccttt
    15721 tcattcatcg ctttgaaatc agttggattc catgtgattt gatcaatact gagatcattg
    15781 tttaaaaggg atgttgattc tgttttatca ttaaaggcat atttaacgat cggtacaaca
    15841 gaaagaccat catagtactt actgccattt gcattgattg atactgttgc atttgtctta
    15901 taatatagga tgacttcaga aatctgtttt ccatttgcgt cctttacgat tacatttcca
    15961 tttgtatcta aactagctaa aacactcatt gctgattggt tctttgtttc tgtcgctgaa
    16021 acagctgtaa aggtatatcc gttgatagta ggcgtattag tcgtcaggtc ttgtgcagca
    16081 cttccgtaag taagattcat tattttagaa ggagcaatca tctgtccaaa atagtcttga
    16141 tacttaatag tgattggtgt ttgtttgcct gtataggtca ccgtatcgac gttactttct
    16201 agggctgtga aagaaccgtt tgtttgtgca aaagaatagc ccgttactgc tgttggagtg
    16261 ataaccactt tgtcacccac atggattcca gataatgtag tcccgtacgt tccgattttt
    16321 gctgctccac cattgactgt ataagaaaaa gttcctgtcc gattcgcatt gacctgaacc
    16381 gttgctgctt gataggttgg aaaatttgaa acatttccct taccatcaac gatctgccca
    16441 tttttgatcg agtaccccgt gaatggaata tcatttgcta actgtatacc gattgaaaaa
    16501 gtactcatac ctcctccggc aggaagccct ccccatgttg agggtgtaaa agaataactt
    16561 ttatccgcat tgggtgtaac tgaatcgatc gtatttccag cggtagccac ccccatatag
    16621 atactttttg ggaatgtgat agtagtacca tttactgtgg agccaataaa cagattatgg
    16681 atatctggac ggttatcaat aaaagcgatt gctttggtta cgccttgtaa cgcagtttta
    16741 tccgcactca tcgatccgtt aaccgcaaca atgactccat ctttggcata tatcactgta
    16801 tatccatctg gtatggtatg tccgttgaaa ttcgcagtgg ccgcaacagt actaaatgtc
    16861 tggcttctac ctgtttctga ataagctttc tcccctgctg cttttgctgc tgtgatttct
    16921 ttttctgtcg gatcaatcag ttgagtcgag gatgtggttg aggttgtctc gttgttgcta
    16981 gactgattgg tgctttctat ggactgtatt tcagaatagg gtggactatt tgtctcctct
    17041 gtcgtttggt tagcaaaatt tgacgtttct gtataaacgt ttacataaat acttgataag
    17101 ctccctaaga aagtaaaaat caagatgatc gaaatcataa tgggatgtaa gtattttctt
    17161 ttagatacag ctttgagtct agaaacaaaa tgtttttgac atatacgttg gattttattt
    17221 tgagttttct taatcatttt catccctcct ctcaataaaa aatcatcaaa taatccttta
    17281 cacgttattc taaatttaat ttttattatt ttattgatgt atagaaagtt tggggctttt
    17341 tttctctttt tattctaagg ttattttagt cttgtccttt aatacaaaga ttttattttt
    17401 aaataaaaaa tactcttttt ttacgattat tgaaaaaaaa agataaaact tgattaattg
    17461 aagtattgct taaatttgga agctatgagg gaagaataaa agagttagga cgggattatc
    17521 tactattttt ctttgtttta aatatttgtt atctttgaac ataaaagaga aatgtgtcga
    17581 ctgcagtgtt gtgtccctca tcacgaataa acggtgttca attagctgat cttgtattca
    17641 cttaaaaaat ggtaaagtac gagttgctat tccccatttt caattttcta acgctcagga
    17701 caaaatactg ttttcacaac ctcattggaa taaaagcata tatattgttt caagaacgaa
    17761 atcttgttat ctttttaaag ggcatctgtc caaaatctaa ttttaggagg tacgttttgg
    17821 tatttattcg tacaaataaa agagaattat ctttattcat gtaacgcatc caattgattt
    17881 tttcatgtac gctcctggaa cgattttact gacgattgct tatttaactg cgaatcgctc
    17941 attagctttt atcatagcta tccatatttt gaataacgtt cttggctttg tattatagat
    18001 acagatgaca a
//
LOCUS       DAKCAA010000052        17008 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000052 DAKCAA010000000
VERSION     DAKCAA010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.052"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..127)
                     /locus_tag="OUE31_001987"
     CDS             complement(<1..127)
                     /locus_tag="OUE31_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HCU0222977.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(231..542)
                     /locus_tag="OUE31_001988"
     CDS             complement(231..542)
                     /locus_tag="OUE31_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCU0222978.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(544..741)
                     /locus_tag="OUE31_001989"
     CDS             complement(544..741)
                     /locus_tag="OUE31_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HCU0222979.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1135..2862)
                     /locus_tag="OUE31_001990"
     CDS             complement(1135..2862)
                     /locus_tag="OUE31_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HCU0222980.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2855..4048)
                     /locus_tag="OUE31_001991"
     CDS             complement(2855..4048)
                     /locus_tag="OUE31_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HCU0222981.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4235..4879)
                     /locus_tag="OUE31_001992"
     CDS             complement(4235..4879)
                     /locus_tag="OUE31_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCU0222982.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4973..5107)
                     /locus_tag="OUE31_001993"
     CDS             complement(4973..5107)
                     /locus_tag="OUE31_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HCU0222983.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="OUE31_001994"
     CDS             complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="OUE31_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HCU0222984.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7238..7711)
                     /locus_tag="OUE31_001995"
     CDS             complement(7238..7711)
                     /locus_tag="OUE31_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCU0222985.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8112..8336
                     /gene="nrdH"
                     /locus_tag="OUE31_001996"
     CDS             8112..8336
                     /gene="nrdH"
                     /locus_tag="OUE31_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HCU0222986.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8495..10654
                     /gene="nrdE"
                     /locus_tag="OUE31_001997"
     CDS             8495..10654
                     /gene="nrdE"
                     /locus_tag="OUE31_001997"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HCU0222987.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10704..11669
                     /gene="nrdF"
                     /locus_tag="OUE31_001998"
     CDS             10704..11669
                     /gene="nrdF"
                     /locus_tag="OUE31_001998"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HCU0222988.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11758..12897)
                     /locus_tag="OUE31_001999"
     CDS             complement(11758..12897)
                     /locus_tag="OUE31_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCU0222989.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13206..13919)
                     /locus_tag="OUE31_002000"
     CDS             complement(13206..13919)
                     /locus_tag="OUE31_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HCU0222990.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="OUE31_002001"
     CDS             complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="OUE31_002001"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HCU0222991.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15108..16640
                     /locus_tag="OUE31_002002"
     CDS             15108..16640
                     /locus_tag="OUE31_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCU0222992.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16831..>17008)
                     /locus_tag="OUE31_002003"
     CDS             complement(16831..>17008)
                     /locus_tag="OUE31_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0222993.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5279 a         3495 c         2910 g         5324 t
ORIGIN      
        1 atgaaaaaac acattccact aaatttgatg ccggttttcc ttgaggtttt gttccagcac
       61 ctcctttaat ttttttaagc tcttgatctg aacattgttt agcatttagt ctattttttt
      121 cttccattac gattccccct acaaactata aatactttta tgtcactgat tcaatatacc
      181 tatttttcta atcaaaaaat tttgagacat atttaatatt ataagtatca ttaaaattga
      241 gatttatctc cataatctgc tcgatataaa ccatttattc cagcagttct tccaatttca
      301 ctcaaatttc ttattaattc ctcttgatat tcagtgaatc ttattttatt agtataagca
      361 gtaaaatata gataattcac caatctattt attaaaggac tgggatctaa ttcatatttt
      421 tgtttttcta attttaaata taccttttgt aaaacctcaa gaatatcaga atatttagga
      481 tctttactta tagatatatc attatataat tcatgaacaa tttgcttagc attttttttc
      541 attttagcac ttccctggaa ttgctccacc taaaaaacca cctatagaca ttcctgcaat
      601 acaagtagtt gccttggccc aatcgaccgt acatttattt ttagtgcaat acactccatt
      661 tccataatat tttccactat gagtggtacc cccatagata agttgtgtct ctttaataga
      721 caaaattttt aaatgtttca taatctaatc acccctaaat taatgttttt agactattat
      781 tctaacattc attaaatttc aaaaaacaat tccttcttga aacgtagcaa aataattcct
      841 gaataagaat ttaatcactt ttaagtatat aaactatgta tattctttaa tattttttga
      901 gaatgcactt cgtacataat aaactttaat cacattagtc tttcatacct acgatcgatc
      961 tctttgactc gcacccataa attcataata gtttgtcggc gtctttgaac gtttcgaaga
     1021 tgagctacgc attctctttt tttatagaca aaaaagatag agacgaacat ggagcttcca
     1081 aatttggata tttgatccaa ttttggaagc tccatttatt tcgtgtctgt ctttttattt
     1141 tttccagctt tcgactaatt cttggttctc tttgatccag tcttttgctg cttgctgtgg
     1201 atcttttcca ttgttgattt ccaacataac tttttccata tctttttctg accaatggaa
     1261 attgtctaat actttgtaag cttctggctg gtcttctttc aatccttttc gaaccatcgt
     1321 atggatctgc tcttcgcttc ccattccgtt ttcaggatct tctaagtatt tcagatcata
     1381 tttggcaaac atccaatgag gtgtccatcc tgtaactaca attggttcgt gttttttgat
     1441 cgcttgacct agtgcaacgg tcattgctcc tgaagaagat gtctctactt tccagtcttt
     1501 caagttgtca tatttttgga tcgtgttttc agcagccgta actacaccag ctcctggctc
     1561 gattcctatg attttcttac ctgcctgatc ggttaactca tcgatcgaat ttacatccat
     1621 gtaggctggc actgctaaac caacttttgc tcctgtcaaa ttggcaccta ggtcttcgac
     1681 ttgatcttta tattgtgcat attgtgaacc atgagtttta ggtagccaag ctgaaaccat
     1741 ggcatctgac tcgccatttg aaacagattt ccacatgatt gaattatcta atggcgtcat
     1801 cgttacatca tagcccattt gtttcaatac ttcaccgact acatttgttg aagcaacttc
     1861 tgtatcccat tcaacataag ataagttgat acgttttgtt tctttggcag atgaaaaact
     1921 ccctatacca atcgcaccta agatcactac tactacagca ccaatgatca gtccttgacg
     1981 ttttttactt ttctgtgttg ttgctcctgc agctttttta ttgtttggct ggttcaaatg
     2041 ctgtgtaaaa cggtcaatga tgattgctaa gataactaat gcaaccccgt tgacaaatcc
     2101 attcccgact tgtgctcttt gcaatgctga taatacgccg cgtcctaagc cgggtgcacc
     2161 gatcatagag gcaataacga ccattgaaag tgacagcatt gttgtttgat tgatccctgc
     2221 catgatcgta cttttagcta aaggcaattc tagtttgaat agtttttgac gacttgtgct
     2281 cccgaatgaa tcagaagctt ctactaattc tttaggaact tgtcgaatcc ctaaattcgt
     2341 aaaacgaacg gttggtggca gagcaaagat gactgaggca aatacccctg gaaccatccc
     2401 gataccgaaa aatgcaactg ctggaatcaa ataaacgaat cctggcattg tctgcataaa
     2461 gtcaaggatc ggtttgataa tactttgggc tttactgctt tttgccatca agatccctaa
     2521 tggtacccca atgatgatcg agatcacact agataaaaga acaagtgtga cagtattcat
     2581 caaatcattc catagacctt ggttataaat aaaccataga ccgattaatg tgaacaacgt
     2641 aagtcctgga cgtttcttag aaataaagaa agctgctacc gtcaataaca agataaacaa
     2701 aggagctgga atcactaaca gtaaatttgt aatccccgac atcactgcct gtccaatcgt
     2761 ttgtaaaaat gaaaataggc cagaaaaagt tgtcgtaaac cattctgtga tattttctac
     2821 ccagtttgcc actggtaatt gatagttcaa tagattattc atgttcactc acctcgcttg
     2881 tttctgctaa tgcttcaatc acactacctc ggatgacgac accttttaat tttccatcct
     2941 ctacaactgc aagtggagtc ggtgagtcat aaataatatt gaaaatatca cttaccacca
     3001 tgtctttccc aatcaccgtc acattttcat ctaggaagtc gatcaatgga cgtttttgct
     3061 tcctagcttc taacgcttga tctgcagtga tgatcccttt caggtgtctc tttctgtcaa
     3121 cagccatcag catgctgact tcttcattac gcatccttgt caatgcaacg tttggtccat
     3181 cagattcgat attcgtcgtc aatgcaggta ccatgatgtt ttgagccgta agcactttgg
     3241 aacgatcgac ttcttccaca aattcacgta cataatcatt tgctggattg gtcaatattt
     3301 cttcacctgt tccgatctgc atgatttcgc cgtctttcat caaggcgatt ctgtccccaa
     3361 tccgtaaagc ttcattcaaa tcatgggtaa tgaaaataat cgttttttga acattggctt
     3421 gcaggtccag taattcgtct tgcatttctc gccggatcag cggatcaaga gccgagaacg
     3481 cttcgtccat cagcaagatc tcaggatcat ttgctaaagc tctggctagg ccaacccgtt
     3541 gttgcatccc accagataac tgactaggat attggtcttt aaatgaaagc aaactagaat
     3601 tttctaatgc tttttctgct ttttcttgtc gttcttcttt aggtacacca cggacttcta
     3661 acccgtattc tgtattttcc aagatcgttc gatgtggaaa cagaccgaag ttttggaaaa
     3721 ccatattgat tttatgacga cggacttctc gcaattcttc tttgcttaac ttcgatacat
     3781 cttctccatc aatatagata ctgcccgaag ttggctcaat cagacgattc aatagacgga
     3841 tcaatgtgga tttcccactc ccggaaagcc ccatgatcac gaagatttct ccttctttta
     3901 cgtcaaaatt cacgtcatac acaccaaccg ttgcaccggt tttctttaaa atctccgttt
     3961 tcggctggtg atcattcatc atatctaaag cggcttgtgt ctttttacca aatatctttg
     4021 ttaaatgttt tacttctact tttaccaaac aaattctcct tttttatgta aattcatttt
     4081 tctttctgaa aaaagtgacc acactatgtt aacatcatgt agtcactttg tcaaaaatga
     4141 aagaaatttg cttgtccaaa ctgaaaaaaa cttggctaaa tctttgtaaa taaaaggttt
     4201 agccaagtta atattttttt aatatttcac acaatcattc tgcaagctga tgctccgggt
     4261 aaaaaaagtt tgtcatacgc tgtagtgtat attcatttcc aataaaatga acgatgtccc
     4321 ctgccgtaaa tttagcatag gggccaggtg aaacaagcag ttcttcatta tgagaaattg
     4381 cgataactgt ggcgccagtc gcctgccaga tattcaactc gctaattgaa cggtccagat
     4441 gcattgcttt ttctgataaa gataattcaa acggaagtaa aggattcatc ttatgtattc
     4501 gcttcgtttg attgaccagc tgatccaata attgagaaaa atgattcagc tcatcttgtt
     4561 gcttctccac acttgccatg atttctgctt ttgtatcttg gatggattgt acatcttgat
     4621 attgcaatag gaaatctttt gctttttcct tcgaagcaac aaatgcccca cttccatgcc
     4681 gtacttccat gattccaaga tctaccagca cattgatagc cttgcgggta gtctcaggag
     4741 aagcattgta cgtactggca agtgttgagc gggcatggat cttctcaccc actttatatc
     4801 ggttttcaac gatacgttcg gctaaatcaa cagcaatctg ctggtagcgc gggcggacga
     4861 tttttttctt tccagacatt ttctttcctc tttctttttt tactttccct catcttacta
     4921 tgctctagca aaataagcaa aaaaggggag aatagcctct tgcaacgact gatcatcgct
     4981 tgatctgttc cttttttact gggcaagctg tttgacagtc atcacaattc ttaccggatt
     5041 ttaaacgagt atagacaatt gcgcctgcac ttccaaagat taacacactt aataagaatg
     5101 tcgccatcct attcctctcc ttctaatgac aatatagtat aaaactggtt cttggatttt
     5161 ggctgacgga acaaaacata aacgagtcct atcatcagta aaatagcaag atacgtccct
     5221 aacgctacct gtccaccctc caataagtgt cccaactgat aaatcacaaa actaactaaa
     5281 taagctaaac cgcattgata gcctatggcg atccaagtcc atttcttggc attcatttcc
     5341 cgatggatag ccccaattgc cgcaaaacaa ggcgcacaaa gtaaattgaa ggctaacaat
     5401 gaataagctg ctgcgggagt atatgtgtgt tgtagcactt gccagatttc tctgccattt
     5461 tcggatactt ccgcatgacc aaacaaaata ccaaatgtgc caataatatt ttctttagcg
     5521 accaatcctg taatcgctgc gactgttcct tgccagtttc cccaaccaag cggctgaaaa
     5581 acaactgcca ggattcgccc gaaaaaggct aagatacttt ggtcttcaga aacaggttga
     5641 gcataaaaat tataagaaga gctgaaccag atcacgatac tagaaacaaa gataatcgtt
     5701 cctgcttttt taacaaaaga cttgctgcgg tcataggttt gtcttaggac cgctgaccat
     5761 tgaggaaaat gatatgcggg caattccatg ataaaaggag ctgtatctcc agcaaacaaa
     5821 cgtgtttttt tcaagctgat tccagagaaa ataattgcag tcataccaag aaaataggca
     5881 gaaggagcta cccaagattg atgaggaaaa aaggcccctg ctactaaggc aataatcggc
     5941 aactttgcag aacaaggcat gaaggttgtg accatgatcg tcaaacgacg atcttgctcg
     6001 ttttcaatcg tgcgactggc catgacgcct ggcactccac atcctgtagc aatcagcata
     6061 ggaatgaagg attttcctga aagaccgaat ttcctgaaaa gtcgatccat gacaaaagcg
     6121 atcctcgcca tatatccgca gtcttccaga aagctcaagc ataaaaacaa tataatcaat
     6181 tgcggtagaa atcctaacac tgctcccacg cctgcgatga tgccgttcaa gatcagctcc
     6241 tgcatccatc ccgctacttg ccattcagct aacaatctgc caacatgttc tggtaaccat
     6301 gtaccaaaca atgtgtcatt gatccaatct gtccccattg ttcctactgt ttgaatagcc
     6361 agataataga tcagccacat cacaaatgcg aagatcggca aggctaacca acgattcgtt
     6421 gcaatctgat cgattttgtc actcatcgat aattggaaag aatcatttga cacaacacag
     6481 agtgtacata gttgggtaat aaattcataa cgttcattga ccagaatcgt ctcactatcg
     6541 tcgtccaata gtttctctgt taactggatc agttgctcga tctctttttg ctgagaaact
     6601 gctatctcgt aatcctctct taccttctga tctcgttcaa aatatttcat tgcataccag
     6661 cgtttcttgc cgctttgttc tcctagtaca tcttcaattt catgtaaagc tgcttctaaa
     6721 cgtggatcat atgtacaggg aacaggaata gaaggccgct tttttgcaga ctcctgaatc
     6781 ttttcgatta gtttttcgat tccttgcttt ttcaatacgc tgattggtaa aactggtaca
     6841 ccaagaccat aggaaagctt ttctagattg attttttttc cttctttttt gatgacatcc
     6901 atcatattca gaccaatgat cataggaatg tctaaatcca ataactgcgt agttaaataa
     6961 agatttcgtt ctaaattggt agcatcaata atgttgatga tcagttcagg ctgttcctga
     7021 accaaataat ctcttgcaat cacttcttct ggtgtataag gagacaaaga atagatgccg
     7081 ggtaggtcct gaatatgaat gttcggattt tttttcaacg atccttcttt tttttctact
     7141 gttacgcccg gccaattccc tacatattga ttcgaaccag tcaagagatt gaacaagcta
     7201 gttttcccgc tgtttggatt tccgactaac gcgatattca ttctttttcc tccctttgta
     7261 tcaagattag ttcggcctct gactttcgta acgtcagttc ataccctcgc actgtcagtt
     7321 cgattggatc tcccagaggg gctagttttc ggataactat ttttacattt cgcgtcaatc
     7381 ccatatccat taaccgtcgc ttcactgcgc cttgtccgtg gattgctacg acgatcccag
     7441 tctctcctgc ttttaattga tcaagagaag tccagctttc agaggaagca gtctttttat
     7501 tgacaaagat ttgacctagt atttcccgac ttactgccac tcgatgactt tttaccagta
     7561 aaatggcatt gttgcctgat aaattgacga cgacgatttt acttccggca acgatcccga
     7621 tattttgcaa atggcgtttt gttttttctt ctgtttcgat tcgttcgact tgataaacga
     7681 aattctgctt tgcctgcgct aaggtctgca tattgattcc tctcttgtga aataaatcat
     7741 gtattaaaat cattcattat atgttctaat tttcttacgt gttacgcaaa taaatgagaa
     7801 tcattctcac atagaatact ctcggtaatt gagaatgtca attatacttg tgatattatg
     7861 agcgaatctt tagtattgat agataaaaat gagaaaaaaa tatttcttca tagttttcca
     7921 caattttttc tctattaaat ttgctatttt cccacacgat acttgttttc agctcttttt
     7981 tcaaaaacac aaaacttagt attccacagt ttccacaaca caatatgtag tgtttgttgt
     8041 ttgacttttt tactaagagt tttatactat ctattataga taataagaat gtgttagagg
     8101 aggcactcac catgaacgta aaaatctttt ctaaaaataa ttgtatgcaa tgtaagatgg
     8161 tcaaacggtt tttaacagaa aatcaaattg cttttgaaga agtcaatatc gatgaacagc
     8221 ctgaagcagt agactggttg aaagcacaag gattccaaag tgttcctgtc attacttctg
     8281 atgcagaaac agttatcgga ttccgtcctg atcagttgcg taaacttgcc agctaacatg
     8341 actaaaagaa tcaaaacgtg atacatggat ttgaagggct tgagacagca ccagtttttg
     8401 tcgcaaactt ccaaatcctt ttttaaagct taaaaacaat gcaatgattt gcaatcaagc
     8461 atcatcaaat acgaaatgaa ggttgggcgt acgtatgagt cttaaaaatt tacaagatgt
     8521 cagttatttc aagctgaata atgaaatcaa tcggccagtc aatggtcaaa tccctttgaa
     8581 taaggataaa gaagctttag ttgccttttt tgaggaaaat gtcaaaccaa atacgatgac
     8641 ttttccatct attatggaaa aaatcaatta cttgatcgat caagaatata tagaagcaga
     8701 attcattcaa ttgtattcac catcatttat tgaaaagcta tatcaatttt tggacgagca
     8761 acatttttct ttcaaatctt ttatggctgc ttacaaattt tattctcaat atgcgttgaa
     8821 aaccaacgac ggttccgctt atctggaaac ttatgaagat cgagtagcct tcaatgcgct
     8881 ttactttgcg aacggggatg aagaattagc acttgctctt gcagacgaaa tgatccatca
     8941 acgatatcag ccagctacac cttctttctt gaatgctgga cgtaaacgtc ggggcgaatt
     9001 ggtgtcttgt ttcttgactc aagtcactga cgatatgaac tctatcgggc gctcaatcaa
     9061 ctctgctttg caattgtccc gtattggtgg cggcgtaggg attactttat caaatcttcg
     9121 tgaagccggc gctcctatca aaggatatga gggtgctgca agtggtgtcg ttccagtcat
     9181 gaaattattc gaagatagtt tcagctattc taatcaatta ggtcagcgtc aaggagctgg
     9241 cgtggtttat ttgaacgttt tccatccaga cattattgct ttcctttcag caaaaaaaga
     9301 aaatgcagat gaaaagattc gcgtaaaaac tctttctctt ggcgtgatcg tacctgataa
     9361 attttatgaa ttgacacgta aaaacgaaga tatgtattta tttagtccat atagtgtcga
     9421 aaaagaatat ggtgtcccat tctcttatgt aaatattaca gctgagtatg atcatctagt
     9481 tgcaaatcca aacattcgca aacaaaaaat caaagcgcgt gatcttgaaa atgaaatctc
     9541 aaaattacaa caagaatctg gctatcctta cgtaatcaat attgatacag cgaaccgcga
     9601 gaatccaatc gatggcaaga tcatcatgag taatttatgt tcagagattt tacaagttca
     9661 aacgccttct gtgattaacg gcaaacagga atatgaagta ttaggaacag atatctcatg
     9721 taacttaggc tcgacaaata tcgtgaattt gatgcaaagc cctaactttg gtcaatctgt
     9781 gcgtacgatg actcgtgcat tgacatttat tacagatgca tctgatatcg atgtcgtacc
     9841 accgatccaa aacggaaata agctgaatca tacgattgga ttaggtgcca tgggcttaca
     9901 cacttatctt gcaaaagaac aaatggaata tggctcagag gattcattag actttacaaa
     9961 tatttacttc atgctgttga attattggac acttgttgaa agcaacaata tcgctcgtga
    10021 aagaaaacaa gttttccata attttgaaaa atcagcttat gctgacggca cttatttcga
    10081 aaaatacgta actggagaat tccagccaaa atcagaaaaa gtcaaagcat tgtttgaagg
    10141 catttttatc ccaactgctg aagattggaa tgctttgaaa caagcagtaa tgaaagatgg
    10201 actgtatcat caaaatcgct tggcagtagc accaaatggc tcaatttcat atatcaacga
    10261 tacgagtgca agtattcatc ctatcactcg catgatcgaa gaacgccaag agaagaaaat
    10321 cggtaaaatt tattacccag cgccttatct atccaatgag acgattccgt attacacttc
    10381 tgcttatgat atggacatgc gtaaagtaat cgatgtttat gcaacggcac aacaacacgt
    10441 cgatcaaggc atgagtttga ctttattcat gcgttctgaa atcccagaag gcatttatga
    10501 atggaagaca acaacgaagc aaacgacacg tgatttgaat attttaagac attacgcttt
    10561 ccacaaagga atcaaatcca tttattacgt acgtaccttt actgatgatg cagaagaaat
    10621 cggaagcaat caatgtgaaa gctgcgtgat ctaatatcat agatagattc gcttattcat
    10681 attttaatta aaggagcatt ctcatgtcag aaacatatta tgaagcaata aactggaatg
    10741 aaattgaaga tatcattgat aaatccactt gggagaagct gacagagcaa ttttggctag
    10801 atacacgtat cccactttca aatgacctag atgattggcg tacattgtct caattggaaa
    10861 aagatacagt aggacatgta tttggcggtt tgacactgct agatactgtc caatctgaaa
    10921 gtggcatgga tcagttgcgt aaagatgtcc gcactcccca tgaagaagcc gttttgaaca
    10981 atattcaatt catggaatcc gttcatgcca aaagttattc ttctattttt agtacactga
    11041 atacgaaaaa agaaatcgaa gaaatttttg actggacaaa tacgaatcct tatctgcaaa
    11101 aaaaagctga gcgtatcaat gaaatctaca aacacggtac accgctagaa aagaaaattg
    11161 ccagcgtctt tttagaaaca ttcttgttct attcaggttt ttatactcct ctttattatt
    11221 taggaaacaa caaattggct aacgtagcag agatcatcaa actaatcatc cgagatgaat
    11281 ctgtacatgg aacctacatc ggttacaaat tccaattagg attcaacgag ttacctgaag
    11341 cagaacaaga aacgttaaaa gactggatgt acaatcttct ttatgagctt tacgaaaacg
    11401 aagaacgtta tacagaagaa ttatacgatc caatcggctg gacagaagaa gtcaagacat
    11461 tcctacgcta taatgccaac aaagcattga tgaacctagg gatggatcca ctctttccag
    11521 atactgccaa tgatgtcaac ccaatcgtaa tgaacgggat ttcaacaggc acaagcaacc
    11581 atgacttctt ctcacaagtc ggaaacggct atttgttagg tcatgtagaa gcgatgaaag
    11641 acgacgatta tttgattgga ttggaataag gatttatttt aattcaaaaa tttttcgaaa
    11701 aataaaaaga gtttagcgta cagatatttt aaatgtacac tgaactcttt tttatgctta
    11761 ttcacttgtt tcttccagca cttttggact gtctaacttt tccgaaacat gttccattct
    11821 tctcaataaa tagattttcc ggatatttaa tattatcgtc ttaatcactg catagacagg
    11881 tatgcaaatc agcatgccta atattcctgc gacacttcct gctccaatca ataccaagat
    11941 gatcgtcaaa ggatggatat tcattgattt cccaaataac aacggcttga tcaaatttcc
    12001 atctaattgt tggatcacta aaatcgacaa cgccatatac aaagcttgaa atggagagat
    12061 aaacaaaccg acaatgattg ctggtaccgc tccaataaaa gggccgacat acgggataat
    12121 attcgtgatt ccgcaaatga ccgcaagcaa caagctataa ggctgatcga atattctcat
    12181 tgccaaaaag ctcattacac caataatcaa agcatctaag atcgtactgc tgatataggc
    12241 agataatgtt tcgtttaatt cttttaccgt ttggcgtaac tctttacgaa tcgctttcgg
    12301 aaagaagtga gacaacgcat caataaattt gtgcccatcc ttgaacataa atagcaaaat
    12361 aaatggaacg gtaaataaca aaataaaaaa ttgcatcata aatgaaatga tttttgagac
    12421 acttgcagat aaactgacta atatgatatt gaacaaatta ctaagagata aatttgctga
    12481 tgctaattgt tcttccaaat tgaaattttt aaactcttcc cgctgcgcca attcatttaa
    12541 ccatttgctt gtttcatctg catacattgg caagctctgg gtcaattgaa ttgtctgttc
    12601 cattaactga ggcactacat tcatgacagt taaaacaact aaaatgatta cgaccaaaaa
    12661 cgtcaataaa aaaccgaaca ctctcgggat ccgatgcttt tcgagaaaaa caacgattgg
    12721 atcgaacata taatagataa aaccagcaac aagcaatggt aaaaaaattg ccgaaagcat
    12781 tttcaatatt ggactaaaaa tattcggcat ttgtaaaata aagtacacgc cgatgatcgt
    12841 gagtactagc tccactgtcc agaaaaataa ttttgattgt ttaaaacgtg attgcataca
    12901 tctcctccaa ggtcctttga tacttctatt ctatcattta acaaagagtt acgcgctgag
    12961 attttcattt gcttaaaaaa aacaaaaaaa ataaacatat tttaatgagt agacgagtac
    13021 ttaaacaaaa acacggtttg gagtagtgac aaaaattata ctgcagtccc tttttccaaa
    13081 taaacggtgt tcaaaagctt gcatcttcgt aataagccca gccaaacgaa aaatataagg
    13141 aactattttt atttggctgg gcttattact tgatgtagga catctatttt acaacctcag
    13201 atcatttatt gcgcaatact gactaaatgc aactttgtga tatttttgtg tacggacaac
    13261 tcctcgatca catcggcata agtgagccct tttggaagat caatcgtata gatatttttg
    13321 tacactcggt agtcatcaac gaattttacg tcaaaattca catcttcgat tacgatattt
    13381 ttctcttcaa aataatcggt aagaaaatct ttggtttctt ttctatggat aaattggatt
    13441 tctaactttt tagtcgtagg tacatggatc acgcgtttca ctactgtgag tgcaatagca
    13501 atcccgataa aactgatgat cgcaatggaa tagtaaccca tgccgatggc gatccctaat
    13561 ccagcaattg cccataaaga agcggcagtc gtaagtcccg tcaccgattg tttcgtgacg
    13621 atgatcgttc ccgcgcctaa gaaaccgaca ccactcacca cttgagcaat cagccttgct
    13681 tcatctgaac gaatcgttcc agcaagctgt ggatactcta aagcatctct taatgcacca
    13741 ctagcgatct caacttggat caatgcaatg atacatgctc ccatacaaac taaaatatgc
    13801 gtacgcatac ctgctggacg atttttatat tgtcgttcaa aaccgattgc tccgccaaat
    13861 agcatagcga tccctaaacg taaaataatc tctggaattg tcaataccat atcattcatc
    13921 taaacaccct ccagtccaat atatcatgtc tgaaaggagc agacaaaaaa agtgcaattt
    13981 ttacctctta cgaaaaaagg actgtgacaa aatttttgtc atagtccttt ttatgaataa
    14041 acggtgttca atcagctgac cctcggtatt actcaacaaa cggcaaaata tggggagcta
    14101 tttttccttt gtcttctcta atactcaggt caaaacgctg atttcacaac ctctttagcc
    14161 tactattgaa aattacaact tacttgctgc ttcttcatcg atgatcacaa caacattgtc
    14221 gtgattttgc aatacacttg ctggcaaatg attcgttaca ggtccttcaa tcatcccttt
    14281 gattgcatca gctttgcttt cgccaaatgc catcaagacg atttctttac ttttcataat
    14341 tgaaccgatt cccattgaaa cagcttttgt tggtacatct tctgctttat cgaagaatcg
    14401 tttgtttgca ttgattgttg attctgttaa gtcaactact gaagtcgttc cgtcaaatga
    14461 agcaccaggt tcattgaaac cgatatgtcc attttgcccg attcctaaga tttggatatc
    14521 gattggatgt gcatcgatga tttgatcata ctttttgcat gctgcttcca gatcttctgc
    14581 ttttccatct ggtacaaacg tttctttgaa tggtttttta tcaaataatt ggacatccat
    14641 gaaatgacgg tagctttgtt catctgaacc gcctagtcca acgtactcat ctaagtttac
    14701 agaagtcatt tcactgaaat ccaaatcgct tgaagtcatt tctttatata aagtaactgg
    14761 tgtgcttcct gttgccaatc ctaatacttt tgcacctttg ttcatacctt ctttgatgat
    14821 ttcaaatgct ttttttccgc cttcttcagc gttttttaca cgaatgattt ccatagtgat
    14881 tgctccttta tattttggta tagcccaatt atagcattct ttttttcttt ttacaataat
    14941 tagtatagac caaattgcat ttttttcatt ttcttgacaa taaataggaa tccgtgttag
    15001 gtttcataag atggttcaat caaacaatcc atgttgcatg aaaaccaagc aagtgattca
    15061 ctgtggacgc tttatgtctg cagttttttt atgaaaaagg agttattatg agtatactga
    15121 cattaaacaa cattacccag caatttggcg acaaaatcct ctatgaaggt gtcgatctgc
    15181 aattaaatgc tggcgaacat cttgggctga ttggacaaaa cggagccggt aaaagtacat
    15241 tgattaaaat catcactggt gagatcttac cagatgacgg acagatccat tggcaaaaaa
    15301 atattcacaa aggttacctc gatcaatatg tggaagtcga tgaaacatta acaatcgaag
    15361 aatttctaaa aactgcgtac gcaaaagaat acgaaaagga agaaaaaatt gcttttcttt
    15421 accaaacata tagcgagacc ttcgatgatt ccttgctgga aaaagctggg aaactccaaa
    15481 cggaattaga ccaaggagtg ttttatcaaa tcgacacctt agttgctgag atgagcagcg
    15541 ggttggggat cgatgtctta ggtttagatt cactgttgaa aaatctaagt ggtggacaac
    15601 gttcaaaggt gattttagca aaactacttt tagaaaaccc agatgttctg atcttagatg
    15661 aaccaaccaa tcacttagat gatcagcata tccaatggct gacgcagttt cttcaggatt
    15721 ttgacggtgc gtatatcgtg atttcccatg accaagaatt tcttgatcag atcaccaccc
    15781 atatcgcaga catcgagttt ggaaagatta ctaagtatac tggccatcta aaacaagcat
    15841 tgaaacaaaa ggaacaaaat cgcgaaagct atttgcgcca atatcatgct caacaaaaac
    15901 aaatcgaaaa gaccgaagct tatattcgaa aatacaaagc cggttcccga tcaacgatgg
    15961 caaaaagccg acaaaaacaa ttagataaaa tcgaacggct gacgcctcca gcttcagcaa
    16021 gtaaagctgt ctttgatttt ccattctcgc ctattgtcac gacattagca gtggaaacaa
    16081 ctgatttagt catcggatat gatcgaccgc tacttgcacc catcaatttg accatccgct
    16141 ttggtgaaaa tattgccatt cgaggcttca acgggattgg aaaatctact ttattaaaaa
    16201 cactgatcgg tgagattgaa aaaataagtg gcgatttcca cttcccagat aacacaaaaa
    16261 tcaattactt ttcacaagat ctgtactggg aaaatccatt agaaacacca ctacaatatt
    16321 taagcagtca atttccaaaa gcgactatca aagaattacg tcgccaacta gctaaagcag
    16381 ggttagttaa tcaattagca agtgaacctc tcactacatt aagtggtggg gaacaaacta
    16441 aggtgaaact tgcacagttg acaatgaacc aaggtaattt actgattctc gatgaaccga
    16501 cgaaccatat cgatcaagaa acgaaagaaa gcttacaaga cgggatacag aaatttccag
    16561 gaacagtaat catcgtctct catgaacaag aattttatca agatcttgtg caacgagtca
    16621 ttgagattga accaaaataa acgtttgatt gaatagttga aaaaaaggag ctgtgacaaa
    16681 agttttgtca caactccttc ttctgaataa atggtggcca attagctgac cttcggtatt
    16741 agctcaaaaa acggcaaaat atgaggagct atttttattt ggctattctt attacttgat
    16801 gcagaacagc ttttcacaac ctcttttcgt ctatttttta ttttcgagat ttctctttcc
    16861 tttaaaaaca actgtttgaa agaagaacgc acatccttga aaaacaagcc cgctaaccgt
    16921 tacacctaac cagccatact gctgccacat tgtcgtccct agcaatgaac cagccgcacc
    16981 tccaataaag tacataaaca taaataca
//
LOCUS       DAKCAA010000053        16593 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000053 DAKCAA010000000
VERSION     DAKCAA010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.053"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            1..794
                     /locus_tag="OUE31_002004"
                     /pseudo
     CDS             1..794
                     /locus_tag="OUE31_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
     gene            934..1860
                     /gene="cysK"
                     /locus_tag="OUE31_002005"
     CDS             934..1860
                     /gene="cysK"
                     /locus_tag="OUE31_002005"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HCU0222994.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2096..2542
                     /locus_tag="OUE31_002006"
     CDS             2096..2542
                     /locus_tag="OUE31_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCU0222995.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2814..4166
                     /locus_tag="OUE31_002007"
     CDS             2814..4166
                     /locus_tag="OUE31_002007"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HCU0222996.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            4337..4624
                     /locus_tag="OUE31_002008"
     CDS             4337..4624
                     /locus_tag="OUE31_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0222997.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            4850..5293
                     /locus_tag="OUE31_002009"
     CDS             4850..5293
                     /locus_tag="OUE31_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCU0222998.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5299..6483)
                     /locus_tag="OUE31_002010"
     CDS             complement(5299..6483)
                     /locus_tag="OUE31_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HCU0222999.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6751..7449
                     /locus_tag="OUE31_002011"
     CDS             6751..7449
                     /locus_tag="OUE31_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCU0223000.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7456..8133
                     /gene="nth"
                     /locus_tag="OUE31_002012"
     CDS             7456..8133
                     /gene="nth"
                     /locus_tag="OUE31_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HCU0223001.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8259..8792)
                     /locus_tag="OUE31_002013"
     CDS             complement(8259..8792)
                     /locus_tag="OUE31_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223002.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9089..11470)
                     /locus_tag="OUE31_002014"
     CDS             complement(9089..11470)
                     /locus_tag="OUE31_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCU0223003.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11460..12107)
                     /gene="recU"
                     /locus_tag="OUE31_002015"
     CDS             complement(11460..12107)
                     /gene="recU"
                     /locus_tag="OUE31_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HCU0223004.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12171..12710
                     /locus_tag="OUE31_002016"
     CDS             12171..12710
                     /locus_tag="OUE31_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HCU0223005.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12800..13219
                     /gene="gpsB"
                     /locus_tag="OUE31_002017"
     CDS             12800..13219
                     /gene="gpsB"
                     /locus_tag="OUE31_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HCU0223006.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13241..13608
                     /gene="rnpB"
                     /locus_tag="OUE31_002018"
     ncRNA           13241..13608
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="OUE31_002018"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13817..14983
                     /locus_tag="OUE31_002019"
     CDS             13817..14983
                     /locus_tag="OUE31_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HCU0223007.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15029..16525
                     /locus_tag="OUE31_002020"
     CDS             15029..16525
                     /locus_tag="OUE31_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HCU0223008.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
BASE COUNT         5607 a         2858 c         3429 g         4699 t
ORIGIN      
        1 ggaacgagtc ttttagttgg gccgatgatg gttacagcgg taccgcaaca tgttcatgca
       61 gatgaacaag gatctcaaac agttgctgat cctcaagcgt ttatcgatca aatcggctgg
      121 tctgcgtcag aagttgctgc aagtaatgac ttgtatgctt cagtcatgat cgctcaagcg
      181 ttgttggaaa gtgcatatgg cacttccgga ttagctagtg cgccaaatta taatctattc
      241 ggtgtgaaag gaagctataa cggacaggtc gtttatatgg caaccaaaga atatgtaacg
      301 gacaatgggt aacgatgaat gaaccattcc gaaaatattc ttcttattgg gaatccttcc
      361 aagaccatgc gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg
      421 gcgtgtggaa aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt
      481 atgctaccga tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa
      541 cccgttttga tacgccatca acaggttcgg ctaccacaag tacaacaaca acgactacta
      601 cgacgacttc aacgtcatca tcttcaacaa cagatgtaaa tacaaataat ggtcagacat
      661 atacagtcgt gtcaggtgat acgctatggg atattgcaca aaaatttggc atgtctgttg
      721 atgatctaat ggcgaaaaat ggcatgtcta tgtccagtta ttctttatta gttggtcaag
      781 aactaaacgt ttgatttaga taaaaaggca aagaaactac catatatggt atatctttgt
      841 cttttttttg ctagtcaaag acgaatcact cgccataaat gaacagattg tattatgata
      901 agtaagaaga gcaaagacaa ggaggaattg aagatgacag ctatctataa ctcagtcacc
      961 gaattgattg gcaaaacgcc aatcgtcaaa ttaaataaaa tcgtaccaga agattcagca
     1021 gatgtttttg taaagcttga gttttttaat ccaggaggaa gtgtaaaaga tcgtattgct
     1081 ttaagtatga tagaaaaagc agaacacgat ggtctactga aaccaggtga tactatcatt
     1141 gaacctactt ctggaaatac aggaatcgga ttgtcgatgg taggagttgc aaaaggatat
     1201 aaagtaatca tcgtgatgcc tgagacgatg agtatcgaaa gacgtttatt gatgaaaggg
     1261 tacggcgcag agttgatttt gactcctggt gcggatggta tttctggatc aatcagagaa
     1321 gcagaacgtt tggcaaaaga aaacggctac tttttaccat tacaatttga aaatgaagca
     1381 aatcctcttg tgcatgagaa gacgactggt cctgagatac atcaagcatt tggagtaaat
     1441 ggcttggacg cgtttgttgc aggtatcggt acaggaggaa cgatcactgg cgctggccga
     1501 gaattaaaac gtgtgtatcc gaaaatcgaa ttaatcgggg tagaaccagc agaatctgct
     1561 attttagaag ggaaagaagc gggacctcac aaaatccaag gaatcggtac aggttttgtt
     1621 cctaaaacac tggatacttc tgtgtatgat aaagtccttt ctattagtgg agacgaagcg
     1681 atggaaacag ctagagaagt tgggcgaaaa gaagggattt tagtaggcat ctcatctggc
     1741 gctgcaattg ctgccgcgct aaaagtcgca aaagaattag gaaaaggcaa gaaggtatta
     1801 gctgtggttc ccgacaatgg tgaacgttat ttatctacag ccctttacca agagatataa
     1861 ggcacttggt ttttctccag ataggtttat gtaaaaaact tttaaagatg aaaagaacac
     1921 acaaaaattt atgatgagaa aaattatttg aatagagacg taaaatagtg aacgcgactg
     1981 ttttacgtct tttttcatta aaatacaata aaattgaatt ttcttttcat gttaagtgga
     2041 ttttaaaatg taaaaatagt atgataagac gagaataaca acgtggggtg tttacatgga
     2101 aaataagtta gtcgaagagg ttatcgaaaa gttaaaaaaa gagaacattc gaatcacacc
     2161 tcaacggtac gcggttttag aatatttgat tgaacatcat tcccatccaa cggctgatga
     2221 gatttataaa gcacttgaac atcggtttcc aaatatgagt gttgcgactg tttacaataa
     2281 ccttcgctta tttacttcga ttggatttgt tcaagaaatg aagtacggcg atgcttctag
     2341 ccgatttgat ttcagttcaa agcgtcatta tcatgtaatt tgtgaaaact gcggtaagat
     2401 tgttgatttt cattacccag ggcttgaaga tatagaaatg gctgcgagca gactgactga
     2461 ttttgagatt aatgaacatc ggttggaatt gtatggactc tgtccggatt gtaaagagtc
     2521 agcaaaaaag gcgcaaatgt aaaaacagtt tctataagtg ttatacctaa aaaaagctag
     2581 ctgtgtaaaa aaacgctagc ttttttattt ttttgtcttt tattcacaat cttagatatc
     2641 aaagtgaata ttatcacaat aagaatcttg tagatattgg gttcttatgc ttgaaaagga
     2701 atgaaactac aaacaaacct ttgtgaattc acaagcatta aactgttgta tccgttttat
     2761 ttctgttata gtagttttgt cgaaggacaa aatgttaatc ggagggacca taaatgaaag
     2821 tagtagtaat tggctgtact catgcaggta ctgcagctgt aaaaagtatt ttaaaaaatc
     2881 atccagaagc agaagtgaca gtatatgaaa gaaatgacaa tatttctttc ttatcttgcg
     2941 gtatcgcact ttatgtcggc ggagtagtaa aggacccagc aggcttgttc tactcaaatc
     3001 ctgaagaatt atcttcatta ggagcaacag ttaaaatgga acacgatgta acagacgtcg
     3061 atacagaaaa taaaacagta acggcaaaag atctgaaaac aggagaaaca gaaacggttt
     3121 cttatgataa attagtgatg acaactggtt catggcctat tatcccaccg attagtggaa
     3181 tcgatgcgaa aaatgtactc ctatgcaaaa actacaatca agcaaatgaa attattgcac
     3241 aagcgaaaga agcaaaacgt gtagtaattg ttggtggtgg atatatcggt attgaattag
     3301 tagaagcttt tgtcgaatct ggaaaacaag tgacattgat tgatggatta gatcgcatct
     3361 tgaataaata tctagataaa ccattcacag atatcttaga aaaagaattg acagaccgcg
     3421 gtgttactct tgcgctaggc gaaaatgtta ctgaatttat cacagatgaa gaaggaaaag
     3481 tgaaacaagt agctacacca acagatacat ttgatacaga tatggtcatt ttatgtgtgg
     3541 gcttccgtcc aaatacaaaa ctgatcgaag gaaaagtaga tacactgcca aacggggcaa
     3601 tcaaagtgaa tgaatacatg cagacaagtg atccagacat ttttgcagct ggagactctg
     3661 cagtagtcaa ctacaatcca agtggcacgc aaaactatat tcctttggca acaaatgccg
     3721 ttcgtcaagg tttacttgtg ggaaataact tgacagatca taaaatggcg tatcgtggta
     3781 ctcaaggaac ttcaggactt tacctatttg gctggacgat cggttcgaca ggtgtgacca
     3841 aagaaagcgc aactttgaac gatctagaag tccaagcgac tgtatttgaa gataattatc
     3901 gtccagagtt catgccaact actgaaaaag taatgatgga gctagtctat gaaaaaggaa
     3961 cgaatcgtat cgtaggtgct cagttcatgt ccaaatacga cattacacaa tcagcaaata
     4021 ccatgtcttt agctgttcaa aataaaatga ctgtagaaga tctcgcactt tcagatttct
     4081 tcttccaacc acattttgac cgcccatgga attacttgaa cctacttgca caagaagcgc
     4141 taggcgaaat cgaaactgca caataaagaa aaagggttgt gacacaattt tgtcacgacc
     4201 ctctgtcttt ttttgtgaaa agtacaatta gttgtctttc ttcgaatttt ttgtcacaat
     4261 aagcagcaaa gataaagctg ttacataaaa gaacaagcag ctttatttga ttttgaaaag
     4321 aaaggtgaga aagaagatga ataaagaata ttttgtccaa caagatgcat ttttagaaga
     4381 ttataaaagt gcttcgaaga aattaacgat caatattgat gagttggcag atcaagtact
     4441 ctctcagttg aatgaaacgc aagaggaata ttacacgatg ccagcaaatg acgccaaaga
     4501 taatgtttct catcgttttc ctttcagtag acgcatctac tcagatgaaa atgacggcac
     4561 attgaataca gagtacacat atgaaggtca gccatatgtg ctagaaactg atgatgatct
     4621 ttaaagacag tttttgaaaa ggccgctcat ccttaagtga tgacaaaaaa tcatcacaat
     4681 taccgatgac tgtctcttta ctatctttta atcagaaaaa ggggttatga caagctttgt
     4741 caaccccttt ttttcttggt ttcagattgg gttttcctac aaaatatttt tatctttgtt
     4801 gaataggaaa caaaaaaaca atataatgaa agaaaaagaa ggtgtagaaa tggataaaag
     4861 acaactgcta atagaagaat atctggattt agctaatgag attattcatc gtaataaacc
     4921 agaaatggaa aaagaatttg caggatttac tctaaatgaa ctagaagtga ttgaacatat
     4981 cgggaaaatc cctgatccta acgtgacaaa attagcgaat gctagttaca tgactagagg
     5041 agccatcagt aagctaacaa aaaaactgat agctagaggg atcataaaca cttatcaaag
     5101 cgaagagaat aaaaaagaaa tctattttca attgacgcca atcggacaaa aaataaggaa
     5161 tagacacgag caactccatc aaaaatgggt acagcgagat gctactgtat ttgaaaatat
     5221 gtcaaaagaa gaatttgaca cagtatttcg ttttatcggt cgatacagag aatttatacg
     5281 aagtagcaaa tgaagctact attttttatt gtagtgataa taggcaaaaa tcataagcaa
     5341 aaatccgaat accgtcggaa gaaatggtgc tgcagcataa agctgtcctg cgattagcgg
     5401 gccgatgacg cgcgatagag attgtatact ttgggtaccg cccattacaa gaccttgctg
     5461 gttatctgag acagaattgg atagttggcc attgaataca ggagtaaaaa tagaatcacc
     5521 gaaaccataa cagataatcc caaataaaaa caaaatcggc agtagaagaa ttccagataa
     5581 tgtgatgaat agataggcga ggatttcact gaacatccct attcttgtga tctgctgttc
     5641 tgaaaatttt ttgagcaatc gaggcataat gaacaattgc gagacagtat ccaagattcc
     5701 aatcaaagag aagcttaaac caaccaaccc agccttccac tgaaaggcgt caatcgaaaa
     5761 ttgagaaaag atagattgaa gagagccagc tgccaaccaa acagcaaaac ctgctgtcaa
     5821 taaaggaata acggatgaaa tcttgaataa ttgttgtaat tggtgaaaag gtcttacatg
     5881 ggagaaactt aaatctactg aacgtttttt tattggaagg ctttctagca taaatgtgta
     5941 gccataaacg gcatttaaga aagtaaagag tgctccaata aatataggaa cagaattccc
     6001 caactcagct aatagacccc ctataatagg acccagcgtt gttcctatac cgactaaagc
     6061 acccatccat ccaaaaactt tggttctttc attaggttcc gtgatgtcgg caaagtaagc
     6121 atataaggtg gagatttctc ctgccgtcaa tccttcaatg atacgaccaa ggaacaacat
     6181 ccatatcgaa tttcctaaac caaaaagcaa atatccgata cttgatccta ataaactgat
     6241 aataaggatc ggatgacgcc caaaatgatc acttaagcta ccgagaatgg gggcagataa
     6301 gaaggcagct agagcataaa cagacatgag caaagtgata tagaaagctt gctgatgtat
     6361 ggagtgagaa taaggcagcg ttaaaaacgg aagtacagga ctgacgatag taaatcctaa
     6421 tccagtgaat aagacagaga cgtatccaaa aactttagaa tgtttatttg tgaaactgta
     6481 catgtaaaaa ctcctttatg caataatgtt aacttggaaa caaaaatagt gtatagtaat
     6541 tttgtttcct tgtcaacatt ctaaggaaca gcgaaatcta cttaatttat ttattccgaa
     6601 aagtgaagat acgcatcaaa aacatgaaca aacaaaaatc aagtagacga cattgtaaat
     6661 ctgaccgatc agtgaagtaa atagaaaaga aacctgttct tgcttcccat gtttttttta
     6721 cgtatactgt gattgagcgg aggagaaatc atgttgaatt tagaaaatta cttaagcgct
     6781 ggacaaacag tcatatctaa tcttttactt aaaaattatc ataggatcgg tctacaatct
     6841 gaagaatttt tatttgttct acagttgcat atggcacagc ttgaaggaga tactttccct
     6901 gatttgcaga tgattgctat ggatatggga atcaaacaag atcagatttt tcaaatactg
     6961 gatcgtctcg taacaaatgg atttatcaag atagaaacga cgattgtcaa cggtaaaaaa
     7021 gcagatcgat ataatcttta ccccatctat gatctattag gtgagtattt aaaaacacaa
     7081 gaaaaaaaat acgaagaaaa aacacaagaa aaagaaatcc agtcagtgta tcaattattt
     7141 gaacaagaat ttggacgccc gctttcttcg atcgagttcc agcggatcgg acaatggcta
     7201 gaagaagacc attatcagcc ggaaattttg aagctagcac tgcgggaagc cgtattaaat
     7261 caggcttata gttttaatta cgttgaccgc attttgctat cgtgggaaag aaaaaatcta
     7321 cgtacaaaac aacaagtgga agaagaccaa aaacgaagaa aacagcagct tcttcaaaga
     7381 gaagtagaac agtcagctca acaagaagaa ttgccgaaag tctcactgaa aaattggttg
     7441 gaggagtagc ggaatatgtt aagcaaacaa aaaacaatgg aagctctaga aacgatgtat
     7501 ggaatgtttc ccgaagcaca tggagaactc aagcacaata atccatttga gttattgatt
     7561 gcagtgatct taagtgccca ggcgacagat gtatcagtga ataaagcaac gccagatttg
     7621 tttgcctctt ttccgacacc cgatgcgtta gcagaagctt caatcgatga aatcattctt
     7681 aaaataaaaa cgattggttt gtatcgaaat aaagcaaaaa acatcaaagc gtgtgcacag
     7741 cagctgattg aacgtttcga tgggcaagtg ccaacgtcaa gagaagaatt gatgtctctt
     7801 cctggtgtag gcagaaagac agcaaatgtc gtattggggg atgcattcgg gataccagca
     7861 atcgcagtag atacccacgt ggaacgtgtc tcaaaacgcc tgaggatctg caaactagat
     7921 gctacggtca tggaagtaga agaaacactg atgcggaaag taccacaaga attatgggta
     7981 aagacacatc atacactgat tttttttggt agatatcatt gcacggcaag aaatcccaag
     8041 tgcgaggtat gtcctttgct atcaatatgt caagatggga aaaatcggat gcgtctaaaa
     8101 gaaaaggcgc taaaaaagaa accacgcctg tagacgtggt ttctttaatt gcaaataaat
     8161 gtatgaatta tcttgttatt atggagaaaa gctgtttcgt ttatcttttt tgcatgaaaa
     8221 agtaaatgta catactcagt agctaggatg gtaacttatt acaatttatt gcgataaaaa
     8281 taaaagttgt tatttttatt gggaaaatac ccgatgtaga aaataatgcc ttccaatata
     8341 cctataaaat aagtccagta ttccaaagga ttatataaat aagtgacgta tctatctaaa
     8401 ggtgtaataa aaatgataag tgataataaa aaaataccat ttataactaa acataaacta
     8461 atggatttgg gcggtttcag gctcatcaga aaaatataga ttctggtgaa caacaaccat
     8521 aaaaaagtga gaatcattgc atgagagctt ctttccataa attttccttt aagagtagtg
     8581 cttaaaagta cagaaaaaat aataaatgca aggataggag caattaaagt aaatttattt
     8641 aataataaac aaaatttttc agctttttta ttcttggaat aacgaggtat tgttttcgat
     8701 aaaaaaagat ggtgcagaca aattatgata attaagcata ctatcagata actcaaaatg
     8761 aagccttctt tcaaaaaatt attcaaaacc atatattgta ttttttattt gataataaca
     8821 atgggattat taagaagtgg cactaaataa aagactagtg tgtatttagc cgatttaatt
     8881 ataaacaagt aaatggataa agtatatgta atgataaaag aaaaatggat tttctaattt
     8941 ttaagctaaa tgttagatca cacatgtata tgctggatag tcttataaaa aatcatgtaa
     9001 tacagcttgg tacatgattt ttatttgtag ctgtttttta catagacaca aaaaagaaac
     9061 cacgcttgta gacgtggttt cttttttact atctgtttcc agaagctgag gtgctgctgg
     9121 atggtgtatg gtcatttgca gcatccgctc cgctagttgc tggctcactg gaagaagcag
     9181 gaggagcaga tgaagacggt gtcgagcttt cttcggatga agaagaagga accgttgttg
     9241 aagacgctgg ctcgcttgtt tctgctgtcg tgctttcttt tgaggactca gcagttgatt
     9301 cgctttgact agtagagcta gagctttgag tcgttgtctc tgttgttgag cttccaggag
     9361 tctggacata gctggaagat ggaatagttg ttgatggtgt aattgcattc gatctagctg
     9421 tatattgatc tttgtagtac agttcaccgc ccacacgaat taatccgctt ggcatctccc
     9481 agtctgtatt tgtcacgtta gctgaaacat actgcataag ctcgcgataa acatcagagg
     9541 ctacgtgtga cgattctgaa gtgacaggtg tcattttttt attgtaacct gtccacacgg
     9601 aaatcgaata atttggcgta tagcccgcaa ataggatatc tggatacacc ccagaagaaa
     9661 taccaagttt tgcatactcg tcatctgtgt aattggatgt tccggtctta ccggcttgat
     9721 ataacccagc gatttgcgca ttcgtaccag ttccttcagt gatcgtatct tttaaaatgt
     9781 ctgtgatcat ataagctgtt tctggagaca tggctgtttt tccatctggc tcataagttt
     9841 cttctgttcc gtcttggaag acgattttat taacatattg aggtttgtaa taagtccctc
     9901 cattggcgaa agccgcatag gctgctgcca tttttaagga agaagctccg tattttgtcc
     9961 catcttgttc ttccgtatta ctagagatcg cattcgattg atggatcgta ctgtattcga
    10021 tcccaagatt ttttaagaaa gaagccactt tatctgaacc gacttcattg aataatttga
    10081 ctgctggaac attacgggat aagtaaagtg cttggcgtaa agtaatggtg cccatatatt
    10141 gattatccca gtttcctaca ggagtcgaag tcccttcata gttatacggt gcgtcagtaa
    10201 tagtttttcc agtagaatat ttcaaatatt caaaagctgg tccgtaatct gtgacaggtt
    10261 tcatcgtaga accaaaatca cgggaagtat tcactgctaa gttgttgcct aaagttacgt
    10321 cttctgcgat gtgacgtccg ccaatctggg cttttacttt cccggtattg gtgtcgataa
    10381 gggtggaggc aacttgcatc tcgtcgtctg ggtaagagac atactgatcc gtgttgacga
    10441 tatcatatag tttcttttgg gcgtccagat ccaaattcgt ataaatctct aaaccgtctg
    10501 tgtagacatt cttatctgtt ttttcttgta cttcattgat gacttctttg acataattat
    10561 cgacgatctt agtattgtca tcggattgag ttagttcttg cagaccatcc gttaccggta
    10621 cattaacagc ttgatcatat tctgtttgag agattttttc gttttgaagc atcgtataca
    10681 aaacagtatc tcgtcttttc ttcgcctgat ctggataaac ataaggatca taggcggaag
    10741 gggcttgagg catcccagca agcaatgctg tttgcggtaa agaaagttct gataatttct
    10801 taccaaagta catctcagaa gctgtctcca tcccgtacaa gccgtttgac atatacactt
    10861 tatttacgta gtaggtcaag atctcttgtt tcgatttttt ttgttccaat cttacagcca
    10921 tccacgcttc ttgggccttg cgtttcagag tctgatcctc ggcactggtg gagaagaagg
    10981 aaagtttgat caattgctgt gtcaaagtac ttccgccttg cagtccgcca gaggtaaagt
    11041 tagagagggc agaaccgatg atccgaatag ggtcaacccc gatgtgttta taaaaacggc
    11101 gatcttctac cgacacgatc gcatcttcta atgttttcgg taattcattc gcagaaattt
    11161 tttcacgctt ttctgcgcct aaatcttcga atagttcgcc atcttgtgta tatagtttgg
    11221 aagatacggt agcgtctaat tttttatccg tcaattcggg cgcatctttt gcgtaatacc
    11281 agaaaagtcc tacacctgct aaaaagagga tacagaaaaa tgagagtatt cctaaaagga
    11341 tcttgataaa taatcctttt ttatgtgttc cagaggactt tccagaacct ttgccagaat
    11401 tcttcttcac actcttttta ggagtaggct gtttctgtcg tctagagctt ctagtttgtt
    11461 catttgccat tcttgctttc tccttcaata gataatgttg ataaatagaa gtcaaccgcg
    11521 tccaaataag gaatccgcgg agaaatacca gttttgatct ctattcctag ttcttcgatc
    11581 aaagataaag gtagtgattt gcgtcctttt tccttttggg cgtcccagta agcaatcaaa
    11641 tgaacactat tcaaataaaa acagcgcttc aaagacgaaa accataacaa gacaaagcag
    11701 accccatttt gttcgaggca tgctttcata tgttcgattt gatgggcatg gaagttttta
    11761 aagggaaaag atgttttgtt cttggtttct tttgcttcaa agtccaagta aaagcctcga
    11821 tagacgccat tatagtctgt agttgaggct tgggtaaagt aggcttcctt gatcacagca
    11881 gcacttctct taggatagtc tactttcacg atttggatag gggtaggctt tttatggata
    11941 accgccaacc cgcgggaaag ataatattta ttactttcat tgattgcttc ttcaaagcgc
    12001 atcccccgat tgccgaattc agtgatctga tttctttttt cttgaatttt ttcgacggga
    12061 gaggcattct tataataagg ttggccattt ggatagcgca ataccatctt taatcacact
    12121 cctaggccac attatagcaa aaaagcggat agaaagaaaa ggaatctgag atggataagt
    12181 caaaagtaat ctatgtgtct gggtatcgaa gtttcgaact cggtgttttt aaagaaaatg
    12241 atcctaaaat ccaagttgtt aaaaatgttt taaaaaaaga actccatcag ttagcagaag
    12301 aagggctgga atgggtactt gtcagtggga atttgggcgt cgaactatgg gctgtgcaaa
    12361 tagtagcgga attgaaagaa gaatatccgg aactatctct tggtattttg tatccttttt
    12421 ctgattttgg taataactgg aatgaaggga accaagaaaa aaaacaatta gcagaacaat
    12481 tagcagatta tgtcgaagct gttagccatc aaccctacca atcacctagt cagctaaaga
    12541 atcacactcg ttttatactt gagcatacag tgggctgtct gctgatctat gatgaagaat
    12601 tccctggaaa aacgaagtat ttttttgaag atgcacagaa ttaccaagca gatcatccct
    12661 acgaaattcg gctgatcagt atggacgatc ttcaaaattt tagtgaataa tcgatattgt
    12721 gtttgattta tcaacttttt tcctatacaa tgaaaaaggt agaaatgtta ttacgtaaat
    12781 gaaaactaga ggtgtaaata tggcgaattt ggtttatagt cctaaagaca ttttacaaca
    12841 agaattcaaa acaaaaatgc gcggctatga tcccgttgaa gttgatgaat tcttagacaa
    12901 tatcatcaaa gattatgaaa cttacagcaa agaactcctt gctttacaag aagaaaacga
    12961 tcgattgagt gcaaaagtag ctcaattatc taaaactcaa ggagcagctc aaacacgcgt
    13021 gcaacaaaca gaggcaccaa agagcgcagc agtgaccaat tttgatatct taaaacgctt
    13081 gtcaaatctt gaacgtgaag tatttggtaa aaagcttgat caacaagcaa gtgcagtcaa
    13141 accagcacaa cctaatccaa ataactacac aaatgcagac acaagcttag atgataatga
    13201 aaaaacacgt caattttaat ttttgattaa tgaatttgcg gttttcgggt aatcgcggtc
    13261 tgacttgatc aggctgagga aagtccatgc tcgcacaggc tgtgatgcct gtagtgttcg
    13321 tgcttagcga aaccataagc taaggtactc tttggagtaa cggcaggaaa acaagctaag
    13381 gcttcggcta tgcttaagta tccttgaaag tgccacagtg acgaagcggc tggggaaacc
    13441 catccggtgg aacgcggtaa acccctcgag cgagcaaccc aaacaatggt aggggcgctt
    13501 tttgtctgga agaagaacag gacaaaaagg cagtataact gcagatagat ggttaccgct
    13561 ttgttttttc tccctggaaa agcaaagtac agaacatggc ttatagaaaa ccgcaaacat
    13621 cagggaatta ggtcgtgaca aaagtaatgc gttataagaa acaagaaaaa catttgaaag
    13681 ctatttttca atacttcaga tgaatcgttc ttattacaaa acaaactttt gtatcaccgg
    13741 ttattcggaa tttgagtaaa agtgtggggt aggactgatg tcccacctcc tttttttata
    13801 aataaggaga ttgtgtatgg aaaaaaacag gaagttcaac ctcgtcgcaa ctgcggcaag
    13861 cgggctagaa gcactggttg gtaaagaatt aagagatctt ggaatcgaat gccaagttga
    13921 gaacggacgt gcacgttttg aaggaacaat ggaaacgatc gctacagcta atttatggtt
    13981 acgtacagca gatcgagtaa aaatcgtggt tggggaattc gatgcgtata cgtttgatga
    14041 attgtttgaa aacgtaaaag cattgccttg ggaagatttt cttccactag atgcagcttt
    14101 tcctgtagct ggaaaatcga tcaagtcgaa actatatagc acacctgatt gccaagcgat
    14161 cacaaaaaaa gcaatcgttg aacgtctccg tacctattat caccgtccag cttctgtacc
    14221 actgacggaa actggcgcac attttcagtt ggaagtagct ttgctgaaag accatgtgat
    14281 ggtaactctg gatacgacag gaccaagttt attcaaacgt ggttatcgct tagaaaaagg
    14341 tggagcacca ttgaaagaaa acatggcagc agcacttatt atgttgacaa attggcgaaa
    14401 agaccgtcca ttttatgatc ctgtatgtgg ttcaggtacg ctttgtattg aagcagcctt
    14461 aataggccat aatatcgcac caggattcaa tcgtgagttt gcttgcgaat cttgggattg
    14521 gttcagtcaa gaaatcatgg aaaatgttcg atcagcagcc gaagaaaaag cagattatga
    14581 tattgaatta gatattactg gttcagatat caatggacgg atgattgaaa ttgccaaagc
    14641 caatgcagaa gaaatcggat taggctcttc gattaccttt aagcaacaag cagtcaaaga
    14701 cttcaaaacg gataaagaat acggggtcat cgtggctaat ccgccttacg gagaacgtct
    14761 aggagaagaa gaaactgttc ggaaattata taaagaaatg ggcgatgtat tccgtccatt
    14821 aaaaacatgg agtaaatata tcttgactag cgacttagcg tttgaggaat tttacggaca
    14881 aaaagcaacc aaaaaaagaa aattgtacaa tggtgcattg cgtacggatc tattccagta
    14941 ttggggaact cgtccgccta gaaaaaaaga gaaagacgaa taatcttact aattgattca
    15001 ttcaattgga tgtttggagg aatagggaat gaaagaaaaa gagtttttac aagaagtaaa
    15061 agaaatcaat cttctacaac aagctttagg aatcctcgat tgggatacac aaacaggtat
    15121 gcctgaaaaa gctagtgcat accgaagtga agtagacagc tatctttaca gcatttattt
    15181 ttcaaaaaaa atcggtccaa aaatcaaaga agccattcgc tatttttctg aacatccgga
    15241 agaattgtcg gaagttggaa ctgccgtttt tgccaaagta aaagaagagt atgatttgga
    15301 acatcgcgta ccggaagatc ttatgagaaa atatacagct gccgtttctt cagcacacgg
    15361 acaatggcaa aaagctagag aaacacaaca attttctgat tttcaacacg cattgaatca
    15421 aaatattgaa ttaacaaaac agttgatacc ttactggaga aaagatgaaa agacgaatta
    15481 tgatgttttg ctgaatcaat acgaacccgg gatgactgtc gaaatccttg ataaggtatt
    15541 tgatcagctt aaagaaggaa ttctttcgat ccgccgtacg ctccaagaaa aagggactga
    15601 acctgaaaca gactttttaa atcggagaat gacgaaaaaa caacagaaga gatttgtagt
    15661 gaaagtaatc gaacaacttg gttatgattt tagtcgtggt cgtttagatg acactgtcca
    15721 cccatttatg actggaatta atccgaatga tgcacgaatc acgacacgat ggaacgaaac
    15781 agatttcaaa atggctgttt ttggagtgat ccacgaggct ggtcatggta tgtatgaaca
    15841 agacatcgat gataaatatg cgtatacacc ggtttatgaa ggtacatcaa tgggtatcca
    15901 tgaatcacaa tcgttgttta acgagatcat tattggaagt agtcgcagct tctggaaaaa
    15961 gcaatatcct ttctttcaag aatgtgcaga aggaacattc gatgatattc cttttgacaa
    16021 attttatcgt ttattgaacc atacaaaatc aagtttggtt cgtatcgagg cagacagttt
    16081 gacttaccct ctccatatca tcattcgtta tgaaatcgaa aaaatgattt tcaatgaagg
    16141 ggtagatgtt gctgaactac ctgaaatatg gaatcaaaaa tatgaagagt atctgggaat
    16201 acgaccaaca aatgatgtgg aaggcatcct acaagacgtt cattggtcag gtgcaagctt
    16261 tggttatttt ccctcttatg cattagggta catgtatgcg gcacaattac ttcattcttt
    16321 gcagcaagaa atagatgtgg aaaatgttct agcgtcagac gattattctc caatcaaaaa
    16381 ctggatgtca gagcatatcc atcaatatgg tgcatctaga aaaccaaatc aattaatcat
    16441 ggatgcaaca catgaaccgc ttaatccgca atacctgatc gactatatga aagacctgta
    16501 ttttaatgta tatcaggtaa aataaaatac aatttacaaa gatagctgaa attcatctaa
    16561 tctatagatg ttttcagcta tttacttaag aaa
//
LOCUS       DAKCAA010000054        16235 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000054 DAKCAA010000000
VERSION     DAKCAA010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16235
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.054"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(165..779)
                     /locus_tag="OUE31_002021"
     CDS             complement(165..779)
                     /locus_tag="OUE31_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0223009.1"
                     /translation="MELAFKQLEKKDYKKAIQFAIKGMHFDWYTKNKLLLNLYGRYFW
                     YLELNRATQIIALYADDELAGVLLADIKGKSKKHHSFSQKLYVKLFDFLQNAFVKDSK
                     GGYDDTNDELLSDYLKKHSPDGEIVFLAANPDLKIKGIGSKLLKEFERREQGKEVFLF
                     TDSGCTYQFYERRGFERKKEKDNVMKILNKEVDLRCMLYSKIIQ"
     gene            923..1485
                     /locus_tag="OUE31_002022"
                     /pseudo
     CDS             923..1485
                     /locus_tag="OUE31_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364878.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            complement(1596..2570)
                     /gene="lacD"
                     /locus_tag="OUE31_002023"
     CDS             complement(1596..2570)
                     /gene="lacD"
                     /locus_tag="OUE31_002023"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCU0223010.1"
                     /translation="MPLTEKKKTYIRQLSNESGIISALAIDQRGALKKMIGKFQNKSA
                     TDEQIINFKKIISSELTPYASAILLDPEYGLPAAEVRDKNAGLLLAYEKTGYDASTPG
                     RLPDILSIWSVKRLKEQGADACKFLLYYDVDESDDINDQKKAFMERIGSECVAEDLPF
                     FLELVSYDANDPDTSSKEYALKKPHKVNEMMKEFSKPRYGVDVLKVEVPVNMNYVDGY
                     TKNEVAYTKEEAAAYFKEQSETTNLPFIFLSAGVTAELFQETLKFAKEAGSTFNGVLC
                     GRATWANGVEPFVTKGEYAAKEWMQTQGRKNIEELNNVLKETATAIKL"
     gene            complement(2589..3044)
                     /locus_tag="OUE31_002024"
     CDS             complement(2589..3044)
                     /locus_tag="OUE31_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0223011.1"
                     /translation="MTLIKTNKVFMNKNFTTQDEVMNFLADQSIVLSISEDRDAVYEK
                     LMEREEESTTGMMDGFAIPHAKDASIKDADIVIVRLNGKVDWKSLDGEGTDFVIALFI
                     PDSEAGTTHLKFLSQVARLLMHKDVTEGLKQAQSAEEIAELLNQKLEEN"
     gene            complement(3072..4517)
                     /locus_tag="OUE31_002025"
     CDS             complement(3072..4517)
                     /locus_tag="OUE31_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCU0223012.1"
                     /translation="MTTYKIVAATGCPTGIAHTYMAQEALEQAAKRKGVSIKVETHGQ
                     VGIENELTPEEIKNADAVIIAADKDVQAERFAGKRVIDVPVSKGIKDADQLIEDALAG
                     KGSITAENKTVDAAGEKAEMGVAAGIGHSIYKNLMNGVSHMLPFVVAGGVIIAISFAI
                     WGVYSFDPNDPTYNPTAAMLKGVGDAAMGMMVPILAAYIAEGIAKRPGLVVGFVGGLL
                     ANSGGAGFLGGIFAGFLAGYFILLLQKVMKGLPKQLDGLKAIFLYPVIGVLFVGVVMS
                     LLANPMEAVNQGMMNFLAGFQNSNPLILGIIVGCMSAFDMGGPVNKAAYVTGTALLAQ
                     GNHTFMAGVSAACIAPPLITGFAALFFGKYFDTNDRNAGLVNFILGSTHITEGAIPFA
                     AKDPLRVLPTMMLGSSIAAVLTYMFGVQVPAPHGGFLVLPVVTGKVAWVGSILLGSIV
                     GGVILGLIQKRSVEKREAEAAAVEMKEATNN"
     gene            complement(4514..5449)
                     /gene="pfkB"
                     /locus_tag="OUE31_002026"
     CDS             complement(4514..5449)
                     /gene="pfkB"
                     /locus_tag="OUE31_002026"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCU0223013.1"
                     /translation="MSVYTCTLNLAIDLFIETDEMKPSQVNRTNDDDIQANGKGVNVS
                     LIMKQLGIDSTALGFKAGFTGNYIEDYLHQKDISTDFISVPGMTRINVFTQVNKTNEE
                     FKLVNKGPEIPQEQIKTFLNQIQKLQADDYLCVSGSLPRGVSPEILIDISRICFENKV
                     HLIIDSSYPEIIDCLPYQPFLLKPNEEELQSWYNVELSDREGYIHYAERLIADGAKNV
                     LLSLGGEGGIFLNKDIVYSGNSPKGKVVNTACAGDTLLGTFLAGYLKGEQVDINLKKS
                     LAAGSSTAFRKGLTDFSDVAELEKQIEIKEGASKK"
     gene            5617..6375
                     /locus_tag="OUE31_002027"
     CDS             5617..6375
                     /locus_tag="OUE31_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCU0223014.1"
                     /translation="MDTKLSESEKYLWDFIQSHILEIPSYSIVKLSEYANVSTATVVR
                     TMKKKGYEGFTSFKHSLKEKENTNINFAALDKVDEGIKTAILKNEQEVIRTINMVESG
                     NIEDAIQRIKAARRIMIFARGFSELIAQEMMVKFQLTGKYCEMHTDPNIIKNISRKLS
                     KDDIVIFVSLNGETKELTTAAENCYKAEIGTILLTANRHSSLMEHIEIPFVGFKSEGS
                     FFPDYEVRSRLPLSILARILLDSYALRTSGFTQH"
     gene            complement(6870..8069)
                     /locus_tag="OUE31_002028"
     CDS             complement(6870..8069)
                     /locus_tag="OUE31_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0223015.1"
                     /translation="MRDQTSGKMIRFYYTSLHFLYWMMFCSVYGFATLFLIYFKIDPA
                     KIGGILALVNIVSTVLQPFVSQVIIKKRKIPLITVLKTMIAGLGVILLAGVLIPNLPI
                     ITYILGGILVVSMQSFLNALAFEYSNTGYRINFGFSRAGGSFSYAVTSFLLGQLLAIY
                     SAAILPILVIVEAVIFFVILHLLPDVKNQEVFPMTKEQDRSVSLRKKYPFLILLFLGF
                     SFLFTFHTMINSFLAQIFENIHGGSKEVGIALMIAALCELPGMIFFEQLVKKKSSKFW
                     LSVASISFAVRGFMMLLASSILMMEMTHLLQAFSFALFIPASAYLFNQFLADDDRVFG
                     QTMIIIATTLGGVIGNVLGGSLLQHFGVWEMLIFGTGFAVLGALLTILGIRKIPKTGN
                     DSDSLVE"
     gene            complement(8512..9003)
                     /locus_tag="OUE31_002029"
     CDS             complement(8512..9003)
                     /locus_tag="OUE31_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223016.1"
                     /translation="MAEALMITVFLGLLIILQIIDQKKIIVFAQSSPVRKSLSILLTV
                     AILLIFWPEHLTDQIKLVAFASVILINGFLKEGLAKDSVVRFGVLNGNFNRYPQVQVE
                     KLGDDKSFISFYKSKNNSFSMIFDKDQTEMMDVFQELDIHSKITLDQSSEEKRAVVKK
                     DNE"
     gene            complement(9030..10175)
                     /gene="dgoD"
                     /locus_tag="OUE31_002030"
     CDS             complement(9030..10175)
                     /gene="dgoD"
                     /locus_tag="OUE31_002030"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HCU0223017.1"
                     /translation="MKISDVTVYKVKPRWIFVKISTDEGIEGWGEMISGTKTETVVAG
                     AYEIGNRLIGRNPFEIERLFQEMHRSFFRGGPINGTIVSGLEMALWDIKGKAFNVPVY
                     ELLGGAARDKIKVYSWIGGDRPSEVAEQAQDRFDRGFTAVKMNATEELHYIDSYQKVD
                     EVVERVASIRERFGDAMDIGVDFHGRVHKPMAKVLAKALEPFHPMFLEEVVLPENEEH
                     FKEVADSVAVPLATGERLYTRWQFKNLFKQGTVDIIQPDVALCGGILETRKIAAMAEA
                     YDMAVAPHAPYGPVALAATLQVDSCTPNVFIQEQSLGIHYNKGFDLLDFVKNKEVFQY
                     KDGYVDLPSKPGLGLEMDEDKIKEIAQEGLIWTNPQWKNYDGTIAEW"
     gene            complement(10190..11557)
                     /locus_tag="OUE31_002031"
     CDS             complement(10190..11557)
                     /locus_tag="OUE31_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002386123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCU0223018.1"
                     /translation="MKIIMNVFNFFIDAGPTVMLPVIITIIGLIFGLKISRAFKSGLT
                     LGIGFAGIKLILDFMTTNVGPAAKAMVDRTGVKLDALDVGWGSIAAVTWASPIIPILI
                     FAILLVNIVLLILKRTHTLDVDIWNYHHMAIVGVIVYFVTKNVFLGVGASVVMAIATF
                     KISDWSQPMVESFFGIPGVSLPTVSALSSLVIAWPLNWLLDRIPLFRKSKFTIKDAQK
                     YLGFFGDSMIMGLVIGMVIGVLAGYDIKAVLQLGVSMSAVLVLIPKMTSLFMEGLMPI
                     SDAAQKWSQKKFKGTRLFIGLDAAVVVGNPDVITTALIIIPLTIALALVLPGNRVLPF
                     ADLAVVPFRVAMVVALTRGNLLKNIIIGLVVTASLLWCGSATAPMLTAIAKSVGINLG
                     TSSMLISSFAATSMIQSYLVFIAFAYKPIIGIPVLLLAFAGAWYYFDGIKKVNHEMDE
                     PLKAQ"
     gene            complement(11582..11860)
                     /locus_tag="OUE31_002032"
     CDS             complement(11582..11860)
                     /locus_tag="OUE31_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0223019.1"
                     /translation="MKRILVACGNGIATSTVVATKVREYLQQHGIDVSTTQTKLMEVP
                     GKVQDYDLLVTTGQFDGQTGGVPVIKGMPILTGIGADQTMEEILNLLK"
     gene            complement(11879..12337)
                     /locus_tag="OUE31_002033"
     CDS             complement(11879..12337)
                     /locus_tag="OUE31_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0223020.1"
                     /translation="MELYLNEELVFRNVQAKTDSEVLAFLASEMYKKNYVKEEYIQAI
                     QEREKEYPTGLPSTPPGIAIPHANYEMVNKTTLAIATLKDPVLFHNMEDNNEQLPIQI
                     VIMMAIGEPHGQVEMLQKIVGIIQDEPLRQEMIRAGNDTELLELLKKAVF"
     gene            complement(12349..12969)
                     /locus_tag="OUE31_002034"
     CDS             complement(12349..12969)
                     /locus_tag="OUE31_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HCU0223021.1"
                     /translation="MRLADYPKLTVIMRGYTFDQADAILQAMQEFDHQFAVEMTMNTK
                     GALENIHELNQRYGDTTYIGAGTVRTLEQAQACYEAGAKFLLGPHMFTKEMLSYANKK
                     GLLAVPAAMTPSEVDRMFKEGADIVKVFPAAVVTPRFFKDIQAPLGKLPLMGVGGISK
                     ENAKEFFEQGASYLGLGSGMFNKQDIEELNVKNLARSMKELIEAIK"
     gene            complement(12980..15022)
                     /locus_tag="OUE31_002035"
     CDS             complement(12980..15022)
                     /locus_tag="OUE31_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0223022.1"
                     /translation="MNKRIREILKLIIKNPEMKLSTLTSELDLTRRQINYAINQFNEE
                     LKTKNIPLIQRSHSGNITVPIEVIQMISQPDYDIGDDQELVVLTDSERQALIVMTLIA
                     NIDYISLDHLVDAVDVSKTTVMEDIKRTEPFIRNYSLTIRYNRMNGYQLVGSEHRILQ
                     LLSDLVKRFPIFRREMIRRKLAQDVSEEEIVHLIHNMEQMLHLSYSDESVDYLQTSAR
                     FLVSRGIKMSDKHAFFPDDVTDTPEFRMLMILVHETGWSLSKSYMEWFTLLFLTSNIF
                     ESKTTQNYDSDQELRKLISQMVENFQNQTLILIDDREDFERRILSHLRPACFRIRYNL
                     SLGVYSIDSLIKDSNHAILIDLMKELIIPIENWLNKAFPNDELDLLSYYFGYQLSNHN
                     KLNKQRQRAVVVCTNGVMVSKLVRANMEKLFPEIHFLASLSVRDFYKFEADYDLVFTT
                     TPLKSSMLQFMIEPIMTYQQQISLRYRVLSDLGITKVDRAMDELLTIIRKYANITNPV
                     SLREELQYFLIKEDGSTPLDNFNVLPSLTYYLRPSYVQIVEEEMSWERAVEVACRPLL
                     EHQIIDSRFIADCLDQIRQPGYAGYLGMKTCIPHTTVDKGVISDGVSILVCKKPIRFP
                     NGKDVSLILPLSFFDLTKHLRAINQIADIAKDDSLIEQLLIADDEKTVYQLLRQRS"
     gene            complement(15400..>16235)
                     /locus_tag="OUE31_002036"
     CDS             complement(15400..>16235)
                     /locus_tag="OUE31_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCU0223023.1"
                     /translation="LIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAIYMD
                     ATYIPLKRKTLAKEAIHIVVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERGVKN
                     VLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMVYQA
                     SSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIESFN
                     KQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQPME
                     N"
BASE COUNT         5015 a         3446 c         2696 g         5078 t
ORIGIN      
        1 atacaaaaat atttttattg ttggatacag aaatctattt ttaactgggg atatctttgc
       61 cagctaatat ctttgagact acacctatct tcatctaaat ggatcaatta ctcgcttttt
      121 ccattgacct tcgtggtact tctgctttct gatagtaaaa aacattactg aatgatctta
      181 ctatataaca tacagcggag atctacttct ttattaagga tcttcatgac gttatctttt
      241 tcttttttcc gttcgaaacc gcgtcgttca taaaattgat acgtacagcc gctatccgtg
      301 aacagaaata cttcttttcc ttgctctcgg cgttcaaatt cttttaataa tttactaccg
      361 atccccttga tctttaaatc agggttggca gctaaaaaga caatttctcc atctggggaa
      421 tgttttttta aatagtctga aagcaattcg tcattggtgt cgtcataccc gcctttgctg
      481 tctttcacaa atgcattttg taagaaatca aatagtttaa catataactt ttgactaaat
      541 gaatgatgct tttttgattt tcctttgatg tctgctaata aaacacctgc caactcatca
      601 tccgcatata aagcaatgat ttgtgtcgcg cgattcaatt ctagatacca aaagtatctt
      661 ccataaagat tcaaaaggag tttgttcttg gtataccaat caaagtgcat acctttaatc
      721 gcgaattgaa tggctttttt gtagtctttc ttttccagtt gcttaaaggc taattccatc
      781 acttattctc ctattcttta aatattgata tgctatactt atattataat agacaaggtg
      841 tcggttatct atgttcagat agcggtgaaa ttgtcggata accgacacaa ttccttgatt
      901 atgttgatta ggaggctgca aaatgaaaaa agaggatcgc cgcgtcaaaa aaacagaaaa
      961 agcgttagca gaagcattat caaaattatt agtagataaa aaaattcaaa acatcaccat
     1021 ccgtgaactg accgaaactg ctgatcttca ccgttcgaca ttttatacac attatacgga
     1081 tatctatgat ctttatgaaa aactggaaaa tagctttttc caagacttgg atgaaatcat
     1141 ttcctacgat acgacacata gctacgagga tctatacgct caattgatcg actatgtcta
     1201 tacgaatacg ttcgtataca agttattcgt catcaaccac ggagatatcc aatttcaaaa
     1261 gagattaaat aatctgatcg aagaaaatta tttaaaaatc tggctacaag aagacaaaaa
     1321 aaaccgtgat cacagaagaa atgcgttact tcaccatcta ccatatccaa gggtgcctct
     1381 ccgttttaaa tcattgggta gaaaagcaat tttgcatact ctaagaaaaa aatgctgacc
     1441 ttcttgcgct tattgaacga caacatagaa cctatcatgc cttaaaaaca aacgaaaaag
     1501 gaagcgtcgg gacgcttcca attctttatt taaaagctca aattgattat taaaaatcat
     1561 taggttacaa acttaaggtt atagttaaag ctttcttaca atttaatagc tgttgctgtt
     1621 tctttcaaaa cattattcag ctcttcgatg ttcttgcgtc cttgtgtctg catccattct
     1681 ttggcagcat attcaccttt agtaacgaat ggttctacac cattcgccca agttgcgcgc
     1741 ccacagagta ccccattgaa tgtagagcca gcctcttttg caaatttcaa ggtttcttgg
     1801 aacaattcag cagttactcc tgcgctcaag aaaataaatg gcaggttggt agtctcggat
     1861 tgttctttga aataagcagc agcttcttct ttggtataag caacttcatt tttagtgtaa
     1921 ccatccacat agttcatatt aacaggaact tccactttca aaacgtcaac tccatagcga
     1981 ggcttagaaa attccttcat catttcattt actttatgcg gttttttcaa ggcatattcc
     2041 ttcgaagaag tatcaggatc gttggcatca taagaaacca attctaagaa aaatggcaaa
     2101 tcttcagcaa cacattcaga accaatccgc tccataaacg ccttcttttg gtcattgatg
     2161 tcatcagatt catctacatc gtagtataac aagaacttac aagcatcggc cccttgctcc
     2221 tttagacgtt ttacagacca aatagataaa atatccggta aacgtcctgg agttgaagca
     2281 tcgtaaccag ttttttcata ggccaacaac agaccagcat ttttatcgcg aacttcggct
     2341 gccggcaacc catattctgg atctaataag attgctgaag catatggagt caattcagaa
     2401 gaaatgattt ttttgaaatt gatgatttgt tcatcggttg ctgatttatt ttgaaattta
     2461 ccgatcattt ttttcaaggc accacgttga tcgattgcta acgcactgat gatgccactt
     2521 tcattactta gttgacgaat ataagttttc tttttttctg ttaaaggcat gatttcacta
     2581 cttccttttt agttttcttc taatttttgg tttaaaagtt cagctatttc ttcagcagac
     2641 tgggcttgtt tcagaccttc tgtcacatct ttgtgcatca aaagtctggc tacctgagat
     2701 aaaaatttta gatgggttgt tccagcctct gaatctggaa taaacagagc gattacaaaa
     2761 tccgttcctt ctccatctaa acttttccaa tcgaccttac cgtttaaccg aacaatcaca
     2821 atatcggcat ccttgatact agcatctttg gcatgaggga tggcaaaacc atccatcata
     2881 ccagtcgtgc tttcttcttc tctttccatc aatttttcgt aaactgcatc tcggtcttca
     2941 ctaatgctca agacaattga ctgatctgca aggaagttca ttacctcatc ttgcgtcgta
     3001 aaatttttat tcataaaaac tttatttgtt ttgatcaaag tcatttgaaa tccttctttc
     3061 tagaataacc tttagttgtt ggttgcttct ttcatttcaa cagcagctgc ttctgcttca
     3121 cgtttttcta cactacgttt ttggatcaac cctaaaatta ctccgccaac gattgaacca
     3181 agtaaaatcg accctaccca tgcaacctta ccagtaacaa caggtaatac tagaaaacct
     3241 ccatgaggtg cgggaacttg gacaccaaac atatatgtca gtacagcagc aattgatgaa
     3301 cctagcatca tagttggcag aacacgcagc ggatctttag ccgcaaatgg aattgctcct
     3361 tcggtaatgt gcgttgagcc caagataaag ttgactaaac cagcgttgcg atcattcgtg
     3421 tcgaaatatt ttccaaaaaa cagtgcggca aatccagtaa tcaatggggg cgcgatacaa
     3481 gctgccgaaa cccctgccat aaatgtatgg ttaccttgtg ccaacaacgc agtccctgta
     3541 acataagccg ctttattgac tggacctccc atatcaaatg ctgacataca gccaacgata
     3601 atccctaaaa ttaatggatt agaattttgg aatcctgcca agaaattcat cattccttgg
     3661 ttgactgctt ccattggatt tgctaataaa gacatgacta caccaacaaa caagacaccg
     3721 atcaccggat ataagaagat cgccttcaga ccatccaatt gtttaggcaa gcctttcatg
     3781 accttttgca atagtaagat aaagtagcct gctaagaaac ctgcaaaaat tccgcctaag
     3841 aaaccggctc cgccagaatt ggctaacagt ccgccaacaa acccaacaac caaaccagga
     3901 cgtttagcga ttccttcagc gatataagct gctaaaatag gaaccatcat tcccattgcc
     3961 gcatcaccaa caccctttaa catagcggca gtcggattgt aagtaggatc attgggatca
     4021 aaagagtaca caccccagat ggcaaacgaa attgcaataa ttaccccacc tgccactaca
     4081 aacggcagca tatgagaaac accgttcatg agatttttat aaatactgtg accaatgcct
     4141 gctgcaaccc ccatctccgc tttctcacca gcagcgtcaa ctgttttgtt ttctgcagtg
     4201 attgaacctt taccagccaa cgcatcttcg atcaattggt cagcatcttt aatccccttg
     4261 ctgacaggca catcgattac acgcttacct gcgaaacgtt ctgcttgaac atctttgtca
     4321 gctgcaatga ttacagcgtc agcgtttttt atttcttctg gtgttaattc attctctatc
     4381 cctacttgac catgggtttc aactttgata gatacccctt tgcgcttagc tgcctgctcc
     4441 aatgcttctt gagccatata agtgtgggca attcctgttg gacatcctgt tgcggcaaca
     4501 attttgtaag ttgtcatttt ttactcgctc cctctttgat ttcgatttgt ttttccaact
     4561 ctgcaacatc cgaaaaatct gttaatcctt tacgaaaagc ggttgaactt ccagctgcta
     4621 aacttttctt caaattaata tctacctgtt caccttttaa atatcctgca agaaatgttc
     4681 ccaacaaagt gtcaccagca cacgctgtat tgactacttt acctttagga gaattcccag
     4741 aataaacgat atccttattt aaaaatattc ctccctctcc tcctagagaa aggagaacat
     4801 ttttcgctcc atcggcaatc aagcgttcag cataatgaat atatccttca cgatcactaa
     4861 gctcgacatt ataccaagat tgcaattcct cctcgtttgg ttttaataag aacggctgat
     4921 acggcagaca atcaattatt tccggatagc ttgaatcaat aatcagatgg accttatttt
     4981 caaaacaaat acgactgata tcaataagaa tttcgggtga gacccctcgc ggcaaactgc
     5041 cagaaacaca caaataatcg tcagcttgca gcttttgtat ttgatttaga aaagttttga
     5101 tttgttcctg aggaatctca ggtcctttat taaccaattt gaattcttca ttggttttat
     5161 taacttgtgt aaaaacgttg attctagtca ttcccggtac gctaataaaa tcagtgctaa
     5221 tatctttttg atgcaaataa tcctcaatat aattcccggt aaaacctgct ttaaatccta
     5281 aagctgtact atcgatacct aattgcttca tgatcaatga aacattcaca ccttttccat
     5341 tagcttgtat atcatcatcg tttgttcgat tgacttggga tggtttcatt tcatctgttt
     5401 cgataaaaag gtcgattgcc aagtttaaag tacatgtata aactgacatt tacgctcctc
     5461 ctttcttaca tattcattat gtatcaagat cgaatgtaaa tgttttcata aatgactaaa
     5521 ttcattgaaa acttttacaa aatatattaa ataaacttga agtaaaggaa actcccgctt
     5581 tacaatagaa ttatcctaac taatcggagg caaaatatgg atacaaaatt aagtgaatcg
     5641 gagaaatatc tctgggattt tattcaaagt cacatactcg aaatcccctc ctattccatt
     5701 gtaaaactaa gtgaatatgc caacgtttca acagcaaccg tcgttcgtac tatgaagaaa
     5761 aaaggatatg aggggtttac gtcttttaaa cattcgttaa aagaaaaaga aaatacaaat
     5821 atcaattttg ccgctcttga taaagttgat gaaggaataa agactgctat tcttaaaaat
     5881 gagcaagagg taatccgcac catcaatatg gtagaaagcg ggaatattga agatgctatt
     5941 caacgaatca aggctgctag aagaatcatg atttttgccc gaggtttttc agaattgatt
     6001 gctcaggaaa tgatggtcaa atttcaactt accggtaaat attgtgagat gcatactgat
     6061 cccaatatca taaaaaacat tagtagaaaa ttatccaaag atgacatcgt gatctttgtt
     6121 tcactaaacg gtgaaacaaa ggaattgact accgcagctg aaaactgtta taaagctgag
     6181 atcgggacaa ttttgcttac tgctaatcgt cattcaagtt tgatggaaca tatcgagatt
     6241 ccttttgttg gctttaaatc agaaggctcc ttcttcccag attatgaggt acgctccaga
     6301 cttccacttt ctatactggc tagaatctta cttgactcct atgcactgcg aacatcagga
     6361 ttcacacagc actaactcta tatctgtaag actgtaccta aaatatatct gtgtgaatta
     6421 actaaggttg tctagaaaaa tatttaatcg ctatttgtat tctcgtgctt tctatcattg
     6481 ctccttctat aacttcttag tttcaagata gaatagtgca ttgagactac caggactact
     6541 tacgcaaata tataataata agaatgtgat aagcagttcg aagttcctgt ctaatatttc
     6601 ttgttaatta ttatcaattt ccaacaattc tagaattata atacgcaaaa aaaggagacc
     6661 gtctaaccgt ctccttatag tttattattc agattacaat cagttatcta aaatgttaca
     6721 gaagttttat tagggatatt ttcttatctt tttagatgag gtttctcaat tatttagaaa
     6781 tgcttactta agttattctc gttttttgta attacgccaa taatcactat atgttattta
     6841 tataaaacta gtatctaagt atttttatgc tactcaacaa gagaatcact atcgtttcct
     6901 gtcttcggta tttttcgaat gcccaaaata gttaataaag cacctagcac cgcaaaacca
     6961 gtaccgaaaa tcagcatctc ccatacaccg aaatgctgca gcagactgcc gcccaagaca
     7021 tttcctatca ccccaccaag agttgtggcg atgatgatca tcgtttgtcc aaatacacga
     7081 tcatcatccg ccagaaattg attgaacaaa taagccgaag ctggaataaa caaagcgaaa
     7141 ctgaaggctt gtaggagatg cgtcatttcc atcatcagga tcgaactggc cagcagcatc
     7201 atgaatcctc tgacagcaaa tgaaatactg gcaacagaca gccaaaattt gctggatttc
     7261 tttttgacaa gctgttcaaa aaagatcatt cccggtaatt cgcataaagc ggcgatcatc
     7321 aatgcgatgc caacttcttt actgccgccg tggatatttt caaagatctg tgccaaaaag
     7381 ctgttgatca tggtgtggaa agtaaaaaga aaactgaaac ctaaaaataa caaaatcagg
     7441 aaaggatatt tttttctcaa agaaactgag cgatcctgtt cttttgtcat aggaaaaact
     7501 tcttgatttt ttacatccgg cagcagatgc aaaataacga aaaatatcac tgcttcaact
     7561 ataaccaaga ttggcaaaat cgcggcagaa taaatcgcta acagctgtcc cagtaaaaaa
     7621 gaagttacag cataagaaaa tgaaccacca gctcttgaaa agccaaagtt gatcctgtag
     7681 ccggtatttg aatactcaaa tgccagcgca ttgagaaatg attgcataga aactactaaa
     7741 atcccaccca agatataagt aatgatcggc aaattcggaa tcaatacccc agctaagaga
     7801 atcactccta atcctgctat catcgtcttc agcacggtga tcagtgggat ctttcttttc
     7861 ttgatgatca cttgactgac aaaaggctga agcaccgttg aaacaatatt gaccaatgct
     7921 aagatccctc cgattttagc tggatcaatc ttgaaataaa tcaaaaacaa tgtcgcaaac
     7981 ccatagacag aacaaaacat catccaataa agaaaatgca aacttgtata ataaaaacga
     8041 atcatttttc cgcttgtttg atcgcgcaca catctcccac cttattggtt tttctttagc
     8101 aatttactat agcatacttg taggggtttt actattttta aaagtggtga agaactatgg
     8161 aaattagggt agattacaat atgcgttgat caattaaaac atctgttaat aaagacggaa
     8221 aaaagatcat agaagcatcg tactttttta gcatactagc ttggtcattt ttttctggaa
     8281 ttgaagaaaa tatatatatt ctaaaaacta tccatcatct cttagattac gagctttttt
     8341 tgctgcaaag gaagttaaaa aaagcaggga tcgagtaatc gattcctgct atatcttgta
     8401 ccaatatatt tctttccaaa acttaatata cattgtatac ttcaatcaat atgattcatt
     8461 aaaacaagtt tcattattcg tgataaagaa atcataattt cggtagtaga atcattcatt
     8521 atcttttttt acaactgctc ttttttcttc cgaactttga tctaaagtaa ttttggaatg
     8581 gatatcaagt tcttgaaaga catccatcat ttcagtttga tctttatcaa aaatcattga
     8641 aaaagaatta ttcttgcttt tgtaaaatga aataaatgat ttatcgtcac ctagtttttc
     8701 tacttggact tgaggatatc gattaaagtt accgttcaat actccaaatc taacaacaga
     8761 atcttttgct agaccctcct tcaaaaaacc attgatcaaa atgacagaag caaaagcaac
     8821 cagtttaatc tgatcagtca gatgttccgg ccagaaaatc aacaggatgg cgactgtcag
     8881 taaaatactc aaactcttcc ttacaggact actctgagca aacacgataa ttttcttttg
     8941 atcgattatt tgcaaaataa tcagcagtcc taaaaaaact gtgatcataa gtgcttctgc
     9001 catctttcat catcctttat tttcatttat caccactcag cgatcgtacc gtcataattt
     9061 ttccattgcg gattggtcca aatcaaacct tcttgtgcaa tttctttgat tttgtcttca
     9121 tccatttcca agcccagacc tggttttgaa ggtagatcta cgtagccgtc tttatattgg
     9181 aaaacttctt tgttcttcac aaaatctaac agatcaaaac ctttgttata gtggatccct
     9241 aagctttgtt cttggataaa gacgtttggc gtacatgagt ctacttgcag agttgctgct
     9301 agtgcaacag gaccatatgg cgcatgaggc gcaacagcca tgtcgtaagc ttccgccatc
     9361 gctgcgattt tacgggtttc caagattccc ccacaaagag ccacatctgg ttggataata
     9421 tcaacagtac cttgtttaaa gaggttcttg aattgccaac gagtgtacaa gcgttcacca
     9481 gtagctaatg gtacagccac agaatcagct acttctttaa agtgttcttc attttcaggt
     9541 aaaacgactt cttccaaaaa cattggatgg aatggctcca aagcttttgc tagcactttt
     9601 gccatcggtt tatggacccg tccatgaaaa tcaacaccaa tatccattgc atcaccaaaa
     9661 cgttcgcgaa tagacgcaac tcgttccacc acttcatcaa ctttttggta ggaatcgata
     9721 taatgcagct cttctgtcgc gttcatcttg acggccgtaa agccccgatc aaaccgatct
     9781 tgtgcttgtt ctgcaacttc acttggtcga tctccaccaa tccaagaata aaccttgatt
     9841 ttatcacgtg ctgcaccgcc caataattca taaaccggaa cattaaacgc ttttcctttg
     9901 atatcccaca gagccatttc taaacccgaa acgatggttc cattaatagg accgcctcgg
     9961 aagaaagatc gatgcatttc ttggaagagg cgctcgattt caaacggatt acgtccaatc
    10021 agccggtttc ctatctcata agctccagca acaaccgttt ctgttttagt tcctgagatc
    10081 atttctcccc agccttcgat tccttcgtca gtcgagatct taacaaaaat ccatcttggt
    10141 tttactttat acactgtgac atctgaaatt ttcaatttaa accctcctac tattgtgcct
    10201 tcaatggttc atccatttca tgattaactt ttttgatacc atcgaagtaa taccatgcgc
    10261 ccgcaaaggc taataacaac actggaatac cgatgattgg tttgtaagca aatgcgataa
    10321 ataccaaata actttggatc atggaagtcg cagcaaatga tgagattaac attgaagaag
    10381 ttcctaagtt aataccaacc gatttggcaa ttgctgtcag cattggcgca gtagctgacc
    10441 cacaccatag caatgaagct gtcacaacta agccaataat gatatttttt aataaattac
    10501 cacgagtcaa ggcaacgacc attgccacgc ggaaaggaac aaccgctaaa tctgcgaatg
    10561 gtaacacacg gtttcctggc aatactaaag ctaatgcaat cgttagtgga ataatgatca
    10621 atgctgttgt gataacatct ggattaccta caacaactgc agcatccaat ccgataaata
    10681 aacgtgtacc tttgaatttt ttttgtgacc atttttgtgc agcatctgaa attggcatca
    10741 atccttccat aaataatgaa gtcatcttag gaatcaaaac caaaacagct gacatgctga
    10801 cacctaattg taaaaccgct ttgatatcat agccggctaa aacaccaatc accatcccaa
    10861 taactaaccc catgatcata gaatcaccaa aaaatcccaa atatttttgt gcatctttga
    10921 tggtgaattt tgattttctg aataacggga tacgatccag cagccaattt aacggccaag
    10981 caataaccag tgatgaaagc gcagaaacag ttggtaaaga aacaccaggg attccgaaga
    11041 aactttctac catcggttgc gaccagtctg aaatcttaaa agtcgcaatt gccatcacta
    11101 ctgatgcacc tacacctaag aagacattct tagtcacaaa atacactata acaccaacga
    11161 ttgccatatg gtgatagttc cagatatcaa catccagcgt atgtgtacgt ttcaaaatca
    11221 gcaaaacgat attgaccaat agaatggcaa aaatcaagat tggaatgatt ggcgatgccc
    11281 aagtaacagc cgcaatcgaa ccccagccaa catccaaagc atctagttta acaccagttc
    11341 gatcaaccat cgccttggca gctggtccaa cattggtcgt cataaagtcc aatatcaact
    11401 tgatcccggc aaaaccgata cctaatgtca aacctgattt aaaagcacga gaaatcttta
    11461 acccaaaaat caaaccaata atcgtgatga tgactggcaa cataactgtt ggtccagcat
    11521 caataaagaa gttaaagacg ttcataatga ttttcatttt ttcagctcct ttgatcagct
    11581 attatttcag taagttcaaa atctcttcca ttgtctgatc ggcaccgata cctgttaaaa
    11641 tcggcatccc tttgattact ggtacaccac ctgtttgacc atcaaattga ccagtcgtca
    11701 ccaatagatc atagtcttga acttttcctg gaacttccat caattttgtt tgagtcgttg
    11761 aaacatcaat gccatgttgt tgcaaatact ctctaacttt tgttgctact actgttgaag
    11821 tggcgatacc atttccgcat gctactaaaa ttcgtttcat tatgatttcc tccttatatt
    11881 aaaaaaccgc tttctttaat agttctaata attcagtatc attgcctgct ctgatcattt
    11941 cttgccgcag tggctcatct tgtatgattc caacaatttt ttgtaacatt tcaacttgcc
    12001 catgtggttc cccaatcgcc atcatgatca caatttggat tggtaactgc tcattgttat
    12061 cttccatatt atgaaatagg accggatctt taagagtcgc aattgctaaa gttgttttat
    12121 tgaccatttc atagtttgca tggggaattg cgattcctgg tggtgttgat ggtaatccag
    12181 tagggtattc tttttcccgt tcttggattg cttgaatata ttcctccttc acgtagtttt
    12241 ttttgtacat ctcgcttgct aaaaacgcta agacttcact atctgttttt gcttgaacat
    12301 ttcgaaaaac gagttcctca ttcaaataaa gttccaaagt cctcactcct atttaatagc
    12361 ctcaattaat tctttcatcg aacgtgctaa gtttttaaca tttagctctt cgatgtcttg
    12421 cttgttgaac ataccggaac caagacctaa atagctagca ccttgttcaa aaaactcttt
    12481 cgcattctcc ttactgattc caccaacccc cattagtggt aacttaccta aaggtgcttg
    12541 aatatccttg aaaaaacgtg gagtaacaac cgctgcagga aatactttta caatatcagc
    12601 tccttcttta aacatacggt cgacttctga aggagtcatt gcggcaggta ccgccaataa
    12661 tcctttctta ttggcgtaag acaacatttc ttttgtgaac atatgtggtc ctaataaaaa
    12721 ttttgcacca gcctcatagc aggcttgggc ttgttctaat gtccttaccg tcccagcgcc
    12781 gatataagtc gtgtcaccat aacgttgatt tagttcatgt atattttcaa gagctccttt
    12841 tgtgttcatt gtcatctcta cggcaaattg atggtcaaat tcctgcattg cttgtaaaat
    12901 agcatctgcc tgatcaaaag tataaccacg catgatcact gtcaatttag gataatctgc
    12961 tagtctcatg ttttcctcct taagatcttt gtcttaatag ttgataaact gtcttttcgt
    13021 catcagcaat caataactgc tcaatcaatg aatcatcttt ggcgatatca gcgatttgat
    13081 tgatggctcg cagatgcttc gttaaatcaa aaaatgaaag cggcaaaatc aagctgacat
    13141 ctttaccatt aggaaatcgt atcggctttt tacaaactaa aatgctgaca ccgtcactga
    13201 ttacaccttt atcgaccgtt gtatggggaa tgcaagtctt cattcccaag taacctgcat
    13261 atcccggttg tctgatttga tccaagcaat cagcgataaa acgcgagtca atgatttgat
    13321 gttccaataa cggtcggcaa gccacctcca ctgctcgttc ccaagacatc tcttcttcaa
    13381 cgatttgtac ataactcggc cgcaagtaat aagtcaatga aggcaataca ttgaagttgt
    13441 ccagcggcgt gcttccatct tccttgatca aaaagtactg cagttcttct cgcaacgaaa
    13501 ctggattggt gatatttgca tatttcctaa tgattgttaa caattcatcc attgctcgat
    13561 caaccttagt aattcctaaa tcactcaaaa ctcgatatcg taaactgatt tgttgctgat
    13621 atgtcatgat tggctcgatc ataaactgca gcatagaact ttttagtggc gtcgtagtaa
    13681 agaccagatc ataatcagct tcaaatttgt agaaatcacg cacagatagg gaagctaaaa
    13741 aatggatctc tggaaaaagt ttttccatat tggctcgtac taactttgag accatgacac
    13801 cattagtaca aacaactaca gccctttgtc gttgcttatt caatttatta tgattactta
    13861 attgatagcc aaagtaatag gataaaagat ctaattcatc atttggaaag gccttattta
    13921 gccaattctc aataggaata atcaattctt tcatcaaatc aatcaaaatc gcatgattac
    13981 tatccttgat cagactatct attgaataaa ctcctaaact caagttatag cgtattcgaa
    14041 aacaggctgg acgcagatga ctcagtatcc tacgttcaaa gtcttctcgg tcatcgatca
    14101 aaatcaacgt ttgattttgg aaattttcaa ccatttggct gatcaatttt cgcaattctt
    14161 gatccgaatc ataattttga gtagttttgc tctcaaaaat attggaagtt aaaaataata
    14221 acgtgaacca ctccatataa cttttggata gactccaacc tgtttcatgt accaagatca
    14281 tcagcattcg gaattcagga gtatccgtca catcatcggg aaaaaacgcg tgcttatctg
    14341 acatcttgat cccacggctt actaaaaatc tcgctgatgt ctgcaaatag tctaccgact
    14401 catcagaata actaagatgc aacatttgtt ccatgttatg gatcaaatgg acgatttctt
    14461 cttcagaaac atcttgtgcc aattttctgc gaatcatttc tcggcgaaaa atcggaaacc
    14521 gttttactag atccgataac agctgtaaga tacggtgttc cgaaccaacc aattggtaac
    14581 cattcatccg attatatcga attgtcagac tataatttct gatgaacggt tccgttcgtt
    14641 tgatatcttc cataacagtc gtcttactaa catcaaccgc atctaccaaa tgatccagac
    14701 tgatgtaatc gatattagcg atcagagtca tcactatcaa tgcttgtctt tcactatcag
    14761 tgagaacgac aagttcctga tcatcaccta tgtcgtaatc aggctgtgat atcatttgga
    14821 taacctcgat tggtaccgta atatttccag aatgacttct ctgaattaac ggaatgttct
    14881 ttgttttcaa ttcttcatta aattgattga tcgcgtaatt gatttgacga cgtgtcaaat
    14941 caagttcact tgttaaagtg gaaagtttca tttcagggtt tttaataatc agtttgagta
    15001 tttcacgaat tcgtttattc attttgacta tcctcctgac aaaatcatta tatacttgtt
    15061 cacatacgtt tccggaaagc tttcatcacg ttttttgtca cacttggttt aatgttttgt
    15121 cacactaaca gctattttta aaatgaacgc tgttatatca aatgtaacat ggtatgacaa
    15181 ttattttagg gctaatgtga atattaaata ttcggtagaa tattggatgc tttagtaaat
    15241 aaacacggga cgttgcttct tcaacacatt aaagtatcta ttccgtaact aaatcaagtc
    15301 agtctaattg aaaaagaata atattaaact gctaaaaaca atgcttttgg gagcgtcaat
    15361 aattttgtgt aaatggttct tccctactgt agattgtttc taattctcca tcggttgact
    15421 cagcatttgt tcgagctcgc cttcggcctg ttggaaacct ttatgactgc gacctaggaa
    15481 tttttggttg taagtatcaa aagacgagac taagaaacgt tccatcgact cttcattttg
    15541 gaactgttcc ttgcggtggc tgtatttctt gatttgctta ttaaaggatt caatcaagtt
    15601 cgtagagtaa atagtcttgc gtatggctaa tgggaaatca tagaaagtga gcaggtaatc
    15661 gttcgaaagg atcgattcca ccatttttgg ataactggtt ttccattttt ccgcaaaagc
    15721 accacgtgct tccaatgccg cctttttaga tgacgcttga tacaccattt taaaatcatc
    15781 acagacttcc ttacgatcat cgacacgcac tttgtgactg atattacggg aaacgtgcac
    15841 acagcaatgt tgaaaacggg ctttggggta gaaccgctgc acggcccctg ccatcccctt
    15901 taagccatcc gtgatgaaaa ggaggacgtt tttcacgcca cgttcctgga ggtctattaa
    15961 aatctcttcc caaatcgtga tagattcagt tggtgcaatc gcatagctca acacttcctt
    16021 tgaaccgtcc gggcgaatgc caactacgat atgaatggct tccttggcga gggttttccg
    16081 ctttaaaggg atataggttg cgtccatata aatagcggca taacggtcat gaagctcacg
    16141 ttccttaaat gaagtgactt cttccgtaaa tgatttagtc atattggaca tggtttgggg
    16201 cgtgtagtga tgcccataca ttttctcaat caagt
//
LOCUS       DAKCAA010000055        15808 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000055 DAKCAA010000000
VERSION     DAKCAA010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.055"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            3..1868
                     /locus_tag="OUE31_002037"
     CDS             3..1868
                     /locus_tag="OUE31_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCU0223024.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            1882..3324
                     /locus_tag="OUE31_002038"
     CDS             1882..3324
                     /locus_tag="OUE31_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCU0223025.1"
                     /translation="MQSRFSEKFLWGGATAANQLEGAYDRDGKGLSVADAMPGGKQRF
                     AIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPN
                     GDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYE
                     RFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVA
                     SSKAVKIGHELRSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGE
                     YPAYTARTHKKYGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSE
                     GNLLGGVKNPFLEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDG
                     TIIDDYRIDYLRRHIEAMANAVADGVDLMGYTPWGCMDLVSASTGEMSKRYGFIYVDL
                     DDEGNGTLNRSKKKSFDWYKEVIASNGVNL"
     gene            3432..4133
                     /locus_tag="OUE31_002039"
     CDS             3432..4133
                     /locus_tag="OUE31_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCU0223026.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQEILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            4305..4784
                     /locus_tag="OUE31_002040"
                     /pseudo
     CDS             4305..4784
                     /locus_tag="OUE31_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            4822..5301
                     /locus_tag="OUE31_002041"
     CDS             4822..5301
                     /locus_tag="OUE31_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lyxose/D-mannose family sugar isomerase"
                     /protein_id="HCU0223027.1"
                     /translation="MFLDSGVVLKETELERIEYTDFGLGAIETEGLNLFVYENNERYC
                     GKELVLLPYQTCPEHRHPPRDENEGKKETFRCRKGLVYLYVEGKETKKLSCIIPKGQE
                     RYYTAKKEIILHAGDQYTIEQNIKHWFQAGATGAVITEFSSSSDDPSDSFTNPAIYR"
     gene            5712..6287
                     /locus_tag="OUE31_002042"
     CDS             5712..6287
                     /locus_tag="OUE31_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HCU0223028.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            6287..6727
                     /locus_tag="OUE31_002043"
     CDS             6287..6727
                     /locus_tag="OUE31_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HCU0223029.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVLAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFEKLPVETYVGEYL"
     gene            6743..7444
                     /locus_tag="OUE31_002044"
     CDS             6743..7444
                     /locus_tag="OUE31_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCU0223030.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDTFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(7942..8367)
                     /locus_tag="OUE31_002045"
     CDS             complement(7942..8367)
                     /locus_tag="OUE31_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223031.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGADSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATVTFTKIGNYRLKDKDGNIYSL"
     gene            8598..9923
                     /locus_tag="OUE31_002046"
     CDS             8598..9923
                     /locus_tag="OUE31_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCU0223032.1"
                     /translation="MKVVDRLSEKMLPIVSKMSSQRHLLAIRDSFIVTMPLVMAASVM
                     VLLNALIFSNATVQRILDLSPLAELASIVNNGTMSILAIIVCYNIGWNLATHYIQTGV
                     IDDPSFSPVHAGILSTAVMFILMSLSSTVTLMDGNTAEATGVFLQSLTSSSGLATAMI
                     AALVSTELFIKLAKMKSFKIRMPEGVPPAVAASFNSLVPEIVVILFFSVVVFTLNHTT
                     GLNVPQLIELAIQTPLKAFVLSVPGILFLQFFSDFLWVFGMHGSSILAPIRQAPLLQS
                     IQENMDAFSVGKEIPNIITEPFTNAFGLIGGGGCILPLVIAILWASKRQEQRSIAKFG
                     LTTCLFNITEPIMFGLPVVMNPIYMIPCAIIPSINLVIAYAATSLGIISKTVAAAPWI
                     TPPVIQSFIATGGDIRAAVLTVILIILDVFLFLPFVLAANKAKLAEGGY"
     gene            9925..12225
                     /locus_tag="OUE31_002047"
     CDS             9925..12225
                     /locus_tag="OUE31_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
                     /protein_id="HCU0223033.1"
                     /translation="MYDYPYQNPKLTIRQRVEDLLSRMNIAEKVGQVNQHLYGWECYE
                     KNGDKIELTEKLKEHVKWGGGLGALYGLFRSDPWSKTDYKNGIPAKESWKVANLVQEY
                     VLQHSRWKIPVLLVEECPHGHQGLDGISYPTNIGRGNTFNVALLEQSSRLMAKELAAK
                     GVHLALVSTLDLAKDPRWGRTEECFGEDPILSARFSEAVVRGFQGEIISEKVSFLDQT
                     VEEINKKKDQIGVVLKHCIAQGEALGGHNSGTVTIGRREFSDIYGPLLKSTRNAVGVM
                     AAYNDIDGIPCHINRALFEQTLRKEIGYQGIVMADGVALDRLSDVFTDKKTAAAYALA
                     AGIDLSLWDETYTKIAEAIDNQVVDEKLLDQAVRRVLSVKFLLGLFEQPFANDPKEYW
                     DHLMEESEHLNLETAKESITLLKNDGILPLDQQVKNIAVIGPNAHDVYHLLGDYSAPQ
                     TEDRLKKKIVQEIKTEFPQSKVSYAQGCEVRNQEDQEEKLLEAVTLAQNSDVIIAVLG
                     GSSARNFDMEFLRNGAVSSKGINMDSGENVDVASLSLGGYQEQLIEQLYQLGKPIITI
                     LVQGRPYDLMKIESFTNAIATAWFPGQEGGKAIAQMISGRNNPSGRLSLSYPRNSRQL
                     PVYYYQRAASKQENYYDLSGSPFYPFGHGLSYTTFEYSQMEVKTDIDKVIISIKVKNT
                     GSVSGKTSTLVYVRLIDGVVIQRTKLLKAFRKDELRSQEERLLVFELTSEDFSYMDID
                     DKRHYAKKAVIMVEQQEKEIKCNWQE"
     gene            12232..13203
                     /locus_tag="OUE31_002048"
     CDS             12232..13203
                     /locus_tag="OUE31_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0223034.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMEKISEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISNRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHAIDGLIVFLSEEEWSGFEMLTKMSIPVVALNCPGGPAGIDTIVVNDR
                     ESVAKVIAHHGGQGHKTIGFIAAAQTDYVARERLAGAKEAVQKDPSIHLEIFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            13225..14622
                     /locus_tag="OUE31_002049"
     CDS             13225..14622
                     /locus_tag="OUE31_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCU0223035.1"
                     /translation="MKRYQFPKNFWWGSAASGPQTEGRISGDGKGENIFDYWYKNEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HHYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFQLFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKAYHEMDQSGVI
                     GIILNLTPSYPRDESNPEDVKAARIADAFFNRSFLDPAVKGEFPSELIERIKELDLMP
                     EIHPDDLTIIKENTVDLLGINYYQPRRIKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEKGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDRNGFEA"
     gene            14778..15401
                     /locus_tag="OUE31_002050"
     CDS             14778..15401
                     /locus_tag="OUE31_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223036.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWEEYKLTANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLVVLLLTHDGDKVARLKNGKVVTAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     ASSQKNESTELSPSDSGSGQTITGNEENQASIITNESSEGQYQTYGQ"
BASE COUNT         5180 a         2628 c         3451 g         4549 t
ORIGIN      
        1 caatggataa tcaagcagtt ggtcgtcgtg tatgggaagc ggtaggagga caaaagaatg
       61 tcaaaagttt agtacattgt gctacgcggt tgcgattcag attaaaagat gaatctttag
      121 cagatacgca aaagttaaaa gaagacccgg acgtgatcca agtcgtacaa agtggcggtc
      181 agtatcaagt agtgattggc agtaatgtag cagatgttta tcaatcgatc gtggatgagg
      241 aaggtcttgc agtttcggag gatggaaaag aagagtccaa aaatattttg aatcgtctga
      301 tcgatattat ctctagtata tttacacctt ttctaggggc gatggcagcc gccggggtat
      361 tgaaaggatt cttatcattg gcaacggtga tgggctggct gacagctgat agcggtactt
      421 atcaaatatt gtttgctgca gcagatggtg tctttacctt cttacctgtc atgcttgctt
      481 ttacagcagc taaaaagttc aaagccaacc agtttttagc agtagcaatt gctatggcac
      541 ttgtgtatcc agctatcaca gcagttgctg gtgcgggaga agctatcagt ttctttggga
      601 tcccagtgat tctttcacca tctggttata cttcttctgt cataccaatc attctagccg
      661 tatgggttca aagtaaatta gagccattcg taaaaaaagt gattccgcaa tttctgcaaa
      721 tgattttagt tccgcttgtc gttttagtag tgatggttcc attaacattt cttgctttag
      781 gaccaatcgg gacggttgcc ggtaatgctt taggcggtct cttcaactcg atttatggat
      841 ttagtccaat cgtagcaggt ctaatcatgg gaagtttatg gcaagtattc gtgatgttcg
      901 gcatgcattg gggattcgta ccgatcatgt ttttgaatat cgaacaatat gggtttgatg
      961 tattgatgcc aatgcttctt ccagccatct tggcacaagg tggggctgct ttagctgtag
     1021 cattgcgaac aaaagatacg aaacttcgag cattagggat ttcttctaca gtgacttcgt
     1081 tatttggaat cactgaacca actgtgtatg gtgtgacatt acctttgaag aaaccattca
     1141 ttgccgcttg tatttctgga ggtattggtg gagctattat cggattttcc ggagtaaaag
     1201 ctttctccag cagtttggtc agcttattga cgattccgac tttcattaat acggtggatg
     1261 gtgtagagtc aaatgtgaca gtagcagtaa tagctacagg aattgctttt gttcttgcat
     1321 tcgtaggtac attgatttta ggatttgacg aacaaacaca agacaatcaa ttagaaaaca
     1381 aacatgcgaa tgcaggagaa ccgattactt cagcacggca taccttaaaa agtcctttaa
     1441 cgggtaaagt actgccattg agtgaagtac cagaccaagt tttttcttct ggcgtgatgg
     1501 gaaaaggtat cgctattgat ccagaagtag gagaactagt tgcacctgca gacggagaga
     1561 tcacgactat ttttccaact ggacatgctg tagggatcac aacgactgac ggagcggaga
     1621 ttttgattca tatcgggatg gatacagtag aattaaatgg gaatggcttt gagatcttag
     1681 tcaaacaagg ggatctcgtc aaagcaggag atttattgat tcgttttgac atcgaagcaa
     1741 ttagagcagc tggctatagc gtaatcactc cagttgtcat tacgaatact gatgcatttg
     1801 ccgatatact tgaattagac caaaaagaga ttattgcaaa cgaagatgtt ctggcaattg
     1861 taaaataagg aggaaatcag gatgcaatca cgtttttcag aaaaattttt atggggtgga
     1921 gcaactgctg ccaatcaatt agaaggggct tatgatcgag acggaaaagg gctatccgtt
     1981 gcagatgcta tgcctggagg taagcagcgc tttgcgatta tcggcagtga agaatttgac
     2041 tggacgattg atcaagaaaa atatatttac ccgaatcatc gaggaattga tcattacgat
     2101 cgtttcaaag aagatcttgc cttgtttgcg gaaatgggat tcaaatgtta tcgtttttcg
     2161 attgcctgga cacgaatttt tccaaatgga gacgaaggta ctcctaacga agcgggatta
     2221 gaattttatg atcagctgat tgatgagtgc ttaaaatatg atattgaacc tgtgatcacg
     2281 atttctcatt acgaaatgcc tcttcatttg gcaaaagaat acggtggctg gaaaaatcga
     2341 aaactgatcg acttctatga acgatttgct cagacagtat tagagagata cagcagtaaa
     2401 gtcaaatatt ggatgacttt caatgaaatc aattcggcct ttcactttcc agctttaagt
     2461 caaggattag taaaaagcaa tggagcagga gagtaccaaa atattttcca agcatggcat
     2521 aatcaattcg ttgcaagtag caaagccgta aaaatcggcc acgaattgcg ttcggatatc
     2581 caaatcggct gcatgattat ctatgcaaca acttacagca tcgatgccaa tccagtcaat
     2641 caggcagcaa caatgatcca aaaccaagaa ttcaattttt tctgcacgga tgtccaagta
     2701 cgtggagaat accctgcata cacagcgcgt acccataaaa aatatggagt cgatccggaa
     2761 aaattagagc aaacggaaaa agacttccag ttgctaaaag aatatccagt ggactacatc
     2821 ggatttagtt attatatgtc tacggcaatc aatgagactg atccacaagc agcaacttca
     2881 gaagggaact tgctgggagg agtaaaaaat ccgtttcttg aggcaagtga atggggctgg
     2941 cagatcgatc cagaagggct gagaatcgca ttgaatgaat tatacaatcg ttaccagaaa
     3001 ccattattca ttgttgaaaa cggtcttgga gccattgatc atatggaaga ggatggcacg
     3061 attattgatg attatcggat cgattattta cgtcgtcata tcgaagcgat ggctaatgca
     3121 gtagcagacg gtgtagattt gatgggctat acgccttggg gatgtatgga tcttgtcagt
     3181 gcatcaacag gagaaatgag taaacgttac ggctttatct atgtggatct agacgatgaa
     3241 ggaaatggga cactgaatcg atcaaagaaa aaatcttttg attggtataa agaagtaatt
     3301 gcctcaaatg gcgtaaactt gtaattaaag cagctgaatg aaaaagaaca cacttctcac
     3361 atgtgatttg tgttcttttt ttatttttta tgtgctattc ttttagtaat agtaaagcaa
     3421 agggtgacgt tatgaaaagg acacgtgtac tatacttgga agtcgcagat aaaattaaag
     3481 aagatatttt ctcaggaaaa tatccagtcg gttcgatgtt accgacagaa agtgaattag
     3541 aagaactgtt tcaagtcagc aaaatcactg tccgaaaggc aatcgaactg ctggcatcag
     3601 atgaatatgt cgcaaagaaa agtggtcgtg ggacgacggt tctaagcaat cgtccttaca
     3661 atcgattatc caaagcggca agctttacgc aaatcttgga gaactcccga tatgaagtcc
     3721 ggaaagaaac gctggatttg caattggtcc atataaagaa ggaagatcct ttgttttcct
     3781 ttttcggtga gcaagctgtt tgttttaagc gcttatatta tttgaacaat cagccttata
     3841 tttattttgt tcattatctt ccacaagaaa tgatgcaatt cagcagagaa gaatttggca
     3901 aagaatcttt gtatcgtttg ctgacgaaaa aaggatatac tattgactca ttttctgatg
     3961 atttctcggc agtattttta acagaagaag aacaagaaat tctgaaaaca gacgcacaga
     4021 tcggcatcaa acggatacgg aaatcgtcta cgcaaattgg ggaaatgatt gaatattcgg
     4081 aggcggtcta ccatacggag ctgcatcctt accatattga ttatgaaaca taaataaaaa
     4141 aagaggttgt gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagct
     4201 tctcatatta gcttctcata tttttcgttt ggttaggctt attaccgcag atacccggct
     4261 gtttctggat taccatttat tctggataag ggggtgtggc acgattttca gaaggaatct
     4321 atgaaccaat cactgtattg attttagctt cgatggtaac cccattcggc ttgacgatcg
     4381 cttatttctt agggaaaatc attcgtaaaa atatattcaa tcgtcaagaa atcgatacat
     4441 tgaagaccgc ttttcctatg gggatctgtc agatcacaga gggatgtttc cctatcgtat
     4501 tgaacgactt ggcacgcaat gtcatagcaa cgggagtcgg tggggcagtc ggcggtggat
     4561 tgagcatgtt ttggggcgca gatagccgta ttccggcatc gggaatgttt gcagtcgcta
     4621 cgatgaccag accatgggca ttcattggtg cattgttagc tggttctttt gctacgggaa
     4681 taactatttt attattgaaa aaaccagttg acccaaatgc agaagtcatc caagaagaaa
     4741 aagaggaaga agagatatct tgggatgact tgacaatcag ttaggaggaa cagaatggat
     4801 tacaagaaaa gagtacaaca aatgttccta gattcaggag tagtattgaa agaaacagaa
     4861 ttagaaagaa tcgaatatac agattttgga ttaggagcaa tcgagactga aggattgaat
     4921 ttatttgttt atgaaaataa tgagcgatac tgtgggaaag aactggtatt attgccttat
     4981 caaacttgtc cagagcatcg gcacccacct cgagatgaga atgaaggaaa aaaggaaacc
     5041 tttcgttgtc gaaaaggctt agtatatctt tatgtcgaag gaaaagaaac aaaaaaactt
     5101 tcctgtatta ttccaaaggg gcaagaacgt tactatacgg caaaaaaaga aatcatactt
     5161 cacgctggag atcagtacac gatcgaacaa aatattaaac actggttcca ggcaggtgca
     5221 acaggcgcgg ttatcaccga attttcttcc agcagtgatg atccaagtga tagttttacg
     5281 aatccagcta tttatcgtta atacaaaggt ttgggaacaa gctgatgaac caaaatgatc
     5341 aaatttcgat tatttggttc gtcggctttt ttatttagag aaacatcagg cgttggtgaa
     5401 acataacacg agaataaaat ggatttttca ttaataggag aaacaagtgt gtgactattt
     5461 aaataatgcg tgttattgac atgcaggacg aaatcccaat ttcttctata agtaagtcgt
     5521 ttcaatttta tatttactag ttatttattt ttttggttac tgtaaaatag ctgaaaaatt
     5581 atttttttgc aaatactata tatagtggtg tttgatctat ataccactaa aaaactacaa
     5641 aatctagtct tttattttaa aaaaacacgt gtagaatgaa gatagacttt tgagttaggg
     5701 agtgtttttt tatgaaactt actgtttttt gcggttcccg ttttggcaat aaagaaagtt
     5761 acaaatttat tgcgcaaacg ttaggaaaat atatggcaca agaagaaatc gaactggttt
     5821 acggtggttc atactccggg attatgggag tgattagtaa aacagtactg gaaaataacg
     5881 gaaaagtcac aggtatctat ccaaatggcc tttttgaaac tgagctgcct gggaaagatg
     5941 ttactacatt tattcctaca gagacaattg atgaaagaaa ggtattatta tttgaaaaag
     6001 gagatgctgt cctcgttttc cctggaggtc taggtacatt ggaggaattt tcgcaacttc
     6061 tttcttggat agcgatcggc ctgacacctg ataagccaat cggaatattg aatattggcg
     6121 gttattacag cggcttgcaa caattattag aaacttttgc aaaagaggat tttatggata
     6181 aaaaatggtt ggatcaagtg atcttttcca acaatccatt ggaactggtc aatgaattac
     6241 gagcagtatc tattaaaaat cagttattat tgaaggaggc aaaataatga gtcaaatata
     6301 tttagcagga ccattttttt cagaggagca aatcgatcga gtaagtcgta tcgaaaaagc
     6361 gttggaggaa aacaaaacag tcacaagttt ctactctcca cgtcatcacc aagaaagcaa
     6421 ttatgaacta ttcagcgctg gatgggcgca ggaagtatac gaaaaagata tggaagagtt
     6481 gacaaatgca gaatttgttt tggctatcct tgactttgag catcaaacaa tcgatccagg
     6541 aacggcttac gaattaggtg tggcaactat gttgaaaaaa ccgatgatca tcgtacaaga
     6601 agagacggta cctacgaact tgatgattac acaaagtctt cacacgtatt taaaatcaga
     6661 ccaagctgta cgtgaatatg attttgaaaa attgcctgtt gaaacttacg taggcgagta
     6721 cttatagaag aggaagggtt gtatgtcagt gattttgatt tcaggaacga ttggtgcagg
     6781 taagagcagt ttgacggata tgcttgcaaa agagattgat tctaaaccat tttatgaaaa
     6841 tgtcgaagat aacgaagtat tgccgctttt ttattcaaat cctgagcagt acgcattttt
     6901 attgcaaatc ttctttttga ataagcgatt tttagcaatg aaaaatgctt tagtgaacga
     6961 tgacaatgtg ctagaccgct ccatctacga agatagtctg ttgttccatc taaatgctga
     7021 tttaggtcgg gtaacggata tcgaagtaca gcagtacgat agcttattag atacgatgct
     7081 aaacgagtta gatgatgttg ctccaaaaaa acgtcctgat ttgatggtcc atatcaaagt
     7141 ttctttggac acgatgctag aacgtatcaa aaaacgcggg cgtgactatg aacagctaga
     7201 aagcgatgaa acgttataca cctattacga aacactgaac acccgctata atcaatggta
     7261 tgaggatttt gatgtatgtc ctaaaataca agtggatggg gatacattcg attttgtaga
     7321 aaatccagaa gatgcaaaaa aggtgattcg tcagatccaa gaaaaattag ctgaattgga
     7381 aggaaagcct gctggaaaat attttacaga taatcagcat gcgaaaggtc aagaattagg
     7441 ctaaaagtaa aaaaccaaac gacgggaaag aaaaattact acgtgatgta gaataagtct
     7501 ttctatcgtt tggttatttt atattcaaag atgtgaaata aataaaacgt tactctttga
     7561 tttgtgaact gaaatgatcc actgtttgtt ttactgattc cagtttttga agcttgatca
     7621 aaggaagaag ctgagtttga agttcataaa aatcagccat agtgagtttt gcttgatttt
     7681 gcttatcttc ttttgctttt tacataattt ttgacaggat aagattcaaa cgatttaaaa
     7741 gaatctttga ctagtttgtg gcaattgtcg catatactca aacttccttg atcattaaat
     7801 tctgtatgga tatttttgtt gttattacat gtacaataat caggactatc gatcatccat
     7861 ttcgtctcct ttacagtcat cttgcttctt tactatagca gaaaagaagg ggagaaacaa
     7921 aagaagatcc aacagatggc actatagact gtagatgttg ccatccttat ccttcaaacg
     7981 gtaattaccg attttggtaa atgtgactgt tgcttctttt ttattttctt ttcctgaaat
     8041 aatatattcg tcatctttgg tagtaatctt gatatctgtc agcactgttt tttcttcaga
     8101 tgattcagaa gaatcagctc cttgtgtctg atacgtgcgt gtccattcca tttttttatc
     8161 tgtaaatgtc aactgtcccg cggataaatc catatcttta cgtactttta gcgtatatac
     8221 actgttggtg atatctgctt tttccgcttt taagacagaa gaatcggttg tttcgtccga
     8281 ggattggtca gagccgccaa acaaatcaca gccagtcaat gtcaaaagtc ccgcagacaa
     8341 aataaatagt acgattaatt tcttcaaaat acttccccca tttgatagga taaagaaatt
     8401 ataccattgg aaagtaaaac ttcaaacgga tggaagagaa aaaattcaca aaataccatt
     8461 aaatagaata atttttcaaa agtcataaaa aatccaccac ctttagaaag cgttttaaaa
     8521 aaatgtgttg caatctttaa aaaaagtgct atattaaaaa tgaaccggtt caattttaga
     8581 atctaggaga tgaaataatg aaagtcgtag acagactatc tgaaaaaatg ctaccaatcg
     8641 tatctaagat gagtagccag cgacacttgc tggccattcg agacagtttt atcgttacta
     8701 tgccgttagt aatggctgct tctgtcatgg ttttgctgaa tgctctgatt ttttcaaatg
     8761 caacagtcca aagaatactt gatctaagtc cattggctga acttgcttca atcgtgaata
     8821 atggtacgat gagtatttta gctattatcg tgtgttacaa tatcggctgg aatttggcaa
     8881 cccactatat ccaaacaggc gtgattgatg atccatcatt tagtcctgtt catgcaggaa
     8941 ttctaagtac agccgtaatg tttattttga tgtctttatc aagtacagtc actttgatgg
     9001 acggaaatac agcagaagct acaggggttt tcttacaaag tctgacttct tcgtctggct
     9061 tagcaacggc gatgattgct gcccttgtca gtacagaatt atttatcaaa ttagcgaaaa
     9121 tgaagagttt taaaatcagg atgccagaag gagttccacc ggcagtagct gcgtcattta
     9181 attctttagt accagaaata gttgtcattt tatttttttc agttgtcgtt tttactttaa
     9241 accatacgac tggtttgaat gttccgcaat taattgaatt agcgattcag acaccattga
     9301 aagcttttgt tttatccgtc ccaggcatct tatttttaca gtttttctct gatttcttat
     9361 gggtgtttgg tatgcatggt tcgagtattt tggctcctat acggcaagca cctttgttac
     9421 agtctattca ggaaaacatg gatgcttttt cagtaggaaa agaaattcct aatattatta
     9481 cggagccctt taccaatgca tttggattga tcggaggtgg cgggtgtatt ttaccgttag
     9541 ttattgctat cttgtgggct tctaaacgtc aagaacagcg atcaatcgct aaatttggtc
     9601 tgactacttg tttatttaat attacggaac caattatgtt tggattacca gtagtcatga
     9661 atccaatata tatgattcca tgcgctatta taccatctat taacttggtt attgcctacg
     9721 cagccacaag tcttggaatc atcagtaaaa cagttgctgc tgcaccttgg atcactccac
     9781 cggttataca atcttttatt gctacaggag gcgatatacg agcagcagtc ttaacagtaa
     9841 tacttatcat tctagatgta tttttattcc tgccatttgt attagccgct aataaggcaa
     9901 aattggcaga aggaggatat taaggtgtac gattacccgt atcaaaaccc aaagttaacc
     9961 atccgccaaa gagtagaaga tttactttcg aggatgaata ttgctgaaaa agtaggacag
    10021 gtaaaccagc atttgtatgg ttgggaatgt tatgaaaaaa acggagacaa gatcgaatta
    10081 acagaaaagt taaaagaaca tgttaaatgg ggaggcggtc tgggtgcctt atacggtctg
    10141 tttcgctctg atccgtggtc taaaacagat tataagaatg ggattcctgc aaaagaaagc
    10201 tggaaggtgg ctaacctagt ccaagaatat gtactacagc attcgcgatg gaaaattcca
    10261 gttttgcttg tagaagaatg tccacatggt catcaaggct tggatgggat ttcttatcca
    10321 acgaatatcg gccgtggaaa tactttcaat gtagcattat tagaacaatc gagtcgattg
    10381 atggcaaaag aactggctgc taaaggtgtt catttagcgc tggtgtcgac tttggatctg
    10441 gcaaaagatc ctcgttgggg aaggacagaa gagtgctttg gggaagatcc gattctctca
    10501 gctcgttttt ctgaagcggt cgttcgaggg ttccaaggag agattatttc agaaaaagtt
    10561 tcttttcttg atcagacagt agaggaaatc aataagaaga aggatcagat cggtgttgtg
    10621 ttaaagcact gtatcgcaca aggagaagct ttaggcggtc ataattcagg cacagtaacg
    10681 attggacgca gagagttctc cgatatttac ggaccattat tgaagagtac aagaaatgca
    10741 gtaggtgtca tggctgctta taatgacatc gacgggatac cttgtcatat caatcgagcg
    10801 ctttttgagc aaacattaag aaaagagatc ggttatcaag gaatcgttat ggcagacggt
    10861 gtggctttgg atcgtttatc cgatgttttt acagataaaa agactgctgc agcatatgca
    10921 ttagcggcag gaatcgatct cagtttgtgg gatgagacct ataccaagat tgcagaagcc
    10981 attgataatc aagtcgtaga tgaaaagcta ctagatcaag cagttcgccg agttttatct
    11041 gtcaaatttt tattaggttt atttgaacag ccatttgcaa acgatccaaa ggagtattgg
    11101 gatcatctca tggaggaatc agagcactta aatttagaga cagcaaaaga aagtatcact
    11161 ttactaaaaa atgacggtat attgccgttg gatcaacaag taaaaaacat tgctgttata
    11221 ggtccaaatg ctcacgatgt ttaccacttg ttgggagact actctgcacc acaaacagaa
    11281 gaccgtttga aaaaaaagat agtacaagag ataaaaacag agtttcccca atcaaaggtt
    11341 tcttatgcac aaggatgtga agtaagaaat caggaggatc aggaagaaaa attattagaa
    11401 gcggtgaccc ttgctcaaaa ctcagatgtg atcattgcag ttctaggtgg atcaagtgcg
    11461 cggaactttg atatggaatt tcttcgtaac ggggcagttt catcgaaagg gatcaacatg
    11521 gattctggag aaaatgtaga tgttgcttct ctttctttag gtggatacca agaacagctg
    11581 attgaacaat tgtatcaact aggcaagcca atcatcacga tacttgtgca aggaagaccc
    11641 tacgatttga tgaaaatcga gtcatttacg aatgccattg caacagcatg gtttcctgga
    11701 caggagggtg gaaaagccat tgcgcagatg atttctggaa gaaataaccc aagcggacga
    11761 ttgagtttgt cttatcctag aaatagtcgg caactacctg tttattacta tcagcgtgct
    11821 gcttctaaac aagagaatta ttatgattta agcggaagtc cattttatcc ttttggacat
    11881 ggtctaagct atacaacatt tgaatacagt cagatggaag tcaaaacgga tattgacaaa
    11941 gtaataatat caattaaagt taaaaataca ggaagtgttt caggtaaaac aagtactctt
    12001 gtctatgtcc gattaattga cggcgttgtc atccaaagaa cgaaattatt gaaagctttt
    12061 cgtaaagatg aattgcggtc tcaagaggaa agactgcttg tttttgaact cacttctgaa
    12121 gactttagtt atatggatat tgatgacaag cggcattatg caaagaaagc ggtcatcatg
    12181 gtcgaacaac aagaaaaaga aatcaaatgt aactggcagg agtgaaaatg tatggcatcg
    12241 atccgtgacg tggctaagat ggctggtgtt tcagtgggaa cagtttcccg ctatttaaac
    12301 ggtcagcagc tgaaggaaaa gaatatggaa aaaatatcag aagcgatttc agcgttggac
    12361 tataaagaaa acatcattgc taaaggattg aagaataatc gaagtttctc tattggactg
    12421 ttgataaacg ggatatctaa ccgatttggt tcggaggttg tttcagggat cgaaagagta
    12481 gctgaagaaa atgggtatag cttattatta agcgggtttg ccgatcagcc agaaaaaatc
    12541 gaacaaaaaa tcgaatacct gatgaagcat gcgatcgatg gattgatcgt cttcttatca
    12601 gaagaagagt ggtctggatt tgaaatgctg acaaaaatga gtatcccagt tgtcgcattg
    12661 aattgtccgg gtgggccagc aggtattgat acaatagtag tgaatgatcg agaaagtgta
    12721 gcaaaagtga ttgctcatca tggcggacaa ggacataaaa caataggatt tattgctgcc
    12781 gctcaaacag attacgtagc aagagaacgt ttagctggag ccaaagaagc ggtacaaaag
    12841 gatccgtcta tccatttaga gatctttaca ggagactatt ctagaaaaag cggctattac
    12901 ggggcaaaag cattattaga aaaaggggca actgctattt ttgtcagcaa ttacaacatg
    12961 tcgattggtg ccatcgaatg tttcaatcaa gaaggtgtca gaatcgggaa ggatattgcg
    13021 ttcagtcact atgattattt agataaaaac gatctgagta tccttccaaa aatcacgatc
    13081 acgccaccaa cagataaaat cggggaacga gcagcagaac agctgttgaa acgaatcaaa
    13141 aaagaagagg aagaaaatga aaaagtgatt gtgatggaaa atatcataca tggaatcaac
    13201 taaaaaagaa aaagaggtgc tttgatgaaa agatatcaat ttccaaaaaa tttttggtgg
    13261 ggctctgcag caagtggtcc acaaacagaa ggaagaattt caggcgatgg aaaaggagag
    13321 aatatttttg attattggta caaaaacgaa ccgcaaaagt tctttgatca agtaggacct
    13381 gaaaaaacct cgcaagttta tacgaagtat caagaggatg tacagttgat gaaacagact
    13441 gggcataatt catttcgaac ctctatccaa tggagccgtt tgatacctga tgaatctgga
    13501 acaatcaacg aagaagccgt tcgtttctat catcactatt ttgatgagtt gattgaaaac
    13561 ggtatcgaac cctttgttaa tctgtatcat ttcgatatgc cgatgtatct gcaagaaaaa
    13621 ggcggatggt tgaaccgaga aacggttgaa gcctatgaaa aatacgcaaa aagttgtttt
    13681 caattgtttg gctcgaaagt aaaaaaatgg tttacccata atgaaccaat cgttccagtc
    13741 gaggcaggct atttgtatcg atggcattat ccggaagaat cagatatgaa aaaggcaatc
    13801 caagttggtt atcatgaagc gttggcttca gcattagcca tcaaagctta ccatgaaatg
    13861 gatcaaagcg gtgtgatcgg aatcatctta aatttgacac cgagttatcc aagagacgaa
    13921 tcaaatcccg aagatgttaa agcagcacga atagcagatg cgttcttcaa tcgttcattc
    13981 cttgatccag ctgtaaaagg cgagtttccc agtgaattga ttgagagaat aaaagaactc
    14041 gatctaatgc cggagattca tccagatgat ttgacgatca ttaaagaaaa cacagtagat
    14101 cttttgggaa ttaattatta ccaaccacgc cgaataaaag caaaagaaac accaatcgat
    14161 actaaaaacg gtcctatgcc tgaggattac ttcgacaatt atgaaatgcc tggtcgtaaa
    14221 atgaatcctt atcgcggatg ggagatctat gaaaaaggaa tctatgatat tttgatcaat
    14281 gtacgagatc attatgggaa tatcgactgt tttatttctg aaaacggcat gggtgtagaa
    14341 aatgaagcac gatttatcaa ggaagatggt atgatccacg atgattatcg gatcgaattt
    14401 gttcaatctc atctgaaata tgtccatcaa gccattcaag aaggtgccaa ttgtttaggt
    14461 tatcatatgt ggacatgcat ggataactgg tcgtggacca atgcctataa gaatcgttac
    14521 ggttttattt cagtagattt agcacaagat ggaaaaagaa cgatcaagaa atcgggtcat
    14581 tggttcaaag atgtatcaga cagaaatgga tttgaagctt aaagaatagc caagagagaa
    14641 tgtatgaaaa ttcccgttct taccgcttca ggaaaaagaa gttcaattat ttacgatctt
    14701 tttcaacttt tttgtctttc tatttcattt tttgtatata atagaatagt caaaattaaa
    14761 taggagtgga ggaaggcatg aggaaaaaaa gaccgtttct tctcttttgg ttattcggtt
    14821 ttttcttact gcttatttta tccgcagcat tttcaggaaa aatgacagca gatcttgctc
    14881 agaaagaaac agaaaaaatc gtagcaagca aagaatcagt agataatttc aaaaaagaat
    14941 tctcaactta ttggtgggag gaatataaat taactgccaa ttacgaaaaa ggtgaattgg
    15001 acatctattt gccaaaagga aaagaagaaa atcaatttat caatatcgat gacgtactta
    15061 gtgcgatttc tctcagacaa tatcaattca aagacaaaca tttggtcgtt ttgcttttga
    15121 ctcatgatgg cgacaaggta gcacgtttga aaaatggaaa agtggttaca gcttattctg
    15181 aaaaagtgga caaaaaagtg gtggccgatc gactagcgga atggaaaaag accaacgaac
    15241 aagtcaagaa aacaactgct tcttctcaaa aaaacgagtc gacagaacta agcccttcag
    15301 attctggcag tggacaaacg ataacgggaa atgaagaaaa tcaagcctca atcattacga
    15361 atgagtcatc agaaggacaa tatcaaacct atggacaatg aaaaacagaa gttgtgacag
    15421 aagtggtcag cttcaagaaa taagaagaaa tttacgaaaa gtgcttctca agtttttgta
    15481 aaatttcggc ttatttccga agaagctact tctggaacac cgtgaatcag aggttgtgaa
    15541 atcagcggtt tgacctgagt attagagaaa aaaacgggaa aatagctcct catattttgc
    15601 cgttttttga gctaataccg aaggtcagct gattgaacac cgtttagtgg agaggttgtg
    15661 aaaaagctgt cctgcatcaa gaaataggga gctgcgacaa gaattttgtc acagcctctt
    15721 tcctacgatt agtcaagtaa aaggtgcaag aaaaatagct cgtaaacgaa agcgacaaaa
    15781 tcaaggcaca ctaaataaag ccccgttc
//
LOCUS       DAKCAA010000056        15680 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000056 DAKCAA010000000
VERSION     DAKCAA010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.056"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..421)
                     /locus_tag="OUE31_002051"
     CDS             complement(<1..421)
                     /locus_tag="OUE31_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCU0223037.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKEN"
     gene            581..1087
                     /locus_tag="OUE31_002052"
     CDS             581..1087
                     /locus_tag="OUE31_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCU0223038.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            1255..3168
                     /locus_tag="OUE31_002053"
     CDS             1255..3168
                     /locus_tag="OUE31_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HCU0223039.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            3173..4174
                     /locus_tag="OUE31_002054"
     CDS             3173..4174
                     /locus_tag="OUE31_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCU0223040.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(4376..4582)
                     /locus_tag="OUE31_002055"
     CDS             complement(4376..4582)
                     /locus_tag="OUE31_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HCU0223041.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(5228..6076)
                     /locus_tag="OUE31_002056"
     CDS             complement(5228..6076)
                     /locus_tag="OUE31_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCU0223042.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            6075..7142
                     /gene="gnd"
                     /locus_tag="OUE31_002057"
     CDS             6075..7142
                     /gene="gnd"
                     /locus_tag="OUE31_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HCU0223043.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            7144..8145
                     /locus_tag="OUE31_002058"
     CDS             7144..8145
                     /locus_tag="OUE31_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HCU0223044.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            8142..8426
                     /locus_tag="OUE31_002059"
     CDS             8142..8426
                     /locus_tag="OUE31_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HCU0223045.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            8459..9256
                     /locus_tag="OUE31_002060"
     CDS             8459..9256
                     /locus_tag="OUE31_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCU0223046.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            9270..10103
                     /locus_tag="OUE31_002061"
     CDS             9270..10103
                     /locus_tag="OUE31_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCU0223047.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            10121..10978
                     /locus_tag="OUE31_002062"
     CDS             10121..10978
                     /locus_tag="OUE31_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCU0223048.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            11000..11509
                     /locus_tag="OUE31_002063"
     CDS             11000..11509
                     /locus_tag="OUE31_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0223049.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            11546..11947
                     /locus_tag="OUE31_002064"
     CDS             11546..11947
                     /locus_tag="OUE31_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223050.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            12059..12412
                     /locus_tag="OUE31_002065"
     CDS             12059..12412
                     /locus_tag="OUE31_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223051.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            12446..12889
                     /locus_tag="OUE31_002066"
     CDS             12446..12889
                     /locus_tag="OUE31_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCU0223052.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            12906..13991
                     /gene="uxuA"
                     /locus_tag="OUE31_002067"
     CDS             12906..13991
                     /gene="uxuA"
                     /locus_tag="OUE31_002067"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCU0223053.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            13984..14697
                     /locus_tag="OUE31_002068"
     CDS             13984..14697
                     /locus_tag="OUE31_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCU0223054.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(14904..15053)
                     /locus_tag="OUE31_002069"
     CDS             complement(14904..15053)
                     /locus_tag="OUE31_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223055.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            15449..15649
                     /locus_tag="OUE31_002070"
     CDS             15449..15649
                     /locus_tag="OUE31_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCU0223056.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         5420 a         2456 c         3313 g         4491 t
ORIGIN      
        1 tattttcttt aaaatcgaca agatgaccag aaagcaagag ttcgttgagc tcttgctttc
       61 ttttagtttt agaaaggaac atcctgattt tatcttcgct aaatccagtc aaaagttttg
      121 cagattggtc gtagataatc ggttttttca ataaagaagg ggatgtacga atctcaatat
      181 atagttcact caaactgagt tcatctattc tgtgaacaag atttttataa ctaatagaat
      241 gagtagagag catttcggtc acgccgttgt ttgtcaattt tagtaagtgg ataaattcat
      301 ttttggttag tggttgacga attaagttct gttcgataaa cggtatatca tggacgataa
      361 gccaacgttt tgcgcgtctt gaagacgagc agccagaacc tgtatacaat ttaatcatca
      421 tacattcctc caatagctaa gtatttatga aataataaca tgaagaaata gtcgaaaagt
      481 gccatttaga ggtgtaaaat aagaaaatgt tgtcacgtat aatggaacta gctagataag
      541 aaatactatt aaatcaagaa aaaagaaaga aggcacaagt atgtcaaaca cagccgacgc
      601 aatagtagtg atcgatttac aaaaaggggt atgttttgat tcttcgccga tacacgaatt
      661 agaaacagtg acagcattag tgaataaaag aatcaaaaca tacgaaacga ttgggaaacc
      721 agttattttc gttcaacacg aagatgctca attagtgcca caaacaaaac catgggagct
      781 attgtcggaa ttatctattc ctgagcacag ttattttgtg agaaaaaccc atgcgaattc
      841 attttataag actaatttga gtgttttatt aactgaattg gactgtcatt cgatcgaatt
      901 atgtggggca caagcagagt attgtataga tacgactgtg aagtttgctc atggattagg
      961 ataccagctt atgatgtgta gaggagcaac gacaacttat gataatcctt ttatgaaagc
     1021 aaaggaaaca atcgcttttt acgagaaaat ttgggataaa cgatttctga catttttgga
     1081 gcaataagtt gtttcttcgt ttaaaaaaag cagaatggat actggtttat ccattctgct
     1141 ttattacgta aaatgagaaa ataatcctgt tctattttta tgggataaac catttatttt
     1201 ttgtataaaa aatgtttgcg tttacatata attctcctag aaacataaaa aggagtgaat
     1261 agcttgagaa caaaacaagt attaaaggga gcgttggtca tcttatttgc tgtaagtaca
     1321 agcgtcccgc aatggacagt atatggagag agcatttctt ccgaatcgga atctcgggag
     1381 gtagaaacca cagaaactac tgatgctgga aatgaaacga aatcgagtac ttcacaaaca
     1441 gaaacaaata ctgaaacaac ggttgagaca tctgttacta gcacagatca agaaacgacc
     1501 gctaccacag ataaccaaca aacagaagaa gcaacagcta caaaaatgtc aaacgacgaa
     1561 tcctcttctg ctaaagtaag tgacaaagag aatgggacag aaaatgatga tatcggtaaa
     1621 ggtgaaaatt tcaatggtaa agaatatttg aattacttcg gtaaacagat gacagaaata
     1681 cttaatggac caacagaaga catcaagtca aaattaatag agttattagt cactgagctt
     1741 gctgttaatg attatggtgt agataaagag attatcaaac atctgattgc tacttatcta
     1801 ttgtacgata tcgcttttgc aaaaaacagt gtgttgatgt cgatgcttgg aggtacagat
     1861 gatgggacaa cgcctacaga aaacacaggc ttctatccaa atacaaaaca acttcatcaa
     1921 actgtactaa acaaacaaga tggcaaaatg atggatgtat atgcatatta tgtcgatcaa
     1981 ggttcagata aaacagtcat gatccatggc ggatttcgag ggaattggaa taacgggatc
     2041 gttacagaag aatacaatga tttttataag gccgggtata atttattatt tgttgattcc
     2101 agagcgactg gtaatagcgg aggcgattat gtgacctatg gacaatatga gtcagatgac
     2161 gtcctttact ggataaatca agaagttcga gagcggccat ctcaaaagat tttactttat
     2221 ggtggttcga tgggagcagc tacgatgatg tctgtattag cgaaagatat tcctgtcaat
     2281 gtcaaaggaa ttattgaaaa ttgcggattt gcatcaattg atgaacaact acgttttacg
     2341 tacagccaga cagtagcccc cgcactaccg gatgccataa aaaatcagtt agacatcatt
     2401 ggggatcaag agcatgaaga tttatttatg ggccttttga aacaatacta ttttgatcag
     2461 gagatgcatt tggatacaaa agctgctcta cctacgattg gaatgtcaga ttcattgcct
     2521 aaattgatta tccatggaac agcagatgat gtagtacctg tgtctaacgc gcaaaaatta
     2581 tatgagttat caggagggta taaagatctt ttattagtag aaggagcagg gcatggaaag
     2641 gcacaggaag ttgaccatgc tgcctacacg aaacatgtaa cggacttttt gaaagtagtg
     2701 ttccatgatc agataaacgt aaagtatgtg gatgaaaaca ataaaagtct actcaaagac
     2761 caggacgaaa tccagcttta cggagcttat ggagaaaatt atatgacaga gcaaaagaca
     2821 ttcgaaggat acgaattagc aaatgttgaa ggaccgactg aagggatttt taatgagacg
     2881 ataccaacta ttattttcta ttacaaaaaa atcccagtag ctccaccaaa aaagcaagat
     2941 ccgacagaga atgcagacaa taagggaaag aatgaacctc gagaggatca atcaagtgat
     3001 gatacgcaac cgattcagat gacagtgaaa gtacaaaaaa agacagatgc aaaaaaaaga
     3061 atgttgccga aaactggaga aaagaaacat tcgcttctca tttattcagg tggattttta
     3121 tctgttagca cgattatcac atggatttgg cgaagaaaga gagggtaaat gaatgaaatg
     3181 gttcaagcga atagtgattg cagtaccagt tatcatcgta gttattttag tcactgtatt
     3241 tttgattaat caaatcacac caaagccgat tagcttgctt gttagaaaac aatttgacac
     3301 aagtgaaaaa gaacaagtat atgcccgacc agatgatttc cagcaaaaaa tcgaacaaat
     3361 cgatataaaa aaagaaatat cctatccttc aaagtacaaa aataataata tggatatcta
     3421 cacaccgaaa gtggaaaaga aaaaattacc gattcttttc tggatgcatg gaggcgcata
     3481 tgtaggaggg gataaaaatg attgtcgtga ttatttggaa tatctatgtt cagacacgca
     3541 gcaaatcatc gtaaatatag attatgaacg atcaccggaa gcaaaacatc ctacaccagt
     3601 tatccaattg aacgaagcca ttcaagcagc taaaaaagag ataaaagatc aagcagattg
     3661 gtcgaatatt tcgattggtg gaaattcggc aggtgcacaa attagtggag aatatttgtt
     3721 agcacttcaa aatgaagaaa ttaaaaaagc tgatcatctt gatccgactt tggagaacaa
     3781 gcagattacg aagtttattt ctttgtctgg tctgttggat ccttctgcac ttactcaagt
     3841 aagtgataaa atctctagct ttctttatga aaaatgtgga tgggcttact ttgataataa
     3901 ggactttgaa caatcagaga aggtcaaaag tttagccttg gtcagacatg cggatcgttg
     3961 gacgcaaaac acattcttaa cggatggaaa tacaaatacg tttacgaaac aaatggaaga
     4021 agtaacttct gtatttgaga aagcgggggt gaaagtcaca aaagtagatt atgcggagaa
     4081 aaatgctgtt ttgaaccatg aatatcagtt tgatttcagc aataaacaag cgcaagaaac
     4141 atatcaaaag ttagtaatgt ttttcaagga gtaaagtctt atgatgcaaa agaggttgta
     4201 atctgtcact tagctccaag tcacaaggag caatttcaat aaacaagctt ttcatggttt
     4261 atgaatattg taacttgtga ctgaggagtt agagatggca aggggcacct tttattcgaa
     4321 atttgggaat atcacacgat tattgtcacg atctctttta cgtaaatttt ataagtcaga
     4381 tttgttgttt tgatcgttta aaaaaagcaa caaatccgaa gcctgcggag gcaagaaggg
     4441 acaaaaagcc gagtggtaag caaaagaatg ctggttccac taatattccg ttgttattga
     4501 tataaggctg ggaacaaaga tgaatagcaa ataaaatcaa tgcactagcg aaaaaaagca
     4561 aagaaatatg gatagctttc ataagcagca cctccttttt tataattgta tgataaatag
     4621 attaagaatc tataaatgtg acaagtttgt taggatgtga ataaaatgat catctagcga
     4681 acttgaaaca aagatggcta atgataagca attaatgatt cagcaatcag ataggtacaa
     4741 agtttaccat catacgtcta gaccaataat agaaaatatg ggaatataat agaaaagatt
     4801 taggataccc ccaaaagaat ttccccaaaa attcgatgta tcctaaactt ttttatttta
     4861 cataacaatc atatcaactg tgaaataaaa ttacaaatga taacctaaaa tgaggccaaa
     4921 agccagtgtt atcaaggaaa tacttaattc accaaaattt tttttaattt tttagaaaat
     4981 aagaaacaaa aataataaaa aaaagaaaag ataaattttt tactactgta tactaacttt
     5041 gttatcgcat ctaacaagta actcgaataa taccaataca accttctcca aagatgcgat
     5101 gacatacgtt ctaacccacc gactattgat gttctgtacc acccttgcag aaccaaaaaa
     5161 gccactacca aatatttggt agtggctttt tttgttttat ggatttttcg ctttttctgt
     5221 tatggtgcta ttctttgatt tcagaaatag tatgtcgaac tttagcgata gaacgacgtg
     5281 attctttttc gttgtaaaac atcaaaatca catatagaga gtccaaaatg cttagttgag
     5341 aaatacggga agctaaagct tcagatcgga attctgtttc ttcagaaata gaaataaaaa
     5401 cgacatcgcc aagtttagca agggaagaat tagcttggct agtaataacg attgtttttg
     5461 ctccagtttt tcttacggtt tcagcaatat ggattgtttc ttttgattgc cctgtgtgag
     5521 aaatcaaaac agcacagtct ttttccgtca ataaagaagc ttccatcaat tgaatatggt
     5581 aatccgtgct gtgagaagtt gcgatagggg aacgcaaaaa tttatgataa gcgtcagttg
     5641 ctacaatctc tgaaccgcca acaccgaaaa aatagacacg tttagattca ttgataatag
     5701 tagccgcttt ttttagatcc ttttgttgta acaacttttt tgtgtcattt aaagttgaaa
     5761 tactagactc gaacaccttt tgcgccatag tgagctcagt atctgttttc tgaatatttt
     5821 cgtggataga aatagcagat agatcatttt cttggatcaa catggccatt ttaaaatctt
     5881 taaatccatt ataaccaagt ttttttgtaa attgaaaaaa agtagagtca gcaatgccca
     5941 gttcacttgc taaattgcta ataggactat gacttacttt gcttggattt tctaaaatat
     6001 aatcggcgat agcctgttct tttgggctga agtcgttgta cattgttttg atttgtagtc
     6061 ttatggagac gctcatgaga attcctcatt ttcataataa gattatcatt ttttccgttc
     6121 tcattaatgt taaagataca aggagagtag gaaaaaatca aacaaaaaat atttttgtaa
     6181 aatctattta caaaaaaatt tttttgtata atgagggtat aagaaatgga ggcgctatca
     6241 tggaaattgg tgtaattggt ttgggaaaaa tgggattgaa tttagcttta aacttaaaag
     6301 agcaccatca caaagtacaa ggactcgaca tttcaagtac agctgttagt caggcaagag
     6361 aaaatgacat tcctgcttat caagagatct ctgaatttct agctactttt gagcagaaaa
     6421 aaatcatctg gttaatgctt cctgctggag agataaccga aaacatgtta agaaaacttt
     6481 ttccaaaact cggaccagga gacattatta ttgaaggcgg aaactcttat tataaagatt
     6541 caatccgtcg agcagaagag tttcagaaaa atgaaatcgg ttacttggat tgtgggactt
     6601 ctggaggaat cgaaggagca cgacatcaag cctgcttaat gattggagga gataaagaaa
     6661 cttttctatc cgtggaacaa ttattcaaag atgtagcaat tgaaagagga tatctgtatg
     6721 ctggtgcatc cggaagcgga cacttcttga aaatgatcca taatggaatc gaatatggaa
     6781 tgatgcaagc aatcggtgaa ggattccaac ttgtacaaaa aagtgagtat gcttttgact
     6841 tggaacaagt cgcacgtgtt tggaatcatg gttcggtgat tcgcggctgg ctgatggaaa
     6901 tcatggaaga tcagttaaac gaacatccca atttaagtaa ttatcgggga atcgtttctg
     6961 catcaggtga agcaaaatgg acggttgaaa cagcgctaga aatggctgtt ccagttccag
     7021 taattgcaac tagtttgttc atgaggaatc tttcacagga agaagatagt ttttcagcaa
     7081 aagtagtttc agcactaaga aatgggtttg gcggacatga aatagttgaa aagggtgagt
     7141 aaaatgccag attatcatat agcaatcgtt aattccagca gtttcggaag agtctttcca
     7201 caccacttgg aaagattaaa gtcagttgga gacgttcatt tctttactgt tgatcaagag
     7261 attccaggaa aagaactagc ggagttactt aaaggattca atatcattat tgcaagtgtt
     7321 acgccatttt ttcgacgaga tttttttgaa aacaaagatg aactgctatt gatttcccga
     7381 catggtattg gttacaacaa tattgattta aaagcagcaa aagaacacca gacaatcgta
     7441 tctatcatac ctgctttagt tgaacgaaat gctgtagcag aaaataatat aactaatttg
     7501 ttgtccatgc ttcgacgcac gacacaagca caagcaagag tcaaggacga tcgatgggaa
     7561 gatcgggcgg agttcgtcgg taggacgctg tttaacaaaa cagttggtgt gattggtgca
     7621 ggaaataccg gaagcggagt aatcgaaatt ttgcgtaacg gttttcgctg tgatgttcta
     7681 gcttatgatc cttacaaatc agatttatac atcgaaagct ttggtgcaaa aaaagtagaa
     7741 cttcaagaat tactggaaca atcagatatc atttgtttat gtgcgaattt gacagaagag
     7801 aactatcaca tgatttctga taaagaagtc gatcagatga aagaaaatgt ttatctatct
     7861 aatagtgcaa gaggcgctct agttgatgaa gaagcgatga ttaatggtct gaaaagcgga
     7921 aagatcgcag gatatgccac agatgtttta gaagaagaac cgggacgtca agatcatccg
     7981 tatttagcgt ttgaacaagt agtgattacg ccacatatat cggcctacac aagggaatgt
     8041 ttagaagcaa tgggtgaaaa atgtgtcaga gatgtcgaac agatcagtca gcaccttctt
     8101 cctgaacgtt ctgtccagac aaagagcaac tatataaaag gatgatgaag aaaatggtga
     8161 acggtttaaa agtgaaaaca ggccctcaat tttatttata tgaagaaggt ggtatttcaa
     8221 aagtttctga tctcttgaaa tcatacggcg cgaaaagagt actggtcacc cacggaacgg
     8281 tatcatggga aaaggcgcta cctaaattag tatttttgaa tgacgaaacg attcaatttt
     8341 tttatcatcg ttattctgga gaatgtagtt atgctgaagc cagacgaata gctacaatca
     8401 tcaaaaaaat gaaatcgatt tcgtagttgg cgttggcgga ggaaaactga ccgatctagt
     8461 gggttatagt gccaatcttg caagaatcga tttcggagtc atccctactt tagctagtaa
     8521 ttgtgctcca tggacacctc ttgctgtcat gtataaggag aatggacaag cagaagggaa
     8581 aacagaacac ttttacagac aagctgcttt ttttataaca gatccccaat tagtgattga
     8641 ttcccctgtt ccatatttca ttgccgggtt agcagataca ctagcaaaat ggtatgaatc
     8701 tgagctcatc ttagaacaag attttttgca agatgaatca tttttgaagc tagcacaaga
     8761 tactgcgaag atctgcaaag aagagatttt gaatcattct gctaaagcaa tccaagatat
     8821 ggcacaaaga aaactgacat cggagttcaa acagctttca gagattatct ttgctgttgc
     8881 tggtttagtt ggaggattag gagataaata cgcaagaaat gcggcagcac atgctatgca
     8941 tgacgctatc agtaaatata ttccggaaag ccatcgtttt ctacatggag aaaaagtagc
     9001 gtatgggatt ttctatcaac tggcactaga aggtcgctgg gaaaaaatag acgagttata
     9061 tcctttgtat cgggaattag aactgccggt ttctctagaa caaatgggat tatttccgaa
     9121 agataaacag ataatagata aaatggctga atttattgat tcgaaagaga aagtgcattt
     9181 gattcctata gaggtaacac agaaatcact gatacagtca atgatggaac tggaaggtta
     9241 tatcagaaag atctgaagga ggaggacaca tggaaacatt aagtgtagta caaagtttgt
     9301 tgattgcttt atgggtagcc gcggttatgt cccgctggtt aggtggagga gccacgttga
     9361 ccttacgttt ttctcctttg atgactggat tagtcgtcgg gttgatcatg ggggaagttg
     9421 cacaagcgat gattgttaca gccgctttgc aaatgattta tatgggggtt ttttctccag
     9481 gaggatcaat gccagctgaa ccatctattg cagcagctat cgcagtacca gtcgcattat
     9541 taggggatct gtcgccagaa gcagcgattg ccgttgcggt gccagtcgga ttgctcggaa
     9601 gttacttgta tcagtttcgt tttttcatca atactttttt aggtaaatat acagacaaag
     9661 ctgtagaaga tttgaataca aaagctatgg cccgatcaat tattctttat ccaacggttg
     9721 cctcattttt attattcgtt ccgcttgttt tcattgcttt atatttaggg gcgccattga
     9781 tcgctgatgt aatcaaagct ttagagggaa cagtcgttat ccacattctt gaagtagtag
     9841 gtggagggtt agcggcaatc ggtatcgcga caactgtata cgttatcggt cgaaaagatt
     9901 atctggtctt tttcttcctt gcttatttta tgagtgttgt tttgaaatct ttagatatta
     9961 cgatggttac ttatgccatt tttgggatta ttatcgcttt gatctttgtc cagtcgcaaa
    10021 aagggaaaca agtacagcct gccacaagca ataacaattc agcatctttt gatgacgaag
    10081 atgactatga tgacggattt taatttagga ggaatgggaa atggctgaaa taatggataa
    10141 tcaaacaggt gctcctgaag aaatcacgaa aaaagatgta acaaaagcct atctgagatg
    10201 gcattttgca aacgaaattc ctcactcttt tgaacgttac ttggcgccat cactactata
    10261 cggaatgatg ccaatcttga aaaaacttta taaagatgaa gactctttaa aagcagcata
    10321 taaacggcag ttactgttct tcaacactca attaagctgg ggtggcggtg tgattactgg
    10381 cctaatgtct tctatggaac agcaaagagc agaagaagag tatgaagaaa aagagatctt
    10441 gatgcaggat gacttgatgt ataacacgaa agcgggattg atgggggcac tagcaggaat
    10501 cggagatgca atcgattcag gaaccgtcca atatattttt atcgcaatcg cggtaccttg
    10561 ggcacaacag ggaagtcctt taggcgcact ttttcctttt atctgctttg ggttgtatca
    10621 ggttttacta ggggtatttt tcgcaagaca agctttcact atgggccgta atgctacagg
    10681 cctaatgcaa aacactggtg ttcagacagc gattgaaatg ctatcagttt tagggttgtt
    10741 tatgatgggg gtgcttgcgg gaaactatgt aaaagtagaa tcttcattga aatttgcgat
    10801 atccggacgt gagtttgtta tccaggaaat tcttgatcaa atcgtgccag ggatattacc
    10861 tttagctgtc gtaatgggtg tgtacttgtt ctatacgaaa aaaggattga aagtcacaca
    10921 agcattatta tggctgactg gaatattaat tgtgctagca ggaatcggta ttttataaaa
    10981 agaagggaac gtgaataaga tgggtgtagt caatttagcg cgtgtggatg agcgtttgat
    11041 ccatgggcaa gtaatggtaa cgttatctca aaaaagtgga gtgaattcca tttttgttgt
    11101 agacgaagtt gtagcaaaag ataaatttat gagagatctt tacaaaaatg caggaagccg
    11161 tacaggacaa aaaacaattg tcattacacc agagaaagct aaattctatt gggatgaata
    11221 tcaatttaaa gaatacaatt gtattttgat cgcaaaaaca gtccaaacga tttacgactt
    11281 agtaaaacac ggaatcccca tggaagaatt gaatattgga gggattgctc aaaaaaatcc
    11341 tgatacagat cttttagtga cgaaatctgt ttatttaaat aaatcagatg ctgaaaaatt
    11401 gaaagaaatg aatgaacaat atggcgtaaa gaatatttat tttcaagcca ctccatctgc
    11461 acctaaaaca ggattaaaag atgtattgaa caagtttgat ttgtcataaa caaatgctta
    11521 gaaaaaagat aaagagggcg aaaaaatgaa gaagaacgag ctgtttcgtg attgggaatt
    11581 tcgttatcgc tatatttacc gtaagcgccg tacaaaaaag agtaaacagc gttttctttc
    11641 agcattagta tcagatattt acagtatgag aacagatgtg acagtcattg cttacgatac
    11701 gctagcctac cgatcaaaaa atatttatgt tggagatatc gaaaaagcag agaaagttat
    11761 ctgtacttat tacgatacac ccgttcatgc attaggaagt tatttcatgt ttgattggaa
    11821 agaccaaagg aaaaaaacaa tctactctat attattgtcc ttcattttgt tgttcagttt
    11881 aggttggtgg ggaatgatga tatataacaa aaatcctcat cacgtattcg atctgctatc
    11941 cgtataaaca ggtatcactg tactagcatt tgggagctac tttttcttat tgggaaaagc
    12001 agctcgcgga tggcctagca gacaaacttt tattcgaaat acttcatcca tattaacgat
    12061 gctagaaatg atccgtacga ttgatgatcc gagtgtagcg tatgcgtttg ttgatgaagg
    12121 ctgttatgga gaaaagggct tagacagcgt gagatcgggt atgaaaaaag aggctattct
    12181 tttttatcta gactctgttg gggcagatac accgctacag ttttcgggaa attatttttc
    12241 aaataaagaa cagtggctga aacaagttga taagttgaaa gaaaaaaacg tcaattatat
    12301 ttttagtgca agaaaaaagc aagcgcagtt cttctatttg accaaaacag atttacgagg
    12361 gaaaacattt aattggcaaa atgccaatca gattattgct ctttttcgat aagtaaaaag
    12421 tgcaaaacaa ggagtgagaa gactaatgtt ggaaatcatg atcgttacac atggtaagtt
    12481 gagcgaagga ctgaaagatg cggcggaagt aattgtcggg acatcgagcc atattgaaac
    12541 aatgtgctta gagtctgggg aggacatcca aacattcgga gagaaggtca aagaaaaatt
    12601 aactatgatc aacacagcag aacccatgct agtatttgtt gatctaatta gcgcaagtcc
    12661 gtacaatcaa gcgctcttgg cagtcaatga actgactgaa gaaaagaaag cagccactta
    12721 tgtcataggg ggcgtgaatc tgccaatgtt gttagaagca atcaatcatc agatgcttca
    12781 cacaccgata gaagaagcgg tggaacaaat tgtcaaacaa ggaaaagata atttaactgt
    12841 ttggcatgct tcagcggaag aaaaaaaatt agatgaggac gatttttaga aggaaggctg
    12901 aaaagatgaa gtggggattt agatggtatg gtgaaaaagg ggattcgatc ccattaaaat
    12961 atgttcgcca aataccggga ataaatggga taattggaac tttgctgact aaaatgcctg
    13021 gagatgtttg ggagatttca gaaattgagg agttgaaagc atctgttgag agccaaggac
    13081 tggaactgct tggaattgaa agtgtagcga tccacgatgc aatcaaggca gggacagatg
    13141 aacgagatta ctatattgat aactatatac gaacaatcaa aaacttgtct cgatgtgggg
    13201 ttcgattgat ttgttatagc ttcaaaccaa tttttggatg ggcgaaaact gatttgttta
    13261 atgaaaacaa cgatggaagc tattctcttt tatacgatca gaaaatcgtc gatcagatgg
    13321 agccaggaga aatgtatcaa ttgatacaca gccagtcaaa gggattcaaa ttgccgggtt
    13381 gggaagaaga acggttgaaa aaattcgctc agctggaaaa actgtatgaa ggaatgaccg
    13441 aagaagaatt atttgaaaat ctgacttatt ttttagaaaa agtgattcca gtgtgcgaaa
    13501 aagcagatgt aaaaatggct atccatccag atgatccgcc atgggaactt tttggttttc
    13561 ctagagtgac gaaaaatctt ggcgacttga agaaaattct aaatgcagta gattctccat
    13621 ataatggact aacgctgtgc acaggatctt taggggcaaa tccggaaaac gatttagttg
    13681 aaatcatcca tgaggtaggt tcgcgcatcc attttgtcca cttcagaaac gtggagtttt
    13741 taggagaaag aaagttcaaa gaaacggcac atccctctac agaaggctcc cttgatatgt
    13801 atcatattat gaaagcgttg gtgcaagaag ggttcgacgg tcctatacgc cctgatcatg
    13861 gtagaaccgt gtggggtgaa gtggctatgc ctggatatgg cctgtatgat cgtgcaatgg
    13921 gactcactta catgcaaggt ctatatgagg cgataagtaa ggaaaaacca ctgggagagc
    13981 attatgaata aaatcaagct cttcatcttt gatatggatg gccttttatt agaaactgga
    14041 cgtttagctt atcgtgctta tgtaaaatca gcacaaaagt atgattatga aatgcgtaag
    14101 gaagtctatt atttactaac tggccaaaca gaaatggcga taagagaaca aatgggcatt
    14161 ttgtacggag aagatgttcc atatatcaaa tggcgagaag caatcaatca atataaagaa
    14221 aaaatcgtga aagaagataa gagagtatat acgaaaaaag gagcagaaga aattttatct
    14281 tttgcaaaag aaagaggaat ccatacaatc gtggcttcgt ctaatacacg ggtaaaagta
    14341 gaaatgtatt taaaaatgga aaatctatat gccttgtttg atcaaatcat ttcaggggat
    14401 gatgtaaaaa aaggaaagcc ggaaccagag atctttttga aagcttgttc aaaaatgaat
    14461 attcctccaa gtgaagcact tgtatttgaa gactcgattg cagggatcga agcagcaagg
    14521 cgagcgggca ttttgtcttt tctcatcaaa gatcatttga tagggttgcc cgatcataat
    14581 gggaagcata agttgaaagt agatgtaagt ttatatgaat ccaataaagc agactatgaa
    14641 ttttatgacc tgcatcaagc aaaacgattt ttagaaagta aagggttgta tctctaataa
    14701 agaggactat tttctagtcc tctttattta ttgtcctgca cgactgaggg aacagatgaa
    14761 aaagaagtaa ttttttattt tgaagtatct accttatttg tagtgaacaa tttagaacaa
    14821 acacaaaacg catctactgt tatctaccag tagatgcgtt taaagagaag aacgagaatc
    14881 gtccatatga gggtttccac tccttatgca gattttttta attcttgcac tgcttgttcg
    14941 atcgtaacac ctgtcgctac atgattggta ttttctttgt caaaaacgac aaatagattc
    15001 aaatctgtat ccaaggttac tcgatattgt atatctttgt tatagaatgt catagccatt
    15061 ctcctttctt taaatacttg ctgaaaggca acgaacgcgt tgataacgaa attccattta
    15121 taagtatacc accaattgaa aggttttcat agttaagaaa ttttaaagtc aaaagttgca
    15181 gataaaagca aataaacaag aaaacaaaaa gtgaatcaat cgcggttatt caactttttc
    15241 ttcgattcga agacaataga agacaatgaa ttttatattt cattgcatta tccttgtgtt
    15301 attagaaaaa gcatgatata ttaaatgagt aatctatttt gaaacgtaat ttgagcgata
    15361 tatctacata gataaaactc cttttgccta tcaaatattt attgcaacga aaaaacgtac
    15421 attgatacgt atcaggagga atttatttat gaataacggt acagtaaaat ggttcaacgc
    15481 agacaaaggt tttggcttta tcactggtga agatggaaat gatgtatttg cacatttttc
    15541 agctatccaa ggtgacggct tcaaaacttt agaagaaggc caagcagtgt cttacgatgt
    15601 tgaagatggt caacgtggcc ctcaagcaac aaacattgtt aaagcttaat aaaaattgac
    15661 ttttaaccgt cttttcgaaa
//
LOCUS       DAKCAA010000057        15184 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000057 DAKCAA010000000
VERSION     DAKCAA010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.057"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(177..2216)
                     /locus_tag="OUE31_002071"
     CDS             complement(177..2216)
                     /locus_tag="OUE31_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HCU0223057.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDQYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2274..2831)
                     /locus_tag="OUE31_002072"
                     /pseudo
     CDS             complement(2274..2831)
                     /locus_tag="OUE31_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            complement(3370..3576)
                     /locus_tag="OUE31_002073"
     CDS             complement(3370..3576)
                     /locus_tag="OUE31_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223058.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(3592..4206)
                     /locus_tag="OUE31_002074"
     CDS             complement(3592..4206)
                     /locus_tag="OUE31_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HCU0223059.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(4353..5036)
                     /locus_tag="OUE31_002075"
     CDS             complement(4353..5036)
                     /locus_tag="OUE31_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCU0223060.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(5145..5603)
                     /locus_tag="OUE31_002076"
     CDS             complement(5145..5603)
                     /locus_tag="OUE31_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HCU0223061.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(5687..7450)
                     /locus_tag="OUE31_002077"
     CDS             complement(5687..7450)
                     /locus_tag="OUE31_002077"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HCU0223062.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(7671..9131)
                     /locus_tag="OUE31_002078"
     CDS             complement(7671..9131)
                     /locus_tag="OUE31_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223063.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(9339..10265)
                     /gene="glsA"
                     /locus_tag="OUE31_002079"
     CDS             complement(9339..10265)
                     /gene="glsA"
                     /locus_tag="OUE31_002079"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HCU0223064.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(10288..11715)
                     /locus_tag="OUE31_002080"
     CDS             complement(10288..11715)
                     /locus_tag="OUE31_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0223065.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(11746..12960)
                     /locus_tag="OUE31_002081"
     CDS             complement(11746..12960)
                     /locus_tag="OUE31_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HCU0223066.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(13301..13543)
                     /locus_tag="OUE31_002082"
     CDS             complement(13301..13543)
                     /locus_tag="OUE31_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCU0223067.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(13575..14132)
                     /locus_tag="OUE31_002083"
     CDS             complement(13575..14132)
                     /locus_tag="OUE31_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCU0223068.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(14145..14333)
                     /locus_tag="OUE31_002084"
     CDS             complement(14145..14333)
                     /locus_tag="OUE31_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCU0223069.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(14346..14912)
                     /gene="amaP"
                     /locus_tag="OUE31_002085"
     CDS             complement(14346..14912)
                     /gene="amaP"
                     /locus_tag="OUE31_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCU0223070.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4354 a         3147 c         2510 g         5173 t
ORIGIN      
        1 ttttattaag tacacttatt tctccacttg ttctcaaata ttttacaaaa aaagtttatg
       61 aagtgtgagt aaatcaaaaa gaagttgtga aagagacatc gtgaaaaccg tttatttgaa
      121 aaaaggactg tgacgataac gccacagtcc ttttactgta cttaaaaagc aattttttat
      181 tgataatttt ggttgaggta ttgcaatagt tccgatgctc gtttggttgc tgaatcatca
      241 tcttctttat tttccaacat gctgaccatc atataacctt ggttatcaag attgaaagca
      301 aacaagaaac tgttctcttg cccctttaca tcctgttttt ctttgatttc cgctgtacca
      361 gttttcgctg ccaacggaat ccctaaagca gaaagagaat gtgctgtacc atttacatct
      421 tgcacaactt ctctcagatc tggcacgatc gtttgtactg ctgtttcgct gatgacattc
      481 ttcttatctt ttgtctcttt atctgcaatc aatttaggat agacaagtgt gccattgttg
      541 gtaaaaacag aatacattgc tgcttgctgg ataggagtaa ttagaagttc gccctgtcca
      601 tatccagtat cagctagcaa gatatctgag ttaaagctat cttcattaga aatttgtgct
      661 ggattcatac taattggcaa atcaaggtct tcaccaaaaa tgaatttatc taagcctgta
      721 cgaaattttt tctcacccat tttcaacgtt tcttgtgccg catatatatt atcggaatag
      781 atcaaagcag tttttaagtc tacttgtgat acatcactac tgacacgcgt tgttttaaaa
      841 gatccccaag aactgtcttt ttgccattta agcccgttga tcgtcaacac ttcatttgga
      901 tcgatagtgc cgttgtcgag accgattgct gctgtaatta ttttaaacgt agatccagga
      961 gcataacctg tcgcaaatcg gctgatgaat ggatgttcag gattttcttc ataagctttg
     1021 taatcttctt gtgagatccc gtttgtcatt ttgtttggat catagcttgg agagctagca
     1081 agcgcaagaa gatcaccggt ttttggcgtt gtcgcaacag ttgatccagc ttttcctcct
     1141 agactgtcaa aagctgtttt ttgtgccttc gcatcgattg tcaatttgat atctttgcca
     1201 ttttgaactt catgttcgat cagaactttt ttctctacac cgtctgcatc tgtaatgctt
     1261 aatttcccac ctgttgtccc acgaagatcc ttatcaaaag ccatctccaa acctgagcga
     1321 ccgatttttc cattactgct taattctgga ttcttatcaa tatcttctgc tgtgatatct
     1381 cccacgtaac caatcagctg agcagctgct tcacccaaag gataatatct gccgtctact
     1441 tcttgaatgg tagctccagc tggaagttct ggcgttgctc catcaatgat tttcaatggg
     1501 acaaagtaat cgggttgtac ccagctttgt gaaatcgcct gattgatagc atcttctgtt
     1561 aagtcgaagg aggaagcaat cgctttgata ttggctgttt tttcgcctcc atctccaagt
     1621 ttacttggaa cgactcctaa ttgttttagt ttgcctgttg ttgctaatgg ttcaccattt
     1681 cgatctataa tattccctct tgctgcttct tgtgtggtca ggcttacttt gtcatttcct
     1741 tccatttctg gaaaaaccaa gttgggttgc cagttgatcg tggtttgacc atcatttctg
     1801 tctaatgttc ctttataaga aagatctttc aattcaccta atgaggtatt catctttgct
     1861 ttatatgaaa aactgtaagt agaatcgtct tttttatcta cttttagatt cgatatctga
     1921 agtcctttga catcagcagc accgtatata ttctggtatt gatctaagat ctctttttca
     1981 gataatgcac ttttatttgc cgcctttttt gatgtcattt ctgcagcttt gttataatct
     2041 cccttgttca aagcttggac aaattgctca actgtctttt ctccagcttc tactgcttgg
     2101 gtttcttgat agtgctggta gtaaaaataa ccgccacccg cagctgctat taagatcact
     2161 gcgccggcaa tataagcgcc tgttcgattt ttgccgtgct tgtcacttct tttcattttt
     2221 tcctccttct cttgcttgtc attcctttat ttcactattt atacctgttt attctaacat
     2281 atgtctttga ggaaatccat accacaatcc agaagcacac tttctggaag gttcgtttgg
     2341 atactaccaa gtaatttccc aaccgctttg ggtagcttga atattgaagt tacgtctttc
     2401 agctgctgag agatagcttt gatcacttgc tgctgccttc tgatcctccc gaagtctcct
     2461 tctttgtctt cccgaaatcg agcatactgg agtaaagtat taccatccat cacttgctct
     2521 cctttgttta tatatacgcc atctaaatct agagattttt ctgcatcgat cttgactcca
     2581 ccaggaaaca gttcattaac gcaatcgata aaatcttgaa atgtgatact tgcataatag
     2641 ggagcttcaa atttgaaatt ttcctttaat gtttgattta ataaatcaac tcccccataa
     2701 gagtaagctg catttatctt attcattccg taacctggaa tatcgacata tgaatctctc
     2761 atgatagaga tcagttttgc ttgttgtgtt ttctggttgt attgtgcaac cagaagtgaa
     2821 tccgagcgac ctccaccaat cgatcttttt tcaccgcatc tcctcctcac acagcaatcc
     2881 acttgtcagg tgaggagcga gtttgtctca tcaaataagt cagtcacaaa aatataaaga
     2941 aaaggtcaga aaccttttcg aacaagaatt ctgacctagc atcatctcat cgtccgagtt
     3001 ttagcactat acaacgtaaa gaaaacattc ttagctattg gaaaaagcct taatccaaca
     3061 gtttctgttt tacccattgg cgactttcga cgtttctggg caacagccta tgtttgtata
     3121 ggagcctcac ctaacaaggt tattactata ttctatttac gagttcatga tagacttttc
     3181 ctaatgatta ggcaatggaa tttgaaatga aatagtgaaa tttaacaatc tttaatattt
     3241 tttagaaaaa aataacaaat aagttgaaag aatcccgttg caaattcttt cagttgcacc
     3301 aggattcttt gataattttt tagttttatg tgttttttta tatgtttttt cacttttcgg
     3361 aataaatatt tatttgttaa agtaattaaa caatccgcta atcgtttgat ctggcatttc
     3421 tatttcctta ccatctaaag taacagtagt aacgacaaaa tggtcttgca atggcggaac
     3481 ttctaagtac tgcccttgca gaaaatcatt cactgtttca tattcttttt tcatttcttt
     3541 tgaatctgtc gatggtttat agcttatttt taacataact agtgctcctt tttattcggg
     3601 acgtgcaatc gtgaaaattt ctcctattgc tgcataatca tttcctgcca aacggcttac
     3661 agcattcaat tttcttggat cgatccttcc tgtcttatca tcatagactg tttcatttaa
     3721 atgatatttc tgtacttcta gcaaaaataa atcagctgtt actttatttt tattccgtat
     3781 ctcgacatgt tcatataagg atgtttcaaa acgaactttt gcttctgtca atgctggtac
     3841 tgaaatgatt actgaatcag ttaaagtcaa gtcagtcagg tacagttcgc tttcctcatt
     3901 aggcagattg gctgctgttt tatttacttc ttctacgttg tcctcatcaa ggatatggat
     3961 aacagcttct cttgtctcaa gaatattctt tgctgtgtct tttactgcat cttgttttct
     4021 ctggatcgcc aaggataaga tgggtcgatt cgaactgacg atattgaagt aactgaaggg
     4081 tgcgatattc actatatctt ttgctgattt agtcgttact actgctactg gtctagggat
     4141 gactgaacca atcagcaact tgtaattttc acgttctgtc aattctgaag gactccgttc
     4201 aaacatggtt tcgccttctt tctataaaat tcgttaaaaa gcagatcttg aagacaaaat
     4261 gaaaagtaat gcttttttca tcttcttaga atctgcttta aactatctat caatttttct
     4321 tttttgtcaa gaatctgtgc cgtgcgtgtt ttttagttat ttgctttact tgcggcttcg
     4381 acatatcttt tagtgatcaa ttgcggacgg gtgataatag atccaactac gactgaaaaa
     4441 gcacctaatt catatgcttt ctctacttgt tcaggagagt cagtatgtcc ttccataatt
     4501 actgggatat cgacttgttc tatgatttga ttcaataaat caaaatcagg tgtctgcgtc
     4561 tttcgtgaat attctgtata gcctgctaaa gtcgtagaca aaagatcaaa accatcttct
     4621 tgcgcttgaa gcgcttcctc aaaagtcgaa atatctgcca tagctaaccg accgtgttcg
     4681 tgaatcattt ggacaagttc agcagttgtt ttttctgtcg gacgtttacg agaagttgca
     4741 tccagtgcaa tgatttctgc ttgcgtctcc aaaagttctt ccacttcttt ttctgtcgca
     4801 gtaataaaca cttctgaccc atcgtaatct cttttgataa tccctattac cggtaaatca
     4861 acgattcgct tgatttcatt gatatcttct gtcgtatttg ctcgaatacc aactgctccg
     4921 ccttcttttg cagccaaagc cattctcccc ataataaaag aactgtgtag cggctcgttt
     4981 tccaaagctt gacaagaaac gacgactccg cctttgattt gttccagtgt atccacaata
     5041 tctcctccag taatgttata taaaaataca gcttcatata aaaatgtaac ccttttctat
     5101 tcaggagaca ataatgagct atttctttca gcagaccttt cttactaaaa gaaaattact
     5161 tcaaattctt cgtatacgac cagcttctct tctgtaaatt ctatgttcaa cgcttcttta
     5221 taagcatgtt taaaaaactc agcatggact ttccgccaat aagctaatgt ccgatcccct
     5281 tctccttctt tccaagcatg ctctttcgtg acttcactaa aaggcaagat ggtcacattt
     5341 atatttttga tgatacaaac tggttcattt tttccattca ggaccacgtc taattgacca
     5401 acttttggta aaggctcatt ctcttgttta tacagatcgt aaccacttga tgtaccagtc
     5461 tttatctttt ttacaactag ttcgctcaac tcgtctgcca ttttttctgt atccccaaat
     5521 gaaaagaaac ctaatttttc tgattgataa ctaggatatt tttcttggaa ctttttgaca
     5581 tattcttcta cttgctgata cataacatcc acccctttgc tttttataat gaaaaaacca
     5641 tccagatact agtataaaca attatctgga tggtgagcat aatgaattat tgaatattca
     5701 agacacgcag actatcttca acgatttgtt ttggtgttaa atgataacgt tcataaagct
     5761 gccctacagg aacgctatcc gtgaattctt tctctgcacc aaaatttaat acgttcattg
     5821 aagaatcacc ataataacga ctgatatttt cgccaaatcc tcctgacaaa ctaccatctt
     5881 ctaatgtgat gactaattcg tgtgtttctt ttaatttatc taatgtttct acgtcatttt
     5941 ctgtgatcgt tcctggattg atcaacgttg cttcgattcc tttttttcta aaagctttta
     6001 ctgtttcttt tcctaattca agaaaaccgc ctaaagctaa aattgctact tttcctccat
     6061 tatttactgt ttgataggct ggaatactat aatcatttgc gatagctgta ccatgttcta
     6121 caccatgtgt aggaattcgg attgctacag gctgcgctgt ttgttcgaac gcccaatcta
     6181 gcatagagat catatcctct tttgttgctg gagcaagata tttgatgttc gggatacttg
     6241 ataagtaagg aatgtcaaat gttccttggt gtgttcggtc actagctgag atcgttccgc
     6301 caccgactaa aataatcact ggattctcgt tgatcgctaa atcatgtgat aattgatcat
     6361 atgcccgttg caagaaagta cttgattgga agacgactgg acgtactccc tgagaagcca
     6421 aagcagaagc gaaagtgata gagtgctgtt cagcgatccc cacgtcaaaa taatgatctg
     6481 gatgtttttc ttggaatgtt ttcagtccaa aggcgcctgg tatcgctgca ttgactgcgg
     6541 caataggagc tgtacttgtt tgcattttct tatccaaata atccatgatg atcatattaa
     6601 atgtttctcc agaagttact tgctttgcct ccccggtgga cagatcaaat ggtacatgcc
     6661 aatgatattt cattttatta tcgattgccg gctgataacc gcgacctttt tccgtatgga
     6721 cgtgaagtac aatcggatga tcaatatctt ttacttcttc aaataaacgg atcaccgttt
     6781 ccagatcgtt tccattatcc acgtaacgat aatcaaatcc cattgcttta aataggttat
     6841 tgctgctttt accgttggtt tgacgaagct cagctaagtt tttatataaa ctgccatgat
     6901 tctcatcaat agacatctca ttatcgttta ctaatacgat tagattggat tgtaaaacac
     6961 caccattgtt caatccttca aaagctaagc caccacttag ggagccgtca ccgataaatg
     7021 ctaccacatt tcctgattct ttcttcagat ctctcgcttt agctaaacct gttgctaagc
     7081 tgatagatgt agatgtgtgc cccactgtaa aatagtcatg tttactttca tgttggttgg
     7141 aatatccgct cacttcacgg taatgtcctt tttcaaaacc attttttcga ccagttaaaa
     7201 gcttatgacc ataagactga tgggaaacat cccaaacgat tttatccttt ggtgaatcaa
     7261 atacataatg aaacgcaatc gttaattcta ctacacctag attcggacca acgtgcccac
     7321 ctacatcgct gtccttttgc aagatttttt ggcgcatctc ttctgccaac tgtttcattt
     7381 cctcaacaga taattttttg acatctgcgg ggctattgat tgcatccaat acatgtaata
     7441 ctgtactcat aatacattct ctcctccgta ctatcttctt ttaatgaaaa tagatttgtt
     7501 acactttatc tattctacta cttagagttg actctaagtc aatagcattt taaaaaaatt
     7561 tcagagaaag cttgttatat aagtagatct tcgcacgaat caggactcaa ataaaaacct
     7621 tctacagaca attaaaaagc tttgtagaag gtctcctaat taaggtctca tcaagaaata
     7681 tgttttttta ataggtgaag ttcctgagca atatgataca aatggatgtt tgcacctttt
     7741 aatgagattg gatagatctt tgtcttttca gtttctaatc cattttgata gctagcagca
     7801 tcgcacaaaa ccactctttt tttcgcacat agacattcat caggcaattc ttctaatgaa
     7861 cgaaataaaa taggatttat ttcagcgatg ccttcttccg catacaaatg aaattgggtt
     7921 cgataaaaaa attgtttgac tgaactttct gaaacaacaa aaatttctat ttcctgtctc
     7981 cccgcttgtt cactgttgat caaagaaaga cttttgacga attttcgaat gaaattttca
     8041 ttccatctta gttggatttg atttttcttt ttccactctt ccaatatttc tacaattttt
     8101 ccgtacagaa gttgttcttt ttctgataga agatagatcc tttccggtaa aaatacttgt
     8161 ccatctgccc acaacgtacg gacaaattgt aaaaaggatt gcttgaaaat aaaattttct
     8221 gcatcgtcga tttcagcgat actaataatc tgtaaaatca attcattcag tgataggtca
     8281 ttgagaacaa aatttttata aacaacttcg aaatcttttc ttaacagctc catgttctca
     8341 ttggtataat ttctactgtt gaacaaagaa aaaatataat agacatcttc ttcttgtaag
     8401 tctagaattc ctttttgctc ttccaatcct tgacagacta attgaaataa cggcttcgtt
     8461 tctgcgcttt tcttatcttc ttctttcagt ccaaggggaa atgcctttct tccgattgcg
     8521 atctctattc ctcgtatgat aaaggacttt tcatcttccg aatatcttct tttaaaaaaa
     8581 tgagtctcta cataatcaat caactcgtta caagcttctt ctacatacgg atttttattt
     8641 tcatagcctt cccaattgac ataacgtact aaagctagca agatgttccg cgagtcaaat
     8701 tctgggataa tgatttcttt atttttcaaa taatcatttt ctttaaaaaa atccaatacg
     8761 atttttttga ttgtatatac tttgctcaaa gaaataaatt caagatcagc cagttctgta
     8821 ctcgtgaata taccattaaa ataataactt aaaaacttta aaaaataaga ttgaccgtac
     8881 agaaactgtg tgagctcaga aagagcaata ccatgtttga atacgagttt atacttatgc
     8941 ttctctctta cttgttcttt tatacaatat tctagacact cggctagact ttctagatcg
     9001 tgaaggatcg ttggtgtagt cacccttaga gaaatagctg tttgttcgat gtctatttct
     9061 tggaattcaa ataattgttc acacagatac acttttctaa atatatttcg ctcgatgtaa
     9121 ttttccagca ttcctgatac acgcctccag tttttcttat gattttattt aatcatatct
     9181 gtaaatcgta tttttgtttc ctttttattt agaaaagccc tttcaaaaac caataaaaaa
     9241 agaaactggg acaaaagtca aacaagctca caatttcagc ctcattgtag gtagctttga
     9301 gccgtttgga cttttacccc agcctctttc aagaatggtt attcaaagat gtcagcgtct
     9361 agttctttga ctacatcttt caacaattgg ataccagctg cgctgttacc aaatggatct
     9421 agtgccgggc tgaagacacc tatgccgtaa cgatttggca cagctgccat caacccgccg
     9481 cctacaccgc tttttgcagg tacaccaaca tggacggaaa actctcctga ttcatcatac
     9541 aaaccagcag ttgtcataat tgatttgacg attgtagcac tttcttcagt aatgatttgt
     9601 ttgccattcc aaggagcaat tcctttattt gccagcacag cagctaattt tgctatgcct
     9661 gtagcggtga cattgaggga gcattgtctg aaataagcat cgagtatctc cggtacgtct
     9721 ccttcgatca tttgattacc tttcatatag taagcaagag agcgattgat atcacctgtt
     9781 cttgattcag aatgatagat ttcttcattc aatgtgatat taggatcatc acagatctct
     9841 ttcataaatg acaagattcg ctcaaatttt tcatctgcat ctttaccggc aatcaacgag
     9901 gttgttgcaa tcgctcctgc attaacaaaa ggattcattg gatgtttgcg atgattgatt
     9961 tccatattca tgatagaatt gaaggcaaaa ccggttggtt ccgtgttgat tgtttgaaag
    10021 actttttcta ttccgttgtc tttgattgct aataacaata cgggaacttt tgacatgctt
    10081 tcgatggcaa agcgcacatc ggcgtctcct ccctcaatca gttgttttgt atccaaatca
    10141 taaatcgcca tacctaattg tttgggatcc acttcagcta atgctggaat gtaatccgcc
    10201 acttgtcctg tttgataata gtggaaattt tttccaatca attgttctaa ttcttttact
    10261 tccatttgaa taaccagctt tcatttttta tttttctgca tgctggaatt tatgacggca
    10321 tgcgtagatc gtaaatggaa taactaagac gataagataa gaaacaatca gaatcgtttc
    10381 ataaatccca tgctgtccag ctgcgatact agcaggtgga acaaatgaga tacaaaaagc
    10441 aaaaagtgaa gtcaaaagac ctaaacaagc aacgattact tttacaactt ttccgcctgg
    10501 aacctgatag gctctttcaa gactgtcatc tttaaaaacc agcttcaaat agcccgcgaa
    10561 aaacataaag tacaacatca ggtagattac aacagtcaat gacatcgctg caagaaatga
    10621 aagattattc cccccgccgc ttaatgtaaa gacggctgcc cagattgttg caacgatccc
    10681 atttgcgatc atcaaatgag caggaacacc gtgtgtgttt tcttttgcaa aatattcagg
    10741 aagtaatcct tcttctgctg ctacgtgaag tgcttttgaa ggagaggtta cccaagaagc
    10801 aatttctccg atgacaccta aacaaacaag aatcgcaaga attttcgcaa tccatgcaag
    10861 atttggatca atgtgtctta ataggaattc taacgattga atcacccctg tattaagaga
    10921 caaaccatgt tgaggtactg tagtagcgac ggtcaatccg ccaaaagtat ctaaaatgat
    10981 tgccagaata accaatacaa acattgctaa tggataatcc tttttagggt tttccatttc
    11041 atttgcatga ctggcagatg tttctacgcc catatatgct aaaataaagg aaacaaaaac
    11101 aaccagcgta ggcaatttcg aaaaatcagg aatcaatgtt ttcatagaca gtatcgtttg
    11161 tagtggagcg cctgaagcga cataatggat ccctaagcca aacaagacta atgctggcaa
    11221 caagatacca gctacaaaac cgatccgagc aatcaatgaa gtgtatttgg ttccttttaa
    11281 ctgtgagagt aaaatagccc agaaaataat caataggatt gccaatttca gatatttatt
    11341 gttttgtata gcaccaatac ccgttgcata ggataatgca ccagttaaga aatacagcat
    11401 ggtcaagtag ccaactgtta tctcaaacca ttggaaaaag attgcggcaa aaccgaatcg
    11461 ttttcccaat gtgcgactga cccaagtata gacaccgcct ttttcccatc ctttcaccgt
    11521 tgccatctct gctgcgcaca atgccacagg gataaaccat agcaaaccgc ctaataacaa
    11581 gaaaaatact aagctgaagc ctgaggtcgc gaatgtggga tattcatata atgaaacgac
    11641 cattgagatg gtcatagcca aaaagccaaa gaacgttaat ttttttgcag gaattttcgt
    11701 tttgctttgt tgcatgaatc ttcctctttt ctatttgaat ttgtttcaat tgagtttgtt
    11761 gccaaagaag aaaaagtcca atccttcttc ttgttcttct tttgtagtag tgatcgttgt
    11821 aaagtgcatc gccgatttta aaatcactgt tgtcagcaca taggcataca cggcagtaat
    11881 gatgacacca atcacttgaa tccctaagaa gtaccagctg cttggattcg ttagtaaatg
    11941 gctgttagat gcaaagatcc ctatcagaat cgtacctgtg aatccgccca tgccatgaac
    12001 accccacaca tcaagtgcat catcccattg tttcttttta cgaaaatcaa cagcagcatg
    12061 acagacgata cccgcaatga tcccaatcag catggcactt tttgcttcta cataaccggc
    12121 acaaggcgta atggctgcca atccagcaac ggatcctgtt agtacgtcga caaaatcaaa
    12181 gccatttcct tttacttttg caatgatcag ccaagtaatc atcgcaaatg caagagcgat
    12241 gaatgttgaa ccaaatgcat tgactgcttg ttcatctgct cgaagtgcac caccggaatt
    12301 aaaaccgaac cagccaaacc aaagcagtcc tgtaccgata gcagctgcca taagactgct
    12361 atgctgactt ctttctccta aaggaatctt tctttgacca agtgtgagga tacatgctaa
    12421 agagccgaat ccagctgtcg tgtggatgac tgctccacca gcgaaatctc taaatcccat
    12481 ctgatccaaa aatccgccac cccatatcca gtggcaaaca gggaaataaa tcagcagatt
    12541 ccaaaaaata acaagtataa tatagccttt taaattcaat ctccctgcaa aagctcctgt
    12601 catcaaagga acggtaatca cgataaacat cagttggtaa agaaagaaca ttaaaaatgg
    12661 aatcgttgca ccatgaaaca tgttggggaa gcttgtaaca tgtctcatca aaaagaaatc
    12721 tgccgggttt ccaataacac cgccgatatc ccgtccaaag gccaatccga atccaccaaa
    12781 tacccacata atcgttgtta tcccaacgga gagaaaagat tgagacatga tcgttagtat
    12841 attattcttc cgtgctaatc cgccgtaaaa aaaagctaga ccaggagtca tcaggcaaac
    12901 cattgctgta cataaaatca tgaatgctgt atctcctgta ttgataggta atgtattcat
    12961 ttttttcgcc tcctttctac gattacgagt ataaaagaag gtgtagttgt ttttttcttc
    13021 tgtttttttg aattaatact tgcatttata aaagacagac aattaataaa agcttgatgt
    13081 gttgtgctct ttttcgtttt tcacacaaat aaagacaaaa aataaacggt cttcttttta
    13141 tagaaaaccg tttattttcg tcttttttta tttttaaaga tattttttca taaggaataa
    13201 agaatacttc atataaaata tataaaaaag aaccgcagcg agtgtcgcta cggttctcaa
    13261 atttgttctt catttcaaca taagtttttc ttcaatttgc ttataattta cgtgcaaaga
    13321 atgaaacgac taatactaaa atgattgcac cgatcaatga tggaatgata gccattcctg
    13381 caattgttgg tccccaagtt cctagtaaag cttgtccaat tgctgaacct actaaaccag
    13441 caatgatgtt tgcgatgatc cccattgatg atcctttatt cgtgattgct cctgcaattg
    13501 ctccaatgat accgccgacg attaatgccc aaataaatcc cattttaaat tcctcctaac
    13561 tgacttctta cttcttattg tacacgtggt tcgttatttt ctttgacttt ttgtgcacct
    13621 ttgcctacag cagattttgc tttatctgtt tggcgtgaag caaattgtcc tgtggatttt
    13681 gctgcttctg ttactttgtc ttgtactgtt tcttgatctt tttggtattc ttcttgtgtt
    13741 ttgatgtctg caacattcac attcacttcg ataacatcta aatgtgtcat attgtttact
    13801 tcagtactga tcaattcttt gatttggttg taaatatctt cgatgtcttt accgtattct
    13861 acgatcacat ctagatccac agctacttgt ttcttaccta cttctgtatt gatacctgct
    13921 gttacgttat ctgtgttgac taatttttca gccatatttg agaaaaatcc gccatctaat
    13981 gtcaatagac catctacatc tttcaatgca taaccgatga ttttttggat gactttgtct
    14041 tcataagtca attcaccatt catcatgcgg ttttctcctt tttcatttgc caaaactgat
    14101 ccatttgttg tattcatgtt tttgttttcc atctttgttt cctcctatga tttaaaaaat
    14161 tgatcaacta ttcctgactg tttcaaataa aaaccgattc ctgcgccaat tgctgtcatg
    14221 attatgatca acaatgtctt gaaaaatcca atcgttaacc ataaaacagc tagcagtagt
    14281 ccaagacccc caaagataat agggagcttg tatgctgaaa atagttcttt cattatttgg
    14341 ccctcctatt ccactcgaga gtgcttgtag tctcttgtat cttcttgttc ttcataaccg
    14401 ctgtatgtga ctgccacttt gaccgtttct tttgttccga gtactttagt tacttcttct
    14461 tcgatatctt gcatcaatac acctgttttc cctactaatg aagaagttcg tttcaagtct
    14521 ccgttgacat ggatatggat tcgatttttc gttgaacgta tccgtacttt aggtgaatga
    14581 atgaactctt cttcgtgtaa atgggaacgt accaaccctt cgatcgcttt tttgtcgatt
    14641 gttagtttgc catcttcccg tttcataacg aaagttcctc ttgactttgg atagaaaaga
    14701 acgactagca agatgataat agcaagaacg gcaaatacta cagctgccca gaaaatatat
    14761 tgttgcatgt agtaattcgt taaagtaaag aagcgaaatc gttccaattg ttcaggcata
    14821 atatacggcg cattgatcaa cgcaatcgct agaaatactg aaagtagcag taaactcatg
    14881 ataacaccga ttatttttaa ccccttattc attttccacc tcctataaac ttatttttac
    14941 cctgtaaata actctaccga caatcacagt atagatagcg aacagttagc atagcatcag
    15001 taaataaagc gctaccaaac attgctggat cataacggcg ttttattgcc agtctgatac
    15061 tgaaataaca attgcttact tattctctat ttacttttga ttgctggcta tacttaaagg
    15121 atattattca agattaaaaa ttgcaaagat tatgctcagt tattattaca agattctatt
    15181 tatt
//
LOCUS       DAKCAA010000058        15094 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000058 DAKCAA010000000
VERSION     DAKCAA010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.058"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(21..1586)
                     /gene="guaA"
                     /locus_tag="OUE31_002086"
     CDS             complement(21..1586)
                     /gene="guaA"
                     /locus_tag="OUE31_002086"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCU0223071.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(1645..2568)
                     /locus_tag="OUE31_002087"
     CDS             complement(1645..2568)
                     /locus_tag="OUE31_002087"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCU0223072.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            2764..3369
                     /locus_tag="OUE31_002088"
     CDS             2764..3369
                     /locus_tag="OUE31_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCU0223073.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            3677..4693
                     /locus_tag="OUE31_002089"
     CDS             3677..4693
                     /locus_tag="OUE31_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCU0223074.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            4834..6135
                     /locus_tag="OUE31_002090"
     CDS             4834..6135
                     /locus_tag="OUE31_002090"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCU0223075.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            6181..6843
                     /gene="deoC"
                     /locus_tag="OUE31_002091"
     CDS             6181..6843
                     /gene="deoC"
                     /locus_tag="OUE31_002091"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCU0223076.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            6864..7262
                     /locus_tag="OUE31_002092"
     CDS             6864..7262
                     /locus_tag="OUE31_002092"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCU0223077.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            7328..8410
                     /locus_tag="OUE31_002093"
     CDS             7328..8410
                     /locus_tag="OUE31_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCU0223078.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            8622..10184
                     /locus_tag="OUE31_002094"
     CDS             8622..10184
                     /locus_tag="OUE31_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0223079.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            10177..11310
                     /locus_tag="OUE31_002095"
     CDS             10177..11310
                     /locus_tag="OUE31_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0223080.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            11310..12266
                     /locus_tag="OUE31_002096"
     CDS             11310..12266
                     /locus_tag="OUE31_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0223081.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            12365..13531
                     /gene="deoB"
                     /locus_tag="OUE31_002097"
     CDS             12365..13531
                     /gene="deoB"
                     /locus_tag="OUE31_002097"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCU0223082.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            13555..14373
                     /locus_tag="OUE31_002098"
     CDS             13555..14373
                     /locus_tag="OUE31_002098"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCU0223083.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            14390..>15094
                     /gene="deoD"
                     /locus_tag="OUE31_002099"
     CDS             14390..>15094
                     /gene="deoD"
                     /locus_tag="OUE31_002099"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCU0223084.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT         4706 a         2797 c         3397 g         4194 t
ORIGIN      
        1 gatttctagc tctcctacaa ctattcccac tccactgttg ctggtggttt agaagtgatg
       61 tcatacacga tacggttgac gtgggctact tcgtttacga tacgtacaga gattttttgc
      121 aagacttccc atgggatacg ggcaaagtca gcggtcattc cgtcgattga agttacagca
      181 cggataccga ctgtgtagtc gtaagtacgt ccgtcaccca taacaccgac agagcggatc
      241 cctggaagaa cagtgaaata ttgccagata tcacggtcaa gtccagcagc tgcgatttct
      301 tcacgcaaga tagcatcaga ttcgcgtacg atttctagct tgtcttcagt gatttcgcca
      361 agaacacgaa taccaagacc aggaccaggg aatggctgac gccaaacgat tgaatcaggc
      421 atgcctaact gagtccctaa ttcacggact tcgtctttga ataatgtgtt taatggttcg
      481 atcaattcaa attgcatatc ttctggcagt ccacctacat tatggtgaga tttgatcgtc
      541 tgtgctgttt ctgtaccaga ttcgataacg tcagtataca acgttccttg tgctaggaaa
      601 gagacgcctt cttcaccagc aagttttgtt gcttcgtcat caaaaacata tacgaattca
      661 ttcccaatga ttttacgttt ttgttctggg tcagatacac ctttcaactt gtctaagaag
      721 cgatctcttg catcgacttt gatgatgttc aagccgaatt ttccgcctag actttccatt
      781 acttgttccg cttcgccttt gcgtagcaga ccgtggtcaa caaagataga tgtcaattgg
      841 tcaccgatcg ctttttgtaa aagaacccca acgacactag aatcaacgcc acctgaaaga
      901 ccaagcaaga cttttttgtc accaacttgt tcacggattt tttctacttg catatcgata
      961 aagttatcca ttgtccagtt accttcacag tgacaaacat caaaggcaaa gtggcgcagc
     1021 aattcgattc cgtattcgga atgacgtact tctgcatgga attggatacc ataaaaatta
     1081 cgtgttgtgt cttggataga agcaatcgga caatctttgc ttgttccgac tgtttcaaag
     1141 ccttcaggaa ctttagttac caagtcacca tggctcatcc atactgtttg ttgttttggt
     1201 gtttctttaa acaagacagc ttgatcgctt gttacttcta acaaggcttt cccatattcg
     1261 cggtttttag caggctctac ggaaccgcca agtttgtacg tgatcaattg cataccatag
     1321 caaatcccta atacaggaat acctaaattg aagatctcag gatcgatccc aaatgcattc
     1381 tcatcatata cactgtttgg tccgccagaa agaatgattc cctttggatt catcgctttt
     1441 acttcttctg cagtaatgcg gtggctcaat aattcggaaa agactccaag atcacgaata
     1501 cgtcttgtga tcaattggtt atactgacta ccgtagtcta atacgataat cttttcaacg
     1561 ttcgtcatat cggcaacgtt tgtcaaattt attaccccta tccctttaaa ttttatctca
     1621 aaatagtcaa actattttaa aatgctaata ttttcgcatg aaaatcgaat cgatgatatg
     1681 attttcagtt ttatggagaa ttatatcggc tcttcctcgt gtaggcaaga tatattcctg
     1741 taaatttttc aaattcacat ttttccatac atcttttgcc attttaaagg cttcttcacg
     1801 atctccgata gcaaaacgat aataataatt ctctggattt tggaaagccg tatccagtaa
     1861 cgcaccaaaa cgatccaaat accatttttc gatcagcacg ggatcggcat cgacatagac
     1921 agaaaaatca aaaaagtcgc tgacgtagat ttgctgattc gcaggtaatt gaagcgtatt
     1981 gatcccctca acgatcaaga tatcaggctg ctggatcaat tcgtacttgt ctggaatgat
     2041 atcatacaca tcatgtgagt aaacaggtac ttttatctct tcctgaccag attttacacg
     2101 gttcaagaaa tcgatcagca tctccatatc ataactttca ggaaatcctt tacggtccat
     2161 gattccacgc tcttttaata tacgatttgg ataaagaaat ccgtcagtcg tgatcagctg
     2221 aacgtttctt cgtttgaagg tacgagacaa aatcgtctgc agcagtctgg ctgttgtact
     2281 ttttccaacg gctacacttc cggcgatccc gataataaaa ggcggtactt ctacgtattt
     2341 atgaagaaat aaacctttac tcaagaacaa agattcaaat tctttcatat aaagataaat
     2401 cagatgagca agaggtacat agatatctcg aacatcctgc atggaaatgc ggtcattcaa
     2461 acttttgata ttatctagtt catcttgtgt caaaggtgct tgcccattac gataaaattc
     2521 tcgccattct tctcttgcca cacggtagta gttcattgga tcattcatat tagcctcctg
     2581 cgttctccca tcaatggaac tattttaaca caaaataaac gcaaacccca ccacttaaga
     2641 gagattgccg atctttttgt ataatcttta taatagaaag aaacggagtc ttattcttga
     2701 cttgcgcacg gatacataaa aggatagact gttgtcatga aagaaatgag aaggatggaa
     2761 gacatgacaa atcattacta ttctgaacgc ccagatacgg cgcacgattt tgaacaatgg
     2821 gcttttgagt taaaaggcag aacctttcaa tttgtaacag attctggtgt attttcacgt
     2881 gaaacagtgg attatggttc acgtgtcctg attgatgctt tcgattggga agagttacct
     2941 gatgaaggaa agatcttaga tgtgggatgc gggtatggac cgattgggtt agctttggca
     3001 tttgcgacac agcggtttgt tgaaatggtc gacattaatg aacgagcggt aagtctagcg
     3061 caaggaaacg caaagcgtaa ccaaatcgaa catgttgata tccatcaatc gaatatctat
     3121 gaagcagttc atgaagaaac ctatgcagct atcgtaagca atccgccgat ccgtgctgga
     3181 aaaaaagttg tacatgaaat tttgacaggc gcatatcctc ggttgaagaa gggcggtaca
     3241 ctgacaattg tgatccagaa gaaacaagga gcgccgagtg cgcaaaagaa aatggaagaa
     3301 acatttggta atgcagaaat cgtcacaaaa gataaaggat attatatcat caaaagtgtg
     3361 aaagaataac tagctgaaaa atagtggagc gacgaaagag tggaactggg cgtgcatgta
     3421 cgggtacgta tcagttcttt ttttgttgag aagtttttaa aaacaaagaa ctattttttc
     3481 ttcaaaaaga aatagtagga acagagtcgt tgttttttac gataaaataa ataagataca
     3541 gaacttgtat agaaggctgc caagtcggta gataaaggag gtttttatca aaaaacatac
     3601 tttccttttt tctctattct tttcttgggg gttttggtac actgataggg aatttagata
     3661 gaagggagcc aataggatga agctgaccat cagagatatc gcagaaatgg caggcgtatc
     3721 agtaacaact gtctcacaga ttttgaataa caaaggaagc agatttagtg ataagacaag
     3781 aaaaaaagtg ttgtcgatcg tgaatgaaca tcattataag cccgattatt tcgcttcaaa
     3841 tgtgatcaat cgacattcaa agaccatcgg aatgatcgtc cctgatgtca ctgatttctt
     3901 cttctccaaa ctgatcgaag gtgtagagag ctatttgaat cctttgggct atgtgatcat
     3961 gttatgcaat tctcgtcata gccaagaaaa tgagatcaag tatttacaag agctttccca
     4021 ccgctcagtg gacggaatct tgctggccac accaaatatt ttacctgaga aatatgcatt
     4081 agacagcggt ttttatcaaa aaatgccaat cattttaatc gatcgcggat tgaatcgtcg
     4141 ggataacgga cggcttatcg taaaggaata tgagggcgcc tatcaagctg tttcgctgtt
     4201 tattgaaaat ggccatacga agatcggcat gctgaaggaa accactggat actatcaatt
     4261 agaagaacgt ttcaacggat atcgtcatgc gctgaaagat catggcctgc cttttaatgg
     4321 gaaatttgtt gaacatggag agttgactgt ccaaggtgga tatactgcat caaaaaaatt
     4381 actcaaacat aaagatatca cggctatttt ttgcgggaat gatgccatgg cgatcggatg
     4441 ctatcaggcg atcgatgaat tgggcaaaaa aatcccagaa gatatctcag tcataggatt
     4501 cgatggatta aagctgtcag aatacatgat tccgcaattg acgacagtgc agcagccaag
     4561 ttttgatatt ggattttatg ctgcacgttt cctgatcgat acgatcgaat ttcctcaaag
     4621 aaaagttccg aacaaagtgt tcgaaacaaa attaattatt cgtgagagcg taaaagtatt
     4681 gacaaagggc taactcggcg gtatattgct tatgtaagca tttacaaagg ctagttagtg
     4741 ctttttttat ttttagtaaa ccagtttact aaagtggttt acctttccta aaaataatgt
     4801 ataataccga atgaagacaa ggaggatcag gcaatgcgaa tggtggatct gattgaaaaa
     4861 aagagggatg gaaacgagct gtcgaaagag gaaatcgagt acatcgtcac gaactatacg
     4921 aatggaaaga ttccagatta tcaagtcagt gcattattga tggcaatttt ttatcaagac
     4981 atgacaaatg aagaaatcac gaacttaaca ttggcgattg ctaattctgg tgatgtcatc
     5041 gatttgagtt ctcttgaagg aataaaggta gataagcatt cgacaggtgg cgttggtgac
     5101 acgaccacat tgattttagc ccccctagta gctagtgtcg gagtgacagt ggctaaaatg
     5161 tctggacgcg gtctaggtta cacaggtggt acactagaca agctagaagc aattcccgga
     5221 tttcagatcg agctttcgga tgaagaattt gtacgcattg ttaatgaaag taaagtagcg
     5281 gtaattggtc aatcaggaaa cttggcaccg gcggacaaaa aattgtatgc cttgcgtgac
     5341 gtcacagcga ccgttgattc tcttccgctg attgccagtt cgattatgag taaaaaaatc
     5401 gcggcaggag cagatgcaat cgttttggat gtgaccactg gagacggtgc tttcatgaag
     5461 aacatcgaag atgcaagacg tctggcaaag accatgacga gcattgggaa actggctaac
     5521 cgagaaacag tggcggttat ctcagatatg tcagaacctc ttggcgaagc tatcggaaat
     5581 agtctagaag ttgtcgaggc aatcgaaaca ttacaaggaa atggtccaga agatctagta
     5641 gaaatgtgct acgccttagg aagccaaatg gttgttcttg ctggcaaagc taagacaacc
     5701 gatgaagcaa gaacgttgct tcaagaagct ctggaatcag gtaaagcgtt agcaaaattc
     5761 aaagaaatga tccaaaatca agggggagac ccagcgatcg tggaacatcc agaacgaatt
     5821 ttgactgcac gctacacaat ggagcttcct gctaaacaaa gcggagttgt gtcaaaaatc
     5881 gtggcaaatg aattaggaat tgctgcaatg atgctaggtg ctgggcgtaa aaccaaagaa
     5941 gaagatattg atcacgctgt tggattgaaa ctgcataaaa aaattggtga cactgtgaca
     6001 aaaggtgagt cactattgac gatctatagt aacgacgaag aaatcacttc tgtcattgaa
     6061 ttattatata aaaatattga aattggtgaa tcggcaatga agccaacgtt gattcatgac
     6121 atcatcacag aataaaggaa aaaagcggac tttaccgttt taaagaaaag gggaaaagaa
     6181 atggaactaa accgaatgat cgaccatact attttgaaag cagacgcatc taaagaagct
     6241 gtgatgcaaa ttatcgaaga agcaaaaaaa taccattttt attctgtctg catcaatcca
     6301 gcatgggttg cgctagcgaa agaacaatta caaggtgagc cagtagccgt atgtacagta
     6361 atcgggtttc ctctaggagc aaacacaccc gagacaaaag catttgaaac aacagatgcc
     6421 atcaataacg gtgcagatga agtcgatatg gtcatcaata tcggtgcttt gaaatcaaag
     6481 gatgatcaac aagtccaaaa agatatcgaa gcagttgttg aagcagcaaa agatcgtgcg
     6541 cttgtcaaag ttattattga aacatcgtta ttagatagag aagaaatcat ccgagcttgc
     6601 gaaatagcaa aagctgcagg cgctgatttt gtcaaaacat caactggttt ctcaacaggc
     6661 ggagcaaagg tagaggatgt ccgtttgatg cgtgaaactg taggaccaga aatgggtgtc
     6721 aaagcttccg gcggtatcca taacgaagaa gaagcaatgg caatgatcga agctggtgct
     6781 acaagaatcg gaacaagcgc aggagtagca atcgtatctg gttcaactgg tgaaggctat
     6841 taattttttc aaaggagaag ctcatggcag aactcaaaca agaatggatc aacacagcta
     6901 ttgaagcgtt agataaagcc tatgttcctt attcccattt tccggtaggc gcttgtctcg
     6961 taacggaatc aggcaagatt tatcaaggca tcaacattga gaatgcatca tttggattaa
     7021 cgaattgtgc cgagcgcaca gcttttttca aagcagtatc tgaaggagaa aaaacattta
     7081 cgcatctagt cgtagcgggg cacacccccg atcctatctc tccttgtggt gcatgtcgac
     7141 aagtaatggc agaattctgt tcccctgata tgccggttac gctagtagga gacaatggtg
     7201 tgacgaaggc aacgaccgtt cgtgcactgc tgccttatgc atttactgaa aaagatctat
     7261 aactcatgtt cattcagtca gctgactgtt gaaaaataaa acaattattt taggaggctt
     7321 tacagaaatg aaaaaagcaa aattatttgg tttaggtgct gtcgcactag cagcagggtt
     7381 atttttaggt gcatgcggca acaacggctc tactgattca tccggtggca aaagctcatc
     7441 agacacaaca actgcagcat tgatcacaga cacaggtggt gtagacgacc gttcattcaa
     7501 ccagtcagct tgggaaggac tagaaaaatg ggggaaagat caaggacttt cacgaggaaa
     7561 tgatggcttc caatatttcc aatcttcaaa tgaatcagat tacatcccaa atattgacca
     7621 agcattgaat gctggattca aaacgatttt tggtattggt tataaactaa aaccagcgat
     7681 ccaagaacaa gcaacaaaca atacaggtac gaactttgtt attatcgatg atgtcatcga
     7741 tggattagat aacgttgtat ctgcaacttt caaagacaac gaagcttctt atcttgcagg
     7801 tgttgcagca gcttatacga ctgaaacaaa cgtagtcggc tttatcggcg gtgtaaaagg
     7861 tgaagtaatc gatcgttttg atgctggatt caaagccggt gttgatgcag gtgcgaaaga
     7921 attaggaaaa gaaatcaaag tattgaatca atatgctggt gacttctctg ctccagataa
     7981 aggacgttca attgctcaag gtatgtatgc acaaaacgca gatatcatct tccatgcttc
     8041 aggcggtaca ggtaacggtg tattccaaga agcaaaatca ttgaacgaat caggcgacaa
     8101 aaaagtttgg gttatcggtg ttgaccgcga ccaatcagac gaaggcgaat acacattaaa
     8161 cggcgaaaag aaaaacttca cattgacatc tacactgaaa gcagttggaa cagtagtaga
     8221 agatttggca caaaaatcag cggacggtaa attccctggc ggcgaacaca ctgtttatgg
     8281 attgaaagaa gacggtgttg gtctaacaga aggacaactt tctgacgaag cgaaaaaagc
     8341 agttgatgaa gcaaaagaaa aaatcatttc aggtgacgta aaagttccag aaactcctga
     8401 agaaaactaa aaccatttct atagccttgt tagacacatg tttgacaagg ctatggtttg
     8461 attagaacaa gaattgttca tttatccaag ctgccttgtg acagtttgga taagggaaca
     8521 actccctgaa gtaatgtttg tttcaaaaga agaacgctca ctaagcgtga atcttagtca
     8581 atcgttgccc tagatagaaa tcgttaggat gtgaaaaaaa ggtggttcaa gaaaatattg
     8641 tcatagaaat gcagaatatt accaaagaat ttggaacatt caaggcaaat gacaacatca
     8701 atttacaagt aaaggcagga gaaattcatg cgttgcttgg agaaaacggt gctggcaaat
     8761 ctacattgat gaacgtgctt tccggattat tagagccgac atcagggaaa attttgatgc
     8821 gtgggaaaga agtaaagatc acaagtccga ccaaagccaa ccaattaggg attgggatgg
     8881 tccatcagca ctttatgctt gttgatgcct ttactgtaac agaaaacatc gtgttgggaa
     8941 gcgagcctag tcgcgcaggg atgcttgacc ataaaaaagc acgaaaagag atccaaaaag
     9001 tttctgaaca gtatggattg tcagtcaacc cagatgctta cgttcgtgat atttcagttg
     9061 gaatggaaca acgggtagaa attttaaaaa cactttaccg aggagcagat gtactgattt
     9121 ttgatgagcc gacagctgta ttgacccctc aagaaattga tgaattaatc gtgatcatga
     9181 aggaattagt caaagaaggc aagtcgatca ttttgattac gcataagtta gatgaaatca
     9241 aagcagtagc tgaccgctgt acagttatcc gccgtggaaa aggaatcggt acagtcaacg
     9301 ttaaagacgt aacctcacaa caattagccg atatgatggt tggaagaacg gtttcattca
     9361 aaacgatgaa aaaagaagcg aagcctcaag aagtcgtttt gtctattgaa aatctagtgg
     9421 tgaaagaaaa tcgtggatta gaagccgtga aaaacttgaa cttagaggtt cgtgctggcg
     9481 aagtacttgg tatcgctgga atcgatggaa acgggcagtc ggagttgatc caagctttga
     9541 ctggtttgcg aaaggcagaa agcggacata tcaagctaaa aggggaagac atcactaata
     9601 aaaaaccccg aaaaatcact gaacatggtg taggacacgt gccagaagac cgtcataaat
     9661 acgggttagt cctagatatg acattatctg aaaatatcgc actacaaacc tatcatcaaa
     9721 aaccttacag taaaaacggc atgctgaatt attcagtaat gaatgaacat gccagagaat
     9781 tgatcgaaga atatgatgtt cgaacaacga atgaacttgt tcccgcaaaa gctttatcag
     9841 gcggaaatca gcaaaaagca attatcgctc gtgaagtcga ccgagatcct gatctgttga
     9901 ttgttgcaaa tccaactcgt ggactggatg taggtgcgat cgaatttatt cataaacgtc
     9961 tgatcgaaca aagggacaaa tacaaagcag tgttactgat cagtttcgaa ttagaagaaa
    10021 ttttaaatgt ttcggatcgt attgctgtta tccatgaagg agaaattgtc ggtatcgttg
    10081 atccgaaaga aacatctgaa aatgaattag gtctattgat ggcgggctat accttagaag
    10141 aagcacgaaa agagttagaa aagggggctg gcgcacatga atgatcgcag cgaaaaattc
    10201 cgtaatttat tagtgcctgt actttcagtt gttttaggat tgatcttagg cgcgatattg
    10261 atggctgctt ttggttttca gcccatccaa ggttattctt ctatgctaga tgcagccctt
    10321 ggttcgcaaa gagggatagg tgaaacgtta aggcaagcaa cgccgttgat ttttacagca
    10381 ttaggttttt ctgtagctaa ctcagctggt tttttcaata ttgggctttc tggacaagca
    10441 ctttgcgggt ggatcgtcag tgtctgggtg gcacttgcgt ttccagatct gccaaaagtt
    10501 gttttgcttc cgttatgcgt gatcttaggt gccttagctg gtgcgatggc agcggctgtt
    10561 ccaggtttac ttcgagcatt ttttggaaca agtgaagtga tcgtaacaat catgatgaac
    10621 tatatcttat tatacgtaag cacatttgct ttacatgaag tgatgcctga aagctatcgc
    10681 tcaagtttgg actcttccaa tatgatcagt caaaatgcct cactgcggtt accatggtta
    10741 acacaagctt ttggcggctc tcgcgtaaac tcaggattat ttttagcaat catcgcgctt
    10801 attttcgttt ggctgctgat gaagaaaacg actttaggat ttgaaatccg ttctgttgga
    10861 ttgaatcctt ttgcttctga gtatgcagga atgagtagta aacgtacgat cgttttgtcg
    10921 atggtcattt ctggcgcttt ggcagggctt ggcggtgtgg ttgaaggatt aggaacgtat
    10981 caaaacttct ttgttcaaac gacttcgcta tctattggat ttgacggaat ggctgtttcc
    11041 ttgcttggtt ctggatcagc aatcggtatt cttttatcag cgatcttgtt cagtattttg
    11101 aagatcggtg gacttggcat gcagacagga gcaggtgttc cgtttgagat cgtcaatgta
    11161 tcgattgctt tgattatctt ctttgtcggg atcaacttcc tgattcgttt cgtcatggct
    11221 aaagtcttcc aagggaaaaa acaagaagag atcgttgcga caatagaatc gaaaccaacg
    11281 aatcaaaacc atgaaggggg cgaactataa tgtcgactat cgaattaatt gccttgatcc
    11341 ttacttctac actggtttat tcaacaccgc taattctaac gtcactaggc ggaacttttt
    11401 ctgaacgaag cgggatcgta aacgtagggc tagagggaat catggtcatg ggtgctttta
    11461 gttccatcgt tttcaacttg acgatgagtc catcacttgg ttctatgaca ccatggatcg
    11521 ctattttagt gggtggcgtc gtaggtatcc tattttctct gattcacgca gtagcaacag
    11581 tcagtttgcg tgctgaccat attatcagcg ggacagtaat taatctgatg gcacctgctt
    11641 taggtgtttt cttgatcaaa gcatggtatg gtaaaggtca aactgataac atcacgcaga
    11701 atctggggta tttttctttc ccaggattag cagatattcc ggtcattgga ccaattttct
    11761 ttaaaaatac attcttacct gcttattgtg ctattttgat tgctgtccta gcttgggtga
    11821 tcatcttcaa gacgaaattc ggcttgcgcc tccgttcagt tggtgaaaat cctcaagctg
    11881 ccgacacatt aggtatcaat gtatatgcta tgcgttattc aggcgtactg atttctggct
    11941 tgttaggcgg tatgggcggt gctgtttttg ctcagtcgat ttccggtaac ttttcagctg
    12001 gtacgatcgt tggacaaggg ttcatctcca tggctgctat gatctttggt aagtggaatc
    12061 ctttaggggc aatgggtgcc tcattgttct ttggttttgc tcaaagcttg agtatcattg
    12121 gcgcacaatt accagttatt tcttcgattc cgccagtatt gctgcaaatt gctccatatt
    12181 tgctgacaat cattgtgctg gttgttttct tagggaaagc ttctggtcca aaagcaaacg
    12241 ggaagaacta tatcaaatca aaataatctt ttagcgaata aaaagggtgg gttacgggaa
    12301 gtgtttttcg tctcgccctt tttgttttaa aggcaataaa aataaaaaga aagaaggaat
    12361 aatcatgttt aaacgcgtac atctgatcgt catggattca gtaggaattg gagaagcacc
    12421 agatgccgat aagttcggtg atgttggttc tgatacatta ggacacattg cgaaagaagc
    12481 aggattgaac gttccacatt tagagcagct tggtttagga acgatccgtc ctcttgaagg
    12541 tgtggaatca gtgaaagatc atcaaggcta tgcgacgaaa ttagaagaag tttctgtagg
    12601 gaaagatacg atgacaggcc actgggaaat catgggattg aatatcaaaa ctccatttcg
    12661 tgtgtttcct aatggattcc ctgatgatct gatcaaacaa atcgaagaat tttctggccg
    12721 taaagtcgta tgtaacaaac cttatagcgg aacagctgtt attgacgatt acggtgaaca
    12781 ccaaatgaaa acaggcgatt taattgtata tacttctgcc gatcctgtcc ttcagatcgc
    12841 ggcacatgaa gaaatcattc ctttagaaga attatatcgg atttgccaat tcgttcgtga
    12901 tataacaaaa gatgatccgt atatgattgg ccgaatcatt gcacgtccgt acgtgggtga
    12961 accaggagac ttcacacgaa caagcaatcg ccatgattat gcgttgaatc cattcggaca
    13021 cacagtcctt gattctttga aagaagcagg aaaggacgtg attgctgttg gaaagatcaa
    13081 cgatattttc aacggacaag gaatcactga atctgtccgc acgaaaagca atatggatgg
    13141 cgttgaccag ctgctgaaag ttatgaaaaa cgatttttca ggaatcagct ttaccaattt
    13201 agtagatttt gatgcattat acggtcatcg tcgggatgta gtcggctatg cgcatgcgat
    13261 tgaagaattt gacttacgaa ttccagaatt gcttgaagcg atggaagaag acgacttgct
    13321 aatgattaca gccgatcacg gaaacgatcc gacgtttact ggtaccgatc atacgcgaga
    13381 atatgtaccg ttattggttt acagtaaaaa aatgaaagaa caaggggcat tgcctcaagg
    13441 atattattca gatatttcag caacgattgc tgagaacttt agtgtttctt cgactgaaaa
    13501 tggcgaaagc ttcttgaaat tattaaaata atctttttaa ataggagaaa gcaaatgacc
    13561 aagttaagcg agatgttaca agaaacgacc cagtttatcc ttgataaagg agtaaaagaa
    13621 attgattttg gtttgattct aggttcagga ttaggtgaat tagcagatga aatcgaagat
    13681 gctgtaatga tttcttatga tgagatcccg ttctttcctg tttcgacagt agttgggcat
    13741 gcaggaaagc tagtttatgg gtctctggca ggcaagaaag tgttagccat gcaagggaga
    13801 ttccactact atgaaggtca ttccatgcaa acagtgacct atccagtacg tgtgatggcc
    13861 ggactagggg cccattcagt cattgtgact aatgcatgtg gtggtgtcaa cgaatcattt
    13921 gtaccaggag atttgatgct gattaccgat catatcaatt ttactggtga aaatcctttg
    13981 atcggtccga atgaagatgc aatgggccct agatttccag atatgagtca agcttatacg
    14041 cctgactatc aagcaacagc aaaagcagca gcagaaaaac taggtttgga tcttaaagaa
    14101 ggcgtatata tgggctattc tggaccaact tatgaaacgc ctgcggagat ccgaatgtct
    14161 cggacaatag gagccgatgc agtagggatg tcgactgttc cagaagtcat cgtagcagct
    14221 cacagcggat taaaagtgtt aggaatctct tgtattacca acttagcagc aggtatgcaa
    14281 gcgaatctga gccatgaaga agttgtagaa acaactcaga gagtcaaaca atcttttaaa
    14341 gcattggtta aagaaacatt gacattattg taataggagg aacaataaaa tgagtgtgca
    14401 tattgaagcg aaagaaggcg agatcgccga taagatttta cttccgggag atcctttgcg
    14461 agctaaatat attgcggaga cttttttgga agatccagtt tgttacaatc aggtacgcgg
    14521 tatgttaggc tttaccggca aatataaagg agaacgtatt tctgttcaag gaacaggaat
    14581 gggaatgcca tcagccacca tctatgccca tgaattgatc cagtcgtatg gtgtaaagaa
    14641 attgattcga gtaggtacat gcggtgcatt gtcaaaagac gtccatgttc gtgatttagt
    14701 actagcacaa ggtgcagcga ccagttcttc gatgatcgaa aaaaatttcc aagcctttca
    14761 ttttcctcca atcagtgatt tcaatctatt actgaaagca tatgagatag ctaaagaaaa
    14821 gggctatacg gttcatgtag gaaatgttct ttcggaagat tctttctaca aagatgattt
    14881 gacagagacg ttccaattag ctgaacttgg cgttttagga gtggaaatgg aagcagcggc
    14941 tctttattac ttaggcgcga aataccatgt gcagacatta agtttgatga ccgttagcga
    15001 ccatttgatc accggtgaag aaacaacagc tgcagaacgt caatctacgt tcaatgaaat
    15061 gatcgaagta ggattggaaa cagcgatagc agaa
//
LOCUS       DAKCAA010000059        14921 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000059 DAKCAA010000000
VERSION     DAKCAA010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14921
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.059"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(491..895)
                     /locus_tag="OUE31_002100"
     CDS             complement(491..895)
                     /locus_tag="OUE31_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0223085.1"
                     /translation="MTNEIILMSHGLMAEEILNSAKMILGNQINYPVVSMTQNDGIEG
                     TINKLNKILEETSDIRNIIILVDLMGGTPANVAMMKASMDKRIQVVTGMNLGMVLESY
                     FKINEEKLAEHLIEIGKSSIKIPEIQMDGGEE"
     gene            complement(910..1392)
                     /locus_tag="OUE31_002101"
     CDS             complement(910..1392)
                     /locus_tag="OUE31_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0223086.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDTVANND
                     IQKQVLRMAVPAGISSSIITEEKAITNIKNGKYEGQNVLLIVKSPVDLLSFIENDLQI
                     DRINVGNMSNRKGTTVLRPNISVTNEERNAFEKLLNLGVEITTIMTPDDKKTYLKDIL
                     "
     gene            complement(1412..2224)
                     /locus_tag="OUE31_002102"
     CDS             complement(1412..2224)
                     /locus_tag="OUE31_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCU0223087.1"
                     /translation="MNSLETTKLGVNSKIKKSVLWRWFFTSSVSSNYEKMQALAYCYA
                     VLPFLKVTYKNKPEALQKAVLNHLQFFNTNPWVAPYILGINIAMEENSDENTEEAVTS
                     IKTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPVGIILWIAVSVALKMISIPL
                     FRIGYTSGTKLITTIEKSLKLLTESTSILGLMVVGALIPSVVKTNVVLDFKQGDFSMR
                     GQEILDQIMPGLLPALLVGLVYWSLKKNVKPIYLILGVMVLSIVLATLGILK"
     gene            complement(2217..3002)
                     /locus_tag="OUE31_002103"
     CDS             complement(2217..3002)
                     /locus_tag="OUE31_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCU0223088.1"
                     /translation="MEISVIQLGLIVLYGFFINFEKNSTMFGTYQPVTAGFVTGLILG
                     DIKTGLFIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTGQESSVGISIGIPV
                     ALLMVQLDIIRNTIGIWMVHKAEAGVKRGDYSMISKMQMFGVFLTAATTGIPVALAVI
                     FGPSLINTILAHTPEWLTNGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVMSVY
                     LKMPLLGVALIGAAIALIIYKKNSQNVINNTVVNTIGGMDEDE"
     gene            complement(3002..5077)
                     /locus_tag="OUE31_002104"
     CDS             complement(3002..5077)
                     /locus_tag="OUE31_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HCU0223089.1"
                     /translation="MKEVINIESNYFSRKFDDELLIIEAWGENAIRIRSFVDMNYEDR
                     QNSLIDKPNSLNKVIINQYENKTELINGKIRAVLDHRDRLTFYNEKNDVLLKEYIRLR
                     AVKHDDGGEDAGSVEVTKDFNSTLKLKSREYRSNMDGKFQVTTRFESDPKEKIFGMGQ
                     YQHSYLDLKNTVLELAQRNSQVSIPFYISSLGYGFLWNNPGIGEVSFAKNITRWKMYS
                     SDYIDYVIISGNEPKEILRNYSNLTGKVPKMPDSLLGLWQSKLRYRSPEEVMDVVEKY
                     HKRGIKLSTIAIDYFHWPKQGEYCFDEEYWPNPEKFLKTLKTDYGVEPIISIWPTVQT
                     DAENYEKYLENGYLVKVNRGVRLTMQIQGNTIFIDMTNSEARKYVWSLIKKNYVDKGI
                     NYFWLDVAEPGYSVYDFDNYRYKKGTDLYSGNLYPIDYLSMIYEELSNEQPVITLVRG
                     GWAGAQRFGALLWSGDIDSSFEAFRNQVNTGLNVGLAGIPWWTTDIGGFHGGNPEDPE
                     FRELLIRWFQYATFSPILRMHGDRLPHSKPLSDHGGGSMVTGAPNEIWSYGIEVEQIL
                     TKYIKIREALKPYISTLMDKAHRFGDPIMRTLFYEYPSDNNTWAVEDTYLFGDTFLIA
                     PIVNYKETVREVYLPINENWTNIWTGEEYDGGQTLDVEADISMIPVFIKTNQKDKFSK
                     LLSIIKEEI"
     gene            5385..6551
                     /locus_tag="OUE31_002105"
     CDS             5385..6551
                     /locus_tag="OUE31_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HCU0223090.1"
                     /translation="MISSKYTIREQNEAKILNQIIRHKEISRAELSKITSLNKASVSS
                     IINKLIDDSLVIENRIGEATNRGRKPIMLTFNGVSSGLAIAIDLGYNYIDGMVASLDG
                     KEIARIQLTDTYVSKDNIQMLIRKIIKKLTDNLPYTRHGIIGMTIAVQGQVLNNKVLS
                     TTYNGLEEIDLVKLLNQEYSFPVFLQNEANLSALGEYTFSSDIENLVSISLHSGIGVG
                     VVKNGKLDIGNKGYAGQLGHTILFPNGRKCECGNYGCLEKYCSTQVIYQEISKEKKLD
                     KINSDIVEYLYSNKDQKVVEMIELYAYYLSIGINNIVMLYAPELVIFNSPLTKKIPNI
                     INIIKNFLNNQYTKEIHIINSPIEWNPVLSGAISFSIQKFLNIEKLKLSSYAKN"
     gene            complement(7143..7622)
                     /locus_tag="OUE31_002106"
     CDS             complement(7143..7622)
                     /locus_tag="OUE31_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCU0223091.1"
                     /translation="MIKFLRKKKQVELFSPCSGKVIPISEVNDPVFSQKLLGEGFAVI
                     PEEQTIYAPLAGQVTTIFPTKHAISIKSNSGIDYLIHIGIDTVELEGKPFSILVDEKE
                     YITPENPLVKVDFKQLELAKKDSSVIICFTESSQIDNLDLYTGRVLHGVLCGYLNLS"
     gene            complement(7634..9136)
                     /locus_tag="OUE31_002107"
     CDS             complement(7634..9136)
                     /locus_tag="OUE31_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCU0223092.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPIL
                     AQPWLHTILSIMSYAGNAIFANLALIFAIGIAVGLANGDKGTAGLAGGVSYLVYTATI
                     SGFLELFSVKDATLDTGVVGSIAIGGIVAFLHNRYRKIELPQFLGFFGGSRFIPIISS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEHIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTESVAGITVSGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGLAWAIIYFIVFTFFL
                     KKFKVAIPGMIEEKEVVSEINLNKNTSLHEESLMIIKALGCEENIESVEACATRLRVA
                     VKNGQNVDKQAIKQLGATAVFEVKGGIQAVFGGKADLLSQEINQILKRDN"
     gene            complement(9129..9836)
                     /locus_tag="OUE31_002108"
     CDS             complement(9129..9836)
                     /locus_tag="OUE31_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCU0223093.1"
                     /translation="MKKQIFLDAISGGLIVSCQALPGEPFYKEEGGLMSYFALAAERA
                     GAVGIRANSVRDILEIKEKVSLPMIGIIKRDYPPEEPFITATMREVDELVATGVEVIA
                     LDCTLRKRHDNLSINTFITQIKEKYPEQLLMADISTFEEGKNAYEAGVDFVGTTLCGY
                     TNESRKQEGPAIDLMKQLVQAEICVIAEGKIHTPEQAKKIRELGVSGIVVGGAITRPQ
                     EIAERFVNALKEEEKNV"
     gene            9999..10817
                     /locus_tag="OUE31_002109"
     CDS             9999..10817
                     /locus_tag="OUE31_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCU0223094.1"
                     /translation="MNYIYLIKEHYPLLTKSEKKVADLILDSGKAIIYSTMSDIKEKT
                     TVGDATIIRFCQKLGFSGFSDLKIEIAKEDFSKKKEYPSSEKYYDIIATHLTEALYST
                     AHLLDEKKLDKAIQLISQAKNLYIFGVGSSGNTSLDLESMFLRVGVQAKAVLDPHFQA
                     QVASLMEEDDVIIAFSLSGKTKDTFDSVEIAKKNGAKILAITNYLHSPIGQTADVVLQ
                     TAIEEFLNGGSLAGKISQLYLCDLLVQGYEQKNNINAVELRERVLRSILDKSLD"
     gene            complement(11178..11804)
                     /locus_tag="OUE31_002110"
     CDS             complement(11178..11804)
                     /locus_tag="OUE31_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCU0223095.1"
                     /translation="MTISNKNSMREEIIIIAIKHFSKFGYEKTRLLDIANEAKTSTTT
                     VYSFFKTKHDLYEAAVEYDLNIINLELEKIVKESSTLDEYIINIVERVRLNSEKKQLF
                     LNFFMLISTNSGQIKKIDIIEEFERKKFSFYFKFIESPKVKDRYTLLFIDNLITIYIY
                     SYFNVFYRKKLLLYLSLYQQDKQSIEFEEDLLKHLKILIRTRLFIDKN"
     gene            complement(11811..12455)
                     /locus_tag="OUE31_002111"
     CDS             complement(11811..12455)
                     /locus_tag="OUE31_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCU0223096.1"
                     /translation="MYKTANELFNRLKSEKKELILNYILEEFGRVGYESASVRKIADK
                     ADLSAGSLYQYFNNKEGMLRVAIEHVFVILDEYINNINNAPLKLENRLEVMFETILEL
                     GRKHPELIVFYNKIPGDEQMTSEWVKQFYNNTSFFKVYWHTVNELQDEKEISDKIDPV
                     VYTFIIDTMMLSGELLQNTQYQEIKAKIFLEDSIKSSLILKENVIETLTVLARG"
     gene            complement(12864..13999)
                     /locus_tag="OUE31_002112"
     CDS             complement(join(12864..13720,13720..13999))
                     /locus_tag="OUE31_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611996.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCU0223097.1"
                     /translation="MSERKPRRTFTKEFKNQMVQLYASGKKRTDIIREYDLTPSTFDK
                     WVKQANTSGSFKEKDNLTPEQKELIQLRKQNKQLLIENDILKQAALIFGPKRQVIDAN
                     KHKYSISAMCKVLGIARATYYYREKETTQGAVEAKLEEAVEEVFQQNRRAYGSRRIKK
                     RLDKKNLILSRRKIRRIMKRRGLKSSYTKPKYRVHSCQSNQKKIANHLDRKFTQTKAL
                     SAVVTDLTYVRVGTNWAYICLMIDLFNREIIGHSCGNKKDAQLVKRAIQSIPYSLQEI
                     ELFHTDRGKEFDNELIDLILETFGIQRSLSKPGCPYDNAVSEATYKAFKTEFVSQYQF
                     ETMAHLELECFDYVNWWNHHRIHSSLGYKTPIEVRYAEVGVANP"
BASE COUNT         5040 a         2682 c         1981 g         5218 t
ORIGIN      
        1 tttgattgga caacattcat atatatatca aaaaaacttt aacacaacta tataatattt
       61 gcatatagat catatcccac cgctgttaag attgttacat ctagaattag tacctactct
      121 ggcactaatt tcctaaccgt ctcattgaaa ataccactta tacttgaaag catcttcaat
      181 cttagattgt cctccaaata gtacactcga accattattg ctttactatt taactatttg
      241 gtttttatag cagttcaagc actagctata ccgtgctatt ccaaaaagag cccttttaac
      301 attcctctat ttcgctagta ttaattattt aagattataa tgaaaaaaac atatttctta
      361 ctatggcttc gtatctaatt ttgatattat gtagaaaacg aatcatatta atatcgaaaa
      421 tagatttcct tttgttttga tttaaacttt ttcaattgag attaacagaa ctattcttcc
      481 ttcattataa ttactcttct ccaccatcca tctgtatctc aggtatttta atactacttt
      541 tacctatttc tattaaatgc tcagcaagtt tttcttcatt aattttaaag tatgattcta
      601 ataccatccc tagattcatt ccagttacta cttgaattct tttatccata cttgctttca
      661 tcatagctac atttgcaggt gttcctccca ttaggtctac taatataata atatttcgta
      721 tgtcacttgt ttcttccagt attttattca atttatttat tgttccttca ataccgtcat
      781 tttgtgtcat agaaactacc ggataattaa tctggtttcc aagtatcatt ttagctgaat
      841 ttaatatttc ctcagccatt aaaccatgac tcattaaaat tatttcatta gtcatcgcac
      901 ttattcccct tataaaatat cttttaagta agttttttta tcgtctggtg tcataattgt
      961 agtaatttca acaccaagat ttaatagctt ctcgaaggca tttctttctt cattagtaac
     1021 gctaatatta ggacgtaaaa ccgttgttcc ttttcgatta gacatgttgc caacgttaat
     1081 cctatctatc tgtaaatcat tttcgataaa cgataataag tctactgggg atttgactat
     1141 taaaagcaca ttttgccctt catattttcc atttttaata ttggtaatcg ctttctcctc
     1201 agttataatt gaagaactga ttcctgcagg gactgccatc cttagcacct gtttttgtat
     1261 atcattattt gcaacagtat catttacaac catcaaacga gtcacaccta atttattact
     1321 ccacattgta gctacttgac catgaattaa tcgatcgtca attctaatat tttttatacc
     1381 cttcatttcc acaaaaattt cctcctatca tttattttaa aatgcctaga gtagctaaaa
     1441 caatagacag aaccatcaca ccaagaatta aataaatagg ttttacattt tttttcaaag
     1501 accagtaaac taaaccaact aaaagtgcag gtaataatcc tggcattatt tgatctagta
     1561 tttcttgccc tctcatagaa aaatcacctt gtttaaaatc taagacgaca tttgttttaa
     1621 caacagatgg tattaatgct ccaacaacca ttaatcctaa aattgaagtc gattcagtta
     1681 aaagttttaa acttttttca atagtagtaa ttaatttcgt acctgaagta tagcctatgc
     1741 gaaataatgg tatacttatc atctttaaag ctacacttac agcaatccat aaaataattc
     1801 ctactggact accatcaatt gccatatttg ctgcaatagc cccaaatata gtccatggaa
     1861 taactacaaa tagactatca cctaatccag ctactggccc cataagtcct gtcttaatcg
     1921 atgtcactgc ttcttcagta ttttcatctg aattttcttc catagctata ttaataccta
     1981 aaatatacgg tgcaacccaa ggatttgtat tgaaaaattg taaatgattt agtactgctt
     2041 tttgtaacgc ttctggtttg tttttataag taacttttaa gaatggtaat acagcgtaac
     2101 aatatgctag agcttgcatc ttttcataat ttgaagaaac tgagcttgta aaaaaccatc
     2161 tccataatac actcttttta attttggaat taacaccaag ttttgtcgtc tccaagctat
     2221 tcatcctcat ccatacctcc tattgtatta acaacggtat tattaattac attctgacta
     2281 ttttttttat aaataattaa agctatagca gcgcctatta atgctactcc taataatggc
     2341 atttttaagt aaacagacat tacaaaaccg ataacaagat aactgaaata ttcttttgca
     2401 ggtaagtatc gaagcaataa accaatacca acagctggta ataatccccc agcaactgtt
     2461 aacccatttg ttaaccattc aggagtatga gcaagaatag tattaattaa agatggtcca
     2521 aaaattactg ccaacgcaac cggtatgccc gttgttgccg ccgttaagaa tactccaaac
     2581 atttgcatct tggagatcat actataatct cctcgcttta cacctgcttc tgctttatga
     2641 accatccaaa taccaattgt atttctaata atatctaatt gaaccattaa tagtgctact
     2701 ggtataccaa tagaaatccc taccgaagat tcctgaccag ttgttatggt gataaaagtt
     2761 gcgacaatac ttgcagtttg atagtctggt atagaagctc ctccaaaatt actaattcct
     2821 aaagacaata attgtaaggt tcccccaata aaaagcccag tttttatatc tccaagtatt
     2881 aaaccagtta caaatcccgc tgttacaggt tggtaggttc cgaacattgt tgaattcttc
     2941 tcaaaattaa taaaaaaacc atataacaca attaaaccaa gttgaataac acttatctcc
     3001 attagatctc ctccttaatt atacttaata gttttgaaaa tttatctttt tgatttgtct
     3061 ttataaaaac aggtatcata ctaatatctg cttcaacatc caacgtttgt ccgccatcat
     3121 attcttcacc tgtccatata ttggtccagt tttcatttat tggtaagtaa acttctctta
     3181 ctgtttcctt ataatttaca atcggtgcaa ttaggaacgt atctccaaat aagtaagtat
     3241 cttctacagc ccaagtatta ttatctgaag gatattcata aaatagcgtc ctcatgatcg
     3301 gatctccgaa tctatgagct ttatccatca aagtactgat atacggtttc aacgcttcac
     3361 gtatttttat atacttagtt aatatctgct caacttctat accgtatgac catatttcat
     3421 ttggtgcacc agtaaccatc gaacctccac catgatccga taagggttta ctatggggta
     3481 atcggtcacc gtgcattctt aaaattggtg aaaaagtagc atattgaaac caacgaatta
     3541 gcaattctct aaactccgga tcttctggat ttccgccatg aaacccacct atgtcagttg
     3601 tccaccaggg aatccctgct aaacctacat ttagtccagt attaacttga tttctaaatg
     3661 cttcaaaact agaatcaata tctccagacc acaataatgc accgaatctt tgtgctccag
     3721 cccatcctcc tctaacaaga gtaattacag gctgttcatt acttaattct tcataaatca
     3781 ttgaaagata atcgattgga tataaattac cactatataa atcagtcccc tttttataac
     3841 gataattatc aaagtcataa acggaatatc ctggctcagc tacatctaac cagaaataat
     3901 taatcccttt atcaacataa ttctttttaa ttagactcca aacatatttc cgagcttcac
     3961 tatttgtcat atcaataaaa atagtgtttc cttgaatttg catggttaat cgaactccac
     4021 gattaacttt tactagataa ccattttcta aatatttttc ataattttct gcatcagttt
     4081 gtactgtagg ccaaattgag attattggtt ccactccgta atcagttttc aaagtcttta
     4141 aaaatttttc tggattaggc cagtattcct catcaaaaca atattctcct tgctttggcc
     4201 agtgaaaata atcaatagcg atagttgaaa gctttattcc acgtttatga tacttttcta
     4261 ctacatccat cacttcctct ggtgatctat atcgtaattt gctctgccat aatcctaata
     4321 aactatctgg cattttaggg acttttccag ttagattact atagtttcta agtatttcct
     4381 ttggttcatt tcctgaaatt attacataat cgatataatc agaagaatac attttccatc
     4441 gagttatatt tttagcaaaa gaaacttctc caataccagg attattccat aaaaaaccgt
     4501 atccaagact agatatatag aatggaattg acacctgtga gtttctttgc gctaattcta
     4561 aaacagtgtt cttcaaatca agataagaat gttgatattg acccattccg aatatttttt
     4621 cttttggatc tgattcaaat ctagtagtta cttgaaattt accatccata ttggaacgat
     4681 attctcttga ctttaatttc aatgtagaat taaaatcctt tgtaacttca actgaaccag
     4741 catcttcacc accatcatca tgtttaacag ctcttaatct aatatattct tttagtaaga
     4801 catcgttttt ttcattataa aaagttaaac gatcacgatg atctagtacc gctcttattt
     4861 tcccgttaat taattctgtt ttattttcat attgatttat tatcacttta tttagggaat
     4921 taggcttatc aattaaggag ttttgtcgat cttcatagtt catgtctaca aatgaacgta
     4981 ttctaatagc attttccccc catgcttcaa taatcagtaa ttcatcatca aattttcttg
     5041 aaaaataatt tgattcaatg tttatcactt ctttcatccc actttccttt tcttcttaat
     5101 tagttaactc ttattacaac actagcaatt gtaatcgcat acatatacat atcaatttaa
     5161 tttaagtatt ttgactagaa ttctgctttt taatttgttt tctcgataaa ctaattatca
     5221 aaaaaaaaac taataacaaa aaacacttaa ttacttgaac taaaattgtt tgtacgttaa
     5281 actaattaat aaataaaata taaaataagc tatttaaaat gtcaactgta aacgctatat
     5341 tttttttgca taggctattt tatttttaaa ttgaggagaa attaatgatt tcaagtaaat
     5401 atacaattag agaacaaaac gaggcaaaaa tacttaatca aataattaga cataaagaaa
     5461 tatctagagc tgaattgagt aaaataacct ctttaaacaa agcatctgta tcttctatta
     5521 tcaataaatt gatcgatgac tcgcttgtaa ttgaaaatag aattggagaa gcaacaaatc
     5581 gtggccgaaa acccattatg ttaactttta atggagtatc ttcgggctta gcaattgcaa
     5641 ttgatctagg atataattac attgatggaa tggtagcttc attagatgga aaagaaattg
     5701 caagaataca gcttactgat acttatgtta gtaaagacaa catacaaatg ttaattcgta
     5761 aaattataaa aaaactcacc gataatcttc cttatacgcg acatggaata atcggtatga
     5821 caattgctgt tcaaggacaa gttctaaata ataaagtact tagtacaact tataacggtc
     5881 ttgaggaaat tgatctagta aaattattaa atcaagagta tagctttcct gtttttttac
     5941 aaaatgaggc aaacttatct gcattaggtg aatatacttt ttcttctgat atcgagaatt
     6001 tagtatcaat tagtcttcat agtggaatag gcgttggagt agtaaaaaat ggtaaacttg
     6061 acattggtaa taaaggatat gctggtcagt tgggacatac aattctattt ccaaatggca
     6121 gaaaatgtga atgtggtaat tatggttgtt tagaaaaata ttgctctact caagtaattt
     6181 accaagagat ttccaaagaa aaaaaactag ataaaattaa ttcggatata gtggaatatc
     6241 tttatagcaa caaggatcaa aaggttgtag agatgattga actatatgca tactatttat
     6301 cgataggaat taacaatata gttatgctct atgctcctga gttagtgatt tttaacagtc
     6361 ctttaacaaa aaaaattccg aacataatta atataatcaa aaattttttg aataatcaat
     6421 atacaaaaga aattcatatc attaacagtc ctatagagtg gaatcctgtt cttagtggag
     6481 caatttcgtt ttcaattcaa aaatttttaa atattgaaaa gttgaaactc agctcttatg
     6541 caaaaaatta atttaattta gtggaaacta gtatgtgaaa tggagaaatt ttaacatact
     6601 agacggctca ccagtactct ctccttaaaa agagcttttt atatagttat gaatttctca
     6661 ccgctctacc tctttttcaa gagataaaaa aattaataca atgcttatta cttaaactat
     6721 ttctaactca ataatctatc aaatattctc aatttttttc aattgtcttt ttgtttaatc
     6781 aaagcatgct tgcttattat ccatttggcc tatactttag ggtaaaattt tacaatttca
     6841 tctaaattat atactaaact tttatcgcta ttaaaagtaa aaacagcttc gcccacgtat
     6901 agaaacgtat atctttttgt ttctacacgt gggcgagctg actaaaatca tataatcaaa
     6961 aacttaataa aacgaggttc actccaatca tatttcattt ttcaaaacta tcacattaat
     7021 ctcttgtcaa tcaaaattat tatacattga gaaagttaca acttatatac tacttcttta
     7081 aactctaaaa cttcaccaat gagtttctaa taattagatc ttattaatct aactattaat
     7141 cattatgata aatttaaata cccacaaaga acaccatgta aaactcttcc tgtatataaa
     7201 tcgagattat caatttgact agattcagta aaacaaatga ttactgatga gtctttttta
     7261 gccaattcaa gctgtttaaa atcaacctta actagtggat tttcaggtgt tatatattct
     7321 ttttcatcaa caagaattga aaaaggtttt ccttctaatt ctactgtatc tatcccaata
     7381 tgaatcaaat aatcaattcc tgaattactc tttatactaa tagcatgttt tgttggaaag
     7441 atagttgtga cctgaccagc taaaggagca taaattgtct gctcttctgg aataacagca
     7501 aaaccttccc ctaataattt ttgtgaaaaa actggatcat ttacttctga tataggaata
     7561 acttttcccg aacatggaga aaatagttcc acttgttttt tctttcttaa aaacttaatc
     7621 atataaattc ctcctaatta tctcttttca aaatttgatt gatttcttga ctaagtaaat
     7681 cagcttttcc tccaaaaact gcttgaatcc caccttttac ctcaaaaact gcagtagcac
     7741 ctaattgttt tatagcttgt ttgtcaacat tttgtccatt cttcacagca acacgcaagc
     7801 gagttgcaca ggcttcaaca gattcaatat tctcttcaca gccaagtgct tttataatca
     7861 ttaaagattc ttcatgcaaa gaagtatttt tattcaagtt aatttcagag actacctctt
     7921 tttcttctat cataccaggg atcgctactt tgaatttttt taaaaagaaa gtaaaaacga
     7981 taaagtaaat aatagcccaa gcaagtccaa aaggaatcaa tttaagccag ttagttttgt
     8041 catttccttg aagtacacca aataatagaa aatcaattag tccacctgaa aaagaatttc
     8101 ctactcgaat attcaggata tccgcaaaat aaaaagatag gccgtctaaa aatgcatgga
     8161 tgacataaag ccatggagcc acaaacagaa acatatattc tacaggctca gtgattcctg
     8221 ttaaaaacga agttaatgca ccgctgaaat aaagaccgcc atttttctta cggttttttt
     8281 taggaattgc acgatacatc gcataacaag cagcaggaag gccaaacatc atcgtggcaa
     8341 atcttccagc aaaaaaacga gtcccataag taaataagcc tgtgtgattc ggatcagcta
     8401 attgagcaaa gaaaatattt tgtgccccag aaactgtaat tcccgctaca ctctcagttc
     8461 cccctaacga agtgtaccag aaaagtggat aaattgtatg atgaagacca acagcaccag
     8521 ttaaacgaag taaaaatcca taaagaaatg ttcctagact ccccatttga gcaatatgct
     8581 ctccagcaac aactaatcca ttctgaatcg gtggccaaat tagataaaag aaggaaccaa
     8641 taataattgc agccaaacta gaaataattg gaataaaacg tgaaccacca aagaatccta
     8701 aaaactgcgg taattctatt tttctatagc gattgtgtaa aaatgcgaca attccgccaa
     8761 tggcaattga acctacaact ccagtatcaa gagttgcatc tttgacagaa aataattcaa
     8821 gaaaaccact aattgttgct gtataaacta agtaagaaac accaccagct aaaccagcag
     8881 ttcctttgtc accatttgca agccccactg cgataccaat cgcaaatatc aatgctaaat
     8941 tagcaaaaat ggcgttacca gcataactca tgatactcaa aatcgtatga agccacggtt
     9001 gagctaatat gggataagca tttatggcgc tttcatttgt cagtgcaccg ccaagaccta
     9061 aaagtaaacc agcaacaggt aaaatagcga tcggcaacat aaatgcccga cctagttgtg
     9121 aaaatttttt aaacattttt ctcttcctcc ttcaatgcat tgacgaaacg ttctgcaatt
     9181 tcttgtggac gagtgatcgc gccaccaact acgattccag aaacacctaa ttccctaatt
     9241 ttttttgcct gctctggggt atggattttt ccttctgcaa taacacaaat ttctgcttga
     9301 acgagctgtt tcatcaagtc aatcgctggc ccttcttgct ttctactttc attagtatat
     9361 ccgcataacg tggttccgac aaaatcaacg ccagcttcat aggcattttt accttcttca
     9421 aaggtagaga tgtctgccat taataattgt tcaggatact tttctttgat ctgagtaatg
     9481 aaagtgttga tagacaaatt atcatggcgt ttgcgcagcg tacaatctag cgcaataact
     9541 tctacaccag tagcaactaa ttcatcgacc tcacgcatcg ttgcggtaat aaatggttct
     9601 tcaggaggat aatctcgctt aattatccca atcataggta gagaaacttt ttctttaatc
     9661 tctaaaatat ctcgaacaga atttgctcgg ataccaactg caccagctct ttcagcagct
     9721 agagcaaaat aggacataag acctccttct tctttataaa atggttcacc aggtaatgcc
     9781 tgacaagaaa caatcagtcc acctgaaatt gcatctaaaa atatttgttt cttcattctc
     9841 ctaaacactc cactttaaat taattttcgg ataataactc caaataaaat atagcacgcg
     9901 ctttcattga tgtaaagtat aaaaatggat aaatttggag atttttttat ctttttggag
     9961 tataatggag taaaattttt tactgtaaag gagttcatat gaattacatc tatttaatta
    10021 aagagcatta tcctttattg actaaatctg aaaaaaaagt agctgattta atcttagatt
    10081 ctgggaaagc aattatttat agtacaatga gcgatatcaa agaaaaaacc acagttgggg
    10141 atgcaacgat tattcgtttt tgccaaaaat taggattttc tggtttctct gatttgaaga
    10201 tcgaaattgc aaaagaagat ttcagtaaaa aaaaagaata tccgtcaagc gagaaatatt
    10261 acgatataat tgctactcat ctaactgagg cgctctattc tacagcacat ttactagatg
    10321 aaaaaaaact agataaggca atccaactca tcagtcaagc aaaaaatctt tatatatttg
    10381 gggtgggttc tagtggaaat acaagccttg atttagaaag tatgttctta cgagtaggag
    10441 ttcaagcaaa agctgttctg gatcctcatt ttcaagctca agtagcttct ttgatggaag
    10501 aagacgatgt gattattgct ttttcattat ccggaaaaac aaaagatacc tttgattctg
    10561 tagaaattgc aaaaaaaaat ggtgcaaaga tcttagcaat taccaattac cttcattctc
    10621 caataggaca gacagcagat gttgttttac aaacagcaat cgaagaattt ttaaatggtg
    10681 gttctttggc agggaaaatc tctcaattgt acctttgtga tttacttgta caaggttatg
    10741 aacagaaaaa caatattaat gcagtggaat tacgtgaaag agtattacgc tctatcttag
    10801 ataaaagctt agattaaata gagtattaat tgaagcaatt tatatttagg tgaaatatca
    10861 attaattagt gggactcaca atttgcacaa ataactttca tcttaccttt agatgaagtg
    10921 ttagaaagaa aagtatcaac catcaatact ttgaaaaaat tctttttata ggaatatgat
    10981 gaacagcttt caatatacaa taatcattat caaagataac tgacaacttt tagcaataaa
    11041 atacaaaaca cttttttagt cagtatctaa atataacaaa tctatttcat aaagcaaaaa
    11101 agcggctaga caaaagagat gtctaaccac ttacatttat catctatata attcaatgaa
    11161 cagagaaaaa aaggacatca gtttttatca ataaaaagtc ttgttcttat caatattttc
    11221 agatgtttta gcagatcctc ttcaaattct atagattgtt tatcttgttg atataaagat
    11281 agataaagca ataatttttt tcgataaaat acattaaaat atgaatagat ataaatagta
    11341 attaaattat ctataaacaa taatgtatag cgatctttta ccttagggga ttctataaat
    11401 ttaaaataga aagaaaattt ttttctttca aattcttcta taatatctat tttttttatt
    11461 tggccagaat tggtcgaaat aagcataaaa aaattcaaaa acaattgttt cttttcagaa
    11521 tttaatcgta ctctttcaac tatatttata atatattcat cgagtgtaga actttcctta
    11581 acaatttttt caagttcaag gtttattata tttaaatcat actccactgc agcttcatac
    11641 agatcatgtt ttgttttaaa aaaactatat acagtagtag tactagtttt agcttcatta
    11701 gcaatatcta aaagtcttgt tttctcataa ccaaatttag aaaaatgctt tatagcaata
    11761 attataattt cttctcgcat gctattctta ttacttattg tcatagactc ttaccccctt
    11821 gcaagtacag ttagcgtctc gataacattt tcttttaata ttaatgaact ttttattgag
    11881 tcttctagaa aaattttggc ttttatttct tgatattgcg tattttgaag taattctccg
    11941 gataacatca tcgtatcaat aatgaacgtg tagacaactg gatcaatttt atcacttatt
    12001 tctttttcat cttgtaattc atttacggta tgccaatata ctttgaaaaa actagtgtta
    12061 ttgtaaaatt gtttaaccca ctcgcttgtc atttgttcgt caccaggaat tttattataa
    12121 aaaacaatca attcaggatg ttttcttcct aattctaaga ttgtttcgaa cattacttct
    12181 aaacgatttt ctaattttaa aggagcattg tttatattat taatatattc atctaaaata
    12241 acaaaaacgt gttctattgc tactcttagc attccttctt tattgttaaa gtactgatat
    12301 aatgatcctg cacttaaatc tgccttatca gcaatcttac gaactgaagc agattcataa
    12361 ccaactcttc caaattcttc taagatatag tttaaaatga gttctttttt ttctgatttt
    12421 aatcgattaa ataattcatt tgctgtttta tacatagcta tctcctcaaa aaagatatta
    12481 taactaagta taccatatta accttataaa aacgaccgct cattttttaa agcttctcct
    12541 aattgaatca ttttccaacc atttactttt ctactactaa taatttcgtc tgaactattt
    12601 acagaagtgt gacccgactt aatttcagaa gtcttaatat tttcattatt ctttacaaga
    12661 ctcctgactt tcaaggggat ataaaataac tctagatgta tggaatggca acacttttct
    12721 agacaaaaat tataaggtct gtttatgaca ccatatccag ttgcccttga caacgagcct
    12781 cctcaaatcg gttttcttag cggcgtgctc actttgaata aaataagccg ctcgaacaga
    12841 aggtaaccga ttcttgctca ttatcaaggg ttcgctacgc caacctccgc atagcgtacc
    12901 tcaattggtg ttttataacc aagagaacta tggatccgat gatgattcca ccaattgaca
    12961 taatcaaaac attctaattc taagtgtgcc atcgtttcaa attgatattg actcacaaat
    13021 tccgtcttaa aagctttgta agtcgcttct gaaacggcat tatcatatgg acatccaggc
    13081 ttactcaagg agcgttgaat gccaaatgtt tctaagataa gatcaatcaa ttcattatca
    13141 aattcttttc cacgatccgt atggaagagt tcgatttctt gaagtgagta aggaatgctt
    13201 tgaatggccc tttttacaag ctgcgcatct tttttatttc cgcaagaatg gccaataatt
    13261 tcacgattga ataaatcaat catcaaacaa atataagccc aatttgtccc gacccgaaca
    13321 taagttaaat ccgtgacaac cgctgacaat gcttttgttt gagtaaactt tcgatctaag
    13381 tgattcgcaa ttttcttttg attgctttgg cacgaatgta cgcgatattt gggcttcgtg
    13441 taactggatt tcaatcctcg tcttttcatg atgcgacgaa tttttcgacg actcaaaatg
    13501 agatttttct tatcaaggcg tttcttgatt ctgcgtgaac catatgctcg tctattttgt
    13561 tgaaaaactt cttccaccgc ttcttctaat tttgcttcta ctgcgccttg agtcgtttct
    13621 ttttctcgat aataataggt ggctcttgca atacccagta ctttacacat ggctgatatc
    13681 gagtatttgt gcttatttgc atcaattact tgtcttttcg tccgaatatc agcgccgctt
    13741 gctttaaaat atcattttct atcaagagtt gtttattttg ctttcgcaat tgaattaact
    13801 ctttttgttc aggtgttaag ttatcttttt ctttaaatga gccagaggta tttgcttgtt
    13861 tcacccattt atcaaaagta gacggggtta aatcatactc tctgataata tcggttctct
    13921 ttttccctga cgcatataac tgaaccattt gatttttaaa ctctttagta aacgttcgac
    13981 gtggttttct ttctgacatt aacaattcct ccagtgtgtt ttcttatatt ttacacacct
    14041 taatttttct gtctagttaa ttgtagccta tccaaacaaa cgttcatttt ataaaaataa
    14101 gagaaataat atcattatgt ttcataatat atatgttaaa ataattttaa aaaaaattca
    14161 atatgactat tcatttctag tttgcgaata tgactaaaga aagaaaaaag actttaccat
    14221 tagaataaat cagttataaa aaagagacgg taaatatcga tttctttaat tatctaatta
    14281 ctcttcataa tgatatgttt ttcatgctta ctttgtagcc agataattga aaataaaact
    14341 tatattttac aaatgataca tttattttaa taaagagaca tatcttaaac acaacttagg
    14401 ttatccaaaa aattaaaaaa ggaaaaaggt actgttattc caagtaatac cattattcaa
    14461 cttctggtgt tatatatctt gttttatatt tttgtatttt cgaaaatagg ttttacatgt
    14521 gaacattaat tagttatata ttaactatat tcttctattc ttcagctttt tgtgcttctt
    14581 tatttattag attatctatg attatatttt atttcagata atcttattgt tttttatctt
    14641 cttccatttc actaaattcc tctactacac catatctatt gacaatcaac caaataaaat
    14701 acagtatttc acgatatagt gtgataaata acaaaataga agcaataaag cttcttgtgt
    14761 taaaacaatt ataaaagaac taaataatta gcccttctat ctataaaaaa gtcaatagcg
    14821 tcactaggat ttcctaataa cgctattgat tttcttttcc tctgaaatta aatcagaaag
    14881 atttttcaat aatgataact gttttgatta acagctttta t
//
LOCUS       DAKCAA010000060        14676 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000060 DAKCAA010000000
VERSION     DAKCAA010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.060"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(46..412)
                     /gene="ssrA"
                     /locus_tag="OUE31_002113"
     tmRNA           complement(46..412)
                     /gene="ssrA"
                     /locus_tag="OUE31_002113"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(583..1356)
                     /locus_tag="OUE31_002114"
     CDS             complement(583..1356)
                     /locus_tag="OUE31_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCU0223098.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1500..1850
                     /locus_tag="OUE31_002115"
     CDS             1500..1850
                     /locus_tag="OUE31_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCU0223099.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1831..2547
                     /locus_tag="OUE31_002116"
     CDS             1831..2547
                     /locus_tag="OUE31_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0223100.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2547..3995
                     /locus_tag="OUE31_002117"
     CDS             2547..3995
                     /locus_tag="OUE31_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCU0223101.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4065..4574)
                     /locus_tag="OUE31_002118"
     CDS             complement(4065..4574)
                     /locus_tag="OUE31_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223102.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4564..5289)
                     /locus_tag="OUE31_002119"
     CDS             complement(4564..5289)
                     /locus_tag="OUE31_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223103.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(5512..7632)
                     /locus_tag="OUE31_002120"
     CDS             complement(5512..7632)
                     /locus_tag="OUE31_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCU0223104.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            7862..9040
                     /locus_tag="OUE31_002121"
     CDS             7862..9040
                     /locus_tag="OUE31_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HCU0223105.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9056..9814
                     /gene="aroD"
                     /locus_tag="OUE31_002122"
     CDS             9056..9814
                     /gene="aroD"
                     /locus_tag="OUE31_002122"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HCU0223106.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            9837..10322
                     /gene="ybaK"
                     /locus_tag="OUE31_002123"
     CDS             9837..10322
                     /gene="ybaK"
                     /locus_tag="OUE31_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HCU0223107.1"
                     /translation="MAKKKIVKRNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(10393..11646)
                     /locus_tag="OUE31_002124"
     CDS             complement(10393..11646)
                     /locus_tag="OUE31_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCU0223108.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            11763..13112
                     /gene="gdhA"
                     /locus_tag="OUE31_002125"
     CDS             11763..13112
                     /gene="gdhA"
                     /locus_tag="OUE31_002125"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HCU0223109.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13224..14570
                     /locus_tag="OUE31_002126"
     CDS             13224..14570
                     /locus_tag="OUE31_002126"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HCU0223110.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
BASE COUNT         4825 a         2614 c         3006 g         4231 t
ORIGIN      
        1 ataaaataag gatttaagca tctagcgaaa tctgctgaaa tctcacaatg gagacggcgg
       61 gagtcgaacc cgcgtccaaa cacatcgcca cttaaaaatc tacgttcata gtcaactcat
      121 ttaaggattc actttacagc ttgccgagtg acaggcattc tgtatcgcta gtctgatgtt
      181 ctctttttca acttacagac ggaaagttga aacgtatccc actaaagtta ggacccttac
      241 tcgagcacat gggcgatgcc gagaggatct acgctaactg tttttaggca gctaaagcgt
      301 aagagttgtt ttcgttttta gcagttatat ttaactgtaa cgtttttacg tagacgtaac
      361 ctacgaaacg caattcaagc tcgactgtgc ctgtcgaatc cgtaacgtcc ccgttagcta
      421 acaagggtta cgtgtatttt tcatacaaaa ttagtatagc atatattggg ataaattcaa
      481 taaaaaagcg aatcatatcc cattatttat ataataactg cccctttctt aagaaaaaat
      541 aagcgatttt cttaagaaaa gaggtagctt caaaaaaaga tcttaaatca gatcaaaata
      601 cttcaatgcg tggacaattc cgccttctgt atttttcttt gtgataaagg tagaaagttc
      661 ttttaatccg tcataggcgt tgcccatagc gattttgttg tcgcaagctt ccaacaaggc
      721 aaaatcattc ggaccatcgc caaatccaaa agtaggaact ttttccagct gaagttcttt
      781 ttgcagacgt ttgacacctg ccccttttga gattcctttc ttcactgtat cgatcgagta
      841 aggaccattc cgataaaaag ttagctcagg aaaatgttcg tgatagtatt cgtcacctga
      901 ttgagataag atcagcaaca tatttactgt gttttcttta aagcctaaag gatcaatttc
      961 cggaacatct gaatgaatga agtcgtaagc attgatcatt gtttggctat gaccggtaca
     1021 ccagattttc tgatcgttat agtaagaaag ttcatgaccg ttcaactgta catgatcata
     1081 cattttttga cattcttctg aagaaaatgt ttgagaatag atttcttcgc cgtctactcg
     1141 aatgaaagaa ccattcatgg tgaccgcaga agtaatgccc gcatcttcca tgatagagtg
     1201 gatttctgct tctgtacgtc ctgtagcgat gacggggaga acattgtttt cttttaatgc
     1261 gttcatagct tttgccactt cgggtgtgat ttttgatttc gcatctagta atgttccatc
     1321 aagatcaaag aaagtgattg cacgataatt tgacacaaat aaaactcctt ttttattgga
     1381 ataagtttat cttaacaaag aatgaacaaa agacaaacct ttcgtgaaga attcctgaac
     1441 atattggttc agtcaacaat ttagagtata ctataagaag agaatttagg agggaaagaa
     1501 tgattttttt cagtattggt atcttattct taataattgg cagtcttttt cggattctgc
     1561 cctcaaaagg aaatctgcct ttttatgggt atcattcgcc tcttgccgca aaaacagacg
     1621 ctcattggcg gctggctcaa aagacaagcg gaaactggtt ttttcttatg ggcttactga
     1681 tggcattgat cggctattat ttaaagacat ctgggcatac gaattatttt ctgattgaaa
     1741 tgcttctgct agtatttcca attatgccta tttttattat gacagaaaag aaattacaga
     1801 aatatgacct ggaaactgga gggaacgata atgaatattt taatgattga agataatcaa
     1861 tctgtttctg aaatgatgca gatgtttttc ttaaatgaag gttgggaagc aactttcaag
     1921 tatgatggaa aagaagggct cgatgccttt ttagaaaacc cacaacattg ggatatgatt
     1981 acactagacc tgaatttgcc cacactggac ggtatgctag taggaagaga gatccgcaaa
     2041 gtttcaagta ctgtgccgat tatcatgctg acagctagag attctgaaag cgatcaggtg
     2101 atcggcttag agatgggggc agatgattat gtcacaaaac ctttcagtcc tctgacgctt
     2161 attgctcgaa tgaaagcttt gcatcgccgt agtgagttgg cagaagcaag agaagaagca
     2221 gtagtttcag atgatcattt tgatatcgag actagtcatt tcaagatgaa tacgaaaaca
     2281 cgagaagcgt atctggacaa ccggccaatt gaaggactga cgcctaaaga gttcgatcta
     2341 ttgtttactt tagcaaaaaa accacgtcaa gtattctctc gggagcagtt gcttgaatta
     2401 gtctgggatt atcagtactt tggtgatgaa cggacagtgg acgcccatat caagaaatta
     2461 cgacaaaaaa tcgaaaaggt cggaccacaa gtcatccaaa ctgtttgggg agtcggctac
     2521 aaattcgatg attctggtgt tgcctaatgc gttatttgta tcagcaactc ttagctttct
     2581 gcggaatggt cgcgttgatc ttattgatcg ttggagtttc ttttacacaa ctgacaaaac
     2641 aaacgattga agaaaacaat taccagcaac tgtttggata tgctgaatca gttgaaaaga
     2701 caacgcaaac ctatgccgat acgctcccgc agtttagtca agatcaggcg tttcaaaatg
     2761 cattgctgct gacagagcaa gtactgacag aacaaaatgt gaactttata tttatcgata
     2821 aaaacgaacg tgtcatttat ccgactaata cagctttact gaattttacc ttaacagctg
     2881 atcaatggaa aaatctgagg aatggacgtc aagaaaaatt cacatcgaat aaaaatattt
     2941 taggacaagc acaggcgacc tcttacgcac ttgtgccatt taatttgaat catgaattct
     3001 atggagcact tgtagttagt caacctgcgc gaaatatcga taacagcgtt cgtccaatta
     3061 cactgaacct gttcaaagga tttatttttt ccagtatcgt tgcagttatt gccagctatg
     3121 cttttgcagc attccaagtt aagcgtatca atcggttaag gaatgcgacg aaagaagtga
     3181 cgaatggtaa ttttgatgta cagctccccg tacatgacaa agatgaattt gatgagttag
     3241 cagatgattt caataaaatg acgaattcat tgaaagaatc tcaagcagaa attgaagaac
     3301 aagaaaatcg tcgaagacaa tttatggcag atgcttctca cgagatgaga acacctctta
     3361 cgacaatcaa cggacttctg gaagggttag aatacaatgc aatccctgaa aatcagcgag
     3421 aaaacgcgat taaattgatg aaaaatgaaa cagagcgtct gatccgtttg gtgaatgaaa
     3481 acttggatta tgaaaaaatc cgtacgaatc aaatcagtat ggtcattaaa aaattcaatg
     3541 gaacagaaac attgaaaaat attgttgcac agttagaagc taaagcagaa gcagcaggag
     3601 atacattgac attgaaagcc gttgatgata ttgatgttta cgctgattat gaccgatttg
     3661 tccaaatcat ggtcaatatt attcaaaacg cgatacagtt tactgaaaac ggccaaatca
     3721 cgattacttt agaaaaaggc tatcttgaaa cgatcatcac gattgaagat acgggaattg
     3781 gaatgtctga acaacaaatg aaaagtatct gggatcgtta ttataaagta gatccttcaa
     3841 gaaaaaatac aaaatatggt gaatcaggat taggtttacc aatcgtgcag caacttgtac
     3901 gcttgcataa aggaaaatta gaagtagaaa gcgaactagg aaaaggaaca aaattcgctg
     3961 ttcgtttgcc tgacgtagaa atcaaaaaag agtaaaaaac aagcggtata aaagatcatg
     4021 aatcgatctt ctataccgct tgtttttact ataaaatgat tgatttagcc cgcgggctct
     4081 aaacgatcaa tataaggact ttgagcaata gtagcatcat gagtaaagag taagatacct
     4141 tgattttctt catgagctaa ataagaaagc aagtggagta gctcttggat ctccaataca
     4201 ctaagttcat caaatgtatc ttcaataaca atattgtttc gcttggaaag caaggcatga
     4261 agtaattgca gctttacttt ttcaaaagac gtcaactcag ctgccgcaca attaagcaag
     4321 gaaggagaga tatcaagttt ttcttgatag gccaaacgat cttgtttgat ttctttttcc
     4381 ggtacatcca acaggacatg gtctttaaga ttcagataag gaaacatcgg ccaatttttt
     4441 tggatgatcg caaaattatc cagttttgca acaagaacct cttttttcaa gtgctccaat
     4501 attttatgct gtttttcgag aggacacaaa ataacggtca agtgttcagc atgaatcaaa
     4561 tattcaggtt tcattacgtc caggcctcct actttgcaaa tgatggataa aaaaagtgaa
     4621 agggaataga ctaagaatga gacagcatcc actgagccca ataagagttt gggcaaatcc
     4681 cttaagtata tctgtgaaaa aaagatcatt ttggaaatcg atggtaaaaa aagtctgttg
     4741 atccatcgga attgtaagtc cgcttaccga agtcaagata tcacggatat ctggcagttc
     4801 agtagtcttt aagacaagaa aattgatcct ttgaagaagc gcttcataaa ctgactggaa
     4861 gcttacgatc cacaataaaa ccaagataca acaaagaaag agaggaaaga acagctgcca
     4921 gaaaataaaa aggaataatt tggttttaga aagaccagtc aggtgccaat tgatcaattc
     4981 ctgcttgttt tgcctgactg aatagtaaaa gaaaaagata aaaaggaagg caaatagaaa
     5041 aaataaactg aatatgcctt ttatataaaa tcggctagct aattctaaag ccggaagaag
     5101 ctctgtagat gcagaagcgc caataaatga aagccgatct tggacttgat tggctaaagc
     5161 cgattgcaaa tggtaaagag tcaggcatgc tatcaataaa aaagcagaaa agcttgaaaa
     5221 taaacaatag agtattgtct gctttttgta ataaattaat cgagcagtag catagcggat
     5281 tattttcata cttttcacct ctataaaaag tatagagaat gaatatgaat aaagtatgaa
     5341 attcctttag tgaaatcacg aattaaaacc agaaaatatt ttgtaaaaag caagaggttg
     5401 tgaagaagct gccctattct attaccgtag atgcaagctt ttgaacactg tttattcgaa
     5461 aagaggagca gcgacaataa ttttgtcgct gctcctttta aatttatttt atcattcgga
     5521 agaacttgtg gtcgttccgt gaagttcttg gtacgtttgc gttttataaa gatcaacagt
     5581 tgattgtccg ttgtgttcac taaagacact agttgacttg tcaccaagag atttttcagc
     5641 ttcttttaat ttctctaagc cattcttgta gtcataatca ctggtatcaa ttgggtctaa
     5701 tccactattc gtatagaacc gaagaagatc accattattg atttggtcag aaacagctaa
     5761 ctgtttatca actttttctt tcagtgaatc aatttcattc tgtacttcct cagtaggttc
     5821 agtaatagct tcaccagttt cgttactata gatcgtacca ccgtagtaag tatattttgg
     5881 tgtaacaaaa tcaccatcac ggaaagaaac aagctgttca tgatctttcg agaatagatc
     5941 ttgtcctaac tgaatataat tttttgtatc tacacctagt aagtgaagta atgtaggcaa
     6001 ggcatcaact tgtccgccgt aagtgtgatt gattccgccc tgtgtttgtc cagggatatg
     6061 gatcatataa gggacacgct gcatttgtgc attgtcgtag tttgtccaag tagaacttgt
     6121 ttttccaact aattcagcta gatttttatt tcttgaattc gagacaccgt aatggtcacc
     6181 gtaaaggacg atgactgaat tatcatacaa gccgctttct ttcaaataat tgaagaattc
     6241 ttgtacggcg gtatctaaat aattggctgt cgcaaagtaa ccgttgatcg tttcatcatt
     6301 tgtattggct aacgggaatc ctgcttcgtc attggtgaat tttgaataag gataatggtt
     6361 agatacagca atgaattttg aataaaatgg ttgttgcaga cgttccaagt attgtacgga
     6421 ttgttggaaa aatggtttat catgcaaccc gtattggaac gaattgtcat cattaacatc
     6481 ataataagaa gaatcaaaga aataatcata tcctaaattc ttgtatgtct cgtttcgatt
     6541 ccagaatgta ccagcgttcc catggaatac cgcactaatg taaccttgtg tttgacttaa
     6601 aatatcaggt gcagcttgga aagtattttt tccgcctaat tgtgtgaaca aggagccttg
     6661 attcaagcca aacaatgaat tttccatcag cgtttccgca tcgcttgttt ttcctgcttt
     6721 tacttgatgg aaaaagttgt caaaactgaa cgtgctgttg ctgtggtaaa gactattgat
     6781 gaaaggtgta acttcatgct ggagaccatt ctcatctgtc aatttataat cgatcaggaa
     6841 ttgctggaag ctttctaaat ggatataaat cacatttttt cctctagcga gcccgaacaa
     6901 atcgtcattt ggtgctgcat aatgttcttt tacataattt tctacttctt tcatatcatt
     6961 gggacttgct tctgcccgca cttggtttgt ctggtaagtt tgaacaccgt cataaaccat
     7021 gaaagcattc aagccaagat atttgaccaa ataatcacga gagaatgttc gagtcagcaa
     7081 ttctggacga tcagcttccg ccataaaaag atttcctgag aaaatcataa ctgctaatgt
     7141 agagatcgca aaagccattc ttgctcggat cgggcgaggg tccaacttga ttttttttgc
     7201 aatcagcaga acagtcaaga taataaaatc gatccaatag atcacatcat atgggcgaaa
     7261 cagtcgaatg gcactttctc ccagaccact cgctactttc ccagcaccta aaatcgtgtt
     7321 gatcgtaatg aagtccgtga attctcgata ataagtgaca ttcgaaaaaa caagcaatgt
     7381 caaaagaaaa taaatgacca tcatcgtgat ataagcaact ctagggcgtc tgatataaag
     7441 agcaattcca agtaataaca atgtagttgc aatagggttg ataaacaaga taaagtattg
     7501 aatgccactt tcgattccga gatggaaatc aactaaatag gcaaaaatcg ttttcaacca
     7561 aagtaaaacg actagtaaag aaaaaaatcc gagcctctta ttcaaaaagg caggtgtttt
     7621 tatacatttc aagataatct tcctttctgc acttcttaat cacagaagtg tcctgaaacc
     7681 atgttacaca gctcacttat tctcatttat tttactagta tgacaatata gtgtcaattg
     7741 aaaccagaag tttatgctgt ttcattaagg ttttctttaa gcttcatgaa aaaatgagca
     7801 gtaagacaag tcctatgttt tttgttatac ttgggaagag aaagctaaag caggtgaagg
     7861 aatgaaagta aaagtaaaaa aaagagcaag caatcgattg aaaaaaggat atccactgat
     7921 ccaaaaagaa gaccttgctc atccccaaaa agaaaccacg caatgggtgg aattagttga
     7981 ttcgcaaaac caatttatcg caaaaggata tctaggaaag cagaataagg gaatcggttg
     8041 ggtattgagc cagcagaaca tcccatttga tcaatctttt tttgaagaat tttttgtgaa
     8101 gtcaaaagaa aaaagaactt tctttttttc agatgattct actaccgctt ttcgtatatt
     8161 caatggagaa ggagacggga tcggcggtct gattgttgat tattatgcag gttatgctgt
     8221 tttttcttgg tataacgaaa cgttatatgc acatcgtgaa ttattgattc aagcttttcg
     8281 tgaaatctac ccggaaatca taggaggcta tgagaaaatt cgatttgaat cagtaaatct
     8341 gcctgagagc cagttcattt acggaaaaga ggcaccggaa cccttgatcg taaaagaaaa
     8401 cggagtaaaa tttgccgttt atttaaatga aggattaatg actgggatct ttttagacca
     8461 aaaagaagta cggggatcat tagcagaagg tttcgcttct gggaaaacag ttttgaacat
     8521 gtttagttat accggcgcct tttctgttgc tgccgcaatg ggaggggcaa tcgaaacaac
     8581 aagtgtcgat ctagcaaaac gcagtttaaa aaaaacacag gaacagtttg aagtgaatgg
     8641 tttggatgtc gatcagcaaa aaatcattgt tatggacgta ttcgagtatt tcaaatacgc
     8701 caaaagaaaa caatttttat atgacatgat tgtattggat ccaccaagtt ttgccagaaa
     8761 taagaaaaaa gtctttcgcg tagcaaaaga ttatggggaa ctggtcaagg atagtctgga
     8821 tattttagct gaagacggga tacttattgc gtctacaaat gctgcgaatg tctcgataga
     8881 acaattccaa acaatgattg aagaggaatt ccatgccaaa aatgtttctt ttgaacaact
     8941 tgctttatat cgtctgccaa aagatttcca gacgacggat acctttttag aaggcaatta
     9001 tctgaaagtg tttgtttatc aaattaaaaa taaccattag aaggagcgat gcagaatggt
     9061 tcgggtaaag ggattgaata taggaagcgg tagaccaaag atttgtgcgc ctcttatcgg
     9121 ggccgtccga gaggaagtat tacgtgaagc agttcttgca cgtgaagcag gggccgattt
     9181 agtcgaatgg cgagtcgatc attatcgtga ggttttttct tttgatgaag tagcagaaac
     9241 attggttctt atccatgaga tgcttgatgg actgccgtta ttatttacgt ttcgtacctt
     9301 agctgaaggc ggagaacaag acatatcgat ccgtcagtat cgcgaccttt atgaacatgt
     9361 gatacacaca ggattagtag atatggtcga tatcgagttg ttcaaagtag aaagtctagg
     9421 aaaaagactg atagaggaaa tcaagtcttt aaacattcct ttaattatca gtagtcatga
     9481 ttttaaagaa acaccagcag accctgtctt gctttaccga ttgaatgtta tggaacattt
     9541 tggagccgat atcggaaaac tggcagtaac tcccaataat gaacgagatg ttttgcggtt
     9601 gatggagttg actagacggg caaatgcttt tgtctccatg cctattatta cgatgtccat
     9661 gggaaatctt ggtaaaattt ctcgtctggt tggcggaacg acgggttccg ttatgacatt
     9721 tggttcctta agcagcgatt ctacttctgc tccaggacaa ttaccggtca aagcattgaa
     9781 gcaaattatt caattattaa atgaaccgtt gtagaacaag tttgaggtga tattttttgg
     9841 caaagaaaaa aatagtaaaa aggaatgcaa tccgtatggt cgaacaaaaa aagattccct
     9901 atacagagca cgaatatgag tgggacgaaa gccacctaag tgcgtcatcg gtcgctgaac
     9961 agcttccaga aagccaatct cgtatattta aaacactggt tgctgtgggc aatgtgacgg
    10021 ggcctcttgt tgctgtgata ccgggagaag ccgaattgaa tctaaaaaaa ttagcaaaag
    10081 tttcagggaa taaaaaagta gaaatgctcc atttaaaaga tttggaagca acgaccggat
    10141 acatacgtgg tggctgctcg cctataggta tgaaaaaact atttcctact tatttagatc
    10201 aaattgcaga aagctatgaa caaatcattg tctcggctgg cagaagaggg ctacagatgg
    10261 agttagcacc tcaagatatc tgtgcattaa cgagcggaca atttgcagat ataaaacaat
    10321 aaatcatacg tataaaagaa agaaggaggc cgggatgttg tttgtccagt ctccttcttt
    10381 cttttttata cattatgctc tttgcccggc attcattcct gctacatgcc ctgtagcgaa
    10441 agccgctgtg atattaaagc cgccagtata accattgaca tccagtaatt ctcccgcaaa
    10501 atacagacca tcaatgattt tactctccaa tgttttagga taaatttcct ttagagaaac
    10561 ccctccgcca gttacaaatg atttctcaat aggaaaagtt ttgttgattg atagcttaaa
    10621 ctctttgcat agttgaacaa aatcttgaat ttgtttttga gaggcttgtt gtcctgtcag
    10681 atgatccatt tcaagccgct caagaaagaa aactaacaat cgctcaggca atataccatg
    10741 ccaagcattg accaagttct ttttggttgc tttacttttt tctgtcaata tatgaataag
    10801 ctcttgtttg gtttgtgtag ggaaacaatc cagagaaagt gtcactggtt ctcccgtttt
    10861 ctctaattct ttattgacaa aacttgaaca acgcagtgca gccggaccag aaataccgaa
    10921 atgggtgaaa agtaaatcca tcgtatgttc agtcaataca cgaccttttt tatttaaaac
    10981 gcgtaaagtg atgtcttgta aagaaagccc ttgaagtgtt ttctcctgaa tatacggttc
    11041 atccgatatc aagggggact ctgtcgcata aagaggcgtc accgtgtgac ccactcgctt
    11101 cacgatcttg tacccatctc cagtagaacc agtagatgga taagtccgtc caccagttgt
    11161 taagataatg gcaggagcat ggaactcttc gaattccgtg cgtataccgt aaattttatg
    11221 ttctttgtgg atcaatttct ctactcgagt agagaataga agcgtcacat ctagttcttt
    11281 cagacgattg agcaatgctt cgataatcgt ttttgattta tttgttacag gaaacatccg
    11341 tccatgatcc tcttctttta aatgtacgcc ttgtgattca aagaagttca tgatatcgaa
    11401 attattccat tgcgcaaacg tactatataa aaactttcca tttccaggaa tatgtgcaat
    11461 caaatcatca acaggacgat tgttcgtaac attgcaccga ccaccacctg tcatcagtag
    11521 tttttttcct gcttttttgt ttttttcgat caagagtacg cgtgcgcctt gttcagctgc
    11581 actgatcgct gccatcatcc cgcttgttcc agcgccgact acgatcacat catacagttt
    11641 ttccattccc tcacctcaag gaaagtgtag catatctgaa gaaagaaaac agaaaaaaat
    11701 gttttgagcc aaaagagaaa atgagctaaa atgagggaag ataagcaaag gagcgtggaa
    11761 cgatgacaaa cgcaacagaa tatgttcaag caattcaaga aaagctacat caaaaggatc
    11821 aagggcaaga agaattttta caagcaatcg atgaattcat gcccacggtt atgtcttttt
    11881 tggacactca tcccgaatat atcgaaaaga atatcttaga acttttaacg gaaccagaaa
    11941 gagttattca atttcgagtg ccttggcaag atgatgaagg aaactggcga gtaaatagag
    12001 ggtaccgtat ccaatacaac tcagctatcg gcccttataa aggtggattg cgcttccatc
    12061 ctagtgtcaa tctaagtatc ttgaaatttt tggcttttga acagattttc aagaatagtt
    12121 taaccggtct gccaatcggt ggaggaaaag gcggaagtga cttcgatcct aaaggaaaat
    12181 ctgataatga gatcatgcgt ttttgtcaaa gtttcatgct ggaattgtca aaacatatcg
    12241 gcccatcgat tgatgttcct gcgggagata tcggtgtagg agctagagaa atcggctatt
    12301 tgttcggcga atataaacga ttgaaaaaat atgatactgg tgtgttgaca ggtaaacctt
    12361 tggatttttg gggaagtaag atacgtacgg aagctactgg ttatggatta gtgtattatg
    12421 tcaaacatct attgaacgaa gaaaaagatt catttaatca aaaaacagtt tttgtttccg
    12481 gaagcgggaa tgtagccatt tatgcaatcg aaaaagtgca agagctaggc gggaaagttg
    12541 ttacatgttc agattctagc gggtacatct atgatccaga aggaatagat gtgaaactat
    12601 tgaaagaagt caaagaaatc aatagacaac gtttgacgga atacgcaaac caacgtcctt
    12661 ctgctattta tcatgctgga gaatctgttt ggacattgaa agaaaaagcg gatatcgctt
    12721 tgccatgtgc tactcaaaat gaaatagacg aaagcttggc cgaaatctta gtagaaaatg
    12781 ggatcaaaat cgtagcagaa ggcgctaata tgccatgtac agtaaaagct gtttctgttc
    12841 ttcatgaagc aggcgtgtgg tattgtccag gaaaagctgc taatgctgga ggagtagcag
    12901 tatctgcttt agaaatgagt cagaacgtcc agcgattgac ttgggaaaga gagcaagtgg
    12961 atgagcagct ggatcaaatc atggaaacga tttaccatac gtgtcgccaa acagcagccg
    13021 agtacggcga cgaaaaaaat ctgcttcttg gagcaaatgt tgctggattt gaaaaagttg
    13081 ccaaagcaat ggcagcagaa ggtttagttt gaaaaatgaa actttcttgg aaatattgtc
    13141 agcattttgt ttatttgctt gaaaaataat aaaaaaaaac gtaaagtatt acctgtagag
    13201 taaacctata aggaggagaa caaatggcac acattcattt tgactattca aaagtagcac
    13261 cgtttgtcaa cgaacaagag ttagggtaca tgcaaagcca agtaacagca gcccacaacg
    13321 aattacggga aggtactggc gcaggaagcg acttccgcgg ctggatcgat ttaccaacga
    13381 actatgacaa agaagaattt gcacgtatca aagaagcagc taaaaaaatc caatctgatt
    13441 ctgaagtatt agttgttatc ggtatcggtg gttcttattt aggcgctcgt gcagcgatcg
    13501 acttcttgaa tcacacattc ttcaatttat tagatagcaa cacaagaaaa gcaccacaaa
    13561 tcttctttgc cggaaattca atcagctcaa catatattgc tgacttgatc gaagtaatcg
    13621 gtgatcgcga cttttcagta aacgttattt caaaatctgg aacaactact gaaccagcga
    13681 ttgcgttccg tgtattcaaa gagcttcttg ttaagaaata tggacaagaa gaagcaaaca
    13741 aacgtatcta cgctacaaca gataaagcaa aaggtgcagt taaagtagaa gcagatgcag
    13801 aaggttggga aactttcgtg attcctgatg acatcggcgg acgtttctct gtattaactg
    13861 ctgttggttt gttaccaatc gctgttagtg gtgcagatat cgatgcattg atgcaaggtg
    13921 ccgctgatgc aagcaaagca tactcaagcg acaaactaga agaaaacgaa gcttaccaat
    13981 acgcagcaat gcgcaacatt ctttaccgta aaggcaaagt aactgagttg ttgatcaact
    14041 atgaaccagg aatgcaatac ttctcagaat ggtggaaaca attgtatggt gaatctgaag
    14101 gaaaagacca aaaaggcatc tatccttcaa gcgcaaactt ctcaactgat ttgcactctt
    14161 taggacaatt catccaagaa ggacgtcgca atatttttga aacagttgtg aaggttgaaa
    14221 aacctcgtaa atcaatcaca attcctgaac aagcagaaga tttagacggt ctaggctact
    14281 tgcaaggaaa agaagtggac ttcgtaaata caaaagcatt tgaaggaaca ttgcttgctc
    14341 atacagacgg tgacgtgcct aacttgctag tcaaaattcc agaaatggat gcttatacat
    14401 tgggttatac aatgtacttc tttgaaattg ctgtaggtat ttcaggttac ttgaatggaa
    14461 tcaacccatt cgaccaacca ggtgtagaag cttacaagaa aaacatgttc gcacttctag
    14521 gcaaaccagg ctttgaagat cttgctaaag aattgaacga acgcctgtaa gataagggtt
    14581 tttcgctaga tttaaataat cagtgataga aacatgttcg ctttaaaatg aaaactggta
    14641 cccatttagg tactcaaaca tactgcatcg tttatt
//
LOCUS       DAKCAA010000061        14186 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000061 DAKCAA010000000
VERSION     DAKCAA010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.061"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            185..1000
                     /gene="thiD"
                     /locus_tag="OUE31_002127"
     CDS             185..1000
                     /gene="thiD"
                     /locus_tag="OUE31_002127"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HCU0223111.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1205..2656)
                     /gene="cls"
                     /locus_tag="OUE31_002128"
     CDS             complement(1205..2656)
                     /gene="cls"
                     /locus_tag="OUE31_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCU0223112.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            2998..5664
                     /locus_tag="OUE31_002129"
     CDS             2998..5664
                     /locus_tag="OUE31_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCU0223113.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6028..6780
                     /locus_tag="OUE31_002130"
     CDS             6028..6780
                     /locus_tag="OUE31_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCU0223114.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(6802..7956)
                     /locus_tag="OUE31_002131"
     CDS             complement(6802..7956)
                     /locus_tag="OUE31_002131"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HCU0223115.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8141..10582
                     /locus_tag="OUE31_002132"
     CDS             8141..10582
                     /locus_tag="OUE31_002132"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HCU0223116.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(10912..11616)
                     /locus_tag="OUE31_002133"
     CDS             complement(10912..11616)
                     /locus_tag="OUE31_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223117.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(11803..12048)
                     /locus_tag="OUE31_002134"
     CDS             complement(11803..12048)
                     /locus_tag="OUE31_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223118.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(12065..12916)
                     /locus_tag="OUE31_002135"
     CDS             complement(12065..12916)
                     /locus_tag="OUE31_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCU0223119.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            13082..14086
                     /locus_tag="OUE31_002136"
     CDS             13082..14086
                     /locus_tag="OUE31_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HCU0223120.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT         4571 a         2503 c         2973 g         4139 t
ORIGIN      
        1 ttagaatagc gaatacaaac aaatgacaac tattttctga tttattacaa atgttttttc
       61 aaataaattt gattaccaag aaaaggtagt ggtatattta ctgagggata ctttgaaaaa
      121 catatgatag aaacagtaac agcattatga aaaatctttt tataaaaatg gaggaatcga
      181 tttgatggaa gatcagtatg tacaagcaat gacgatcgca ggatcagata gcgatggaag
      241 cgcagggatg caagcagata tgcatacatt ctttacaaga aatgtttacg gtgtttctgt
      301 catgaccgca tgtgttgcag gtaattctta cggaatcgga gcaagtgtga cattgccaac
      361 agattttatc gacaaagaat ttgaactgat tgcgaaggac tttcaaatac gtgcagctaa
      421 aacaggtatg ctagcagatt caaagttgat tgagacagtt gtaaaaaatt accaaaaata
      481 tgattttgga ccattagtcg tggatcccgt aatcgtaacg aaacatggaa atcttttact
      541 agaagaatct gctttgcaaa gcttgaaaga aaagcttgtc cctttggccg aagtactgac
      601 acctaatttt tatgaagcag aaaagctgac tggacggaca ttagcagctg aagaagattt
      661 tgtgcaagca gcaaaagaac tgcaagatat gggtgcaaaa aacgttatga tcaaaggaca
      721 tcatgctaaa gatgcgcagc aagaaacagt caatgactac gtattgctcg aatcaggaaa
      781 atcgttttgg ttaaatgcac cattttatcc taccgaccgg atcaacggaa ctggcgattc
      841 gctatctgca tgtattgcag ctgagttagc gaaaggaaaa acagttgaac aagcgatccg
      901 attggcaaaa gactatgtaa accgtgcaat tcgtgaagaa ataaatgtag ggcacaaata
      961 tggacccatc aatcattggg cagctggtga attagagtaa aagaaagagg tcgtgagcct
     1021 gccgtccagc tccgagtcac aaggaacaag ttcaaaaaac agcttctcat gtttgttgaa
     1081 tattgtgact tgtgaccgag gagttggcag gagaacaccg tttgttcgga agaagggact
     1141 gtgacaagat ttttgtcaca gtccctttaa tcttagtata tttttctcta cttgaataaa
     1201 aaaattatag gattggagaa aataatcgag aaatttgttg cttgaataat agccagttag
     1261 acatttcctt gactgtttca gttgtcatgg atgaacaatg tgtctcatct tctttgaact
     1321 gagtagcaag ttcttctaaa aactcaggat cgtaaatgac agcacttgtt tcaaaattca
     1381 atcggtagct acgaatatct tgatttgctg aacctaccat gcagatttca tcatccatta
     1441 tcaatgtttt tgcatggagg aagccgttct catagacaag gatttgtaca ttttccttga
     1501 tcagctgccg agcataatat tgtgttgctc gataaataaa aggatgatcc ggtttgttgg
     1561 gaatcatgat tttcacatct acaccagagg cagttgcgat ttttaaagca gcaatgacac
     1621 tttcatcagg aacaaggtaa ggtgtctgta tccaaacacg ttttttagca gaagtaatca
     1681 atttgataaa tgaaagcttg atttgttccc tttcgttatt cggtccgctt gaaacaagct
     1741 ggatggatgt atcagcaagc ttagattcat ctcgatctgc ttttttaaag aaataattca
     1801 aatgatagcc gacctttttt tcttcaggta ccgagacgtt ccagtctgtt aagaagcgaa
     1861 gctggagcaa agaagaagcg gcaccgaaaa tccgtatatg cgtatcgcgc caatagccga
     1921 atttttttgt tgtatttaca tattgattgg caatattgaa accaccggta taactaatct
     1981 ttccatcgat cacaacgatt tttcggtgat catggtaatt caatcggaaa cgaagtaatg
     2041 ccttttgtga ggtaacaaat gtatggacat gtccaccatt tttgattaga cgattgaaat
     2101 cttttgcttt tgtaccatga gagccaaatg catcatataa tattcgaact tccacgcctt
     2161 ctgcggcttt ttcttctaaa acatgtaaga cttgctggcc gatattatct gtcacaaatg
     2221 cgtaatattc gatatggatc gaatgtttgg ctttttttag atcttgaagc agtgaatcca
     2281 atttctcttg tccgtctgtg agaagagtga cagaattcat tcttgtcagc ggcatacgat
     2341 ttaatgaaga gaagaagtcg acaaattgct gtttgtcttt atcgcccatg tcaggatcgt
     2401 aatgttcaat ggtatctcct ctaaaagact gaaagttttc taattctttc aagtcacttt
     2461 gtcggagata gaattttttc ttatccgtta atccacgtcc gaaaaataaa tataatacaa
     2521 agcccacccc aggaagggca aacaatacta agagccatgc ccaaatggct gctacatctc
     2581 ggggtttgat caaaatagcc accaaagcaa taagtgcatt taatagataa agggcggtta
     2641 taatactaga taccacaaaa atgttcctcc ttacatacaa taacattagt atagcatgat
     2701 agaagaaaga agcctaccaa ggtgaatata cttttcactc ctttcatgaa aatgtaggta
     2761 aatcgggcta aagtagttgc tttttgtagg ttaataaggt aggatattag tacagttgaa
     2821 tatctcctta ggggagtaac cggcaacgtt tgttgcgata atatcaacag taagttaacc
     2881 aaatggtttt ctggtattgt atgaaatggt gagacctaag acaaatgcgt atttgtctta
     2941 ggtctctttt tttttcagac aggactaggg ccaagatcaa aaaatggggg atgaaatttg
     3001 gaaaacaagg aacaagcaca acaagcggtc tataaagaaa cgatcgactc gttgatgcag
     3061 caaacgcaga gctcaaccga tggattgagc accacgcaag cgaaggaaaa attagaaaga
     3121 gatggcttga accagctaaa agaaaagccg aagaagccaa cttggaaatt gttcttagaa
     3181 actttcaaag atgcaatggt tatcgtattg ctgattgtcg cactgattca gatggtcatg
     3241 ggtgactaca tcgaattctt agttattttt gcagtattga tgttgaattc tataatcagt
     3301 gttgtccaaa caaaaaaagc agaaggttct ttagaagcgt tgaaaaacct ttcagcgccc
     3361 gatgctcgag tgattcgtga tggtaaggaa aaaacgattc cggcaaacga acttgtggta
     3421 ggagatatcg tgttgttaga cgcaggcgat tatgtacctg ctgatggacg tttactagat
     3481 gcgggatcat taaaagtaga tgaaggtatg ctgacaggag agtcgacttc tgcagaaaaa
     3541 gaagtaacgg atatcacaag tacggtacca atcggagatc gtacaaatat ggtattcagt
     3601 ggaacgatcg taacttacgg acgcggtaaa ttcttagtga cttcaactgg gaataatacg
     3661 gagatcggac aagttgctgg ccttttggaa tcaacaactg agcaagtcac tccgttacaa
     3721 cgaggtctgg ataaattcag taaaaaacta agtctggcta ttttggcatt gtctttattg
     3781 attttaggta tccaactgtt tcgtatttat cttggagaag gtacaggaga tatgactgca
     3841 gatatcgtca gcgcagtgat gtttgccgta gccgtagccg tagctgctat tccagaagca
     3901 ttacagtcta tcgtaacaat cgtgttatct ttgggaacga ataaaatggc aaaacgtcat
     3961 gccattattc ggaagcttcc agcagttgaa acacttggtt cgacaagtat catctgtaca
     4021 gataagactg gtacattgac acaaaacaaa atgacagttg ttgactactt tttaggtaat
     4081 ggcgatactg gggatttcac aaatgaccct tcaaaatgga cagctgacga acgtcgcttg
     4141 atcgaaatca gtgttttagc gaatgatgca tcgatcagtg aagacggtac taaattgggc
     4201 gaccctacgg aagtagcgtt tatcgacttt agtgaaaaat taaaccagcc ttatcaggaa
     4261 atccgaaaca actacccaag acaagcagaa cttcctttcg attctgatcg aaaattaatg
     4321 tctactggac acacgatcga taacgaaaat tacttgtttg tcaaaggcgg accagatatc
     4381 gtcttccaac gcagtaaaaa agtattgcta aatggtgaag tcgttccgat gacggatgaa
     4441 ttgatgaaaa aattccaaga gcaaaatgaa gctttttcaa cacgcgcatt acgtgtacta
     4501 gcttttgctt accgtccact tgataatttt gatttatcat ttgaagatga agacgatttg
     4561 atccttgttg gtttgcttgc tatgatcgat cctccacgtg ctgaagtgac tcaggcggta
     4621 acagaagcaa gaagtgcagg aatcaaaaca atcatgatta ctggtgacca caaaacaaca
     4681 gctgttgcta tcgcaaaaca aatcgggatt tttgaagaag gaaacctggc tttgaccggg
     4741 acggaactag atgaattgac agaagatcaa ctaaacgaag ttttagaaaa agtcactgtt
     4801 tatgcacgtg tttcacctga gaataaaatt cgtatcgttc gtgcttggca aaataaaggt
     4861 catatctcag ctatgacagg tgatggtgta aatgacgcac cagcattgaa acaagcagac
     4921 atcggaattg ctatgggaac gggtacagat gtggcaaaag atgcagcagc gatggtattg
     4981 acggatgata actttgcttc tattgtcagc gcagtagaag taggacgtaa tgtgtttgat
     5041 aatatcaaga aagctatttc ttatctattt gcaggaaatt taggtgcgat cattgcgatc
     5101 atctttgcct tagttgctga ctggtccaat ccatttacag cattacaact gttgttcatc
     5161 aatttagtca atgattcact gccagcaatt gcattaggta cagaaaaagc tgaacctgct
     5221 acgatgaacc gcccgccaag agatccaaat tcaggaatct ttacggacaa aacattgatt
     5281 tctgtaacgt atcgtggtgt gctgattggg attgctgtta tctttgctca atggcttggc
     5341 atgcagcatt cacctgaatt cggtgtagcc atgtcatttt caacattgat ttggtgtcgg
     5401 acattgcaaa cattcccagc acgttcaaac acacaaacag ctatccaagc agggttcttc
     5461 tctaacagaa gtgtcttact agctgtagtt gtatgtagcg cgctttactg cttaacaatg
     5521 atcccaggac tgaaagaagt cttctctatc ccatcagcat ttggattgac agaagtcttt
     5581 acatgtatgg gaatcgcact tgtgacaatt gttttgatgg aaatcactaa attgatcatt
     5641 gtacgagtac aaggaaataa ataaaacgaa tcaacgaggt tgtgagcctg ccgtttaatt
     5701 ctgagtcaca aggtgcaatt tcaacaaaca gcttctcatg tttgttgaat attgtgactt
     5761 gtgaccgaag agttggcagg agaacaccgt ttaaggaaga agttgtaaaa tcagcatttt
     5821 gagctaatac tgagggtcat ctgattggac actgtttatt cggaaagagg gactttgaca
     5881 cgactttggt cacagtccct ttttttattt atgatagacg gaaagccaat cattttatta
     5941 ttcatcaaaa gagatagaat agataaaaga ggagaataat ttattccgaa aagtgaaaac
     6001 atataacaaa aaattagagg aaatcaaatg aatgaaaaag aatgggatga atttgctgaa
     6061 gaatattatg aaatccagca agaatcgcaa gtaactattg ctgaagatgt aaaaaattat
     6121 ctgaaaacgg agaaagtcct gcctgctgaa acagcagcag acgttgctgg aggatctggc
     6181 agatttcttt ccttagcaaa agaaattaat cgctatgatt tgatcgattt ttcttcagga
     6241 atgctagaaa atgcaaaaaa agaagcagaa aaaaatgagt tgccaaatgt ttcctttatc
     6301 aaacagtcgt tagaagaatt tatccaatca aatgagacat atgaaatggt ttttacagca
     6361 gcaaatccag cattggtaca tcttattcaa ttagaaaaat tgatgaaaaa gtcaagcaaa
     6421 tggtgcgtga taatcagggt agtggaatca atcgatgatg ttttttatcc tatcgaaaag
     6481 caactaggaa tgatagaaga agatcctaat acatcgccag ttgtaatgga tcaatttgaa
     6541 acatacttaa ttgatgaagg attcaaagtg aagaaaaaag attttactta ttttacacag
     6601 gaatcaatta ctgaagaatt gatgaagcta tactatgacg cgtacgcaaa agatcctgtt
     6661 gtgaccaggt acattcgcaa actattcagt gaaaaacgag aaatccttag tacgactaag
     6721 ctgacctata gactgctcct ttggtccgca gataaaaaaa gaacctttca cgactcgtga
     6781 agggttcttt ttatgatttt attatatttt gtagtaacga atatcatttt cgatctttgt
     6841 aatcgaaaaa ggtacatctg aagtatattc tgcacattct ccgtgttcag gaagcgtctc
     6901 actgaaaatc gtttcatatt cgtcaacagt gatccgtgtt cgagaatcta gcatctcttg
     6961 atgagattgt gcgaagagat attcttgata gttttcttcc agataacctg taaaaaattc
     7021 acttactgca ccagaaccgt agctgaatag accgatgcga tctcctggct gtagtgattt
     7081 cgaattttcc agtagagaag ttagccccag gtataatgaa ccagtgtaaa gattaccgat
     7141 tcgtcggctg taacggatgc tttcttcata gcgagccata agacgttcct gattttcttc
     7201 gtctgtttgg tctaatacgc tttgcaatgc cttttttccc atcttagtat acggaatatg
     7261 gaaagcaatc gcctgataat cttcgagtcc tcgacccgac aattctttat gtcgattcca
     7321 aactttttgg aatgattcga tatacgtaga attagataaa ggaccatcaa caacaggaaa
     7381 ttcgctataa tctggacgcc agaaatcata gatatcttct gtcagaaata cgctgtcgtc
     7441 ttcaatcgat aaaatacgcg ggttttgagt gatcatcatc gcaacagcac cgacaccttg
     7501 cgtcacttca ccaccgcttg ccaagccgta acgagcaata tcacttgcta tgactagtac
     7561 ttttcgttct ggatgatttt tgacatattc tttcgccatg tgcaaagctg cggtgccacc
     7621 gtagcaagcc tcttttactt caaaagaacg agcaaaagat tggattttca gtaaatggtg
     7681 gataattacc gcactcgctt ttgaatgatc aatcccggat tctgttccga cgatgaccat
     7741 gtcgattagc tcacggtctt tttctgttac gattttgctg gcagcatttg ctcctagtgt
     7801 aatgatgtct tcatttgcac gattgactgc catttggtct tgaccaatcc ctatatggta
     7861 ttttgcagga tcatccccac ggctttctgc caactctgtc atatctaaat ataaattagg
     7921 aataaaaaag gaaagacgat caatccctat tttcatttca acacctcttt acttatgata
     7981 aaaaacttac tttactaagg tatcataaaa agattaaaag aaatataaaa aagagaatat
     8041 ttaaggattg ttaaaattta atcttagaaa aaaacaactg gaacaagagc tatttgtttt
     8101 tacagcaaag aatggtatat ttttgtagga ggtggcttac ttgaaagaag tcgttatgat
     8161 agatgctgca agaacgccga taggaaagta tcgcggaagt ttaagtccat ttactgcagt
     8221 tgaattaggc acacttgtga ctaaaggatt attagataaa acaaaactga aaaaagataa
     8281 aatcgatcaa gtaatattcg gaaatgtcct gcaagctggt aatggtcaaa atgttgccag
     8341 acagattgct ttgaacagcg gtctccctgt agatgtccca gcaatgacga tcaatgaagt
     8401 ttgcggatct ggtatgaaag cagtgatctt agcacgccag ctgatccaat taggtgaagc
     8461 agaacttgtg atagccggcg gaacagagag tatgtctcaa gcacctatgc tgaaaccgta
     8521 tcagtcagaa acaaatgaat atggtgaacc aatttccagt atggtcaacg acggattgac
     8581 tgacgcattt tcaaatgcac atatgggatt aaccgcagag aaggttgcaa cacaattttc
     8641 tgtgagcaga gaagaacagg atcgctatgc cttgtcgtcc cagttgaaag cagcacatgc
     8701 tgtcgaagcc ggtgtatttt ctgaggagat catcccagtc aagatttctg atgaagacgt
     8761 gttatctgag gatgaagcag ttcgtggaaa tagtacattg gaaaaactgg gcacgttacg
     8821 tacagtattc tcagaagaag gaactgtaac agcaggaaat gcttcgccat tgaatgacgg
     8881 tgcctctgtg gtgatccttg catccaaaga atacgcagaa aataataatc tgccttattt
     8941 agcaaccatc aaagaagtag cggaggtcgg tattgaccca agtatcatgg gaatcgctcc
     9001 aatcaaagcc attcaaaaat tgacagatag atcaggaatg aatttatcaa caatcgatct
     9061 ttttgagatc aatgaagcat ttgcagcttc ttctatcgta gttagccaag aactgcagtt
     9121 agatgaagaa aaggtcaata tatatggagg agcaatcgca ttaggccatc caattggtgc
     9181 aagcggtgca cgtatcttga ctacattagc ttacggattg cttcgtgaac agaagagata
     9241 cggtattgct tcattatgta ttggtggagg tttaggcttg gcagtcttgt tagaagcgaa
     9301 tatggagcaa acacataagg atgtgcaaaa aaaaaagttt tatcagctta cgccatctga
     9361 acggcgcagt caattaatag aaaaaaatgt attgacacaa gaaactgcgt tgatttttca
     9421 ggaacaaaca ctttctgaag agctctccga tcacatgatc gaaaaccaag tgagtgaagt
     9481 ggaaatccca atgggcatcg cgcagaattt tcaaatcaat ggtaagaaaa aatggattcc
     9541 gatggcaaca gaggaaccat ctgtcattgc agctgcaagt aatggtgcaa aaatctgtgg
     9601 aaatatctgc gcagaaacac ctcagcggct gatgcgaggg caaatcgttc tatcaggaaa
     9661 atcggagtat caagcagtga tcaatgcagt taatcatcga aaagaagagc tgattctttg
     9721 tgcaaatgaa agttatcctt caatcgtgaa acgcgggggc ggtgttcaag atatctctac
     9781 tcgggaattc atggggagtt tccatgcata cttatctatt gattttttag tggatgtaaa
     9841 agatgcaatg ggcgctaaca tgatcaactc gattcttgag agtgtggcaa acaagttacg
     9901 ggagtggttc cctgaagaag agattctatt cagtatttta agtaattttg ctacagaatc
     9961 attggcttct gcctgttgtg aaatcccatt cgaacgctta gggagaaaca aagaaatcgg
    10021 tgaacaaatt gccaaaaaaa tccaacaggc aggggaatat gcgaagcttg acccttaccg
    10081 tgcagcaacg cacaacaaag ggatcatgaa tggtatagaa gctgtagtgg cagctacagg
    10141 aaatgataca cgtgcggtta gcgcttcgat tcacgcctac gcggcaagaa atggattata
    10201 ccaaggatta acagactggc agatcaaagg ggataaacta gttggaaaac taacggtgcc
    10261 tttggctgtt gccacagtag gcggagcttc caatatcctg ccaaaagcaa aagcatcttt
    10321 agctatgtta gatattgatt cagccaagga actagcacaa gtaattgctg cagtagggtt
    10381 agctcaaaac ctggctgctt tgcgtgcatt agttacagaa ggaatccaaa aaggccacat
    10441 gggacttcaa gctcgttcat tagcgatctc aattggggct attggtgagg aaatcgagca
    10501 agttgcgaaa aaattacgtg aagcagaaaa gatgaaccag cagacagcta tacaaatatt
    10561 ggaaaaaatc cgggaaaaat aaaaaagcaa tatctttaga agaataaagc aagatttaca
    10621 gttattttat ttactgcaaa tcttgctttt ttctctatca gaaaatatgt ttattattag
    10681 aattttttat agttaaggtt aggcatctta agaaatcagg caactccaag atatcttcag
    10741 gtagaagaga agtcgcctaa cattgtagga tcataggtga tttgttggac aggtcaagct
    10801 gatatttgag cctgatgtta gaaggaattt ctttttactt gctgtagaaa ttattatatg
    10861 actaaaaagg ctgggatttt aaatcccagc cttttatgac aaatagaatt tttatcgatc
    10921 agtaatcgct gtcgctgcaa attgttcgat caaaggaatc aaagtcaatt tgactttgta
    10981 tttccgttcg agtgcttttt cgataacgaa ctcattttca gtagtcatag aaatagttgc
    11041 taatttacga ggttcatcag catttttttc attaataact acttcatgtt cattttgttc
    11101 tgtgtaaaat ttaggatact cagcaacggc ttttgaaaaa tcagcaaaac ttaaagcggc
    11161 attcgtatca gttgagcgtg tattttcagt tgtgtccgct tttggttttt ccgttttttc
    11221 ttctggcaca ctgactgttt cttctgtaac tggtgtcgca acagcttgcg cagttggttc
    11281 atcgtttttc aatcgttgat cattccagta agacacgatt tcaataagaa gattgtcacg
    11341 gaatcgttcg aaaatcccgt tttctcctga acgaattctc tttaatacag tattgaagtt
    11401 gtcatcgatt ggcacgttga tccgtgtatc ttcatttgtt ttcccagcta atccgatcgt
    11461 taagatttga cggtttttgg gatcaagcat gacttgtaac ggcaaaccat agcgtcgcaa
    11521 gctctcttct tctagagaac ggaataattg tcctcttaca ccatccaatg aaggacggaa
    11581 ttgatttaat aatttttgtt tctgtttttt cttcatatgt tctctccttc gctcataccc
    11641 tttcgattat aagaaaaaaa cagccaaatg aaaaggagta atgcaaaaaa acttgcgtat
    11701 acgcaaatta caacagaaaa atttgcgtat tttcccgttt tttgaaagaa aaataaaaaa
    11761 tggaacggat tatgtatata tacataatcc gttccattct ttctattttt tcggtatcaa
    11821 ggcaaaaaca ggtagttcag gtgaataaat gacttcatgt tcgtgccagg gtttgaccat
    11881 tagcgaatga tcgaaccgtt ttttcagttc ttcgatgatt tgatcatgtg tccagtttct
    11941 tgcaggaaaa tgttggattt tctctgcatc gatcaaaaag acaaaatcgg aatgaaaagt
    12001 ctgggtaact tcttccgaga gagaattcaa gcgttcgatt ggatccataa aatcaccttt
    12061 cgacttaaaa ttgggtagta tctgggtctt ttgctttgcc gactacacca tctaactgat
    12121 cgatttgttt catttcttct tctgttaatt caaaatcaaa taattcagta ttttctttga
    12181 ttctgcttgg tgtcactgac ttaggaagag gaaggaattc gtgttgcagc gaccaacgca
    12241 aagcaacttg tgcaatcgtc ttgtcatgtg cttcagcgat ttgtttcatt tcaggcacat
    12301 cgaagatttt accagtgcct aatggactat atgcttcgag gatcatatca tgtttttttg
    12361 catactcaac tacagttggc tgtaattcgc ctggtgcaag gaaaacttga ttgaccatcg
    12421 gcataatttt tgctgttttt gctagtgtat ctagatggtg gggtaagaaa ttgctcacac
    12481 cgattgcttt gattttacct gcttcataca gttcttcaaa tgctcgccat gtatctgcat
    12541 ttgcttgttc ccaattatca cgaaaagcaa cagggtttgg ccagtggatc aaaaacagat
    12601 ctaaataatc tgtttggagc ttcttcaatg attcttcaaa agaagacatc acaagttcat
    12661 agctgtggtt tgcattccat aattttgttg tcaagaatat ctcttctcta ggaattccac
    12721 tttccttaat cgcttggccg acactttctt cattcttgta tccttgggca gtatcgatat
    12781 ggcgataacc tgcagccagc gcttctttaa cagaggaaac agcgacatcc ccatcaggtg
    12841 tttgccatgt gccgaatcct actaccggga tttcgtaacc atttaataga cgataagtgc
    12901 ttgttaatga attcatactt tcagctcctt ttttattcgt tcaactataa gtgtagcgca
    12961 tttttcgaaa aaaagaatcc attttgtttc tactcttgaa atttttgttt aaaagaaaat
    13021 gattttgatt ctggtatttt tgattttttt tccgtaaact aagacagaag ggaatgagaa
    13081 aatggatatc tatttaaaaa aagcaattct gcatattatt gacagagaaa ctggttctcc
    13141 agtcttttca caaaaagagc tggatctgac aaaagaatat attcgtgatt ttcttcaaaa
    13201 gaagatccaa aaaatctctt ctgctcaaac aaaaactgga caactagcag aagaaagcat
    13261 gatcgttgaa tcacttaaaa tcgctcaaga aaattttgtg gaagcaagtg aagcaatcgt
    13321 tcagcggtgg ttcgatatct accaagaaag tgaagaagca cctagtgcag atgtatttgt
    13381 tgttttgtat gaattagata cagtgatgta cttatcttta ttgaaagtca attatcgtga
    13441 ggcttacact cactttgttg aagcagacga agcagggatc gacaaccgct tgattttgaa
    13501 tcgagcaatt ctaggggcga aaacacaaaa agcagatgaa gcattcgctg tgaatttgac
    13561 tgattggacc tacgaattaa ttgaaaaaaa atatgagttt tctggcaaaa aagagcttta
    13621 tttttctgga agagtgatcg aaagtgttcc tgcaccttct ttagaagaaa atgtaaaagt
    13681 gatccaaaaa gtagccaagc atcttggaaa aaaatttgag acagaagaat ttgatatcat
    13741 ggctgatttg aaagaagctg tctatgatac gatagaagaa aaaggtcggt tggatcatga
    13801 gatgattgcg gaaaaagtct tcaaggaaaa catcacggca aaaatggctt ttaaagaaga
    13861 agtacaagag caaggatttg tcccagaagc acctcctgta aaagaagtac aagaaatttc
    13921 tgagaaaaaa tttggaaaac aaaaattcaa gctatcaaac gggatcgaac tgatcgtacc
    13981 agtagatgta tatcgcaacc cagatttgat tgaatttgtg aataatccgg atggtacgat
    14041 atccgtgatg atcaaaaatg tggatgaagt attgaatcgt ttataaaaat gactagaaca
    14101 ttaggtgttc aagtaccagt gatcagttaa atgaattgtg tcaagagaag gatcggaaaa
    14161 gacgaatata acaaaaaaag agcgtg
//
LOCUS       DAKCAA010000062        13969 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000062 DAKCAA010000000
VERSION     DAKCAA010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.062"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(325..2322)
                     /gene="tkt"
                     /locus_tag="OUE31_002137"
     CDS             complement(325..2322)
                     /gene="tkt"
                     /locus_tag="OUE31_002137"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCU0223121.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2424..2675)
                     /locus_tag="OUE31_002138"
     CDS             complement(2424..2675)
                     /locus_tag="OUE31_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HCU0223122.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2822..3445
                     /gene="lexA"
                     /locus_tag="OUE31_002139"
     CDS             2822..3445
                     /gene="lexA"
                     /locus_tag="OUE31_002139"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HCU0223123.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3624..3842
                     /locus_tag="OUE31_002140"
     CDS             3624..3842
                     /locus_tag="OUE31_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223124.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4130..4642)
                     /locus_tag="OUE31_002141"
     CDS             complement(4130..4642)
                     /locus_tag="OUE31_002141"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HCU0223125.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="OUE31_002142"
     CDS             complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="OUE31_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HCU0223126.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7095..7538)
                     /locus_tag="OUE31_002143"
     CDS             complement(7095..7538)
                     /locus_tag="OUE31_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HCU0223127.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7539..8327)
                     /locus_tag="OUE31_002144"
     CDS             complement(7539..8327)
                     /locus_tag="OUE31_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCU0223128.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8324..9265)
                     /locus_tag="OUE31_002145"
     CDS             complement(8324..9265)
                     /locus_tag="OUE31_002145"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HCU0223129.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9442..10029)
                     /locus_tag="OUE31_002146"
     CDS             complement(9442..10029)
                     /locus_tag="OUE31_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HCU0223130.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10250..11557)
                     /gene="obgE"
                     /locus_tag="OUE31_002147"
     CDS             complement(10250..11557)
                     /gene="obgE"
                     /locus_tag="OUE31_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HCU0223131.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11851..12861
                     /gene="gap"
                     /locus_tag="OUE31_002148"
     CDS             11851..12861
                     /gene="gap"
                     /locus_tag="OUE31_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCU0223132.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12946..13881)
                     /locus_tag="OUE31_002149"
     CDS             complement(12946..13881)
                     /locus_tag="OUE31_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCU0223133.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3857 a         3130 c         2454 g         4528 t
ORIGIN      
        1 gagcaatcgc ttttttattg atcaccattt ttcttttagg tctatggtgt cgggcactgc
       61 gggtcttcag ctcttgcatt caaattcctc ctcaaaataa aaaaacttaa taaaaagttc
      121 tcttcttaaa acaaacttaa ttaattaaat tatactttta attctcaaga aacacaaact
      181 aatccgaaga attctttgtt ttgtcattta aatgtaacat agccgaaaac gaaaagtaat
      241 attgatttat tcttctaaca cataaagaac agctgtctcc aacttgcaga cagctgttct
      301 tatcagtcaa acaattgctt ggatctatga tagttgattg tacgtattca cgacattttc
      361 tactgtaaat ccaaattctt ctaaaatttt agtgccaggg gcagatgcac cgaaatgatc
      421 gattgtaatc gttgcgccct ctgttcctac gtagcgttcc caaccaaatg atgcagcagc
      481 ttcgatagcc acacgtttct tcactgattt aggaagtaca ctttctttat attcagaaga
      541 ttgtttttca aagaggtcaa agcttggcat agaaacaaca gaaacatctt tgcctttttc
      601 agccaattct ttttgagctt tcacagccaa atcaacttca gaacctgttg caatcaaaat
      661 accttctggt gtttctcctt gtgatggaga aagaacatac gcgccttttt tcaccatttc
      721 atctgctact tcttttgtag aaggcaatac tggaaggttt tgacgactca atacaaggat
      781 agtaggcgca tctgttgtct ccatcgctac tttccaagca gcacgtgttt catttccgtc
      841 tgccggacga atcacttgaa caccaggcat gcagcgaaca gatgctagtt gttcaatcgg
      901 ttcgtgcgtt ggtccgtctt ctccgacagc aaccgagtca tgtgttaaga cgtaaacaac
      961 aggagtatgt tggattgctg ctaaacgaac tgctggtctt agataatcga caaagacaaa
     1021 gaatgttcca ccgtagatac gagttccgcc atgaagttgg ataccattca tagccgaagc
     1081 cattgcaaat tcgcggacac cgaaccagat gttgcgtcct tcataatgtt caggagtgaa
     1141 atctttatct gcagccacca ttgtattatt ggaacctgac aagtccgctg aaccacccca
     1201 gaagcttggt atagctttcg ataattcttg gatgacttct ttacttgaaa cacggcttgc
     1261 ttgactgctt ccaacttcat aagttggcaa ttctgcatcc cagttttctg gtagtttgcc
     1321 atcaaaagca tcttcaaatt gttgtgctaa ttcaggataa gcttttttat aattggcaaa
     1381 catttcattc catgcatctt cagctttttg tccttcttct atcatcgttt gatggaagcg
     1441 ggcagctact tcttctggaa cagtgaaatc tggatactcc caaccataaa cttctttagc
     1501 catcttgatg ccatcttcac caataggagc accatgaaca gcagatgttc cttctttagg
     1561 agcaccatag ccgatgactg tttttacttc gatcaatgtt ggtttgtctg tttcagcttt
     1621 tgcttcttca atcgctttag agattgcttc taggtcattt ccgtctttca ctaagatatg
     1681 ttgccagcca tatgcttcat agcgagcacc aacgttttct gtgaaagctt ttgaagttgg
     1741 accgtctagt gaaatatcgt ttgaatcgta taaaacgatc aatttcccta gtttcatatg
     1801 acctgccatc gaacttgctt cttgagatac cccttccatc aagtctccgt caccgcatat
     1861 tgcatacgta tagtgatcca tcacattaaa gttttctttg ttatacgttg ctgcaaggtg
     1921 cgcttctgcc attgccatac cgacagccat tgcaatccct tgtcctaatg gccctgtagt
     1981 ggcttctaca ccatctgtgt gatgtacttc aggatgtcct ggtgttttag aatcccattg
     2041 acggaattgt ttcaaatcat cgattgtcac ttgatagcca gctaaatgaa gcaagctata
     2101 caacattgct gacccatgtc ctgccgaaag aacgaaacgg tcgcggtcag cccagttttt
     2161 tgatgtcgtt ggatttactt tcaggtgttt tgtccataac gcatatgcca taggtgctgc
     2221 gcccatcggc aatccaggat gtcctgagtt tgctttttgg actgcttcaa tacttaatgt
     2281 acgaattgtg ttaacgccaa gttggtcaat tttgtcaaac aaaataaccc ctcctattaa
     2341 tttaggtttt ttttaccttt atttcttaca ctttcattct ataagatgtc acacgaaaaa
     2401 gcaatctttt tcagtatttt ttactaaaag ttgtcatttc ggttgtgtaa gccttttttc
     2461 ttttggattt cttttaattt ttccggggtc acgtcattgc cctcaggatc gacgactttc
     2521 attccttcga tatgatgacg cataccggaa cgaaaagctt ccaaatactc tttgcgtaag
     2581 ttgatttgtt cttgttcttc ggcttttgag agaccatttt ccttcttttt acgtgcaagt
     2641 tcattgatcc tctctatttt ttcaggtgac agcatgctca gccctccttt tactctcctt
     2701 catattatat aaaaactgaa aaaaaaacaa ctagataaac taaataaaat acgaacattc
     2761 gtttgattta gcgcttttta tatggtacta tttatttatc aagtgaaaga aggtgtacct
     2821 tgtggcccga caaactgaat caagacaaat cgaagtctta cgatatatcc atgaacaagt
     2881 aacccaaaaa ggatacccgc cgactgtccg tgaaatcggg gaagctgttc agctttcttc
     2941 tacttctact gttcacggtc atcttgcacg gcttgaaaaa aaagggttta tccaaagaga
     3001 tccgacgaaa cctcgtgcaa tcgagttgac aaaacaaggt ttagaaaaga ttgggattcg
     3061 tccaacaact attccagtac ttggcgtcgt aacagctgga gaacccattt tagcagtaga
     3121 ggatgcttca gacttctttc caatccctcc taatctttct tccgaagaag gcagtctctt
     3181 tatgctgaca attcgtggag atagtatgat caatgctggg atcttggatg gtgacaacgt
     3241 gatcgttcgg aagcaagaaa ctgctcaaaa tggcgatatt gtcattgcaa tgactgccga
     3301 ggacgaagcg acttgcaaac gattctataa agaaaaaaac tttttccgtc tgcagcctga
     3361 aaacgacttg ctcgaaccaa tcatcttaga tcaagtatct atattaggac gagtagtagg
     3421 actttatcgt agtcatatct attaattgct actaataaaa gaaaactttt taaaaagagt
     3481 ttgagacgat ggtctcaaac tcttttttcg cccgggttct tcttctttca aatttttatc
     3541 acttccctct ttacaaaccg aacaaatatt cgtatactaa atatacgaac aattgttcgc
     3601 ataaattaac gaggtgagaa ttcatgaaat caatgagacg tcttggctta gtattaactg
     3661 ttttgttttt aggtattatt attggtaatt tcggcatacg tccagcttta cttgtgtttg
     3721 ttccgttatt tactttgtgg ttcatgttgt gggatgaaaa gaagtaccgt caatctgagc
     3781 ggcgcagaat tcatgaagat catttctatc atgagcccta ctacagatcc aggcaatcat
     3841 aataaggatt gactgctaat tattcaaaag acaagaagtt aaacttttac gggggtgtga
     3901 caaaaatcgg tcacatcctt ttttcgaata aacggtgttc taaagccagt ttttcggtat
     3961 taagtcaaat tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat
     4021 ttataaaaaa atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt
     4081 taaaatcgct tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca
     4141 ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga
     4201 tcaaaaatgc gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt
     4261 tgattgttcc tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa
     4321 tggcatcctt atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga
     4381 tggtttctcg aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat
     4441 aagcaacagg acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc
     4501 gtttttcttt tgcataattt acgatttgct tcgtagcttc ccgataagcg tcaccatctg
     4561 ccatcagtgg ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg
     4621 caatataatc ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg
     4681 gtaggaatat cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgccgctgg
     4741 tataatctgc tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg
     4801 ttctctattg taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt
     4861 tcagggatac gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct
     4921 tgagaatgga tcagtttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa
     4981 taggcctcat caggcgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa
     5041 acttctttca gatccgctaa atcatctgga caatccataa taactagaga gttcggtttt
     5101 cttttttcaa ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg
     5161 ataatctcag gcacgaattt caacgtagaa gaatcaaatg ctaaataaag gctaccttcc
     5221 gacgttcggc tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc
     5281 acagaaaaat cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa
     5341 agctttccta ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca
     5401 aaagcgaccg catcaagctg actcgatgca ttggaaagga caaatttcag atgctgttgg
     5461 tttgctccga ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa
     5521 ggattatccg taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact
     5581 tcatttggca gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga
     5641 tgatcgacta tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc
     5701 gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca
     5761 agcatttcaa aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct
     5821 tcttttaaag taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca
     5881 atgcccaaaa cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta
     5941 ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg
     6001 atctcattca atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac
     6061 gagacggcag gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa
     6121 aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc
     6181 tgaagtccta tccgttctga atgatgaatg gcattgattc ctaatgaaac aaggattcga
     6241 ttctcatcag tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat
     6301 tctacaggcg gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc
     6361 aaatctggaa atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct
     6421 ggtaaattct caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga
     6481 gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt
     6541 ccttcttcga tcttttcttg gtatacagat tggtttggtc catacccatg ctcaaatcga
     6601 tttggcagga atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt
     6661 gcactggtga tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt
     6721 acagcttctt ggattcggct gattgcttta tccatatcgt gcatcagata cggatcatgt
     6781 aattcttgtt cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt
     6841 tgccacagta acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag
     6901 gattcagaag gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca
     6961 ctcctaactt agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa
     7021 aaacagatca gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt
     7081 atgaaatatc cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt
     7141 tcttccggcg ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa
     7201 gcagcttcca actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct
     7261 tcaattttct tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt
     7321 tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc
     7381 agcgcagaac cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt
     7441 acaggaacat ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat
     7501 ccaagaatca cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg
     7561 ctggctaaat aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa
     7621 ataaacggtt gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc
     7681 aacttggcag gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca
     7741 gccttatcga agaaatctgt ctcgattgga cctggattca ctgtcgtaac agctacgcca
     7801 agtggtttca attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca
     7861 gaataaaccg ttgattttgc agttgccatt tttccagcca tagacgcgat attaatgata
     7921 tgaccttgtc ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct
     7981 aagatgttga cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg
     8041 aaaatcccaa aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc
     8101 ttttcatata attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc
     8161 tctttgccgc tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt
     8221 gcgcaactta taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga
     8281 ccgcctgaac tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct
     8341 cgcgaaatgg aatctcaatg ctatcaaaat ctttcatgat cgtcgtgttt tcaaacactt
     8401 cttgtgcttc tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag
     8461 taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg
     8521 aatggaaata gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca
     8581 gaatatcgct attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa
     8641 tagtcacgat tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc
     8701 catcttctag ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa
     8761 tacctaattc ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac
     8821 gataaccaaa actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat
     8881 cagtaaaaat cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg
     8941 tttgcgaaat acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct
     9001 ctaatggcgt atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa
     9061 tatgatcgcc gtgtaaatgt gtaataaaaa ttttaccgat ttttctcgga cgaatagtcg
     9121 ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct
     9181 cgtctaaaag tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac
     9241 ctgttcctaa aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt
     9301 ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa
     9361 cgttctaaag cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt
     9421 gagatcctct gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt
     9481 ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc
     9541 tttcgcatca tgcacatctt tttcgacatc ttcataatcc aagcgggtaa tttctccgcc
     9601 taattccatc attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat
     9661 cagtcctgta gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc
     9721 ttttatttct ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa
     9781 aatccctagc ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga
     9841 tttgttatta ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg
     9901 atcatggctg acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt
     9961 gatttctgaa aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg
    10021 tttgctcatt aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgta
    10081 aaataagaaa agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta
    10141 tcacagctcc tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct
    10201 cccttaaatc tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa
    10261 attcaaattc aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa
    10321 gagcttcatc cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat
    10381 gatcgaaatt cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg
    10441 catctgaatc acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag
    10501 tttcttcttc cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg
    10561 ctgtagcatt caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg
    10621 ggatgtcatc agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta
    10681 gattttccgg tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta
    10741 gcaagcgtaa gttataagta gataattctt tgttgatggc aagatagtct tcataaggat
    10801 ctcgtccttc catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat
    10861 gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca
    10921 agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttagggacga
    10981 gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag
    11041 tcgatttccc gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta
    11101 gttcgatttt tcgctcttgt cctggttcgc cgttttcagc aatttccggt gcaggattcc
    11161 gaggagaggc aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg
    11221 tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg
    11281 ttccttgtgg tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca
    11341 tcccattttc acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac
    11401 gtaacccttc atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg
    11461 gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc
    11521 cagctttcac atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt
    11581 attcatttat ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta
    11641 tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt
    11701 ttatcatttg gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa
    11761 tattctttgc gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac
    11821 agcaccccta ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt
    11881 gggcgtattg gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta
    11941 gtagcaatca acgacttaac aagtccaact atgttagcac aattattgca atttgactct
    12001 actcatggta cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc
    12061 gaagcaactc gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac
    12121 ggtgtagata tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg
    12181 catttagatg ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc
    12241 atcgtctata acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt
    12301 tcatgtacaa caaactgttt agcacctatg gcttatttct taaataatga atttggaatc
    12361 gaagttggta caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga
    12421 cctgtaaaag gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat
    12481 tctactggtg ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa
    12541 ggacacgcac aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg
    12601 aaaacaaaag taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat
    12661 ccttcattcg ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa
    12721 ggttcgatct ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt
    12781 aaaactgttg catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta
    12841 gaaaaattcg ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat
    12901 ccagtcaaag gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg
    12961 gcttaaaaat tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc
    13021 atgctcggct ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt
    13081 atctaacatt tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg
    13141 ctggtttttc ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac
    13201 ttttgtcact agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc
    13261 tagctgataa gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt
    13321 cacattatct ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac
    13381 accgtataga acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg
    13441 tacatagtct ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg
    13501 tcctcttgca tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt
    13561 ggtcatcgtt tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt
    13621 cgtttcagca ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca
    13681 atcgcttcgg ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg
    13741 tgttgtacca ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt
    13801 ataaaaataa ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag
    13861 gattttcatc caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg
    13921 aattagtata atcaaagaat ctctactatg caatgttcat ttttataac
//
LOCUS       DAKCAA010000063        13944 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000063 DAKCAA010000000
VERSION     DAKCAA010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.063"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            158..532
                     /locus_tag="OUE31_002150"
     CDS             158..532
                     /locus_tag="OUE31_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCU0223134.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(646..1275)
                     /locus_tag="OUE31_002151"
     CDS             complement(646..1275)
                     /locus_tag="OUE31_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCU0223135.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1409..1481)
                     /locus_tag="OUE31_002152"
     tRNA            complement(1409..1481)
                     /locus_tag="OUE31_002152"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1446..1448),aa:Thr,seq:ggt)
     gene            1695..1768
                     /locus_tag="OUE31_002153"
     tRNA            1695..1768
                     /locus_tag="OUE31_002153"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1729..1731,aa:Asn,seq:gtt)
     gene            complement(1906..2070)
                     /locus_tag="OUE31_002154"
     CDS             complement(1906..2070)
                     /locus_tag="OUE31_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223136.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2365..3693
                     /locus_tag="OUE31_002155"
     CDS             2365..3693
                     /locus_tag="OUE31_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HCU0223137.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3895..4728
                     /locus_tag="OUE31_002156"
     CDS             3895..4728
                     /locus_tag="OUE31_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HCU0223138.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4744..5481
                     /locus_tag="OUE31_002157"
     CDS             4744..5481
                     /locus_tag="OUE31_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HCU0223139.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5636..6604)
                     /locus_tag="OUE31_002158"
     CDS             complement(5636..6604)
                     /locus_tag="OUE31_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HCU0223140.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6836..7669
                     /locus_tag="OUE31_002159"
     CDS             6836..7669
                     /locus_tag="OUE31_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HCU0223141.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7703..8542
                     /locus_tag="OUE31_002160"
     CDS             7703..8542
                     /locus_tag="OUE31_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCU0223142.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8568..9128
                     /locus_tag="OUE31_002161"
     CDS             8568..9128
                     /locus_tag="OUE31_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCU0223143.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9327..11048
                     /locus_tag="OUE31_002162"
     CDS             9327..11048
                     /locus_tag="OUE31_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HCU0223144.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11213..12355
                     /locus_tag="OUE31_002163"
     CDS             11213..12355
                     /locus_tag="OUE31_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCU0223145.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12371..13582
                     /gene="thiI"
                     /locus_tag="OUE31_002164"
     CDS             12371..13582
                     /gene="thiI"
                     /locus_tag="OUE31_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HCU0223146.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4758 a         2303 c         2838 g         4045 t
ORIGIN      
        1 gtctagttaa ttgtagccta tccaagtcta cactctgaga tgtaagaaat atcataagat
       61 atttcttaca tctttttgtt ttgagcagga ctttagataa ttttattaat atatgctagc
      121 atgcttttgt aagaaaaaga aagagggcgt attagttatg tatcttaaaa ttacggaaca
      181 agcacaagaa agattacaaa aatatattga tgaaggcgca acagttatat tggatttaga
      241 tgatggcgtt ggggaatatt ctaaaatggg tgtttgctct ttagatacta gttttcgttt
      301 acttcttctt gataaagaac agagaaaaaa tgattataaa ctccaattag atagtgatat
      361 tggggatgtt tatataaaag attattcaaa aatgtacatg gatgaacata tgaccctttc
      421 tttagatcca cgtctaggtg tatttactct tgaaagccca agtggttctt tagacagtca
      481 tgttcaatta gtagatctac gaccagaaaa attctctgga ataaaacaat aactttctct
      541 ctattgtcca taaaactagt ctcaatcaag ctgtattgaa aaaacaagac aacattctta
      601 ccatggtaaa taaaaagacg acacattttg tcgtcttttt ttaaattaac tattttcgat
      661 aaaagatcgc atagcttgtg ccattatttc tggcttttct ctattcaatt catgttttcc
      721 gtttttaata aagagtagcc ggccattcgt tgaaagttta tataaacgtt ttgctgctgg
      781 tttattcgca tgatctttgg taccgcataa aatcaattta ggaagtcgtg atgtacgaag
      841 ctgttttttg cagtctaatg tttcaagtga acgaagtagg gtaagggttt gttttttaga
      901 tagacctaat ttttcaaata tcttagaagg tacgcagtaa aaataaatat tctggaaagt
      961 aagcaataag cgattaggag actcaaattg tggagcgact aaaacaacct tttttaaata
     1021 tggagaagga gttgcaagat agtttaaagc aataacagcg cctaaagata atccacataa
     1081 aataaaaggt tcctttatct gattcaattg tacttcgatg tatttggtta agtcgtctaa
     1141 agtagcagtg tctgtgctgt ttaaatgatt gaacaatgaa agacttttgc aagaataact
     1201 attgggtaga taagagatta catctttcca tgattgttcg tcttggccta gaccatgcaa
     1261 aaaaacaatt ttcatattgc tctccttttt atagttatca tatagacttt ctttgtacta
     1321 ttaaaatata aacattcatt tcttacgtca taaaataaaa aaacagcgca gacacattgt
     1381 taaaccaaca tgttgcactg tttaaggaag ccacttgccg ggcttgaacc ggcgacctct
     1441 tccttaccat ggaagcgctc taccagctga gctaaagcgg cattatcatt aatacaaata
     1501 ataggataac gaatattaat gtatttgtca acagaatttt ttcgaaaaaa tgtgtttctc
     1561 taataggaaa acagatttta gaaaaaataa aaataacaaa aaatgcgaac ggtttctttg
     1621 ataatataat aaaaaaattc aaaaaaagta ttgcgttatt tagaagaaat tgatattata
     1681 ttcatgtact tgattccggc atagctcagt tggtagtagc gcatgactgt taatcatgat
     1741 gtcgtaggtt cgagtcctac tgccggagta aataaagctt atgcaaagaa aaagaaatcc
     1801 aatcacttgg gtttcttttt cttttattat tatgatgaat caagctttct gtttttgtca
     1861 cgtatgttgt aatctttacg aaagagtaga gttggctact cataatcaac catacttccc
     1921 atcatcgcta aatacgaaat aaatcagcat tcctacacca atcaaagcac aagctgcacc
     1981 aagaaaaggg atgacattcc caaagttatc tgtattcata agtatgccac cacccacaaa
     2041 caaaaagccg ccagcaatca ggtttttcat tttattcatc tcctttctta cgttatagta
     2101 tttccttctt tcaatgagta ttttgaaagc tatcttattg tatgatgttc ttctaggcct
     2161 cttctttatt atacaggcca ttttcgttat ctcatagaaa tattcctttt tatctgaaaa
     2221 ctattgtata ccgtatgaca tttttcttca tgaagttgta agtatattct cattcaaatg
     2281 aaaatttcat catagaagag attgtatttc taaattctta agagtaaaat acgaagtata
     2341 acttggattt ggaaggatga ttggatgaaa gctattacgc ctgatatgac aacaaaattt
     2401 aacaaacagt ttcaagcaaa tatcaaacag caggcattgc agcgggcagt tgtgaagaac
     2461 ggaattactg cttctgctga aaatgtttca gcacatgtgg agaatacacc ggtattttct
     2521 atagatttgg ctacggggaa agtggctaat caaatgcaat cggggcgttg ctggatgttt
     2581 gctgcactga acacattccg tcataagatg ctgaatcaat tccatttaaa agagtttgaa
     2641 ttatcacaaa attacacttt tttctgggat aaatatgaaa aggcaaatta tttctatgaa
     2701 aacatcattg caacaggaaa agaggcaatc gatagccgga aagtagcttt cttactcgct
     2761 actcctcaac aagatggcgg ccaatgggat atgatcgttt cattattcca aaaatatggc
     2821 gttgtgccta aatcggtgat gccggaaagt gcgaatagtt caaattctcg agatttgaat
     2881 aactacttga acaaattact gcgtaaagat gcagtagtgt tacggaaaat ggttgctcaa
     2941 ggagaaacat tagacgctat tgaagaaaag aaagaagaaa tgctagaaag catttataac
     3001 ttcttagcta tctcattagg aacacctcca aaagaattcg attttgagta ccgcgatgaa
     3061 gaaaagaact atcatcttga ccgaggactg acaccacaaa ttttttatga taaatacatc
     3121 ggtgtaaaat tagatgatta tgttagcgtg atcaatgcac caacaaaaga caaaccattc
     3181 aatcgttctt atacagtaga gatgctagga aatgtcgttg gcgggaaaga agtcaaatat
     3241 ctgaatgttg atatggaaac tttcaaaaaa ttagcgattg ctcagcttga agaaggagaa
     3301 tctgtttggt ttggttgtga tgtaggtcaa tcttctacta gaactagtgg catcatggcc
     3361 ttagatgctt attcaatgga tgatctattt gatacggatt ttacaatgac taaagctgaa
     3421 cgtttagatt ttggagaaag tctgatgacc catgcgatgg tattgaccgg tgttgactta
     3481 gtagacgggc aatcaacaaa atggaaagtc gaaaatagct ggggcgaaaa agttggaaag
     3541 aatggcttct ttgttatgag tgatgcctgg atggacgaat atacgtacca aatcgttgta
     3601 agaaaagatt tattgacgaa agagcaatta aatgcgttca atgaagaacc aattgttcta
     3661 tctccgtggg atccaatggg tgctttagca tagacgagta tttcaatgaa gagtatgtag
     3721 taaagataaa aagagctggc ttaagccagc tctttttatc tttaaagtcc attccctgtt
     3781 ttttatggtc cctgtgctat aattctaaat aaaggataag gattggaaat aatcctttta
     3841 tcattaaaaa tatgatgacg aagtagaata aaattgggag taggggggaa agtcatggat
     3901 atccaaactg ttttatctga tctgaaatta aatggtaaag tgattccagt tgttggtggc
     3961 gatgttaatc agacctatcg tataaaaacc gaacatcgtg cttatttttt aaaaatccat
     4021 ccgaatgtaa aaaaaggatt ttttgaagca gaagtagacg gattaaaaga actgtcagca
     4081 ttcgtacgtg taccggatac gtatatgcta ggtgaaacaa gtgaaggcgc ttatttgtta
     4141 atggaatgga tcgagccggg aaaaggggat caacgagatc ttgctgcagc tttagctaat
     4201 ctccatcagc aaacagcgcc acaatttggt tttcgtaaag ataactattt gggtacactt
     4261 gttcagaaaa attcttttga agaagattgg tggacttttt tctttaaaga tcggcttgaa
     4321 tcccagattt ctttggcaga agaaacgaat cgatggaatg tacagcgtca agaaaagtat
     4381 ctgcgattta aagaacgtgt attgaaatcg gttgaaccaa aaaagatcac tccacgcctc
     4441 ttgcacggag acctgtggag tggtaatgtg ttctttgacc agcaagggca tccagttttt
     4501 gtcgacccag ctgtttctta tgggaatcgg gaacaagata ttgcaatgag ccagttattc
     4561 ggtggtttcc gaccggaatt tttagatgct tatcaaacta tatttccatt agaaaaggga
     4621 tggaaagacc gactgccgat ttaccagtta tattatcttt tggcacattt gaatatgttt
     4681 ggagaaagtt acggttccca agtagatcaa ttactagaaa atttttaaga ggagggcgtg
     4741 tttttggcaa aaaaatatac caaaaagcat gaagtttcat attatgagtg tgacatcaac
     4801 caaacgatga catttccttc gatgttagga gtagttatca aaacgtctga agatcaaagc
     4861 gaccagttgg gaagaggcag tgaattcgtc aatagctttg gacttacttg ggtcatcacg
     4921 aattattcca tggagattaa tcgtctccct agagtcggtg aagtaatctc agtaacgact
     4981 caagccatgg agtacaataa gtttttctgt tatcggaact tctggatcca tgatgaagat
     5041 gggaaagaat tagtcaaaat agaatctgtt ttcgtattga tggattttgt gaatcgaaaa
     5101 atgagcagtg ttaatgaaga gatcattgct ccttttgaga gtgagaagat caagaaaatc
     5161 aagcgtcagg aaaaaattga aaagattgat tcgggcttca tgttgccata tcgtgttcgt
     5221 ttttatgata tcgatagtaa tcagcatgtt aataatgcga tgtattttaa ttggatcatt
     5281 gacgtattag gatatgactt tttgactacg catgttccag aaaaagtaat tattcgattt
     5341 gataaagaag tagagtacgg gaatgagatc gaaagccatt ttgaacaaat ccctatcgaa
     5401 aatggtgtca aaacaaaaca tgaaatccga atgcaagaac agctgtattg tgaagcaaat
     5461 attatatgga aaaataaata aaaaagaggt tgtgacagaa gggggcaact tcaagaaata
     5521 agaagaaatt tacgaaaatt gtttctcaaa tttttgtaaa ttttcgactt agttttcgaa
     5581 gaagctattt ttgtcacagc ctctcttttt aagtttagct attagataat gatgtttagt
     5641 tttggataaa cgaaatcaat tcttcacccg acaaaccata gtttacagca atcaatagtt
     5701 ttaaacgtgc tttttgacta ttaatactgt tacagaaaat aatccccatt ttttctagtt
     5761 cttttccccc gccttcataa tcataaacag gctctgcgat tccattgaaa caacgagaaa
     5821 caagtactac agggattttt tggacaagaa gcttttccaa agcagctaag gcttgtggag
     5881 ggagattccc cgcacctaaa gcttcgatta ccaaaccgtc tactttcgta tgggcgatgg
     5941 cttccaataa gtccccttgc atcccagcat atgctttaac gatcgggata gtcccatcta
     6001 cagcggaaat gtccagtcgc tttgtttcta aaagttcctg caagaataaa attcgattct
     6061 tagttactaa gccgatggga cccaatgtag gtgttcggaa agtagcaaca tttgtggtat
     6121 gggtctttgt cacgtagcgt gcagaatgga tctcatcgtt catgaccacc aaaaccccct
     6181 tatctagcgc ttcttcacaa cttgcgacac gaatcgcact ttcaaaatta taaaggccgt
     6241 cacttccaag ttcattactt gaacgcattg ccccagtcaa aacaattggt aatttgttgc
     6301 caatcgttgt atcaagaaaa aaagcagttt cttctaatgt atctgtaccg tgtgtgatca
     6361 ccactccgga tatacctgat gcataagcgg acaagatacg ttcttttaat accaacatgt
     6421 gagaaggcat gatgtgtggt gagggaagat tgaagatatc ttcaactaat aattctacat
     6481 gcttggggat tgtgatttct gcatctaata atgggtttgc cacatcagga ctaacaccgc
     6541 ccgtgagcat gttttctttc atggcgatcg ttccgccggt gtgtagtaca agtatttttt
     6601 tcattttaca gacttcctta cgaataattt tgcatagccg ttaaatctta ttgtatacta
     6661 tataaaagag ttttgctatc agtgaagaat aacgaatagc ctaacttatc ataaaaaagc
     6721 tgaccttatt aaaatggaaa agactcaacc ttgacctcct aatacaatgg agtatctggt
     6781 tgagtttctt ttacaagaaa gcagccaagg aaatcaatca cgaaggtggc cggaaatgat
     6841 cagaatcgga ttaacatcgt ttaaagaaca tgacaaatta actggtaaaa agaataacac
     6901 tctttatgaa tatgcagggt ttctaccctt agtggaatta gatactgcct attatggaat
     6961 tccccgaaag tcctcagttg agaattggat aagtgaagta cctgaatcat ttcgctttgt
     7021 agtcaaagtc tatcaaggaa tcagcggtca aggagactgg aagccttatt atcagaccga
     7081 agaagagatg attgcgcatt ttttagatgt tatgtcgcca atggtagatg ctggaaagat
     7141 gttttgcttt ttagtccaat tcccctcatc attcaaatgt acgaaagaaa atgtccagta
     7201 cttgcgcaaa cttagaaagt ggtttgaggg ttatcctgtt tctatagaat tgcgggatta
     7261 ttcttggtac agcgatgaat ttcttgaacg tacaagaaac tttatgtcta gagccgcttt
     7321 ttctttagcc atcatcgatg agccacagtt gctgaataca acgattcctt ttgatccatt
     7381 tgtcaccaat ccgaactttg ctctttttcg attccatggt aggaatgcgc aaggatggca
     7441 agcaaatgat aaagagtggc gtaaaaaaag aacgttatat cgttattcag aaaaagaact
     7501 gcaagaacta gcacatgaag tcaaagtagt tgattctaag acaaaagagg taggtgtgat
     7561 ttttaataat aattctggtg gtgatgcggc tgaaaatgca ttagcactgc aaaaaatatt
     7621 aaatatcaag ccagatggac tcaatccaac ccaaatggat ctgttttaag ggcttatttt
     7681 attcaagaaa ggggcgaagt ctatgatcaa agctattttt tttgatattg acggaacatt
     7741 ggtcaccaat cgttcaaaag cgttggaatc aacaaaacaa gcaattgaat atgctcggaa
     7801 aaacggcatt ttatgcggtg tagcaacggg gcgcagccca gtaaagatca aagaaatcat
     7861 tgatgaattg gaattagata tgtatgtcgt gtataatggt caactggttt ttactgcaga
     7921 tcgcacgatt atcgaccacc cttttgaaca aaaagtattg gaacatattg ttgaatttgc
     7981 agatgagaac catcgacaaa tcgtttttgg tgcgagaaat cggttagatg gatcaacgac
     8041 gatgctatta ggacaatcga tttttatcaa gcgactagtc agctttttac cgcgtaaatt
     8101 cccggtacgt ctgatgaaaa aaatcctcca ggtttttagc cctcaccgac aaaaggatcg
     8161 ttatgaaacg ttagagatat taaaagaacc aatttatcaa tgtatattgc tcagtccgga
     8221 gtcagaacag aaaaagttag aacatcgctt tcccgagtgt acgtttcagc gttcaaatac
     8281 gtatactgta gatatcatcc caaaaggtgg ttcaaaatta ctaggcatcc aagctttcgc
     8341 aaatgctgtc gaaattgaaa tggaagaaat tatggcattc ggcgatcatt acaatgatat
     8401 cgagatgctg aaaggtgtag gaattggagt ggccatgggg aatgctcaga tcgaagtaaa
     8461 acatgctgca gactttgtga ctcaatcaaa tgaagaagat gggatatacg aaggactgaa
     8521 acacttcggt ctgatttatt agtcaatgaa agaaggaaaa aatcagtatg gaagcagaga
     8581 caccttttca aaaagtagaa acattccaca aaacttttga tccaagaaga ccagagatac
     8641 ccacggcttt tacagaaaat gaagctcata cacgtgctgc gttcaaaata gaagaacttg
     8701 ttgaatttgt tgcagctact tcacctaata aagaacaact gcatgaagct gttatgctgc
     8761 tgcacgaagc attagataaa gcagaagaaa aaatacttgg taaaacacag tggggaagtg
     8821 atccgctggt tgaacaagta gatgcactga cagatatcct ttactttact tatggttctt
     8881 tttcattact aggaatagtg cctgatcgaa tattcgaaat cgtccatcag gcaaatatgg
     8941 ggaaattatt tccagatgga aaacctcatt atgaccctgt aacaaataaa gtgttgaaac
     9001 ctgaaaactg gcagatggaa tatgctccag aacctaaaat cgcggcagaa atccaacgtc
     9061 agattcaaga agcgattgct aagaagaaat ccgctgatat aggcatgtgc acaaatgaaa
     9121 aagagtgatc agagtttcac tatttttgtt atctttatac gatggaaaaa caaaagattt
     9181 tcgtttaagt tagtgaatgc atgaaaatag tatgctataa tctagaatag atgtcttttg
     9241 cacgagagac gtattatttg gatttatgcc aagcagaacg ccatctgttg cataaaagat
     9301 gcatactgaa aacggaggaa ccataaatgg gaaataatgt tatcatcgga atcgtcattg
     9361 caatcattat agtcgccatt gtcgtctttt tggttagtta cttgatgaag aaaaaaaacc
     9421 aagatcgatt ggatgcctta gaaaaacgca aggaagaatt atttgacttg ccagtgattg
     9481 aagaagtcga tgatgttaaa aaaatgcatc tggttgggca aagccaaaat acctttcgtg
     9541 aatggagtca aaaatggaat gacatatcta cttcctcgtt cgctgaacta gaaagtcaaa
     9601 ttttcgaagt ggaaaacctc aatgaaagtt ttcggttctt aaaaggaaaa aaagcagttg
     9661 ttgaagcaga agctacaatg gaccaaatgg agaaacaagt gacggaaatc cgtgaaggtc
     9721 taaaggaatt gcgggaaacg gaagaacgca actcactagc tgttcagcag gcacttgacg
     9781 tctatgaaga actgaaagaa aaagtcagag aagacgagca tgaatacgga ccagctcttt
     9841 ttgaattgca aaaacagatc aaagtgatcg aaaaagaatt tacgcagttt gtgactttaa
     9901 acacttctgg agaccctgtt gaagcccgcg aggttttgga taaagcagaa aaacatacgt
     9961 atgaagtgga agctctgatg aaaaaaattc caccgctgta tgaggagctc cataccactt
    10021 tccctgaaca acttgaagaa atcagtgata cttacgagaa attgatggaa gaacaatatg
    10081 tattcccaga agaagatctt gctgaagata tcgcaaaagt aagtcgaaga attgaaaatt
    10141 cattagccaa tcttgaaaaa acagaagttg aaacggtcga atttgaaaac cgtgaaacag
    10201 ctgatttgat tgattcgtta tatgatatct tagaacggga aatggaagct cagagatatg
    10261 taaaaactaa ccaatcaacg attgcagagt atatcaaaca tacaacaaag aataaccgtc
    10321 aattattgat tgagctggat cacacatctc aaagctatac attgaaccac aatgaaattg
    10381 gccgtgtacg aggtttccaa accgaagtgg aagaaatgga acgtcaaaat gaacagatga
    10441 ttccacagat ccgtcaacac gaaattcctt attcagaagt gcgcacgttc tataaaacag
    10501 tcttcaaagt cttagaagat atcgaaaagc aacaagtaga gatcgacgac tcattacatg
    10561 aattgagaaa aggcgaaaaa gaagcgcaag aaaagatcga tacattcgaa ttcaaattgc
    10621 gcagtttgaa acgttttgta gaaaaacaac gtttgcctgg cttgccgaat gattacctag
    10681 aattcttttt tgttgctact gaccgtattg aagaactaag tgttgtcttg aataaaattc
    10741 gagtaaacat ggaagaggtc aatcgtttag ttgctctatg tgaagaagat ctagaattat
    10801 tagataagaa gacacatgat ttagtagatg cagcagcatt aacggagcaa atgctccaat
    10861 atgcaaatcg ttatcgtcat acacacgaag aagtgagaga agcaattgat aaaagctact
    10921 atttattcaa taaagaatat cactatcaag aagcattaga cgaaatcggt acagcattag
    10981 agcgagtaga acctggtgct ttcaaacgca tcgaagattt ttattttaat catccagact
    11041 tagtataaag caaaaaagtt agtaaaccag caagagcaag acggattatt gtcttgttct
    11101 tgtctttttt tgtatatttg aaaattgaaa caagtgaaaa tttcacctgc tcttgaaagc
    11161 accttggaca accgttataa tagaaaagaa tttcaaaaaa gaggggtttc ttatgatata
    11221 ttttgataac agtgcaacaa ccccaatctt tccgcaaagc ttagatgcat atgtaaaaac
    11281 cagtcagcgg attattggga atccatcaag cttgcatgat ttaggcaatc aagctaaccg
    11341 gttgttgcag caagcaagaa agcagatcgc tgatttgatc catgtagaac cagaagaaat
    11401 ctattttact tcaggcggaa cagaaggaga taactgggta ttaaaaggaa cgatgatcga
    11461 aaaaagagaa tatgggaatc atatgatcat ttcaggagtc gaacatccgg ccgtcagcga
    11521 gacagcagaa caattaaaag aattaggaat cgaagtaagt atcgccccag tggataaacg
    11581 cggatttgta cgtgtcgacg aattgaaaga attaataaga aaagagacag tattagtctc
    11641 tgttatggct gtgaataatg aagtaggatc gattcagccc atccaggaaa tcagtgatct
    11701 tttggatgat tttcctaaaa ttcatttcca tgtagatgct gttcaggcga ttggaaaagt
    11761 accattctcg caatggttga cagaaagagt tgattttgca acattttcag ctcataaatt
    11821 ccatggccca cggggaactg gtttcattta ttggaaaaag ggtcgtcgtt tagcaccatt
    11881 actgacaggt ggagggcaag aaagaaatca gcgaagtggg acagaaaatg ttccaggtat
    11941 tgtggctatg gttaaagctt tacgtttatc attagagata aaggaacaaa aacctgagca
    12001 gacacaacgc ttaaaagtag ctctaatcaa tgcgttgaag acgtatgaga aagtgacgat
    12061 tttttcagaa ggaactgact atgcaccgca tattttatgt tttgctctaa aaggaattcg
    12121 cggcgaagtt ctcgtccatg ccttagaaga aaaacaaata tttgtttcta ctactagtgc
    12181 ctgctcctca cgtaaacata tggcaagcag tacattgcac gcaatgcatg taccaaatga
    12241 tctggctaca tctgctgttc gaatcagctt agatgaaaac aattcgcttg cagaagtcga
    12301 gcaatttatg attattttca agcagcttta taagaaattt tctgcaatca attaaaagag
    12361 gagtgttctt gtgaaataca gtgaaattat ggtccgttat ggggaacttt cgacaaaagg
    12421 aaagaatcga aaaagcttta tcatgcaact agcacaaaat gtcagacaag ctttgaaaga
    12481 ctttccagaa atcaaaatcc atgctgatcg ggaccggatg catcttttat tgaatggcgc
    12541 agacgggcag ctagttattc caaaactagc aaaaatattt gggatccaaa atttctctcc
    12601 aagtattcgt gtagaaaaag atgtcgaagt tttgaaacaa gctgttcaag acatcatgaa
    12661 agaaatttat actgggaaag aaacatttaa aattatcgct aaaagaagcg atcaccaatt
    12721 tgaattgaca agtaatgaat tgaatcaaac attaggtaat gctgtttttg atattttccc
    12781 gcatatccaa gttcaaatgc gtcaaccaga tattccatta cgtgtagaga ttcggcgtga
    12841 tggcgcttat ctatcgtatg aaacgatcaa gggagctgga ggattgcccg taggaacaag
    12901 cggaaaagga atgcttatgc tttctggggg gattgattct cctgtagcag ggtactttgc
    12961 catgaagcgg ggagtggaaa ttgaagctgt tcattttgct agtccgccgt atacaagtga
    13021 acaagcactg caaaaagcaa aagatctaac agccaaacta gcaccttatg tgggaacgat
    13081 ccattttatc gaagtgccat ttaccgagat tcaagaagaa atcaaaaagt cagtgccaca
    13141 aggatattgg atgacaatta ctcgtcgaat gatgttgcgt ttgaccgatg aaattcgccg
    13201 tattcgtcat ggtttagtca ttttgaatgg tgaatcatta ggtcaagtgg cttcacaaac
    13261 tttgcaaagt atggtggcta tcaatgaagt aacgaatacg ccaatcattc ggcctgtagc
    13321 gacaatggat aaacttgaaa tcattgaagt agcagaacag atcgatacat ttaatctttc
    13381 tatccagcct tttgaagatt gctgtacgat ttttgctcct ccacagccaa aaacacgccc
    13441 tcaactggaa aaggtccatc aatatgaaga gcgtttagca atagatgaaa tgatccaacg
    13501 agcactagct ggcttgaaga tggaagagat acaagcagaa tcgtctaatg aaaaaactga
    13561 agaattttca gaattgctat aagaggttat gaaaatagtg ttttgaccag agtattagag
    13621 aaacaaaacg aaaaaatagc tccatgtatt ttaccgtttt tgaactaatg tcgaagatta
    13681 gctgattgaa taccatttat caagaagtta tggaaaagcc ggttcttttt tactaactga
    13741 aaaataaaat tttatttaga gatcaagcta cagttgataa atgatataaa aaagagaatt
    13801 tcccatgaaa tagcgaggtt gtgacagaag tgggcagctt caagaaataa gaaggaattt
    13861 acgaaaattg cttttcaaat ttttgtgaaa tttcggctta tttttcgaag aagttacttc
    13921 tggaacaccg tgtatcagag gttg
//
LOCUS       DAKCAA010000064        13877 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000064 DAKCAA010000000
VERSION     DAKCAA010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.064"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            488..1351
                     /locus_tag="OUE31_002165"
     CDS             488..1351
                     /locus_tag="OUE31_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCU0223147.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1480..3102)
                     /locus_tag="OUE31_002166"
     CDS             complement(1480..3102)
                     /locus_tag="OUE31_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0223148.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3351..3872
                     /locus_tag="OUE31_002167"
     CDS             3351..3872
                     /locus_tag="OUE31_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCU0223149.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4058..5788)
                     /gene="spxB"
                     /locus_tag="OUE31_002168"
     CDS             complement(4058..5788)
                     /gene="spxB"
                     /locus_tag="OUE31_002168"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HCU0223150.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5953..6771
                     /locus_tag="OUE31_002169"
     CDS             5953..6771
                     /locus_tag="OUE31_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HCU0223151.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6874..7071)
                     /locus_tag="OUE31_002170"
     CDS             complement(6874..7071)
                     /locus_tag="OUE31_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223152.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7240..7818
                     /locus_tag="OUE31_002171"
     CDS             7240..7818
                     /locus_tag="OUE31_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCU0223153.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7913..8050
                     /locus_tag="OUE31_002172"
     CDS             7913..8050
                     /locus_tag="OUE31_002172"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223154.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8863..9366)
                     /locus_tag="OUE31_002173"
     CDS             complement(8863..9366)
                     /locus_tag="OUE31_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCU0223155.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9725..10750
                     /locus_tag="OUE31_002174"
     CDS             9725..10750
                     /locus_tag="OUE31_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCU0223156.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11121..11999
                     /locus_tag="OUE31_002175"
     CDS             11121..11999
                     /locus_tag="OUE31_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HCU0223157.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12475..12591
                     /locus_tag="OUE31_002176"
     CDS             12475..12591
                     /locus_tag="OUE31_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCU0223158.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13519..13857
                     /locus_tag="OUE31_002177"
     CDS             13519..13857
                     /locus_tag="OUE31_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223159.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
BASE COUNT         4382 a         2343 c         2640 g         4512 t
ORIGIN      
        1 ttcacaacct ctccactaaa cggtgttctc ctgccaactc ctcggtcaca agtcacaata
       61 ttcaacaaac atgagaagct gttttttgaa attgttcctt gtgactcgga gctaaacggc
      121 aggctcacaa cctcttggta aacggtgttc aatcagctga ccctcggtat tagctcaaaa
      181 aacggcaaaa tatgaggaac tattttttcc gtttttttct ctaatactca ggtcaaaacg
      241 ctgatttcac aacctctgat tcacggtgtt ccagaagtag cttctacgga aataagccga
      301 aatttcacaa aaatttgaga agcaattttc gtaaattcct tcttatttct tgaagctgac
      361 cacttctgtc acaacctctt attttgatta gaacttgcga aaataaaccg gttaaagtgt
      421 gtctagcgca agagatttgc tataatagac gataagggta aaatgtaacg agaaggggtt
      481 gaaaaatgtg tatcaaattg taacagattc ttgttgtgat ctgccatacc atgtattagc
      541 aaaagaaaaa gttgattttt tatcaatgaa tctccaattg aatgatcaag agttagtaga
      601 tgacctcgga aagacattca attatgaccg ctacatgaat cagctgaaaa atggtgcgat
      661 gcctacgaca tcacaaatca atgttggccg atatttagaa tttttccgtt cttatgcgga
      721 aaaacagatt cctgttttat atgtggcttt ttccagtgga ttaagcggct cttacagtag
      781 tgcgcttcaa gcggttgaat tgctgaagga agaatatgaa gaccctgaga tctatgtttt
      841 tgatacaaaa gctgcaagta ttggggaagg gcttttagta ttggaagctg taagattgaa
      901 aaaagaaggt aaaagcatcg aagaaaccct agagtggctg gaaagtaatt atttgaaagt
      961 ccattcatgg gtaacagtag acgatctgaa atatctagaa cgaggcggta ggatttccaa
     1021 agcaagtgct actcttggca gtctattgag tgtaaagcct attattacgg tggataaaga
     1081 aggaaggctg acgaatgttg acaaagttcg aggaagaaac aagtcgatcc agacaatcgt
     1141 caatgagacg gtaaaaacaa tcgttgcacc acttgatcaa atcgtttatg tggcttacgc
     1201 tggggatcta gagagcgcgg agaaggcaaa acggcttttg gaagagcaga taaagatgaa
     1261 agatgtgaag ctttatccct taggaccaac gatcgccagt cacacaggct atggctgtat
     1321 cgcgattttt tcgatgggaa tcagtcgata aaagcagtaa ctcattctgt aaaaaagccc
     1381 agaaattgat tgtaacaaaa acagcgactc ttaaaagata gatgagcatc ctatctctta
     1441 gaggtcgctg tttttttatt ttttaagcta aataggccat tatgcccata actcgttcaa
     1501 ttgtttttga atatctgcat tttccaaaaa ttcatcatat gtcgtatcag ctcgatcgat
     1561 cacaccttta tccgaaacgg caatgatgcg gtttgccaat gtttggataa attgatggtc
     1621 atgtgacgca aataagattg agccagtaaa tgccatcaag ccgtcattca atgctgtgat
     1681 tgattctaag tctaaatggt tcgttggatc atctaataca agtacgttag ctttcgaaag
     1741 catcattttt gaaagcatgc aacggacttt ctctccacca gataaaacat tcactggttt
     1801 caatacttct tcaccagaaa acaacattct tcctaagaag cttcttaaga aggtgttatc
     1861 atcttcttct ttacttgcat attgacgcaa ccagtctaaa atcgttagat cagtatcgaa
     1921 ttctttcgtt gtatcctttg gtaaataaga attacttgtt gtcacacccc aacgtactgt
     1981 tccagtatct ggcgtaattt cacccatgat aactttgaat agcgttgttg ttgttatatc
     2041 attttctgcg acgaaagcga ccttgtcttc tttgctcaaa ttaaaagata tatcatctaa
     2101 aattttcttt ccatcaatcg ttacacttac attttctacc tgcaataagt cgtttccaat
     2161 ctcacgttca ggtttgaatc caacgaatgg ataacgtctg gaagaaggtt ggatatcgtc
     2221 taaagtaatt ttttcaagca tttttttacg tgaagttgct tgttttgatt ttgatgcatt
     2281 cgcactaaag cgggcaataa attcttggag ttctttgatt tgttcttctt ttttggcatt
     2341 tgcgtttgct tgaagtttag ccgctagttg actagattcc aaccaaaaat cataatttcc
     2401 tacataaagt ttgattttac caaaatctag atccgccata tgtgtacata ctttgttcaa
     2461 aaagtgacgg tcatgggata caacgatcac agtattttca aaattgatca aaaattcttc
     2521 cagccaattg atcgattgga tatccagacc gtttgttggt tcgtctagca aaagaacatc
     2581 aggtttacca aatagtgttt gtgctaataa cacttttacc ttttgtccac cagttaattc
     2641 actcatttgc tgatggtgca attcttcagg gatgttcaga ccttgcagta aaacagctgc
     2701 ttctggttca gcttcccatc cattaagctc agcaaattct ccttctaatt cagctgctcg
     2761 aataccatct tcgtcagtga aatcctcttt catgtaaatc gcatcttttt ctttcagcac
     2821 ttcatacaga cgcttgtgtc ccatgatgac tgtttcaagt acagtatagt cttcatagtc
     2881 gtaatggttc tgtttcaata cggccatccg ttcatctggt cccatagtaa cggaacctgt
     2941 ggaaggctgc agatcccctg ataacacttt aaggaacgtt gatttacctg caccatttgc
     3001 accaatcaag ccatagcagt ttccgggggt aaatttaata ttcacatcat caaatagttt
     3061 gcggtctgaa aagtgcaaac tcacatcatt tacagtaatc aatttttttc ctcactttta
     3121 tcattattag ttttgacaag tcttatagaa ttatataggg gaaaggtaaa agattcaagg
     3181 caatcgaaca ttctttgtgt ttcacgtgaa acagaatgaa aaaaataaaa ataaaagcgg
     3241 agcgaaaata gctactatag gatttattag tttgcaacag cataattttt gacgttattt
     3301 ataagaggga gtactataaa actgtaaaag aaatgaaaga aggattgaaa atggatgaaa
     3361 aaagaaccat cgactggggc tcattgattt tgggaatttt atttgtactt gtctcattgt
     3421 tatcatttca agaccctgtc ggaaatttag ttgcaattgt agtagtcttt gcgatttttg
     3481 cctttattaa agggatattt gaactgtttg tacggaacag attaaaagag ctaacaggat
     3541 ataaaggaaa gatgccctta ataatcggga tcatcgatat tctagttggc gtctttttct
     3601 tattcaatat tggtgcagga gtcgcagcat tgccttttgt ttttgcagta tggtttattg
     3661 ctgattcagt tttagcgtta tttactgctg acttggcaag aggagtaagt gaaggatatt
     3721 attggtttac gatcatcgtc aatattttag gaattttatt aggaattttc ttattgttta
     3781 atccaatttc ttctgcgttg acattaagct ttttagttgg attctatttt atgttatttg
     3841 gtatcacaca tatcgtctat gcatttagat aagtaaaatc aaacaaataa aaaagccggc
     3901 ttccgattac agttttactg ttgtaattgg aagccggctt ttttatcatg gacaaatatg
     3961 cacgaggtga tttttaggtg tcgagacaaa tttatgcaaa aatgtgagaa gctatataca
     4021 caaattttat cttaatactc gaagcatagc gcagttgtca caacctcttt tcatataatt
     4081 cattcaatac tggcaaatca tggacttcat atttttcttt gaatgcttgg atttcttctt
     4141 cagaatattt tcttggatct aaatgcagat cttctactgg caatgggcgc ttgttattga
     4201 tcttcacatc gattactaca ggacgatctg attttgcagc tgcatcaaag gcaaatcgaa
     4261 gttgcgagta ttctgtgact gtaaagctat ttgccccgag cgcttctcca actttaccga
     4321 aatctgcatc ttctaaaaat acaccaaatt tcttttgttc cgtatcttct tgttctgctt
     4381 cgatgaaacc aaaagaatca ttcgaaaaga caacattaat aattggaagc tgatatttga
     4441 cttgtgtaat gatatcttgc atgaccatag caaacccgcc atcaccactt aaggtaaata
     4501 cttgtttttc tgggtagctt agttgtgcgg caattcctcc tggcacacca ttacccatag
     4561 ttgcgaacca tccagatgtc gtatgttttt gtttaccgtt catattcaat aaacgaatag
     4621 aatggatagt cgtgttaccg acatctgtga cgaaaatcgc atcgtcttca gcaatacgat
     4681 tgatttcttt atagacagcc tctggacgaa tcggttcttc ctctcgatct tcaaaagatt
     4741 tcaaccaatt tacccatttt tctttatttt cttgatttgc taggtaccag ctatcagcag
     4801 ggcgagcatc ccctaactcg acaagtcttt gcaaagctgt gtttgcatca ccgaggatcg
     4861 acaaagatgt ttcatggcgt cgtccaaatt ttgacgcatc gatatcgatt tggataaatt
     4921 cagcagttgg attaaaaaat gcacgtccaa atgggaagtc gctaccgaca aataagatca
     4981 gatcggcttc tgccaatgct tcatttccgg gtttagtagc gacacgtcca gcaaaaccaa
     5041 gaaagttttc ataatcatca ggaataattc cttttgctag aacggaagcg acaacaggaa
     5101 ctgaaaaatg ttctgagaat tctttgattt gcggaaatcc gtttcgcgtt ccttgaccaa
     5161 cataaagaac tggttttttt gctttttcaa gataaggcaa agcagctagc aaatcttttt
     5221 cttctggtaa tatcacactt gttttgtgag tgtgagcggt ggagaaaggt tgttcgtcaa
     5281 tttcttcaaa accaagatca acagggatag tcacgatagc cacgccttta tgctcatagg
     5341 cggctttaat ggcttcatct actacatgcg gaagactttg tggtgtcatg actgtacgat
     5401 tgtatacgct aacatctgcg aaaataggat tttcatttag ttcctggaaa gagttatagt
     5461 tcatggatgt agaagcaact tgtcctaaga acgctactag aggcacatgg tccatctgtg
     5521 catcatacaa accattgatc aaatgtgtcg caccaggtcc tgcagagccg aagacagcgc
     5581 cgactttccc cgttaatttt gcatctgcag cggctgcgag tgcgccgact tcttcatgac
     5641 gaacttgaat gtagttgatt tcggtttttt cttgatatag cgcatccata attgaattga
     5701 aagatcctcc gggaatgccg taaatatggt cgatacccca gctttcaaga acttttacca
     5761 ttgcgattcc tgcattgatt tttgacatgg tgtttcactc ctttagcaat gatgatacat
     5821 aaattttttg tatctagagt atagaacttt ttatcgaaaa tcccaactaa ttcgtctttt
     5881 cacaaaaatg tagtcatgtt tttgggaata tgctagagta gtacatagat agattcaaga
     5941 gaggggaatg gcatggttga atggctattg agacttgaac cttggcagca agcacttgct
     6001 gggacagctt ttacttattt tatgacagct cttggtgccg ggttggtttt tttctttaaa
     6061 gaaatcaaaa aagaagtgct aaacttgatg ttaggatttg cttctggtgt catgattgct
     6121 gcaagttttt ggtctttgtt agatccggct attacaaaag cagaagaaaa tggagatatt
     6181 gcttggctag ttgtaagtat tgggtttggt ttaggcggtg tgtttttata tatggcagat
     6241 aaaacactgc cccatatgca ttttggacca caacatgaag cagaaggatt gcctacccat
     6301 ttaaaacgga cgatcttgct tgttttttct attacattgc ataacattcc tgaaggttta
     6361 gccgtggggg tagcattcgg tgcagcagca actgcggata atccgacagc cgctatatta
     6421 gccgctgttt cggtggcgct aggtattggt atccaaaact tcccagaagg agcagctgta
     6481 tcaatcccgt tgcgacaaga aggtctgagt cgtaaaaagg cctttgttta cggacaagct
     6541 tctggaatcg ttgaaccaat tgctggagtg attggagcgc tactagtaac gaaagtggag
     6601 ctgctgcttc cttatgcact tgcttttgcc gcaggagcaa tgatttatgt cgtggtggaa
     6661 gaattgatcc ctgaagcaca gcagacattg tccagcaaac gtcattttgc agtttttggc
     6721 gtcatgagtg gatttatcat tatgatgatt ttggatgtgg cattaggata aataaaaaaa
     6781 atatatatga tatatcaaat agggccgcga acttatatcg cgaccctatt tttttagtaa
     6841 gttatatcat aatgaagtga atggtatcat acattaataa tagttttttc tatgtgtatt
     6901 tcctttgatc cagcgaacaa gccagatgat aagtgcgatt gggattagaa ctttgaccgc
     6961 aaaccataaa agcccgctta ggacactgac aaaaagactg atgacgaagc tagctgcaat
     7021 tagcactaaa agaaccatga agatatttaa gaacatattt ttttgacgca tacaaaaccc
     7081 tcctcttgtt cattctttac tatagaaaaa gtataacagg gattgtttaa aaacacctcc
     7141 aactgaagac tgatttttac ttcatctact taaatgatca aacaattgct ttttctctgg
     7201 tttatcatct aaaatagagc ggaaaaggag gagaatatca tgcctaaaaa tcgtcttgaa
     7261 gcatttacag atgctgtaat cgcgattatc atgactattt tagttttaga acttcatgaa
     7321 cctaacggag acacgtggga ggcgctcgct gcattaggtt accgattttt tatctatatt
     7381 gtcagtttta tcattttagc gatttattgg aacaatcatc atcatttatt tcaagttgta
     7441 cataagataa atggacgggt cttatgggcg aacagtttct ttgtttttgc gctttcgctt
     7501 tttccgtttg caacttcatg gatcagtgag tacatcaata gcctggctcc agaaatgact
     7561 tatggttttg ttaccttgac cgctaatatt gcgtattata tcttggcaaa agaacttgtc
     7621 aaagcaaata aaggccacga gaaagcattg aaggcgatgt tgaataatta caagaaatcg
     7681 tatctatcga ttggtttgaa tgtgttagga attgtcttag ggtatttagt agcgccagta
     7741 gccgtgctga tcgcaaacat cgtgattcta gctgcttgga tcatcccaag tcgtaccatc
     7801 gaatcacaat atcggtaaaa tgatccgtgt ttaaaattta agagaaaaat atagaaaaaa
     7861 taaataaacg atcaaatatc cgagtgatac tagtattcaa agagggatgc agatggatca
     7921 aaaaagaatt catgtaggac tgattactag ttttgtcacg atgcttattt atttggatca
     7981 aggtcatttg acttggacag tagttggtgt cgtaggattt ttgacattat tcacagcaat
     8041 aaaaaaataa acatctttat gtaatctgat gttctatcta tttaagaaaa gcatgtttac
     8101 agcagtatga ttctgttgta aacgtgtttt tatttgtgga aaatttaatt tttagaaaag
     8161 tgtatcgaaa aatagatagt tagtttttcc acagtggata acttcgtaag agataaaaat
     8221 aaaaaattag tcaaagaagg gcgtatagat ttcttttgat aggagatata caacagaaat
     8281 gaataaatat taacgtgttt tcaaacagta taaaacggtg tggtttttgg aataaaaaaa
     8341 taacatatct cattttacgc ttttgttatt ttatacttaa aaaataacga cacagaaaat
     8401 accgtgtctc agatttctct actacttcta aaaactactg tttttttcct ttgaaatgcc
     8461 ttcaaaaagt aggatcaggc agaatatact ggcagaatca aggagaaggg agcctaaata
     8521 aggagaaaaa ccatagaaaa tataaagtaa ttacttataa aacaagcttt ttatagaaaa
     8581 ataatatacc tgagtagggt ataaattaag acggaattcc tttctagatt gagatattga
     8641 ctaggaagaa tgttaagatt ttaagccttt aagctaaaaa aaaacccttt ttgttaaata
     8701 aggggaatat agcctgtcag tttcaaactg caagtcgtcc tgctgcaata atatagtaga
     8761 ttagagatga aaatagattt ttttaaacca atgactgaat aaaaagaccg tcatagatac
     8821 acattggaat gtgtctatta cggtcttttt ttacgaacga ttttattgaa gacggacagt
     8881 tcgggtcaaa aataaaaaag ctacgatcag aaataagaat aaaatgtatc ccaaaataat
     8941 ggctagacgg tctaacttat ttgtcgatag atgtttgttt agaagttgat aggcccataa
     9001 acctatcagt cctcctgttg tattagttat caaatcagtg atgtccgcta cgccaatacc
     9061 gaataggaat tgaatcaatt ctgccaagaa gcttacaagg aaaataatcc ctaatttttt
     9121 agaaaaagaa agtctcttga aattgacatt caaaagcacc ccaaaaggaa aaaagacaat
     9181 caagttataa gtggtctcac gtaataccgt cgtattttca aaagaaaaag tagaaaaagg
     9241 gacgagattg acattgctgt aagaataagt gagaaattgt ggaagattaa atgatagctt
     9301 gaataaaatc aaccataata gaaagaataa ataaatccct aataaaaatt ttgatacata
     9361 ccgcatagac atctcctcca tttaaaaagt ataccatcga aaaccgctga aaaatcataa
     9421 aaaagtatga agtttaagga ccaacgtagt tatcgtacga aaattagaag cttttttttg
     9481 ttgggaatcc ggtttcttta acaaagctaa gatagcgagt tgcttggaaa agttgctatc
     9541 ttttttctgt caaaacgact cggaatgttc gttttttgtt ctaatttctc caagttgttt
     9601 actttttgat actaagttta tgaaaaatca agaaatagtt gttatactag gtaatgctga
     9661 caaacgggat tggcatttca tcttggttca gctttttttc caattactag gaaggaggga
     9721 tagattgttc aagacttatt ttcgtttcaa taaaatacaa gataatcctt ttcgtatcat
     9781 gaatctgatg ctacttatct ttattgtatt atggttaggt tacataaatc atgatttttt
     9841 gatttcaagt ttttcatcat tagggatctt tacttttttc tattatcaaa acataccgat
     9901 gaaatatttg ctgaaacgta tgtttctgat cggttgcgga ctgttggttg ctttcgtttt
     9961 ggggatctta tcgacttatg ttttatggct tgaaccattt gccgtagctt tggttgcttt
    10021 ttccagcaga ttcgtgttgc gattattcca tatttctaaa ccaggtggct tgttttttgc
    10081 gatgctttct gccatgggaa cgagcatgca gctgccaatc gctcaattac cgatcgtctc
    10141 actttatttt tttatgggtg tcgtttttgc cctgattgcg gcagtgatta caaaattact
    10201 ggattcacgg cctgagcaga caattgaaaa agcaacttta aaagaaagat ttcacgaaga
    10261 gcctttagtg atcattgatt ctgttttcta cagcgctgcc ttatttcttt ccgtttatgt
    10321 cagtcacggc ttgaatctgc ataatcctta ttggttgacc ttgtcatgtg catcgatttt
    10381 gctagcagaa aacttggatg cgatgaagca tcgacaagtc caatatctga ttggatcgat
    10441 gggtgggtta tgtgtgtcgg cattcttgtc atttgtgccg tttacgcagt tgcagaccat
    10501 ttttctgatc acttttctat atggaatcgc acaatttcta gttgctagaa attatgcagt
    10561 tgctaatatt tttcttaatc cgatggcgtt gatgctatct acacttattc gtggagcata
    10621 cttgatttct ttgatcgaat atcgtttttt agggatcgtc ataggaagtt tcatcggttt
    10681 aggtgttgcg tgggtaatga cggttggttt gcaacattat ttaacggttg ttcgtcaaaa
    10741 attagaatag aaggacaaat atatgtgcca aaagaggtta tgacaagatt tttgtcacaa
    10801 cctctaattc aaggtgttca aaagccagat tctcagcatt aagtcaaatt cacacaaaaa
    10861 tgtggaaagg aactttcaaa aaaattttat atttattcta tcaaaaaatt ttatatttat
    10921 tctatcaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10981 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    11041 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11101 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11161 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11221 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11281 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11341 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11401 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11461 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11521 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11581 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11641 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11701 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11761 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11821 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11881 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11941 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    12001 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12061 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12121 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12181 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12241 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12301 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12361 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12421 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12481 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12541 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12601 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12661 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12721 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12781 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12841 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12901 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12961 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    13021 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13081 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13141 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13201 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13261 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13321 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13381 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13441 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13501 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13561 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13621 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13681 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13741 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13801 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13861 ctagtgaaat actttat
//
LOCUS       DAKCAA010000065        13705 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000065 DAKCAA010000000
VERSION     DAKCAA010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.065"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..902)
                     /locus_tag="OUE31_002178"
     CDS             complement(<1..902)
                     /locus_tag="OUE31_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HCU0223160.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(926..970)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1185..2153
                     /locus_tag="OUE31_002179"
     CDS             1185..2153
                     /locus_tag="OUE31_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCU0223161.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2266..2544
                     /locus_tag="OUE31_002180"
     CDS             2266..2544
                     /locus_tag="OUE31_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCU0223162.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2662..2898
                     /gene="secG"
                     /locus_tag="OUE31_002181"
     CDS             2662..2898
                     /gene="secG"
                     /locus_tag="OUE31_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HCU0223163.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3001..3756
                     /locus_tag="OUE31_002182"
     CDS             3001..3756
                     /locus_tag="OUE31_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCU0223164.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3759..6116
                     /gene="rnr"
                     /locus_tag="OUE31_002183"
     CDS             3759..6116
                     /gene="rnr"
                     /locus_tag="OUE31_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HCU0223165.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKFGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6138..6602
                     /gene="smpB"
                     /locus_tag="OUE31_002184"
     CDS             6138..6602
                     /gene="smpB"
                     /locus_tag="OUE31_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HCU0223166.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6904..7623
                     /gene="atpB"
                     /locus_tag="OUE31_002185"
     CDS             6904..7623
                     /gene="atpB"
                     /locus_tag="OUE31_002185"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HCU0223167.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7676..7891
                     /gene="atpE"
                     /locus_tag="OUE31_002186"
     CDS             7676..7891
                     /gene="atpE"
                     /locus_tag="OUE31_002186"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HCU0223168.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7982..8506
                     /gene="atpF"
                     /locus_tag="OUE31_002187"
     CDS             7982..8506
                     /gene="atpF"
                     /locus_tag="OUE31_002187"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HCU0223169.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8493..9035
                     /locus_tag="OUE31_002188"
     CDS             8493..9035
                     /locus_tag="OUE31_002188"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HCU0223170.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9058..10614
                     /locus_tag="OUE31_002189"
     CDS             9058..10614
                     /locus_tag="OUE31_002189"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HCU0223171.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            10628..11530
                     /locus_tag="OUE31_002190"
     CDS             10628..11530
                     /locus_tag="OUE31_002190"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HCU0223172.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11553..12959
                     /gene="atpD"
                     /locus_tag="OUE31_002191"
     CDS             11553..12959
                     /gene="atpD"
                     /locus_tag="OUE31_002191"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HCU0223173.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12973..13395
                     /locus_tag="OUE31_002192"
     CDS             12973..13395
                     /locus_tag="OUE31_002192"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HCU0223174.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4530 a         2452 c         2988 g         3735 t
ORIGIN      
        1 ctttcggaaa aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc
       61 caaaattcat aacgatcaac caatgtttgt ccacgactta ttccctgagt ttccacagcg
      121 gtgaagcttt tgaaaccttc acagatggcc ccctcgatga aataagcaac agctaacgga
      181 tcattgatga cacatcctaa aattctttct tgtttccagt ggaagtcaaa ataaaaacga
      241 gtgatcgctt ttaaatactc tccctcttca ggattcattt gacagcagta ttcgaggata
      301 gtcggtgtca agacgatttc tcttgtcaca tctaacccaa ccatttctat cgtttgtttg
      361 agattctcga atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact
      421 ggcgaacagt taccatggct tttgtaagtt ccacccatcg agacaaaacg atccatatgt
      481 ttcccaatat ttgggttgac tttcaaagca aaagcgatat tggtcaaagg acccaaagca
      541 atgactgatg tatttgtctt ttctttgaaa taatcagcca aaaaatcaac ggcatggaga
      601 ggttctgcct gttttctcaa gatcatcggg aaatttgttt cccctaaacc atccatacca
      661 tgagtgtctt gtgcactgat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca
      721 ggaatgtcta aacgatcaca gcgttccagg catttcagca cattctgcgt acctatatct
      781 gcagggacat tcccacaaac tacggtaata gcaactactt cgatatcagg ggatttgaca
      841 gctaatgata aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tacttttcgc
      901 attatttcca atctcctttc tttagagata cttagttttt tattctggga agtttccgaa
      961 ccagtccaag acgagcgtct tgattataat gcacgaaatt agtatactgg cttttattgc
     1021 gaatgtaaat gctctcttac aagtaaatct attgaggaga actttaagta aatgatacaa
     1081 tgaaaaagaa atggaattta cgtgtgccga aaataaagaa tcctatggat cggtacattg
     1141 gataatagat agattatagt ttggcagaaa gcggcgggtg tacaatggtt attttttatt
     1201 tcattcttat tctgataatt atagggatca gttaccattt tctttcttat ttttatgcaa
     1261 agaaattagt aagagcggga gtacagagag gatatgactg gtatgaagac actggtcatc
     1321 gtttgatgga ccctgctgca gtcacgtcag tagaaaaaaa acgacaaaaa ttagaagaag
     1381 agtgtgaaag cttttgggag cagggaacac ccaaaacaat caaaagttat gacgggttga
     1441 aactagctgg tcagatgttc atccatccaa ataagcagaa taaatgggtc atttgcgtac
     1501 atgattaccg aagcacaggg aaaagagaca tgtctcatat aggtaaaaga tatgcagaga
     1561 aaggattcaa cgttcttgta cctgatttac gtgcgcacgg agaaagtgaa ggagaaatca
     1621 tcggaatggg atggctagat cggctagatt taattgcctg gatccaactc atcttagatg
     1681 aacagccgaa tgcgtccatt attttacacg gcggatcaat gggagcttct acgatcatga
     1741 tggcaagtgg tgaaaaactt ccatcagcgg tcaaaggatt tattttagac agcggatatg
     1801 tttctgttta tgcagaattc cgatatatgt taagtaaaat cactgtcttt cctaaaaaaa
     1861 tggtcatgag atatgcgaat cattatgccc agaaatacgc cggttactcc ttaaagcaag
     1921 catcagctac gagacagctt ggcagcaacc atctgccttt attagtcatc catggtgaaa
     1981 gagatcattt tgtccctaca gaagcagcgt acacgattca aaatgctacg gcaggggata
     2041 aagcactgct gcttgttcca gaagcagaac acttggaagc atcgatgaaa gatccgaaaa
     2101 cctattggac agtgattttt tcatttattg aacaaagaat aacgatggat taattttctc
     2161 ttcttttttg taagtaattc gaggataaat aattgtttat agatctggag actgctaaaa
     2221 taaggtagga ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagaa
     2281 gaaaaaaatc gtcttgcttt attcaatgat gagcaacaag agattggaga aatgacatgg
     2341 tcagatgcgg gcccagacat catgatcatt gaccatacat ttgtagatcc agcatatcgt
     2401 ggtcaaaagt tagctgaaaa gctagtgtat actggagtag aattagcaag acgagacggg
     2461 aaaaagatca ttcctttatg cccttatgca aaaaaagagt ttgaaaagaa accagaatat
     2521 caagacgtct tacgtcagtc ataagaataa cagctgaaag ttttgaactt tcagctgtta
     2581 ttccatttat atagagttgt cacggacttt tatctatgat aaagttaaag agacgatatc
     2641 ttttgggaag gaggctgcga tatgtataat ttaattttgg gaatcgtgat cgttttatcg
     2701 attgttatgg tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca
     2761 tttaccggcg gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc
     2821 atgcagcgat caactgcagt tatgggagct atctggatga tcttattatt tgtcctagca
     2881 tatttatctt cgaagtagtt gaataagcct ctcgcaaaac ggcgggcggc tttttttatt
     2941 gcaaagagaa cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag
     3001 gtgagacgag tgagacaatt accaaaaccc ctttatgcaa aacatggaaa gcgagcggtt
     3061 ttgctgcttc acgcttactc aggaagtcca aacgatgttc gaatgctcgc acgatttttg
     3121 gaaaaagcag attatacagt ttatgcgccg ctttttaaag gacacggaac aatggagcca
     3181 tatgatatct tgcaagaaaa agcagaaagc tggtgggcag acactaaaaa agccatccat
     3241 tttttacagt ctgagcagtt ttctgatatt gccgtattag gattatcaat gggcggcatc
     3301 tttgctgtac gagcactaga agaagaatca gtgattggcg gcggtttttt ctgttcgcct
     3361 ttgtctcctg taaaaacaaa cgtgcctgaa aactttgaaa aatacgtacg tcaagtgctg
     3421 aagacagcag gtaaatcaga gaaagaaatc aatgaaaaag cagttgctta ccgctcgtta
     3481 gctgaacaac aattaatgga tatacaagat caggcagcaa tcgtagaaag taggttgtca
     3541 gatatccaac agccgatatt tttagctcaa gctgggaaag atgaaatgat cgaccctaat
     3601 ggcgtatttg aaactgcacg caagttgagc cgtcagcgag tgacacttca atggtatcct
     3661 gaaagtggtc atgtgattac agttggtaca gcaagacgcg aattagaaaa agacgtcttg
     3721 gaatttttag aaaaattacc ttggaatgag gaataaatat gacaaaagaa acgataaaag
     3781 agaaaattct ctttttcatg gaaagcagtc gcaaacgcag tttttctatg gaagaaatcg
     3841 ctgaaggttt agggttccaa aaaagcgatg attttaaatt actagtacaa acgattgctc
     3901 aaatggaaag agaacagagt atagttttca ataaaaaagg aaaagtgaaa cttcctttaa
     3961 aaccaatctt gatcgaagga acatttcgag caaatgaacg aggatttgga tttgtaacga
     4021 ttgatcccga agaagatgac atctatatcc caaaagaagc gactggtttt gcaatggatg
     4081 gagacaccgt agcaatcgat atcatgaagc gagcaaatac agatatggat cgcggagcag
     4141 aggggaaagt agtcgagatt cgagaccggg cgactactca gttagcaggg gaattcgttg
     4201 cttattcaga agaagaaata caagaaacag atctttacgg cgttgttatc ccgaaagata
     4261 gaaagctcaa ccaatttaaa gtatatgcag cagcagaggg agttcgtcca gttgacggaa
     4321 gtattgtgct gatcgaactg acccattacc ctgaaaaagg gtatgcgact agtttagaag
     4381 ggataatcaa gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcaattg
     4441 tcgtggctaa tggtatccct acgaaatttc ctgatgatgt attgtctgaa gcagatgaag
     4501 ttccagatca aatcagcgaa aaggatataa ctggacgtag agatttaaga aatcagctca
     4561 ttgttacgat tgatggagaa gatgcaaaag atctagatga tgcagttacg gttaaaaaat
     4621 tagataacgg taattatttt cttggagtac acattgcaga tgtttcttac tatgtgacac
     4681 aaggcagtca attggacaga gaagcatatg aaagagggac aagtgtatat ttgactgatc
     4741 gagtgattcc gatgatcccg caacgtttat cgaatggtat ctgttcactg aatccccatg
     4801 ttccaaggct gaccatgagt tgcgaaatgg agattgatcc aaatggacaa gtagtctctc
     4861 atgatatttt cccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc
     4921 aaatcttaga agatcaagac gaagaaacga tgcaacgcta tgctcagctc gtacctatgt
     4981 tccaagaaat gggtgaattg catcgaatcc ttgaaacgat gcgaatcaaa cgtggcgcga
     5041 tttcttttga ggatcgcgaa gcgaaaatcc ttgttgatgc tgaaggacac ccaaatgaca
     5101 tccagctaag aagcagagga attggtgaac gcttgatcga atctttcatg cttgcggcca
     5161 atgaaacggt agctgaacat tataataaat taaatctgcc gtttatttac cgaatccatg
     5221 aacagccaaa agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc
     5281 tggtccgagg aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag
     5341 tagaagacaa accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag
     5401 cacgctattc agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact
     5461 ttacatctcc tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca
     5521 gtgaagataa aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag
     5581 atcatagttc taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga
     5641 agaaagcaga attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg
     5701 ttgtgaaatt cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca
     5761 atgaattgaa acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa
     5821 gaactggtct gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc
     5881 cagatgaacg agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac
     5941 gtccaaaagc acgcaatgga aaatttggaa aacgagaagg aaaacaagca ggcaaacgct
     6001 cagaaaaaaa tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga
     6061 aaaaagggaa aaagccattt tacaaagatg tcaaaaagaa gaaaaagaaa aaataaaatg
     6121 agttggagga aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag
     6181 ctcgccatga ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg
     6241 agatcaagtc gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca
     6301 acggggaagc tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta
     6361 atcatgatcc gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg
     6421 aaaacgaatt gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg
     6481 gctatgccaa ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag
     6541 atttgaaacg aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat
     6601 aatttcatta tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg
     6661 ttagcattta atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg
     6721 tgcatgggga aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga
     6781 aaatgttttg aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg
     6841 aaaaaaccag atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat
     6901 ggattggatg aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt
     6961 tgtataatgg tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga
     7021 aatcttaagt tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt
     7081 cgaggaatcg taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca
     7141 tttacattgt ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc
     7201 ttacctaacg aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact
     7261 ttggcattta taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa
     7321 ggatatttcg taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt
     7381 gaagaattta caaatttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg
     7441 gaagttttgc taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca
     7501 ttagcaattc cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa
     7561 gcatttgtct ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa
     7621 taatactcgg ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa
     7681 ttatatcgca gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg
     7741 tcaagttatc tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt
     7801 ccgtacaaca atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt
     7861 tatcgccttg attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat
     7921 cgtttgttac tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc
     7981 tatgctgaat caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt
     8041 tgtcagcggc tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat
     8101 cagcgatatt ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca
     8161 atctcgcatc aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg
     8221 ttctgatgca gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa
     8281 tattttgaag gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat
     8341 cactgtagaa cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct
     8401 tcaaatcgcg gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat
     8461 caatcaatac attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa
     8521 gacgttacgg gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct
     8581 atcaagatct cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt
     8641 taagtgatgt tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg
     8701 gttatgatgg gatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg
     8761 accttttgtt catgatcgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat
     8821 tgggaagtgt cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga
     8881 atgttgcaaa aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta
     8941 ttattggtgg cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc
     9001 aattagaaaa aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg
     9061 gccatcaaag cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac
     9121 gtgctttcag tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca
     9181 catggtttag aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga
     9241 atggcgcaaa acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc
     9301 attcgtgaag gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag
     9361 gccttgatcg gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc
     9421 gttactgaca aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct
     9481 gttaacgaac caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc
     9541 ggacaacgtg aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgatcgat
     9601 acgatcatca accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa
     9661 gattctacag ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca
     9721 atcgttgtga atgccggtgc gtctcaacca gcaccattgc tttatatcgc accatatgct
     9781 ggtactgcaa tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat
     9841 gatctttcaa aacaagctgt tgcttatcgt gaactttcct tgctgcttcg ccgtccacca
     9901 ggtcgtgaag cttatccagg ggatgttttc tacttacact cacgcttatt ggaacgtgca
     9961 gcaaaattaa gtgatgattt aggtggcggt tcaatgactg ccttaccatt tgttgaaaca
    10021 caagctggag atatctctgc ttatatccca acaaacgtta tttcgatcac tgatggacaa
    10081 atcttcttag aaagcgactt gttctacgca ggtactcgtc cagcggttga tgccggacta
    10141 tctgtatctc gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact
    10201 ttacgtctag acttagcaag ttaccgtgaa ttagaagcat ttacacaatt cggttctgac
    10261 ttggatgcag caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa
    10321 caaaaattgc atgcaccgct agctgttgaa aaacaagtag tgattttgta tgctttgaca
    10381 catggattct tagatagtat ccctgtagac agtattttag acttcgaaca tgaattattc
    10441 gaatatctgg ataccaatca ttcagatatc tttgaaacaa tccgtacaac aaaagatctt
    10501 ccagaagaag aagcgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca
    10561 aaaggaaata attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt
    10621 gagatgaatg ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac
    10681 gagccaaatc acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc
    10741 ttcttcacag aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac
    10801 tgctactcag ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag
    10861 catgttgctc agccgtcctg ttaagaaaac gggttatatc gtcatcactg cagatggcgg
    10921 tttagtcggt ggatataaca gctcgatatt gaaacaaacg atgtctattt tagaagaaga
    10981 ccaccaatca cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt
    11041 taaagcacgc ggtatcaatc tagcatatga gctgcgcaat ctatctgatc agccaagctt
    11101 tgatgaagtc cgcaaaatcg taaatatggc aacaactatg taccaaaacg aagtattcga
    11161 tgaattatac gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga
    11221 aaaaatgctg ccaatctcag acttagatcc agaagaagca actactttcg aacaagaata
    11281 tatttttgaa ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag
    11341 tttgatctac ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc
    11401 aatgaaaaca gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttacaa
    11461 ccgtgcaaga caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc
    11521 actagaatag tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa
    11581 tcggtcccgt tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg
    11641 cattagttgt ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag
    11701 aattagggga cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag
    11761 gaatggaagt cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag
    11821 gtcgcgtatt caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg
    11881 cggaaagaag cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag
    11941 aaattttgga aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga
    12001 aagtcggact attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc
    12061 ataatatcgc ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc
    12121 gtgaaggtaa tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca
    12181 tggtgttcgg acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt
    12241 tgacgattgc ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca
    12301 acattttccg tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt
    12361 ctgcggttgg ttatcaacca acattggcaa cagaaatggg tcaattgcaa gaacgtatca
    12421 catctacgaa aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact
    12481 acactgaccc ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac
    12541 gtaaattaac agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg
    12601 ctttagcacc tgaaatcgtg ggagaagaac attataaagt agcaacagaa gtccaacacg
    12661 tattgcaacg atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat
    12721 ccgatcaaga aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa
    12781 actttaacgt ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa
    12841 cagtgaaagg attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt
    12901 tccgaagtgt tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga
    12961 aaggggtgcc ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc
    13021 tatgatcacc atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg
    13081 cctaaacatg caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca
    13141 gattcagata cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat
    13201 aatgttgttt caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt
    13261 gcggaacgtg caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat
    13321 acgaacgaat tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta
    13381 tctaagcact cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag
    13441 gttatgacag aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca
    13501 aatttttgtg aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatcg
    13561 gaggttgtga aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct
    13621 catattttgc cgttttttga gctaataccg agggtcagat gattgaacac cgtttatttg
    13681 gaataaggga ctgcgacaag acttt
//
LOCUS       DAKCAA010000066        13305 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000066 DAKCAA010000000
VERSION     DAKCAA010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.067"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..311
                     /locus_tag="OUE31_002193"
     CDS             <1..311
                     /locus_tag="OUE31_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCU0223175.1"
                     /translation="IHFARREKKLYRSLYLEEYGGGKEMQNFSYTYFVNTVKRDPAYV
                     NLSEEQIESLYNGTWIIATGIAALMSSSIIHPTDEQIEKMIQDSIDAILKFKEPIEID
                     "
     gene            complement(489..929)
                     /locus_tag="OUE31_002194"
     CDS             complement(489..929)
                     /locus_tag="OUE31_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCU0223176.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLSGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            1087..1851
                     /gene="map"
                     /locus_tag="OUE31_002195"
     CDS             1087..1851
                     /gene="map"
                     /locus_tag="OUE31_002195"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HCU0223177.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            1883..2806
                     /locus_tag="OUE31_002196"
     CDS             1883..2806
                     /locus_tag="OUE31_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HCU0223178.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            2882..4021
                     /locus_tag="OUE31_002197"
     CDS             2882..4021
                     /locus_tag="OUE31_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HCU0223179.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            4014..4814
                     /locus_tag="OUE31_002198"
     CDS             4014..4814
                     /locus_tag="OUE31_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCU0223180.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            4814..5641
                     /locus_tag="OUE31_002199"
     CDS             4814..5641
                     /locus_tag="OUE31_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCU0223181.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            5619..6353
                     /locus_tag="OUE31_002200"
     CDS             5619..6353
                     /locus_tag="OUE31_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCU0223182.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            6453..7319
                     /gene="rfbA"
                     /locus_tag="OUE31_002201"
     CDS             6453..7319
                     /gene="rfbA"
                     /locus_tag="OUE31_002201"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCU0223183.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            7333..7905
                     /gene="rfbC"
                     /locus_tag="OUE31_002202"
     CDS             7333..7905
                     /gene="rfbC"
                     /locus_tag="OUE31_002202"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HCU0223184.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            7927..8955
                     /gene="rfbB"
                     /locus_tag="OUE31_002203"
     CDS             7927..8955
                     /gene="rfbB"
                     /locus_tag="OUE31_002203"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCU0223185.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            9053..9904
                     /gene="rfbD"
                     /locus_tag="OUE31_002204"
     CDS             9053..9904
                     /gene="rfbD"
                     /locus_tag="OUE31_002204"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HCU0223186.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            9938..11971
                     /locus_tag="OUE31_002205"
     CDS             9938..11971
                     /locus_tag="OUE31_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223187.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPAKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKIDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKEIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            12015..13295
                     /locus_tag="OUE31_002206"
     CDS             12015..13295
                     /locus_tag="OUE31_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HCU0223188.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVCTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIATLLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
BASE COUNT         4083 a         2251 c         2821 g         4150 t
ORIGIN      
        1 atatccattt tgcaagaaga gagaagaagt tgtatcgttc actgtactta gaagaatatg
       61 gtggaggaaa agagatgcag aatttctctt atacttactt tgtgaataca gtgaaacgcg
      121 atccagctta tgtgaatctt tcagaagagc agatcgaatc tttgtataat gggacatgga
      181 tcatagctac tgggatcgca gctttgatgt cttcaagcat catccatcca actgatgaac
      241 agattgaaaa gatgatacaa gacagtatag atgctatctt gaaattcaaa gaaccaatag
      301 aaatcgattg aatatactca aaagttccac aaatcagtag ataacaagag atgtgtcaaa
      361 ataaggaaaa gttcgttttt cttacagcgt atgcattttt aactcccgaa gaactcttcc
      421 atgaatgcaa tgaataaaag agccgtacag attgaataaa tctggatggc tcttttattg
      481 caagtatatt aaatttttgc gactagttct ttagcgaaag cttctaaatt ttcgatatct
      541 tcttcttcag cattcagatc cactttaaca ttttcggctc cttttgatgc gcctgttttt
      601 gcaaaagcag catcgaaatc atccaccgat ttgcagaatt catcgtaaaa agtatcacca
      661 gatccgcaga caccgtaaat ttttcccgat agatccaatt cttgcaagtc ttcataaaag
      721 tctacgatct catcaggcag atcgccatca tcgtatgtat aagtagctac tacgcaaata
      781 tctgcctcct cgaattcatc tgcatctact tgggtacatt cgttgatttc gacttcgata
      841 tccagatttt caaatgcttc tgcaacaata tcggcgattt cttcagtgtt tcctgtcatg
      901 ctagcatata cgatttttgc taaagccatg atgtgcctcc tcgtttataa ttatttaaca
      961 attatgaatt ataccaaaac atcattgaaa agaaaataaa acctagagac acctggggaa
     1021 tgtcatttgg ctaaatgtat gccgctatgt taaaatgaga gggatttgta aaaaggagac
     1081 gaaaatatga ttactttaaa atcagcacgt gaaattgaaa tgatggcaga atctggagct
     1141 ttattagcag atgtacataa aaatctgcgt gattttataa aaccaggaat cacaagttgg
     1201 gatattgagg tatttgtcag aaactatatc gagagtcatg gcggaattgc tgcgcaaatt
     1261 ggctttgaag ggtatgaata tgcgacttgt atcagtataa atgatgaaat ttgtcatgga
     1321 ttccctcgta aaaagccttt gaaaaacggt gatttggtaa aagtcgatat gtgtatcgat
     1381 ttgaaaggcg gcatttctga ttcttgttgg gcctatgtag ttggagaatc tacacctgag
     1441 atcgaccgat tgatggaagt aacgaagaaa gctttgtaca tcggtattga gcaagcacaa
     1501 gtagggaatc ggattggtga catcggtcat gctatccaaa cttatgtaga aggcgaaaat
     1561 ctagcgatcg ttcgtgattt tattggtcat ggcgttggtc ctacgattca tgaagaacca
     1621 gcagttcctc attacggaga agctggaaaa gggttgcggt tgaaagaagg catggttatc
     1681 acgatcgaac ctatggttaa taccggaact tggaaaatga aaatggatcc taacggctgg
     1741 actgcgtata caagagacgg cggactttct tgccaatatg aacatacatt ggctattact
     1801 aaagatggtc caagaatttt gacatcacaa ggagaagaag gcacttattg atctatccag
     1861 tcaataggta cgggagaggt acatgaaagt ttggaacaaa ataaaacaaa atgaaaatct
     1921 gatgcgcttt attgagacga ctcaaaagcg catcactgat tcagaaatga gtacgacctc
     1981 tgtcgtcgtt gcttattatt tactcttgtc tttatttcca ttgattattg cttttggtaa
     2041 tattttaccg tttctccaca tcgatcaaga gactgtactg acctatttac gagaagtgat
     2101 tcctgagacc gtttaccagt ttatcggtcc tgcaatcaaa gaccttttga cacaaagttc
     2161 aggaggcttg ttatccgttt ctgcattagc ggctttatgg tctgcaagtc aaagtatcaa
     2221 tgctttgcaa attgcgatga ataaagcgta tggcgtagaa aatagaaaaa attttttgat
     2281 cgtccgtttc ttctcactaa ttgtcattgt cttgttcatg attgctatta gtggggtaac
     2341 tatcgttctt gggttgggac agctgatttt ggatgctatt cagccaatcg tacaaatacc
     2401 cgtgaacttt atcgatcagt tccaaacttt gaagtggcca atcacattgg tagctttatt
     2461 tgtcatcatg ttcttgattt atttaattgt ccctaatgct cagttgaagt tgaagacgat
     2521 cattccgggc acgatcttcg ctactgtcgg ctggatgctg ttatcacaag tgtttagtat
     2581 ctatgctagg tattttgcaa cgaggatcag cggttatcag atcataggaa gttttattgt
     2641 actcatgctt tggcttaatt ttgctgctac gatcatcatt ttgggcggaa tcatcaatgc
     2701 agttgttcaa gaatacgtga cgggtcatca aatcaaaaaa cgtcgagatc caagccgaaa
     2761 atggttcaat aaattgaaaa ctaaattttc tcataaaaaa aagtagaaac aagagttctt
     2821 attgtaaatt tatatcagta atttataata attatgactc ttaattaaag taggtgccca
     2881 tatgcttgtt tcttttagta tggttataag attttttctg acaattttat tatcactgat
     2941 attaacacct gtattcaaaa tcatttcagt acaaacaggt atggtcgaca aaccaaatga
     3001 aagaagaata aataaagttc caatgccttc agcgggcgga ctgcctatct ttatttcatt
     3061 tgttatatcg actttattct tattccgtaa aattatccct caatcgtata ttgtaccgat
     3121 cttgattgct tctttagtaa tcatagtcac aggagtgctc gatgataaat atgagctgac
     3181 acctaaacaa aaaagtatag ggatcttgat tgcttctctt attatttatt ttgtagcaga
     3241 tatacgtatt gattccttca cgcttccttt tattggatat atccaactag gctggcttag
     3301 ttttcccgta acgatttttt ggatcttcgg tatcacgaat gcggtcaatc tgattgacgg
     3361 tttggatggg ctggcggcag ggatttcatt gatcggttta attacgatag gaatcattgg
     3421 atattttttc ctccatgctt ctacagtgta tattccagtt gttattttct gtcttgtagc
     3481 aagtattatc ggtttttttc cttacaattt ttatccggca aagatttatt taggcgatac
     3541 aggagctcta ttcctagggt ttatgatggc cgtcctttca ctacaagggc tgaagaacgt
     3601 gacttttgtt tcatcgattt ctttgctgat cgtcatggga gtgccggtaa cagacacgtt
     3661 ttttgctatc attaggagaa aagcaaaccg tgtttctttt tctacagcag ataaaaaaca
     3721 tcttcatcac cgactaatca gtttaggctt tactcataaa ggtgctgtcc tgacgattta
     3781 tgcgatggct ttgatgtttt ctttcacagc tatggtcatg aattatactg gaagaatcgg
     3841 aacgatcata ttgattattg ccatgttgtt tgctgcaatt ttattatttg aattgattgg
     3901 tctgatcaat gagaaacatc agtttatttt aaaaacattg cgatttttag ggaataaaga
     3961 gtaccgtacg caagtaaaac agaaatattt gaagaaatgg aaccgtcata tagatgaata
     4021 acaaattaaa ccagccgatc cttattagta ttgtgacggc aaacagtgat aaaatttttc
     4081 ggacactaga taattttatt tcaactgtaa aagatgaaac agcagtaaaa atccgaattt
     4141 ttgacaacaa ttcacttccc gagtacaaaa aaagactaac agagtatagg aaatatccct
     4201 acatcgatat ctattttcat gatgaaaatt ccggatttgg ttatggacat aatcacaatc
     4261 tgatagctag cgattctcgc tatggcatta tttgtaaccc agatatttta gtggatgaag
     4321 agacagttac agcattggtc ttgttattga aagaacatcc ggaatgtgcg atgttagcac
     4381 ctaagattct taatgaagat ggaacaactc agcacctcat ccgtgagcag ctggctgttt
     4441 ttgattacgt tttgcgcttt gtgcctttca aatgggtcaa aaaaaagttt gacaaacgac
     4501 tggctgtgtt tgaatgccga ggattgccta ctgatgctaa tagttatgta cggatgatct
     4561 caggtagttt tatggtagct gatattgata aatttaaaga gataaagggg tttgatgagc
     4621 gtttcttcat gtactttgaa gacaacgact tgtgtttgag ttttgaaaaa gcaggttaca
     4681 agttattgta cacacccttt tatgcagtta tccattttta cgggaagggt gcgcatcgaa
     4741 atgcaaaact gtttcgcgtg tttttgactt ctatgatgaa atttttcaat aagtgggggt
     4801 ggcgtttttt ctgatgaaac cagaaatatt agtagtcgtt gtgctttatc agcaactatt
     4861 cagtcaatct ccagcttatg gaccattaag caaagcactt agcgaaaagc aaattcagct
     4921 tattatttac gataatagtc ctcaaaggca gcaaaatgag ctgtttgaaa aagaaaatat
     4981 cgtttatcat catgatccgc aaaatcctgg tttagcggtg gcttataatt ttgcgttgtc
     5041 tcaagcagat gaaggaacac gttgtctcgt cactctggat caggatacga ggctagtcga
     5101 cgattatttt gaactattgc gtaaagtaac ctttacagat gaatgtgttg ctgcagttcc
     5161 gatgattttt tctgggagcc gacaagtttc tcccctatat tcagatcgtt atatcaatcg
     5221 tacagctcaa gcagtagaag ttgaaggccc aacagctgaa cgaatcatgg caatcaattc
     5281 aggtgttgcc tggtctgtca aatttctaaa aaagattggc gggtttaatc ctgctttttc
     5341 tttagatttt ttggatcatt ggctgttttg gaaagtggat cagttggaaa aaactgtgga
     5401 gatccttcct gtacgaatgg aacatgatct ttcggtttta gactatgaaa aagtttcaag
     5461 taatcgatac cgttctattt tacaagcaga aaatcgattt tatcatgaat atgatcaaag
     5521 gcatttatcc agtcaccgac gacaattatt gttaagaaca gctaaacagt tcttgaccgt
     5581 caaaaaccgg catatctggc ggatgacttt gcgctcatat gttaagaatt ggaaggtgtg
     5641 aattcgtgcg ttcggtttgt atagctacct ttaatggagg cagatattta agagagcagt
     5701 tagatagtat tttatctcag ctttcagcag aagatgaagt agtcatttct gatgatgggt
     5761 cagtagatga tacatgggat atattaactg aatacgcaga aaaagataag cgaatccagc
     5821 ttttttcggg gcctcgtcaa ggattgatcg ctaattttgg ttatgcgatc cagcagacga
     5881 aaggagatct aatctttttg gcagaccaag atgatgtttg gttggagaca aaagtgaaaa
     5941 agatcactga ctattttgag cagaatccgg atcagctagt agtagtttct gatttaatca
     6001 ttgtggacag cgagctgcaa gagatccatg attcgtattt ttcgtttcga aattccaaag
     6061 aaggatggct taataatgtg ataagaagtc actatattgg tgctggtatg gctttccggt
     6121 cttctttaaa acccgatatt ttgccgatcc cgtcagaagt gccgatgcat gatatgtgga
     6181 ttggtttgct gggaggaaag aagactgggt tcctaagaga accgttaact ctgtaccgaa
     6241 gacatgattt aaacgcgagt gagattgaaa cacattctaa attacggcaa aaaatttctt
     6301 ggcgtgttca tctgattacg gcgttgatca aacgaaaatg gtttaaacgt tgataaaaga
     6361 tgtttaaatc cttaatattt ccatgacaaa tataacaatt gatgagataa taacaaagtg
     6421 aaatttgaaa tcaaaaagga gagcagatat ccatgaaggg aatcattctt gctgggggca
     6481 gcggaacacg tctgtaccct ttaacaaagg caacatcgaa acaattgatg ccgatttatg
     6541 acaaaccaat gatttattat ccaatgtcta ctctgatgtt ggcgggaatc aaagaaattc
     6601 tgattatttc aacgccacaa gatacaccac gtttcaagga attatttgga aacggaaatg
     6661 atttaggact gcagatcgaa tatgcagtac aagaaagtcc agatggattg gcacaagcgt
     6721 ttatcattgg agaagaattt attggagatg atagtgtctg cttggtatta ggggacaata
     6781 tttactatgg tggcggtctg tctaaaatgt tgcaacgagc agcttcaaaa gatacaggcg
     6841 cgacagtatt tggctatcat gtcaatgatc cagaacgctt tggtgtagta gaatttgatg
     6901 agaatatgca agctttgtcg attgaagaaa agcctgctca gccaaaatca aattacgctg
     6961 taactggcct ttatttttat gacaatgagg taatttctat cgctaaaggt atcaaacctt
     7021 cagaacgtgg agaactagag attacggatg tcaataaagc atatttggat aaaggaaaac
     7081 tatccgtaga acttatggga cgcggatttg cttggcttga tacaggaaca catgaatcat
     7141 tgcttgaagc atctaccttt atcgaaacaa ttgaaaaacg tcagaactta aaagtggctt
     7201 gtttggaaga aattgcttac cgtatgggct acatcgataa ggaacaattg ctggcccttg
     7261 cacagccatt gaaaaaaaat caatacggtc aatatttatt gaatttggcc gctgaataag
     7321 gagtccttac agatgaaagt aacagataca aaattaacag atgtcaaaat cgtagaaatg
     7381 gacgtctttg gcgatcatcg cggtttcttc acagaaagtt attcaaaagc aaaatttgca
     7441 gaacatggat tgaaatatga ctttgttcaa gacaaccatt cactatcagc tgaagctggt
     7501 gtccttcggg ggcttcattt ccaaaaagga gaagctgcac agacaaaatt gattcgggta
     7561 gtcactggag cagttttaga tgtagtagtg gatatccgca aaggtagccc gacttatggt
     7621 caatgggacg gatttatctt atctgaacat aatcatcgac agttgcttgt acctaaagga
     7681 tatgcccatg gattcgttac tttgacacca aatgtgaact tcctttataa gtgtgataat
     7741 tactataatg cagaagcaga tgggggcatc gcatttgatg atccagattt agcgattgat
     7801 tggccaattg atccatcaag agcgattatg tcggaaaaag atcaccgtca tccgacatta
     7861 aaagaatttg aagcagaaaa tccatttgtt tacggagaaa tctaagaatt aaggagaaat
     7921 tttcttatga aaaacatcat tgttaccgga ggtgccggat tcatcggctc taatttcgtt
     7981 cattacgtgg taaacaatca tccagaagtg catgtcactg ttttggataa actgacttat
     8041 gcaggaaaca aagagaactt ggctggactt cctagcgatc gcgtagaatt ggtcgtagga
     8101 gatgttgcag atgcagaatt agtggaccgt ctagtaaaag aagcggacgc agttgttcat
     8161 tacgcggcag aatcccataa cgataattca ttaaaagatc ctttcccatt tgtacaaacg
     8221 aatatcattg gtacgtatac acttttagaa gcttgccgca agtatgatgt acgctatcat
     8281 cacgtatcta ctgacgaggt ttacggcgat cttccattac gtgaagacct gccaggacat
     8341 ggggaaggcg aaggagaaaa attcactgcg gaaacaccat ataatccttc aagtccatat
     8401 tcttctacaa aagctggttc agatctgtta gtaaaagcat gggtgcgttc ttttggctta
     8461 cgtgcaacca tttcaaactg ttcaaacaac tatggtcctt atcagcatat tgaaaaattt
     8521 attcctcgcc aagtaacgaa tatcttaagc ggtattcgtc caaaattata tggcgaagga
     8581 aagaatgttc gtgactggat ccatacgaat gatcattctt cagcagtgtg gctgattttg
     8641 acgaaaggca gaattggcga aacctatctg atcggtgcag acggtgaaga agataataag
     8701 accgtgatgg aattgatctt agaaatgatg ggtcaaccaa aagatgcgta cgaccatgta
     8761 aacgaccgtg caggacacga cttgcgttat gcaatcgatt cgacaaaatt acgggaagag
     8821 ttaggatgga agcctgagtt tacgaacttc cgtgatgggt tggctgacac gatcaaatgg
     8881 tacgaagaac atgaagactg gtggaaaaaa gaaaaagagg ccgttgaagc agcatatgcc
     8941 aaaaatggac aataatacag agaaaatgtc actgtattaa tggaaaaaca catgtgaggc
     9001 aggcgctcgc ctgtctcttt tttaaaataa aaatcaagga gcggataatc atatgttttt
     9061 attaactgga ggaaatgggc aactaggtac agaattgcgc catttattag atgaaaaaaa
     9121 tctgcaatat gtttcaacag atgcaaaaga cttggatatc acagatgccg agaaaacaat
     9181 ggcttacatc acagaattaa aacctgatgt tattttccat tgtgcagctt acacagcagt
     9241 agataaagca gaagaagaag caaaagaatt agatgagaag atcaatgttg atggtacaag
     9301 aaatgtagca cttgcagcaa aagctgtgaa tgctcaattc gtctatatca gtacagacta
     9361 tgttttcgat ggaaaaaaca aaaatgtaga atacgaagta gacgaccaaa cgaatccact
     9421 aaatgaatat ggtcgtacga aattattagg cgaaaaagca gtagaagaga ttttagaaga
     9481 ctattatatc atacgaactt cttgggtttt cgggatctat ggacacaatt tcgtcttcac
     9541 gatgcaacgc ctagcggaaa cccgcgacaa actgactgta gtaaatgacc agtttgggcg
     9601 accaacttgg acacgtactt tggcagaatt tatggtatat gtcatcgaag aaaaagcacc
     9661 atttggtatt tatcatttgt cgaacgaaaa tagctgttct tggtatgaat tcgcaaaaga
     9721 aatattgaaa gatacagatg tagaagttgc acctgttacg tcagaagaat ttccgcaaaa
     9781 agcaacacgt ccgcagtatt cagtcatgag cctgaaaaag acagaagagt taggatttgt
     9841 cataccaact tggcaagaag cacttgcgca aatgctggaa gctgccaaaa aaatgaataa
     9901 gtaatttcct tttatcaaat agaatttgga gcatgatatg gaaaaacaaa caagaagtgc
     9961 acgacgaaaa gaaaagccaa aagcgaacca ggcagattcg aatttggtgc ttgacctgtt
    10021 tctaaaactc cgctatctta ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt
    10081 aaacggaagt tcacttggtg tttgggataa atatgtgtcg caaagagacg atgggaaaaa
    10141 aactgatgtg atttttggac agaatcggga agtgcggtca gacgaatggc tggtgcagac
    10201 acctttttac ctctcacaag ctgaagagga ctttccgttg gtgaacgagg attattcatt
    10261 aaacggacaa aacatgatca ttgcgtataa ttctcctgca aaggatatta cggttatcgg
    10321 aaaaccattc aactggggat tctttttcct cggaagagat cgaggacttt ccttttattg
    10381 ggcgatgaaa ttagtcgtca tggtcttgct tggattcgaa gtactgatga tattaacgaa
    10441 gagaaaaaaa gctctatcgc taatcggtgc atttgcgctg acattttctc cagcagtcca
    10501 gtggtggttc atgcaacatg tgggcgattt gattttcttt actttgggac tgatgactgc
    10561 tttttatcat tatttctaca atcatgataa aaaatggcta cgaacgttga tgatgctttt
    10621 ggtggttatt ttcggtattg ggtttatttt agtgatttac ccagcccatc aagtgatgct
    10681 ggcgtacttg ctgatttttt attttgttgg cctgcttatt tactatagca agaaagtttc
    10741 atgggatctg ttggatgtag tgttgattgg aggggcagtt ttatttattg gcggagtcat
    10801 ggttcatttc tggctaacgt caaaagacgc attgttagct tctttgaata ccttatatcc
    10861 aggaaaacgg gtaagtactg gaggaaagtg gacgattggc gaattttttt ctttccttac
    10921 aaattggaaa attccttttg aagatatcaa ctattcgaat aactctgaag tggccctgtt
    10981 ctatcacttt tttccaactg tattcctagc aagtccattt gtgttatttg gcaaaaaaga
    11041 tagcgaacaa aagttactgg gacgtatttt gatgattttt tgtctgtttt ctatcttttg
    11101 gattaccgtt gggttgccaa aatggctagc agaaatcact ctgctgtctt atgttcctcc
    11161 attaagagcc atccttactt ttagttttgc ggcttgttta ttatcgatct ggtttatcgc
    11221 ttatatttgg agagaagatg ttattcctat ttggtataaa ttcattttgt tggcagtaaa
    11281 tgcatggtct tatttctatg cgattacgca ttcgaaaata gataattatt tttcggattt
    11341 tgaaaccatc gcagttgctg tgttgggaac agtgatttta gcatttgcat tatttggctg
    11401 gagacgcttg ttttacctcg cttttgccgc cttagttatc gtatctggct ttttcgtcaa
    11461 tccagtcgta gaaggtacag gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa
    11521 aatcgatcaa caagatcctg gtaaagtttg gttgtctgaa gatgaattat ataacttcac
    11581 cccaacattg ggagtgaaat ccttcaatac agtacgcttt tatccagata tagctgcatg
    11641 gaaggaaatc gatccgaaag aagaatacga gaagtattat aatcggtatg ctcatacaag
    11701 agcttttatc gctaaggaag atacaaagtt cattttagat cgtccagata tgttttcggt
    11761 cacgttgaat tttgaagacg cagaaaaatt agggatcgac tatgtgatca gtaaacgacc
    11821 attaactgat tacaaccaat tatatgaagc gcagttcacg cagctatatg gaccggataa
    11881 agacggttat atgattttta aagtagaata tccggattat ccagatgtac cacaaacaca
    11941 aactcaggaa aatcagctag tcgtacagta ataggctagc tgagaataat cctgaaatat
    12001 tagtagaaag gagagtggag ataattcaag caatcgtaca aaaatttgtc aacaaaatga
    12061 gtgtcggttt cttgcttttg ttgctgacgc tagtcttttt tgtttgtaca gcagggttag
    12121 gttttccagc aactttgttt atatataaca atagttcatt acttatcgct tttagtgtgg
    12181 ctattttgct cattttaaat gtttataaag caaaaggcgt cgattttctt tatctaggtg
    12241 ttgcgcttgc ccttttcatt ttcttttctt actttcggga attaagaaat gagtctttat
    12301 ttggagattt actgtttcct ttgattattt tattttgttt agtaattaaa tggatcgagt
    12361 ggacaaaatg ggatcgcggt atttatctga ttgtctttac ggtcttcctc ggaatcacgt
    12421 tatatcgtgt atttacagag atccaagtac cagaaggaca aagcatctgg gctccaggca
    12481 attcgctttc tgatatttgg atcaatacga atacaatcgg aagttctttg atgactcttg
    12541 ctttattgat cagtggattt gccagttctt ttgaacgatg gtatgtacga atcatcggtg
    12601 cagtagcagt tgttgcagct tttctcggga tttgggtctg ccaatctaga ggtgcattag
    12661 tcgcgttgat tgtttttgcg atattggatc ttttacctaa atcgttgatg cgtgtcattc
    12721 gtgcgccatt tattgcttac acggttacga ttcttttagc tttgccgatt tcttatctgg
    12781 cggctgtctc tgaaaaagtc aatttgttta ccggtcgaga agatatttgg cataaattct
    12841 atcagacgct aggagaaaaa tctgaacaag ttttactagg aatgaaaaca tttatcttcc
    12901 aacgaggaaa ccaattttta ggaaaccaca atagttataa ttctattttg aatatctatg
    12961 gattgatagg atttgggatt gctactttgc tgcttatcct ttttattggt cgcttaacgt
    13021 tgaaagcaga tttatccaac gggcagatga cttttatctg ggcctttttt gcggtgatga
    13081 tgcagtcatt tatggaggat acattgactt catacccatg ggttccgatt atttatatcc
    13141 tgttggctat ggccgttcat cgatatgatg aaccagaagt tgcggaggaa ttctatgtta
    13201 tggaagaggc atatgacgat atgacttatg atgatacatc ttatgaggaa caaccagata
    13261 gcgctcattc ttccaggatc caacgctatc attgataggc acaaa
//
LOCUS       DAKCAA010000067        13212 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000067 DAKCAA010000000
VERSION     DAKCAA010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.068"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(86..2020)
                     /locus_tag="OUE31_002207"
     CDS             complement(86..2020)
                     /locus_tag="OUE31_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCU0223189.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            2301..3257
                     /locus_tag="OUE31_002208"
     CDS             2301..3257
                     /locus_tag="OUE31_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HCU0223190.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3347..4450
                     /locus_tag="OUE31_002209"
     CDS             3347..4450
                     /locus_tag="OUE31_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HCU0223191.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            4463..5416
                     /gene="menA"
                     /locus_tag="OUE31_002210"
     CDS             4463..5416
                     /gene="menA"
                     /locus_tag="OUE31_002210"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HCU0223192.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(6230..7576)
                     /gene="gor"
                     /locus_tag="OUE31_002211"
     CDS             complement(6230..7576)
                     /gene="gor"
                     /locus_tag="OUE31_002211"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HCU0223193.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(7710..8963)
                     /locus_tag="OUE31_002212"
     CDS             complement(7710..8963)
                     /locus_tag="OUE31_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCU0223194.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(8969..9892)
                     /locus_tag="OUE31_002213"
     CDS             complement(8969..9892)
                     /locus_tag="OUE31_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCU0223195.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(10113..12605)
                     /locus_tag="OUE31_002214"
     CDS             complement(10113..12605)
                     /locus_tag="OUE31_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HCU0223196.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(12612..13079)
                     /locus_tag="OUE31_002215"
     CDS             complement(12612..13079)
                     /locus_tag="OUE31_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HCU0223197.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         3861 a         2760 c         2321 g         4270 t
ORIGIN      
        1 aattttacat aaaaaggagg ctgtgacggt ttgtctcagc ccctttctat tgaaatcttg
       61 cattcaaata acgttcttta tctatttatt tcttgccgta ctgggaactt ggtctaccgt
      121 accaccaatt acctagtgta cgttgtagcc atggaattac ccagcgatcc aacccaatcg
      181 cacgtccgga accgttcatc aatgcgaaag caacaaaaat gaaccaaatg tttacccagt
      241 aaaacatgcc tgataagcag aacgtgatca ccaatacaat cgttgtcgca ctgcatagcc
      301 atgtgaataa tccagcaatc aatgctaatg ccaaggcaat ttcaaagaat accatgaatt
      361 tttggaagaa cattgctaca tcattgtttg gcatgatcac ttgcatgatc tttgtgaacc
      421 agtctggtga cttctcaatc acagccattg gttcttcacc gtatgcataa ctcaaaccaa
      481 aatgtgcagc ttgagtcgct gcttctccgg cacttgcccc tgctccgctg gcagctgtgg
      541 ttgcatcacc agcagcagaa gcaccactgg caacatctgt tacattgtat tcccatgtcc
      601 aagggaacac actgtttcca gtgaaccatg atccttcacc aaaccaagta cttggtttga
      661 acacttcacc attcccaatg atttttttgg aagcttcaac gaaccaaact aaaccataga
      721 aaatacgaag tggcacactc cataagacat tgccgtaacg agaagaatgt cctcgagtca
      781 cgttgcgatc atctttgata tggaaaaact catgcattaa atattggaac atataataac
      841 cagaacgaat atcaaagaag tatttcaaat tcacgatatg tttcattacg atagctaaaa
      901 atccgcttaa atggatctta tcaaataggt tagctacccc ccatttggca ccaatagaaa
      961 ccataaatcc ttgatagttt cctttaaatt tatgcttttc tccgcctttg atcgaagcca
     1021 cgatattcgc tgcggctgtg tgtcctgttt gttcagcagc ttgaacgatc tgcggtgtcg
     1081 gtgttcctgg gaattcttca taaaagacta aatcaccaat gatatagatg tttttatctt
     1141 cgtagccttt tgcctgcata tattcattgg cgatcaaccg ctgtccgcgt gctgattcta
     1201 atccaaagtc agcagcgtca gaagttcctt tgacaccagc tgtccaaatc agtgtgtgag
     1261 tcggaatgtt gcgtccgtct ttcaatttga tatgatcagc agccacttct acgattggtg
     1321 cattcaataa taattccacg ttgtgcttac gcaaatagcg ttcagctttt gcagcatcat
     1381 ttcgatccaa catattcaag atcgtcggca ttgcctctac gaccatcagt gtgatttcgt
     1441 ttggatctaa tttataatct ttggctaggc gatttttcca gtcgatcagt tccccaatca
     1501 tttcaatacc ggtaaatcca gaaccacaga caacgaaagt cagcatggct ttacgcagtt
     1561 catcatctgg ttccaatgca gcttttgcta ctgtcttctc aatatgttcc cgaatcctta
     1621 cagaatcttc aaatgaccaa agggtgaatc cgtgtgcttt gacaccaggt gtaccaaagt
     1681 cattcggctc tccgcccatt ccaaggatca gctgatcaaa aggataggaa cctaatttgg
     1741 tcttgacgat ttttcgttct ttatcgatac cgattacagt gtctgtgaca agttgtacat
     1801 tcttttgacg agcaaacaaa tgctgcagat cgtattggat tgcttctggt tctacacgtc
     1861 cgccagctac ttcatgcaac tcggtcatca tagtatggta cgaatgacga tcgatcagag
     1921 taattgctac atcttctttt ttcagtttct ttgccaagta ttttgtagct gaaacaccgg
     1981 catatcctgc tcctacaacg acaatatttt gctttgccat tgatcatccg ctccttatag
     2041 actatctata taatgaatat atgataattc ttttagtttg atacttatta cacaatctcc
     2101 atatattata tagatgttct gttcttttgt ctaactcctt ttggattttt ttcaaatttt
     2161 aaaataaagc gttttttcac gaaatttgct gaaagaaaac gtttgaaata ttacatgggt
     2221 tatttatcaa aaatagttga cttataggct aaaaagatta gaatgtataa tgaatcacaa
     2281 agaaaaattg tggactagaa atggaatggt ggggtattaa aatgaagaaa aaacgttttg
     2341 taactggatt tgccgtatta gcattttcag ctctagtgtt aggcgcttgc ggcgcagatg
     2401 acaacggaag ctcaaactct tcttctgaat catctacagc acaatcttcg actgcaaaaa
     2461 gcacaacaga atcatctgca aaagttgtag ctggcggaga tttgcaagac ggcacatata
     2521 aattagaaga aaaaaattat tcaaatggtt accgtgcagt ctttgaaatg gttgtaaaag
     2581 acggcaaaat cactgaatca aaatatgata acgtcaatga aaacggcgaa tcaaaaacaa
     2641 aagatgcaga atacaacaaa aacatggaag caaaatctgg cacaaaccca gaaaaataca
     2701 ttcctgagtt gaatgaccaa ttcttaaaag cacaaagcgc aagcggtgtg gaagtcgtaa
     2761 ctggagctac tcactcatct gaaagcttcc aaaactacgc acaacaattg atccaagctg
     2821 ctcaagctgg taacacagat acaatcgaaa tcgacaatgg tgctgatttg aaagacggca
     2881 cttacaagct tgaagaaaag aactactcta acggctaccg tgtgcaattc gaaatgacag
     2941 ttgctggcgg caaagtaact gaatcaaact ttgattatat cgacaaagac ggtaaatcaa
     3001 aacaagatga tacagaatat aatgaaaata tgaaagcaaa aagcggtaca gaaccaaaaa
     3061 cttacatccc tactctgaac gacgaattcg tcaaagcaat gggcgaagaa gatggctcac
     3121 ctgctaatgt agaagttgtt acaggtgcta cacacagctc acattcattc atcatgtacg
     3181 cacaacaatt agtgaatgca gctgaaaaag gcgacactca aacaatcgaa gtagataata
     3241 tcgtaacaga aaaataatca cataatcata ctaataaaag ttggagggtg ggacgatagc
     3301 cagattaggc agtcgtctca cctttcaaaa tgaagagagg aaaaagatgc ggaaaaaact
     3361 actattttcc ttaatcacac tgggcatctc ttttatggtg ctaactggct gcagcaactc
     3421 agcaaataaa acaaccactg aaagttcagc agctaccaag atattgaaag atccatattc
     3481 tgatgaacag ttcttgttag ggacttacgt tcgtatccgt gtgtatgatg aaggcaaaga
     3541 atcagcattg aaacctgcct tcgatcgagt aaaagaactt ggtgataaaa tcacgatcaa
     3601 tcaaaaaggt tctgagatcg atgaagtgaa tgagcaagct gggatcaaac cagtaaaagt
     3661 ttctgatgac gtctacacgt tagtcaagcg ggcctacgaa tatagccaag attctcaagg
     3721 cggattcgat atggcgattg gtgcaatcac acaattatgg cgaatcggtt ttgatgacgc
     3781 cagaaaacct tcccaagaag aaatcgatca ggcattgaaa ttagtggatt atcataagat
     3841 cgaactaaat gacaaagaaa aaactgttta tctaaaagaa aaaggaatga tcatcgattt
     3901 aggtgcaatc gccaaaggtt acattacgga cgaagtagtg aaagtcttga aaaaacaagg
     3961 agtgaccact gccatcgttg acttgggcgg taatgtctat gtcttaggcc acagcccaag
     4021 aggcgaaaac caagactgga cagtcggcat ccaagatccg aacatggctc gcggatctgt
     4081 tttaggttct attaaagaac ggaacaaaac attagttacc tctggaattt acgagcgtta
     4141 tttagaagta gatggcaaaa aataccatca tttgtttgat ccaaaaacgg gttatccgtt
     4201 cgacaatgat atcgcaagtg tcacgatcat aacagataaa tcaattgatg gtgacgggtt
     4261 gtctacagca gtcttttcaa tgggtgtgaa aaaaggactg gaatacgtcg aaagcgaatt
     4321 gaataacggg acggaagcga tcttcgtgac aaaagacgat aaagtatatg tgaccgatcc
     4381 aatcaaagac accttcaaat tatcggagga ctcccattac acgatgggtg accgttctga
     4441 actaaaataa ggagtacgaa ccatgacact aaaaatcttt ttagaagtag ttgaaatacg
     4501 aacaaaggtg gctagtgtat ttccttttgc ggtaggggta ttattctcta tcgctttttt
     4561 tcatgagata cattggctaa acactttttt attttttatt ggaatgctag tttttgattt
     4621 agcgactacc gctatcaata attacatgga ttatgaaaag gctcattctg aagtatataa
     4681 gtatgaagaa aatgtcattg gccgcagaaa tctatctcct gtattgattc gaaacatgat
     4741 tttagctatg attgcatttg tttttgttat cggcgttatt ctaacgatca atacgggttg
     4801 gcttttactt ttgatgggat ttatctgttg ttttattgga gtattctata cattcggacc
     4861 gattccttta tctcgaatgc ctttagggga aattttcagt ggggtgacta tgggccttgg
     4921 aatttttgcc atggtcgttt atgtcaatac attcggttca gatgtctatg atctgacagt
     4981 caacttttca tctggacaat ttgatttggt aggaaatctt tgggctatag cagcaatcgt
     5041 attagcttcc ttacccttgg tgtttacgat tgccaatatc atgttggcta ataatttgcg
     5101 ggatcttgac cgtgatattg aaaatcatcg ctatacacta gttttttata tcggacgtcc
     5161 tgcgggaaca gtcttattcc agctattgat gtatgcttgc tatttcgtga ttttaatggg
     5221 gttgttgagc ggtatctatg aatggccgat cttggtcacc ttcttgacct tgccaattgt
     5281 gaagaagcat ttggatcaat tcaagcaaac gttaccccag cctatcagtt tcagctattc
     5341 catcaaaaat atggtcttat tcaatgccag ttatgtattg gggctattac taacaatcat
     5401 tatgcaagcc atttaacagc atgaagaggt tgtgaaaaaa ctgccctgca tcaagtaata
     5461 agaacagcca aataaaaata gctccttata tttttcgttt ggttgggctt attaccgcag
     5521 atgcaagctt ttgaacaccg tttatcagga ggttgtgaaa aagtcgctta gtttcgagta
     5581 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaatttgg cttaataccg
     5641 agaaactggc ttttgaacac cgtttatcag aggttgtaaa atcagtgttt tgtcctgagt
     5701 attagagaaa caaatggaaa aatagttcct catattttgc cgttttttga gctaataccg
     5761 aaggacagct gattgaacac tatttgttcg gaaaaagtga ctaactatga cacaattttt
     5821 ttcacagtcc cttttttcac ttgatttgat tcgtaccagc gaacttgacg agaactttct
     5881 tggtttggta actatatggt attcttttaa catcctcgtt tgcttcttct aatttattta
     5941 tacaaagtca cactttttta aacatctgtt cttcgataca tttctatttc ttttaaacat
     6001 cgataccaat attttgaact taagagtgca taccaaatgg attcatttac tcttcgtcag
     6061 ttacgaagat aatcaaaatc tccaacttcc ctacttattt cgttttgaga attatcgaag
     6121 caatcttaca taaataacta aaaaacaaaa aaccagaaaa tcagtatact gattttctgg
     6181 ttttacatgg tttgttcaat aaaaagctgt tggaactgtt aatattaaat tatcgcatcg
     6241 ttacgaattc ttccgctcct gttggatgga tggctactgt attgtcaaag tcttctttag
     6301 ttgcacccat cttgatagcc acggcaaaac cttgcagcat ctcatcgaca ccaacaccaa
     6361 tagcatgtaa gccgacgatt ctttcttctt ttccgacaca gatcaatttc atttcgcatt
     6421 tttggcgata atcatttaat gcaaagtaca ttggggtaaa gcgtgaacga taaactttca
     6481 attcattttc gccatatttt tccaatgctt cttcttctgt caaaccaatt gttgcaattg
     6541 gtggatgcgt aaagacgact gtcggaacaa gtttatagtc aagataagaa tctttctttc
     6601 cattaaataa acgttctgat aaacgtctac cagctgcgat tgcaacagga gtcagatcta
     6661 atttaccgat cacatcacca acagcaaaaa tatgttcatc cgttgtattt tggtatttat
     6721 ctactttgat aaaccctttt ttgtccaatt ccacatttgt attttccaga cctaattttt
     6781 cggtattcgg tacacgtcca ccggcaaaaa gtacacaatc accagttaag gtttcaccat
     6841 tttcaaatag caccgtatat tcgtcattgt ttttagtaat ttctttagca atatgatgtg
     6901 cgtaagtttt tattccagct tcttggtaca tttggatcaa attgtccgaa agcattttat
     6961 caaacgttct aagtggtcgt tcttttcgat atgcccacat gacttcacta cctaaaccac
     7021 gaaatacacc tgaaagttca gccgcaatgt atccagcacc taaaacgatt gctctcttag
     7081 gtaactctgt taattcaaaa aatccatttg aatcaattgc gtattctcca ccaggaatgg
     7141 tcattttact tgcacggcct ccagtagcga tcaagatttt aggagcacga taggtttcac
     7201 cgtttacttc gatcgtttga ctatcgataa aagtagcgta accttttata gcctcgacat
     7261 gattgctatc taatcctctt tgataagcac cgtgtagaaa atcaatatat ttttctcgtc
     7321 tttctactag accggcgaaa tcaacatttt ttaaatctgc ttggataccg taacttgagg
     7381 catctcgttc aattgtttcc aaaatcgtac ttgcttgcca cataactttt ttaggtacac
     7441 aaccgacgtt gacacatgtt ccgcccaatt cattcgcttc aatcagcaaa acttttgcgc
     7501 catgcatccc tgctctgttt gctgaagcaa taccgccaga gccgccacca attacgatgt
     7561 aatcatatat ttgcattttg ttcctcctta ttgaagagat caatcaaaac ctttatttaa
     7621 cgatcctttt tctacagaaa acaagtgtaa cacttttctt gaattttgta tgcgaagatg
     7681 cttaaaacag ggatatatca gctttttcct tatttacgtt ttcggatcat atctccaggt
     7741 ttcaccggct gtgcgactgg catagttaaa atcatcattg gatttggtgc tcggtcaatg
     7801 gattcgcctt cttcattatg cataacttca acggtttgac tgaaatgact gaatcctgga
     7861 ccataaaatt cgatttcatc tcctacagaa aacaagtttc tctgacgtat cgtagcaatc
     7921 tgtgttgcct catcataaga taatacttca ccgacaaatt tatatactgg gattttacga
     7981 cgttcaccga ataattgttc gttttcagtt ggtgtattgt agtaaaaacc tgtagctaat
     8041 tctcgttgtg ctactttcca taactcgtcg atccattctt gcttgcagac atagttttca
     8101 ggatcttcca tataactgtc tacagccgct ttatagacat ttgacaccgt agatacataa
     8161 tggatcgatt tcattcttcc ttcgatcttg aagctgtcta cgccgttttc aatcaattct
     8221 ggaatatgtt cgatcattga catatccact gcactcatcg agaattcttc ttccacttcg
     8281 cctgtatcag ttaaactgtt tcgttcttga ccaaaaggca tatcgaacaa tccatacttc
     8341 cagcgacaag attgagaaca tccgccacgg tttgcatccc gcatcgacat atggttggac
     8401 aatgtgcatc gaccagaata agagatacac atggcaccat ggataaatgc ttcgatttcg
     8461 gtatccgtat ttttacgaat ctctgccact tcctccattg aaacttcacg agctaaaacg
     8521 acacgttcca acccttcttc tttccagaat tccaatgtct caaaattagt tgctgaagct
     8581 tgagtggata aatggatcgg cagacctggg gcttctgtcg cacaaatttc gatcaaagct
     8641 ggatcagaaa caatcactgc agaaataccg acatcacgca aactgcggaa aaattcccct
     8701 gctccatctt catttccttc atgggtgacc atattagcag caacgtatac cttcgcatca
     8761 tgttcttttg caaaagcaac tccttcagcc atttcttcat aagtaaaatt acctgcacgg
     8821 cttcttaaac catatgcatt cccgccaata tatactgcat ctgctccata atggatcgcg
     8881 gtttttaact tttccagtgt tcctgctggc gctaggattt ctggtcgttt caattttctt
     8941 tttactgtca tttctttcat catactcctt atttgatagc agaaggatca atataaaaga
     9001 atcctgtatc taattcacgg ttttcaggat gcaatttact gatttcgcta gtcatttttt
     9061 ccgctttttc ttgatcccag ctaccttcta aaatttgttt ttttgcttcg gcgaatagtc
     9121 gagtgatgtt tacgaatttt tcgcctggag taaataatcc gtccaatttc catgtacagt
     9181 aatgatgctg ataaagttca ttcaattcat tcgagagatt cagatcattg ctggcaaaaa
     9241 tatgtgtgcc atgactatct tcataaatag aataatgtgt ctcttctttt ttaggttccg
     9301 agataaaaag acctctttca cgatcttttt gttcgtcttg tttcgtatag ttatagtaat
     9361 tctgtagcag tggacgtttg gattgatgga tgcatgtagc accatacaca agggtttcta
     9421 caggaatatc gagtttttct tccatcgcct tcatctcttc aaaaggaact tcacgagcaa
     9481 gtactgctcc aactgcgcct tttttcgccc agaaattgat ttgacgtgcg ctcgttacta
     9541 atgtttcagc atcataaata tacggtatac gcaattcagg attttttttc atcgtataaa
     9601 taatacctgt atcaccaact gtgatcacat ctacgtttat ttcttttaaa aaagccaaat
     9661 attcaggtac atttttcatt ttttcaggat gaatgatccc atttacagca atattcgctt
     9721 ttttaccata cttgtgtgct aattctacca attgtcgctg ttcttctcgt gtaaatgaag
     9781 caggcagacg caatccaaat tgctcttcac cgaaatatag tgtatctgca cctgcagcaa
     9841 gtaactgttc tgcttgttca atagtttcta ctgtggttat gagttcgatc ataattttct
     9901 cctcctacaa cttcataata gtagcatagc tctaaaaact ttccaatact tcttctattt
     9961 aaagtcggat ttttgaaaat tatttcacaa aaaatcaaaa taaagttcga tatattctgt
    10021 ccaaatataa aaagagattg tgacaaaaat cttgtcacaa cctcttaatc aagtcttact
    10081 attataaaaa ttcagctaca caggccaagt aactataggg aacctactgt ttccttttta
    10141 ggtccgcgaa cattcaatgt gatcttacct tttgaagcac ctactgttac gtggtcacct
    10201 aaacgaattt ctccgccaag caaagcctcg ctcaatcgat cttcaatttc tttttgaagt
    10261 gcgcgacgga ttggacgtgc accatattca ggatcaaatc cagctttccc gatcacatcg
    10321 attgcagatg gtgtgatttt cacttgaata tcttgttctt tcaatcgttt gataatcgct
    10381 ttgctcatga tttggacgat tgtatggatt tcatctttac tcaatgaatg gaagacgaca
    10441 gtctcatcga ttcgattcaa gaattcaggt cggaaagctt tctttaactc ttctaagata
    10501 cgtttttgca tggctttgtg atctttagta acatcttgga cattgaatcc gacatttttt
    10561 tcttctcgaa tttgtgtcgc tccgatattt gaagtcataa tcatgattgt atttctaaag
    10621 tccacttttc tacctttaga atctgttaaa tgaccatcat ccaatacttg cagaagtaaa
    10681 ttgaaaacgt ctggatgtgc tttctccact tcatctaaga gaatcactga atatggtttt
    10741 tgacgaattt tttctgtcaa ctgtccacct tcatcatacc ctacgtatcc tggaggagac
    10801 ccgattaatc ggcttgtact gtatttttcc ataaattctg acatatcaac acggatcagg
    10861 gcatcttcac ttccaaacat gacttctgaa agtgctttgg ccaattctgt ttttccgaca
    10921 ccagttggtc caaggaacat gaatgaacca attggacgat caggatcttt caatccgctt
    10981 cgtgcacggc ggatcgcacg tgaaactgct ttgacagcct catcttgacc aacgacacgt
    11041 tcatgcagaa gtccttccag ttctaacaag cgttcgcttt cttttttctc caactgctgt
    11101 agagggacac cagtccactc cgatacaact gtagcaacat cttcttctgt tacacgatca
    11161 gaataacctt gctcctgttt tgcttcaatt gcagaaactt tttgcagctt tttacgtagt
    11221 gctttttctt gtctgcgtaa ttgagcagca ttttcaaagt cttgtttttg gatcgctgct
    11281 tccttttctt gtactagttc atcgatttct agtttgatca cagttgattt tgttaagtga
    11341 tcggtttgat ccaaacggac tttcgctgct gattcatcga tcaaatcaat tgctttatcg
    11401 ggtagttgac gagaagtgat ataacgaaca gaaagattga ctgctgctcg tacagcttca
    11461 tctgtgatct ccactccatg gtgctcttca tatcttgtac gtaatccttg aagaatcact
    11521 tctgcttctt caggagttgg ctcatctact tgaatgcgag caaaacgtcg ctctaatgca
    11581 gaatcttttt cgatatattt ttgatattca tctagggtcg ttgctccgat cgtttgtaat
    11641 tctcctcgag ctaacgccgg tttcaagata ttcgaagcat caattgctcc ttctgctcca
    11701 cctgcaccaa ttaaggtatg caattcatca atgaataaga ttacttgacc atcattatag
    11761 atttcgtcga tgaccttttt cattcgatct tcaaattcac cgcgatattt cgtaccagca
    11821 accaaagatc ccatatcaag catcatcagg cgcttttctt gcatgtcttc tggcacttca
    11881 cctaaaatga ttttttgagc taacccttca gcaatggctg ttttgcctac accaggttca
    11941 cccaccagta cagggttatt ctttgtccgt cggctaagaa tctggataag ccgtttcact
    12001 tctctcgaac gaccaacaac tgggtccagc ttgttttctt ttgctaattt cgtcaaatca
    12061 cgtgctaatg aatctagcgt aggtgttcct tgcggtgttt gccgtttatc ttgtacattt
    12121 acatttctac gacgattcat tccttttcca gcagaatcac cagctagccc cattttttgt
    12181 ttcagaactt gacgggcttt tgaaaggctg atacctaagt tgatcatgat tcgagtagcc
    12241 atgatacttt catcttttaa taagctcatc aaaatatgtt ctgttccaac tttttgagaa
    12301 ccagttttct tcacttcgct gctagctaaa gcaaaaactt gtttcattct tggtgaatat
    12361 ggaagaaaga ctcctttagg gtaagaacgg ataccaccat aaccaatcag atgttcaatt
    12421 tcttcataaa tttccgtttc attcaaatcc atttcacgta atacttttcc agcaattcca
    12481 ttttgctcga ccactaaggc tagtaaaaca tgttctgaac taactgattg atgtttcaac
    12541 cgttttgctt cttcttgtgc aatttctaat actgcttggg ctctttcagt aaaaagttct
    12601 tccatctaat ctcacttccc atcttcataa cttaaacgtt ccagaaatgc tcggagaatc
    12661 cgagcacgtg tatgatcttc atattcattg aaattcaatg tgttttttgc aattgcactc
    12721 aacatcaagt ttccttcttt ttttgtaatt atttggtctt cataaagttt ttgaataata
    12781 gcaaaagcat ttttctcact gattgtatca tcaaataact gatttatctg ctcaagtaat
    12841 tgttttttat ctgaaatcct tacttttgca attcgtatat aaccaccacc accacgtttg
    12901 ctttctacta gataaccacg ttggatggta aaacgggtat taatcacata gttgatttgt
    12961 gaaggaacac agttaaagag gtctgccatt tcaatccttc gaatctcgat catttcacta
    13021 ttttccagaa ttttctttat atatgattca attaaatccg aggtattctg atgtgccatc
    13081 ttattcattc cctttgacta atattgacct taattataac gaatttgata atagaaagaa
    13141 agaagaacgc tttttgttaa ataaatcctt tagaatcaac aaaaaaaaat acggaatata
    13201 ctattccgta tc
//
LOCUS       DAKCAA010000068        13016 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000068 DAKCAA010000000
VERSION     DAKCAA010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.069"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            414..947
                     /locus_tag="OUE31_002216"
     CDS             414..947
                     /locus_tag="OUE31_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HCU0223198.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(1437..1961)
                     /locus_tag="OUE31_002217"
     CDS             complement(1437..1961)
                     /locus_tag="OUE31_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0223199.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(1954..2427)
                     /gene="tsaE"
                     /locus_tag="OUE31_002218"
     CDS             complement(1954..2427)
                     /gene="tsaE"
                     /locus_tag="OUE31_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HCU0223200.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(2550..3530)
                     /gene="pta"
                     /locus_tag="OUE31_002219"
     CDS             complement(2550..3530)
                     /gene="pta"
                     /locus_tag="OUE31_002219"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HCU0223201.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(3683..4363)
                     /locus_tag="OUE31_002220"
     CDS             complement(3683..4363)
                     /locus_tag="OUE31_002220"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCU0223202.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            4489..5358
                     /locus_tag="OUE31_002221"
     CDS             4489..5358
                     /locus_tag="OUE31_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCU0223203.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            5384..5899
                     /locus_tag="OUE31_002222"
     CDS             5384..5899
                     /locus_tag="OUE31_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223204.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(5946..6539)
                     /locus_tag="OUE31_002223"
     CDS             complement(5946..6539)
                     /locus_tag="OUE31_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0223205.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(6564..6743)
                     /locus_tag="OUE31_002224"
     CDS             complement(6564..6743)
                     /locus_tag="OUE31_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223206.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(6820..7329)
                     /locus_tag="OUE31_002225"
     CDS             complement(6820..7329)
                     /locus_tag="OUE31_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223207.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(7425..7805)
                     /locus_tag="OUE31_002226"
     CDS             complement(7425..7805)
                     /locus_tag="OUE31_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCU0223208.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            8135..8884
                     /locus_tag="OUE31_002227"
     CDS             8135..8884
                     /locus_tag="OUE31_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HCU0223209.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKLTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(9068..10345)
                     /locus_tag="OUE31_002228"
     CDS             complement(9068..10345)
                     /locus_tag="OUE31_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223210.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(10424..11068)
                     /gene="pcp"
                     /locus_tag="OUE31_002229"
     CDS             complement(10424..11068)
                     /gene="pcp"
                     /locus_tag="OUE31_002229"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HCU0223211.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(11267..12211)
                     /locus_tag="OUE31_002230"
     CDS             complement(11267..12211)
                     /locus_tag="OUE31_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HCU0223212.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(12213..12899)
                     /locus_tag="OUE31_002231"
     CDS             complement(12213..12899)
                     /locus_tag="OUE31_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HCU0223213.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3761 a         2715 c         2301 g         4239 t
ORIGIN      
        1 cttattaccg cagatgcaag cttttgaaca ccgtttattg agaagttgtg aaatcagcgt
       61 cctgacctga gtattagaga aacaaatggc aaaatagttc ctcatatttt gctatttttt
      121 gagctaatac cgagggtcag ctgattgaac accgtttagt ggagaagttg tgaaaaagtc
      181 gcctactttc gagtcgtaag aaattttttt gaaaatggtt cctcacaact ttgcataaat
      241 ttgacttaat accgagaagt catgatcccc atctaactcc aaatcacaag gaatgagttc
      301 aaaaactagc ttttctcaac aaatattaca taaaaaattc tatgtttttt gttaaattta
      361 tttgcttttt tcaaaagtat gttacagtaa tttcccaagg aggttttaca gaaatgaatt
      421 ttgttgccat ggattttgaa actgccaatc atcagcctta tagtgcttgt tctcttgcgc
      481 tagtcatggt aaaaaatagc cagatcgttg atgaattcta tacattgata cagcctgaga
      541 ctcctttttt ctggcgaaat gtccaaattc acggaatcca tcaagaagac gtacgcaatg
      601 cgccgaaatt cccagaagtc tggcaaacta tccaaccata ttttcaaaaa aatcgtttag
      661 tcgttgcaca taatgctgct tttgatacaa aggtcttagc gggatgctta gattattatc
      721 atcttgaaca gcctaattat ctttctttat gtacagtgaa aagtagccgt cgcctgtttc
      781 ctgaatttcc aaatcatcga ttgaacactg tgtgcgaaaa tttgaacatc caattagatc
      841 atcaccatga tgcattggaa gatagtcgtg catgtgcgga aatcctgctt tatcaagaaa
      901 aaaaattcgg gacagatcca ttgaaaaaac ttgtgactat aaagtaaaag aatacttatg
      961 aaacacacaa agaggtcgtg agcctgccgt ttcactccga gtcacaagga gcaatttcaa
     1021 aaaatagctt ctcatgttta ttaaatattg tgactggtga ccgaggagct ggcaggagaa
     1081 caccgtttat tggagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
     1141 acaaaaatag cttctcatat ttttcatttg gttggactta ttaccgcaga tgcaagcttt
     1201 tggacaccgt ttaccaagag gttgtgaaat cagcgttttg acctgagtat tagagaaaca
     1261 aacggcaaaa tagttcctca tattttgccg ttttttgagc taataccgaa ggtcagctga
     1321 ttgaacaccg tttattcaaa aaaaatggac tgcgacacga cttttgtcac agtcccttcg
     1381 tgtgtttttc tgccttctca aaaggatgac agtttctcac tcttttccta tttcttctat
     1441 tcaatcaaat aactcatttt atatacatct aaaaattcac ctagatctgt tcttgcccct
     1501 ctaggcatga ccgcttcgat ttggaagccc atttttcggt aaaggtgtac ggctctttca
     1561 ttacgaactt gaacgtcaag ctccaatcga aaaagtacac ccatttcctt cgcccaactg
     1621 atgatttctt ctagcataag agtgcctagt cccattcccc aatattcctg cagaatactg
     1681 ataccgactt ctcccacgtg agacaaacga aattgactgt ctgccttgac agatgctgtt
     1741 ccaataatcg tcccttcata gattgcaagc agcaataaat tattattgct ttcgtatata
     1801 taatccaact cttcttctaa ggtttctggt ggtaacagga gttctgcttc atccaaaact
     1861 aaaaattctg tctccttatt aacttgtccc atcatcaaaa gaatgtcttt tgcatctcct
     1921 ggcactgctt cccgcaagat gatcccaact tcttcactca tgattttcag cccatttttc
     1981 tagaattcgc tgtttgaagg tttcactttg ctccccgtat gagattagtt tcacataccg
     2041 cttttctaaa tctgtatcac ttttttctaa aatcagttcc aaataatcct ccggcagtgc
     2101 ttcttctaat agatttcccc attcaacaac ggaaagccca tcaccttcaa aatattcatc
     2161 taaccctaaa tctgctccgc tagctgctac ccgataaata tccatatgat acaacggaat
     2221 ccgaccttga ctatattctc taataatcgt gtatgtcgga cttttgatca tttgcgttat
     2281 ccctaatcct tgggcaattc ctttcgtcaa cgttgtttta cccgcaccta gatcaccagt
     2341 caatatcaga ttgtcacctg gcattgcgga atgaccaatt gcctctgcga attgttctgt
     2401 cattgttaat cctgatagtt cgatcatttt tcatcttctc ccgctcttct ttctttttgc
     2461 cagtatatcg cgtaatgaag tttttttaaa gaaaaaatga actagtcaag aacagcagct
     2521 gctgtttttg gctagttcgc gtgtatttgt taatcaatca atgtttgtgc tgctgtgata
     2581 atcgataatt tatatacatc ttcttcattt gctccacgag acaaatcaga aaccggtttg
     2641 ttcaagcctt gtagaattgg tccgattgct tcaaagttac cgaaacgctg agcaatttta
     2701 tagccgatat ttcctgactg caattctgga aatacaaaga ctgttgcttg accagctact
     2761 tctgaatctg gcgctttcag ttgtgcaact gaaggaacat aagaagcatc aaattgcaat
     2821 tcgccgtcga tcatgtattg tggcgctagt tttttagcga ttttagttgc ttcaactact
     2881 ttgtctactt ctggcgattt cgctgagcct tttgtcgaga agctcatcat tgctactttt
     2941 ggttcgatat cgaacaattc tgctgttttt gcagaatcta cggcgatttc agccaattct
     3001 tgcgcagttg gattcacgtt gatcgcacaa tccgaaaaga catatttttc ttgatctctt
     3061 ccacgtacca tgatcatcgc tccgcttgtc cgactgatgc caggctttgt tttgatgatc
     3121 tgaagtgctg ggcgaacagt gtcgccagtc gaatggatcg ctccagagac cattccgtct
     3181 gcaatcccca tatacgtaag catcgtacca aagtaattca catcttttaa aatcttttct
     3241 gcttgttctt tggatgcctt tccatttcta cgttcaacaa aagtatccac catttcatcc
     3301 cacttatcgt aattatcagg gctgatgatc gtaaagctag atgttttgat tcctctggca
     3361 tgcgctgcat ttcttatttc ttcttcgttc cctactaaaa tgggttccac aagttcttct
     3421 gctttcaacc gggcagctgc gcctaaaata cgagcatcag tagcttccgg gaaaacgatt
     3481 ttgatcccac ggcgaacaat tttaaatctt aaactatcaa acaattccac aagatgacct
     3541 ccagacgttt ttatatgtat tatcatacac tattccagaa aaaaagaaca gtttatttta
     3601 tctgtatcag tcaaaaatgc tggaaaaatt aagtttttca catacaaagc gaactgcact
     3661 ataacaggaa agcgctgttt tattacactg tttcaggcag ttgccaatca atcggttctt
     3721 ctcctaacgc aaggagcgca tcattcgttt tcgagaaggg tttggaacca aaaaagccac
     3781 gacttgcaga taacggactg ggatgtggag atgttatgat gatatggcga ctcttatcga
     3841 tcattttgat tttttcttgt gccggttttc cccacaagat aaacacgatt ggtttttccc
     3901 gttcatttaa tttttcaatg atcgtgtctg ttaatctttc ccaacctttc ccgcgatgag
     3961 aatacgcttg cccttcccga acggtaagaa cggtgttgag taaaaggact ccctgtttag
     4021 cccatgacac tagatttcca tgttgaacag gtgcgattcc aagatcatca taaagctctt
     4081 tatagatatt tcttaacgat ggcgggatct ttacgccagg ttgcacagaa aaagataagc
     4141 catgagcttg attttctcca tgataaggat cttgtcctaa aatcaccact ttaacttctt
     4201 cataaggagt caattccaat gcttcataga tatgatacat atctggatgg atcttttggg
     4261 acgcatattc tttttttaaa aattctctta gatgcagata ataatctttt gaaaattctg
     4321 aggacaaaac ttcttgccaa ctgttatgaa tgatttcttt caaaaactcc acctcctaat
     4381 aaaaagaata actcacattt tcttcaatca caagggacaa tcttcaccct cagcacttga
     4441 ttaatatggt aaactaggaa caagaagcag aaaggaacga taatcattat gatcaaatta
     4501 attgcatcag atatggacgg cacattatta gatgcccata tgagtgtttc tcctgaaaat
     4561 gccgaggcga tacgttttgc aaatgatgcc ggtgttgagt tcatggtcgc tactggtcga
     4621 aactatcaag aagctcgcgc agctttagat gaggtaggaa tcgattgtgc gatgatcact
     4681 ttgaacgggg cacaggtatt tgataaagaa ggaaattcat tgtttaccgt gtcgattcca
     4741 aataatcaag caatctctgt tttagatatt ctagatgcta acggtattta ctatgaagta
     4801 gcaaccaacg atggtcttta ttctgaaaat caagcgaaac gaattgaaag ttttgcttcc
     4861 atggtggcta cccatttacc tcaccttacg tataaaatgg cgattgccat ggcctcagct
     4921 aagctggagt tattgcacat cacatacgtg gacagtattc gtgctatttt ggaagaaaag
     4981 aatctggaag ttttaaaaat tatttgtttt catacagaag ggccagctgt attaggtcca
     5041 gttggaaagc agatttctct tttaggcgat ctagccgtta cttcctctgg tcaaaacaat
     5101 atcgaagtga accataaaaa cgctcaaaaa ggaattgctg ttgcccatgt cgctcacgag
     5161 cgtgggattt ctttagaaga agtcatgacg attggcgata acttcaatga tgtcagcatg
     5221 ctgcaagtag caggagtcag tttcgcaatg ggaaatgcag aaatcgaagt aaaagattat
     5281 gccaaatata caacggacac aaaccttgaa tctggcgtag gaaaagccat attgcgcgcg
     5341 attgcagaag acttgtagtt ttatctagaa aagagggata tagatgtcag aatttttcat
     5401 tcaggaaaag cagcttggac gtgcaactcg gacaattgtc aaaaacgaaa aaggacattc
     5461 cctgtttttg atggttggtc gctggggaac aaagggcgat gcattgtctc tttatgccat
     5521 gaatggcgat ctcgttgctc acatcaagca gataagcctg acattcggta cgcgttttga
     5581 gctgtataaa gagttcgaaa aggtgggaac catgcagaaa atattcaatt ggcccggtga
     5641 cttttattat attcgtagac ttcactggac agtccaaggt gatatctata atcatcaata
     5701 tcaaatccat catttcaatc agcaaatcat gaaaatggat aaagcaacac ttttttcagg
     5761 agattactat gtattggatg tctcaaatga tgaagatgct ccagtttgta tttgtattgc
     5821 tgcggtttta gattactggc tctaccgtaa agacaaaagt cgcgataagc ctgtttctta
     5881 ccgacttaac ttaagttaaa aagatgtacc tgaaatgcgg aaatacgcat ttcaggtaca
     5941 tctttttaga tattcttttg catatgatca taaagatgac cactgatcat ccgctgaccg
     6001 acaactttga agtcatggcg ttcgtataat tttttagcct ttggattttt ttcatccaca
     6061 cttagaccga tgacggagcg attagctttc ttcgccaatt taggtaatgc ttctaataat
     6121 cgcgaaccga tgccttgtcc tctaaaatct tctgatacac tgatagagtc caaataccat
     6181 tcgttgggaa acgtttcttt atcaatgaac aaacgtgtag acgcatctag ctgatatttc
     6241 tctaagatag gtaccagtgg ctgatcgatg attgattctt cttcatctgt ataaccgtaa
     6301 gcaactcctg caactttacc gtctatttct tctacgatac ctcgtgaata actgtaacga
     6361 taatttggat cagtgattgc ttcttctaaa atctctaaag tcttttgttc ccctgtctgc
     6421 ttcaaaaatg gcagttccat atcttttaga atcactaaga tcaatggggc gatttctgga
     6481 gcatcttctt ttctcgcaaa acgaatcata gtttcctctc cttttctcca ttctaacatg
     6541 cagaaaaaga aatcgcaaaa tcgttatttt aaaaaatctt caatcttttc agtaatgaaa
     6601 taaccatgag taacgattct tgccgcttca gttcggcaat aagggcagac gactggcatt
     6661 tctttatcat tatgttcgac tacattattg acttcttcgt atgcaaattt ttttccgcaa
     6721 ttagggcatt tcattttttc catgttatct caacttcctt tcatctttac tctcttagct
     6781 tactcttata ttgtaaaaaa gagaagcaat atccttcttc tatgcagata tccatacctg
     6841 acggtcctgt tctccatcta ttaatcggac tttataataa ggacgttcat ctttgactag
     6901 aagtgtccac tctttcactt ttgctttttt cccgtagtag ctgactgctt ccttcatcgc
     6961 tgcttgcggt tgtttgaact cttccgtttt ttctatatca aaaagatgtt ctgcggcctt
     7021 ttccgtgtca tttcgtacgg ttgttttccc agtggatgga ttgactgcta tgacttgtcc
     7081 ttcacaaaaa aactggtatt catatgttgc attcgtagga ttctccaaat ctttttcaac
     7141 tgcaaaatga atagcagata tgttatgttc ttttgtttcg ttttttacga ttgctgctgc
     7201 ttttttcaat gagatccgat attcctggtc actaatatca tccatgtgaa aagcggcatt
     7261 gagcagtccc gtcataccgg taatccctat tacgatgagg gcagcaacac caaacatcat
     7321 ttttttcatt cttcattctc ctgtttcttt tttttaaaga atatcaagaa atgaacgaat
     7381 gaaaaatcga atgaaacgaa aaaaaagtga caattttgtt atctttattc gtgcagttct
     7441 aatggcaatc cgtctggatc aaagaaaaac gtcatttttt ttcctgtaaa ggtatcttct
     7501 ctaatcggtt ctgattcgat ccctaaggac tgcaattctg caattgtttc ttcaatatcg
     7561 tctactttga aagcaagatg acgcaagcca caagcttctg gatagtttgg tcgttgtggc
     7621 gcattagcaa ttccaaaaat ctccaattca gcacttccta gtttcagatc taatttatag
     7681 tcatctcgtt ctttgcggta attttctctg attacttcaa atcctaattt attaacataa
     7741 aaatcacgtg atttctgata atctgaaaca atgatggcta tatgatggat cgttgtaagg
     7801 ttcatatgag cactcctatt cttcgtttaa gctcggatct atattaatct ccagttccat
     7861 tgtaaatgtg tcagattgaa aaaaatagct gtttttcctt tttataagaa aaaaggcaaa
     7921 aaaaacagaa agtaggtcct ccaagacact cttcctgttc ccaatataat aaatgaaagt
     7981 aagaaattat attttcaaga aaacaaacag aaaattatca taacacaaat tatttataat
     8041 tgaaagacta gttttttttc aagaaaagca tacaatagat tgtgttagta aatacagaac
     8101 acactacatt tagtgtctta aggagtcctc atacatgaag tcatattttc agtttttagc
     8161 tcatcagcta aaaggctggc cgcaacaaaa ttattatctt ttctttttca gtcttggctg
     8221 ccaggtcatg actcttgtca atagtcccat cacttggctg tccgttatta catttatcgg
     8281 taccacgctt ggtgtattgt gtattttatc catcaatgcg gcaaaatcag tcaacggtat
     8341 tttaggtatt ttgtctgcga tttgttttat tatcgttggg ttttcagcaa agaactattt
     8401 aagtatcggt gaacagattg cttatatgat cacattggat atccccgtat tgttaagtaa
     8461 agaatggaat cataatatgg cttcaaaaat ccgaaaatta actggaaaaa gctggtttat
     8521 cgcaatcatc agtactttcc ttgtctatct tgtttcagga ttcctgattg gtcgttatac
     8581 agatgatcct cggccgtggg tagatgccat tgctttttct attagcttga ctgctggtat
     8641 catcagtttc ttgcgttaca acaaccaata ttactggtgg ttagcttcag ggcttgctca
     8701 aatggtcctt tggtatattt catttacgca tggatctgca agtttggcga tgttcgtgaa
     8761 cagctctgtt tacttgctga atgatgtcct tgcatttacc gtttcacctt ggtataacca
     8821 aaaagaacgt gaacgtatgc aaaaaatgga agaagaatac tacaacgcac aacaacacgc
     8881 ataaaaaaac tgagcgtggg acaaaagtaa agaacacttt tgtctcacgc tctaaacacg
     8941 tataaacggc ggaatcagaa gcaactcctt cggaaataag ctgaaattca caaaaatttg
     9001 aaaagcaatt ttcgtgaatt tcttcttatt tcttggagtt aaacgcttct gtcccagcct
     9061 ctatttttta tagtaattcc ttcagatact ttcttgcctc atcattgaaa cgcagtgatt
     9121 cttctaactt ctgataatat tccaacgctt gtttctgagc ttcagtaaaa cgataatgtt
     9181 ttcctttcca tttgtcgatt gtctcttgca catttccaga ttggatatct ttcactacta
     9241 gttgccattt ttcttttgag actgtacggt ctttcttatc agcagattgt atagcttctc
     9301 gttctttacg caatactttt aaaaaaccat ttctgactat ccgaggaatg ctgtcgaaga
     9361 acccttctgt aaaaccatag cgacaatatt gcttccaaat aaatagatag atttttggtt
     9421 ggatgaatcg ttggtttttc gcaaaatatt ccatctgagc agtgacttct ggtgttcgtt
     9481 gacgttttgt ctttctcaac acggaaataa atgtttcaaa ataagcatta ggatgtactg
     9541 gcacttcttc atatacgatg gattgccaat ctttacgtaa aaatgcgcga tagttgatca
     9601 agaattcttc tacatccttt actaattctt ctgcaaagtc gtcaaatagt tcttttttta
     9661 tctgtcgctt ttttgactgc ccattgatgt gttcacttat tttcttgatt tcattttcca
     9721 atgcttgata atccgctatg taaatcggca tttctacttg gcgaaattct gcgagccgct
     9781 gagctaattt tatatccggt aaatatggct gtttcatccg acgattttgg tacaagacaa
     9841 aacagtattt ttgccatagt ccttcaggaa aatcgatatt cttctgctta agccataata
     9901 attcgtctaa ggccagatca acttttgtca ttccctgatg gatcgaagct gccactgtcg
     9961 gagagacatg caggtgatcg gcaaagtggt tgatgcctag ttttaggatc tttccggttt
    10021 ttggcgattt aacgatgtat tgcactttta attctctacc acactcacaa tacaattttt
    10081 gctggcttcg ttttgttcga aaaaacggat tgatcttgaa gtcagaaaac acccaatctg
    10141 ttgcagctaa ataatgttct tccataaaac gagagctgat tagatatcgg cggtgcttat
    10201 cgactagttc ccgctgtttt ttcgttaatt ttgcatagat ctcccaacgt tgactgcttg
    10261 tgtattgttt agaaattttg atgggatagc ttttgctgat ttcttttgga aaccattctt
    10321 caaagacgga ttgccattct tccacggctg tttctttcct ttctaattac aaaaagctgg
    10381 ctactaacat aacgttagca accagccagt gtttcttgct aaattagtga gttgttccgg
    10441 catttccgga aatatcttct ttattttcta ctgctgcttc aactgcataa gtcaaagaag
    10501 aagcaatgtc ttctaaagac atagaaggcg tacccactgg acgatcgatc acttgatcgg
    10561 gtgagaatgg cacgtggatg aacccacctc gaattgccgg gaattgtgtt tcgatcaaat
    10621 gaagcaaacg atacatgata tcattgcaga caaatgttcc tgctgtataa gagatgtacg
    10681 ctggtagacc atgatcttgt acattttttg tcattgcttt gattggcaat gaggtaaagt
    10741 aagcggctgg accgttttct tctaaagccg tatcgaatgg ctgatttcct tcattatcag
    10801 ggattcttgc ttctgctaga ttgattgcga cacgttcgaa cgagactgct gaccgcccac
    10861 ctgcttgtcc gacacagatc acgacatctg gttggtgctg ttggatggct tctttgacta
    10921 cttgactgct tttttcgaat acggtcggta cttccacttt gatgatttca gcaccgctga
    10981 tttcatctgg catttttttt actgcttcat aggctggatt cactttgtcc ccaccaaatg
    11041 gatcaaaacc tgttactagt actttcatct gttgttcctc cgtccgattg atttaacata
    11101 tggttatctt ttatcatacc attttccttg aacagcgtaa ataaaggaaa caatagttta
    11161 aataacataa cagatcaaac ttaatatatt cttataaaaa aatagtgttc cactacaatg
    11221 ttagaagagg ttgcgacaat tattctgtca caacccctct cttctattat ttaaatagaa
    11281 tcatataagc aatttggaaa actagcataa ataacgcaat aaacaactgg tttttgatca
    11341 ctccgtattt gtctttcatc tccagcatcg ctacaggcac gatattgaag ttagcagcca
    11401 tcggtgtcag cagggtccca caaaaaccgc aagtcaatgc aaccattcct attaacgctg
    11461 gattcgctcc atgactaaat acgaatggtg caccgatccc aaccgtcatc acggtgatgg
    11521 ccgcaaatgc attccccatg attaccgtaa atatcaccat gccaagagcg taaatgatga
    11581 tgccgatgtt cacatttcct tctggaacga tcgtacctac tgcattggaa atcactgtcc
    11641 caactccagc gcttgtaaat accgcaccta gagaagctaa aagcattggc aacatgctta
    11701 acggccctac tgtgcccagc atatctgctg catcatctaa aaatgtactt ggtcgattat
    11761 ctcgagaaaa gaacatcaag attagcatgg ctgcaaaaac accgacgccc acgccgacta
    11821 aagcacctaa attggtaaat agagcaaaca agatcgcaaa gacaccgata ctcaaagctg
    11881 gaataaaaat tttcattcct agtttgtctg acattttttc catatattct tttgatggaa
    11941 gccggctttc tcctttgctg actttcttag caattgctgg tatggtcatc gcaaagatca
    12001 agccaccgtt cacgattgcc ggaagccatc ttcctcctgc aataactacc cctaagaccg
    12061 tccagaaaaa ggctgaccca taacgatgag gattggtttt atctgttaaa tttcttactc
    12121 cagtgtaaat caatacgagt cccatcacga tataaaggat ctccagtaat ttatcgccta
    12181 ataaaatatc aggatttgta aaaaagtcca tcttattgcc cctttcctgg ataatatttc
    12241 ttcgctaatt tcttttcttt aagatagaag tagacacttg ccacaactaa agccgtgata
    12301 gccactggaa cttccactaa agcaagctgt cccaatgtta cgtcatatcc tagatctttc
    12361 agtgttgatt ggactagcaa cgcccctgct cctccgatga atagtacttg gccaaagaac
    12421 cagcagacat tttccatagc tgaagccata ccttttagtt cttcttcatg cttaggatgg
    12481 acttctaacc cttttgattc gatggtcccc aatgccatcg gtaaaatgat tggacgaaca
    12541 aatccagcaa ctccaccaaa actcacgtta aaagccgcaa agatcattcg aaagatccca
    12601 taaatatcta caatcatacc agcagatact ttcttgaatc gcttgatcaa ggaagccgct
    12661 gattctttca gaccatttct ttcaagcgtt cctgttgcca acataatgat gataaaaatc
    12721 gccatcccgc gattgtttac aaaacttgta cctaaaagtt ctaacattcc ttgaatgcca
    12781 agaccgccag tcaaagctgt aacaactaaa gcaaccatta cgatcaatat cgagtctaat
    12841 ttaaatgcaa acccgagaat aacaatcaag acgcctaaaa ggctaagata attttccata
    12901 tattttcctc cataaaatga caatattttt ttaattataa agcaaaacac ataaaaaata
    12961 tagttgtttt ctcacgaaat agacactatt tttaaatatt tttcgttatt ttttta
//
LOCUS       DAKCAA010000069        12986 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000069 DAKCAA010000000
VERSION     DAKCAA010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.070"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(77..149)
                     /locus_tag="OUE31_002232"
     tRNA            complement(77..149)
                     /locus_tag="OUE31_002232"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="OUE31_002233"
     CDS             530..1099
                     /locus_tag="OUE31_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HCU0223214.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="OUE31_002234"
     CDS             1086..1946
                     /locus_tag="OUE31_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCU0223215.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="OUE31_002235"
     CDS             2136..2840
                     /locus_tag="OUE31_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0223216.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="OUE31_002236"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="OUE31_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HCU0223217.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="OUE31_002237"
     CDS             4677..5993
                     /locus_tag="OUE31_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223218.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="OUE31_002238"
     CDS             5994..6863
                     /locus_tag="OUE31_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HCU0223219.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="OUE31_002239"
     CDS             6918..7727
                     /locus_tag="OUE31_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCU0223220.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="OUE31_002240"
     CDS             complement(7830..8459)
                     /locus_tag="OUE31_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HCU0223221.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="OUE31_002241"
     CDS             8629..9921
                     /locus_tag="OUE31_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCU0223222.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="OUE31_002242"
     CDS             complement(9997..10659)
                     /locus_tag="OUE31_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCU0223223.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="OUE31_002243"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="OUE31_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HCU0223224.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="OUE31_002244"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="OUE31_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HCU0223225.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4325 a         2243 c         2807 g         3611 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttc
//
LOCUS       DAKCAA010000070        12939 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000070 DAKCAA010000000
VERSION     DAKCAA010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.071"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            4..939
                     /locus_tag="OUE31_002245"
     CDS             4..939
                     /locus_tag="OUE31_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HCU0223226.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            1072..1851
                     /locus_tag="OUE31_002246"
     CDS             1072..1851
                     /locus_tag="OUE31_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCU0223227.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            1844..2161
                     /locus_tag="OUE31_002247"
     CDS             1844..2161
                     /locus_tag="OUE31_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCU0223228.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            2405..4015
                     /locus_tag="OUE31_002248"
     CDS             2405..4015
                     /locus_tag="OUE31_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCU0223229.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            4172..5020
                     /locus_tag="OUE31_002249"
     CDS             4172..5020
                     /locus_tag="OUE31_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCU0223230.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            5251..5730
                     /locus_tag="OUE31_002250"
     CDS             5251..5730
                     /locus_tag="OUE31_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223231.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            5763..7991
                     /locus_tag="OUE31_002251"
     CDS             5763..7991
                     /locus_tag="OUE31_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCU0223232.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            8120..9763
                     /locus_tag="OUE31_002252"
     CDS             8120..9763
                     /locus_tag="OUE31_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCU0223233.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(9836..10381)
                     /locus_tag="OUE31_002253"
     CDS             complement(9836..10381)
                     /locus_tag="OUE31_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HCU0223234.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(10404..10889)
                     /locus_tag="OUE31_002254"
     CDS             complement(10404..10889)
                     /locus_tag="OUE31_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCU0223235.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(10879..11691)
                     /locus_tag="OUE31_002255"
     CDS             complement(10879..11691)
                     /locus_tag="OUE31_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HCU0223236.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(11830..>12939)
                     /locus_tag="OUE31_002256"
     CDS             complement(11830..>12939)
                     /locus_tag="OUE31_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HCU0223237.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         4167 a         2378 c         2610 g         3784 t
ORIGIN      
        1 aacatggaaa attttaaaaa aagcggaatg ttttccgtaa ttgctgctct aggggctaat
       61 attctagttg ctatcagcaa atttgtcggc tatgcaatca gtggcagtgc cgccatgcta
      121 aacgaaagca tccacagtat cgttgattgc agcaatcaga ttttgctgtt attcggtgat
      181 aaacaagcca ataaaggaca gagcgagttg catcaatttg gtgaaggacg agcaaaatac
      241 tttttcagta caatcgtcgc aatgatgctt ttcttcggcg gtggggcact tggggtgatg
      301 gaagcttttg aaaagttgac gcatccatcc catgaagtgg gtaatccgat cattgttata
      361 gcaatactgt tatttggttt ggtaatcgaa ggaagttcgt tacgcgtggc aatgaaagaa
      421 atcaaagaat tgaatactga aaaactttcc acgatgcgct ttttgcgcga aagtcgacac
      481 agtgaaatac tgattatttt tacggaagac ttgtgtgctg taatcggttt ggtcttggct
      541 ttagcaggaa caatattgac ttatgcaacc gggattgctg catttgatgc gatcagcgga
      601 ttgctgatcg gtttcttgct gatgggagcc gccattttcc tagcaaaaga attttatagt
      661 ctgatcatcg gtgaaagcgt gacagcaagc gatttatcaa aaatcaagtt agcttttgaa
      721 cgtcctgaga tcagtcggct gatcgatata aaaacagttc atttaagtcc aacggagatt
      781 ttagttgcag caaaagcaga tatcgttggt aacaaagaga atgaagctta ctcggtcatc
      841 aatgatattg aaaaaaatat gcgtcagtct cttcctgaca agaagatgta tatatacatt
      901 gaaacagata aatatgaccc aaattattct cgtaaataaa acgtttattc atgaattgaa
      961 gcaaaaatga gaaaaatata atcttgtttt taaataaaac ggctacaatt tagcgaattt
     1021 atgttacaat gagtccgctg tttatttgtt gtaattaaag gagatatttt aatgaacaaa
     1081 aagaaaagtg cgccatggct tcaagctttg catgcagtga tgccactttg tataagctat
     1141 ataccagtag gattagcttg cggagtattg ttgcaaaaag ttggatttga tcctctctta
     1201 tcaggactgt tatcgattct ggtcttttcc ggtggcgcgc agtttttagt tgcatctatg
     1261 cttacgacgc aagcatcatt tgcaacgaca ttattgatgg ttttcttttt agaattacgc
     1321 tatacattat taggagcaag tcttgccggt tttatgaaaa aagaaaagcg gacgtttttg
     1381 gctgtctttt ctcaatcact gaatgatgaa aactatgcgg tgaactactt aaagttttca
     1441 actgaccctt cctggaataa aagaaaggct ttatatgtca attggttctc aatgactgca
     1501 tgggccggta gcaatatgat cggtaatttt ttcggctcgg tgattcgagt agatgctgac
     1561 cttgtccatt ttgctttgac ggccatgttc attttcatgt ttatcatgca gatgaaaagc
     1621 gcactactga tctttacagg tttattctca ggcgtattag gggtcgtatt catggtatta
     1681 ttccaaaata ctttcggatt gattgcagca acagtcattg cttcatttgc cggatttatg
     1741 ctggagaagg cattcaaaaa agaaaaagct aagaaactaa gagaccgcgg taaagatgtc
     1801 aatgagccgc tcttcaactt cccggaacag gaggccaatc accatgacta aactatattt
     1861 gctactttta gttgcttgtc tgttcatcgt ggcatatatc ccgcgcttgt tcccgatgct
     1921 ttattttact catcgaaaag tgccatcctg gttcagtgac tggatgaaat atgtaccggt
     1981 ggcattattt gcggcgttag cttttaaaga tgttttcatt actcatgaac atctggatat
     2041 tgcttggaat atcaaaatag ctgcaatgat tctagtagca ggcgtggctt acaaaacacg
     2101 ttcgatggcg ttgtcagttt tgacaggact tgcgtctgtc tttttgctgt ctatgcttta
     2161 aactgtttta ttttattaaa aacagagatt gcgacataag ttgttcaaac tgatctatcc
     2221 gaactgcatt tgcaacagtc aattctggat gcaagtttat tcgtagggat aaaaaagatt
     2281 agtgttggct tatgatgcaa gctctttttt attttaggaa ttagagaggg atttgtcctt
     2341 ctatgatttt ttgctataat agggaagatg tttattttat gaaagaatag ttgagggaat
     2401 ttaaatgaat aaaaaattga tgcaaggaac attttggcta acctttgcta atcttctatg
     2461 taaagtttta ggggtagtct atttgattcc ctggctaagt atgatgggga acaatcaaga
     2521 tggtatgctt gctacgacat tgtataatgt tggctatctt ccttatggat tgttcctgat
     2581 gcttggtaca gtcggatttc caaatgcgat tgcaaaaaaa gtagctgtag ccacaaaaga
     2641 aggagataac gctgcttgtc ggctgatttt tagaagtacg atcaatatca tgtttgtcat
     2701 cggtatcgcc tctgctgcac tgatgtattt atttgctcct ttactagccg gaatcagtcc
     2761 gattgctaac gttaataatg ggatactagc tatcagaagt ttatgcccat ctttgattgc
     2821 tatcccaatt cttagtgcaa tgagaggata tttccaagga aaaaatgatc tgcggcctta
     2881 tggaacttct ttgattatcg aacaggctgt gcgagtgatc gttatcttgg ctggtactta
     2941 ttacttgcgc gtattgactg acggaaccat attagaagct gtattgatca gtacagtcgc
     3001 ttctttcttc ggtgggttag ctgcgattat ccatatgtat atcgtcggac gcagaaaaga
     3061 cttcttcgaa cttaaagatt ttttgatttc cagccgttat ttcgaaagag aaaaccgatc
     3121 tgcctctgtc tctatcattc gggaaacact accgtttatt tttgtcggct cagtcattac
     3181 tatcgttcaa atgatcgacc aagtaacgat gaaaccactg cttcactttt tccgtccaga
     3241 gatcgcagat cagcaactgg aattcttatt cagccgtgct tctgtcaatc caaataaatt
     3301 gacattgatc ctgatctcca tggtaggaac agtagctata agcagcttgc caatattaag
     3361 cacgatgaag aaaaaagatc ggatacaaat cgaaaaaaca gtaggagata gtttttcgat
     3421 tgcgttattg attcttcttc cttcattgac tggaatgtct ttattagctg gaccactata
     3481 cacattgttt tttggctatg atcctgaaag tgtcggatat ttccaaatgg ctttgctagc
     3541 ttctttgttt ttctctttat tcacgatcct atctacgatg cttcaatctt tgaatcacca
     3601 tcgttttgcg atccgattaa ctgtagaagc aattatcctg aaagtcatct tccaagtaat
     3661 cggattagga ttagttggcg gatacgggat gagcttatca aatggcttag cattcggtat
     3721 tgtctttgtt cgcggctatc actttatgtg caaagaatac cgaatagcac ctttagcaaa
     3781 gatcagcaat tttttcttaa aaactttccg ctccaccctg attatgcttg cagtatgttt
     3841 tgccgttttc tttttgctga atcagcgatt gtcaatggaa tcaaaaagct atgcaatgat
     3901 ttattgtgtg gctgtaggaa gtattggcgg cttagtattt ttattttctc aattcggaaa
     3961 aaatgggttt cgaatgttga aaaatgttaa acatcatagc agaagcaaag aataggttaa
     4021 ctaatcgttt tttgctgtca cttgaaaaac ggcaactcgt atgattacgc ttgtcgtttt
     4081 tctattttcc aattttagtt tcatatctaa tcttacttat gatatagtta taaggtctgg
     4141 aaaaattctt tgaaacgagg aaattaaaca catgaaactt gcagtagtta cagatagttc
     4201 ggcatatctg ccggaacgta tcaagaacca tcccgactta ttcgttattc caatcccttt
     4261 gattatggat gggaaaattt ataacgaagg aatcgatatc gaagcggatg aatattatgg
     4321 acttttaaaa aacagtaaag attttcctac tacttcacaa cctgtcgtag gggaagtttt
     4381 gggtttatat gaggaattga aagagaaagg gtatgacacg attttaagta tccatctttc
     4441 ttcagggatt tctggctttg tcaacacatt atttgcgatg aaagatgaca tcagcggagt
     4501 aacggtcatt ccttatgact ctaagatcac tagtatgccg atgggacaca tggtagaagc
     4561 tgccttagac ttaaatgatg aaggtcagtc ccttgatgaa atacttgcac atatcgatcg
     4621 aatccgagat aatacctacg cttatctgat tgtagatgat ttgaacaatt tagtacgagg
     4681 aggacgtttg acaaatggtg cagcgctgat tggcagctta ttaaaaatca aaccgatcct
     4741 gacattttct gaagggaaaa ttgttttatt cgaaaaaatc cgttcaagta aaaaagcatt
     4801 tgctcgagct gaagaaatta ttggtagaag aaataacgaa atacaaccgc cagtcaaact
     4861 ttacgtgata catgcaaata atttagaagt agcgattgcg gagaaagaga aattgcagaa
     4921 aaaatatcca aatgcagaaa tcgaaattgg tcatttcgga ccagtcattg gtacacattt
     4981 aggtgaaaaa gccatcggca ttgccatttc agcgcaataa ttccttttat tcaaaaaaca
     5041 taccaaaaat attccaacat catcttggac tttctacatg ttactaatga gcgtgtaaaa
     5101 gaacgagatg gtgtttttat ttctatcaat gaagctcttt ttctttgcaa tcctcacttc
     5161 aatcctctat aatgtcgcat atagtttagt aaatgagtaa actactaatt tacttattta
     5221 ctaaaaataa aaggatgagg agttaaaata atggaaatac caacaaattt aaaacataaa
     5281 ccagtaatcg ttgtagaaga ctatgataaa gttgatggaa gaaatgcatt aaatacggat
     5341 gcaaaagggc tttcactggg ccttgctcag tggaatgatc gtggaaaagt cgatatctca
     5401 ggcaaggtat ggcgacatac tggagaaaaa tggtcacgac agtcggaaga attaccaatc
     5461 acacgtattt tagatttagc gatcttagct gcacaaggaa gtttatactt ccaagatgct
     5521 tatcgttatg aaaaatttta tgatccagaa aatccagtcg tagacatcat tggattacaa
     5581 gggaaccgaa tgacggtaga agtagatacc aaaaatccaa agatcgatga agacatcatt
     5641 ttgtattacg atacactaca aaaagacgga gaactgattg gggaacgatt ccgtatttta
     5701 aaacgtcttt tagatgagct aggatattaa tagacagaga tgatcaaaag gggaagagaa
     5761 gcatggagaa tttctcacta acagaaaacc gaaccttttc acggctagaa aagcaaatga
     5821 tctggaagaa accgaaaagc catcggacaa gtgcagaaga atggcggatc gcctccgaaa
     5881 tcaaagggaa ttggcaagat cctgaaatga aaatcagtaa cgtacttttg gaaggagatg
     5941 ccgggtcggg gaagacacaa ttagccaaag cactatctgc tgatctgcaa cttccctata
     6001 caaaagtgac ctgttttgca gatatggaca aatcagatgt tttcggagcc ttattacctg
     6061 tagtagattc taataaggaa caagaccaag aattactaga agctatttac caaacagata
     6121 cacttgaagc tgtactgaca ctgatccaga accattacgg cattgatcct ttttctgcta
     6181 aagaaaaatt agcagagcta gttcaaagga tcgaagctga ttatccagat gcaatccatt
     6241 acagctatta cccttctgaa atcgttcgag cgattgaaaa aggatattta ttagagattc
     6301 aagagccgac tgtcatccga gatgcctctg ttcttgtggc acttaactca gcgctcgaac
     6361 caaatgggat gttgaattta ccgacaggaa tcattcgtcg ccatccagat tgcgtcattg
     6421 tgatcactac aaatcgaaat taccaaggaa atcgcccatt aaatgaatct ttaagagatc
     6481 ggatgcaaca tgcggaaaaa atggatcttc ctgccttaga agtcatggca gaacgtgcga
     6541 tggcgaaaac tatgatccaa aaacaagaac ttctcttaaa gatggcagag attatccgtt
     6601 tgttggatga aactgcaaaa gctaacgcca tcaaaggtgt agcaggaatg cgttcttatt
     6661 tttattgggc aaatacctat aagcaaggac aagatttact ccagtcgatt tatccaaaag
     6721 ttttgtataa attatccact gattcagatg aattggcaat tcttgaacaa gctttgtctg
     6781 acagtggatt gctactggaa cttcaggaca tattgagaaa agaaaaatgg ggtcatcctc
     6841 aatctgagca tacaaaagga agaaccatta gcgccgaaga agcaaatgaa cgaaacatca
     6901 ctgaaaatgc tgaagaaatt ctgcgcttag atgaaaagaa atcgttgtct gctgaagaac
     6961 caaatgaggg agaagagaaa caagaagaaa caatagaaaa aaacgagatt cctcctcaaa
     7021 tgcaaaaaga acgcagtagc gatatcgaag gaaaaaatca aaaagaacaa caaacaggag
     7081 atgattctca agaaatgtct gcttctgaca tggaagcaca tgataaggaa atcaagaagc
     7141 aactgaataa agaagcgcga caaatcatga aggaaacgat tcatgaaaaa gaaggtctca
     7201 tcgttcaccg accagctttc caaggaaaaa cgccggaagc acgtgagcta cacatgcaag
     7261 taatgccaat agtagaatca cttagccggc aaattttaga gttactggat aatgaacaaa
     7321 cagagacgta ccaaaaagga aaatacgaag gtcagcggtt caatgcaagc aaagtagcat
     7381 atggtgattt gagaaatttt gacaaaaaga acccgccaca tgagcaacct tctttagcgg
     7441 tagctgtacg gatcgatgaa tctgggtcaa tgatacggga tgatcggatc gaagcggcaa
     7501 aaaaagcagc gattgccatt gccgaatttt ctaagaaagt cgatatccca ttgttgattt
     7561 acggagatac agcagaccgt tcgtcaagag aaaagacttc tttgttttct tataaagaat
     7621 ttgaagacgg atttcaatgg ttaaatgaaa aattagtcac tatgaaacca aggcaaaaca
     7681 atcgtgatgg tgctgcactt cgtttagcag cagaaaaatt aaacagacaa tccgcaacaa
     7741 ccaaactgtt gcttaatatt agtgacggtc agccaaaagc gttgccggat tatacaggca
     7801 aaaaagcaaa agaagatatc cagtctgttt tgaaagaata tgaacgtcaa ggaatcctat
     7861 ttgtctccgc agctattggc caagacaaag aagaaatcaa gtcgatctac ggtgaaagtc
     7921 gttttgtaga tattactgac ttgaatgaat ttcccaagca aatgattcaa ctgattgccc
     7981 gctatctatg ataaaataaa gctcaacgaa cgcacttagc agattcgttg agcttttcgt
     8041 ttctagttac cggtaacaag gatacttcta aaatagaatc ggttataatc aagagggacc
     8101 gttaaaggag tgaaacgata tgatacaaga acaaaaatgg tggaaagaag cagtaggcta
     8161 tcaaatctat cctgctagtt tcaaagatag caatggcgat ggtcaaggag acatcaatgg
     8221 gatccgtgaa aaacttaatt atttgaaaga tcttggtatc ggctttatct ggatcaatcc
     8281 gatctatcaa tctccatttg tcgataatgg ttatgacgta agtgactatc aagatataga
     8341 agagagattc ggaacgatgg aagattttga tttattgcta aaagaagcac atgaattagg
     8401 gatcaaagtg attatggatc ttgtcatcaa ccatagttcg gatcagcatc aatggtttga
     8461 agaatcgaaa aaatctaaag aaagcccgta tcgcgattat tacatttggg tcgacggggt
     8521 agatggcaaa gaaccgaata attggacatc gattttcggc ggttctgctt gggagtattc
     8581 tcatgaaact ggacagtatt atctgcatgt ttttgcaaaa gaacaaccag acttaaattg
     8641 ggaaagcgag aaattgaaag aagaactatt caatatgatc cgatggtggt tggataaagg
     8701 gatagatgga tttcgtttag atgcgatttc tcatgtaaaa aaagatgaat attcagtaaa
     8761 agccacagag aaccctttct caccctttca aaatgtctca ggaatcgaag aacatttgac
     8821 cgatttgaaa catgtttttg aagagtacga tatcatgact gtcggagaag caagtggtgt
     8881 cactgcagaa gaaggaccac aatgggtagg gaaagacggt tatttcgata tgatattcga
     8941 atttgatcat atccatatct ggcagcaaga aaaagaaggg caattagatg tccttaaatt
     9001 gaaacttgca ttaagcgctt ggcaaacttc attggatggt atcggatgga acgctttata
     9061 tatggaaaac catgatgttc ctcgtgccgt ttcagtgttt ggagatactc gtcccgattt
     9121 ttgggctatg tctgcaaaag caatcgctat gatgtatttc tttttgcaag gtacgccatt
     9181 tatttatcaa ggacaggaaa tcggaatgac gaatatgccc tttgaatcga tcgatcaagt
     9241 tgatgcagta gattcgaaaa gactttataa aaggctgctt gcggaaggta agacaagaga
     9301 agaagcattg gatatcattc gtgaaacaac gagagacaac agcaggacac ccatgcaatg
     9361 gacttcggaa caatatgctg gtttttctac acatgaacct tggctgatca ctaatccaaa
     9421 taccaaaacg atcaatgtag aacaacaaga atatgaacca gagtcggtcc tgcaattcta
     9481 taagaacatg atccgcatta gacaaaccaa taaaggtctg atatacggtt cttataaaga
     9541 atatcttcat gaacatccac aactttatgt ctatgaaaga tatttagaag atgaacaata
     9601 tcttattatg gtaaacttaa cagaatcact tgctgactat gaacttccaa aagaagcaga
     9661 tcagtcctgg acattactct tgtcaaattc ctctagcgga gaatttgaag ctaaaggcat
     9721 actagcacct tatgaagctc ggttatataa aacaaacaag taaaacttcc tcgttaaagt
     9781 tcattagttg gactttgcga ggaagttttt cagattgctc tgtcaattac tcatttcaat
     9841 aattcgctct aggaccaccg atatatttag gacgagagcg aagggctgtc acgtgagctt
     9901 gtccaagggt tttcaaacga ggtctgacag gtacttggac atgtttgata tgcataccga
     9961 ttgatgtgtc accgatatcg ataccggctt gtccaactac gtgttccact tcgacaggat
    10021 cattgaactg gtcaaaagca gcaacagaac aagcacctcc agcatgtagt gcaggaacaa
    10081 cagagacaat ttcgaaattt tttgcttctg ccactgttcg ttctactact aatgctcggt
    10141 tcaaatgttc acaaccttgg acagctagcg caatttcttt aggatccaac aactctttta
    10201 acgtacggat gatccattga ccaacttccg cactggaatt ttttccaata tgtcctccaa
    10261 cgacttcgct tgtgctgcat cctaaaacaa aaagatcacc ttttttcaag tgtgcctcag
    10321 ccaatatgtc attaactatt tcagtcaatt ggtcttttaa ttctttttct gacaacttca
    10381 ttttctaaaa ccttcttttt caattaatat tgcttccgtg cttgaatacg ttgaagactt
    10441 gcagttatag gaaaggcaag tcccattcca atcagatttt ggaagatgtt tcctggtata
    10501 gaagccactc cagccggcca atcatataaa atccaaccgg cgataccata gccgatgatc
    10561 ataactaagc ttcctaataa aagccctaat ccccacatac gagtagaaga tttgctgaaa
    10621 gaaccagcaa catatccttg taacccgtgg atcactaatg aaaaaactgc ccactgcgga
    10681 tatcctgaaa tcaaatcgat caatagacca ctggaagcac caacaactaa tccacccgtt
    10741 ggaccataaa gaaaagcagc ggtatagatc ccggcctcgc ataatgtcac aaatccattc
    10801 gtagccggta cagggatcaa aattgttaat gaaagggcaa ctgtcaacgc aatcagcata
    10861 gcatagatcg ttaattgctt agttttcatt tctcattcct cctttttgaa taccgccaga
    10921 ccagacactt ccggtatgat cgttcatcag cacgccatta gaaatacaat gggcaacaaa
    10981 ttttttactt tctgctactg ctttggtaaa atctgcccct aacacaagat tcgctgttat
    11041 tgcagaagaa aaggcacaac cggccccgtt tactgttgta gtgtcgattt ttttatgaga
    11101 aaatacctca taatgatcaa ttgaatagag aagatccaca gcttcatctc cagccatcct
    11161 tgtgccgcct ttgatcacaa tgttttttgt tcctgaagca gtgagttctt tagcgagatg
    11221 gatcatttct gttaacgaag agggaagagc ttgaccagaa agtaaagcag cttctgccaa
    11281 attaggcgta atcatcgtaa caagtggaaa aagttcttcg atgagctgcg aaatatacaa
    11341 ttgattgatc acagcttcag tttctttgaa tgccaaaaca gggtctaaaa tgattgggat
    11401 attttgtttt gtttttatga agtctcgaac aaccatgatt gcttcacttg aattcaataa
    11461 cccaattttg ataccatcta atgaagtcat tttatcaatc gaaactaact gtcgtttaag
    11521 caattccaaa gatatagatt ccagcataaa tcgctcatta atatctagtg cccctataga
    11581 agtcaaggcg cttagtccga atagaccaaa attctcaaaa gtttttaaat ctgtttggat
    11641 tcctccacca gcaaatggat cagaaccgcc aattgtcaag attcttttca taacattttc
    11701 ctccatgaat aagagtataa cgaaattttc aaaaaagaaa aacagccaat tggcatattt
    11761 ttatctcatc caatttaaaa aaacaaaaag aaaagaaaga ccaaaatgga tctttctttc
    11821 cttaaatagt taggactttt gtgattttaa ttctttctcg atttgaagcc gttgcacttt
    11881 cattgtagct gttcgcggga ttgcatcaaa atcacggatg atagggacgt tcaagcgagg
    11941 aagttcatgg acttgctccc accatcgatt ccaatccatt tctttatcag gagctaaagc
    12001 aataatcggt tgtggagaat gatttttatc ccttacaatc actacttctg ccaaaaaatc
    12061 taacgaatct aataaaaagt cttcaatagc taatgtacta ttgatcgttt cgatcaaatc
    12121 cacttgccga tctttcaaaa ataggtggcc atgcttatcc ataaaaccgt aatctccgct
    12181 atcccaccaa tcgccataaa cattttcctg gaaccgtgca tcttccttgt aataagtcaa
    12241 agcccgtcct ttagacagta attgtatatg accatctgtg ttttcaggta ggacattccc
    12301 aactgaatct gtaatccgag cgcttgtcat gtcttccagt ccaacgccca tatctcttgc
    12361 atcacttgtt ttcaaactct ctagtgtatg agccttaaga atcattggtc cgcattcact
    12421 ttggccatat acttgaagaa ataccgcatc ctgtgccatc gacgttcgca aaaatgtctt
    12481 cattgtctgg ttgtttatag catcaaaagt ggagtgatag tatcggatac ccgaaaaagc
    12541 ttctggatgc tccttagcag taaaacgcca ctgaacaaag ttattcggat gggtctctag
    12601 tgcaattggc cggtgagctt ccaacatatg aacaactttt gaactttgtg cgtttgctaa
    12661 aggcatcata ggaaatccca tggacatcaa agaagagata ccaatattga atctggaatg
    12721 cactggagag atgtgaaaag cgattaattt cttttccgaa atttttgtga aaactgtttt
    12781 ttgccatttc gtccgccatc ccatagaatg agcagaatga caaataagtt tagggatacc
    12841 agttgtacca gaagtatggg tcatataaga aatttcattt ttgtctaaaa atgattgaga
    12901 aacagacaaa gcaggttgtt ccattaaata aagaatagg
//
LOCUS       DAKCAA010000071        12819 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000071 DAKCAA010000000
VERSION     DAKCAA010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.072"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            314..673
                     /locus_tag="OUE31_002257"
                     /pseudo
     CDS             314..673
                     /locus_tag="OUE31_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(968..2101)
                     /locus_tag="OUE31_002258"
     CDS             complement(968..2101)
                     /locus_tag="OUE31_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCU0223238.1"
                     /translation="MLLNFKMTLTMLAFSLLVTGVILVSFFFLRNNLEGISIASTLGE
                     DVYFMEEGKTVQAETQMEASKSSNNQFMTISMIDKAYQDELFKYLPAMVLVICSAVML
                     LTFILWLVLRKIYSNQILAITRDLTFIDQVPKNTVKDEALNAAFNKLKDKFDGHLEDY
                     RRLNSYLTHEQKNAIAILRTNLEIERQHADQGNLMLLDRMTDSIDDILTLSNNSEDLS
                     TEVVDVSLICAEVCDAYKMNYPNLLFAFTEDQPTLIHGRDRWIYRAVSNLVDNAIKYG
                     EGKLVIVTISNQKGSVIIEVKDQGIGIPQEKQASIFSHQYRVHGLKQDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            complement(2092..2760)
                     /locus_tag="OUE31_002259"
     CDS             complement(2092..2760)
                     /locus_tag="OUE31_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0223239.1"
                     /translation="MRVLVVEDNRELVLSVKKGLEQENISVDVAYDGESGEEKAFINS
                     YDGILLDLNLPKKDGLSVLQSLRAEEVESPVIIITARDEIEERAKGLDFGADDYLVKP
                     FELLELKARIRAVIRRYHGRALPQISIGALKIDPLGRRVSYQKTEVVLKPKEFDILLC
                     IAQRHPAVVSSEEISEHVYDEDFDPFSSVLRVHLARLKKKLAEAAEKEVLKTIRAKGY
                     QLCY"
     gene            complement(3216..4202)
                     /gene="lacD"
                     /locus_tag="OUE31_002260"
     CDS             complement(3216..4202)
                     /gene="lacD"
                     /locus_tag="OUE31_002260"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCU0223240.1"
                     /translation="MNEEKRQYIKQLCNEDGVIGALAIDQRGALKKMITKFKGSEAEE
                     SEIVEFKEIVSSQLTKYASSILLDPEYGLPAADVRAKNAGLLLAYEKTGYDASTPGRL
                     PDLLSIWSVKRLKEAGADACKFLLYYDVDEAEEINNQKHAFIERIGSECQAENLPFFL
                     ELVSYDANISDATSKEYAIKKPHKVNDMMKEFSDPRYGVDVLKVEVPVNMNYVEGYGT
                     DEVVYTKAQAANFFKEQAEATNLPFIFLSAGVKAELFQETLRFAKNAGSTFNGVLCGR
                     ATWADGVESYIVDGKEAAMEWMNTQGRKNIEELNAVLKETATPVEVLTSSLS"
     gene            complement(4215..5141)
                     /gene="lacC"
                     /locus_tag="OUE31_002261"
     CDS             complement(4215..5141)
                     /gene="lacC"
                     /locus_tag="OUE31_002261"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HCU0223241.1"
                     /translation="MILTITMNPSIDISYPLETFKLDTVNRVRNVRKTAGGKGLNVTR
                     ILKQLDTEVIASGLIGGFLGEEIKKDLTQNEIAHDFLPISGETRNCIAVLHDGKQTEI
                     LENGPVITEQEARAFLQHFEKLAVKAEIISFSGSLPEGLPADFYRQMLQVCQPKPVVL
                     DCSGTALREVLRGSVKPKLIKPNTEELAGLLGREISTELSDLKAALSDSMFDEIEWIV
                     VSMGGDGAFAKHHETFYCVTIPKIDVVNPVGSGDATVAGLTAAIQQGLSDEAVLKQGN
                     VLGMLNAQEATTGYVQLANYQKLYDQILVEKV"
     gene            complement(5154..5669)
                     /gene="lacB"
                     /locus_tag="OUE31_002262"
     CDS             complement(5154..5669)
                     /gene="lacB"
                     /locus_tag="OUE31_002262"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HCU0223242.1"
                     /translation="MKIAIGCDHIVTDTKMAVSDFLKSKGHEVLDMGTYDFTRTHYPI
                     YGKKVGEAVTSGEADLGVCLCGTGVGINNAVNKVPGIRSALVRDMTTAIYAKEQLNAN
                     VIGFGARITGEFLICDILEAFINADYQETEENKKLIAKIDHVEKASDKQSDPHFFDEF
                     IEKWDRGEYHD"
     gene            complement(5688..6116)
                     /gene="lacA"
                     /locus_tag="OUE31_002263"
     CDS             complement(5688..6116)
                     /gene="lacA"
                     /locus_tag="OUE31_002263"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HCU0223243.1"
                     /translation="MRVVIGSDSDGMELKELIKKKLIKEGITVVDKSETASEDFVEST
                     LAIANDLNENEGSLGIAVDGYGAGSFITATKVKGMVAAEVSDERSAYMTRKHNNSRMI
                     TLGSKIVGDELALNIVKEFLQANYDGGRHQVRVDMLNKMA"
     gene            complement(6136..6909)
                     /locus_tag="OUE31_002264"
     CDS             complement(6136..6909)
                     /locus_tag="OUE31_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCU0223244.1"
                     /translation="MLKTERQRSILAMCDRYGTITVKFIQEVLNVSDMTIRRDLEELA
                     QKKKLLRVHGGAQKIDYLEMSTSIEANELSHTEKKKLHTKEKEYIAKNAAAHINQEDD
                     TIFLGSGTTIELMTRYIKPSSLRIVTNSLPVFNLLSEIKRFELYLIGGLYREKTGAFV
                     GSIANEAVQKIGIKKAFVGVNGLKGSEVSNFSIEEGTLQKIVLDNAAEKCLVSDANKF
                     DHSDFYNFYDLRKIDKLFTDSTLSAELKSYYQQFTKIIQ"
     gene            7074..7553
                     /locus_tag="OUE31_002265"
     CDS             7074..7553
                     /locus_tag="OUE31_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0223245.1"
                     /translation="MNEFFFKDTVYVSDKQSQEEVFEEVYQDLLKKELVTEDFLENLL
                     ERERNYPTGLDLSPVSKILPDIAIPHTESEFVRTTRIIPIKVKNEIPFYNMISPSDQI
                     SASFLFMILNENGEAQAGMLANIMDFINSVDEEKLFSFFKLEDTEAIYHFLEEHFYI"
     gene            7610..7912
                     /locus_tag="OUE31_002266"
     CDS             7610..7912
                     /locus_tag="OUE31_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HCU0223246.1"
                     /translation="MIKILAACGAGVNSSHQIKSALETELKNRGYQVTCDAVMIKDIN
                     EEMLSHYDIFAQIANTDLGFDINIPVVDAGAILYRIPAMAEPVYQSMESAIQSLNK"
     gene            7934..9391
                     /locus_tag="OUE31_002267"
     CDS             7934..9391
                     /locus_tag="OUE31_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCU0223247.1"
                     /translation="MNTIIDIANKVFTPLINLGAAPLMTIVLTVIALFFKVKPSRALE
                     GGLKLGIALTGIGAIIGILTTAFSDAMTAFVERTGISLNITDVGWAPLATITWGSPYT
                     LYFLLIMVIVNIVMLAMKKTNTLDVDIFDIWHLAIVGLFAIFCGANLFIASALVIFIG
                     VLKIWNSDLMKPTFNDLLNAPDSNPMTTTHMNYMMNPIIMVFDKIFDKIFPWLDKYDF
                     DAAKLNSKIGFWGSKFAIGIYLGIFVGLLAGQTPTQIFSLAFTAAVCLELFSLIGAWF
                     IAAVEPLSQGITDFANKRLKGRTINIGLDWPFIAGRAEIWAAANVLAPIMLLEAIILP
                     GNKLLPLGGIIAMGVTPALLVVTRGKLIRMIVIGAIELPLFLWSGTLIAPFVTQTAKA
                     VGAFPAGLNGSAMISHTTMEGPIEKFLGYLVGNASQGQIEFVIYAALALGAYLLIFIW
                     YARQMKKRNAAYAAEKEENASPATAHNMTYAAEAK"
     gene            complement(9984..10736)
                     /locus_tag="OUE31_002268"
     CDS             complement(9984..10736)
                     /locus_tag="OUE31_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCU0223248.1"
                     /translation="MLKTDRFQAIMSLLEVNGTVRVSDIMEKFSVSDMTVRRDLDEME
                     KQGLLERVHGGAKLKDFYRHVELSHREKQIMLQEEKQRIVEKANEMINDGDTIFLGPG
                     TTIELMSKIIQGDSLRIVTNCLPVFEELNKRKGNRKIYLLGGEMRETTQCFVGEITNK
                     SLQDMNFHKAFFSCNALNEQKIMTSTFEEGQTQQIALNNSVERFLLIDHSKIGKRDFS
                     VYYNLNDVTVVITDDDEQKHYEKIEKEEKYVV"
     gene            complement(10951..11187)
                     /locus_tag="OUE31_002269"
                     /pseudo
     CDS             complement(10951..11187)
                     /locus_tag="OUE31_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178530.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
     gene            complement(11197..12155)
                     /locus_tag="OUE31_002270"
                     /pseudo
     CDS             complement(11197..12155)
                     /locus_tag="OUE31_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(12361..12549)
                     /locus_tag="OUE31_002271"
                     /pseudo
     CDS             complement(12361..12549)
                     /locus_tag="OUE31_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="phosphoenolpyruvate-dependent sugar
                     phosphotransferase system; catalyzes the phosphorylation
                     of incoming sugar substrates concomitant with their
                     translocation across the cell membrane; IIB is
                     phosphorylated by IIA and then transfers the phosphoryl
                     group to the sugar; IIC forms the translocation channel;
                     incomplete; partial in the middle of a contig; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
     gene            12626..>12819
                     /locus_tag="OUE31_002272"
     CDS             12626..>12819
                     /locus_tag="OUE31_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCU0223249.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKK"
BASE COUNT         3705 a         2718 c         2215 g         4181 t
ORIGIN      
        1 taaataactc ataaaaaata ttttgacttt caaaatcact tttgctacca gaagttgagg
       61 cgaagtgttt taagcatagt tgtaccctag tttgaccgtt aaaaataaat aacgatcgct
      121 agagtgcaac tatgtttgtt tgccctaccg tcagcgtcgg cttggcctct cacatccatt
      181 accgtcggga ttatctccgt tacataccct tacaaaatac gccctgtaag cattgcatga
      241 aaccaccgtg catttgcacc gtatttccgc cctagccgtt caaatcggtc gctaccacca
      301 ttcagaaaca cgtgcggtaa tggaaggttt ggaggaagct atccagacca ctaacgattg
      361 tccctatcgt cgtacgtttc actcagatca aggttggtcg tatcaaatga aagcttatag
      421 aaacaaattg aaggagtaca aaatctttca aagcatgtct cggaaaggga actgcttaga
      481 taattcactt atggagaatt tttttggctt attaaaacaa gagatttttc acgggaaagt
      541 ttataactgt ttcgaggaat taaaatcagc catcgatagc tatatctatt actacaataa
      601 tgaacggata aaacagaaat taaactggca aagtcccgtc caatttcgta aaacaaccgt
      661 tacggttgtg taaaaatatc attttagagc atgaaaaaaa gagtggattt ctccactcca
      721 aaaaagtcta acttttgggg gtcactacat ttttgatcct ttttatttga ttaattatat
      781 ccagctggat aataattttg ggggcaacat ttctatctta ctattatctt cctaaagtag
      841 tagactttct tattgggaaa aattacaaca aaaaggagtg gcttagttga caactccttt
      901 ttgtttacaa atcaattgga tatctataaa ttgtattttc taacgaattt tatagacatc
      961 tgatttgtca aattaagcta gacaatatgt ctttatctat gcagctcaaa aatacttcca
     1021 atggtgttcg ataatttaat gattttcttg gaatatggtt tcttttcgag gcaacggatt
     1081 gaataaaggt ttcatccgtg tccctaaagt ccattgtttt aggtaagcca tcctgcttga
     1141 gcccatgcac tcggtactga tgagaaaaaa ttgatgcctg tttctcctga ggaatgccaa
     1201 ttccctgatc ttttacttca ataatcacgc tacccttttg gtttgaaatg gtgacaatta
     1261 ccagttttcc ttcaccatat ttgattgcat tgtcaactaa attcgaaacc gcccgataaa
     1321 tccaacgatc tcgtccatga atcagggttg gttgatcttc agtaaacgca aacaaaagat
     1381 tcggataatt cattttgtag gcatcacaaa cttccgcaca gatcagtgaa acgtctacga
     1441 cttccgtgct aagatcctct gagttattgg ataatgtcaa aatatcgtca atactgtcgg
     1501 tcatccgatc taaaagcatt aaatttcctt gatcggcatg ttgccgttct atttccagat
     1561 tcgtacgcaa aatagcgatg gcatttttct gctcgtgggt cagataacta tttaatcgtc
     1621 gataatcctc caaatgacca tcgaacttat cctttagctt attaaaagcc gcatttaatg
     1681 cctcgtcctt cacagtattt ttaggaactt gatcaataaa cgttaaatca cgcgtaatcg
     1741 ctaagatttg attactgtaa attttgcgta aaaccaacca aagaataaac gttaataaca
     1801 tgacggcaga acaaataacc agcaccatcg ctggtaaata tttaaatagt tcgtcctggt
     1861 aagctttatc tatcatcgaa atagtcataa attgattgtt ggaagatttc gaagcttcca
     1921 tctgcgtctc tgcttgaacc gtcttaccct cttccataaa ataaacatct tcacctaagg
     1981 tagatgcgat actgattccc tccaaattat ttctcagaaa gaagaaactc actaaaatca
     2041 cgcctgtcac caacagtgaa aaagccagca tcgttaacgt cattttaaaa tttaatagca
     2101 tagctggtac ccctttgctc gaatggtttt taagacctct ttttcagctg cttcagccag
     2161 tttctttttt agacgagcca gatgcactcg cagaaccgac gaaaaaggat caaaatcttc
     2221 atcgtagaca tgttcagaaa tttcctcaga cgaaacaacc gctggatgac gctgagcgat
     2281 gcacagtaag atatcaaatt ccttgggttt caggaccacc tctgtctttt gatagctgac
     2341 ccttcgacct aatggatcaa tcttcaaagc accaattgaa atctgcggca gcgcacgtcc
     2401 atgataacga cgaataaccg cgcgtattcg tgcttttaat tctagtaact caaagggttt
     2461 gactaaataa tcatctgctc caaaatccaa gccttttgct cgttcttcaa tctcatcacg
     2521 tgcagtaata atgataactg gactttcgac ttcttcagca cggagacttt gtaaaacaga
     2581 taatccatct tttttaggca gatttaaatc tagtagtatc ccatcgtatg aattgatgaa
     2641 ggccttctct tctcctgact cgccatcata agctacatct acagaaatat tctcctgctc
     2701 taggcccttt tttacggata aaaccagctc acgattgtcc tcaaccacca gtacacgcat
     2761 gtatattcac tcctcatacg gatttagtaa ttacacttat gctttttagc atagtacacg
     2821 ctcttcttca aagtccacgt tctttttgtg aagatttgaa gaaattcata cattctgtta
     2881 aaaaacacat aattaagaat gattttactg tttgaaaata cctagaatag aaaaagactg
     2941 gaacctttcc tccagtctca ctactttcta tttgcttggt tttcttgtat atacttttca
     3001 aagttcgttg gtttatgacc aataagcctc gttagaatac tgaaaattgc catcaagtca
     3061 ttaagtacca catgtaagaa aatctctcta aagaaaaacc ccttcgtttt aactcactta
     3121 ctattttaga attcgttccc ctaataatgc agcatgattt tacgctttat gtataaaaaa
     3181 agactgcaag caattttgct tcacagtctg atttcttatg atagtgagct tgttaacact
     3241 tccaccggtg tagcagtttc tttcaatacg gcatttaatt cttcaatatt tttacgccct
     3301 tgcgtattca tccactccat cgctgcttct tttccatcaa cgatatagct ttctacacca
     3361 tctgcccaag tcgcacggcc gcaaagtaca ccattgaagg ttgagccggc atttttcgcg
     3421 aagcgcagtg tttcttggaa caactctgct tttacaccgg cgcttaggaa aataaatggc
     3481 aggttagtgg cttcagcctg ttccttgaag aagttagccg cttgtgcctt tgtgtacacg
     3541 acttcgtctg tcccatagcc ttccacataa ttcatattga cgggtacttc cacctttaac
     3601 acatctacgc cataacgtgg atcagaaaat tccttcatca tatcgttgac tttatgaggt
     3661 ttcttaatgg cgtattcttt cgaagtcgca tcagagatgt tcgcgtcata agaaacaagc
     3721 tccaagaaga agggtaagtt ttcagcctga cattctgagc cgattcgttc aataaaggca
     3781 tgtttttgat tattgatttc ttctgcttca tcgacatcat agtaaagtag gaacttacaa
     3841 gcatcggcgc ctgcttcttt taaacgttta actgaccaga tcgataataa atctggtaaa
     3901 cggccgggag ttgacgcatc gtaaccagtt ttttcataag ctaacagcaa gccggcattt
     3961 tttgctctaa cgtcagctgc tggcaagcca tattcgggat ctaataaaat cgatgaggca
     4021 tatttcgtta attgtgaaga aacaatttct ttaaattcaa cgatttctga ttcttctgct
     4081 tcgctgccct tgaattttgt gatcatcttc ttcaaagccc cgcgttgatc aattgctaag
     4141 gccccaatca ctccatcttc attgcatagt tgcttgatat attgacgttt ttcttcgttc
     4201 atttccgtat cctcctacac tttctccact aagatttgat catatagttt ttgataattg
     4261 gctaattgga catagccagt cgtcgcttcc tgagcattca gcattcctaa aacattaccc
     4321 tgttttaaca cggcttcatc cgaaagacct tgttgaatcg cagcggtcaa tccggcaacg
     4381 gtcgcatcac cagagccaac tggattgacg acatcaatct ttggaattgt cacgcaataa
     4441 aaagtctcgt gatgtttggc aaaggctccg tcgcccccca ttgaaaccac tatccattca
     4501 atttcatcaa acatcgaatc tgacaaggcg gcttttaaat ctgataattc tgttgagatt
     4561 tctcgtccta gcagaccagc cagctcttcg gtattgggtt ttattagctt aggctttaca
     4621 ctgcctcgca acacttccct taatgctgta cctgaacaat ctaaaacgac aggctttggc
     4681 tgacaaactt gcagcatttg tcgataaaaa tcagcaggca atccttctgg caagcttcct
     4741 gaaaaagaaa tgatttcggc tttaacagct aatttttcga aatgttgcaa gaacgccctt
     4801 gcttcttgtt cagtaataac aggtccgttt tctaggattt ccgtctgttt tccgtcatgt
     4861 aaaacagcga tgcaattacg tgtctctccg ctgataggta aaaagtcatg agcaatctca
     4921 ttttgagtca ggtccttttt aatctcttca cctaaaaaac cgccgattaa accactagca
     4981 atcacctccg tatctaattg cttcaagata cgtgtcacat ttaggccctt accgccagct
     5041 gttttgcgaa catttcttac tcgattgact gtgtcgagct tgaaggtttc taatggataa
     5101 gaaatatcaa tcgatggatt catcgttatt gttaaaatca tttgtccacc cgcttaatcg
     5161 tggtattcgc cacgatccca tttctcgata aattcatcga agaaatgcgg atcagactgc
     5221 ttgtcactgg ctttttcgac gtgatcgatt ttggcgatca attttttgtt ttcttcagtt
     5281 tcttgataat cggcattgat gaaggcctct aatatgtcac agatcaaaaa ttctcccgta
     5341 atccgagcgc caaagccgat cacattggca tttagttgtt ccttcgcata gatagcagtc
     5401 gtcatatcgc gaaccagcgc actgcggata ccaggtactt tattgacagc gttgttaatc
     5461 ccaacacctg ttccacacaa acaaactcct agatctgctt ctccgctagt cacggcctct
     5521 ccgacttttt ttccgtagat cggataatgg gttctggtaa agtcataggt ccccatatcc
     5581 aacacttcat gtccttttga ttttaagaaa tctgatactg ccatttttgt atctgtgacg
     5641 atgtggtcac agccaattgc gattttcatt tcattcatcc ttcctaatta cgccatttta
     5701 tttaacatgt cgacacgtac ttgatgacga ccaccatcat aatttgcttg tagaaattcc
     5761 ttaacaatat tcaacgccaa ctcatcgcca acaatttttg atccaagtgt gatcatccga
     5821 gaattattat gtttacgggt catatacgca ctgcgctcat ccgaaacttc tgctgctacc
     5881 attcctttaa cctttgttgc cgtgataaag ctgccagcgc cgtagccatc aaccgcgatt
     5941 cctaaactac cttcgttttc attcagatca tttgcgatcg ccaaagttga ttccacaaaa
     6001 tcttctgaag ccgtttcact cttatctact actgtaatac cttctttgat caattttttc
     6061 ttgattaatt cctttaattc catgccgtca ctgtctgaac caattactac acgcattttt
     6121 gtttcctcct attttttact gaatgatttt agtgaattgc tgataataac tcttcagctc
     6181 ggctgaaaga gtagaatccg taaataattt gtcgatcttg cgcaaatcat agaaattata
     6241 aaaatcgcta tggtcgaatt tgtttgcatc tgaaaccaaa catttttctg ccgcattatc
     6301 taaaacaatt ttttgcaagg taccttcttc aatactgaaa ttcgaaacct ccgaaccctt
     6361 caatccattc actccgacaa aagccttctt aataccgatt ttttgaacag cttcattggc
     6421 aattgaaccg acaaaggctc cagtcttttc ccgatatagc ccaccgatca aatacagttc
     6481 aaatcttttt atttcactta atagattgaa aaccggcaga ctattggtaa cgattcggag
     6541 agatgacggc ttgatgtatc gtgtcattaa ttcgatcgtt gtacccgatc caagaaaaat
     6601 cgtgtcgtct tcttgattga tatgagctgc cgcattttta gcgatgtatt ccttctcttt
     6661 tgtatgcagc ttcttttttt cagtatgaga aagctcattt gcttctatag aagtcgacat
     6721 ttccagataa tcgatttttt gtgcaccgcc atgaacgcgt aaaagctttt tcttctgcgc
     6781 gagttcctct agatctcggc ggatcgtcat atctgaaaca ttcagtactt cctgaataaa
     6841 tttgactgtt atcgtcccat agcgatcaca catcgctaag atcgaacgct gtcgttctgt
     6901 tttcagcata ttctgtacct ccacgacctt ataataaaac atttacgaac atttttcaac
     6961 acatattgtt cgtttatttt cgtttatgcg ttgacaatga ttttgtaagc ggttatactc
     7021 aacttgtaaa catataaata aacataaacg aactaataaa ggagctgttt tgtgtgaatg
     7081 aattcttttt caaagacact gtctatgttt ctgacaagca gtcgcaggaa gaagtgttcg
     7141 aggaagtcta tcaagatctg ttaaagaaag aattggtaac cgaagatttt ttggagaacc
     7201 ttttagaacg ggagcgtaat tatccgacgg gattagatct ctcacctgtc tctaaaatat
     7261 tgccagatat cgctatccct cataccgaaa gtgagtttgt gcgaaccacc cgtatcattc
     7321 caatcaaagt aaaaaatgaa atccctttct acaacatgat ctcgccaagc gatcagattt
     7381 ccgcttcatt tcttttcatg atcttgaacg aaaatggtga agcacaggct ggcatgttgg
     7441 ctaatatcat ggatttcatt aattctgttg acgaagaaaa actgttttcg tttttcaaat
     7501 tagaggacac agaagcgatt tatcattttt tagaagaaca tttttatata tagaagtctc
     7561 tgcctaaccg caggataaaa aataaactta ttttaagggg agaattatta tgatcaaaat
     7621 tttagcagca tgtggagcag gcgttaattc aagccatcaa atcaaaagcg ctttggaaac
     7681 tgaattgaaa aatcgtggct atcaagtcac ctgtgacgcc gttatgatca aagatatcaa
     7741 tgaagaaatg ctgtctcatt atgacatttt cgcacaaatt gccaacaccg acttgggttt
     7801 tgacattaac atccctgtcg ttgatgcagg tgctattctt tatcgtattc ctgctatggc
     7861 tgagcctgtt taccaaagta tggaaagcgc aatccaatca ttaaacaaat aggactaaag
     7921 aaaggaaaag catatgaata caattattga tattgccaat aaagtattta cccccctaat
     7981 taatttaggt gcggcaccgt taatgaccat cgtattaact gttattgctt tattttttaa
     8041 agtaaaaccg tcacgcgctc ttgaaggcgg gctcaaatta gggatcgccc tgactgggat
     8101 cggagctatt attggaattt taactactgc tttttcagac gctatgacag cttttgttga
     8161 acgcacaggt atttcattaa acattacaga tgtcggttgg gccccactag caaccatcac
     8221 atgggggtcg ccatacacgc tttatttttt actaattatg gtgatcgtca atattgtcat
     8281 gttagcaatg aaaaaaacca acacattaga tgtggatatt ttcgatattt ggcatttagc
     8341 aattgttggt ttgttcgcga tcttctgcgg tgctaatctg tttattgctt ctgcattagt
     8401 tattttcatt ggtgtattaa aaatttggaa ctccgactta atgaaaccaa ccttcaatga
     8461 cttgttaaat gcgccagaca gcaacccgat gaccacgact catatgaact acatgatgaa
     8521 tccgattatt atggttttcg ataaaatttt cgacaaaatc ttcccttggt tggataaata
     8581 tgatttcgat gctgccaaat tgaatagtaa aattggcttc tggggatcaa aattcgcgat
     8641 tggaatttat ttggggattt ttgttggatt actagcagga caaacaccaa cgcaaatttt
     8701 ctcgctagcc tttaccgctg ccgtctgttt ggaattgttc tctttgatag gcgcttggtt
     8761 catcgcagcc gtagaaccgt tatcacaagg gattaccgat tttgccaata aacgactaaa
     8821 aggacgtacc atcaacatag gtttagactg gcctttcata gcaggccgcg ctgaaatctg
     8881 ggctgccgct aacgtattag caccaatcat gttgctagaa gccatcatct taccaggaaa
     8941 taaattattg ccactaggcg gaatcatcgc aatgggtgtt accccagcac tattggtcgt
     9001 aactcgtgga aaattaatcc gtatgatcgt aatcggcgcg atcgaattac cattattctt
     9061 atggtccggc accttgatcg ccccgttcgt tactcaaaca gctaaagcag tcggagcctt
     9121 tccagccggc ttgaacgggt ccgccatgat ctctcataca acgatggaag gcccgattga
     9181 aaaattccta ggttatttag tcggtaatgc ttctcaagga caaatcgaat ttgtgatata
     9241 cgctgcctta gcattaggtg catacctttt aatcttcatt tggtacgctc gtcaaatgaa
     9301 aaaacgcaac gctgcatacg cagctgaaaa agaagagaat gcatctccgg caacggcgca
     9361 taatatgact tatgcagccg aagctaaata agctaaaaac accccgaatg tctttagact
     9421 tcggggtatt attttaccta taaaaaataa atagatgtaa aatccatttc aaaaagcata
     9481 gcccatctct tgccacaccc aataaagaaa ttatcaacgt ttatgctttt tttaactcct
     9541 ttaagcttgc ctttgttggt attcctcaac gattcttttt gtgttcttgt ttgttttgtg
     9601 ctttttgact ttttgttgtt taattgcgaa ttccttgatt tcttttttcc tgaatcgctt
     9661 cgcatcccgc ggttatgcgt gcgatttcat cattgctttt tctgatctaa ctcgtttcat
     9721 gtcaaagagc ttcagctgac ttagtgtcca tggttgtttt gatatccctt ttcctcctta
     9781 ataaagcggt gattgatact gctatttttt ccttcacata aacataacat cccaaaaaaa
     9841 tcgactatct tttttcaaat ggtgtattca agtattcgga ggaattagta atgatgcacc
     9901 ctaaaaataa cataattcgc ttaaattcaa ggctaccaaa aaactaccaa gttctaatta
     9961 tctagagttt ggcagtttct catttacaca acatattttt cttctttttc gattttttca
    10021 tagtgctttt gttcatcatc atccgttata actactgtta catcattcag attataatat
    10081 actgaaaaat ctcttttccc aattttcgaa tgatcaatca ataaaaagcg ttcaacagaa
    10141 ttattcagag cgatctgttg agtttggccc tcttcaaaag tcgaagtcat aattttctgt
    10201 tcatttaaag cattacagct gaaaaatgct ttatgaaaat tcatatcctg tagcgattta
    10261 ttcgtgattt caccaacaaa gcattgagtc gtttcccgca tctcgccacc taatagatag
    10321 atttttcgat tcccttttcg cttatttaat tcttcaaaaa caggcaaaca gtttgtaaca
    10381 atccgcagtg aatccccttg aatgattttt gacatgagct cgattgtagt tcctggtcca
    10441 agaaatatcg tatcaccatc attgatcatt tcattcgcct tttccacaat ccgctgcttt
    10501 tcttcttgca gcataatctg tttttctcta tgagaaagct ccacatgccg ataaaaatcc
    10561 ttcaatttcg ctccgccatg gacgcgttct aataatcctt gtttctccat ttcgtccaaa
    10621 tcacgtcgga ctgtcatatc cgaaaccgaa aacttctcca taatatcgct gactcgtact
    10681 gtaccgttaa cctctaataa cgacatgatc gcttggaatc gatccgtttt taacatttca
    10741 tcgcctcttt tctttttaag actatcaaat tcttaagaaa agtgctagaa caagttttct
    10801 taagaagcct tctgcaggaa ggaaagcaaa atttttcaga atttgcaagc tgctattcta
    10861 aaaaataaaa ccgaacgagc atgactgtca tagtgacagc cttgttcatt cgacttttat
    10921 ctttaataaa tcattttatt taatctgaag ttattgtgca agttcaaaaa caaagtagtt
    10981 aatgtctcct cgatatttcg aaatcgaata ctcaacgggc agacgttcta gcgaaaaacc
    11041 ctgtgtatgg aaatagaaca ttggatctcc ttcttccaca tctaacaaat cgctgatcgt
    11101 atcatccgct ttgattactt ctagttttct ggtgaccgtt ttaattggat aacccatttc
    11161 ttcaaaaact tgatacattt tttcttttct gatttgtcaa attaagctag acaatatgtc
    11221 tttatctatg cagctcaaaa atacttccaa tggtgttcga taatttaatg attttcttgg
    11281 aatatggttt cttttcgagg caacggattg aataaaggtt tcatccatgt ccctaaagtc
    11341 cattgtttta ggtaagccat ctcgtctaag caagccgttt gagtgctcat ttagccctct
    11401 ttgcgaaggt gttcctggat ctgcgaaaaa gatggcaata tcgttcgagt tacttataga
    11461 tcgccagttg gaaaattctt ttccacaatc aaatgtcatg gatttaaaca agtgtttagg
    11521 catggatttg aaccaatcat ttaacctgtt ttcgatatct tcggctcgtc tgcctgtcgg
    11581 tttcaaagta ataataacct tggataaaca ctcaaccaat gtaataacag cgctcttgtg
    11641 tttaactccc acaatggtgt cgccttcgag atgaccaaat tctttagtca ggtgtggata
    11701 gagactgttc cgttcatgaa tcgttctgcg aaaggcctgt tttccacgct tttcttgatg
    11761 attattcggt ttacgtttcc ccttcatagg taacgactgt gtgtcaaaaa ggcctttttt
    11821 aaacatccga tagagtgtac gaacagaaca atcaattgga aactcgccac ggccgataat
    11881 cacatcgggt gaccaccctt gagctacctt ttcttgaaca tatgttgatt gttcatcaga
    11941 taaaacggtt gaacgtcgtc cacaacgaga tttattttgt ttgtattgac ggtaataatc
    12001 tagcactttt ttccttgttt gagaaacgaa taaacattat aaatggtttg tctagagcga
    12061 tttaaacttt gtgcgacaag agcgacaggt ttctcgatat tgaaataaga ctctatgatt
    12121 actagttcgt ctgttgtaag atgggtgtag gtcatttgta ctcactcctt attaattctt
    12181 tggtcggaac tattttgagt gtagcacaaa tgatcttttt agttgtctag cttaatttta
    12241 caatcgacgc ctcaaaaaga atacccgaaa tttaaacagc aaaaaaagat agcgcttacc
    12301 attgtgttta agataaaacg ctagctaagt tggctagcgc tttattaatc taagcaagct
    12361 ctaaaattgc ttcaatacaa aatcaactgc tcctttagga tcacgtgtta aattgatata
    12421 ttctgcacct ttagttgcaa ttacttttat ccctaatttg tctgcatctt tacggagatc
    12481 atccaaatag gaattcactt gaggtgctag aacgattaaa tcaaaatttt tcatcatatc
    12541 ataatgagaa cggttctgtt gcaaagtttt aaatctacta tcaaataagg tagaataata
    12601 gaaaaagata gcaggaggaa tgacgatgaa tcattttaaa ggaaagcaat ttcagcagga
    12661 tgtgattatt gtagccgtgg gctactatct tcgttataac cttagctatc gtgaagttca
    12721 agaaatctta tatgatcgtg gcattaacgt ttctcatacg acgatttatc gttgggtgca
    12781 agaatatggc aaactactct atcaaatttg gaaaaagaa
//
LOCUS       DAKCAA010000072        12004 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000072 DAKCAA010000000
VERSION     DAKCAA010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.073"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            433..1656
                     /locus_tag="OUE31_002273"
     CDS             433..1656
                     /locus_tag="OUE31_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HCU0223250.1"
                     /translation="MESYQFQVFKLVPSLERRGNRMKITEKNVNPKFETTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            1691..2458
                     /locus_tag="OUE31_002274"
     CDS             1691..2458
                     /locus_tag="OUE31_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCU0223251.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFKDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            2647..3045
                     /locus_tag="OUE31_002275"
     CDS             2647..3045
                     /locus_tag="OUE31_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HCU0223252.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(3352..3726)
                     /locus_tag="OUE31_002276"
     CDS             complement(3352..3726)
                     /locus_tag="OUE31_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223253.1"
                     /translation="MKQTQTETINDTLADQLAGYYKLFEMSKAQRLIHYLWKYKILFL
                     FWEATLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
     gene            complement(3748..4125)
                     /locus_tag="OUE31_002277"
     CDS             complement(3748..4125)
                     /locus_tag="OUE31_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223254.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVETLSESLTNALNLVKK
                     AKLLFEFQSDYHNELLAQSEILD"
     gene            complement(4115..4510)
                     /locus_tag="OUE31_002278"
     CDS             complement(4115..4510)
                     /locus_tag="OUE31_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HCU0223255.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            complement(4577..4762)
                     /locus_tag="OUE31_002279"
     CDS             complement(4577..4762)
                     /locus_tag="OUE31_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HCU0223256.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            complement(4844..5098)
                     /locus_tag="OUE31_002280"
     CDS             complement(4844..5098)
                     /locus_tag="OUE31_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223257.1"
                     /translation="MNYTDEEQITLEYVFIDEEGEEIEKVLIISSKDLENALTYEPYE
                     STVTVNEFLDTYTSDDTWEIMNICNANNIQFAEKNNKSFY"
     gene            complement(5120..5365)
                     /locus_tag="OUE31_002281"
     CDS             complement(5120..5365)
                     /locus_tag="OUE31_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223258.1"
                     /translation="MWTLEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTS
                     LECVWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            complement(5372..5656)
                     /locus_tag="OUE31_002282"
     CDS             complement(5372..5656)
                     /locus_tag="OUE31_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223259.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            complement(6147..6686)
                     /locus_tag="OUE31_002283"
     CDS             complement(6147..6686)
                     /locus_tag="OUE31_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223260.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVDTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKRQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVA"
     gene            complement(6799..7065)
                     /locus_tag="OUE31_002284"
     CDS             complement(6799..7065)
                     /locus_tag="OUE31_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCU0223261.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            complement(7067..7288)
                     /locus_tag="OUE31_002285"
     CDS             complement(7067..7288)
                     /locus_tag="OUE31_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HCU0223262.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            7508..8326
                     /locus_tag="OUE31_002286"
     CDS             7508..8326
                     /locus_tag="OUE31_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCU0223263.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            8330..8626
                     /locus_tag="OUE31_002287"
     CDS             8330..8626
                     /locus_tag="OUE31_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223264.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(8808..9161)
                     /locus_tag="OUE31_002288"
     CDS             complement(8808..9161)
                     /locus_tag="OUE31_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223265.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(9181..10236)
                     /locus_tag="OUE31_002289"
     CDS             complement(9181..10236)
                     /locus_tag="OUE31_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HCU0223266.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNISEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTVNLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDESLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            10452..10850
                     /locus_tag="OUE31_002290"
     CDS             10452..10850
                     /locus_tag="OUE31_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223267.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KVAVEKYFDSLEESAKEIFNGEKAGSYELDGIKFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
BASE COUNT         4060 a         1829 c         2009 g         4106 t
ORIGIN      
        1 atatatattt taatctttaa aactttagca acctccaaaa aggctttata tcaatcttaa
       61 atagatttta gggtggacat aaagcgatgc gaacatggac aaaaagcgat gtgaatgtgg
      121 acaaaaagcg atgcaaacgt ggacaaaaag cgatgtggta ttccgaatat atccaaaaaa
      181 agaaaaagta tgtgaattta tttctaaaaa ctagaaaaat atttgttttt taattttggt
      241 aatttttata atttcgtatt ttattgaaaa ggatttttat tttgaaaatg ttctaaaata
      301 gcgatttctg ctgtattttc aatgaaattt gattggaaaa aataaaatgt gttttactga
      361 cattgagtta tgttataaat ttacgataca tttcttgttg taacgtatcg aaaacaggtc
      421 tatacttatt caatggaatc gtaccagttc caagttttta agctcgtacc aagcttagaa
      481 agaagaggca atcgtatgaa aataacagaa aagaatgtaa acccgaaatt tgaaactacc
      541 gaaagcaatc taaaaaagtt tgatttaact gttactttat cgaatcaact tgtagatagc
      601 attgttgaaa tggatgctat gccacaaaaa atttatcttt acgctatagg acatcttgac
      661 cctaaaaatc cgccttttaa taataccgtc aaagtatcta aaaaggcttt atttgcgttg
      721 atgtcttcta gttcatcttc ttcaaaacat tcaagattaa aacaagttat tgaaaaattg
      781 catcagcaat ctgtcattaa aattcaaaga actaaaccta acggtaagac tgaatacaaa
      841 gtcatctcac cgctagaaat tactgaattc aatgattttt ctgatgcagt atctattaaa
      901 tttagtagtt caattatgcc tttattaacg aacttagaag atcattttac gcaatataca
      961 tttgatcaag tagttaactt gacaagcaag tatgcgatca gtttttttca attattcact
     1021 aaagatttta atctgtatga agcaaataga gataacttaa catggagtac aaaatcactt
     1081 gatagattaa aaaatcctgt tttctccatt gcagatttac gaaagaaatt tagtattgag
     1141 aaaaaatata aagcttttcg agactttgaa agacgtgtaa ttaaagaacc gattgcccaa
     1201 ctgaataaat acactgattt taaaattgac tatgagctta tcaagaaggg tcatacttat
     1261 acaaatataa agttcttgct tacacgtacc atgtcagttc cggtacctta taagcaagaa
     1321 caaagagacc ctgcttattt aaaaggcgca gaagataaaa cagagaaaat gaatcaatcg
     1381 tacttgaaag ctatgaatag caaatacact aaattactaa tcaaaaactt tttgatcagt
     1441 tctgccgact tatgcgatct taaacttatg agccgacttc agaataaagt ttatccgctt
     1501 tatgatcgtt tatccaaaga tagaggattt gaatcagttg tcaatcacct atcttacgtt
     1561 gctactcata aggaggatta cacaataaaa aatactgtta aatatctcga aaaatcaatt
     1621 acgagttatt tgccttatgt gaacctttat gattaacaac tgaaaacatg cgtgaaggaa
     1681 ggaaaaactt ttgaaaaaag atgaactgac aaagtacaat gaggagttct tagcaacaat
     1741 tgacatgaaa atggatttaa agtcgtatga actttatcaa ttgctgttca gttatatctc
     1801 acccacaaag ctaaagaaaa caggcgtagt agatttacct gttaaagcga ttattaatta
     1861 catggatgtt gatcaaaatc ttgaaacgga actaaaaacc atagttaaca ctttacaaag
     1921 acaagcagtt tatgaaatat cgaatctaga caagaaatat aagacgtata ctactgtatc
     1981 tgctattgat cggattcatt gggatttaga agagcatagt gtatctttca gtttttcaga
     2041 agatgtaatt cccttaattg tctcaatcaa aaagaagtat ccgttctttg tttttaaaga
     2101 cttagcatct tttcaaaaaa aatatagcat cgtgttatac aaatatttgg cgatgtatta
     2161 taaaaaatat cttatcgcca aaaataaagg agattttgag aaagctgaaa tatataagaa
     2221 tcccctgatt gaaatagtta aaattcgtga gattacgaaa acagaaaatg agtataaaac
     2281 aatatcgaat tttgatagac gtgttttaag ggaatcagtt gaggaaatta atgaaaaatc
     2341 aatgctgaag attgattttg ctaaagttag aaaaggcaga aattacaatt ttgctgtcca
     2401 gtttaatatt tctagtgagt ttgatgaaaa accttataga gaaaaaaaat taggttaatg
     2461 caaaatatat cttactcgtt tgaagatgct tcagacgtat gctaagatat gtagtgcctt
     2521 gggagcaagg tattaatctc ctttagaggt taattagctt gtgatcgcct atcaattttt
     2581 ggtaggcgat tctttttttg aaactaaaaa gcaaaaatta ttttttaatt agagaggtgc
     2641 aatgcgatga aatacttttt ttgtgcagta ttcgaatgga aaggaaatga atatgcagtt
     2701 aaattcccag attttccaga cttatatacg catggtgaaa ctttagaaga tgcttttgag
     2761 atggcgcaag aagtattgga aggatacttg gtgcttttag agttgcaaga aaaagaaatt
     2821 ccatcgccta cgcctgttca agagttaaat gcaagaatca agcgatctga gaatgttaat
     2881 ttatttgtcg taaaagctaa tacgaaagtt gctaaagctc gaaacaagca aaattatgat
     2941 cgaaaatcag tgactgtgga acactattta aatgttttag cggctgaaga gaatattaat
     3001 ctgtcgaaag ctttgaatga tttgttgaga gaaaagttga tttgatgcct ctcagatgat
     3061 catattaagc aaaaacagct tgttttagga cgtatggatt taagaaagac aaattatcaa
     3121 agaatatatt aaaagctctc agaagccttc tgagagcttt taaattgcta tgtattgtac
     3181 tgcatctgct caaattgatt ttcttttcat gcttatcatg tatctagttt tccatcaagt
     3241 aattttttag atatatattg agtaataaat agcaaatttg cttgatataa gctcgaatta
     3301 ggtgctttgt aatgtgttag gataaattat acaagaaaat gtcaaaagct ctcagaacgc
     3361 ttctgagagc tttttatcgg taggcttgtt taacgtgatc ttgaaagata cccttttgat
     3421 gtttctctcg atccctgcat cgctaattac taagtgttct tcaagtgtga tgtaggtata
     3481 taaattaagc atcaaaatgg tgtagataag caaaaaactc cctaaaacta agtgttgatt
     3541 ataaaaatct gacttataaa aaagaactga gaatgttagt gttgcttccc aaaaaagaaa
     3601 caaaattttg tatttccaaa gatagtggat caatcgctgt gctttactca tctcaaataa
     3661 tttataataa cctgctaatt gatcagcaag cgtatcgtta atggtttctg tctgtgtttg
     3721 tttcatcttt ctcttctcct gtttcaatta atctaaaatt tcagattgag caagcaactc
     3781 attgtggtag tcggattgaa attcaaataa caattttgcc ttcttaacga ggtttaaagc
     3841 gttcgttagt gattcactta atgtttcaac atctttaact gattttgcat gtttcatttt
     3901 ttcagtgtgc gtatagcaga attcaggtat tgagttaggg gttgcctgtt caataaacat
     3961 ctcaattcgc aagttattat cctcaaaaat aattagatca ttggcaaagt gtttggtact
     4021 aacgctaatg ccagttgtat cttttaatag attattgatt aacgttcgag agaaatagtt
     4081 taagtgtgta gctttcatag gttcggtctc ctttttactt ttcaagcaac tcttcttcta
     4141 gtgctttttg aagtagttga gagaagttta tgtttttctc cttccctaaa agaactaacc
     4201 attccggaac actaacattt tttctaattg tttttgtatt taagcttctt cggaaaagtt
     4261 taatgtttag ttggatgatt actaccactt gattggcttt caaagttaat tcttccactg
     4321 ctgatggttt aggaaattct gcatctggta cactatatag cgctaatcct aaagcatcct
     4381 tagcgtttaa atatgcttct tcaagactat ttccaaaggt agatatttcc ggtaagtcag
     4441 ggaaaacgat gttataagct tctccttctt tctcgaagat tgccggataa aaaatatttt
     4501 ttgtcttcat ttcctcgctc cttttctagt gtaagagagg atagtatgcc taataccaaa
     4561 taggaaggca aggctgttaa agccctgctt gcttccagat attagcttct gttcctagtg
     4621 gtacatcacc attgtggatc ggaacaacga ccgttctttt agtcttggaa ttataaaatt
     4681 ttgcatgact gccagtttgt ccagtctttt tgaagccgtt agatttgaga atttttacaa
     4741 tttctcttgc tgtcttaggc atagctaccc tccctttaca aaacctatta tacacattgt
     4801 tgtgtatgga atcaatagaa aaagaggatg ttttattgca aaactaataa aatgatttat
     4861 tgtttttttc agcaaattga atgttattag cgttgcaaat attcatgatt tcccaagtat
     4921 catcagaagt ataggtatct aagaattcat tgacagttac ggttgattcg tatggttcat
     4981 aagtcaaagc gttctccaag tcttttgatg aaataatcaa gactttttca atttcctccc
     5041 cttcttcatc tatgaaaaca tattctaaag tgatttgttc ttcatcggta taattcatat
     5101 tgtgttctcc tttcttgtac taagaaaaat ggatatttcc aattgcatcc cactcggcac
     5161 cattgtggta taggacgtga ccgagcgtta cgcctttgaa atgttcttct aaatacatcc
     5221 aaacgcattc aaggctagta cctgctttga gattgtagaa gtctgcatcc aatacctttt
     5281 cagaagttat cggatcaatg cgagttggta cttcaataaa ttcagtccaa atttctgcaa
     5341 aagtcttacc ttccaaagtc cacactccct atcaattaat tccaaaagca aatagagaaa
     5401 tcaagcgacc gtcaatagtc acttcaacaa ctgaaaatgc cgttgaaaca gttttaacat
     5461 ctacactttc caagttcccg atgaaggaat ctttgtgctt tagaatagct ttctttagct
     5521 gtctgttata cgcttgccga ctgttaaact ttttgaattc tcgatccttg atcagctgtt
     5581 taacgatccc tgcattaatt gtataacttt ctgcaatagc aacgtgagta ggttgctgta
     5641 aagtagctgt tagcatcttg tcactccttc ctaaaagtta attagcttgt ttacaaatac
     5701 attatacaca tcagtgtgta taatgtaaag agaaaaaggt gctaatggat cagctgttct
     5761 aaacaaaaga aaacgataaa gtaacaaata aagtcagcaa agttaaaaag gatgaaacgg
     5821 ctagtctggt tgctttgctt gtgtgatttt cggctttctt atagatcaaa taggaaatta
     5881 tcagtgatat tccagtaaag aataatgtac tagctgtcac taaaaggaat aggttaatca
     5941 tacgatacac tccttctgta atattggtat cagatacgtt taaatgcgtt tctgagctgt
     6001 tttggatcag atggtgatgt ttttagccct accctaaaaa caaagcccag aaaagaattt
     6061 aaaagtgttc gtacctaata cgtttatatt catatacata tacataaaca taaacgtata
     6121 cacgtttatg tttatgtatt taagttttag gctacttcct taacatctcc tgctgatagt
     6181 cgagtgaacc gagtgagtga tccatcttgt agtcgaaaaa taaagctacg tttgagttta
     6241 tactgataga cagcgacata cgatccatcc cagattgagt aagttttacc tgcaactaat
     6301 aagtcatcaa gttttggttt attgctttct tctttaattc tatctagttg tcgcttaacc
     6361 attttttctt gatcaccgac aaagaatttc aaccattttt tcggaatttt cttaaagtaa
     6421 gcaggactgt catttaagaa gtagattggt ttgtacattt catctcgaaa gatgaagctg
     6481 tcaatatcgt aggttccttc tgcatctttg aaaaggataa ttccataggt cttcgttact
     6541 ttggtatcta cgatttccaa accatttttg gcgtaccctt tcttttcttc gatcacttca
     6601 tttgctgatg aataatcacc ataccatccc ataaaaaatc gctccttttg aaagttaatt
     6661 agcttgttta cacttatatt atacacaccg gtgtgtataa tatcaagagg atattgttct
     6721 tttttaggta aagtgggatc gtaaacagtg attttgttgg gttaacaaaa aaacagacaa
     6781 gccttatcag cttgtctgtt acttataaac ttcacttctg tgaccaatag acaatataag
     6841 aattgtcact tcatgctcgc taatatcagc tattatacga tatgcaccta ccctatatcg
     6901 ccagtagcct gatttattag ctgttagacc tttaccatgc tttcttggat catcagtgcc
     6961 tacaagattt ttctcgatcc agtttaggat aacctttgcc tgaaacttat ccattttttt
     7021 tagcgctttt tgagcttcac gttcatatct tacttggtaa gtcatcttat aagcctaact
     7081 cttttagcat atcttcgtgg gaaatacttt gatcgttttc ctcatgctct ttcattagtt
     7141 gcttgtaggt ggcaaagtct actaacgttt ctgctgtttg cagggaatta ctacgcataa
     7201 attcagaaat gttatctccg ttgaattcag caactttttc aagaaaatct ttttcttctt
     7261 tagatacacg aatacttatt actggcatag tttatcaact ccttttcaat tacattgtac
     7321 tacgattgta tgacaaatgc aatagttata tatttgaata tatacacaaa catatacata
     7381 tatatgtttg tgttgtagaa tataaaagca aatataaata taaacacgtt tatgtatata
     7441 aacatataca taaacgtgtt tatagtgtat aatggagtta caaaaggtta ataagggagg
     7501 tttaatcatg gaaaagaagt tgtcaatcat tactggaaac attgaaaaag gtggaacagg
     7561 taaaacaaca acaatctaca atctaggtgg atatgctgtc gaaaatttag gtatgaaggt
     7621 gctgtatatt gatgaagata agtcgcaaaa cctatcaaaa cgatttcctg atgctttcag
     7681 taaagcgaaa agagagaata caatcaatca tttatatctt catggatcag ctgaaccttt
     7741 agctataaat gagaacatgg atattttagt agcaggtgaa gatttaaaac aagttgagat
     7801 gcaaatgcgt gatatgccta acaacagaac cctactgttt agatggatcg ttgttaacta
     7861 tgaacagctt aaagagaagt atgatctaat tctgattgat actcataatg atgcaggtct
     7921 actagctcaa aatgcttggg ctgtatctga tcttgtcgta ggcatttctg atccatctaa
     7981 agatggtttt gaagctttgc tgaagcttgg taaagatatt gatgcactag caaaacagtt
     8041 gattgatatt aagactggtg aaacactgat ggaaactaaa tacgctacga tcggtagcag
     8101 gatcaaacat aatactaatt caagtcgtga gttcctagaa ttggtaccaa cgttatctaa
     8161 ttatcttgga tatgtacaag agaaggaatt gcttaatgca actagcttag aaggtaagaa
     8221 tattgctgag ttcgctaagg ataagaatat ctatcgtaag aataaggatt tctttgaaag
     8281 cacgtttacg ctatacaaca aaataattga tacggcacaa gaataaggag tgattgaagt
     8341 gaaagaaaat agatttaaaa aattcgctga agctgaagta gaagaagttc ctgaagtggt
     8401 tgaagcagtt gaagaaccta aacaaacacc taaagaaaca acaagttctt tggtagctaa
     8461 actaaaaagt gatagttctg aaaagaagaa aaattatcaa ttcacgcttc aaccatcaca
     8521 aagaaagaaa ctatctaaaa tcagcgaaaa gttaggaatt cgatcagatt cagctttact
     8581 tggtgaaatg atagataact tatatgatga agtttttggt gagtgatcag tttaaagctg
     8641 atcacttttt ttattggaat aagcggttag gtatagctta actaaatttc gtatacgtgt
     8701 ttatggatat atacgtatac atgtttatat acatgtatac gtatatgttt atgtttgtat
     8761 ttgtacataa taaaaaggct aggtattgta acctcgcctt tttattttta aagtaagtct
     8821 ttgttacttg gtgcattgaa cccttttagc attggctttt ctttctttgc tgaatgatcg
     8881 gatgtaaccg ttgaaggatg ctcttgttga atagggttat gatcagttgg tttattcttt
     8941 acttctgcta ctttgctatc gtttctatcg ttgcctgctt caataattgt aacttcattg
     9001 ttctttacac gccgatatag attcaaagct tttttgatcg tctgagagta tttaacgcct
     9061 agtgtttcat attcagattc aagaaactct gctaaaggta actcgctaac cttttctcta
     9121 ttgattataa ctacataacg ctctgatttt cccttattca tgttgatctc cttcgctgtt
     9181 ttattgagtt aaaccaaact tgtaaaagcc ttttacatta gaaaattcac tgtcttcaac
     9241 aaacaaggta tgcggaattt tatcttttac aagttgtttg tcgataatag aagccccacc
     9301 accagtaaag acaactttat ctaaggttgt gaagtttttg aatgtagcta aaacttctgc
     9361 aacaaccata ttggtgtatg tttttatttc tctttcaact acttctgaaa tatcaaaact
     9421 ttcatttccg cttggcttaa atagatatac gcctttttct ttgccttctc ggataatctt
     9481 ttcaagttgg aaagcattag gactgatcgg aaggtcaagc atatttacga tacgattata
     9541 taaagtaaaa ataccggtat ccttttgttc acggttgttt tcgtcaattt caaaattttg
     9601 gacaacatca aaaagtttcg tgccaccacc aatatcaaca aaaccgatct tctgactgat
     9661 caatgattca tcttgtacac taccatcatc agcaaggagg aggttatata gtgttccaat
     9721 cggctgtggc agtacccaaa cggtatctac gtttatatta taagctttac cgtcaacttc
     9781 aactgaatgt tgtcgtgtgg cttgttgcat cacgtatttg acgattgttt cggtatagtc
     9841 ggatgaaggc agacctaaaa ctagattaac ggttaaaacg tcatcagatt gatcttctaa
     9901 acgtgctagg ttagctaaag agaaagatag gatattttgg taggtttcct gcttgtatct
     9961 gctgatccca aaacctagtg attctatcac gtagtcatct tttcctagct cgtgtatatc
    10021 cttcccaaaa taatagcttt cagtagtgtt tactaggcta tattcagaaa tgtttagtga
    10081 tcgttttaat gaggaaccta tattagaaaa acgtcctgaa ttaatgatat ttttgttcaa
    10141 aatacgagag ggaagcgaga gtggagaaac gtgtgtactc atttctttta ctgatttatt
    10201 ccctaagtca acggaaaaca ataatggttc tttcatggta tgacctcttt ctgtttgtgt
    10261 ttatggtatt tcggtacgaa aatagtttac acctatttac taatagttgc aactgtttat
    10321 aataaaaaaa tgcaatcaaa aaagtataat caattacaat aaagtgtaag taaaaaggtg
    10381 taaataaaca cttgcaaatt tatcttatta tgatattata aaaacataaa ttatattaag
    10441 gagtgatcct gatgcgattg agaagaaata agaattacac tactattatt ttagaagatt
    10501 ttactgatca agaattactt attgtcggta aaacaaaagc agattttatc gaaaagggaa
    10561 atgcttcaat agtaaaagct tcaaaggttg ctgtcgaaaa atattttgat tctttagaag
    10621 aaagtgctaa ggaaattttt aatggagaga aagctggtag ctatgagtta gatggtatta
    10681 aatttagctt gatcccaaca actgaaaata ttattccgaa gaaattatat tatatctttt
    10741 catctgaaaa acatacttca atgaagcctt gcatttttga ttggcaatgg ttgattgatg
    10801 ctgtattgga tgtaaaatgt tcaaaataca atattacttt ggggtgttaa ttatgagtat
    10861 gctagttaga aaattaccat tatctgtaag agaatttcta ttttacttgg tctgcttaat
    10921 cgcatcaggg tttaagctga tcgaacatat ttttatcttt gcttatttat tagcaatgat
    10981 cgcattttta tctggtggtt ggttaattat atatttgtta agctaatttt tagatcaaaa
    11041 ataattaata aattaaacga taaaataacc gttgaaaaat gtaattcaag gacaacacct
    11101 aacaatcagc ttgtaatcaa attataaaat aacataattc aataattgat gctttttaaa
    11161 ggacaaatta agtgtatcaa cataaacgtg tatatgtata tgtttatgtt gatacttttt
    11221 ttgtcttaat ttttttattt ttaaattcta tttactaatg ctgtgtaagt agtgatcaga
    11281 aaaaacaaaa tagcgaggtt aagctattta ttagttcata tattatattc agattaatat
    11341 gatccaatat taatctgaag gtgaaaccaa tatatttcta tggattcatg taaaattatt
    11401 tagatgttcc tgctaataaa ataacaaaaa taaaatattc agctatttta taccattttt
    11461 cgataacatt attctgtttg taatattaaa acatttaaat tttgaattat ttttctaaat
    11521 tagatcaatt tatattctta caaaacagta taaaaaatgg tttttatatc gttatttatt
    11581 gatattattc tcataaaaaa caatgaaatc gcatactttt atgaatgatt aaatgtaatt
    11641 ttaatacata taccaattaa aagagaattt ttcatatttt cacttaaaaa tttataaaaa
    11701 aacaagataa ttgatacttc gattttgcga acattttgcc ttcccgccta atacagcttt
    11761 aatatcatga ttatatcagc aacaaatcgc ttttttagat aatttaagca tcaaataatt
    11821 atccttaatc agggtaaaaa ataacgaata aatggatttt gggaataggt aaaaactaga
    11881 tcggtttctg acgaaaaata acatgaaaaa ggaaatataa aataacatgg agcgtgggac
    11941 gaataaagaa attttacaca taaggggcgt agaaatgtaa agaaacttaa cacaaaacaa
    12001 aagt
//
LOCUS       DAKCAA010000073        11473 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000073 DAKCAA010000000
VERSION     DAKCAA010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.074"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            162..962
                     /locus_tag="OUE31_002291"
     CDS             162..962
                     /locus_tag="OUE31_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HCU0223268.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKVSGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTQNLGMIKEK
                     DEEEMLWKVDGIEYVLDKAEHLVKNAKESLLIQVWHENLTDSLLKTLQQAEKRVDKFV
                     LILFSSSHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESSEELKAKYGEDFEGIRKIY"
     gene            978..1856
                     /locus_tag="OUE31_002292"
     CDS             978..1856
                     /locus_tag="OUE31_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCU0223269.1"
                     /translation="MIRNILLALIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFITFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGVKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAAFLIFMGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFDEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYVLKWIVILVLLYS
                     AYTMLGSQLKKVSAAN"
     gene            1869..2849
                     /locus_tag="OUE31_002293"
     CDS             1869..2849
                     /locus_tag="OUE31_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HCU0223270.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENLKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFDRASRFAEEMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVNKAKENNLGKLIY"
     gene            3371..3589
                     /locus_tag="OUE31_002294"
     CDS             3371..3589
                     /locus_tag="OUE31_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223271.1"
                     /translation="MNFFQNVFTDFVGDFKYLIMLAMLGGAAYIAFERKASKAIPLIL
                     VLAVAVWLVGDTSGVFNWILDRMRSWGR"
     gene            3528..3914
                     /locus_tag="OUE31_002295"
                     /pseudo
     CDS             3528..3914
                     /locus_tag="OUE31_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382919.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            3973..6510
                     /locus_tag="OUE31_002296"
     CDS             3973..6510
                     /locus_tag="OUE31_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCU0223272.1"
                     /translation="MRLPKLVPKIPFYYLEDNLVFGEEDRVYAYYEFPMYSYSFVGED
                     QAYQLQQAIMRLIRQSHSSHVRFFFCTNEEKIEKTIKSSKELVRSKGELKTIAYQHLE
                     GVQHILEELHGKYIQNVCWYVGIELVLEEIAPKEAHWLKEFRIAAKDFFHRSNARLFG
                     DFETIPNEKIQRYKRLENLLYNRISKYFRLRKTTPEDMVFLVEHLEGKKEQSLDEVMY
                     RPNSFKEETNTYTYHYDVLNLASAGITEKKNYLILEQGTEKEYITYLSLSRMTRDLVF
                     PFQSEIYYFLQSELDFPIDSWLDVNLLDNRLALAKVRGKKSDLSDIYESGMSVGKDVG
                     NNVREAYQSANELEQKLEDTREDLYVLSLNVRVSGKTYDEMLKRVSDVRNFFDVYSMY
                     LEVPCNVQLLLHFGSYPAGRRVIEDYRQYVGAEFIASLGIGATQQLGDGCGIPIGFNA
                     ETGIPVFIKPWLAAQGIKGTVTNTLAKALIGSLGGGKSLTENLLLFWSVLFGALAFCI
                     DPKSERSNWSEDLPYFAPYLKTVNITSEKENIGLLDPFQLMRRKKDQESLALDVLTYI
                     TGVSIRDEDRFPLLQRAVKTVSDFEGTKGLLLVIQELYAQEAATAQRLAKHIESFKEL
                     SIAGLLFGDGTNQQGLNLDAKCNLALVQDLTLPDSETVPEDYNSSEILSIAIMMSLAT
                     YALDFIKQNRKIYKAVGLDESWAWLNVAQGKILGDKLVREGRSRNAGIDFSTQNTDDL
                     GDEKMRSKIGLKFIFRSNDREEITKALSFCGISVTEENIQRVKNLENGECLFCDIHGN
                     IGILYVYYWFEDLFHAFDTRPPMEETYEEEEYKDEILEKLVEEIEVN"
     gene            6511..8532
                     /locus_tag="OUE31_002297"
     CDS             6511..8532
                     /locus_tag="OUE31_002297"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223273.1"
                     /translation="MKQWYSKVSFLITRRKLVFISLVIMMGVFFFHPSLVEAAGWIKE
                     TLGGKNAVYDFETYPLDNYNLDFFVDTSWNWLPWKWGEGISNTVIYGIFAVTNILWML
                     NVYLCYFLGFLVQEAFELDFLSELIGSLSHTIQNIAGMNRTGTLSHGLVPFFGGLLIT
                     LAGCSVVYQGIVKQHPTQAIQQAVTFLFTFICCGVFFMNTNTYLEKANGVQKEINSEM
                     LTIAKNLLPEQKEKPDAIKAIRENLFAIQIKQPWLVMQFGDSDIKTVGEERIINLLKE
                     SPYDEGEQRNKLVEEEVTKQKNGHLSVQKVYLRFGMVFLTLIVNIVISMSVLVLIVIL
                     IASQVLFLLFIGFLPVAMIFSLFPNSGSLLGNALQKVFQLLFTKMGILLILTITFSIS
                     HELNHLSKDKGMIWTSFLQVTLWLSVSTRVNELLGWMKIGGVQTRAGDRTGRFLRGMM
                     LGTMGQKMIRGIGENFVGGTAGGVAGQMISKSMSGQRSIASTPLIERVGKKVSAMTEL
                     PATIESRAEQWKRTIQYVPTNAQYKAQKMKYDYFSGRMNESERQTRARNLANERQKNF
                     YEARKDALQLEQQERKQRAMRSMAHQTGKTQVTSGKLQTRKSAMIGRTEQFPTIEKRS
                     NISNIAKNKKLSKQEHPIHERSTNRKIETPVRWTSTSRQNARKGRTKKE"
     gene            8679..9467
                     /locus_tag="OUE31_002298"
     CDS             8679..9467
                     /locus_tag="OUE31_002298"
                     /inference="COORDINATES: protein motif:HMM:NF024056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCU0223274.1"
                     /translation="MVFSVCFGVYNNLTSQDTHTIHETKVIDKQLKDMTGIESYVKNF
                     AFLYFTVSLESDQQINRSKAVESYLADGLQMDNEIDKDIETNVKVKNVSIWAIEEHES
                     KKHTFVVMFHVLLEIEKEFKERVYKVEVYRNELSYAIVKLPIVASNVKKATIKVDTRF
                     ETTSISRKEQEELEKFLYTFFRIYPKANAEELKYYGTTLLPIQQPLAFEELSNLQVAK
                     KEGRYEIHCNILYQDQETHLWFTMYYEMSMKQLENGNFRIEAIH"
     gene            9596..10558
                     /locus_tag="OUE31_002299"
                     /pseudo
     CDS             9596..10558
                     /locus_tag="OUE31_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
     gene            10900..11121
                     /locus_tag="OUE31_002300"
     CDS             10900..11121
                     /locus_tag="OUE31_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223275.1"
                     /translation="MKENGIDNDPHIQYKTIGRIHTITQDVIQSDQYLLFGEETTNEI
                     TRFVLLQIKVDQEVQKIDKIKIYYVRSAY"
     gene            complement(11240..>11473)
                     /locus_tag="OUE31_002301"
     CDS             complement(11240..>11473)
                     /locus_tag="OUE31_002301"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCU0223276.1"
                     /translation="ETPVTPENPEPDKPVSLKNTNSKILISEKNVSNTNSKSNNTLPQ
                     TGEKESSGVLAGLVILLASIAVGIKLNLKRKNI"
BASE COUNT         3841 a         1723 c         2446 g         3463 t
ORIGIN      
        1 tcttcacaaa cattcatata ataatagttt tatttaataa atacattgtt tttaaactaa
       61 tttctatatg tgttttgttg aactaactct tgacataaaa tttaaaagga tttatagttg
      121 ttaccgtagt agctactaaa agataaagtg aggattaatc aatggaaacg attattcaaa
      181 tcatgaaaaa atatgatttt tcagagatgg aaacaagagt gtataccaca ctattggaaa
      241 aaggcaatct tacaggatat gaagtaagta aagtctcagg tgtgccacgc tcgaaagtat
      301 ataacatttt ggaaaaacta ttaaaaaaga atttgattgt cgtcaataaa tcagaaccta
      361 aactttatca tgccatctcg gcaaatgagt ttttagagaa attagaaaaa agtgttaaaa
      421 atgatctctc ttttcttact caaaatctag ggatgatcaa agaaaaagat gaagaagaaa
      481 tgctgtggaa agttgatggc atcgagtatg ttctggataa agcagagcat ttggtgaaaa
      541 atgcaaaaga aagtttgctc atccaagttt ggcatgagaa cctcacggat tcactgctaa
      601 agacattgca gcaggctgaa aaaagagtcg ataaatttgt actgatttta ttcagttcta
      661 gccatgaata tgatcttccc ttagaaaagt attacattca tggttttgaa acagacaaac
      721 tcgctgactt tggggcaaga tggataaaca tcgtcgccga tgagcaagaa gtcgtgtttg
      781 gcaccattaa cgaagaactg caatcaaccg atgtcacttg gacaaaaaac cacgccatgg
      841 tcaatctagc aaaagaatat gtcaaacatg atgcatatac actaaaagtg attgcagaat
      901 cttctgaaga acttaaagca aaatatggtg aggactttga gggaatcaga aagatttact
      961 agtaggagga aatttttatg attcggaata ttttgctggc actaattgtc gcaatcaatc
     1021 tatattttat tatttacttt ctaagagacc ttttcaaaaa caaacaaaat ttcaaagaag
     1081 aaccagggga tatgcgtctg ttgcccttca cgtcatttat caccttcttt ctttcaacat
     1141 ttggcgtttc cgactttgct atcggaaccg tcctttatcc aaagttgaaa tgggtcagca
     1201 tgaaaaaact acccggaacg ttgaataccc aatgtgtcgt accggtagcc gtcatggcat
     1261 tgtcttatat cactgccatc aacgtagggg tcaagacact agctgtttgt attatctgcc
     1321 aaattatcgg tgcatattta ggaccaagat ttgtcgtgaa attaccagaa aaaacgatca
     1381 aactatttgt cggcatagga ttggtcattg ctgcattctt aatttttatg ggacaaatga
     1441 attggattcc ctcaaacgga acagccagtg aattgtatgg cggaaaatta atcttggcag
     1501 gatttttact ctttgtctat ggcgcattga acaatattgg cattggttct tatgcgctaa
     1561 cgatggtaac tgtctacttg ctaggcttga atccagttgc agcctttcct attatgatgg
     1621 gggcttgtac attctcagta ccgatcggca gtgtccaatt cattaaattt gatgaataca
     1681 gcagaaaaat cacacttttc acttcaacct tcggtgtatt aggggtattg gtcgctgtat
     1741 tcctagtcaa atctttagat acctatgtct tgaaatggat cgtaattttg gtcttactat
     1801 acagtgcata cacaatgttg ggcagtcaat taaaaaaagt ttcagcagct aattaaggag
     1861 cgattcaaat gttatttctt aaaaaagaag atattatcaa aagtttctca atgagagaag
     1921 ccatcgatgc agacaaaaaa gcattgtcat tgtattcagc aggaaaggca agtgtgcctc
     1981 ttcgcaccaa tatcgatgtg ccaaaaagca acggacaaag cttatatatg ccagcttatg
     2041 tagaaggtgg cgaaggtgcg ttaggtgtca aaatcgtttc cgtgtatcct gaaaacctca
     2101 agaaaaactt accaagtgta ccagccacga tgatcgtcct tgatccagaa acgggtatgg
     2161 tatccgcttg tttggatggt acctatttga cacaattaag aaccggcgct gttcaaggtg
     2221 cagcaacaga acttcttgca agagaagatg ctaaaatcgg cgcactgatc ggaaccggcg
     2281 gacaagcaca gtcgcaatta gaagcgatgt tgaccgttcg taaattagaa gaagttcgga
     2341 tttttgatat tgattttgac cgtgccagcc gatttgctga agaaatgatg caacagtttt
     2401 ctgtaacgat gcgcccaaca aaaaccagtc aagaatgcgt tgaaggagca gatatcatta
     2461 caagtgtgac cacttcaaaa cgtgcgacat tctctgctga gtgggtcaaa aaaggtgcgc
     2521 acatcaacgg agtcggtgct tacacaccgg aaatgtgtga aattccacga gaaataatca
     2581 aagccgcaga tgttgttatt tttgatacca tggacggtgt tctaaaagaa gctggggact
     2641 tcatttcacc gctgcaagat gggtatattc aaagagacag ttatcatggg gaactaggcc
     2701 aactgatcaa tgaagaattg atcggtcgga caagtggaga acaaatcaca attttcaaaa
     2761 cagttggttc ggctgtatta gatgtggtag ttgcgacaga aatcgttaat aaagctaaag
     2821 aaaataattt gggaaaattg atttattaaa taaaaagacc ggaagtaaac ctttaattag
     2881 tacatttata aaaagagaac aaaaaagact gtaatcaaaa tgcgattaca gctttttttt
     2941 gttttatttg ggaggagata gatcgtgttt atgactgtat cggatcattt aaaggtactt
     3001 ggttttatcc ctttatctag tagagggaag tatcaattgt atttgttaga tttaccaccc
     3061 tagcttttca ctggtgattg aaggaacata cgataaaaaa agtggtaagt atttttatga
     3121 tttttattct atgaaacttg atcctaaaac aaagaaaagt acgcagcacc ggatttattg
     3181 tacgcatgtt cctgtaaaag taatgtatcg tcgtgtgaga aattatttat acttcttacg
     3241 taaaaaacag caatcaagga acagaaaaaa tgcataatga ggaatatcaa gtgaaatttt
     3301 tatcagtttt gctctgtggt attgtgtatt gtcattagtt caatgagtat taacagggag
     3361 gaaaaagcaa atgaattttt ttcaaaatgt gtttaccgat tttgttgggg attttaagta
     3421 tttgattatg ttggcgatgc ttggtggtgc ggcatatatt gcctttgaac ggaaagcaag
     3481 caaagccatt ccattgattc ttgtgctagc agtagctgtt tggttagttg gagatacgtc
     3541 tggcgtattc aattggattt tggatcgtat gcggtcatgg gggcgataaa atgagtgaaa
     3601 tacgcaattg gacaaagatt tggtatatag agcgagtgtt ttataaattg tgggatgggg
     3661 tcgcgttacc tcgtcctgta acacaaacat ttgcgatatg gtttgggatt ggcttttttg
     3721 gggggatttt tcgaattttt ccatttgtta tggaacatac gattactcga caattttttt
     3781 gtccgtggtt atttgctttt ttaatgacac gaaaacaatt tcaaggaagg aagccttata
     3841 attatttggc ttcttttctt ttatttcagt gtcgttcaaa agaatccttt catggccaat
     3901 gggtaaagcc aatagaaaaa aaagaaatca aacgaggaat tcgttgtgta gtacgttatg
     3961 gaggtgaaaa ggatgcgact accaaaacta gtgcctaaga ttccttttta ttatttagaa
     4021 gacaatttag tttttggaga agaagatcgt gtgtacgctt attatgaatt cccaatgtat
     4081 tcatatagct tcgtgggaga agatcaggcg tatcaactcc aacaagcaat catgcgtctg
     4141 attcgtcaaa gtcattcttc gcatgttcgg ttcttttttt gtacaaacga agaaaaaatt
     4201 gaaaaaacga ttaaatcctc aaaagaattg gtgcgttcta aaggggaatt aaaaacgatt
     4261 gcctaccaac atttagaagg tgttcagcac attttagaag agctacatgg aaaatatatt
     4321 caaaatgttt gctggtatgt tgggattgag ctggtattag aagaaattgc tcccaaagaa
     4381 gctcattggt taaaagaatt tcgtattgcc gcaaaagatt tttttcaccg atccaatgcc
     4441 cgtttgtttg gagactttga aaccatccca aatgaaaaaa ttcaacgata taagcgattg
     4501 gagaatttat tgtataaccg gattagtaaa tactttcggt tacgaaaaac aacaccagaa
     4561 gacatggtgt ttttagtgga acatttagaa ggaaaaaaag aacaatcctt agatgaagtg
     4621 atgtatcgac caaatagctt taaagaagaa acgaatacgt atacgtatca ctatgatgta
     4681 ttgaatttgg ccagtgcagg aatcacagaa aagaaaaatt atctaatttt agaacaaggg
     4741 acagaaaaag aatatatcac gtatttatct ctttcacgta tgacccgtga tttggtattt
     4801 ccatttcaat cagagattta ttatttttta caatcggaat tggattttcc aatcgattct
     4861 tggttagatg tgaatctttt agataatcgt ttggccttgg cgaaagtacg tggcaaaaag
     4921 agtgatttat ctgatattta tgaaagtggt atgtcggttg gaaaagatgt aggaaacaat
     4981 gtacgcgaag cttaccaatc agccaatgag ttggaacaaa aattagaaga tacgcgagaa
     5041 gatttgtatg tattatcact aaacgttcgc gtgtcaggga agacctatga tgaaatgtta
     5101 aaacgtgtga gtgatgttcg caattttttt gatgtctatt ctatgtattt agaagtaccg
     5161 tgcaatgtac agctgctttt acattttgga agttatccag caggaaggcg agtgattgag
     5221 gattatcgtc aatatgtagg cgcagaattt attgctagtc ttggcattgg tgcgacacaa
     5281 caactaggag atggctgtgg tattccgatt ggatttaatg cagaaacagg aatcccagtg
     5341 tttattaaac catggttagc ggcacaagga ataaaaggaa cggttaccaa tactcttgcc
     5401 aaagcattaa ttggttcgct aggtggtggg aaatcattaa ctgagaatct cttgttattt
     5461 tggtcggtgt tgtttggcgc cttggctttt tgtatcgatc caaaatcgga acgttcaaat
     5521 tggtccgaag atttgccata ttttgccccc tacttaaaaa cagttaatat taccagtgag
     5581 aaagaaaata ttggtttact tgatccattt caattgatga gaagaaaaaa agatcaagaa
     5641 agtttagcat tggatgtgct cacctatatc acgggtgtaa gtattcggga cgaagaccgg
     5701 tttcctttgt tacaacgggc agttaaaact gtttctgatt ttgagggaac aaaaggatta
     5761 cttctagtaa ttcaggaatt atatgcacaa gaagcagcga ccgcacaacg cctggcaaag
     5821 catattgaaa gcttcaaaga actatctatt gcaggcctat tatttggaga tggcacgaac
     5881 caacaagggt taaatttgga tgccaaatgt aatctcgcac tggttcagga tttaacgtta
     5941 ccagatagtg aaactgtacc tgaggactat aactcttctg aaattttaag tattgcgatt
     6001 atgatgagtt tggctacgta tgcgctagat tttattaaac aaaatcgaaa aatttataaa
     6061 gcggttggct tagatgaaag ttgggcgtgg ttgaatgttg cgcaaggaaa aattttagga
     6121 gataaattgg ttcgtgaagg aagatctcgc aatgcaggga ttgatttttc aacacaaaac
     6181 acagatgatt taggtgatga aaagatgaga agtaaaattg ggttgaaatt catttttcgt
     6241 tcgaatgatc gcgaagaaat taccaaagca ttaagctttt gtggaatatc tgtcacagaa
     6301 gaaaatatcc agcgtgtaaa aaatctagaa aacggtgaat gtctgttttg tgacatccat
     6361 ggtaatattg gcattttgta tgtgtattat tggtttgaag atttattcca tgcatttgat
     6421 acacgaccgc caatggaaga aacctacgaa gaggaagaat ataaagacga gatattagaa
     6481 aaactggttg aagaaattga ggtgaattag atgaaacagt ggtattcaaa ggtttcattt
     6541 ttaattactc gccggaaact ggttttcata agtctagtca taatgatggg tgtttttttc
     6601 tttcacccat cattagtaga agcagctggt tggataaaag aaaccctagg cggcaaaaat
     6661 gccgtatatg attttgaaac atatccttta gataattata atttagattt ttttgtggat
     6721 acgtcgtgga attggttgcc gtggaaatgg ggtgaaggaa tttctaatac agttatttat
     6781 gggatatttg ccgttaccaa tattttatgg atgttaaatg tctacctgtg ttacttttta
     6841 gggtttcttg tccaagaagc ctttgaatta gattttcttt cagagttgat tggttcgtta
     6901 agtcatacaa ttcagaatat tgctggaatg aaccgtacag ggacattgag tcatggatta
     6961 gtccctttct ttggtggatt gttaattact ttagcaggtt gttcagtagt ttatcaagga
     7021 atagtgaaac aacaccctac gcaagctatt caacaagcgg tgacattttt gtttactttt
     7081 atttgttgcg gcgttttctt tatgaataca aacacatatt tagagaaagc taatggggta
     7141 caaaaagaaa tcaatagtga aatgttaacc attgccaaaa atctgttacc tgaacaaaaa
     7201 gaaaaaccag atgcaattaa ggccattcgt gagaatttat ttgccattca aattaagcaa
     7261 ccctggctag tgatgcaatt tggggatagt gatataaaaa cggttggtga agaacgtata
     7321 atcaatttat taaaagaatc accttatgat gaaggagaac agcgaaataa gcttgttgaa
     7381 gaagaagtaa ccaaacaaaa aaatggccat ctttcggtac aaaaagtgta tttgcgtttt
     7441 ggtatggtat ttttaacgct catcgtcaac attgtcatta gtatgagtgt tttggtatta
     7501 atcgttatct taattgcgtc gcaagtatta ttcttgttat ttataggatt cttacctgta
     7561 gcgatgattt tctcgttatt tccaaattca ggatcgttat taggtaatgc cttacagaaa
     7621 gtctttcaat tattgtttac aaaaatgggt attttactca ttttaaccat tactttttct
     7681 attagtcatg agttaaacca cttatccaag gacaaaggaa tgatttggac cagtttctta
     7741 caggtgacgt tatggttatc tgtctcgaca cgtgtcaatg aattattagg ttggatgaaa
     7801 attggtggcg tacaaacacg agctggggat cgaactggac gtttcttacg tggcatgatg
     7861 ttaggtacaa tgggtcaaaa aatgatacga ggaattggtg aaaattttgt tgggggtact
     7921 gccggaggtg tagctggcca aatgatttcc aaatctatga gtggtcaacg aagtatagct
     7981 tctacacctc ttatagagcg agtaggaaaa aaagtttcag ctatgacaga attaccggca
     8041 acgattgaaa gtagggcaga acaatggaag cggacaattc agtatgtccc aaccaatgcc
     8101 caatacaaag cacaaaaaat gaaatacgat tatttctctg ggcgaatgaa tgagtcggaa
     8161 cgacaaacac gagcgcgtaa ccttgcgaat gagcgacaga agaattttta tgaagcacga
     8221 aaagatgcat tgcaattaga gcaacaagag agaaaacaac gagcgatgcg ttcaatggcg
     8281 catcaaacag gaaaaacaca agtgacttct ggtaaattac aaacacggaa aagtgcaatg
     8341 attggtcgaa cagaacaatt tcctacgata gaaaaaagaa gtaacatttc aaatatagct
     8401 aaaaataaga aattgtcgaa gcaggaacat ccgattcatg aacgaagtac gaatcgaaag
     8461 attgaaactc cggttcgttg gacttcgact tctcgtcaaa acgcgagaaa aggtagaact
     8521 aaaaaagaat aaggaggagg gctatgtttc ctcggaagaa aaaactgtct attctctctg
     8581 aacaagaaac aagactaaaa ggaaagaaag acaagaaaaa agaaagctat aagggagcgc
     8641 gaaaaaggcg cttccttttt tttgtaggct ggagcttttt ggtttttagt gtttgttttg
     8701 gagtttataa taatttaact tctcaagata cgcatacaat ccatgaaaca aaagtcattg
     8761 ataaacaatt aaaagatatg actggaatag aaagttatgt gaaaaatttt gcatttttgt
     8821 attttacagt gagtcttgaa agcgaccaac aaataaatcg atcaaaagca gtagaaagtt
     8881 atttagctga tgggctgcaa atggataatg aaatagataa agacatagaa acgaatgtaa
     8941 aagttaaaaa tgtctcgatt tgggcaatag aggaacatga atcaaaaaaa catacatttg
     9001 tggttatgtt tcatgtctta ttagagatag aaaaagaatt caaagagcgt gtgtataagg
     9061 tggaggtata tcgaaacgaa ttatcatatg ccatagtgaa attgcctatt gtagcgagta
     9121 atgttaaaaa agcaacgatt aaagtagaca ctcggttcga aacaacgagc atttctcgaa
     9181 aagaacagga agaattagag aaattcttat ataccttctt tcgtatttat cctaaagcaa
     9241 acgcagaaga attaaaatat tatgggacaa ctcttttacc aattcaacag cctttagcct
     9301 ttgaagaact atcgaatttg caagtcgcaa aaaaagaggg tagatatgag attcattgta
     9361 atattttgta tcaagatcaa gaaacgcacc tttggtttac catgtactat gaaatgtcta
     9421 tgaaacaatt agagaatggg aactttcgaa ttgaggcgat tcattagtga aaaagatttt
     9481 tttatttagt ggcatctgta tgatgagttg tctgttttta ttatttgcga taattagcat
     9541 gtctagtggt gaatcgaagc acatggattc agcagttggt gttactcata cgggagaata
     9601 tatcgaaacc ttacctattt tttcagagat caaagggcgt ggtccgataa cagatgaaca
     9661 tgcccaagca gcagttggtg cagctgtaaa gtatcagtta ttaccgagtg tgattctttc
     9721 tcaattagga tatgaatcag cttatgggca gtcacaatct ggaagaaacg atacgaactt
     9781 ttttgggatt acgtggtttc ctggttgtcc ctatccacaa ggttctgcac gtgggattgg
     9841 tggttctgaa ggtggtttct atatgaagtt tccgaacctg aatgcttgtt atgactatta
     9901 tggatttatg gtggcgagtc aaagcaactt taatcaatgt gtgggcaata aagatcctgg
     9961 aagttgttta ttgattctag gtcgtggagg ttatgcggcg gcaggtatca ccgaaggcag
    10021 ttcgtattat caaggcgcaa taagtatcat aaagtcctat aacttaacgg aatatgatgc
    10081 ctttgcgatc aagcattgga atagcctacc aatcaaaaaa acttcgctta ttgcaggaaa
    10141 aagtaaaggc aatgcgaagg ttttggatcg gatcattgga cgacccgtaa ataatgggga
    10201 atgttatggt ggtacggcat ggtatgtatc tcaactaggt ggcccacagt taatgggttc
    10261 tggacacatg tttgcgatgt taatagggga agattataac tgggcaacct atggttggca
    10321 agtgatcatg aatccaaagc ccagtgactt acaagcagga gatgtggtca attggcaagc
    10381 aggtggtgca ttgtctcctg gaatctatgg ccacacgggt atcataacag atgtctcaaa
    10441 tagtggacaa agtttctcca ccgtagaaca gaacgccgag caggggcgaa ttatggcacg
    10501 gtatcaacgc ggctataacc aagcgaaaat tcgaagtctg gttcggaaag tgaaataaaa
    10561 gaattctttc gatgaaaatt tttagtagaa aagggagaag gatcgattgt gaaaaagtat
    10621 tattttttct ttctaagttg tttttgtttg tttggactta ctagttgtgg gtggattttt
    10681 tctgaagaaa aaacagaagt ttccttaata tcaaaagaaa agatgataca agcagaaagt
    10741 tcaagtaaag aaagcaaaag aaatcaggaa gacaaaacag aatgcaatat ttctgaagaa
    10801 atccaatatt tgttaaagaa ttttggaaga aaatgggtga attacacgga tatatacgaa
    10861 cgaaatcaat ctgtaaaaaa ctatttaacc gatcgttgta taaaagaaaa tgggattgac
    10921 aacgatccac atatacaata taaaacaatt ggccgtattc atactatcac acaagatgta
    10981 atccaatcgg atcaatattt attatttgga gaagaaacaa caaatgagat aactcggttt
    11041 gtgttacttc aaatcaaggt ggatcaagaa gtgcagaaga ttgataaaat caagatttat
    11101 tatgtaagaa gtgcatatta aaataaaaaa ggaattgtgg aaattgtttg taattaaatc
    11161 gaacagtgat tatttatttt aaattgaaaa cagagatagg atgaatactt attctatctc
    11221 tgttttcttt tggactaatc tagatatttt ttcgttttaa atttaattta atacccactg
    11281 caatagaagc taataaaata actaatccag ctaaaactcc tgatgattct ttttcaccag
    11341 tttggggaag agtattattt gactttgaat tagtatttga aacattcttc tctgatatta
    11401 aaattttaga gttagtgttt tttaaagaca ctggtttatc aggctcaggg ttctcaggcg
    11461 ttactggagt ttc
//
LOCUS       DAKCAA010000074        11330 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000074 DAKCAA010000000
VERSION     DAKCAA010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.075"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="OUE31_002302"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="OUE31_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HCU0223277.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="OUE31_002303"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="OUE31_002303"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HCU0223278.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="OUE31_002304"
     CDS             complement(2169..2906)
                     /locus_tag="OUE31_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCU0223279.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="OUE31_002305"
     CDS             complement(2997..3524)
                     /locus_tag="OUE31_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223280.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="OUE31_002306"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="OUE31_002306"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HCU0223281.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="OUE31_002307"
     CDS             complement(4401..4886)
                     /locus_tag="OUE31_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HCU0223282.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="OUE31_002308"
     CDS             complement(5039..5236)
                     /locus_tag="OUE31_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223283.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="OUE31_002309"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="OUE31_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HCU0223284.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="OUE31_002310"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="OUE31_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HCU0223285.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="OUE31_002311"
     CDS             9211..9423
                     /locus_tag="OUE31_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HCU0223286.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="OUE31_002312"
     CDS             9425..11104
                     /locus_tag="OUE31_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCU0223287.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3289 a         2444 c         1988 g         3609 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaatacggct ctttgtcaat aaggactgat
    11281 gagttgtgca aaatcaaatc tgagtcagaa tgaaccacat tctggctcag
//
LOCUS       DAKCAA010000075        11217 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000075 DAKCAA010000000
VERSION     DAKCAA010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.076"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            5..2377
                     /locus_tag="OUE31_002313"
     CDS             5..2377
                     /locus_tag="OUE31_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223288.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="OUE31_002314"
     CDS             2438..3898
                     /locus_tag="OUE31_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HCU0223289.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /locus_tag="OUE31_002315"
     CDS             3909..6113
                     /locus_tag="OUE31_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HCU0223290.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            6129..6278
                     /locus_tag="OUE31_002316"
     CDS             6129..6278
                     /locus_tag="OUE31_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223291.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6354..6947
                     /locus_tag="OUE31_002317"
     CDS             6354..6947
                     /locus_tag="OUE31_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HCU0223292.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6960..7859
                     /locus_tag="OUE31_002318"
     CDS             6960..7859
                     /locus_tag="OUE31_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HCU0223293.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7862..8347
                     /gene="ssb"
                     /locus_tag="OUE31_002319"
     CDS             7862..8347
                     /gene="ssb"
                     /locus_tag="OUE31_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCU0223294.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(8488..8691)
                     /locus_tag="OUE31_002320"
     CDS             complement(8488..8691)
                     /locus_tag="OUE31_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HCU0223295.1"
                     /translation="MIKTVKFVTVAIRLKVRWCVCAYFQNLTERRSLLPVETALGLMI
                     SFGSLIATIIFGILAVVNNNQKK"
     gene            8766..9026
                     /locus_tag="OUE31_002321"
     CDS             8766..9026
                     /locus_tag="OUE31_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223296.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            9463..9669
                     /locus_tag="OUE31_002322"
     CDS             9463..9669
                     /locus_tag="OUE31_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HCU0223297.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
     gene            9669..9920
                     /locus_tag="OUE31_002323"
     CDS             9669..9920
                     /locus_tag="OUE31_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223298.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            9935..10372
                     /locus_tag="OUE31_002324"
     CDS             9935..10372
                     /locus_tag="OUE31_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223299.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
     gene            10365..11072
                     /locus_tag="OUE31_002325"
     CDS             10365..11072
                     /locus_tag="OUE31_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223300.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
BASE COUNT         4237 a         1891 c         2339 g         2750 t
ORIGIN      
        1 ggacatggca gaagaaaaag aaccactaga caatagtcgc ttgggaaaat ccaaaagaaa
       61 attagtacga ttgcaaaatg aattaaacga acaaattgag aagatgtttg aacaccagag
      121 aaagaccaac ggtcagccaa tgaacgataa gagaaatggg cattcttggt ttaggcaaca
      181 agaacgttta gaaaacaaag tgcatagtct gagagaagag atcaagcaac aagaaaaaca
      241 ggtagaaaaa cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 cctggatatg acaatcgaaa atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg actttttcag ccgctacgat ccgaaaatac caacggaaat tggaaacatt
      421 agaacagctg aaagaaagat cagaaaaagg aaaagaaaat cttcttcctg aagtacaagc
      481 aattattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 agactatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctgc
      661 gccaactgat tctttgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tagaattgat
      781 cgatcaactc aaaacgttgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaagaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccca tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 aaaggaacaa aaacaaacgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaagcaaga
     1081 agtcaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtgaaa gaacttttga attttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ctgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaagga ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actacacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgggg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cttcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 ggcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctgtagaaac ggcagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtga ttttaaaagg
     2221 aaaaagttat ggaaaagaga ttcaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg aaacagtgtc agaagtggcc aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg cgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg tttgaaaatg accgaaaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagact atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ctctaagcaa caatttaaag cagccacaga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtagaa aatcttcatt ttgagacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaac atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaat gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagttaaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctaaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtttcga tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagttga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaagtcattt atgaagaagt cgcaaaagaa gaaaagatca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaat tggtttccgc
     3541 tcacaaagta aatgcgtctt ttggtcagca gctttctgtt aacgattcaa tagaagctat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagcttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg ctcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggatt ggaatgatca attgaagcat gaaatctacc aacaagagat
     3841 cagaaagcaa aaacgtgcca tgttgtttca acaaggtaga cagcaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaaaccgtc acaagcgaag gcttatgccg
     3961 atagcttttc taaagctacc cgaaaagatg ggtattttga gatccaagat cgattgtttt
     4021 caggagaaac tgtgatcacg tatggttttg gtcatttagt cgagttagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagagcattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatagctt
     4261 ggacgatcat tcaacaagca ggcgccgatc atggaaagat atttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagat gcagaagaga
     4381 cctacccaaa atttgaagaa gcacaagcac gccagatcgc cgattggttg atcggcatga
     4441 acggtagccc gctgtatagt ttactcttgc agcaaaaagg cataccagga agtttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attacaggaa aagattagaa
     4561 acttccaaaa agaaccatat tttgaaggaa aagcccaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggtac gatccaccaa gttgaaaccg
     4741 agaaaaaaag tgcggcaagt ccacgtcttt tttctctatc cagccttcaa tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagata ctttggaagc catgcaaggg ttgtatgaag
     4861 ggaaatatct aagctaccca cgaacagata ccccttatat tacagaaggg gagtatgcgt
     4921 atctgttgga tcacttagac gaatacaaac actttttaaa ggccgaagcc attcctactc
     4981 ctattcatac accgaatagt cgatatgtga ataataagaa agtccaggaa cattacgcga
     5041 tcattcctac aaagacggtc atgacggcag cggcttttga acaattaagt ccactgcagc
     5101 aggctattta tgaacaagtg ttaaaaacaa cggtggccat gtttgcggaa aagtatacct
     5161 atgaagaaac aacgatcttg acgcaagttc agcagcttca gctaaagaca gtcggaaaag
     5221 taccagtaga tctaggttgg aaaaagctgt ttggcaaaga gagcgacaga aaagaaaagg
     5281 aagaagaacc gctacttcct aaagtgacaa aaggagaagc ggtgacggta gatctacaag
     5341 tccttgaaaa agaaacgaag ccaccacaac cttataccga aggtacgttg atcacagcga
     5401 tgaaaacagc tggaaaaacc gtggatagcg aagaagcaca atccatattg aaagaagtag
     5461 aaggaatcgg tacagaagca acacgagcaa atattattga aactttgaaa caaaaggaat
     5521 atatcaaggt agaaaaaaat aagcttgtgg tgacaaataa agggatttta ctttgccaag
     5581 ccgtggaaaa agagccgctg ctaacaagtg ccgaaatgac cgccaaatgg gaaagttact
     5641 tattaaagat tggtgagcag aaaggaacac aagctacttt cttagctaat atccaaaaat
     5701 ttgtctctca cttgttggaa gtcgtaccgg gacaaatcca gtcaacagat tttggatcaa
     5761 cgttacaaga ggtgaaagca gccagtgaaa aacaggaagc aacgcgtcat ttaggtgttt
     5821 gtccaaaatg tcgggaacaa gaagtcttgc tttatcaaaa tgtggcggca tgtacgtctg
     5881 aagcctgtga ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gccacacaac
     5941 tgaaagagat cattcaaaac ggccgaacaa gccaatcagt cagaggacta aaaggtcaga
     6001 aaggttcgtt tgaagcaacg atcgttttaa aagaagactt tacaacaggc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac tataagaaaa gaacacgccg cactacaaaa taatgaaggg
     6121 gttatcctat gcgaaataca acacacaaac aacaagaaat cgaaaatcaa aaagcaaaaa
     6181 ttcgtttaga acaagagaaa ttacgtgcaa ataaaagaag actgcaacaa ttaaagaacc
     6241 agcagcgcat tcaaaaagaa atcgaattag atcgatagac gttaatcttg ttacaaataa
     6301 actactatga tatatttgat gtagtgtatt tgtaacgaag ggaggggaag taaatgcaag
     6361 ataaactgaa agaattgttg gctattcgcg atggaaattt atctatgaag gaagccagga
     6421 aatttggaat cgcagcaacc actgtacaaa gattggtgaa tcaaggaaaa ttgatcaaag
     6481 ttgatcgtgg ttattatgta gaggatggtc atggaataga tgatttattt tggcttcagc
     6541 aacgattttc caggggaatc ttctctcatg aaacgacttt agatatttac cagctttcta
     6601 cgaatatgcc gaaattcatt cacttaactt ttccccatgg ctataacgtt gatcgttcaa
     6661 ttacaaaaga gcagcagtta caatttcatt tcgtgaagaa agaagtttat gaactaggaa
     6721 aagtagaggg aacttccttt caaggaaatc ctattactat gtatgataaa gagcgtacac
     6781 tttgtgatat ttggaatccg agatatgaat ttgaatatga aatgaaatta gaagcattaa
     6841 aagagtacat ggaagaccca ttgagagatc caagtaaatt aagagattac atgacaaaac
     6901 tacatgtaga aaaagaaatg aaataccaca tgcaaagctt atattgatgg aggaaaaaga
     6961 tgacaccgac acaatttgca gcaaaaacaa gaaatttagc aaagagtaca ggattaaatg
     7021 cacagttagt gcaacggcat tttatgatgg atcgtctaat tgaacaaatt tctgaatcaa
     7081 agtacaaaaa tgacttcatt ttgaaaggcg gctttttatt aggatcaaaa tatggaatcg
     7141 atagaaggac aacaattgat atcgatacga catttagaaa tagcaaatta actgaagaaa
     7201 aattgaagag catttttaat gatttaacta gaaaacccac aaaagaaggc attgttttct
     7261 ctattcaagg aatgaaggaa acaagagaag ccgattttta tcctggattt caaattaaat
     7321 tggtggctaa tttagagaaa gtacgtgtac cgtttaaaat ggacgtgaca acaggagatt
     7381 ctatttatcc tgaagtagat acacactatc accaattaat gtttgaagat aaaaaagtgg
     7441 agattccagc ttatccaaca gaacaaatta ttgcagaaaa gctaagtgct acgttcagct
     7501 ttggcacaga taattcgaga gcaaaagatt actacgactt atttaccatt ccgaaactag
     7561 aaaatatcga tacgaaagag ttatacaaaa gtgttcgaaa tacatttaca aaacgtgggg
     7621 atacaaaacc gttgtccttt tattatgaaa gagaaatgga taagatcaga ggaaatgact
     7681 atttggaaaa gcagtgggaa aaatatcgct cagttaacac gtttgcgaat tccatttcat
     7741 ttacagatac agtcaacgaa attgatcacc taatgaaaag tgtgatcaaa attgaaaatc
     7801 aagaaagaaa acggcagttt aaaagatcac aacaaatgaa tcaagaaatg gagagataaa
     7861 gatgatcaat aatgtaactt tagtaggacg cttaaccaaa gatccagatt tacgttatac
     7921 cgcgagtggt actgcagtag cgacttttac cctagctgtc aaccgaaatt tcacgaatca
     7981 aaacggcaat cgagaagctg attttattaa ctgtgtgatt tggcgcaaac cagcagaaac
     8041 gatggcgaca ttagctaaaa agggcagttt gatcggcgtt gttggacgga ttcaaacccg
     8101 aacctacgat aaccaacaag gacaacgtgt gtatgtgaca gaagttgtgg ccgataattt
     8161 ccaactatta gaaagtaaag cagcgacaga aagccgtgcg cacgctgatc aatcgtccag
     8221 cagtccaagc cctaccacct ttgaacaacg ggatgtagct acgcctaaca acaatggatt
     8281 gaacgcttca caaaatccat ttggcggaca atcaatcgat attagtgatg atgatttacc
     8341 attctgattg taaaagatca ataaagttgt tataatggat acgaaaagag gagttgcgct
     8401 aacaactccc ctaacagcac cgtttaagac ggtgaccagc ttaatattat ttttgaaaaa
     8461 taatcgtcga ccggctaaag ctgacggtta ttttttttga ttgttgttta caactgctaa
     8521 gattccaaaa atgattgttg cgatcaaaga accgaaacta atcattaatc ctagcgccgt
     8581 ttcaacaggc aaaaggcttc tcctttctgt aagattttgg aagtacgcac atacgcacca
     8641 cctcactttc aatcggatag ccaccgtcac aaactttact gtcttgatca ttatagcata
     8701 tctaaaatcg aataaaaatt ctcaatttta gctgtttttg ctataatttt agcgaggtga
     8761 tcgtgatgaa caaatatgtt ggtttgcttg ataaaatccg agtaataaaa acacaaccat
     8821 tattggttcg ctttacttta caaacaattc atgaatcgat taattgtgta gttgcagata
     8881 ttgaaattat cgataaattg ttaattatgg atgatggaaa atacaatatt gccgtcacag
     8941 gtcatttcaa taaacggaat caattagtca ttgaatcgat gcaaattaga aaccccgatc
     9001 attttacgcg atcgatgggc atataaaaga agagctgcag tcctaaatga ggattgcagc
     9061 tctttttgtt ttacatagaa acaggaaaag acctttttag gaagacacaa gtgccttctc
     9121 aattgaaaaa cctttctctc actccaaccg ccaccgccgt tcgagaagaa aggaagtgaa
     9181 cgttgcacgt tcactaagat atggtgtctt gcaaagcaag acaaaataga aaaaacttcc
     9241 tctcaccaaa aggttcgttc ctgttcgcta tctctttatt gatttgccag accggcaaca
     9301 agttgccttt tatcaccaaa aagcgacaag gacaagggta aatggcacgc tgcgcgccct
     9361 tgtccttgtc gcttttcgtt gattcattct ggccaacaaa tcaataaaga aagaactaac
     9421 gaaaggaaat aaaacctttc ctaagaggag gcagaatcaa tcatgcgaaa gaaatttgat
     9481 tattggggtg ttcccttcag cgaattattc ccaaactatc atgcaccaca tactgtcgaa
     9541 tgcgattgtg gagaaagagc gaaatgtatc aaaagctatc gtttgtatca atgtccaaca
     9601 tgcgggaaaa aatatacctt gtcttatggc gattatgttt tgattgatga gaaagtaaag
     9661 aaacggtgat gaaaacacaa cacaaattat tgactgtaaa agaagtcgtt caaattttgg
     9721 tggacaaaga agtcatttct gaaaaagtag cagaagcttt acttattccg cggtactgga
     9781 cgatagaaac ccctttagta gaggatgcac cgactatgct atttgaagac ctagtgaaga
     9841 ttgcaggata tgaactgcat tatcaagaaa acatggaaac ttatgaaatc gaatattggt
     9901 taaccaaatt agagaactaa aaaggagaaa aaatatggct caaaattact atgacgaatt
     9961 tgtcaaatta cctttggata aaatggcaca aaaaatggag gatatgacgt tcctatacca
    10021 tgaaacacgt gtacccaaaa aacattacaa ggaaaaattg tcagtcgcag tggaagaaat
    10081 gattgaatca ggtgtcgaaa tgaatctcat tgcgacgtac tatcgaacac tggaagaact
    10141 gaaaaaacaa aatggaaaat ggtttttcca agccttacta tgcttggaag taggtgtcaa
    10201 accaagcact atcaaacctt ccgaatatca agccttagaa ctgacttatg caaaattcgc
    10261 acagattaag aaagctaaag caatggctag cgactggcta gatacttttg aaaatatcga
    10321 aaaaaatggt gcattttata cgattgaatc ggaggagaaa gataatgaat aaggtggttt
    10381 atcagctaac aacagaagat gtttcgcaat ttttaacaaa caaagaacac ttgaatgaag
    10441 taatcagacg gattcaaaaa gactttagtt gtatggaaga aatgaagtac tttattcaaa
    10501 gagtggaaga acagttgtat atggaaagtg aaacgagtca aacgaaggtt acagtcagcc
    10561 ataatcgttt agacgtgtat aaacgtcgtc ctgacacatt aaaaaaagga gcggagcttc
    10621 tacgactaga aacagaaaaa tatatcatga atgtttacct agaaaggagt gagctggtcg
    10681 aaaactttgt cagctacacg atttgcagga aacactatta ctcagaatca gaatattatt
    10741 caatttttga gagcatggaa ttaatggaag aagaaatgga agagctaaac agcaaagatg
    10801 cgacggtaga cgattattac cttgtattta ctagattttt gacgtgtggg acggaatcta
    10861 tcgtgttaat gggaatggat tatgaactca ctgtacccga agcatttttg agggaatatg
    10921 tagaagaagt agataaccca ggcgacgact ggtacacgac tttaactgat tttttagaca
    10981 cctacactta cgacgataca gaagaaatcc aaaatgaact tgaccgtaaa cgaatgccat
    11041 atcaacgatt tgaaaggaaa aaaggtcaat aaccatttat accgaaaagt gaggatgtgt
    11101 gaaataagaa caaaaaacct tgaaattaag ggaatggttc ttatttcgca ccaatcgatc
    11161 caaccgcccc cgccgcttag gtggtgcgaa ataagcgggc aaagcccgat aacctaa
//
LOCUS       DAKCAA010000076        11150 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000076 DAKCAA010000000
VERSION     DAKCAA010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.077"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            6..305
                     /locus_tag="OUE31_002326"
     CDS             6..305
                     /locus_tag="OUE31_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCU0223301.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="OUE31_002327"
     CDS             378..1739
                     /locus_tag="OUE31_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCU0223302.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="OUE31_002328"
     CDS             1761..2021
                     /locus_tag="OUE31_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223303.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="OUE31_002329"
     CDS             2035..2787
                     /locus_tag="OUE31_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HCU0223304.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="OUE31_002330"
     CDS             complement(2881..3486)
                     /locus_tag="OUE31_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCU0223305.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="OUE31_002331"
     CDS             complement(3542..4516)
                     /locus_tag="OUE31_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HCU0223306.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5613)
                     /locus_tag="OUE31_002332"
     CDS             complement(4894..5613)
                     /locus_tag="OUE31_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCU0223307.1"
                     /translation="MPKYEEIANILRERIRSKEYPPDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="OUE31_002333"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="OUE31_002333"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCU0223308.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="OUE31_002334"
     CDS             7164..8561
                     /locus_tag="OUE31_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCU0223309.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="OUE31_002335"
     CDS             8642..9082
                     /locus_tag="OUE31_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCU0223310.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="OUE31_002336"
     CDS             9229..9555
                     /locus_tag="OUE31_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCU0223311.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="OUE31_002337"
     CDS             9556..10305
                     /locus_tag="OUE31_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223312.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="OUE31_002338"
     CDS             complement(10331..10741)
                     /locus_tag="OUE31_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCU0223313.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         3538 a         1948 c         2291 g         3373 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagtttcgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atccatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaattaa
//
LOCUS       DAKCAA010000077        10844 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000077 DAKCAA010000000
VERSION     DAKCAA010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10844
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.078"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(135..1715)
                     /locus_tag="OUE31_002339"
     CDS             complement(135..1715)
                     /locus_tag="OUE31_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HCU0223314.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2116..3492)
                     /locus_tag="OUE31_002340"
     CDS             complement(2116..3492)
                     /locus_tag="OUE31_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCU0223315.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3620..4738)
                     /locus_tag="OUE31_002341"
     CDS             complement(3620..4738)
                     /locus_tag="OUE31_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCU0223316.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            4880..5314
                     /locus_tag="OUE31_002342"
     CDS             4880..5314
                     /locus_tag="OUE31_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0223317.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5392..5925)
                     /locus_tag="OUE31_002343"
     CDS             complement(5392..5925)
                     /locus_tag="OUE31_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HCU0223318.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6019..7197)
                     /gene="mutY"
                     /locus_tag="OUE31_002344"
     CDS             complement(6019..7197)
                     /gene="mutY"
                     /locus_tag="OUE31_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HCU0223319.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7190..7987)
                     /gene="recX"
                     /locus_tag="OUE31_002345"
     CDS             complement(7190..7987)
                     /gene="recX"
                     /locus_tag="OUE31_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HCU0223320.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8094..9476
                     /gene="rlmD"
                     /locus_tag="OUE31_002346"
     CDS             8094..9476
                     /gene="rlmD"
                     /locus_tag="OUE31_002346"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCU0223321.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9650..10228)
                     /locus_tag="OUE31_002347"
     CDS             complement(9650..10228)
                     /locus_tag="OUE31_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HCU0223322.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10550..>10844
                     /locus_tag="OUE31_002348"
     CDS             10550..>10844
                     /locus_tag="OUE31_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HCU0223323.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGEYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFF"
BASE COUNT         3230 a         2186 c         1874 g         3554 t
ORIGIN      
        1 acatttctat gattttaata tagtaaaaag agccgtcacg gaaaatccgt cacggctcta
       61 aacaaaatat gagaggctgt ttttgtttgg ctattcttat tacttgatgc agggcagctt
      121 gtgtcaagac ttctttacat caaacttttt aattttacat tgggatattt atccgcaaac
      181 cagcgttctg caaattggtt ctcgaataag aacaacggtt ggtcgaaacg gtcacgagcc
      241 aagatattgc gacttgaact catcttctca tccaaatctt ctggatcgat ccagcgagcg
      301 attttgtgtc ccattggaga catgattact tcggcgttat actcatttaa catacgatat
      361 tggaatactt cgaattgtag ctgaccaaca gctccaatga tatattcttc cgttagatat
      421 gttttataaa gctgaatcgc tccttcttga actaattgat agattccttt gtggaaggat
      481 ttttgtttca tgacattttt tgcagtcact ttcataaaca gctctggagt aaatgaaggg
      541 agttcttcat aagcaacttt tagttttcct tcgaacaatg tatccccaat ctgataattg
      601 cctgtatcat atacaccgat gatatcgcct gctactgctt tttcgacgtt ttctctcgaa
      661 tctgccataa attgtgtgac attgcttaat ttcagttttt tatttgtacg ttccaaccag
      721 acatccattc ctcgttcgaa tgttccagaa cagattcgga caaaagcgat tcggtcacga
      781 tgggctggat tcatatttgc ttggatcttg aatacgaaac ctgaaaattc ttcctcataa
      841 ggacttacca tctgatcatc ttgtgttttg tgtccataag gagctggtgc caattcaacg
      901 aaagtctcta aaaaagtctg tacaccgaag ttagtcaatg cagaaccaaa aaatactggt
      961 gtctgatcgc cacgagcaat tttttcttga ttaaatgcat ctccagcctc tttgattagt
     1021 tctacttctt ctaagacttg ttcatataag gaattttcag ttagaggatg attttcggga
     1081 agcagtccat cttcatccaa ttctactaat cgttcatcct gataattttc cggacgataa
     1141 aactctacac gattatggta gatatcataa agaccttcta gccctttacc cataccgatt
     1201 ggccaattca tcggataaga ttcgatatct aatagctctt ctaattcttc taacaattcc
     1261 aatggttcac gaccatcacg atctagtttg ttgataaaag taaatatcgg gatgccacgt
     1321 ttttttacaa cttggaataa tttctttgtc tgtgcttcga tcccttttgc actatcgatt
     1381 accatgaccg cactatccac ggccatcaaa gtacgataag tatcttcaga aaaatcttca
     1441 tgtcctggtg tatccaagat atttactcgt ttcccttgat aatcaaactg cataacagaa
     1501 ctagtaacag aaatcccacg ttgtttctcg atttccatcc agtctgattt ggcaaaatta
     1561 cctgtttttt tgccttttac ggtcccggct tgacggatag ccccaccaaa caatagtaat
     1621 tgttctgtaa tcgttgtttt cccagcatcc ggatgggaaa tgatcgcaaa agttctgcga
     1681 ttgtccactt gttgctttaa ttttggatta ttcataacct aactccattt cttccattca
     1741 attatttata ttttctctag gcacagattg tccgatctct taaagaaaga caatttcata
     1801 tagggctgtg acaaaagccg tgtagcagtc tctttttccg agtaaacggc gttctagaga
     1861 cagcctatca gcaataagcc cacccaagcc aaaaatacga aaagctgttt ttgcttggct
     1921 gctcttatta cttaatgcag gatagctttt tcacaacctt tgtcaactac tacaactgaa
     1981 tcagtatagc atggattcag cgaatgaaaa agccaccaaa ccataagagt caaatatttt
     2041 tttgtcagct gactaaaaga aaagacgtgt tgcttgttta ttcaagcaac acgtctttca
     2101 taaccaagtt tccaattatc ttcttggctc gtcatcttcg aattcttttc tgaagtatct
     2161 tcgttcttct tcaggttccg cttctgtttc ttccggatca tgaaaaatga cacggatttt
     2221 aaggattcga gaaccttcca tttcttcaga aaccagcgta atattatcga catcaaacga
     2281 taacttttcg ccttcatccg gaatcatgcc taatgctgta atcaaataac cagccatcgt
     2341 atctacatca ctcatatgca gatcactgtc aaaagcttca ttgaactcat caatcagcat
     2401 acgtccttgg atgatatatt cgtgttcatc gattttttca taaagattct caacttcatc
     2461 tgattcatca tcgatttctc cgacgatttc ttctaaaagg tcttctagtg ttgctaaccc
     2521 aacgacgccg ccatattcat ctaataaaat agccatctga ttctgcgtct ttttcatttc
     2581 atataacaga tcatcaataa agaccgtttc aggaacgaat aaaggctcct gcatgatttt
     2641 cttgatatct aaattatcaa agccgaattt atgggcagct tttagtaaat tctttgtatg
     2701 aaggattccg actactttat ctttgtcttc gttataaaca gggattcttg aatagttttc
     2761 ggataaaact tcattcacat tttcttccac agtgtcgttg atatcaatca taaatgcatc
     2821 cgttcgtggg accatgactt ctcgggcaac tttcgtatca agagaaaaaa ccccttggag
     2881 catttctaat tcttcattat tcaatacgcc ttcgttttca agcatataac gcatttcatc
     2941 tctggtcatt tttgaatctt catcatcaaa agtcatcggc gtgatacgcg ccaataaact
     3001 tgtggaagca gaaagcagcc agacgaaggg cttagctact acaccaatca agcgtatcag
     3061 ccctgaagtg aactttgcga cttcttctga tttatttaaa gcaatacgtt tagggtacaa
     3121 ttctccaaaa acaatcgata cataggtcaa aatagccagc acaatgatat ttgcaatatt
     3181 ttttgccgct gtgccgccac ctaataccgg agctaaccgt tccgataaag tattagctag
     3241 tgaagcacca gacaaaatgt tgaccaaagt gattcctact tggattgtcg ataggaaatt
     3301 atttggattc tgcaatattt ttaaaagctt ttgagatttc acatctcctt catcagcttt
     3361 ttgctcgatt cgattcttat tgatcgaaac aacagcaatt tcggaagctg ctaaaaaagc
     3421 attgatcaat gtcaaaacga tcaataataa aatctgcgct aacagcgact gactctcagg
     3481 gtcagcattc ataatcgcat tctctcctta taaaattaat ttttagttta cgatagaaaa
     3541 aaacgtggca ctatagccac gttaaaatgg tatcacaaag caattttctt tgcaataaaa
     3601 acaagtgtac taaaactacc tacgaggtcg tagcaatttt cttcttgttt tcattttgct
     3661 tgtcttcttt gacgattttg attatatagg aaatgatcgt cttgcagatt gcgtaaaaag
     3721 gaacacctaa gaagatacca agcaatccgg caatatttcc agctactaga agaacgataa
     3781 tgatcgttaa tggatggatt ttcagtgatt tcccaattac attaggataa atgatattcc
     3841 catccaactg ttggacgatt agcacaacca cacaacaaag taatgctttt accggatcat
     3901 tgaagactgt tactagaaat gcaggtgcta gtcctagata aggtcctaaa tatggaatta
     3961 ggtttgtcaa tcccgcaatg accccaaata agaaagcata atccacacca attaccatat
     4021 atcctaaaaa tgtgaaggta ccaacgaata aacattcgat tgcttgtccg ctaatgtaat
     4081 tagccaatgt tttattcagt tgccccaata actccacaat ttggtttctt cttttttctg
     4141 ggaaaaactg ttggatgttt ggcactagtt tttctccgtc tttcaacata tagaacaaga
     4201 tgaatggtgc tgtaatgatt actacggttg ccgaagcgat cgttccaacg atcgaaccta
     4261 aactattgga tactccacta aggaattgct gaatgattgt cccgtaagaa atgtctaatt
     4321 gctcaaaata tttattgata tctacttcct tgaacaaagg caattcggct acctctttta
     4381 accagctttc tacctgtttg atgaaatcag gcatattaga tgccaatgag gaaatttgct
     4441 gtactagact tgggatgaca ctaagtaaaa tccaaataat tgctgcaact aaaaggagca
     4501 gcacaattgc gacagcccat attcttttga tttttgcttt catcaacagc ttgacaatag
     4561 gattcaataa atagtaaaga aagcctgcaa tcagtacagg tgcaaataac gtggaaaaaa
     4621 atgtcccgat cggttcgaaa ataaagttta tttctgatga aatcatgatc aatgcagcta
     4681 tgatcaataa ttcaagcgac caaaacatta gtttagactg tctaagtttt tcaaacaata
     4741 gatttcctcc tttctttctt actagtatat attatattcg ttaaaaattc ttttattctt
     4801 tttttatttt tgaaaacttg ccatactttt tatttgtttt attttccagt atactatacg
     4861 aaaggaaggt ggctagacca tgaaagttgt acaaacaaaa gatacaatga gcaatattta
     4921 cttagatgct gtacggatca ggcatcaagt ttttgtagtc gaacagggtg tgcctttgtc
     4981 tcgagaaata gacaaagatg aagcccattg tatccacttc gtcctgtact cagataaaaa
     5041 agaaccgcaa ggaactgtac gtcttttgcc tttagaaaac ggaaaaatga aattacagcg
     5101 gatggcgatt ctttctgaat acagacacca agggttagga aaaatattga ttgaagaagc
     5161 agaaaacttt gctaagaatc aaggctataa tacgatttta ttaggggcac agtccacagc
     5221 tgaaactttt tacgaaaaac taggatatac agcttacggc gatccttttg aagatgctgg
     5281 catgcctcat atttatatga aaaagacttt ataaaaattt atttcgaaaa aagcaaaaaa
     5341 cagcaagctt ttgagaaaaa tctctcactg gcttactgtt cttttttgtg tttacttacg
     5401 cgacaattgc ttgtaacggt tataccaaat atcaatatag ccttccgaga acgggccatc
     5461 tccattattg atccagtcaa ccagaatctt cacattttct tttaggatga agtcaatatc
     5521 gttcgggtaa ttcatcattt tgctgtgcat ctcatattca tcgacatcca atagtcgttt
     5581 ctcgccgtca ggaaatacct tgatatccaa gtcatagtcg atatatttca aggcctcatc
     5641 gtccagcaaa aaaggtgaag ctagattaca ataataggaa accccctttt ctctgatcat
     5701 tgctattaca ttgaaccagt attttttatg aaaataaaca atcgctggtt cgcgcgttac
     5761 ccatcggcgt ccatcagatt cagtgactaa tgtgtgatca ttcacgccga tcatagagtg
     5821 ttcgcttgtt tttaatacca tggtatctcg ccacgttcga tgcaatttgc cgtcgtgctt
     5881 gtaactttgg atcgtcacaa actctccttc ttttggaact cccatagcaa cccttcctta
     5941 agcagcattt tgtgctttgt gtttgggtgt tcattacacc gacatcataa ttattatatc
     6001 aataaaaatg agctttgcct agaaaggatt cctattgttt cgatttttct ctaactgatc
     6061 taccagtttc atttggacct taggaaaaac gaccgaatca aatgcatcag gcttcaacca
     6121 cttcgaagtt ttgttctcgg taaattcttg ttctgctccc tcggttgccc gtccgtaaaa
     6181 aaggagaaca tgccatttca gatgactaaa aatatgagta acttctccta aatgtcgtgt
     6241 ctgccaaaca aagagttcct gcttttcaaa tgggagattt tgctcttctt ctgctactag
     6301 gtcatcaaac agatcgattt ctggctttgt ttcccattct tttttcaatc gctcatactc
     6361 ctcttgtgtc acttccatca ttggaaatgt ccacatattc gccagcaatt tttggctatc
     6421 tctttcttca aaataatacg ctccagaatg attttgaaga gctgcactga tataataaac
     6481 gtcttttggc tttgcttttt ttgtttttac aggaaaactc gtttggattc ctcgtttgtt
     6541 agctaaacaa aaggcttgga tcggacaagt ctcacacttt ggagaagttg gtgtacagat
     6601 agctgaacct agatccatca ttgcttggtt gaattcacct ggatgctttt catcaatgat
     6661 tttccgcatc gcttcatcaa agattttcct gctagaagct tttgcgatgt ctgcttcaat
     6721 gcaaaacaat ctgctgacta ctcgcatcac gttgccgtca actgcaggtt ctggaagtcc
     6781 aaatgcgata cttgcaatcg cgcctgtcgt atatggtcct attcccttca atgagctaat
     6841 ttcttcaggc gtttgcggca tttccccatc aaattctgac atgatctgtt tagcagcagc
     6901 ttggatgttc cgggctcttg agtaataacc aaggccctcc catgctttta aaagcttttc
     6961 ttctggagca tttgctagct cttcaattgt aggaaaccat tccatgaaac gataaaaata
     7021 atcgatcact gtgtctactc tggtttgctg aagcatgatc tcagagatcc agatacgata
     7081 aggatcacga ttatagcgcc aaggcaggtt tcttttttct tgttcatacc attgaatgaa
     7141 ctgatcttga aattcttttg tttctttatc tgtccatttt tcccattctt tattcacttt
     7201 cctcttcctt ttccgtaatg aatcgctgga tcatatccaa atcaaatcct ttttgatata
     7261 agctttgctt tacttttaga tttctttttt taggttcaaa ccttaaattt cttcgccata
     7321 gtttatctcc ttgtttgact aaataatcat attctatttc ttgatctgct tcttgcggaa
     7381 gatcagctat cgcttgttgg atcacttctt gagaaaagcc tttcgtcatc aatgtttgtt
     7441 ggatttttct caataattct ttttggcttt ttccgtgatt ttttccaaac gctttttcgg
     7501 ctgtctgatg tgcattttga acttggtctt caaatgtata ttggctgagc gcttgttcaa
     7561 tgatttcagg tttcaaacct ttttgctgca tctgctgcgc taatttcttt ggtcctttgt
     7621 cacttaagcg catattcgtg cgcacataac tttccccata gaccaaatca tcgacaaggt
     7681 ccaattcttt taagcgggct acgattttat ttcgatcttc ttgaaggatt tccttttctt
     7741 ttaagtatgt tcggatttct ttttccgatc gcaactgata acttaagtaa ttcattgcta
     7801 ggtgaaaacc gaaatcagct ccgctactct tcttgatctc ttggatagtt tcttcgtcta
     7861 attcccgtcc ttttaataat cgatagcgta ctaatacatc ttcagatact tgtaaagctt
     7921 ctccttcaga taaatctacg cgatagaaag ggcctttgcc tttactgatt ctcgtaacgg
     7981 ttaacataaa catcctcctc gaacatatat tctctatcat accacagaaa atccccgtaa
     8041 tcaggtatta tatgttagaa taaaccacag aaaaaagaaa aagggagata cttatggcag
     8101 aaacaattgt caaaactgga caaacggttc ctttgaaaat caagcgttta ggcataaatg
     8161 gtgaaggaat cggttatttc aaacggttga tcatatttgt tccatatgca ctaccaaaag
     8221 aagaagtact agtgaaaatc acgaaagcaa ctcctcgcta tgcagaagga gaattaataa
     8281 aagtcaaaaa aacaagcaaa gatcgcgtag tggcaccatg tcctgtttac tatgaatgcg
     8341 gtggctgtca attacaacac ttagcttatc aagctcaatt ggattttaaa aaggatctgc
     8401 ttttgcaagc attggaaaaa ttcaaaccag caggctttcg atcttatcaa cttttgccga
     8461 cgatcgggat ggatgagcct tggcattata gaaacaaagc acaatttcag ttacgaaaaa
     8521 ataagcagac tcaaaaaatt gaagctggtt tatacgaagc aaactctcat cagttagtcc
     8581 ctataacaga ctgcttggtt caagaacctc gaacacaaaa agtaatgaat actgttgttc
     8641 aactattgaa taaatttgat gcacccatct atgatgaacg gacaaacagt ggaatcttcc
     8701 gcacaatcat ggttagaatc ggtgttaaaa ctggggagtt acaagttgtt tttattactc
     8761 gcagtaaaaa attcccgcaa aaaaacgcaa tgatccgtga gatcaatgaa cgactgcccg
     8821 aagttgtttc aatcatgcaa aatgtccagg cacaaaaaac gtctctcgtg atgggggatg
     8881 aaacgatcca cttatgggga aaagaagcca ttgaagaaca aatcaatgaa gtgactttcg
     8941 atctttctcc tcgtgccttc tttcaactca atcctcagca gaccgaattg ctttatggcg
     9001 aaggaatcaa agcattagat gtccagccta atgaaacgat cgtggatgct tattgcggag
     9061 ttgggacgat cggcttaagt gtagcaaaac aagccaaaga agtacgggga atggataccg
     9121 ttcctcaagc aatcgctgat gcaaaaaaaa atgcggaaag attaggatat cacaacactc
     9181 gatatgaagt cgggacagca gagcaagttc tgcctaaatg gttgaatgaa ggttttcagc
     9241 ctgatggtat catcgtagat ccaccacgta cgggtttgga taacgcattg atccaatcat
     9301 tattgaaata ccctccaaaa aaacttgttt atatctcctg taatgtttct acacttgcca
     9361 gagatctggt taatttaagt aaaaagttca agattgaata tttacagtcc gtcgacatgt
     9421 ttcctcagac tgcacgttgt gaagttgtcg tgaagatgac gagactcgct gactaaatga
     9481 aagaggttgt gaaaaagtct gccctgtatc aagtaataag aacagccaaa caaaaatagc
     9541 tcttcatgtt ttatgaatac tgtacttgtg accgaagagt taacaggagg acactattta
     9601 tttaaaaaaa gggttgtgac atagtttttg tcacagccct ttttgattat tattggatat
     9661 tcacgtctat cacttgataa aatgcatttg tcgtatcgct gatattccat actgctaaaa
     9721 tcacattata tccttttcga tcctgcggaa gtgtgatcgt ttggttgact gtttttggtg
     9781 gaacagttgc tttgtcgtct atttttgtga tcaattcaaa atcactaaat ttcaaaggtt
     9841 gattaggatt ccaagttggt ttggtaatgt agtaatccca agtacttgtc cgatgttgtg
     9901 ctgttaaatt ccaagtaata tttaatgttc ctggattaac catgttttta tgccatctgt
     9961 tagatgtctg ttcatctaaa ggctcaaagc cgctgactcc tgcactagca atttttccat
    10021 caatgaatgt atttttggta gcttcgatac tttgcggttc ccattgtgct cttccgacat
    10081 tttgatttaa gtttcctgct gctgatgttc ctaggtatgc acggcttcct ggagaagtaa
    10141 tataaccatg cgcaaaacct ggaatgctaa aaccgaacaa ccctaaacta actaacccaa
    10201 taaacaataa cgtactaatc tttttcatgt agaaacctcc ttcatttgat aaccacattg
    10261 taaacgcttt attgtattaa cacaaacatt atgcttttat aattttatgt tgaagtaaaa
    10321 aaggtgaaaa aagtaagatg cagattataa cagaagtaga cgagaaaagt acaaatagaa
    10381 aacatgagaa tcaaatcata tgatcttttt caaaaacatc attcatataa acaaatgttc
    10441 aactttttaa taacaacaat tatcaatttt tttcttactt cacaaactaa atacaggtct
    10501 tgctgtgagc cttcatggta aactactatt atagaaagga gttagtaaaa tgaagatgat
    10561 aaaagatatt cgtttttggg tttgtgttat aggaattgtc atattaggct ttttatcagg
    10621 gttgcttagc ggaaatcccg gagaatatta ctattctttg caacttccac catttgcacc
    10681 acctagctgg atatttgggc cgatgtggac cttactgtat atattgatgg gtatttctct
    10741 ttatttgtta cttaatcaca acaacaaaaa acagcgaaac aatcttgtcg gtctttttgt
    10801 gattcagttc atttttaatt ttatatggtc tgctctattt ttta
//
LOCUS       DAKCAA010000078        10448 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000078 DAKCAA010000000
VERSION     DAKCAA010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.079"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..129)
                     /locus_tag="OUE31_002349"
     CDS             complement(<1..129)
                     /locus_tag="OUE31_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCU0223324.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDS"
     gene            402..2873
                     /locus_tag="OUE31_002350"
     CDS             402..2873
                     /locus_tag="OUE31_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCU0223325.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2976..4712)
                     /locus_tag="OUE31_002351"
     CDS             complement(2976..4712)
                     /locus_tag="OUE31_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HCU0223326.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4709..5413)
                     /locus_tag="OUE31_002352"
     CDS             complement(4709..5413)
                     /locus_tag="OUE31_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0223327.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5544..6047
                     /locus_tag="OUE31_002353"
     CDS             5544..6047
                     /locus_tag="OUE31_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HCU0223328.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6007..6345
                     /locus_tag="OUE31_002354"
     CDS             6007..6345
                     /locus_tag="OUE31_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HCU0223329.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6366..7784
                     /gene="ffh"
                     /locus_tag="OUE31_002355"
     CDS             6366..7784
                     /gene="ffh"
                     /locus_tag="OUE31_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HCU0223330.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7896..8474
                     /locus_tag="OUE31_002356"
     CDS             7896..8474
                     /locus_tag="OUE31_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HCU0223331.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8478..8999
                     /locus_tag="OUE31_002357"
     CDS             8478..8999
                     /locus_tag="OUE31_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCU0223332.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9078..9632)
                     /locus_tag="OUE31_002358"
     CDS             complement(9078..9632)
                     /locus_tag="OUE31_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCU0223333.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9885..10160
                     /gene="rpsP"
                     /locus_tag="OUE31_002359"
     CDS             9885..10160
                     /gene="rpsP"
                     /locus_tag="OUE31_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HCU0223334.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10172..10423
                     /locus_tag="OUE31_002360"
     CDS             10172..10423
                     /locus_tag="OUE31_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HCU0223335.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
BASE COUNT         3414 a         1920 c         2144 g         2970 t
ORIGIN      
        1 agagtcatcc aattttcctt taataaactg cgcttgaacg cctttatatt ctttttcaat
       61 cagccattct tcatcaaaaa ataaatgttt atctgttaat ccgagtaatt ttctagtatg
      121 attatccatt gagagactcc tttggtagga tgacgttttg gtcgactaaa ttttaccaaa
      181 agtgagtctc tttttgagtt gaaacgaaga aaaagtgtta gtagaaaatc gccttcgatt
      241 ttccaccaac acaaaatatt atagaaccct ttttttttgc tatatgacag gaatgaaagg
      301 tgtttgcaag cttaatgtga ggaacacttt ccatatctgt tctatactgg ataggagaag
      361 tttggaaata tccagaaaac gaaatcaatc gaggtagcca catgaagaat aaatggataa
      421 atcgaagtaa aaaaaagaaa gtaacacaaa gatcatcaga taaagtcatc cgtctttttc
      481 catcgtataa agaaggatta acggcagatc aagtcaagga acgaatagaa aaaggtgcag
      541 caaataattc agtcgatccc acattcaaaa caaatcagca aatcgtattg gaaaacatat
      601 ttacgtattt caatttgatc tttcttatct tagccatttt gctttgttta gtagaatcct
      661 ataagaactt gactttttta ccagttatca tagccaatac aggaatcgcc atttttcagg
      721 aaattcgatc caaaaagatc ttggacgaac taaatgtttt aaatacagca aaagtcaatg
      781 tcatacgaga cgggatagaa caaacaatag atatagaaga ccttgtaata gatgacattg
      841 ttattttaga gactggatat caaattccag cagatgcaga ggtcgtggaa gggaaactgc
      901 aagttaatga ggctttattg acaggcgaag cagatgaaat aaccaaagaa ataggtgatc
      961 cattaatgtc cggcagtttc attgtttccg gaaaagctta cgcccgatta gacaaagttg
     1021 gagcagattc gtatatttcc cagctgacag tcaaagccaa gacaatggga gaaggagaac
     1081 agtcggagat gattgcttct cttaatcaat tgatcaaatg gattgggatc atcattattc
     1141 ctatcggtat cctgcttttt tctcaaagtt acttttttaa tggaaacacg atcaaagaaa
     1201 gtgtcgttgc aatggaagca gcattgatcg gtatgatacc tgaaggactg tacttgctga
     1261 cgacgattgc attagcatta agtgcgacta aactagcaaa gcaaagagtt cttttacaca
     1321 atatgaaaag cattgagaca ttggcaaggg taaatgtcct ttgtgtagat aaaacaggaa
     1381 cgatcacaga aaataaaatg tctgttcaaa aaatgatcgt ctctaaaaaa caagaaataa
     1441 tcagtcagtc agatcaattg gaagcatgca ttgctgacta tgcaaaagcg atggcaggag
     1501 acaatgcaac aatggaagct gttaaagcat attttacaaa aaccactgat caatcctatc
     1561 accatgttat tcctttttct tctgtccaaa aattcagcag tgtagcgttg gcagacaagg
     1621 tgtatgtttt aggagcgccc gaaatggttt tgcgcgatca attgccggaa tatgcggaag
     1681 agtttgtttc tttcgctgaa aaaggctatc gcgtgttggt ctttggtgtg tacgatggga
     1741 ttcttgaaga accagtattg acagaagcag tcacaccatt aggctatatt ctgattgcta
     1801 atcctatcag aaaagaagca agagccacat ttgattactt caaaaaacag caagtagcca
     1861 tcaaagtgat ttctggagat aatccgctca ccgtatccaa tgtagctgtc caagcaggga
     1921 tttcacatgc tgatcagtac gttgatgcat ctaaattatc agaagaagaa tatgaagcag
     1981 ctgtcgaaaa atatacagtt tttggacgcg tcaagccaga acaaaagaaa atcttcgttc
     2041 aattgataaa gcgtaacaat acagtagcta tgacaggtga tggcgtgaat gatattctag
     2101 ccatgaaaga agcagactgc agtatagcga tggcttccgg aaatgaagcc gccatgcagg
     2161 cctcacaagt ggtcttactt gattctgact tttcacgcat gccagaagtt gttgcagaag
     2221 gacggcgcgt tgtgaacaat attgagcgat cagccagctt gtttttagtg aagaatattt
     2281 tctccttttt gctctcactg ttttcagtga tctttgctct gacctatcct ttagaaccat
     2341 cacaaatcac attgattagt ttgtttacta tcggacttcc atctttcttg cttgctctag
     2401 aagaaaacaa aaagcgaatc agagggaaat tcatcatgaa tgtgatggaa aaagctgtgc
     2461 caggtggact aacagatatg atcgtagtcg gtgcgttggt gatctgcggg gtgactttga
     2521 atctaaataa aacagatgtt tctacagcat ctaccatgct tttgattgca gtagggttcc
     2581 tcgttctcta taaaatctgt tcaccgctga ataaattcag aagtcagatc attcttttct
     2641 gtgctagcgg taactttttt tcggtcatct ttttgcataa gctgttttca atcaccggta
     2701 tctcagctgt atcacttttg ctgttgagca ttctattttt ctcggcagat tcgattttta
     2761 ggcatttgac cacattggta gaatatttgt ttgaacgtaa aaatgaaaaa gagcaaaagc
     2821 cgtttagtcg cgtagctaaa aaatttctat cgatatttaa acgagaaaat tgacgaaaag
     2881 tatctcaaaa aagagtaaaa aagaacaacc actcgtgtat ctttcgaagc aggatgagtc
     2941 atccaacttt aaaacgcacg agcagttgct cttttttaca ttttcggaat ggtaacggtg
     3001 aaagtcgaac ctgttccaag atgactgtct acagtaatcg taccattaag gagttgcacg
     3061 tagtctttta caatcgctaa ccctaatccg gtcccgcctg aatgtcggct tcgcgccttg
     3121 tctacgcggt aaaaacgctc aaagatccgt tcctgatcct caatgtcgat acctatacca
     3181 aagtcttgga cagaaaacga tagatcatct gttgcctgat agcggataat aatctcgctg
     3241 tcgctttttg aatattggac agcattttca atcagatttt tgataattgg ataaaggata
     3301 tctgttttag tagtaaatgg ttcgttcttt ccaatcaatc gaatcgtcaa ccgtttcttt
     3361 tcgatgattg gctgataatt ttgaacgatt tgctggaaat aaggttctgt ataaattgtc
     3421 tggatctcgt aagaattctc gccatctttt gacagctgga tgatttcccg aatcagttta
     3481 tctaaccgga tcgcatcttt ttgcatgatc tcaagaaaag aagtcagagt ttgcgggtca
     3541 tcttttgcac catccagtaa agtctcggta aaaccaatca gtgaagtcac aggagttttt
     3601 aattcgtgag agacgttgcc aacgaaatcc ttttgtagct tttctaaacg tcgcactttc
     3661 gttaagtcat acgccacccc tagaatctgt ccggtacctt ctgaattagt aaagtagcgc
     3721 aaactcaagt ctaatgtctg ccgaccttct gtaagggtga tctcctgatg gatcagcgga
     3781 tgctcaggag tcacttgatg aatcagctga atgagttttg gctcttgaat gacttctgtg
     3841 taccgctgtt caggttgata gcttaccacg tttaaatgta gctgcatctt tggattaagc
     3901 agtagtaaac gagaatcagc atcatcaatc aggaatacgc caatcatcag ttcgttcagt
     3961 aacgtatata attgctcttc tgtggtagta cacgcccgat acatcttact catttgttcg
     4021 ctcaacgcat taatcgtctg atacaattct tcccattgat cgggtgtttg catgattact
     4081 tccgcctgat taggattttg caccattttt tttagtacgg gcagcacggt tttcaatggc
     4141 tggttttttt gatagatcag ataatagatc attcctgcaa gaacaaggaa gaaagacaga
     4201 aagaagaaaa agacccaacg gcgaaaactc tcagttctcg gtaaaaaaac gcttgtcggt
     4261 tctgcgatac gtaaaatggc ttctaactgg ccactttttt tgactggtaa tgcgacatat
     4321 aaaagatcct cattcaaagt agtacttttg cgcaaagcgc tacctaggtt cccaccattc
     4381 aatacggctt tgatttcggg acgggagttt cgctgttcat tcaatgtttc attgtttgtg
     4441 tcaaataaga tctttccagt agcatccatt aaagtaatcc gttcgttcga ctgatggacg
     4501 aattcttcca aagcagtttt gttttgcgct gcttggaggt tttcgacatc taattgccgg
     4561 atcagcagtt gtgctttttt tgtcaggtag ctttcttgct gttccacgat ctgctgttga
     4621 aaataatggg aaatcaattg ccagccacca aaaaacaaac taactaaaag aataagaaag
     4681 aagagacgtt cataaatttt tttccatttc atcgtttggg ttcctgaaac ttatagccaa
     4741 atcctctaat agtcaccaag tactttgggt gttttggatc tcgctcgatt ttttctcgca
     4801 aatgactaac gtgtacatct acgattcggc tttgtcctgc gaagtcaaaa ttccaaatgc
     4861 ggtctagcaa tgtgtctcgg tcgatcacac ggtcttttcg tttcatgaaa taaacaagta
     4921 attcaaattc tttcggtgtt agttcaatca gatggtcgtc tacggtcact tgataattgg
     4981 tcaaatcagc agtgatttgt ccaatcgata gatattcagg ctcagcttca tcttttgatt
     5041 gcttacgagg ttcaattcgt ctgaatattg ctttcatacg ggctaatact tcgcgaggac
     5101 taaatggttt ggtcaaatag tcgtcagcac ctatttctag gccaatgatc cgatccactt
     5161 ggtcatcttt agccgtcagc atcaaaatcg gtgtttcatt tttttcttga cgcagccgct
     5221 gagtgatctc catgccatcc atcgttggaa gcatcacatc taaaatgatg aaatcaaatg
     5281 attgttctaa tgctaattct aatccttcgc ctccatctgt ggcactggtt accttgtagc
     5341 cttctttttc caaattgaac gtcaagagcg ttacaataga aggttcatca tcaacaacta
     5401 gtattttttt cattcaaatc tcctttaaat aggtttcatt ctgtttatat tttagcatag
     5461 aatcagtaca aagggctatt ttacaaaaga aataaatggt ataataggaa ggcactttgc
     5521 tgaatagaaa ggaagagcag tcaatgattg gaatcagtgc atgtttaggc ggtctggcct
     5581 gtcgctatga tggacagaaa aaagaagtac cagaattgat ggaactagtt gaaactggag
     5641 aagctgtcat ggtctgtcca gaagtgatcg gcggattacc aattcctaga gatcccgctg
     5701 aaatcattgg tggaaatgga ttcgatgtgt ggaaagatca agcaaaagta tggacgacaa
     5761 gcggcgaaga tgtaacggaa gcgtacaaaa atggcgcgat caaagcctat caaaaattgc
     5821 aggaaaaaca cattgatcta gtcatcatga aggaaaaaag cccttcatgc ggaacccatt
     5881 cgatttatga cggaagtttt tccggaataa aaaaaaatgg tgccggagtg gctactgctt
     5941 attttattca gcaaaaaatg actgtgctct ctgatgaaga atggctgaaa actagaggtg
     6001 agcagaatgg aaatcgaaaa gaccaatcga atgaacgcgc tctttgaatt ttattcgacc
     6061 ttattgacag aaaaacaaat gaactacatg gaattatatt atgcagatga tttttcatta
     6121 ggtgagatcg cggaagaata cgaagtaagc cgacaagcag tatatgacaa tatcaagcgg
     6181 acaagcaaga tcttggagga ttatgaaaaa aaactccatc ttttttctaa ttatattgtt
     6241 cgagaacagg tattggaaaa tatgactgca tatattacag ataagtaccc ggaagataaa
     6301 aaactacttg aatatgtaca gcaaattcaa gcaatcgaag aataaataaa aggaatgaag
     6361 aaaatatggc atttgaaagc ttaactgaac gtctccagca ggcgatggga aaaataagaa
     6421 aaaaaggaaa agtatcagaa gctgacgtaa aagaaatgat gcgggaaatc cgccttgcct
     6481 tactagaagc cgatgttaac ttgcaagtag tcaaagattt tactaagcgc gtacgcgaac
     6541 gtgcggtagg ggcagaagtg ctggaaagtt tatcacctgc acaacaaatc gtaaaaatcg
     6601 ttgatgaaga attgacgatc acacttggtt ctgaaacagc agagttaaat aaatcaccaa
     6661 aaataccaac tgttatcatg atggctggtc ttcaaggggc aggtaaaacg acctttactg
     6721 gtaaattagc caattattta aagaaaaatg aaaatgctcg tccgctccta atcgcagggg
     6781 acgtatatcg accagctgcg atcgaccaat tgaaagtatt aggtcaacag ctagacgttc
     6841 ctgtatttga tatgggaact gaagtcagcc cggtagagat cgtccgtcaa gggatggagt
     6901 tagcaaaaga aaagaaaaac gactatgtat tgatcgatac ggcaggacgt ctgcatatcg
     6961 atgaaacatt gatggatgag ttgaaacaaa tcaaagaatt gacgcaacca aatgagattt
     7021 tgcttgttgt cgatgccatg actggtcaag atgccgtcaa cgtagctgat agcttcaacc
     7081 agcaattagg tattacaggg gtcgtcatca ctaaacttga tggggatact cgaggcgggg
     7141 cagcactatc gatccgctca gtgacaggcg caccaatcaa attcatcggt tctggtgaaa
     7201 aattgactga cttagaagta ttccacccag atcgtatggc tagccgtatc cttggtatgg
     7261 gggatatgct gacattgatt gaaaaagcgc agcaagacta cgacgagaaa aaagcggaag
     7321 aacttgcaca gaaaatgcgg gaaaattcat tcgatttcaa tgactttatt gaacagcttg
     7381 atcaagtgat gggtatgggc ccactggaag atctaatcaa aatgatccca ggaatgaatc
     7441 aagtccctgg aatcgaaaac gtcaaggtag atccaaaaga tgttgaacgc aaaaaagcga
     7501 tggtttattc tatgacgcca gcagaaagag caaatcctga tctgttgaac ccaagccgtc
     7561 gtcgccgaat tgctgccggt tctggaaaca gtgttgttga agtgaatcga atgatcaaac
     7621 aattcaagga atcaagaaaa atgatgcagc aaatgtccaa aggggatatg aacatcccag
     7681 gtatggacca aatgtttggt tcaggcgtca aaggaaaact aggcaaaatg gcgatgaatc
     7741 gaatgatcaa gaaaaataag aagaaaaaga aaaaacggaa ataagatgaa aaaaacagct
     7801 tcggtacaga ctgaaaatgt ctactgccgg agcttttcta tcagcaattt ttattcttta
     7861 ctaatacaat tactctaaac gaagaggtgg cacagatgag atgtccgtgg agtgaacaaa
     7921 cagaaagtat gcggcaatat catgatactg tctggggtgt tcctgaatat gatgaccaaa
     7981 agctgttccg aaaattgatg cttgatatta atcaagccgg attgagctgg cagacgattt
     8041 taaataaaag tgaagcattc gatgaagcat atgatcgatt cgatatcaaa aaagtcgcaa
     8101 attatggaga aacaaaaatc agtgaactaa tggaaaacaa aggaattatt cgtaaccgaa
     8161 gaaaaatcga agcagccgtc caaaacgcca aagcagtctt gaaaattcaa gaagaaatcg
     8221 gcagtttttc agagtatctt tggtcgtttt ctaatggaaa aatcgttgat tcttcttatc
     8281 attcacaaga agaagtccca acaacaagtc ctctttcaga tgaattagca aaagatctaa
     8341 agaaaagagg atttaaattt atcggaagca caacaatcta tgctttttta gaagctgtcg
     8401 ggatcatcaa tgatcacctt gacagttgtt tccgcaaaga agaggtcgta cgtatcggca
     8461 gaaagggcga ataaagcatg cgaaaaatca tattttatgg tgctataagt ttagatggct
     8521 atttggcaac gaaaacggat gatcttcaat ggctttttga cactccaaca ggtaagcaaa
     8581 ctacttatga agctttttat gaaacaatcg atacgaccat catgggcaga aaaacttatc
     8641 aggaagcaaa aaaatatttg gagaccgaag caatttatcc agagaaaaag aatttcgttt
     8701 tttccaccca cgcacaatta caattgccag atgctgaggt cgtaaacgaa gatcctgttg
     8761 cttttctaaa aaatctacaa atgacagaag gaaaagatat ctgggttgtg ggtggcggtc
     8821 gattgatcaa accgctattg gaacatcaaa tgattgatga atggtatatc cagattaccc
     8881 ctgtattatt aggggacggg attcctttat tccaaaaagg aacatatgaa gcgcgttttg
     8941 aaatgctaga cacgacacga ttcggtgaat ttatcgaatt gcattatgta cgaaagtaga
     9001 agtaaataaa ataaaaaagg caactatatg cagaaatgtc ctgtacatag ttgccttttt
     9061 tattaccgtt atgcttttta ctctgttaat ttgttagaaa aatctagata cgcatctaaa
     9121 atcgtttgga agaaacttaa tgttccttca acgatattac cattttcatc aattagattc
     9181 gcaacgtttc cgatatatgc ttccggttgc tgcaaggttg gcacattcaa aaagacaagt
     9241 gattggcgta gatggtggtt tgcgccaaag ccgccgatcc cacctggtga tgcagtaacg
     9301 actaaacctg gtttatgatc ccaaacactg tgtccataag gtcttgagcc tacatctaaa
     9361 gcatttttca atactgctgg cacagaacgg ttgtattcag gagtaacgaa aacgacaccg
     9421 tctagtcccc tcacttcctc acgaaaacga gtccattcag caggagcctg ttctggagtt
     9481 tcgagatcct cattgtaaaa tggcagatca tcgattttta caaatacact ttcgtaccct
     9541 tcaggaagca atttcgcaaa agcttctgct acttttttgt tgtaagaatc ttttcttaaa
     9601 ctaccaataa aaaatccaat tttttttgtc atacgatttt tcctccttca aactatctat
     9661 aataatctta caaaagataa gtaactggag caaataaaaa cacttactga caaaagctac
     9721 atagaagata gattacttat ttttaacaaa aaagaagtct aaaatcttct attttctaaa
     9781 aaaaatcgaa tttaatcaag ctgtaaagaa aaaaagcttt acagggtaaa aaaaaactgt
     9841 tacactacat cttgtgaata aaacaatgga ggtggaaata aataatggca gttaaaatcc
     9901 gtttaaaacg tatgggttct aaaaagagtc cgttttaccg tatcgtcgta gctgattcac
     9961 gttctcctcg tgatggacgt ttcatcgaaa ctgtaggtac ttacaatcct ttgaaagacc
    10021 ctgcagaagt agttttaaaa gaagacttag ttcttgactg gttatcaaaa ggtgcacaac
    10081 cttctgacac tgtacgtaac atcctttcaa aagaaggcgt tatgcaaaaa caccacgaag
    10141 ctaaattctc aaagaaataa ggtgaccgga tatgaaagat ttaagcgact tagtcttaac
    10201 aatcgttcgt ccgctagtca cttatcctga tcaagtcaag ttagacgtcg tagagtcgaa
    10261 agacttttac gagtacaatc taacagtggc tcctgaagat attggccgta tcattggaaa
    10321 acaagggcgt gttgctaaag caatccgcac aatcgtttac ggtgttcgga tcaatgcacc
    10381 gaaaaaagtg cgtttgaata tcatcgatga taaggaaaag taaataaacg tgctgtactc
    10441 gaattttc
//
LOCUS       DAKCAA010000079        10411 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000079 DAKCAA010000000
VERSION     DAKCAA010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.080"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            111..851
                     /locus_tag="OUE31_002361"
     CDS             111..851
                     /locus_tag="OUE31_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223336.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(1142..1810)
                     /locus_tag="OUE31_002362"
     CDS             complement(1142..1810)
                     /locus_tag="OUE31_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCU0223337.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            1944..2231
                     /locus_tag="OUE31_002363"
     CDS             1944..2231
                     /locus_tag="OUE31_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223338.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            2647..4185
                     /locus_tag="OUE31_002364"
     CDS             2647..4185
                     /locus_tag="OUE31_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HCU0223339.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            4182..5147
                     /locus_tag="OUE31_002365"
     CDS             4182..5147
                     /locus_tag="OUE31_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0223340.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            5134..6456
                     /locus_tag="OUE31_002366"
     CDS             5134..6456
                     /locus_tag="OUE31_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCU0223341.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      6519..6623
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6697..7440
                     /locus_tag="OUE31_002367"
     CDS             6697..7440
                     /locus_tag="OUE31_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0223342.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            7455..8447
                     /locus_tag="OUE31_002368"
     CDS             7455..8447
                     /locus_tag="OUE31_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCU0223343.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            8459..9196
                     /locus_tag="OUE31_002369"
     CDS             8459..9196
                     /locus_tag="OUE31_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0223344.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            9186..9908
                     /locus_tag="OUE31_002370"
     CDS             9186..9908
                     /locus_tag="OUE31_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCU0223345.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(9992..>10411)
                     /locus_tag="OUE31_002371"
     CDS             complement(9992..>10411)
                     /locus_tag="OUE31_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HCU0223346.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3456 a         1792 c         2172 g         2991 t
ORIGIN      
        1 atttatgaaa ttcatcgcta ttttcttaaa ataatcagcg cattgctact gaaaacaatg
       61 aatctgtgct attattgaga aaagttccat ttttgagaag gatggtttga atgaaagaaa
      121 tcagacgaaa acatttccgt tttcctgcgt acgatgatga gttaggcgta aaattaacca
      181 acgacaagaa gcgagtatta tttgacggac aagaagatct tttgactgaa cagaatcagt
      241 ccccgtttga acagatgaaa gaatttcatt tcacgaacac gaacaccgag aaaatccgtc
      301 gcaagcgtcg tgcaacaaat ggattgaagt cagctccgcg taaggaaaat ttggaaaagc
      361 ataaaggaaa attaccggat tataccggcc attaccaatc agaaatcaca tcgacaggac
      421 gaaaaaaact ttttggtgat tcctctcgtt ctgtcagaca aagtgaaaca aggacagagt
      481 ccaagcatac tacacgaaac gcatctgttg acacgaaggt gcgggagcgt tcttattttg
      541 ttcctaaata tgtacccgca tcgattatcc cagaccctag agaaagcaaa atttctgagg
      601 atcatttaat cgaatcgatg aaaaaaacgg atgactctta tctgttgttc gatacagaac
      661 cgacgccgta tcaagaaaaa agaaatggtg agccgtctgt acgaacattc aatcgaacaa
      721 aaacgttaga ggaaacaaag cagtcagaag aaaaaaaatc gaaaaaaagc catggtatct
      781 tagaacgctc attacaagga ttgatcgatg atcaaggaaa ctctttggga gaaaatagct
      841 attttaaata agtgatatac aaatttatat tcggctacag ttggaaagga aacgctgcgg
      901 cgtttcctta ttttatactc tatccgaaag tttatatcgt atcctcaaat ttttttgagt
      961 ttaagcgaat tttttctccc aataagtaag aaaataatgg caaaataaaa aaacaaacta
     1021 ttttcgcaga tcgtttgcaa aaatagttta tttttttata aagaagattt tactgaataa
     1081 tatcatttta gtttacataa tgatatttct gtaaattaaa taaagtagtg aaaaataaga
     1141 atcagtgctc taactgttca agaggatcaa gtggttcaaa tgtttctgta gtctgttttg
     1201 cttccaattg gggcaaaaca gatccaattt ccagatactt cactttattc aatgtataag
     1261 atagaataga acagctaagt aatgtataca gaaaatgtgt gagatccaaa taaagcaagg
     1321 agacaactaa aataccaaaa gtaatcaaga aaagactttt gccaatctta atatgaaaat
     1381 atttttcaat ggcttgataa atgatatctg ttccgcctgt gcttccgccg aatcgaaaga
     1441 cgagaccgca accaatgcca gaaagaatac ctgtcatcaa actattgatc agtagactat
     1501 ctacagcaaa atgtatatga aggctctccc ataaatgtaa aaagaaaact agcgcaaatg
     1561 ttccgacgat cgtccggaga aaagcgtgtt ttccaaaaag aaacaatgag ataagcaata
     1621 aaggtaaatt aaaaagcagt gaagtgacag aaggagcgaa tccaaaaaga ttatgcaaaa
     1681 gcaaagcaat accagtaacc ccaccatctg ccagcttaga tggaatattg attcctgtca
     1741 cagctaatcc gtagattcct gcgcctaaaa tgattccgca caattctgta aataaattta
     1801 attttttcat ttctagcctc ttttcttttg aaaattttca gcaacttctt tattatactg
     1861 acttatactc ttacttcaag aggaaaatga aaaaaaatta tttttggctg tttcttttta
     1921 tttatcaaat aaggagtgga aaaatgcgag cagcagactt attgacaatt cttacaaaat
     1981 cacccaaaaa aacagagtat caaggagttt ttttggctca agaacaaaaa ctggtgcctg
     2041 tgacaatggt ccagataaat aaagcaaatc aatttatctt tttatttgaa cacggcaaag
     2101 caccacttgc tatgaaagac atctttcttt ttttgatgaa gaaccgtgag aaagctgttt
     2161 attatcagtc aaaagaagaa ctcattcctc tttatggagt gaaagagata gaaaataaag
     2221 tggtgatata agtaaaaata agaaaacaag acgtttatga tgtcaaaaca accatttttt
     2281 acatttttgg caaaaaagtg tcatgataca gtataatatt cgttgaacag gccaataaag
     2341 gtgttctccc ccacgagatt tctactttat tggctgtttc tttttattaa aataaaagtt
     2401 gtgtgtgtaa aaaagatata gctgattcca agtgacaatt tcgtatagat ttttatggta
     2461 ttcgtagtga aaaaacgaga accaaaaagt tgatccgact ttgttgcttg gattcttttt
     2521 ttgtcagcat atttagaggt atttttttct tttttttgtt cgtgctgtaa ggttaaggca
     2581 agacaagtta gttgggaaaa aggaaagaaa tgtttatact taaagaataa cagaaaggaa
     2641 ggtcgcatga ataattttat acaaacatta agtgaaagaa aaggcgagtt gctggaagct
     2701 gcatttcaac atctgtccat ttctctcatt tctttgctga ttgcagcact gattgctatt
     2761 cctttagcga tttgggcagc caatcataaa aaaatggcag aagtcttatt gcagatcacg
     2821 ggtgtgctcc aaacgattcc ttcacttgcc ttattaggtt tacttatccc atttgtaggg
     2881 atcggaactg ttccagcatt gattgcactt gttatttacg ctttgcttcc gattttccaa
     2941 aacacgtata ttggtctagc tgaaattgac ccgtctattg aagaagcagc ggtagcattt
     3001 ggtatgtcca gaatgagacg cttgctgaaa gtagagcttc ccatcgcatt acctgtcatt
     3061 atctcaggta tccgaactgc cttagtttta atcatcggta cggctacttt ggcagcattg
     3121 atcggagcag gtggattagg gacatttatt ttgttaggta ttgaccgaaa tacacctgtt
     3181 ttgacattga ttggtgcgat cagttctgcc ttgcttgcaa ttatattcag cggactgatt
     3241 cgctggttgc agcataagaa acctcgatat tccatcatta ctttagcagc agtggtgtgt
     3301 ttatttggcg gcgtttcttt atatcagtct gccttgttta aaaatgaaac catcacgatt
     3361 gctggaaaat taggagcgga acctgaaatc ctgatccaaa tgtataaaga attgattgaa
     3421 gacaacacaa aaacagaagt tgaattaaaa ccgaattttg gcaagacgag ttttttgttc
     3481 aatgcactgg atcaaggtca aatcgatatc tatcctgagt tcacaggtac tgtcctagaa
     3541 agcttggtga aggtacctga agcaatgaaa agtgctgatt tgacaaaaga aaaaacatat
     3601 gacgaagcag aagaattatt gaataagcaa ttcgatatga cattattaaa accaatggct
     3661 taccaaaata cgtatgcctt ggcagtcaag agatcttttg cgaacgaaca tcaacttaaa
     3721 aagatttccg atttggcagc tatctctgat cagatcaaag cgggattcac actggaattt
     3781 attgatcgtt cagatggata taaaggaatc caagaagcat atggcttgaa tttttcaagt
     3841 gtacaaagca tggagccaag tttgcgttac caagcaatca ataatggaga tgtcaatatt
     3901 gtggatgcct attccacaga tagccagctc aaggagtacg atctagtgac tctagaagat
     3961 gatcgagggt tattcccagc ttatcaaggc gcaccgctga tgaaaaaaga ttttgctaaa
     4021 gaacatcctg aaatcgttaa agcactgaat aaattaagcg gaaaaataac agaggatcaa
     4081 atgattgata tgaattacca agtcaatgtc gaaaagaaaa agccgacaga agtagcacga
     4141 atcttcctga aaaatgaagg attagtaaag gaggaagatc agtgactaaa ttaatcgagt
     4201 tcaaacatgt gcaaaaaaag tatgatggaa agtatgtcat cgatgaccta aatctggcaa
     4261 tcaaaaaagg agaaatcttt gttttggttg gtccttccgg tagtggaaaa acaactactt
     4321 tgaaaatgat caatggatta tctaaaccat cagcaggaga catctacttc aaaggaaaat
     4381 cgttaaatga atataatctg cagaaaatgc ggtggaatat gggatatgtg ctgcagcaaa
     4441 tcgctttgtt cccgaccatg acagtcaagc aaaatattga agtcatccct gaaatgttag
     4501 gttgggaaaa gcagaaaaga gcagaccgtg tagatgaact tcttcaaaaa gttggcttat
     4561 ctcctgatat ttatcgagat cgtatgccta gagagttgtc tggaggagaa cagcaacgga
     4621 tcgggatcat ccgagctatt gctgcaagcc cagatgtgat tttgatggac gagccattta
     4681 gcgcattaga tccgatttca agaaactcat tacaagaatt ggttttgtcc ttacacgaag
     4741 aattgggcac gaccatcgtt ttcgttacgc acaatatgga agaagcaatc aagctaggtg
     4801 atcgtattgc atttatgaag gatggagaaa ttatccaatg tgacacacca gagcagttat
     4861 tgatgaatcc taaaaacgac tacgttcggc atttctttga tgaaccgaaa cagacgaaag
     4921 agtggcgagt agaagattta gtcgtcaatg gatatttctt aaatgaaata ccagaaaatg
     4981 ctcgtcaaca agtttgcttt gatacgccta tgaaagaagt atattcgctt ctttcggtgt
     5041 atccaagcat tgtgatagta gaaaagcaaa gaagtattgg gtcgctgaca agtaaagaaa
     5101 tctttgcttt tttaagtcga gaggaggaag gaaatgaaaa catatgatgc aatcatcatc
     5161 ggttcaggtg tgagcggctt aagtgctgct tatggattga aagaagcagg taaaacagta
     5221 ctagtggtcg aagaagatct atggggcggg acttgtccta accgtggatg tgatcctaaa
     5281 aaagtcttgt taagtgcagt agaggcacgt aatcgggtaa aacaattgag tggaaaaggt
     5341 tttaacgaga tcccaactgc caactgggaa gaacttcaaa aattcaaacg aacatttacg
     5401 gatccagtcc cagaaagccg aaaaaaacaa ttagcagaag ctgaaatcga tcatctttca
     5461 ggaaccgctc gttttttgga tgattcatct attgaagtca acgaagaagt cttccatgcg
     5521 gattacttag ttttggcaac cgggcaaaga cctacgatct taccagtgga gggaaaggaa
     5581 tacttgaaaa ctagtgcaga ctttttatca ttgcctgtac tgcctaaaga aatcattttt
     5641 atcggtggtg gttatattgc ttttgagcta gctacgattg ccaatgctgc agggagcaaa
     5701 gtaaccattg tccatcataa tcaacggcca ttaaaagaat ttgaggcgtc tttggtagag
     5761 gaagccgtcc atcaaatgga agcatctggc attcagtttg cttttggtgt tgaaacccaa
     5821 aagatcattt cagaaggtac tcgctatcgt ttagtcggaa aagagacgga attagtagca
     5881 gatatgattt tttgtgcgac tgggagacag ccgaatacag aatctttagc acttgagcaa
     5941 gcgaatatcg tctttgataa acacggaatt gcagtcaatg attatctgca aacgagcaat
     6001 ccaaaaattt ttgcgtgtgg agatattgtt tcaaggaaaa ccccaaaatt gacaccagtc
     6061 gccacttttg aaggaaatta tgtagctaag cggataacgg atgcaacaag cgaacctatc
     6121 aaatatccga ttatacctac gatcgtctac gccagtccta aacttgctga agtaggagtt
     6181 acaaaaagtc acgcctcttc gtcagatcaa gtggtagaga tggatcttac cagttggttc
     6241 acctatcatc gtgtcaatga accagttgct aaggctgaat tgacctttga ccagcaaaat
     6301 tatttgattg gtgctgcagt gattagcgag caagcagacg aattgatcga tgatttgaca
     6361 ctcgtcatca atcaaaaatt gactaaaaaa gagttggata gctatatcat ggggtatccg
     6421 acattggcaa gtgatctctc ctatttattg aaataatcag catgataact aaagcgcttg
     6481 ttgctttttc cttcttgtgc tacactttaa aaaatgaata cctgtttctg gggatgtcgt
     6541 agacgacatg agagtaagtt gtgaacttag acccattgaa cctgtcagtt aatactggtg
     6601 aagggagaaa catagcagac gcttgaagcg ggttactatg tcgtgcccat ttcaagcgtt
     6661 ttttgttatt catattagaa gaaaggaggt aacaaaatga agaaaaatct ttatccagca
     6721 gtcagtatgg cattcatttt aattatttgg cagattgttg tcatagtttg gaaaatacct
     6781 gcctttattt tacccggacc tgctgctgta ttttctgcat tagcggcaga tgcacaagta
     6841 ttactttccc attctgtcac gacattaaat gaagcagtgc ttggtttggt aatagctagc
     6901 gttctttctt ttattactgc cttggcaatg gattattgga agtttttaga aatgtctttt
     6961 tatccgttac tagtgatttc acaaatgttg ccaatcatgg tgttagggcc attacttacc
     7021 ctatggtttg gtttcggtat gcttccaaaa gtgatccttg ttgtcttgat aagctatttt
     7081 ccgatcgtag tttctttttc ggatacattg aggaaagtat caaaagagca aatcatcttt
     7141 ttgaaaacga tgggggcaga tacagggaag atttatcgaa tatataaaat accagcgggt
     7201 ttatccggct tcttttccgg tttaaaagtg gctgctactt attgtgtcag cggagcagtc
     7261 gttggagaat ggctaagcgc tcaagcaggc ttagggtatt acatgatacg cgtaaaaaac
     7321 agctaccaga tcgataaagt ttttgctgcg atcatttgtg tcattctatt gagtttattg
     7381 ctgaatggcg cttgttcatt attgaaaaaa gggtattatc gtatgcttta tattttttaa
     7441 gagaagggga tcaaatgaaa aaattatggc ttttattacc gctactgttg cttttatccg
     7501 cttgtggcac tgcaaaagaa acaagtagca aacaagaaat aaaggatttg aaaaaagtga
     7561 cacttgtttt ggattatgta ccgaatacta atcatactgg catctaccta gcaaaagaaa
     7621 aaggctatta taaagaggct ggtttaaatg tccaaatcat cgaaccagga gataattcga
     7681 caagtattgg tctagtaggt gcggacaaag cacaatttgg tgtaagttat caagaagatg
     7741 tcacttatgc tcacgcagat ggacagaata taccagtcaa agcaattgct acagtgatca
     7801 aacataatac ttctggattc gccaccctat cagacagtaa catccattca ccaaaagatt
     7861 ttgaaggaaa aacatatgca ggttggcaaa gtccaagtga agaagctgtc ttaaaagctg
     7921 tgatggaaaa agacggcggg gacttttcaa aactgacaat ggtaggaagc aatggagaag
     7981 ggccagaaag cttaggaaaa tcctcagata tccaatggta ctttgaaggt tgggatatga
     8041 tcaaagcaaa agaagcgggt attgaactaa actatatccc attgaaagaa ttagatgaac
     8101 ggttagatta ctatactccg gtaattatta cgaatgatca actgatcaaa agtgatccag
     8161 aattggtaca gtcttttatg gatgccacga aaaaaggcta tcaggaagct attaaggatc
     8221 caaatgacag tgctaaactg ttgcaaaaat atgcaaaaga aaatgatcgg acgtttttag
     8281 aagaatcaca agcattcttg tcaaaaaatt atacggatga tcctgagaat tggggattga
     8341 tggaagaaaa agtttggcgc aattatacag cttttatgca ggaaaacgga ttgatcaagc
     8401 aagatgtacc ttcgcaagaa ctattcacta atcagtttat aaaataggag tgatagatat
     8461 gtcaatccaa atcagccact tgaatgtagt cattgaaaac ctgaaaatat tagaagacat
     8521 ccatttcact atccctaaag atacctttac atcgattgtc gcgccaagcg gagccggtaa
     8581 gtcaacattg ctgaaaactt taacaggagt ccagcctatg acttctggaa cgatcaaagt
     8641 agacgatcaa aaagtaactg gtctccatac agcatttagt tatatgccgc aagaagatat
     8701 gttacttcct tggctgagcg tctatcaaaa cgttacgtta tatcaaaaaa tcaatcatct
     8761 aacaatcaat gaagaacaag taagggatta tctggatatc tttgggttaa acggctatga
     8821 acattttttg ccggaacaat tatctggcgg gatgaagcag cgaacggcct tgttacgaac
     8881 aatcatgaat ccttcttctt acttgcttct tgatgaacca tttggagcgt tagatgctat
     8941 gaccagaggg cagatgcaag actggatgtt gaagctgcct aaaaaagcaa agcggactac
     9001 tttacttgtg acgcatgata tcgaagaagc aatttattta tcagacagga ttcttgtgct
     9061 ttccgcccgt ccggcacatg tgattgctga gattcaagtg cctgaaaaac gacggtcacg
     9121 tgaatggcta ctgcagcaat cagagttgaa gcaaacgatt tatcagttat tggcaggtga
     9181 attagatgtt aagtgatgct cattgtcatt tagatgggag tcagagttta gcactccttc
     9241 agcaggaaca cacgattttg acgatcatca attgtgattc gccagaagaa tggaaggaaa
     9301 acagacagct tgcagcaagt aagactcaag ccttaagtta cggtatccat ccttggaaag
     9361 cagatagcta tacgtttgaa caagttgagc cttttttgaa aaaagcaagg atcatcggtg
     9421 aaatagggtt agataatatt tggacgaatg taccgatgac tacacaaaaa aaagtatttg
     9481 agcgacagct tgcttttgca gccataaatg agaaacctgt tgtactgcac acaaaaggat
     9541 gcgaaaaaga gatcttaaat tatatccaag cttaccctaa tcactatttg atccattggt
     9601 attcttcttt ggactatcaa caagactata ttgatttagg ctgttatttc agcattggtc
     9661 ttgatttgaa aaagaatcca gcagtctggc aactagctaa agcagtccca atcgaccact
     9721 tacttattga aacggatgga ctacatgcag cagagtgggc tttagggggg attttttcag
     9781 aaaaagatta tgtctcactg cttgaagaac agttaaagac aatcgctgag atcaaagagc
     9841 tatcagttga agaagttaaa aaaaatactt atcaaaactt ggaacgtttc attagattag
     9901 gtaaataaaa aagagatgtg acacaactag tgtcgcacct ctttttggct ttctttgtat
     9961 aaaagtaaac tgtttgatta ataaatgaat cttagtacca accgtttgct tcccagaatg
    10021 ctttcgccgc ttcccaagaa ccataacgtg aagtaacata ttgttctgct actctttctt
    10081 ggtttgcagc agagtagtca ccatttaagt aagaagaatc taattggtaa cgtccgatgt
    10141 aacgtccgtt cgttgctgtg taagaaccgc ttgattcttt ttgtgcgatc cattcttttg
    10201 cagagcttgt gcttgctgga gtagcagcag tttctgttac agcaggagca ggttgtgttt
    10261 cagcaacagg cgctgcttgt ttttccgttt gaaccgtttc ttgtacaaca ggttgttcag
    10321 cttggactgg tgcttcttga acggctgctt gaggttcagc agctgcttgt gcagagcctt
    10381 ctgttgggat tgttaattgt tgtcctgagt a
//
LOCUS       DAKCAA010000080        10199 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000080 DAKCAA010000000
VERSION     DAKCAA010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.081"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(208..663)
                     /locus_tag="OUE31_002372"
     CDS             complement(208..663)
                     /locus_tag="OUE31_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HCU0223347.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(801..2729)
                     /locus_tag="OUE31_002373"
     CDS             complement(801..2729)
                     /locus_tag="OUE31_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCU0223348.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QCKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(2926..3759)
                     /locus_tag="OUE31_002374"
     CDS             complement(2926..3759)
                     /locus_tag="OUE31_002374"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCU0223349.1"
                     /translation="MFFANIIKAVILGIIEGITEWVPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(3951..4655)
                     /locus_tag="OUE31_002375"
     CDS             complement(3951..4655)
                     /locus_tag="OUE31_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCU0223350.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(4678..5304)
                     /locus_tag="OUE31_002376"
     CDS             complement(4678..5304)
                     /locus_tag="OUE31_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCU0223351.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            5630..8005
                     /locus_tag="OUE31_002377"
     CDS             5630..8005
                     /locus_tag="OUE31_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HCU0223352.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(8029..8520)
                     /locus_tag="OUE31_002378"
     CDS             complement(8029..8520)
                     /locus_tag="OUE31_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HCU0223353.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            8707..9627
                     /locus_tag="OUE31_002379"
     CDS             8707..9627
                     /locus_tag="OUE31_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCU0223354.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            9781..10125
                     /locus_tag="OUE31_002380"
     CDS             9781..10125
                     /locus_tag="OUE31_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HCU0223355.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
BASE COUNT         3320 a         1878 c         1940 g         3061 t
ORIGIN      
        1 caaaaagcag tatcaaacac attttgtatc aaatcaggaa ataatagata agctaagccc
       61 agaatcaaaa gtaccgctag aagaaaccag ccgattgttc ctatgaaata ctttaatttt
      121 tcgaacattg tatcacctcg ttgtcagtat atcacggatc agtaaattgg gggtgttaag
      181 aatctcctaa aatagacaaa atttgttcta ttttcctaaa gcaaatactt gtaagataca
      241 gtaagtgata ccagaagcaa tgaccggtcc ggcggcgatt cctcttaaga agacaacacc
      301 taaaatcgtg ccgaaaacaa gtgcaacagt gatttgtgga tcagaagcaa tcaatcctac
      361 acccttggaa gataagacag ccactagccc accgcaaaaa acagctaccc agccaatagg
      421 ggatttaaag gcttctaata gatcacgtag accgatttct cctgttgcga tagggattag
      481 aatagccgct gtgatgatcg tcaccccaat attgattcct ttgccttgaa gccaagggaa
      541 aaaggaacgg gaggctggta tgagcttcat aatcaaaaca aaagctgccg ctatcatcag
      601 actttgattt ttagctaaaa ttgctacaag taaaataatt cctaaaaaaa gccaactttc
      661 catgaaatat attcctcact ttcttcgaaa caatcataac atgtttttag aaagttacaa
      721 aagtaggaat tcatccttca agacctattc ataagctgtt tttttcataa aataaacaaa
      781 atcataaaaa aacactttgc ttatttgaca gaagacagcc gcgctttgta tagtggacaa
      841 gacttacatt tttttgaaga atcagaaaga tcaggtaaag gtcttagtaa acgcaagcca
      901 ttcagaataa ccaatattgt gcttccttcg tgtcctacaa ctccaagagg tagatttaaa
      961 aattgcagga agttagaagc aatcaacaag agaataacaa gaatcgaaaa aataatattt
     1021 tgtttgatga tccgccgcat ttttaaagat agccgatgac tgtagacaaa tttatttaag
     1081 tcgcttttca ttaagacgat gtctgcgata tccatagcgg catctgtccc ttgccccata
     1141 gcgacaccta aagaagcggc tgctaaagca ggcgcatcat tgactccatc accaaccatc
     1201 gcatttactt ggtaaagttc attctctttt ttgactagtt gtgttttttc ttccggagta
     1261 cagcttgcat agtaatgttc aatccctact tgttcagcaa tggcctttgc tgtgccagaa
     1321 tggtcgccgg ttatcatact tgtatggatg ttttgggatt taaagtagga aattacttgt
     1381 tgggtatttg cttttggaat atctagcaga cctaaaacag caattaactg ctgatcttta
     1441 gaaagataaa tcacggtttt gccttgattt tccaaacgtt cgatcatttc cgcaatctct
     1501 ttgctgatta tcatcgtctc aggatcatat gcgtgcttgc caactttaca ttgcgcacct
     1561 aaataggtag tttgtaatcc aaaaccagta atttcttcta ttggtaagta ttggatttct
     1621 tcaggtattg tgcaatcgaa atattgcaaa atcgcatgag caagtggatg cgtcgttttt
     1681 tgttccatag caacaagaag ttgttgtgcc aaatcctttt catcaaagaa aaagctgtca
     1741 gttacaactg gttttccttt agtgagcgtt cctgttttat caaaggcaat cgcttttaat
     1801 tcagaaagct tttctaaatg gataccgcct ttgattaaaa tcccattttt tgcagaattt
     1861 gaaagagcag ctagagaagc tggtgtagca gatgcgacaa gcgcacaagg agaagccaca
     1921 actaataata ccattcctcg ataaaagctt tcatcccaac tccaacctag gaaaaagtgg
     1981 gggagaagga tcattagagg aacagcaagc aaaatcaatt ttacataatt attttcgatt
     2041 cgttcgataa atgaagctgt ttgagttggc gtattctgcg cttcttctac taattggata
     2101 atcttagcaa agacagtttc ggaactcgtt tttgttactc gaatcgtgat gggatttcct
     2161 tgattcagcg ttcctgcata catctcatcg cctaaatatt tttctacagg cacagattca
     2221 ccgcttaatg cagactcatc gatcgttgcc tgtgtgcttt ctaaaaagcc atctatcgga
     2281 acagctgctc ctttagcgac aaataccaag ttatccacct ttagttgaga aacatctact
     2341 tcttgcattt gtccattttc ttttaataat tgggcttttt gtggttgaag attcatcaaa
     2401 gcagtaattt ctttttgact tttattagtt gtgtattcct ctaatgcacc gcttaaacaa
     2461 aagatgaatg tcaacattgc tccttcaaag taattaccga tcaaacaggc accaatagca
     2521 gctaaagcca tcaataaatc cacattcagt gtccgatcat tccacaattc tttcaagcct
     2581 tccgatgttt gtttatatcc accgatgata atggcactga tataaaaaag tggggtgatg
     2641 gtaagagaga atcggtcgaa gataaaaccg aagatcataa ataaaaggca gccgattgtt
     2701 gctgcaaaag cttttttctg attagtcatc gttattagac ctccttgtca aaacaaggat
     2761 agcataataa aaatgtaatt gataataata acagctaaat gagaacgata atggttatca
     2821 tttggtgatt aagcttgatg ttgtttttat tatttataat gattattatt aaagaaaata
     2881 aaaaaccaga acatttctca aataagagaa gtgttctggt tttttctaca ttgcaataaa
     2941 ccaataacca atcaaaatga taccaaggat aatacgatac cagccaaaag cggtaaagtc
     3001 gtttttcttc aaatagctta gtaagaattt gatagctaag acggaaacca caaaagatac
     3061 gaatgttcct acaagaagaa caacagtttc ttccattttg aatgaattcc cttcagctaa
     3121 atatttgacg atcttcaagc cgcttgcgcc aaacatgaca ggaatcccta agaaaaatga
     3181 aaactctgta gcgacaaaac gcgaagcacc aatcaagata gatcctagga tcgttgcgcc
     3241 agaacgggat gttccgggaa caagtgccaa gacttggaat aacccaacaa gaagagctgc
     3301 ttggtacgta aagtcattca gagaagtcca acgaggtgtt ttgtttttgt tgcgtttttc
     3361 gacaataata aaggcaatac cgtaaacgat caaaacaatg gcaactggta agaacttgtg
     3421 gaaatttgct tctaaccaat catccaaagg caaaccaatg atgatggctg gtatgcaagc
     3481 aacgatcact ttaaaccaaa gtgtccacgt atcttttttt tctaccgttg atttacttgg
     3541 agaaaatggg tttaacttgt gaaaataaag aacgacgaca gccaagatcg cccctaattg
     3601 gataacgaca ttgaacatcg acataaattg tgaactggca tccagtttga tgaattcatc
     3661 tgctaggatc aaatgaccag tactactgat gggcacccat tccgttattc cttcaataat
     3721 accgagaatc actgctttga taatatttgc aaaaaacata aattccttcc ttcccaatta
     3781 agatacatct tatagtatac cgttattttt tgagaaaccc aatctgtttt ttaatattaa
     3841 gaaaaacttg agaaataaag cagataagta cacgaagaga aaaaagaaga caaagccctc
     3901 gttcagactt tgccttttat gattctctgg taaaaattaa aatatcccca ttatagaaac
     3961 gagtcgcgac tatgtgtttt cccgttatcg atataagacg tatcattgat gccgtggata
     4021 gaaaatcgac cgtttgcata agtgaccttt gttacgctgc catttaaaag cccagcacga
     4081 acaggctgtt taggatcgat cagattaagc aaaaaggcga tcgtcaaacc atgagatacg
     4141 actaaaacat ttccaccacc atttttttcg cagtgatggg cgatatcttc aaatcctgtc
     4201 catacacggt ctcgcaatgt ttcataagtt tccgcccacc cagcggtatc taagttgtat
     4261 acagcattag caatttgttc aaaagaaact tctgtggtaa acatttcatc atatgtttta
     4321 aaattcaata cacgagggat cacaccccac atttccatgt catatccacc ttcaagagac
     4381 ccgaaacacc attctctaat ccttttttca ataaaataag gaatttcttt tcccttagaa
     4441 tgttctccta gaataatacg ggcagtttcg attgcacgac cactgtcact agaataagca
     4501 aatgaaaagt cgacattttt taacccgcga cctaaataat gaatgccttc ttgtccttgc
     4561 tttgtgaggg gtgtatcaca ccagccttgt actcgttcaa ttgtattgaa catcgttttt
     4621 ccgtgtcgta cgatataaag tgtagtttct gtcattttat tctcctccta agtcgtttta
     4681 acgattgaaa aaaggatttg tccttttttc ctgttcaatc gtcgttgcat cgccatgtcc
     4741 tggatagact gcaaattcat caggtaatac aaacagctgg gtccgaatac tatgaagtaa
     4801 ttgttctaaa ttccctgtat acagatcggt tctaccgata cttcctctaa acagggcgtc
     4861 gccagaaacg acaaaatcat caaaaataaa gctgacgctt cctatagaat gccctggggt
     4921 agggacgacg cgaaaagaca tgtttcctaa agtataagtt ttcatttcaa attcatattc
     4981 tgcaggcgag acaataacat cagcaatatc atcatgtcta ccgagtccag aaagattcaa
     5041 aatcggatca cctagccatt tttgctctag tgggctgaca taaactggga tttgataata
     5101 cgcgcgtaaa ggttccactg caccgatatg atcgtagtga gtatgggtaa gcaaaatcgc
     5161 taccggctgt tggtttgttt ttttgatttc ttgtttgatt cgttccgcat cttctccagg
     5221 gtcaatgatc aaaagtgctt cttcgttgta gaccaaataa cagttttctt caatcattcc
     5281 tgtttttaat ctttcgatat gcatgtgcat tcctccttga tagccaaaac ttctttcatc
     5341 cattagtata acgcattcat tgctaggaaa caaaaacagg tacttatttc tctttactta
     5401 tctgaattat cagactatat gaaaagtatt tggatattct aaagagaagg aaagtaagtt
     5461 ttcatagcat tttaatatgt ccttgttaca ttagattcat ccaaaaatcc aaattctata
     5521 tcctatatcc ctgcctaatc agcagggtgt ttttttatgt ttggaaagag agctcttttt
     5581 gctaaactag gttttttcag gtaatcttag agagaaagag gtggtggaaa tgatcaaaca
     5641 gtcaaaaata tctgtgcggc acttagtaga atttattttg cgacgtggaa gtatcgacaa
     5701 tcgtaaaaaa agtaaccata ctgcattaga aggagcgaga atccaccgca agctccaaaa
     5761 agatgcggga gaaaactatg aaaaagaagt ctttttaaaa acaacagttc aattagatga
     5821 atattacctg atcgttgaag gccgtgcaga cggtattttc aaaagagacg gtatttatta
     5881 tatagatgaa atcaaaacct ccgaaccacg atttgaagat ttagaaccag aacaagtgga
     5941 acttttcttt catcaagcaa gggtgtatgc ctatatctat agtcaagaac atgatttaca
     6001 agaaataaat ctgcaattga cttacttcca gacggcagaa gaagtgatca cgagaaaggt
     6061 tgaacatcag acaagagagc agttagaaac tttttttaaa aagctgactg aagattataa
     6121 agaatggctt gtttttcaag aaaactggcg cactgtacgc aatgcctctt tgatggcttt
     6181 gaaattcccc catgatgagt ataggaaagg tcagcgtgaa ctagcggtag ctgcttataa
     6241 aacgatccgt acgaaacaga aattgtttgt agaagcacct accggaacag gaaaaacaat
     6301 ctctacgtta ttccccgctt tgaaagctgt aggggaagaa gagggagaaa agatctttta
     6361 tctaacggct aaaacaataa ctagacaagt agctgaagat gctatgacag cattaaaaga
     6421 tacaggagct gaagtaaaaa gtgtcacttt gacggcgaaa gacaagatct gctttttaga
     6481 tgagacgacc tgtaatccag atcagtgccc atatgccaat ggttattaca atcggattaa
     6541 tgaaggttta tgggatcttt tgaatcatga gaatcagatc actcgtgaag tcatcgaaac
     6601 ttatgcaaga aagcatacac tttgtccttt cgaactatca ttagatgtca gtatctggtg
     6661 tgacgtaatc attggggatt acaattattt atttgatcca actgtttatt taagacgttt
     6721 ttttgaagat gaaaaaaacg aggactatct gtttttgatt gacgaagcac ataatttggt
     6781 gaatcgttcc cgagagatgt attcggcaga actatcttat gaaaaaacga aacgaagtaa
     6841 ggaagctata ccaaaggaat tcaaaaaact tcatcgccgt ttcaacaaac tattaaaaga
     6901 atttgattcg atccgagaaa tagcaaaaga agatcattgg gattatcatc atcaaaaagc
     6961 accggctgaa tctttagtaa aggcaggtta tcaattaagc gaaaaaatta aagaatggct
     7021 ggcagaattt cctgagcacc catcacaaga acaattgctt ccttattatt ttgatttgct
     7081 tcattttttg aaggtcagtg aattttatga tgatcactac gaaacaacag tcgaaaaaac
     7141 gtatcgcgat ctgatagtaa aagagttttg tattgatcca agcttgtttc ttgagcagtc
     7201 gttggataaa ggaaaaagca gtattctttt ttctgctagt ttttcaccac tctcttatta
     7261 tcaggaaaca ctggggggac aaaaaagtct ggcttacaaa ctgccgagtc ctttcccaga
     7321 aggaaaccag caagttttca tcgcaaatta cctagagacg acttatcgaa aaagggaaca
     7381 cagtctggca aaattagtag agacgattca tgcttttgct gatggaaagg tcgggaatta
     7441 tttcgttttc tttccttctt atcaatattt agatcttgcg gtggaagcat tcagacagca
     7501 atatcccgac agcaatgtgc taatccaaga aacggacatg aatgaggaag aacgcgaacg
     7561 atttttaaca aaatttcaaa caaatcccgc tgaaacattg attggatttt gcgtacttgg
     7621 cgggattttt tcagaaggaa tcgatttgag aggggaccga ttgatcggca gtatgatcgt
     7681 aggtgtaggt ttgccgcaga tgaatcatga gcaggaactg atcaaatcat attatgatga
     7741 gaaggaacac cttggatttg cttacgctta tcagcttcct ggaatgaaca aagtcttgca
     7801 agctggtggt cgagtgattc gtggcatggc ggatcaagga atcgttgtat tggcagatca
     7861 acgattttct agtttttctt atcgacgttt attcccacaa cattggcaaa cagcaagaga
     7921 agtacgaagt gttggggaat tggaagaagg aatacagcgt ttttggttat caaaagaagc
     7981 agtaaatcaa aaaaacgagg aatgacagac gtcagcctcg ttttttgatt aacgatagtt
     8041 agtgaattgc aactcgattg gtaagtcaag tttacgtaat aaagcaatca cagcttgtag
     8101 atcatcacgg ttcttacctg tcactctaat ctgatcttct tggatttgtg cttttacttt
     8161 cagtttttca tttttgatag ctgtagtgat tttcttcgcg ttttcacgat cgattccgtt
     8221 gaccaaatcg gcagtttgtc gagctttgcc acctagagcg tgttctgatt cggaaaaatg
     8281 gatatttttg attggcacat ttcttttgat cagcttacca aataatacat ctttgatctg
     8341 ttcgattttg aaatcatcat cgctcaatac aactagattg ctgttctcta atttgatttc
     8401 tactgtagaa tccttgaagt caaagcgatt ggacaattct tttgttgttt gctgaatcgc
     8461 attttttact tcttctgtat tgacttctga tacaatgtcg aagctagcat cttttgccat
     8521 aggaaccctc ctgatataca tataaatatt taccatacat ctatcttatc ataggattag
     8581 ggcagattct tacctgtttg ctaaaattct tctcatttga gttcgaagta ttttatttta
     8641 atagataaac tgttattctt acatttggaa taccaaagta ggggagaggt gcttgtgagt
     8701 aaaattatga ctgcgtatca taaaaatgaa agattaaaga aaatagtggt tattttgata
     8761 accggattga ccgctgcggt cgctttaaat tattttttga ttccagccaa tgtcttttct
     8821 gcagggatga atgggatcgc tcaaatcatt tcctcgcttt tatatgaatg gtttcatatc
     8881 aagatagaca caggaacatt tatttttctt ttgaatatcc ctgtgtttgt attagggttt
     8941 ctcaaagtag gaaaacgagc aacgatcctt agttttgtga atgttgtatg tgtatcggtg
     9001 atgacgatgc tgcttccagt cggacagatc actgataata ttttgatgaa tgccctagta
     9061 ggcggtgttt tattaggtct tggcgtagga ttatctttaa aaatgggctt tacaactggt
     9121 gggatggata tcatctctct tgtactttca caaacaactg gaaaaacagt cggaaactac
     9181 atgctgattc taaatggtat cattgtagtc atcgcaggct tcttctttaa ctgggaaagt
     9241 gccttgtata cgattatttc catttatgca atgactcaag taattgatgc catccacacg
     9301 agtcatcaaa aagtaacagc aatgatcgtt accgtcaagc cagaagaggt aacagaagaa
     9361 ctagcaaaac ggatggtacg tggaatgaca ttactgccgt ctgtcggtgg ctattcaaaa
     9421 aaacaaggga acatgatcat gatggtcatc acccgctacg aaatgtatga tcttgatcag
     9481 atcgttcatg aaatcgacga cgatgcattt atcaatattt taccaactca ttcagtattt
     9541 ggccggtttg caaatgaaaa cgaacaaaaa atgtatcgaa caactggcgt attgccagaa
     9601 ataaaaaatc gttcacaaaa aaaatgagga atcaggttta ttttagaata aatttaatct
     9661 attacatcta ataagaacat ttttataaat ttaaacgaga atcttacttc taaattctca
     9721 tttacaagca gctaaaaaaa gagtatgata aataaaaatc gtgttaagga gtgtcgtacg
     9781 atgagcgaag caaaccaaga acggtctgga caagaaatag aactaatcaa agaacgtatt
     9841 cttgctgcct tggaaatggt gattgatcct gaattaggaa tcgacatcgt caatttaggc
     9901 ttgatttatg atatagaatt caatcctgaa aatggagaaa cagtcattaa gatgactcta
     9961 acaactatgg gctgtccatt agcagatatt ttaacagaat ctatccatga cgcattaaaa
    10021 gaagtgccag aagtaacgaa agcagaagtc aaactagtct ggtatccagc atggacgaca
    10081 gataagatga gccgttatgc acggattgcg ttggggatac gatagaaatc ttggctgact
    10141 agctatgaga agcaaatagg aaaaacaaaa aagcctttta tcctttctag aagaaaaga
//
LOCUS       DAKCAA010000081        10001 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000081 DAKCAA010000000
VERSION     DAKCAA010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.082"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            76..3669
                     /locus_tag="OUE31_002381"
     CDS             76..3669
                     /locus_tag="OUE31_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HCU0223356.1"
                     /translation="MIRNKKLCLKVALLAVFCQVFFLVGSLTTQAEEITQGTTVSQVS
                     PTSNEVEVQSDLPKETAKEEISTEFVPPTEAPSMNEKSVLDETIGKSQQPGDSPVVAE
                     EIPIETPEVQTIFEKENSSEKSCSTVINEGTESVQSEDSKEATTPIELTKEEMNSNTS
                     LSSEKEEKTALSTESHEPELKKVEESGDTQKEKIKKEAVSSTSSKEVTLIVPQTARSA
                     RVRRATNTAVLGGRKIDWGENIGVISSANNPNFTLNYMVRFEINGQVAFCIEPGVAAA
                     EGQVYTATALENYLKDLNIRKKTSLISYLGYVTSKDKSDEQYIAAQFMIWEVLGTKIP
                     IKNIRIDYDRRKAEIQRLLNNFDVRATFHNQTHTVKIGETLKVKSGNDFLQRVKDIQK
                     PKGVNVSIHDNEVWITITKESPEKAKIHFNQIEALGVPLAYRRPGAQTIGVLNPFVPG
                     DSVVNLTILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQANGKKIKEITLKNING
                     KVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNTIAKDQVIKGTIDLV
                     KVANKDLVDSTNPDNKPKLAGIEISLTSKTTGKVVKTVVTDNDGYATFGKNTVVFDTY
                     ILSETKGKEGYKLFEPFEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKVIALAG
                     TQFKIWDKYANNGKGGYVSMALPNDTEVSDIFTTNEKGYFVTTDTLKYGKNRYELREI
                     KAPEKYVLNKTPYVFSVTDDTNTIQLIYFANRLAKANVEVFKYDTSTNFDQKTAIAGV
                     EFDLFKKDETGTTFVGTFKTDKKGKINVKDLLVGDYFFKEVKPLAGYLALDKDVPFTV
                     TVDKDGTVIALEVENKRIPPKIGTTAIGKYTNQQKVTPLKKVTITDTVKYSNLIIGKT
                     YTVNGVLMDKEESITAGKDVPLLVNGKQITASKVFVAKNPNGMISLDFVFDASALAGK
                     EIVVFENVYRDGRLVASHTDIHDKGQTVRIVNPMIHTKATGQNGEKQLQALPNQKVKE
                     LVQLNDLIVGQTYKVLVQGYITPDGVKLDGTSAEKIFKADKTTLEFLFEFLVDGRKLA
                     GKGLSFAEWLEAQSEPKDENDYEVRFEQIANHNVDLKSEDQTVYFVEVPKVPEPKIPE
                     KSQPFKEVKQASVVPMLPKTGSEDTVLWMIIGVLFVLAAGLTFYELRKVKD"
     gene            3769..4707
                     /locus_tag="OUE31_002382"
     CDS             3769..4707
                     /locus_tag="OUE31_002382"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCU0223357.1"
                     /translation="MKKKERKKRMKKLFFACLFSSVVLAGGINVFADEIGITPVTPPV
                     IEETTPVVPIPDISKIDESVPDQPTPVDPDISSEVTEPTTPVVPDITENSENETPVVS
                     PSTGETTNDKDTTPTTSESYSGTSSVDNDSKIDDFSSSSTTIDTPKETEKKNDLGAPK
                     NLTPENHIKTVSEKEMTVSVSSDGKIVQGTGTEKSIPIVTSNLEEINHVPTSETPLQV
                     ATGQAIVGVQDGVPLVQDNQGNLVEDLSIPVKKLPSGNIEIKTIDGKTKVLPKTGEEL
                     QISLTILGSLLTAVTGGIFYGKKQWRHLRHMFKKTI"
     gene            4726..5076
                     /locus_tag="OUE31_002383"
     CDS             4726..5076
                     /locus_tag="OUE31_002383"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223358.1"
                     /translation="MGLSYVAISQEEVLGKCFNQKHVGSTGERDHRGNMKKVEWEIFQ
                     MNSEKMGEIEVRVAVGGAPKAMRYNAEVLLANPRISRRADVRNIGNDGETNKIARNRF
                     YLLVDRVEVKGGNN"
     gene            5076..5507
                     /locus_tag="OUE31_002384"
     CDS             5076..5507
                     /locus_tag="OUE31_002384"
                     /inference="COORDINATES: protein motif:HMM:NF017895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF961 family protein"
                     /protein_id="HCU0223359.1"
                     /translation="MTLEFDQGIVPGLVKETLGEIYFVKAQRPRMLYEDNENTGEIKE
                     RPVEFSSATQETMFVVNFPPKTNLDGLSFGDVVELEEVEFRFWISIDRESMSNRAEND
                     LKVSALRYKKTGKNVFQTSSSTRATYVKEKQDSNKESAKKE"
     gene            5775..7094
                     /locus_tag="OUE31_002385"
     CDS             5775..7094
                     /locus_tag="OUE31_002385"
                     /inference="COORDINATES: protein motif:HMM:NF013727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HCU0223360.1"
                     /translation="MFQYKGIRIRNRHKYASERFIFYLMLPVLLLMSGFFSLFYTTIT
                     WEWCCIYWIIAFGLAGLFAYMCLYFYFYNVYQRLVHKGKLAKMIHSRRLILERVLKNG
                     RRKVVYYPKIFYHYKNGLIHVRLPLDLGPFQDRFNEMAGQLEEAFFCDLVEEQREKNY
                     ICYTFLYDVEKNRIGIRDITVKDGIITLMKNVQWAFNKAPHAIIIGSTGGGKTYFIMS
                     LIYALLPYGTFDICDPKRADLASLEKIPIFKDQVFYGGGILSCLINLAKETANRYDFL
                     REQPEYELGYDYTYYHLTPHFLVIDEWAAYYASLDTKEKKKAMGCLNQIALMGRQCGV
                     FLILGTQRPDTKYLDGAIRDNFGLRVTLGRVSKAGYKMIFEHTVKSLFNKPIKGRGYI
                     DSGTDQVREFYAPFIDITRFNFFAEFKQLSDQLMAEKIKETKEGKNV"
     gene            7087..7251
                     /locus_tag="OUE31_002386"
     CDS             7087..7251
                     /locus_tag="OUE31_002386"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223361.1"
                     /translation="MYEEIPATCGTRLGIKDLMIDSFLAIVFSEKRLSFFINKKVENR
                     WRVERMYPTS"
     gene            7790..8965
                     /locus_tag="OUE31_002387"
     CDS             7790..8965
                     /locus_tag="OUE31_002387"
                     /inference="COORDINATES: protein
                     motif:HMM:NF013540.1,HMM:NF014537.1,HMM:NF037191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCU0223362.1"
                     /translation="MDGTQLKQMRLSRNLTQKLVADTLGWPQSFLSMIENDQRSCSKE
                     QEEALCEFYANFSSFTSLEIKFDYVRVRVPTNDTKTVVEEILGMDFNSFFYAETRLYG
                     YIEMYQKGMIRVLNSKKGDDKGVLIELSGQGCRNYESVLDERNDSWYQFFTRCVSFNG
                     VSRRIDIAVDDFEELFSLHEFAQKLNRGEFDSKFRTWRFQEEKQLLDNLSSGLSVYLG
                     SSQSLMYFCFYQKNYEIAKKQKLPLEEVEVKNRYEIRLRDAKAVSFIEQYLNKVDFSD
                     LTMGILANQLIMFEGEKNTNVWKPWGKLIQNVGKVNLTVTPEKPNYNRKLMYLKTQPA
                     RTMKIVKTVDEILGLNRFGEILEETELREQDEKIVEDEVRAVYEYIQENPDAIHYLL"
     gene            9470..9667
                     /locus_tag="OUE31_002388"
     CDS             9470..9667
                     /locus_tag="OUE31_002388"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223363.1"
                     /translation="MGQYFLTGVWYVLKLVIILGIAYICFRILLSGEGMPTPKDFIIS
                     VLNFVADQIQVIIHWAQQRFG"
BASE COUNT         3603 a         1417 c         2037 g         2944 t
ORIGIN      
        1 aaatagttta cgtcgatact tattaagtta tcgacgtttt ttttataaaa aatttataaa
       61 aggaggtttc ttgatatgat aagaaacaaa aagctttgct tgaaagttgc tttattggca
      121 gttttttgtc aagtattttt tttggtaggc tcactgacaa cacaagcaga agaaataact
      181 caaggaacaa ctgtttctca agtttctcct acttcaaatg aagttgaagt acaatccgat
      241 ttaccaaaag agactgccaa agaagagata tcgacagaat ttgttccacc aacagaagca
      301 ccttcaatga acgaaaaaag cgtactcgat gaaaccatcg gtaaaagcca acaaccagga
      361 gatagtccag ttgtggcaga agaaatacca atagaaacac ctgaagttca aacaattttt
      421 gaaaaggaaa attcatcaga aaaaagttgt tctactgtaa taaacgaagg aacagaatca
      481 gttcaatcag aagattcaaa agaggcaacg actccgattg aattgacgaa agaagaaatg
      541 aattctaata cttcactttc ttctgaaaaa gaagagaaaa cagctctttc gacagaatcc
      601 catgaacctg aattgaaaaa agttgaggaa tcaggtgata cacaaaaaga gaaaataaaa
      661 aaagaagctg tttcttctac ttcttcaaaa gaagttacat tgattgtacc acaaaccgct
      721 cgaagtgcac gggtgcgacg tgcaaccaat acagcagttt tgggtggtcg gaaaattgat
      781 tggggcgaaa atattggtgt tatttctagt gccaataatc ccaatttcac tttaaattac
      841 atggttcgtt ttgagattaa tggacaagta gcattttgta ttgaacctgg tgtcgcagcc
      901 gcagaaggtc aagtttatac agctactgct ttagaaaact atttgaaaga tttaaatata
      961 cgaaaaaaaa caagcttgat ctcttattta ggatatgtca caagcaaaga caaatccgat
     1021 gaacaataca ttgcggcaca atttatgatt tgggaagttt tgggcacaaa aattccaatt
     1081 aaaaatatcc gtattgacta tgatcgtcga aaagcagaaa ttcaacgttt gcttaataat
     1141 tttgatgtaa gagctacttt tcataatcaa acacatacgg taaaaattgg cgaaacgtta
     1201 aaagtaaaaa gtggcaatga ctttctacaa cgtgtaaaag acattcaaaa gccaaaaggt
     1261 gttaatgtat ctattcatga taatgaagta tggattacaa tcacaaaaga gtcaccagaa
     1321 aaggcaaaaa ttcatttcaa tcaaattgaa gcattaggcg tgccattagc gtatcgtcgt
     1381 ccaggtgctc aaacaattgg ggtgctgaat ccttttgtac ctggtgactc tgttgtcaat
     1441 ttgaccattt tgaaacaagg aaacattcgc gtctttaaag aagatgcaga aaccggtgtg
     1501 aaagcacaag gtgcagcttc tttagaaaat gcagtgtatg gcttgtatca agcaaatggg
     1561 aagaaaatca aagaaattac attgaaaaat atcaatggca aagtacaggc agaaatcaaa
     1621 gatcttgatc ctggtaaata tgttttaaaa gagatcaaag caccaaaagg ttatgtactt
     1681 tctgatgaag caattgaaat cgtcgttgaa cctggaaaaa ctgtcaatac gatcgcaaaa
     1741 gatcaagtga tcaaaggaac cattgattta gtcaaagtcg caaataaaga tttagtcgat
     1801 tcaaccaatc cagacaacaa acccaaatta gctggtattg aaatctcttt gacgtcaaaa
     1861 acaactggaa aagtggtgaa aacagttgtg acagataatg atggttacgc tacttttggt
     1921 aaaaataccg ttgtctttga tacgtacatt ctttctgaaa ccaaaggaaa agaaggatat
     1981 aaactatttg aaccattcga agtcacaatt tctgaaaatg gacaaacctt ccattatgtt
     2041 ttagaagaca aagtaatcga acaacgtctt aaagtggtga aagtggatca agaaacaggg
     2101 aaagtcattg ctctagctgg tacccaattc aaaatttggg ataaatacgc aaacaatggt
     2161 aaaggtggct atgtatcgat ggcattaccg aatgatacag aggtttcaga catatttaca
     2221 acaaacgaga aagggtactt tgtcacaacg gatacattga aatacggaaa aaatcgttac
     2281 gagttgcgag aaatcaaagc acctgaaaaa tatgttctaa ataaaacgcc ttatgtcttt
     2341 tcagtaacag acgacaccaa tacgattcaa ttaatctact tcgctaaccg tttagcgaaa
     2401 gccaacgtag aggttttcaa atatgatact agtacgaatt ttgatcaaaa aacggcgatt
     2461 gctggtgttg aatttgacct attcaaaaaa gatgaaacag gcacaacctt tgttggtaca
     2521 ttcaaaacag acaaaaaagg taaaatcaat gtgaaagact tattggttgg cgattacttc
     2581 tttaaagaag tgaaaccatt agcagggtat ctggccttag ataaagacgt accatttact
     2641 gtaacggttg ataaagacgg tacagtgatt gcactagaag tggaaaacaa acggattcca
     2701 cctaaaattg gtactacagc tatcggtaag tatacaaacc aacaaaaagt gaccccattg
     2761 aaaaaagtaa cgattacaga cactgtaaaa tacagtaatc taatcatcgg aaaaacttat
     2821 accgtcaatg gtgttttgat ggataaggaa gaatctatca cagcaggaaa agacgtaccg
     2881 ttgttagtaa atggtaaaca aattaccgca agtaaagtgt ttgtcgcaaa aaatcctaac
     2941 ggaatgattt cccttgactt tgtctttgat gctagtgcat tagctggaaa agagatagtc
     3001 gtatttgaaa atgtctatcg tgacggacgc ttagttgcgt ctcatacaga tattcacgat
     3061 aaaggacaaa cggttcgtat tgtgaaccct atgattcata caaaagcaac aggtcaaaac
     3121 ggcgaaaaac aattacaagc tttaccaaat caaaaagtga aagaattggt acagttgaac
     3181 gacttaattg ttggtcaaac gtacaaagtg ctcgtacaag gttatattac acctgatggt
     3241 gtgaaattag acggtacaag tgctgaaaaa attttcaaag cagataagac aactttagag
     3301 ttcttatttg aatttttggt agatggacgt aagctagcag gcaaaggatt atcttttgca
     3361 gaatggttag aagcccaaag tgaaccaaaa gatgaaaacg attatgaagt tcgatttgaa
     3421 caaatcgcaa accacaacgt agacttaaaa tcagaagatc aaacggttta ttttgtagaa
     3481 gttccaaaag taccggaacc aaaaattcct gaaaaatcac aaccttttaa agaggtgaaa
     3541 caagcttcag tagtaccaat gttgccaaaa acaggatcag aagatactgt attatggatg
     3601 atcattggtg tgctatttgt tttagcagca ggtcttacat tttacgagtt acgcaaagtc
     3661 aaagactaag taggacaaac aagcggttag atgcctaatc gcttgtttgg ttttaaaaaa
     3721 gttattgcat aagtaacctt tgaaaagata agaaatgatc tttgttttat gaagaaaaaa
     3781 gaaaggaaaa agagaatgaa gaagctattt ttcgcatgtt tatttagttc cgtagttctt
     3841 gctggtggaa taaacgtttt tgcagatgaa ataggtatta caccagttac gccacctgtg
     3901 atagaagaaa caacacctgt tgttccaatt ccagatattt ctaaaataga tgagtctgtt
     3961 ccggatcaac caactcctgt tgatccggat atatcttcag aagtaactga accaacaaca
     4021 cctgttgttc ctgatataac ggaaaattca gaaaatgaaa caccagttgt atcgccttct
     4081 actggagaaa caacgaatga taaagatact acaccaacta ccagtgagtc ttattcggga
     4141 actagttcgg tagataatga ttcaaaaata gacgatttta gttcttcatc tactacaata
     4201 gatacaccaa aagaaacaga aaagaaaaat gatttaggag ctcccaaaaa tttaacacct
     4261 gaaaatcata taaagactgt atcggaaaag gaaatgactg tttcagtcag ttcagatgga
     4321 aaaattgtac aaggaacggg taccgaaaaa tcaattccta ttgtgacaag taatttagaa
     4381 gaaattaatc atgtcccaac atctgaaact cctttacaag tagcgactgg tcaagcgatt
     4441 gttggggtac aagatggtgt accacttgta caagataatc aagggaattt ggtagaagat
     4501 ttatccattc ctgtaaaaaa actacctagc ggcaatattg aaatcaaaac aatcgatggg
     4561 aaaacaaaag tattgccaaa aacaggtgaa gaacttcaaa ttagtttaac tatccttggt
     4621 tctcttttaa cagcagtaac cgggggcatt ttttatggta aaaaacaatg gcgtcatttg
     4681 cgtcatatgt ttaagaaaac tatttagtaa ggagagagaa taaaaatggg tttatcttat
     4741 gttgcaatta gtcaggaaga agtattggga aagtgtttta atcaaaaaca cgttggctcg
     4801 acaggtgaac gagatcatcg aggaaatatg aagaaagtag agtgggagat ttttcagatg
     4861 aactctgaaa agatgggaga aattgaagtg cgtgtagctg tcggtggtgc gcctaaagcc
     4921 atgcgataca atgcagaagt gttactggca aatcctagaa tttctcgtcg agcagatgta
     4981 cgaaatattg gaaatgacgg tgaaacaaac aaaatagcac gtaataggtt ttatttgtta
     5041 gtcgatcgtg tagaagtaaa aggaggaaat aactaatgac actagaattt gatcaaggaa
     5101 ttgtcccagg gttggtaaaa gaaacactag gagaaatcta ttttgtcaag gcacaacgtc
     5161 cacgtatgct gtatgaagat aatgaaaaca caggagaaat taaagagcgt ccagttgaat
     5221 tttcaagtgc tacccaagaa acaatgttcg tggtgaattt tccaccaaaa acaaatttgg
     5281 atggattaag ttttggcgat gtggtggaat tagaagaggt tgaatttcga ttttggattt
     5341 ctattgatcg cgaatcaatg agtaaccgag cagagaatga tctgaaagta tctgcgcttc
     5401 gttataaaaa aacgggaaaa aacgtttttc aaacgtcttc ctctactcgt gcaacatatg
     5461 taaaagaaaa acaagactca aataaagaaa gtgcaaagaa agagtaatgg tttccattgc
     5521 tctttcttat tttaaagcta gaagaagtag ctgatgtgga gaaaattgaa ttggctggct
     5581 atattattgg gataaatttt tgaattttta agaatttaga tagtggttag atacgattga
     5641 ttctttgtgt attttgtatt atttaagtat tgtgtggtat ttacattaag ttaatattga
     5701 tgttgttagt gttaatgaag gttttctttt atccaataca ttagtcactc tatgatgcga
     5761 ggagatgaga ataagtgttt caatataaag gtattcgtat tcgaaatcga cataaatatg
     5821 cttcagaacg atttattttt tatcttatgt tgccggttct gttgctaatg agtggatttt
     5881 tttctctctt ttatacaacg atcacatggg aatggtgctg tatttattgg ataatcgcat
     5941 ttggtttagc tggtctattt gcgtatatgt gtttgtattt ttacttttat aatgtttatc
     6001 agcgattggt tcataaagga aaattagcaa agatgataca tagtcgtcga ttgattcttg
     6061 aaagagtatt gaaaaatgga cggcggaaag tggtgtatta tccaaaaatt ttttatcact
     6121 ataaaaatgg cttaattcat gttcgattgc cattagattt aggtcccttt caagatcggt
     6181 ttaatgagat ggctgggcaa ctagaagaag cctttttttg tgatttagta gaagagcaac
     6241 gagagaaaaa ctatatttgt tatacctttt tatacgatgt ggaaaaaaat cgtattggga
     6301 ttcgagatat aaccgtaaaa gatggcataa tcaccttaat gaagaatgtt caatgggcat
     6361 ttaataaagc accacatgcc ataattatag gaagtactgg cggtgggaaa acgtatttta
     6421 taatgtcttt gatctatgca ttattaccgt atggtacgtt tgatatttgt gatccaaaac
     6481 gtgcagattt ggctagttta gaaaaaatac caatttttaa agatcaagtt ttttatggtg
     6541 gtggtatttt atcttgttta ataaatctag ctaaagaaac tgctaatcga tacgattttt
     6601 taagagaaca gcccgagtat gaattagggt acgattatac ttattatcat ctaactcctc
     6661 attttttggt gattgatgaa tgggcagcat attatgcatc gttagatact aaagaaaaaa
     6721 agaaggcaat gggatgtttg aaccaaattg ctttaatggg tcgtcaatgt ggcgtgtttt
     6781 taattttagg tacccaacgt ccagatacaa agtatttgga cggcgcgata cgagataatt
     6841 ttggtttacg tgtaacactg ggaagagtat ccaaagctgg gtataagatg atctttgaac
     6901 atacagtaaa atcattattt aataagccga ttaaaggtcg tggttatatt gattcgggaa
     6961 ccgatcaagt acgagaattt tatgcgccat ttatcgatat aacaagattt aacttttttg
     7021 cggaatttaa acaactatct gatcaattaa tggctgaaaa aatcaaggag acgaaagagg
     7081 gaaaaaatgt atgaagaaat cccagctaca tgtggaactc gattaggaat aaaagattta
     7141 atgattgact cttttttggc aattgttttc agtgagaaga gattaagctt ctttatcaat
     7201 aaaaaagtag agaatcgttg gagagtagaa cgtatgtatc caacgagtta actgattggt
     7261 tacagttgcc ttatgacaat tatcgaaggc gaatatgacg ggtttttact tcaaataaaa
     7321 gtgctcgatc ctatagtgac caaattgtcg aaaaagcagc ggaacagcct gttttttatg
     7381 gacgattcaa aggactttcc tgttcttatg ttaaaagtaa agaccggtct cgactgtacc
     7441 tacaagtaga ggatattaac ttgtcctttg cgttgccaga aaattaaatt tgtcctcatt
     7501 agaatacgga agatgctgtg cgtatgctcc acaagcaaac aagcctcagg gcggaaggac
     7561 gcggaagcgt cctagcgtta gcgaaagccc tgaggtgcag ggtgcgttgt ggggcgtgcg
     7621 cgtagcgcac gcctaaaacc cccatattct aacagggggg tagaatttat attcggtggc
     7681 aaagatgggt gattgaaaca ttgatataac actattttgc ttcaaaaatt ttgtgatatt
     7741 tttcttcgct ttgtaacata aaatatcaca aaagaaagga aagatatatt tggatgggac
     7801 acaattaaag caaatgcggt taagtcggaa tttgacacag aaattagtgg cagatacatt
     7861 aggatggcca caatcttttt tatcaatgat agaaaatgac caacgaagtt gctcgaaaga
     7921 acaagaagaa gcactttgtg aattttatgc gaatttttca agttttacga gtttagaaat
     7981 taaatttgat tatgtccgtg tacgagttcc gacaaatgat acgaaaacag ttgtggaaga
     8041 aattttggga atggatttta actctttttt ttatgcagaa acccgcttat atggttatat
     8101 tgaaatgtat caaaaaggca tgatccgtgt attaaattct aaaaaaggtg acgataaagg
     8161 agtgttgatc gaattatctg gtcaaggctg tcggaattat gaaagtgtac tggatgaacg
     8221 aaatgatagt tggtatcaat tctttacacg atgtgtctct ttcaatggtg tgtctcgaag
     8281 aattgatatt gcggtagatg attttgaaga actattttct ttacatgaat ttgcacaaaa
     8341 actaaatcgt ggcgaatttg attcaaaatt tcgaacctgg cgatttcaag aagaaaaaca
     8401 gttgttagat aatctaagta gtggcttatc tgtttattta ggtagttcac aaagtttgat
     8461 gtatttttgt ttttatcaga agaattatga aattgcaaaa aagcagaaac ttccgttgga
     8521 agaggtcgag gtaaaaaatc gttatgaaat tcgcttacgt gatgcaaaag cggtcagttt
     8581 tattgaacaa tacttaaata aagtagattt ttcagattta acgatgggga ttttagccaa
     8641 tcagttaata atgtttgagg gagagaaaaa cacaaatgtg tggaaaccat ggggaaaatt
     8701 gattcagaac gttggaaaag tcaatttgac agtgacacca gaaaagccaa attataatcg
     8761 gaaattgatg tatttaaaga cacaacctgc tcgtacaatg aagattgtaa aaactgtgga
     8821 tgaaatttta ggattgaatc gatttggaga aattttagaa gaaacagaat tacgggaaca
     8881 agatgaaaaa attgtagaag atgaggtgcg tgctgtttat gaatatatac aagaaaatcc
     8941 agacgcgatt cattatttgc tataaagctt gcgataagat gggtgaaaca tgattaaaac
     9001 agaagaccaa tgatggggag agtatatgat tgcttgttaa cgattaataa aagaaacgat
     9061 cctatgtgtt ggaaatgatc tacagttatt taaagaatat ttagattatc aacaatcaat
     9121 caaaatgtta catgtagaaa taggggaagt attaagctac cgtattagtg attcgttaaa
     9181 atattcgttg acaaagattt atttatatgc aacacaagta tgtggatata cgaaaaagca
     9241 gtaaaaacaa tgatgaaata tgacgatttg ccaagtaaga tatcctagat ttacaacaag
     9301 tattggaaga aaaactatat ctatatatga aaaatagagg ggaaaagaaa tgattcgatt
     9361 tttattttct gtaggttggc attttttgaa attactgttt cttttagttt gtattgtctg
     9421 tagtattatt tggttattaa cactttaaag aaaggaatat gttggaaaaa tgggacagta
     9481 ttttcttacc ggtgtttggt atgtattgaa attagtgatt attttaggta ttgcctatat
     9541 ttgttttaga attttattat cgggagaagg aatgccaacg ccaaaagatt ttatcataag
     9601 cgtgttgaat tttgtggcgg atcaaataca agtgataatt cattgggcgc agcaacgttt
     9661 tggataaaaa aatatattta aaaaatttaa tgtttagaag tgggctatgt gatagaaaat
     9721 ttcgagtata agttatctag attgccaaag aaaaagggag ctacacaaaa agagctggct
     9781 aataaattag gtgtcaatgt acaaagcgct tctaatgttg aggaagataa gagctaacta
     9841 catttagtaa tttagaaaaa atagtttctt tctttgatgc ttcatcgatt gaattatttg
     9901 gtacgaatag ggatcgaata attgcagatg ttccattaat attagaagat atggataatt
     9961 tatttaaaaa aatttgaatg atctttatga ctaaaaaagt a
//
LOCUS       DAKCAA010000082         9935 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000082 DAKCAA010000000
VERSION     DAKCAA010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.083"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..330
                     /locus_tag="OUE31_002389"
     CDS             <1..330
                     /locus_tag="OUE31_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HCU0223364.1"
                     /translation="MESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRG
                     VQQCQMYMAMTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVK
                     SCGLQVV"
     gene            1018..2895
                     /gene="ltrA"
                     /locus_tag="OUE31_002390"
     CDS             1018..2895
                     /gene="ltrA"
                     /locus_tag="OUE31_002390"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCU0223365.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            3026..3403
                     /locus_tag="OUE31_002391"
                     /pseudo
     CDS             3026..3403
                     /locus_tag="OUE31_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            3403..4608
                     /locus_tag="OUE31_002392"
     CDS             3403..4608
                     /locus_tag="OUE31_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCU0223366.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            4624..5268
                     /locus_tag="OUE31_002393"
     CDS             4624..5268
                     /locus_tag="OUE31_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223367.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            5279..6085
                     /locus_tag="OUE31_002394"
     CDS             5279..6085
                     /locus_tag="OUE31_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223368.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            6107..6337
                     /locus_tag="OUE31_002395"
     CDS             6107..6337
                     /locus_tag="OUE31_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223369.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            6894..7169
                     /locus_tag="OUE31_002396"
     CDS             6894..7169
                     /locus_tag="OUE31_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223370.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHELMDHRKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIE"
     gene            7211..7633
                     /locus_tag="OUE31_002397"
     CDS             7211..7633
                     /locus_tag="OUE31_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223371.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKPINESVHARVDPFDPTKFLKR"
     gene            7653..9245
                     /locus_tag="OUE31_002398"
     CDS             7653..9245
                     /locus_tag="OUE31_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223372.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKSLKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            9266..9601
                     /locus_tag="OUE31_002399"
     CDS             9266..9601
                     /locus_tag="OUE31_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223373.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            9747..>9935
                     /locus_tag="OUE31_002400"
     CDS             9747..>9935
                     /locus_tag="OUE31_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223374.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYPF"
BASE COUNT         3770 a         1537 c         2089 g         2539 t
ORIGIN      
        1 atggagtcta tcgtggaatc cttatgtgag acttatggca tgatttttga tggtcatagt
       61 acgattcgac accttgacca acaacagttg gtcttttttg acattgactc tattacaggc
      121 ctagatcgag gggtacaaca atgtcagatg tacatggcca tgacgttgat ttggaatcag
      181 gcattgattc aaggacgaag acaacgacgc ttaattaaag aaaaacaaat ggaagaacaa
      241 gacttcaaac gcttcttggc gatgattgat gagtgccata atggtgcgac ctgttctgca
      301 gtgaaaagct gtgggttgca agtagtctaa aaactattgt aataactctt ataacgagaa
      361 gtcaaatgag tgggtaacgc cacaaagggc ttccactgat actccgacat gcaacaagta
      421 gtttatgcag accaacgttg tgtgaagctc ggtgaagtcg gctgaaggat accgtaaggt
      481 aaaagaaata gtgaatacca cgaaagttct ctagaggtaa agggtgtatc cgataagtcg
      541 ggtgtccaaa aaaacttaat atggtgagta tgtacaaacg tactgacgaa ctagcgaatg
      601 tactgtccga aaggcatagc tcctagaaat gggagagaca gtgagcaaaa aatcactcat
      661 tgtgctaact tgtggttgag taaaagtcgt tgttatgaaa gaccatgctg cgttacaggc
      721 gtaggagaag ttagggggca aaagctagca tctaagttaa ggcatgtgga tagatataag
      781 ggaacagggg aagccatcaa catggagagt gcatactcga tgaagtggta gtaagaaata
      841 tgtgaatgac aaataactta ctttagtgat ggtgaaagta gagtcacgac tgatgaaggt
      901 tctgtaatgg aactggagga acaggctcga ttcgtctgta aaagtcatga aacccgttca
      961 accatgggat tctcgtatga ctaaaaaggt cacgagccaa ttggagcgtg ataaaccatg
     1021 acaaaagaaa caagtccaaa agataggaag ttgcggcatg cagaatatta tggcatgacg
     1081 gaaatcttcg ataagatata ctccaaaagt ttgaagggag ataatttcaa gaatctaatg
     1141 cagattatca tttctgataa caacattgtc ctagcatatc gtaatatcaa gagaaatcac
     1201 ggtagtgtga caagaggaga agatggagta acgattaaag atattgaaaa tctcaaccgt
     1261 aatgaattcg tagaaattgt taggaagcga ttcgcacatt ataaccctcg gaaagtaagg
     1321 cgtgtagaaa ttcctaaata taatggtaaa ttaagaccgt tgggtattcc atcaatatgg
     1381 gatagaatcg cgcagcaatg catcttacaa gtattagaac caatatgtga agcaaaattc
     1441 aataatcaca gctatggttt ccgcccaaat agatcagcag aacacgcaat agcagattgt
     1501 atggcccgaa tgaatcaaag tcacatggaa tatgtggtag atgtagatat caaaggtttc
     1561 ttcgacgaag tcaatcatac taaactcatg agacaaatct ggtctatggg tatacgagac
     1621 aaacagcttc tcttaatcat taggaaaatg ttaagagcac ccgtagtact tccaaatggg
     1681 aagttgatat acccaacaaa aggaacacca caaggcggaa tacttagccc attacttgcg
     1741 aacatcaatc tcaacgaatt tgactggtgg atagcaaatc agtgggagga aaaagatgcc
     1801 aaagagctaa aacatcattt taggaaaaat ggagcttggg ataaaggtaa tatctatcac
     1861 aagctcagaa agagtacaac tctaaaagaa atatacctag tgagatacgc agatgatttt
     1921 aaaattttct gtagaaatta taatgaagcg aaaaaagttt tctatgcaac taaaatgtgg
     1981 ttacaggagc gtctaaagtt accaatatct gaagaaaagt caaaaatcac aaatctttca
     2041 aaagaagaaa gtgaattttt aggctttacg atgaaattag tgaccaaagg taacaaaaag
     2101 gttgttaata cgcatatagg tacaaaagca caaagcatga ttaaagtgaa actaaaaaaa
     2161 caaatcaaac gaattcaaaa aagtcctaat agcaaagata cctttatcta tattggagtc
     2221 tataacagta tggttattgg gattcataat tacttcaaaa ttgcgactca ttgtagtgta
     2281 gcaatgcgaa aaattgcaag agaactcaga ccaagttttg aaatacgact acgagaacaa
     2341 ggaatctcaa aagaaggaca atacggaaag tacgaaggat acaagcctta cctacggtca
     2401 ggacaaatac gatatataag agggtttcca atattaccag tagggtatat tcaacacaga
     2461 catccgatgt gtaaaaaaag aaatattaat aaatacaccg aagaaggtag ggaagccatt
     2521 cataagaagc aacaaaccgt agaagaatgg aagatatcgt ggttgtgtag caatccagtg
     2581 cttagtaaga gagcaacgat tgaatttgcg gacaatcgaa tttcaaaatt catcgctcaa
     2641 aagggaagat gtgcagtaac aggtgaggag cttatcttat ctgaaatgca ttgtcatcat
     2701 attatccctt atcatgaaag caaaagtgat agctatgaaa acctagtgat tgttactgag
     2761 gaggttcatc gggtaataca cgctacacaa agtgaaacga ttgaggaact tctaaaatat
     2821 ctaaaattaa atccaaaaca aaaagaaaaa ctcaatgagt tgagattaaa agttggtaac
     2881 gaagaaatat cttaataaat atttgtagga cgggaaaaca gaatgtcttt tatagacgag
     2941 ggaacgccgt atgcggtgaa agtcgcacgt acggtgtgga ctgggggaaa agacggagat
     3001 aatatcaaac tcttacctat cagtatcgat taatccagat tttattgaaa cggtaaatta
     3061 tgtcacaaac tttcaacgag aaatgcgtaa agtagaagca atgactgttt tagctacaca
     3121 atccccacaa gaaatggtgc cagaaaatat gtcttctgat aacttctcga aactgaagaa
     3181 agtctttgaa ttttcttcta cgaagatctt tatgcgtatg gatgaatcta ttttacgtca
     3241 tatagaagga ttagtgggta aatcaatgac gaactcagaa ttagaatcca ttcctcaaca
     3301 aaatcaagga gacgctgtga tcaattttgg ctcaaaagaa accattcgtg ttcattttag
     3361 tccgaacaaa cgtcaattaa aattgtttga tggaggaaaa taatggaaaa ccaaaatgaa
     3421 agtttaatca agcagtatgt taagcgtcgt gcaaagcggc gcttattttt gtggttgttt
     3481 ggtacttctg caggtttgat tactattttg atcactgtgt tcgtgaccct atttctaata
     3541 cttgcggcgg gctcgattga taattcggat tcagattcaa gcagtggtgg cgaagctttt
     3601 acaggagaat attcggaagg cttaccgatt tataaagaaa tcaaaggaag aggccctttt
     3661 tctgatgaga ttgcgcaata tgccgtaggt gcagcagtga aatataaatt attaccaagt
     3721 gtgatccttt cgcaatacgg ttacgaatca gcgtttggta catcggcgtc cgcaagaaat
     3781 gatctcaact attttgggat tacttggttt gatggttgtc tgtttcctaa aggaactgca
     3841 cgaggaattg gtggcattga aggtggctgg tacatgaagt ttcccaactc aaaagctgca
     3901 ttttcctatt acggctttat ggtagccaca caatccaatt ttaatgcttg tgtaggaaat
     3961 aaaagccctg gcgcaagctt attgatctta ggacgaggcg gttatgccgc tgcaggaatt
     4021 acggaagata gtccgtatta tacaggttgt atgtcaatta tcacttctaa taaattaacc
     4081 gaatatgatg aattcgccat caaacattgg ggtgaaggtg gcaataacaa cggcacgatt
     4141 actggtgaat ggacgaatcc attccctggc agcagtttag ataaaagttc cttcagcggt
     4201 ggtcaattat ttggaacgaa tccaggcggt gaattccgtc cgaacggctt ccatgatgga
     4261 ttagattttg gttcagttga tcatccagga agtgagattc atgcggttca tggcggaaaa
     4321 gtcgtgtacg ttggcaatcc tggtatttca ggtttgggcg cgtgtgtgat cgtgattaat
     4381 tacgatggct tgaatatggt gtatcaagaa tttgcaaata gtacaggaaa ttctcgagtg
     4441 aaagtaggcg atcaagtgaa agttggtcaa gtaattggga tacgagatac agcacacttg
     4501 catttaggat ttactcgaat ggattggcgt caagcacaag gacatgcatt cattgatgat
     4561 ggtacatgga tcgatccgtt accatttttg aatagcagta aaaaatagat caggagaaaa
     4621 aatatggaaa ataaaacgtt aaaaatcgtc ttaacagctg caattagcgt tagtttaatc
     4681 ggcaatattg cgttgttttg gcagctgaaa gaggaacaag cagcaaatac ctataaaatt
     4741 gaagaagtgg ctaaaaacgc gtctgagaag ctcaaaaaaa attcctctga ggcacaggcg
     4801 aagatcgaca agttaaatca aaccatcaat gagaaaaacc aagaaatcga tcagctgaag
     4861 caacaagatg gcacaaaagc aaaagaggaa gtaactgaag cacaaagaaa gacggcagaa
     4921 gagttcggtc aattggccat tgataaatca ttaagcagaa atgaattaac ggaaaaacta
     4981 aaagatgtcg caacccaaga agtgatcgac aaattaagtc ctacagacga tgatcaccaa
     5041 catgatgatt acggaagtta ctcctttaca ttaggtgacg tgcaaactta cgctcaaaca
     5101 agcagtgtaa aagaggaaca aaattttgtc gtatttgttg attatacaat cggcaatccg
     5161 caattcaaag atgtcaaacc acaaaaaata aaaggtggat taactgtcac tgaaaaacaa
     5221 gtagatggtc aatggaaagt catagacttt agttatttca ctcgttagga ggaagaaaat
     5281 gagtaagaaa aaaggagaaa gacaacgttt caaaaaacga aaaagttatc ttagatggct
     5341 gggaatcttt atgattctcg gctttttgat tcttgctagt ccgatttata cgaatcagaa
     5401 ggtagatata ccagatgagg taagcacgaa cgccttttta aacacgaaag agctgacaat
     5461 ggtttcaaaa gaaaaaggag cgaaccagca attagttttt gaatttgcga tcgatgatga
     5521 agatcaaagc ttgttaaaag aactggctaa tcttaattat cgcgtagaag taaagacagc
     5581 taaaggggat tatcaagcaa tacgagccaa agtgattaag gtgtctgatg attattttgc
     5641 agtgaagcta acgcatgtac cagaagaata tatcgccatg cgtttaacca ttattcctga
     5701 aaaaattgat ccaaaagtgg atatgcaaga accacaagat ctgatttatt acgtgcacga
     5761 agataaggtt aaagatcaag tgaaagatga agattatgaa caacacgcga tcaattacaa
     5821 agtgaaagga tacaagaaag aacaaaaagc agctcaaaaa caaatggaat ctttccaagc
     5881 aaccattgat ttgaatgaag aattagtgaa gaagctaaaa gatcaattgc cttatcaagt
     5941 cgcagatgat caggaaaata ctgaaaacaa gattaatagc taccagcaag aaattgaaac
     6001 atcgaaaacg caactgaaag atcaagaaga gatcattcaa aaacttcaag aaaaaattga
     6061 tcgtatgaca aaagaaaaga tttagaagga caggtggagt gaaaaaatga agcgaacaaa
     6121 cttggctgac aaagatactt tcgctgagca gaaagtattg attaaagcct atctcaaagt
     6181 tgtaaaagct aaagaaatat gtcgagaagt gaatttatct aacacaacaa tatctgagtt
     6241 gaagaatggt cgaaagaatt tagatacttt aaaattcaga tcatttgaag ctctatatgt
     6301 agctgctaaa aaatatttta cagctgataa caaataaaaa acaggagtat tttatgtgaa
     6361 aaaagtatat aaaaaatgct tatgaatcag ctatatcacc ttaaccattt gttaatgaga
     6421 tgggagaaaa cattaaccac gattctaacg caaacatcaa gcacataaaa catttaacac
     6481 tcctcctttc tggctgaaga tttcaaccaa acaggaagac agcgtatcaa ttatagcata
     6541 cactttttct taaattcatt tttcatatga caaaatattt ccttctaatc gacaaagtta
     6601 gaaggatttt ttattgtcta aatacacaaa taaccttaat ttttaaagag cataaggaaa
     6661 cgtgtaccca ctttcaaaat aaagtgggta gataggctgt gcctatcacg tttctgaaaa
     6721 aaataaatga ccccaaaatt ttcaatttat gtgtaggttt atgggtagca aaaatatgaa
     6781 tgtgggcagc aaaaagttca tttgtgggta gtaaaattca aatgtgtgta gcaatgtgtg
     6841 tagctacaca cattgctaca cacgctataa catatagtga aaaggagata tttatggaag
     6901 taaaaataag agatattgat gaaaaaacga ttcaaagaat tgaccgaaga tgtattgaat
     6961 taagtgaacg caccgggact aaatggagcc gaaatcgata cctaaaagtt ttgattgaaa
     7021 atgattttga ccatgaactt atggatcata gaaaagatca atttgatcgg ttgttagaaa
     7081 aatttgtgga tattcaaact tataatacga aaattttaga agaatatatt gcaacaaata
     7141 atcaattaat cgccttgtta attgaataat aaaaatagta ttgtgaattt ataaaaggag
     7201 gaaatcaatt ttggcaaaag caacaagaaa acatgtatat ctttacgata tgcatatcga
     7261 agtacttgat gaaataattt ctactcatga agatatatct aattatagtg aagcagtcag
     7321 acatttgtgt atgatgtatg atccaaaaat cgaagaaaaa ataaatccaa ttcaaattaa
     7381 attgaatgca atgggaaaag aaatttctat attaaccgaa atggtttcag agtttgcgga
     7441 tcttcatttg aaagatacag gaatactaat tggtacaaat tcaactgtct atcaagaagc
     7501 aaaagagcgt gtggaaggga aaataaaagc gaatcaaacg aaaaagtatt ctcctaagat
     7561 caagaaacca ataaatgaat ctgttcatgc cagagtagac ccgtttgatc caacaaagtt
     7621 tttaaaaaga taaaaagtag aaggggaaca tgatgaataa atcgcctgca gtcattctca
     7681 cttgtcaatt taccttgccc aataaaaaat ctttttcaac atacattgat tatatgacaa
     7741 gagaaaaagc gctggaagaa aaggaacgac gcacgccgga cgaagaacag gaactgcaac
     7801 gaatcaagaa tgctttagag gatttttata ttcctgaagg agaaactttt tcggagagta
     7861 agacagataa agaattcagt gaaacgtcga atgaagctca atcgttgatg gaacatggaa
     7921 tcaattttga caagttagag gaacaagatt ttaccaaata tctttcttat atgacccgtc
     7981 actatgcgtt agaacaaaag aaagaactga cgcaaaggga acaaaaagaa taccaacggt
     8041 tgaaccaagc aatgaaaaaa tatcaaacag agccacataa aaaagcttca ggaaatcttc
     8101 ctggagtttt ttctatggct tcagacgaag tgaaaggaag tgatctgaag gagatcaaac
     8161 aaatcttcca aagagggcaa caaaaaggct caatcattta tcaagatgtt gtctctcacg
     8221 acaattcgta tcttgaaaaa atgggcttgt acgatcccaa aacagatacc ttagatgaag
     8281 aaggattaaa agcagctgga agaaaaatga tggagacatt attcgagaaa gaacaattga
     8341 atgaaacagg ttactggatg gcaacgattc accgtaacac taagcatatc catattcatt
     8401 ttgcagttgt tgaaaaagaa aatacgcgta aaccttacac ggaggttgaa aatggtgtga
     8461 gttatatcgt accgaaaggt aagagaagac aagcaacatt agacgcaatg aagaccaatt
     8521 atgtacatga gttagaacgt ttttcttatg aaaaggatcg aatgattggt atggagaaac
     8581 gaaatttatt gacgcggaaa agtgatttgc gtaacacctt aacaaaagtg gtaaaagagc
     8641 cagcgcgtta cgatcgacac gcaatgaact tattaaatga agtatataaa accctacctg
     8701 acaaacgttc ggaatggcat tatggggatg aaaaacgaac caaactttca ccatacacaa
     8761 gagagaaact cgatgagtta accaaatatg tgttaacaaa agaacctgaa tatcaagaat
     8821 atatacagat ttcaaaatca ttgaaagaag aagcaaaaag tctttatggg gaaagcaaga
     8881 gagaatcaaa ggatgcagaa aaaaatgctc tctttgattt gaagaagcgc acaggaaatg
     8941 ccattctaac agaactgaag aaacaggata gtcaaataaa acctttaata gaaagtatgg
     9001 atcagatgca atctatttac aatgaacgat cctttcgaac gcttaaacag ttaccaacga
     9061 atgaatacaa atatagttac gaagaattca tgaagcgcag gaaacaattc caacaaagag
     9121 ttgtcacgca acggagtttg cgtcaattaa atcgaacgat taatgcccat gaagaaaaat
     9181 accacgcaag taaagcctac gaagagcaac aacgaagaat tcaaatggaa caagaaagac
     9241 agtaaagaca gtaggaggaa tagcaatgaa acaatattta gatcaatgga aagttataga
     9301 aggatcatta agagaagaac gaatcgaaca acttcccgat tgtttagaaa aagagcattt
     9361 gtttcagata agagaaatgt tgagaaacga acagtttgat ccaaatcaat ttttagtcgt
     9421 tgagtactca gctactggtg tgtactgttg taatcatgtg aagggtgaaa aatattttat
     9481 cattcaagaa tatgagggca agttagcgcc ttattatact acttgggaaa tgaatgaaga
     9541 ggggatcaat aacttcccgt gtaaaagcat tgaagagtct atttcactca cagaatgtta
     9601 gttgttaagt gaataaaaga agtaaaagag tcctgaacgt aattgtccag gactcttttt
     9661 ttcaatgaat tgttttccgc caattcaatg agtggtgcga tttgcgacta cattatatca
     9721 aaagaaagag aagggaggaa gaagaaatgg cttattcaac gattggagtt gttgttgaaa
     9781 aaagcagaga caatctcgtt tttgtgacag aaattcaaac gggcagagct tttgtcgtca
     9841 cagacaaagc ggcaaaagcg tatcaaagtg gcgatatttt aacgttaaat ctgactacga
     9901 agacgttcgt cgatgcggca gaagattatc cattt
//
LOCUS       DAKCAA010000083         9466 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000083 DAKCAA010000000
VERSION     DAKCAA010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.084"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..3443)
                     /gene="nifJ"
                     /locus_tag="OUE31_002401"
     CDS             complement(<1..3443)
                     /gene="nifJ"
                     /locus_tag="OUE31_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HCU0223375.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLHHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLNLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LA"
     gene            3642..4163
                     /locus_tag="OUE31_002402"
     CDS             3642..4163
                     /locus_tag="OUE31_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCU0223376.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(4862..5419)
                     /locus_tag="OUE31_002403"
     CDS             complement(4862..5419)
                     /locus_tag="OUE31_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223377.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(5598..5921)
                     /locus_tag="OUE31_002404"
                     /pseudo
     CDS             complement(5598..5921)
                     /locus_tag="OUE31_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5902..7028)
                     /locus_tag="OUE31_002405"
     CDS             complement(join(5902..6800,6800..7028))
                     /locus_tag="OUE31_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCU0223378.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNTLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(7108..7461)
                     /locus_tag="OUE31_002406"
                     /pseudo
     CDS             complement(7108..7461)
                     /locus_tag="OUE31_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7574..7831)
                     /locus_tag="OUE31_002407"
     CDS             complement(7574..7831)
                     /locus_tag="OUE31_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223379.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(8428..8706)
                     /locus_tag="OUE31_002408"
     CDS             complement(8428..8706)
                     /locus_tag="OUE31_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223380.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(8740..8991)
                     /locus_tag="OUE31_002409"
     CDS             complement(8740..8991)
                     /locus_tag="OUE31_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223381.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         2758 a         1969 c         1530 g         3209 t
ORIGIN      
        1 gcaagatttg gatttgcgtt atctagcgag gaaaagcgaa cttgtttcct catgaaatca
       61 ggcatagcag agaaatcagg ttttttgtag tccaaagtca ttgggttctt gtttttttcg
      121 accattgtag ggttatatcg atataatgac caataaccag aagaaacagc ttcttttgct
      181 tctttaagcg attctttcat tccgccaagc aagccatgtg tgatacaagg cgtataggca
      241 ataatcagag aaggaccagg atacttttct gcttcttcaa atgccttgat cgtttgcatt
      301 tgattggcac ctgaagcaat ttgcgccaca taaacatttc catatgtcat cgccatcatt
      361 cctagatctt tctttgaagc atactttcca ctagccgaaa atttagcgat tgccgaagct
      421 ggtgttgctt ttgaggtttg accgccagta ttggaataga cttcgttatc caaaacaagg
      481 atattcacgt ctgctccgct ggcaagtaca tgatcgatcc cgccaaaacc aatgtcgtaa
      541 gcccatccgt ctccaccaat catccattgg ctgtttttta cgaatagatc ctttctcttg
      601 tatatatcct ccagttcagg gaaaattgat cgttcgcttt cgatcgcagc ttgcagtttt
      661 gctgctcttt gctgcgttcc ttcactctca aacatgtgta ctaaccagtc ttccatcaat
      721 tctcgtagtt cttctgatac ttttggcaat acttctttga ttgaacttgc caaagcctcg
      781 cgacgagtct gtgccgctag aagcatacca taaccaaatt cagcattatc ttccaataaa
      841 gaatttgacc atgcaggccc ttgaccacat tcattggtcg tataaggaga agcaggagaa
      901 gcaccgcccc aaatagaaga acagcctgtc gcattcgcga tcatcattcg atcaccgaac
      961 atttgtgtca ataattttac ataaggtgtt tcgccacagc ctgagcaagc gcccgagaat
     1021 tcaagaagcg gttgattgaa ttgtgtagac aagacagtat tctttccttt gactggattt
     1081 gctttttgtc ttaatgtcat tgcaaaagcc caattcacag cttgttcttt ctgttcttca
     1141 taaggcttca tcactaaagc tttttctttt gcgggacaag cctctacaca cagaccacaa
     1201 cctgtacagt cttccactga aacttggata cggtatttta cgccgtctgc gcctcgcatt
     1261 tctctcacga taaatccttc tggcgcttct tccatttcct cttcatctgc taaaaatgga
     1321 cggatggcag catgaggaca aacaaaggca cattcattac acatcgtaca gcgatcacta
     1381 atccactcag gtacttctaa agcgacgccc cgcttttcca tagaagccgt tcctaaaggc
     1441 atttcgccag ttgtcattcc atttgctaca agtgtaccaa cagagagttg atttccttcc
     1501 tgtgcattca ctggttcaag tatttcttgt atataaccag tgttcctttt attgattttt
     1561 tcaggcatct ccaacgttct ccaatggtct gggatcgcga cttgatgaag cagttcggtc
     1621 gtccgatcga ttgcttgtat gtttttttct acgatagcca ttgatttatg tccatagctt
     1681 ttcagggctt cttcttttag cagcggaagc acctcatcaa aaggaatgat gtcagctaat
     1741 ttaaaaaaag ccgtttccat tgccgtattg atccggcgtc ccaaaccgac ttcttgggcc
     1801 aatctcatgg cattgatcgt atagaatcta atgttatttt cagccaagta acgttttaat
     1861 tttaagggca gatgcgtttc taattgttcg tcgctccaaa gagtattcaa taaaaaaatg
     1921 ccacctggct tcaatccttt gaccaagtca tagctatgca ggtaagctgg tgtgtgacag
     1981 gcaacaaggt ccgcatgctc gacaagatac gctgaacgta tcggcgtatc tccaaaacga
     2041 agatgagaga cagtcagacc gccagatttt ttcgaatcat aataaaaata gccttgcgca
     2101 tatttatcgg tgtgatctcc aataatcttg atagctgatt tatttgctcc aactgttccg
     2161 tcagatccaa atccccaaaa cttggcctgg aatgtttgcg gttctgtcaa attcagactt
     2221 tcctttggtt ccaaagattg ataagtcaca tcatccacga tccctatggt aaaccgtttt
     2281 ttgcgtatgc ttgggtcttt tttcaattca tcaaaaactg ctgagatttg gtcgggagtc
     2341 acatctttag accccaatcc gtagcgacca ccaataacag ccgggcgaag ttcagaatca
     2401 tataacgcac tttgaacgtc taataagaga ggttctccac ctgcccctgg ttctttactt
     2461 cgatcaagaa cagcaattgt ttttactgta tgatgcaact tttgcacgaa tgtttccact
     2521 ggaaaaggac gataaagatg gatattcaaa aaacctgttt tccgtccgtt tgcattcaag
     2581 taatcaatcg tttgttcaat cgtctgtgca actgatccca tagaaacaat gacttcttcc
     2641 gcatcgtctg ctccgtaata agtcaccaag tcataagaag ttcctcgtaa tcggttgatc
     2701 tctttcatat atttttgaac gatttcaggt aatttatcat aataggggtt gatcgtttcc
     2761 cgttgttgaa aatggatgtc tggattctgg ttcgtaccac taacagtcgg atgattggga
     2821 ttcatccctc gtttacgaaa tgaagctaat ttctcctgat tgatcagagg agctaattct
     2881 tcatattcca aaacttcgat tttttgaatc tcgtgactcg tacggaatcc atcaaagaaa
     2941 ttcaaaaaag ggacttctcc ttcaatagaa gcaagatggg caacaggtgc taaatccatc
     3001 acttcttgta cactgctttc agctaacata gcaaatcctg tttgtcttgc agccatcacg
     3061 tctccgtgat ctccgaaaat attcaacgca tttgtcgtca ctgcccgact agcaacgtgg
     3121 aaaacacttg gcagtagttc cccagcaatc ttgtacatat tcggtatcat caaaagcagc
     3181 ccttgtgaag cggtatatgt agttgtcagt gcaccagttt tcaatgatcc atggaccaca
     3241 ccagctgctc ctgcttcgga ttgcatttct actactttta ctggttgacc gaatacgttt
     3301 tcttttcctg ctgctgacca ttgatctact aattcagcca tggtcgaact gggtgttatt
     3361 ggatatattg cagcaatctc ggtaaatgca taagaaatat atgcggctgc cgtattgcca
     3421 tccattgttt tcatttttcg catgattcat catccttgtt catattctct cttattatct
     3481 gttccattat aacgtaaaac atgccatttt tttcttttat ttataaaaat attttacatg
     3541 tatctatttg aattggtcat ctaattttta gacaaacagt ctaaatcgtt gccttttttt
     3601 gtcagacatg tataaactat aagcgaaaga ggtgttttaa catggatata tcagtgattg
     3661 atgcaacgaa aacaaataca caaaaaggaa tcctttatgg ttcatcgaat gctcctaaaa
     3721 aaatggtcga attcatcaac ttagcttgtc cgtattgccg acaatggttt gaagaatctt
     3781 atgagctatt agaagaagca gtccaaagcg ggcaattgca gcgagtgatc aaattgttcg
     3841 ataaagaaaa agaaagctta cagcgaggga acgtgatgca ccggtatctc acaatcagcg
     3901 atggccaaaa agcgatcaaa gagatcaaac aaatattcga tactcaagac gagtggaaac
     3961 atctttctct ccaagaagta gcggattttg cagtagataa actaaagctg acagaacaaa
     4021 aagacgaaca gctgagccaa gctgtcatca acgaagctga gcaagcacat attcgatttg
     4081 ttccaactgt catcttgggt aaagaaatct ttgatgaatc tatttcaata gaggaattaa
     4141 aagaattgat ccaaacaaaa taaaaaaata aggagcgtgg gacaaaagta aagaacactt
     4201 ttgtctcacg ctctaaacac gtataaacgg cggaagcaga agcaactcct tcttatttct
     4261 tggagttaaa cgcttctgtc ccagcctcct tattccgaat aaatggtgtc caaaagcttg
     4321 catctgccag attatctcat ttcttatgac aagctaagca aattatctcc accaaataat
     4381 ttattcatat ttttgacttg cgcatactaa ctaattctta aattttcata caaaatttct
     4441 caatttccct taacgagtaa tatttatgta cggtgattct cactagtatc ccaatcactt
     4501 tttaagttat cccgatttca attctacttc aaaaatagtt gcttttatgt atgctgttag
     4561 ttgattagat ggtcatttgt tgagctaggt cgtttatttt aaacaagttg tttctttagc
     4621 ttatacctat ctcgtctacc aaacgcaaga tggcaaacac aaatgcatac gcatctgtat
     4681 ttgccacttt gattcgtata aagctaacaa ctattaactc ctctcagcta atagttgctc
     4741 tcttttttat tcagattcat ttttgctgat cacagcctag tatttcaatg gttttgaaca
     4801 ctaaaccaaa ttgttccatt acaacattca ctggctgatg aaatggatta gtagatttcg
     4861 attattcaaa gcgattttct attggtggat cgtgttccca actaataaga cggattccaa
     4921 acctatcgta cagatcttct aaaccactta taaattttgc acctatttca ggtgttttat
     4981 tgcgtggata ttctattgtt acgccattaa atggatacca attaggatta ggctctcttt
     5041 ttttctgtac atctcccata gaatagttag cactttctgg gacataatat attcttcgac
     5101 catcctctaa ttcatctaat aagatatttc gtgatcgtct atcacttgct aaatgtagac
     5161 gccacgtgcg ataccatgcc atgctacctg catctgcaga aaatccatca aataatgcaa
     5221 caattgtatc ttctatcaca atcctttccc catctacttc atattctaat ctaaaatcaa
     5281 actcccctcg ggtaatttct ggtcttggtg gcttaggacc caatattatt ctacttaaaa
     5341 ccgcattcgt tcccagatga aacacagcta taacaacaat aatgattaat attttgtttc
     5401 tatttgataa atttctcatt attcgcacat cacctctaca ttctcacata ttagttcgta
     5461 atactccttt aatatcaaaa tatctactgg tcgtaataat attcgctatg aattcctact
     5521 actcgtataa gaaaggccaa atcatcagct tttacttgct gatgatttgg cttgtttcta
     5581 tttatcgtaa ttgttttcta atcaccaaaa ttgttaacaa tcggttcaga tatttcccag
     5641 ttgattaagg taattccgta ttgtgtcaaa acttcttgcg cttctccgaa attaagtaca
     5701 gttcttatgt atccactttc tcctaatata aagtctacct ctcttttaaa accttcctcg
     5761 agatttctaa gggctatatg tggttttaat gacattgatt gtacattttc ccccatataa
     5821 tattgcgcac ttcctcgact aaaatagatt cctagatcgt ggatttgagt caatatcttg
     5881 gacacatttt agtagagacg gttaagccat tttttctttt gctaattctt caaattcctg
     5941 tggggttaga tagtgaatcg agctatggat tcgatttcgg ttataaaatc cttcaatgta
     6001 gctaaatagc gctcgatttg cttcttcaaa atctgagtag ctagtcgtgt agacttcttc
     6061 ttttttcaat gaggcatgga aagattcgat tccagcatta tcataaggtg ttccttttct
     6121 actataagaa tgccttattt tgttggtttt aagccattgt tccacttctc ttgctgtgta
     6181 ttggctgccc aagtcagtgt gtagaatcat tccttctgga atgtgataat gtatttttgc
     6241 tttattcaat gtttgaatga cacaatccac agtcattcgt tttgaaaatg tataactaat
     6301 aatttttttc gtgtgtaaat ccatgattga agataagtaa caccaaccat ttttcttagt
     6361 aggaatgtac gtaatgtcag ctgcccattt ctcacagatc gtttcagtag aaaagtcctg
     6421 atttaagaga ttctcttttg aaatgatcgg tttattagac ctttgaggtc tatatttttt
     6481 aactacaatc gaccttaaat ttaattgttt cattagcttt tggacatgtt taagagatac
     6541 tgaaatccct tcttttaata aaacttgatg gatctttgtg gcaccatagc gttgtttatt
     6601 cgtaaaaaaa attgttgaaa tcttcttttt caacgtatta tttctgattt ctgtagctgt
     6661 caacggttta ttcttataaa aataatagac acttctaggg atttctaata accgacacaa
     6721 caaagaaaca gtgtaatcct tacaccattt ttcaataaat tgaacaagcg aatttaggtt
     6781 ttccgagaga atatggctgc ggcttttttt aagatttcaa gttcctcatt taaacgagca
     6841 ttttcttttc tcagttcagc tacttctttt ccagtcagtc ctgtggactg atcaggtaaa
     6901 tataaattct tccatttgta aatcgttgct tcagataagc catattcttt cgctaaccct
     6961 cgaacagaac gtccagtttg attcagttca acaatcattt gtttaaaatt ttcttcatat
     7021 cgggtcataa aaattcatcc tctcgtagat aagtttaatt tattcttgtc tctacgaaaa
     7081 gctgtctaag atttgatact aacaccaatc gtccccaaaa ggtagatctt ctctaccact
     7141 agctaatcta cttctccatc ttcgttctct tttcatagaa cctgcgctga actcacaccc
     7201 gttaaactca gctatgacag tatcttcaat tatgttaatc tgtccatcta gttcgtattc
     7261 aatcctaaat ggaaattctc cataggtgat ttccggttcg ggtattttag gtgagattaa
     7321 tgcaaagaaa ggaaatatta agcttggcaa catcaaaaaa actcctccta tgatcacaat
     7381 tcccgatgta atccaaaata taatttgtac aattctcatt gatccattgt attccatttt
     7441 attcccccta ttactattca tatccgccta tctatatcga tcttccaatg cagagataat
     7501 tgcttccata ccttgatttt ttactgagtt acctatgcga gatatcattc tccactaagg
     7561 tgcatcatat tgtctatcta acatgattaa ttctccaata ggtgtatact cctccaaaaa
     7621 caacatttaa tgcatctccc tcgacaacat aagctaccat gtttgctgta tatgtgtttg
     7681 agtctaattc ataagcagat aaatttactg tcgctggatt aaatataatc gcattcgtat
     7741 ttatagctac tgaatttgct gcttcagcac caccttttga atgtccgatc attgtgattt
     7801 caatagtagg atttacgtgg acagccctca ccgtttaccc tgaccattat agaaatcgct
     7861 tacttttttg aactacgcaa caaaggatac aatgctccta acttcactgt ctccattttt
     7921 gtccactaag gaatataaaa aataggcatt aattcattta attcggtcac aacacgttac
     7981 cttttaaatc attatactgt atctcataca ttattatcaa taaactatta taaaaatgca
     8041 aaaaatgctt tatcaatcta ttttgtaatt ggtcataata tcattgaaat cataccctgt
     8101 atcgattttt cctatgaatc tcgtctattt gtgattgacg aaaaagaggc aagacagaca
     8161 ctggaatggt aattttaccc actattttgc tccaactatt tgtaatcgta cccacttttg
     8221 aaataccgag atgatcattt taattgatat gctgattccc aagcaaaacc ccaagaaatt
     8281 aaatgctcta tcgcatctag cttcttgggt tttgcttata taaattccaa catttaaatt
     8341 ttttatgctg ttcggtctca gaaatgccgt ttttgcttat atcacaatat caagatgtca
     8401 aattattcgt gttgccgatg actttgatta atttttttca aattgtttat taagactaat
     8461 gctgtctttt tgcagatacc aatgttcgaa ctttttaaca ttatcatatg atcctgcaag
     8521 ttttaacttc ttaccattag atgttatcaa agttataatt aaccttgcct ttttcccatt
     8581 aggatctttt attttatgaa ttttctgcag gtaatctctc ctaatggcag ctatttttac
     8641 ctcatcagtg ctgataaacc attgatcatc cacatacata ctgcctgtta tgttgtgttt
     8701 ttccatttct tccgagaacg aaaagtttaa ggctcgttct tacttccaaa gttgaatgag
     8761 tccatggatt ggacttagtg tgagaattga gaacaacaat aagaatccat atcctcccgc
     8821 aaacatccct aaggctatac tgtctctcca tccataagta ggattagaag agaaaagagt
     8881 caccgtttgt aataatatga aaaggaataa tccagcacaa acaccaaaga taacaactcc
     8941 aaacattgaa tttttataca atgaccattt atttataggc ttttctttca ttttacttcc
     9001 ccctactgtt ctgttcacac ggaatgaatt caaagttcat aagccctcct ctttgaacat
     9061 atgaatacga cttgctaact atactttaaa aaagcttgtt ttaagcggtt ataggcgagt
     9121 tgtaatctct attcatctca ttagcaaata acttgccgaa aagtctactg aaattaaagc
     9181 agatagtgga agaattattt agccaggata gacactattt gtgaaacaca tgtctttact
     9241 tttgaaattc tatgatgaaa agccttggaa tacagtagct cttaattggt aatacttttt
     9301 ccattataaa taacctcttt tcattttata tttatcccct ctaaaaataa tatctaatct
     9361 aatattttaa acttatattt ccctcgctgt gctaatagag cattactaaa taaatagaaa
     9421 ctagaaaaaa gcattacgcc tgccagaata aaccaattat ttgtat
//
LOCUS       DAKCAA010000084         9291 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000084 DAKCAA010000000
VERSION     DAKCAA010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.085"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(921..1307)
                     /locus_tag="OUE31_002410"
     CDS             complement(921..1307)
                     /locus_tag="OUE31_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223382.1"
                     /translation="MIDKQITNILQSYKKQQIFKIEDFLLSEIDEDNLQETIDFVVSD
                     DVSKKINFSDELYDGNEYEGVFLEGNQYLLSSSEGKVMIIDMLSEAHGVNIKDTRVQF
                     DEEKFIKLITNKKEILNWIKNYKVDK"
     gene            complement(1324..2391)
                     /locus_tag="OUE31_002411"
     CDS             complement(1324..2391)
                     /locus_tag="OUE31_002411"
                     /inference="COORDINATES: protein motif:HMM:NF013630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCU0223383.1"
                     /translation="MAKPSTPATYKVKAGDSVWGICEKYGLSISKFVQWNKIKNNTIH
                     PGQKLTVKQPVSSGKPTTKVPASTNPVTHKVSYGESLWLISSKYGVTVDELRKQNGIK
                     GDLIHPGQVLVVKKGMTTSHSTPVGKSGTSYTVKAGDSVWLIANRYGVSMDDLVKWNK
                     IKNYTIHPGQVLTIQTIVSTPAKPAITTTPKVKAKPAITTTPKAESKSGVTTTPKVDE
                     KPVITTIPKVKEQPVVTTVPKTESEVLVEKASGDGSRLDINIKNFEIKNKHLNSSTAK
                     RARKFNVSSAEEANKIVQDALKNGKLVEAIPNGVGSQGQNSFSSIIDTGKVIGTKGET
                     HIKIVYDELKNVWTTYPVPKP"
     gene            complement(2913..3425)
                     /locus_tag="OUE31_002412"
     CDS             complement(2913..3425)
                     /locus_tag="OUE31_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003771789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223384.1"
                     /translation="MKIKSYEDKLVKDDIEVDYYVPITVSFPENDDKYNLGEFYYYRF
                     VNEYESFVEIKINSVTQKIVEVVFTSINDIEDSNLFIGEYAEKNPVIQTDIFDENSII
                     TKESGFKISREHKKLCFKLDKEKMDSVVKMSNHVSLFLNEDSEIIGLEFSSFSDNEWA
                     ELNESIKSTT"
     gene            complement(3444..6407)
                     /locus_tag="OUE31_002413"
     CDS             complement(3444..6407)
                     /locus_tag="OUE31_002413"
                     /inference="COORDINATES: protein motif:HMM:NF013630.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016617326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCU0223385.1"
                     /translation="MLKKVLRFGVCISIWLVTSSTFVPSMIAVADSVAIQETIASDSE
                     GEEKLTERSDDASDGQTEKVEVQKTETTQTTVSSSSDESSDLTQSSEETAPEEVDEST
                     EESSDPQEQTISHEEETKEAVDSSTIDFEGTRSSESFGKHTSPSIDKPNEKIAEPVSS
                     NEGAVVSRRSRRDLSAVSSNHPEEEPVVAFDEKAFDAAIDQYIDHATEEELGLVINSS
                     NEKELADALEYLLLNQLDESFGVEELDELKKFLTADEIERLENESSLETFEQLLTQYY
                     NDREQKLEEGAAFSDFFLASTDEEIDRMLEVKDEQALEQVISEISASRNSQTSGKRNK
                     RFLVIPLLVKGAMLVIGAGVAAYSSHQFYKTMEAQRAEKKRMVERWRYHEQQAQKRHQ
                     AAQQARAKAVARAKLQAAARAKAQATQRARAQAAAKARKQAQNWAKQQAAARARAQAA
                     ASARRKSNASYVPPVTRPKPVIKAQPKVPAKPVAKPVTKPTSPAKPKPTTTPKNTMHQ
                     VRAGESVWSISHKYGISMNDFIKWNKIKNNLIHPGQQVIVKQPASTSKPVSKPATKSS
                     TPATYKVKAGDSVWGICEKYGLSVSKFVQWNKIKNNTIHPGQVMHLQEPKPASKPAPK
                     TSPTTNTTYTVKAGDSVWLIANMHGISMNDLVKWNKIKNNTIHPGQKLTVKQPVSSGK
                     TTTKVPASTNPVTHKVSYGEPLWLISSKYGVTVDELRKQNGIKGDLIHPGQVLVVKKG
                     MTTSHSTPAGKSGTSYTVKAGDSVWLIANRYDVSMDDLVKWNKIKNYTIHPGQVLTIQ
                     TIVSTPAKPAITTTPKVESKPAITTTPKVESKPGVTTTPKVDEKPVITTLPKVKEQPV
                     VTTVPKTESEVLVEKASGSTGTVWDDIKGTQPPREGTTIPKSFEIIVNGEKLWVNPNG
                     TKHMVEYSTRNLSHGQKLTEQQLLRSFQGAVEQATSTGIKFETKIIIDNWELIFSPAR
                     EAGQLPVIKHAVYLP"
     gene            complement(6653..7120)
                     /locus_tag="OUE31_002414"
     CDS             complement(6653..7120)
                     /locus_tag="OUE31_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223386.1"
                     /translation="MKKSLIVLIVGLSIFGSVLFIGNSLFSNKDVTEQSPASTTEEVS
                     PELLLETDVLDTKKPETIPSENELYQGDLSFEYADPEKPYVLTIRFIDKANHEYVGPD
                     KKPLKREKELILGKAKGVVHVVVKANRSMLTHIQKLKDIQVSMTLNERNEKTE"
     gene            complement(7142..7294)
                     /locus_tag="OUE31_002415"
     CDS             complement(7142..7294)
                     /locus_tag="OUE31_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002392643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223387.1"
                     /translation="MKKKGIPYSPKPRNAFERGLFKYFEGERDQEEKEKNQKKKSSQE
                     KENIEK"
     gene            7795..8136
                     /locus_tag="OUE31_002416"
     CDS             7795..8136
                     /locus_tag="OUE31_002416"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223388.1"
                     /translation="MKANTPYKVGDIFYSSWGYEQTNVTFWQIIKLTKKTAWFRPIKK
                     QTVKNYTSMSGETMPIPNEFIDYPLARTKDSIVRKRINPALYPNELYGNRSWDTFYRY
                     DNQPVYESSYY"
     gene            8347..8622
                     /locus_tag="OUE31_002417"
     CDS             8347..8622
                     /locus_tag="OUE31_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223389.1"
                     /translation="MPIVDSYDRNTNNYLGSFEQTDENILNYVAGLSPFESVRLVEHT
                     TDTLILTTIGYFFDQVSDQQWLQQILPKLIAKQTGKSTIEAVKIFFY"
     gene            8678..9226
                     /locus_tag="OUE31_002418"
     CDS             8678..9226
                     /locus_tag="OUE31_002418"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223390.1"
                     /translation="MSILQPFGEPIERTEFIQHYMKLFVQVIKHTHQIDEFYSKEIEY
                     LLAEKQKIALLYDYFVEMYDRAPDYFYLSDTLTTNFLAKEHLFASHTKNLMCVEHFVN
                     TYLHLLKIQKICTFEAFQTDYLFILDREAYHAKLAFEKQNQAIEGYPELRIQNNSFLQ
                     QRLLKQLINGFHQRNKAYQKDQ"
BASE COUNT         2659 a         1815 c         1486 g         3331 t
ORIGIN      
        1 gacttccttt tttgtatgga ttttttcatt tacacaaaat attttacact ctcaagaaaa
       61 tactacaact cagatatttt ttacaacgat ttacagaaaa ataacctctt taaatataaa
      121 aagtatgggt tactgattac ttataaatct ttacggtcta gtttcgcaac aattcctttc
      181 tttctaaaaa atatactcac attttttctt tcttggactt cttttttgat tcttctcttt
      241 taactcttgc cccttttctc cttcaaaata tttatgcttc ctctttcaaa aacgttttta
      301 ggttttggac gataaggagt gacttttttt catataaaca cctcattcaa ctgttcgatc
      361 cattttatat catcacatta taaaaataac aaatatatta aattttttta tcaaaatcat
      421 cttaaccttt tggaagatta cagtacgctt tctttttatt cccaaacttt ttttgttgct
      481 cactttcgta tagccaatct aagcgatcat cgacgacggt gcttttacaa cgaatggtta
      541 gttttgggcg ctgacttatc tactgtttta tagtagatta tcttctgaga attctcatat
      601 taaacttttg tatacctcta aagtggatat aaagctttca actgtacctc aagaacgcct
      661 cgaaagcttc aacaactatt tcaacaataa attgtctttc tttgattaaa atttatatat
      721 cattcaaata attaactatt aaaattaagc gataaaatag aaaaagaaac gatacaacta
      781 aatcgtttct ttttcaactt cagcttatac tattctatac atagataact ttttattagc
      841 aacttgatta gtgagtgtat gcttactatt caaggctttg ctattcgacg ccaatcgaat
      901 agtaaagtgc cttttttatt ttatttatcc actttataat ttttaatcca attaagaatt
      961 tcttttttgt tcgtgattag tttgataaat ttttcttcat caaattgaac tcgagtatct
     1021 tttatattaa caccatgagc ctcacttaac atatcaatta tcattacttt tccttctgag
     1081 ctagatagta aatattgatt accttctaaa aatacacctt cgtactcgtt cccatcatat
     1141 aattcatcac taaagttaat tttcttacta acatcatcag aaactacaaa atctattgtt
     1201 tcttgtaaat tatcttcatc aatttctgaa agtaaaaagt cctctatttt aaatatttgt
     1261 tgttttttat acgattgcaa aatattcgtt atttgtttat caatcacttt gcttacctcc
     1321 tatttaaggt tttgggacag gataggtagt ccacacattt tttaattcat cataaactat
     1381 ttttatatgt gtttcccctt tggttccaat aactttccct gtatcaataa tactagaaaa
     1441 agaattttgt ccttggctcc ctactccatt tggtatagct tctacaagtt ttccattttt
     1501 taatgcgtct tgaactattt tattagcttc ttcggctgaa gaaacattaa actttctagc
     1561 ccgtttagca gttgaactat tcaaatgttt attcttgatt tcaaaatttt taatattaat
     1621 atccaatcta cttccatccc cactggcttt ctcaaccaat acttctgatt cagtcttagg
     1681 aacggttgtg accacaggtt gttcttttac tttcggtatt gttgtaatta ctggtttctc
     1741 gtccactttt ggtgtggtag tcactccaga ttttgattcc gcttttggtg tcgtggtaat
     1801 cgccggtttt gcttttactt ttggtgttgt cgtgatcgca ggttttgctg gtgtagaaac
     1861 aattgtttga atcgttaaga cttgacccgg atggatcgta taatttttga tcttgttcca
     1921 tttcactaga tcatccatgc tcacgccgta tcgattagcg atcaaccaaa cagaatcccc
     1981 tgcttttacg gtatagctgg ttccgctttt tcctacagga gttgaatgac tcgtggtcat
     2041 accttttttg acgactaata cttggccggg gtgaatcaaa tcacctttga tgccattctg
     2101 tttgcgtaat tcatcgacgg tcacaccata tttactacta atcagccata aagattcacc
     2161 ataagagact ttgtgggtga ctggatttgt agaagcgggt acttttgtcg ttggtttccc
     2221 tgatgaaaca ggctgtttga ctgtcaactt ttggccagga tggatcgtat tattcttgat
     2281 cttattccat tggacaaatt ttgaaatgga taacccatac ttctcacaaa tcccccaaac
     2341 tgagtctcct gcttttactt tgtacgtagc tggcgtactt ggttttgcca ctggtttgga
     2401 cgttggtttt atagtagatt atcttctgga aattctcaaa ttaacctttt acatgcctct
     2461 aaagtggata taaaattttc aactgaagaa gcaaaggtca ctaatagtaa atatgaacac
     2521 tatttttgaa tctggaaaag agaaaattaa tatgacaaat gactaaatag aagttgtgaa
     2581 ggtacttgtt ataaaacaat ttctaaaagg agcggaaggc aatgagaaaa atgattcttc
     2641 tgatccgtaa aacactataa agaaagtcaa tagatcatta gtctctccta atattgctat
     2701 tgactttctt tattgggcat gtgcttttga tagtgcccga ggaactcaca aaatacctag
     2761 taccttggat tatccctcga accttttcag cataacatgc ccaccgttta ttttagcatt
     2821 tgaatttgtt ctttcaaaat tcttttgttt catcctcaga atctagcaaa atagctgttg
     2881 aaaatcctat cttcttctca tttaaaatta aatcaagtgg tagattttat actttcattg
     2941 agttctgccc attcattatc tgaaaagcta gaaaactcta aaccaataat ctcactgtct
     3001 tcatttagaa ataaagatac atgattagac atctttacaa cagaatccat cttttcttta
     3061 tctaatttaa aacataattt tttgtgttct ctagatattt taaacccaga ttctttagtt
     3121 ataatcgaat tttcatcaaa aatatctgtt tggatcactg gatttttttc tgcatactct
     3181 ccaataaata aattggaatc ttcaatatca ttgatggatg tgaatactac ttctacaatt
     3241 ttctgtgtaa cagaattgat tttaatctca acaaatgatt catattcatt aacgaatcta
     3301 taataataaa attctcctag gttatactta tcatcatttt ctggaaatga tactgtgatt
     3361 gggacataat agtcaacttc tatatcatct ttgactaatt tatcctcata acttttaatt
     3421 ttcataattt gctcctttca tagttatggt agatatacag catgtttaat aactggtaat
     3481 tgtcctgctt ctctagctgg actaaatatt aattcccaat tatctattat tattttagtt
     3541 tcaaatttta tccctgtaga agtagcttgt tctacagcac cttgaaaact ccttaacaat
     3601 tgttgttcgg taagtttttg tccatgagat agatttcgag ttgaatattc taccatgtgc
     3661 ttggttccat ttggatttac ccacaacttt tccccattaa caattatttc aaacgattta
     3721 ggaatagtag ttccttctct tggaggttgt gtacctttaa tatcatccca gactgtacct
     3781 gtagacccac tggctttctc aactaatact tctgattcag tcttaggaac ggttgtgacc
     3841 acaggttgtt cttttacttt cggtaatgtt gtaattactg gtttctcgtc cacttttggt
     3901 gtggtagtca ctccaggttt ggattccact tttggtgtcg tggtaatcgc tggtttggat
     3961 tctacttttg gtgttgtcgt aatcgcaggt tttgctggtg tagaaacaat tgtttggatc
     4021 gttaagactt gacccggatg gatcgtataa tttttgatct tgttccattt cactagatca
     4081 tccatgctca cgtcgtatcg attggcgatc aaccaaacag aatcccctgc ttttacggta
     4141 tagctggttc cgctttttcc tgcaggagtt gaatgactcg tggtcatacc ttttttgacg
     4201 actaatactt ggccggggtg aatcaaatca cctttgatgc cattctgttt gcgtaattca
     4261 tcgacggtca caccatattt actactaatc agccataaag gttcaccata agagactttg
     4321 tgggtgactg gatttgtaga ggcgggtact tttgtcgttg ttttccctga tgaaacaggc
     4381 tgtttgactg tcaacttttg gcccggatgg atcgtattat tcttgatctt attccacttc
     4441 accagatcat tcatactgat cccatgcata ttagcgatca accagaccga atctcctgct
     4501 tttaccgtat acgtcgtatt agtcgtagga gaagtttttg gtgctggttt tgatgccggt
     4561 ttcggttctt gtaaatgcat cacttgtcct ggatgaatgg tattattttt gatcttattc
     4621 cattggacaa attttgaaac ggataaccca tacttctcac agatccccca aaccgaatcc
     4681 cctgctttta ctttgtaagt ggctggcgta cttgattttg tcgcaggttt ggacactggc
     4741 tttgatgtac ttgctggttg tttgacgatg acttgctggc caggatggat cagattattt
     4801 ttgattttgt tccatttgat gaagtcattc atactgatgc catacttatg cgaaatagac
     4861 caaacagatt ctcctgcacg tacttgatgc atcgtatttt tgggggtcgt cgttggcttc
     4921 ggtttcgctg gagaagttgg tttcgttact ggtttggcta ctggttttgc aggtactttg
     4981 ggttgggctt tgattactgg tttcggacga gttaccggag gaacatagga cgcatttgac
     5041 tttcttcgtg cacttgcggc cgcctgtgca cgagctcgag cggcggcttg ttgtttagcc
     5101 caattttgtg cttgttttct cgcttttgct gcggcttggg cacgagctcg ttgtgtggct
     5161 tgcgcttttg cacgggctgc tgcttgtaat ttggcacggg caacggcttt ggcgcgggct
     5221 tgttgtgcgg cttgatgccg cttttgtgct tgttgttcat ggtaacgcca gcgttcgacc
     5281 attcgtttct tttccgcacg ttgtgcttcc atcgtcttat agaactgatg gcttgaataa
     5341 gcagctaccc ctgccccgat taccaacatc gctcctttga caagcaatgg aatgactaag
     5401 aagcgcttgt ttcgctttcc acttgtttga ctattccgag aagcactgat ttcagaaatc
     5461 acttgttcca atgcttgttc atcttttacc tctaacatcc gatcgatttc ctcatcggta
     5521 cttgctagaa agaagtcact aaatgctgct ccttcttcca atttctgttc tcgatcatta
     5581 tagtattgcg taagcagttg ttcaaatgtc tctaacgacg attcattttc caatcgttca
     5641 atctcatctg ccgtgaggaa cttctttagt tcatcgagtt cttctacacc aaaggactca
     5701 tccaattgat tcaacaagag atattctaaa gcatcggcca attctttttc attgcttgaa
     5761 tttatgacta accctaattc ttcttctgtt gcatgatcaa tgtattgatc gattgcggca
     5821 tcaaaggctt tttcatcaaa agcgaccacc ggttcctctt ctgggtgatt tgaagaaacc
     5881 gcagaaagat ctcggcggct tcgccgtgaa acaactgctc cttcatttga agagactggt
     5941 tcggctattt tttcgttagg tttatcaata cttggagagg tatgtttacc gaatgattca
     6001 gaagatcgtg ttccttcaaa atcaatcgtt gatgaatcaa ctgcttcctt cgtttcttct
     6061 tcatgagaaa tcgtttgttc ctgaggatcc gaagactctt cggtagactc atcgacttct
     6121 tctggcgcag tttcttcgct ggactgggta agatcacttg attcatctga actgctcgat
     6181 accgtcgttt gagtagtttc tgttttctgt acttcaacct tttcagtttg tccatctgac
     6241 gcatcgtccg agcgttctgt aagcttctct tccccctcgc tatcagatgc gatcgtttct
     6301 tgtatcgcca ccgaatcggc cactgcaatc atacttggca caaaagtgga agatgttacc
     6361 aaccatatac ttatacatac cccaaatcgt aacacttttt tcaacatatt tttcttcctt
     6421 tcttcattta cacctaatta aaataacgat cattatcata ctgaaaattg tagaaacaaa
     6481 tttaaatagg tgtttaaaga aataatatca tcatttttaa tgatgataaa taacagggaa
     6541 gaaaaaaatg acctttcatt tttgtaatat gatcaagcaa ctataaagat ggaacaaaat
     6601 aaataaaccg ataaaagtag aacagatatt cccaaaacat gtctgatttc cgtcattccg
     6661 ttttctcatt tctctcattt aatgtcatgg acacttggat atcttttaac ttctgaatat
     6721 gggttaacat cgatctattg gcttttacaa ctacgtgtac gacaccttta gcttttccta
     6781 gaatcaattc tttctctctt ttcaatggct ttttatcagg ccctacatat tcatgattcg
     6841 ctttatctat aaaccgaatc gttagtacat acggcttttc cggatccgca tattcaaatg
     6901 aaagatctcc ttgatagagc tcgttttccg aaggaattgt ctcaggtttc tttgtatcaa
     6961 gaacatccgt ctctaataat agctctggag atacctcttc cgttgtgcta gcaggggatt
     7021 gttccgtaac atctttgtta gaaaacaacg agtttccaat aaataaaaca cttccaaata
     7081 tacttaatcc aacaatcaat actattaaac tttttttcat acttctctat tttttcacct
     7141 actatttttc tatattttct ttttcttgac tagacttctt tttttgattc ttctcttttt
     7201 cttcctgatc tctttcgcct tcaaaatatt taaataaccc cctttcaaaa gcatttctag
     7261 gtttcggaga ataaggaatg ccttttttct tcatacaaac acctctttta actatttgat
     7321 ctattttata ccaccacatt atcaaaataa caaatgtatt aaaaggaatt tcttattaaa
     7381 accatcttga ccttttggga gatttcagtg cgatttcttt ttattcccat acttttttcg
     7441 ttggtcgctt tcgtataccc aatctaagcg atcatcggca gtagtgcttt tacaacgaat
     7501 ggtaggacaa aacaaggggc ggaaaaactt ttttgatcat ttcataaaaa actttttcct
     7561 acagcattcc cttgttttct cttaccacac gttgtgacct aaaagcacgc cgacgaacgc
     7621 ttagctatac gaaaatgacc aaccaaaaca aaaaagtgag gtgaatggaa acaaaaagaa
     7681 attgaaatct cccaaaaggt cacccgcctc ggagacaact tgctgccgaa aatggttggt
     7741 tgattcggct aagtatcaaa taaggcaaat caaatattat tggaggaata gatcatgaaa
     7801 gcaaatacac catacaaagt aggagacatt ttttatagta gttggggcta tgaacaaacc
     7861 aacgttactt tttggcaaat tattaaatta accaaaaaaa cagcatggtt tcgacccatc
     7921 aaaaagcaaa ctgtaaaaaa ctatacttct atgagtggag aaactatgcc aataccaaat
     7981 gaatttatcg attatccgct tgcacgaacc aaagacagca ttgttagaaa acgaattaat
     8041 ccagccttat atcccaatga attatacggt aatcgcagtt gggatacatt ttaccgctat
     8101 gataatcaac cggtttatga aagcagttat tactaagagg gtatttccct cttagtcaac
     8161 gttacaaaaa taaaaggagc aagaacaatg aaaccaataa ctctatatga aatcttaggt
     8221 gaagaacggt ctgacaattt accaacaacg cataaattaa gagttcttgc ttctaaatct
     8281 atcggtaaaa aatgataact gagtatttct aatcaaggag agattgcaat gctaagaaca
     8341 aatgctattc ctatcgttga ttcttacgat cggaatacca ataactattt aggatctttt
     8401 gaacaaacag atgaaaatat tttgaactat gttgctgggt taagtccttt tgaatctgta
     8461 cgtttagttg aacatacaac agatacactc attttaacaa caatcggcta cttcttcgat
     8521 caggtatctg accaacaatg gttacaacag attttaccta aacttatcgc aaaacaaact
     8581 ggaaaaagca ccatcgaagc agtcaaaata tttttttact aaatacatgt attcattctc
     8641 aagggatttt ttcccttgag tgaaaggaga aagaatgatg tccatacttc aaccctttgg
     8701 tgaaccaatc gaacgaacag aattcattca acactatatg aaattatttg ttcaagttat
     8761 taaacacact catcaaattg atgaatttta ttccaaagaa atagagtatc ttctagcaga
     8821 aaagcaaaaa attgctttac tttatgacta ttttgtcgaa atgtatgatc gcgcaccaga
     8881 ttacttttat ttatctgata cacttactac taacttttta gctaaagaac atctttttgc
     8941 ctcacacaca aaaaacctta tgtgtgtaga acactttgtc aatacctatc ttcatctgtt
     9001 aaaaattcaa aaaatctgta catttgaagc atttcaaaca gattatctat ttattttaga
     9061 tcgtgaagca tatcatgcaa aactagcatt tgaaaagcaa aatcaagcca ttgaaggcta
     9121 tccagaatta cgcatccaaa acaattcttt tttacaacaa cgattgttga aacagctaat
     9181 aaatggattc catcaacgaa ataaagccta tcaaaaagat caataactgg ttctttttga
     9241 taggtttttt ccatcaaaaa cagaaacttc tttttttaat tgtttgatta c
//
LOCUS       DAKCAA010000085         9017 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000085 DAKCAA010000000
VERSION     DAKCAA010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.086"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            136..309
                     /locus_tag="OUE31_002419"
     CDS             136..309
                     /locus_tag="OUE31_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223391.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            949..1422
                     /locus_tag="OUE31_002420"
     CDS             949..1422
                     /locus_tag="OUE31_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HCU0223392.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="OUE31_002421"
     CDS             1431..1658
                     /locus_tag="OUE31_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0223393.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2010..2381
                     /locus_tag="OUE31_002422"
     CDS             2010..2381
                     /locus_tag="OUE31_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223394.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2637..2879)
                     /locus_tag="OUE31_002423"
     CDS             complement(2637..2879)
                     /locus_tag="OUE31_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCU0223395.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(2911..3813)
                     /locus_tag="OUE31_002424"
     CDS             complement(2911..3813)
                     /locus_tag="OUE31_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCU0223396.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(3826..4014)
                     /locus_tag="OUE31_002425"
     CDS             complement(3826..4014)
                     /locus_tag="OUE31_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCU0223397.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4028..4591)
                     /gene="amaP"
                     /locus_tag="OUE31_002426"
     CDS             complement(4028..4591)
                     /gene="amaP"
                     /locus_tag="OUE31_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCU0223398.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4629..5522)
                     /locus_tag="OUE31_002427"
     CDS             complement(4629..5522)
                     /locus_tag="OUE31_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCU0223399.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5600..6523)
                     /locus_tag="OUE31_002428"
     CDS             complement(5600..6523)
                     /locus_tag="OUE31_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCU0223400.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6572..6922)
                     /locus_tag="OUE31_002429"
     CDS             complement(6572..6922)
                     /locus_tag="OUE31_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCU0223401.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(6955..7857)
                     /locus_tag="OUE31_002430"
     CDS             complement(6955..7857)
                     /locus_tag="OUE31_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCU0223402.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(7850..8707)
                     /locus_tag="OUE31_002431"
     CDS             complement(7850..8707)
                     /locus_tag="OUE31_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCU0223403.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
BASE COUNT         2525 a         1713 c         1489 g         3290 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaaaa atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagctg aggaatagta tgccatttat tgtttacttt tttctttcat
     2041 tactcgtgat ctatattcca ttaccaacat ttttcctgct cgtcaatcgt ctagcagagc
     2101 aacatgatac gattgctgct cttacgaaac tttgtttact tctatttgtt tgtctagatt
     2161 actttacgag ctattattgg ctaaaacaga caagagtaaa aaagagatat tatttcttcc
     2221 ttgtcttttt caatctcttt gagtttctga tccattgctt tttacttcat cagtatcata
     2281 cgatccattt gtggatcatc tgggttttca aagtggtcgt attattttgt atgttcacct
     2341 ttcctatctc aagaaaattt agggaggcat tgttttatta aagaagcttc tctgtatcaa
     2401 taaagacaca tttaaggaaa aacttttaaa aatctaattg ggaatttgcc cgcataaata
     2461 agaggctgtg acaaaagtct tgtcacagcc tcttattccg tataaacagt gttcaaaagc
     2521 ttgcatcttc gataatatgc ccaaccaaat gaaaaatatg agaagctatt tttgtttggc
     2581 tgttcttatt acttgatgaa gaacagcttt ttcacgacct ctttttaaaa gtctttttac
     2641 agttttcgag caaagaatga tacgattagt actaaaatga tggcaccaat caatgatggc
     2701 acgattgcca ttcctgcaat acttggtccc caagaaccta ataatgcttg accaagtgct
     2761 gatccaacta aacctgctac gacatttgca ataatcccca tcgaagaacc tttattcgtg
     2821 attgctcctg caattgctcc gataattcct ccgacgataa gtgaccaaat aaatcccatg
     2881 tttcgttcct cctaatgttt tacttcctta ttactgaacc cgtggttctg tattttcttt
     2941 tactttttgt gcgccgcttc cagctgctga ttttacttta tctgtttgat tcgaagcaaa
     3001 ttcaccggtt tttttcgctg cgtcagttac tttgtcttgc accgtttctt gatctttttc
     3061 aaattcttct tttgttttga tgtccactac gttagcgttg acttcgatca cttctaaatg
     3121 tgtcatattt tttacttctt tgccgattac ttcttgcatt tcttcaaaga ttttttcgat
     3181 atctttgcca tattccacaa tgacatccat atcaactgct acttgttttt taccgacttc
     3241 tgtttcgatc ccagccgtta cattatctgt attcacaagt tttcctgcca cattagagaa
     3301 gaaaccaccg tttgcagata ataaaccgtc tacttgttca attgcgattc cgatgatttt
     3361 ttgcacaact ttatcttcat aattcagctc accgcgcatt gaatcttcct gttcagaatc
     3421 atgctttcct tggttatttg tatgatcaga accaagtttt ccttgtccgt ttgtgtggtc
     3481 agaactaagt ttttcttgtg ctttcgcatg gtcagaagga tgtttttgct cttccacagg
     3541 tttagaagga tcgattgcat catgttgttc tggaacttta gattctggag ttcctggatg
     3601 atgaggtgca tgcttttctg catcatgttt cttctcttct actccttgtt gaacgttagg
     3661 gactactgga tctggatgtg cagatactgg tgctgttttg ttcttttcat cgttcacacc
     3721 atttgattgg tttggtgtcg ttgggtctgg atgtgcagac actggttttt ggttgttcat
     3781 tttattgtta ttatttttgt tattgttatt catggatgtt tcctcctaag atttaaaata
     3841 gtgatctaag attttcgttt gtttcagata aaaaccgata gcgacgccga tcgctgccat
     3901 gatcaagatc aataaggtct tgaaaaagcc cacggtgatc cataaaacgg ctaatatcaa
     3961 tccaagtacc ccaaagatga tagggagctt gtatgtcgaa aatagttctt tcatttttgg
     4021 tcccccccta ttctactcgt ttgcggtcat tgcttcgttt agctggttct tcaaagcctg
     4081 tgtatttcac cgatactttc actggctctt ttgttcccaa tatgtgttgt acttcatttt
     4141 cgatttcttt catcaatgtt cctgttttac caatgagtgc tgaagttcgt ttcaactccc
     4201 cttttacatt gacggcgatc ttgtttttcg ttgctttgac atttactttt ggtgaatgga
     4261 tgaattcatc ttcatgcaag tgagaacgaa ccattccttc aattgctttt ttatccaacg
     4321 tcaactcccc atcaccatgt ttcagtagaa agtttccgat tgtttttgga taaaacagga
     4381 aaacaagtaa cgtgataatt gtcaaaatag caaatgcaac ggcaagccaa aatacatatt
     4441 gttgcacgta tgaattagtg atggaaaaga atcgaaactt ctctagctga aaaggcaatg
     4501 gataggttgc acttaatagt atcgcaaaca aaagcacaga tagcaaaagt aatgttccga
     4561 tcactccgat cgtttttaca cctttattca ttttcgcacc tcctcatagg ggtgaaacga
     4621 tcaacttctt ataagttgat cgcttctcca ccagttactc cgtaaatttg ggctgtaaca
     4681 taacttgctt tattcgatgc taagaaaaca taaactggtg ctaattctcc tggctgacct
     4741 gcacgttcta gtaaactttg ctgaccaaat tcagggatcg aatcagaagg ttgtccttcg
     4801 tctagttgta atggtgtcca gattggacca ggtgctacac catttacacg gattccttta
     4861 ggtgcaagct gttttgctaa accgatcgta aagttagcga ttgaagcttt tgttgctgcg
     4921 taatctaata aatgttcgct tggattgaat gcttgaacag aagttgttgt tacgattgct
     4981 cctcctgctg ggatatgcgg aacagcttct ttcactaaag caaacatagc gatgatgttt
     5041 atcataaatg tgtctttgac ttgctcaagt ggtaactcag caatagactg acaagaaatt
     5101 tgctgtcctg cgtttagtac catcgtatct agcccgccaa gttcactcac ggctttatct
     5161 atgatttctt taggtgcttg ttcgtcacga agatcaaaag gtagtaagac aatcttacgt
     5221 cctgcatctt tcacgtattt tgctacttcc tctgcatctt tttcttctcc tgggaagaat
     5281 tgaagagcga tatctgcccc ttctctagca aatgcaatcg ctgctgcacg accgatccct
     5341 gaatctccac cagtgattag tacacggcgg ttttctagtt gattattgcc ttcataggat
     5401 tcttctccac aatcaggaac aggaatcata ttctgctgta aagctggtgt atcctgatct
     5461 tgtttaggaa atttctccgt atggtacaag tttcgcgggt cgattaattt tggttctgtc
     5521 attgctgtat tcctcctagt ttttaaattg tattgccaaa acaaatttct ttgtttgata
     5581 cctgttttaa atagattctt taatttgtat aatctttccg gtataaatgg taacctaaaa
     5641 ctactgctgc tatcaaagag ccaaagacta cgagtataaa gcctagagca gaacttttac
     5701 ccggtaatcc tcctgtattc attccccaaa tccctgcgaa caacgccgga acggaaatga
     5761 ttaatgcagc tgaatctaga tatttcatga tatgatttag attattgtcc atcatcccgt
     5821 tgaatagatc accaatactc tctaataaat ctcgatagat ctcgatcatt ttttctgttt
     5881 gtcgctgtct caaatggaca tcatagagta gctgttcatc gtctaaacgt ttgatgaaag
     5941 tttcagaatt ccataattga tccattgttt cccgttgatc tcttaaggta tgatcgatat
     6001 atacgatgtc tctttcaaga tctgcctgtt tatacagttc ttcattttcc gttgttttac
     6061 gagctgcttt atccaaagcg tcaattcgct ttttcatctc tcttagttct ttcacgtaat
     6121 gggtgtaaat atctaataat gtatacgtga tgatcttttc aaacgagttt aaatgatttc
     6181 catgctttgt cagcagccga tccacaaatt cggtttttct atcgatacaa gtaatcaaga
     6241 gattatcgga aagtacaaaa gatattggcg ttaatttttt ttcgatacga ttatctgact
     6301 gatctagatt aatcactacc aaagaaaatg gatgctctag tttcgtctca taaaggcgct
     6361 ccatccgaga aacttcttcc ggatattcgg ttcctacgaa aatatcatca ggaagctcga
     6421 attcttcgat tgcttgctca atctcttcgg gctttgcact atcaagtacg agccaattat
     6481 attttttttc atctgtttct attacattct tttcttcatc cacaaagtag tatctcaatg
     6541 tatacctcct ttttggactt tctcgaaact attagctgaa gaagcagttc tttaatttga
     6601 tattataatc gagtactgcg atttcatttt ctaatgaaaa gctgtcaagc tgtttgttga
     6661 agtccatgtt caatcgttta ccgaaataat tttgctctaa tttagatgta tagatgtcca
     6721 ataatggatg ctcgatttta gtcgcatatt ctccaaattc cgaaacaaaa ggaatgattt
     6781 gaaaaaagct gccttttgca aaagcacctt tgtcccttag aaatggatcg gaatcattga
     6841 taagcgcgag tgcgattttt gtattttccc caaccttttc aattaacgtc tctactgcat
     6901 ttttagacat tgtaatttcc attcctactc cccctcttca gttgttgtct tctattattt
     6961 aacaactaca tctgtttttg gttgaacttt tgcatatttt ggatatttag ggaatttagc
     7021 tacacaacgg aaagccgtca tccctgcata tttttcgtaa tatttcttcg ttggcccttc
     7081 aaaatccttg ctccacggtt tcacatgtcc tgaaaaatgg ataatgtaag gattgttgcg
     7141 agtttcttcg tattcacgtt cacctgctgc tgttggatgt ttttttgctt ttgccatgat
     7201 atagccttgt gcattccaac gcggatgaag tggtaaccaa cggtcatgta agatagcatt
     7261 taatgcatct tggtcatgga atcgtaattt ttctggatta tgttcgatga aatctaatac
     7321 tttttgcgta atattttcat ctaaccattt tttcacattg atcagcatca aacctgagtt
     7381 gaaataacgc attgatttag ctgaaatttt cattttttcc agtcgttgat ggaacccagc
     7441 gtcttcaaca gctgctacga ttgaatcacc gaagtcaaga cgccataatt tagagatatc
     7501 ttgtaaagcg atcatgtcgc aatccatata taagatacgt tcaacttctg tgccgcggaa
     7561 caattccgga atcgcaatac gataataagc tgtttctgga atacgatcgc tgattaccac
     7621 atttgtaaag aattctttat tgattttcaa gaattccaca tctgagttca ttcgtgcgtt
     7681 tttcactgag aagcgtaaaa gctgtttact ttcaaaatcg atatcatcgt caatcacata
     7741 gaaccgaaca aatttagacg ggttgcaatt atctaatact gagacaaata atgcagctaa
     7801 atgtggtacg aattttgtgt tacaacttgc gactactgct atttcttttt tattcattga
     7861 tctcgcctac tttcgttaga gtactgtgtg ctaatttttt taagtataaa ttggtatacg
     7921 gatgatcttt caacgtattc caaggtttat catgtcctgt aaagtgaacg atcgaaggtt
     7981 tttcatttcc ttctttatac tgacgttcat atttttcatt tggtgctgga tgacgttcaa
     8041 aaatcagcga agtctgcatg ttccattttg gatgaagttg ttcccaatct tcataaagta
     8101 cagcattcaa agcatcttgg tcgtgataga tgattcgatc gccattttca ctgaggtaat
     8161 ggatagtttt ttctgtaatt tcttttttat tccattgatc aatgtcaatc accatcactc
     8221 ctgaattgaa gtacaagtca tcggaatcga ttcctaatct ttccaaagct ttcacttggc
     8281 ctggatcgat aatagcgccg attgtttttc catttaacgg ctcatcatat agttttacga
     8341 tatcgtctag tactaacaca tctgaatcta agtaaaggac tttcttataa tcctctttag
     8401 ctaataagtt tggtaaagaa attcttaagt aagcggtagt tgtgatatgg tcactgacta
     8461 ggaagtcttc gtagatatct ttttccactg tcaggaattg gatacttgca ttacttgaat
     8521 atttatttac cgtttcttcc aatccttctt tactatattc tgatagacca tcgtcaatca
     8581 cataaaattt tatgcgtctt gttttattgc aattttctaa tgcagttgcg atcatcacgc
     8641 tcaagtaagg agcataattt tcgtctgaag cagttaccac aggaactacg ccgtatctct
     8701 tctccatcaa aatcactcct ttttctaatc tttttctaac ctgttctaca tctagaatat
     8761 tcctcatttg gttttaaagc aaaatatatg ctttgttttc attgaatatt ttaaaatttt
     8821 tttatcacaa aacgcatcgg taagcgctaa ctattcgttt ttcatggctt tttattcaaa
     8881 ggtattgacc aaaaactact atatatagcc acctttttct taagaatgtt ttttgaaaaa
     8941 attcataatg acaaagcaag ttagtttcat ttttttaaat tctcatttaa tcttaaggta
     9001 acaggaaaat agatatg
//
LOCUS       DAKCAA010000086         8913 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000086 DAKCAA010000000
VERSION     DAKCAA010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8913
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.087"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(777..2408)
                     /locus_tag="OUE31_002432"
     CDS             complement(777..2408)
                     /locus_tag="OUE31_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HCU0223404.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(2422..4095)
                     /locus_tag="OUE31_002433"
     CDS             complement(2422..4095)
                     /locus_tag="OUE31_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HCU0223405.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            complement(4108..4425)
                     /locus_tag="OUE31_002434"
     CDS             complement(4108..4425)
                     /locus_tag="OUE31_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCU0223406.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            complement(4450..5850)
                     /gene="lacG"
                     /locus_tag="OUE31_002435"
     CDS             complement(4450..5850)
                     /gene="lacG"
                     /locus_tag="OUE31_002435"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCU0223407.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            6087..6872
                     /locus_tag="OUE31_002436"
     CDS             6087..6872
                     /locus_tag="OUE31_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCU0223408.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            6875..7567
                     /locus_tag="OUE31_002437"
     CDS             6875..7567
                     /locus_tag="OUE31_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCU0223409.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(7841..8212)
                     /locus_tag="OUE31_002438"
     CDS             complement(7841..8212)
                     /locus_tag="OUE31_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HCU0223410.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(8612..8842)
                     /locus_tag="OUE31_002439"
     CDS             complement(8612..8842)
                     /locus_tag="OUE31_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223411.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
BASE COUNT         2759 a         1927 c         1491 g         2736 t
ORIGIN      
        1 attataacaa ttgggttaaa aagaaaatag atagtattct acctcatatt tatttgaaag
       61 taatatataa aagacgttca aattcgaacg cctctcgtta accaaatatt ggattcagaa
      121 tctagttttc atatataaac agagtatgat taggtgcaaa aattgcactt ttattgcact
      181 tttattttta tttatagtgt tttactgttc tgtatattgt tttaactccc ttgatagtat
      241 cgcattctgt tttatacact ttacgttgaa aacagagtgg gaataaagag ccaacataat
      301 atggaggggg aatccctata aatcaacatt cttcaatagc taaaatgctt gattttcatt
      361 aaaaataaga tggttcccta ccaaaagaga ctataatata agttaatttg tttcattctt
      421 atcataaaaa gaagttctcg aaaaacgaac tgttttccga gaactttttt ctatccatct
      481 aagtgctcaa atcatattca cgacggaatt ctaaggttac cctttcttaa acaaacttta
      541 tgttatctgc acaacttttt gcaatttttt cattgcttct tacgaaatcg ttgaactctc
      601 tttagcataa tacaaagtgt agatgaagtc tggtgcttta ctcgttttgg taaaaatgac
      661 tggaaatcgt ttctggttat ttttggcaaa ggcgaggtgc aggttcgatt cctgccttct
      721 acgctaacga tgtggctgaa gggaacctcc gatcttgaat cgaaacgatc cgcagtctat
      781 tgtttcacca atgaaacaaa atcaacgttc gtccaagcat ttcctgaagc cttgctataa
      841 accccaattt cacaaacacc tgttgtaatt ggaatgtctt tgattgtaat ttttgtccat
      901 tcacttgttt taacaaccgc agtatttagt tccgctccac cataattttt gatatataac
      961 tgattagtat caaactctcc cccagacatt acataggcac tcaatgtgta agttcctttg
     1021 cttatgccac taacattttg ataagctgat gcctcgtatg cttgatcctg ccaaaaagtt
     1081 agtttgtagt ccccaaaaaa agtgcccgct tccgttttga tcgtaccctt agcggttcct
     1141 tgttgaaacc aggtttgcca attggaagga ctggtcgttg gtccatcgct ttcgaaactt
     1201 gcatttttaa ctagatttat ttgcgcccct gcttgtttaa acgcacgcaa gcttggcaag
     1261 gcgtttccag caaaatcaaa catcgcttgg ttgtcccatt cgtttcccat agtggattga
     1321 acactgagat aattcatacc tgcttgtgtt gcccaactca catttccgtt gtaccaaaga
     1381 ggttcccaat agaagaagcc cgccccgcga ttattcggta ctgcctgaat ccgatcggca
     1441 agatccagca aatactctgc ttgtcctgtc ggtgttggtt catatccccc cgcagctgct
     1501 tcggcttcac caaaagcatt tggcatagta tcggcattcg ctgttgtatg cccataagct
     1561 gtttcaacta cgatcacttc tttaccatac cgttggctga tcgcattcat attggtttga
     1621 agttcattca ttgaaccgtg ccaatacgga taatacgaca ctccaattaa atcaaatgac
     1681 acacctcgac tcgtgatttc atcaaaccac caagtaaatg ctcctgtatc gccaccatca
     1741 gctaagtgga gcattactgg agttgtttta ggttgagtgt ctcgaacagc ttggatacca
     1801 gacttcaaaa aagcagccaa tcgatcaaat tctcccccgc cttctcccca agacttgcca
     1861 taaggccaga gcattccgct attcagttca ttgccgatct gaaccatatc aggataaacg
     1921 tccagctgct tcatttccga cagaacgttc tttgtatagt cgtacaatgc cgtattcatt
     1981 tcttcaaagg tcagaccttg ccatgcttta ggaagattct gtttcccagg atcaacccaa
     2041 aaatcactgt agtgaaaatc cagcagcacc ttaagtccca gattttttgc tcgttttgca
     2101 aggtcaatcg tcgtttccag atcatttgtc cctgctccat aactttctcc attactatta
     2161 taaggatcct gccacaaacg cagtcgaaca tagttgacac cattattttt taaaatctct
     2221 aaggcatctt ttgaaatatc gtcttcataa tattttgcac cagatttttc catatctgac
     2281 aggatcgaaa tatctgctcc gcgaataaat tcgctggcag atgcttcaac agtttttgaa
     2341 acagccccca aagcccctaa cacagctgca aataaaacag ctttacgcaa ccaaattccc
     2401 attttcatta tggctcctcc tttattgaaa ttggttcaga ataaactgaa cagctttttc
     2461 aggatctctc gttaatccga tatattctgc tccttttgtc gcaaccagct tgattcctaa
     2521 gcgatcggtg tcttctttga tatcatcata gtaagaattg acttgcggtg ctaagaccac
     2581 catatcaaaa tcctgcagca tttcgtaatg agaaccataa gcacccgcca ttgcactgat
     2641 cggtgctttc gattcagatg cacctttttt taaagcatta gctaacatcg cacttgtccc
     2701 tgcgccagca caaagtacca acacattgat ttctttattt gcatcgctga taacttgact
     2761 cgctgccaca ggtacttcct cacgtacatc ggcagaagca ccttcctcgg ttgcgatcac
     2821 ctctgctttt tgtgcttctt tctctactaa gacagcatcg tatgctttgc aaaatggtag
     2881 atagatcagg aagtcaacga cgattagaac cgctgctaga acaaaagcta agatacccat
     2941 gcccgttcct agaaccaaac cgatcggtgc tggagttgcc caaggcaaaa cgtacataaa
     3001 gctgttcatg cccaatacat cgacaaaaaa cttgaacagg caaacgttta caacaggtgt
     3061 taacaaaaat ggaataaaaa aataagggtt caaaatcatg ggtgccgcaa atagcaatgg
     3121 ttcgttgaca gcgaaactta ctggaataaa ggaagctttc ccaactgcct tcaactgctt
     3181 agacttagca aagagtagga agataaaagg aacaaccaat gttgccccag ttcctcccat
     3241 agttcctaca aaattcccta aacccaccgt cagtacttta gaagcttgtt caccggaatt
     3301 gaacaattgc agattggttt ccacattggc atagataatt gccgcaattg ccggctccac
     3361 gatcgacggt ccatgaacac cgacaaacca aaacagcgcc atcgctcccc agataatagc
     3421 gattcctaag tacccgtcag ctgctgtaaa tagcggctgc agcaccgtaa tgattgcttc
     3481 tgcaaatgag atttggaaga tttgtcgaat gcctaaatca attaaaacgg ccgcaaatac
     3541 tgaaaaagag aaaggaaaaa tatctcggaa ggtttgcgaa atcgttccag gaacttcttt
     3601 aggcatttta atggtaatat ctttcagcac acaaaactta tataaattaa ctgttaaaaa
     3661 tgcagcgaca aaggaagcca gtagtccctt tgtccccata tattccgttg aaaatccacc
     3721 ttcaatcgga gagacgctta acaacaggaa acttaccaca gaggccagca tcacagaggt
     3781 ggtgttgatt actttgtttt tcggtaagcg acgattcatc gaatcagcca agcagcgagc
     3841 agtggttgct gaaacgagta accctacaac acccatcgaa taattataga ctttccatag
     3901 ccatgtggag acagattcag gccattggta accaaaaatc tcaggaaccg cagcaatcaa
     3961 aatgaaaatg cttgaaaata aaatagctgg catcgctgtt aaaaatccgt cacgaacggc
     4021 tcctaaataa ctattacgtg agattttttc aaaaaatggt ttcccttttt cgatttgttt
     4081 aatgattcca tccatagcgt tcttctccta tccttgattc tgtctgtaca gtacaataaa
     4141 gtcttgaatc agatctctca gcaataaagt ggtcattaaa tgatcctgcc catggataaa
     4201 aatgaatccc atctccatct ctttcccaga tgcttcttcc gctaaaattt ttgtttgcga
     4261 attatgtgca agggttaaat tttcgtcggc ttctttcaac gccgaatcaa catgttcaaa
     4321 gtttccttgt cttacttctt tcaataattt caataatgta ctgcgagcgt cgcctgaata
     4381 tgcaacgatc tcaaaaccaa gcatttgtaa ttcctcttta ttcatctttt cttcctccat
     4441 tatcacttat taaataatcg ttttggtttc actgaccaac ttgtaccagt aagctgattc
     4501 ttttgggtaa cgcttctggg tttcaaaatc aacataaaac aagccatacc ttttgttata
     4561 cccatttgtc catgagaaaa gatccataag cgaccacaaa aaatacccct tcacatttac
     4621 cccggctgtt atcgccttgc ttaaggattc caaatagact ctcaaatagt cgattctcgg
     4681 ctgatccata ataatgccat cttcaaactg atctttatac cccatcccgt tctcagtgat
     4741 atagattttg ttgtaatgtg ggtaatcgct tttaattcgc agcaacaagt catatagacc
     4801 ttctggataa atcagccagt cccaatcagt tcgaggaatt ccttctttat aaatacgttc
     4861 tccgattccc ttcactttat aaacagaggt ccctttttca cccgtaccgt tatgatggat
     4921 tgcattttct ccatcgtaag ctttgacaaa atggcattgg tagtgattga tccctaagta
     4981 gtcattacgc gtggatgctt ttttcaattc aacgaaatct tcttcaggaa aatgatagct
     5041 ggcctgattt gcttcacata tctcatcaag agcagtcaag gtttcagttg aataatagcc
     5101 taaataggta gcatctaata agaaacggat cgacaatgca tcgtctaaaa aggcagcatg
     5161 cttatcttcc ggcgcgtctg ttgccgcata tttcgtctct aatgagtgaa ctacaccaat
     5221 ttcacccgga agttcgtttt ctttgaaata gttcactaca cgggcatgag caaccatcat
     5281 attatgaaga caggcgacga tctttgtaaa atcatatttg attcctggtg ggaaaacacc
     5341 taacaaatat tgattggttg caactggata gatttcatta aaggtactcc acaccttgac
     5401 ttctttgaat tcatgaaaac aaaaaatggc ataggaaaca aatgcttcta ttgtttctcg
     5461 attcaaaaaa tctccatggt caaacaaacg tttaggggta tcaaaatgat gcaacgtcac
     5521 aaacggcgtt acgtttcttt tcttacattc ttcgaacaca cgatgataaa aagcgattcc
     5581 ttctggattt ggtttcccag ctccatcagg aaaaatgcgg ctccaagcaa tggataatct
     5641 tagaccattt acaccaaaac gttcacacaa ttcaatgtcc tttgcatatt gatgataaaa
     5701 atcacttgcc ggatcgggac tgaatcgccc ttgttcctct aaaaagtcat cccaagcaac
     5761 agcgcctttg ccaccttcct tagtggctcc ttcaacctga taggctgctg tggctccgcc
     5821 aaaaataaaa tcttctggta atttaagcat gtacatctct cctcaaatct ataatcagtt
     5881 ttcgctcttt ctaactgatt gcattgtaaa cgcatccaaa acatttgtca acaaaaacaa
     5941 acacaaataa tcataaaaac cagaaaacag caataaaatc tattgtaaca aacataaaaa
     6001 ccaccctaaa tgtttacttt tgttcgaatt agattgactg ttgtccgttt atatgataga
     6061 ttatccttaa attagaggtg aagacaatgt tgaaaaaaga aagattgctt actatcgtag
     6121 aaatggtcaa taaaaaagga atccttaccg ttaatgaaat catcaatcaa ttagatgttt
     6181 ctgatatgac cgttcgcaga gatttagatg aattagaaaa atcgggcaag ctgctgcgtg
     6241 tccatggagg ggctcaaagt ctttcctaca ctttagatca agaactttct cacactgaaa
     6301 aagccactct gcagattcaa gaaaaaaaag aaattgctgc cacagcagcc tccttgattc
     6361 acgagggaga aacgattttc ttaggaccag gtacaacaat cgaactattg gcgacgcatt
     6421 tactgaacaa gaaaattcgg atcattacaa ataattatcc agtttttgat attcttgctc
     6481 aagcagatgg accagaaatt ctactgattg gcggtgattt ccggaaaaat accggcgcat
     6541 ttgtcggacc gatcaccaac gacaatttaa gaagactaaa gtttacaaaa gcatttatca
     6601 gttcaaatgg cgttcacaac gaagcgatct ctacttacag taccgaagaa ggagaagcac
     6661 agcagatcgc tctaaataat tcccgtaaga aatatctact cgttgataat aaaaaattca
     6721 atcgagatga tttttatgtg ttttataatt tgcatgattt cgatctgctc attacggatc
     6781 gccagatctc gcgggaggtt caagagcact atgcacaata tgtcgatctg caaattgctg
     6841 attcaaccga aaataccact ataggagcgt aactatgaaa gggattatat ttgatttcaa
     6901 cggaacaatg tttttggact ctcatctgca tgaagctgct tggctgcata tgatacatga
     6961 tcatacaaaa gatggtttat cagacgagga tattttaaaa aatattcatg gtcggacgaa
     7021 tacggagatt ttgaaacatt tcatttcaga gcatttgacc gcctctgaga tcgccgtatt
     7081 gtcagaagaa aaagaaagct attatcgtat gctttgcttg caaaatgaaa acgagcttca
     7141 gttgacaaaa gggcttgaag cgactcttga ccagctgact gaccaacaga ttccattaac
     7201 gattgccacg gctactgtca aagagaatgt tgctttttat tttgatattt tcgatttagc
     7261 ccgctggttt gactgggaca agattgtcta tgacgacggc tctttccctg ggaaaccgca
     7321 accggatatt tttcttaaag cggcagacaa actgagctta gctccggctg attgtcttgt
     7381 tatcgaagat gcttactcag gattacttgc tgccaaacgt gcggggatcg gaacaattat
     7441 tgcaattgat ccattcggta aaaacaaaac agtatttgaa caggcacagc taaataaaga
     7501 tggaaccatc aaagatttta ctggtttttg gacagagcac ctgtctgcca catccgttaa
     7561 ttcttaaacg attcaactaa ctaccaaaga aaagcaactg aaatgcacac ctccttttat
     7621 aaaaaactgc cagtgaaacg acatgaaaga tacactgcta tatccttagt gaaatatagc
     7681 agtgtatctt tgactttttc attcttttaa ccatatgacg cgttcatctc tatctataat
     7741 taacattaaa aatagtgttt tcacattatt tctcaaacca atcttaaaaa tcatcaggag
     7801 tacttttttg atatactttt attaatgctg ggcgtaatgg ttaaaagatt tccactagtt
     7861 cctctccacc aagctgagtt gaaaaatgct tatctgtaaa caacatagac aaagaggaaa
     7921 taaacgtttc cgtatctttc tctgtcccaa ggatattaat taattttcct actaggtaag
     7981 tatcattaaa cttaagatct gccttcacat caaaagtttt gataaaagct tttatcatgc
     8041 gtacaatttt gtctttatcg ccataattga tttcaccact catatcaata tagtcactaa
     8101 tccctgaaga aataatggca actgcttctt ctttcgcctt atcagataat tcatttaatg
     8161 actgggattg attgatgact tcttgagttt tatctgttac gtaatctctc attatcctat
     8221 cggcatactc cgcaaagtaa tcttgaaaaa attcttctac agggtaacca acttcgtttt
     8281 cccaaccagg agaaatttca ttatcagtac ttattaaatc tattaaaaac caacccgttc
     8341 tctgagtgtt gattctataa tatttttaat ttcctatata aatcaaaaat attatagaat
     8401 caataagcta attaagaaac aaactttaga aactctagaa gaacttctga atttatatag
     8461 aagtgtgtag ctacttacta aatatacaaa agttaaaata aaatactctg gatactcttt
     8521 atactgcatt aaagttagta atattaacag caaagatatc gaaaaaacaa taacataata
     8581 tgtgtcaaaa tttttcataa taagaactcc cttactgttg catactaaca taatccaaaa
     8641 actcttctac ttcagctaaa gacattccac tttctttagt ccaaaaaaca gttttttcta
     8701 tcgatccttc tctgtaaact gtaaatgtcg gagtcgagtt aattgagtag cgactcttga
     8761 attctttcca ctcattttca tcttctctaa cttttgctac attcacgtaa taaatatttt
     8821 cttttccctt ttctaccagc atatcgaata gcttcctgct tttgatgatc gatttcttgt
     8881 gctacatcta gtaaattttc atcaatttct ata
//
LOCUS       DAKCAA010000087         8549 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000087 DAKCAA010000000
VERSION     DAKCAA010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.088"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(143..538)
                     /locus_tag="OUE31_002440"
     CDS             complement(143..538)
                     /locus_tag="OUE31_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCU0223412.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(556..1518)
                     /locus_tag="OUE31_002441"
     CDS             complement(556..1518)
                     /locus_tag="OUE31_002441"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HCU0223413.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(1518..1730)
                     /locus_tag="OUE31_002442"
     CDS             complement(1518..1730)
                     /locus_tag="OUE31_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HCU0223414.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(1751..2449)
                     /locus_tag="OUE31_002443"
     CDS             complement(1751..2449)
                     /locus_tag="OUE31_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HCU0223415.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(2469..3011)
                     /locus_tag="OUE31_002444"
     CDS             complement(2469..3011)
                     /locus_tag="OUE31_002444"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HCU0223416.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(3143..4147)
                     /locus_tag="OUE31_002445"
     CDS             complement(3143..4147)
                     /locus_tag="OUE31_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCU0223417.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(4144..5133)
                     /locus_tag="OUE31_002446"
     CDS             complement(4144..5133)
                     /locus_tag="OUE31_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCU0223418.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(5130..5936)
                     /locus_tag="OUE31_002447"
     CDS             complement(5130..5936)
                     /locus_tag="OUE31_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0223419.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            6102..7058
                     /locus_tag="OUE31_002448"
     CDS             6102..7058
                     /locus_tag="OUE31_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCU0223420.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(7135..7653)
                     /locus_tag="OUE31_002449"
     CDS             complement(7135..7653)
                     /locus_tag="OUE31_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCU0223421.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(7741..7890)
                     /gene="rpmG"
                     /locus_tag="OUE31_002450"
     CDS             complement(7741..7890)
                     /gene="rpmG"
                     /locus_tag="OUE31_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCU0223422.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8118..>8549
                     /locus_tag="OUE31_002451"
     CDS             8118..>8549
                     /locus_tag="OUE31_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HCU0223423.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEK"
BASE COUNT         2775 a         1863 c         1456 g         2455 t
ORIGIN      
        1 cttttcgctt agcttatata tgtagataat agcacaaaat aaaaaaaatg aacggcacaa
       61 ctatccattg cgccgttcat gtgatcttgg tcaaaatcta atgattgatt cggtttttaa
      121 agctgtcata caatcatctg ttttatactt ttttactttt gatttttcca gaccatccgt
      181 catatccacc cttaagtaaa taaatctctt gataacctgc tttacgtaat ttatttgctg
      241 tacggatgct caaacttttc ttttgatcgt aaatatagac aggctggtct tttcgaatag
      301 atcctaatga atctttcaaa acagtgtaag ggatgtttct tgcacctaaa atatgcccag
      361 catcaaacac atctttttcg cgaacatcga ttacttgtgc ttttctcatt ccttctcgaa
      421 attcttcttc tgtcaaagtc gttgctgaac gtttggccat tactcgtaga tagacttccc
      481 aaaggatgat tgcaagcaca atcaatagca aaatgatatt aattacccat aaaaccatgt
      541 aatgcctccg tttttttaag caaatttcaa ggctaatgag gcagcaccaa tgacaccagc
      601 ttcattacca agctctgcta atttgatttt tgttgattct cttacttgcg ggaaagtaaa
      661 ttctttaaaa tatttctcta cacggctacg taaaaattct cctgctgccg atactcctcc
      721 acctaacacg atacttgacg gatttaatgt attccccaag tttccgcaag ctaaacctaa
      781 gtagaagcat acgcgatcaa caaccatcaa tgcaaacgga tcgtcttctt gagccatttc
      841 aaagatatct ttacttgtta cttcttctcc gttgtctagc attgctttca gttttgaatc
      901 ccctgcgtat tcttctgcca agaaacgacc taggcgtacc acacctgtag cgctagatac
      961 agtttctaaa catccgcgtt taccgcaagt acattcgaac ccttcaggat ccacagtgat
     1021 atgtccgatt tctcctccag ctccgctcac gccgtgaatc aaatttccgc cagcaacgat
     1081 acctccgcca acacctgttc ctagagtaac gaatacaacg tctggatcgt tttctccagc
     1141 acctttccat cgttcaccta aagcagcaac attcgcgtca ttatcgatag cgaatttgat
     1201 tcctgttcct gcctcgatca gttttttcac aaattgaact tctgtccagt ttaagttata
     1261 cgcaccaata accgttccag cttcgctgtc cacgcttcct ggggtaccca tgccgattcc
     1321 gataaagtct tcggctttca tattatataa attcaaacga tgattgattg attcaatgat
     1381 ttcaggaacg atatgcttac catcatccaa aatattggta tcgatgctcc atttttgctg
     1441 aatctctcct tctggtgtta aaattgcaaa ttttgctgtt gttccaccta aatcaatccc
     1501 aataatcttc ttgtccatta caaatttcct ttctttcggc tttcttcaat tcggtgctct
     1561 ctttttaata tgcgccacgc tgtcatgtat gtatcatgat caatcaaacg gctatcatac
     1621 agattacgca attcgatagt cattaattca atgtcataga tgcgtgcacc cacatagata
     1681 aagatgccaa attttttgaa cagctgctgt acatcatata agctctccat ctttaagcac
     1741 ttccttcata ttatacaagt aaaccatatt tttttaaacc cagtaaaata catattacaa
     1801 aaagaaatac aaaaactagt gtagaaagaa tcctttggtg tatcgaatag cttgtctgtt
     1861 gtttcggtag acccaaaaca ttccctaaca ctaatccgcc aattagccca ccgacatgtc
     1921 cccaaacatc tacagaggta tccagaagac caaaaacaaa tgtcaacaca ataaataaaa
     1981 gaaaatgtct gactagctgc tggatcgctg ggttatgttt aaaatgaaac cctaagataa
     2041 acaacgcacc gaacaaaccg aatatcgaag tacttgcacc accagacaga acattcgctt
     2101 cgttaaaagc aaagcttgct gtatttccca ttatcccgct gaacatataa atcaagaaaa
     2161 aacgccaatg gccatagatt gcctcgattt gctgccccat aaaatacagt atcagtgagt
     2221 tcattacgaa atgcatcagt ccaaaatgga tgaagattgg tgtcactaaa cgccaccatt
     2281 cattgaagtg aacaagataa ggaccataca ttccggcata ataagggatc tcaagtcgcg
     2341 gaaataattc catcatgagg aagaccgctg tctgtatccc taaaaaagca taggtccata
     2401 acggtcgtct taaccatgca cgcaatttta tttgctgttg ataattcatg aaaacctccc
     2461 atttcatttt agtcaataaa caattgttgg atcttctgat caaagctctc cggttgccat
     2521 tgttcattca attgttcacg aaaaacaagg ctacatgttt ttttatgaaa attatttaaa
     2581 taccggtcgt aataaccacc gccaaaaccg attcgataac cggctctatt gtagataata
     2641 cctggtacaa tgaggagatc gatcatctcc ggcaaataga gcttctctga ttgtggctca
     2701 agaacaccaa aactcgaacg tacaagaacg gactgttcat ccatttcata aaacgccatc
     2761 tgacgtttcg gcaaagtttt aggtacaact attttctttt gttctttttc tgctcgttgg
     2821 ataaccggct gtgtatccag ttcaaattca ttcgataaag tcgtccctat cacttttgct
     2881 gacttccagt actcgctggc gaatagctgt ttatagattc gctgttcttt ttcctttttc
     2941 ttgccacttt tggccagatt tttcagcttt tcgattcctt tccggcgtaa tcttactttc
     3001 aattggtcca aaaactcacc cttccttctc tcataaaatg gtataggaaa aaaagaaaaa
     3061 tagcaatcga actttcaaat aaatgcataa atagaataaa aagaagacct agaaatgatt
     3121 ggccttcctt ttttaatgaa tttcaactgt tcagcgcgtg tttttgtctg ataaaaagtg
     3181 catacagaaa atatggcgca ccaaaaaggg caatcaaaat tcctgtaggt acttccccac
     3241 ttggtagaat cactctagca accatatctg cactaagcag aaaaatggaa ccgaacaaac
     3301 cgctcagaac aaaggtccag ttattttctt tacgtacgac tagcttcgca gcatgaggag
     3361 ctagtagtcc tacaaaagat aaactacctg tcaccgctac actaccgctt gccaaagcaa
     3421 cagctaacaa caaaaggatt ttttgacttt tagccacgtt aaggcctaat ccttgcgcgc
     3481 gttcttgacc aaatgatagc aatacaatcc tctgtgcata aagtcctcct agcggaatta
     3541 agataaccgc ccatggaagc aatgcccaaa cataaggcca gctcgcaccc cagattgatc
     3601 ccgctaacca tgcattcaca aatccataat tttccttaga taattggatc gtgcatagca
     3661 atgttaatgc agaaaggccg gcattaacgg caataccgga caataagatt cgattcatac
     3721 ccaaaaagcc atttcgatca taggccgcaa gatagacaca gcaagcagct aaaacaccac
     3781 ctagaaaggc tacaactagc aatagaaacg gcagcgaata gtgcgaaaag aaacctaaat
     3841 aaagcatcac taaaaatcct gctccggcat taatgcccaa tatactagaa tctgccaatt
     3901 catttcttgt tactccttgc aagatataac cagaaacgcc aagacaagct cctgctaata
     3961 aactgatcag taatcgagga actcgaaatt ctctaacaat cagcgccaaa gaagatgatt
     4021 ctttccctat gaacgtggca aaaagctgat ccaggtaaat aaaaggcgta ccaatcatta
     4081 aactacctat agacaggatg acaagtacaa aaagcaagaa atagaacgtc caatatattt
     4141 ttttcaccgt tgttccctcc ttacttgtat cagtaaaaac ggaacgccaa tcaatgcaat
     4201 gactaatcca aaaggtgttt caaaaggggg attgatcatc ctcgctgtaa aatccgccaa
     4261 cataaccaat ccaccgccaa ctaaaaaaga gacaggtaga acataacgat agtccgttcc
     4321 aaccattccg cgaacaactg gcggaaccaa cagcccaata aatgaaacag gtccgactaa
     4381 cgaaacggca atggctgcta acactgcaac tagacagaaa acaatcaacc gcgttcgttt
     4441 aggatgactt ccaagagcta atgcatgtgt ttcactcaaa tgaatcaaag atattgcttt
     4501 tcctaatgaa aaagaaacca aaacagcaag tatatataaa ggaaacaata ctgctaattg
     4561 tttccatgtg atattggcag ctccgcctac aaaccaaaaa gcaagatcct gctgcagatt
     4621 aaagaattgg gtaagtgctt ggctgatagc agtaaaaaaa gaactaatag ctacgccagc
     4681 taaaatcagc tgtaaaggat tcatgcccat tttcgaaaac tgcaaaaaac caaatacgag
     4741 caaagttaca gcaaaagaac ctgccaatga cattagaaac acagaaaaat cagaagcttt
     4801 aggccaaaaa gcaaaactaa gggccattgc caacgaagca cccgcgttga ttcctagtaa
     4861 gcctgaatct gctaaaggat ttcttgtcac tccttgcatc aatgcaccgc tcaatgcaaa
     4921 acaactccct acaagaaatg ctcccgccac acgaggcaaa cgaatatttc gtatgatttg
     4981 gtgactttgt tttgatctat caaaatcaaa caacgcctgc caaaaatctg ctttttccac
     5041 agtcgctgcg ccatttgaaa gagcaacaaa aaaaataatc aaaagaacaa aacagaccaa
     5101 aagcaggagt ctatttttct tcatagtcct cataattgat cctcctgctc ttttggcaac
     5161 aaatcatagg ttagaaaaac tggtttattt gttcttggaa gcgtgacaat cgttgcatca
     5221 atctcaaata tttttttcat acactctttt gtgatcactt cttcaggtgt accttctgtg
     5281 atcaacttac cgtttttcat tgctaataaa taatctgaaa aacgtgaagc atgattaatg
     5341 tcatgaatcg acatcaagat cgttgtttgt ttcatttgat tgatttcagt caataactgt
     5401 aggatctcta attggtgtgc cggatctaaa aatgttgtcg gttcatccaa gatcaagata
     5461 tctgtttcct gagcaagcgc catagcgatc cagacacgct gggtttgtcc accagacagc
     5521 gttgcgatat cccgcatacg aaatccagct agacctgtag catccaacgc ccactcaatt
     5581 gcttcatgat cttgcgtgtc catgccactg aacagttttt gataagggta tcgtccgtaa
     5641 gatactactt cttctactgt catacctgta gggtgttcac tagtttgtgc taataatgca
     5701 attttttttg caagttcttt tgaactgtat gtagagatat cagagttatt gacaatgatc
     5761 tttcctgatt tcacaggtag tatacgggta aaacttttca ataaagtaga ttttccactt
     5821 ccatttggcc caatcaaact agtgattttc ccttcaggaa tcgtaacaga catgttttca
     5881 atgatttttt tgttttcgta gccggctgca atgtcagctg ctcttaatct cgtcatttca
     5941 cccatccttt cgctgaaaat cattctcaat tatgacgctg tttcaacatt tcgtcaagcg
     6001 ctactttcat atctatagcc aaatgaagcg gttgacagcg ttcgaaatat caggaataat
     6061 aaccaatgag aaagattctc aattatgtta ggaggaaaga aatgaaatta aaaacaaaag
     6121 tattcacatt atctagcata ttgctgctgg ctggagtact gagcgcttgc tccccctctt
     6181 cagataaaga aacagctaca actgccaatt cgacgacttc atccaatagt actcatacag
     6241 tcacagatac acttggacat aaagtagaga ttccaaacgc gcccaaacgg atcatcggca
     6301 gttacttaga agactatctg attgcactag gggaaaaacc tatcgcccag tggactgttg
     6361 gcagtggttc cattcaagat tatctgcaag atgatttaaa ggatgtccca acgatttctt
     6421 atgaccttcc ttatgagaaa gtgttaagct ttgagcctga tttgctgttg atttcttctt
     6481 ccgctactgt cgaaggcggg aaatacgaac aatatagcaa aatcgcgcca acttatgttg
     6541 taaaaaacgg aacagatgtc acatgggaag aacaactaaa agatgtcggc aaagctttgg
     6601 caaaagaaaa agaggcagaa aaaatcattt ccgattatca aaaatccatc aagaaaactc
     6661 gagaagaact agcagataaa atcgagaaca agacagctgc agtgttgtgg gtgaccaaca
     6721 actcagcctt tatggtcagc aaaaatcggt caagtggaag aatcgtatac gacgatctgg
     6781 aatttggtgt tcctgatcta gtggaagagg tctccaaaaa agccacttct gactggtctg
     6841 ctgtttcctc tgaaaagcta gctgaattag atgctgacta catcatcctt gtgaacagtg
     6901 acaaagatgc tgccatgttc aatgaaccaa gctggaagaa tctaaaagca gtgacagaca
     6961 atcatgtact gcaattcgga cctgaatcta gttggctata taacggacct attgccagtc
     7021 aggaaatggt caatgatatc aaagaaaaac taaattgatt ttaactaaaa aaagcatctt
     7081 cacgattagt cgtgagatgc tttttttctt attaacaaac tagacgcata gattttattc
     7141 ttcttttgaa gcaaccctat tttttactct ttcccatttt tgaaaacgat gggcatatag
     7201 attttcttga tccgttatcc cctcatactc ctctataagg gcgaagtctg aaaaatcaat
     7261 attcccaata tacgtatcgc cttcaaacgt gctatcgatc aatgttcgcc agatccgacc
     7321 agtgtaagga agaagttctt gaaaaatccg actaccaccc gaaacataga tatcttctga
     7381 gatcgtttga ctatacgaca aaagttcatc gatcgaatgc attacttccg cattttcttt
     7441 cgtgcgaaaa tttggttgcg ttgtcaacac gatgatatgg cgataaggaa gtgaaagatc
     7501 ccccattcct tcataggtct ttcttcccat cactaaaatt cgatccattg tatgttcgcg
     7561 aaagaaacgc atatcatttg gcaatcgcca tggtaacaaa ccatttttgc cgatcagacc
     7621 atttttatct tgtgcccaca tggaaataaa catattatcc gctccttatg attttagatg
     7681 ttttgagata aaaaaagtct caattctttg accagcaagg aattgagaac tttaaaaaca
     7741 ttattttgtt tcacggtgca aagtaacttt gcgttcgcgt gggcaatatt tttgtttttc
     7801 caaacgatca ggattgttac gtttgttttt gcttgttaga tagttacgtt ctttacaaga
     7861 agtacactct aaagtgatgt ttacgcgcat gtttttccct cccattttta caagaatcct
     7921 ctaagatgac tctcagactt gattatctta ccatgatttt ttctagattg ctagtgtttt
     7981 tcacgatttt gttaagtaaa actacttgac gataaataca acggttttac ttctcaaaca
     8041 aaatcttttt ctttttgtat aaataccctt acacttgttt atatagatta tgttttttaa
     8101 taaaggggga tactaatatg ccatggaaca tgaaggactt tcctgcatca atgaaaaact
     8161 tagataaatt gacaagaaaa aaagcaatcg acatcgcaaa tgcattatta gatgaagggt
     8221 accctgataa ccgtgcgatc ccaattgcca ttgatcaagc aaaaaaatgg tatgaagatg
     8281 ctagtgaatc agaaaaacga actttcgaaa aagaaaaaaa tccaagcaag acggatgaac
     8341 acgatacgaa tcctcgtgct ggaaaactgc ttgattcaga tgtgatcgta gaatatgagg
     8401 aagaacaatg gatcgtgaaa tctaaagggg caaaaaaggc aagcaaccat tttgatacaa
     8461 aaaaagaagc aatcgaaaaa ggaaagcaag tagcacaaaa caaagaatca actttgttca
     8521 tttataaaaa agatgggaca aaagaaaaa
//
LOCUS       DAKCAA010000088         8400 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000088 DAKCAA010000000
VERSION     DAKCAA010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.090"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..1276)
                     /locus_tag="OUE31_002452"
     CDS             complement(<1..1276)
                     /locus_tag="OUE31_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCU0223424.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQI"
     gene            complement(1417..2019)
                     /locus_tag="OUE31_002453"
     CDS             complement(1417..2019)
                     /locus_tag="OUE31_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCU0223425.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            2264..2470
                     /locus_tag="OUE31_002454"
     CDS             2264..2470
                     /locus_tag="OUE31_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223426.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            2782..3501
                     /locus_tag="OUE31_002455"
     CDS             2782..3501
                     /locus_tag="OUE31_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCU0223427.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(3582..4265)
                     /locus_tag="OUE31_002456"
     CDS             complement(3582..4265)
                     /locus_tag="OUE31_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HCU0223428.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            4483..6669
                     /locus_tag="OUE31_002457"
     CDS             4483..6669
                     /locus_tag="OUE31_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCU0223429.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            7015..7425
                     /gene="spx"
                     /locus_tag="OUE31_002458"
     CDS             7015..7425
                     /gene="spx"
                     /locus_tag="OUE31_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCU0223430.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            7439..7795
                     /locus_tag="OUE31_002459"
     CDS             7439..7795
                     /locus_tag="OUE31_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HCU0223431.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT         3088 a         1375 c         1572 g         2365 t
ORIGIN      
        1 ttatttgtat ataaatcgtt tgagaaaaac gctggttttc aattgatgtt tcaaggaaaa
       61 gataaggatt ggtctttgtc aattcatcca agataaacaa gccaaggcct tcgttttttg
      121 gatttgtttt tgttgagaac cctttttgtt tcaactggtt taacggtaat gtatttgttg
      181 ttgtattgat cacacgaatc atcacggaat gattcttctt gagtatggtc aattcgattt
      241 ttttcttctt tgcagcacta gctccttcaa tcgcattgtc caagataata ccaagcatac
      301 gtacaaggtt taccgtatgt ttcgtatcca gttcgattgg ctcaggaaaa tgaagctgga
      361 cgatcaaccc tttttcctgt gccatcatga gttttaatga cagtaaacta cggatctcag
      421 gaactttcat attatccaac atacttagat tggccggaaa aaggttcatc atctggcgtg
      481 taggtaatat cgtttgatca taataagacc gtaatccttc taagtcgcct tctgaaatat
      541 agctgtgaag agaaaaaagc agattttggt aatcatgttt gaattctctc aagtcttgat
      601 agtttttttc tagatctttg atataatcct gttgcatcct gacttgttgc tctaataact
      661 gatcagctaa tttcttatta gagattttcc aataataaac caagatgatc aggccaacac
      721 acagatatag aatgaaaaaa ctcgtattca aagctaagac atcaggtgtt tcaccagaaa
      781 aacgggtata aaaaataatg atatagtatg taaataatat caatgtcccg atcgtaccga
      841 tcatacggcg gtccacagtg tgaaaccaag tctctaacga tttttttaaa caaaaagcta
      901 ataaagcaga taaaaaagcg gataagacaa tgtgaaaata ctgcaatgaa tctcctggtt
      961 caataaccga agatttcaaa acaaaaaaat cgccgatgct tgttaagtga tctcctaaaa
     1021 gcgacgtcaa taacccaaaa ggaagcgcgt aaaccaattg ttgacgcgaa gtcgaaaaga
     1081 agaaaaaagt aagcatcagc attcctatag caattagagc agtaaaaatc cctaaaatcg
     1141 aatagaccca tccaatcaaa atacaagaaa tcagaatgac tcccgcaaac agatatttgt
     1201 atcggatgtg atggtcaatc aataagatac aaattgtgta aatcaaatat tgcaacgcta
     1261 tggaccataa aaacataaag tacagctccc attgattttt accaaattat agcacaattg
     1321 gcgtattatt tttttaattt ttcagggatt ttgaattcag aactcatacc aaagcagcag
     1381 ccagatacaa aaaagtcaga taagttagtt aattgtttaa tgattgtttt tttcatgaaa
     1441 gattcctcca aaattcatca agtagtttgt aataggaagc aacgtagcta tttctaaaac
     1501 aatcccaagt agcaaatagg tagaaaagta agaagctgag aaaaataacg taatgagaga
     1561 aaaaattaga aacatgctga tcgccttctt taataatggg ggacgtttct cgggttcaat
     1621 gggattgatt gctgtacctc ttgatccata gcgaagcagt aacaaaaagc agctgattaa
     1681 caaaaagacc atcattggga aggagatagt caattgcaga tgtttcatca ccaagggaac
     1741 gccccataaa taaagtagtg tccacagcag acaaacgaat tcagagtcgg aatgcaatcc
     1801 ataagcatat ctgcggatgc agatataaga aagaaaggtg attcctgttt ccgcccatga
     1861 gcctgtcacc agagaaaaga ctagaacgac cgctagtttt ccaagattat tcaataaaac
     1921 ttctaagaca aattttactt ggacatacac catatcttct tccgatttgt ctccgctgaa
     1981 taaggcttct aataatttgt tcacaacttt atctttcatc tcatacgtac ctccaccaca
     2041 aattttatgc taaaaaaaat aaaaaacgtc ttttgtttca taaaaagtgg ttttgacatc
     2101 aaaaccgtca tgatctccta aaaaaatctt cgttttccaa gaaccttacc aaaaaaagtg
     2161 acagttttga tacgaaaagt actttttatg acaagtttgt gctttttcga gtgatttatg
     2221 ttaaaaaatt actgacctta taaaaggtga tggagggatt cttatggaaa atgaacaatt
     2281 gtttgaagtc ggcgaaacat atgcatttaa atctgattta tttgaatcac caataaaagg
     2341 aaaaatagaa aaaatctatg aaaatagtgt gatgatacgt gtcatgaaat gcgcagtaga
     2401 agacaatgat accgctcata atctgcactg gcagttagtt gtacgcaaat caagtacaat
     2461 agaagaataa aaacagataa aatgttgaga gcataaagag gttgtgagtc tcccgtttag
     2521 ctctgagtta caaggaataa tgttaaaaaa cagcttttca tgttttatga atattgcctt
     2581 gtgaccgagg tgttggcagg agaatactgt ttatttgaaa aaagggctgc gacaagactt
     2641 ttgtcacagc ctttattttc atgaatagga gttacttttg gctactttta gagaagtagc
     2701 ttttaaggag cagataaagt caaggctttt atttctataa atgaagtagt aaaatgaaga
     2761 acagatttta ttacaggaag gatgccgata attgtgatca ttgttgcagg aacgatcggt
     2821 gcagggaaaa gcacactaac tgaaatgctt gcccaagatt tagaaacaaa acctttttat
     2881 gagaacgtgg aagataatga agtattgccg ctattttatt ctaatccaga aaagtatact
     2941 tttttattac agattttctt tttgaacaaa cgctttttgg caatcaaaga tgctttcagc
     3001 catgatgaca acgtactaga ccgctccatc tacgaagata gtatgctgtt tcatttgaat
     3061 gcagatttag ggcgtgtttc tgaagtagaa gtaaagcagt atgaaggtct tttagaaacg
     3121 atgctgaagg agttagaaga aatttcgcca caaaagaaac cagatctact ggtttatatt
     3181 cgtgtatcct ttgaaactat gttagcgaga atcaaaaaaa gaggccggga atatgaacag
     3241 ctagaacaag atcctgaact ctattcctac tataaagaac tcaatcgacg atacgaagag
     3301 tggtatgaac agtttgatat atgtcccaaa atagtgatcg atggggacaa atatgatttc
     3361 gtagccgatc cggcatgtgg agaacaaatc gtacaagaaa tcaagatgcg ggcaaagaaa
     3421 atgacagaag aggcagatgc ccagtcgatc cgctacacta caaataaccc gaaagcaaag
     3481 ggaatcttta caactaaata atataaaaac taagcaaatt gctcactcgc agatatttct
     3541 ctgtgagcag catcttgctt agtttttttg attcattgag atcaaatagt gaaccgattc
     3601 gtatgataaa attgccataa atgaaatgtc tgagtgaggg ccatgatcaa aaataaaatg
     3661 gaaacgatca aaatcgaatg ggcgccaaac agatgatgac agaaaacaag gacaatagct
     3721 cctgcgataa aggcaagaac gacacttaga tagtggaaaa atcgatcaaa atctgctttt
     3781 tctttagaaa tacaataatc atataagttc gttgctaccc cttttaaatt tccagttgta
     3841 aataaattag tgtaggcacg cccgttgatt ttatcaaaag ctacccactg gatcgatgca
     3901 gtaaaagcaa tcaaaatcgt tactaatgcg ggatgctcat ggacgggtgt caaactaaca
     3961 aagaaaaaaa tcactgcttc ataatataga acaaacaagc gccagaaatg tttttctttt
     4021 tttctaaaat aatcaattag atactttgtt agaagaatcc ctaagaaaaa gaaaagggta
     4081 gacaatactt ttttaccaac acttagccat tctccgtcaa atgcttggat gatcgataga
     4141 atgatattgc cagtttgagc agaggcaaaa gcaccatatt ggatataagt ataactgtcc
     4201 atggctcctc cgataaatgt cagcaaaagt cctattgtac gcccctcgtg aaaggaagtc
     4261 tgcatttttt tcatcacctt ttatgaatat ttttgtcttc cttatcttag cataaacgat
     4321 tgaaaaaaag gaaaaatttt cagaaaacta aaatcatatc gcttcccatt ttcattttta
     4381 gaaaggtctg ttagtataaa gaaaaaatag acaacgaaac tttaaataac caacttgaaa
     4441 taaacaaatt caaagaagaa agatgggaag gaaatcaatc agttgaatga aaaagaaatt
     4501 ctccgattac aaaaagaatt gaaacgctgg gagaacaagt ataaaaagct tcaacaagtc
     4561 tttcggctac aagaagaaat cattgctacc tatgaagcgg cttatggcga agcacccgga
     4621 cttattgagg aagaagtaca agtaaaagaa agtgaaggaa acagctcttt ctttaaaatg
     4681 atggagaaac gttcctataa tcgcttcaat caagaacaaa aagcagctat cacatatgat
     4741 atgaagaaac atcttcgaat catagcagga gctgggagcg gcaaaacgca aacaatctgt
     4801 gcaaaagctg tttatctgat gacgcaaaaa caagtagacg aagaacgcat actaatgatc
     4861 acttttacaa ggaacgctgc aaatgaacta aaaaaacgag tagataattt cagccagaga
     4921 aaaaccgctg tccatatcgg aacattccat agtatctttt ttaggatata caatgaaatt
     4981 tgtcgaaaat ttcctgaagt agcaatgcaa ggaatacaag gagacttttc aaaggatact
     5041 gcacaaaaag tgaatgctgt tttgcaacag ctgatacgta aatataatct ttatatattt
     5101 gatcaatatg gagaaaaaac gattgcttct cggttagact attggcagaa tatgaacctt
     5161 tcagtagaag aaatggttca gttagttaaa gaaaaatatg attccattga taagaatgca
     5221 cgacagccga tatcagaacg actgtatgga ttgctcacgg aactccaaga acaaaaaaga
     5281 agccagcaat tgctagagtt caatgatgta ctccaaaatc tgaaaagcgc tttggagaat
     5341 gaggagatcc agcattatat cggccaaaaa tatgattatc tattcattga tgaatttcaa
     5401 gatactaatc cacttcaatg ggaaatcgtg aaacggatga caaaggaaaa caggatcaag
     5461 ttgattgttg ttggagatga tgatcagagt atctatggat tcagaggatc agagccagca
     5521 tacatcaaga actttgaaaa agaatatcct accaaaactc ttttcttatt aactaattat
     5581 cgttctcggg cagctattgt ccaaggagca aatagattga tcagctataa taaaaatgat
     5641 cggataccaa aggcgatgat tccagcacaa aaagaagcag gtgttatgga agcctatttg
     5701 ttttctgata ctaaagcaga aagtcagtgg ctaatcaaac aaattcagac atttattcaa
     5761 aaaaatggga aatataagga atcaatcata ttataccgat cagcttcaca aacgcagcag
     5821 cttgtccaat ctctgctgaa aacgaatatt ccttttgtac tggaagcaga tagtccatat
     5881 gaaggtatct ttggtatcaa gtctttccaa catttctatc aaaaaattgt tcattggcaa
     5941 acagcactga atctgcaaaa gaaaaatcag gcctaccagc aattgctccg gcagctgatg
     6001 gcagactgct acctgaaaaa aagtgaatgc gatcaatact tttctcctaa atatcaaaat
     6061 atagccgttg cagattatat tttgtcgata agccccaatt taaaatcgaa atctgcagaa
     6121 atccgagagt ttgaggaagc gttgcgtaaa acagaccagc atcaagaaat ctattcgctt
     6181 gttcaaagct atcttcatct gccacgtata gctaaggaaa tcgaccagag tgatcaagaa
     6241 tggatacgag aagaagtaaa gcagcatgct actttcagaa gactccaagc cttatcgcaa
     6301 gaaacccaag cgacagctaa agaattaaaa acccgcttga ttgcttacag acaaggaaaa
     6361 cttgatgcac tatgtatcca gagcattcac aaaagtaaag gtcttagtta ccgaaatgtc
     6421 tttttgattg gttgtaacga aggaagtttg ccttataacg gagcgacaga aaagaaagta
     6481 atcgacttta atgaaataaa agcagaacca gtaacgacga tagaagaaga acgaagacta
     6541 ttttatgttg cgatgactag agcaagaaat cgtctgtatc tatgtgtacc tcaaatgaaa
     6601 aattcaagaa aattgaaagt atcgagattt atcaaagaaa ccgggagtcg tgtgaaaaaa
     6661 ggaaagtgat agaagagagg gtgtgacaga agtggtcagt ttcaagaaag aagaaggaat
     6721 gtacgaaaat tgcttctcaa atttttgtga aatttcagct tattttcgaa gaagctattt
     6781 ctggaacaca gtttattcgg aaaagggagg tgtgacaaga attttgtcac acctccctta
     6841 tttattttga aaatgagaat actattatca aaatagagaa tatatagaaa aattctcatt
     6901 attcaaacgt aaataatcag ttattttgat tttttttata ttttattagc taataattgg
     6961 tattttaaaa gaaattactg tagaattgga ttataattaa aaaagggtga gaaaatgata
     7021 aaagtatata cttcgcctag ctgtacttcc tgtagaaaag caagagcatg gttgcaagcg
     7081 aatcaacttg aatttgaaga gaagaatatt tttgccgaac cgttaacaga aagtgagatc
     7141 aaaaagatct tggcagcgac tgaaggagga gttcaagata ttatttccac tcggtcgaaa
     7201 atttacgaaa agctgggcat agattttaac gaattaactt taaagcaaat gatcgtctta
     7261 ttcaaagaat atccttcatt attgagacga cctattttga ttgatgaaaa aagaatacta
     7321 atcggattta atgaagatga gatccggtca tttgtccctc gtgaaattcg atgtgttgcc
     7381 agaaatctga tctatttaca aaacaataac atcttaaatt catagggagg gagccttcgt
     7441 ggaagtgaaa gtctatggat cagcgcactg tgtaacaagt ctgaaggcga aacaatggtt
     7501 agaacaccat caattgcctt atcaatttgt tgacttagaa gaacgcgatc taagtacaga
     7561 agaagcagaa gaattatgca gttttgaaga agtgcaagca gaacagctat ttgcgacttg
     7621 gtctgaggct tttcacaaca ttgcgattga cctttcctgt gtaggaaaaa aacaactgat
     7681 ttttttatgc acacaacata ccaatctcct cagacgtcct ttgattatta tcgatgaagt
     7741 tctatttatt ggatacaatg agcagttgat ggaacagctt atcttaaata aatagacttt
     7801 aactgtttta atcaagtcac tgagcatttc atacagttgt aacagtcgaa cacttagcat
     7861 caagcgtgtt atgtgttctt tttttgactt tatttttcta ctatagagac atgctcaatt
     7921 tatgtggtca aaattcaaat ctaggtgggg atatagagtt aaaaatatat tgacatgtgt
     7981 aaatttacat gatatattca tttctgttgt tttaagtagc aaagcaataa aatagtattt
     8041 taaaaaacat ataaaatagt tgttgacatg ttagaaatga catgataaga taactgagtt
     8101 gttaaaaaag aaccacttgt gaagcttgat tctatcgaaa aaaacttcaa aaaagttctt
     8161 gacaaataac aaatgataag ttatgataaa tgagttgctg taagatttcg aaaaacgaaa
     8221 tcaaaaaaac ttttaaaaaa gagttgacaa ttacttgtct ctctgatatg atataaaagt
     8281 tgctacggca gccaaaaacg aatcggggaa cactcctgat gaagtagacc tttgaaaact
     8341 gaacaaagta agacaaacca aatgtgtagg gcgtcttgat tcaattcaag acaacaaaca
//
LOCUS       DAKCAA010000089         8300 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000089 DAKCAA010000000
VERSION     DAKCAA010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.091"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(51..1517)
                     /locus_tag="OUE31_002460"
                     /pseudo
     CDS             complement(51..1517)
                     /locus_tag="OUE31_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
     gene            1904..2500
                     /locus_tag="OUE31_002461"
     CDS             1904..2500
                     /locus_tag="OUE31_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCU0223432.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2558..3040)
                     /locus_tag="OUE31_002462"
     CDS             complement(2558..3040)
                     /locus_tag="OUE31_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223433.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3146..3343)
                     /locus_tag="OUE31_002463"
     CDS             complement(3146..3343)
                     /locus_tag="OUE31_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223434.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3638..4396
                     /locus_tag="OUE31_002464"
     CDS             3638..4396
                     /locus_tag="OUE31_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HCU0223435.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4456..4884
                     /locus_tag="OUE31_002465"
     CDS             4456..4884
                     /locus_tag="OUE31_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223436.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4930..5002
                     /locus_tag="OUE31_002466"
     tRNA            4930..5002
                     /locus_tag="OUE31_002466"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4963..4965,aa:Gln,seq:ctg)
     gene            complement(5152..5523)
                     /locus_tag="OUE31_002467"
     CDS             complement(5152..5523)
                     /locus_tag="OUE31_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCU0223437.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5738..5923
                     /locus_tag="OUE31_002468"
     CDS             5738..5923
                     /locus_tag="OUE31_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223438.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6006..6194)
                     /locus_tag="OUE31_002469"
     CDS             complement(6006..6194)
                     /locus_tag="OUE31_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223439.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6218..6481)
                     /locus_tag="OUE31_002470"
     CDS             complement(6218..6481)
                     /locus_tag="OUE31_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223440.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6639..6896
                     /locus_tag="OUE31_002471"
     CDS             6639..6896
                     /locus_tag="OUE31_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HCU0223441.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6967..7158)
                     /locus_tag="OUE31_002472"
     CDS             complement(6967..7158)
                     /locus_tag="OUE31_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223442.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7299..7619)
                     /locus_tag="OUE31_002473"
     CDS             complement(7299..7619)
                     /locus_tag="OUE31_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223443.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7642..8076)
                     /locus_tag="OUE31_002474"
     CDS             complement(7642..8076)
                     /locus_tag="OUE31_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCU0223444.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
BASE COUNT         2634 a         1635 c         1316 g         2715 t
ORIGIN      
        1 aaaaacagga actgctgcaa ataagcaatt cctgttttta tgttcattga ttaatgaata
       61 gagcccatta gttttttgat tggttctttc acagtaaata gcaagatacc accgacgatt
      121 gctactgcac cgataatacc gaagtaagca gattctgttc ccggtgtgta gaagcgtgca
      181 atttgtgcat tgattgcttg tgaagaagca tcagctaaga accaaatagc gattgtttgt
      241 gattcaaatg ctcgtggtgc taattttgtt gtcacagaca aaccaactgg tgaaagacac
      301 aattcagcaa taaccacgat gaagaaactt cccaacaacc acaatggact tacttttcca
      361 cttgtaccat aaagcatacc cggcaacatc aatagcaagt acgataatcc tgcaaataaa
      421 agtccaagag agaatttcac tactgtagat ggttgacgtt caccaagttt cgtccacatc
      481 gttacgaata ctggtgtcag aataaagatg aaaattggat tcaatgattg ataccagctt
      541 gcttggatcg ttacaccaaa tagcgtagat tgtgtacgtt cactagcaaa taaagctaag
      601 atagatgaac cttgttcttg taatgaccag aaaatgattg ctgcaaggaa taatgggata
      661 taagctcata ctcttggttt ttcttcagca gttacatctt ttgaagtcag cattttgata
      721 aagtaataca acggtaagat aatccccaat acactgattg tattgacaaa aaagtcaatt
      781 gtcagatgac cagttagttg tgccccgccg aatactgcag cgataacaac aagtgcgatg
      841 atcaagttac ggatgaatcc tttacgttct tcagttgtca aaggattcgg cggtgttgta
      901 cccactccgt ctaatgtctt gcgtccttgg atgatgtatt gtaataatcc aaagaacatc
      961 ccaatagcag ctaaagagaa ccctaaatga tagttatatt cttgaccgat tgtaccaacg
     1021 attagtggtg ctaataatgc ccctaagttg acacccatgt aaaaaatcga aaatcctgca
     1081 tctcttcgca agtcagtctt tgaataaaga tgtccgacca tgccagaaac atttggtttc
     1141 aaaaaggcgg ttccgataat aatcaatgcc atcgaaacaa acaatgtact tacaccaaat
     1201 ggtaaagcca agacgatgtg gccaagcata atgaaaactc caccgaagaa tacagtgcgt
     1261 tttgctccta acactcggtc agatacccat ccgccgacga tactagacat gtagatcaaa
     1321 gatccgtaga tcgacatgat agctaatgct gttgctcgtg gtaatccaag tcccccgttg
     1381 gcaactgtat cgtacatata atagataagt aatgcacgca taccgtaata actaaatcgt
     1441 tcccacatct cagtgaagaa caaagttgac aatcccttcg gctgcccgaa gaagcccttg
     1501 tcttgctgtt tttccataat ctatacccca attctttaaa ttttcagaaa atattataca
     1561 tctttaccga aaaatttaac taaaaaactt atttaagaaa tataaactaa ttttctataa
     1621 aagcaagtaa tttttaatgg caatatcata aaaaaaagaa gatagagatt taataattat
     1681 atatcagctg tttttttcaa ataagcaaaa attcctaaaa cacaacaatg aaagcgataa
     1741 ctaagaaaat ccttacataa cgatttttct tattaaaatt gttttttgaa cttcgcttat
     1801 tttttgtgag catatctgtt tacttacttt ttgtaaggtg ctatacttca tttcgtaatc
     1861 aattaaaaaa atgcaaaacg caaatcaaag gagaaatttt attatgacaa cttttactga
     1921 cactttgaaa aaccgccgtt caatctatca tctaggacgt aatgtttcac tttctaatga
     1981 agaattaaca actttgatca aagaagcaat taaagaaagc ccaactgctt tcaatgctca
     2041 atcaacacgc gcagttatcc ttttcggaga tgcacatgaa aaactttggg aaatcactga
     2101 agaagcactt cgcccattga ctccagcaga agctttccca aatacacaaa acaaattagc
     2161 tggtttcaaa aatggttatg gtacagtatt attcttcaaa gatactgacg tggtaaaagg
     2221 tctacaagaa caatttgaat tatatgcaga caacttccca gattggtcag aacaatcaaa
     2281 cggaatcgca acagctaata cttgggtagc attagttgat aaaggattgg gcgcaaactt
     2341 gcaacattac aacccagtta ttgacgaagc agttgcaaaa gaatggaata tcccttcaaa
     2401 ctggaaacta cgttcgcaat tagtattcgg ttcaccagaa acaccggctg gggaaaaaga
     2461 atacatgaac gatgccgatc gcttccgcgt atttggataa ttttatttga aataaaaaac
     2521 agaggttgtg acaaacatct tgtcgcaacc tctgttttta ttctggatca atcataatat
     2581 caatctctgc ctcatcgttt aagcgttggg acaaaaatgg aactaattct tctaatgatg
     2641 cagaaaattt cagcatcggt cctcgccatc cgtttcggaa aaaattcatt tttacgattt
     2701 tagaaccttt tggctgatat aatacaattt tattgatctc agaaaaagga acaccttttt
     2761 tgtcaaagct attcaaaaca agtccttctt ctgtgattcc tctactgtcc aacaaaaaac
     2821 taataaaaat cattgctgac aagatccctt ttgccaattc atctgctgta ggatgactga
     2881 tgagtgtata ccaaatgact agtgacacta agaagggtat caccaagtag acccatcgat
     2941 ttcgcacagt ccgataaata atttcttttc gaaccagcca aagaaataaa aacatcacaa
     3001 caacgaataa aaacaataga accgtaaaga atgttaccat gacaactcgc ctcgcttttt
     3061 cttctccaga aaataggaaa agaatactga tttaccttct caaagaaatt ggacttgcag
     3121 cacgccgcac gtccaattgt tttctttatt caaatgtatc atattttgca acaaccatgc
     3181 ttgctttttc atctaataat tcttggtcct ctgcagcaca ttgggcaact ttgaccacgg
     3241 cgcagtttgt catttttgat acaacttcac caatgaccgt ttttgtaaaa ccaattggtt
     3301 tgcatgcata ttgttctcct aaattaatca tttcttccgt catcaaaatc ctcctaaact
     3361 gctggaactt ttctccacat taccactgct atttctttgg agatttaact cattgatttt
     3421 tatttacagt taaaaatcaa ccttacaggc attatagcgt actgttttcg ttttcacaat
     3481 taaaacagct gttgtattta gaagaatttt tttcaaaaaa ttaaaacata ttccttaaaa
     3541 actaattatt tcctacatat taaaatataa tacttccatt tccaataaaa atacatttat
     3601 aataggaaag ataaacagct gaaaagggag atttcaaatg aagaaaaaaa cgttcaaaaa
     3661 actattgttt ctagggggca cagctgctct tttattaagc ggtacaagtt attacctaca
     3721 tatccattct ccagaacata caatgaacac tgcacaaaaa agttcaacac aaaaaacgaa
     3781 aaagacaaaa gagaaagcag aagttttact agatgttcca ttagagagcc agtttgattc
     3841 tccttcttta gaaaatggct gtgaagtcac ttcgctttct atgcttttat ctttttatgg
     3901 ttatgaaaca actaaaaacc agttagctga gcaattggat tacgtccctg ttttcaatgc
     3961 agatgggact catggcgatc ctaatgaagg atttgttggt gatatcagtg gcggagactg
     4021 ggctatggtc gtctatgttc ccccagttgc ctcccttgct cagcaaatcg tccaaacgga
     4081 ttatcacact tttccaaaaa ccgatgctca actcgatgat atcaaaaaag cactatctaa
     4141 aggaaatcct gtctggactt ctgtgactat caattttgaa gtcccagatg aaactgattt
     4201 tatgacttgg accacaaata atggagaagt aagagtcact cctcttgttc atgcttgtgt
     4261 agtcactgga tatgacaaag aaaatattta tgtcaacgat ccctatggtg taaaaaatcg
     4321 agcagtaccg atcaacgatt tttcggcgat tttcactgca atgggtggac agatgctaac
     4381 tttggagaaa agctagtaat tcaaacaaaa atcccttata ctcaagatac caaacctttg
     4441 aagggagcgt agataatgga aaaattcaca cataaaaaaa tggatccaaa tgaaattccg
     4501 attatttttg tccgtgactg caagggaaat gttcaaggta aagtctctat taatgagtgg
     4561 aacgagcgtc gcagacctgc taccctcaat gaactggaaa tcaaattgta tcgtcaatct
     4621 cttgtttatt acgcagatca agagtacgag aaagccaccg atttattgaa atttctaatt
     4681 gctcgaacag agtatactcg ctttgaatat attgaacgtt tagcaaacat ctatcatatt
     4741 atgaatgaac ctgtcaaaga atatcagtta ttggacaccg tcttgtcagt agcagaactg
     4801 attgcccttc ctgctggatt agaaaagaaa ctagtacgcc gccttttacg agtaaagcaa
     4861 caactatccg atcaagaaaa ataacttgcg tttttttagg aaagtgctat gattattttg
     4921 ttgaataaat gggatgtagc caaactggta aggcacttga ctctgaatca agcaattgta
     4981 ggttcgaacc ctgccatccc aatttgatgt gcttgctgaa aaaatgaacc ccctgtaaaa
     5041 gaacaatctt tttgcagggg gattattgta ttatttttac tacttgtatt tagtttacat
     5101 aattaaatta tgaataataa aatcgggcgt attcttaata caaaaactga tttacccaat
     5161 aattgctaat gctttctccg gaactttttc tctaggaact tcctcatacg tttctatgtg
     5221 tgctccttta ttgctaattt tcaaataatg attttctttt aacacagaaa gaccattaaa
     5281 ttcaaccgtt cgttctttcc cattggcatc agcagctttc tgcacatacc ttgctgtacc
     5341 atattcattt acttcctctg gtttttgtgt ctttacatag acctctcctt tttcaactaa
     5401 tggatttagc tgatcaagta taccagggat ttctccataa cttccttcag tataatattt
     5461 cagtccaaat agcaaaatac cactaatcgc cgccagtcca atcaaatatt taatcacttt
     5521 catctttcta cctccttgtt atatattcag tatatgggtc agttaaagaa attccatccg
     5581 tcccaagttg gagatttttc tcctacttta gaagcgagaa tcgagtgttt ttttagtaaa
     5641 aatgatcgtt atttgatatt attgacgtgt ggataaatca gtttttctcg ttttgtccat
     5701 gtaaaaaatc atgttgatag caaaggatgt gttcaaaatg aatcaagaag aattatttca
     5761 aaaagtcaag gaaatgatta agaacggcaa tttcgatggc gcaaaacgat ttatcgaaga
     5821 acataaagaa caattaggac cttataaaga gaaagcccaa aatcttttaa aagatgtaaa
     5881 tatcgacagt gtcaaaaaca aatttaaaaa tctattcaaa taagtaaaac tttcactttt
     5941 gtaaaatcaa aggaggacaa tgctgctgca tcgtcctcct ttggttcttt tctgaatact
     6001 tcatactaaa ataaacgtgt cggatcgtaa tgataagtca cattgccgtt cagtgaggct
     6061 tttcccacca catatttacg attctccaac ttcagccacg cttctcgaaa agccattaat
     6121 tcttctcttt ttacatcaat cttttcgatt tttccatcga tcaaatcttg aataagttgt
     6181 tcatatggat tcattttttt cctccatctg ctgtcaatca ataagttgta aaaataggtt
     6241 catatgcttt tttggtatct agatcttctc tgactttgac tgtcgtataa ataatttttt
     6301 ctactgggat actataataa cttccttcac cattattgaa tcggtgaacg tctttctttg
     6361 ctaaaatacc atttatttta ttcgtcagta cacgttgttc gacactgtta cttacaacat
     6421 agtaaatcac ccgaatatta ttgatcaaat gcaaatcgat ttctaacact acatgatcca
     6481 tgaaaatccc actccttctt tcactttgat tatagcaagt ttctcctcta atttcaaaat
     6541 cgatacagat tttaccggat aaatccacaa aactgcttgc gccatttcgc acaaagtgtt
     6601 attttgtatc atggacttta tttatcggag gcaatagtat gatcgcgatc ggtcaatttg
     6661 ttttttatat tccttttttt attatgataa gcattctttt ctattacata aaatggacaa
     6721 aaaagaagtt ttcagtttta ctggcctctt tacctgctgt atattttact tatcaaattt
     6781 tttcttttag gcattgggaa acaacgtctg tattaataac acacatcatc gaattgacgc
     6841 tttcagtaat ttttcttatt atttggatct attttttata taagaatcag aattgaatcc
     6901 ctcgcatgtt taaaaagaaa acgattaaag atgcagcaaa tttctgccga tctttaatcg
     6961 ttttttctat tctgttatac caaaaaaatg tttgaatcgg tgaaggatcg ttccttgttt
     7021 taattctata aattcttgtg cgatcgggta cttttcttcc aaattttctt tgttcttttc
     7081 gatcaggctt ttcgcttctt catatttttt atctgcacat agtgctttta cttcctgtaa
     7141 tacttttcct gcttccattt gcctcaccct cttgccattt tattgcttta agttttattt
     7201 aagttatacg cattattcta gtttcatccc aaataacctt ttttcatttt tactcctcga
     7261 actaatcagt tttctaaagg ctgattggtt cgtctttttt atttttcctc catttcattc
     7321 tgctcttctg ttaatttatc taatgctttg attgatgctg cggctcttgc ataatcatag
     7381 ctgtataatt ccataaattt atcaggcaga acaaaccacg ctggatgata accgttagct
     7441 gtgacaggga atcctttatc ttgttggtta tctccatccc atctcagagc aacacctttt
     7501 tttcctttcc actttactaa agcgatcgag tatcccttct ttgtttgtgt gccgtcttca
     7561 ataattgcta aaatttctat tttttctttt ggcgcacgga cttcttgagg acgaaccatt
     7621 ttctattcct cccttatctc attacttcac gaccaacaca ctgcaagggg catgtgatac
     7681 gacataagaa gcggtcgatc caactaatgc ttgttgtata gcaccttttc ctgtcgctcc
     7741 cataacgatc aaatcaatat tttcttgtcc agggatgaca ttggcaatca aatttcttgg
     7801 atctccagtt tcaactattg cgtggatctc agcaatgccg tactctttgg catcattgat
     7861 ttttttcagc atggctactt ctgttctttg tttttcatct gcatagattt ttgaaaaggc
     7921 ataggcacta tgggtcagct caactttgtt gatgattgac acgataaata agtgggcttc
     7981 attgtccttt gctaagtcaa gggcttcagc gaacgctttg atcgattgtc ttgatccgtc
     8041 aactgctacc atgatgttct ggtatctttt actcattgga accgcctcct ttttctttta
     8101 ttgtaacatc tcaagcaaaa atacaaaaaa tatacgcaat atgtaaataa aatgatgaac
     8161 aaaagcaatt tctttcaagt tatttataca tttcttttct catcagaaca cctgttctaa
     8221 tcccattatt tctgcattat gtgaaattcc tcatcatttt tcacatcgag cgaacatcat
     8281 tctgttacaa aaaacgtgga
//
LOCUS       DAKCAA010000090         8192 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000090 DAKCAA010000000
VERSION     DAKCAA010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.092"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     regulatory      44..123
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            121..1314
                     /locus_tag="OUE31_002475"
     CDS             121..1314
                     /locus_tag="OUE31_002475"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HCU0223445.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1444..2916
                     /locus_tag="OUE31_002476"
     CDS             1444..2916
                     /locus_tag="OUE31_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0223446.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            2999..3787
                     /locus_tag="OUE31_002477"
     CDS             2999..3787
                     /locus_tag="OUE31_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HCU0223447.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(3854..4522)
                     /locus_tag="OUE31_002478"
     CDS             complement(3854..4522)
                     /locus_tag="OUE31_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HCU0223448.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            4637..6349
                     /locus_tag="OUE31_002479"
     CDS             4637..6349
                     /locus_tag="OUE31_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0223449.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6352..8124
                     /locus_tag="OUE31_002480"
     CDS             6352..8124
                     /locus_tag="OUE31_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0223450.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2505 a         1379 c         1806 g         2502 t
ORIGIN      
        1 atgaaaaaat acgagcagaa aactgtttta tctgctatac ttggttcgtt gcaagttccc
       61 gaaaggatcc gcaggacgga gatgccttgt aaccgaattt aactaggggg aatcattata
      121 atggtagaaa gacacttatt tacatcagaa tctgtttctg aaggacatcc agataaaatt
      181 gctgaccaaa tcagtgatgc aatcttggat gcaattttaa aacaagatcc aacagcacga
      241 gtagcgtgtg aaacgtctgt aacaactggt cttgttttag tatttggaga aatatctacg
      301 acggcatatg tagatattca aaaagtcgta cgggaaacaa taaaagaaat tggttataca
      361 cgtgcaaaat tcggatttga tggagataca gcagctgtat tggttgcgat tgatgaacaa
      421 tctcctgata ttgctcaagg agttgatgaa gcacttgaga tccgggatga agataaaaaa
      481 gacgtattag atgagattgg tgctggtgac caaggtttaa tgtttgggtt tgctgtagat
      541 gaaacaccag aattgatgcc tttaccaatc gctttgagtc atcgtctggt acgacgcttg
      601 gcagatttgc gtaaatcaaa tgaattaacg tatttacgtc cagatgcaaa atctcaagta
      661 acggttgaat atgatgatca aggacaaccg gaacgcgtag atacaatcgt tatttcaaca
      721 cagcatgatg atgcagtaga taatgaaaca attcgtcatg atgtcatcga aaaagtagtg
      781 aaggaagtta ttccagctga attattagat gatcaaacga aatattatat caatccgact
      841 ggccgatttg tcattggtgg tcctcaaggg gatgccggat taacaggaag aaaaatcatt
      901 gttgatacgt atggcggtta tgctcgtcat ggtggcggtg ctttttctgg taaagatgcg
      961 acaaaagttg accgttctgc cagctatgct gcacgttata ttgctaaaaa cattgttgca
     1021 gcagggcttg ctcgcaaagc agaagtacag ctagcttatg cgattggtgt tgctcaacct
     1081 gtttcgatct caatcaatac tttcggtact ggaacggttc cggaagaaga actgattgct
     1141 gcagtgagag aaaacttcga tcttcggcca gcaggaatca tcgagatgct tgatttgcgt
     1201 cgtccgattt acaaacaaac agctgcttac ggtcattttg gtcgtacaga tgtagatttg
     1261 ccttgggaac atacggacaa agtagatgcg ttgaaagcaa gtttagcaaa ataagttata
     1321 ttcagctgga acgatcgcca agtggtggtt gttccagctt tttttatggc agttaacctc
     1381 ttgaaaaaga tagtaattat ttatctattt ttagatcctg tcataatgaa agggaggaat
     1441 aagatgaaaa aagaaacaaa tgttactttg gtcacagtga gtattttcat tgcaacgttc
     1501 atgacggcta ttgaaggtac aatcgtaaca accgctatgc caacgattgt cggttcatta
     1561 catggaatgg aaatcatgaa ctgggtattt tcgatttatt tgctgacaaa cgctatgctt
     1621 actccgattt acggaaaact tgcggataaa gtgggacgga aaccaatctt tatttttggg
     1681 acattattgt ttattatcgg ttcgttattt tgcggtttat ctcaaagcat gattgggttg
     1741 attgctgctc gtgcgattca agggatgggt gctggggcaa tgatgccagt agctttgacg
     1801 atcatcggcg atctttattc tattgaaaag cgagcaaaag ttttaggttt gaatagttca
     1861 gcctggggga ttgccagtgt ttttggaccg cttgcgggag gattcatcgt tgaaacgatc
     1921 agctggcact ggatcttttt tatcaatgtg ccgatcggaa ttctattaat tattttgatt
     1981 tggctatatt taaatgaacc aaaaatcata catgagtcta aaccaatgga tatttttggt
     2041 agttttagtt tgatggccat gcttgtctca ttgctgttag ggttccaatt attaggagac
     2101 gaaggaatga gtccgcttgt ttctgctttg ctgctaggta gtatcgtaat gttaggtatt
     2161 tttgtttttg ccgaaaaaag agctaaagat cctgtcatca tgatgcattt attcaaaaat
     2221 ccactatttg ttgtggtcaa cttggctgca gcattggcta gtggtttttt gatgggaatc
     2281 gatgtttata tccctatgtg gatgcaaggt gtattagggc tgaatgcagc aattggtggg
     2341 ctggtattag caccattatc actagtctgg atggtcggtt ctttccttgc aagcaagtgg
     2401 atgactcaaa tgaaaactca ttgggtcttg agaattggac tactaatcgc agctattggg
     2461 ggcgcttggt tgtatcttat gcctttcaga agtaactatt tatggttttt tgctatatca
     2521 acggtcatcg gtataggctt aggtgtgacc atgactacct cgactgtcag tgcacaaaat
     2581 agtgtatctc gtgaccagct tggtgtagca acttctttta atacgttagt tcgaacaatt
     2641 ggtcaaacag tcatggtttc tatttttggt ttattgataa atggggtaac taaacgagaa
     2701 cttgcagcag caaatttaac aaatgatgca gatatcatga ataaactggt gaatccacaa
     2761 acggctaaat atattgatgc ggatattttg ttaccattaa gaaaaattct ttatgatggg
     2821 ttacattccg tttatctagt tggcttgtta ctcgtgatca ttgctttggt cttaacgctt
     2881 ttcgttcatg aaaaaagtgg taaaataaaa cagtagtttc ggttaagata tgtacgtagc
     2941 cgaatcattc aaatttaaag ttattcaaaa ataacttctt actaaggaag gcgaaaatat
     3001 ggcatttatt caagcaaata tttattcgaa tgtgttagaa atggaagtca atctaaatgt
     3061 gatactaccg caaacaacaa aaaaggtgat tggcaccagt tcagagcaag agacaacgga
     3121 tatacctgtt ttatatttac ttcatggaat gggtggcaat catagtgtat gggaaagacg
     3181 tacgtcgatt gaacgttatg tagcaaacta cggattagct gtcatcatgc catctactga
     3241 tcttggctgg tacacagata cagtttatga catgaagtat tggacattca ttgcagaaga
     3301 gctacctgag atttgtcatg aattattccc gcaattaaca agaaaaagag aaaaaacata
     3361 tgccgctgga ttatcgatgg gcggatatgg cgcgttaaaa ctaggccttg caaaatcaga
     3421 aaatttcgca gcagtaatct ctctttcagg cgctgtttct gtaggaaatc gaatggatga
     3481 tcttttgatg gttcgtaaag catctttttg ggaagggatc tttggaccat tggatcaaat
     3541 cgaaggttca aaaaatgatc cgcaatactt attgaaagaa ctagtaaaaa gcggaaaacc
     3601 agttccaaga ttttatatgg cttgtgggga atctgatttt ctttatcagg caaatcagga
     3661 aatggtatct gctatgcagg aacaaggctt ggcggtcacc tttgaacaag gacctggcga
     3721 tcataactgg atcttctggg accaatggat tcaacgtgca ttggcgtggc taatggaaga
     3781 aaaataaaaa aagagtctta aaaagatagc tcctatagag atcacaaaca tagtgatctc
     3841 tataggagct tttttactgc tcgttttctc ttcttttatt ttgttggcat aagccttcaa
     3901 tataggtttg tgcactcgtt agaaagagtg ctttttcatt caattctgca tgggactgca
     3961 tactttcttt aaatccctct aattgatttt caactacata attacgcata aatagaactg
     4021 tttctttcaa aaattcattt ccgtccataa ttttttgtcg aagctgctgt tcatgctgct
     4081 gatccattaa ctgtccaatc aataaattgt ggagagaggc aatggcctga tgactttggg
     4141 tgactgaaaa tccttcacga acaagtaatt ggatcatttg ctccaaatgt tctaatcgac
     4201 tcggaaaagc gggcacagta ttgatttcta attctgcccc acaagggaaa cgtgtataaa
     4261 ggtcatagta attttccata tactgcagca actgttcatt ccaaggcaaa gttggatctg
     4321 gaagcgctaa ttcttcttcc attgtttcag ccattttttg caagagctgt tgtttgtttt
     4381 tgaaatacca atataaagca ggtgcttgaa catgaattct gtttgcgatg tttcgcatgg
     4441 aaagctgcga aagagcttgt gtttcagcca ggatatcaaa ggcggcctga atgatgattg
     4501 cttgagaaag ctttatttcc attttatcaa cctcgtgtat tgcattatct ttttaaacat
     4561 ggtaaattgt tagtcggtct aattttacag tgttaaatta gtcctgtcaa tttaaacaaa
     4621 ggggtgtaat caacgaatga aattaatctt acgacatgcg aaaaaatata aagtagctgt
     4681 ttttatttcc ttgctgtccg tagcagtcat ggttgcagca gcattatggc aacctaagtt
     4741 actacagcaa gtattggaag ctattattac agaagataat gatgaaatga aaacaattgg
     4801 tatttacctg atcagtctgg ctttgctagg attagccgca ggtgtaacga acacgatttt
     4861 ctctgcaaaa gtagctcaag gcgtaagtgc agatatccga gaagaagcat ttcgaaagat
     4921 ccagacattt tcatttggaa atatcgaaca gttctctgct ggaaatcttg ttgttcgtct
     4981 aacaaatgat atcacgcaaa tccaaaattt agtgatgatt tctttgcaat cactttttcg
     5041 aattccattc ttatttattg gtgccttcat tttagctatg atcacgatgc cgcaattatg
     5101 gtggatcatc gtagcgctta tcgttacggt atttctgatt acggcacttt catttacaag
     5161 gatgggcaag cacttcatga tcattcaaaa actgattgat cgtgtgaata gcattgcaaa
     5221 agaaaactta ctagggattc gtgtagtgaa atcttttgta caagaagaaa accaattgaa
     5281 gtcattcagc aaagtaagtg aggacttaac aaaacacaac atcatagtcg gtacattatt
     5341 ttctgtgatg atcccgtcct tcatgctggc tgccaatttg gctgtggttg gggcgatctt
     5401 ttttgtgagc gatcttgtta aagatgatcc tacgttaatt ggtggaattg cttcattcat
     5461 gaactacttg atgcagatta tgatggcaat cattattggc ggaatgatga tgatgatgac
     5521 ttcaagagca gccgtatcgc tgaagcggat tgcggaaatt ttagatgctg aaccagatct
     5581 tacttattta gacgttccag aacaagagtt gacgggttct gtcacttttg accatgtttc
     5641 ttttcgttat cctggtgagg atacagatac gcttaaagat atcagctttt ctatcaaacc
     5701 tggagaaatg gttggtatcg tcggggcgac tggtgccggg aagtcaacac tagcacaatt
     5761 gatccctcgt ctatttgatc cgacagaagg caaagttgaa gtaggtggtg tagatcttcg
     5821 tcaagtaaat gaaaagagtt taagacaaac ggtttccttt gttttgcaaa aagcaatttt
     5881 attctcagga acgattgctc aaaacttgcg ccaagggaaa aagaatgcaa cagaaaaaga
     5941 gatggaacat gcttcttcta ttgctcaagc aaaagaattc atcgaaaagt tatctgatcg
     6001 ttacgaagca ccaatagaag aacgtagcag taacttttct ggtggtcaaa agcaacgttt
     6061 atccattact cgtggcgtta tcggtaatcc aaagatcttg atcctagatg acagtacgag
     6121 tgcactggat gctcgctctg aaaagctggt ccgagaagca ctcgatcgag atttgaaggg
     6181 aacaacgacg attgtcatcg cacaaaaaat tgcttctgtt gtcaaagcag accgcatctt
     6241 agtattggat gaaggcagat tagtcggcga aggaacccat gaggaattgg tagctggaaa
     6301 ccgtgtctat caggaaatct ttgaaactca aaaaggaacg gaggagtaag tatgactgat
     6361 ctaataaaag caagtaaatt tttctatcac tatttgaagc ggtacaaact ctcctttttc
     6421 tttatcttta tcacagtgat cattgctacc tatctacaag taaaggcacc tcaatacatc
     6481 ggggaagctt ttcaagaatt agctaattac gtaggaggct tgatgcaagg cgtagacgat
     6541 aaaagcaaat ttgtttctgt aatatggaaa ctcttgctgt tttatgtact agctagtgca
     6601 gccaacttta tctatagtat tttgttcaca caagtagtag ggaagtcaac gaaccgaatg
     6661 cgtatcggtc tattcaacaa attggaaaaa ttgacgatcc gtttctttga ttctcatcaa
     6721 gacggtgaaa ttttaagtcg ttttaccagt gacttagata atattcaaaa tagtttgaac
     6781 caagctttgc ttcaagtcat cacgaatgct gttttacttg tcgggatctt gatcatgatg
     6841 ttccgccaaa atgtagagtt agcttgggct acaattgctt ccactccagt agccgttttg
     6901 atagctgtct tgattatccg caaagcacgg aaatatgtgg atcttcagca agatgaagtg
     6961 gggaaactaa atggttatat ggatgaaaaa atcagcggac aacgtgtcat catcacaaat
     7021 ggcttacaag aagaaacgat tgaaggattc ttagagcata atcaaagtgt tcgcgaagca
     7081 accttcaaag gacaagctta ttctggtcta ctatttccga tgatgcaagg aatgtcactg
     7141 gtcaatacag cgatagttat ctttttcggc ggctggttag cattaaatgg tgatttggaa
     7201 cgttcggtgg cattaggctt agttgtgaca ttcgtccagt attcacaaca atattaccaa
     7261 ccactgatgc agatttcatc tggatacagc atgatccaat tagcgattac aggggcaaga
     7321 cgattgaatg aaatatttga tgaaaaagat gaagtcaaac cagaaaacgg taaagcattt
     7381 gatggtgttg aaaaaggtct tgcgttgcag cacgtagatt ttggttattc tccagaaaaa
     7441 ctagtcttga aagatgtctc gatcaatgtg gacaaaggag aaatggttgc tcttgttggt
     7501 ccaacaggat cggggaaaac gacgatcatg aatctgctaa accgttttta cgatgtcaat
     7561 gatggttcag tagtcatcga tggaatagat atccgagatt atgatcttga tgcattacgt
     7621 agacatgtag gaatcgtttt gcaagaatct gtattgttct ccggaacgat caaagacaat
     7681 atcacattcg gcaaaccgga cgcttcagat gaagaagtca tcaatgcagc aaaacaagcg
     7741 aatattcatg acttcatcat gacgttagaa aaaggttatg atacagagat atccgaagaa
     7801 aataacttat tcagtacagg tcaaaagcag ttgatcagta ttgctcgaac gatcatcaca
     7861 aatccatctt tattgatttt ggatgaagca acaagtaatg tagacacggt aacagaagca
     7921 aggatccaaa aagcaatgga tgaagcaatc aaaggaagaa ccagctttgt gattgctcac
     7981 cggctgaaaa caatcttgaa tgcagataga atcgttgtct tgcgtgatgg ggaagtcatt
     8041 gaagaaggca gtcatcatga gttattagca gaaaatggat tttatgcgga actttatcat
     8101 aatcaatttg tatttgaaag ttaaattaaa agaacctcgt tataacgggg ttctttttat
     8161 atattttatg ttgtttgttt ttataagggg ca
//
LOCUS       DAKCAA010000091         8122 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000091 DAKCAA010000000
VERSION     DAKCAA010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8122
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.093"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(59..1042)
                     /gene="istA"
                     /locus_tag="OUE31_002481"
                     /pseudo
     CDS             complement(59..1042)
                     /gene="istA"
                     /locus_tag="OUE31_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1437..2279)
                     /locus_tag="OUE31_002482"
     CDS             complement(1437..2279)
                     /locus_tag="OUE31_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCU0223451.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2598..2789
                     /locus_tag="OUE31_002483"
                     /pseudo
     CDS             2598..2789
                     /locus_tag="OUE31_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349346.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
     gene            2780..3238
                     /locus_tag="OUE31_002484"
                     /pseudo
     CDS             2780..3238
                     /locus_tag="OUE31_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose 1,6-diphosphate aldolase"
     gene            3266..3583
                     /locus_tag="OUE31_002485"
     CDS             3266..3583
                     /locus_tag="OUE31_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCU0223452.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            3583..5289
                     /locus_tag="OUE31_002486"
     CDS             3583..5289
                     /locus_tag="OUE31_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCU0223453.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            5431..6837
                     /gene="lacG"
                     /locus_tag="OUE31_002487"
     CDS             5431..6837
                     /gene="lacG"
                     /locus_tag="OUE31_002487"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCU0223454.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRLKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            6960..7133
                     /locus_tag="OUE31_002488"
     CDS             6960..7133
                     /locus_tag="OUE31_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HCU0223455.1"
                     /translation="MKLPSLLKCGKWYVLTGKEWICHSDLELSAFEWEFLQSLDVEIR
                     ETIHFEVNYLPFQ"
     gene            7154..8053
                     /locus_tag="OUE31_002489"
     CDS             7154..8053
                     /locus_tag="OUE31_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCU0223456.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDEDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSSLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         2413 a         1482 c         1612 g         2615 t
ORIGIN      
        1 aataaatagt ttttctatca agtatattga actacgataa atttgttatt ttgttttgtt
       61 taatttcgtt gtacttattg gctttgactt cgatttcttt aaatactggg taatcggtgt
      121 ccggcaaagc tagcaaatct gttttttctg tgttccatag atcattgata atgacatgtt
      181 tttcgtaatg gattcgctct cgatcgtgtg acagctccac cgctaatgcc tcgttgaaac
      241 tggcgaaatc cttcataatc ggtgtagatg aaaagaagtt gtaccgtaca tagccgactt
      301 tgttttccat actacctttc tcgtttccgc tacgtggatt gcacacctgt gtctcaaaac
      361 catagtgcat agaaaatcgg aggaaaccgt cagtcagcac cgcttgttca gtctttgttt
      421 ttgtctaagt aacggccgtt gacatattat caatccgtat tttccgagga acgccacctg
      481 attggctgaa gagttctttc atgccttcca acaaacattc ttgattctcg gcggggagta
      541 caacggcgaa tcctgcatta ctaaaaggga aagtcatcac taataccttc acatctttaa
      601 acgctccatc gtgacaaact tccatcgtac caaaatcaag ttgcgcttct gctggcgggt
      661 gttcaagacg ctcaaagcct tggtcttcca gtgtttccaa gtagtgtgtc gctttccaat
      721 cttgaatgaa tacacagact gttcggtagg atcctggaaa gccatcggct tttaaagcag
      781 tagtcattgc ttcagcagtc ctacgctttt tatttggcag cttagcatct tctgaaagcc
      841 atagggaaac gatgcctccc cacttttctg tatacatcat accagtcttt ttgcgtgctt
      901 taggttgcgg cagcaaatca tcatctgcat attttttagc cgtgcgccaa tttacatcta
      961 gctcctttgc aatatgatta atggatttat catgattatt tcgtaaattt ctgatagtat
     1021 taatatcggt cattgtgagc atacctttct tacctccagt tacagtgtcg agactataac
     1081 tttagaggag tttcaggttg cccgcaatgg ctttttatct taacttaatc gatttgcgga
     1141 gttgtgtagt ttttcgttgc acttgtatgt acttttattc tgccataaac agcttaatga
     1201 atgtccactt gaaaaagtga ataaacgaaa tagatgactc gatttaataa ggaagtaaac
     1261 ccacacagaa atataggtga ttttccttga atgaccaaga tattgaaagt tagtgaaaaa
     1321 acacaaaaag gtagccctat tcacagaagg tctgcctttt gtgttatcgc cagcaaacat
     1381 tagagggggt atttcatata gcttttgtcc tctcgacagt cctatcagtt tctcttttaa
     1441 cttatctcta agtgctgtcc agttttaata gcttctagct tgtttcctaa ctgtgttttt
     1501 aatatgttga aggcttttga acctgtgcag tggcaagtaa ggattttttc tactcgtgag
     1561 tcattcaatt tatttccaat tttcattacc tcttgctcag gtagacctaa attatttata
     1621 taaggtatgc caatcatatg gaagccacca attaggtatt ttatgggttt agtcggaaat
     1681 gtttcaagag caatttccat catatcgata atgccatgat gactacagcc agtaaagaca
     1741 atcagaccgt cttcttgctc aattacgacc aataattcat ctgaaaaatc atcataaaca
     1801 aatttatcat ccatcttttt gtataaattc ttggtggtcg agtttgcttt gcctaggggg
     1861 atgatatgga agctcggagc aagttctgtt ttcgttttta ttgtatgtaa attctcatgc
     1921 attttaagga tttcattttt aggaatacca acatacagaa acgtggttaa aatctttaaa
     1981 taatggggta aagttacacc ttcagctgta taaatagggg cgtttcctga ttttaaatat
     2041 cttaacccgc cggtgtggtc agaatgaccg tgtgaaataa tcactgcctc cagatcattc
     2101 aaagtttccc ccattttagt cgcattatag actaattttt tattagcgcc agcatcgaag
     2161 agatatttct tccctgagta gttaattaag agagataacc catgtccact tttaaagttc
     2221 aaatttattc ttgagttttc aaataaaacc ttgatttcca ctataacatc tcctttcaca
     2281 tgaacgtgta ttcatatatt gtagcacatt aagttctatt ttttgttgta attaccgaaa
     2341 aaaatattaa tggacgcttt ttacgcttta tttcgtatgt ggaagaaaat ttcttaggat
     2401 gtggcggggg attggggcaa agctaaattc caattacagt gatcatttaa ttagacacct
     2461 ttaaataccc acactttcat caacactata atttagggaa agaaaagtgt tggcatgata
     2521 tagaaaaacc tttaattaac agcgtttcct aaaattggca cgcatcttgc ttatagaaaa
     2581 gcgtaaggat aggaggaatg aaaatggcaa ctataattct tgccagccat ggggaatttg
     2641 ctcaaggatt aaagcaaaca gcgacaatga ttattggaga tagtgtacca attcatgcct
     2701 tgtcagcatt tagagatgaa gatgaatcta ttttggtaca aataaaaaaa cttttagcca
     2761 caatagatat agaagaaacg gttctgttga atatgcaaaa gtgaaacctc gcaaagtcat
     2821 tgaagcgatg aaagttttct ctgatccacg ctttaacatt gatgttctta aagtagaagt
     2881 accagttaac gttaaatatg tcgaaggttt tgctgatggt gaagtggttt acagtaaagc
     2941 tgaagctgct gacttcttta aagcacaaga agaagcgact aaccttccat acatctacct
     3001 aagtgcaggt gtatctgcta aattgttcca agaaacattg caatttgctc acgactcagg
     3061 tgccaagttt aatggtgtgc tttgtggacg tgctacttgg gcaggatctg tagaacctta
     3121 catcaaagaa ggtgaaaaag cagcacgtga atggttgcgt actactggat tcgaaaatat
     3181 tgatgaactt aacaaagttc ttgttaaaac agctagtcca tggactgata aagtatagta
     3241 aaaacataaa acggaggata ttgttatgaa cagagaagag atgactctct tagggtttga
     3301 aattgttgct tatgctggag atgctcgctc taaactttta gaagcgctta aagcggctga
     3361 aaatggtgat ttcgctaagg cagatagtct tgtagtagaa gcaggaagct gtattgcaga
     3421 ggctcacaat tctcagacag ctatgttggc tcgagaagct tctggggagg aacttccata
     3481 cagcgttacc atgatgcatg gtcaggacca cttaatgact actgtcttat taaaagatgt
     3541 gattcatcac ctcatcgaac tttataaaag aggagcaaaa taatgcataa actcattgaa
     3601 cttattgaga aagggaaacc gttctttgag aaaatctctc gaaacatcta tcttcgtgct
     3661 attcgtgatg gatttatcgc tggtatgcca gtcatccttt tctcatctat ctttatcctt
     3721 attgcctatg tcccaaatgc ttggggattc cactggtcaa aagacattga gaccttcttg
     3781 atgactcctt atagctattc gatgggtatc ctagcattct ttgttggtgg tactaccgct
     3841 aaagctttga cggactcaat gaaccgtgac ctacctgcga ccaatcagat taacttctta
     3901 tctacgatgc tagcgtctat ggtagggttc cttttgatgg cagctgagcc tgcaaaagaa
     3961 ggaggcttct tgacagcctt cacgggaaca aaaggtcttt tgacagcatt tattgcagcc
     4021 tttgtgacag ttaatgttta caaggtctgt gtgaaaaata atgttactat tcgtatgcct
     4081 gaagaggttc caccaaatat ctctcaagta tttaaagact tgattccatt cactgtagcg
     4141 gttgttctcc tttatggatt tgaactcatt gttaagggaa ctcttggtgt aaccgttgca
     4201 gaatcaatcg gtacccttct tgctcctctc ttctcagctg cagatggtta ccttggaatt
     4261 acacttatct ttggtgctta tgccttcttc tggtttgttg gtatccacgg tccttcaatt
     4321 gtcgaaccag caatcgctgc tatcacttat gccaatatcg atgccaactt gcatcttatc
     4381 caagctggac aacatgcaga taaagttatc acttctggta ctcaaatgtt tattgttacc
     4441 atgggtggaa caggagctac attgattgtt ccattcttgt tcatgtggat ttgtaaatca
     4501 gaacgtaacc gtgccatcgg acgtgcctca gttgttccaa cattctttgg ggttaatgag
     4561 ccaatcttat ttggtgcacc aatcgtattg aatccgattt tctttgtacc gttcattttc
     4621 gctccgattg tcaacgtttg gatctttaaa ttctttgttg acacattgaa catgaactca
     4681 ttctctgcca accttccatg ggttactcct ggtccgttgg gaattgtact cggtactaac
     4741 ttccaagttc tatcatttat cttagccgga ctcttggtag ttgttgatac tatcatttat
     4801 tacccatttg ttaaggtata cgatgaacaa attcttgaag aagaacgttc tggtaaaaca
     4861 aacgatgctc ttaaagaaaa agtagctgca aacttcaata ctgctaaagc agatgccgtt
     4921 cttggaaaag caggcgttgc taaagaagat gtagcagcaa acaataatat cacaaaagaa
     4981 actaatgtcc ttgttctttg tgcaggtgga ggtacaagtg gcttgcttgc caatgccttg
     5041 aacaaagcag cagcagaata caatgttcca gtcaaagcgg cagcgggtag ttacggtgct
     5101 caccgtgaaa tgttgccaga gtttgacttg gttatcttgg ctccgcaggt cgcttcaaac
     5161 ttcgatgata tgaaggctga aacggataaa ttgggcatta aacttgcaaa aactgaagga
     5221 gctcaatata tcaaattgac acgtgatgga caaggtgctc ttgcatttgt tcaacaacag
     5281 tttgattaat aaatttgtaa aagttatttg agacgagatt attctttcag ttccttataa
     5341 tattgttaac catatcattg catttcattt ccttggtttc cggaactcag aatatcgtct
     5401 caaatgcttt ttttgaaagg atttatagtt atgactaaaa cacttcctaa agattttatt
     5461 tttggtggtg ctacagctgc ttatcaagca gaaggtgcga ctcacacgga tggtaaaggc
     5521 ccagttgcat gggataagta tcttgaagac aattattggt acacagcaga gcctgcaagt
     5581 gatttttacc ataaatatcc tgttgattta gaattagctg aaaaatatgg cgttaatggt
     5641 attcgtattt caattgcctg gtctcgtatt ttcccaactg gctatggcga agtaaatgaa
     5701 aaaggtgttg aattctacca taatcttttt gccgagtgcc acaaacgtca tgttgagcca
     5761 ttcgtgactt tgcaccactt tgacacacca gaagttcttc actcagatgg agatttctta
     5821 aaccgcgaaa atatagaaca ctttgtagat tatgccgctt tctgttttga agagttccca
     5881 gaagtaaact actggacaac tttcaatgaa attggcccaa ttggagatgg tcaatacttg
     5941 gttggtaaat tccctccagg cattcaatat gatcttgcca aagtcttcca atcacaccac
     6001 aatatgatgg tttctcatgc acgtgctgtg aaattgtata aagataaagg ttataaaggc
     6061 gaaattggtg tagtacatgc gttgccaacc aaataccctt atgatccaga aaatccagca
     6121 gatgttcgtg ccgctgagtt agaagatatc atccataaca aatttatctt ggatgcaacc
     6181 taccttggac actattcaga taaaacgatg gaaggggtca accacatcct agctgaaaat
     6241 ggtggagaac ttgatcttcg tgatgaagac ttccaagcac ttgaagcagc taaagatttg
     6301 aacgatttcc ttggtatcaa ctactacatg agtgattgga tgcaagcctt tgatggtgag
     6361 actgaaatca ttcacaatgg taagggtgaa aaaggaagtt ctaagtacca gattaaaggt
     6421 gttggtcgcc gaatcgcacc agattatgtg cctagaacgg attgggactg gattatttat
     6481 cctgaaggct tgtatgacca aatcatgcga ttgaaaaatg attatccaaa ctacaagaag
     6541 atttacatca ctgaaaacgg tcttggatac aaagatgagt ttgtagataa taccgtttat
     6601 gatgatggtc gtattgatta cgtgaagaaa cacttggaag ttttatcaga cgcaattgcg
     6661 gatggtgcaa atgttaaagg ttacttcatc tggtcactta tggatgtctt ctcatggtca
     6721 aacggatacg aaaaacgtta tggactattc tatgtagact ttgacacgca agaacgctat
     6781 cctaagaaat cagctcattg gtataagaaa gtagcagaaa ctcaagtgat agagtaatat
     6841 tacttgaaaa tgtaaaaaat tgttatccga tactttagaa aaagtacaac acttatttag
     6901 accaggcttt gaaaaggtat atattgttag tttcgaagat tgtcctatga ttcctgagct
     6961 tgaagctacc ctcgttgcta aaatgtggta aatggtatgt tttaactgga aaagagtgga
     7021 tttgccattc tgatttagag ttatcagcat ttgaatggga atttttacaa tcactcgatg
     7081 tagaaatacg tgagactatt cacttcgagg taaattattt gcctttccaa taataaaaag
     7141 aaaggaatta gttgtgacta tcgaattaaa aaacgagtat cttactgttc agtttaaaac
     7201 acttggtggt caactgactt cgattaaaga cgaggatggg atagagtatc tctggcaagc
     7261 tgatccaaat tattggaatg gacaggcgcc tattctattt cctatctgtg gtagtttacg
     7321 aaatgattgg gctatttata gacctcaaga aagacctttt tttacaggtc ttattcgtag
     7381 acatggtttt gttcgaaaag aagaatttat tctggaagaa gtcaatgata atagcgtgac
     7441 ctttagtatt aaaccaaatg ctgagatgct tgataattac ctatatcagt ttgaactgag
     7501 agttgtttat accttgaatg gtaaatcaat tagaaccgaa tttcaggtaa cgaacttgga
     7561 aatggaaaaa acaatgcctt actttattgg agcccatcca gcattcaata gttctttagt
     7621 agaaggtgaa aactatgagg attattatat tgaatttagt gaggttgagt cttgctcgat
     7681 accaaagagt tttcctgaga caggattatt agatttgcaa gatcggacac cttttttgga
     7741 aaatcaaaaa attctcgatt tggactactc acttttttcc catgatgcca ttacacttga
     7801 ccagctcaag tctcgtagcg taacgcttcg gtcaaggaag tctggtaaag gtcttcgagt
     7861 agattttgat gattttccga acttgattct gtggtctaca actaataaaa gtccattcat
     7921 tgctttggaa ccttggagtg gtctctccac ttcacttgaa gaaggtaatt tcttagaaga
     7981 taaaagacag gtaacgaaaa tttcacctca agaaacttct agaaaaatct atgatattac
     8041 tatccttaat taaaatttgt tattatttga gtcttcaata agatttgaat actcttacct
     8101 tgtgatgata gattggtctt ct
//
LOCUS       DAKCAA010000092         7633 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000092 DAKCAA010000000
VERSION     DAKCAA010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.094"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(14..706)
                     /locus_tag="OUE31_002490"
     CDS             complement(14..706)
                     /locus_tag="OUE31_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCU0223457.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1143..1712)
                     /locus_tag="OUE31_002491"
     CDS             complement(1143..1712)
                     /locus_tag="OUE31_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCU0223458.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="OUE31_002492"
     CDS             complement(1786..2109)
                     /locus_tag="OUE31_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223459.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="OUE31_002493"
     CDS             complement(2263..3075)
                     /locus_tag="OUE31_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223460.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSELYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="OUE31_002494"
     CDS             3429..4277
                     /locus_tag="OUE31_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HCU0223461.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQELVPFVFSHRLIFYDRSLKEDEKTQMIHALVAQ
                     IPIPVR"
     gene            4281..5354
                     /locus_tag="OUE31_002495"
     CDS             4281..5354
                     /locus_tag="OUE31_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HCU0223462.1"
                     /translation="MEKAKDYFINFVLFLIYFVIVFFALVFNNSLGWFLLAFFTLYVS
                     WSVFSLSTFLKKLSVTCTVQPVVYRKKSIQVSFSIAKKRAFSFPLPRLQIVFPEIFAE
                     KKQEILILTNKPQEVQVLWQPKERGFHEALTVIFTAYDSLGLFRKRTRRELSFPVTVL
                     PAFHKSQAEALQRVLEKKQQLNAYQKGLDFREHRSYRPGDSFNRIDWKLSAHSQEWLY
                     REYEYQEEEYSPLLCFWGSPSLKFDHLLDLYFSLWHLRKEKQPELLILGDRTFHGKDP
                     GYTYFASLNAGDEKTFLAHLKKQAKKQIVLFIPAHSPEVSEAVETLSKDRTVYLVYFA
                     EKQIMIQEKDKVCSLPGGEWIDD"
     gene            5344..7514
                     /locus_tag="OUE31_002496"
                     /pseudo
     CDS             5344..7514
                     /locus_tag="OUE31_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342468.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2257 a         1533 c         1396 g         2447 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acctatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtgtgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataaag ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagcct atgcgttgat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggag ttagttcctt tcgttttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagacac aaatgatcca tgcccttgtt gcacaaatcc
     4261 caattcccgt gaggtagata atggaaaaag ccaaagatta tttcattaat tttgtgttat
     4321 ttctgatata tttcgtcatt gtcttttttg ctcttgtatt caacaattct ttagggtggt
     4381 tcttattggc cttttttact ctttatgtat catggagtgt gttttcatta agcacctttc
     4441 taaagaaact ttctgttact tgcacagtcc agccagtcgt ttatcgtaaa aaaagtatac
     4501 aggttagttt ttctatagcc aaaaagagag ctttttcttt ccctctccct cgtttacaga
     4561 tcgtctttcc agagatcttt gcagaaaaaa aacaagaaat attgatcctt acaaataaac
     4621 cgcaagaagt ccaagtactt tggcaaccaa aagagagagg gttccatgaa gcattaaccg
     4681 tcatttttac agcctatgat agtctaggac tttttagaaa aaggacaaga agagagcttt
     4741 cttttcctgt gactgttctt ccagcttttc ataagtctca agcagaagca ttgcaaagag
     4801 ttctggaaaa aaaacaacag ctgaacgcgt atcaaaaagg tcttgatttt cgagaacatc
     4861 gctcttatcg ccccggcgat tcttttaacc gaatcgattg gaaattgtct gctcatagtc
     4921 aagaatggtt ataccgcgaa tacgagtatc aagaagaaga atattctccg cttctttgct
     4981 tttggggttc acctagcttg aaatttgacc atctgctaga tttgtatttt tctttatggc
     5041 atctgagaaa agaaaagcag ccggaacttc tgatattagg cgaccgtacc tttcatggca
     5101 aagatcctgg atatacctat tttgcttctt tgaacgctgg agatgagaaa acttttttgg
     5161 cacacttgaa aaaacaggca aaaaaacaaa tcgtcctctt tattcctgcg cattctcctg
     5221 aagtctcaga agctgtcgaa acattgtcga aagatcgaac agtctatctt gtttatttcg
     5281 cagaaaaaca aatcatgatc caagaaaaag acaaggtatg ttcactgcca ggaggtgaat
     5341 ggattgacga ttaaatggga aaaatacctg cgcggcgttt actcctttat gatactaagt
     5401 gtaggtgctc cgatatttgt agcagctaat caattgcaaa acagctcccc tcttatccta
     5461 actattggta tcctatgtct tattgtctgc tgtatttcta aaaaatgggt acgattgctg
     5521 ctttctttgc cagtaatgat tggctgtttg tttgcctatt ttccttcaaa gacattttct
     5581 ttattatggg tcgtacagtt tttttcgtca gttacagagg aattcttcca tctatcccaa
     5641 ggtaaacttc attatttacc agaaaagaca gctttttttc tcatattgtt gttgatctat
     5701 ttatttatta ctttgaccgt ggattacgac tattggtatg caccctttct tgcgttgatg
     5761 gcttacttca tgatgcttac cgtttttcgg gaaaaagaac tattgtacga aatgattgcg
     5821 gtagtagctg ttttatgcgt acatttggca gcaaggcaat ttttcgccat ccgattgttg
     5881 tcgggaaacg ctcgattcca gtcgtttact acgatcctgc ttatttgttt gttcactttc
     5941 agcgccatct tgcctttata tctcccaaaa gtacaccaat ctcttgagga aacgagtgaa
     6001 ccgatccgag aatatcttaa tgatgaaggg ctttatgata cactccatga gtaccgatta
     6061 accggaagtg ccagaacggg tttcagtgaa aatgatgaac aacttggtgg tccattgtat
     6121 gataatggtg aagttgtttt tacagcgaac cagaaagtaa acggctattg gaagatagaa
     6181 aataagaatc attacaccgg ttctggatgg gtagaagatc cggatgcacc catccaacca
     6241 atccaagaat ttcctgttga tatcacaagc taccaaacag ttatggaaga aaaagaaaac
     6301 attacattga cgctaaaaaa ccaagctttc ttaccttatc cttatggaaa tactaccttg
     6361 actgattttt cattagccag tggacaaacg ctttactatt tgcctgaaag ccaacgattc
     6421 atccctgtcc caaatgaatc gacgcgattg gcgtccttac aaacagaaag attagctttt
     6481 acgagagaag aattaaaaag cagtcagtta gaggccgatg atttagaaaa tcaacagaca
     6541 aatcttcagt tgccgaaagg gttgcctcaa cgcattgagg acttggcgat cgaattgacc
     6601 aaaaatgaag caactttaat tcgtaaagtc gaagctgtcg aacagtattt gaaaacaagc
     6661 gggaattttc gctattccaa aacggatacc ggacatacgc ctaaagaacg cgattatgta
     6721 gattatttcc tcttcgattc aaaagtcggc tattgtgaca acttttcaac ttctatggtc
     6781 gtccttcttc gcacactagg catccctgct cggtggacaa aaggttttac ggatgggatt
     6841 agaacaggta cagatgagca aggaaatgag gaatacagca ttctcaatag tcatgctcat
     6901 tcttggccag aggtgtactt tcctgggttt ggctggcttc catttgaacc aaccccttca
     6961 tttgccaatc caactgtttc acaaccagcc gctgaaacaa cagaaaccgt ccaatctgct
     7021 gaagaacaac caaaagaaag cgaaaatata gcagaaacta ttaccagtga gagacctgcg
     7081 actatttcgt cagataacac gacactcaca ccgtcttata aaatcgtctt attcagcctt
     7141 ggggtgtgtt tatccgtctt gttgttcttt ctattgttat ttagaaaatc tctgcgctgg
     7201 acaagttatc ttatctatct tcattttttt gcttctacta atgcggttgc gtatcaaaaa
     7261 cttcttcacc atttggaaac actggtaccg cgcaccctcg cagaatcttt gcaggcatac
     7321 agccaacgaa tagaacaaac attcaatcta gatcaacgtt tcattcgatt aactgctcaa
     7381 tatgaagctg aaatatatgg gcgacaagca aatccggtaa aattcgataa aaaaacctat
     7441 ttagaactaa cgcatataat aagaaaacgg tatacaaaaa ggttatgaca aaagggagca
     7501 gcttcaaaaa ataagataaa attcctggag aatctacttc tggaatgccg agaaccagct
     7561 gattgagcat cgattattcg taaaaaaaga gcgtggggca aaagtaaaga acacttttgt
     7621 ctcacgctct aaa
//
LOCUS       DAKCAA010000093         7597 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000093 DAKCAA010000000
VERSION     DAKCAA010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.095"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(940..1353)
                     /locus_tag="OUE31_002497"
     CDS             complement(940..1353)
                     /locus_tag="OUE31_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HCU0223463.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1809..2294)
                     /locus_tag="OUE31_002498"
     CDS             complement(1809..2294)
                     /locus_tag="OUE31_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223464.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2433..2648)
                     /locus_tag="OUE31_002499"
     CDS             complement(2433..2648)
                     /locus_tag="OUE31_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HCU0223465.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2872..3672
                     /locus_tag="OUE31_002500"
     CDS             2872..3672
                     /locus_tag="OUE31_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCU0223466.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3691..5559
                     /locus_tag="OUE31_002501"
     CDS             3691..5559
                     /locus_tag="OUE31_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCU0223467.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5552..6043
                     /locus_tag="OUE31_002502"
     CDS             5552..6043
                     /locus_tag="OUE31_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCU0223468.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6031..6585
                     /gene="srlA"
                     /locus_tag="OUE31_002503"
     CDS             6031..6585
                     /gene="srlA"
                     /locus_tag="OUE31_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HCU0223469.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6603..>7597
                     /locus_tag="OUE31_002504"
     CDS             6603..>7597
                     /locus_tag="OUE31_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HCU0223470.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2234 t
ORIGIN      
        1 gttactatga ataacataat aagaaagtaa agtggattga tttgagatct ttttatactt
       61 caaaaaagat aacacccaac tttcaaaaat atgttttgga agttgggaca aacgagttaa
      121 tacattttaa tacattattt tttattcaaa aaaaatagca caatggcaaa gatcgtaaga
      181 gagatcataa gccccaatga atgactaaaa agaaaagcag aatcacatgc catatcatcc
      241 catatttctt caagaaaata aataagcggg aaaaagggaa ggaatagtag aacatcgatc
      301 cagcaccatt tttttcttct tttgaaataa cataaaacaa taaacatgaa cgtgcaggga
      361 agtaaaaaca aagctttact cataactaac aaaataccag ctccttttat ttttttctcc
      421 cccacattca aagagtaaca atggtatgta cttaataata gaaaaatgga tcaacttgta
      481 tgaataacag ctgaaaagat ctgcaccaaa taaaaaactt ccagccaaaa ctgactggaa
      541 gtttattttt ttctgaaata ttctaacaca aatatgaaaa agatggccga agctaataag
      601 ccgatttcgt agcaaaacaa tgagatacca gagtcgtaat aataaaatcc tctaatctta
      661 tggataaaat agatcatcgg acaagcagat aagagtaagt atttgttagg ccttttgaat
      721 aagtaaaaga aagcactggt cattatgata aatggtatcc aaaacaaaag tttacttaag
      781 acaatcaaat gatcaactcc catatttttt accaagagag atcataacat ctttatcgta
      841 aaaacaaaat atttttttgc tcattttgaa aatttaaaca tactcgttct tatccaaata
      901 tataaaaatc gcccctcatt catcgagagg cgataagttc taatttaact caattttttt
      961 tgtttctttt ggctgataag ctgttttagg taataccaat ttcagcacac cgtttttaaa
     1021 ggttccagtg attttttctt catcaacatt aggaagatag aatgaacgtt tgtaagagac
     1081 cgaatgtctt tctttccgta catagttgcc atcttcttta tcttctgtat gggactcatg
     1141 attggcggag atcgtcaaag tattatctga atattcaact gtcgtgtctt ctttgtcaca
     1201 gccaggcata tcagcagtta gtttgtattc tttttcattt tcgactaaat ctacttttgg
     1261 ataacttgaa acacctaaaa aatcattgaa tgctggacta aacacgtcat tgaaatcagg
     1321 gaacatgtcg cgaatgctag gtacatttgc catttttgat catcctttca ataagtattt
     1381 tttatttatc cctatttacg taataactct attttgaaaa aaatgcaagt ataatggtta
     1441 gctttgtgaa tatttcatct aatacgatac aaaggctatc tttctaattt gaaaaaggga
     1501 tcattaaaat aataagaaga aaatatgtca aaaggtaaaa aagtaaattc ttctatccaa
     1561 atatagaaaa attgaatcta gaaaaccgcc cgacaataaa tttcattaac tcagttgacc
     1621 gaaaatgaag tagataccaa aaatttatca agagagcaag tagagaagtg agtatattca
     1681 taagagaaat agctgtaacg aattattagg ttaatgcaaa tgcttattta tactccgtat
     1741 aactttctca gaaaaaatga taccaataat gacttgctag tactgtaaat ccgtataata
     1801 tcatctaatc aaaatggtgt tccatttgca tctgtcatcg taatcgatcc ttcgggtgac
     1861 actcgataaa aaccaacgct tccagatcct ccttgggaac ggatttgttt gctggaagct
     1921 gtgaacaaat aatctcgatc aattttttga taaaagctaa taacaatatc gtcactttgt
     1981 aattcggaac ggtgggcaat aagaaataga agtgctttgt cagagttttc taatggaaga
     2041 gaaggtacag tgctttcttg catttcagat gttgaagaaa tgctaaacga ctgaatactt
     2101 gattggctat gttgcgaatc tacattacca gtagaagtat tagtaatgga agtagtagaa
     2161 gtacttttag ttgaaccaac ctcagttgtt gaaatggctg ctgaagattc tttaacagaa
     2221 ttctttgttt tatatccaca ggcagaaaaa agtattacag ttcccaacaa gcctgcgtaa
     2281 atccctttat gcatgatagc tcctcctaaa atagattatc tttattcagt atatcactta
     2341 aacaaagaaa agcagatggt ttaaaatgaa aaaaccttcc caataaaggg aaggttcatg
     2401 aagataataa cttttttaat aattatagct ttctaatatc tttcatcaac ttttctagta
     2461 atcattggga aaaatttcaa gcagtagatc gcacaaatac ctacgacgat ataaatgatc
     2521 ttcgcaaaaa tagttgttga accaccagca atcatagcta ctaaatcaag ttcgaacaag
     2581 cctaccaaca gccagttcaa ccctcccaca atcaataaag ttaatgcaat agcatctaaa
     2641 gttttcatta gaattctcct ttcttaaatg ataaaacaat tatatatcaa aaagagaaac
     2701 attgcttata taacgctcag gaattttagc aatctatgca aaaagatgaa aatttttttt
     2761 gctcttccat tagtacacat tttttagctg aagctgtaaa tttcatgtct taattttttt
     2821 tagtgagctt ttatactgga tttgtaagaa aaaagaagga gaggatcaca tatgtcggat
     2881 tggttggata ttgcaggaaa agtagtaatt gtaactggag gttcctcagg aattggaaga
     2941 agtatcgtcg aaaatttgtt gaagcagaat gcacaagtag cgaattttga tgtaactgaa
     3001 tgccgtatac agcatgaaaa cctactatct ttaaaagtcg atgtgtcttc taaaacggac
     3061 atagaagaag ggatatataa agtaatgaaa catttcaaga cgatcgatgg tctagtcaat
     3121 aatgcaggaa taaatattcc ttctcttcta atagatagaa atcatccaaa aagcaagtat
     3181 gaattatcag aacaagtttt tgataagatg atcgctgtca atcaaaaaag tgtatatttg
     3241 atgagccaag cagttggaag aatcttggtg caaaagggat caggagtgat cgtgaatctt
     3301 tcttctgaat caggattgga aggatcagaa ggacagagct gttatgctgc tacaaaagca
     3361 gcgatgaaca gttttactcg ttcttgggca aaagagttag gaaagaggaa tgttcgtgtg
     3421 gtaggtgttg caccagggat actggaagaa accggtttga gaacacaaga atatgaagaa
     3481 gctctttctt atacgagagg tataagcgtc gaacagctga gaaacggtta cagtcgaaca
     3541 agtacgatcc ctctaggaag gagtggtaag ctgcaagaag tggcggatct agtctgctat
     3601 tatctttcag aaagatcaag ttatatcact ggagtcacga ctaatatttc aggaggtaaa
     3661 acaagaggat aaaggatagg ggggacgcac gtgacgctag taaacagatg gtaccaatta
     3721 ttgaaattac tagtcactca caagaaagtt tcaatccagg aagtgcaaaa agaaatcaaa
     3781 accagtaatc aaaccataaa aaaagatatt ggggagttga atgaagaaat tgccggtatt
     3841 gcaaaaatca tccaaaaaaa caaacatttt gaacttgaaa tttatgattt tgattttttt
     3901 gatgagatca tgcaaggaaa attgaaaaca gccagtgatt tcaattcggc atccaaaaga
     3961 atcgcttatt tactaaatag gctgatcgaa acagaggatt tcttacgtat ggatgatttg
     4021 tctgaagaag tcggtgtcag cagaggaaca gtggtcaagg atctaaagac attaaaagag
     4081 atgatcaatg attttgatgt aaagattaca ggcacaccaa ataaaggact aagaataata
     4141 ggagatgagc tagaattacg actactttta ttttattttg tttctcccta cttttcagag
     4201 acgaaaacag aacagtttct agaagaaaaa caagcaatca aacattttca gaagaagacg
     4261 aatgctagta aacaagaaat caccctttta acgaaagtta tcggtatttc tttgaataga
     4321 atctctagta actatctgtt gaagaagccc atcaatcgtt acagtgggtg ttttgaatat
     4381 atccaagaat tcaatgaact gatcaatcag ttggaagaaa tctatgaact aactttgagc
     4441 caatatgaaa aagattttat cagttttcct ttgaacatca tcaacacaag tataacgatg
     4501 ataaggaaag ctaactctga tttgcgctta tatttcgacc ccatgatgat gcgtattcga
     4561 cgattagatc tcattgatct ggatgagtcc ttcttatatc aagagatgaa acagcacctc
     4621 tctttattga taaatcgggt aatttttcgt tatcgattga ctgatttatt ttatggtgag
     4681 atagaaaaaa agtatccttt ttcttaccaa atcgctagcg aatgcataca agcattagaa
     4741 gctatcttgc aacataagat ctctaaagta gagatcagct acctaacgtt gtatttggag
     4801 ttagcatttc gatatcaaaa agagcatttt tcctctaaaa aagtagccat tgttcatacg
     4861 acaggaaaag gaacagcatt aatgatccaa agacaaatca aaaggatatt ggggagggat
     4921 atacaaataa cacatgtttc agaagaacaa tatgaaaaag tagatctaaa caaatatttc
     4981 gctgttttta caacgattcc gttaaaaaat gtaaatgaag agacaccggt gatccatttg
     5041 actaatcttt ttgatgactc ttggttaagg gcacaatggc aaaaagcaaa aaaaaagcga
     5101 ttagccgggt ttcattctac tgtttttttc tatcaaatat ggaaagaaaa aaagacgtat
     5161 caagaatatt taaacaaatt agtcgctcct ttgatcagag gctattatgt ggatgaagaa
     5221 tttgaaaaaa ggatcttgaa aagagaatat cagcaaagca catttgttaa caaagaattt
     5281 gcttttcctc acacaaccaa ccagctatct caacacattg ttttatcagt agggctaata
     5341 actgatcaag gtttagcaga aacaggagga aatggagtta tttttttatt tgccatacct
     5401 gaagaaatga cggctgaagt tgagaatgaa ttatttgagc tatacgatat cctatttgaa
     5461 ctcataaaaa tgggaataga tgagtttatt gaattagcac cgacacaaga atcattttta
     5521 aaactaatca aaagtaaagg agagagactt catgaatgat atgtatctat tcatagtttt
     5581 cgcagcttca gcttatgtgc tgcaagcagt tatcagttgg aagcaactaa agcatttcaa
     5641 tcaaacatat agcgaactgc gaagaaaagg aaaagtagcg attggtaaac gacctgggaa
     5701 aatccgttca ggcacgattg ttatgctagc tatagacgat catgatcaag ttttagaagt
     5761 cagaaaaatg caaggggtta catctttggc aaaatttcat tcattacctg tctatgcggg
     5821 tgaagatatc cattacatcg atcgttacca tccctcagtt cgagcggaag atcgtttgac
     5881 acaagcagct ttagaaaatg ccagagaagt atacttacga atagaggcag gaaatgaaaa
     5941 aagtgaacaa ccttcattgc cttttattgc tatgctcaat aattttcgga tatggaaaag
     6001 tacgatcaaa gaaaaaagga gtgacaaacg atggatatca taacaaaatt tgctgaggga
     6061 tttatgaggc tgttccaaac aggtgcagaa acattcataa gctggatgac aggaatcgta
     6121 ccagttgtct tgatgctgat ggttgcaatg aatacgctga ttgctttttt aggtgaagac
     6181 cgagtaacga aagtagccaa attatcagcg aaaaatccgc ttactcgtta ccttgtgtta
     6241 ccgttcttat ctgcttttat gttgggaaat cctatgtcat ttacaatggc tcgtttcctt
     6301 ccagaatact acaaaccaag ctattatgct gctcaagctc aattttgtca tacgagcaat
     6361 ggtgtattcc cccatattaa tcctggagaa ttgtttgtat ggatggggat tgctcaaggg
     6421 atcgaaacct tagggctaaa ttcgatggag ctggctatcc gatacttgct tgtgggactg
     6481 ctgatgaact ttattggtgg ttggataact gattttacta ctggatttgt atgcagacag
     6541 caaggaatcg ttcttagcaa aaaagtagag ctttcagttg attagagaaa ggagagtttt
     6601 aaatgtatgg tgatattaag atcgtaagag gaaacggcgg gtatggaggt cctttgatta
     6661 ttaggccgac aaaagataaa cacaagttca tctatgtcac aggtggaggt gagaggccaa
     6721 tgatcgtaga taaaatagaa gaactgacag gtatggagtc tatcaatggg ttcaaaacat
     6781 caatacctga tagtgaaatc gcgcttgcaa tcgttgactg tggagggact cttagatgtg
     6841 gaatttatcc taaaaaaggg ataccaacca tcaatatcgt ttccacagga aaaagtggcc
     6901 cattagcaca atatatcact gaagatattt atgtttcagc agtagggtta gaacaaatac
     6961 agccactaat ggaaactgat gataacaaag aaacagtaaa tactgcatct ccagataaaa
     7021 agtacaaata tgatacttct aaaaagataa ccgagcaaaa agcagagcag caaaactgga
     7081 tagcaaaaat tggaatgggc gcgggaaaag tagttgctac attcaatcaa tcagcaagag
     7141 aagcagtaga tacgatgatc cggacagtga tcccttttat ggctttcgtt tcccttttga
     7201 ttggtgtgat acaaggttct gggatcggta atgtatttgc taacattatg gcacctttag
     7261 caggaaatgc agttggatta acaatcattg gctttatttg ttcactgcca tttttatctc
     7321 ctttgcttgg tccaggggca gttattagcc aagtgattgg aacattgatc ggtgtagaga
     7381 ttgggaaagg aaatattcct ccccaattag cattaccggc actatttgct atcaatactc
     7441 aaaatgcatg tgattttatt ccagtcggtc taggtttgga agaagcaaaa gctgagacag
     7501 tagaagtagg tgtaccatca gttctttatt caagatttct taacggcatc ccacgagtta
     7561 tcattgcttg ggtagcaagt tttggattat atagctg
//
LOCUS       DAKCAA010000094         7473 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000094 DAKCAA010000000
VERSION     DAKCAA010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.096"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            718..2268
                     /locus_tag="OUE31_002505"
     CDS             718..2268
                     /locus_tag="OUE31_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCU0223471.1"
                     /translation="MSDKNTYARRSQRHKQEPDSCENTNQLNEAVKPQTGNENKQPKI
                     PKKKSNYSKYIFALFTALILVIVVTGGYIVYTLKQQEAEAQAKYETAAKNLMASIQEE
                     QDQSGISTKIDTINDGENKCLVYRPVDENTVPFKNANQLLDELAQKQQKKHREKEVLT
                     VARIKATAISSKVNQYRIEADSFIWDRSKENFKKPDSISEKDIYIFKKTGKEITNKDL
                     FPDEGSLLGIQQVIQQSILDQAKEPEKIIDAVLTMDRISYDSKMTYTPDELTIVLPKN
                     STGTSKVTLKYKDIAPFIDTDLVSQESIKDTLPALDENKKYVALTFDDGPNNSSTLDL
                     LNILKTDNVKATFFMLGQMVDQNPDVAKQVHDEGHEVACHSYSHPQLNTLSTDELQSE
                     INKANKAIFKATGVLPRNIRPPYGAIDKKSAETIGMPIIQWDIDSQDWKSKNPRAINN
                     VVKQNVYNGAIILIHDIHPESVKAIPNMISMLKNKGYEFVTIDQLLSGKQKPLHQYFG
                     MNDERLVD"
     gene            2406..3547
                     /locus_tag="OUE31_002506"
     CDS             join(2406..2634,2634..3547)
                     /locus_tag="OUE31_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCU0223472.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            3942..4161
                     /locus_tag="OUE31_002507"
                     /pseudo
     CDS             3942..4161
                     /locus_tag="OUE31_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334252.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5173..>7473
                     /locus_tag="OUE31_002508"
     CDS             5173..>7473
                     /locus_tag="OUE31_002508"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223473.1"
                     /translation="MFYQRSEKKFKYAIKKKKGGGGAASFIIGAMFLGIGLISCPTVS
                     FASETTEINQSTEIQSTLNNSILKESNSEEKQNIDVSEDSAINKDLELASKATISESE
                     NSFGETTNNQENTNLSEDSIEVQPESIIQKEVLTDNDAIQQLEVHPHEDSDDAALVEN
                     QMTRVTEESIKSNTSQVDKDTTVLSNTTRDLVNLEDTAIENVTPQKTIKKDSISLLEE
                     NNSSSASRTLRRSVRSLDVQTGENFLEDWALPDNSNISGSLITQTGITYVGVKTDDPT
                     QLHLKMAYRAAATPASIDWIYLRVDPELTKYIEEINIKNTVNIGAQVGYQRYFEKVDT
                     NTLSNVNTFGTPTGVSDAYAQVDQKTGGIYRVLLDKFFIRIPGTNPKSRGALSGNWGV
                     FPSVPLEAERYEANIYIKLSKDVAELQQELGRDKFGVQLRLQGQSSSGVATIAKESLN
                     KNTIVDLSQEEPDENNSNWLNSPSVHTITTTYEGKQMGSDGQFSSILEGTDKSLIRVQ
                     NTIMNNLLYGTALDLGRPVSFNIEIDPQILNLVSDDDYITIWQVYRENSINHHDGGSN
                     APVMLKKNMFVDNKIKIEVNKDKAGQYGNGVYYVNAVESFMNTLSSSSFVGANFIDIP
                     VMPKSLIEDEDQLISAEIKTWFTDKKNDQERIVRNSLASSYINLFPTTINFYDYSTKD
                     TEQLLKLRESTYLVSTFGQEINGMDMGETYEISNYEFVTADPESLIITQKDGNIINLY
                     YKKLSSDAEFYEPEVEKEEVNYGETID"
BASE COUNT         2763 a         1155 c         1312 g         2243 t
ORIGIN      
        1 tactattaat tgtgattttt aaatgattga aaaatagaga ggaggaagca atacgtagaa
       61 aaaatatttt aaattggtgt aagtacaaat atgttattta cagtatttta gtttctcgta
      121 ttaagtgtta ctactatggt gaattcttta gagaattaat aaatagtctt ctttgataga
      181 ttgttaaagg gaacttaaca aagtaataag atgcataatc aaatgcacaa aaaacaaaaa
      241 aagaagtttc ttcgaataga aattctgaaa taacatcctt tcgcctaata gtgaataatt
      301 taaataaaga gaaactggct acactatcaa agcaagtgat tctgtttagc taattactaa
      361 taattaaagt attaaaatag tatgtttaat caaatagaac aagattggat aatagtttat
      421 atttttaatc ctagaccatt attggtattt caaagactac aaccatacta attaatctat
      481 cgaatggtac aatttcaaaa actaaaatca aaactagtga ttctaatgtt atcaaaactg
      541 agttgaaaat taagtagcca caatatctaa agtggtgagg aattagcgat aattactacg
      601 ccgaaagtaa aagaataata gaaaaaactt tccttaaaaa ttatctatga attcgttttc
      661 attataattg cgctgtttta ttttacttta tgatgataaa tggagggata aagtcatatg
      721 tctgacaaaa atacctatgc acgtcgtagc caacgtcaca aacaagaacc tgatagctgt
      781 gaaaatacaa atcaattgaa tgaagctgta aagccccaaa ccggaaacga aaacaaacaa
      841 ccaaaaatac cgaagaaaaa atctaattat agcaagtata tattcgcatt gtttaccgca
      901 cttattctag taattgtcgt tactggcggc tatattgttt atacattaaa acagcaagaa
      961 gcagaagctc aagccaaata tgaaactgct gcaaaaaatc tcatggcttc aatccaagaa
     1021 gagcaagacc aaagtggaat ttcaacgaaa atagatacta taaatgacgg agaaaataag
     1081 tgccttgttt accgtccagt tgatgaaaat actgttcctt tcaaaaatgc aaaccagctc
     1141 ttagacgagc ttgctcaaaa gcaacaaaaa aagcatcgtg aaaaagaagt gctcacagtt
     1201 gccagaataa aagcaacagc aatatcttct aaagttaatc aatatagaat tgaagcagat
     1261 agttttatct gggatcgcag taaggaaaat ttcaaaaagc cagatagtat ttctgagaaa
     1321 gatatctata ttttcaaaaa aactggcaaa gaaatcacaa ataaggattt gtttccagat
     1381 gaaggaagtc tcttaggtat tcaacaggtg attcagcaat ccatacttga tcaagccaaa
     1441 gaacctgaaa aaatcattga tgctgtatta acaatggata gaatttctta tgatagtaaa
     1501 atgacttata cacctgatga attgactatc gtcttaccaa aaaattcaac tggaacttct
     1561 aaagtcactc taaaatacaa agatattgcg ccattcattg atacagatct ggtttcgcaa
     1621 gaaagtataa aagatacatt acctgcatta gatgaaaata aaaagtacgt cgctcttact
     1681 tttgatgatg gtccaaataa tagctcaaca cttgatttgt tgaatatact aaaaacagat
     1741 aacgtgaaag ctactttttt catgttagga cagatggtgg atcaaaatcc agatgttgca
     1801 aaacaagtcc acgacgaggg tcatgaggta gcatgtcact cgtattctca tccacaattg
     1861 aatacacttt cgacagatga attacaaagt gaaataaata aagctaataa agcaattttc
     1921 aaggctacag gcgtcttgcc tcgcaatatc cgtccccctt atggcgctat tgacaaaaaa
     1981 agtgctgaaa caattggcat gccaattatt caatgggata ttgactcaca ggattggaaa
     2041 tcaaaaaatc ctagagcaat caataatgtt gtcaaacaga atgtttataa tggtgcaatc
     2101 atcttaatcc acgatatcca tcctgaatca gttaaagcca taccaaatat gatctccatg
     2161 ttaaaaaata aagggtacga atttgtgacg atcgatcaac tattgtcagg aaaacaaaaa
     2221 ccattgcatc aatattttgg tatgaatgat gagcgactag tagactaact gtaattagat
     2281 tgagtggtat ttgaagaaat tatatttgta gtttccttat ttgatgaaaa gtcatgttga
     2341 tgttaggatg atttcatgga cacgatttgg tagaatctaa ctactaagaa aaggacgtgt
     2401 ccacgatggc aaaagccaag aaaaaatttg atgaagactt taagaagatg atcttagatt
     2461 taaaccagtc tggccaatcg gtcgaagaac tggcagcgca atatggtatc gctacacaaa
     2521 cgatttatcg ttggaagaag cttcatacaa agaatgtagc aaccggcatg actgaggcag
     2581 aaatcctagc gatgaaaaag gaaatggccc gcatgcagga ggaaaacact atcctaaaaa
     2641 aggctttaac catattcgct caaaagtaaa aatgagtgat gtcttcgaat ttattcaatc
     2701 aaatgttcat gatcatgacg taaaacaaat gtgtaccgtt ttggaagcac cgaaatccag
     2761 ctactatgac tggaagaaaa agaaaccttc caagcgccaa tcagaaaaca aacgcttaaa
     2821 ccgcttgatt tcaggaatct actttgaaaa caagggtatc tatggtgcgc ctaaaattca
     2881 taagattctt gttggccgtg gcgagacctt gtccttaaag aaagtacaaa tactgatgag
     2941 aaaattaggc ttgcgttcag tcaccctcaa gaagtacaag cctggcaaac aagcgaaagt
     3001 taaaagtgaa ggacgtaaaa acctgttaaa ccaagatttt accactacgt cgatcaatca
     3061 aaaatgggtg acagatatta cctatattca taccctaaaa gatggctgga cctacctctc
     3121 cactattcaa gacctccaca caaagaaagt catcggttgg aagtttggca agcagatgac
     3181 gaaagaattg gttatcgaaa cccttgacaa tgcgctctta aaccaaacac cctccgagaa
     3241 cttgatcatc cactcagatt tgggttctca gtacactagc gaagcctatg aggcaaagct
     3301 gaatgaattg aacattcggc actccttcag tcgtaagggc tgtccctacg ataatgccgg
     3361 tatcgaatcg tttcacgcct cactcaaaaa agaagaagtc tatccatcaa aagcgtatga
     3421 aaactttgaa gctgcttatt tagcgttatt tcaatacatt gaaggatttt acaatcgcaa
     3481 gcgaatccat agtagtatca actatttaac accaaatcag atggaggagt tggcattgca
     3541 agcttagttc ctagctacca cttacatttt tttggcgaga tttccacagg gtttcaactt
     3601 catcgcttcg atcagcggtc aaacggtttt ggtttgaccg ctggtcgaaa cgatgagata
     3661 ctcacccgct ggaatctcga aaaaattctc acaaatcgtg tccgaggtat tgactcaaat
     3721 ccatgtaaaa caaattaata aagagtatta agtatactaa ctgttgtaag tatacttaat
     3781 actcttttag ttattaactt tagttagtct cgttagcgta gcgtacgaaa caaaaaaaca
     3841 cgcatttctg tgcgtggacg aaatagcttt agcgataaaa aactcctttc gatatactaa
     3901 taatggctac taaccgcata tcagatcgaa aggagtttct aatgtttacc gacgataaaa
     3961 gtgtagcaca tacgagatgt catattttct ttacccaaag tatcgacgaa aagtgattta
     4021 tggaaagtta agagtaggta ttggtcagat attaagaaaa ttgtgtgaga tgaaaaatat
     4081 tgaaatcatt aaagctcatg ttatattcat ttgttagtaa gaataacgtc aaaaattagt
     4141 atttccagtt ttatgggtta ctaaaaagac gtcactgatc aatttagaaa ggtaaatata
     4201 ttctggtaat aaagatagac tgaaccccgt aaaaacctca ttgcaacgaa tcaaggaaag
     4261 acgcttttgc ttctcccttg attgggcaca ttctttgatt ttgatttttg atattgatta
     4321 tatcttttaa ttcgccatag ttatttatac aataaagaac taaattttct aagaatagac
     4381 tttctagatt ctttattttc agcttttact aaaatgaagt catcctatcc attttattca
     4441 aaacaaattt tttaataaga aagatctgtt ctttttcttt gaaggaaaag aaaaagaaaa
     4501 cgtgaaaaga aacttatgca atctatactg ctaataacct ctataagatc gttgtatatt
     4561 gatattatta tcatgtttat tttaggaaga atactatgag ttaagttttt aataagaaat
     4621 gtcgagttta tgaacctttt ttcaaagttg aaaaaatttc tttatttgat aatggcgatc
     4681 aacatctttt agaatggatg caatggttaa actgattgtt gagtatataa tcacttgttt
     4741 gtttttattt atcttttccc cactatatgg ttaatagtca gccactttag aaagagtttt
     4801 agctgttttt tacttgagga acatcatttt attggcagtc ttatttgact tattaagtga
     4861 atttatatta aaaaaattcg tttttactca taataatctc tactaagatt cctcctttat
     4921 ttgagtatca ttctcatttg attataaatt aaatccttcc ctttattatt atcaacgaga
     4981 aaaaaggtta aatgaataca aaagaaatag atcttttgtg actaataaaa agtgaacgtt
     5041 catattgaaa atattataaa tttaatttaa catataaatt gagaaaggga atctattcta
     5101 acctttctta taaaatgaac gttcgttttt aggatttctt tttgataact ttttatgtta
     5161 ggaggataaa gtatgtttta tcaaagaagc gagaagaagt ttaagtacgc aattaaaaag
     5221 aaaaaaggag gaggtggagc ggcttctttc attatcggtg caatgttttt aggaatagga
     5281 ttaatttctt gtcctacagt ttcttttgct agtgaaacaa cagagataaa tcaatcaact
     5341 gaaatccaat ctactttgaa taattctatt ctaaaagaaa gtaattcaga agaaaaacaa
     5401 aatattgatg tgtcggaaga tagtgctata aataaagatc tagaactagc ttcgaaagca
     5461 accatttctg aatcagaaaa ttcatttggt gaaactacta acaatcaaga aaatacaaat
     5521 ttatctgaag atagtattga agttcagcca gagagtatta ttcaaaagga agtcttgact
     5581 gataatgatg ctattcaaca attagaagta catcctcatg aagatagcga tgatgctgct
     5641 ttagttgaga atcagatgac aagagttaca gaagaaagta taaaaagcaa tacttcacaa
     5701 gtagataaag atacgacagt tttatctaat acaacaaggg acttagttaa tttagaagat
     5761 actgctatag aaaatgttac tccacaaaaa acgatcaaaa aagatagtat ttctttatta
     5821 gaggaaaata attcatcatc agcatcaaga actttacgta gaagtgttag gagtcttgat
     5881 gttcaaactg gagaaaactt tttagaagat tgggcactac cagacaattc taacatttct
     5941 ggaagtttga ttactcagac tggaattact tatgtgggtg taaaaactga tgatcccact
     6001 caattacatt tgaaaatggc ttacagagct gcagcaacgc ctgcttcaat tgattggatt
     6061 tatcttcgtg tggatccaga gcttacgaaa tatattgaag aaattaacat aaaaaatacc
     6121 gtaaacatcg gtgcacaagt tgggtaccaa cgatattttg aaaaagtaga tactaataca
     6181 ttgagcaatg taaatacttt tggaactccg acaggtgtaa gtgatgctta tgcacaagta
     6241 gatcaaaaaa ctggcggaat ctatcgtgtg ttattagata aatttttcat acgtattccg
     6301 ggcacgaatc ctaagagtcg aggcgcgcta tctggaaact ggggggtatt tccatctgtt
     6361 cctctcgagg ctgaaagata tgaagcgaat atctatataa aattatcgaa agatgtcgca
     6421 gagttacagc aagagcttgg aagggataag tttggtgttc aacttcgttt acaaggtcaa
     6481 tcaagttctg gtgttgcaac tattgctaaa gaaagtttaa ataagaatac tattgttgat
     6541 ctttcacaag aggagccaga tgaaaataat tcaaattggt taaactcacc atctgtccat
     6601 acaattacta ccacttatga aggaaagcaa atgggaagcg atggtcagtt cagtagtatt
     6661 ctcgaaggaa ctgataaaag tctgattaga gttcagaata cgatcatgaa taacctttta
     6721 tatggaacgg cacttgattt aggtcgacct gtttcattta atattgagat tgatccacaa
     6781 atattaaatt tagtttcaga tgatgattat attacgattt ggcaagtata cagagaaaat
     6841 agtatcaacc atcatgacgg tggatcaaat gcacctgtca tgttgaaaaa gaatatgttt
     6901 gtagataata aaataaaaat tgaagtcaac aaggataaag ctggtcagta tggaaatgga
     6961 gtttactacg ttaatgctgt tgagagcttt atgaatactt tgagttcttc atcatttgtt
     7021 ggtgcaaact ttattgatat tcctgttatg cctaaatctc taattgaaga tgaagatcaa
     7081 ttgatatcag cagaaattaa aacatggttt acagataaaa aaaatgatca agagagaata
     7141 gtaagaaact cacttgcttc aagttacatt aatttattcc ctactaccat taatttctat
     7201 gattattcaa ccaaggatac agaacaatta ttgaagttac gtgaatcaac ctacttagtt
     7261 tctacgtttg gtcaagaaat taatggaatg gatatggggg aaacatacga aattagtaat
     7321 tatgagtttg tgactgccga tcctgaaagt ttaataatca cacaaaaaga tggaaatatc
     7381 attaatttgt attataagaa actttctagt gatgctgaat tttatgaacc agaagtagaa
     7441 aaagaagaag tcaactatgg agaaacgatt gat
//
LOCUS       DAKCAA010000095         7283 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000095 DAKCAA010000000
VERSION     DAKCAA010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.098"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(170..3319)
                     /locus_tag="OUE31_002509"
     CDS             complement(170..3319)
                     /locus_tag="OUE31_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HCU0223474.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWSNLRQ
                     KIISNNQAELNDSPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIERENPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIIQIELK
                     QVTAKDGFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGVSSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEE
                     QIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHA
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3333..4550)
                     /locus_tag="OUE31_002510"
     CDS             complement(3333..4550)
                     /locus_tag="OUE31_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCU0223475.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLGDMMDVTSVKRIHQSDWTNSG
                     IRFLRARDIVSAAKNEEPSDYLYISEEKYNEYSKNSGKVSQGDLLVTGVGSIGVPLLI
                     TDDNPIYFKDGNIIWFKNEHKIDGNFFYYSFINNKIQKYIRDVAGIGTVGTYTIDSGK
                     KTPISLPTYDEQIKIGSFFKQLDHTIMLHQHELDLLKETKKGFLQKMFPKNGAKVPEV
                     RFPGFTGDWEERKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLEL
                     EEDKYANKGDLLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDK
                     EKIKESTNGTTMVHVTKGGIEQRTFQFPPDINEQQKIGAFFKQLDDTIALHQRKLDLL
                     KETKKGFLQKMFV"
     gene            complement(4540..6135)
                     /locus_tag="OUE31_002511"
     CDS             complement(4540..6135)
                     /locus_tag="OUE31_002511"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HCU0223476.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYSISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            6260..7045
                     /locus_tag="OUE31_002512"
     CDS             6260..7045
                     /locus_tag="OUE31_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SinI family restriction endonuclease"
                     /protein_id="HCU0223477.1"
                     /translation="MPNKNRTFESILNEGLTTEPASIIFDEVIDDVEDSKYHKNLKEL
                     FYFALNNGPSLFTGISVPDSDNPLIMAKIYLTKWCNKYIRDRNNPALKKPLKTFGEKD
                     AALTTRVAANANIDDQKVLNDYLRGHFLYMSAENMNGSILEEYLAEVLEPEGWIWCTG
                     SVYRAVDFCYLGTSPILLQVKNKYNTESSSSSAIRVGTTIRKWNRLNKSTKISGLDSP
                     IPNWKALIEMTEASKELAAKLTENSYLAYINEKSTRELWTLDD"
BASE COUNT         2132 a         1478 c         1198 g         2475 t
ORIGIN      
        1 tgcaacagaa ccggtaaatg aatgaaaaag atggaagaat cattattcaa tagctttctt
       61 aaatactccg ttataaaatg tgaacaagta aaaagacatc tatccctatt ttctacactt
      121 ccactttact actatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
      181 cattttcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
      241 gtgggtattt aaatggtttc gcttctggat gtttggcttt atatccttcg taatccttac
      301 tgttgataat tgctttcata ttaggaattg gatcttcacc tggcatatat tgcagattag
      361 aagcatgtaa ttctttctca gaaacaaacc actcattgga aaaggcatga atcaaattat
      421 cacttgcttg tgtaaaatag cgacgtttaa tgacaaagat atcttcatta ctatctaaag
      481 tccccacatc aaatgcattt aaaatttgtc ggtaaacttc tttgactcct tctgttttat
      541 tcaatttagc caaagctttt tcaatttctt ctcgtgcatc tgaactattc gcagcataag
      601 ttcctagtaa ttgatcaata taagtagaat caatatcata caacttcgtg gtattttcac
      661 tataaaattc gatcgttgaa aaatcttctc cctctttttc tggttcttcc tccatcaatg
      721 aacccttcac ggtctcgtac acgccaattt gttcttccaa aagttgaatt tgattgttca
      781 aagttgaaga ttgcaccatg tcatcattgt aatcatcata agtcactaac gattcatacg
      841 cacgattcaa ttcttgaaat gctttgacgt actcgatacg gatttcaagt ggcgtatgtt
      901 catcaatgga ttccatggat gaaacctctt ttaacttacc atatgcttgc ttgaatcttt
      961 ttttggattc ttggtaactt ggataaatca aacccgattc ttctttagct tctgaataca
     1021 gttttgtcgc atcctcgaca ttcttctcca ttgtcgctgg ctttcggaaa gtaacaatta
     1081 gtccttttgt tttttcagga tacgtacggt tcgtacgtga aaaggcttgg atcaatcctg
     1141 catactctag attacgatcc acaaataggg tttgaatcgt aggggcgtca aaacctgtca
     1201 atagacgatc cactacgatt actaaatcga tttgtttccc aaattgtttg aattccgctc
     1261 tttttcgtgc caaacgatta ttgatgtctc cgttataacg ctcaatgtct gctagtgacc
     1321 aggcagtatc ataatactga ttatattcct caataatttt ttgcatttct tcttgttggg
     1381 cacttgaatc tcggctattt tcttctaatg aataggtaat agcgattcgt gggaaatcag
     1441 gatcctccat cgttcgtcct tcacggatag gctgattggg aaactctttt attaaccaat
     1501 cagattcttt cgtcatctct ttgatggccc gataatactt tttggccata tcaatggaac
     1561 tcgtggttaa gatcgcagac ttcgttggac ggccatttcg aaaatcaaat tttgtatagg
     1621 cattgtctgg acggaacatt ttatgaatga ctttttggat atgttcctct gcttcaaaaa
     1681 cagtagggtc caaataactt tcttttttga cagactccat ttgatcgatc atacgattga
     1741 tctgttccgg tgaatactct gcatatgttt ctacttcttt taatttccga tagattttat
     1801 tctctaatga agtcggctcc acggtgtttt catgctctac ttgaaatcct aaaaccgagc
     1861 catcttctaa tgcattcttg atggtatagg tgtgcaagac ctctccatac tgatcatggg
     1921 tcgtacgtgc caattgccct ttggcttgtt tccgattctc agggaaaatc ggtgtacctg
     1981 taaagccaaa ccaagtggat ttcggaaaca tttttttgat ttcttccata ttttcagcac
     2041 ttaacgctcg atgacactca tcaactacaa acacgatatg ttgccccatt aatttttgga
     2101 agcgattggt tccttttttc tcttcctgtt tctttgcata tttcaacgcc gcatctagtt
     2161 tttgacgggt tgtaatgatc acaacattcg cattggcatc tgccaacaga gtttcactta
     2221 actctttggc acttcctgtt cccacgatca agctattcgc tttggcatta ccagaagaaa
     2281 ccccagtatt aaactccgaa gcaaatttcg taaactctgt ggtggtctga ttatctaaat
     2341 ctttgcggtc cactaacatg atcgttcgat cgatccccga ttttcgtgct aaaagcttag
     2401 tagatacaaa actagtcaac gtctttcctg aaccagtcgc atgccacaca taccctgatt
     2461 gatgtttatt tgcggcaata aacaaggctt gaatcgcatg cacttgataa ggatgtaaca
     2521 ccatgagggt tttattgtct tgatcttcac tgacaatcgt ataatccgca atcaagcgat
     2581 gggcatctgg gatatttagc acttgtttgc aaaactcata taagttttct acctttttat
     2641 tatctttcgt tcgccaacta aataaaaact taggatgcaa atccttcggt aaggcatttg
     2701 caaaataccg agtcgtttgt tcattggaaa ccacaaacaa ctgtaaggtc gaaaagatat
     2761 tgttccgaaa catgccttct tcagcatatt ttttgatttg attaaacgcc tgataaaaac
     2821 catcttttgc agttacttgt tttagctcga tttggataat cggtaagcca ttgatcaata
     2881 aggtgacgtc aaaacgtcga tcccgcgctt ctatgttact tccacgtttt gcaatttgat
     2941 ggaccacttc ataagtagag attcctccac caatgtcttg attggaataa aggataagtg
     3001 agacagaacc caattgcgga ttttcccgtt caatcgtgat ccgagccatc ccattttcac
     3061 cttttaacca tttcgcagca tcaaatgggg ttttcgtccg tagcaataat tcggttttga
     3121 tcgtttcaaa ctctttatcg gtcaaaggag aatcattcag ttctgcttga ttatttgaga
     3181 tgattttttg acgtaaattg ctccaaagat cttcttctga ttttagatcc ggacgatacg
     3241 tccactgatt atgtccttcc ccgaggacac gaatcaactg ttcttcgact tccgcttcct
     3301 cacggtgact aattttcatt cttcttccct ccctaaacaa acatcttttg caagaagcct
     3361 tttttcgttt ccttcagcaa atctaactta cgttgatgaa gagcgatcgt atcatctagc
     3421 tgcttgaaga aggcaccaat tttttgttgt tcatttatat ccggtggaaa ctgaaatgtc
     3481 ctttgttcta taccaccttt agtcacatgt accattgtcg ttccgttagt tgattcttta
     3541 attttctctt tatcagtcaa tagccaagta tatagatact gtttgtccaa ttccttagat
     3601 aaaaatttaa gtttccaaat atgataatgg tagattacac gttcttcatt ccacatttca
     3661 ggaccgaagc ttgttgccca taaatataag agatctcctt tattagcata cttgtcttcc
     3721 tctaattcta agtttgaata ataccatcta tcattagtat taaaattacc tactcttaaa
     3781 accctatatt ttccagaatc aagtaattct tgttgtttaa aagctctacc attcaaaaaa
     3841 actaccactt cccccaactt ccgctcttcc caatctcccg taaatcctgg aaaacgaact
     3901 tctggcactt ttgctccgtt tttagggaac attttttgta agaatccttt tttcgtttcc
     3961 ttcagcaaat ctaattcgtg ctggtgaagc atgatggtgt gatcaagttg tttgaaaaat
     4021 gaaccgatct tgatctgttc gtcataagtt ggaagtgaga taggtgtctt tttaccacta
     4081 tcaattgtat aggttccgac ggttccaatg cctgcaacgt cacggatata cttctgaatt
     4141 ttgttattta tgaacgagta gtaaaagaag tttccgtcaa ttttatgctc attcttgaac
     4201 caaatgatgt ttccatcctt aaagtaaatt gggttatcat cagtgattaa taaggggaca
     4261 cctattgatc cgacaccagt tacaagcaag tctccttgag aaactttacc tgaatttttc
     4321 gaatattcat tatatttttc ttctgaaatg taaagataat cggatggttc ctcatttttt
     4381 gcagctgaga caatatcacg agcacgtaaa aatctaatac ctgagttagt ccaatctgat
     4441 tgatgaattc gcttcacaga agtaacatcc atcatatctc ctaacttacg ctcttcccaa
     4501 tcttccgtaa aaccaggaaa ccggatttct ggtcgtgtat cattgctcat gtttgaacac
     4561 ctccagcgca ccttgtaacc acgcttcatt ttcaggtgtt gtttgcaggg aagagatagc
     4621 ttctaaaagt tctttttcta gcacttgctg ttcttgtcgt atcttcttga tgtcatttcc
     4681 gacatgaacc atatcaattg gttcttcttc ttcgaaagta tcgacatagc gtgggatatt
     4741 taagttatag tcattttctt tgatttcatc aaaggttgcc aaatgagcgt atttctcgac
     4801 atcttttctt tcagcgtagg tttcgaggat tttttgaatg ttttcttccg ataatttatt
     4861 ctgatttttc cctttaacaa attcacgact agcatcaatg aataatacat ctcgagtttg
     4921 acgattcttc ttcaatacaa tcaccgtcgt tggaatcgat gtaccaaaga acaagttcgc
     4981 aggcataccg atcacagcat aaatactgcc gtcttctaat aatttttgac gaatgacccc
     5041 ttctgcagca ccacggaata aaaccccgtg tggcaagacg atagccatag tccctgtttc
     5101 cttcaaatga tagaaaccat gaagaagaaa cgcaaaatct gctttggatt ttggcgctaa
     5161 tttcccgtag cgattaaacc gagaatcatc taagaaggtc gtatctgctg accaattagc
     5221 cgaataaggt ggattcatca ctactgcatc aaatgtgtaa ggttcatctg ttggccagtc
     5281 cttattcaac gtatccccat tgcggagatt catttcttcg gcatctaccc catgtaaaat
     5341 caagttcatt tttgctagat tgtatgtcgt tgtatttagt tcttgcccat gatatttaac
     5401 gttatctgga tgagttaagt agttacgtac atttaacatc aaggaacctg aacccatggt
     5461 tgggtcaaag acactaaaga atcgtcgttc tttttgatcc aacgtcacga tttgtgccat
     5521 catatcagaa accatatgag gcgtgtaaaa ttctccggct ttcttccctg cttctgaagc
     5581 aaattgactg atcagaaatt catacgcatc cccgatcaca tccccatcgt gacctaaaac
     5641 ttccacgtca ttcaatttct tgataacttc ggtaatcgtc acatttcgtt gttgctcatc
     5701 tgttcctagt ttttttgatt ggagatccac atcatcaaat aacccattaa attgattgta
     5761 ggtagatgcc aattgcacaa aggctttgtt tagatcgttc aattggaacg ttgcttgttt
     5821 tgcttgatcc gctaagacgt tgaaaagata ctctggtgag atcgaatacc ccaaaatatc
     5881 aacgattgtg gcaatcaggt cttcttttga ttcttcatct gaaagtaatt cacgatacaa
     5941 cattgtttgt ttgcttactg tgtcatattc ctctaaggat tcatctgcta aaagaaccac
     6001 ttgttccaac aaacggtcgg ataaatattt atagaaaatc agtcccaata aataattttt
     6061 atattctgac gcatccattt tactacggag attatctgcc gcactaaata atttttgatt
     6121 taattctgca cccaaaaaga tacactccta tctcttattt aaagttgcta tataccctct
     6181 tattttagca tactcccttt tagaaaaagc aaaaaaaaaa gaaaaaatct tattcttgat
     6241 aacaagctac gtgacgtata tgcctaacaa aaatagaact tttgaatcaa tcttaaatga
     6301 aggtttaacc acagaaccgg catccattat ttttgatgaa gttatcgatg acgttgaaga
     6361 tagtaagtat cataaaaatt taaaagaact tttttatttt gcactcaaca atggaccaag
     6421 tttgttcact ggtatatcag tacctgatag tgataatcca ttaattatgg caaaaattta
     6481 cttaacaaaa tggtgtaata aatacatcag ggataggaat aacccagcat taaaaaaacc
     6541 tcttaaaaca tttggcgaaa aagatgctgc tttaactact agagtagcag caaatgctaa
     6601 tattgatgat caaaaagtat tgaatgacta cttgcgtgga cattttttat atatgagcgc
     6661 tgagaacatg aacggaagta ttttagagga atatttagcc gaagtgttag aacctgaagg
     6721 ttggatttgg tgcaccggct ctgtatatcg agctgttgat ttctgttatt taggaacctc
     6781 accaattctt ttacaagtga aaaataaata caatacagaa agcagttcga gttcagctat
     6841 aagagtagga acaacaatta gaaaatggaa tcgtttaaat aagtcgacaa aaatttctgg
     6901 tttggatagc cctatcccca attggaaagc attaatagaa atgactgaag ctagtaagga
     6961 actggcagct aagttaactg aaaatagtta tttagcttat attaatgaaa aatccacacg
     7021 agaattatgg acactcgatg actaacaata tccttattag tatctatcca cgatacatgg
     7081 aaaaaattat aaacaaacaa aaaaactttg aatttagaaa tttctatctt acctcagatc
     7141 cttataatat cttttggatt tacgaaacaa tccccaccaa agctttaaag tataaattga
     7201 ttgtaaaaaa tccaattact aaacttaaga aaaatcaaca ctacttttta ggagacgatg
     7261 agtttgaaca attagtttaa aag
//
LOCUS       DAKCAA010000096         7250 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000096 DAKCAA010000000
VERSION     DAKCAA010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7250
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.099"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            99..746
                     /locus_tag="OUE31_002513"
     CDS             99..746
                     /locus_tag="OUE31_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCU0223478.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    875..1091
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1139..3784
                     /locus_tag="OUE31_002514"
     CDS             1139..3784
                     /locus_tag="OUE31_002514"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HCU0223479.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4094..5407
                     /locus_tag="OUE31_002515"
     CDS             4094..5407
                     /locus_tag="OUE31_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HCU0223480.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIA
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5397..6050
                     /locus_tag="OUE31_002516"
     CDS             5397..6050
                     /locus_tag="OUE31_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCU0223481.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6105..6797
                     /gene="radC"
                     /locus_tag="OUE31_002517"
     CDS             6105..6797
                     /gene="radC"
                     /locus_tag="OUE31_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCU0223482.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6947..7147
                     /locus_tag="OUE31_002518"
     CDS             6947..7147
                     /locus_tag="OUE31_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCU0223483.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         2395 a         1230 c         1593 g         2032 t
ORIGIN      
        1 atttgtctca cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt
       61 acactaaata tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac
      121 tgccaaaagc aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg
      181 actcaggtat aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg
      241 caacgatccg cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg
      301 atgtcccttt tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa
      361 tcgcattagt aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa
      421 atgaaaatct aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa
      481 ttgatggaga aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg
      541 tgacagtagc aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg
      601 tcaaaggaaa tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt
      661 atgtcaatgt tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg
      721 agaattactc agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa
      781 ctcgtcgtaa ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac
      841 ttgttgacta aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa
      901 ctggcacatt cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt
      961 gaaggtagct tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta
     1021 actcacttga gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat
     1081 acgtcctaga atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat
     1141 gacggaagaa aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta
     1201 tcagcattgg ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta
     1261 ttcaatcgta atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga
     1321 tacgaccttg caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg
     1381 gctgcctggt atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag
     1441 agagcaaggg atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga
     1501 atggaaagaa gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt
     1561 agattacagt agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt
     1621 ttttgttacc ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga
     1681 tcctcaagca cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc
     1741 cttttatcat atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac
     1801 ccgtccagaa acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta
     1861 tcaagcgctc atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat
     1921 tgcagatgaa tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca
     1981 tgatccaaac gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga
     2041 tgatgatggt acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc
     2101 tcgtaaagca atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat
     2161 gatccacagt gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac
     2221 tcaatggttt gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga
     2281 tcaagcagtg gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa
     2341 tgtccatgat tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta
     2401 tcacaaagaa acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg
     2461 ggtacaagat cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac
     2521 aatgggctgg ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt
     2581 agtaaccggt tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga
     2641 atttactggc gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca
     2701 agggcggaag atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa
     2761 gtatggagca gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt
     2821 ccgcttcagc tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc
     2881 ttcacgtttc gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg
     2941 agaaaaatca gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt
     3001 aactgagcta tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat
     3061 ctgggatgat ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga
     3121 tgctgtttca aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg
     3181 tttattgcat ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca
     3241 gggaaattct ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac
     3301 agcttctaaa gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc
     3361 agaagtgaat acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa
     3421 aatcgatcaa tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga
     3481 gttgacgata tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg
     3541 tgcagaaatc ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt
     3601 agaaaaagaa ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa
     3661 tgaacgtttt gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa
     3721 agattattta gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca
     3781 ataagaatag aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga
     3841 acatcgttac aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga
     3901 cataaatttt gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg
     3961 tggatcatgt atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt
     4021 ttctctttgt catactttta tttttcttat gtgttctatt tgttataata aaagagaaat
     4081 gggggaattg ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt
     4141 tggttcacgt cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga
     4201 gagaaaagta aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta
     4261 tttgagaagc ctattagaag aggctgggct gacagtaggt acatttactt caccttatat
     4321 cgaaacgttc aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat
     4381 ccagcttgta aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc
     4441 tggtattact gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa
     4501 agtggacgta gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc
     4561 tgtaccaatg ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga
     4621 tacaattgaa gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt
     4681 aacaggaaat attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa
     4741 tgcaccgctt tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat
     4801 gtggggagaa gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc
     4861 gcttttaggg caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta
     4921 ctgtcaattg gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc
     4981 tcgatggcca ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc
     5041 ccataatacg catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata
     5101 tcaaatcaac attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg
     5161 attgcagcaa gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat
     5221 cgaattaagt gaagtatcag atttagcaag tgagagagta tcaatcgctt cattgtggca
     5281 attcggatta gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg
     5341 ttcactttat ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga
     5401 agtataatgc agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt
     5461 acgaagccac acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt
     5521 taaaattctt aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg
     5581 aatttggcaa aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac
     5641 gtttttcgca aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag
     5701 aagaacatca gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt
     5761 tattgaagaa gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc
     5821 aacgagcaaa accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga
     5881 agaaagaaac attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg
     5941 agatcccggt agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa
     6001 cagctggggt tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct
     6061 cttttcgtat cttattttag ataagataga aaggagatgt ttttttggga aaacgattga
     6121 tcaaagaagt acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag
     6181 ctttatcgga tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg
     6241 tgatgtcgat tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg
     6301 ctactttgca tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca
     6361 aagccttgat cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg
     6421 ttcgtaccag ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag
     6481 aacatttggt ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt
     6541 tcatcggttc gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac
     6601 gttattgtgc agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat
     6661 cgcagcagga tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca
     6721 ctgtactgga ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa
     6781 tgatggaaga gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat
     6841 tgtaattttg tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca
     6901 atgttacaat ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac
     6961 agtaaaatgg ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga
     7021 cgtattcgtt cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca
     7081 agcagtgact ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa
     7141 agcttaattt tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa
     7201 gcgagtaaca aaaatacctg ccacaagaga caatttctct tgtggcaggt
//
LOCUS       DAKCAA010000097         6905 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000097 DAKCAA010000000
VERSION     DAKCAA010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.100"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..174
                     /locus_tag="OUE31_002519"
     CDS             <1..174
                     /locus_tag="OUE31_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HCU0223484.1"
                     /translation="LRNIFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVL
                     FATLLNYSIYFLN"
     gene            complement(282..1508)
                     /locus_tag="OUE31_002520"
     CDS             complement(282..1508)
                     /locus_tag="OUE31_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCU0223485.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(2262..2462)
                     /locus_tag="OUE31_002521"
     CDS             complement(2262..2462)
                     /locus_tag="OUE31_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCU0223486.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(2596..3204)
                     /locus_tag="OUE31_002522"
     CDS             complement(2596..3204)
                     /locus_tag="OUE31_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HCU0223487.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(3289..3759)
                     /locus_tag="OUE31_002523"
     CDS             complement(3289..3759)
                     /locus_tag="OUE31_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HCU0223488.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(3807..4721)
                     /locus_tag="OUE31_002524"
     CDS             complement(3807..4721)
                     /locus_tag="OUE31_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCU0223489.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            4867..5670
                     /locus_tag="OUE31_002525"
     CDS             4867..5670
                     /locus_tag="OUE31_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HCU0223490.1"
                     /translation="MTTKQLIISSFIRFKDLKETRNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKELR
                     SFLSKASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            5848..6795
                     /locus_tag="OUE31_002526"
     CDS             5848..6795
                     /locus_tag="OUE31_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HCU0223491.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         2149 a         1368 c         1046 g         2342 t
ORIGIN      
        1 ttaagaaata ttttcattgc agcaatcgat attacacttt tagttatttt cttgtcagtg
       61 cttatgtatc agttgtggct acatcatcgc ctggcaatgt ggctcatgat tccttattat
      121 ttatgggtac tattcgcaac tctattgaat tattcaattt attttttaaa ctaagcgcta
      181 aaaagagacg tcctgtaatt taacacatag aaaaagtgcc acctaagtta gattttttgt
      241 ctaatttagg tggcactctt tattaaccaa actatttttt tctagtaccc acttgttgtt
      301 ccatactcat tattctggtc ataaccataa ccattttgtt cctgtccagc gtaaggatca
      361 taactttgag tatcttgact tggtgtatag tactgacttg tatcttctgt ttgctgataa
      421 taggtattcg gatcttggta ctgatcatat gtgttttctg aataggaaga ataatcggtg
      481 tacccttcac tattcgatcc atcaccgttt gtcgaatcgc catcttccga atcatcaaag
      541 aacatcattg aagcattctc atttttcaaa ttaggtaatg tatcgcttgt ttttatattt
      601 aattgtttct tcagttcatt ttggatcgaa agaagatcat tttttcctaa aatttgatag
      661 tagatatcat tgatcatttg tccttcgcct tgcaactggt cttgtttgat tgtttcaaac
      721 gcaggggtgt agttcgtcgc tacatcaagc atgtcatccc aatctaagtc cgtcgtcaca
      781 ttgttctcaa ctgcttttaa aatttttcta taattgctta cgccatctaa acttaaaact
      841 ttattgacga ttttcgtcac tacttcccgc tgacgacgtt gtcgaccgat atcgccttct
      901 ggatcttcgt gtcgcattcg agaataggct aaaccttttt ctccattcaa tgtttgttca
      961 cctactggta catggacacc atccaaagta aagtcaattt tattattcac tttgatgcca
     1021 ccgaccgcat tgatcaaatc ttccatgcca tccaaattga tcgttacata atgatcaata
     1081 ggaatatcga gcagttgctc aattgaatcc atggccattt cgacaccacc aaatgcatag
     1141 gcatgattta atttatctac cgttccataa cctacgatat tcgtataaat atctcggtcc
     1201 aaactgatga tcgttgattt tttttgtttc ggattaactg ttactaccat catcgtatca
     1261 gaacgtcctt gttccgttct tcctaatcca ccggtatcta aacctaatag caaaaccgaa
     1321 aaaggttctt tgtcatcaat gcttactctc tcagaacgtt tggaggatat tcgattagag
     1381 tttttagaaa ttttgtttac tgtttggctc gcttctccca taaatctgat tccgtatgct
     1441 gataatccgg caatcagcaa aacaaatacc cctaacaagg ttaatagaac tttttgccat
     1501 cgcttcataa tacacctctg tttcacattt tctaaaatat tgtctcatat aactgttcaa
     1561 tcagcaaatt cactttttaa tcataagaaa actttaaaaa acatttttgt gtaacgatta
     1621 ctatttttta aaatttctca aaattcttaa ctatcatacc ataccgtgaa aaagatcgaa
     1681 agaccgaata cacgcagttc gcaatcgttt tatctttttt tacgtatttt ttccagaaaa
     1741 agcgaacaac aaggtatttt ccaaataatc gtgcagtaaa atgatcgcac atacctttcc
     1801 catcttttta acagtctttg cctaccgttc agattatcat tcgatttcac gaaaatttct
     1861 tcctatgact ggtccttttg ttaaacccat cttctattcg ttttatttcc agctcactgc
     1921 atggctctta aaatgactcg aactagtgat ttcattacca tcatctttta atggatagat
     1981 atgctcctct tcaaagtaaa acgattttct tttaaagtaa tagaattgac atggtaatga
     2041 gtatgtatac tagtggtttc acaaatggtc ttttattcaa catccaaaaa ctgaaatttc
     2101 tttaaaatcc attactaacg aagaaaatgt tccttgcttg ataattagtt aggacatgtc
     2161 aagtgaacaa atgcatttac ttagccaaaa aatctaaaaa cttcataaat agacaaaaag
     2221 acacgactct ctaagaagtc gtgtctttat tcaacaaatt attataattt agtcacttca
     2281 gcagcttgag gtccgcgtgc accttcaaca atcgtgaatt ctacttcttg accttcttct
     2341 aggctcttga agccgtctcc ttgaattgct gagaaatgaa caaatacgtc atctccgccg
     2401 tctactgtaa taaacccaaa tcctttttca ttgttgaacc atttaaccgt tccgtgttcc
     2461 ataaatgtat agcctccaaa aaagttcttg caagtaacct tgcaagaaca ttatacccaa
     2521 tttagaaaac gctagcaagc tttcgctctt ttattttcca aattattttt aagactgata
     2581 tgacggagga aatggttatt ttgctgcttc gaaacgtttg tttacttcat cccaattaat
     2641 aacattccag aatgctgcaa tataatctgg tcggacattt ttatatttca aataataagc
     2701 atgttcccaa acgtccaaac ctagaattgg tgtctttcct tccatcaatg gagaatcttg
     2761 atttgcagta gaggtaatag ctaattttcc attttccatt acaagccaag cccatccaga
     2821 accaaatcgt ccagcggctg cttttttgaa ttcttcttta aaagaagaaa aatcaccaaa
     2881 agcttcatta atcgcttctt ttatttctcc tgtaggttcg ccaccagcat ttggtgccat
     2941 gatttcccag aaaaatgaat ggttagcatg tccgccacca ttgttacgta cagctgtctt
     3001 gatatctgtt ggaatagcgt ccatatcaga taataattct tctattgttt tttcgcctaa
     3061 ttctgggtat ttctcaattg ctgcatttaa attcgtcaca taagtattgt gatgcttatc
     3121 atgatgcaga tgcatcgttt cttcgtcaat ataaggttcc aatgcgtcat atgcataagg
     3181 tagatctggt aatgtgtaag tcataaaaaa attcctcctc aatgttttct ttataatgtc
     3241 tacattacaa agagtaacaa agagaaggaa attcttcaat tgttatgcct agtcgtcttt
     3301 ttcactttga cctacttctt cttcaaaaac ctcagtttct ttaaaaataa acaacttgct
     3361 gaaaatatag ttcgctagga taacaataat ttgagtgatg attttcgcca catactcatt
     3421 gctgttcata acattgatca acaataccat tgcccccatg tccaatccgt aagaaaggat
     3481 acggtagaag aagaacttac cgcattcaat aagtgcatgt gtaaaattcg gtgattttga
     3541 atggaatacc caaagtttgt tcgttacaaa agcaaacaat acagaacaaa accacgaaat
     3601 agaattggat aaggccatac ttaaatcaaa atattggcgt gcgagagcaa aactaacaaa
     3661 atttacaatc gtagccaaac caccaaaaaa gagatagact agtatctccc aatatccttt
     3721 tgcttctaaa tatcctttta actgtcgata ctgcttcatg agccaaccta ccttattaaa
     3781 aattcttatt tatcatactc tatatttcaa taactttcat ctttatttaa aaaaattaat
     3841 tttttttgat cctttgcctt tgtctctgct tggatcgtca catgtgtaat accatatttt
     3901 aattttaata aagaaattat acgaggatat atcttttcaa tctcgcttag tagctgatct
     3961 tcaaaatcaa tatgtccgtc gaaaataatt atcttttcgc tatactgcca aatatggaca
     4021 tgatgaacat tctttacccc atcgattgct tcaatttctt gttccatttt ttcatagtca
     4081 atagcaggtg cactttgtat caaaatagcg gcagcttttt tgatcaccat tatcgcttct
     4141 atcaatatat atatcgaaat gatcagtgta ataactggat cgatccagta gatatcgaaa
     4201 aaacggatca aaattgctcc gataatcaca cttaccgaag acagtgtatc acttaacaaa
     4261 tgcaaataac tagattttat attcaaactt tcatctgctt cttgtcgtaa taataatact
     4321 gagaacaaat tcgcgagcaa tccaataact gctactgtta gcatcaaatg actatttatc
     4381 ttttctggtg aagtgaaccg cttgaatgct tcaacggtta aaaacaagga taatatgatc
     4441 aatatgaatg agttgatgaa agcactcaat atttctaaac gctggtagcc atacgtacgt
     4501 tttttatttg cttcttttcg ggccattttt tgtgccccgt aagaaaaaat aattgccaat
     4561 gtatcactaa ggttatggaa agcatctgaa acaagagaca aactccctga cataatccct
     4621 ccaataaatt ctgataaagt gatcaccgca ttcaaaacca ctactccaaa tagttttttt
     4681 gatgatctct gtggctgtgt aggcactatt ccttcctcca ttttatttat attggatagt
     4741 ctttagacaa gaataacatt tttttgatat ttcaccaatc attcagatgt ttccctaaag
     4801 cacttgtatt tcacttgata cttcgctaga attgcaagtg atgacactac tagatgagga
     4861 gtacttatga caacaaaaca attaattatc agttccttta tacgattcaa agacctaaag
     4921 gagacgagaa atgtcccatt ttggaaagcc attgtctatc ttttagtttt gagtataatt
     4981 atggctttgc caatctcttt tcaagttttt caagtcttaa acaacattca attggatggg
     5041 caaaagattg ctactcgcat tcctgatttt acaatccaaa acgggcagct tcaaaccgaa
     5101 gaaaaagaag gattcattta ccaaacaaac tccattatct tcacatttga tccagaggga
     5161 aaacgaacag aacaggacat ctctactgat ttgatgggga attttgttag tgtcgggatg
     5221 ttaaaaaaca aacttatcat agctcttcct aatacaggca cgacttctgc tttgttgaac
     5281 aataaccaat tagaacttcc ctacaccaat gaatctttaa aaaacttaac aggtaaggag
     5341 ctccgttctt ttttaagtaa agcatctata ccactttgga taaaagtcct gacatttata
     5401 ttttctattt atcctagttt tctgaatctg ctgatcactt tgctatttac caacattgct
     5461 gcttttctct atgcacgctt tcgactaaca aaagctactt ttcttgattg tttaaaaaca
     5521 ttgatctatt caatttcatt gcctactata attgcaacaa tcttgatggt ctttcttcct
     5581 tcttttgaca caagcgcctt cattgctttt gcaggaatct ttatttttgc tcaagctgtc
     5641 aaaggatggg caaaaatatc gatcaattaa gaaataaaga caactcgtta tttctacttc
     5701 aatagaccct tttagaggtt gtgacatttt tttgtcacag cccctttttt atttgaaaaa
     5761 tatttctttc tcaaaaaaca agcaaggcgc ttcaaagttc ttcttgtatg cgctacactt
     5821 agagtaaaga aaggcgggaa attaactatg tcagaaagaa tcatttatgc agatcgtcca
     5881 tttcgtgatg aatttatcga agaaatccat actatagcgc ctggttatat ctttaaaaca
     5941 gaattacaac cagaggatct acaaaatgta gagatcagtt tgggctggaa ctcagactac
     6001 caagaaaaac tattagcctc ttctaccttg aaatgggtcc aatctatctc agctggtgtt
     6061 gatcagctac cccttgagac tttttcaaag aaacatattt tactttcaaa tggtagtggc
     6121 atccacagtg aatcgattac ggagcatgtc ttaggaatca tccttgggta ttctcgtggt
     6181 ctttttcaag cacaaaaagc acagagtgac atgaaatggt taggttcatc ggtccattac
     6241 caatctatcc aaggaaaaaa aatactaatc attggaactg gccatattgg aaaaatgatt
     6301 gcaaaaaaat gcaaagcatt agacatgaac tgctatggaa tcaatacatc cggtcatcca
     6361 gcagaaggaa tggaaaagac tttttcttta aatcaactaa aggaagttct tcctgaagta
     6421 gatttcgtag tcaatatctt acctctaacg gaggaaacaa ctgggctctt tgatcagcat
     6481 atgtttgaac actttgatcc aaaatctgta ttcatcaatg ttggccgtgg tgcttctgtt
     6541 aagacacaag atctggtgca ggctttaaat aaccagcaac tttcctttgc agcattagac
     6601 gtttttgagg aagagcctct tccacaagat catcctcttt ggaaaatgga caatgtactg
     6661 attacttccc acattgcagg tttgacacct gattttcaaa agaaattaat ggctattttt
     6721 ttaaccaatc tgaaaagcta ctttgccacc catgagcttc aaaccaatca agtaaaattg
     6781 tctgcaggat attaatagct gaaaacaata ttttcaaaag aacaaagaga aggtgacaaa
     6841 actggctcta taatttatgg gactgatgaa tcagaattga ttcttcagcc ccatttttat
     6901 tttag
//
LOCUS       DAKCAA010000098         6645 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000098 DAKCAA010000000
VERSION     DAKCAA010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.101"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(47..1204)
                     /locus_tag="OUE31_002527"
     CDS             complement(47..1204)
                     /locus_tag="OUE31_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223492.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(1207..1563)
                     /locus_tag="OUE31_002528"
     CDS             complement(1207..1563)
                     /locus_tag="OUE31_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223493.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(1861..2835)
                     /gene="sgrA"
                     /locus_tag="OUE31_002529"
     CDS             complement(1861..2835)
                     /gene="sgrA"
                     /locus_tag="OUE31_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HCU0223494.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(3031..3870)
                     /locus_tag="OUE31_002530"
     CDS             complement(3031..3870)
                     /locus_tag="OUE31_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCU0223495.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            4055..4942
                     /locus_tag="OUE31_002531"
     CDS             4055..4942
                     /locus_tag="OUE31_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCU0223496.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANKGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(5536..6231)
                     /locus_tag="OUE31_002532"
     CDS             complement(5536..6231)
                     /locus_tag="OUE31_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HCU0223497.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(6215..6613)
                     /locus_tag="OUE31_002533"
     CDS             complement(6215..6613)
                     /locus_tag="OUE31_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCU0223498.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         2089 a         1313 c          974 g         2269 t
ORIGIN      
        1 aatctttttg caatgtctta attttggcat aaacaatctg cttttcttaa ttaacgaaat
       61 ccaatttttc caatatggat ctatttttct cattcctgat ttttatgatt tcagctttca
      121 gacgcgccca atcatttttt gtaggttgtc cattccagta aaatatctgt gtattcgttt
      181 gatcatatgc ctttttgtcg ataggataat cgctaatgac aatatcaggt aactgatcag
      241 cggatgcact atattttatt gggcgttcag tcatagataa tatccttttc tttgcccata
      301 attcctgtgt tttaccatac tttgattgaa tatagaatat gacaggttgt tcgtgtttta
      361 taaaaatatc cctgactaac atacagtatt gaaaaatcaa ccgtctgttc ttttcataat
      421 aagtattaag ctctggaatt ctgcgagcta ccccactaaa aaactgttgc atgattggat
      481 acatcactgg aaatatatgc tgaaaatctc tgtcttctgc tgattttcca aaagcatcca
      541 ccttcttttt tgtcccaaaa acccttgaat acaaatggat cattgccaaa ttgacatata
      601 gataattttt ttctgaagtt gtaaaacaaa tcttgaagtt tttttcaaaa ttttctacaa
      661 tagacgattc aatccagccc caactttctt gtactttatc tggagtatcc aacaaatctt
      721 cttccaaata ggtgttcatt acaccaaaca taaaataaag gtaagcttgc tctgttggag
      781 tgatgtgatt catcgaccag aagtttgctt caaaaaaagg ctctagtatg taatgcgtaa
      841 actcttcttt tgttatcaat ggatgcacaa atttgttcat ctcttctggg acatacgtaa
      901 tcgagtggcc ttgtttcatt cgttgcaacg aaattcttag taggctgatc catttctttc
      961 tatctatact acgcgtatat ggcgcatgtt tcgcaaattt ttctaatagt tgacgtttat
     1021 tttttatact tgataatata tcagaatgat tttcgtcgaa tgactgccaa tacatcaagt
     1081 gaaaaaagta tcggatacgg tattcttctc cttctatcgg attacctttt ttcaagctgc
     1141 aagataaatg atagtttttc aaaatagtat taagttctct taattttctt tgaatcgtac
     1201 gcaaacttat ataatttttt gactaagatt ttctaaggat tgataagtac ctttgtaaag
     1261 tgaatccagt aaaatataac caatcgttcc ctctaaaagt atagaataaa ctttactcag
     1321 taaaaactga gaagaaaact cgacttttat catcttgttt tctgaaagaa aagataattt
     1381 atattctgga tacctttcgc aaaacgattc tgcttgttga atcaccgaat tcatcttagc
     1441 cagggtgtag tttagatcta aagcgatatc cttcaccaca tataatttct cgtctctttc
     1501 ataacaatag ttcaaaaatt gatatacttg cctttcattg atatcaataa attcttcaaa
     1561 caaagtacat actccttttt atctattatt tagacttatt ccgacagcta catgaataac
     1621 gtacaaatag attcgttact gatttttcag agatactacc atgcgcagtg tgcattgtca
     1681 attattcttg ctcttatttt ccatttgtgt tcctgttatt tcctgtttct caaatatgtt
     1741 agtaaacaaa aatagatctg gcaaagctac aacttcgcca ggcaatacag cactctcgaa
     1801 tgaaatattc actcaaaaat ctatcgtttt attcaatttt agatctgttg cttttattct
     1861 ttatttcact cgatggaaga gagaacgaaa atagcttgct cctacaatca aaatgagtaa
     1921 cacacccatc catgtaatta gcttgttcaa ggttctacta ccagtttctg gtaaatcgct
     1981 ttttctatta tctgtttctt tcgctttttc ttgatgatca attccacgag aaacaaaatc
     2041 aggctgtttt agcacacttt ttaggttgct ccctgcattt ctcttttgtt ccttagttgg
     2101 tatgataggt accaaatcaa gttcattatt tacttttcct gtgctgcttt cgctgctcgt
     2161 gcttcctgtg ctactctcac tactcatgct tcctgtgcta ctttcactac tcgtactctc
     2221 cgtactgctt tcgctgctcg tgcttcctgt gctactttca ctactcgtac tctccgtact
     2281 gctttcgctg ctcgtgtttt ctgtgctact ttcactgctc gtactctctg tactgctttc
     2341 accgctcgtg ttttctgtac tgctttcact acttgtgcta tccgtactgc ttggcggtcc
     2401 aacaactgtc caactgcttg gtttcaaatt ctccgtgatc gtcatctgtc catcataaaa
     2461 aacaatcaaa tcaactttat ctttactctt gatctcatca atcgatagtt ctgcagaaat
     2521 cattattgta tactcaatac cagcggtcca ttgtacgtct tttaaataaa cttccccaat
     2581 aactttttct gaacttccat taccatccca accatatgtt agaacagcat gtacatcact
     2641 agcattcacg cttttgtttg gtttgactgg aatagtaatg acttgttgtg tcatgtcata
     2701 aacaatccga tcagttttca cagtaaatga aagattctca tttgcccgtt catttgcaga
     2761 agtactgatt ccaatcattg ctgcaattat actcagccca agaataacaa ataatacggt
     2821 cgctgttttc ttcatttcta tcactctcca tataattacc ttctatttga taaaggaatt
     2881 atataaaatg aaaatgatga gaacacgaca gtcagttgtg aaaatctaac aaaagatgtc
     2941 gtgtattcgc ttgaatttgt ttactttttc gtttaatcaa tgacagactt aaaaaagcaa
     3001 gaccgatatc agccttgctt tcttcatctt ttattgataa acagcagtgt atttcttcat
     3061 ccgctttgtt ttatatgcat agagtaacaa accaacaatc aagactaaca agaataatgt
     3121 agttgatata gatgcttcag ccccaaagtt tcccccagta attattgtat tttgcgattg
     3181 gatcagagtg gagaaaaaac cttgttcttg cgttccgctg actggtatac ccaaaatagc
     3241 tccttgtgtc caattccaag taatatgagc accaatagcc gtaaataaac ttcctgtact
     3301 gtagataagt gcgctgaaaa agcaacctgc taaaaagata ttgaaaactg ccagaaatgt
     3361 catgttagga ttcaatccgt gcaaaagagc aaataatgca gcagatccaa tcattgctat
     3421 taacggacca aatctaagca tctgatgctg aaaaaagcca cggaataaaa gctcttctga
     3481 tgcccccact gcaataaata aaataaaact cgttatcagc ggcacaatgt ttgcgtttcc
     3541 tgaatctaac cgatacgccc ccgtcaaata taatggacta gtaataagca gaaacactcc
     3601 aattccaaca acgagacctc ccgctaaata cccccagtct tttcctcgaa cagaaacacc
     3661 ataatcttct attctttttc cttcgacctt actagcaaga aataaagcta gtaaaaaaac
     3721 agctaaatgt ccgaccgtac cggcaattgc tccaatccat tcactatttc caataaacat
     3781 atccgcaagt gcattattga caagaattcc taaaacaaaa ccaactaaga ctattaaaac
     3841 agatccaatc aaccgaataa tcctgatcat ctttcatccc tcctttatat taagtttaac
     3901 aacccttttc tttcttgtct cgtgaaaact atgtaaatgt tctccatcat agagagaata
     3961 gatttttacg aactaagaat atctacagca accttacgaa aatgaaagac tgtctcccta
     4021 attcttctgt tagactgttt ttaataagga aaggatggga aattttttga aaaaacaact
     4081 actaattatg tgcctttcag catgtgcaat tttactattc tcaggttgta gcaagtccaa
     4141 tgaaacgatt gcaacgttta aaggtggaac acttacagtt caggattttt atgataaccc
     4201 aaaagttaaa tcaaataatc aaacactatt aaaaaaaatg attgtcttca aagcatttga
     4261 tgatgtatac ggaaaagaga tttcttcaaa ggaagtaaca aaagaatata atgaacaaat
     4321 caaaaaactc ggtccaaact acaaggaaca attaaaagca gttggccaaa cagaagagac
     4381 atataagaaa ctctttaaac agatgctggc tttccaatac ggtttgaaag ccaatgtaaa
     4441 attaacagat aaagatctag acactgcttg gaaagaattc tatccagaag ttagtacaca
     4501 gatcattcta ttttcgacta aagaagaagc agataaagca aaaaaagaag caaataaagg
     4561 agaaaatttc tccaagcttg ttcaagctta tggaaaaaat aaaacattaa aggaaactga
     4621 tggaaaaatg aattttgatt caaccaatcc agagattcct actgaagtaa aaaaagcagc
     4681 atttaaacta aaaaacgggg aagtttctga tatcattcct gtaacagatc caacgactta
     4741 tcagcaaagc tattatctag taaaaatggt aaaaaaacag gataaaggtt ctaataaaga
     4801 caaatacaaa tctgagctag aaaaaattgc taccgaagca aaaactcttg atacggaatt
     4861 catggataaa acaatccgta aagtgatgaa aaaagacaat gtaactatta aagatcctta
     4921 tgtaaaaaat atattcaaat aaacaaattt gacccaattg gggatgtggc aaaatttgag
     4981 aagtgatttt tggaaattcc ttcttatttt tgaggcaaac cacttttgcc acaacttcat
     5041 cggggccttt ttttatttgt accaaaacaa atcactggat ttgttacaat catgaggata
     5101 taatttaaaa aagtttttta tttctatcac atgaatcaat gcgccattaa gtagattctt
     5161 tcatgcttcc ctattttttc acttgccgta tcgcttcaaa aacaactatc ataaactcaa
     5221 actcgactga aaagttattt taaaaaagac taaaaatatc ccttctggac ttgttcttct
     5281 tattctgtta tactagagaa acacgaaaga tatttttatg cgacactttt catttgtttt
     5341 tatgaaattt attcaaaact ggcgtaactt cagagttaca aggatgtatt agaggttagg
     5401 gaatacatcg tttaaatgag aaataagtaa tagttagtaa tagtcaccca aactttaaat
     5461 taatgaatat tgaatcgtca gatagcctcc tcgagttttc gagaaggcta tcgtttattt
     5521 tatggagaaa ttgattcaga agtaatcagc gacctttttt agttcaccaa tcgtttctgc
     5581 ttggaaagtt tgcacccaat cttcttggaa gcccctcact gctttatcaa tcgagggcat
     5641 ctctaatact tgatctagta gctctttacc taacgttatc gcatgagctc cagatcgaat
     5701 ggctgtagtg acttgttcac aatttttgaa actagctgct aatatttttg ttggtctttg
     5761 cgtacgttcg atctcagtcc gcaacgaatc aatcactttc atagcatcaa tgccttgatt
     5821 ttgcatcctg ttataataag gtgcaatata atctgctcca ttattaatag ctaaataccc
     5881 ttgtaattct gtgtaaatag ctgtaccggt aatcaaataa ccttcttttt tcaacttttt
     5941 gatcgcttga aggcctgctt gattcaccgg caccttgata aacgtatctt ttcccagttc
     6001 ttctatgata actcgagcat cctctatcat ttcttcttcc gttcttccta ttgtctgaat
     6061 atggatagga atctgtccga ttattttttt gatttctttc atatgcgaga agaagtttga
     6121 cgctccttct tttttcagaa ttgtaggatt tgttgttacg cctgttaaat tcaaaaactg
     6181 ttgacaagaa taaatacttt ttgtatttgc tgtatcaagc atgatttcca tatagctttc
     6241 ccccattctg atcctcttga tcgattttaa tgattgtccc ctttcttaaa tgcggcattt
     6301 ccttatcttc tacatacatt gttcctggaa gttccggctc atgagatcca tcaaatttta
     6361 tcgtgatatg tcctaattca ttcaaattag tttggacaac atctcctact gctgtgatta
     6421 catacatttg tttatcaaaa cagagcttca tatcacaagt tatttctttt cttacctgat
     6481 tcaattcaat cttataacaa taatctgtta atgtttccgg tgcttcatct ccaaataaaa
     6541 tcattatttt ttctttcctg aatacttctg cttctatacc aacatctgtt acaaccgttt
     6601 caaagatcgt catctctgtt cctcctcgta aaatatcatt tgtct
//
LOCUS       DAKCAA010000099         6293 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000099 DAKCAA010000000
VERSION     DAKCAA010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.102"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..2007)
                     /locus_tag="OUE31_002534"
     CDS             complement(<1..2007)
                     /locus_tag="OUE31_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCU0223499.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDSFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
     gene            complement(2023..3019)
                     /locus_tag="OUE31_002535"
                     /pseudo
     CDS             complement(2023..3019)
                     /locus_tag="OUE31_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            3217..4458
                     /gene="sstT"
                     /locus_tag="OUE31_002536"
     CDS             3217..4458
                     /gene="sstT"
                     /locus_tag="OUE31_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HCU0223500.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            4605..5240
                     /locus_tag="OUE31_002537"
     CDS             4605..5240
                     /locus_tag="OUE31_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCU0223501.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            5431..6171
                     /gene="truA"
                     /locus_tag="OUE31_002538"
     CDS             5431..6171
                     /gene="truA"
                     /locus_tag="OUE31_002538"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCU0223502.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
BASE COUNT         1987 a         1005 c         1226 g         2075 t
ORIGIN      
        1 tttttgtgtc gcccatgttg cactgtactg gttacctgca acaagatcat attgtatcag
       61 acgataatct tctagaattt ctttttgttt ctcagttaaa tttttttctt ggataatttg
      121 actatcctct gtaacaaaga cctgttttcc attaaaacga ttagacaagc tttctgtagg
      181 atcaattgtt aatgcaggta gatgattaga tacttctgtc aacaacgcat agtaaggagt
      241 tactttgata ttcgcatgct caagagccat agcaccaaag ttattaggag caacaacttc
      301 tttatttaac gtagctgctt gttcacgact atacttgttg ttataaatga aataatctgt
      361 ctggtgctgt tctaatccat attttttcga atcattccca ctatagattg cgggtaaatg
      421 gtcaccataa aaaacaaagg taatcggttt atcgattttg tcgatttctt ggatgaattt
      481 ttttactgct gtatcggtat agtgaaggcc ttgcatataa gtttgtaatt cttttcttct
      541 attaggaatg acagcagttc cttcagcagt gtagttcaat tcactatagt aatcatcata
      601 aggcatatgg ttttgcatag tggataattg gatgaattgt gacgtttctg tattgctttg
      661 taaagctttc aaggtttctt tgtatgctga atcatccgat atgcgtgggc tttgttctat
      721 tttatccgta taagttaatt tatccggact gtctaaataa tagaagctgt caaaaccaaa
      781 tttatcaaac acttgttttc tgcgataaag agcagctgta aaaggatgga tggctatttt
      841 ttcatcgaat agatcggtaa tatttggact tattttctga cgctccacta gctgggtata
      901 aggtgtaact aacgaagcag acaggttact gatactcaag cctgtcagtc cttcccattc
      961 catgttagct gttccgccac cataaccgac ggataacatc aatcctcctg ttccttctgt
     1021 tataatgctt ttgatgtaag gaatagggtc tgtaggtact gtcagattag ggacacgtgc
     1081 aggatcactg aagctttcac ttaaattgag aacgatcgtc tgattgttta accagtcact
     1141 tcttgtttgg ttgatttcat ctgcctttgt gttgtacttt ttcattattc cattaatttt
     1201 ttctttcgaa tagccagcag gttcttccat gattttaatg tcgatattgt ttaggaattg
     1261 aatgactggt ccgttatctt ttacggcgcc ttgctggtta aagaaagtct tgtttacttt
     1321 aaataaatta aacagcaaga aagaaggcga atttttgtga ttaatgaaaa agacacccga
     1381 aaaacatcct aataatacag cgatactgat aaatcgacgt ttccaatgaa tcttcaagga
     1441 atactgtttt tgtagtctac gttgtacaat aatactagta atcaataata ggagaaggat
     1501 caatccgccc acgattaata agactgggct aaccatcgat aatagttctg acaatccggt
     1561 cagtattttt aaatctgaag gaaagacagg ctcttcccgc atttccattt tgattactgt
     1621 cgaaatagtg agcagtaagt taatgatcaa ggtagcagtc aaggcgtacc aaaaacgatt
     1681 ggaaatcaac aatagtaaga agaaaaatcc cataataatg atgattgtca ggatcatggg
     1741 tgcttgtcgc tgagtaaata tttttaaggc aacctggata gtttctttcc aaccttcttt
     1801 tggttctaaa acgaaaatct gcacgaaggt aaagcagtaa aaaaatgctg caactaaaaa
     1861 ataactttta tgaacaaaaa gccaatgaat tctttttttc caacgctgag ttaattgttc
     1921 aatcgaatca aaagcgaagt attcgatgaa acgatgaatg aaacggattt tttgtatata
     1981 aaataaaaag ataactagga gggacactgc taataaatag caaataaaaa actgcccgat
     2041 atttatcagc catgccttcc ctgagtttgg aaattcacgt ttcataaatg tagatacgcg
     2101 ataagaaact aaagggaaat tacatataac ttgagtgaca atcaaaaata cagcaagaaa
     2161 atttcctctt ccttttatac ctaatttatc agatagcatt tctaaaaata aaaacgaaga
     2221 gaaagtataa tacattgcga agagagaata tggtttagaa aacctcagcg ctgtatctgt
     2281 atttcctctg atgatgagtg aaatttgtgt catcaaaata atcaaaccga ataaaacaat
     2341 caagctgata aatacttgag gaagcttata gcggaccttt tctttccagt tccattcttt
     2401 caaaccataa cccattaaaa ataaataaaa aatccataaa atactctgtc cattctgtaa
     2461 tgcaaacggg tctttattaa atagagtaga gcagccaact aatccaattg ttaaaaataa
     2521 tagtagatat ttaattgttg ttttcgataa tttatttaaa aatccaactg tataaggaat
     2581 actacaaaaa agcaaagtac aagaaacagc ataagtaaag taattctgac tgataggtgt
     2641 taggataagc caataatcac gaatattcaa gctgccagct tgtacgtaaa aaaaagatat
     2701 tgcaaactag tgtggctatt aggaatataa aggcaaaacg acttaaataa tgtaaaactt
     2761 ttaaacgggc gattttttga tattggtaac ccatgtaaag tgggatcaaa tttgcaccaa
     2821 taacaacgga agtttgtaaa aatgtataga tgtagaatcg accagggttt gttgcatatg
     2881 taggaatagt gactgctgaa atcaatatac gctgtaaaac catcattata caagcgacaa
     2941 agattgtcag gaagccataa ctctccttct ttattttttt caagaataaa cacctcacaa
     3001 aaaaattgga caaaaacata agaaaacgtt tcctgataag ttgcccatta ataacatcct
     3061 aacttagaat atctcaaaaa acaacgtgta gacagaaaaa gtacaaaatt agcaagaaat
     3121 ggttgtttgt attgttagaa tttttagaaa attatacctt tagtttcttt gcataaaatg
     3181 atacaatgat tgttaaaatt gtgaaagggt ggtcatttgt tagagaagtt tttggatatg
     3241 tcgttagttc aacgtattgt tgttggtatt ttagtcggaa tattgtttgg tatctttttc
     3301 cccacatgga catttatttc aatattggga acgttgtttg tcagttgctt gaaggcaatc
     3361 gcacctattc tggttttttt cttgacgatg gcgtcaattg ccaagcataa aattgggaat
     3421 aagacattcg tgaagcctat tttgatctta tatttagtgg gaacattgct ttctgcactt
     3481 gtagcagtta ttgtaagttc aatttttact gttcctatta ctttacaaga aacagtatct
     3541 gaaaaagcac cgcaaagttt ggaaagtgtt ttatctacta tgttgacgaa tgtcacacaa
     3601 aatcctgttc aatctcttat tgatgcgaat taccttggcg tcttattctg ggctgtattg
     3661 ttgggactag cttttcgagc acgttcagaa tcgacaaaag agttggtgga tcagatatct
     3721 atagcgttgt cacaagtcgt acaagtgatt attgcatttg ctccgatagg gattttagga
     3781 ttggtttatc aatcaattgc tacgactgga atagctggat tggcagagta tctgcagctt
     3841 ttacttgttt tgatcggtac gatgctgttt gtcgcattag ttgtgtaccc attcctcacg
     3901 tttttgttta ttaaagaaaa tccctatcca ttgattttct tttgtttgaa agaaagcgca
     3961 cttcccgctt tctttacccg aagttctgcc gcaaatatcc cgataaacat gatgttggct
     4021 gaaagattga aattgacaaa agagtcttat tccatatcga tcccgttagg tgctacgatc
     4081 aatatgggcg gtgccgcgat taccatttcc ttgatgacgt tgactgctgt acattcttta
     4141 gggattgaag caccttttgt tttgaaagtc cttttatgta ttttgtctgc tttagctgct
     4201 tgtggagctt caggtgttgc gggcggttca ctgttattga ttccattagc atgtagtttg
     4261 tttggtatct ctaatgatgt cgcgatgcaa atcgtcggta ttggatttat tatcggtgtt
     4321 atccaggatt caatggaaac tgccttaaat tcgtcaagtg atctgttgtt tactgcaata
     4381 ggagagctag gcgcgcgtaa aagaagtggg gaaaaaatca aattgaaaga ttgtttagat
     4441 ggattaagtg aacgttgaac gttagatatt tagtattttt aaaatgattc gagtttttaa
     4501 tgagttatat agatgttcgt gtaaatagag gtttctgtta aatcaagata aagtcgctta
     4561 taataacaat taaaagcata ggtaattgtt attggaggcg tatcatggat tttttacgta
     4621 aatttggttt tttcttttta ttattaggcg tgctgagtga ttttttgact ccgtacgtat
     4681 taggattgta ttatcctgaa ttagatcaaa tgaagagcgt gatcagtgta tttggagagg
     4741 tttccagtcc tgtaagaaaa gcgtttctta tttggtctgt ggtttcaggg atctttttca
     4801 tcctgtcatt gcctgcattg tatgctgcat ttgtaagtac atctcgtgtg ttagctaccc
     4861 tagttacagc agccatcgcg ttctatggta taggtgattg tatctttaca ggtttgttca
     4921 gtatcaatac ccatgaatct tcgtggaatg tctcgacatg ggtccataat atcggatcag
     4981 gtttaggtta cagtggtttt ttattgtttc cagttcttct tttcttgatc tatcgaaaaa
     5041 atgggcaaat ggacgtaagc cacttatacc ttggactgtc tgtgatcagt ttgctttttg
     5101 cggcgattta tggactggca agaattcctt ctataaattc ttggccatta ctgaataaaa
     5161 taggtttttg ccaaagaatc agttttttct ttaattatgt gcccattgcc tggttgagta
     5221 tcttgcatct caaacagtaa aacttgagcc gtcaaattga acagtcagcg gatacttcat
     5281 ccggtggctg ttttttgttt ttctgaaata tatatttcca cagttttctt gtatagcttc
     5341 tgttttagag aagaaaggag ctatattttg tgctacaatc ttaaaaaggt agagagaaga
     5401 ccaaatggaa gacagaggag ccactaaaat atgagaaaca tcaagttgac aatcgaatat
     5461 gacggaaaaa gatattcagg atggcaaaga cttggagatg acgataaaac cattcaagga
     5521 aaaatcgaaa aagtattgca tcagatgaca aatgaagaga tagaaattat tggatcagga
     5581 agaacagatg ctggcaccca tgcgcgagga caagtagcaa attttaaaac aaacacagaa
     5641 attggactgg cagaaatgat cgactttatg aatcgttacc ttccgcggga tattgtcatc
     5701 aaaagaatcg aagaaatgcc tgagcgcttc cattcaagat ataatgcggt gggcaaaaaa
     5761 tacagctatt atgtttggaa caacgtgatt ccttcagcat ttgagcgaaa ccacagcttt
     5821 tatttccctc aagagttgga tatggacaag ctgaatgcag cttgcgaaaa attagtgggt
     5881 acacatgatt tcattggttt ttctgcattg aaaaaatcaa aaaaatccac agtgcgtacg
     5941 attgatgaat tatctatcga acgaaaggga gaaatgcttc attttacttt tgtcggagac
     6001 ggattcttat ataaaatggt gcggattatc atggggacat tactagaaat cggcacaggt
     6061 gccatgccga tagaaacaat cgatgaaata tttgaaagca aagtgcggca acatgcagga
     6121 gaaaccgtcc ctgcacaagg tctgtttttg gatgaagttt attatcgata aaaatacttt
     6181 gataatggat gaaacgcatg tttcacagta taaatatcga tgttaaataa tgtatgaagc
     6241 aaattaaaga aatataaaaa aagacttttt agcctgttta tgtgtacagc taa
//
LOCUS       DAKCAA010000100         6218 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000100 DAKCAA010000000
VERSION     DAKCAA010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.103"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(658..1035)
                     /locus_tag="OUE31_002539"
     CDS             complement(658..1035)
                     /locus_tag="OUE31_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HCU0223503.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(1081..1269)
                     /locus_tag="OUE31_002540"
     CDS             complement(1081..1269)
                     /locus_tag="OUE31_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HCU0223504.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            1440..1982
                     /locus_tag="OUE31_002541"
     CDS             1440..1982
                     /locus_tag="OUE31_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0223505.1"
                     /translation="MKFGGHFLNKKQDQEYYIEKLEKENLELKERIRYYETKFCKRGD
                     CMKPNPVETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERGFSLPNKERLIKIA
                     ELSNKTIDWIKWGTLEEYITSYLIGIGYELYIKDFPEIPHKVFKDIQEKYSDTFSLDK
                     DYELLDSIIKNIFTKYYSNG"
     gene            2177..3073
                     /locus_tag="OUE31_002542"
     CDS             2177..3073
                     /locus_tag="OUE31_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0223506.1"
                     /translation="MEINLFEAGNRIKQIREKHGYTMADLGKLVDANSPSTINNWEKG
                     NNLPNRKRLEKIALLGGTSVEWIKYGDFSDYVYRLTQNIEEKILKEYGETTLNNYREA
                     LLDELTIEKITYEEDTKILAAAEKINTQNIFQEVKYMYSPDEDYRNIEVKPDLGLTDD
                     NKNIKMIGQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAE
                     IGGVSELYLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKID
                     DPDKREISLNAICQLSLLDKMG"
     gene            3122..4504
                     /locus_tag="OUE31_002543"
     CDS             3122..4504
                     /locus_tag="OUE31_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223507.1"
                     /translation="MKPNLSLTSERIRKIIESKGLTLERFGDLIGDTPISSVNNWLRG
                     VSLPNKNRLLTIANIGNTSVDWIKWGTLEEYIASYLIDSGYELYIKDFPEIPYKVFKD
                     IQEKYSDTFSLDKDYELLNPIIKFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTT
                     LTNYYRGERNPRNTETWNILADYFHVPVSYLMGLDETNVELKNLNIGNNIKNIRKSKN
                     MTQTDFAELMGLSRSYIGDLENNRSNPSIKTLEAIARALDVPIVALINDSSTDNIVEP
                     YESLTAENILLKQENEELKYEVESLRKRLYEIQQVVNQGAEKMIPNLKDVSKRIKYIR
                     KKLGMTMEQFGSHLSNSPKSTIATWESGRNIPSQKKLQLIAIVGETTTDWIKWGTLEE
                     YITSYLIGIGYELYIKDFPEIPHKVFKDIQEKYSDTFSLDKDYELLDSIIKNIFTKYY
                     SKEFEVTQIP"
     gene            4518..5300
                     /locus_tag="OUE31_002544"
     CDS             4518..5300
                     /locus_tag="OUE31_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223508.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDPKKVGRKIRSIRK
                     KLGLTMQEFGYEVSNSPRSTVSTWEHGGNLPNKAKLKKIADIANCSVEDLLFDEGFIS
                     EKSQVKLINELKEENSKLKEKIKYYECLFDGIESLLNSRKNS"
     gene            5340..5951
                     /locus_tag="OUE31_002545"
     CDS             5340..5951
                     /locus_tag="OUE31_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCU0223509.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
     gene            6087..>6218
                     /locus_tag="OUE31_002546"
     CDS             6087..>6218
                     /locus_tag="OUE31_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCU0223510.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     "
BASE COUNT         2376 a          869 c         1146 g         1827 t
ORIGIN      
        1 aaccagataa aaattatggg gaatgggctt attatcagtt gaaagaacaa ataataaata
       61 aagggaaaag atatggaata gaagttaaaa gtgagtagaa taagaaatcg ttgatttggc
      121 aacgaaatag tgaggggaca ctcactcact gaagggttag ctctgtcaag ttgtgtaacc
      181 agacggaagg acgaatattg ttgaggtttt agaaccatgt aaaacaacac agttctcaaa
      241 tgttacggat aaaccgtttg cgggaaatca ggttttaaaa ccatgtaaaa caacacagtt
      301 ctcaaataag gctttattga attgatcagt agtttctgtt ttagagttat ataaaacgac
      361 atggctctta aataggagct aacgaagaaa aagaaggtac tccgttttgg agttaagtag
      421 aaataaaaaa atagaatcgt tgatttggca acgagttgaa aaatacgcaa aactatggtc
      481 accaagggat aaccctgaaa ctgatgatcg ctatatctta ctagtagtta aacagtctaa
      541 atagtactca tttattgtat tgattctaag ggaacctgca ataaatgagt actattttac
      601 ttttaattcc gctatctatg tcattaggca actaaattgt tattaatata tttacgttta
      661 ctcgtatatt tttagtaacg catctgtcaa aactttagaa aaatttattt tatctttttc
      721 ccctctagct actaaccatt ctgggactgt gacgtttttg cgtacggtct ttttttggat
      781 aaatggagaa ggatcacttt gaataagaga aacaattttg ttattgccca aattatttag
      841 ttgatgaata tctgttggag aaggaactga aatatcttca tcaatatagt aagctagaat
      901 cccatcaaga aattctttag cattggacat agcttcttca aaattatctc cttgtgttgc
      961 tccagcaaaa tcaggaaaaa ctactgagta gccattttct tcagcagaaa aaattacagg
     1021 gtaacttttt ttcatttcca ccactccttt cgagttaatc caatgaacta aaggactggg
     1081 ctatttcagc cctaagtcct ttagtaactt ctgctctgtc ccttttttta aatcctgatt
     1141 actatgaaca ggaataggaa cgggtgggaa tccttctttg gctacaatat gatggctgcc
     1201 agttatcctc accactttcc aaccattttt cttggctagt ttgagcattt ttttaccggt
     1261 aagtggcatt cgcgactacc tccttacaaa tattattata cgcattatgc gtataaaggt
     1321 caagagtttt tacattaaaa gtagaatgta agtgtcacaa tagggtatac cctattgtat
     1381 catatggtaa agtacagtat aataaggttt ggaggtgtaa cactagggtg taacacaatg
     1441 tgaaatttgg aggtcatttt ttgaacaaga aacaggatca agaatattat atagaaaaat
     1501 tggagaaaga gaacttagaa ctcaaagagc gaataagata ctatgaaacc aaattctgta
     1561 aaagaggtga ttgtatgaaa ccaaatcctg ttgaaacagg taaaagaatt aaatcaattc
     1621 gttctaattt tggaatgact atggaacaat ttgcagattt aattggaaat gctcaaaaag
     1681 gaaatattaa taattgggaa cgaggattct cccttcccaa caaagaaaga ttaattaaaa
     1741 ttgctgaatt aagtaacaaa actatcgact ggattaaatg gggaacttta gaagaatata
     1801 taacttcata ccttatcggt ataggatatg agctatatat taaagacttt ccagagatac
     1861 ctcacaaagt ctttaaagac attcaagaaa aatatagtga tacgttttcg ttagataaag
     1921 actatgaatt attggattct ataataaaaa atatatttac aaaatattac tcaaacggtt
     1981 gaattgatag atggactcaa agaagaaaat tcaaagttaa aagagaagat aaaatactat
     2041 gaatgtttat ttgatggtat agagagtctg ctgaactcac gaaaaaatcc ctagttttta
     2101 tgaatgaccg ttttgtaaat ctgattgaaa tagatttata tgatttcggt atatgatata
     2161 cattaggagg tgtcgaatgg aaataaatct ttttgaggct ggtaatcgaa taaagcaaat
     2221 acgagaaaaa catggatata ctatggcaga cttaggtaaa ctggttgatg ccaatagtcc
     2281 tagcacaatt aacaattggg aaaagggaaa taacttacct aatagaaagc gtcttgaaaa
     2341 aattgcacta ttaggtggta cttctgttga atggataaag tatggagatt tttccgatta
     2401 tgtttatcgc ttgacacaaa atatagagga aaaaattctt aaagagtacg gagagactac
     2461 actgaacaac taccgtgaag ctcttctaga tgaacttacg attgaaaaaa tcacatacga
     2521 agaagataca aagatattag cagctgccga aaaaatcaat acacaaaata tttttcagga
     2581 ggtgaagtac atgtattctc ctgatgaaga ttatcgaaat atagaagtca aaccagattt
     2641 aggactgact gatgacaaca aaaatattaa aatgattgga caacgtataa ggaaaataag
     2701 aaaaaaagag aatattacat tagaagaatt cggcaaacta ttctctccta cagctgataa
     2761 agctgttata agcaactggg aaaatggtaa aaaccttcct aactcagaaa gaattaaaaa
     2821 gattgcagaa attggcggag tttctgaact ttatcttatg acgggtgtcg attcaagcgt
     2881 agcagaatca atgtattttc tatctgaagt agcattggat gctttggaac gtctgtcaat
     2941 tgaggaagtc aatagaataa ttgaaagctt cgccggttat cttaatgtga tttcaaaaat
     3001 tgatgatcca gataagcgag aaatatctct caatgctatt tgtcaactat cacttctcga
     3061 taaaatgggt tgattcacaa aaaatattga aagattactt tactcacgag gaggcttagc
     3121 tatgaaacct aatctatcgt taactagtga acgtattaga aaaattatcg aatccaaagg
     3181 tctgacatta gaacgattcg gtgatttaat tggcgacaca ccaataagtt ctgttaataa
     3241 ttggcttaga ggcgtgtctt tacccaataa aaataggctt ttaacaattg caaatattgg
     3301 aaacactagt gtagactgga ttaaatgggg aactttggaa gaatacatag cttcatacct
     3361 tatagattca ggttatgagc tatatattaa agactttcca gagatacctt acaaagtctt
     3421 taaagacatt caagaaaaat atagtgatac gttttcacta gataaagact atgagttatt
     3481 gaatcctata ataaaattta ctataggggg cgttactttg aatagaataa aattttatat
     3541 tgattccagt aaaaagacca ttaaacaaat tagtacagaa actggtatta actatacaac
     3601 tcttacgaac tattaccgtg gtgagcgaaa tcctagaaat actgaaacat ggaatatcct
     3661 tgctgattat ttccatgttc ctgtaagtta tttgatggga ttagacgaaa caaatgttga
     3721 actcaaaaac cttaatattg gaaacaacat caaaaatatt agaaaaagta aaaatatgac
     3781 acaaactgat tttgctgagt taatgggtct atcacgatca tatatagggg atttagaaaa
     3841 caacaggagt aatcccagta taaaaacact ggaagctatt gcaagagcat tggacgttcc
     3901 gatagtagca ttaatcaacg attcttctac tgataatata gtagagccgt atgaaagttt
     3961 gacagccgaa aatatccttc ttaaacaaga aaatgaggaa ttaaaatatg aggtagaaag
     4021 cttacgaaaa agattgtatg aaatccaaca agtagtaaat caaggagctg aaaaaatgat
     4081 tcccaatcta aaagacgtaa gtaaaagaat caaatatatc agaaaaaaat taggtatgac
     4141 tatggagcaa tttggttctc atttaagcaa ctcacctaaa agtacaattg ctacttggga
     4201 aagtggtaga aatatacctt ctcagaaaaa gttacagctg attgctatag taggagaaac
     4261 caccactgac tggattaaat ggggaacttt agaagagtat ataacttcat accttatcgg
     4321 tataggatat gagctatata ttaaagactt tccagagata cctcacaaag tctttaaaga
     4381 cattcaagaa aaatatagtg atacgttttc gttagataaa gactatgaat tattggattc
     4441 tataataaaa aatatattta caaaatatta ctcaaaagaa tttgaagtaa cccaaattcc
     4501 ataagagagg tgattgtatg aagccaaatc cttcagaagc aggaaaacga atcaaacaat
     4561 tacgcctttc atgtggtttt actatggaag aacttggaag gaaaatagat aattcaccac
     4621 gtgcgaccat atccaactgg gaacgtggga ccaatttacc aaatccacaa aagctgaaat
     4681 tattatcaac tatcactaat tcaacaattg actggattaa atggggaact ttagaagaat
     4741 atataacttc ataccttatc gatatagggt atgagctata tattaaggac tttccagaaa
     4801 tacctcacaa agtctttaaa gacattcaag aaagatatag taatacgttt tcgctaaata
     4861 aagactatga gttattgaat cctataataa aaaatatatt tacaaaatat tactcaaaag
     4921 attttgaaga ttatcgagac atagaagtta aaccagaccc taaaaaggta gggagaaaaa
     4981 ttcgttctat tagaaaaaaa ttaggactta ctatgcagga atttgggtac gaggtttcta
     5041 attctcctag aagcactgtg tcaacatggg aacatggtgg taacttaccg aacaaagcca
     5101 aactaaaaaa aattgcagac attgcgaatt gtagtgtaga agatttgctt tttgatgaag
     5161 gctttatttc tgaaaaatcc caagttaaat tgataaatga actcaaagaa gaaaattcaa
     5221 agctaaaaga aaaaataaaa tactatgaat gtttatttga tggtatagag agtctgctga
     5281 actcacgaaa aaattcctag ttaattaaac tagagtaaaa ttatttgtag gtgttaaata
     5341 tgttagttgg ctatgcacga gtcagttcag atgatcaaaa tttggaaaga cagcttgaag
     5401 aatttagaaa aattggtgtc gaaaaagtat ttgctgagaa aaaatctgga cgtaacacag
     5461 tagaacggcc agagttcaat aaaatgttgt catttgtcag agaaggggat acgcttgttt
     5521 ttgagtcgct tgaacgctta ggaagaaatt ctgatgaaat actagaaaca gtatctttta
     5581 tagataaaaa tggtatgggc ttaatggttt tgaatttacc aattttagat acaaaatttg
     5641 gtgatccaaa cttagaaaaa cttgttagaa gcttagtaat taacattttt tcttggacgg
     5701 ctcaaaatga gagggaggaa attaagagaa aacaaaaaca aggaatagca attgcgaaga
     5761 agaaaggagt ctataaagga aaaccctacg aatattcttc tactgcaaag aatccacaaa
     5821 agaggtttat ctataatgaa atagtaagaa tgcttggaga aggtgttccg attaagcgaa
     5881 ttgcagaaaa aacaggaaca aatagaaatt tagtctatag aataaagaaa agaataagtg
     5941 aatctgattg attttaagtt ctttgagaaa tcaatgttac gagagaagga ttctaagcct
     6001 gtttcaaact ttggttctgt tgcaaagttt taaatctact atcaaataag gtagaataat
     6061 agaaaaagat agcaggagga atgacgatga atcattttaa aggaaagcaa tttcagcagg
     6121 atgtgattat tgtagccgtg ggctactatc ttcgttataa ccttagctat cgtgaagttc
     6181 aagaaatctt atatgatcgt ggcattaacg tttctcat
//
LOCUS       DAKCAA010000101         6173 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000101 DAKCAA010000000
VERSION     DAKCAA010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.104"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            725..811
                     /locus_tag="OUE31_002547"
     CDS             725..811
                     /locus_tag="OUE31_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCU0223511.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="OUE31_002548"
     CDS             complement(932..1621)
                     /locus_tag="OUE31_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223512.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="OUE31_002549"
     CDS             complement(1628..1906)
                     /locus_tag="OUE31_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223513.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="OUE31_002550"
     CDS             complement(1866..2780)
                     /locus_tag="OUE31_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCU0223514.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="OUE31_002551"
     CDS             complement(2762..3142)
                     /locus_tag="OUE31_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HCU0223515.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="OUE31_002552"
     CDS             complement(3592..3879)
                     /locus_tag="OUE31_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCU0223516.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="OUE31_002553"
     CDS             complement(3899..4123)
                     /locus_tag="OUE31_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HCU0223517.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="OUE31_002554"
     CDS             complement(4578..4748)
                     /locus_tag="OUE31_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223518.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="OUE31_002555"
     CDS             complement(4763..5296)
                     /locus_tag="OUE31_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCU0223519.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="OUE31_002556"
     CDS             complement(5317..6159)
                     /locus_tag="OUE31_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCU0223520.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAKCAA010000102         6078 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000102 DAKCAA010000000
VERSION     DAKCAA010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6078
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.105"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            5..1189
                     /gene="iadA"
                     /locus_tag="OUE31_002557"
     CDS             5..1189
                     /gene="iadA"
                     /locus_tag="OUE31_002557"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HCU0223521.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            1300..1503
                     /locus_tag="OUE31_002558"
     CDS             1300..1503
                     /locus_tag="OUE31_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCU0223522.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(1604..2266)
                     /locus_tag="OUE31_002559"
     CDS             complement(1604..2266)
                     /locus_tag="OUE31_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCU0223523.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(2279..3781)
                     /locus_tag="OUE31_002560"
     CDS             complement(2279..3781)
                     /locus_tag="OUE31_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCU0223524.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            4329..6008
                     /locus_tag="OUE31_002561"
     CDS             4329..6008
                     /locus_tag="OUE31_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCU0223525.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
BASE COUNT         1919 a         1096 c         1294 g         1769 t
ORIGIN      
        1 atgtatgaaa atcattcgac aaattgaagt gtttgcacca gattacttag gaaaaatgga
       61 tgtactgatt gccggtggga agattttggc tgtagaagaa cagctagaag gcggctacga
      121 aggagtggaa gtagaagaac tttcaggtga gggaaaagta ctaaccccgg gtttcattga
      181 ctgtcatttc catattttag gtggaggagg agaaggcggt tatcaaaatc gaacgccaga
      241 agtcacattg agccaattga ctacagctgg tgtaacgaca gttgtcggtt gtttgggaac
      301 agacggagaa ggtagagata tgactgcgtt gatcagcaaa gcgaaaggtc tggaagcaga
      361 aggaatctcc acttatgtat acgaaggttc gtaccgattg ccggtaaaaa cagtaacaga
      421 ttctatcatc aaagactttt tgacaattga taaaattatc ggaatcggag aaatcgcagt
      481 atccgatcac cgttcttctc agccaagttt tgaagagttc gctcgtgcag tagcagatgc
      541 tcgtgtagga ggcatgttat ccggaaaagc tgggatcatc aatgtccact taggcggagg
      601 aaaaagaaag ctagagctat tgacacgaat cgtagaagaa acagaaattc cgatcacaca
      661 atttttgcct actcatgcaa atcgcacacc agaattattt gaagcttgcg tggcatttgc
      721 caaacgtggt ggcacgattg acttcactgc tagcgaagat cctgattttt gggagaagac
      781 agatggtgaa gttcgcttca gcaaagcact gaaacgattg atcgaggaag atgtttcttt
      841 agataatttc acgatgacct cagatggaca aggaagcttg ccttattttg atgaaaacaa
      901 tcatttccta gggttaggag taggaagtgc caaggcattg ctagtaggga tcaaagaagc
      961 tgtgcaaaaa gaaagtatcc ctttggaaat cgccttacga gctataacca gtaatccagc
     1021 acgtatattg aaattggata aaaaaggaaa aatcgaaatt ggtgctgatg cagatctgtg
     1081 tatcttggat aaagaaacgc ttgatattga tacagttatc gctaaaggag aaataatggt
     1141 ccaagaaaaa gaagtcaaag tatgggggac tttcgaaaaa agtttttaat caacagctct
     1201 aactatcttt tttagaaaac gagcgttctg tttgtctgta tctgttgttg atgttaccct
     1261 gaaggtagat caataaacaa actaagagga ggaagcacaa tggcagattt aaaaggacgt
     1321 tctaaagata tgaaagataa agtagtcggt gaaggaaaag aagcatacgg caaagcaaca
     1381 gacgacaaga gcaaagaaac agaagggaaa gcacaatcac taggtgctga catcaaagaa
     1441 aaagctcgaa atttaggcga cgaagtcaaa gacaagtttt ctcgaaaaga cgaaaaaaaa
     1501 taaaaaccac ttattactaa ttgaatcaag caaataaaaa atccgaacca tatctgcgag
     1561 acagatatgg ttcggatttt ttatttgatc attatcctgt tttttaaact tcgatttttt
     1621 gaaatttttt attttttagt tcaaagactt catcacagct ttttgctact tcaatctcat
     1681 gagtcacgat gataatacag cgattttgtt catgggcgat ttcttggaaa agtttgacga
     1741 tatcttgtga agttgtttca tctagatttc cagtaggctc atccgctacg attagttgat
     1801 gttcacagca gatagcacga acgatagcga ctcgctgctg ctgacctccc gaaagtttgg
     1861 tcacctgttt ttttgctaat atttcatcaa ttcctacacg agccagtcga tctaaagcaa
     1921 cttgtcgata attctcttgc ttggtcttag tgatttccat tgctgctatg acgttgtcta
     1981 gagccgataa ataaggaagc aagttgtaag cttggaaaat aatcgagaca tcatttttac
     2041 gataacttct taacccgatt ttgttcagtg aacgatcttg atagtatacc tttccttctt
     2101 ttggtgcatc tagtccagaa ataagcgaaa gaaaagtcgt ttttccagaa ccacttgctc
     2161 ctaaaatagc gtacattttt ccagcttcga aattcagttc tacatcttta taaagcgcat
     2221 cttgcggatc ttgataccaa aatcccaatt gttctgtccg taacatcaaa ttcctccttt
     2281 agtttaatag gatttttctt gggtttaatc ttaatatccc tatagaagct aaaaagacag
     2341 aaaacagact gattccaaat gctactccgg ctaatagtcc caattgtgca ggtttgacat
     2401 tgatttccaa ttcgctgact tgatcagaaa cagcaaatgg attattcgtg gttccttgtt
     2461 gaccatcgcg ttgaccgcct tgttcttgtc tgttacctgg catttgtcca ccgccaggag
     2521 cttgctggtt ttgtgtcgtg gtttctgtct gttggtcaag tagctgctgt cccacggcat
     2581 tcgcgacgac gtttccgcta agcgaagcaa ctcctaatgc aagaatcata caaatagcca
     2641 cttcggtaaa caattggaga atgattttac ttctggattc tcctaaagat agcaagacgc
     2701 ctaactcatg ccgacgctcc cgaatggtaa tcataatgat cagagtaagt atgataatac
     2761 cggctacagc cactagtaaa acaacatttt tagaaaaact tgccacgttg tttaaaggtt
     2821 ccaacattga ctgatacatg gaatcatttg attgtaagct aaatgtatct gtgtcgatca
     2881 gcttctcagc ttctttgaga aactcatcca ttttatctgg atcagataga gtgtaaatag
     2941 cagaatctat cgtgttatcg tcagatgtcc catttagttc atttgcaaaa gtgtaagaag
     3001 tgtaaagtgt attcgacgga ttcatgaagt tgaatttcat acccatactg ccgcttgttt
     3061 cgctggattc ataaattcct ttgatcgtca tttcataagt ggtatcttca tcttcagtac
     3121 tcgtgattgt gaaagtatct ccgactgcca ggtcatttgt ttctgctaga gtagaatcaa
     3181 tgactacatt gtttgtgcct ttgtcgctgt catctattcc ttcaccatcc gtgatttttg
     3241 ctgttccatc agaaaaatta ctattttgtg cagttgctga cacaccactg atttgaaagt
     3301 ctgcttgagt catttgcgga ttcccgccca ttcctccagc aggttcaccg cctgcatcag
     3361 tagtttctga actgtcttca cttgaatcag aactagtgat ggcagttatt ccatcttttg
     3421 ccatagctga ggcggaactt tcaaaggaat aactctttac attatctaat tcagctattt
     3481 tttccgcgtc cgttaaggaa actggtgtaa gagaaaaact gcctggatct ggacgttctt
     3541 cagtggtaga accgcttgaa gaagtttgtt cctgtttttt aaatgaagct tctcgattgg
     3601 cacttaaagt cactgttgct ccaacttctt tttgtgcttg attcgctgct tcttctgcag
     3661 cgcttcgaat cgtgaggcca gctagcacaa aaataagaat ggctgtgaac acggcaaaca
     3721 ataacaatga acgtccccat tttacttttg tacttttcca tgcacgtttc ataaaattca
     3781 tattttgcat ccctcctagt agatgcattt gataatagac aacctatctt aaagctagct
     3841 taaatcttat gctgtttgca caccatcaac atgaggttct gtatatataa aaagtcacta
     3901 tagttattgc aaaaaatgtg gtaaaatgaa aaaagtatgt ttcaaaccga cgaagaagaa
     3961 atgaaagagg aatagcaaaa gaaatcctag atgctacaga gggattttta cgtgcatagt
     4021 tgttctaaca attgctgata ctagcgattt agtttatttg ttgtataata atggggaaca
     4081 gctgaatact tatataagta ttctggctat agcgtttcgc aaaagatcca ttttgttaat
     4141 gaagtatatc caaaataaaa tgcccatcca actgtcagaa cgcggatgtg ctggtaattt
     4201 tcctgctgat tctccataag ttgagaaata gtgattttgc atatgcttca ttggaatggc
     4261 tcatatattt agataaagaa gaaaatcgac atctttaaac ttggatgtca taagaagagg
     4321 tgaagtttgt gagtaccatt aaaattatcc cattaggcgg cgttcgtgaa aatggaaaaa
     4381 acatgtatgt cgcagaagtg ggcgaggata tttttatttt agattgtggg ctaaaatatc
     4441 ctgaaaatga gttgttgggg atcgacgtcg taatccctga ttttacgtat ttagaagaaa
     4501 acattgatcg tgtagctggt gtctttttaa cacatggaca tgcagatgcg atcggggcac
     4561 ttccttactt gttgtcaaaa atttctgtac cagtattcgg gacagagttg acgatcgagt
     4621 tagcaaaatt gaatgtcagt cgtaatgaag cagccaaagg atttaaggat ttccatgtgg
     4681 tagatgagca tacagaaata gactttggtg aaacagtagt gagctttttc cgtaccactc
     4741 atacgatacc agattcagtg gggatcaatc tgaaaacaaa agaaggtagt atcgtttata
     4801 cgggagattt taaatttgac caaacggcta tcccaatgta tcaaacagat tatgcacgat
     4861 tggcggaaat cggcaaagaa ggagtcttag ccttactaag tgaatcggca aatgcagaaa
     4921 atcctcagcc tgtagcttct gaagcccaaa tagcagatga agtatttgat acgatcaaat
     4981 attgggaagg gcgtatcatc gtcgcttgtg tagcaagtaa tttgcaacga gtgcaacaag
     5041 tattggatgc agcagaaaaa gcacaacgaa aagttgtctt gactggtcaa gatttcgaac
     5101 gaattattcg cacagcgatg cgtttagaaa aacttcaatt accaagtgaa gatctgcttg
     5161 ttacgttgaa agacatgaaa aactatgatc cagaagaact gatcatttta gaaactggcc
     5221 gaatgggtga acccatcaag tctctgcaaa aaatggcaaa cggtacacac cgtaatgtca
     5281 agattgaaga aggagatttg gtttatatca ctactacgcc aagcatcgcg atggaaacca
     5341 tcgtggcgaa aacggaagat atcatttatc gagctggtgg aacagtgaag ttgatctctg
     5401 agaatatgcg cgtttctggc catgccaatc ctaatgactt gcaattaatg atcaatttga
     5461 tgaaaccaac atattttgtg ccagttcaag gagagtatcg tgaattagct gctcatgcag
     5521 atttggctca tgcagtaggg atgccataca aaaatatcta tattactgga cgcggagacg
     5581 tgctggaata taagaacaag cgtatgagtg ttgcaggaac tacaagtgca gaaaatgtaa
     5641 tgattgatgg attaggcata ggtgatatcg gaaacattgt tttacgtgat cgaaaaatct
     5701 tgtcagaaga cgggattttc gtagcggttg tcactatcag tcggcgagaa aagaaaatca
     5761 tttcaaaacc tcaaattact tcacggggat tcgtttacgt aaaagctagc cgtgatctga
     5821 tgaaagaaag cagcaatatg attgaaacaa tcgttgagaa acatttagaa agcaatgatt
     5881 ttgagtggag caaattaaag caagacatcc gagatcaatt aggccgttac ttatttgaac
     5941 aaacaaaacg ccgcccagtg atcttgccag tcattatgga agctactcaa cgtcgaaata
     6001 aaaaataaac aaaaagagta agatgaacct ctctatagag tgctcgtctt gctctttttt
     6061 tgcgaaaaac aaataatt
//
LOCUS       DAKCAA010000103         5936 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000103 DAKCAA010000000
VERSION     DAKCAA010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.106"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            3..761
                     /locus_tag="OUE31_002562"
     CDS             3..761
                     /locus_tag="OUE31_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCU0223526.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(847..1587)
                     /locus_tag="OUE31_002563"
     CDS             complement(847..1587)
                     /locus_tag="OUE31_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0223527.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            1648..2901
                     /locus_tag="OUE31_002564"
     CDS             1648..2901
                     /locus_tag="OUE31_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCU0223528.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLIGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            3223..3450
                     /locus_tag="OUE31_002565"
     CDS             3223..3450
                     /locus_tag="OUE31_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCU0223529.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            3573..3899
                     /locus_tag="OUE31_002566"
     CDS             3573..3899
                     /locus_tag="OUE31_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCU0223530.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            3967..4680
                     /locus_tag="OUE31_002567"
     CDS             3967..4680
                     /locus_tag="OUE31_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCU0223531.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            4990..5841
                     /locus_tag="OUE31_002568"
     CDS             4990..5841
                     /locus_tag="OUE31_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCU0223532.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
BASE COUNT         2049 a          975 c         1170 g         1742 t
ORIGIN      
        1 aaatgaaaaa aacaattgca ttaagtaccg ttctagctgg aagtctatta ttatgtacac
       61 aaagtgtttt tgctgagaat aagagctcag ccactacaga aggaacgatt tctgtgacca
      121 aaccagatgc tgcaaatcct gaagacgttg ttccagttcc tcctgttgat ccaaatgatc
      181 ctgatactcc ttttacacct gacgaaccaa atcagggaac atccggatta ctgacgattg
      241 accaagctcc agatcttgat tttggaacaa tcaagttagg tacagcaaaa acagtatatg
      301 ctgcattaca aagcggaacg gacagtactg gagcacaaac acaagtacag aatttcgtac
      361 aagtaacgga taaaagcgga aattatgccg gttggaaatt atcagtcaaa cgaacagaat
      421 ttattggtac aacatctgat acgaataaac taactggttc aaaggtgaaa ttcaaaaacg
      481 ccgtgattcg aaatagcgca actaatagca gtggaatgcc atctaccgtt tctggaactg
      541 gcgctgaagg aatcgaaatc ccagcagatc aggcagtaga tctagtaact gcaggagcaa
      601 atgaagggat tggcacatgg atttattcat taggagagaa tgtggaacaa gggagacaat
      661 cagtggaatt atttgttcct gtatccaatt atgctgtaga caactacgtt tcaacattca
      721 catggtcgtt aacagatgct cctacagaag aggaagcgta aaatcatatc aacgacttca
      781 gggagtggag ccgattcaag gcccactccc tgaaatctgc tatgcttacg tctcagctct
      841 tattcatcaa ctcgaagcag ttttttggaa gtcatggaaa cgttcctttg tcttttcaaa
      901 gatctttcga ccaacgagta aggagtcacc gttgaaaaat tctaacacat aatgagcaga
      961 atcaattttc tgcaattgcg ataagttgat acagtaagat tttaaaagta aaaagtaagc
     1021 atacttttct aactctgtct tcaattgttt taaagaagta ttcactaatt tatcttctgt
     1081 agttgttttg accataactt ggtttttcaa acctttgata ctttcaatat ataaaatttc
     1141 ccgaggatac aggacgagac ttccaccttt ttgatcaata aagattttat cgacatttac
     1201 gatctgctgt tctttccaat tgatctgttc tagcacttga cgaatttgtt cagataaatt
     1261 cctgtctttt ctgatatatc caatcggaag gattttccga ttgatgatct ctactgcaaa
     1321 attcgtataa gcggtgaaaa aaacaatatt actatgtgca ttttttttac gtatttgttc
     1381 ggcgacatca atacctgtga gtgattgctt caagtcgata tcgataaaga aaacatcgtg
     1441 attatcaata gtgcccaact ggatcaactg attgatttga gagatagaag tgagctgcac
     1501 gatattctcg atatgatgat tgaccaattc tctgatgatc cattcgctgt gaaactggtt
     1561 atcttctatg ataaaatact ttttcatatg caggctccta ttaaaaaaat atgtgtacat
     1621 tttgaaacaa aacaatggag gaataagatg gtcgcaacag tgacacttta tttgaccttt
     1681 actttgattt tagatttagg tatctattta ttcttttcga aacaactgct agtaaaaaac
     1741 agctttggtt gtatagcttt gatggtggtg acacttttac ttcctatccc taaagtgagc
     1801 tttccttacc taattggctt attattgatg tttctttttt attttactac gaaaaacctg
     1861 tttatcagct gtttgatcag taatcttttt tttgctatca ctggactcag cttttttctg
     1921 gtttttgatc tgatggatta tttaggaaag agacatcttg gaacagcaag tttttttgca
     1981 ctacttatcg catttatttt ctatctatta gtaaaaagta tagacaaaca gacgagattt
     2041 ctcaacttgc tttttactta tccaactgaa cactattttg gaggtatttg tattttatta
     2101 agctggggcg tgatttactt ggtattggga agtgttcact tccgctcatc taattatctg
     2161 cttctatctc ttttgtcgat agtcatcagt tttttttctt tgtttttttc cattatgttg
     2221 atcagtttcc aagtaaaaga aagacaacat caggaatcgc ttcaactgta tcaaataaat
     2281 gaagaatatt accatcatct agaggaattc aaacatgatt ataaaagtct actgttttca
     2341 ttaaaaatta ctcttcagga aaataaaaaa gaaacgttgg aatttttaga aatattagaa
     2401 gatcattctg cagctatttt tgaaaaaccg caaatacaac agctaacaaa tattgtatcc
     2461 ccagctgtca ggggtgtctt tttaaaattt ctagaaaaag cagaatcgga gaaaatcccg
     2521 atccaagtag ttattcctgt cgaagtgaaa acaatcccga ttgatctggt tgtttttatt
     2581 cgctgtttat ctatttttat ttctaacgca ttcgatcatc gtgtagccga tcagagtccg
     2641 attacgatca atctgctgga agaaaaagag ggatcacgtt ttagtatagc gaacaaggca
     2701 aatccaacga atttgacgct atcggagatg gtcaaaagag gaaaaacctc taaaaaaaat
     2761 ggcgggttag gtctatacag tgcgaaaaaa atgttggatg tttacgaaaa tgcagaacta
     2821 aaaatcgaat tttcaaaaca gaatcactat ttttttgtag aaatgtatct ggcatctaga
     2881 aagagcaaat cagcctactg acttactgtc aaaggataag tttgaggaaa gtctacacgg
     2941 agatagagac aacaacacag catattcaaa agaaacagaa gcgtgatgac cgttgtcacc
     3001 cttctgtttc ttttgctatg tagttaaaca aagtagttga cacttccgct acttagtatt
     3061 agtacgaaag tatacttcat gatactaagt agataagaag tgaaaagcgg aacccacgat
     3121 cgtcaaaatg ctaactgctt tgcttacacc agataaaggg aagagcaata tcgcttattt
     3181 taggcgtgga gaagcaagca aatccctacg atcacaaaaa aaatgctgac ccagcagtta
     3241 agagagttag aacaagatga aagtatccat cgaaaagcct ataaccaagt cccgcctaaa
     3301 gtagagtact cgctcaccga agaaggaaaa tcattaagag agattctagt agcgttgtct
     3361 gtttgggaag aagaacgtat cgaaaaacaa aaagcctcaa gggaagaaga cacgctactg
     3421 catacacatg gtggctacct aaattattga ttttctatga catttatttt aaataaaaga
     3481 aaacaggagt ttttttaaaa gcatcatcta ttttttatgt aaaaaaatgg tatgattaat
     3541 caagtaagaa gtgattggaa gaaggcaagc aaatgaatag tatggaaaaa gtcaaccagt
     3601 ttagagatga acgtaattgg cgacaatttc ataacgaaaa agatttggct atctctattt
     3661 ctttggaagc atctgaattg ttagaacttt ttcaatggaa aacgccggaa gaagtaaaag
     3721 aaacacaatt agaacgaatc aaagaagaac tggcagatgt attgatctat tcatacatga
     3781 tggcagacaa ccttcacctg gatctagatg agatcattga agaaaaattg atcaaaaata
     3841 atttgaaata tcctgtagaa aaaagcgcag gtgtacgaaa aaaatacaca gagttgtaga
     3901 aatgtgtcat tcggctgttg gaaagagcaa aagaaaaaca gtaaaatgag tctggaggga
     3961 gagaaaatga aaaaaaaagg aaaagcaaaa agatggctag tcaatatcct cttgttcctc
     4021 ttgttattag taggactagc tttgattttc aatgaacaga tcaaggatta ttttgtcaga
     4081 gagacaggag ataaatatgc tatagcgaat gtaacaaaag aagatctgaa aaagaataac
     4141 gataaagatg tcagttttga ctttgatgcg gtagaaccaa tgacgacaga aggggtcatg
     4201 aggtcgcaaa tgagaggaac agatctacca gtgattgcta gtatcgcagt cccttcagtt
     4261 tcaatcaatt taccggtttt caaaggcttg gataatacgt cactacttta cggagcagga
     4321 acattatctc cagatcaaga aatgggaaaa ggaaattatg ccttagcaag ccatcgtgca
     4381 acgaaccctg aattgctgtt tacaccgcta gaaaatttag agatgggtgc caagatctat
     4441 ttgacagatt tagaaaatgt gtatacatac aaaacatttt ttaaagaaaa agttgctcct
     4501 acagataccc aattactgaa tgaagtcgag ggaaaagaaa ttgtcacact aattacttgt
     4561 ggcgacatgg acgccgtcac gcgactagtt gtacaaggag aactggaaag tgttacatcg
     4621 ataaaagatg cgacagatga tatgagatct gctttcaatc tagagacaaa aacattttag
     4681 gatactggga cataagtcgt tacagattaa aaacagccaa aggatatgaa tcgataagga
     4741 aaaaccaatt tgctgaaaaa aagagaaacg caaagaggtg catctctgat ttggttgttt
     4801 tctagataga cttgtgttcc agttttttta ttttttatat gaaaaggttt gcataaataa
     4861 aaattcgatg gtatgatgat tttgaataag aaatggattg ttactgtacg gcaggcaaaa
     4921 ccagaattca gctaagaaac agtaggcgaa ttctaggttt ttttattttt cttgagaggg
     4981 cgaagcaaaa tgaaaattga taaaattttg aataacaatg tcgtcatttc gaaaaatgga
     5041 ttcggggaag aagtcgtttg tatgggaaaa ggactagctt ttcaaaaaaa gattggggac
     5101 gagatttcgc cagaagcggt ccaaaaagaa tttgttttaa gagattcttt tgctaaaaac
     5161 caattccagc agctgatggc tgatattccg gcagaggaga tcgaatgggt caaacaagta
     5221 gtcgaactgg ctgaagataa actaaaagtt gaattttcgc ctaatattta tctgacattg
     5281 accgatcatc ttcattatgc gatcacacga gcaaaagaaa atatccaact gcctaatcca
     5341 ttattatttg aaacaaaaaa attttatccg aaagaatatc aagcagcgaa agaggctctt
     5401 ttgttcgtga aacaaaagac gggtgtggaa ctttctgagg atgaagccgg ttttattgcc
     5461 tttcattttg tgaatagcca acaaggaaac gaagacatgc aagtgacgat gaccgctacc
     5521 acaatggtaa gagatatact gagtatcatc agtaaattct tcggcatcgt gttcgatgaa
     5581 gaatctttga attatcagcg tatcattact catctgcagt tttttgccca gcgttatctc
     5641 aaaggggaag gatctgacga gcaagatgaa tttctctacg cattagttca aggaaagtat
     5701 ccaaaagcgt ttcattgtgt cgaacggatc aatgagtatc ttcgacaaac gcaaaaacag
     5761 gaaatgggga tcgcagagca gatttattta acgattcata ttcaaagagt agtaagtgag
     5821 aaaaaaagca tccaatcata aggattgtta ctgtatggca ggcaaaacct ggattgaaaa
     5881 aataggttca cgaatgtttg tgactgtttt tttcaatctg ggtttttatt ttttaa
//
LOCUS       DAKCAA010000104         5924 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000104 DAKCAA010000000
VERSION     DAKCAA010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.107"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(75..1169)
                     /locus_tag="OUE31_002569"
     CDS             complement(75..1169)
                     /locus_tag="OUE31_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCU0223533.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            1358..2119
                     /locus_tag="OUE31_002570"
     CDS             1358..2119
                     /locus_tag="OUE31_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCU0223534.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(2234..2674)
                     /gene="fabZ"
                     /locus_tag="OUE31_002571"
     CDS             complement(2234..2674)
                     /gene="fabZ"
                     /locus_tag="OUE31_002571"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCU0223535.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            2894..3649
                     /gene="fabI"
                     /locus_tag="OUE31_002572"
     CDS             2894..3649
                     /gene="fabI"
                     /locus_tag="OUE31_002572"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HCU0223536.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(3759..4772)
                     /locus_tag="OUE31_002573"
     CDS             complement(3759..4772)
                     /locus_tag="OUE31_002573"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HCU0223537.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            4937..5857
                     /locus_tag="OUE31_002574"
     CDS             4937..5857
                     /locus_tag="OUE31_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCU0223538.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
BASE COUNT         1806 a         1180 c         1063 g         1875 t
ORIGIN      
        1 ctataaaaaa acaaaataaa aaagcagaaa taactggcta tttctagcgg attatttctg
       61 caataactaa ttatctattt tttattttca attaatttaa agcttgacca tggtttcaaa
      121 aagtcaagga ggaataattc gtcatcggag attcttccta caacattgac acgtccgtcg
      181 tttttcatat ccttcaaggc gatttgtgtt tctcctttgt attgaccgta cccttcattg
      241 tcaatcagta catccccatg atgcatatct cgcgtattat gaggcgggaa atctttatct
      301 ttgtagtata cacgagtcat cgttgaacga aggatatatt ctgagcgatc ccctcgataa
      361 ctatgaaggt tatcaaacaa gcagattcgt tcgttttctg taataccttc ttccgtatct
      421 actttcaatg ttggataatc cgcgttaaat gcttctgcca tttctttcaa ttcttcttca
      481 cttgcgtacg catttccaat agaaatatca tcaatcaatc ctgtaaggat taaatgcttc
      541 acttgtgtcg caatttcaag atctcggtgg tcttccagcg tgcacaagcc atcttgcgta
      601 ggccaagggc caaactcagc agattgcgaa ttgacgaatg ccatcgtatt caaattatat
      661 tttctgaatt tttctgaaca aaaaacaaag tgttcgtatc ctaaaccaga gtatcgatga
      721 ggataaaaat tatgagaacc taataaatta tccgtgtttg gcgaataact catgatgttg
      781 tcaacgtaat tcgtgcccga actcatattg atctcgattt tgataccaaa aggattgcgc
      841 gtcatttttg cttcttctgc tcctgtgaat ccgatatcta agcggacccc gtaggcaccc
      901 atcttatgga aaaaagataa gtcatcgtaa gaaatctcca actgttcaaa taacgctgga
      961 ttgatatcaa ccattacttc catgcctagg ctattcgcgt aatcaactac ttctttaaat
     1021 tctgaaagaa ctttttcttt atcatcattg atctgcagca aactggtaaa aacccgttta
     1081 tacccatact tatgagctaa atccaagtac gctttgtcct tttcaaatgt tgaccgttct
     1141 ggataaatcg agattcctaa ttttcccata ttaccatttc ctcctgcatc ttttcgtttt
     1201 tgtatccact tacattatag caaacacaaa gtaaatggtc tacacctttt ctttttcttt
     1261 taaaataaat gataaattcc aataatttaa gtaggtattt tccctctatt ttgttatcat
     1321 taaagataac aaaatagtaa attggaaagg aacagttatg aagaaaaata aagttatttt
     1381 aagtattagt ttagcagcag cattgctgtt tgctgctggt tgttctgcaa acaacacgac
     1441 ttcttctagt tcgtctacag aaagttcaaa aagtacatct actgcggaaa gcacgactgc
     1501 cagtagcgtc gatttgaacg cattggaatt accacaattg acgaaagatg tcgccgaaaa
     1561 tgaagatctg gtcgaaatgg tgacgaataa aggcacaatc aaaatcaaat tatttcccga
     1621 acacgcacca aaagcggttg aaaactttat gacacatgca aaagacggtt actacaacgg
     1681 actgactttc catcgcgtca tcaaagattt catgatccaa ggtggcgatc ctaaaggcga
     1741 tggcactgga ggggaaagca tttggggaga aggatttgaa acagagatca acaaccacct
     1801 ttataatata agaggtgcgt tatctatggc tcgctcacaa gatcctaaca gtaacggcag
     1861 ccagttcttt atcgttcaaa atacagatga tatgcatgat ggtcttttaa aagacgacta
     1921 tcctcaagca atcatcgacg cttataaaaa cggcggttat ccttcactag atggccatta
     1981 tactgtcttc ggccaagtga ttgaaggaat ggatgtcgtg gatgctattg caaatatcga
     2041 aacagatagt tcagacaaac caaaagaaga agtaaaaatc gataaaatca atatactgca
     2101 agaagcaaaa caaaaataaa aaaataacgt ctgaatcctg catagatgac aacgtatgct
     2161 aggattcagg cgtcttcttt ttacataaaa agcaagtaag cttccttttg ttttgctata
     2221 tcaggtttta tagtcaagca ttttggttga cgatgaacgt gaactcgcac tcacagactt
     2281 ttttatcatc tacatatgct gcagataacg ctgtaccgac tgatcccttc attttggtga
     2341 tttcaaaatg acatttcagc acatctcctg gaacaacttt ttgacggaat ttggccttat
     2401 tgatcccacc gatataagct ctttttccta gaaactcttc tgattttagg ataagtatcg
     2461 aacctgcttg tgccagtgtt tctagaatca acgcacccgg catcactgga ttgtcaggaa
     2521 agtgaccttg gaaaaaatct tcattgattg ttacattttt tgtcgcaacg atcttttttc
     2581 ctggttctaa agtatctaca taatcaatat aacaaatagg ataacgatta ggaatcaatt
     2641 ccattacttc agtagcagat aatacgtaag acataattaa actccttctt tcaggcaatt
     2701 gccattttca ttactttgac tatcaaagta tcatattcct aaatatttag caatcttttt
     2761 ttaatttaag aaaaaatagt ttgacaatca aaacattttg actaataatt aagaaatcaa
     2821 gaagttattt tagctattat tctctatttt tttacgacta tcaaattttt atcagaaaca
     2881 aaggagagtc attatgtcat ttctagaagg aaaaaaaatc gtcattatgg gcgtcgctaa
     2941 caaaaaaagc attgcttggg gttgtgctga agcaatgttg aaacaagggg cagaaattat
     3001 ctatacttac caaaatgaac gaatgaaaaa atcattagtc aaattggtcg gcgaagaagc
     3061 attcactgta gaatgtgatg tttctagcga cgaaagcatc gaaaaagcaa tgaatgccat
     3121 cggtgaatat gctggggaga tccacggcct tgtccatgca gttgcttacg ccaacaaaga
     3181 agaattgtcc ggaaatgtgt ctgatatttc cagagacggc tatcaattag ctcaagatat
     3241 cagcagctac tctttaattg ctgtatcaaa atacgcacaa ccgtttcttg caccaaacag
     3301 cgggatcgtt agcatgactt atctaggttc agaacgcgca atcccgaatt ataacatgat
     3361 gggtattgcg aaagcttctc ttgaagctgc tatccgttat ttggcagctg agttctcgcc
     3421 taaaggaatt cgggtcaatg gaatctcagc tggggcaatc aaaacattag ctgtcacagg
     3481 tgttaaagac tatcaaaaac tgatccagtt atctgaatct cgtacgcctg atcagcaagg
     3541 tgtgacgatc gaagaagtcg gtaatgcttg tgctttctta atcagcccac tttccagcgg
     3601 aatcatcggt gatattatct acgttgacaa aggtgtccat ctttcataaa cttttgttgc
     3661 attctttaaa gtaaaacata taaaaatcag gaaaaaactt tttaaagtct cttcctgatt
     3721 ttttcttttt acgttttttt caactcatta ctttgaaatt attccacgac ttcaatccag
     3781 ccttctggtg cttctatgtc tccaaattga atacctgtca attcatcata caaccgtttt
     3841 gttactggtc ctacttccgt ttcactataa aatacatgaa gattgttatt gtgataaatc
     3901 ccaccgattg gagaaataac agccgctgta ccacatgcac cagcttctgc aaattgatct
     3961 agatcatcaa tgaaaatatc tccttcaatt gcttgcagtc ctagtcgttc ttcagctaac
     4021 tgcaacaagg aatatttcgt gatacttggt aagatagagg gcgattgcgg agtgatgaat
     4081 tttccgtctt ttgtaattcc aaagaaattt gctgcaccta cttcttcgat tttcgtatgt
     4141 gtggctggat caagataaac acaatctgag taatccagtt cttttgcttc tgttcctgga
     4201 agtaaactcg ctgcgtaatt tccgccgact tttgctgcac cagtcccctt aggagcagca
     4261 cgatcgtaat cagatacaat aaaattcgtt ggttttagtc cacctttgaa atacgctcct
     4321 actggcgtac agaagacgac aaataaatat tctggagctg gatggacacc aatgttttca
     4381 ccgaccccaa tcagtaaagg gcgcaagtat aatgtagcgc ctgttccata gggcggcaca
     4441 aaatcttcat ttgcttttac cacttgcttg acagcatcaa cgaacatctt ttcagggacc
     4501 attggcatca gcaatcgtct agcactttga ttcatccgtc gactattttg ttcaggtcga
     4561 aagagattga ccttgccgtc ttttcgacga taagctttta gaccttcaaa acattgctga
     4621 ccataatgaa gcgctggaga gccttcatga atcgtcaggt aattatcttc tgtcaattct
     4681 ccttcttccc attgtccgtc tttccatttg gcaataaaac gccaaggagt tttgatataa
     4741 gaaaaaccta gattgttcca atcgatttgc atatacttac caccttcgtt attttctcca
     4801 cattttatca ttatccatat tatttgtcat tttattttca gcttttttcc ttcattatag
     4861 ttatttttgc tatttccttt tttgaaaact tcttggtaca atacagaaag aatcaaattt
     4921 tagaaaagag gattttatgt tttcattatt agcaactgcc ggtacgacag actcttctgg
     4981 cgagacattg acagatcaag ctgtcagcaa agtaaatgcg tttcagcggt tttgggacgg
     5041 gattgattgg gacgccattt tggctgcctt tatccaaaaa agtttatatc tgattttttt
     5101 gatcgtcctt ttttggattc ttcaccgtgt gggaaaatat ctgattgata agtcttttaa
     5161 tcagtattct aaaaaagcca ttctaaacga gagccgctta aagactttac atagtctttt
     5221 aaatactatt tttcattata cccttggttt cttttttatc tatgcaattt tatctgctat
     5281 cggtgtgccg atcggatcac ttttggctgg tgccggaatt gcaggtgtgg caatcggtct
     5341 tggtgcccaa gggttcatga gtgatgttat taccggattt tttattatca tggaacaaca
     5401 gatggatgtt ggggactaca tcaagctagc aaacttaacg attgaaggaa ccgtcgtatc
     5461 tgttggtatc cgtacccttc agctgaaagc aacggatggt actgtccatt tcatcccgaa
     5521 tcgaaacatc accacgatca gcaatctctc tcgtgcaaat atgcaagtac ttttagatat
     5581 tcggattgtt cctgaagaag gatatgacaa aatctatgag atcattgatc gagtaaatcg
     5641 tacattagct gaaaaatacc aagaagagct ccaaactgaa ccttctatct ttggattagt
     5701 ggatcttgga aacagcaatt ttgcgattcg tacggtctgc tacgcattga acggaaaaca
     5761 atatgcctta aaagaagagt tcttgagctc ctatgtcaaa gaattgacag cttctggttt
     5821 cacgattccg aacagtccaa ttgctgtcgg aaaataattt ggacaaacga tgcaacgaat
     5881 ctcactaaaa agagcgtggg acaaaagtaa agaacacttt tgtc
//
LOCUS       DAKCAA010000105         5862 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000105 DAKCAA010000000
VERSION     DAKCAA010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.108"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(99..1229)
                     /locus_tag="OUE31_002575"
     CDS             complement(99..1229)
                     /locus_tag="OUE31_002575"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HCU0223539.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="OUE31_002576"
     CDS             complement(1878..3080)
                     /locus_tag="OUE31_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCU0223540.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="OUE31_002577"
     CDS             complement(3140..3343)
                     /locus_tag="OUE31_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HCU0223541.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="OUE31_002578"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="OUE31_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="OUE31_002579"
     CDS             4880..5692
                     /locus_tag="OUE31_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223542.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1735 a         1209 c          938 g         1980 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa tt
//
LOCUS       DAKCAA010000106         5510 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000106 DAKCAA010000000
VERSION     DAKCAA010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.109"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..382
                     /locus_tag="OUE31_002580"
     CDS             <1..382
                     /locus_tag="OUE31_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="2-dehydro-3-deoxyphosphogluconate aldolase"
                     /protein_id="HCU0223543.1"
                     /translation="NSLRYLEFREGAFDFQTSQQNLLTIPGAMSPTEIFKMFEMGADI
                     VKVFPANCLGPEYFNQVQAPLGSLPLMAVGGVDQTNAQNYLNNGASYVGIGSKFFEKS
                     AVHQLNYERLMELAESFIDSLRVE"
     gene            complement(776..1783)
                     /locus_tag="OUE31_002581"
     CDS             complement(776..1783)
                     /locus_tag="OUE31_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCU0223544.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLTVRKSFIPKEE
                     V"
     gene            2250..3656
                     /gene="lacG"
                     /locus_tag="OUE31_002582"
     CDS             2250..3656
                     /gene="lacG"
                     /locus_tag="OUE31_002582"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCU0223545.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            3679..4002
                     /locus_tag="OUE31_002583"
     CDS             3679..4002
                     /locus_tag="OUE31_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCU0223546.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVREGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLRELINDFVELYKE
                     KFAKA"
     gene            4013..>5510
                     /locus_tag="OUE31_002584"
     CDS             4013..>5510
                     /locus_tag="OUE31_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCU0223547.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVVATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFS
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGS"
BASE COUNT         1735 a          822 c         1131 g         1822 t
ORIGIN      
        1 taacagccta agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca
       61 gaaccttcta acaattcctg gggccatgtc gcccacagag atattcaaaa tgtttgagat
      121 gggtgctgat attgttaagg tgttccccgc caactgtctt ggaccggaat atttcaatca
      181 agtgcaagcc cctttaggaa gtttaccttt gatggctgta ggaggggtag atcagactaa
      241 tgcacaaaac tatttgaaca atggagcctc ttatgtagga attggttcaa aattttttga
      301 aaaaagtgct gttcaccaac taaattacga gaggctaatg gagttggctg aatcttttat
      361 agatagttta agagttgaat agaacccatt tgcggaatac aacttgtttt ataatatggc
      421 gttatctgta taaaacatag tatcacagtg aatgagattg aactggtaga ttgatttttc
      481 gaccagttct ttttgcgcgc tctgatgctt gatatattcc caacgagata aaaaatcccc
      541 caagatacta agatgaagcg tttatccaac ctcatactta gataaaaagg aggaaatgtt
      601 ctgaatgata aacaaaaatt agcgcgcaca atttggcgat gaaaaaatca tattgtattt
      661 acgtcaaaat atcaccatca aattatttat ggaaaacata ataggcataa acccgattgc
      721 tcggctacta tgtggacaca attatagttt taaagataag tttcaattac ttattttaca
      781 cctcttcttt agggataaaa cttttcctaa cggtcaattt tgcgccgatt aatgttttct
      841 ttgatatgtc ccgcgaatat accagttgat cacttaataa atctacacag gttttagcta
      901 tctcttcgat atctatctta aaagttgtaa gtggtggtgc aacgaatttt gcgatgtcgt
      961 catcattaat acttattact gccatatctt tagggatgtt aatacccaat tcatggcagc
     1021 cctgaagaac gccggcagct atagtgtcag atggtatgaa acatgcctcg ggcatatctt
     1081 catttaactc agctttcatt ttaagagtta attgataccc ttcgtcaaca gtaaatgatc
     1141 cttgggagaa aatatacttt tcattgagta gtccgctctt ttctaaatga tatcggaagg
     1201 catattcacg gctatcaatc tcttctttac ccgtttctag gttaaagaaa tttcctccaa
     1261 taaatccaat ttttgtgaaa ccttcattaa taaagtagtt aattgcttgt ctggccattt
     1321 cgtggaaatc aggttctaca gtatcgaagt gttcaggtaa tgggtttatt cctcggatta
     1381 cccccttata ccctttttga tttaagtagt acaattcctt ttttgtcaat tgtcctattg
     1441 cgataaatcc agtaatatcg tcaggaatgc tttttacacc atcgttttta gagatgaaaa
     1501 tcaaatctag attagctttt ttactataat ttttcaaatc atctttgaca tgttgatagt
     1561 agacatcctt ttttaactgt tcctctgaga tccaaaaaag aatggcaatc ttgtacagag
     1621 tagtcttaat ttttgtcaga tcatatccta aagatttggc tgtaacgatt attttgtttt
     1681 tagtatcaga tgtaatagag agtgactcat cacctttaaa aagtcttgat atagtagccg
     1741 ttgagtaacc agattttttt gcaatatctc taatagtaac cattgttcat cctcctaggg
     1801 atataataat ccttttcttt gttaaagtaa atcgaaactg ctcttttagt aacttaaatt
     1861 actttttcta gcaggaaacg aaactctgat atcagcagag agcctaatcc attaacagag
     1921 aagattgaat cgataatgga tagccacttg gagaatgatt agtaggtggg attgatttta
     1981 gtgggaatca gtccgttttc ttgtttcgtg taaattaaat tagtaaaaag ataaatttat
     2041 tttacaaaaa aacgtttaca aaacggtttt tgaatggtat atttatttta catcaaggga
     2101 tataagtgct tgtatatcgc aataaaatag atattcgagg tcggtttttc gttgtgtaaa
     2161 aaaatttact tatacatgtt aaaattatgc tgaggtgatt tatggattat tggcatattg
     2221 atcaaactaa ttttcaagga gagattaaaa tgaattataa aactttacca gaagacttta
     2281 ttatgggagg agctacggca gcttatcaag cagaaggctc tacaaaagaa ggtggaaaag
     2341 ggcaagtagc gtgggatact ttccttgtag aaaagggacg ctatactgct gatccagcta
     2401 gtgattttta taatcaatat ccagttgatg ctgaattatg caaaaaattt aaaattgata
     2461 gtattaggat gtctattgca tggagccgta tttttccaaa aggctatggg gaagtgaacc
     2521 aaacaggagt ggaatattat cataaggtat ttgctgaatt gaataagcat ggtattattc
     2581 cttttgtaac tcttcatcat tttgataccc ctaaagaact atttgataat ggagattttt
     2641 taaatcgaga aaatgttgaa catttcgtaa actatgcaca gttctgtttc gatgaatttt
     2701 ctgaggttca ttattggagt acatttaatg agatttatcc agttgcttca aatcaatatt
     2761 tgatcggatc gtttcctcca gaagttcaat ttgatataga gaagactgta acttgtttac
     2821 acaacatgat gtatgcgcac gcaaagacag taaacatttt taaagatggt ggatataaag
     2881 gggaaattgg tgttgttcac tcgctagaga caaaatatcc agcaagtgac aaagaagaag
     2941 ataagcatgc tgcgaaatta gatgatgcgt tatcaattaa gttcttatta gatgctactt
     3001 atttagggta ttactcagat gaaacaatgg cacatattaa tgagatttta gcagcaaatg
     3061 ggcaatctgc agatattgat tctaatgatt ttagagagat gaaaaaagca gcaaatcgaa
     3121 atgattttct tggtatcaat aactatggta gccattgggt taaagagtac aaaggagaaa
     3181 gcacacttca ctacaacact accggagaaa aaggtagcca agtctattgc attaaaggga
     3241 ttggcgagag aatcgtgcgt gaggatcttc cgaaaaccga ttgggattgg atcatttatc
     3301 caaaagggtt atatgattta cttgtacgaa tccaagacga atatccaaat tataataaaa
     3361 tatacattac tgaaaacggg ctagggtata aggataattt tgaagatggg attattctag
     3421 atgatgatcg aatcgattat ttacgccagc attttaatgc gatttccgat gctatcaaaa
     3481 tgggagttaa tgtaaagggg tatttcattt ggtcattaat ggatgttttc tcttgggtta
     3541 atggatacac taagcgttat ggactattct atgtagattt cgatacacaa aaaagatatc
     3601 cgaaagagtc tgcatattgg tataaatttg ttagcgaaac aaaaacgata atataaaaat
     3661 agttaggagg gcaaggaaat ggataggaaa gaattgcaat tattaggatt tgaaattgtt
     3721 gcttatgcag gagatgccag aagttcatta ttaacagtgt tgaaggaagt gagagaaggt
     3781 aattttgata atgttgaacg attattagcg gatgctgatg aaaatttaac cttagcgcat
     3841 aactcacaaa cgaaatgttt agctgaagaa gcgtcaggga acgaaatgga agtaggcgta
     3901 atttttattc atgggcaaga ccatttaatg acaacgattc tattaagaga acttatcaat
     3961 gattttgttg aattgtacaa agaaaaattt gctaaagcat aggagaagaa aaatgaatac
     4021 gattattaag caaattgaga agggaaaacc gttttttgaa aaaatctcac gtaatattta
     4081 tttaggggca attcgcgatg gctttttaac tgctatgcca gctattctat tttcaagtat
     4141 ttttattatg attgcggctg ttccagaagt atttaacgtg acgttaccag aggcattctc
     4201 gacgtggctt tggaaagttt atggttattc aatgggatta gttggtcttt tggttgttgc
     4261 tacaacagct cgatgtttag ctaattcaat gaaccgtcaa ttatctgatt caggtaagca
     4321 gattaatgaa gtttctgtta tgttagcgtc aatttgtggt tttgtaatga tggcagctga
     4381 tcaaattgat ggtgggatag ctactgatta tttagggaca aagggattat tagcagcttt
     4441 cgtttctgcg tttgttactg taaatgtgta taaattctgt gttaaaagag atttgacgat
     4501 ccgtatgcca aaagaagttc ccggaacaat cacacagatg tttagagata ttatcccctt
     4561 ttcaattgca gtatttattg ccgttttgat tgatacggga gttcgtcaat tttttggaac
     4621 atcatttgca gcaggtgtaa ttcaattatt gcagccatta tttagtgctg ctgatggata
     4681 tgtcggtatt gcaatcattt ggggagccat ggcaatgttc tggtttgttg gtgttcatgg
     4741 accatcgatt gttgaaccag cgattgctgc aattatttat gcgaacgtag aaactaactt
     4801 tgaattattt aaaaacggtg cacaagcctc aaaagtatta acagttggtc taggaaactt
     4861 tgttggaacg atgggtggta ctggagcgac actagttgtt ccttttctgt tcatgttgtt
     4921 cgctaaatca aaacaattga aagcagttgg taaagcttca tttattccag tttcgtttgc
     4981 ggtaaatgaa ccgttactat ttgctactcc tattattttg aatccgtact ttctaattcc
     5041 atttttatta gcaccaatcg ctaacgtatg gatattcaaa ctttttgtcg atgtcttggg
     5101 gatgaatagc tttatatccg tattgccttg ggcgacgccc gcaccgattg gcttggtttt
     5161 aggaaccggg tttagtgtgt tggcgattgt attagcggta gtattgattg ttgtcgatgc
     5221 gattatttat ttaccttttg ttaaggccta tgattctgaa ttagtagaac aagagttaaa
     5281 aaacattgct gcagaagaag taaaagaaga attggtcgaa gaaatccaag aagttggtgc
     5341 aactgcggca gttatagttg atgaagcaaa agcatcggtt ggtgaaggaa agcgcgtttt
     5401 agtactttgt gctggtgccg gaacgagtgc aatgttggct aatgcattag aagagggcgc
     5461 aaaagagaca ggtgttaatc tttctgctaa agcaggagct tatggttctc
//
LOCUS       DAKCAA010000107         5486 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000107 DAKCAA010000000
VERSION     DAKCAA010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.110"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(80..829)
                     /locus_tag="OUE31_002585"
     CDS             complement(80..829)
                     /locus_tag="OUE31_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCU0223548.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            1015..1719
                     /locus_tag="OUE31_002586"
     CDS             1015..1719
                     /locus_tag="OUE31_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCU0223549.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            1759..2316
                     /locus_tag="OUE31_002587"
     CDS             1759..2316
                     /locus_tag="OUE31_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCU0223550.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            2324..3463
                     /locus_tag="OUE31_002588"
     CDS             2324..3463
                     /locus_tag="OUE31_002588"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCU0223551.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEIYSLLSEKEQENFDEYAYFVNTAIDRQ
                     SLGKVLGGKMISVVEPYYEWIMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAA
                     HAAVAYLGALKGYKTIQEAIQNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKT
                     LNRHGNQKLSDEITRVGSSPIRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYR
                     NLADPEAEQLRRMIVNDGLKATIKKISRLEGKLLNEVVAAYESQI"
     gene            3475..3906
                     /locus_tag="OUE31_002589"
     CDS             3475..3906
                     /locus_tag="OUE31_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCU0223552.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            3920..5365
                     /locus_tag="OUE31_002590"
     CDS             3920..5365
                     /locus_tag="OUE31_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HCU0223553.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
BASE COUNT         1829 a          816 c         1144 g         1697 t
ORIGIN      
        1 tttatttcaa aactttattg cgtgtttctt ttttagattt tttatatctg ttgctttagt
       61 agttaccaat agttttcgct taatcaatca aaacgatttt ttgtttattg tattctttac
      121 gaaccttttc aggaatttct tctgaaataa gataggtaag gtcttcaatt ggaccgacga
      181 tatgattact gatggtgccg aatttatcat tagttatcat cccaagtact tcagtagaaa
      241 tacgtatcat ctcacgttta atgtcggatt cttgcatagt tggcacgctc gttccaacat
      301 ctagatctat gttataaata cccataatat aaaggtcggc tcgaatgttt tgtagttgct
      361 tataagcttg taccccaata ttgatcatag attgtttata aaaagtaccg ccaatattga
      421 taatttccaa attaggatgc tgtgctaatg ctatggcaat cggcgggcta ttggtaatga
      481 ttgttgcacg aaaatcttgt gggatttctt ttgctaaagc caagttagtt gtacttccat
      541 caatgatgat gacagattct tcttttaaaa aagggagggc tttatgagct aatgcagttt
      601 tttgttcgct agctacagtt tctcggtagt taaaattggt aattggcgga ccaacacgta
      661 aagcgccgct gtgtactctt tttaagagac cttggctatc caaatctttc aaatctcgtc
      721 gaatcgtgtc ttcggataca ttgaaacgtt gacttaaatc actagcgata actttttgtt
      781 ctgcgtttaa taaatctaga attttttgat gacgttctaa tttcaacatg ttgcgtgctc
      841 cttcttattt attcttgttt atcatgtcat ttatgcgttt ttatgtcaat aatttccgtt
      901 tttaatacac taaaaaggca taaacaagca aaaacaaaat atttttatgc agttttatgt
      961 tgactagtat ttgttaagcg gttacaatga gggggtaatt aaaggaggga atgtatggag
     1021 aaaaaaatta ttttgtcgcc ttcacttatg tgtggggatc tagcaaattt ggaaggaagc
     1081 atccaagaac tagaaagtat tgggatggat tccttgcata ttgacgtgat tgacggttct
     1141 tttagtccca gtatgccttt agggatcgaa acaatcaaaa gaattagaga aatcacttca
     1201 atgaattttg atgtacacat catggctaag gataacgata acgaattttt tattggagaa
     1261 atgttgaaaa ttggcgtaga gagcattact tttcattatg aaacaagcct ccatattgat
     1321 cgatatatcc agctcatcaa gaattctgga acaaaagtag ggatagcttt gaatccagca
     1381 actccgttaa atgtattaca atatatttta cccgagattg ataggatttg tttgatgctg
     1441 attaatccag gttttgcaac aaacaagtca gaaaaacaag tttcttacgc gctaaaaaaa
     1501 attacagatc tttgccagtt agtaaatgag aaagagttag cagtagatat ccaagtggat
     1561 ggacgggtat cgttagaaac gatcccggga ttattagatg caggcgcaac aaatctggta
     1621 ttaggaagta caagtttgtt tcttaaagga aatacattag cagaaaatca aaaactactt
     1681 tatcaagcga tgaagcaatc agttaggaaa aatcaataga tgtagtggtc ctgaataata
     1741 gaaatggagg ggaaatagtt gagttataag gcggcgaaac aaaatattgt aagagaaatt
     1801 actgaaacat tagaccgtat ttcttcaaaa gatgtggaac aattgataaa gaaaattgaa
     1861 aaagcggaac gagttttttt cgtgggggtt ggcagagtac tgttagcgct agaaggaatg
     1921 gcaaaacgct tagggcatct aggaattcag acagtagtcg taggacaaat cactgaaccg
     1981 gcaattacag ataaagattt attgattgtt ggttctggta gtggggaaag tgctttccca
     2041 ctaactattg caaaaaaagc aaaggaattt gggtcccaag ttgcccatat aggatcaaac
     2101 ccagacagca caatgaaaga atattcagat ctttttattc gtatacccgt acaaacaaaa
     2161 ttagcgttac cagaggaaat ttcttctata cagccaatga ctagcctgtt tgaacaaagt
     2221 gttcttttgt taggagatag tattgcttta gtgatgatag aagaaaaagc aattgatatg
     2281 tcaaagttgt ggcaatacca tgctaactta gagtaggtga aaaatgaaag cggtacattt
     2341 tggagcaggg aacatcggca gagggcttat tggacaaatt ctacatcaga atggattcga
     2401 tctatgtttt attgatacga atcctgaact gatccatcaa ttaaatcaag ataagggtta
     2461 tactatcgaa attattgatg aaatgaacag gagtgatttc attgatcatg ttgtggcact
     2521 gaatagttta tccgagctag aagaggtgat tacagcaaca aaaaatgcag atatcttaac
     2581 aacatctgtt ggcgcaataa atttagtaaa aattgcaccg atcattgcgc aagccttaag
     2641 taagcgattt gaacaaaagc atagcatcaa tatcgtagct aatgaaaatg tgataaatgc
     2701 aagtgatgtg ttgaaaaaag aaatttattc tttgctgtca gaaaaagaac aagagaattt
     2761 tgatgaatat gcatattttg tgaatacggc aatcgatcga caatctttag gaaaagttct
     2821 tggaggaaaa atgatctctg ttgtcgaacc ttattatgaa tggataatgg atcgacagca
     2881 gttagatcca actacatctt ttgatatgaa aaatgtaaat ttggttgatg atatggagcc
     2941 ttacattgag cgaaagcttt atatcgttaa tgctgctcat gcggcagtag cttatttagg
     3001 cgcactgaaa ggatataaga cgattcaaga agcaatccaa aatatggaga ttttcaatct
     3061 agtcaagcaa tttttaatgg agaatataga gtactttgta caaaaatatc atttttctag
     3121 agaagaatta acatcttttg tggaaaaaac attaaaccgt catgggaatc agaaactctc
     3181 cgatgaaatt actcgtgtag gaagttcccc tattcgaaaa ttaggcccta atgatcgttt
     3241 aattgctccc atagtaaaac tagattcata tcatttacct tacgatgcag gaataaaagt
     3301 aattgctgcg ggatatcatt atcggaatct tgctgatcca gaagctgaac aactacgtcg
     3361 aatgattgta aatgatgggt tgaaagcaac gattaaaaag atttctcgtt tggaaggtaa
     3421 gctgctgaat gaagttgtcg ctgcttatga gtcccagatt tagaggagga gaatatgcta
     3481 aaagaacaat tgtcaggaaa tacaatgttt atggatgcga tcgattcatg gcaagaggca
     3541 atccgagtaa gtgcgcgtcc tttgatagga aagggaataa tagaggaaag ctatgtacaa
     3601 gcgatgatac aaaatgtgtt ggataacgga aattatatta tattactgcc actagtagca
     3661 atgcctcatg cgcgtccaga atttgggagc aaaggggtcg ggatgagctt tttatgttta
     3721 gataagccag tcatgttccc aagtgaagaa ccagtaaaat tcttctttac cttttcttct
     3781 gattcgccaa agggacattt agacttaatg gccaatcttg gagaattgct gagtgatgaa
     3841 aaaatgtatc aaaaattatt cgatgtgaag acagaaaaag cattgttaga tttgataaag
     3901 aagtaaagga gagaagaaaa tggaggtagc aaacaaaaaa aaacgagtct ccatgcgagc
     3961 taaagttcaa gcgattggcg gtttcttaac aaatatggta ttgccaaata taggcgcatt
     4021 tattgcatgg ggaattgtta ctgcattatt cattccaact gggtggttcc caaatgaatc
     4081 tctgaatgaa ctcgtaagtc cgacagtcag ctatctattg ccgttactac ttgcctatac
     4141 tggtggtcgg atggttggtg gtacacgtgg agctgtttta ggtacaatcg gaacaatagg
     4201 tttgattatt ggtgctgaca taccaatgtt catgggagca atgattatgg ggccacttgg
     4261 tgggtggatg atgaaaaaaa cagatgattt tttagatggg aaagttcctg ctggttttga
     4321 aatggtcgtc aataattttt ctataggaat tattggtttc atactgatgt gcctttctta
     4381 tctggtagtt ggaccaataa tccaatcagc taatcaattt gtaacgagtg caattgaagc
     4441 attagtttca actggttttt taccgatact gtccttaatc aacgaaccgg caaaagtctt
     4501 atttttaaat aatgttattg accaaggtgt ttattatcca ttaggtatgc aacaaacatt
     4561 agaggcaggc agatcaattt atttcatggt agcatcaaat cctggccctg gcttaggact
     4621 attgttagct tattctttat ttggtaaaaa ggcagcaaaa cagacagcac caggtgcaat
     4681 catcatccat tttttcggcg gaatacatga gatttatttt ccatatgtat taatgaaacc
     4741 actcactata ttatctatga ttgctggtgg aatgacagga atcatcactt ttgaattatt
     4801 tgatgcgggc ctggtagcag gtccaagtcc aggttctatt ttttcttatt tagctctaac
     4861 gcctcgggga aattttttgg gtgtcatggc gggagtggtc acagcaacac tggtttcctt
     4921 ttttgtaaca tcagtaattt taaaagcaga taaatcaaca gatgaagaca gaaattttga
     4981 actatcagtt caaaaatcga aaacgatgaa atcagaagga agaaaattat taaaagaaga
     5041 aaatgctaga gaaatatgta ccgagaaaaa agagatgaat aaaatttcct ttgcttgtga
     5101 tgcaggaatg ggaagcagcg caatgggcgc aacaatattc aagaaaaaat tgcaaaaagc
     5161 aggtattact gatgttgaga taaaaaatta tcgaattgaa gaggtaccag aagatagtga
     5221 tttggtgatc gtacatcaag atttggagga acggactaga aaagcacatc ctaacatgaa
     5281 aattgtgaca ttaaagaatt atttgcaaga tccagtaatc aatggattag cagaagaaat
     5341 cattggatta aaaacagaag actaatttat gggaattttt gattaacctt tattaaaatt
     5401 attttgccta atataaaaag gttgtgacat ggcttgtgtc gcaacctttt tttgtcgcac
     5461 aaataattaa tcggatattt tatgtt
//
LOCUS       DAKCAA010000108         5458 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000108 DAKCAA010000000
VERSION     DAKCAA010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.111"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..1032
                     /locus_tag="OUE31_002591"
     CDS             <1..1032
                     /locus_tag="OUE31_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCU0223554.1"
                     /translation="LLGRDEVKLDIESIKDQITDKVILVTGAGGSIGSEICRQIIQFN
                     PAKLLLLGHGENSIYLIDRELRTHHQNCPTEIVPIIADIQDREKINEIMEQYHPDIVY
                     HAAAHKHVPLMEYNPKEAVKNNIFGTKNVAEAAKAARVKNFVMVSTDKANNPPNVMGS
                     TKRIAEMIVTGLNEESCTKFSAVRFGNVLGSRGSVIPVFREQIAQGGPVTVTDFRMTR
                     YFMTIPEASRLVIQSGALAKGGEIFILDMSEPVKIVDLAKNMIRLSGYSEDEIEIIET
                     GIRPGEKLYEELLLDKERNDEAVYEKIFVGNIKGYSMQTVMDFVKSLPQDDEQLAKEI
                     VTFANASNK"
     gene            1046..2266
                     /locus_tag="OUE31_002592"
     CDS             1046..2266
                     /locus_tag="OUE31_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HCU0223555.1"
                     /translation="MNKLEKRQIPFSPPDITEKEIEQVSEALRSGWITTGPKTKELER
                     EVADLCGVNRAVCLNSQTACAEMTLRLLGIKEGDEVITCAYTYTASASVVCHVGAKLI
                     LIDTQRDSLEMDYEQLENAITEKTKVIIPVDLGGVPCDYDRIFSIVERKKGLFHPVNK
                     IQESIGRVIVMADAAHAFGATWKEKPVGSIADFSNFSFHAVKNFTTAEGGAAVWKDIE
                     GIDNEEIYHQYQLLSLHGQSKDALAKTQLGAWEYDIIGPWFKCNMTDVVAGIGLAQMK
                     RYKGLLERRKEIIGKYDSAFKPIGIEVLNHYTENHQSSGHLYITRVPGITLEQRHEII
                     VKMAEVGVACNVHYKPLPMMTAYKNMGFDIKDYPNAYKRFENEITLPLHTKLTDEEVD
                     YVIKQFSRIVKEYI"
     gene            2327..2977
                     /locus_tag="OUE31_002593"
     CDS             2327..2977
                     /locus_tag="OUE31_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCU0223556.1"
                     /translation="MRTEEVRPYYDSLKKKKISLALKRGFDVFAASVMLVTFSPVLIT
                     ISIMIVRDSKGGVFYRQERVTQYGRKFKIFKFRTMVANADKIGTQVTVSNDSRVTKVG
                     EKLRKYRLDELPQLINIILGDMTLVGTRPESTHYVKKYTSEMYATLLLPAGVTSEASI
                     KYKDEAELLDKADDVDKVYVEKVLPEKMKYNLESIRKFSFINDIGTMIKTVFAVIR"
     gene            2987..3754
                     /locus_tag="OUE31_002594"
     CDS             2987..3754
                     /locus_tag="OUE31_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCU0223557.1"
                     /translation="MEKGLVSVIMPSWNTGNFIAESIQSVINQTYEKWELIIVDDCST
                     DNTDEVVGTFADKRIKYLKNEKNSGAALTRNRALREAKGEWIAFLDSDDLWKPKKLEH
                     QLKFMKKHNLIFSYHEYVKIDEDSQPLNIYVSGPPIVTKRKMYNYGYPGCLTFMYSAK
                     AMGLVQIKDIKKNNDYAILLKLCKKADCFLLKENLAEYRIRKKSISHDKLSKKLKSHY
                     DLFHMCDEKIAPVALWYACWNMFFGVMKKRKYEKIIK"
     gene            complement(4005..5324)
                     /locus_tag="OUE31_002595"
     CDS             complement(4005..5324)
                     /locus_tag="OUE31_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HCU0223558.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
BASE COUNT         1872 a          835 c         1167 g         1584 t
ORIGIN      
        1 ttactgggaa gagatgaggt aaagctggat attgaatcca taaaagatca gatcacagac
       61 aaagtcattc ttgtcaccgg cgcaggagga tcgatcggtt cagaaatctg tcggcaaatc
      121 attcaattca atcctgcaaa gctattgctt ttaggacatg gggagaactc gatctacttg
      181 attgaccgtg agttacgcac gcatcatcaa aattgtccta cagaaatcgt accgatcatc
      241 gcagatatcc aagatcgcga gaaaatcaat gagatcatgg aacaatatca tccagatata
      301 gtctaccatg cagctgctca taaacatgta ccactgatgg aatataatcc aaaagaagca
      361 gtcaaaaaca atattttcgg tacaaaaaat gtagcagaag cagctaaagc agcaagagtg
      421 aaaaacttcg tcatggtatc gacagataaa gctaacaatc ctccaaatgt catgggttca
      481 acaaaacgaa ttgctgaaat gatcgtgact gggttgaatg aagaaagctg tacgaaattc
      541 tcagctgtca gatttgggaa tgtccttggt tctcgtggta gtgtgatccc agtattcaga
      601 gaacaaattg ctcaaggagg gccagtcacc gtaacagact ttcgtatgac ccgatatttc
      661 atgacgattc ctgaagctag tcgtttagtt attcaatctg gtgcattagc aaaaggcggc
      721 gaaatcttta ttttagacat gagcgaacca gtgaaaatcg tagatctagc caaaaacatg
      781 atccgattga gcggatacag cgaagacgag atcgaaatca ttgaaacagg tatccgtcca
      841 ggggaaaaac tatatgaaga actattgtta gataaggaaa gaaacgatga agcagtttac
      901 gagaagatct ttgtgggaaa catcaaaggt tactccatgc aaacagtgat ggattttgtc
      961 aagagcctgc cgcaagacga cgaacaattg gctaaagaga tcgtcacttt tgcaaatgct
     1021 tcaaataagt aggaggaaaa tataaatgaa taaattagaa aaacgtcaga taccattttc
     1081 accgccagat ataacagaaa aagaaattga acaggtttca gaagcattaa gatccggatg
     1141 gattacaact gggcctaaga caaaagaatt agagcgagag gttgcagatt tatgtggagt
     1201 aaatcgtgct gtttgtctta attcacagac agcatgtgca gaaatgacct tgcgtttatt
     1261 aggaattaaa gagggcgatg aagtcattac atgtgcgtat acatatactg caagtgcgtc
     1321 tgtagtatgc catgtagggg caaaacttat tttaattgat acgcagagag attctcttga
     1381 aatggattat gagcagttgg agaatgcgat tactgaaaaa acaaaagtaa ttattccggt
     1441 agatctcggt ggagtaccat gtgattatga taggattttt tctattgtag aacgtaagaa
     1501 aggcttattc catccggtaa ataaaataca ggaaagcatc ggcagagtga ttgttatggc
     1561 ggatgcagca catgcttttg gtgcaacctg gaaagagaaa ccagttggaa gtattgcaga
     1621 tttttcaaat ttcagcttcc atgcagttaa gaattttaca actgcagaag gtggtgctgc
     1681 tgtttggaaa gatattgagg gaattgataa cgaagaaatt tatcatcagt atcagttgtt
     1741 atcacttcat ggtcagtcaa aagatgcact tgcgaaaacg cagcttggag catgggagta
     1801 tgacatcatt ggaccttggt ttaaatgtaa tatgactgat gttgtagctg gaatcggact
     1861 ggcacagatg aagagatata aaggcttgct tgaacgtcga aaagaaatta tagggaaata
     1921 tgattcagca tttaagccaa tcggaataga ggtattaaat cactatacgg aaaaccatca
     1981 gtcatctggt catttgtata taacaagagt tccgggaatt acgttggagc agaggcatga
     2041 gattattgtg aaaatggcag aagtgggtgt tgcctgcaat gtgcattata agccgttgcc
     2101 aatgatgact gcatacaaaa atatgggatt tgatattaaa gattatccta atgcatataa
     2161 gagatttgaa aatgagatta ctttaccgct tcacacaaaa cttacagatg aagaagtgga
     2221 ttatgtgatc aagcagttta gtagaattgt gaaagaatat atttaaatgt aatagcagaa
     2281 atgggagata caggtgttac gagaatggga gaaattacca aaatttatgc ggacggagga
     2341 agttcgtcca tattatgaca gtttaaaaaa gaaaaaaatt agtttggctt taaaaagagg
     2401 atttgatgta tttgctgcat ctgttatgct cgtaacattt tctcctgtat taattactat
     2461 ctcaattatg attgtaagag attctaaagg aggagtgttt tatcgtcagg agcgtgttac
     2521 acaatatggg agaaaattca agatatttaa attccgaaca atggttgcta atgctgataa
     2581 aattggcacc caagtcaccg tatccaatga cagtagagtt acaaaggtag gcgaaaaact
     2641 tcgtaaatat cgtttggatg aattgccgca gttaataaat attattttag gcgatatgac
     2701 gcttgtagga actagaccgg aaagtacgca ttatgtaaag aagtatacat cagaaatgta
     2761 tgctacgttg ttattaccgg cgggagttac atctgaggcg agtataaaat ataaagatga
     2821 agcagagtta ttggataaag cagatgatgt ggacaaagta tatgtagaaa aggttcttcc
     2881 ggagaagatg aaatacaatc ttgaaagtat taggaaattt agttttataa atgatatagg
     2941 aacaatgata aaaacagttt ttgcagtgat taggtaggga gtgtatatgg aaaaaggatt
     3001 agtatcagta ataatgccct cgtggaatac tggaaacttt atagctgaat caattcagtc
     3061 agtaatcaat cagacatatg aaaaatggga attaattata gtagatgatt gttctactga
     3121 taatacagat gaagttgtag gaacttttgc agataaaaga attaaatatt tgaagaatga
     3181 aaaaaatagt ggggcagctc ttacaaggaa tagagcatta agagaagcaa aaggtgaatg
     3241 gattgcattt ttagattctg atgatttatg gaaacctaaa aagttagaac atcaacttaa
     3301 atttatgaaa aaacataatc tgattttctc atatcatgaa tatgtaaaga ttgatgagga
     3361 ctcacagcca ttgaatatat atgtttctgg tcctccaatt gtaacgaagc gaaaaatgta
     3421 taactatgga tatccaggat gtctaacatt tatgtacagt gcaaaagcaa tgggattggt
     3481 tcagattaag gatattaaaa agaataatga ctatgcgatt ttattgaaat tgtgtaaaaa
     3541 agctgattgc tttctattaa aggaaaactt ggctgaatat agaataagaa aaaaatctat
     3601 atcacatgat aagttaagca aaaaactgaa aagccattac gacttattcc atatgtgtga
     3661 tgaaaagata gcgccagttg ctttatggta tgcgtgttgg aatatgtttt ttggagttat
     3721 gaaaaaaaga aagtatgaaa aaattattaa ataacgaaga tgaggagaag aaaaatgtca
     3781 ctttatgaaa aaataattaa tcctgaataa ttcatagctt taattctttg gcacatttta
     3841 ttgaaatatg tatcactaat atccctatca actgattttg actaaaaagt tacttcaaac
     3901 attcactgtt caaaaatatt gaggaataaa ttttgggtgt aaggcatttt gagcatactt
     3961 ctccctggat aacttcccag taaaaaaatc gttagattgt tggattagat ccattgactg
     4021 gctcgcctca ggcgagcaaa gaccctgtag aattcattct gatacacatg ataactagat
     4081 aatttgagat agactcgtct acccgtttgg actaatttcc cagcaacttt cagaaacttc
     4141 aatcgaatag aatgaatggt cattcccttt tggacttctt caaagccaat cgttcttaag
     4201 aagttgacta agttgtaagc tatcaagctg agcatcattc ggacatgatt ctccaaaaag
     4261 cgaggactgt ctgttttgtc aaagtaaaag ccagctttcg cttctttaat gaagttctcc
     4321 attgtgccac gtttggcata gatagaaaag atggtatcag gagaaacatt ttctgataga
     4381 ttcgtcacga taaattcatg tcgaaagagt agttcgcccg cttcacgtgt tgagcgtata
     4441 cacacgcgac gactttgtga ccaggattgt gcttgataag tggtcgagaa gtactgaact
     4501 tctcgttctt cccacttttg attatcgcca taaagtactg atttctcagc tatttgacct
     4561 agtctacgat tattcttcag tcgaataaca taatgactct tttttgattc acacgaatca
     4621 tacacaccag gtgtagcgaa cccgctgtct ccacgaacca agatgtcagt gtttggtaga
     4681 gagtgattat agtgctctaa taaaggtgtg agaaactcct ttacgccttt tgatgtatat
     4741 tgatttcctg aacgtagttc agcttttaag aagtcaccag tcaatccgtc aaaagctacc
     4801 aatggatggt aaccataggt ttggtagtgt gtattataat tcgtttgttc ttggtgacca
     4861 aatgtatctg aatgggtcga atctaaatca atgattaatt ccgtatcatt acggatgagg
     4921 cgtgctttat cgataagttc ttggttcaaa gcttgaagtt catggatatt ctcctcagat
     4981 agtcgatcta aaaatcggga aagtgaagat tgagaagcga gttctttcct atctaaaaca
     5041 gctttaaaca caggatcttg tctcaggaga ttagctgcag aatcagctga gtaaccagca
     5101 attaattgca taatgaactg ctcaagtatg gataagttgt catgagtaaa atacgctcgt
     5161 tcgtcttcaa tgtgaatgtg ttgcttagcc agttcagaaa aaccaaagat gttcatcagc
     5221 tctttcacta ggacgagacc cgaatcactc gataattgac cacctgtatg agaaatagtg
     5281 atatttgaat tgaattttac ttggtttttg tgtaagctag tcatgaaaag aactcctttc
     5341 ttttggttgg tttagtcact ttaaccatag cagaaagggg ttcttttttc atcacttaac
     5401 gggtgaagat gaaaaagtaa ttgtaagctg ccgtgaggca gtttcacatg gttttaat
//
LOCUS       DAKCAA010000109         5339 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000109 DAKCAA010000000
VERSION     DAKCAA010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.112"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(62..280)
                     /locus_tag="OUE31_002596"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="OUE31_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(546..740)
                     /locus_tag="OUE31_002597"
     CDS             complement(546..740)
                     /locus_tag="OUE31_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223559.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(840..926)
                     /locus_tag="OUE31_002598"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="OUE31_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="OUE31_002599"
     CDS             2092..3132
                     /locus_tag="OUE31_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCU0223560.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3956..4288
                     /locus_tag="OUE31_002600"
     CDS             3956..4288
                     /locus_tag="OUE31_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HCU0223561.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="OUE31_002601"
     CDS             4907..5248
                     /locus_tag="OUE31_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HCU0223562.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1942 a          728 c          900 g         1769 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttt tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattaa
     4861 tataaagcat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa ggggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgacgat taataaaaag gtagtattac cttaggcatt gagtaagga
//
LOCUS       DAKCAA010000110         5094 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000110 DAKCAA010000000
VERSION     DAKCAA010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.113"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(134..718)
                     /locus_tag="OUE31_002602"
     CDS             complement(134..718)
                     /locus_tag="OUE31_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCU0223563.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            complement(929..1132)
                     /locus_tag="OUE31_002603"
     CDS             complement(929..1132)
                     /locus_tag="OUE31_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223564.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            complement(1142..1564)
                     /locus_tag="OUE31_002604"
     CDS             complement(1142..1564)
                     /locus_tag="OUE31_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223565.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRDGIAIGNPTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1802..2416
                     /locus_tag="OUE31_002605"
     CDS             1802..2416
                     /locus_tag="OUE31_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCU0223566.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(2581..3405)
                     /locus_tag="OUE31_002606"
     CDS             complement(2581..3405)
                     /locus_tag="OUE31_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223567.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(3429..3584)
                     /locus_tag="OUE31_002607"
     CDS             complement(3429..3584)
                     /locus_tag="OUE31_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223568.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFILKKN"
     gene            complement(4043..4300)
                     /locus_tag="OUE31_002608"
     CDS             complement(4043..4300)
                     /locus_tag="OUE31_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCU0223569.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(4293..4562)
                     /locus_tag="OUE31_002609"
     CDS             complement(4293..4562)
                     /locus_tag="OUE31_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCU0223570.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(4693..4872)
                     /locus_tag="OUE31_002610"
     CDS             complement(4693..4872)
                     /locus_tag="OUE31_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223571.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
BASE COUNT         1677 a          908 c          694 g         1815 t
ORIGIN      
        1 ttaatattaa caaatgaata aaatccttac aacatttgag aataagttat cagtagacac
       61 ttacaaaaaa ttctcatact attgtcactt ttctagataa atggcaaaaa ttttcagcat
      121 taaatgacaa aaactaatga gaatttgtct ttccattttt ctcctccatt tttgccaaat
      181 aacgataaat ggtggttctt gagacgttcc accgttccgc aatagtctta ataggtgtac
      241 cgctatccac taaagtcttc agtaattcca aatcttgttc agacaatttt tcaggacgac
      301 caccaaaccg tcctcttgca cgagcagctg ctcgtcctgc tgcggatcgt tccaggatca
      361 aattacgctc aaattctgca aatgccgcaa acaaatgaaa catgagctgt cctgtagaac
      421 ttgatttgtc catcgtaata ttttcttgaa tactatgaaa actcacacca cgctcattca
      481 gtcgattgac gattgaaatc aaatcttcca tatttctacc taaacgatct aagcgccaaa
      541 cgacaagtgt atcgccagag cgaacaaaat caatggccat ttctaatcct ggtcgattac
      601 tttttgcccc actcatatga tcagtaaaaa ttttttcaca accaaattta tttaggctgt
      661 cttcttgtaa atccaaattt tgtaaaccag tagatacccg ggcgtatcct attttcaaaa
      721 aaatcactcc ttcattaatt ttattgtaac ataactttat ccatatagtt taactgaaca
      781 tagatattgt tatgggttta tgaacatgaa atgaattgtt tttttgaaaa ataaagcaaa
      841 aaaagaaagt gtccagaaat gggtgatttt atgaacactt tcaattagaa aaaaagaatg
      901 tcgactagac actctttttt taaaatcatt atttttcttt ttgatatgtt ttttggtctc
      961 ttttttttct tttttcttca gaatcttcta gattagaaat tgatttttga attttttgtg
     1021 tctcctgtaa agttcgctga acttgtaaag ctgattcttc tttcggtaaa ttaattttac
     1081 ttagaatatc gctatcttga taaaaatttg gtgtgttcac aaattctggc ataaaaaatc
     1141 cctactttct agttaaggtt cctgaataag tcgcaatcca attgtttcca gctgatttat
     1201 aactttgtaa atacaatttt ccatagtacc aataaccatt tcttttttct ttccaattcc
     1261 gtgattgagg aggtctagaa ggccaaccaa ctttatcaaa aatcatcgtt cctgtcactc
     1321 gtatcgtttt agaagctgct agagcaagta atggagaaac tattaaataa ttttcagtaa
     1381 cagttaagtc gttagttggg ttaccaatgg ctattccgtc cctatctaaa ggagttaatt
     1441 cttggttatt atctactaca gtagttggtt catttgtact atcagcaaat gtaggaattg
     1501 tagttccagt tacactaatt ccaatagtta aaatacctaa agataaaata aacttatttt
     1561 tcattgtcta tcacctcgaa atcaaaacta agaaaacgtt ttcttaataa atcttaacag
     1621 ataaatcaag ttatatacta gaaaattcat aaaatatatt tttaatgtca taatcgttta
     1681 aattttcttg attgacattt atttacaaaa aatattgcca tttaaaaaga aaagtgacat
     1741 atggcttcct cgtgtatgat tagggtgtat tttaaatagt tgcagaaagt aggtaaaagt
     1801 tttgagagtt gcatacatac gtgtctcatc gatcgatcaa aatgaacaac gccagattga
     1861 agaaatgaaa aaattcggtg cagagagaat tttcatcgag aaacaatctg gcgcaacgat
     1921 tactcatcga cctgttttcc aagaagcatt agattacgtc cgagatcaag atatttttat
     1981 tgtggaagct attgatcgac ttggaagaaa ttatgacgag atcatcgctt cagtcaatta
     2041 cttgaagaag aaaaatgtga agctgatcat tactagttta ccgatcatgg ctgaagcaat
     2101 tggcaatcct ctcctggata aattcattaa ggatctgatc atccaaattt tggccatgat
     2161 cgctgaacaa gaacggactg aatcgaaacg tcgccaggca caaggaatta agatcgcaaa
     2221 agcaaacggc gtctacaaag ggcggcccaa attatacagt gcagacgcaa aagatcccca
     2281 acgtcgcctt gtttacaaaa gcatcgttga agatcttaaa aatggtgttg cgattgctaa
     2341 gattgctaaa gactacaatg ttacgagaca aaccgtgtat agaataaaaa aagacagcat
     2401 ggtcaatgac aaatagttga tcatgctgct tttattatct tctcatcttt aatttcctac
     2461 atataattac tatctataaa attaagtctt actcagaaca gataaagcat aaaattccaa
     2521 caaaccattt tttacttaac taaataaaga gtctgttaat ataatcttca cttatttacg
     2581 ttaatcccct actgtatttg ttggttcctt atctatattt tctacaaaat ccttattatc
     2641 ttgtgattta gcttcgtata attctttgta tgtcgacaca ttggttatac taattcctat
     2701 agctagttct tgagactcta cttttctctc tagctccttt gacaaagtga tttgagattt
     2761 atttggttcc gttggagtca attctataga ttcttcataa aaatctctat acataaagct
     2821 atcattaatt ttataaaaaa aattaaatgt ttttagcact gccatataac attcaaaaca
     2881 ttcttctata gttggtttac ttccttgagg agaatgaacc aatttattac gtttttctat
     2941 gaaattttta atttcctttc ttatttcttt cggaaactca atattaaagt accctttaaa
     3001 catgctccct aataatttgt ctacaggggg agattgtaaa ttctcaaata ttagagttaa
     3061 atcaggtttc tcttgttgat aaaattcctt tacccctatt tcacaggctg taattatcga
     3121 aataaaccta tctctagtat ttgatatatt tttacttctt ttaaggagta taagagaaaa
     3181 ggggatactt tcgtgtccat gcatgtaatt aactaattgt tgagcttcag aagttatatc
     3241 tctaattata tagttaacgg aattaggaag tgtctttaac tctaatgaaa tttctatcca
     3301 attactatct tctaatctgt atatgctcga agtataattt gattcgtcag caagcatcgc
     3361 tacatcccaa acactgatca taaaatcttt taaacgttca atcatttcag caatattgct
     3421 aaaatcagct aatttttctt tagaataaaa aaaacattta tatcagaatc aataaattct
     3481 atttttttta ttactatatc gtcatcatta tcttgaccat ttatgtttat tgttccctga
     3541 gtggggagta cttctttcaa attcaagtta aatttatatt ccattacttc tcctccaata
     3601 tataaaaatt acttaactgt atccaaattt aatatgtaaa taaatcatta atttttagct
     3661 aaattctatg agaagtttat ttttgttgtt tttgctaatt aactaaaact agtacaaaaa
     3721 atttaaaata gattattaaa cctattgctt attctattca gtcatatata taagcgtcat
     3781 cctttagtaa ctaacatccc acactacaat agtattataa catatctatt caacttcaaa
     3841 ttgttgaaat ttaagccatt tatatttact tttcctcaac tttagaaatg attttactaa
     3901 ccttatatcc gtaatacgcg taacaaacac attcattaat aacaatcaac actaagctat
     3961 attagctttt taaatgacta gggtaaataa aataaggatc aaaaactttt aagtttctga
     4021 ccctttcctt acttccgatt ggttaatagt gatcttttgc agaataaata aatatcgttt
     4081 cattttcaac tctatatatc agtctatgtt catctgtaat tcttctggac cattttccag
     4141 ataaatcatg ctttaatggc tcaggttttc ctaatccagc aaagggggaa cgatcgatat
     4201 cttttattaa cttgttaatc ttttttatat tgcttttgtt tccttgctca tgccaataaa
     4261 gataatcatc ccaagcatca tcagaccaag ccttaatcat cagattcaac ctcgattaag
     4321 tcatgtgttt taaatgcacc tttggagaat tgttcatctc ctcgacgaat tttttccatg
     4381 acgtaattat tagaaagtgt tctcaacgtt tcttgcatag aatcataatc tctttttgat
     4441 aatacaacaa ctgtatcttc tacatcttta cttgttacaa taagtgtttc agcatcctca
     4501 ttaacttgtt tcatataact acgtaaattt tggcggaaat ttgaataagc tactgcttcc
     4561 attcctttca ccccttattt atttctataa aacaattgta cattatattg tacaattaag
     4621 caaatgatta atattctaac ttcttataat taaaagtgct atcactttta gtttttagga
     4681 taaaaagtga cgtcactttt tgagtgctgg tacctcaaat cctgcttttt cttgggcaat
     4741 caataaatct aacgcaatac acataatcct ggattcactt ttgccgtact tctgctttag
     4801 ttgctgcaat tctttttgtc tcttttcatc caacgtcacg ggtaaccgtt tatttcctat
     4861 tgcaattggc attagtactc tctcctttca tcgaaataac cctattaaaa atatggctgc
     4921 aatcaacttg aatattagac tcacaagggt taacacaaag cgccaaaaga tcaaacaaaa
     4981 taccagtatt cctaagaata ctacgaagtt taaatgtaga gctgcaccat gacgcataag
     5041 tatctcgcca acaaacagta cgaacaatag aggaatgatt ttattcatat ggat
//
LOCUS       DAKCAA010000111         4980 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000111 DAKCAA010000000
VERSION     DAKCAA010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.114"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            110..889
                     /locus_tag="OUE31_002611"
     CDS             110..889
                     /locus_tag="OUE31_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223572.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRITYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEKIRNEKISVAYATKAQTVAEQMGYSNISY"
     gene            935..1879
                     /locus_tag="OUE31_002612"
     CDS             935..1879
                     /locus_tag="OUE31_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCU0223573.1"
                     /translation="MARRRRKSRGKKIFLIILAVLVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            1895..2674
                     /locus_tag="OUE31_002613"
     CDS             1895..2674
                     /locus_tag="OUE31_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HCU0223574.1"
                     /translation="MEETISLKEIFETLRKHLATIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNDKTAPSRRSRSRV"
     gene            2686..3384
                     /locus_tag="OUE31_002614"
     CDS             2686..3384
                     /locus_tag="OUE31_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HCU0223575.1"
                     /translation="MARTQKQKATQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPREGKSTTSANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVVDVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3412..4176
                     /locus_tag="OUE31_002615"
     CDS             3412..4176
                     /locus_tag="OUE31_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HCU0223576.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTMEVPLYAEQLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYKQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPIYEEVKKKKFGLF"
     gene            4189..>4980
                     /locus_tag="OUE31_002616"
     CDS             4189..>4980
                     /locus_tag="OUE31_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCU0223577.1"
                     /translation="MFVLTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFGSLSASAVSSIIILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYVETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLL"
BASE COUNT         1724 a          910 c         1037 g         1309 t
ORIGIN      
        1 ttctgtgaat atattagttt aattatgttt tttaaaataa aaagttgtca tttttatgta
       61 agtgaattat atcttaattt atctatcatc aatacttagg agtgaatcta tggaaaagcc
      121 attcgtcaag tcattgactg ctgtggcggt aggtgcaggt gctattgcga tctgtttgtt
      181 tggataccat atcaataatc agcggcaaca tcagcaacgg atcacttatg cagaatctgc
      241 catcaccaat caaaaagata ccttgacttc tttatcaaaa gaagtagaca agttgtatag
      301 tacaaaagaa aaaatttttc taaaccctga aataacagaa gaaacaatca caagtttgtc
      361 caataagcta tcctctgtca aactttcagc agatgattac gacatcaaag aatcagaatt
      421 gcctaaagaa gctgttgcaa tccaagatga gaagaaagca atcgtgacac agttagatag
      481 tgcagaatca aaactgaaga tccagacagc tgtcaacgat ttatttacta aaaatgtatc
      541 aaactggcag caagctgtag acgatgtcat catcaaagaa aaggtgacca gtgcagatgt
      601 cgctcgtgta cgtgaaaata tgagcttttt taaagatagt ccttggaaaa cggttgttat
      661 gcaatatcta ggattcgctg atactcagat cgcgcaagtc acgcaactag atcagttatt
      721 cgatacgatg ttaaaggatg gtcaagtgac tgccaccgct acttacgatc aatatttgac
      781 ggcgctcagt caaatagaga agatccggaa tgaaaaaata agcgtagcat acgcaacaaa
      841 agcacaaact gttgctgagc aaatgggcta tagcaatata agctattgac agttaaaacg
      901 ttgattcaag caaggttagc aaacggagga aactatggca agacgaagaa gaaaatcaag
      961 agggaaaaaa atatttctga ttattttagc agttcttgtc gtattagtat tagcaattgt
     1021 aggagtagga gcaaaattat atctggatct ctcacattct attgagaaaa cttacgaatc
     1081 agtggaacga acccaaggag aacgaacgaa accagttgat ctggacaaac aagaatcttt
     1141 ctctgttcta ttgatgggga ttgatactgg agatttaggt cgggtcgatc aaggaagatc
     1201 agatacgatg atggttgcca cagtcagtcc tgaagacaaa cagacaacga tcgtcagcat
     1261 tcctcgagat acgtatgtcg acatcgtagg tcgtgacaca aaagacaaga tcaaccacgc
     1321 ttacgcattc ggcggagctg ccatggcgat ggataccgta caaaaatatg tagacatccc
     1381 aatcgatcac tatgtctcta tcaatatgaa agggctaaag gaactcgttg atgcagttgg
     1441 tggtatcgaa gtcaataatg acctcacttt ctcacaagat ggctatgact ttacaatcgg
     1501 taaaatcaca ttgaacgggg atcaggcatt atcttattct cgtatgcgtt atgaagatcc
     1561 caatggtgac tatggtagac aagagcgtca aagaaagatc gtagaaggcg tagcaaaaaa
     1621 agtattgagt ctaaatggtg tcagcaacta tcaatccgtt ttgaatgctc tagagtcgaa
     1681 tatgaaaaca gacatgagct ttgatgaaat gaaaaaaatc gctttagatt atcgggaggc
     1741 atttggtacg atcaagcaag atcagctgca aggagaaggc ttcatgcaag ataatatctc
     1801 ctatcaaaaa gtcagtgatc aagaacttga tcgtgtgaaa aaagaattaa aagatcaaat
     1861 gaatctagag aataaatagg aaagtggaga aaaaatggaa gagacaatca gcttgaaaga
     1921 aatttttgaa acattacgca aacacttggc aacaatcatc atctcaatgt ttgctggctt
     1981 ggccatctca ggaatcgtaa catttttcat cttgacacca aaatacagtt cacaagcaca
     2041 attgatcgtg acactgccac aatcagacac agcaaatgtc aatgatgtca atacgaacct
     2101 gcaaatgatc aatacgtata aagatatgat cgtcagtgat ttagtactaa atgaagtcaa
     2161 agatcgttta gaaacagaag acaatgtgaa aatgactgct ggacaaatca aagatgcgat
     2221 ctccgtcaat cagtcacaaa attcacaaat gttctcgatc caggcaataa gcacgaatgc
     2281 agtgactgct caacagatcg ctaatacaac ttcacaagtt ttccaagaga acgcaaaaga
     2341 cgtgatgaat gtcgataaaa tctcgattat ttcaggtgca gttgccaata cgacacctgt
     2401 ttcgccaaat aataaattga atctagtgat tggcttagtg ttaggaatga tggtaggcgt
     2461 aggtctggca ttcttattcg aattacttga tcggacagtg aaagatgaaa aatatgtgac
     2521 ggatacatta ggattcccaa tcttaggaac agttccagaa atgtcagcga aagaattgaa
     2581 tgctggtatc cgtaaaaaag gatcagctcc tgcacgacca aaagctacaa acgataaaac
     2641 agccccatca cgcagaagcc gctcaagagt ctaggaggaa aaaaaatggc acgaacacag
     2701 aaacaaaaag caacacaaac tcatgcagtc agtttgatca cattaacaaa cccatcttcc
     2761 ccaatcgccg aacaatatcg tacgatccgg acgaatatcc agtttgcctc cgcagctggt
     2821 cagcaaatca aaacgattgt cgtgacttca tcaggtccta gagaagggaa atccaccact
     2881 tcagcaaaca ttgcagtcgt ttttgctaaa tcaggtcaac gagttctatt agtcgatgca
     2941 gatttacgta aacccgtcgt ctataagaca ttccagctga acaatgccag tggattaagt
     3001 acagcactta gttcatcagg aagtgtagta gatgtaatcc aacgaacgcc agtcgagaac
     3061 ttgtcgattt tgcctagtgg gcctaagcca cccaacccat cagaattgtt aagctcgcca
     3121 agaatggatc agattctagc cgaagcaaga cagttatttg atgtggtgat attcgatatg
     3181 ccaccagtag tagccgtaac agatgcacag atcatgtctt caaaaacgga tggcacttta
     3241 ttggtcgtac gtgaaaatac atcacgtaaa gaatccttga ctaaagcaaa agaactgcta
     3301 gagatggtac aagcacgagt cttaggtgtc gtatataacg gagcagaaca cagcaaagat
     3361 gctggttatt attacggaaa ttaagaaata agaagagagg agacaagaga aatgatcgat
     3421 ctacattgcc atatcctacc aggaatcgat gacggggcag aaaacttaga agcaagtatt
     3481 gcaatggctg aaaaagcgat tcagcaaggc atcacgcata ttttatgcac acctcaccac
     3541 aataatggaa aatacagcaa tgaaaaatca caagtcattt ctctagtcgc ttcgttacaa
     3601 gccgaattag agaaaagaca gttacctttg acgttattgg aaggacaaga agtacgtatt
     3661 accggaacgc tcatcgaaga catccatcga gatgaaattt tatttacaga tttagatgat
     3721 acatatcttc tgatcgaatt tccgacaatg gaagtgccgt tatatgcaga acagcttttt
     3781 tttgagttgt tagaactagg aaagacacca gtgatcgtcc atccagaacg caacgcgcat
     3841 tttcgagaag acccaaatca tttgcttccg ttcctagata tgggatgttt ggcccaactc
     3901 actgcgccaa gttatgttgg ggtatttggc aaagacatcc agaaaacagc caaaacgatg
     3961 gtcaaacata atctcgtgca gatggctgct tctgatgctc atggggtctc taagcgcacc
     4021 ttttacttaa aagagtgcta taagcagatt gccaaggact ttggtaagga aaaagtagta
     4081 cagatgaaac aagtcgcaaa ggatctgatc aacggggatg aaatcagtta tccaatctat
     4141 gaagaggtaa aaaagaagaa gtttggttta ttttaggggg aatgtagggt gtttgtatta
     4201 acaagaagaa gaaaaattgc cacattggta tttgtggaca gcttgttgtt gattgctgcg
     4261 aatattgcag cagctaaatt catgaagccg tttgtagcta taccaatgga ccttatttta
     4321 atctctatcg gtttgtcgat tggtttttat ttattctatg gtagtttatt caaagtattc
     4381 actcggatca atcgctatac aaatttaaga gaaatcattg cgatttttgg ctcactatct
     4441 gcaagtgctg tctcaagtat catcatattg ctgttcataa atcggcgata cagtttacga
     4501 ttagtcattt ttgcttacct gctttcgcta ttattgatta ttggtagccg attgatctgg
     4561 cgtatctatg tcgaaacaaa aaatatgaga tatgtatcag cagattctgc taaaaatacc
     4621 ttgatcgttg gtgctggcga aggtgggcgt attttataca acagctttct tggatccaaa
     4681 acggctcaag atatccacgt tgtcgggttt gtagatgatg atccgaataa aagaaatacg
     4741 tatctttcag gaaaaaaagt attaggtgca ttaaaagata ttccggaatt gattgaaaaa
     4801 tatgacattc aaatggtaac gattgctatc ccttccttat caagaaaaaa attacgaaga
     4861 atcttcgagt tagtcgaatc cgctcgtgtg aaagtcaaca cgatgccttc tatagaagaa
     4921 cttgcttcag gaaaaattag cgtatcaaaa ttaaaaacaa ttgacgtagt ggatttactg
//
LOCUS       DAKCAA010000112         4772 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000112 DAKCAA010000000
VERSION     DAKCAA010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.115"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..1216)
                     /locus_tag="OUE31_002617"
     CDS             complement(<1..1216)
                     /locus_tag="OUE31_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223578.1"
                     /translation="MQTFLTKTSFKKVVLLDYLLEKDNWCAMEELRNLLNVTEKSVLH
                     YIEELEDLFKQYNGNILLKNEDNKRFFIKKEKDFPIYNIYLHFYKASYNYHLIDFMYK
                     YPRSVLKDFAKEQFTSVSTVFRYAKLLIPYFRRYHITFHPFQLELNASEANIRSFFYY
                     FYWNSTRESSDKWPFHIEQKEIEKYIVAFEGIYDITLTIFQKRVFSFWLAINIERSSF
                     RKVRVDNEYKSVISDDPHFNLLKKWSKQINLSFNSDELCFLYRIIYSFGVIDGNAIYE
                     NSHAYAHQRQNTCSYRAVENLEKVLQSMFRFSLDIKDPELIFNFIAFHERSYLFYGNP
                     DLFFNRSYIEEMKEEEPRTYHIMEKLKKELQANADLDVSKKLENWAQLFLDYYYVLDY
                     YDLFLTNVKPIKI"
     gene            complement(1997..2350)
                     /locus_tag="OUE31_002618"
     CDS             complement(1997..2350)
                     /locus_tag="OUE31_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223579.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
     gene            complement(2982..4607)
                     /locus_tag="OUE31_002619"
     CDS             complement(2982..4607)
                     /locus_tag="OUE31_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCU0223580.1"
                     /translation="MKKIYSKEIDCFRGIAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
BASE COUNT         1637 a          803 c          593 g         1739 t
ORIGIN      
        1 aaatcttaat cggtttaaca tttgttaaaa ataaatcata ataatctaac acataataat
       61 aatccaaaaa taattgtgcc cagttttcta atttctttga tacatccaaa tccgcatttg
      121 cttgtaattc ttttttgagt ttttccatta tgtgataagt tcgaggttct tcttctttca
      181 tttcttcgat atacgaacga ttaaaaaaaa gatctggatt accataaaat agataacttc
      241 tttcatgaaa tgcaataaaa ttgaatatga gttctggatc ctttatatct aaagaaaaac
      301 ggaacatgct ttgtaaaact ttctccaaat tctcaactgc tcgataagaa caagtatttt
      361 gtcgctgatg tgcatatgca tgactatttt catatattgc atttccatca attactccaa
      421 aagaataaat tattcgataa aggaaacaca gttcatcgct gttaaaagaa agattgattt
      481 gttttgacca cttcttcaaa agattaaaat gcggatcatc tgagataact gatttatatt
      541 cattatctac tcgtactttt ctaaatgaac ttctttctat attaatggct aaccaaaaag
      601 aaaatacacg tttttgaaaa atagttaacg taatatcata aatcccctca aaagcaacta
      661 tatacttctc tatttccttt tgttcgatat gaaatggcca cttatcacta ctttcacgtg
      721 tagaattcca atagaaataa taaaaaaagc tacgaatgtt tgcctctgat gcattcaatt
      781 ctaactgaaa tggatgaaat gttatatgat aacgcctaaa atatggaatt aagagcttcg
      841 catatctgaa aacagtagat acactagtaa attgctcttt agcaaaatct tttagaacac
      901 ttctaggata tttatacata aaatcaatca aatgataatt ataagaagct ttataaaaat
      961 gaagataaat attataaata ggaaaatctt tctctttttt tatgaaaaat cgtttattat
     1021 cttcattttt cagaaggata ttaccattat attgcttaaa taaatcctct agttcttcta
     1081 tatagtgtaa gactgacttc tccgtaacat taagtaaatt tctaagttct tccattgcac
     1141 accaattgtc tttttctaac aaataatcta ataaaactac ttttttgaaa gatgttttag
     1201 ttaaaaaagt ttgcatcatt tcacctcaat aagttacttt tgtttatttt aatcaaagaa
     1261 taaacttctc tcgttcgact ataactgatc gaacaaaaga agccttttaa taaatataat
     1321 ctcacttaca tacataggct agttatttgc ttctagctta tgataagtat ataaacggat
     1381 atcgatttca taattgtttt atcttaaaca tcatagctgt aattgttttt atttttacat
     1441 gaagaattat tataatctag tttaattttt ttctgaaata tagaataaaa ataaaaacat
     1501 cttttcattt tgagttatta atggagatgt aaatgattaa caatatgtaa tttaattttt
     1561 tattcctgca ttaagataat ttgattggta aataaaaaca aacgtaaatt cgttatttta
     1621 attcctattt attgtgaaca tatccaattt ttatcacata gatatttgta taaacatttt
     1681 atgaatgcgc ttgtatttaa tttagaaagt gttactatct atttaggcaa atttttgcta
     1741 atattttgtt ttttcattta ccatctgtag aaatcattta atgatttcta tcttctcctt
     1801 ccaacttttc tgatgatgca tcatgaatta acagtgcatt atccatcttt tccatgttaa
     1861 aagaactaag aatcaagata acgtcttgat tcttagttct tttattcctt ctagaaaata
     1921 attgttagca atatagttta tatttgtaaa tactaaatca gtagcttcta gttgctttcc
     1981 tgcttaatag ttcatattac tcaatgtaaa aaataattga ttgtggacat tgctcatcca
     2041 ctttgtatcc acaactttct ttataatagg tatgataatc actctctacc atattaatta
     2101 actcttttcc cccgcaaaat tcttcaatgt ctaaattaat aaattcctct aaaagggaaa
     2161 gcttagagtc aatcgaaagc attttaggta acatagtcca aaagtcatta tcatcgtttt
     2221 tacgtagtgt ataatatgtt tgcttttcta gatttaatac ataattatat gcatcataat
     2281 ctcccttttt ttcaaaaaaa tttttcatat ttaaaaatct actcacaaat tttttcttga
     2341 aactattcat tttctcacct ctatttattc tttttcttgt ccatagcata acttttgaat
     2401 agagtaacta aattcaaaag ctattatagt ataaaaatac actttttgtt gttcaaattt
     2461 ttcatctaat tgtgcagtaa ttttgaactc tatatttttt aatatttaat gcttaagcaa
     2521 tcatttataa aaaaagactg gacgataatt aaaataacaa aaaaggctgt gacacgtctt
     2581 ttgtcacagt cccttctagc attatattac tattatttat tcactgcatc ttcttaagag
     2641 taaaacatac ttgatcgttt gtttctttac taacagcctt ctttacttgg ttcctacgat
     2701 ccttaatttt atctaagctg attgctgctt gtaaccataa aacttcgatc agaacataca
     2761 tcctagtatt gtcgtctcgc tcatgttctg tataacaaag aggataaatc caaagcgatt
     2821 tctttccaag aagctctcag ttaacgacct cgcccatctc ttttttacca cgaatattaa
     2881 aaagctcctc ctcttaaaca ccgtttatca tatgaagtat tttttattta aattgattca
     2941 cctattagga aaaagtaagg ttaacacacg taatcactac cttattgaat aactgaagca
     3001 atatactttg cataagctgt acgtccactt tcattcaaat gggtttcatc atcataaaaa
     3061 aattcaggat gatttttgct ctcactatac caatcgatca tcgttatatt agaatactga
     3121 tttggcaatg tagctaatgt ggcatttatc gtatcttgcc agccagttgg tgcttttata
     3181 tttacccagt atactttttt atctttcagc aaagacattg tttgttctat agcttcatct
     3241 gttatcacac cattggttcc taacccgatc actatttgtt ggtaagaaac taaatcttta
     3301 tgctccttta agatttctgg taacgcagtg atttgtcttg attcttttgc atctaccaat
     3361 gcttcttttt taaatgtctc ctttagttcc tgatacgccc ccagcataac agaatcaccg
     3421 ataaataata ttttcttctc ttgtgacaac agattttctc ctgcatttgc tttactagag
     3481 ttttctttta ataaactttg caactgattt tggtcagcgg tcagtcgact ggcaggagca
     3541 cgtaatacca gtacagaaac tccgattatc attagtgcca tagctgtcca aattttgggt
     3601 gatctcatct tttgcactcc ttttctaaag caagtaatca tgagtaatgt acataaaaac
     3661 acagtgaata gacctgcgat atccaaatat ttccaatggt gatgtttgaa tagatttgtc
     3721 agagcaatca atactgggaa atgcaccaaa taaagttcat aactgatttt tcctacaaaa
     3781 gaaagttttg tactagcgat tttggtcttt tttgcaatgt tcatatcatc gacactggct
     3841 aacaatagag caaaacaaat actgatcagt agttcattta gtgtataagg aaaaatcggg
     3901 aacagaatca gacaaagact agctagtaat aaaagccaga ttttactaaa agtgttttgt
     3961 tcaaagaaac ggccaatagt tattcgatta aaataccccc aaactcctaa taaaaatgga
     4021 aaaagtttag ctatcgtatg ataatatgcc ttagttgaag gtaaaaacaa actaaaaaga
     4081 atagaaacaa aaatcaatgt atagattaag taaaacactt gttttcttct catacgctta
     4141 atgacaataa acaaaaatgg ccatatcaaa tagaattgta gttcaactga aagcgaccaa
     4201 taatgtttaa ataaagaagc attaaagtaa gagtcaaaat aagatactcc ttgattcagc
     4261 tgccaccaat tgttatagcc aaaaatcaaa ctgggtagct cactacgaat gtttcctatc
     4321 aatcgaatgt tgctaatccc tagtatgaaa atgaatacga ccaaagaaaa cagtaaaaat
     4381 ggataaatac gtttgatacg cttatagtaa aaatgtaaaa aactgaattg tctgtttttt
     4441 tcatctctta tcgtattttt agccattaaa aaaccagaaa ccacaaaaaa gatcgttact
     4501 ccttgcaatc cgcctggcag caaactattt ggcaaatgat aaaatatcac tgctaaaaca
     4561 gcaatgcctc taaaacaatc gatttccttt gaatatattt ttttcatgta tcatcaacct
     4621 ccttctcttc atgcatgttt taatcaaaca tattcttccg tatcgatttt ttcatttttc
     4681 tattcgtttc accttgtttt gtaaattaac agttaaaagt atctaaaatg tatctttgcc
     4741 ccatcagttc tcgttgatca caaaaaatat ga
//
LOCUS       DAKCAA010000113         4758 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000113 DAKCAA010000000
VERSION     DAKCAA010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.116"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            157..387
                     /locus_tag="OUE31_002620"
     CDS             157..387
                     /locus_tag="OUE31_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HCU0223581.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            484..1785
                     /gene="murA"
                     /locus_tag="OUE31_002621"
     CDS             484..1785
                     /gene="murA"
                     /locus_tag="OUE31_002621"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCU0223582.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1798..1974
                     /locus_tag="OUE31_002622"
     CDS             1798..1974
                     /locus_tag="OUE31_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCU0223583.1"
                     /translation="MSNQRYIILTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2109..2405
                     /gene="yidD"
                     /locus_tag="OUE31_002623"
     CDS             2109..2405
                     /gene="yidD"
                     /locus_tag="OUE31_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HCU0223584.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2589..3056
                     /locus_tag="OUE31_002624"
     CDS             2589..3056
                     /locus_tag="OUE31_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0223585.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3141..4025
                     /locus_tag="OUE31_002625"
     CDS             3141..4025
                     /locus_tag="OUE31_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCU0223586.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4139..4375
                     /locus_tag="OUE31_002626"
     CDS             4139..4375
                     /locus_tag="OUE31_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HCU0223587.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4463..4543
                     /locus_tag="OUE31_002627"
     tRNA            4463..4543
                     /locus_tag="OUE31_002627"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4497..4499,aa:Tyr,seq:gta)
     gene            4550..4621
                     /locus_tag="OUE31_002628"
     tRNA            4550..4621
                     /locus_tag="OUE31_002628"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4582..4584,aa:Gln,seq:ttg)
BASE COUNT         1600 a          742 c         1041 g         1375 t
ORIGIN      
        1 tctcagtccc tttttttgca tatttttagc atttatttcc taaaaaatgt aaggggattc
       61 ctatattttt aagtatactt gtttttcctt ttatacattt tatggtatta tcattttatt
      121 agttattata aaacaatcgt tagaaaggac gtcattatgc aagtatacgg aattgatgcg
      181 gtgcttcgaa tcgtgagtca tttggcgttt atctacttag ccttctggtc tttacgttcg
      241 ttacgcattg aaactttttt cagaccaatg cataatacgc aaattagaat ggcaatcgta
      301 cttttttcaa tttttttagg gtacactgca agtaattttt tcttagaagt tatcgcttta
      361 tgccgaaatc ttttcgttag cctgtaaatt ttaaaaaaag gtactatttt aaaagcaagg
      421 atgttataat agaaaagatt ttgagtaagt gtatgctcat tggaattttt tggagggaac
      481 aacatggaag agatcatcgt aagaggtggc aatcaattaa atggaacagt aagaattgaa
      541 ggagctaaaa atgctgtttt gcctatttta gctgctagtt tgttagcaga agaaggtatt
      601 acgacattag acaacgttcc gattctttct gatgtcttca ctatgaatca agtgattcgt
      661 cacttaaacg tagatgtaga ttttgatgaa caaaagaatc aagtaacaat cgatgcttca
      721 agacaattag aaatcgaagc gccttatgag tatgttagtc aaatgcgtgc ttcaatcgtt
      781 gtgatgggtc cgctacttgc cagaaatgga catgcaaaag tagctatgcc tggtggatgt
      841 gcgattggta aacgaccaat cgatttgcat ttaaaaggat ttcaagcttt aggagcaaaa
      901 attattcaaa aaaacggcta tatcgaagca attgcggatg aattgatcgg taacacgatt
      961 tatttagatt tccctagtgt aggtgctact caaaatatca tgatggctgc cgtaaaagca
     1021 aaaggaacaa ccatcattga aaacgtagct cgcgaaccag aaatcgttga tttagcaaac
     1081 attttgaata aaatgggcgc tcaagtctat ggagctggta ctgaaacaat gcgtattgaa
     1141 ggcgtggatc atttacatgc agtcaaccac tcaatcgtac aagatcgtat cgaagcaggt
     1201 acctttatgg ttgctgctgc aatgacacaa ggcaatgtgc tgattgcaga tgctatctct
     1261 gaacataacc gcccattgat ttctaaattg atcgaaatgg gtgcagaaat cattgaagaa
     1321 gaaggcggag tccgtgtcat cggaccaaaa catatcttac ctacagatgt aaaaacgatg
     1381 cctcatcctg gtttccctac agatatgcaa gctcaaatga cagctatcca attagttgca
     1441 gaaggtacaa gtgtagtgac tgaaacagtg tttgaaaatc gtttccaaca tttagaagag
     1501 atgcgccgta tgaacgctca tgtcaaaatc gacggaaatg tagcaatcat ggatggaaac
     1561 catgaattgc aaggtgcaga agtatatgca acagacttgc gggcagcagc agcattagtt
     1621 ttagctggct tgaaagcaaa tggaatcaca cgtgtgcgta acttgaatta tctagaccgt
     1681 ggatattata atttccatat caaactacag caattaggtg cagacgttga acgtgtagac
     1741 atggatcaaa cttctgctga aaaaacagca caaacgattg cttaaggaag tggctgaatg
     1801 agtaaccaac gatatatcat attaactttg ataaagattt tagtggtgat cttattgctt
     1861 atccttcttt ttgtggccgg aacgatgatc ggatatggtg tcatcggtgg cggcaatcca
     1921 tttaaagtat tccagccaag tttgtggatt catattcgag acttttttca ttgataaata
     1981 agaatcacag tggttctagt cgatatgaag tgagccatga agcagaacat gacaaaagaa
     2041 aacagaaggg aacgttgacg ttagtcgcga tccctttttt tagtaaaaga aaagaaggaa
     2101 tctaattgat gaagaagata ttgatttatt tagttagagg atatcagcgc tttatttcgc
     2161 ctgcatttcc acctagctgc cgttattacc caacctgttc caattatatg ataaaagcaa
     2221 ttcaaaccca tggtgcacta aaagggacgg taatggggac tgcacggatc ttacgctgtc
     2281 atccttttgt caaaggcggt atcgattatg taccattgac attccaatta acgcgaaata
     2341 agaaagataa aaaagaacca gattataaaa aggttgtgaa aaatacgagt agcactgagc
     2401 gataaagaaa caatttggaa aatagcttct tatattttgc aaaattgtga gttattgccg
     2461 aagtgttgga ttttgaacac cgtcaaaaaa aggttgtgaa aaatacgggt agcactgagc
     2521 gataaagaaa aagaggaaaa ttattgtcaa agtaacaact ccgcaactac ttatatgggg
     2581 gacaaaaaat gatcgaagaa ctaaacaaga aagatttacc atggtccttg ttattagatg
     2641 cagatcctga taaagaaaaa gttcaagtat atgtttccag agggagtggc tggatatgga
     2701 aagaaaaaga aaaaacaata ggtgtactga tctatgtggc aagggaaaaa gaatacgaaa
     2761 tcgtcaatgt agcagtagcc ccaacgtatc aaggaaaggg gattggcgga aaattacttg
     2821 agacagcttt tcagaagctt tcacaactcg cttccagtca aactcagatc atcatacgaa
     2881 ccggcagtac tagcagtgcg gcgttacatc tctatcaaaa aatgggctat gtggagattg
     2941 gtcgagtcaa agactatttt atccatcatt actctgagcc catttttgaa aatggagatc
     3001 aattaaggga tcaagtaatt ttagcaattc acttacctaa aaatagcttt aactaataaa
     3061 ctttcaattc gagaaaatgc tttcaaatgc taaatagata cattacaata gctttagcaa
     3121 acaaaaagga gaatattttt atgggaatat tagtttttga ttttggtgga tcggctgtca
     3181 aatatggttg ttgggatggc aaagagatta aaggtaaggg acaatttgca acgcctgaat
     3241 cttgggaaga aatgaaagcg caattatttc aagtttataa aaaaatactc gtttcttttg
     3301 aagtcgaagg aattggaatc agctctcctg gagtagtgaa taatgagaaa caggtgattg
     3361 agggaatcag tgcgattcct tatattcatg gatttaatat tttccgagat ttggaaactc
     3421 tgtttcaact cccagtaacg attgaaaatg acgccaactg tgccggaatg gctgaatttt
     3481 atgaaggtgc tgcccgtgat tatcaagatg ttgcttttgt tgtggcagga actgggattg
     3541 gcggggcgtt gttcacgaaa ggacaaatca ataaaggggc acatctttat ggtggagaat
     3601 ttgggttgat gttcttaaat ggcgataaga cattcagtaa acttggtaca gcggtacaga
     3661 tggcttggcg ttattgtgaa cgcaaaggtc tcgataaaaa ttcttatacc ggaaaagatg
     3721 tctttgaatt agcagaaact ggagatgcaa tagcaaaaga agaagttgag agtttttata
     3781 cgtatcttac aaagggatta ttcagtattc aattttcgtt tgatccagaa gtgatcgtat
     3841 taggcggcgg tgtttctgca aaagaagggc tcattgatga gatcaaaagc cgaatgaaga
     3901 agctgacaga acaattcgat ctgcatgatt tcgaaccgca gattttatta tgtgaataca
     3961 gaaacgatgc taatcttgta ggtgcagcag caaactatct cgctgtacgt caaggggaga
     4021 attaagagct ttagagaagg tgcagcttgc ataaaagaag tgaatgaaat gaataggaga
     4081 tttttaccta aggaatgttt tatttgctgc agtatgataa aatatctgag aggtgaaaat
     4141 gatgtcaaaa aaaaataaag atgttgaagt gcgtatagaa gaagtgaaaa aagatatcaa
     4201 aggtaagaat tatgaagtca ctcagttatt tatagggaaa aaaatgattg gtgagatctt
     4261 agcctatggg ccaaaagaat atgaaatttt ctttggtgaa gaagattttg gaaaagaaaa
     4321 aagtcttgaa aatgcgatag aaacagtgat tcgacactgg aatctgcacg aataaaaaaa
     4381 tatcaaaaaa actttcaata aagggttgca aaaatctgga aaattaggta ttataactaa
     4441 gtcaggttga tacaaacctt tcggaggagt agcgaagtgg ctaaacgcga cggactgtaa
     4501 atccgttcct tagggttcag tggttcgaat ccactctcct ccatttcatt ggggtatagc
     4561 caagcggtaa ggcaagggac tttgactccc tcatgcgttg gttcgaatcc agctacccca
     4621 gtataccaca atcgtaagct ctcgttagtt cgagagctct tttttttgct ttgctacctt
     4681 gttccttgaa gattctgctg atttaagata gagttaagtt aactacaaga attggaggga
     4741 tccacatgaa atggaaag
//
LOCUS       DAKCAA010000114         4705 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000114 DAKCAA010000000
VERSION     DAKCAA010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.117"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            107..358
                     /locus_tag="OUE31_002629"
                     /pseudo
     CDS             107..358
                     /locus_tag="OUE31_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            451..1245
                     /locus_tag="OUE31_002630"
                     /note="aph(3')-IIIa"
     CDS             451..1245
                     /locus_tag="OUE31_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HCU0223588.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            1655..1738
                     /locus_tag="OUE31_002631"
                     /pseudo
     CDS             1655..1738
                     /locus_tag="OUE31_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            1787..1870
                     /locus_tag="OUE31_002632"
     CDS             1787..1870
                     /locus_tag="OUE31_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HCU0223589.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            1995..2732
                     /gene="erm(B)"
                     /locus_tag="OUE31_002633"
     CDS             1995..2732
                     /gene="erm(B)"
                     /locus_tag="OUE31_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCU0223590.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(2995..3858)
                     /locus_tag="OUE31_002634"
     CDS             complement(2995..3858)
                     /locus_tag="OUE31_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HCU0223591.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAI
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLEKELNRKVSGKEIQPTLERIEQKMVLNKHQETPEFKAIQQKLESLQPPTP
                     PIPKTPKLPGI"
     gene            complement(3860..4132)
                     /locus_tag="OUE31_002635"
     CDS             complement(3860..4132)
                     /locus_tag="OUE31_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCU0223592.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEV
                     NLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
     gene            complement(4149..4358)
                     /locus_tag="OUE31_002636"
     CDS             complement(4149..4358)
                     /locus_tag="OUE31_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HCU0223593.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(4456..>4705)
                     /locus_tag="OUE31_002637"
     CDS             complement(4456..>4705)
                     /locus_tag="OUE31_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="chromosome partitioning protein ParA"
                     /protein_id="HCU0223594.1"
                     /translation="FVPYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVSTW
                     SKNGITEHKGYDKKVLSMYKNVFFEMLERIIQLENEKE"
BASE COUNT         1444 a          793 c          864 g         1604 t
ORIGIN      
        1 tttcttggga gttttgagac tactatatgc gtttttttgt tgatttacca acatgtttag
       61 acattttcct ctaggaaaaa attaactagc accacgggtt atcttttata tagaagatat
      121 cgccgtatgt aaggatttca gggggcaagg cataggcagc gcgcttatca atatatctat
      181 agaatgggca aagcataaaa acttgcatgg actaatgctt gaaacccagg acaataacct
      241 tatagcttgt aaattctatc ataattgtgg tttcaaaatc ggctccgtcg atactatgtt
      301 atacgccaac tttgaaaaca actttgaaaa agctgttttc tggtatttaa ggttttagaa
      361 tgcaaggaac agtgaattgg agttcgtctt gttataatta gcttcttggg gtatctttaa
      421 atactgtaga aaagaggaag gaaataataa atggctaaaa tgagaatatc accggaattg
      481 aaaaaactga tcgaaaaata ccgctgcgta aaagatacgg aaggaatgtc tcctgctaag
      541 gtatataagc tggtgggaga aaatgaaaac ctatatttaa aaatgacgga cagccggtat
      601 aaagggacca cctatgatgt ggaacgggaa aaggacatga tgctatggct ggaaggaaag
      661 ctgcctgttc caaaggtcct gcactttgaa cggcatgatg gctggagcaa tctgctcatg
      721 agtgaggccg atggcgtcct ttgctcggaa gagtatgaag atgaacaaag ccctgaaaag
      781 attatcgagc tgtatgcgga gtgcatcagg ctctttcact ccatcgacat atcggattgt
      841 ccctatacga atagcttaga cagccgctta gccgaattgg attacttact gaataacgat
      901 ctggccgatg tggattgcga aaactgggaa gaagacactc catttaaaga tccgcgcgag
      961 ctgtatgatt ttttaaagac ggaaaagccc gaagaggaac ttgtcttttc ccacggcgac
     1021 ctgggagaca gcaacatctt tgtgaaagat ggcaaagtaa gtggctttat tgatcttggg
     1081 agaagcggca gggcggacaa gtggtatgac attgccttct gcgtccggtc gatcagggag
     1141 gatatcgggg aagaacagta tgtcgagcta ttttttgact tactggggat caagcctgat
     1201 tgggagaaaa taaaatatta tattttactg gatgaattgt tttagtacct agatttagat
     1261 gtctaaaaag ctttaactac aagcttttta gacatctaat cttttctgaa gtacatccgc
     1321 aactgtccat actctgatgt tttatatctt ttctaaaagt tcgctagata ggggtcccga
     1381 gcgcctacga ggaatttgta tcgataagaa atagatttaa aaatttcgct gttattttgt
     1441 acatttaact tgacggtgac atctctctat tgtgagttat tagtggtaca gttttcaacc
     1501 gttttaatta taaaaaagtg gtgcattttt aaattggcac aaacaggtaa cggttattgc
     1561 aggtgtattt cttatctatg ggtttaacat ggattttatc attaaaatca tgagtattgt
     1621 ccgagagtga ttggtcttgc gtatggttaa ccctaaagtt atggaaataa gacttagaag
     1681 caaacttaag agtgtgttga tagtgcatta tcttaaaatt ttgtataata ggaattgaag
     1741 ttaaattaga tgctaaaaat ttgtaattaa gaaggaggga ttcgtcatgt tggtattcca
     1801 aatgcgttat gtagataaaa catctactgt tttgaaacag actaaaaaca gtgattacgc
     1861 agataaataa atacgttaga ttaattccta ccagtgacta atcttatgac tttttaaaca
     1921 gataactaaa attacaaaca aatcgtttaa cttctgtatt tgtttataga tgtaatcact
     1981 tcaggagtga taacatgaac aaaaatataa aatattctca aaacttttta acgagtgaaa
     2041 aagtactcaa ccaaataata aaacaattga atttaaaaga aaccgatacc gtttacgaaa
     2101 ttggaacagg taaagggcat ttaacgacga aactggctaa aataagtaaa caggtaacgt
     2161 ctattgaatt agacagtcat ctattcaact tatcgtcaga aaaattaaaa ctgaatactc
     2221 gtgtcacttt aattcaccaa gatattctac agtttcaatt ccctaacaaa cagaggtata
     2281 aaattgttgg gaatattcct taccatttaa gcacacaaat tattaaaaaa gtggtttttg
     2341 aaagccgtgc gtctgacatc tatctgattg ttgaagaagg attctacaag cgtaccttgg
     2401 atattcaccg aacactaggg ttgctcttgc acactcaagt ctcgattcag caattgctta
     2461 agctgccagc ggaatgcttt catcctaaac caaaagtaaa cagtgtctta ataaaactta
     2521 cccgccatac cacagatgtt ccagataaat attggaagct atatacgtac tttgtttcaa
     2581 aatgggtcaa tcgagaatat cgtcaactgt ttactaaaaa tcagtttcat caagcaatga
     2641 aacacgccaa agtaaacaat ttaagtaccg ttacttatga gcaagtattg tctattttta
     2701 atagttatct attatttaac gggaggaaat aattctatga gtcgcttttg taaatttgga
     2761 aagttacacg ttactaaagg gaatgtagat aaattattag gtatagggca cctctaataa
     2821 ctaccaatta attcacctca aaatgaaatt agaaaaaaac agcgaaattt ttaaatctat
     2881 ttcttatcga tacaaattcc tcgtaggcgc tcgggacccc aacatgagga aatgttttta
     2941 taaaaaaaga gtagttaccg ttttttggta actactcttt tcctttttta aggtttaaat
     3001 acctggaagt ttaggtgttt tgggtattgg tggtgtaggt ggctgcaagc tttccaattt
     3061 ttgttgaatt gctttaaatt caggtgtctc ttggtgttta tttagaacca ttttttgctc
     3121 tattcgttct aaagtcggtt gaatttcttt ccctgatact ttacgattca attctttttc
     3181 taaggtttct tttggactaa tagaaggtgt ttccaaactt gaatagagtt ttactccttc
     3241 tctgttatat agccttatat cgctaaataa gcccgtttta tgaagggttt ctaaattggt
     3301 cggtaagttt ttgacaacaa tatcatgcgc ttgttttggt gttgccctgg ctgtcattgg
     3361 atcatctgca tacatggttt catatcgttc aattgttcct aaatatgagt tgattttagg
     3421 tactgccatg acatacattt ttgtttcata acctttggct tgaagcattg ttgcggtttg
     3481 aataggaacg tctgttgttc gtcctgtacc ttcgatcacc aaattatacc cttgatcgct
     3541 caaacggctt atgatcgctt ctgtcatgcg attagaataa ggggtaacgt gttttactac
     3601 gtctttttca taaagtttca ctagttcatc aaaattaggg tgctgttgtt taaaggtatc
     3661 attatcaatg acaataacat tcccttgtgt ttcttcaaaa attgctgatc gcaaactggt
     3721 tttccctgac cctggttgcc caccaagtaa aaaagcggtt ggcgattcaa ccgctttttt
     3781 tccttgaatc aattcttcta aattatcatt taagcgattc tcaaattgtt tgtcagtaaa
     3841 attgactata tttgccatat taagccactt tctctttatt caaaacttgt tttgagtaac
     3901 gattcattga ccgccaatac tcatgaacgg cttgtaattc ttctaaagaa taatcaaaaa
     3961 gatttacacg ttttgcaagc tttaattggt ttaataaatt gacttccaat aattgagagt
     4021 catttttatt taattcatgg ttcaaaacat agtttaatac tcgattataa acgcttgccg
     4081 ataattcgtt aatgatctct atttcaaatg ttttttcata cgtaactgcc atttcatttt
     4141 cactcctttt aaagtttgtc aggtaaatat ttccgtatat attcttctaa ggcttgatcc
     4201 ataacttctt ttacgtttcc gccattcttt gctgtttcga tttttatgat atggtgcaag
     4261 tcagcacgaa cacgaaccgt cttatctccc attatatctt tttttgcact gattggtgta
     4321 tcatttcgtt ttgctttttg tgcgcctaaa tttcccacaa tcactcactt ctttctattt
     4381 cttcttactc ttattttatc atcaacaatc acaaatcaca agtgatttgt gattaatcac
     4441 ttgtgatttg tgattctatt ctttttcgtt ttctaattga ataattcgct caagcatttc
     4501 aaaaaatacg ttcttataca tggataaaac ttttttgtca tagcctttat gctctgtaat
     4561 gccgttttta gaccaggtac ttactttatt acttcgcttg ataatatttt ggaaaaccaa
     4621 gttatcttct ttatgttgct tatacagttc ttccaggttt gattttatcg ttgcgctgtc
     4681 cgtatcaact aaataaggaa caaaa
//
LOCUS       DAKCAA010000115         4634 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000115 DAKCAA010000000
VERSION     DAKCAA010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.118"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            12..821
                     /locus_tag="OUE31_002638"
     CDS             12..821
                     /locus_tag="OUE31_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCU0223595.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            861..1358
                     /locus_tag="OUE31_002639"
     CDS             861..1358
                     /locus_tag="OUE31_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCU0223596.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(1743..1816)
                     /locus_tag="OUE31_002640"
     tRNA            complement(1743..1816)
                     /locus_tag="OUE31_002640"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1780..1782),aa:Ile,seq:cat)
     gene            2003..2326
                     /locus_tag="OUE31_002641"
     CDS             2003..2326
                     /locus_tag="OUE31_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223597.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2490..2744
                     /locus_tag="OUE31_002642"
     CDS             2490..2744
                     /locus_tag="OUE31_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223598.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            2814..3059
                     /locus_tag="OUE31_002643"
     CDS             2814..3059
                     /locus_tag="OUE31_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0223599.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            3135..3500
                     /locus_tag="OUE31_002644"
     CDS             3135..3500
                     /locus_tag="OUE31_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223600.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(3561..4124)
                     /locus_tag="OUE31_002645"
     CDS             complement(3561..4124)
                     /locus_tag="OUE31_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223601.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         1460 a          824 c          779 g         1571 t
ORIGIN      
        1 aggaagataa aatgaaacta gcagcgattg atttagacgg taccttgctt gatcgaaatg
       61 gaaagatacc agaagaaaat atccaagcac ttcggaaatt tgatgaaaat ggcggaatcg
      121 taaccgtcgc taccggaagg aacagcattt ctgctaaaga tattttttcc gaattaggaa
      181 tcggtggcta tttgatttct tccaatggtt cactgattgc tgaaatgaag gatggaaaaa
      241 tggcgaaagt tctcagacgt tcaaaaatag atagcgatac actgagaaaa gccttcttct
      301 atgctcaaga agcgaaaata tccatcattg ctagccgaga aacccaagat gatcagctga
      361 cattcgatga atcaaatcta gtcaaagatg acccttatta tgaacatttc aatttacaga
      421 accattcttt tgatcaaatt ttaaatatgt tggaagatcc ttctcttagc tatcttaaat
      481 tagcattaac agataagagt gaagaaaaac tacagaagct acaaagagat ctgcaagcag
      541 atggtatcca atcagtattc tctgatccgc atttcttaga aatcacgcct acaggtatca
      601 ctaaagctca ttcacttgtt tttctggcgg attaccttgg aatcgaatcg agtgacatca
      661 tggcttttgg cgatcaagaa aacgacattg ctatgttgaa ttacagcggg ttgagtattg
      721 cgatggggaa tgcacagcga caagtaaaag aaattgcaaa ccaagtaaca ctgacgaatg
      781 aagaagctgg tgttgcttat attttaaaaa acttctatta aaaagaataa aatgacgata
      841 tgaatgtagg aggaaagaaa atgttagtta ttattgatat gcaaaatcat attcttgatc
      901 caaacagcga attttatatt ccagagtcag atcaattggc agaacgtatt gctcaaagat
      961 tagctaaagc acgccaaaat aatgaatata ttctcttcac acgggatata ccagttgaac
     1021 tgaaggacaa agaagaagaa cgagaagatt tgcaattgat ccctcttctt tctccacaag
     1081 aaaatgaacg agtgattaaa aagtattact ttacgattcc acctgaaact ttagctgaaa
     1141 tccaggaaac tttatttgaa agcaaagaag aacaaaaaga gatcgaagta gtcgggattg
     1201 aaacaaactt gtgtgtactc tctaatctga taggcctgca gagtgctttt cctgaagcag
     1261 acttttttgt tgatccaatg ttagtctcca gtagaaaaca cggagaatcc gctttagagc
     1321 tgttgaaaga tttcaacgtc tctatcgtcg aatcataaaa atatctatct tcatttacga
     1381 tatttaacac acaataaaaa aagcacgcag aactgtttta gtcctacgtg ctttttctat
     1441 caaagtagat tggctttttt atgacacaga gtgaaacggc aggctcacga cctctttctt
     1501 aaatggtgtt caatcagctg accctcggta ttagcttaac aaacggcaaa atatgaggaa
     1561 ctatttttcc gtttgttaag ctaatactca ggtcaaaacg ctgatttcac aacctcttcc
     1621 ttaaacggta ttcaaaagct tgcatctgca gtaataagaa cagccaagta aaaacataag
     1681 aagctgtttt tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct
     1741 tatgtacctt gtaggactcg aacctacgac cggacggtta tgagccgtct gctctaacca
     1801 actgagctaa aggtacatca taaataaaat ttatttttgt tacttttcaa ctatagcacg
     1861 aatgacaaac tctcacaagt ttcaaaatat aagtaaaata atattgttat tcttatttct
     1921 tttacttgtg tcataactat tttgttactt taatttttat ttgcttattt tagaaaaaat
     1981 gttattcttt tatttattct caatgttagg agtgattatt ttgccattta ttgcgatttt
     2041 attcgattta gttgcggcag cagcttattt tctccaatta aattatcaaa cctcaggaat
     2101 tctgtttatt ggaatgattt ttcaaggtgt gattaccctt ttgcttcttg tcatgatgct
     2161 cagctataaa ggaaaaagat atgcccgtat tcaaacaaaa gtatttgtta aatatgtttc
     2221 cattcgctat gggatcatca ttctttcctt tttagtgaat gcgatcgtcc tctttttata
     2281 tgtattgaat tacttagata tcaatccatt gattttttct cgatagataa gacacattca
     2341 gcggaacagt tcctgcttat cagcagaaaa ctgttctgct ttttcatttt tcattgatct
     2401 attcttcttt tattttccta gcatttcatt tgtgatgtat gcaataacat gttatctttt
     2461 attatatgaa tcgttgagga gtccgttaca tgattacgtt ggtgagagtt ttgttttggg
     2521 tgcctgcggt cgcactggtc gcaagtattg tttatcttat gaattggaac aaagaacggt
     2581 tttatttagc tattttgact cttccggcta tctactttat gtggaaagtt tttaattaca
     2641 actactttga acccgatagt gtttttatag aagaattatc aggactggtt ttgtctttat
     2701 tgatcgtcat tctttatttg atacgtttaa ataaaaaaca ttgagtacta ttgattgcat
     2761 gtgtagcttt ctatagtcat tataactatt ctactataat gaaaggtgat taaatgagta
     2821 tcgaagaagc tattttactg gatactttac gttgtcgtct gaatttctta agaactggcc
     2881 gatctttatc tcaagtagct gtttctagcg cgttaagtat tcctttattc aaatatcgta
     2941 agtacgaaga aggagaagaa attccaagca tcattgaatt aatctatatc gctgactttt
     3001 acgatatttc cgttgattac ctaattggtc gctcagaaac agcaagcaaa ctgaagtgat
     3061 tttttccagc cttggtgctg gttttttcat ttaacgtcta aggttaacaa tctatatata
     3121 aaggagacat ttctatgcga ttatggcatg aaaaattgat ttcaaagctt cctcgtcaac
     3181 agcttttagg acaacatcgg gaatgctgtg cattaagagg aaatggctgg ggaaagaaac
     3241 atgctactgt ggattatgtt tttcactatt ctccttatag attattccaa tatcatcagc
     3301 ttgtcatgga tgaaatggaa aaacgtggtt acagcccagc accagagtgg aaaaatccta
     3361 tgtatcgtgg caaatcatgc gaagcatttt ttgatttacc tactgtagag cgcaacgtgc
     3421 cgatttatcc ggaacacgat gaagtttatc tagcagaatg tttagcaaat ttggagcaaa
     3481 aaggaattta tcttacctaa tataactaga aaagccttct atctcctctt acttcattaa
     3541 aaagctttaa ccatcttaga tcaagctaaa atgtcgtaag ttttagggtt atcttcatcc
     3601 tcacgtgcaa aactaaaagc gtactctagt tttggttcat cgccaacttc cctagacata
     3661 aatgaacatc tcctgacgtg gtttaaaagt accgcatctt cgacgtctgt atacgatgca
     3721 cagcacagat tgcttctttt gatctttctt ttgatttttc tgttgcttct tctacacctt
     3781 cttcgattac tacatcgatg cttacaattg cttctgccta atattcccat gcatcgtcga
     3841 tttaagcctc tgtagtcact gtgatcgttt ccacatttta actcctctgt cgtggcttca
     3901 gttgattttg tgatcagttc agttgctaag ccagagtcag aacaacctgc cattgctagc
     3961 gttaatattg atagtaaaaa tagttttttt atcataaggt tccccccctg aaaatagact
     4021 aaaataataa cgctttcttt ttttgttttc agacgaaaat taataatttc taaatattct
     4081 ttaaaaaagc ttataactat tatgcctttt ttaatatata acacagttat ttttaaaaat
     4141 aagaatgcta aatcactcta caataacggc gaaagcacaa aaaataaaaa aattattacg
     4201 ttattaaaaa aacagatgaa agatcaggtt ttattagatc tcattctttc atcacttgaa
     4261 gggatttaat gaactacttt ttcctctttg tcgtttttat atattcgtat tccttcaaac
     4321 agtaggatag cctctttcaa tgcttgatat ttgaactgtc cgttacttaa aaatttagat
     4381 gtgccgccct cttcctagaa catattcttt tttacttttt cattaattga cagaccaatc
     4441 gaacgaaact gtaaatttcg ataggataat gattggtcaa actcattcat tttcaagaca
     4501 tctcgattca tattcaagat aggaatcttt ttatcaacat cactttattc gtattttcct
     4561 ctaccataaa agcttcacgc tccacaaaat tgttttatac actactattc agcccattca
     4621 acgaccaatg aatt
//
LOCUS       DAKCAA010000116         4632 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000116 DAKCAA010000000
VERSION     DAKCAA010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.119"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            172..516
                     /locus_tag="OUE31_002646"
     CDS             172..516
                     /locus_tag="OUE31_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCU0223602.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="OUE31_002647"
     CDS             517..936
                     /locus_tag="OUE31_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCU0223603.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFGHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1028..1378)
                     /locus_tag="OUE31_002648"
     CDS             complement(1028..1378)
                     /locus_tag="OUE31_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223604.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="OUE31_002649"
     CDS             complement(1344..2675)
                     /locus_tag="OUE31_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HCU0223605.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2931..3497
                     /locus_tag="OUE31_002650"
     CDS             2931..3497
                     /locus_tag="OUE31_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCU0223606.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3642..3729
                     /locus_tag="OUE31_002651"
     tRNA            3642..3729
                     /locus_tag="OUE31_002651"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3674..3676,aa:Ser,seq:cga)
     gene            4063..>4632
                     /locus_tag="OUE31_002652"
     CDS             4063..>4632
                     /locus_tag="OUE31_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HCU0223607.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAARVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT         1682 a          778 c          891 g         1281 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattgaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg taggatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga cgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggcaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaatttttg aaccaggttg tcgcaatcac tggcatgtcc ataaagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttggacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat agtagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagtacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcgagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cctatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc aaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtagaccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataatg cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaac cgcctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt
     2761 aagggaaccc attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga
     2821 ctgaaaaaaa atttaaaata taacgttttg agtaaaatgt ttgcaaaaaa tgctaaaaat
     2881 agggtacaat aaaacaacat atactgcagt aaagaagtgg gggagtttta atgagaagaa
     2941 aagtctatac caaggatcaa attctaaaag ctgcttatga tgttgttgca aaggaagggt
     3001 ttaaaggatt tactgcgaga aatattgcta aaaagatggg gatttcgaca cagccgattt
     3061 atctggaatt caaaaacatg gaagatttaa aaaatacgtt gctggattct atctttgaac
     3121 aactaaaaga agatgttttc cctattgaac gtactggtga taaaatcatt gatctcggtt
     3181 tgaactatat ctactttgca aaaaagcatc atagtcttta catggcattg tacattgatg
     3241 aacatgggga cggaaagaaa atgcatgatt tttcatacaa ttatttccgt gaaatagtta
     3301 aagaagatga aagatacaat caattatcgg atgaatatgt cgatgctctg catactggta
     3361 catgggtagc agtgactggc ttagcgtcat tgatgtcatc aaacatcatg catccaacag
     3421 aagaacaaat cattgcactg atcaaacgga caattgactc gattttagca ttagataatc
     3481 ctgaaataat cagatagtgt tctatcagta tgaatttgat cggtaagtcc gttggctgca
     3541 aactgtcaat ggactttttt gctaaaaaaa gcgatttctg ttatttatct attagaaata
     3601 ggcttgacat ttcgtgaaaa aagtttaaaa atagtactta cggaaggttg gcagagtggt
     3661 aatgcaccgg actcgaaatc cggcgaaccg gctaataccg gcgcgcaggt tcaaatcctg
     3721 taccttcctt atatcaacga ttagaggttg tgaagaagct gtcctgcatc aagtaataag
     3781 aacggccaaa caaaaatagc ttttcctatt ttttcgtttg attgggctta ttaccgcaga
     3841 tgcaagcttt tgaacaccgt ttgttcggaa taaggggctg tgacaagact tttgtcacag
     3901 ccccttattg ttgtactttt aacctacaat attttttgat tccccctgag tactattttt
     3961 tataaatgct agtaaatcaa tcttctttgg cctttttttg ataaaaaaaa tactagatgt
     4021 aagataaaag tgtaaaaacg atttgtttta ggaggggaaa cgatgtgtac cgcaatcact
     4081 tatgcaacga aagaccatta ttttggaagg aattttgatt atgagatgtc ttataatgaa
     4141 gtggtcacta ttactccaag aaattatcgt ttcgatttta gaaaggtaaa aaatttagat
     4201 aaacattatg caatgatagg aatagcagct agggtatcca actatccact ctattatgag
     4261 gctacaaatg aaaaagggtt gagtatggca ggactgaatt ttcctggcaa tgctgattat
     4321 aaagaattac aagaaggaaa agataacgtt gcaccatttg agtttattcc atggatacta
     4381 gggcaatgct caaccataga cgaagctaaa gaattattgg ctactatcaa tctagtcaat
     4441 atcgatttta gtgaaaaact acccttgtca cctttacact ggttattagc tgataaagaa
     4501 aaatcgatag taattgaaag tatgaaagat ggacttcatt tatatgataa tcctgtcggt
     4561 gtgttgacaa ataatccgcc atttgattat caattattta atctgaacaa ttatcgctcg
     4621 ctatcaaatg ga
//
LOCUS       DAKCAA010000117         4592 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000117 DAKCAA010000000
VERSION     DAKCAA010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.120"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(220..972)
                     /gene="xth"
                     /locus_tag="OUE31_002653"
     CDS             complement(220..972)
                     /gene="xth"
                     /locus_tag="OUE31_002653"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HCU0223608.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            1085..2005
                     /locus_tag="OUE31_002654"
     CDS             1085..2005
                     /locus_tag="OUE31_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCU0223609.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2078..3013
                     /gene="murB"
                     /locus_tag="OUE31_002655"
     CDS             2078..3013
                     /gene="murB"
                     /locus_tag="OUE31_002655"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HCU0223610.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            3311..>4592
                     /locus_tag="OUE31_002656"
     CDS             3311..>4592
                     /locus_tag="OUE31_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223611.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVK"
BASE COUNT         1605 a          746 c          895 g         1346 t
ORIGIN      
        1 atctgcggta ataagcccaa ccaaacgaaa aatatgagga actatttttg tttggctgtt
       61 cttattactt gatgcaggac agctttttca caatctctcg ataaacagtg ttcaaaagcc
      121 agtttctcgg tattatgcca aatttatgca aaatgtggaa agccattttc acaaaatttt
      181 tcttaatact cgaaactaaa cgactttttc acaacctctt tatttcaaat ctaattctac
      241 tggacaatga tcactgccca taatgtccgt atggatcttt gcatcagcta gtcctggctc
      301 taaatctttg ctcgtcaaaa agtaatcgat ccgccaacca gcattgtttt tccttgaatt
      361 gaatcggtag ttccaccaag agtagacacc ttcctgggtt ggataaaaat aacggaatgt
      421 atcgataaac ccgttatcca acagtcgaga aagagccgct ctttcttctg gagtgaatcc
      481 agcatttttt tgattcgttt tccagttttt caaatcaatc ttttgatgag cgacatttag
      541 atccccacac acgatgactg gtttttgttt ttttagattt tccaaataat tataaaaggc
      601 ttcttcccat tctaatcggt aatctaaacg ttttaattcg ctttgagaat ttggcgtgta
      661 acaggttaca agaaagaaat cggaatattc caaagtaatc agacggcctt ctgtatcatg
      721 gatatcgata cccattccgt aagtggcatt caatgctggt tttttagcaa aaatcgctgt
      781 gccggaatag ccttttcgtt ccgcgtaatt ccaatattga taataacctg gaagatctaa
      841 atcaatttgt cctgcttgga gtttcgtttc ctgcagacag aaaaaatcgg cgtctaactc
      901 atgaaaaact tctaaaaaat ttttatttac gatggcacga agcccgttta cgttccaaga
      961 gataaatttc aataaaagca cactccttcg aattaatttc cttacctttg cgatactatt
     1021 gtacctcatt ttagtaaaaa atggtgtaag atgaaagtaa ctaaatgatc caggaggaaa
     1081 gtagatgaag attggtgtaa tcggtgtagg gaatatcgca gaaaaagcat atttaccaac
     1141 ttatgcgaaa aaacaaggaa cacttgattt ttattttgca acaagaaata aagaaacaaa
     1201 agaaagaatt caaaaagagt acgggttcca acatctatat gaaacgatcg atgagctttt
     1261 agaagaaaaa atcgaagcat gtatgatcca cgcagcaaca aaagtacatt atgaattagc
     1321 caaaaaatgt ctagaaaatg gtatccatgt ttatattgac aaaccactga gtgtccatct
     1381 aaatgaagtt cgtgaattgc aagaattagc tgataagaac caaataattt tgatgatcgg
     1441 tttcaaccgg cgctttgctc ctatggtaga agaattgaaa cgtatcccag ataagcggtt
     1501 gatccacctg caaaaaaatc gaatagcggc aaaagaaacg acagagttcg tcctttatga
     1561 tttgttttta catcttattg atacagctgt gtatttatta gatgaaccca ttttgagaac
     1621 aaaataccag ataagagaaa caaaggaatt tttggaatat gccattttac aattagaaac
     1681 acaaaatcaa acggctattt taacgatgga tttagcaagt ggcgctaata tagaaaaata
     1741 tcaagtaaca agtaaaaatg gtacttatga agtaaacgat ctgacccagc ttgtcattca
     1801 agatgctgat ggaaaaaaag tgaaagaatt tggcgactgg acaaacacgc tagtcaaacg
     1861 cgggtttgag ccaatggtag aggccttctt ttctcagatc cgtttaggta aatcggaaac
     1921 agaattgctt aaacaaaaag aagttgtaag aagtcatgaa ttatgtgagg aagtgcttaa
     1981 agatcactac cgtcatcaac tttgaacaag actggcaaga ttgtattaag cgtgatagaa
     2041 taatgaggac gtttgagaaa agaaaggaaa atcctcagtg aataaagaag aaatagttga
     2101 aagcttagcc acgattacta tattgtttga tgaaccattg atgaactata cgtttacgaa
     2161 aacaggtgga ccagctgatg tccttgcatt cccgaaaaaa caagaagaag taaagcaaat
     2221 catcgattat tgccgaatcc atgatatacc ttggatggta ttaggaaatg caagcaatct
     2281 gatcgttcaa gatggcggga ttcgcggtgt agtcatcatg ctgactgaaa tgaaacagat
     2341 tcatgtcaaa ggaacgatgg tcattgcgga agcaggtgcc tcactgattg atacgactta
     2401 tgcagctttg gcagaatcat tgactggatt tgaatttgct tgcggcatcc cgggaagtgt
     2461 cggtggagcg gtttatatga atgcaggtgc gtatggcgga gagatcaaag atgtttttgc
     2521 tgaagtggat cttttgcttg aagatggaac attgaaaact ttgacaaaag acgaaatggt
     2581 attttcttat cgtcacagta aagtccaaga attacgtgct atcgtattgg aagctcgatt
     2641 cagtttgcaa acaggggatt atgaagcaat caaagcaaga atggatgagt tgaccgaatt
     2701 gcgtcaatca aaacagccat tagaataccc ttcatgcgga agtgtcttta agcgcccagt
     2761 aggacactat acaggtcagc tgatccaaca agcaggattg caaggcctga aatggggcgg
     2821 tgcacaagtc tctgaaaaac atgctggatt catcgtcaat atcgatcatg cgacagcgac
     2881 agattatatt gaattgattg cgcacatcca agaagtaatc aaagaaaaat ttgatgtgtc
     2941 tttagaaaca gaagtgcgga tcattggaga aaaacaagca atatcagaaa caagcagaag
     3001 tttagccaat taataagtaa tggaacttaa aataagtaaa agagcaggac ggtggccgtc
     3061 ctgctctttt ttgtggttgt ttacgcaaat ggcgcaaatc ttgtacattt taacacaata
     3121 aaacaaaaaa tatagaatat ttcctcataa atttttccat tttttgcaat attctcaaaa
     3181 aaaagataaa aaatgagaat aactgatgaa aaaacaagca taatccatca taaaatcagt
     3241 ataggtgaaa agatgaactt tcatctgcat atcaagtaat tggtatgagg cattttttga
     3301 ggtgtaggat atgaagttgg attaccttat agaagaggaa gatagagaaa aactgctgct
     3361 agctagatat ttagaatttg agaaaaagaa ttatgtagtg ctgcctaagt tatatgaaac
     3421 attaggtttg tctaaattta aaacaagaaa ttatatcata gaattaaata aagaatttac
     3481 tgaattcaaa acaaagccag agatccaaat ttcagaagaa gcagagatcc atgtcgaacg
     3541 tctgaatttg acggatatca aaaatttaag aagaatctac tttcaacgat caaaaattgc
     3601 tcgactgtta acggagatcg tggattcaaa agtaacgatc gaaaaatttg cagagaatca
     3661 ttttttaagc atatcaagag cctatgtaaa aagaagagaa ttagtctctt ttcttgaaca
     3721 gcatcaaata aagttaaaga aaaacatatt agttggggaa gaaataaaca tacggaacgt
     3781 attatttggg gtatatttcg gggtctttaa tggtttttct atgccattta gagaaagcgt
     3841 catgaatgaa gcaaagagta tcgtgcaata ttttgaatat ctgttcaatt taaaactgtc
     3901 tgcaacaaaa cgaatcaaat tcaatttgct aaccactatt agtttgttga gggcctatgg
     3961 gaatcaacca atcggaaaac gtttcttttc agatgaatac tttaagagct cagaaggaat
     4021 gaagatcatc aaggatttat cacatatttc ttttcttcat atccctaaag agcagatcat
     4081 tgatgagatt tcttatatca tgttgttttt gatcacggaa gaagaatttg aattagatgg
     4141 cgcatttgga cttgcggaag ctcattttca tgatatccac atgattagtc aaaaaatgtc
     4201 agtggaattg attgatcaat taccattttc gattgaaatc tctgaagaag aaagactata
     4261 tatacgaaaa gaacttcgta tgggtatgat gcatgtcaat cgaaaaaatt ggatattcga
     4321 ctttgagatg actagcttta cgtctaaaaa gcagctacag tttttcttcg agacgtatcc
     4381 aatattcagt acagcaatcc aaaaggtcat acaagagaat aaacgctatt tcttgggaaa
     4441 agatgaacgt ttcatgattc gcttatttta tgattatctc tttttattgg tcggtatttg
     4501 tccggtatca tattttgaag caccgattca tgtctgtatt gatttttcgc aaggatctgc
     4561 ttataccgat tacattattt ctcaagtgaa ag
//
LOCUS       DAKCAA010000118         4579 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000118 DAKCAA010000000
VERSION     DAKCAA010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.121"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..1167)
                     /locus_tag="OUE31_002657"
     CDS             complement(<1..1167)
                     /locus_tag="OUE31_002657"
                     /inference="COORDINATES: protein
                     motif:HMM:NF021909.1,HMM:NF037690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding adhesin SdrG C-terminal
                     domain-containing protein"
                     /protein_id="HCU0223612.1"
                     /translation="MVGKNNKKLLELKSNPIIKKWRISRLKTGVASIVIFSGVLLSST
                     IFIPLHTVSAEETVTTTYYDQSKNVSDQLTNINISISNNKEKVIFPHNAESLTSNYAF
                     KVPDSVNPKDYFYIDLSENANFYGVTEANSVTMPNLLAPDNSIIATGKYDIDTNRIQY
                     EFTDYVAVHDNVSGKISLPIFIDPEVVTNTSYQTITASIGNSKKDLSLLVDYSKNVGP
                     QYNANGAGNIFNVDLNNHNFSHTIYVNSLKQTLGNKSIEIRNQRKEENGYNSEIIYDK
                     TNTQIKVYKVKSNGRLTDSFSIATNDSLEDVTNQCYIDFYDNKINISFPSNIDNETYV
                     VQYTSPYTDKKDIATRVVMYGYSPYQLGNTSWYWDNYVKLTDGNASGDGSVISPD"
     gene            1496..2767
                     /locus_tag="OUE31_002658"
     CDS             1496..2767
                     /locus_tag="OUE31_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HCU0223613.1"
                     /translation="MNVFDATLKRLEYIFEEFDKVYFSFSGGKDSGIMVQLANLVAEK
                     LDRNFDLLILNIEANYTATVDFIKKIEQLPRVKNIYHFCLPFFEDNNTSFFQPQWKMW
                     DPSEKEKWIHSLPKNAITLENIDDGLKKYYSLSNGNPDRFLRYFQNWYKEQYPQSAVS
                     CGVGIRAQESLHRHSAVTKGENKYKNRCWINITLEGNILFYPLFDWKVDDIWAATFKC
                     GLEYNYIYEKMYKIGYKYRDMRICQPFGLQQRKALNQFAELEPETWDKLVKRVSGVNF
                     GNIYGKTSLLGLNTSQKPSFMTWQRYSIFLLETLGLYSPLLMNHYYRKICILFAYYKN
                     KYNMDIQDMPDESKRKDWIKDERLWNDWKGIAKALEKNDFVLSTRNYSLTKKDEAELY
                     EMFKEYKDFLGINQLKGKRYENIVQKIGGMK"
     gene            2764..3189
                     /locus_tag="OUE31_002659"
     CDS             2764..3189
                     /locus_tag="OUE31_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223614.1"
                     /translation="MSEIDIKVYIPPYNKQNFYSLMGKYFAERVYRRKLPYLINTPST
                     IWFLLMNKERIIGFSSIQISNEFIDIGDVFVEDENDDTRKYLLEKVLFFIDKKCERKC
                     VRISLKKDQYLNNLKHYCFKQYRETKNYLFFRREINEQD"
     gene            3176..3709
                     /locus_tag="OUE31_002660"
     CDS             3176..3709
                     /locus_tag="OUE31_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HCU0223615.1"
                     /translation="MNKIDMPVLNVKMVPVEKIKSNNYNPNHVAEPEMELLELSILKD
                     GYTQPIVCYYDDKKDEYIIIDGFHRYLIGKSKLDLKELPLVVIDKPLEQRMSSTIRHN
                     RARGKHEIDKMSELVLLLVNEGWDDHKIGKELGMEKEEVLRLKQVTGLKSAFLNHEFS
                     ESWDEFVKKNYPKQKDE"
     gene            3843..4310
                     /locus_tag="OUE31_002661"
     CDS             3843..4310
                     /locus_tag="OUE31_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HCU0223616.1"
                     /translation="MKFCETKKVLNQLVADLSVFSVRIHQVHWYMRGERFLFLHPKMD
                     DLMEQINDQLDVISERLITLDGSPYSTLEEFFTNSKLEEEKGSWNKTIDEQIDYLLEG
                     YNYLVSTYEEGIETAGKEGDDCTEDIFIGSKSELEKEIWMLKAELGNSPELDK"
BASE COUNT         1722 a          521 c          750 g         1586 t
ORIGIN      
        1 atcaggtgat atcacactac cgtcaccact tgcatttcca tctgttagtt ttacataatt
       61 atcccagtac cagctagtat tgcctaattg ataaggagag taaccataca taactactct
      121 agtagcaata tcttttttat ctgtataagg agaagtatat tgaacgacat aagtttcgtt
      181 atcaatattg ctcggaaaac taatattaat tttattatca taaaaatcaa tatagcattg
      241 attagtcacg tcttctagtg aatcatttgt agcaatagaa aaactgtcgg ttagtcttcc
      301 gtttgatttt actttataaa cttttatttg agtatttgtc ttatcgtaga taatttcaga
      361 attatatcca ttttcttctt ttctttgatt tctaatttca atacttttat ttcctaaagt
      421 ttgttttaaa gaattgacat agatagtatg agaaaaatta tggttattca agtctacatt
      481 aaatatgtta ccagcaccat tagcattata ttgaggtcct acatttttag aataatccac
      541 taacagactc aaatcttttt tactattgcc tatactcgca gtaatagttt gataagaagt
      601 attagttact acttctggat caataaagat cggtaaagaa atttttccac taacattatc
      661 atgcactgct acataatccg taaattcgta ttgaatacga ttagtatcaa tatcgtattt
      721 tccagttgct ataattgaat tatctggagc taagagatta ggcattgtga cagagttagc
      781 ttctgtaact ccataaaaat tagcattttc actcaagtca atataaaaat aatcttttgg
      841 attaactgag tcagggactt tgaatgcata atttgaagtt agcgattctg cattatgtgg
      901 aaatatgact ttctctttat tattagatat tgaaatatta atatttgtta attgatcact
      961 aacattttta gattggtcat aataagtagt agttactgtt tcttctgctg aaacagtatg
     1021 taaaggtata aaaatagtag aacttaataa taccccgcta aatatgacaa ttgatgcaac
     1081 tcctgttttc agtcgactaa ttctccactt tttgataatt ggattgcttt ttaattctaa
     1141 taacttttta ttgttttttc caaccataaa attatccttt ctacataatt tattcgaacg
     1201 ataaaaatga tcgttcattt tcattataat aatatttaat ggaaaaacaa gttaaaaata
     1261 ttgtttgaat aataattcca attatttcta taatatttgt taactgtaag atactactag
     1321 actaaaatcc atttttgttt ttttaagtaa gtatagtata taaattaaag gtgttcctta
     1381 cattattcta tatgatttga atactataag aaacaacaat tgataaaatt attgacaaag
     1441 tttttaaagg tattaccatt gatattgaac gcttattttt ttagggggat gagaaatgaa
     1501 tgtctttgat gctactttaa agagattaga atacatattt gaagaatttg acaaggtgta
     1561 tttttcattt agtggtggta aggatagtgg gataatggtt cagttagcta atctagttgc
     1621 agaaaaatta gatagaaatt ttgatctatt aatattaaat attgaagcaa attacacagc
     1681 aactgttgat tttataaaaa aaattgaaca gttacctaga gtaaaaaata tttatcattt
     1741 ttgcttacct ttttttgagg ataacaacac tagttttttt caacctcaat ggaaaatgtg
     1801 ggatccaagc gaaaaagaaa aatggattca ttctcttcct aaaaatgcca taactttgga
     1861 aaatattgat gacggtttaa agaaatatta ttcattatca aatggtaatc ccgacagatt
     1921 tcttcgttat tttcaaaatt ggtataaaga acaatatccc caaagtgctg tatcatgtgg
     1981 tgtaggtata agagcacaag aaagtttaca tagacatagt gctgttacaa aaggtgaaaa
     2041 taaatataag aatcgatgtt ggataaatat aactttagaa ggaaatattt tgttttatcc
     2101 tttatttgat tggaaagttg atgacatttg ggctgcaact tttaaatgtg gactagaata
     2161 taattatatc tatgagaaaa tgtataagat tggatataag taccgggaca tgagaatatg
     2221 tcagcctttc ggattacaac aaagaaaagc gttaaatcaa tttgctgaac ttgaacctga
     2281 aacatgggat aaattagtaa aaagagtaag tggagttaat tttggaaata tatatggtaa
     2341 aactagtctt ttaggattaa atacttctca aaaaccttca tttatgactt ggcaaagata
     2401 ttctattttt ttactagaaa cattaggatt atattctcct cttttaatga atcattatta
     2461 cagaaagata tgtattcttt ttgcttatta caagaataaa tataatatgg atatccaaga
     2521 tatgccagat gaatcaaaaa gaaaagattg gataaaagat gaaagacttt ggaatgactg
     2581 gaaagggata gctaaagctt tagaaaaaaa tgactttgtt ttatctacta gaaattatag
     2641 tttaacgaaa aaagatgaag ctgaactata tgagatgttt aaagaatata aagacttttt
     2701 gggaataaat caattaaaag gaaagaggta cgaaaatatt gtacaaaaaa taggaggaat
     2761 gaaatgagcg aaatagatat taaagtttat atacccccat acaataaaca aaatttttac
     2821 agtttaatgg ggaaatattt tgctgaaaga gtatatagaa gaaaattacc ttatttaata
     2881 aatacaccta gtactatttg gtttttgtta atgaacaagg aaaggataat tggattttct
     2941 tccatccaaa tttccaatga gtttattgat attggagatg tttttgttga agatgaaaat
     3001 gacgatactc gaaagtatct attggagaag gttttatttt tcatagacaa gaaatgtgaa
     3061 agaaagtgtg tacgaatttc tttaaaaaaa gatcagtact taaataatct gaaacattat
     3121 tgttttaaac aatatagaga gacaaagaat tatttatttt ttaggagaga aatcaatgaa
     3181 caagattgat atgcctgttt taaatgtaaa aatggttcca gtagagaaaa taaaaagtaa
     3241 taattataac ccaaatcatg tcgctgaacc tgaaatggag cttttagaat tatcgatttt
     3301 aaaagacgga tatacacaac caattgtttg ctattatgat gataaaaaag acgaatatat
     3361 tattattgat gggttccata ggtatttaat tggaaaaagc aaacttgatt taaaagaact
     3421 tcctttagtt gtaattgata agccattgga gcaaagaatg tcaagtacaa ttagacacaa
     3481 tagagctaga gggaaacatg aaatagataa aatgtccgaa ttagttctac tgcttgtcaa
     3541 tgaaggatgg gacgatcata aaatagggaa agaactagga atggaaaaag aagaagttct
     3601 tagattaaaa caagtaacag ggttgaaaag tgcctttttg aaccatgaat ttagtgaatc
     3661 atgggatgaa tttgtaaaaa aaaattatcc taaacaaaag gatgaataag tggtaaagat
     3721 ttttataaac acgattttaa tataaacgtt cattttattg ttgacaagat atatttgtta
     3781 tattaaatta tgtgtaaatc agaattattt cttttaaaaa aatttaaatt aggagtgata
     3841 ttatgaaatt ttgtgaaaca aaaaaagtat taaatcaatt ggtagccgat ttaagcgtat
     3901 tttcagtaag aatacatcaa gttcattggt atatgcgtgg agaaaggttt ctatttctac
     3961 atcctaaaat ggatgatctc atggagcaaa ttaatgatca gttagatgta atttcagaac
     4021 gactgattac acttgatgga tctccgtatt caactctaga agagtttttt acaaattcca
     4081 aattagaaga agaaaaaggc tcttggaata aaactattga tgaacaaatt gattatttat
     4141 tggaaggtta taattatctt gtttcgacat atgaagaggg gattgaaact gcaggaaagg
     4201 aaggcgatga ctgtacagag gatattttta ttggttctaa atcagagcta gaaaaagaga
     4261 tttggatgtt aaaagcagag ttaggtaact cacctgagtt agataaatag atacagaact
     4321 tcaagtgaat ggttatgata tttccttgtg aatagggagt gtttttcagt gtttctatga
     4381 atactataag tgagattgat aaaaaaacaa aaacatctaa ggagagattt atttctacct
     4441 tagatgtttt ttcactaagt gatctgtttc agtcgataaa tataagtgca ggtagatttt
     4501 aacaactaat tatatcaaag aaataagtat atagtactgt aaaaatatat attataaatt
     4561 atcttaacaa agagttgat
//
LOCUS       DAKCAA010000119         4548 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000119 DAKCAA010000000
VERSION     DAKCAA010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.122"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            363..632
                     /gene="rpsN"
                     /locus_tag="OUE31_002662"
     CDS             363..632
                     /gene="rpsN"
                     /locus_tag="OUE31_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCU0223617.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAVGDHTDLAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            647..826
                     /gene="rpmF"
                     /locus_tag="OUE31_002663"
     CDS             647..826
                     /gene="rpmF"
                     /locus_tag="OUE31_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCU0223618.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            858..1235
                     /locus_tag="OUE31_002664"
     CDS             858..1235
                     /locus_tag="OUE31_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223619.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDTQQIQAYLEDR"
     gene            1256..1405
                     /gene="rpmG"
                     /locus_tag="OUE31_002665"
     CDS             1256..1405
                     /gene="rpmG"
                     /locus_tag="OUE31_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCU0223620.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1429..2412
                     /locus_tag="OUE31_002666"
     CDS             1429..2412
                     /locus_tag="OUE31_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCU0223621.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKHYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2442..2564
                     /locus_tag="OUE31_002667"
     CDS             2442..2564
                     /locus_tag="OUE31_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCU0223622.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            2582..4105
                     /locus_tag="OUE31_002668"
     CDS             2582..4105
                     /locus_tag="OUE31_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCU0223623.1"
                     /translation="MKKISVGLVGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            4129..4368
                     /locus_tag="OUE31_002669"
     CDS             4129..4368
                     /locus_tag="OUE31_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223624.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSV
                     DTVRRVLKQDRDCCFIKVNTGRSRRLAKRYNSLIN"
BASE COUNT         1704 a          635 c          885 g         1324 t
ORIGIN      
        1 ttggtcacaa tcttacaaaa tcattaataa acgagttaaa cataaaagat tgaataaaac
       61 tatagtttct ttcataatgc cgttttaagt agagaaaagc tacttaaaac ggtatttatg
      121 ttttaatgga ctaataaaaa tgaaccatta ttttttgcac ttaaactaca agttctttta
      181 attaatctga ttatctctat gtatcgataa aatcattttc aaatggatat ctattcatat
      241 gatttttatt tcatgttatt tattgttgac aagagaaatt tttgttggta aagtgtcaat
      301 gtcaaaacgt aacgtttacg atttgtgacg tctaaatcaa aacagaagga gtataaatgt
      361 atatggcaaa aaagtctaaa attgctaaag caaagaaaca aatggcaatg attgaaaaat
      421 atgcagacaa acgtcaagaa ttaaaagccg taggagatca caccgacctt gctaaattgc
      481 caagagattc aaatccaaat cgtctgaggc ttcgtgatca gacggatggc cgtccaagag
      541 ggtatatgcg gaagtttggt atgtcccgta ttaagtttag agagcttgcc catcaaggtt
      601 tgattcctgg agtaaaaaaa gcaagttggt aagaggagga aatatcatgg cagtaccagc
      661 aagaaaaaca tctaaggcga agaaacggtt aagaagaact catcaaactg tagtaaaacc
      721 agaaatttca tttgacgaag cgaatggtga ttatagacgt agccatcatg tatctttaaa
      781 agggtactat aatggaaaga aagtaattaa aggagcttca aaatagttta atatataact
      841 tttaggaggg aaccaaaatg gaaattattt acccaccttt agttgaagaa ggattaaagt
      901 attatcttga aacgacccag caatcgctag ataaatgcac tttttatcgt tcgatggtag
      961 agagaggaat tattactgaa acgggtttac cgacccaaca ggcaattgaa aatggattag
     1021 tcaaagatta ctatgaggac caaggcttat catttgatga ttttttaaga atctatccaa
     1081 tttttgaaga gtatgacgag gagttatttc aatgtatcga tggttattgg gagatacctg
     1141 ttgatatgaa agaaaattta gtttcacaat tggaatctgg cgagttaact tttgaagata
     1201 cacaacaaat tcaagcatat cttgaagatc gataagtatt gaaggaggaa gatttatgcg
     1261 tcaaaatatt attttggaat gtgtcgaaac tggagaacgt ctgtatctca ccagcaaaaa
     1321 taaacggaat aaccctgaac ggttagaatt aaaaaagtat tcgccaaaat tgcgcagacg
     1381 ggcaattttt aaagaagtga aatagctaag tggtaaaaag gtgacaaaat gggcatacca
     1441 gttacaatcg tttctgggtt tttaggggct ggaaaaacaa cgctaatcaa tcaagccttg
     1501 caagtctcac cctaccccag ggaagaaatt attataattg aaaatgagtt tggtgaagtt
     1561 gggattgatc acaaattatt agttcatagc gaggaacggg tgttacaact aaataatgga
     1621 tgtatgtgtt gcagtcttcg cagtgattta ttagcaatat tgatttcttt actggaaaca
     1681 atagaagaac atcaacaacc aatttcacaa atcatcattg aaactacagg tatagcagat
     1741 ccccaaccaa tcattcaaac acttttaaca gcgcctcaac taagaggaag agtatatatc
     1801 gatagtttat tgactgttat tgatagtgac agttttgaac ttattgaaag agaaccacaa
     1861 gcccttaagc aacttgtcat ggcagatcgc atttttgtgt ctagaaaaca aaacttgaat
     1921 ttatctgcac taaaaaaatt acagagagaa atcaaaagta ttaacccttt atccgatatt
     1981 cgaatgttca cacatagtga aacgattcaa aaaaaggatt tttataattt gaaaaaattt
     2041 aatcatccct tagtttttga aagtgattca tcagaaaatc actataatgg caaacactat
     2101 catcaacacc atcaagtaca tgagtttaaa tcaattctct taacttcaga tcaagacata
     2161 aaaaaagatt ttttactcca atggattgac tggttgattt taaccaacca agggagcctg
     2221 tatcgtttta aaggattgat tgctttacaa gagcaggatt ttatagttgc catgcaaggg
     2281 gtaaacgaac aggttaattt tcaatacacc actcgacaaa aagaccaaac cactattatt
     2341 ctaatcggaa aaatgttgga tgaagaaagg atcaaacaga gttttgataa attactggcg
     2401 gaaagcaaat aatgataagt attgattggg ggtaatttct aatggagaaa acggatatat
     2461 ctagtgcata tcgacgactt aaaagcccga atattaaaac tagaaaaagg gcattaaaaa
     2521 ttatcaaaga acataaacga aataaaatga agaaattagc ataattaagg aaggaaaaag
     2581 aatgaagaaa atcagtgtag gacttgttgg gatagcagct ctaggattat tgggagcttg
     2641 ctccagcact aatgatgcaa aagtatcgaa tgataaagat ggaaaattag aaattgtaac
     2701 aacattctat ccaatgtatg atttcaccaa aaacatcgtc ggcgatgaag cgaacgtgga
     2761 tttaatggtt ccagcgggat cagaacctca tgactatgag ccctcagcta aggatatggc
     2821 aaaagctcat gatgctgatg tttttgtata tcataacgaa aacatggaat catgggtacc
     2881 aaaagctaaa gaaagttgga agaaagctgg gcctaatgta gtagaaggaa caaaagacat
     2941 gattttattg ccaggtagtg aagaagaaga tcatgatcac ggagaagaag atcaccatca
     3001 tgaactagat cctcatacgt gggtttcacc caaaatggca attaaggaag tttcaaatat
     3061 caaggatcag ttagttaaat tgtatccgaa aaaagcaaaa gtatttgaga caaatgctga
     3121 aaagtatttg actaaactga aacggttgga tgctgactat accactagtc ttaaagaagc
     3181 gaaacaaaaa agttttgtga cacaacatgc agcctttgga tatttagctt tggattatgg
     3241 attgatacaa gttcctattg ctggactaag tcctgaagaa gagccatctt ctggtcgatt
     3301 agctgaatta aaagagtatg ttaaaaaaaa taagatcaat tatatttatt ttgaaaagaa
     3361 tgctaatgat aaaatcgcaa aaactttggc caatgaagct gggataaaat tggaagtatt
     3421 gaatcctctt gaaagtctta caaaagaaca aatggataat ggtgaagatt atgtttcagt
     3481 aatggaagac aatctaaaag cgttagagaa aacaactatg gttgctggtg aagaggtagt
     3541 tccagaaaaa gaagcgaagg atgaaaagac agttgctaat gggtacttta aagatgccga
     3601 tgtgaaggat cgcgaattga gtgattatac aggcgaatgg caatctgttt atccgttgtt
     3661 aaaagatgga attttggatg aagttttcga ttacaaagca aaactcaata aagacatgac
     3721 agctgccgag tacaaagatt attatactac tggctataag acagatattg atactatcaa
     3781 cattaaagac aacaccattg attttgtagt caacggtgaa catcatcaat acacatacaa
     3841 atatgttgga tacaaaattt tgaattatga aaaaggaaac cgtggtgttc gttttaattt
     3901 tgaaactgat gatgcaggtg ctggtcgttt taaatatatt caatttagtg atcatggaat
     3961 tgcaccaagt aaggcagagc atttccatat tttctttggt ggagaaagtc aagaaaaact
     4021 ttataatgaa atgcataatt ggcctacttt ctatccagct tcattatctg agcatgagat
     4081 tgctcaagaa atgatggccc attaaaatcc aatctttgga gaaaatacat ggtaagaaaa
     4141 gtattattgt ctatggattc caagaatatt gatgcttatc ggcgttatcg atttgcaaag
     4201 caaatgagat taaatgggag tacattagct gatattgctg caactttaca tgttagtgtt
     4261 gatacagttc gtagagtgtt aaaacaagac cgggattgtt gttttatcaa ggtcaatact
     4321 ggaagaagta gacgtttagc aaaacgatat aatagtttga ttaattagtt gtaacagtag
     4381 agcagattaa ttttctttta ttaggatttg atctgctctt tattatgtat aggaattaac
     4441 atattcgaaa aaatattaca aaattgtaat gctattattt ataattaatt attttacaat
     4501 gctaaaattg atgataatat tttattgtat ctgttaataa aagttttt
//
LOCUS       DAKCAA010000120         4465 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000120 DAKCAA010000000
VERSION     DAKCAA010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.123"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            574..1008
                     /locus_tag="OUE31_002670"
     CDS             574..1008
                     /locus_tag="OUE31_002670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223625.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="OUE31_002671"
     CDS             2298..3221
                     /locus_tag="OUE31_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCU0223626.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="OUE31_002672"
     CDS             3237..3776
                     /locus_tag="OUE31_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCU0223627.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1669 a          674 c          756 g         1366 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacggagaa cttaaattaa attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagagacg gataaataat aaaaaagact
      181 gctctttcga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tatgaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacacccca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttga cttagaccaa tcgaaaatca caaagtgagc gtctctatcc attggtagag
      421 gggctacttg gcatactaca cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa ataaactgct tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct ctcaacgtgg taaaaatccc acttataaga gaaaatggtc aagaacctaa
     4261 acggtcggcg aagaaaacat accaagcacc acaagcaaaa aaagttagag taacttccaa
     4321 aaaagaaaaa ttttttagaa caacttttga aaatttaatt ttgatttata tccgttcaat
     4381 ttaaacattt gataaactga aggctagtat ttaaaatgtg tatacaagtg gtagcgttaa
     4441 aaaaagtgga ggtataacct atgtt
//
LOCUS       DAKCAA010000121         4435 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000121 DAKCAA010000000
VERSION     DAKCAA010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.124"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            90..1511
                     /gene="gndA"
                     /locus_tag="OUE31_002673"
     CDS             90..1511
                     /gene="gndA"
                     /locus_tag="OUE31_002673"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HCU0223628.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            1704..2390
                     /locus_tag="OUE31_002674"
     CDS             1704..2390
                     /locus_tag="OUE31_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCU0223629.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            2387..3892
                     /locus_tag="OUE31_002675"
     CDS             2387..3892
                     /locus_tag="OUE31_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCU0223630.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
BASE COUNT         1547 a          729 c          921 g         1238 t
ORIGIN      
        1 aaatatgttg ttctttagtt tgcaatgtag ccgtgttaag ctataatgta agagattagg
       61 gagaaatccc gtatgtagga ggagttcata tgtcaaaaca acaaatcggc gttgtcggta
      121 tggccgttat gggtaaaaat ctagccttga acatagaaag ccgcggctat tcagtggctt
      181 tattcaatcg tacaggggct aaaacaaccg ctgtagtaga agaacaccca gataaaaatt
      241 tcaaagcaac atatacaatc gaagaatttg tagaatctat cgagaaacca cgtcggatct
      301 tgctaatggt caaagcagga ccggcaacag atgcaacaat ccaagagtta cttcctcacc
      361 ttgataaagg cgatattttg attgacggag gaaatacatt ctttaaagat acgatgcgtc
      421 gtaatgaaga gttagccaac tctggcatca actttatcgg tacaggcgtt tccggtggtg
      481 aagaaggagc tttaaaagga ccttcaatca tgcctggtgg acaaaaagaa gcctatgcgc
      541 tagttgcacc aatcttagag caaatttctg caaaagcaga agacggagca ccatgtgtca
      601 catatattgg cccaaatgga gccggacatt atgtgaaaat ggtacacaac ggtattgagt
      661 atggagatat gcaactgatt gctgaatctt atgacttaat gaagaatatt ttaaaccttt
      721 cagtagaaga aatggctgat atctttaaag aatggaatca aggcgaatta gacagctatt
      781 tgatagaaat cactgctgac attctgacac gtaaagacga tgaaggaaca ggtaaaccag
      841 tagtagatgt gatccttgat gcagctggga ataaaggaac aggtaaatgg acaagccaaa
      901 gcgcgcttga cttaggtgtg ccacttccat tgatcactga atctgtattt gcccgctata
      961 tttctgctta taaagaagaa cgcgtacaag caagcaagat tttgtctcgt acgaacgatt
     1021 ttgagttcac gggagacaaa aaagaattgg tcgaaaaaat ccgagaagcg ttgtatttca
     1081 gtaaaatcat gagttatgcc caaggatttg ctcaattacg tgtcgcttca aaagaatttg
     1141 attgggactt gccatttggt gaaatcgcaa aaatctggcg cgctggatgt atcatccgag
     1201 ctcgattctt gcaaaaaatt acggatgcct atgacaaaaa tcctgagatc gaaaatttat
     1261 tgctagatga ttacttcgtt gaaatcacga aaaaatatca gcaatcagtc agagacgtcg
     1321 ttgccttggc tgtccaagct ggcgtacctg taccgacttt ctcatcagcc atcgcttact
     1381 tcgattcata cagagcagaa cgtctgcctg caaatataat ccaagcccaa cgcgattact
     1441 ttggcgcaca tacctatgaa cgtgtcgaca aagaaggaat cttccattac tcatggtacc
     1501 atgaagaata atagtctttc ggctgttagg aaatgagaaa ataaaaagag gacgaaagag
     1561 ctgaagtcga ttgttatgag tagacttcag ctctttttta aaattgctat ccatgataaa
     1621 atgactatag atttttaagc atattatcgg tataatgata gagtttttaa aaagccagta
     1681 gaatagaaag gataaaataa taaatgagca atattctaat cattgaagat gaaaagaact
     1741 tggcacgatt tgtcgagcta gagttgaagc atgaagggta taacgcagaa gtccactaca
     1801 acggccgaac tggtttagat gcggcattaa ataatgagtg ggatgccata ttgttggatc
     1861 tgatgctccc agaattgaac ggtttagaag tctgcagacg tgtacgccaa gtcaaaaata
     1921 caccaatcat tatgatgact gcaagagatt ctgtgatcga tcgtgtatct ggacttgacc
     1981 acggagcaga tgactacatc gtcaaaccat ttgctatcga agaattatta gcacgtcttc
     2041 gtgcattgtt gcgtcgaatc gatattgaag gcgataaaaa tgtggctaaa caaactacta
     2101 ttacttatcg cgatttgact atcgaaaaag aaaaccgtgt cgtacgtcgc ggaaatgaag
     2161 taattgaact aacaaaaaga gaatacgagt tgctgcttac tttaatggaa aacgtgaacg
     2221 tggtattagc acgtgacgtt ttactaaata aagtgtgggg atacgaaaca gaagttgaaa
     2281 caaacgtagt ggacgtatat attcgttatc ttcgcaacaa aattgacgtt cccggggagg
     2341 aaagctatat ccaaactgta cgcggaacag gttatgtgat gcgctcgtga taaagccgaa
     2401 aaaatcggaa aaaagagaac tgaaagggcc ctccttgaca atcaagtggg cctttgcgag
     2461 ttctttcttc atattcgttg tgtttacaat tttcgctgtc attacctata aatcatctat
     2521 caatctgatt gtggcaaaag aaagaaacaa tgtagagcgt acgatttcag aagtagcttc
     2581 tcgtttggct aactcggatg aagaactgac attagtaaat acgtatcgta atctgacgaa
     2641 agcgacaaat gacggagatg aggtcgtaga tcatacttca ctggtcgaag gaaacttaat
     2701 gaagatcgat tcctttatag ctgagctagg gcagccatca atggatcttt atgtttatga
     2761 tttggacgag aacttgattt ttaaaaccca tgaaaacagt cgaaacctga ttcagactac
     2821 acgtaaagtt ccaacgatcg ttacactaga aggaaaaact ggctttttat ctatccagcc
     2881 tatatattct aaaggtacaa gagaaaagat cggctatgcg caaagcttct atgaattatc
     2941 ttctttctat gatattcgaa ataagctatt attgactctt attgttttag aagttgtttc
     3001 tttgatctta agtagtattt taggtttctt tttatcttct tatttcttaa aaccactcaa
     3061 ggtactcaga gatacaatgg atactatacg taaagatccg caatcagata tccacatgcc
     3121 tgaaatcgac acaaatgatg aattggcaga tttagctgaa atattcaatg agatgcttga
     3181 ccgtatgcgt ttgtatattg aacaacaaga gcaattcgtg gaagacgtat ctcatgagtt
     3241 aaggacacct gttgcaatta ttgaagggca tcttagtctg ctaaatcgtt gggggaaaga
     3301 tgatcctgag atattagaag aatcattaag cgccagcatg caagaaatta gccgtatgaa
     3361 aagcttagtt caagagatgc tagacttatc aagagcagaa caagtagatg ttcattatgc
     3421 gaatgaaaca actaaaggaa aagaagtcac ctatcaagtt tataataatt tcaagatatt
     3481 atatccagac tatgtgatca ctttagatga tgatttgaca aaagaagtga ccctgcaaat
     3541 ttatcgtaat cactttgaac aattaatcat tatcatattg gataacgcag taaagtattc
     3601 aactacacga aaagaagtcc atatctctat ttcttccact ctgaatgaat ttgagatcgc
     3661 gattcaggac tttggcgaag gaatacccaa agaagacctt aataagatct tcaatcgttt
     3721 ttatcgagtg gataaagcaa gagctagaac gaagggtgga aatggtctgg ggttgtctat
     3781 cgctaaacaa ctggttgaaa actataaagg acgtatctta gcagaaagtg tagtagggca
     3841 agggacaatt tttagaatct ttattcctat cgcaaaggca gaagacaagt aaagcatgtg
     3901 ctttacttgt ttttttatat atccaacaaa gaataaggta caaaatacaa gcaagttaga
     3961 aattcaggga tgtcattata aaaaaaacta gcgaacaatt aaatagaata acatccgtta
     4021 attaaacgta agtagctttt agatgaacga aaaaacaatg aaatgctgta atattcgtgt
     4081 ttaaaaataa taaataaaaa tagggaattt tctattgcaa ttttataaag agattgctat
     4141 attattattt gttctaaatg attcctttaa ggtgtcacta aaaattataa aaaatagggt
     4201 tgacgcactt ttgatgtcat gttataataa cgaagtcgtt tggatgaggt agctaataaa
     4261 gcttgatttt atcgaaaaaa acttcgaaaa agttgttgac aaataacaat aaagatgata
     4321 tgataatcaa gtcgctgcta atgagtgaca aagacgttta gaaaaaataa acaaagaagt
     4381 tgttgacatt ctcttctgaa tctgataaga ttaaagagtt gttgaaacaa aaaga
//
LOCUS       DAKCAA010000122         4416 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000122 DAKCAA010000000
VERSION     DAKCAA010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.125"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            59..913
                     /locus_tag="OUE31_002676"
     CDS             59..913
                     /locus_tag="OUE31_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCU0223631.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="OUE31_002677"
     CDS             1010..3259
                     /locus_tag="OUE31_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCU0223632.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..>4416
                     /locus_tag="OUE31_002678"
     CDS             3262..>4416
                     /locus_tag="OUE31_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCU0223633.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          625 c          806 g         1429 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actaga
//
LOCUS       DAKCAA010000123         4129 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000123 DAKCAA010000000
VERSION     DAKCAA010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.126"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            148..1497
                     /locus_tag="OUE31_002679"
     CDS             148..1497
                     /locus_tag="OUE31_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0223634.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1625..2215)
                     /locus_tag="OUE31_002680"
     CDS             complement(1625..2215)
                     /locus_tag="OUE31_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCU0223635.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2362..3714
                     /gene="brnQ"
                     /locus_tag="OUE31_002681"
     CDS             2362..3714
                     /gene="brnQ"
                     /locus_tag="OUE31_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCU0223636.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1191 a          753 c          800 g         1385 t
ORIGIN      
        1 aaagagctgc ggtgtttacc gcagttcttt tttatgaatt actcataaaa ggtaaatttc
       61 tgaaaatttt ggaatcttag ttgtgttttt cagaaaactc tcttaatatg gaagtaatta
      121 aactttttta gttaggatga tttaaaaatg aatgaagagc aagaactgca gcgtggactg
      181 aaaaatagac atgtccaact gatttctatt ggcggagcga ttggaacggg gttgttttta
      241 ggttccggaa agtctatcca gctagctggc ccttcgatat tgctcgccta tcttattact
      301 ggatgcatct gttttttcat tatgcgtgcg ttaggcgaac ttctgttatc aaacaccaat
      361 aaccattctt ttctggattt tgttgcagaa tatcttggca aaaaagcggc tttcatcact
      421 ggctggacgt attggttctg ctgggtatcg attgcaatgg ccgatttaac agccatcgga
      481 atgtatgtac gctactgggc gcctggtgtt cctcagtggc ttcctgaact gattgcatta
      541 ggtcttcttc tttgcttgaa tatggtggct gtctcattgt ttggtgagtt agagttttgg
      601 tttgcattga tcaaagttgt agcgatcatt gcctttatcc tcgtaggagc ttatatgatc
      661 ctcacccact atacgacaga tattggcaca gccagtatca cgaatctatg gtctcatggc
      721 ggattctttc caactggtgc aaaaggattt atcttagctt tccaaatggt aacctttgct
      781 tttgctggga tagaattagt tggattagtc gctggagaaa cagaaaatcc tgaaaaagtg
      841 ttgccggaag ctatcaataa tattcctatc aggatcatct tattttactt aggatctctt
      901 tttgtcatta tggcaatcta tccatggaac agcttgaatc cagataacag tccatttgta
      961 gaagtatttt cggaaattgg gatcacgatt gctgcttcct tgatcaattt agtcgtatta
     1021 agtgcagcag cttctgcctg caacagtgca atatatagta caggacgtat gcttcgttct
     1081 ttagcgcaag aaggcagtgc ccctaaaaaa ttcaaaaagt taacaacaca tcatgtgcca
     1141 gggaatgctt tgacattttc tactatcgtc attttcattt ctgttatctt gaattacgtg
     1201 atgcctagtg aagtattcac actagtaagc agtattgcca ctacttgttt cttgtttatc
     1261 tggagtatgc ttgtctacac gcacatgaaa tatcgtaaaa gtatcctcgg caaaaaagct
     1321 cattcattta aaatgccgtt gtacccattt agtaattatc tggtatttct ttacatggcc
     1381 tttgtgtgtg tcgtcttgtt cctaggaaaa gatacgagaa tcgctttatt actaacacct
     1441 gtgtggttct tgcttctatt actaatctat catatgaaat atgaacgtaa gaagtaagaa
     1501 agtagttgtg acagaagtgg tcagcttcga gaaataagaa ggaatttacg aaaattgctt
     1561 cttaaatttt tgtgaaattt cggcttattt cttggagata aaagcttctg tcccagcctc
     1621 ttttctattt ccccggaaac aaccgctgat aataggcatc tgctttttta taggaaaaaa
     1681 tccaaatacc agatacaaaa aaacgtccga ataacccgat caacggtaca aaaaagacac
     1741 cggcaatcaa gcataagtta atcatcatgg agataagact tcgacggtcc tttgacaaaa
     1801 ctctcacgac atgggaatct ggtttatttg ctttcatgat ttgcctcatc aagataccaa
     1861 aagaaaaact ccacatcgtg tatactaaga cataagccat ctcaggccaa aaagcttcag
     1921 ggttacgccc gacccaacta gtaacagaag gacataaagt cagccaaaag agcaaaaaga
     1981 tattcgacca gaccactcgg taattaattc gttctgccat ctgaaatata cgatgatggt
     2041 tcacccagat caccgcaaca aatataaagc tgatggtata agctaataat gtatttcgga
     2101 tgacccataa agaatgaaag ctagatgtat tagggatctt gatctctaat acaataactc
     2161 tcaaaacaat ggctaccact ccatcagtaa atgcttctaa tctcgacttt gtcacgatga
     2221 ttcctcctca gatgattcag cgcttttatt ttatcactta cgttattaaa taaccatcgt
     2281 tttatatagg gaattttctg aaaattgttg catatttttc gaaattttgt tacttttaaa
     2341 aaaaccgtaa aggagttatg tatgacaaaa aaattatcat ttaaagacta tctttttata
     2401 ggctccatgc ttttcggtct attttttggt gctggaaatc ttatctttcc cgttcatttg
     2461 ggtcaagaag caggcgctgc taccttttgg gcgaatctag gtttcttggt taccggtatc
     2521 ggtcttccct tcttaggggt gattgccatt ggtgtatcga aaagctcagg tgtatatgaa
     2581 ttagcaaaac ggataaatca aacatatgcg atggttttta ccatcttgct ttacttagtt
     2641 atcggaccgt tttttgcttt acctcgcctt gcaaccacat ctttcgagat tggtttagca
     2701 ccatttatcg atcctagcag acagacgcta tatctagcaa ttttcagtat tgtatttttt
     2761 gtgctggctt ggtggttttc aagaaaaccg acaaagatat tagattatgt tggaaagttc
     2821 ctgaatcctg catttttggt tttattaggt gctttgcttc tccttgcttt tttgaatcca
     2881 ctaggttctg taaatcaagc gcctattcag ccaaattatc aagagcatgc ttttttcaca
     2941 gggtttactc aaggatataa cacattagat gcgcttgctg ctttagcatt tgggatcatc
     3001 attgtcacaa caatccaaaa catgggtgta acaaaacctg ctgaaatcgc taaagacacg
     3061 atcaaatctg gtgcgatcag cattatattg atgggaatca tttatacttt gctcgcttat
     3121 ttaggtgcta tgagcttagg tagctttgct ctaagtgaaa atggcgggat cacgctggct
     3181 cagattgctg atcattattt aggtacttat ggcagtatct tattagcatt tatcgttata
     3241 ttagcttgct tgaagaccgg tattggtttg attacagctt ttgcagaaac attcacagat
     3301 ttgtttccgc aaagaaatta cgcattcttt gttgcacttg ctagtatcct tccttgttta
     3361 gcggcaaacg taggcttgac gaatatcatt caattttcgt tgcctgtttt gatgttcatc
     3421 tatccattag caatgacact gattttacta gtgttagttg gtcctttgtt taagcagcgt
     3481 acggctgttt atcgaatgac tacttatttt acattgattg cttcgatttt tgatgggttg
     3541 aacgcttgcc cagaaactat caaacaaaca cctattgttc aaaatctttt atatgttgcg
     3601 gaaagctact tgccgttttt caaattgggg atggggtgga tcgtaccagc agttatcggt
     3661 tttgttatcg gactgatttg gagtttcgct aagaaagaag aagtagcaga ttgataaaag
     3721 aggttgtgaa agagacgttc agccttgagc aataaaaagt aattttgaaa aatggcttct
     3781 cacatttttg cataaatttg acttaatacc gagaaactga cttttgaaca ccgtttattg
     3841 agaggtcgtg aaaaagccgc ttagtttcaa gtattaagaa atattttgtg aaaatggctt
     3901 ctcacatttt tgcataaatt tgacttaata ccgagaaact ggcttttgaa caccgtttat
     3961 tgagcgtcta taaactgacc tgagtattag agaaacaaaa cggcaaagta gctccatata
     4021 ctttgccgtt ttgttttgaa ctaataccga agagaagctg atcaaacaac atttctttta
     4081 taatatagat tttagacata tatatgatat aaaaatagtt ttcgcaaaa
//
LOCUS       DAKCAA010000124         4033 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000124 DAKCAA010000000
VERSION     DAKCAA010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.127"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            177..773
                     /locus_tag="OUE31_002682"
     CDS             177..773
                     /locus_tag="OUE31_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCU0223637.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            897..2696
                     /locus_tag="OUE31_002683"
     CDS             897..2696
                     /locus_tag="OUE31_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCU0223638.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2974..3186)
                     /locus_tag="OUE31_002684"
     CDS             complement(2974..3186)
                     /locus_tag="OUE31_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223639.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3648..3797
                     /locus_tag="OUE31_002685"
     CDS             3648..3797
                     /locus_tag="OUE31_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223640.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
BASE COUNT         1185 a          689 c          711 g         1448 t
ORIGIN      
        1 taaaaaaaac aagttattaa ataagtcttt agttggatgt ttttttgaga tcaatctttt
       61 atacttatga tgaacttaca aaattgtttg ttttctgtca tatcaaaaaa tggcgcagtt
      121 agttgctttt ctagtaaagt atagttaaca aagaacctct aaggagttga tgaataatga
      181 atattgctgc ctctcgaaaa ctgataaatt tcatatccat tatcggatta ggcctatcaa
      241 tcgcgctgac gatttatttt attaatttag gtgttttcaa agatttgaat gcgttaagag
      301 gattagtagg tgattccatc attttaggac cgattatttt tgtcttcatc caaatcctgc
      361 aagtagttat tccaatcatt cctggaggga tcagtactgc agctggtgtc ctgatatttg
      421 gcccttatgc tggatttatc tataactata ttggaatctg cattggttcg attatcattt
      481 ttctgctagg gcgtcgttat ggaaagccat tcatactttc catgattagc gataagacat
      541 ataacaaata tattggctgg ctggataatc aaaaccgttt tgagaagctg tttgctctag
      601 ctatttttct tccagttgct cctgacgatg cgttatgttt gatggctgga ttgacaaaca
      661 tgtcagtgaa acgatataca ctaatcattt tgattgctaa accactgtcg attttcttat
      721 atagtatggc cttgatttat ggaggtcaat atctaagtgg tcttcttgga taatatttat
      781 tttgtaaaat tagtcattga ttgacaatgt taaatctggg aaagggtctg caaaacacac
      841 tgcacccttt cctttttcat tagatttgcg ctacaatgtg aagagcaggt gataggatga
      901 attatttgaa acgtagctta ggtaatgctt gggacttttt aaaaggaaca caagcttatt
      961 tccgtgatgt cttgctgatg catggcttta ttttatttat ttgtttaccc ttattgagca
     1021 gtacgacccg ttttatttta caccgagggg caattgacta tttgtcttat gacaatattc
     1081 cttcaatttt ttctcaacat cctggggttc tactctcgtt aatcgtagtt ttgatgacga
     1141 ttttactgtt agtttatttc gaatttactt ttcttttgat gagtgttttt tttattaaaa
     1201 agaaagaacc aatctctttg aagcaactct tacacttgac gatacttcag ctgaagaaag
     1261 tgagacccat tacttttttg tttttccttg cttatttttt attgattcta ccgatcagcg
     1321 gattaagttt taattctgat ctactgtcaa aaataaaaat ccccgctttc attatggatt
     1381 ttatttttgc taatcgttgg atcatcgtca gttccttttt actcgtttat attttccttg
     1441 gctatattgg gattcgactg atttttgctt taccggaaat gattctacga gatcgtcctt
     1501 ttcgagcagc cattcgggaa agctggtcat tgaccaaatc gcgtcttttg gccatcacgg
     1561 gccaatttat tgtgattggc ggtacgattt tactcctttc ttctttagga tatatcgttg
     1621 ttattttggc acaaagtatg gttgaacaat ttttcccaga ctatgcattg atcagcgctg
     1681 tgtttgctat gacgctttta caagggattt tattattcaa tatcgtgatg tctaccgtag
     1741 ggatttttta tatcattgtt gatttcatgg atgacgaagg cttcttgcct gagatcccta
     1801 agtggtttat cccacaagcc cccaacttgc gtttctctgc gctgaaaaac actggtttga
     1861 ctctttttgc agtttttttc ggtattggcg tctgtcttta caatatggat tatctgactt
     1921 cagctgttca gacaaaacca gtgactgtct ctcacagagg tgtgagtacc caaaatgggg
     1981 cgcaaaatac tttagaagca cttgaaaaaa caagcagaga ctatcatcct gattatgtag
     2041 agatggatgt tcaggaaaca aaagatggtc atttcgtagt gatgcatgat gcaaatcttc
     2101 gtcacttaac aggggtaaat ggaacaccac aggatcttac attgaaagaa ttgacaaatc
     2161 ttacagttac tgaaaacgga gtgcaagccc ctgtttgttc ttttgattct tatttggaaa
     2221 aagcacataa gctaaaccaa aaattactta ttgagatcaa gacctctaaa aaagattcgg
     2281 atgaccttgt cgaacgattt gtccataaat accgcaaagt tatcttagag aaccatcata
     2341 ttttgcaaag tttgacgtac caaaccgttt cagatttaaa agaagcagaa ccaaactttt
     2401 atgtgggcta catcttacct ttcaatattg ttgggccccc tgtgacgcct gctgattttc
     2461 tgacaatgga atatagtacg atcaaccgta acttcattaa ttctgcccac caagacggaa
     2521 aagaagtata tgtatggaca atcaacgatt cagatgctat gagtcgcatg atgttttatg
     2581 gtgtggatgg tatcataacc gatgagatgg gactactaaa tgaaagtgtg aaacaaacag
     2641 atgaagaaat cacttattca gataaactgc taaattttgt tttgggagtc ggctaatcaa
     2701 aaatcgttaa tgaaaaaagt ctttatacaa caaaaaacgc ataacctgcc accgcaggta
     2761 tatgcgtttt ttgtttgacg ctcataatgt gtgcttaact ttctcttgat tccttcatcg
     2821 cacgaacaat agctaaaata gcaggaattg cagagatcac tgcaagaata attcccattt
     2881 tccctgaact ttttcttttt ggcatatctt ctcgctccct tctgtcttta tttatattat
     2941 aagggagttc ttgcgaattc tcaaaaatac tgtttaagaa accaattcag caggtgcgct
     3001 aatatcacag aattttacga gcatgcgata cttgctttca ttgataagtt gatagtctcg
     3061 ttggtcataa ctttcaacat acacgacagc cgtgttgata tatgtacgtt caatacagcc
     3121 gattagttca tgagatactc cgatcggttt gcatatataa gatcttccta cttctgcttt
     3181 taccatttca ttccctcttt tctttatttt tattttgttt tttctttatt ttataataac
     3241 aaattacctt gtatttgaaa acgtttttat ccattttttt attttttatt ttgagtatct
     3301 ttctgctttt tagataacta ttttttaaca cgatcttaga cgttgtgaca aaaacgtttg
     3361 tttatattcc tatgttgttc gtgcgttttt ttctttatat tgctaagtta tttataaaga
     3421 ggtgagcata tgatttatat tcaagcaata gtatttgtaa ccttgatgat tgggctactt
     3481 atcggattaa aagaaaatag ctaaaccatt taagaaaaaa taaataagga aaatgataaa
     3541 tgctttttaa ttgcatcaaa aaacgtacga tgctaaactt ggtataagtt cgaaagttta
     3601 aaggaaactt tcaagaacta aattacatta caaaggagat gaattttatg acgtttacaa
     3661 aaacaaatat gcaataccgc gtagcttttg atacaacttc taaccgtttt atggcgattg
     3721 atgcacaaaa cgaaaataac gttgcgtttg gtattacaat cgaacaagca gtccgagcat
     3781 taaacgaatc tagataagga gtgaaccatt ccaaatggcg actgatgaga tctcggaaaa
     3841 tcaataaaag acgtttgtaa cggtaatccg cgacaaacgt ctttttgtat tcattacata
     3901 tatttggaaa ttgtctctct ttatctctag acctaaacaa aaacacaagt tctaatatca
     3961 accatctcgt tttttatgac aattttgtta gctgtttcga tgataatatt ccgttattat
     4021 ctgtataata ttt
//
LOCUS       DAKCAA010000125         4004 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000125 DAKCAA010000000
VERSION     DAKCAA010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.128"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            226..330
                     /locus_tag="OUE31_002686"
     CDS             226..330
                     /locus_tag="OUE31_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCU0223641.1"
                     /translation="MELPKTGEKYNGLPVYVGLFTAIASIIGLKKNKF"
     gene            778..1497
                     /locus_tag="OUE31_002687"
     CDS             778..1497
                     /locus_tag="OUE31_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCU0223642.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLISERIIMDTLKELKNQGKTVLIVHHDLSKVKKYFDNIILLNRNVIAHGSVES
                     VFNEENLKKAYGDTIFIGERE"
     gene            1499..2341
                     /locus_tag="OUE31_002688"
     CDS             1499..2341
                     /locus_tag="OUE31_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCU0223643.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAMGMNVNFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISAAVGASSSLLGLFIGYNFNIAAGSSIVLTAASLFVISFLISPKQKFLRKK
                     ERSL"
     gene            2341..3282
                     /locus_tag="OUE31_002689"
     CDS             2341..3282
                     /locus_tag="OUE31_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCU0223644.1"
                     /translation="MRKWKVVVGSLGILIALFILGACSTNSKDKVASNEKLKVVVTNS
                     ILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGGNA
                     WFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNIEK
                     HLAEKDPDNKKIYKENLDKYIEKLNTLDKEAKSKFASIPNDKKMIVTSEGCFKYFSKA
                     YNVPSAYIWEINTEEEGTPDQIKHLVERLRTTKVPSLFVESSVDDRPMKTVSKDTNIP
                     IYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            3300..3531
                     /locus_tag="OUE31_002690"
                     /pseudo
     CDS             3300..3531
                     /locus_tag="OUE31_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
BASE COUNT         1485 a          480 c          723 g         1316 t
ORIGIN      
        1 gatcttggtg gagaaaaaga gaaagacata gcagtcaaat tacccggagt aacgaaaaat
       61 acaaattcta aacaaagttc ggatagtaaa gctagcttta atcatccttc tacttttttt
      121 aacaacaaca aaagatcatc taatctaaat tataataata gcaataaaaa aagggaacta
      181 atgaatcaag aaaaaaataa agaaggcaat cgaaataaaa atactatgga gttaccgaaa
      241 actggagaaa aatataatgg tcttcctgtg tatgtagggt tattcacggc gattgcaagt
      301 attatagggc tgaaaaaaaa taaattttaa tgtgggaatt attattattt ctctaattct
      361 atttgagcaa tttaaaatat gaaaatcaat aaagagaaag ttttaagttg ttaagtaaat
      421 taaatttcga ttggaagcat agttgaataa gcctaacatg ttacgaaaga taaataacct
      481 acttttcatt tctagaagag aatgtcttga tgcttataaa cagatttagc tccctatcca
      541 cttcaagtct aattcttttg tatgcaaata aagtattttt aggagagtgt tctcattaga
      601 gaacactctt tttttgtttt gaaaactact tactatacgg gtagtttcaa atagttttgt
      661 catcctaatc ttcagcaaca gaaaaaaatc caaattttaa aatttaggct tgactaaaat
      721 atattttctg tataccatat aatcgtgata atcattatca tttagaagga gaaagttatg
      781 ttagaagtga aaaagcttaa tgtttgttat aacgattttt tagcattgaa cgagatttct
      841 ttaaaaatac aagaaggtgc tctaacaggt attattggtc caaatggtgc tggaaaatct
      901 acattactta aagcaatgtt aaatattatc cctcatcagg gagaggtctc cattaataat
      961 gaagatatca ataaaaaact ggtaaagatt gcatatgtag agcaaaaagc tgatattgat
     1021 tttacttttc caataaaagt aaaagaatgt gtatctatgg gaacgtatgc cggaatgaaa
     1081 gtttttcaaa gaattaaaaa tgcagaatgg caaagagttt caaaggcttt ggaaaaggtc
     1141 gatatgggaa aatattctaa tcatcaaata ggagaattat ctggaggaca atttcaacgt
     1201 gtacttttag caagatgtct tgctcaaaat gcggatttca tatttttaga tgaaccattt
     1261 gtagggatag acttaattag tgaacgaata attatggata cgttaaaaga attgaaaaat
     1321 cagggaaaaa cagtgctaat tgtgcatcat gatttaagca aggtaaagaa gtattttgat
     1381 aatattattc ttttgaatcg aaatgtaatt gctcacggaa gtgtagaatc tgtatttaat
     1441 gaagagaatt taaaaaaagc ctatggagat actatattta ttggagagag ggaataacat
     1501 gcttcaaaat tttattaatg gtctgtatga ctttcacttt ttacagaatg ctctaattac
     1561 atctgtagtt atagggattg tttctggaac agtaggttgt tttattattt taagaggaat
     1621 gtctcttatg ggcgatgcta tttctcatgc tgttttgcca ggagtagcaa tttcttatat
     1681 tttaggtatt aattttttta ttggtgctat tgtatttggt ctattagctt ctatcattat
     1741 tacttttata aaaagcaata gtgtaataaa aggagataca gcaattggta ttactttcag
     1801 ttctttttta gcgctaggag ttatccttat aggagttgca aatagctcaa cggatttatt
     1861 tcatatctta tttggaaaca ttttagctgt acaagatatt gataagtgga ttacgattgg
     1921 cgtttctgtt ttagtgttgg ttatagtagt tctatttttt aaagaattat taattacttc
     1981 ttttgatcca ttaatggcaa aagcaatggg gatgaacgtc aatttttatc attatctact
     2041 gatggttcta ttaactttag tagcagtaac agctatgcaa agtgtgggga ctatattaat
     2101 tgttgcaatg ttaatcacgc cagcagctac agcatattta tatgcaaata gcttgaaaac
     2161 tatgatattt atttctgcag cagtcggggc aagctcatca ttgcttggat tgtttattgg
     2221 ttataatttt aacatagccg caggatcaag tattgtttta acagcggcat ccttatttgt
     2281 aattagtttt ctaatctcac caaaacaaaa atttttaaga aagaaggaga gatcgttatg
     2341 atgagaaaat ggaaagtagt agtgggaagt ctggggattt tgattgctct ttttatatta
     2401 ggagcgtgtt caacaaatag taaagataaa gtggcttcga acgaaaaatt aaaagtagta
     2461 gttactaatt cgattttagc agatattact gaaaatatag caaaggataa aattgattta
     2521 cacagtattg tacctattgg gaaagatccc catgaatatg aacctttgcc tgaagatgtt
     2581 caaaaaactt caaaagcaga cttgattttt tataatggtg ttaacttgga aactggagga
     2641 aatgcttggt ttacaaaatt agttaaaaat gcgaacaaag aggaaaacaa agactatttt
     2701 gcagcaagtg atggcataga tgttatttac ttagagggtc agagtgagaa agggaaggaa
     2761 gatcctcatg cttggttaaa tttagaaaac ggtattattt acgctaaaaa cattgaaaaa
     2821 catttagcgg aaaaagatcc tgataataaa aaaatctata aagaaaatct agataagtat
     2881 attgaaaaat tgaatacact agacaaagaa gcaaaatcta aatttgcttc aattccgaat
     2941 gataaaaaaa tgattgttac aagtgaagga tgctttaagt atttctcgaa agcgtataat
     3001 gtgccttctg cttacatttg ggaaatcaac actgaagaag aaggaacgcc agatcaaatt
     3061 aaacacttag ttgaaagact acgcacaaca aaagttcctt ccttatttgt agaaagcagt
     3121 gtggacgata gaccgatgaa aacagtatcg aaagatacca atattcctat ctattcaacg
     3181 atttttactg attcaattgc agagaaagga caagatggtg atagttacta cgcgatgatg
     3241 aaatggaacc tggataaaat tgctgaaggt ctttcaaaat aaattggagg aaaaagagta
     3301 tggtaaaaat taaaccaact actatactga tttatttatt agcaattcag gaattgacga
     3361 aaagaaaaaa agttaaaaaa taaagattta gcaaaaattc taagcattac tccagcatct
     3421 gtaagtgaga tgttggctaa acttagatat gaaggttatt taaacatagg gtgtcaattg
     3481 acaaatagag ggaaagactt tattgacaat tacaaaaaga gctttatata aaagactttt
     3541 tatttagaaa ggataagaaa atgactattg gagtaattat gataggactt atcctaatag
     3601 ctggatataa tttttttaaa tctttcttgg attattttag aaaaggcgaa tgatttagat
     3661 gagtatatta cttcttatag gattactttt ttaatcagct attctgttgc tgctcattag
     3721 tttaggttta agcaatgagt ttaataatag acattaatgt ttaaaaattt atagaattaa
     3781 aaatatcata taaggcgaat tttctcatat agactaggta ctacgtgcca cttactgaaa
     3841 gataatagaa aatgaactaa gttattttca aaaggatgta cttcatcaaa ttaagatagc
     3901 tttgtttgtc tgaacaatct atctaaaaaa gataagttct atcgagatga taggataggc
     3961 ttataattag cctataaatt tttggaatac agctacaatt cttt
//
LOCUS       DAKCAA010000126         3940 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000126 DAKCAA010000000
VERSION     DAKCAA010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.129"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(323..544)
                     /locus_tag="OUE31_002691"
     CDS             complement(323..544)
                     /locus_tag="OUE31_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223645.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(642..887)
                     /locus_tag="OUE31_002692"
     CDS             complement(642..887)
                     /locus_tag="OUE31_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223646.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1127..1741
                     /locus_tag="OUE31_002693"
                     /pseudo
     CDS             1127..1741
                     /locus_tag="OUE31_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2111..3112)
                     /locus_tag="OUE31_002694"
     CDS             complement(2111..3112)
                     /locus_tag="OUE31_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HCU0223647.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3271..3537)
                     /locus_tag="OUE31_002695"
     CDS             complement(3271..3537)
                     /locus_tag="OUE31_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0223648.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(3527..3883)
                     /locus_tag="OUE31_002696"
     CDS             complement(3527..3883)
                     /locus_tag="OUE31_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCU0223649.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1242 a          714 c          520 g         1464 t
ORIGIN      
        1 ttactctgtc ctctctgtct tttttctcaa ttttacacta aaatagattt tttggaaaac
       61 tttgcaacag aaccgttttt actatatact tcttcccaga acttgtccgt ctccttcaaa
      121 ttatctctac ctctcgagtt cattgggtgg tttgcccatt tattaaacat ggaatcacct
      181 ttctcatact catatattta tgtcctattt caattatatt tatatatgct taaataaatt
      241 tgtatcctga aatttattgt aatatgaagc tgtattttac atatagtaac caaagagtta
      301 ataaaataaa aagagcgaac cattatagat cagctctttt ttcattgctg tttttaatct
      361 tatctagaat cacttcaaat gtttcaaagg tatttacatc taactgacat aaccaaagca
      421 agtacttctt ttctttgtaa gtccaatcaa tattacggta agaggacatt agattatggt
      481 accttgctct ttgttcaact gaagccaatt cccagcgttt ttcaaatatt ttttcttctt
      541 ccattattga tccctcgcaa gacgctacct caaacttaaa taatgggcag cgaaagtcta
      601 attccttaga tctaagtata gcaaacaaat atgaaaaaaa cttagaaggt agtaaaagtt
      661 cttccgtctt ttgctttgct tctattctta atgtgtttcg ttatcggtgc cctacaaaga
      721 ttttcattaa ttacacactc atttattgtt gtgtattttc tgacatttct ctcttgatca
      781 attattttaa ttccatgggc atcctgatag ttcataggag aggagcggct atcagaaata
      841 gttgcaccta tctcttgaac ttcttttaca acttctggaa aatccatcca tcctgcttca
      901 gctgtcaaaa gtaataatct ataatattta tctttccttt tcaatctaag aaatcgtcac
      961 cccattcttt ttcttctatt ataaactatt taacttttag aattcaaaaa ccgtttgtct
     1021 atttagagtt taccctaaat agacaaaaat ataacattga aaaatttaga gttctaacgt
     1081 atgattaggg tgtattataa acgttataga aaagtaggga ataaatttga aaattgctta
     1141 tattagagtt tcatccatcg atcaaaatga acaacgtcaa attgaagaaa tgaaaaagtt
     1201 tggcgctgaa aaaattttta tcgaaaaaca atctggagcg acgattagtc atcggccgat
     1261 tttccaggaa gctttagatt ttgtcagaga gcaagatatt tttattgtag aagccattga
     1321 tcgacttgga cgcaattatg acgagattat cgattcagtg aattatctaa agaagaagaa
     1381 tgtgcgactt attatcacca gtttaccgat catggctgaa gcaattggaa atcctctcct
     1441 agataaattc atcaaagact taatcattta aatctcagcc atgattgctg aacaagaacg
     1501 tactgaatcg aaacgacgcc aggcacaagg aattaaaatc gctaaagcaa acggcgtcta
     1561 taaaggtcgt cctaagttat acagtgcaga caccaaagat cctcaacgtc gccttgtcta
     1621 taggagtatc gttcaggatc ttgagaatgg ggttgctatc tcaaagattg caacagacta
     1681 caatgtgact aggcaaacaa tttaccgaat aaaaaaagaa atcgaccaac taattgtatg
     1741 atttcttttt tgaatcacgt aattattaat tagctttgtc atcaatacag acaatcattt
     1801 tagattcatc tagctaagtt gattacattt atgttaaaaa gaatttagtt aacataaata
     1861 taattgatgc ataaatcgtc cttatttaaa ggcatttaac attgacaact tagtataatg
     1921 tatcttatgt aaactaataa gatttgaatt ttattttata cacactcgat aatagatcaa
     1981 ttttatggtc ccccgcattt acgattgcac aagagaaaca taaagtcgac ctattagcat
     2041 ttcttttcaa ttcaaacatt aaaaaagttt atacctctgc tactaaaaaa tgaaattatc
     2101 tatttaaaat ttaaaacggt aaatctgatt catccaaatt ggaaaatgga tcagcctgta
     2161 ttggagcttt gtatttctcc ataataacag atatcttttt ttcatttttt aaaaaatacc
     2221 ttttaaattt cttatagtcc tctgaaatca aaatatagcg tgatggatac tcatcaaaag
     2281 aagaatcgta ttcttccttt aaaattcccg atttacttaa tttttctagt acatcaaata
     2341 ctctatcact caagtaactc cttaaattgt tatcactttc ccattgaact acttttctat
     2401 aagttgaatt atcagttgaa aagatagaat tttcatccat aaacgcatat attagcagca
     2461 atctttcatc attgtcaaat tctattggat caaaaatatc taagttgtca tcaaaatctt
     2521 tatcagttcc ggtaactttt ttgttaatta ctgaaggtgt cttgtaagaa atagaatcta
     2581 aatcaaagcg ttttgattct aaattatttt gtgctttctc aattaaataa ttcacttttt
     2641 ttgtgagaaa ccttctgata ttgtctttgc tatatgttcc ataaaaaccc ttatcttcta
     2701 aagagtccct gtacttctta acttctatat actcttcagc caaaacttgt ggaactggtt
     2761 catctaagaa aaaaacccct acctcgcctt tgctattttt ataaaagtaa tcaatttctg
     2821 ctatagttcc cgatctataa ttatcaactg gagaacccaa cttatggcca aaaatcgcta
     2881 ataatatatc actattttct acaatttgtt tattaataac actttgccca gagctattat
     2941 ttatataagt aggaatcgca ttcgtttccc atcgaattgg catcaaaatt acttttgtat
     3001 tatctgtatt ttctatattc catctatata tggtttcttc tacttcattc ctctttgctg
     3061 ctatatcacc tggtgatgct ataaatactt ttattagatt tatggttttc atttattgta
     3121 cctttctctt tatgtctctt taaagtaatt tttgtataaa atttattgac ttttacacta
     3181 taggacaact tttatctatt tagtacaaaa aggcccacta aactaattga ttagttagga
     3241 gcctattaca ggtatatttt caactcgctt ttaagcaaat tctactacca gctttttgcc
     3301 taatgcccta gcgatatcat caagtttatc gaaagatacg ttatcccctc tctcaattcg
     3361 agcaatagta gattgagttg tatgtgcttt ttgtgcaagc tccgcttgag ttaggcctgc
     3421 ttcctcccgt gcatgataaa gagcaaccgc agtttcgagt tttcttcctt cacggtcata
     3481 tgcttctgca aaatctttgt ctttttgctt ttcttcaatc aattttttaa tcatcatttg
     3541 tgaaccactc ctctctaagt tcttttgcat gtttaagttc acttattggt gttttctccg
     3601 tttttttagt aaatccatgg gtaatgacat accttccatt gaccacatgg aaatagatag
     3661 ctctttggat gtttgatcct accttacttc ttaattcgta caaattagtg tctaattttt
     3721 tcacccattt caaccgttga gctactagca tcccattctt ttctgtttct tctattgtac
     3781 gtaaaagctt cgcactatct ttttttggta atgtttccaa ccattctaaa aattcatcat
     3841 gaccattagg tcttttaaat gtttcaaaag atattttttc catacccaat tatatcatat
     3901 attgatttta tattatagta tataacataa aaattcgaat
//
LOCUS       DAKCAA010000127         3909 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000127 DAKCAA010000000
VERSION     DAKCAA010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.130"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            117..3149
                     /locus_tag="OUE31_002697"
     CDS             117..3149
                     /locus_tag="OUE31_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HCU0223650.1"
                     /translation="MVENKEIRFEQDIETSLTTYGKWKKETFNESNFDPIIGLDCQKL
                     LGFVQKTQPKQWARHQRNYNNDGEVKFLQRFNQEVETHGMLHVLRNGIKDRGVRFKVA
                     YFKPASELNDETMEKYEANSFTCTRQFAYSPNNHKTIDMVLSLNGIPLVALELKNQYT
                     GQTVENAKLQFQKDRDPKELVFRFNRRFLVYFAVDHTDVYMTTKLDGKKTYFLPFNQG
                     SNGPGRVGGAGNPSNKDGYPTAYLWEKVLTRDNLMDIIQRFMNLEIKKEKQGDREVTK
                     KTLIFPRYHQLDVVRKLVADVKSHGSGENYLIQHSAGSGKSNSIAWLAYHLASIHDQL
                     NYPIFSSIIIVTDRTVLDRQLQNTIMNFDHQTGLVETIDDRKSSQDLKEAINDGRKII
                     ITTLQKFPVIYQEVDQVEGRNFAVIVDEAHSSQTGNSAQKLKAALSDKSKSLEEYYEL
                     EGEVDDVLPDAEDELVQQLVAQGKHQNLSFFAFTATPKEKTLEMFGTKQPDGHFEPFH
                     VYSMRQAIEEGFILDVLKNYMTYSTSYKIAREIEDNPELPKSEATRAIVRFQSLHPWA
                     VTQKTAVMVEQFRAVTRTAIGGQAKAMVVTASRLHAVRYMKEFKKYIANKGYNDLDVL
                     VAFSGSVVDGETEYTETKMNVTKSGENVRENQLKEAFHTDNFNILIVAEKYQTGFDEP
                     LLHTMFVDKKLKGVKAVQTLSRLNRTMPGKKDTFILDFVNDVEDIEAAFQPFYEQTNL
                     REEINVNLIYDTQSKLRKFNVYNQGDIERVMKLVKQAQKQQNERLLGRISSMFKPIMD
                     RYEEMNKDNQYQFRVTLRNFGKWYDYISQLDRLFDMELLEERIFTGYLLKFLPKETRE
                     NIDISDKVKLEYYKLRQDFSGEIHLVNKEGELVNPKSIDAGIKPPDERDSLEEIIHKI
                     NERFPNDFDEGDRVLVEILYRSFADNPDLKVVSMAKNNDAQMFEKSLFPDVFKDKVME
                     QYEKNNAAFEKMFGHDDKYFDLVYTLVARDLYKLLRTK"
     gene            3339..>3909
                     /locus_tag="OUE31_002698"
     CDS             3339..>3909
                     /locus_tag="OUE31_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HCU0223651.1"
                     /translation="MSTTIEVNKQSVKQFLETGKIKKFVIPEYQRPYAWTDEQNQVLF
                     DDLAEYTANNNESTYFLGSIVAYENDHNEQEIIDGQQRITTLFLFLRAIYAKLENSCE
                     KEALFLKSQIEPALWEQDDLTGEVKPDKILIMSRVMGDEGNEEFASILVSGEADVKSK
                     SNYSKNYILIQHLLNEYATNEPLSFYRFIS"
BASE COUNT         1343 a          622 c          827 g         1117 t
ORIGIN      
        1 taataaatca aatgattgat aataagatag ctgaattgat ggaacttgag agttataaaa
       61 aagctctcat ctacgaatac gtaaccggta aaaaagaagc ctaggaggtg attcatttgg
      121 tagagaacaa agaaattcgt tttgagcagg atattgagac ttcactgact acgtatggca
      181 aatggaagaa agaaacattc aatgaatcaa actttgatcc cataattggt ttggattgtc
      241 aaaaattgct aggctttgtc cagaagactc aaccaaaaca gtgggcacgt caccaacgaa
      301 actataacaa tgatggagaa gtcaagttcc ttcaacgctt taatcaagag gtagaaaccc
      361 acggcatgtt acatgtattg cgcaatggga tcaaagaccg cggtgtgcgc tttaaagtag
      421 cttacttcaa acctgcttca gagctgaatg atgaaacgat ggaaaagtat gaagcaaata
      481 gttttacctg tactcgccag tttgcttaca gtcctaataa ccataaaacc attgatatgg
      541 ttttgtcgtt aaatggtatt ccgctcgttg ctttagaatt gaaaaaccag tacactggtc
      601 aaacagtaga aaatgccaaa ctccagtttc aaaaagatcg tgatccaaaa gaattggtat
      661 ttcgttttaa tcgccgcttc ttagtctatt ttgcggtgga ccatacagat gtttatatga
      721 cgacaaagtt ggacggtaaa aaaacgtact tcttgccatt caatcaaggt tccaatgggc
      781 cgggaagagt tggtggagca ggcaatccgt ccaataaaga tggctaccca actgcctact
      841 tgtgggaaaa ggtgcttact agagacaatt tgatggatat tatccaacgt tttatgaatc
      901 tagagattaa aaaagaaaag caaggcgaca gagaagtcac aaagaaaacg ttgatttttc
      961 ctcgttatca tcagttagat gtggttcgaa aattggttgc agatgtaaaa agccatggta
     1021 gtggagaaaa ttatttgatc cagcatagtg ctggttctgg aaaatctaat agtattgcat
     1081 ggctggcata ccatttagcc tctattcatg atcaactgaa ctacccaatt ttttcatcaa
     1141 ttattattgt gactgatcga acagtgttgg atcgccagtt gcaaaatact atcatgaact
     1201 ttgatcatca gacaggtttg gtagaaacga ttgacgatcg caaatcctct caagatttaa
     1261 aagaagccat taatgatggg cgtaagatca ttattaccac tttgcaaaag ttcccagtga
     1321 tctatcagga agtagatcaa gtggaaggtc gtaattttgc tgtgattgtg gatgaggcac
     1381 attcttcaca aactgggaac agtgcccaga agctaaaagc cgctctttcg gacaaatcta
     1441 aatccttgga agagtattat gaactggaag gcgaagttga cgatgtatta ccagatgctg
     1501 aagatgaact agttcaacaa ttggtagcac aaggtaaaca tcaaaattta agtttctttg
     1561 cttttaccgc tacaccgaaa gaaaagacat tggaaatgtt tggtacgaaa caaccagatg
     1621 ggcatttcga accctttcat gtttactcga tgcgccaggc gattgaggaa ggctttatct
     1681 tagatgtgct gaagaactat atgacctata gtacttccta caaaattgcc cgtgaaattg
     1741 aagataaccc agaattacca aagagtgaag caacccgagc gattgttcgt ttccaatcat
     1801 tgcatccttg ggcagttact caaaagacgg ctgtgatggt tgagcaattc cgagcggtta
     1861 ctcgtacagc tattggtggg caggcaaaag caatggtcgt taccgcatca cgcttacacg
     1921 ctgttcgcta tatgaaagaa tttaaaaaat atatagcgaa caaaggttat aatgacttgg
     1981 atgtgttggt tgctttttct ggttcggtag tagatggaga gactgaatat acagaaacga
     2041 agatgaatgt cacaaaatct ggtgagaatg ttcgggagaa tcaattaaag gaagctttcc
     2101 atacagataa ttttaatatc ttgattgttg ctgaaaaata tcaaacgggt tttgatgaac
     2161 cgttgctgca taccatgttt gtcgataaga agttaaaggg tgttaaagct gttcagactt
     2221 tatcacgact caatcgaaca atgcctggga agaaggatac ctttattctt gattttgtaa
     2281 atgatgttga agatattgaa gctgctttcc aaccctttta tgaacaaaca aatttgagag
     2341 aagaaatcaa tgttaacttg atttatgata ctcaaagcaa gctacgaaaa tttaatgttt
     2401 acaatcaagg tgatattgaa cgtgtcatga aattggtgaa acaagcccaa aagcaacaga
     2461 atgagcgctt gcttggacga atttctagca tgtttaagcc gattatggat cgctatgagg
     2521 aaatgaacaa ggataatcag taccagtttc gggtgactct acgtaacttt ggcaagtggt
     2581 atgattatat ttcacaactt gatcggttat tcgatatgga actattggag gaacgaattt
     2641 ttactggata cttgctgaag tttctaccta aagaaacacg agaaaatatt gatatttctg
     2701 acaaagtaaa gttggaatat tataagttac gtcaggactt ttccggtgaa atccatctag
     2761 tgaataaaga aggcgagcta gtaaatccaa agtcaattga tgcaggaatc aaaccgccgg
     2821 atgaacgaga ttcactagaa gaaatcattc ataaaatcaa tgaacgattt ccaaatgatt
     2881 ttgacgaagg agaccgggtg ttagtagaga ttttgtatcg gtcatttgcc gataacccag
     2941 atttgaaggt tgtcagcatg gctaagaata acgatgctca gatgtttgaa aaatcgctgt
     3001 tccctgatgt atttaaagat aaggtgatgg agcagtacga gaagaacaat gcagcttttg
     3061 agaaaatgtt tgggcatgat gataagtact ttgatctagt atatacatta gttgctagag
     3121 atttatacaa gttattacgg acgaaataaa atttataaat aaggattaga caatacaatt
     3181 tctctcaaaa ataaaggaga agttgtattg tttgctttta agaaagccct gaaaaatttg
     3241 ttacgtacta aattgtctga actctgtcat atcagctatg tcagaataaa ggaaatagat
     3301 ttatttttat aaacagtgtc gtctcggaga tttaaactat gtcaacgaca attgaagtga
     3361 acaaacaaag cgtgaagcag tttcttgaaa cagggaaaat caaaaaattc gttattccag
     3421 aatatcaacg tccttatgcc tggactgacg agcaaaacca agtactattt gatgatttag
     3481 cggagtacac agcaaacaat aacgagagta cttacttttt aggaagcatt gtggcttatg
     3541 aaaatgatca taacgagcaa gaaatcattg atggacagca aaggataact acgctatttt
     3601 tatttttgag agctatctat gctaaattag aaaatagttg tgaaaaggaa gctttattct
     3661 tgaaaagcca aattgaaccc gcgttatggg aacaagatga tttaacaggt gaggttaaac
     3721 cagataaaat tctgattatg tctcgagtaa tgggggatga ggggaatgaa gaatttgcta
     3781 gtattctagt aagtggtgaa gcagatgtta aatcaaaaag taattattcg aagaactata
     3841 ttttaattca acatctatta aatgagtatg caacaaacga accactatca ttttatcgtt
     3901 ttatcagta
//
LOCUS       DAKCAA010000128         3905 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000128 DAKCAA010000000
VERSION     DAKCAA010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.131"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(70..365)
                     /locus_tag="OUE31_002699"
                     /pseudo
     CDS             complement(70..365)
                     /locus_tag="OUE31_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(625..1173)
                     /locus_tag="OUE31_002700"
     CDS             complement(625..1173)
                     /locus_tag="OUE31_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223652.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1174..2031)
                     /locus_tag="OUE31_002701"
     CDS             complement(1174..2031)
                     /locus_tag="OUE31_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCU0223653.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2317..2603)
                     /locus_tag="OUE31_002702"
                     /pseudo
     CDS             complement(2317..2603)
                     /locus_tag="OUE31_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2593..2922)
                     /locus_tag="OUE31_002703"
     CDS             complement(2593..2922)
                     /locus_tag="OUE31_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCU0223654.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2999..3271)
                     /locus_tag="OUE31_002704"
     CDS             complement(2999..3271)
                     /locus_tag="OUE31_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCU0223655.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3271..3534)
                     /locus_tag="OUE31_002705"
     CDS             complement(3271..3534)
                     /locus_tag="OUE31_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCU0223656.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            3768..>3905
                     /locus_tag="OUE31_002706"
     CDS             3768..>3905
                     /locus_tag="OUE31_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCU0223657.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
BASE COUNT         1168 a          784 c          502 g         1451 t
ORIGIN      
        1 tgtcctctct gtcttttttc tcaattttac actaaaatag attttttgga aaactttgca
       61 acagaaccct tgatctcgct tattacaatc gctttcattt gtcctaagag tcaaatcttt
      121 ttccaccata acttttacac ccaataaatt ttgcggttta tttttctctg ttgaaattct
      181 ttgtgtagcc tttaaactga caattagctc attgggtaca tacttatttg agagtcatct
      241 aattggctca taatcctttc tttttggtta gtatctgcag ttacttgttt agtatgagcc
      301 atgaacccaa acatactcac cccaacaacc aatcctaaat atattttctt tttaaacttt
      361 ttcacctaca tctcctccta atagttttat tttagagtta gctctattac ttatttacta
      421 actcaacaac agattatcat acacttgtta atgaaatcac aatatctcat taaaacacac
      481 cctaaaatca taaccgttcc tatgctcatt ttttggattt tttaatcacg taaccagaaa
      541 aataaatccc ctctatttca tgcaaatcaa agaagaacta agtaactacc gtttaaaggt
      601 agttacttag ttcttctttg attattatct aactttatta ttcattcccc accctttgcg
      661 cagtgagtct tcggtatctt gttttatctg actggtagtt cttattattt ctccacgatc
      721 atctaattct ggaacaattg gatatttttc tctgaacaag tctagttctt tcaccacgtc
      781 attaaacaaa tcttgcttat cttcttgcgt aagattctgt ttaatatact catctaaagc
      841 ttttctaagc aattcatctc ttgtcatatt agtctcatac ttttctacta aaactctgga
      901 agtcgcattt aacaaagtcg acagttttaa aggatgcttg gtggaataaa ccttatcaaa
      961 ctttctgatt ggtgcgccaa ctttttttgt tcttcctcta ctctgtcttt caacattgga
     1021 ggaagttttt atttcttgaa cttggtgcac ttctaattgc ttattttcag atggtgtaat
     1081 tgcttgctgc tttttctttg cttctgcttc tttttttatt ttggcgagtc ctttgttgtt
     1141 cccaaaaata tcaagtcctt tgatgtcagc caattactcc acctccgcat accaattctc
     1201 gtgttcttcc aattctttca aaatactgat aaataattcg tggcttttgc gatcccattg
     1261 ttttaagaga cctttctttg tcttctccat cgtaatacct gatccgtcgt atcgttttaa
     1321 gcgcgcattt ttgagtacaa catttttaat caaatgttcc ccataaatct cttgggcttg
     1381 tttatacatt tcctgatcta ctgcgtcacc gctttccaac atgaaaggaa taacaccagc
     1441 aacatataaa tttgtatcaa attctttcac aaaaaagtcc atatactcaa gatattgcat
     1501 cgcatttctc atcgatttta cttgggtctg taagacgacg attgcccaat ccgcaatgta
     1561 catcgcggat ttactatata cagaaataga aggtgggaca tctaaataga tgacgtcaaa
     1621 ctcatcaaat aatggttcta gcttttcttt catatatttg aattgggata atgaatcatt
     1681 atattggtct ttgatccaat catcatacat ttcaaaggac atgtctgctg gaagtatata
     1741 gaggttattg attactttat agacagcctc tttaggtgga agattgttta tcaacacgtc
     1801 agtcacagta ttttcgtaaa caatcggttc accttctccg cctccttctt cgttagtgaa
     1861 gttcatatgc gttaagttca tcacatcaga agtatttcct tgcatatcca agtcaattat
     1921 caaggttctt tttccttcat taactgctga ttcaaaccct aacatttgcg cgcacgtact
     1981 tttacctacg ccacctttaa aattaccgat tacatatttc ttcgctacca cgttcctacc
     2041 tcttttcttt tagcaatatt catttgatac tattataaca tatttatttt tagttactac
     2101 caaaaaaaag atatatatgt actaccttat aattaataag taaaaggtag tacataaata
     2161 aggaaaagct gaaatatatt gatttatagc tttcctcaaa gtaatgacgt tatttaattt
     2221 atcgagaagc agagaatact cgcgacttta gtcatgtaga cgaatcagat tttcgataaa
     2281 aaagaagccg tccttcttaa gaacgacaac aaatcactag attaattttt tcaactgttc
     2341 ataaaagttt tcatgcgttc cacataacaa tactggaata accttgtttt ctataatctc
     2401 gtaagctact ctatatgttg tgcccgcata tttgaaccca ctagaccaaa tacctgataa
     2461 atccccagtt ttttgttcac ccttatatgg atcaatcgca atttcatcat aaattaaatt
     2521 caaaaatttt tctttcaatg gcttctcttt tagcttttta aatacttaat gacatgtttt
     2581 gaaggaacga tttcataagc caatttctgt tgccaactcc tctttagtca ttactttaga
     2641 attagtaagt gtatcttcag caatatctct aaaggaagaa tgcattttgt tttttctatt
     2701 cttaaattct acaagaatct catctttatc gtagccttct gcaattatat cagacaaaat
     2761 atcttcgcta aaatcataaa attctttttg tggttcaaca aattcataaa gaataccatt
     2821 ctctaccaac tttgcttcaa cttcgactcc attaggaaca ttaaaatctt taggtactgt
     2881 caacatgatt gaattgcctt gttttcttgt ttttgtaatc atttaaatcc ctcatttcta
     2941 acagtatgta attacttagt aaatacatta taccacgaga taatgtattt acaagtaatt
     3001 actgtgactc gtaatgcgtc cttgctgaat aaatttcaac cacgtgttca tcttcatcta
     3061 ccttataaac aacccggtgt tgtctattca atcttctaga atacctacct tcatgtgtag
     3121 gttttaactt ctcaaatgat tgggtaggga gatagggatc ttcctttaaa gtctgaataa
     3181 ccttctcaaa ttgaggtttc aaattagact gtttgatttt ctttaaatca gctttagccg
     3241 agtttttaat catcacagaa tagttattca ttataagtta tcccaatcaa tttcatcaac
     3301 attagtaaat ccactatcat ctttttctcg cttacgaaca acacccaaag tgcctatttg
     3361 ctcaagtaat agcgtttctt tgattgcttt ccaatcatcc aaaccaataa gcaccgcatt
     3421 attttcactg cgctcactaa tgatttcaat ttccgtatga ttctcattta catctttcaa
     3481 caacttataa aaatttttcc gtgctgagct aggatttaag actgtttttg ccatatctac
     3541 tccccctcta atttatatct ccattctaac gtacttaatt aagtacgtaa attcgattgt
     3601 tttgtttaaa ttggagtacc aaaacagcat tgtaaagtgt tatccgtttc ctttataccc
     3661 gtggtgctag ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa
     3721 aaaacgcata tagtagtctc aaaactccca agaaatgagg actacatatg cgttcatcaa
     3781 aatatactga acattataca gatactttta taacattcaa ggaaattatg agaactgttt
     3841 ctaacatata ccacaattgt gtaccagata agattaaaaa ccgaagaaat actgatcaac
     3901 tgaag
//
LOCUS       DAKCAA010000129         3769 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000129 DAKCAA010000000
VERSION     DAKCAA010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.132"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            24..212
                     /locus_tag="OUE31_002707"
     CDS             24..212
                     /locus_tag="OUE31_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCU0223658.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(270..623)
                     /locus_tag="OUE31_002708"
     CDS             complement(270..623)
                     /locus_tag="OUE31_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223659.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            1154..1576
                     /locus_tag="OUE31_002709"
     CDS             1154..1576
                     /locus_tag="OUE31_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCU0223660.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            1573..1803
                     /locus_tag="OUE31_002710"
     CDS             1573..1803
                     /locus_tag="OUE31_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223661.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            2301..2501
                     /locus_tag="OUE31_002711"
     CDS             2301..2501
                     /locus_tag="OUE31_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCU0223662.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            2528..3721
                     /locus_tag="OUE31_002712"
     CDS             2528..3721
                     /locus_tag="OUE31_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCU0223663.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
BASE COUNT         1315 a          621 c          680 g         1153 t
ORIGIN      
        1 aaagtggaaa ggaggagatt gttattataa actacaagtg gatattgtgt cctatttgtg
       61 gaaataaaac aagactacga atacgagtgg atactatact taaaaatttc cctttatact
      121 gccccaaatg taagaacgaa actttaatta atgttcaaaa aatgaatata ataacaatca
      181 aagagccaga cgccaagacg cagagccgat aatttgagaa atgaaactct catcttatcg
      241 gctctttttg tttatctgaa ttttactgac tagccttcaa tatttcttgc ttcattgata
      301 ccttttgcta gtgcttccat taaggatagt tctttgtctg taaagctatc catgtatttt
      361 tctacctgta accttcgagt gcttttaatc aaattatctg taggtaagaa aaattcatca
      421 atagatacat ggagtaatga tacaagatca tacagcactt gtgtacttgg gtgttgtcct
      481 ttgttttcta tatttgttaa ataacgtggg tcaatttcaa tcattgttcc cacttgttca
      541 cgagtgagac cccgtttcat tcgagcctct ttaatcgcta aaccaacggc tctaaaatcg
      601 tatttatctt cttttttacg catactaaat cacctctata cattttactg ttcctatata
      661 accataaaca ggtatagaaa aacatgttat atagtttatg agttcctata gaacactgtg
      721 gaatttatta atgcgatgaa tccaatttca aatagaaagg tcgctgattt tatttaccta
      781 tacaacttta taaaatttag tcatactcct agaaagtaga taaaattggc gacttaatgg
      841 agggaaaagt cgccatgaga aagataatct gtcatctagt tctcttaatt aagttcttat
      901 caaaaaaact tatccacctg tactggatag atatgaccat caatgtggtt ttgcagatta
      961 catagataga aaaatcaaag catatgaaca gagaaaacaa tctgtttatg tgcttttttg
     1021 gtcacttaat aaatatcttt taggatttct cttcatttat gcaacaaatc ccccgttcgt
     1081 gtcggggttt agtatgaagg gagataaaga agcacatgcc actccctttc acgacagaaa
     1141 gggggtgaaa agcatgaaac catcttcttt tcaagaaacc atagaaaatc agtttgacta
     1201 tatctgcaaa caagttattg aagatgaacg aaaagattac ttcaaacatc tagacagact
     1261 atcagcaaaa gaagtctcgt tttctgatat agataactac cttgtcaact ctttttctac
     1321 tgttgatacg tacgtcactg atttccaact atttaaatta tttggattaa gaatcaatgt
     1381 tgaaagtgat ttattaagtg aagccctgcg tcatctttca gagaaaaaac ggaacattat
     1441 tttacttcat tactttatgg atatgagtga tgtggagatt gcggagttac taaatttgaa
     1501 tcgttcgact gtttatcgtc atcgaataag tggactagcc atgattaaag aattcatgaa
     1561 ggagtgtaaa gaatgaaaac agcttatcca agggttccct tccccctcat tgtaaaggcg
     1621 acagatggcg acgtggaagc aattaatcag attgttaaac attatcgagg gtatacctca
     1681 aaacgttcat tacgtcgcat gacagacgaa tatggaaatt ctcatatggt tattgatgaa
     1741 accctacgtg gcagaatgga aacgaaactc atctctaaga ttttatcgtt cgaaattaaa
     1801 tagtcccatt ttttcgtgga agcgtgtcga atcgtatcca cgcttcccga tttgggaggt
     1861 ttgttattcc atcaaagcat attgtgtgtt cagtaggttt tgataggcta acaagccaaa
     1921 cgttctttga caaccaaata aaggcaatcg aatacgtttc ggtaagaaaa gagctgatga
     1981 actaacacgc catgacctac aaaattagtg agcgattcat gttagtaatt cgaaagtaat
     2041 ctttagcagg attgctgcca tgactttctt atcgtgataa tgatactccc gtatagccat
     2101 agtccgagcg ttagaagcgt cacaggcaat gggtacggct acatgagaac catgcagaag
     2161 tgaaattcct gtgagctttg ctagagctgt tcgattgcta agatattctt ctcttgtcag
     2221 tgtattatta taaaactatt tgatataatt ataggtgaat attggagttt tcctagccta
     2281 taattgggaa aggagtaata atgataacgg tcacaaaaaa ggatttagtt gagctaggat
     2341 atggaacttc tttttcagca gacatcataa aaaaagcaaa agaattgatg attacaaaag
     2401 ggcatatcta ctatcaatct cgaaagctag atagagtccc tcgtgaagct gttgaagaaa
     2461 ttctaggaat tcggttttca aatgaaaaca ggtctgagta gtttttgcac agtaaggagt
     2521 aaaaactatg gttaaagacc caataaaaaa agcaaagaat ggaacctatt attttcgtgc
     2581 aaatctaggt tatgattcta aagggaaaaa aattcaaaaa tatcgtagtg gattcactac
     2641 taaaaaagaa gcaagagaag aatattcgaa actgctattg atgaaaccag aagaattaag
     2701 tgagaataag gataaaatga cgtttaaaca ttatatcttt gaaattttcc ttccatggta
     2761 taagacacag gtaaagctca gaacatatga aaatcgctta ccaactatta agaagcattt
     2821 ctcttatttt gataaaatgg ctgtttccga tattgagcct attgatgtgc aaaattggca
     2881 actaaaatta tcaaagaagt gtaagtcttc ttatgtaaga gctgttcaag gactattttc
     2941 agttgctatg gatcgagcaa ttgtccttgg gataaccacc acaaatccat ctaagattat
     3001 tggcaatgtg aaaaagcaaa agtctaaaat tgaattttgg acaaaagaag aatttgaaaa
     3061 agtaatctct ctaatttaca aagaagatta ctatcaacac tttttattta tctctctgtg
     3121 gtttttattt atgactggaa tgcgaattgg tgaagctact gccattcaat gggaagatat
     3181 tgattttgac tcaggagtac taaccatcaa caaaacactc tattacaaga atcaatcgaa
     3241 ttatagattt gttgaaccaa aaacaaaggc gagcgttcgt catattgtat tagataaatg
     3301 cacattaact tatttatccg aatggaagga agtacaacaa aatctaattc agacagactt
     3361 tgtaatgagc tataacggta ttcctaccca aaaacataca ctatcatatg ctattgaacg
     3421 ctatgctaag ctggctggta tccatcgaat cagaatccat gggttacggc attctcatgc
     3481 ttccttgtta atcagtatgg gagaaaatcc acttatcatt aaagatcgtc taggacacga
     3541 agatattgag acgactttag gaacgtatgg acatctttat cctaacagta atttcgaggt
     3601 agctaacaaa ttaaatggag ccatttcctt taaagaagca aaacaaaatt atgatacttc
     3661 accaaagaat caatttactg tagactactt gcgaaacaaa gaaatgaaaa aagtgcaata
     3721 aaagtgcagt aaaaagataa gaagagccag aaacccttgg tataagagg
//
LOCUS       DAKCAA010000130         3762 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000130 DAKCAA010000000
VERSION     DAKCAA010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.133"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(71..364)
                     /locus_tag="OUE31_002713"
     CDS             complement(71..364)
                     /locus_tag="OUE31_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HCU0223664.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(765..1943)
                     /locus_tag="OUE31_002714"
     CDS             complement(765..1943)
                     /locus_tag="OUE31_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCU0223665.1"
                     /translation="MENMSRFKKHITATGKITWYFQAFRTTRRGFNSKREAQLAYLEM
                     EKQHRNKQKRIASNDKFNVVSQKWFEYYRSLNEQKRATYDKREEQVKILNRWIGDKKL
                     SSLSSEELQKFLFILKEKGIDGIDVGYAKNSLQSLVQVLNMIFKYCKKKNLINENPME
                     FVKMPKYQLTVEDLKESVNSLEDKFLTVDELRTFLNYGIIYEELPMSVLFHVLFYTGC
                     RVSEALALQPQDIDFERNEILFYKQTAVKGKSKDFRIETTKSVSSARRVPVTPLVMEK
                     LHELIDVLNKTKRNSNFVVDETYLFVYLDPGKRGVPYRREYVNDHVKRCVERCGINKN
                     FHTHLARHTMASLVAEYCSWDVLKDRLGHTDSTTSKIYRHLTSNERIKPLLAFDSLEN
                     "
     gene            complement(2046..2357)
                     /locus_tag="OUE31_002715"
     CDS             complement(2046..2357)
                     /locus_tag="OUE31_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCU0223666.1"
                     /translation="MSKNNNKNNSSELENCLFNPKKLEDSINKVKRINDLPLVLTNKD
                     LKEQFQISDSTLNRLIKLDNFPRCWFGIKGHYLRDDILEWIKKGKEEYFCDQFRLLRE
                     L"
     gene            complement(2709..2954)
                     /locus_tag="OUE31_002716"
     CDS             complement(2709..2954)
                     /locus_tag="OUE31_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223667.1"
                     /translation="MVDKPKKWQYPLVPLSIILSALEEDPISIKMILKHYDNYIAKLC
                     LTNGFNEVGQFITYVDEYMLRQLEVKLIEAILKFKVN"
     gene            complement(2948..3349)
                     /locus_tag="OUE31_002717"
     CDS             complement(2948..3349)
                     /locus_tag="OUE31_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCU0223668.1"
                     /translation="MQQNYNEKSIQHQFDAYCKKVLRNEAKSIRKRNTRIKDNEEPLN
                     DVNEGKYPQTNFDEQDVYFLFGMEILISDQKLSAAIDQLSDIRRKIILLYYFADFNDA
                     EIGRILNMSTSGIWYQRTKAVEQLKMGYDLW"
     gene            complement(3586..>3762)
                     /locus_tag="OUE31_002718"
     CDS             complement(3586..>3762)
                     /locus_tag="OUE31_002718"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCU0223669.1"
                     /translation="TTQVGKQAKKAKMLPKTGEEDTNMITIFGGLLLLGSLGLIDYKK
                     RESKKSSSRIERSK"
BASE COUNT         1186 a          691 c          476 g         1409 t
ORIGIN      
        1 agttcaagta tgcggtgtag aaccaatatc gcatacttga acttttttca atgagtataa
       61 attaaaactt ctaattttca attcccatca tctgatatgc ccgaccgtct gaacttcttt
      121 tgaaaaagcc aaatgtgatt agataacgtc tttgttcgac ataatcgcca ctagaaaata
      181 cgttcagcag tatcgaatta acctctgttt ctgtataagt cactccatgg tcaaagcgtt
      241 tcaagacttc tttcaatagg atgtatttct tttttgttga acttggtact tgttttactt
      301 ttccatcatt catgaatgtg tctaaaactt tcatcttttc ttgctccgta taagtataaa
      361 ccatcttctt tctccttttg attctaagaa tactccattt atgttagaat attctggatt
      421 ttttattaaa gcggttactc ttaagaaaga tattatcata gtgctctttt ttttactact
      481 acttataggt agatttattc taatccatta ttctccccta ccaataatta aagaaaaaac
      541 tggatcaggg tgttcaaatt acatgctaag aaaaaagaac ccttgaatac caagggttct
      601 ttctcagtct gataacaatg attaacgacg gatttctttg atacttgtga aaagtcatta
      661 aagtattgat ataaaagttt ttctcttttt ctgactacac tttgactaaa gcatagtcac
      721 aacacctatt ttagattcta aaatacctgc acttctgcca aaatctaatt ttctaatgaa
      781 tcaaaagcaa gcaaaggctt tattctttcg tttgatgtta aatgccgata tatttttgaa
      841 gttgtactat ctgtatgacc taaacgatcc tttaaaacat cccaactgca atactcagct
      901 actaaactag ccatcgtatg acgagccaga tgagtatgga aatttttgtt gattccacat
      961 ctctctacac agcgcttaac gtggtcattt acatattcac gacgataagg aactccacgc
     1021 ttaccaggat caagataaac aaataaataa gtctcgtcta caacaaaatt gctatttctt
     1081 tttgttttat ttaatacatc aattaattcg tgcaatttct ccattactaa cggtgtgaca
     1141 ggtactcttc tagcagaact aacagatttt gtagtttcaa ttcgaaaatc tttgcttttt
     1201 ccttttactg ccgtctgctt ataaaataag atttcatttc gttcaaaatc tatatcttga
     1261 ggttgtaaag caagtgcttc actcacacga cacccagtat aaaacaaaac atgaaaaaga
     1321 acagacatgg gtaattcttc ataaatgatc ccataattta aaaaagttcg caattcatct
     1381 actgttaaaa acttatcttc taaactatta acagactctt ttaaatcttc aactgttaac
     1441 tgatacttag gcatttttac aaactccatt ggattttcat ttatcaaatt ctttttctta
     1501 caatatttaa aaatcatatt tagaacttga acaagagatt gtaaactatt tttagcataa
     1561 ccaacatcaa tgccgtcaat tcctttttct tttaaaataa aaaggaattt ttgtagttct
     1621 tctgaagata aactgcttaa ttttttatca ccaatccatc gattaagtat ttttacctgt
     1681 tcttctcgct tatcatatgt tgccctcttt tgttcgttta gtgatcgata atattcaaac
     1741 cacttttgac taaccacatt gaatttatca ttactagcaa ttcttttttg cttatttctg
     1801 tgttgttttt ccatttcaag ataagctagc tgagcctcac gcttagaatt aaaacctcgt
     1861 ctcgtagttc gaaaagcctg aaagtaccaa gtaatttttc ctgttgcagt aatatgtttt
     1921 ttaaaacgac tcatattttc catttgtttt tacccccaat tatgaaggaa cccaacaatc
     1981 ggaaactctt gaaaatcttt ctatttataa aataattata caatatacag acgaaaaaat
     2041 aaattctaca attctcgtaa taaacgaaac tgatcacaaa agtattcttc ctttcctttt
     2101 tttatccact ccaaaatatc atctctaagg taatgccctt tgatgccaaa ccagcatctt
     2161 ggaaaattat ctagttttat aagacgattt aaagtactat cacttatttg aaattgttct
     2221 tttagatctt tatttgttaa aactaacggt aggtcattta ttctctttac tttattgata
     2281 gaatcctcta gctttttggg attaaataaa caattttcta actctgatga attattttta
     2341 ttgttattct ttgacatgat tatctcttcc cttctattat taaggattaa tctatcagct
     2401 gcctttgtca aaagcacata ggaatttcac ctctccccaa gtttacggcg agccttacgg
     2461 aagtatcatt atcccaacct caaatcatcg ctttttattg actataaaaa ttattttaga
     2521 atatttatcg ctccttcttt ataataagag atcatggcgt aactaaaata tgctccttga
     2581 agtgttaacg tactgataga atatatttat ttttcaatga acaataggtt ttctccctaa
     2641 aagaatccgc taatctaaag tattagaaga ctctttttgg tagaaaaagt agaaagggga
     2701 gtttttagct agttaacttt aaatttcaat atagcttcta ttaatttaac ttctaattgc
     2761 cttagcatat attcatccac ataggtaata aattgcccca cctcattaaa tccatttgtt
     2821 aaacataact tagctatata attatcataa tgtttgagta tcatcttgat cgaaattgga
     2881 tcttcttcta gagcagatag gataatagat agtggaacta atggatactg ccattttttg
     2941 ggtttatcta ccataggtca taccccattt tcaattgttc aactgccttc gttcgttgat
     3001 accagatacc acttgtactc atattgagaa ttctaccgat ttcagcatca ttaaaatcgg
     3061 caaaataata aagtagaata atcttccttc ttatatccga taactgatca attgctgctg
     3121 ataacttctg atctgaaatt aatatctcca ttccaaataa gaaatagaca tcttgttcat
     3181 caaaattagt ttgtggatac ttcccttcat ttacatcatt cagtggttcc tcattatctt
     3241 ttattctagt gtttcgtttt cgaatagact tagcttcgtt tcgtaatact tttttgcagt
     3301 aggcatcaaa ttggtgttgt atagatttct cattatagtt ttgttgcacg atcaatatgc
     3361 tcctttatcc cctttccact aatacaacaa tcagagagtg cctttttttc gaaaaaacta
     3421 aaaaaaaaca aaaaataatc atacttttta ggtggaattt cattctcaaa aaaaaaaaaa
     3481 acgattagta tcactaatcg tttttgagta ttccttgcaa aagccaaatt acttttatag
     3541 ttaaaatttg atattgataa tcatccttct ttcggtagtg ggtaatcatt ttgatctttc
     3601 tattctactt gatgattttt tagactctct ctttttataa tcaattaggc ctaaacttcc
     3661 caacaataga agaccaccaa agatagtaat catatttgta tcctcttcac ctgttttggg
     3721 taacattttc gcttttttag cttgtttccc tacttgtgta gt
//
LOCUS       DAKCAA010000131         3465 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000131 DAKCAA010000000
VERSION     DAKCAA010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.134"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..287)
                     /locus_tag="OUE31_002719"
     CDS             complement(<1..287)
                     /locus_tag="OUE31_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223670.1"
                     /translation="MGKDKRIVWKDQSDLKIILTISQFIETYEIKSSREYQKQLSKNP
                     HSAPSMWFIINKYGSWNNLLNSIGIDNNGSKKWARMETDELIKVAQIFIDS"
     gene            complement(647..994)
                     /gene="rplS"
                     /locus_tag="OUE31_002720"
     CDS             complement(647..994)
                     /gene="rplS"
                     /locus_tag="OUE31_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HCU0223671.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(1130..1891)
                     /gene="trmD"
                     /locus_tag="OUE31_002721"
     CDS             complement(1130..1891)
                     /gene="trmD"
                     /locus_tag="OUE31_002721"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HCU0223672.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            complement(1881..2402)
                     /gene="rimM"
                     /locus_tag="OUE31_002722"
     CDS             complement(1881..2402)
                     /gene="rimM"
                     /locus_tag="OUE31_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HCU0223673.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            complement(2572..3363)
                     /locus_tag="OUE31_002723"
     CDS             complement(2572..3363)
                     /locus_tag="OUE31_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223674.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
BASE COUNT          961 a          695 c          598 g         1211 t
ORIGIN      
        1 tctgaatcaa taaatatttg tgccactttt attaattcat cggtctccat tctagcccat
       61 tttttagatc cgttattatc aattccaatg ctattcagca aattattcca cgagccatat
      121 ttattaataa taaaccacat gctgggagct gaatgtggat ttttcgataa ctgtttctga
      181 tattctcgac tagattttat ttcgtaagtt tcaataaact gactaattgt taatataatt
      241 tttaaatcgc tttgatcctt ccaaacaata cgcttatctt ttcccattac aaaaaactcc
      301 taaaattatt taaatagaaa cctatcacat aaacttttta gcacaatggt atatgttttg
      361 cttttttcga aagcattcaa cctttttagc aactcgggtt caaaaattgc taaattcggt
      421 aagtgtttag gtatttttcg tattaaattt gtcgtcaaaa tgactactaa ttttttcggt
      481 attttgacga taatagtagt caatattggg agattcagga caatttgaga gaacattaga
      541 aaaaaaggcc caaaacatat taaaaatgtg atagagaaaa aagaaaaagt ccttgatata
      601 caaggacttt tcacagattt cagatttcca aggaagtttt ccgtgtttat cttctgattt
      661 ctttgatacg agcagctttt ccgtgtaatg cacgtaggta gtacaatttt gcacgacgta
      721 ctttaccgta gcgaactact tcgatttttg caacacgtgg tgtatgcaat gggaatgtac
      781 gttcaacgcc cactccgtta gaaactttac gtactgtata agtttcgctg attccagcac
      841 cgcggcgttt gataacaaca ccttcaaata actggatacg ttcacgagta ccttcaacaa
      901 cttttgcgtg aacacgcaca gtgtcaccag ggcggaacgc tgggatgtca gaacgtaatt
      961 gttcttttgt taattcttcg attaatggat tcatggtttt cttctcctta ttccaaatat
     1021 tcttatgagc ttttctcaca gcggaatatc gtaatagtta agtgcttttg cactcaccat
     1081 aaaatactaa catattatca acctactgta aagaagattt tagaaaaagt cacttggctt
     1141 catctgctgt tttttcttgt tcttctttct tgatttcttc taaaaatttc gtcatttgag
     1201 gtgtccattc aagtgtttcc aaaagatcag gccgacgttg ataggtcctt cttagtgatt
     1261 cttttaattg ccattcttca atcaatttat gatttccatt tgtcaatact tctggtactt
     1321 tcatcccttt atattctgcc gggcgagtat attggggatg ttccaataaa ccggttgaat
     1381 aagaatccgt ttgagctgaa gtctgattcc ctaacacatc tggcaaaagc cgaactgttg
     1441 catcgatcat gaccatcgca cctaattctc ccccagtaag gacataatct cctaaggaaa
     1501 cttcatctgt cactaatgtg cggatacgtt catcatatcc ctcataatga ccacaaatga
     1561 atactaagtg ttcttcttgt gaaaattctt ctgccatttt ctgatcgaat cgtttaccag
     1621 ctgggtcaag aagaattact ctttttttga catccggtgc agctttttca atggcttgga
     1681 tgttatcata gatgggctgg actttgagca gcatacctgc tccaccgccg tatggataat
     1741 catctactgt ctgatgtttg ttatctgaat aatcgcggaa gttagagata ttgatatcta
     1801 ataatccttt atctacagcc ttaccgatga tggattcccc cataggacct tcaaacattc
     1861 ttggaaataa agtcaataca tcaatcttca tcgtcaatca gtccttctgg aatttctaca
     1921 cggaccactc cagcttctaa atcgacttct ttgacgacag aagcgatata tggaagcaat
     1981 atatcagctt ttttcggacg ttgaacgacc caaacatcat tggcacctgg tgacaagatt
     2041 tcttttactt tacctaactc agttccatct tctaatacat gcagaccgat gatctcatgg
     2101 taatagaatt cattttcagc tagatctaca gagttgtctt ttgacacttt taatatgcca
     2161 tcccgatatt tttccacatc attgatagaa ggatgtcctt caaaactcaa taagtcaaaa
     2221 tttttatgtt tgcgatgact tttgactgtt aattccacag gtgcttttcc gtcttggaat
     2281 agtgttagca ccgttccttt tttgtaacgt tcttctggga aatccgttgt tgagataaca
     2341 cggacttcgc ctttgatacc ttgtgtgttt acgatttttc ctacattcaa gtattcagtc
     2401 aacttatatc cccatttctt ttttgtctgt tttattttag catgtgtgaa gaggcaattc
     2461 tagttttctt ttaaggtatt aagccaaaat tatgcaaaaa tgcggcgtgc tatttttgat
     2521 tacttcctgt gacttggagt taaatgatgg gctcagatca gcgcgctgat ttcacaacct
     2581 cttcatagaa actgccatct tcaacgcaga cataggatct tgatgagtga tcgtataggc
     2641 atttttcggt tcttgccagc ttacttctac ggctcgattc gtcgtatcac ccatatcaac
     2701 agtaatttta ccaaattgtt caggtgctgg tagactgttt tcttccaaat aagctacgat
     2761 ttctttagct aatagtaagg gatcttggcc ttctatatta ttcccacgga ttcgaatacg
     2821 ccagtttcct tcttgccatt caagaaaact tgaacctgct gcaccttgct gataccctgt
     2881 gattcgagaa cctaagtcca cttgctgacc atttgtgtcg atctcaaatg gctgcaaaac
     2941 ttggattgtt tcttgactag aagcaaaccc atattgatat agataggttg caataggcgt
     3001 ttcttgattc aattcgtcag cattcaaccc gaggggacga tctgttctgt aatataaaat
     3061 agaataacct tgctttgtat gtgtcgctgc gatattgaga tagcctgaag agactggtac
     3121 atctagaggc atgggaacat ttggctgttg ttctttcaac tggtctaaag cagtcttttt
     3181 ctcattattt gaggtagcca ttgtttgttc agtggtggaa gccgttttgg tactactttt
     3241 ttctggactg gtaacagttt cagatatact gcttgataga tgtgtattgt ctgattcttg
     3301 agtaaccgaa ctacaagcgc ttaacaatag agcaaatgga ataaataaca ttttctttct
     3361 cattggctgt tcactccctc ctcctataag gatacgcttt cttgcttgtt ttgccaaata
     3421 atcatttctt caattaataa aaaaaacaaa aaagctgcac tcgaa
//
LOCUS       DAKCAA010000132         3403 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000132 DAKCAA010000000
VERSION     DAKCAA010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.135"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(75..1073)
                     /locus_tag="OUE31_002724"
     CDS             complement(75..1073)
                     /locus_tag="OUE31_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HCU0223675.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1148..1444)
                     /locus_tag="OUE31_002725"
     CDS             complement(1148..1444)
                     /locus_tag="OUE31_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCU0223676.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1437..1730)
                     /locus_tag="OUE31_002726"
     CDS             complement(1437..1730)
                     /locus_tag="OUE31_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223677.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1876..2427)
                     /locus_tag="OUE31_002727"
     CDS             complement(1876..2427)
                     /locus_tag="OUE31_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HCU0223678.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2601..2900)
                     /locus_tag="OUE31_002728"
     CDS             complement(2601..2900)
                     /locus_tag="OUE31_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HCU0223679.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2927..3193)
                     /locus_tag="OUE31_002729"
     CDS             complement(2927..3193)
                     /locus_tag="OUE31_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HCU0223680.1"
                     /translation="MDSLPVELQALCWNLIDQNVQKQFPLDYLQIFEFSTEKGNQKLV
                     HRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY"
BASE COUNT          993 a          669 c          461 g         1280 t
ORIGIN      
        1 taaaaaaact gattctaaga aaattaaata atttttctca aaatcagttt ttctttgata
       61 aataatattt tcaattattt aatcatttga aaattgttag tcattccaat acgttgagaa
      121 attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt gtttccatca
      181 tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat tagatctttc
      241 atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg agaatcatac
      301 aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact tgaaattcct
      361 gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc ttctactact
      421 ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa ctgttgattt
      481 tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg cgttaaataa
      541 actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa atattctcca
      601 gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt tccatcttct
      661 gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc attaatcacg
      721 gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta gcttttatat
      781 tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga agctttattc
      841 gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga acttgcactt
      901 gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt tttacttttt
      961 ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt ctcagatgta
     1021 caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt cattatattt
     1081 ccccctttca atttctccct cacgtactta ttctatcaga caattaattg atctaaatgg
     1141 taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag cggtctcttc
     1201 cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat cctctacagc
     1261 gataagttct cattattttt gggctattag tattattttt cttagttaga gctatgagtc
     1321 caactatgat taccccaact gtcttaatta cttttccttt atctatattc ggatgcgcaa
     1381 gcatatattt atataaccaa tatccaccgt aaattaaacc acctaataca atcagcttag
     1441 ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct tgcagagaaa
     1501 ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat catgttttcg
     1561 attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat ctgttgccct
     1621 cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc ctcaaaaaag
     1681 tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat ctacacaccc
     1741 cctgttattt tttacataat gaaaatagca tattactggg tacattgata attcatataa
     1801 catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt ataagtaaca
     1861 tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca attgccattc
     1921 attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta tcaatacttt
     1981 ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt gttcataagc
     2041 cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga ttttcttttc
     2101 tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa gaaatacccg
     2161 aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag taaatcctaa
     2221 ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg gttctgtatc
     2281 tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc ctttgatcgc
     2341 ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa cttctgtttg
     2401 tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt ttgttcaagc
     2461 acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt catattcttt
     2521 ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa catttcgcaa
     2581 tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca aaccaatcgt
     2641 ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt aatgaaataa
     2701 actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt catcactaaa
     2761 cgtggtagat gaacatcttc aggaagcata cccatttcaa tttcctcttt ttccatcgta
     2821 acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt ttccagtact
     2881 tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag tattcttctg
     2941 gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga gacactgatt
     3001 tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct tcttgacgat
     3061 gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga tagtctaaag
     3121 gaaattgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt aattccaccg
     3181 gcaaactgtc cattactccc tttgtgacat aacgttatcc tttattttga aacatttctt
     3241 ttccctcctt tgccataaaa atagcccaat cttctattaa agaagattgg gcttcatgga
     3301 tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact acacaattat
     3361 taaagttttt catatctctt tgtttagtaa gtttttctaa atc
//
LOCUS       DAKCAA010000133         3390 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000133 DAKCAA010000000
VERSION     DAKCAA010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.136"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            647..964
                     /locus_tag="OUE31_002730"
     CDS             647..964
                     /locus_tag="OUE31_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCU0223681.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="OUE31_002731"
     CDS             complement(1055..1420)
                     /locus_tag="OUE31_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223682.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="OUE31_002732"
     CDS             1628..2110
                     /locus_tag="OUE31_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223683.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="OUE31_002733"
     CDS             2307..3197
                     /locus_tag="OUE31_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HCU0223684.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1172 a          519 c          619 g         1080 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac
//
LOCUS       DAKCAA010000134         3332 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000134 DAKCAA010000000
VERSION     DAKCAA010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.137"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..411
                     /locus_tag="OUE31_002734"
     CDS             <1..411
                     /locus_tag="OUE31_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223685.1"
                     /translation="GLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAP
                     QEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLT
                     ELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            521..571
                     /locus_tag="OUE31_002735"
                     /pseudo
     CDS             521..571
                     /locus_tag="OUE31_002735"
                     /inference="COORDINATES: protein motif:HMM:NF019662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            605..1981
                     /gene="tet(L)"
                     /locus_tag="OUE31_002736"
     CDS             605..1981
                     /gene="tet(L)"
                     /locus_tag="OUE31_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCU0223686.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            2545..>3332
                     /locus_tag="OUE31_002737"
     CDS             2545..>3332
                     /locus_tag="OUE31_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCU0223687.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKGFCCKVLNLLSN"
BASE COUNT         1065 a          503 c          678 g         1086 t
ORIGIN      
        1 ggcttatact atagccctgt tagtacccca gcagattttc ggatgcttgc tcctattgta
       61 ttggaacaag tcttaaaaaa agctggaaca gaattgttag agccatatct tagttttaaa
      121 atttatgcgc cacaggaata tctttcacga gcatacaacg atgctcctaa atattgtgcg
      181 aacatcgtag acactcaatt gaaaaataat gaggtcattc ttagtggaga aatccctgct
      241 cggtgtattc aagaatatcg tagtgattta actttcttta caaatggacg tagtgtttgt
      301 ttaacagagt taaaagggta ccatgttact accggtgaac ctgtttgcca gccccgtcgt
      361 ccaaatagtc ggatagataa agtacgatat atgttcaata aaataactta gtgtatttta
      421 tgttgttata taaatatggt ttcttgttaa ataagatgaa atatttttta ataaagattt
      481 gaattaaagt gtaaaggagg aattaattat gaagtgaaat gaatgtaaca gggttcaatt
      541 aaaagaggga agcgtatcat taaccctata aactacgtct gccctcatta ttggagggtg
      601 aaatgtgaat acatcctatt cacaatcgaa tttacgacac aaccaaattt taatttggct
      661 ttgcatttta tcttttttta gcgtattaaa tgaaatggtt ttgaacgtct cattacctga
      721 tattgcaaat gattttaata aaccacctgc gagtacaaac tgggtgaaca cagcctttat
      781 gttaaccttt tccattggaa cagctgtata tggaaagcta tctgatcaat taggcatcaa
      841 aaggttactc ctatttggaa ttataataaa ttgtttcggg tcggtaattg ggtttgttgg
      901 ccattctttc ttttccttac ttattatggc tcgttttatt caaggggctg gtgcagctgc
      961 atttccagca ctcgtaatgg ttgtagttgc gcgctatatt ccaaaggaaa ataggggtaa
     1021 agcatttggt cttattggat cgatagtagc catgggagaa ggagtcggtc cagcgattgg
     1081 tggaatgata gcccattata ttcattggtc ctatcttcta ctcattccta tgataacaat
     1141 tatcactgtt ccgtttctta tgaaattatt aaagaaagaa gtaaggataa aaggtcattt
     1201 tgatatcaaa ggaattatac taatgtctgt aggcattgta ttttttatgt tgtttacaac
     1261 atcatatagc atttcttttc ttatcgttag cgtgctgtca ttcctgatat ttgtaaaaca
     1321 tatcaggaaa gtaacagatc cttttgttga tcccggatta gggaaaaata taccttttat
     1381 gattggagtt ctttgtgggg gaattatatt tggaacagta gcagggtttg tctctatggt
     1441 tccttatatg atgaaagatg ttcaccagct aagtactgcc gaaatcggaa gtgtaattat
     1501 tttccctgga acaatgagtg tcattatttt cggctacatt ggtgggatac ttgttgatag
     1561 aagaggtcct ttatacgtgt taaacatcgg agttacattt ctttctgtta gctttttaac
     1621 tgcttccttt cttttagaaa caacatcatg gttcatgaca attataatcg tatttgtttt
     1681 aggtgggctt tcgttcacca aaacagttat atcaacaatt gtttcaagta gcttgaaaca
     1741 gcaggaagct ggtgctggaa tgagtttgct taactttacc agctttttat cagagggaac
     1801 aggtattgca attgtaggtg gtttattatc cataccctta cttgatcaaa ggttgttacc
     1861 tatggaagtt gatcagtcaa cttatctgta tagtaatttg ttattacttt tttcaggaat
     1921 cattgtcatt agttggctgg ttaccttgaa tgtatataaa cattctcaaa gggatttcta
     1981 aatcgttaag ggatcaactt tgggagagag ttcaaaattg atcctttttt tataacagga
     2041 attcaaatct ttttgttcca ttaaagggcg cgattgctga ataaaagata cgagagacct
     2101 ctcttgtatc ttttttattt tgagtggttt tgtccgttac actagaaaac cgaaagacaa
     2161 taaaaatttt attcttgctg agtctggctt tcggtaagct agacaaaacg gacaaaataa
     2221 aaattggcaa gggtttaaag gtggagattt tttgagtgat cttctcaaaa aatactacct
     2281 gtcccttgct gatttttaaa cgagcacgag agcaaaaccc ccctttgctg aggtggcaga
     2341 gggcaggttt ttttgtttct tttttctcgt aaaaaaaaga aaggtcttaa aggttttatg
     2401 gttttggtcg gcactgccga cagcctcgca gagcacacac tttatgaata taaagtatag
     2461 tgtgttatac tttacttgga agtggttgcc ggaaagagcg aaaatgcctc acatttgtgc
     2521 cacctaaaaa ggagcgattt acatatgagt tatgcagttt gtagaatgca aaaagtgaaa
     2581 tcagctggac taaaaggcat gcaatttcat aatcaaagag agcgaaaaag tagaacgaat
     2641 gatgatattg accatgagcg aacacgtgaa aattatgatt tgaaaaatga taaaaatatt
     2701 gattacaacg aacgtgtcaa agaaattatt gaatcacaaa aaacaggtac aagaaaaacg
     2761 aggaaagatg ctgttcttgt aaatgagttg ctagtaacat ctgaccgaga tttttttgag
     2821 caactggatc caggagaaca aaaacgattt tttgaggaaa gttataaatt attttccgaa
     2881 cgatatggca agcaaaatat tgcttatgca acagttcata atgatgagca aacccctcac
     2941 atgcatttag gtgttgtgcc tatgcgtgat ggaaaactgc aaggaaaaaa tgtgtttaat
     3001 cgtcaagaac tgttatggct acaagataaa ttccccgagc atatgaaaaa acagggtttt
     3061 gagttgaagc gtggtgaacg tggctctgac cgtaaacata ttgagacagc taaatttaaa
     3121 aaacaaactt tggaaaaaga gattgatttt ctagaaaaaa atttagcagt taaaaaagat
     3181 gaatggactg cttatagcga taaagttaaa tcagatttag aagtaccagc gaaacgacac
     3241 atgaaaagtg ttgaagtgcc aacgggtgaa aagtccatgt ttggtttggg aaaagggttc
     3301 tgttgcaaag ttttaaatct actatcaaat aa
//
LOCUS       DAKCAA010000135         3009 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000135 DAKCAA010000000
VERSION     DAKCAA010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.139"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(332..676)
                     /locus_tag="OUE31_002738"
     CDS             complement(332..676)
                     /locus_tag="OUE31_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223688.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(752..1999)
                     /locus_tag="OUE31_002739"
     CDS             complement(752..1999)
                     /locus_tag="OUE31_002739"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HCU0223689.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            complement(1996..2802)
                     /gene="proB"
                     /locus_tag="OUE31_002740"
     CDS             complement(1996..2802)
                     /gene="proB"
                     /locus_tag="OUE31_002740"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HCU0223690.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
BASE COUNT          842 a          626 c          577 g          964 t
ORIGIN      
        1 agttgcttgt atgaacaagc ttctgaaatg tatgcacgct atggttaggg cacatacaga
       61 gtacgactat gcgtacgcgg tctcagtgga ccattaacta aaccacttac agtataccac
      121 ttctttgccc agatcgaaaa ttttttatga acggggcttt atttggtgtg ccttgatttt
      181 gtcgctttcg tttacgagct atttttcttg caccttttac ttgactaatc gtaggaaaag
      241 aggctgtgac aaaatctttg tcacagcctc taaaaagtcc ggcagttttt tgccgatctt
      301 caaggcactc tacttatcgt acggatattt tttagcggaa agtccgattc aagtggtttt
      361 tattcagctg atatttataa gataagtgaa aaatcccagc aatcagtagc gtaatcgtat
      421 aagcgattga atgatcgaaa aaagaatagt aattgattgt cgctaataag cataatgcaa
      481 ccatgtaact aatgtgcaag cgtgtaacca gccctttttg cccgattttg tcaaaatact
      541 gcgaccattt ttcccgttga ctccctatgc ttcgtttttt gaattgaaag aaaagggata
      601 aaataccgac tcccagaaaa gcagcgatat tcagagaaat aaggtaaata aaaaaaatca
      661 ttaaaatttc aaacatattg acacctttct agttggatag aacctttaca gaaaaaaggc
      721 aaaaggcggg aataatgttt cacacgaaac attattcgcg gatttgtcca tcgccataaa
      781 tgatatattt tgtggaagtt aattcattta accccattgg accacgggca tgcaactttt
      841 gagtagagat accaatctct gcaccaaaac caaataccga tccgtctgta aaacgagtgg
      901 aggcattgac atagacagcc gccgcgtcca cttcatttaa gaaacgttga ctagccgcat
      961 aactatctgt cacgatcgtt tctgaatgtt tagtattatg ccgattgata tgtgcaattg
     1021 cttcatccaa agaatcgacc actttgacag caaggatata atctagatat tcagtatccc
     1081 aatctgtgtc ttctgctaaa gcagccgtct ctagatattc taacgcacga gcatccgcac
     1141 gtaaagagac cccgtgttct accagttctt tttcaatagc tggcaagaaa aaaggtgcga
     1201 tctcagaatg gatcagcaat gtttctgccg cgttacagac agatggacgg gaagcttttg
     1261 cattgacgat gatgttcact gccatagata actgtgcttc tttatcgata tatacgtgat
     1321 tatttcctgt acctgtttca atgataggta ccgttgcctg ttctttgact cgttggatta
     1381 attttgctcc gcctcgagga atcagcacat ctaagtattc tgtcaatcgc atcaactgtc
     1441 ctgcagtttc atgagaagta tcatcgacaa actggatggc ataaggagat tcgccagcac
     1501 tgaccagtac ttgctgcaat aattggacta ataattgatt cgagaagaat gcttctttgc
     1561 caccgcgaag gataacggca ttccctgatt tgaatgctag actagctgca tctgtcgtga
     1621 catttggacg agattcgtaa atgatgccgg tcacgcctag tggcacgcgc tttttgccga
     1681 ttctcaatcc gtcggtgttc gtccacatct catctacttt tccaatagga tcgtctaacg
     1741 aagcaatttt ttcgatctct gtagccatgg cattgattcg ctcaggtgtc agctgcaagc
     1801 ggtcttgcat cgtttcactg atattgtttt cgactgcttt ttctaagtct ttatgatttg
     1861 cttcaatgat cgcttgttga ttctttttga tggtttgtgc catttgaaca agtagctcat
     1921 ttttgcggtt tgtaggcata agtgctagtt gttgcgcgct atcttttgcc tgttgtccta
     1981 attgcatcaa gtcagtcatt tcaagtcctc cttaaataaa gtacctactt cttttcctgc
     2041 aagaatatca aaaataattg ccggattttt tccatttgct aaaatcattg cgctgtttgc
     2101 ttcaaatatc ctagaagcgg cttttaattt actctgcata ccgcctgttc caaatgtgct
     2161 accagcacca cctgcttgtg ccagaatctt ttcatcgatt ttatcgatat agcgatacat
     2221 ctgagcctcg ggatttgtag tcggattatc tgaataaaac ccgtcgatat cagaaaggac
     2281 gatcaaaagg tctgccgcga caagttttgc catgatggct gacagctgat cattatcgcc
     2341 aaattttgtc agatgatcta attcatccac tgctacagta tcgttttcgt tcacgatagg
     2401 gatcgtgtcc ataatcaaaa gctgttccaa tgtattcctc acatttttac gactttcagg
     2461 ataatctacc acgtctcttg tcacgaggat ctgtgccgtc tgttgattat atacactgaa
     2521 tctttgatta tagatattca tcagttcggc ttgaccaaca gccgccgcag cttgctgttc
     2581 aggaatcaaa gtcggacgtt ctgacaaatg taatttatgc ataccaacgc ctacagctcc
     2641 tgatgagact aagatcactt cctttccccg atttctaaga tcagaaagga caaaagctaa
     2701 ctgatcgatt gccgcaagat tgatatttcc attgggataa atcaatgtac ttgttcctac
     2761 tttgacaata attcgttttg catttttaat ttctttacgc atgtgacacc tcaatcaaat
     2821 atccactcat taatttcgtt ctattctact tgttttgacg agtaaagtca tgtaaaaaat
     2881 agtttttttg tacaacttgc agtcgtttgg aaaaagaacg aattaatggt ttactttaag
     2941 atagcagaat ttcttgaaga atttgtaaag aaagtctttt acagcctcgg atatgttaga
     3001 ataggagta
//
LOCUS       DAKCAA010000136         3009 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000136 DAKCAA010000000
VERSION     DAKCAA010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.140"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            373..789
                     /locus_tag="OUE31_002741"
     CDS             373..789
                     /locus_tag="OUE31_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCU0223691.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            803..1369
                     /locus_tag="OUE31_002742"
     CDS             803..1369
                     /locus_tag="OUE31_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HCU0223692.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            1392..2378
                     /locus_tag="OUE31_002743"
     CDS             1392..2378
                     /locus_tag="OUE31_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCU0223693.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(2533..>3009)
                     /gene="scm"
                     /locus_tag="OUE31_002744"
     CDS             complement(2533..>3009)
                     /gene="scm"
                     /locus_tag="OUE31_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HCU0223694.1"
                     /translation="STDTSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSST
                     TTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNR
                     TNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT          905 a          567 c          631 g          906 t
ORIGIN      
        1 taaaggaata agatgcccga gataagcctc catgagcaag acacaggtgt cacaacctct
       61 gttacaacct cttgttataa acggtgttcc agaagtagct tcttcgaaaa ataagccgaa
      121 atttcacaaa aacttgaaaa gtaattttcg taaattcctt cttatttctt gaagttgccc
      181 acttctgtca caacctcttg ttataaacgg tgttccacct gctgcttctc ggtaataagc
      241 ccaaagaatt agaaaacatg gaaagctgtt ttctattctt cgttcttatt actcaaagca
      301 agacacaggt gtcacaacct cttgttttta tgctaaaatt gggtgagtta atctggaaaa
      361 aggagaacaa aaatgagcct taaagaattt gctgaaaaaa gtctgctcaa accttgggat
      421 gtttttatta ttttgctttt gactgttctt tcttttttac cagtcatgat ttttggtctt
      481 cagcaaaaca ccgcaacagc agaaaaagaa gcggtactgc gtgtggatgg cacagaaatc
      541 aaaacattcc ctttgatggc tggagaagag agcaacacat atacttacaa agatgaacac
      601 ggagattata acttgatcga gatagatggc gatcgagtac ggataaaaga agcagattgc
      661 gatgaccaga tctgcgtacg tcgaggctgg gcaacgaaaa atggcgaaac catcgtctgt
      721 ttgccacata aattagtgat cgaagtccgt tcaacagatg gaggtgacga agacagtctg
      781 atttattaga ccttcacaca ccatgagtaa attacaaaaa atgatttata tttcgctact
      841 tgttgcacaa ggagtgatca ttggtttatt ggaaaatatg atcccttatc ctttttcttt
      901 tgcgcctggt gcaaaactag gcttagccaa tctaatcacg atcgttgcca tttttaccat
      961 gaaaaaacaa gacagcttct tactactttg gctacgacta ttcctgacta ctttgctagg
     1021 cggaacgatt tccacattcc tttatagtat gagtggtgct ttgcttagtt attttggaat
     1081 gttattggtc aagcaattag gaccaaaacg tgtcagtatc atcggaatta gtgcggccgg
     1141 cggtttcatg cataatgtcg gacagctttt gatggcttct ttcattgcac aatcatggac
     1201 agtcatgttg tacttgccag tcctttcagt tttagggatt ttatcaggga ttgcaatcgg
     1261 gatcgcagcg aattatcttt tacgacatgt gcagacactt caacgattcc aaaaagatta
     1321 tgagcaggga accaaacaaa aatggagccc aatgtttacc aaaaaataat cgtcacacaa
     1381 ggagtttttt tatgaagcta catccaatgt gggaaaacta tcctgcttta agtaaagaat
     1441 tgacagaaac actaaaacgg atggaagaaa ctgtccgcct gaaaaacaaa cctgtcgaac
     1501 aagccatcaa agaaacgatc catgccggcg gaaagctgtt gcgtcctgcc tatcagctat
     1561 tgttctcaca atttggacca gagcaagatc gagacaaagc catcgctttg gcagcttcta
     1621 tcgaaatgct ccatacggcc acactgatcc atgatgatat cgttgatgaa gcggatctgc
     1681 gacgtggtca gcctaatatc cgtagtcagt ttggtaatgt cgtttctgtc tatgcaggag
     1741 actatttatt tgtctgctgt tttaaactat tgtctgatta ctccacttcc ttgaaaagtc
     1801 tccaattgaa ttctcgcagt atggaaaaag tattgaatgg cgaattaggg cagatggatg
     1861 atcgctataa ttatgaactt tctgtaaaag aatatttgga aaatatttca ggtaagacag
     1921 ctgaactgtt ccaattaagt tgttctgttg gcgcttttga aagtggaaca agcgagcgct
     1981 tcgcaaaaaa agcaggagat atcggacttt ctatcgggat ggcctttcag attatcgatg
     2041 atattttaga ttatacaaaa gagagccagg aaatcggcaa acctgtacta gaagacatgc
     2101 gtcaaggggt ctattcttta ccgttgatct actctttgca aaaaaacaaa ccaaagctac
     2161 taccttattt agagaagaaa gcggcaatga cagaagaaga tgtcgacgcc gtacgcaaaa
     2221 tcgttgaaca tacaggaggc gtggaagaag ctaggaagtt agcggcctct tacacagaaa
     2281 aggctttgaa ggaaataaag aaattacctg ccacctctct tcgaacaaaa gagaatctct
     2341 tttcccttac ccaactgatt ttggatcgca aagactgaat agggaaaggt tcgatacgta
     2401 aataaatttc tcagaaggaa atctacgtgt tttttgacaa attgaattgt agttcttgta
     2461 tttatgataa aaagcaaaaa taaagagcaa cgtccgttag cgacgttgct cttttttatc
     2521 ttgaatattt ttttaccttt tcgatttctt ataactcata aaagtgattc ttaaaccgat
     2581 tacaagtaat ataacgcctg cgagtgttat ccaattattc gattgacttc cagttttagg
     2641 aagtgctctt tttgatttgt ttccattgtc attgcttgtt ttattagtta agttaaagtt
     2701 cgtcctgtta tccgaacttg tttttgagaa ggagacactt gcatgacgtg tatcgcttgt
     2761 ggtagacgac gtgtctgtac tatcgcttga agttgatgaa tctgagctat cacttgtggt
     2821 agaggatgta tctgtactgt cacttgaagc tgacgtgtcc gtgctatcac ttgtagtggt
     2881 agatgaatct gagctatcac ttgtggtaga ggtagtatct gtactgtcac ttgaagctga
     2941 cgtgtccgtg ctatcacttg ttgtggtaga tgtatccgta ctgtcgcttg aagctgacgt
     3001 gtccgtgct
//
LOCUS       DAKCAA010000137         2830 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000137 DAKCAA010000000
VERSION     DAKCAA010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.141"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            53..664
                     /locus_tag="OUE31_002745"
     CDS             53..664
                     /locus_tag="OUE31_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCU0223695.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            737..1666
                     /locus_tag="OUE31_002746"
     CDS             737..1666
                     /locus_tag="OUE31_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCU0223696.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1735..2561
                     /locus_tag="OUE31_002747"
                     /pseudo
     CDS             1735..2561
                     /locus_tag="OUE31_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            complement(2609..>2830)
                     /locus_tag="OUE31_002748"
     CDS             complement(2609..>2830)
                     /locus_tag="OUE31_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223697.1"
                     /translation="PLAIRKTIYSTNLIESFNKQIKKYSHRKEQFQNEESLERFLVSI
                     FDTYNQKFLNRSHKGFQQVTDTLASMFTE"
BASE COUNT          967 a          396 c          531 g          936 t
ORIGIN      
        1 gaagtttata tgaagttata aaatttaatt tatattggaa ggaggaaaat aaatgtattt
       61 tatactacct acactttata gccttttatg tgtaatggca ccatgtatta tttatatggt
      121 atttttttgc aaaaaaaata ccctgaaaca caatatcctg attttgattt ttatgctgta
      181 ctgttggaaa gtttttgaat tgactggtac aggtggacta acagatattt tttatagacc
      241 tgatacaggt aggaaatttt ctctagtaca gggcagtgtt aatcttgtac cattcagtgg
      301 actaaacatt agctttatat taaatatagt aatgtgtgtg cccttaggat tcttactacc
      361 aatcatatgg aaaagttata ggaaaatagt tcctgttttc ttggctgggg ctctattttc
      421 actaattatt gaagtctcac aaattataac tacaagagca acagatattg atgatttaat
      481 agcaaatacc tttggtgcgg ttataggctt tatactgtgg gctgttttaa gtagagtggt
      541 gtccttgaag gacaagtcat ctacagtaga ttatttagaa ccttatattt atatattgat
      601 tggttttacc ggaaaattct tactgtattt tcctttctgg tttgcttttg aagtattatc
      661 ctgataattc catagaaaat aatgagtttg agttgagaaa gaatattctt gtacacaact
      721 ctggaaagga ggaagtatga aaagattctt aaaatggggg cttgttcttt tagcgtcttt
      781 gattgtgatt ctaatgtgta cagcggttgt tatttcttat gtgaatcggc cgtatgcaag
      841 agctgtttat gataggatta aacgcattct tgacaaagat ttttatgacc atctatatct
      901 aggttcttca tttgaaataa taaaccttga tacaatggat attcatagct atatgaaaaa
      961 agaccaagaa gaattacccg cctcattgag caaattattt acgattgatt atgcgcttag
     1021 tgtcctaagt ttagatgaac agattacaat tagtcctact gcacttgaca tgcagaaagc
     1081 tgactcatct actgcacatc ttcaagaagg agatatttta tctgtttatg acattatctg
     1141 tgctatggtc ttaccctcag gaaatgatgc agcttatagt ttggcaattt atacaggtgg
     1201 aaaacttgat cctgatgcaa agaatgatga agaacgctat caaagcttca tgaaaaactt
     1261 agatcgttat ctaagtgagc aaggctataa acatactcat tttactgacg ctgctggcta
     1321 tgactccaat gctacaacat cagcggaaga tttgacaaaa gtagctgcaa agctactaaa
     1381 gaatgataaa tttgcagaaa tagttgccaa ggaaacttat agagcaaaat caattaaggg
     1441 aaatgtttat aactggaata ctacgaatca atttatgcaa caagataata gatactttac
     1501 tgaaggtgta aaaggtgtaa aaactggatc gtttgatggg agatacaatc tatgtgtgta
     1561 ttatacatct agttctgata accactattt acttgtaagt tttggttcag agagtgatag
     1621 taggcgttat gtagatgttc aaaatctatt gcataatctg ccttgaaatt tcgtgccttt
     1681 aagcgcgtat ctaaagtttc tttgaaaagt ttgagaatga agaaagtgag cagtcgaaaa
     1741 acggttgctc acttttttgc cctaaaatcg aaaaaatata aaaaagtcct ttacaacacg
     1801 tctcaggaaa aactgctaag tcaattctaa tatcttgtgg agcaagactt gcaccttttg
     1861 atataagaga gcttagagaa ctaatgagcg aagatgaact agaactcgat aaaattggag
     1921 atagaaaaac tgccttgttt gtaataatat cagatacaga tgatacattt aattttgtag
     1981 tttcaataat gtattctcaa ttatttaatc tactatgtga taaggcagat gatgtgtatg
     2041 gtggaagact tccagttcat gttaggtgtc tacttgatga gtttgcaaat atcggtttga
     2101 ttcctaaatt tgaaaaacta atagcgacaa ttcgttcaag agaaatatcg gcaagtataa
     2161 tactgcaagc acaatctcaa ttaaaagcaa tttataaaga ccatgcagat acaatagttg
     2221 gtaactgtga ctctacactt tttctaggag gaaaagaaaa aacaacagta aaagaattat
     2281 cagaaacctt aggaaaagaa accatagacc tatataacac atcagaaaca agatcaaatc
     2341 aaaaatcttt tggtctaaat tatcaaaaga ctggcaagga acttatgagt caagatgaaa
     2401 taactgtaat ggatggtggt aagtgtattt accagctaag aggagcaaga ccttttctat
     2461 ctgataaatt tgatattaca aagcataaga attacaaatt gttggaagat tatgataaga
     2521 aaaacttgtt tgatgtagaa gagtatttaa aacaaagata gcgtaaaata ttttgtgtaa
     2581 ataactcgtc cttctgcaaa ataatgggtt actcagtaaa cattgaagct aatgtatccg
     2641 tcacttgttg gaagccttta tggcttctat ttaagaattt ttgattgtat gtatcaaaga
     2701 tggatactag gaaacgctct agtgattctt cattttgaaa ctgctctttt ctgtggctgt
     2761 atttcttgat ttgcttatta aaggattcaa tcaagttcgt agagtaaata gtcttgcgta
     2821 tggctaatgg
//
LOCUS       DAKCAA010000138         2776 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000138 DAKCAA010000000
VERSION     DAKCAA010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2776
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.142"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(44..1657)
                     /locus_tag="OUE31_002749"
     CDS             complement(44..1657)
                     /locus_tag="OUE31_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCU0223698.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(1798..2706)
                     /locus_tag="OUE31_002750"
     CDS             complement(1798..2706)
                     /locus_tag="OUE31_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCU0223699.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT          868 a          483 c          499 g          926 t
ORIGIN      
        1 aaaaataact cctagaccgc ggctacccac cgcggtcgtt tttttattct tcaatcaaaa
       61 tcgctttgat acccaaacct gccaagattc gggcagaagt ataagtattc aatcctcttc
      121 tgaaagtaat gtaaactttt ttatcttttg ggatttcatt gattcgatct cgtaactcat
      181 tcattggaat attttttgtt gccgagatac tgccagaagg tgctttatta ggttcacgta
      241 tatctaaaaa gaacgcttct ttcaaatcgt tttcgggtat atcacttgct ttgatcgttt
      301 ctacgatatt cgtcatttga ttgattgcga cataaccagc tatattcaac gggtcacggg
      361 tagtagaata cggtggagag taaggcaact ccaaatcagg caaatcaaag actgtcaagt
      421 ttccggtgat tgctacagaa agttctccca tccgtttatc gacacctttt tctccaaatg
      481 cttgtccacc taaaatacga ccgctatctg catcaaaaat cagctttaga tttaatcttg
      541 tagcttctgg atagaaatag gcatggtcaa agggagtgat aaaaacagtt ttataatttg
      601 ttatgcctga tgcttttaat tcatgttctg tcattcccgc ataacttgct gtatgatcaa
      661 agatttttgc gacacctgca ccaatatatc cgcgatagcg cataggcgta ccatttaaaa
      721 tatctgccag catatgtcct tgacgattgg ccgcactgga aagcatactt tggatcggct
      781 gaccagtcac tacactagtc gtttcgataa tatcgccaat cgcatagatg tccggcagat
      841 tggtttgtaa ctggtcatca acaatgatct gacctgtatc tgataattgt atgccggttg
      901 ctttcaccac ttcattcttc ggagaaacac caacagcaaa aattagcata tcagcagaaa
      961 ggacggagcc atctgataat actatttctc gacctttatc acggatctca gtaactcttg
     1021 tttctaaatg aacggctaat ccttctttca gcaatttgtc ataaactaaa ttagcaattt
     1081 ctggatcata agggaaagcg acttgtggca attgatcgat taaagtcacg tctaagccgc
     1141 gatgcttgaa attctcagct aattccagac ccataacacc tgcaccaaga atgacgacat
     1201 gttgtggatt tttttcttca aggaacgatt tgattcgatc cgcatccgtc acactacgga
     1261 ggacaaagcc gttttctgct tcaaaaactc cgggaatatc cggataatct ggtctagcac
     1321 cagaagagat gatcaactta tcgtaatctg tttttatttc ttcatttgtg gataggtctt
     1381 taactgttaa tcgcttagta gaaggatcga ttgctgttac ttcgtgttta gtaaagacat
     1441 cgatgttgtt ttttgttttc aatatttctg gtgtacgttc gatcagcgag tcacggtcag
     1501 tgatcacacc tcctaaataa taaggcaaag cacaacttgc ataagaaata ttttctccgc
     1561 gttcatagat aatgatttcg tgcgcttcat tcaatcgacg gaaacgagtg gcaaatgaag
     1621 gaccgccagc tacaccgcca atgacaacaa ctttcataaa aacatctcct tttctacgtt
     1681 gatcgtacta tgttatggta aaaaacagca aataattgtg ccggaaaatt attgtttatt
     1741 ttgaatagac agaaaatata gagaaataat ttgtggataa aacctaaaaa tttttttcta
     1801 ttttaaggat agataatact ttgaagggga taaccctgta tattttttaa aagctgaaga
     1861 aaaatgatgg atcgaatgaa atcctaatat atctgcaatt tctgtatagg ttaattcatt
     1921 ttctagcacg agacgttttg ctttttccat ttttagttct ttaaaatagc taataacact
     1981 ttttccattc acttttctaa aatgtttttt taagctggct ggactgataa aaaaaatttg
     2041 ggctaattgt tcaagcaaaa aattttctga aagatgttct tctaaatatc gtatgattgg
     2101 atcaactaat tcatctgaat aaagaatatg ctttttttta ggaatgactt tctcatttga
     2161 aggtattgtc aataaagcaa gttcctgttg ataatgcctt ggtaaggaag acaattgaat
     2221 tttttgcaga caataagtaa ctaataagga aagcaaatga atgctcatct gttggcatag
     2281 tatgaaaaaa gaattgattt cctgatcata ggaaatagct ggcttactat gttttagata
     2341 atcaattttg aactgttcat ttttcagaaa agtaatgata gatgttattt cttgatctat
     2401 agaaaaagat tgtcccgtaa tatgtgctaa taattgctca tcaaaataaa actggataat
     2461 gataaaagtt tgtgtttcct tttgagtaga aaagatttgg acttcttgct gtttatcaat
     2521 gaataaaagg gaaggattat ctagttctat agatttatgt gcaaattcag catataaatt
     2581 agcgctttca tttattagta gtcgaaaata gggagcagca gataaatgaa gatgggtatc
     2641 tatggaatag gttagtgttt ttttgacaag attggaggat tggttgtttg ttaacaaaag
     2701 aaccactttc ctttctcttt ttatataaaa agctttctat ttataattaa tgactattat
     2761 aacaaaaatg aaaagc
//
LOCUS       DAKCAA010000139         2732 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000139 DAKCAA010000000
VERSION     DAKCAA010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.143"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..955
                     /locus_tag="OUE31_002751"
     CDS             <1..955
                     /locus_tag="OUE31_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCU0223700.1"
                     /translation="ITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQLGGLLVNHLN
                     GPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPKKKKKKAIITC
                     CYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQLYDVIMIVGTE
                     DPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFSISKIVENLTI
                     LDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKESVDEQEDIEE
                     YMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            968..1600
                     /locus_tag="OUE31_002752"
     CDS             968..1600
                     /locus_tag="OUE31_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCU0223701.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            1805..2032
                     /locus_tag="OUE31_002753"
     CDS             1805..2032
                     /locus_tag="OUE31_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HCU0223702.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            2101..2367
                     /locus_tag="OUE31_002754"
     CDS             2101..2367
                     /locus_tag="OUE31_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCU0223703.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            2357..2626
                     /locus_tag="OUE31_002755"
     CDS             2357..2626
                     /locus_tag="OUE31_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCU0223704.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT          982 a          401 c          554 g          795 t
ORIGIN      
        1 tattacatta gagaaaattg aagcaaaatt gattcaattc cttggagatt atcgaacaga
       61 ttcaggcttg attttattgg tagatatggg ttcactaaac caactaggcg gtttattagt
      121 gaatcatcta aatggaccac tgttaatcat tgatcatatc aatacaccgt tattattgga
      181 agtcggccaa caagtattaa acaataaaag tatcaccgaa ataggagcag aaattgaaac
      241 aagtcttact ttcaaaaagc agttactact tcccaagaaa aagaaaaaga aagccatcat
      301 tacttgttgt tatacaggga ttggtagtgc gacccagatt caggagattt taacgaaatg
      361 cttgaaagat gcagttagag aattagtaat tattccgtat gattacaaaa agctgttaga
      421 aaacaagaat tttgagactc cttttcaatt atacgatgtc atcatgattg taggtacaga
      481 agatcccaaa attaatcaga ttccatatat tggattagat cgcctgatta atgggggaag
      541 cattggcgaa tttgttcatt acttggaaaa agagctgact attgaagtga acgatttaca
      601 aaaagaatta attttcaatt tttcaattag taaaattgtc gaaaatttaa ccattttgga
      661 tccagataag gtgctatctt ttgtacaaaa agcaattaaa gaattatcga agttattaaa
      721 ttttgatttt tctaataatc agctgttttt gttgtacctt cactgtagtt gtatgattga
      781 acgaattgta cgtaaagaaa gtgtggatga gcaagaggac attgaagaat atatgcaagc
      841 aaatggagaa ataatggata aaattcatag cgcttttttt gagattgaaa gggaatacac
      901 aattgaaata ccagatttag agttgcgatt attgagcgat attgttcaag gataggagtg
      961 aattcgaatg acaatgggag taatttttga tatggatggg gtactcatag atagcgagac
     1021 attttatttt gagagaagaa tgaacttctt tcaagaactg gagatagatc caggatcaaa
     1081 ccagattgat gattatgtgg ggaaaacaga agctgcaata tgggaaacat tagttcctga
     1141 ggacaaatca ttaagagagg aactttatcc gaaatatgta gattatcgaa aaacgcatcc
     1201 aattgatttc gctaaagctt tacgaaaaga agtgaaaccg ttacttgact tcctcaagaa
     1261 gcgggatata ccattggcac tggcatcttc ttctccagct gtcgagatag agagtatgct
     1321 cattcaatgt gaacttactg aatatttttc ctttgttata agtggtgagt cattaaaaca
     1381 aagcaaacca catcccgaaa tatatttaaa agcgaaacag caattagact gtgacttctt
     1441 tattgcagta gaggattcaa cgattggtat taaatcagca aaggcagcaa atatctatac
     1501 ggcggcacta aaacaaccaa tgcaaatcga tcagagtgaa gcagacatac aaattgaaag
     1561 tctacaagaa ctggaacaaa ttgttttaga aaaaggttag tgaattaatg gaaataaggc
     1621 tatatatctg tgctagctat tttgactaac caaaaaaact tgctataatt caggtgtagt
     1681 aaaaggtgct ggtaacacct tttacgaaaa tgcttcggca gtgataatgg gattggcttt
     1741 ttaagttttt tattttgttc gcaatcccta aggtcatgtg aatgatccta gggattgcta
     1801 gaatattttg caacagaacc aaaatacgaa tagttatcaa gcagccatat tgactgcggt
     1861 caatttagga ggggatactg atactactgc tgccgtaact ggtgctcttg cgggtattct
     1921 ttacgggggt gaagtgatcc ctgaaaattg gagaaaatcg cttcaaaatg accagcttct
     1981 taaaacgatc agtcagagat tttgcgatac cgtgctatct caaagaattt gaataatgga
     2041 tatgatgcaa atcttgtttg tactaacgtt gtattgacaa aaaggatttt atttagtaca
     2101 atgttagtac aaatgatgaa cggaggtaga atcatgtctc aatcaaccat tacatttagg
     2161 attcccgacg atgaaaaaga actggtatta gaatatgcaa aagcacacaa ttcttcattg
     2221 accgaacttt atcgaaatgc tgtactggat aaaatcgaag atgaaatcga tctacggact
     2281 ttacggagtg caattgaagt ttccaaagag aaaaaagaga gtggtatttc tcaagaggaa
     2341 atggagaaac tgctaaatga attataaagt catctacatg ccgcaagccc agaagcaatt
     2401 aaaaaaaatg gacagaaacc aagctaaaat aattgtcgcc tggatcagaa agaatttaga
     2461 aaacacgact gacccgcgtc agcacggaaa aggtttgact ggaaataaga gtggggaatg
     2521 gcgctatcga attggaaact atcgaatatt ggctaatatt tgtgattctg aaattgaaat
     2581 ccagatattc tcaattggac atagaagtac aatatataaa agataaccgt ttttggaacg
     2641 aagtagagtt tcgaaagtca atgtataatc ttttgaattt tgcataatac cacaggtaga
     2701 aactacccga tactatcggt tggtttctgc tt
//
LOCUS       DAKCAA010000140         2725 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000140 DAKCAA010000000
VERSION     DAKCAA010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.144"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..343
                     /locus_tag="OUE31_002756"
     CDS             <1..343
                     /locus_tag="OUE31_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223705.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSLEQLLSTV"
     gene            618..2513
                     /gene="asnB"
                     /locus_tag="OUE31_002757"
     CDS             618..2513
                     /gene="asnB"
                     /locus_tag="OUE31_002757"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HCU0223706.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT          950 a          449 c          548 g          778 t
ORIGIN      
        1 catcacgaga catgtttggg gagatctgat ggatgaagtg gaacatcttc gcctaacaga
       61 tctgaataaa tcaatttaca aaaaacggaa acaaacgatt gaacgaatat ttgcggatgc
      121 aaaagaaaag catgggatgc gttggaccaa gtatcgaggc ttggaaaaag tcgcgacgca
      181 tacgatgcta gtgtttgctg caatgaattt aaagaaatta gccacctggc tatggaaagg
      241 caaggagcct ttattttttt gttcaaaaat tcgaaacgaa gtagataaaa agctgttcca
      301 agctcgagtt acgagtttgg aacagctttt gtctacagtc tgagacacga tctttaggtc
      361 gtgtcttttt ttgctggttt ttttggaaat agcatccact aatatttttt taacacgaag
      421 agaataaggt agcctcaaaa aagaaaacat ggtaaattag atattgggac tttattttct
      481 gtaaaaacag aaactttcat cttttgtttt cacgtgacga aattgtaaga gagaaaatat
      541 tcgtccgcta tttattctat gataagatgc atatgaatga aataaacagt aattttatat
      601 taggatgtga aagttaaatg tgcggtattg taggttttgt taacgacaag gacaacaaaa
      661 aaacaattat taatacaatg atggatcgaa tcgttcaccg tggacctaat agttcaggag
      721 aatatatcga taaacatgtt gctttaggat tcagaagatt aagtattatt gacttagagg
      781 gcggtactca gcctatttac aatgaagatc ggacaaagat cattattttt aatggcgaaa
      841 tctataatta ccagcctttg agagaagaat tgattgcagc tggccacgtt tttcaaacac
      901 atgcagatac agaagtcctt ttgcatggtt acgaagaatg gggaacagaa ttattgcaaa
      961 agatccgcgg aatgtttgct tttgctattt gggataatga aaagaatgag ttattcggtg
     1021 caagagacca ctttgggatc aaaccatatt attatgcaga aatgaacgga acatttatgt
     1081 ttggttcaga aatcaaaagt tttctgcctc atcctgattt taacaaagaa ttgaacaaag
     1141 aagcgttgaa accttatatg actttccaat attctccatt aaacggcgaa acattcttca
     1201 aagatgtcta tcgtttgcct gaaggccatt attatacgta taaagatgga aaaatagaca
     1261 ttcagcaata ttgggatgca gattttgaaa caaaagaaac gcattcccga caagaatgga
     1321 tcgaaaaaat cgacgaaacc gttcaagctt ctattgaagc acatacggtc agtgatgtag
     1381 aagttggttc tttcttatcc agcggggttg attccagtta tgtaacctct gtattgaaac
     1441 cagatcattc tttctcaatc gggtttgatg ataaaaccta taatgaagcg attgaagcca
     1501 gaaaactaac cgaactattg gacttagata atacagcagc agtgatcgac ggagacatgt
     1561 cgttcaaagc attccctttg atccagtatc acttagatga acctgattca aatccttctt
     1621 gcgtaccttt gtacttttta gcaaatcttg cttcacaaag tgtgcgggta gtccaatctg
     1681 gagaaggggc ggatgaactg tttgcgggat accaaacgta tggattccat acgaattcaa
     1741 aattcatccg tgtgattgct caaggattga aaaaattacc aaaaggaaca cgctataatt
     1801 taggacgtaa aatcggaaaa atgaaaaact tccatggacg gatccattta tatgaatcac
     1861 ttgctcctgc aaaagaatat tttatcggtc atgctcgagt gttcgaagaa tcagaagcat
     1921 cagaagtgtt aacaccaaaa tatcaaacag caccatctgt ggatgaaatc atgactgttc
     1981 attacgagaa aacagaagga atcaaagatg aagtcaataa gatgcaatat gtcgatcttc
     2041 atcaatggat gccaaaagat atcttgttaa aggcagataa actttctatg gcaagttctt
     2101 tggaagtccg agtaccttta ttggatatcg aagtcatgaa attggctcaa caaataccaa
     2161 gtaagttttt attgaatcaa aacaacacaa aagatatttt cagacaagct gcgaacaaac
     2221 atcttccgga agaatggtcg aatcgtgtga aattaggatt ccctgtgcca atcaaagctt
     2281 ggttgaaaga agaacacggc tacgaacaag tcaaagcatt attcgaagca gattttgcaa
     2341 aagaattttt tgatcaagaa aaaatcatga agttgctaga tgaccatcac gaaggacgta
     2401 aagaagagca aagaaaaatc tggacaatct tcagtttctt gacatggtat aaagtctact
     2461 ttgtagatga aacgattccg caagcagaag caatcgacta tgtgactgtt tgatgaaaat
     2521 caaatatcaa taaaaaagag gttttctcct accgtttaac actgagtgat aagaaacaat
     2581 ttcaaaaaac agctcttccc gttttataga tattatgact tatggttcgg agttggcaga
     2641 ggaacaccat tgtttcgaac ataagggggt tgtgacacga ttttcgtcac aaccccttta
     2701 catatgttca ataatcgatt tcttt
//
LOCUS       DAKCAA010000141         2663 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000141 DAKCAA010000000
VERSION     DAKCAA010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.145"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            1..792
                     /locus_tag="OUE31_002758"
     CDS             1..792
                     /locus_tag="OUE31_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCU0223707.1"
                     /translation="MPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFDGFSP
                     FPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYFGSIL
                     GINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISFVLSM
                     IGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILLQLSF
                     IGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            862..1602
                     /locus_tag="OUE31_002759"
     CDS             862..1602
                     /locus_tag="OUE31_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCU0223708.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            1613..2617
                     /locus_tag="OUE31_002760"
     CDS             1613..2617
                     /locus_tag="OUE31_002760"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HCU0223709.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
BASE COUNT          838 a          438 c          544 g          843 t
ORIGIN      
        1 atacctattt ctgaatatcg gaaaaaagca cgagtttctt tggaaaatca atggggaatc
       61 aatacttggc ttgttttctt atctataata tttacgagcg tcatccagaa cttttttgac
      121 ggtttcagtc cttttccgga agaaagcatg cagcagcact tattgagttt tctagtcgat
      181 aatttacttt tattcgcatt caactatgca ttgttttaca ttgcgctagt agttgtacgg
      241 ggtggcagac caaaaagtaa ccttttattt tcagttttcc aaagaaagta ttttggttcg
      301 atacttggca tcaatttgat caattcagtc atcaactggc tactcaacag tttaatcttt
      361 ctgcccatgt ttttaatcag cggagtgagt acttatatgc agctgctttt cagttcaaat
      421 gcggtaccta cgggtgtcat gccagaagat tttcttgata tcagctttgt tttatcgatg
      481 atagggatga tttttgtttc agcactcatc atgagtattg ttggcggttt attccaattt
      541 gctgcatgga caaagttcga ctatcctgat ttgtcggtta ttcaatgttt gaaatatggc
      601 tggtttttat tgaaagatag aattggtacg tatattttgt tgcagctgtc ttttatcggc
      661 tggtatttgc taggagcaat cgctttgttc atcggtcttt tgtgggtcat tgtttatgtg
      721 aatgtgtcag ttgcagaatt ttatgaacaa gcacggattg aaaaaggagg tccagacgcc
      781 tattttactt agcatgtaag cagtttattc atcaaaaaaa taacttttgt ggtaggataa
      841 atctttgagg gggaatgtac gatgaaatta actgttttag gatgcttagg agcgtatcct
      901 tataaaaatc aagggacaac aggttatttg cttcaatctg acgggttcaa tttgttgatc
      961 gatgcaggta gtgctacgct gatcaaatta caagaacacc ttgatccact tgatctagat
     1021 gctgtgatcc ttagccatta tcatcatgat catattgctg accttggtgt attacagtat
     1081 tactggcaac ttcatcctaa gagaaatccg gagacattgc tttcaattta tggacacaca
     1141 aaagattcca ttcactttga agaattgacg ttggaaaatg tctcaaaagg acatccttat
     1201 tttgaagctg aagaattaaa aattggtcct tttctgatta cttttatgga aacaatccat
     1261 ccagtagtat gttacgccat gcgtatcgta gaagaaacaa cggggaaagt attcgtattt
     1321 acaggtgatt caggttattt ggaaagtttc gctgattttg cgaaagatgc tgatttgttt
     1381 ctagcagata cctatctttt tgaaggaaat gaacatcatc atgcccattt cacttcaaaa
     1441 gaagctggag aacttgcgaa atcagctaac gtaaagaaac ttgtacttac acacctacct
     1501 cagtttggtg atttagaaca attgaaaaat gaagcgcaaa aggcagcagg caaagggatt
     1561 gatatagaac ttgctgcagt tgacaaagtg tttaacattt aggaggaaga acatgatttt
     1621 tgtaccaaat gaaaaccacg acccaagaat caatttagca attgaacaat atttgctgca
     1681 agaaatgcct ttagatgaac ctattttgct cttttatatc aatgaacctt caatcatcat
     1741 cggcagaaac caaaatacgc ttgaagaaat caatcgagat tatgtggaag aaaatggcat
     1801 tcatgttgtc cgtcgcttaa gtggaggcgg agctgtctac catgattttg gaaacctgaa
     1861 ctttagtttt atcatgcctg atgatgggga ttcattccgt gactttgcga aagtaacaca
     1921 gccaatcatc caagcacttc atgaattggg tgttgctggg gcggaattga aaggccgaaa
     1981 tgatctagtc attgatggca tgaaattttc tggcaacgcg atgtatgcta ccaacggtcg
     2041 gatgtttgct catggaacaa ttatgttcga ctctgatatc aatgaagtag tcaatgcatt
     2101 aaaagtaaaa aaagacaaaa tcgaatcaaa aggaatcaaa tcgatccgtt ctcgtgtaac
     2161 gaatatcaaa ccatttcttc cagaagaaaa gcaaaaaatg acaacagaag aatttcgtca
     2221 agaaatcttg ttgaaaattt tcggcgtaga gtcagtagaa gaagtaaaaa cgtacgaatt
     2281 gactgatgaa gattggaaaa aaatcaatcg aatctctgag gaatattatc gaaattggga
     2341 ttggaattac gggaagtctc cagatttcaa tttctctcgc caaaaacgtt tttctatcgg
     2401 ttcgattgaa gtccatttga atgtctcaga aggaatgatc aaagaagcaa aaatctttgg
     2461 cgatttcttc ggactaggag atatctctga cgtggaaaaa aaattggttg gacagaaata
     2521 tgataaagca tctctatcaa aaatagtcag ccaaattgat gtgaagaaat attttggtgc
     2581 gatagaacca gaagaattgc ttaccttact ttattgaaaa taaaaaatag cggaatccac
     2641 atatatggat tccgctattt ttt
//
LOCUS       DAKCAA010000142         2568 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000142 DAKCAA010000000
VERSION     DAKCAA010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.146"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(316..516)
                     /locus_tag="OUE31_002761"
     CDS             complement(316..516)
                     /locus_tag="OUE31_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCU0223710.1"
                     /translation="MKINYTVDLVSFSLVINFCLFSLRLFIEGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(821..2054)
                     /locus_tag="OUE31_002762"
                     /pseudo
     CDS             complement(821..2054)
                     /locus_tag="OUE31_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
     gene            2311..>2568
                     /locus_tag="OUE31_002763"
     CDS             2311..>2568
                     /locus_tag="OUE31_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCU0223711.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFN"
BASE COUNT          795 a          487 c          467 g          819 t
ORIGIN      
        1 aatctttgat aaatctattc gaagggtcaa atttaaacca taattgtgtt tttccttcca
       61 tcagcataaa agttcacctc aaaaagagta tacgaacgaa tgttcttttt gtgaaggcgg
      121 aatttaatat actgaataat agaaaacaag tacttgtgcc aaattatgtg ccaaaaaaat
      181 tcgaattcaa caaaatgtaa acaaatagaa aaccttctat attaagattt cctgcaataa
      241 caaacacaac agaagacgtg taatagttag tcaggaacgt acaaataacc cctgtatcct
      301 ttgcggtaca gggggttatt ttgtataagt agacattgta gtttctaaac tgctatgtcc
      361 taaacgtttc gatacgctaa gtatatttac tccttgataa agtaaaatag atgcatgcgt
      421 atgtcttagt ccctcaataa acagtcgaag agaaaatagg caaaaattga ttactaaaga
      481 aaaacttact aggtcgacgg tgtagttgat tttcatactt caacagattc gaattaaacg
      541 atttcgattg gcttatacca gtcctatccg acgaaagata tatcgttctt aactctagcg
      601 gtataacttg aagctttacg taaagccaat gggaatgaac tggagatgac tttttattat
      661 ttttagtaat agctgatggg ttaatactta caactttcct tttcaaagta ccatataaaa
      721 aaacggtggg gttgtttagc gaaataaagg atctaagcca atagcttaga tcctttattc
      781 tatgctttat attatttttt gcatgtgtgc gaaagtatac tcaagcccaa tcgccatttc
      841 ggaaaatcgg tactgtagag ccatcttcac ggattccgtc gatatccatc ttgtcagatc
      901 ctaccatgaa atctacgtgg gtttgacttc tattcaatcc agcttctgct aattcttcat
      961 cggacatttc tgtaccgcct ttcacactga aggcataagc agaacctagt gctaagtgat
     1021 tcgatgcgtt ttcatcaaat aatgtattga aaaagatgat gccagattga gaaataggtg
     1081 aagggtcagg tacaagtgcg acttctccta aacgacgcgc accttcatct gtatcaagca
     1141 gttttgctaa gacatcttct ccttgttcgg cagaaaaatc aatgactttt ccatctttaa
     1201 aagtaaattt catacccgag atgatggtgc cagcataact cagtggcttt gtacttgaaa
     1261 tgtaaccatc tactcgatga ctgtcaggtg ctgtgaacac ttcttccgtc ggcatatttg
     1321 ccatgaattt ttctccacga gcattatagc ttccagcgcc ttcccaaaga tggtttttag
     1381 gcaatccgat aatgatatct gtaccgggag cagtatagtg cagggcagaa aattgttctc
     1441 gattcaattc ttctgctttt tttgctaatt tttcatcatg cttcttccat gctaagacag
     1501 ggtcttcttc atagacacga gtcgttttga aaatctgatc ccataatgcc tcaacttgtt
     1561 tttcttctgg cagttctggg aagacttttg ctgcccattg tttaccagcc gcagccacga
     1621 cagtccaact gactttattt gcttgagttg ccttgcgtaa attcattagt gctttgccag
     1681 ccgctgattg ataagacggc tactcgatgg ctatctacac cagcaaatgc atcgggatcg
     1741 gcagaaacaa cactgatcct gcttgctcct ttttcaagcc attcatccgc ttgatcgatt
     1801 ttagattgtg gtacattctc aatacgatcc gttgcagcat gtaaaagaaa ttctctttgg
     1861 atctggtcgt cagtccattg aacgataacc tcagcggctc ctagtttata agcttcttgt
     1921 gtgatcaatc gagcaagggg tgcctgttcc acgctgatct gtaaaacaac tgtgtgtcct
     1981 ttttctgtgg ctacgccagt ttctgcaatt aagcgtgcat atttttttag aagttcatta
     2041 aaatcagata acataataaa aattcctcct caccattttt tctggtaact attagcatga
     2101 taccatttaa ttatgattca aacaatgagg cctttaaata aaaaaaagag gttatttttt
     2161 taaggttaag tttcatgata tatgttacta cttgctattt cagcttgtga agaaaatcaa
     2221 aaactaattt tgcatatcaa aaaaaacatg ttacaatgaa attaatcaat ggtggaagcg
     2281 ttataaaaaa attaaggaga ttaaaaaaat atggcaagaa aaaagacgat tactagagaa
     2341 cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg atttactgcg
     2401 agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga gtttaaaaat
     2461 atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca atatgaagtg
     2521 ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaat
//
LOCUS       DAKCAA010000143         2484 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000143 DAKCAA010000000
VERSION     DAKCAA010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.147"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(1014..1304)
                     /locus_tag="OUE31_002764"
     CDS             complement(1014..1304)
                     /locus_tag="OUE31_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223712.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2204)
                     /locus_tag="OUE31_002765"
     CDS             complement(1512..2204)
                     /locus_tag="OUE31_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCU0223713.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          734 a          458 c          349 g          943 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgagtttc tacatttgtt
     1681 ttttcttgtg tcagtgttgc gatttgttga ttcaaaccat ttacagtatt ttgtaattct
     1741 gaaagttttg cttgtgcttc ttgtagtctt gctgtccaat ctgcattcag atgattgatt
     1801 tcatcatttt tttggttgat ctcatctagt ttgacattga tttcattttg tttgctttgt
     1861 agttgtgcat ccttgctgac taattgactt tctaagtttt gtttttctgc tgccgattga
     1921 tttttttggt tttctaattc atttactttt gtttggtatt cttggacatc tgcctttgaa
     1981 tcttgcaatg tctgttcttt ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct
     2041 ttatctgtca atgtatgatc aagctgtgtc agattctcat tgattgtatc aatatctgtc
     2101 tctccacccc acaaaataat ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat
     2161 agaaatgcaa cgacaatccc accagtaata aatttctttt tcatttgcat agctccttaa
     2221 tccaatactt ttacatgcta aaagtaagtg atctcaaaca caatgtcaag cgtttttaaa
     2281 ttacatatgt aattttaata taaatactat caaatactca tttaatcctc cttttttatc
     2341 tatttaaaaa atctttttta tagagaaaaa tgcaggttaa tactttctta aataaatatt
     2401 tatggtgaac aaaaacaaaa aagcaagttt tattaaacgt aacccttttc atttcataga
     2461 ttactgtatt tattacaaaa aacg
//
LOCUS       DAKCAA010000144         2333 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000144 DAKCAA010000000
VERSION     DAKCAA010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.148"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(66..1613)
                     /locus_tag="OUE31_002766"
     CDS             complement(66..1613)
                     /locus_tag="OUE31_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HCU0223714.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1715..2068)
                     /gene="tnpB"
                     /locus_tag="OUE31_002767"
     CDS             complement(1715..2068)
                     /gene="tnpB"
                     /locus_tag="OUE31_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HCU0223715.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2058..2252)
                     /locus_tag="OUE31_002768"
     CDS             complement(2058..2252)
                     /locus_tag="OUE31_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223716.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          655 a          484 c          419 g          775 t
ORIGIN      
        1 atagaacagt acctgtacgt caaataaccc gacctataga atagaatcgg gaatgtttgg
       61 cgtttttagt tacgagaaaa atgttgttgt acatccttgt tccaaggcaa cagttgatct
      121 aaagtttctg ctgaaagtac gggaagattt ggtatcttat caaatagaaa ctctagatac
      181 tttacaggat tcaatccgtt aagttctgct gttttatata cactcagaat gattcctgaa
      241 gttcgtgctc cttcaagact tgtggaatgc aaccaatttt tccgtcctat caccagctct
      301 ttgatatttc gctccgcacg attatttgtg agttctaaac gaccatcttc aaaaataggt
      361 tcaaaaccac ttcgtagttt acacgcatat tgaacggctg catccaactt ggattttgca
      421 acaggatcta tcgttgccat ccactcataa aaagcaataa ataatggacg cagttcttgt
      481 tgccgacagc ttaatcgctt ctcaggagaa aagtctttcc atttcttttc taggacaaac
      541 catttatcca attgtttgac tgcttgagct gcgggaatat ccgtgttttt ctttcctttt
      601 ggaattgctt cgaaaaattt ccgccgaaca tgcgcgaaac aatagacaag tcgtacactt
      661 tccacggcat tatacccgct atagccgtca cagtgtaaat accctgtaaa ctccttgaga
      721 aaagttttcg gaacatctcc agcacgactt tcgtcgtggt gataataaac gatgggatgc
      781 tgactgtctt ttcctgtaca aaactgccag taataggtat ctgttttggc actttcaatc
      841 acacgataac ttgtttcatc cccgtgtaga atctcttctt gattaagata gactcttaat
      901 cgttctccta aagggtctaa cgcgttttgc actgctttaa tatgccaatt ggtgatatta
      961 tctctcgaaa tatccaaccc atgtgtttgt ttccaatagt tctcttgccg ataggcagga
     1021 actttctgac caaatttcat ccggatcgtt tccgccacta aactattgga acctaagcta
     1081 ttagaaatca aaggtttagg aacgatcgct tttttaaaag aagaaagtcc ttctttttcg
     1141 cagcttttac aacaataggt atgttgataa tgggtgagac aatccaacat agcctgatgg
     1201 aaacgaattt cttctcgtac ttttgtccgt ccgatatctt tcatctgtga accgcaatgt
     1261 tcacaaaatt gttcttccaa aggaaggaga tgttctttct ctgttatagg taagtgtttg
     1321 attttgtctg ctttcgttcc tacaactcgt tgatgtcctt ttactggaat aatggtggca
     1381 gctgcttctg gaacacttac agaaatttct tcatcactaa aaagattcaa ttgcccattc
     1441 gtttcctcaa agagagtctc tttagagcgt ccaaataatt tgttggttaa ataattgacc
     1501 ttttcattca atagttggat ttcagttgta agattctgaa tggtttgttg ttgtgcttga
     1561 ttggttttat gggcttcttg aagcaactga agcaacgtat ctgtagtttc caaaattttt
     1621 caccaccttg aatcgaactg attttgttac agaataccac aagaaacgca caagaaatag
     1681 gggttcaaca cattttttgt gttaaccccc cagcttaaaa aactcctttt tttcctggca
     1741 aaatagctcg aggttgatcg atacttaatc cttctaacaa ccatcgaacc tgttggttcg
     1801 ttaaggttcg aacttcgtct ttcgtccgag gccattttaa cttgccgttt tctatccgct
     1861 tataacagag aagaaaacca tcaccgtccc aatagagaag tttgaaacgg tcttgacggt
     1921 tcccgcaaaa taaaaaaacg gcatcttcgt aaagctcgag ttgatactct tgttgaataa
     1981 gactggcaag accatcaatt ccttttcgca aatctgtttt tccgcacaca atataaatat
     2041 gtttggtttg aagtaaatca taaagcattg gacaacagtt ctttcaaaat agcttgaaga
     2101 atataattgt taataccgtt atagatcaaa acttcagaac cattctctct tttgatgcgc
     2161 atcgctaact tggcagccgc gggtttacct ttttctggtg cactcttttc gtttcctaat
     2221 tggacaggaa caatctcatt taatttatac atagaaaacc tccagacttc ttgatagctc
     2281 aagtatatct tgaggtgcat ttgttagtaa ggtactgttc tatggggcgc tta
//
LOCUS       DAKCAA010000145         2271 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000145 DAKCAA010000000
VERSION     DAKCAA010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.149"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            192..446
                     /locus_tag="OUE31_002769"
     CDS             192..446
                     /locus_tag="OUE31_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCU0223717.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            447..764
                     /locus_tag="OUE31_002770"
     CDS             447..764
                     /locus_tag="OUE31_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCU0223718.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1323..2258
                     /locus_tag="OUE31_002771"
     CDS             1323..2258
                     /locus_tag="OUE31_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223719.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          430 g          711 t
ORIGIN      
        1 ggatgttaac ggaagtgtat ggtgagtagt tcactcgtat tttgatatcg tttgtatatg
       61 ttttcagcgt tctaagtggc ttattttgtc caataataat atggagtgga atcccttaag
      121 aaacaccgtt ggcaattgtt gttataacat gttataattt attcatcaaa aactaaaagg
      181 agtgtgataa catgggaaaa gaactaaagg ttagaaagat cggcaatagc gtgggagtga
      241 tccttccaag ctctcttgga ttaaaaagcg gagacattat ccaagccaaa caagaaggca
      301 acttattcat attagatact actcaaatag caaaagaaca cgatcgcaaa ttgattgaag
      361 aaagtttcca agactttgag aaaggtttaa cagtttcaga aattgaaatg gtaaaagctt
      421 tcggaaaata cggctggagt gaatagatga aagagtacac gctagtttat tctaaaagtt
      481 ttcagaccag ccttgaaacg ataatagaag aatgggaaaa tgagcttgct ctttctccag
      541 ccagcataaa aagatttgta ggtgcgatcc agaaggcttt agaactaacc aaaaattttc
      601 caactatgca tgaggaagtt tccgaaatct atggaatgga tatcccaaca tatcggatcg
      661 tgatcggcaa aagctatgcc ttattttatc ggatcgacca tgaaaaaaaa gagatacttg
      721 taggacgtat tttccaatct aaacaaatga aactaggctt ttaacaataa ttaggaaaaa
      781 gtcgctcatc ctctacaggt gggtgattaa tgccgctcga tatggttgtt aaccgtcggt
      841 tactcgaaga ttgatatata agacttagta cctttttatt ttgctccatg ttatggccga
      901 aggtctaaag atacaatcat tagtctagag aaaaattaag aaccgtagga actacgggga
      961 tcgcttggtg aataagagac actgctatta gtgaaaaaat aagatatcaa gtacgctcta
     1021 ttcccaaaaa tttcgtgact ttactcatga gaggttcaag tagtatattt ttaatcaaaa
     1081 ttgacgtaac ttttaataaa tactacctaa ataaggtagt atttattttt gtgttttaaa
     1141 agaggaagtc caatatatct atgggaaact tcttaaatat tatgttggta catgaaaata
     1201 tacatccctg ctagactatt tacaacattt tactttgtac gtattcttgt tttaaaagga
     1261 atgggataaa atataggtac aataactatt tgatgctaaa tataattaat ggaggagaga
     1321 tagtgaacat acttaatgaa aaaagatatg tatggtttgc tggtaaaaaa tatattacta
     1381 ctttcaaaag attatccgag ttaatgcagc agactgttaa aagtgctatg cctgaaggat
     1441 acaagtttaa ttttgttcaa tcttcagtat ctactgaaag tatctatttt tcaattcttt
     1501 ctgagagtag gctttttcat tttagaataa gttctcatgt aaagaaaact gatgttgata
     1561 tatatacgtt ccgtacaaat aattataaaa atttaaatga tttgagtaga agtatcagtg
     1621 aatatctcaa ggggaatagc tatctcaaga ttcgattttc acatatatta attttactac
     1681 catatttgaa tgagaatttc accctaattc aagtagataa gtctttcatt gcctcaggta
     1741 atcaaggaaa tatgaatatt acaagtaaca aaacgtcacg tgtgctattg gcgttgatgg
     1801 gttacggaat tctttataga gatgaccaaa atggccagat tctaataaat cgggctgggc
     1861 gttcattatt aatgaaatat agaaaattta taccggaaga ttttcaaaac ttacagttag
     1921 aaaacatgcg tttagaagat ttatttagat tagcagaaga tgataagtat agatttgaag
     1981 ttttgaaaat tcaaaagaat gaactattga ataagttata tcctgagaat gcgataaaag
     2041 cacattttgg tgatgctaat catatgtata gttggttcat tcctaaaaga tttagaggga
     2101 aaatcaatgc tggagatcaa gtgaaagtac tcaatcgaaa tagtacagat gtcgtaatga
     2161 taacagatat ctatgtagaa gatgaagata taatcaaata tatgaagcct gtgataaaac
     2221 ttgttaataa aaataaagga acccgtggtg ctagttaatt ttttcctaga g
//
LOCUS       DAKCAA010000146         2132 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000146 DAKCAA010000000
VERSION     DAKCAA010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.150"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            471..2107
                     /locus_tag="OUE31_002772"
                     /pseudo
     CDS             471..2107
                     /locus_tag="OUE31_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          710 a          322 c          287 g          813 t
ORIGIN      
        1 aactaatcag aatcgtacaa atatttaata accaaatata tagaacataa cttaatatta
       61 agttatttga aattccataa aaaacgactg caggaattat tgtaagaaaa ggataaaaat
      121 agttcagtcc atctccataa ttgttaaatg ttgtatagtt gattggccct tcaaaaatag
      181 aagataaccc tttgattcgt gaaagatgaa aagataaatc acctgttgta taaatttctt
      241 gagcatttct cataaaattt actgaatata aagtactaag taagataaga actactaaaa
      301 gaaatgcttt tttacttatt ttcatagatt tgttgttctc cttttttaat tctattttca
      361 gtatactaga attgtctttt tttaataagt tttgcgttaa atttttcata gcactagtat
      421 gatatactag aaaagaatca atttttatta cttttaaata ggagaaaaaa atgaaaaaaa
      481 acaaaaacca aataatagat atcattttta tgttatttct aagttttgct tacgtcatcc
      541 ctctattcat gtctatggga atctatcata gtgtcaatca ggatacttac tttcatttat
      601 ctcgaatcat aggactagat aatgtatgga gttctccagt aaacttcaat aacttcgatc
      661 atcatggaac aatgatgaat attttttatc catggcttac tctttatcca gcttttttat
      721 tttataaaat gatgggaaat cttgttttaa gttataatat ctactatttt tttatcactt
      781 ttttaacaat ggtcgtttct tatttttcta tgaaacaaat aaaaaacaat cgttatattt
      841 cgctgttatt ttcgattatt tatacatttt ccgcctatcg tgccattgac atattccatc
      901 gtgcttcatt gggagaagct gtcgctttaa catttttgcc tttgatacta atggggtgtt
      961 acgaaattta tattagagat taccaaaaat ggtactggtt gtctattggc atgacgctag
     1021 tagtgtatac tcatttactt tctgtcgcta tggtttctgt atttattgga ggaacgttgt
     1081 ttctttcttt ttatttttgg gaccaaaaaa tcgctagact cttaagtctt ttaaaagcta
     1141 ccgtcctcac ctttttttta agtgcgggat tcttaattcc ttttattcaa caatctagag
     1201 cacaagaatt gaaagtccca ctgggaaaag aattaagtgg tatggctcct agtgatatgc
     1261 tgacacacat tttaaataat aactataaca actatactat tggattattc ttatttctcg
     1321 gattgattgg tgcttttatt tttataaaaa aattaactgc tgatgattta tttattttct
     1381 ttcttggtgt atttgttctt ttttgttcaa ccaatttatt tccttggcaa ctttttaacc
     1441 atacaccagt taagagtcta caatttgtct ggcggttaaa tggttttctt ctttatttat
     1501 agcctatacg atgagtatag tgatctatta tattttttct actaaaaata attcatggaa
     1561 aataatggtc tttacgtttc ttgcactaat attgcatctc tcaggagtaa gcaattctat
     1621 ccatgctaac aaagattcat taacacttat agcacctgaa gacgctgttg ctatagctga
     1681 aaattacaat catactgatt atgcaaacaa agagtcaatc tatcatcctg atatgattaa
     1741 taatgatcaa tatttactag gtaaccagga aataaatcca acaactcatt ttatgagtaa
     1801 caaacttaca attgaattag ataattcgaa taataaaaat actgtcttga cgacacctat
     1861 ttatcgttat aaagggcaag tggcttctat taatggcaaa ctagtacaaa caaaattatc
     1921 taagtttggc acaactgaat taactattcc tccaggtata aataaagtcg ttattactta
     1981 tcagtacaca aaactagcaa ttgcttcaag atatttatct atcgttactt tgattttatt
     2041 tttactttat cgatttactt tttctaaaca aaaacaaccg agaagagaag tacaacattc
     2101 tcactagatt tttatttaag aaagactttt ta
//
LOCUS       DAKCAA010000147         2103 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000147 DAKCAA010000000
VERSION     DAKCAA010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2103
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.151"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(483..556)
                     /locus_tag="OUE31_002773"
     tRNA            complement(483..556)
                     /locus_tag="OUE31_002773"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(520..522),aa:Ile,seq:cat)
     gene            complement(745..1764)
                     /locus_tag="OUE31_002774"
     CDS             complement(745..1764)
                     /locus_tag="OUE31_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HCU0223720.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1775..1981)
                     /locus_tag="OUE31_002775"
     CDS             complement(1775..1981)
                     /locus_tag="OUE31_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCU0223721.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          629 a          416 c          347 g          711 t
ORIGIN      
        1 gaattttatc accatacttg tgaaaggaga tattttttaa gttagtatta agattgtgta
       61 atatgatgat atctatattt tatagtatca gtgctataaa atcaaaaata agtcactaat
      121 taactaccac tccaattgta agcctttttt ctcacttttt ttcaaaaata tggtatgcct
      181 tttaatagct tcaaatataa aagagtttaa agcgtaacac acttatgggg aagtggcttg
      241 gggtgcgctt taaactcttc tttattatca tctcacaatt taacccaaat gtctttctat
      301 ttaaaaatca aagtaaaact tttcaaatat acagaaatat aactatgtga aacatccttt
      361 cattaatcca taaaaggata cataaaaaag ccactcattt gagtggcaat gaagaaaagc
      421 tttagcttgt ataatactct tcaaaaaatt ctaacacaga acgattcaaa tggctacgtt
      481 aatgtaccct gtaggactcg aacctacgac cggacggtta tgagccgtct gctctgacca
      541 actgagctaa gggtactggt tgttgccaca taaagccata aacaatcaac cagtagaatg
      601 tgtggcaaca aacctgttat cgcatagctt ggagtgtgac tattatgggt gatagtgaag
      661 atatgcgata acatcactat tttatcgaat gatttttata gttgtcaata tagttatgta
      721 atgctcctca acgaggagct atttttatcg tttaggaata tttaaatacc aacgtttgtc
      781 atggaaatct tgcgcaccgc ctttagtgtt tccctctgga tcattcgttg cccgcatcat
      841 gacatagact ttcttattag ggaagttacg catgttaaaa gatacatgat agccaacatt
      901 tccagaagta ttataagctt gatttacatc tgatctataa attccatcag ctcttactcg
      961 agctaattct ttcccagtat tgtaatccat aatgaagata tactcgtatt tatagttagc
     1021 aatgtgccat ccagctacat gcaaatttgc attttcgatt tctccaaact gatcaatgtg
     1081 ggcgtaattc gttccatctg tcagtgtagg attagctgca ccagctcgtg ttggatcaat
     1141 gacaggcttg ttttcagaag ttgttggatt ttcatcggta aatccatgag ctaaatcata
     1201 tgctaatttt tctttactta cgcccatttc agaaagataa ccgtaaggat ctgtatgatc
     1261 gccccagatg ttttgtgtta cccataaatg cgatttgatt cccggttggt tataaggagt
     1321 gtccaacgtt aatggaatac catatttcat tgctgaatct ctagccaatt caacgtatgc
     1381 cttgtagttt ttctcaaacg ttgctttatc atgtgtgtgt tgtaactcaa tctgcacagg
     1441 actgttggca ttagcatacg aaccagcacc gtactgtaca taaccaggtt gaccgacttg
     1501 ataaacaatt ccgccgtctc ccacaatata agcagtataa gcgctagtcc atgaacgttg
     1561 catatactgc gcttcattgc gtcctgttgc tgtttcatta gccgtttcat gcagtaaaat
     1621 atactgatta tttgctactt gtgagctacc ttcatttgcg cccaaattaa attcattgtt
     1681 gatagtatag gcaaatccgt taattggcaa taaaaaaaga gccgttaaca ggctcatcgc
     1741 agtaatagta attttctttt tcatatctat cctcctattt atctgatgaa attttcttat
     1801 acgttcgatt tgatacacct aaaatactcc ctagaaatgc tccaaaacct gtaataatca
     1861 tcaccgttat atctgtgtac cgccagttaa caccttttcc gacaagaccg acaaaagtcg
     1921 ctaaagcggg gataactact atagcgatcc atttcaaaat atcaaaggtt ctattgttca
     1981 tactatccac ctcccttcat tggttgggct actttctttt tcaatcgctt gttttcttct
     2041 atcaatattt ctctttctga aagcaaggca tcaatttgcc cgtccagttg ttcaatttta
     2101 tct
//
LOCUS       DAKCAA010000148         1948 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000148 DAKCAA010000000
VERSION     DAKCAA010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.152"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            181..483
                     /locus_tag="OUE31_002776"
     CDS             181..483
                     /locus_tag="OUE31_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223722.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(999..1072)
                     /locus_tag="OUE31_002777"
     tRNA            complement(999..1072)
                     /locus_tag="OUE31_002777"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1036..1038),aa:Ile,seq:cat)
     gene            complement(1627..1941)
                     /locus_tag="OUE31_002778"
     CDS             complement(1627..1941)
                     /locus_tag="OUE31_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223723.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          708 a          289 c          301 g          650 t
ORIGIN      
        1 ttttataagg gtttgagcat tttttatttt cgcagatttt cgttaaatga atgaaaatgg
       61 cattcaaaat agcattcaaa aagaacactt tttaatatat atgttccatc catattatca
      121 atgatattcc tactttacaa aaagaacatt agttcgtata ctctttttga ggtgaacatt
      181 atgttgatgg aaggaaaaac acaattatgg tttaaatttg atccttcgaa tagatttgtc
      241 aaagattttt ataaggtgtg ggattcagaa gttttctttt tagcaatcga agatagctta
      301 ttaatcaatc tctattactc taataagaac tactttaaaa ttccggcaac aaaaaccaga
      361 atgaagaaag atgtgtattt tttgtttgat atcgtgactg atgtgccaga cgcacggagc
      421 gatcatcggc gttatgacta tttgaagtat actttcgttg atccagaaag gtataaagat
      481 taaagtaggc tacctaaaaa aggtagcccg gaacggattt tatcaccata cttataaaag
      541 ggatattttt taagttagta ttaagattgt gtaatatgat gatatctata ttttatagta
      601 tcagtgctat aaaatcaaaa ataagtcact aattaactac cactccaatt ataagtcttt
      661 ttcccattat tttttacagt tatatggtat gctttttaat ggcttcaaat ataaaagagt
      721 ttaaagcgta acacacttat ggggaagtgg tttttgggga acgctttaaa ctcttcttta
      781 ttattatctc acaatataac ccaaatgtct ttccatttaa aaatcaaagt aaaacttttc
      841 aaatatacag aagtataact atgtgaaaca tcctttcatt aatccataaa aggatacata
      901 aaaaagccac tcatttgagt ggcaatgaag aaaagcttta gcttgtataa tactcttcaa
      961 aaaattctaa cacagaacga ttcaattggc tacattaatg taccctgtag gactcgaacc
     1021 tacgaccgga cggttatgag ccgtctgctc tgaccaactg agctaagggt agtggttgtt
     1081 gccacataaa gccataaaca atcaaccagt agaatgcgtg gcaacaaacc tgttatcgca
     1141 tatcttggag tgtgactatt tatgagtgat agtgaagata tgcgtctcca tatatgtatg
     1201 gttgagacag ataaacatgt atgaaaaacg ttgttaaatc aacgtttttt tattttggtc
     1261 aaggagagaa aagtagagaa atacaaaatt ttttgcattg attttgcatt caaaaaaaca
     1321 ttcaaacatt tagaaatccc caatacgtat tcaggaaaat ctattttaag gtttacaaaa
     1381 agaacttttg ttcgtacact ctttttgagg tgaactttta tgctgatgga aggaaaaaca
     1441 caattatggt ttaagcatgt tccttcaaat aagtttttta attataaact ctagagaaat
     1501 taattcatcc taacataaaa taattgttca ctcaaaagtt tttctagaac aattaaaaca
     1561 gcaggcttca cattcgctat acatttgtaa gaagtaataa ttcctgtact aaaaggcata
     1621 attgctttaa ttattttttg acttctcttc aaacacaaga agtagttgtg taataattgc
     1681 agaaataagg attccaataa tagatataaa atttgacatg gaaacgtcta taacattaaa
     1741 agaataaagt gttgaagaaa gtaaactgat tgaaataacc cctccgtaaa aaatagtctg
     1801 tgaatatacc cacttttttt cagaagacgt acttcgtttg gttctaaaac ctatccctgc
     1861 atttctactc ttatcaaaaa accaaatatt tagaagtaat aatattgcta ttattaagat
     1921 aaaattactg taaaaatcca aaagctat
//
LOCUS       DAKCAA010000149         1941 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000149 DAKCAA010000000
VERSION     DAKCAA010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.153"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(44..220)
                     /locus_tag="OUE31_002779"
     CDS             complement(44..220)
                     /locus_tag="OUE31_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCU0223724.1"
                     /translation="MKEFIEKYKYPLIFACVGLLLGLLILTLGLFKIVIITILTVCGF
                     YLGIYLETIGFFDK"
     gene            complement(230..790)
                     /gene="amaP"
                     /locus_tag="OUE31_002780"
     CDS             complement(230..790)
                     /gene="amaP"
                     /locus_tag="OUE31_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCU0223725.1"
                     /translation="MRKSLKLLLTIVLLLFFFPLAHTLITMQSVVSLPFYLLPFTSYP
                     YIGNNMAQFLFWLSAVLLTFLFIILIIVLFYPRINNYIEKKTDTGKIAIQKKAIENFV
                     LIAAKEEPFIVDPTVKVVIKKKKIKIYVRGKIRKAFQTGERQTSFIRKVNTNLNALFG
                     AEQTILTEIKFNDYHERNKETKSKVL"
     gene            complement(1736..>1941)
                     /locus_tag="OUE31_002781"
     CDS             complement(1736..>1941)
                     /locus_tag="OUE31_002781"
                     /inference="COORDINATES: protein motif:HMM:TIGR01167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCU0223726.1"
                     /translation="PETPVTPETSNYKTLQIQKSKVNYKSETNKTLPKTGEAKSSGVF
                     VGIIVLLTSIFAGFKLNLKRKKG"
BASE COUNT          676 a          286 c          211 g          768 t
ORIGIN      
        1 ataaaaattt attttttacc gtaaaaacgg ttattaacta gttttatttg tcaaaaaatc
       61 caatagtttc taaatagata cctaaataaa aaccacatac agtaagtatt gttattatca
      121 ctattttaaa aagtcctaac gtgagaatta ataatcctaa tagtagtcct acacatgcaa
      181 aaatgagcgg atatttatat ttctctatga attctttcat tgttttctcc tataaaactt
      241 ttgatttggt ttctttattt ctttcatgat aatcattgaa ttttatttca gttagtattg
      301 tttgttctgc accaaataag gcattcaaat tagtgtttac tttccttata aaggaggttt
      361 gtcgctcccc tgtttgaaaa gctttacgta tttttccccg tacatagatt tttatttttt
      421 tcttcttaat tacaactttt accgttggat caacaataaa aggctcttct tttgctgcga
      481 ttaatacaaa attctcaatt gctttttttt gaattgctat ttttccagta tcggtctttt
      541 tttctatata attatttatc ctaggataaa ataatacaat aattaaaata ataaataaga
      601 atgttagcaa aacggcacta agccaaaaca aaaattgagc catgttatta ccaatatatg
      661 ggtaacttgt aaatggtagt aaataaaatg gtaaactaac cacactttgc attgtaatta
      721 acgtatgtgc taaaggaaaa aaaaacagca gtaaaacaat agttaatagt agtttcaagc
      781 tttttcgcat attccacctc ttagattacg ttgtgaatat aattctttat tttattattc
      841 tatggaactt tacaattaaa caaaacctat aaattaaact tgacacagat tttggcagtt
      901 tgatttctag aatattctcc tttcatttca tttatctcac taactttagt taaactaata
      961 cgataagttt aaccaattac tatatctgaa actatcaaag tgagtaactt gtataaaaaa
     1021 atagactgtt cactttataa attaaaatag tttacgatat aatattatca agtaaaaatc
     1081 ctcaagtcaa ataaaaatga atgttcaatt tattttttat acaagttttt taattctaga
     1141 aataagttcc ctgcttataa gaagatgtac taaataatga ttcttatctc acaaacatat
     1201 tatttcttac ctccaatcct tttagaaacc ataaaaacta ttaactaaca atatttgaaa
     1261 attcacacta gtattattta atccactaga caaaaaatta ctatcatcga tataaaaaat
     1321 ttttttcgat tgtatataat attttttttg agagatgaga tttttctatt gaaaatttct
     1381 tatcttccaa tgtttttttt gttaaagaag acttaatttt tcgtttttta tttcctgttt
     1441 ctttaattac aagtctttgt ccctagaaaa aataaaaaat caaccaataa gtatttctga
     1501 ataatgaata atataatacg ttttttcggc caagcatatt aaacattggg cgtgagattc
     1561 agtatcttga atatacttat gatttaaata gactcttttc ttatacattt cttgcctaaa
     1621 gattatatat atttctcttc taaagttatc ataatccctc cttaatactt gagtgatata
     1681 aaacataatt acaacctgag atagaacact aagtattcta tctcagatct attttctatc
     1741 ctttttttct tttcaaattt aatttaaatc cagcaaaaat agaagtcaat aaaactatta
     1801 tacctacaaa tactccagat gattttgcct ctccagtttt tggaagagtt ttatttgttt
     1861 cagatttata attcacctta ctcttttgta tttgtagagt tttataatta ctagtctctg
     1921 gcgttaccgg ggtttctgga t
//
LOCUS       DAKCAA010000150         1933 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000150 DAKCAA010000000
VERSION     DAKCAA010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.154"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..245)
                     /locus_tag="OUE31_002782"
     CDS             complement(<1..245)
                     /locus_tag="OUE31_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCU0223727.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQ"
     gene            483..1652
                     /locus_tag="OUE31_002783"
     CDS             483..1652
                     /locus_tag="OUE31_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCU0223728.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          687 a          323 c          300 g          623 t
ORIGIN      
        1 tcttgccata cctcctgaat ttgaccatca ggagtcgtaa tgaaaatagt atcattttca
       61 tctactaatt ctcttaagtt taaatattgt ttactagatg taaaattcga agctgctaat
      121 gacgagtctt cgcttttact ataaaatcct gttacttgta ttttatgttc ctggaaatac
      181 ttcccgaatg aacaacctac cttgccggct ccaataaaac caacgttcat aattatcacc
      241 tccataaaga agtgagacta caagtcccat tcttacgata tgagcttaaa aataaaaatt
      301 aaatcaaata tacagtatgt ttttttcaaa tatcatccat agttaattta tcataatatc
      361 ccatatttta aaataaaaga tagcgtaaaa tattttgtgt aaatagaaat ttagggtaga
      421 aaaaaaagtc cattctgtaa aattaaagtt accacacaga aattttatag gaggactttc
      481 tcatgactaa atttactata gaaattatgc aaacactact caataaaggg gatttagatg
      541 aattatttca ggatcattta gagcgagcga ttaattcact tctacaagca gagctaactg
      601 cttttttaga ttacgaaaaa tatgatcgaa atggattcaa ttcaggaaat tcccgtaacg
      661 ggaattattc acgtacattt aaaacagaat atggcgagtt gaatttaact attcctagag
      721 atcggaatgg cgaattttct caacaaacac taccagcata taagcgaacc aatgattcat
      781 tagaaacgac cattatccaa ttatttcaaa aaggcattac tatggctgaa atctccaaat
      841 taattgaaaa aatgtatggt caccactata cgccacaaac aatctccaac atgagtaaat
      901 tggtggctga agatgtttta gcttttaaag aaagaacgtt agaagccaat tattccgtta
      961 tatttatgga tgcgacgcat atccctgtga agcgacagac tgtttcgaag gaagcagtgt
     1021 atattacgat tggtattcgt ttggatggaa ccaaagaagt tcttgggttt actattgccc
     1081 caactgagtc tgcttatatt tggaaagaag ttcttcaaga tcttagaaaa cgtgggttag
     1141 aagaagtttt attagtagtg acagacggat taagctgtat tgaagaaagt atccatagtg
     1201 tgtatccgaa tgcccaattt caacaatgtt gtgtgcatgt atctagaaat atcgctcata
     1261 aagttcgtgt tcgaggtcga aaagaaattt gtgaggattt caaattggtt taccaagcga
     1321 attcaaaaga agaggcattg gatcacatcg actttatgac taggaaatgg aaaaagcagt
     1381 atccaagagt cgtcaattta ctcttgaatc ctgccctatt aaccttttat aatttccctc
     1441 acgccatcag acgaacaatt tattcgacga acctgattga aggctttaat aagcagctaa
     1501 aacgatatac tcgaagaaaa gaacaattcc ctaatgaaga atctctagag agattcttca
     1561 tttctcaatt taatcaatat aaccaaaaat ttttaggtag aattcacaag ggatttaaag
     1621 aaattcagga tacattagag tcgatgattt aactgtaatt aacagaatgg attttccatt
     1681 tacatataat tcttgacgct accataatct aaataaccat catattcatc tactacttat
     1741 ataattgagt tttattaaac tttttaagtt tctattctat caaatattta aacaatctct
     1801 gcatccgaaa agactacctc gtatagtttt actaacaata tttttattag cgtgttcaaa
     1861 tcctgatttc ttgtatcaat tattttctgt tcactttcaa taagaaaaaa gtctttactt
     1921 ccatggataa taa
//
LOCUS       DAKCAA010000151         1931 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000151 DAKCAA010000000
VERSION     DAKCAA010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.155"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..435
                     /locus_tag="OUE31_002784"
     CDS             <1..435
                     /locus_tag="OUE31_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HCU0223729.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="OUE31_002785"
     tRNA            complement(759..842)
                     /locus_tag="OUE31_002785"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="OUE31_002786"
     CDS             1370..1870
                     /locus_tag="OUE31_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0223730.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
BASE COUNT          625 a          364 c          329 g          613 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat t
//
LOCUS       DAKCAA010000152         1766 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000152 DAKCAA010000000
VERSION     DAKCAA010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.156"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(140..211)
                     /locus_tag="OUE31_002787"
     tRNA            complement(140..211)
                     /locus_tag="OUE31_002787"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(176..178),aa:Glu,seq:ttc)
     gene            complement(223..296)
                     /locus_tag="OUE31_002788"
     tRNA            complement(223..296)
                     /locus_tag="OUE31_002788"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(260..262),aa:Ile,seq:gat)
     gene            complement(309..379)
                     /locus_tag="OUE31_002789"
     tRNA            complement(309..379)
                     /locus_tag="OUE31_002789"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(345..347),aa:Gly,seq:tcc)
     gene            complement(384..456)
                     /locus_tag="OUE31_002790"
     tRNA            complement(384..456)
                     /locus_tag="OUE31_002790"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Phe,seq:gaa)
     gene            complement(460..532)
                     /locus_tag="OUE31_002791"
     tRNA            complement(460..532)
                     /locus_tag="OUE31_002791"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(497..499),aa:Asp,seq:gtc)
     gene            complement(551..624)
                     /locus_tag="OUE31_002792"
     tRNA            complement(551..624)
                     /locus_tag="OUE31_002792"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(588..590),aa:Met,seq:cat)
     gene            complement(637..726)
                     /locus_tag="OUE31_002793"
     tRNA            complement(637..726)
                     /locus_tag="OUE31_002793"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(688..690),aa:Ser,seq:tga)
     gene            complement(749..820)
                     /locus_tag="OUE31_002794"
     tRNA            complement(749..820)
                     /locus_tag="OUE31_002794"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(785..787),aa:Glu,seq:ttc)
     gene            complement(842..929)
                     /locus_tag="OUE31_002795"
     tRNA            complement(842..929)
                     /locus_tag="OUE31_002795"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(893..895),aa:Ser,seq:gct)
     gene            complement(954..1027)
                     /locus_tag="OUE31_002796"
     tRNA            complement(954..1027)
                     /locus_tag="OUE31_002796"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(991..993),aa:Ile,seq:gat)
     gene            complement(1041..1111)
                     /locus_tag="OUE31_002797"
     tRNA            complement(1041..1111)
                     /locus_tag="OUE31_002797"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1077..1079),aa:Gly,seq:tcc)
     gene            complement(1113..1188)
                     /locus_tag="OUE31_002798"
     tRNA            complement(1113..1188)
                     /locus_tag="OUE31_002798"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1153..1155),aa:Asp,seq:gtc)
     gene            complement(1207..1280)
                     /locus_tag="OUE31_002799"
     tRNA            complement(1207..1280)
                     /locus_tag="OUE31_002799"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1244..1246),aa:Met,seq:cat)
     gene            complement(1293..1382)
                     /locus_tag="OUE31_002800"
     tRNA            complement(1293..1382)
                     /locus_tag="OUE31_002800"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1344..1346),aa:Ser,seq:tga)
     gene            complement(1406..1479)
                     /locus_tag="OUE31_002801"
     tRNA            complement(1406..1479)
                     /locus_tag="OUE31_002801"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1443..1445),aa:Ile,seq:cat)
     gene            complement(1493..1566)
                     /locus_tag="OUE31_002802"
     tRNA            complement(1493..1566)
                     /locus_tag="OUE31_002802"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1530..1532),aa:Met,seq:cat)
     gene            complement(1594..1666)
                     /locus_tag="OUE31_002803"
     tRNA            complement(1594..1666)
                     /locus_tag="OUE31_002803"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1631..1633),aa:Ala,seq:tgc)
     gene            complement(1686..1759)
                     /locus_tag="OUE31_002804"
     tRNA            complement(1686..1759)
                     /locus_tag="OUE31_002804"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1723..1725),aa:Pro,seq:tgg)
BASE COUNT          503 a          472 c          402 g          389 t
ORIGIN      
        1 gcttaaaaaa tataaaaata ttttacatta gaactgtcca aaaaagctta gcacaatcat
       61 ccataaagat aactctgcta agctttttaa aatcattctt tcagataaaa agaaaaagat
      121 actcaaaaag tatcttccat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
      181 ggcggtgtct taaccgcttg accaacgggc caataaaata aatgggccta aatggactcg
      241 aaccatcgac ctcacgctta tcaggcgtgc gctctaacca gctgagctat aggcccataa
      301 aaactaaaag cgggtgacga gaatcgaact cgcgacaaca gcttggaagg ctgtggtttt
      361 accactaaac tacacccgca taatggcgcg ggacagaatc gaactgccga cacatggagc
      421 ttcaatccat tgctctacca actgagctac cgagccaaac ggttccgacg ggaatcgaac
      481 ccgcgatctc ctgcgtgaca ggcaggcatg ttaaccccta caccacggaa ccaatgtttt
      541 tagtttttaa ttgcgggagc aggatttgaa cctacgacct tcgggttatg agcccgacga
      601 gctaccagac tgctccatcc cgcgataata tgaaaaagga ggataaggga ttcgaaccct
      661 tgcacggttt tacccgcctg acggttttca agaccgttcc cttcagccgg acttgggtaa
      721 tcctccatgt aaaactatat taaattaatg acccgtacgg gattcgaacc cgtgttaccg
      781 ccgtgaaagg gcggtgtctt aaccgcttga ccaacgggcc aggtaaaaca aaatattgaa
      841 acggagaagg agggatttga accctcgcgc cggtttcccg acctacaccc ttagcagggg
      901 cgcctcttca gccacttgag tacttcccca aaaccaataa gattttgtac taatgggcct
      961 aaatggactc gaaccatcga cctcacgctt atcaggcgtg cgctctaacc agctgagcta
     1021 taggcccata aaaaactaaa agcgggtgac gagaatcgaa ctcgcgacaa cagcttggaa
     1081 ggctgtggtt ttaccactaa actacacccg catggcggtt ccgacgggaa tcgaacccgc
     1141 gatctcctgc gtgacaggca ggcatgttaa cccctacacc acggaaccag tgtttttagt
     1201 ttttaattgc gggagcagga tttgaaccta cgaccttcgg gttatgagcc cgacgagcta
     1261 ccagactgct ccatcccgcg ataatatgaa aaaggaggat aagggattcg aacccttgca
     1321 cggttttacc cgcctgacgg ttttcaagac cgttcccttc agccggactt gggtaatcct
     1381 ccatatgaaa cttacaacgc cacaatggac cttgtaggac tcgaacctac gaccggacgg
     1441 ttatgagccg tctgctctaa ccaactgagc taaaggtcca ggctcttaaa aatcgcggcg
     1501 gaggggatcg aacccccgac ctcccgggta tgaaccggac gctctagcca gctgagctac
     1561 accgcgaaaa agatattcat tatttaaatg aaatggagcc tagcgggatc gaaccgctga
     1621 cctcctgcgt gcaaagcagg cgctctccca gctgagctaa ggccccgtgt ttaaatttat
     1681 aattatcggg aagacaggat tcgaacctgc gaccccttgg tcccaaacca agtgctctac
     1741 caagctgagc tacttcccgt ttaatt
//
LOCUS       DAKCAA010000153         1743 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000153 DAKCAA010000000
VERSION     DAKCAA010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.157"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            64..237
                     /locus_tag="OUE31_002805"
     CDS             64..237
                     /locus_tag="OUE31_002805"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223731.1"
                     /translation="MCCGNSILLKGLPFFYLHKIFYTLGLKERGLSGVKMVISDAHIG
                     LTKAVKEYLLCAS"
     gene            268..669
                     /locus_tag="OUE31_002806"
     CDS             268..669
                     /locus_tag="OUE31_002806"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223732.1"
                     /translation="MSDKFSKKISSDIKEDFKAIFKTASIELAGERKQLIMDKYGEDK
                     KVATACKILDEGFEDAMQVMVLPENIRQRLRTTNVLERLNEEVRRRERVVRIFPNCDS
                     VIRIIGALLMEKDDEWTSAPRKYLEFDRNEI"
     gene            complement(876..1376)
                     /locus_tag="OUE31_002807"
     CDS             complement(876..1376)
                     /locus_tag="OUE31_002807"
                     /inference="COORDINATES: protein motif:HMM:NF012385.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCU0223733.1"
                     /translation="MQQNRLKEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIY
                     EYAKEQQVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLM
                     GIEFSNNQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKF
                     ESTVIK"
     gene            1438..1743
                     /locus_tag="OUE31_002808"
                     /pseudo
     CDS             1438..1743
                     /locus_tag="OUE31_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          537 a          316 c          332 g          558 t
ORIGIN      
        1 ttcgctagag tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg
       61 tgaatgtgtt gtggtaactc tattctactg aagggacttc cttttttcta tttacacaaa
      121 atattttaca ctctcggatt gaaagaacgc ggtctttcag gagtaaagat ggtcatctcg
      181 gatgcgcata tagggctcac aaaagctgtg aaagaatacc ttctttgtgc gagctagcag
      241 agatgccaag cacatctcct tcgcaacatt tccgacaaat tctccaagaa aatctcaagc
      301 gatatcaaag aagactttaa agccatcttc aaaacggcaa gcatcgagct ggctggagaa
      361 cgtaaacaac ttattatgga taaatatggg gaagacaaga aagtcgcaac tgcctgtaaa
      421 atattggatg agggcttcga agatgccatg caagtaatgg ttttaccaga aaatatccgt
      481 caacgattga gaacaacgaa tgttcttgaa agactaaatg aagaagtacg ccgtcgtgaa
      541 cgtgttgtcc gaattttccc aaattgtgat tctgttattc gtatcatcgg tgctttattg
      601 atggaaaagg atgacgaatg gacttctgca cctagaaaat atcttgaatt tgatcgtaac
      661 gagatttagc acattaagcc gccaatagta taatatactg gtgagaagta tcaagagacg
      721 cttcgctttt tgctcttgac acttcttacc agcatattgg accgtagcta ggctcaacaa
      781 ggcaaaacat cgtactttga gatttccttt ttacacaaga ttttggactt gacacagccc
      841 ctatggttct taccttgttt atgcttattt aaatcttact ttattacagt actttcaaac
      901 ttcgttttgt aagccgggta ttttgatatt tcataattat gtccctcttt ttgaatatat
      961 tctttgatat ctgcttgttc atctacactt tctttgcgta aaatacgttc gatcattgag
     1021 cagcagtgca tgtaaagcaa gaacaattga ttgtttgaaa attcgatccc cattagtttt
     1081 tcgagttctt tgacggcctt ttgtaccaat ctcaaaacct tcattgcatc aaggatcgtt
     1141 aaattttcta cgatcttgtt aatcgagaaa ttaaagtatt gagcacaatt ataggcgata
     1201 aatggagcat ttgattctat cacctgttgt tccttggcgt attcataaat tttttctgcc
     1261 aaaaaggttt ttcctgaacc gcttacaccc atcaataaaa tcggtaatcc gttatgagga
     1321 tacaagacag ccgtcttgat ttgatcgatc gcttccttta aacggttctg ttgcaaagtt
     1381 ttaaatctac tatcaaataa ggtagaataa tagaaaaaga tagcaggagg aatgacgatg
     1441 aatcatttta aaggaaagca atttcagcag gatgtgatta ttgtagccgt gggctactat
     1501 cttcgttata accttagcta tcgtgaagtt caagaaatct tatatgatcg tggcattaac
     1561 gtttctcata cgacgattta tcgttgggtg caagaatatg gcaaactact ctatcaaatt
     1621 tggaaaaaga aaaataaaaa atccttttat tcatggaaaa tggcattatt tgtatcgagc
     1681 catcgatgca gatggtttaa ccttggatat ttggttacgt aaaaaacggg acacacaagc
     1741 agc
//
LOCUS       DAKCAA010000154         1732 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000154 DAKCAA010000000
VERSION     DAKCAA010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.158"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            361..1611
                     /locus_tag="OUE31_002809"
     CDS             361..1611
                     /locus_tag="OUE31_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCU0223734.1"
                     /translation="MKLFIGLDVSSQKLDTCFLTDSKEILFEGSLSNDLIGASEIKQR
                     ILDYQETFGFCRIVIGMESTSVYSFHPAMFFYLDEDLKLLPVEVTVENPYRIKQYSRM
                     FDQDKTDKIDAQIIADYLRVDLHTLSPIKEEVYVGLQRLTRSRYQLVTQMVEAKQHFL
                     ENLTYKCNTLSKELANEDNKTSVFGATIMNLLTEDITLDEFSEMPLEAAAELLQKLGK
                     GRFKNPEQLVKSIQKAVRSSYRLGKVTKNSIDLVLGIIANEIKFLKKQIKEIEKAIIS
                     LLETIPEAQCLLSVPGLGAVYTAGLIAEIGQIERFDDQSKLAKYAGLTWSKNQSGNSQ
                     SENTPLNRSGNRYFRYYLIEATNRVRSTLPEFKEYYQKKKNEVPKHKHKRALVLTGRK
                     FVRLIDALLRNGQFYQPAKVVIEK"
BASE COUNT          598 a          318 c          305 g          511 t
ORIGIN      
        1 gcgacttcca tcgtttcagt caccccttag ggctattcct tattaaataa cttttaaacc
       61 ttggctattg aattttgttc ctggataata gacttatgga aacggtctat cggaacactg
      121 ctaatttcct ttgtagctat gactacagca gaaagcctgc atcccgactt attgattatc
      181 atgcctcaaa cccattagct gtaccgttca cttcttaaac tatttctagt aggaaatagg
      241 gtggctttta agaggtaaac aattgagtac tattaagcga gactgcggtt attcaataag
      301 attcagggat aaacttcaat agctaagtat tccaaaaaat ttatgaaagg aggaccttcc
      361 atgaaattat ttattggttt agacgttagt tctcaaaaat tagatacttg ttttttaaca
      421 gactccaaag agatcttgtt tgaaggttca cttagcaacg atttaatcgg agctagcgaa
      481 atcaaacaaa gaattctcga ctaccaagaa acctttggtt tctgccgaat tgtcataggt
      541 atggaatcga cttctgttta tagttttcac ccagcaatgt ttttctactt agatgaagat
      601 ttaaagctgt tacctgtcga agttactgta gaaaatcctt atagaatcaa acagtattca
      661 agaatgttcg atcaggataa aacagataaa attgatgcac agatcatagc tgattatcta
      721 cgagtagatc tccatacatt gtctcctatt aaagaagaag tttatgttgg acttcaacga
      781 ctaacaagat ctcgttatca attagtgaca caaatggtag aagcaaaaca acatttttta
      841 gaaaatctga cgtataaatg caacacctta tcaaaagaac ttgcgaatga agacaataaa
      901 acttccgtat ttggagctac gattatgaat ctcctaacag aagacattac cttagatgaa
      961 ttttcggaaa tgcctctgga agcggccgct gaattacttc aaaagctagg aaaaggtcga
     1021 ttcaaaaatc cagagcaact tgtcaaaagt attcaaaaag ctgtacgtag ttcttatcgt
     1081 ttaggtaaag taaccaagaa ctccattgac cttgtattag gtataatcgc taatgaaatc
     1141 aaatttctaa aaaaacagat taaagaaatt gaaaaagcca ttatttcctt acttgaaaca
     1201 attccagaag cccaatgctt attaagcgtc ccaggattag gagctgttta tactgcgggc
     1261 ttaatcgctg agattggtca aatcgagcga tttgacgatc aatccaagtt agcgaagtat
     1321 gccggtttaa cttggtctaa aaatcagtca ggaaactctc aatctgaaaa cacgccacta
     1381 aatcgttctg gaaatcgcta ttttcgttac tacttaattg aagccaccaa tcgagtaaga
     1441 agcacacttc cagaatttaa agagtactac caaaaaaaga aaaatgaagt acctaaacac
     1501 aaacataaac gagcgctcgt cttaaccgga agaaaatttg tgcgcttgat cgatgcgcta
     1561 ctacgcaacg gtcaattcta tcagccagcg aaggtggtga tagaaaaata acgtaaagtt
     1621 atttgcgaaa atcttcgtga acaacccgaa aaaaatttga ttttggtcgg gtctagttca
     1681 gcgcggtcta atttttcaaa atctaactca tattttaaaa tttatatctt ga
//
LOCUS       DAKCAA010000155         1724 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000155 DAKCAA010000000
VERSION     DAKCAA010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1724
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.159"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..1647
                     /locus_tag="OUE31_002810"
     rRNA            <1..1647
                     /locus_tag="OUE31_002810"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          474 a          362 c          519 g          369 t
ORIGIN      
        1 ctggagcgct tagaagtgag aatgccggta tgagtagcga aagacaggtg agaatcctgt
       61 ccaccgaatg actaaggttt cctggggaag gctcgtccgc ccagggttag tcgggaccta
      121 agccgaggcc gacaggcgta ggcgatggat aacaggttga tattcctgta cccgttgttt
      181 ttgtttgagc aatggaggga cgcaggaggc taaggaatgc agacgatcgg aaatgtctgt
      241 ccaagcagta agtctgaaga ggagtcaaat gcttcttttc ttaaggacaa gctgtgatgg
      301 ggagggaaat aatagtaccg aagttcctga tgtcacactg ccgagaaaag cttctagtga
      361 gaaaacagcg gcccgtaccg caaaccgaca caggtagtcg aggagagaat cctaaggtga
      421 gcgagagaac tctcgttaag gaactcggca aaatgacccc gtaacttcgg gagaaggggt
      481 gctgatcata cgatcagccg cagtgaatag gcccaagcga ctgtttatca aaaacacagg
      541 tctctgcaaa atcgtaagat gaagtatagg ggctgacgcc tgcccggtgc tggaaggtta
      601 agaggagtgc ttagcgcaag cgaaggtacg aattgaagcc ccagtaaacg gcggccgtaa
      661 ctataacggt cctaaggtag cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg
      721 cgtaacgatt tgggcactgt ctcaacgaga gactcggtga aattttagta cctgtgaaga
      781 tgcaggttac ccgcgacagg acggaaagac cccatggagc tttactgtag tttgatattg
      841 agtgtctgta ccgcatgtac aggataggta ggagccgtag aaatcggaac gctagtttcg
      901 atggaggcgc tggtgggata ctacccctgc gttatggcca ctctaacccg caccactaat
      961 cgtggtggga gacagtgtca gatgggcagt ttgactgggg cggtcgcctc ctaaaaggta
     1021 acggaggcgc ccaaaggttc cctcagaatg gttggaaatc attcgaagag tgtaaaggca
     1081 gaagggagct tgactgcgag accaacaagt cgagcaggga cgaaagtcgg gcttagtgat
     1141 ccggtggttc cgcatggaag ggccatcgct caacggataa aagctaccct ggggataaca
     1201 ggcttatctc ccccaagagt ccacatcgac ggggaggttt ggcacctcga tgtcggctcg
     1261 tcgcatcctg gggctgtagt cggtcccaag ggttgggctg ttcgcccatt aaagcggcac
     1321 gcgagctggg ttcagaacgt cgtgagacag ttcggtccct atccgtcgcg ggcgttggaa
     1381 atttgagagg agctgtcctt agtacgagag gaccgggatg gacttaccgc tggtgtacca
     1441 gttgttctgc caagggcatt gctgggtagc tatgtaggga agggataaac gctgaaagca
     1501 tctaagtgtg aagcccacct caagatgaga tttcccattt ctttaagaaa gtaagatccc
     1561 tgagagatga tcaggtagat aggtcaggag tggaagtaca gtgatgtatg gagcggactg
     1621 atactaatcg atcgaggact taaccaatag gttaaaagaa aagaactcgg aaaaaaactt
     1681 atgtgacttc aaatccagtt ttgagtgaac aaaatttact caat
//
LOCUS       DAKCAA010000156         1720 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000156 DAKCAA010000000
VERSION     DAKCAA010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.160"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            994..>1720
                     /locus_tag="OUE31_002811"
     CDS             994..>1720
                     /locus_tag="OUE31_002811"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223735.1"
                     /translation="MFTSCKEKRLKFAIRKKKGGGAASFIIGCLIFGNIFLNGAIANA
                     SSIENSYAISGFGNQTKGGYFLYNKGIKTESVIDNQVAFCFDKNVIAKLNDRGFSNPG
                     YQLYNEKDEQLLKVYSNEKINKVRNIMAYAWDNFITKYPYLNTYTAASNDDRASLARG
                     ISHAIWVTLGQTTEKKSRSDLGGVNTNAYKFYKEALNYKPLAKDINNYDISLLIPTDD
                     NNILQVNASQSLITVKKIDPDKPV"
BASE COUNT          648 a          218 c          259 g          595 t
ORIGIN      
        1 atgggaacat acacaatcta atagtatgtc agatatgtat ataaaattag aaaactgagc
       61 gaaagaaaca ttggaagaat attttttaac tatgctcttt tatatctata tataatatga
      121 aaatattatt tggagaaata gattctgatg gactgagaaa aagtataaaa agctataaaa
      181 aatataaaaa gaaaaaatat gctgatacac gttgtatcta ttttcatccc gaaattccca
      241 taaagtgaca gcatacttta ttcatttaat catggtataa gaagcagcta tttctacttt
      301 ttgagaactt aattttaagc ttgcgctata tttttcgcta caacattata aaaaataagt
      361 taatatgctt attttttgct ttgataattc taatatacat tttcaggggc aactccttcc
      421 cctgagttgc ccttagagag tgatattggg atatccctga acctattata gaaataccaa
      481 catcttagct caacaaattt gctttatatt gcaaaaaatg atctaaatta tctctttttt
      541 tatctataga ttattaaatg tatggaagaa ttaaaataag ataataaatt ttggaaaaga
      601 aatcatattt caagtcctaa gattaacaac aaagcttatt atatataaat aaaaactgtt
      661 caagaatatt ttcttataaa tagttttatc ttatttacaa atataataga actcagtgga
      721 cttattccca gatagttttt agataacact gatagtgaaa tgttgaagca aaattagcat
      781 tgattacctg tctaatttta atgttttata gtgagtctac ctgaaaataa aagtgcctca
      841 tcataattgt ttcttaaaaa ataaacgatc atttttttat tgaaatttcc ggaaaattaa
      901 tttatacttt tatcgaaaaa cattctaatt tgaatgcttt ttctttttgt ctataaaaca
      961 tgaacgttca ttttgtggta aggagagatg ggaatgttta ctagttgtaa agaaaaaaga
     1021 ttgaaatttg caattagaaa gaagaaaggt ggtggtgctg cgtcctttat aattggctgt
     1081 ttaatttttg gaaacatatt tctcaatggc gctattgcta atgcgtctag tatagaaaat
     1141 agttatgcaa taagtggttt tggtaatcag acaaaaggtg ggtatttctt atataataag
     1201 ggtattaaaa ctgaaagtgt tattgataac caagtagctt tttgttttga caaaaacgtt
     1261 atagctaaac tgaatgatcg tgggttttca aaccctggtt atcaattata caatgaaaaa
     1321 gacgaacaac tcttgaaagt atatagtaat gaaaaaatta ataaagtaag aaatatcatg
     1381 gcttacgctt gggataattt tattactaaa tatccctatt taaatactta tacagccgct
     1441 tctaatgatg atcgtgcttc tcttgccaga ggaattagtc atgctatttg ggtaaccttg
     1501 ggacaaacaa cagagaaaaa atcaagaagt gatttaggtg gcgtaaatac taatgcttat
     1561 aaattttata aagaagctct aaattacaag ccacttgcaa aagatattaa caattatgat
     1621 attagtttac ttattccaac tgacgacaat aatattttgc aggtaaatgc ttctcaatca
     1681 ttaataacgg ttaaaaaaat cgatccagat aaaccagtaa
//
LOCUS       DAKCAA010000157         1675 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000157 DAKCAA010000000
VERSION     DAKCAA010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.161"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            307..1557
                     /locus_tag="OUE31_002812"
     CDS             307..1557
                     /locus_tag="OUE31_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCU0223736.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     ETILEFNDSYHFDQIVIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFS
                     RMFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQH
                     FLENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGK
                     GRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQ
                     VIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQ
                     SQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARK
                     FTRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          551 a          327 c          301 g          496 t
ORIGIN      
        1 tcgatattgt gtgatttctc agagtacaat ggatgtatgg aaaggatcca acgggaattt
       61 gctatttcct cctgtagcgt ttgtctaccc tgtttagtct gttacccgaa ccactgttat
      121 cactaccaac tcattagctg tttcgataat ggactagact ttcaaatagt agtttggaag
      181 gcagcttcta gctcttttat caccgtattc tattaggcga ggttgtggct atacagtgag
      241 tttctgggaa atcccacagt atcgaagcat tttccaaaat ttatatcgaa aggaggtcct
      301 tcttccatga aattatttgt cggtattgac gttagctctg aaaaactaga tgtttgtttt
      361 ttaacagacg acaatcaatt gtctatctta tctgaaatct ctgttgccaa tgacatcgaa
      421 ggtgcttcat tcatacgaga aacaattctt gaattcaatg acagctacca ctttgatcaa
      481 attgtgattg gcatggagtc aacgtccatg tacagcttcc atccttccat gttttttcat
      541 gaagatgaga aactaaagaa gctcaacaca cttgtaacga ttgaaaatcc ttttcgggtg
      601 aaacaattta gtcgcatgtt tgatgagaat aaaactgatc gaaacgatgc attaagaatc
      661 gctgatttct tgcgtattca acgattcaca acttccccta tcaaagaaga gaaatacatg
      721 gccttacagc gtttaacacg tactcgctat caacttatta agcaattgat tcgtacaaag
      781 caacattttc ttgaaaatct aacgtacaaa tgtaatacgc ttgctcgaga aatgcgagac
      841 gaatcgacga gtctttttag tgcaaccctc atttcactca tgacggaaga tttcacattg
      901 gatgaacttg ctgagcttcc tttagaagct ttctgtgatt tacttcaaga aaaaggaaaa
      961 ggccgtttca agcaaccaga aaaaatcgct aaagcaattc aacgtgcaat taccatgagt
     1021 taccgcctag gtgctcttgc acaagaatca attaatgttg ttttaagtgt tctcgtacga
     1081 gaaatacgag cacttgaaaa aaatatcaaa gaattagata aagccatcga acaagtaatt
     1141 gttgtcattc cagaatatca atgcttaacc agtattccag gcgttggtaa agtctatgct
     1201 gccggtttaa tcgctgaaat tggtcaaatc gaaagatttg aagatcagac aaaattggca
     1261 aaatacgctg gattaagttg gaaagtgaac caatctggaa actatcagtc gcaaaataca
     1321 cctctgacaa aacaaggaaa tcgatatttt agatactact tagttgaagc tgccaactct
     1381 gtaaaaaatt atcttcctga atacaaagct ttttatcaaa gtaaatataa ggaggttcca
     1441 aagcatcaac acaaacgtgc actcgtccta accgcaagaa aatttacgcg tctggtggat
     1501 acgctactac gtaaacacca actctatacg ccaccaagga gtgtgataga gaaataacaa
     1561 tccgttattg acgcaaatcc ttgaatcaac ccgaaaaaaa tttgattttg atcgggtcta
     1621 gtttcgtgcg cttcaaaaca tattactcaa taaagaaaat cttaaatttc atctt
//
LOCUS       DAKCAA010000158         1629 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000158 DAKCAA010000000
VERSION     DAKCAA010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1629
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.162"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            287..694
                     /locus_tag="OUE31_002813"
     CDS             287..694
                     /locus_tag="OUE31_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223737.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            708..1109
                     /locus_tag="OUE31_002814"
     CDS             708..1109
                     /locus_tag="OUE31_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223738.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1111..1482
                     /locus_tag="OUE31_002815"
     CDS             1111..1482
                     /locus_tag="OUE31_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223739.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
BASE COUNT          612 a          209 c          283 g          525 t
ORIGIN      
        1 tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta atttgttagt
       61 aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata gaggcacttt
      121 tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc ttacaaaatt
      181 agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg actagcaaaa
      241 gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt cttatagagt
      301 acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg ttattaataa
      361 agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt tatcattttc
      421 tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag tagaaattga
      481 agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg taagcttgcc
      541 tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg ttgaagaagc
      601 aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc aaatctttga
      661 tatcaaggtc aacaaaccag tggaaaaaaa ttaaggagac gatacggatg cttgatatag
      721 taccatcaaa tacacatcgg agtggtagct taataaattt tgctgcgatt tttgcttgcg
      781 catcggtaat tctagcatct ccagttgttg tggatgcaag ttctactccg aaaactaaaa
      841 atgataatca acttgtaatt actacaaaaa atgagattaa cacaatttca agtaatgatg
      901 gcaaaatttt tgatgtgata aatacggttt taaaaagaaa agctgaaatc aatataaaat
      961 atgatgaaga tttaaacttg tatttctttg ttatcaaaac aacatctgaa ttgttttcct
     1021 cagattacga tgttttggat actctcgata atgtattatc tgactataaa tatatgggga
     1081 aatctgtagt agcaactttg ggggaataaa atgtttgact ttaatgaata tttatctatt
     1141 tccaaacaaa ttgaatcaga tgataaatat aattctaaag aatcttatag aagaactgct
     1201 gtttcaagag catactacag tgcttttaaa aaatctgatg agtatttgaa agaaaattat
     1261 gatattattt ataatggaag tagcggaaaa ggaagccacc aaaccgtttg gaatttgttt
     1321 tcaacagtta aggaattgaa taccttagga atacataata gtgggtatag aatgttagag
     1381 aaaagaaaat gtgctgacta tattcctaat gaaaccatta cgaaaacaga tatggcgctg
     1441 atgaatcgag aagcagaaaa aataataaac aaactcacct aatgaatttc aagcgagttt
     1501 gtttgttatt tttttattta atctttgtat ctttctggat caacgaaagt atactttata
     1561 tagtcataac gccgatgatc gctacgtgcg tccggcacgt cagtcacgat atcaaacaaa
     1621 aagtataca
//
LOCUS       DAKCAA010000159         1456 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000159 DAKCAA010000000
VERSION     DAKCAA010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.164"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            108..1040
                     /locus_tag="OUE31_002816"
     CDS             108..1040
                     /locus_tag="OUE31_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HCU0223740.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1112..>1456
                     /locus_tag="OUE31_002817"
     CDS             1112..>1456
                     /locus_tag="OUE31_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223741.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          227 g          420 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaatgggat gaaaaataca agccaactgt aaaagaaagt tcctatcgaa caactcaggt
     1381 ttatctatca ttaatttcaa aatatataaa agatgatgta cttgtaaaaa acgttaatag
     1441 taatcttata caagat
//
LOCUS       DAKCAA010000160         1451 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000160 DAKCAA010000000
VERSION     DAKCAA010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.165"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            105..1406
                     /locus_tag="OUE31_002818"
     CDS             105..1406
                     /locus_tag="OUE31_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCU0223742.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          476 a          293 c          264 g          418 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg
     1321 cttatggctt tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga
     1381 ttacctatga atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttcttat
     1441 ctcactctat c
//
LOCUS       DAKCAA010000161         1424 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000161 DAKCAA010000000
VERSION     DAKCAA010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.166"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(150..1337)
                     /locus_tag="OUE31_002819"
     CDS             complement(150..1337)
                     /locus_tag="OUE31_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HCU0223743.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAKCAA010000162         1423 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000162 DAKCAA010000000
VERSION     DAKCAA010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.167"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            98..1390
                     /locus_tag="OUE31_002820"
     CDS             98..1390
                     /locus_tag="OUE31_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCU0223744.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          463 a          292 c          257 g          411 t
ORIGIN      
        1 acaccagcat cttttttatt ttccaaaaca tatagaaaag acaccttgaa atcctttaga
       61 attaatttgg cgaaccaacc caaaaggagg aatcaagatg tcttacactc accttatcaa
      121 agaaacatta gatattctag acttatcagt tacttttaac gaaaattgtc tcacaaaaga
      181 aaaatacaaa gggcaaatct gtcatattta tcgtggaaac ttgatttata cagcccaaga
      241 atgcatccac tgtaaacacc agattgcttc agatattgtg cgttggggta caacaaccgt
      301 ccggttgtta atgaacgatg tttctgaata ccgtacctac ctcgaattga aaaagcaacg
      361 cttcaaatgc aaagcttgtc agcggacctt tgtcgcagat acttctgttg cgaaaaaaca
      421 ttgtttcatc agtgagaaag tccgctggtc tgtcgtgact cgtctgaaaa aaaatacctc
      481 aatgacagag atcgccgctc agaaaaatct atcggtctct tctgtttacc gtattatgaa
      541 gcgattttat cgtccgttga atccttttcg gacaccgtta cctaaggtac tttgttttga
      601 tgaattcaaa tcagttcggg gtgtttcagg tgctatgagt ttcatcatga tggatggaca
      661 aacacagcgc ttattggaca ttgtcgagaa ccgacaactg ccttttttaa aacgttattt
      721 tagtcatttt tcacgagaaa ttcgtgaagc ggtcgaatgg atcgtgattg atatgtacgc
      781 tccttatgta tcgctcgtta aaaagctgtt tccaaaagca cagctgatta ttgaccggtt
      841 tcacatcgtc caacatattg gtcgtacctt tcgcaatcat cgaatcaaag aaacgaacca
      901 actattaaaa agcaaagaac aaaaacacta tcaattaggt aagcaattaa aaagatactg
      961 gaaacttctt caaaaagatg aacgcaagct tgattatact cgacgccttt ggcgacctgg
     1021 cttcaaagct catttaacag agaccgatat tgtggatcgc ttactgaaag ggagccctgc
     1081 tttgcgtgta ggctatcagt tatatcaaga ctttctttac gctgtaaagg aacgagacta
     1141 cgtatcgttt gaagaactac ttaccaataa tatcatgctt cccgaaggct atcagacgac
     1201 cttgagaacg ttccagaaat ttctgccaca aatcaaaaat gctttacaac aaagttattc
     1261 aaatggccca cttgaatgtc tgaacaacca tatcaaagtg ttaaaacgaa atgcatatgg
     1321 ctttcgtagc ttttataatt tcaaattgcg catcatgatt cgtcatggca acgcattgat
     1381 tttcaactaa aaaagatcaa gaggaactga tccacttgat ctc
//
LOCUS       DAKCAA010000163         1390 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000163 DAKCAA010000000
VERSION     DAKCAA010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.169"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..171
                     /locus_tag="OUE31_002821"
     CDS             <1..171
                     /locus_tag="OUE31_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCU0223745.1"
                     /translation="KYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMDIPGMADEMRR
                     PMMLIVSAKKKM"
     gene            204..1112
                     /locus_tag="OUE31_002822"
     CDS             204..1112
                     /locus_tag="OUE31_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HCU0223746.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1109..1357
                     /locus_tag="OUE31_002823"
     CDS             1109..1357
                     /locus_tag="OUE31_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin acetyltransferase"
                     /protein_id="HCU0223747.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLLTRGAS"
BASE COUNT          497 a          200 c          305 g          388 t
ORIGIN      
        1 aaatatcata gaacactgac cacatatcta aatacactgc tttcaaatag ttttataata
       61 aatcagattg tggagccaca gccgccagag aacatgatgg atattccggg gatggcggat
      121 gaaatgcgac gcccaatgat gctgattgta tcggcaaaaa agaagatgta ataatataga
      181 aaaaataaac gaggagtatg taaatgagat cagaaaaaga aatgatggat ttagtacttt
      241 ctttagcaga acaggatgaa cgtattcgaa ttgtgaccct tgaggggtca cgcgcaaata
      301 ttaatatacc taaagatgaa tttcaggatt atgatattac atattttgta agtgatatag
      361 aaccgtttat atctaatgat gactggctta atcaatttgg gaatataata atgatgcaaa
      421 agccggagga tatggaatta ttcccacctg aagaaaaggg attttcctat cttatgctat
      481 ttgatgatta caataaaatt gatcttacct tattgccctt ggaagagtta gataattacc
      541 taaagggcga taaattaata aaggttctaa ttgataaaga ttgtagaatt aaaagggaca
      601 tagttccgac tgatatagat tatcatgtaa gaaagccaag cgcaagggag tatgatgatt
      661 gctgcaatga attttggaat gtaacacctt atgttattaa aggattgtgc cgtaaggaaa
      721 ttttatttgc tattgatcat tttaatcaga ttgttcgcca tgagctgctg agaatgatat
      781 catggaaggt cggcatcgaa acaggcttta aattaagtgt aggcaagaac tataagttta
      841 ttgaaaggta tatatccgag gatttgtggg agaaactttt gtccacctac cggatggatt
      901 cctatgaaaa catatgggaa gcattatttc tatgccatca attgttcagg gcggtatccg
      961 gtgaggtggc ggaaaggctt cattatgcct atccggagta tgataggaat ataacaaaat
     1021 ataccaggga catgtataaa aaatacactg gtaaaaccgg ctgcctggat agcacatatg
     1081 ccgctgatat agaagagagg cgggaacagt gattacagaa atgaaagcag ggcacctgaa
     1141 agatatcgat aaacccagcg aaccatttga ggtgataggt aagattatac cgaggtatga
     1201 aaacgagaat tggaccttta cagaattact ctatgaagcg ccatatttaa aaagctacca
     1261 agacgaagag gatgaagagg atgaggaggc agattgcctt gaatatattg acaatactga
     1321 taagataata tatcttttaa cccgtggtgc tagttaattt taatatccta aagaatatct
     1381 caaagttcct
//
LOCUS       DAKCAA010000164         1326 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000164 DAKCAA010000000
VERSION     DAKCAA010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.171"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            82..>1326
                     /locus_tag="OUE31_002824"
     CDS             82..>1326
                     /locus_tag="OUE31_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HCU0223748.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFE"
BASE COUNT          449 a          258 c          253 g          366 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgag
//
LOCUS       DAKCAA010000165         1283 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000165 DAKCAA010000000
VERSION     DAKCAA010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.173"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(88..957)
                     /locus_tag="OUE31_002825"
     CDS             complement(88..957)
                     /locus_tag="OUE31_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HCU0223749.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
BASE COUNT          371 a          253 c          203 g          456 t
ORIGIN      
        1 tattttctct ttctatctct agaataagcg atagtatgac cgttcataaa atgacgagac
       61 atgcgacaat cgttaagaaa gaaaaagtta agcgtcgcat cgaatgtcag ttttattctt
      121 ttcttttggc tcactgacga accaccattc gattcctata gcatcataga ttgtgagtac
      181 tgtgtgcttt ttgtctaaga agaaatcaac tgatagttgc tgcaagtgag caatcagtcc
      241 ttccatgctt tcagtatcga tcatgaattt cagaaaatca agtccaatca cttcatctgt
      301 aggcaaatca attgcgcctc cgctagcttc tgtcaaacca acatggaaat ctccttcatt
      361 caatacatgg atgccctctt cttcattatg taccttcaaa ccaagtacat gattaagaaa
      421 ttggcgttct tttgttaagt tagtaacatt taaatggatt ttttcaaaat aagaacctgt
      481 tgatagttta ctgaattttt cttcagattt tcttaataat gcttcttgat ccattgtttc
      541 tggaatttct ctttggtcgt tcttattctc ttcatggtaa atttccaatt cattctcttc
      601 tgggtctacg agcaaaatcc ccatacgtcc atgatcttct aaagcttctt tgattggata
      661 attcatttta cggatacgac aaaggatatc tgccatttct tctgtgctag ggataatcaa
      721 tgaaaaacgg ttcagctttt tgatcacccc catgtgatca ttcgctctag gactttcttc
      781 cagcagcaac atttcacttc cagcttcttc tgttcctaaa atggctaatt cgttttcttc
      841 tcttttcaaa tcaaagccaa caacgttctt gtaaaaatca atcattttat ctcggtcttt
      901 cacccgaatg gctacacttt ttaaataggt ggcagccccc aattgaaaat ctttcatatt
      961 tcttgctccc ctctacgtca agctttattt taacgatgga ttcttcttct ttcaagcaat
     1021 aactttgatt ttgttaaaaa aaatgtgaga aaattcgcat tttgcttgtt ttttgtaaat
     1081 taatgagtaa aaactcttat aaaaagaggt tgtgaaaaag ctgttctgca tcaagtaata
     1141 agaacagcca aacaaaaata gctcctccta tttttcgttt ggttgggctt attaccgcag
     1201 atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa aaagtcgctt agtttcgagt
     1261 agtaagaaaa attttgtgaa aat
//
LOCUS       DAKCAA010000166         1275 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000166 DAKCAA010000000
VERSION     DAKCAA010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.174"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            34..531
                     /locus_tag="OUE31_002826"
     CDS             34..531
                     /locus_tag="OUE31_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCU0223750.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
     gene            complement(568..1251)
                     /locus_tag="OUE31_002827"
     CDS             complement(568..1251)
                     /locus_tag="OUE31_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223751.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIK
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
BASE COUNT          443 a          216 c          224 g          392 t
ORIGIN      
        1 tttatagtat actatgtcaa aaggaggagt tagatgaaca atcaaatcac actagcgtat
       61 ttagattatg atgatctaga tgctttacaa gttgtaagtg ttgtcagttt ttatgaatcg
      121 tttatcgatg gcgcagatcc acttgatatg caaggatatt tacagacaca attgacaact
      181 gaaatattgg cagtagaatt ggcacagtca accagtaaat ttattggtat taaggatcat
      241 caaatactca ttggttatat gaaagtcaat gatgaaaaag atgctataga gattcaacgg
      301 ctctatctgc tcaaagatta tcaaaacaaa gggttagggc aacggttact cgatgaagcg
      361 aatcgttatg ctaaaacgaa acaaaaacgt tatttacgtt tgactgttta tgaaaaaaat
      421 catgcaggta ttcgttttta tgaacgtcat ggatttaaaa aaatcgggat caaacatttt
      481 cctttaggaa aacaagatcg tatttgtccg attttagaaa aagaaatcta aaaaaacgtc
      541 ctcacttttg atgctgagga cgttttttta gactggtaat ggaaccataa ttcgctttcc
      601 tttttgataa atcgctaatt ccgtcacacc atttgctttt aacagagcaa aaagatcatc
      661 gaaatggaaa cggaaatgtt caaggtaatg cccatctgat ccaacactaa acaaggtacc
      721 accacgtgaa agatataaat cgatgacata ttcatataac gctaaattgt catacaagta
      781 agcgctctta gcatttaatt cgaatgccaa tttatttttg attacttgat ctagaatcgg
      841 taaaaactgc gcttcatatt gtttaaattc agcaacggat agaccaaata cccgaaaacc
      901 atagtcaaaa tgagcaaaga catctgcttc tataacaact agtgcttctg aaagttgtgc
      961 aaaatactga ggaatcacaa tagcaggatc catatctttg acttcgtcat ctaaataatc
     1021 aaattgccca ttatgatgca cactgagtaa ttttaaatcg taatctttat cggctaaata
     1081 gtcgatgatc cgatcctttt cagaagcgat gtaaccgatt ttgatgcctt ttaaaacacg
     1141 attgccaaaa cgcttattta agctatcgat tgtttgactg tacatttcat aatcggggat
     1201 atcatcgact ttagtaacag gattggctaa gtcaaaatgt tcagttgtca cgacgtaacc
     1261 atcgtagttt gttaa
//
LOCUS       DAKCAA010000167         1207 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000167 DAKCAA010000000
VERSION     DAKCAA010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.175"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(127..675)
                     /gene="aac(6')"
                     /locus_tag="OUE31_002828"
     CDS             complement(127..675)
                     /gene="aac(6')"
                     /locus_tag="OUE31_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCU0223752.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          359 a          242 c          176 g          430 t
ORIGIN      
        1 gtacacggtg ttccaaaagt agcttcttcg gaaataagtt ggaatttcac aaaaattcaa
       61 gaagtaattt tcgtaaattc cttcttattt cttgaagctg attacttctg tcacaacctc
      121 tttttattat tgagaatttg gtcgaggaat aatcgttttt gccatccaaa tatccggttt
      181 gtcccagcca tttgcatttg gtaagacacc tacgatttta taacctaatt tttcatagaa
      241 ttcatacgga tgttcacgaa ggttctggat ggaagccact ttatcaaatg tatgctcata
      301 caggtccgtt tgacttaacg ttgttccatg gtctaaatca tccgtaccta aataaatcgt
      361 gattcctcct ctggaagcta cttctttttc taagtaattg actaatcgag tacctatttg
      421 gttctttcgt cgggagcttt ctacaactaa tggatgcaat tcccaacctg tgataccgta
      481 ttgagggatt gcaccaataa atcctactaa ctcatcttgg tctaccgctg ctaccgcgat
      541 tcgttctgga ttcatcattt cttctacttc ttctgccgag ctgtctccat attcttccgg
      601 ccaagtcagt ctcagtaaat cagaaagctg atctttcaat actggattat tacggtcaaa
      661 ttcactgatt atcatacgtc ttcccccttg ttcttgctta ttctaacagt ccttttgaaa
      721 aaacgaaatg ttctcgctca aaaatcttta gctaccaatc agtatctcta ttctttcatt
      781 atttatctta cttataaaat aaaaaaatta tacagaaaca ctttattcaa aataggaaag
      841 atcaggaaag ccatcaattg gaggaaaaaa ctctgtttgt tcatcatgat atagattatc
      901 ttttgcttta aaaaaaacca attatgaatt gacaaataaa acctgttttc atataataat
      961 cttaattttt agaattttta gataattaca aaaaagcaaa gggaatcggt agaaatacta
     1021 agaggaacaa aaattcatta ttgtcgtttt caatgttttt gtacttgttc gtttttagga
     1081 tacttattga tgatttcaag gtgttcatgc caccttattc atcacttatc ctgtcttagg
     1141 ttcacctcta ctccatctac agccgcagtc agatcgatca ctctttaaaa ttttaacccg
     1201 tttcaac
//
LOCUS       DAKCAA010000168         1192 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000168 DAKCAA010000000
VERSION     DAKCAA010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.176"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            143..400
                     /locus_tag="OUE31_002829"
     CDS             143..400
                     /locus_tag="OUE31_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223753.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..1063)
                     /locus_tag="OUE31_002830"
     CDS             complement(632..1063)
                     /locus_tag="OUE31_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HCU0223754.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          454 a          151 c          148 g          439 t
ORIGIN      
        1 ttttctgtcc acgttcattt tactccaaag ttttcctcat ttcaaaagaa aatcacagaa
       61 tacacgaaga agcgtttcta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt attactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaataa
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacata ccactttgta
      841 taattgtaat tattgctgaa gcaattgaaa caatcaatag taaagacctg tgttcggaag
      901 cctgatcaat taatattggg atactagctg ataagactat ttttataata tttccgatac
      961 caattactct attataaaat cgaatttctt tttttaatct atcgattgta gaatcaatag
     1021 attcgataaa cgctttttga tccatcattt tctctccaat cattttatta aaatcattaa
     1081 caaaaatatt ataataggat ttaagtaagt tctaactaat cacatataaa aataaaaaaa
     1141 catttgtatt ttatcaaagt tttattatac ttgtcaattt gtgtacatcc ta
//
LOCUS       DAKCAA010000169         1089 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000169 DAKCAA010000000
VERSION     DAKCAA010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.177"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            4..978
                     /gene="bsh"
                     /locus_tag="OUE31_002831"
     CDS             4..978
                     /gene="bsh"
                     /locus_tag="OUE31_002831"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HCU0223755.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          382 a          135 c          187 g          385 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagttact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaaactaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgatgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataagtta attagttatc caattataga aaaacaacaa
      961 attaaatata taaattagtt aatgtgttgt gattgattat ttaatataga tataatacaa
     1021 aaaggcaaag atattttcaa aacatttttt cttgatgtga tatccttgtc ttttttgtaa
     1081 tgtttttaa
//
LOCUS       DAKCAA010000170         1073 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000170 DAKCAA010000000
VERSION     DAKCAA010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.178"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..>1073
                     /locus_tag="OUE31_002832"
     rRNA            <1..>1073
                     /locus_tag="OUE31_002832"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          329 a          214 c          308 g          222 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctca ctagtcgagt gaccctgcgc cgaaaatgta
     1021 ccggggctaa acatattacc gaagctgtgg agtacacctt taggtgtatt ggt
//
LOCUS       DAKCAA010000171         1062 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000171 DAKCAA010000000
VERSION     DAKCAA010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.179"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(37..993)
                     /locus_tag="OUE31_002833"
     CDS             complement(37..993)
                     /locus_tag="OUE31_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223756.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aa
//
LOCUS       DAKCAA010000172         1014 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000172 DAKCAA010000000
VERSION     DAKCAA010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.180"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..437)
                     /locus_tag="OUE31_002834"
     CDS             complement(<1..437)
                     /locus_tag="OUE31_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HCU0223757.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDI"
     gene            complement(497..706)
                     /locus_tag="OUE31_002835"
     CDS             complement(497..706)
                     /locus_tag="OUE31_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223758.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            complement(773..1012)
                     /locus_tag="OUE31_002836"
     CDS             complement(773..1012)
                     /locus_tag="OUE31_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223759.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
BASE COUNT          276 a          222 c          134 g          382 t
ORIGIN      
        1 tgaatatcag aaaataaaac acctggcatt tccatgttat gacctgctag gacatagttt
       61 cctttgccca tttcggcatc ttcataaaaa taagtagccg ctccaagact caaagtgtat
      121 tgatttgccc ctttaaaaat tggcaatgct aaaccaagtg caggaatctg aatttgtgca
      181 aatacttgtt tattgacgcc catttcgatt gcttcttttt gtatggacaa catttgcccc
      241 aaagacatat cattattgac gttcgttgca tcctccttat aactctttgc atgtgcattg
      301 atttgatcta cgggcatctt tttttctata ttttgcttaa acacctctcc ttcatgtttt
      361 tggtagctaa catagccaaa cacactgcaa aagacgatta aagtgactcc taaaaaacca
      421 aataaccatt ttttcatcca tctgcctcct ttcagacaaa acaaaaaaac tttttctcat
      481 ttccatagaa aaagttttaa aaatgaattc tataagttcg tctcaactgt tcaaagtttt
      541 tcattgaacc taacaaacaa gctttctctt ttcctgttaa ctgcatatca ttgatatatt
      601 gcgcgacaga taatctttta aggtgttttt gcttcatcgt ttttagtaac ttttcttcca
      661 tttctttcga cacttttttt ctgttttcga tttcttcata attcatgagt tttcctacct
      721 tccttgtttt ttgcaaaaat aaaaaagcct atgatcacat acgctctaca cttcagtctt
      781 gggttatctt tttctttcgt ttaattactg gccgtgctgg tttcaaatcc ttgattccat
      841 tatgggttct ccaataatcg aattcttttc gcaatctttc tttttccata tctgttcctt
      901 tagataaggc tttgaatact tctttaggtg aataaccacg agctaacagc tgtacatacc
      961 ttccttttgt caaagtatcc atatccatcg cctctaaaac tggtcgcgcc atct
//
LOCUS       DAKCAA010000173         1006 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000173 DAKCAA010000000
VERSION     DAKCAA010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.181"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..>1006)
                     /locus_tag="OUE31_002837"
     rRNA            complement(<1..>1006)
                     /locus_tag="OUE31_002837"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          210 a          313 c          229 g          254 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtcc
//
LOCUS       DAKCAA010000174          978 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000174 DAKCAA010000000
VERSION     DAKCAA010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..978
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.182"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            21..>978
                     /locus_tag="OUE31_002838"
     CDS             21..>978
                     /locus_tag="OUE31_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCU0223760.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT          334 a          165 c          182 g          297 t
ORIGIN      
        1 attataagga gtgagtacaa atgacctata cccatcttac aacggatgaa cttgtaataa
       61 tagagtctta tttcaaaatg aatcaatctg ttgctaaaac tgcccattgc ttgaatcgtt
      121 caagacaaac gatccataaa gtatatctgt tcttcaagca aggaaaatca gccttagaat
      181 attatcaaca gtataagaaa aacaaatcaa actgtggtag acgtccgctt gttttacccg
      241 aggaacaatc agaatatatt caaagaaagg ttgttcaagg atggacaccc gatgtgattg
      301 ttggtcgtgc agcgtttcct attagttgtt ctgctcgtac catttatcgt atgttcaaaa
      361 aggggctatt tgattcttct gacttaccga tgaaaggcaa gcgtaaaccg aatggacatc
      421 aagaaagacg tggaaaacaa actttccgcc gctctattca tgaacgtgaa aaggattata
      481 gccaattctc aaatgagttt ggtcaccttg aaggtgacac tatcgtaggt ctgaaacata
      541 aaagtgctgt aattacctta gttgaacgat tatcaaaagt tatcatcaca ttgaaaccgt
      601 gtggtagaca agcgattgat attgaaaaaa aattaaatca atggtttgaa tctgtaccga
      661 aaaacctatt caaatccatc acttttgatt gtggaaagga attttcaaat tggaaacaga
      721 tcagtaatgt caatgatatt gccatttatt tcgctgatcc aggaacgccg tctcaaagag
      781 gcctaaacga gaattctaac ggattgttac gtagagatgg tttattgaaa tctatggatt
      841 tcaattcagt agatgaattt tttattcaat ctgtcgcatc taaacgaaat aatattccta
      901 gaaaatcact ggattatcga acacctttgg aagtattttt gagttacgta agtattgatg
      961 atctgtctaa cttaattt
//
LOCUS       DAKCAA010000175          976 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000175 DAKCAA010000000
VERSION     DAKCAA010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..976
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.183"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..414
                     /locus_tag="OUE31_002839"
     CDS             <1..414
                     /locus_tag="OUE31_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223761.1"
                     /translation="KVRVDDRKEVCDDFKMVYQASSKEVALEARGAFAEKWKTSYPKV
                     VESILSNDHLLTFYDFPLAIRKSIYSTNLIESFNKQIKKYSHRKEQFQNEESMERFLV
                     SSFDTYNQKFLGRSHKGFQQAEGELEQMLSQLIEN"
BASE COUNT          347 a          155 c          167 g          307 t
ORIGIN      
        1 aaagtgcgtg tcgatgatcg taaggaagtc tgtgatgatt ttaaaatggt gtatcaagcc
       61 tcatctaaag aggtggcgtt ggaagcacgt ggtgcttttg cggaaaaatg gaaaaccagc
      121 tatccaaaag tggttgaatc gattctttcg aacgatcact tgctcacttt ctatgatttc
      181 cccttggcca tacgcaagag tatttattct acgaacttga ttgaatcctt taataagcaa
      241 atcaagaaat acagccaccg caaggaacag ttccaaaacg aagagtcgat ggaacgtttc
      301 ttagtctcgt cttttgatac ttacaaccaa aaattcctag gtcgcagtca taaaggcttt
      361 caacaggccg aaggcgaact tgaacaaatg ctaagccaac tgattgagaa ttagaaacaa
      421 tctgcagtag ggaagaatca tttacacaaa attattgacg ctcccaatca aattctagaa
      481 atgctttaga ctataaaatt tattatacgg ggaaaatgca actttttagc taataaagct
      541 gaagttgcat ttttagctat ctgaaaaaaa tcgagttgaa ttttatatta atctattttt
      601 ggcacttcaa taaaaaatga accttcattt ttattgacat tttttaagta aatttgtaaa
      661 atcgttttta taaaacgtaa tagttacgtt ttataaaaac taattagaga ggagataggg
      721 acatgtctct attcaataaa acaatggttt ccttttgtag tattaagaat tttaatagct
      781 agaatattaa cataaaaact attttttgag cttaataaat agaatttaag gagaatgata
      841 ttatgaaatc aaagataatt cttggcggtt tgctactatc tacaacagct ttcgtttcac
      901 tacaatcccc acaaattacc agtgcagaaa gtttaacaaa ttcagcagaa attatagtac
      961 cgcttaattt aaaggt
//
LOCUS       DAKCAA010000176          918 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000176 DAKCAA010000000
VERSION     DAKCAA010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.184"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            22..>918
                     /locus_tag="OUE31_002840"
     CDS             22..>918
                     /locus_tag="OUE31_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223762.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKSQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIQCQKTIYYAELLQDLLEQKEALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTH"
BASE COUNT          307 a          207 c          168 g          236 t
ORIGIN      
        1 acttaaaaag gaggaaaaca aatgccttac attcttgcat tagatgtttc aatgggacac
       61 agctacagtg tcctatacaa agacgacacc tgcttatttg aagacgagat tgaacacact
      121 caaagaggat ttcatgcatt actcgaagag atccagcact tgcctgaacg tccattgatt
      181 gtttttgaag caacggggat ttattccaga ccagtcgaaa agttctttca agatcatcac
      241 ttttcttact gtttgttaaa cccgttagaa gcgaaaaaac agatggaaga aagcacctta
      301 cgcagttgga aaacagataa atcggatgcc catcggctcg cacagactca tcttaaaagt
      361 caacgtcagc caaaagaagt acaaagcaat ttttacttag agatgcgcga tttagcccgt
      421 ttttatcaag aaattgagaa gaaaatcact cgtctgcgca tggatttaca caactgtctt
      481 cagttgactt ttccagagct tgaacagttc ttttcaaaca ggctgacccc ttacgcattg
      541 acattgatcc gtctttttcc ccatccagat tttgtattgg catctactcg gacaaaaata
      601 aaaaataaac tgatcaacga aacacggaaa aaaatctccg cgaatcgtgc cgagcaaaag
      661 gcagatcaaa tcatccacta tgcacagtgt gcctatccag ctgttgaaaa agacagtatc
      721 caatgtcaaa aaacaatcta ttacgccgaa cttctccaag atttactcga acaaaaagaa
      781 gcactggcga cacaaatgat caaaaaagcc gaaggctctc cttgcttttt gttgtaccaa
      841 acgttccctg ggattggcgc actcacagcc gctttattgc tcggtgaatt aggagatatc
      901 acacgattta aaacccat
//
LOCUS       DAKCAA010000177          906 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000177 DAKCAA010000000
VERSION     DAKCAA010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.185"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            4..582
                     /locus_tag="OUE31_002841"
     CDS             4..582
                     /locus_tag="OUE31_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCU0223763.1"
                     /translation="MDNKTNNTKTEIKKNDISKASEAIKGELVFEDKVIQKIIGIALD
                     EIDGLLTVDGGFFSNIAGKLVNTDNTTSGVDVEVGKKQVAVDLSIVAEYGKDVTTIYD
                     KIKQVISNEVRKMTGLDVIEINVNVVDVKTKEQYEKDSVTLQDHLTDAASATGEFASK
                     QIEKSKEALGVASEKVNDGVQNVKEATEPRVK"
BASE COUNT          364 a          103 c          153 g          286 t
ORIGIN      
        1 ctaatggata ataaaacaaa caatacaaaa acagaaatta aaaagaatga tatatcaaaa
       61 gcttctgaag ctattaaagg agaattggtt tttgaagata aagtaattca aaaaataatc
      121 ggtattgcat tagatgaaat tgatgggctt ttgacagttg atggaggatt cttttcaaat
      181 atagccggaa aattagtaaa tacagataac acaacttctg gagtcgatgt tgaagtaggt
      241 aaaaaacaag ttgcagtaga tctttcaata gtggctgaat atggtaaaga tgtaactaca
      301 atttatgata aaattaagca agtaatctca aatgaagtta ggaaaatgac tggcttagat
      361 gtaattgaaa ttaacgtaaa cgtcgtagat gtaaaaacaa aagaacaata cgaaaaagat
      421 tcagttaccc tacaagatca tcttactgat gcagcttctg ctactggaga atttgcttca
      481 aaacaaattg agaaatcaaa agaagcttta ggagtagcaa gtgaaaaagt taatgatggt
      541 gtacaaaacg taaaagaagc aacagaacct cgtgtaaaat agtaacttcc tttctgtaat
      601 atacaacata taaaattgaa agactaaatt taaggctctt agatatttta atgtagatat
      661 agaagaaaga actgaaatat aataaaacca gttaggtata ggacttaact ggttttagtt
      721 tctttaagtg ggagatcaac atctgaataa gcattttgtg aaagatgtag aaatctttat
      781 agctgttggt tactcatttt gtatttctta tttagttctt ttgtctcttt ctagtaaatc
      841 tttacaatat tttagttctc aatttatatt atttaaaaat tttattatcg tataaaccat
      901 tataaa
//
LOCUS       DAKCAA010000178          890 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000178 DAKCAA010000000
VERSION     DAKCAA010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.186"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..888
                     /locus_tag="OUE31_002842"
     CDS             <1..888
                     /locus_tag="OUE31_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HCU0223764.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DAKCAA010000179          857 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000179 DAKCAA010000000
VERSION     DAKCAA010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.187"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            21..>857
                     /locus_tag="OUE31_002843"
     CDS             21..>857
                     /locus_tag="OUE31_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCU0223765.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDE"
BASE COUNT          293 a          149 c          166 g          249 t
ORIGIN      
        1 attataagga gtgagtacaa atgacctata cccatcttac aacggatgaa cttgtaatga
       61 tagagtctta tttcaaaata aatcaatctg ttgcgaaaac tgcgcatttc ttgaatcgtt
      121 caagacaaac gatccataaa gtatacctgt tcttcaagca aggaaaatca gccttagagt
      181 actatcaaca gtataagaaa aacaaatcaa actgtggtag acgcccgctt gttttacctg
      241 aggaacaatc agaatatatt caaagaaagg ttgttcaagg atggacaccc gatgtgattg
      301 ttggtcgtgc agcgtttcct attcgttgtt ctgctcgtac catttatcgt atgttcaaaa
      361 aggggctatt taatccttct gacttaccga tgaaaggcaa gcgtaaacca aatggacatc
      421 aagaaagacg tggaaaacaa gctttccgtc gctctattca tgaacgtgaa aaagattata
      481 gccaattctc aaatgagttt ggtcaccttg aaggtgacac tatcgtaggt ttgaaacata
      541 aaagtgctgt aattacctta gttgagcgat tatcaaaagt tatcatcaca ttgaaaccgt
      601 gtggtagaca agcgattgat attgaaaaca aattaaatca ttggtttgaa tctgtaccga
      661 aaaatctatt caaatccatc acttttgatt gtggaaagga attttcaaat tggaaacaga
      721 tcagtaatgc caatgatatt gccatttatt tcgctgatcc aggaacgccg tctcaaagag
      781 gcctaaacga gaattctaac ggattgttac gtagagatgg tttattgaaa tctatggatt
      841 tcaattcagt agatgaa
//
LOCUS       DAKCAA010000180          815 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000180 DAKCAA010000000
VERSION     DAKCAA010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.188"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            49..815
                     /locus_tag="OUE31_002844"
                     /pseudo
     CDS             49..815
                     /locus_tag="OUE31_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          321 a          134 c          156 g          204 t
ORIGIN      
        1 aaaattaagg tgtgtagact agaagaaaac ataccaggag gaatttttat gtctaagaga
       61 acacgaagaa ctttttcaca agaattcaag caacaaatcg tcaatcttta cttagatgga
      121 aagccacgtg tagaaatcat tcgagaatat gaactaacgg cttcagcatt tgacaaatgg
      181 gtaaagcaat ctaaaacgag tggttcattc aaagaaaaag ataatcttac gcctgaacaa
      241 aaagaattgt tagaactacg taaaagaaac cagcaattag aaatggaaaa tgatatttta
      301 aagcaagcag cgctgatatt cggacgaaga gacaagtaat cgatgcgaat aagcatcttt
      361 accctatatc agcgatgtgc agaatattag gtctatcacg tcagtcctat tattattaat
      421 caaaaccaaa gaaagacgaa tcagaacttg aagaagtagt cgctgaagaa tttatccgca
      481 gccgaaaggc ctacggctca agaaaaataa aaaaagcctt atcaaaacga ggcattcaga
      541 tcagccgacg aaaaattagt agaatcatga aaaatagagg attaaaatcg agctatactg
      601 ttgcttattt taaagtacat cattctactt gcaatgaagc caaaacgaca aacgtattga
      661 atcgtaaatt cttaagagac aacccattag aagcgatcgt aacagacttg acttatgtac
      721 gagtcgggaa aaaatggaat tatgtctgtt tcattttgga tctgttcaat cgagaaattc
      781 tcggctattc ttgtggagaa cataaagatg ccgtt
//
LOCUS       DAKCAA010000181          791 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000181 DAKCAA010000000
VERSION     DAKCAA010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.189"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..782
                     /locus_tag="OUE31_002845"
     CDS             <1..782
                     /locus_tag="OUE31_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCU0223766.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          242 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc t
//
LOCUS       DAKCAA010000182          789 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000182 DAKCAA010000000
VERSION     DAKCAA010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.190"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            22..714
                     /locus_tag="OUE31_002846"
     CDS             22..714
                     /locus_tag="OUE31_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HCU0223767.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          282 a          151 c          158 g          198 t
ORIGIN      
        1 aaaaaaagga ttttagtaac aattggtcta gcttttttgt tagctggttg taccaacggg
       61 aatgaatcga aaaaagaatc aacaaaagaa acagcgaaag caacagttgc aactactaca
      121 acaactagca cagagagcaa gtcaactgca gcaagtacag aaacagcaga tacctctact
      181 tcgtcagagt cttccaaaac gactgaaaca actcaaacat ctacttcaag ttcttctgta
      241 gaggcttcat cttcctcttc agaaagcagc gaacaagttg aacaaacact gtggaatgca
      301 gacaaatccg cacaattaga ggcatttatg accaaatggg gccaaacaat gggacaacaa
      361 tacaaaagtt atacgaatca aatgagtgtg gacttatatg gtcttaaagt ccctcaagct
      421 attttgaacg gggagtggaa gatggctatt ggtggagtgc ctgtttctgc agaatggtca
      481 gaaagtggga caggtcaagc agactatcaa atcacagccg tctattccga tgcagagaca
      541 gaaccatatc tgaaaaagca cgtctatcta ttcgggtttc agcaaaatca gccaaaagta
      601 ttggtgacac aacaaaatca ggggaatccc gataattatc tttacttcaa cgagacagcg
      661 aataatgaat tgaaaaatgg ctttaatcaa atcgtttatg gacaagcaaa ttaatgagat
      721 aaacaagggg ttgtgacatg tcttttatca caaccccttg ctcagtttat ttgttagtct
      781 tttattttt
//
LOCUS       DAKCAA010000183          773 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000183 DAKCAA010000000
VERSION     DAKCAA010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.191"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..660
                     /locus_tag="OUE31_002847"
     CDS             <1..660
                     /locus_tag="OUE31_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223768.1"
                     /translation="YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNK
                     LSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKV
                     DKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          285 a          119 c          143 g          226 t
ORIGIN      
        1 tatatttctt tgttgtgtaa agaagaaatt atcgaattac ctaaaactaa ttccacaatt
       61 ggtattgact taggtattat ggactttgcg attctttctg atggacaaaa aattgataat
      121 aataaattca cgtccaaaat ggaaaagaaa ctaaagcgtg aacaacgcaa attgtctagg
      181 cgtgctttat tggctaaaaa taaaggtacc aatctatttg aagctaaaaa ttatcaaaaa
      241 caaaaacgca aagtagctag attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat gatcaaaaat cacgatatta tctgtattga agacttaaac
      361 acaaaaggta tgttgcgaaa tcataaatta gctaaaagta tttctgatgt ttcttggtca
      421 aagtttgtga ctaaattaca atacaaggct gactggtatg gacgaaaaat catcaaagta
      481 gataaatggt ttccgtctag tcagatttgt tcagagtgcg gacataaaga tggcaagaaa
      541 tctcttgaaa ttcgagaatg gacttgtcct gtttgtcata ctcatcatga tcgtgatatc
      601 aatgctagta tcaatattct gaccgaaggt ctaagactac attctatggg attggcttag
      661 atccaatcat caagaaccgt aggaactacg gggatagctt ggtaaataag agacaccgct
      721 gttagtaaag aaatacgcta tcaagtatgc tctattccca agaagctccc act
//
LOCUS       DAKCAA010000184          743 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000184 DAKCAA010000000
VERSION     DAKCAA010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.192"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..>743
                     /locus_tag="OUE31_002848"
     CDS             <1..>743
                     /locus_tag="OUE31_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HCU0223769.1"
                     /translation="RRNTDQLKQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNG
                     DFPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLL
                     NQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPN
                     ILGDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEK
                     LGCQNFNSRSVKGLESRFESILLAYSVLL"
BASE COUNT          254 a          136 c          133 g          220 t
ORIGIN      
        1 accgaagaaa tactgatcaa ctgaagcaac gcgatacagt gattattgct tgtgttatat
       61 ggggcataat taatggctat actagccaaa gagccacgta tagagcggtt tgttccgtct
      121 tatttcctaa tggtgacttt cctagtagga gtcgattcac tcgcttaagt tcaaacttag
      181 cttacactat caagattatt cgatactttt tcatcaagaa gctcaccaaa ggtgaactag
      241 tcggaattat agatagtttt cctagtccat tatgtaaacc agttagaaat agacaagcaa
      301 aactattgaa tcaaatagcc aaagttggct ataactcaac aaaaaaatct tatttttatg
      361 gtcttaaaat tcatatgatc gttactaaga ctggctttcc gattacttac tcaatcacga
      421 atccaggtgt ccatgacgtg aaagtgttag agactttatc ggaagaagcg aatcttccca
      481 atatcctagg ggacaaagga tatattagcc ataaaatcca tgaaaagctt gcccttaagg
      541 gcattactat atccgttccg ccacgtaaaa acatggataa atcagaaaaa ctagaccaca
      601 gcttacttgg aaaacaaaga aaaacagttg agactgtttt ttcttcctta gaaaaattag
      661 gttgtcaaaa tttcaactca cgttctgtta aagggctaga gagtagattt gaaagcatat
      721 tactggctta cagtgttcta tta
//
LOCUS       DAKCAA010000185          741 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000185 DAKCAA010000000
VERSION     DAKCAA010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.193"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..383
                     /locus_tag="OUE31_002849"
     CDS             <1..383
                     /locus_tag="OUE31_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223770.1"
                     /translation="IKSQRVYEKKSAGKDVPCLSTLKNRLGDIRFLFKKEVNKGLTNF
                     EILLELKNEIIRLNMEDDLSMTKFQNYSKSKHLPSVYTIMRRTNKTWEELMSEIGYDY
                     KEIKIKKQRNNLRCRSKKICSRYE"
BASE COUNT          304 a           76 c          112 g          249 t
ORIGIN      
        1 aaataaaatc acaacgcgtt tatgaaaaaa agtctgctgg taaagatgtt ccgtgtttaa
       61 gcactttaaa gaatagattg ggcgacattc gttttctttt taaaaaggaa gtgaataagg
      121 gattaactaa ttttgagata cttttagagc ttaagaatga aataattaga cttaatatgg
      181 aagatgattt atctatgaca aaatttcaaa actattcaaa atccaaacat cttccatctg
      241 tatatacaat tatgagacgg acaaataaga catgggaaga attgatgagc gaaattgggt
      301 atgattataa agaaataaaa ataaaaaaac agagaaataa tttgcgttgt agatcaaaaa
      361 aaatatgttc aagatatgaa taaacaaagt atttttcagc atatttttat ctgtaccatt
      421 attttaaata tccatagcag tttattcatg atttatgagg tttaaaatac aatactgaat
      481 tcactgctta ttttcatgtt actgcttaaa ctttgtattt taatagaaaa tagagatgtg
      541 aacgaaaaat atttatttct attacaaaag gtaaaaaatt tgatttaaaa gctaaatgta
      601 cagatgagtt ttgaattttt ctccttcaaa ttcaaaatga gagtagtagg tatgatagaa
      661 atatatcaaa tattaagata gatacaatat gcataatagg ctatgcttct ttagattttt
      721 tgattaagaa cacaataaat a
//
LOCUS       DAKCAA010000186          729 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000186 DAKCAA010000000
VERSION     DAKCAA010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.194"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            94..>729
                     /locus_tag="OUE31_002850"
     CDS             94..>729
                     /locus_tag="OUE31_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HCU0223771.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFS"
BASE COUNT          222 a          142 c          136 g          229 t
ORIGIN      
        1 tcaccaacat cttttttgta taaaaaaata tagaaaagac accctgaaat cctttagaat
       61 taatttggct accaattcat aggaggattc aagatgtctc atactcagct tatcaaagat
      121 accctaaata ttctagacct aaatatctat ttcgaggaaa attgtttaac taaagaaaaa
      181 tacaaagggc aaatttgctt gatttacaaa ggaactcttc tgtacaagcc agaagagtgt
      241 tcccattgtc tttgtgtcgt cccctctagg atcattcgtt gggggacgac aaccgttcgg
      301 ttgttactga atgatgtgtc tgagtatcgc acttatctgg agctgaagaa acaacgattt
      361 aaatgtaagt cttgccaaag aacattcgta gcggatacct ctgttgctga aaaacactgt
      421 ttcattagtc aaaaagttcg ttggtctgtc attgctcgct taaaagagaa tacttccatg
      481 acggaaatcg ctcgtcagaa aaatatttcc acttcttcgg tctatcgtgt catgaagcga
      541 ttctaccgcc cattgaatcc tttcaaacag actttgccaa aggtcttatg ctttgatgaa
      601 ttcaaatcgg ttcgaagtgt tgccagtgca atgagtttta tcatgatgga cggacaaagc
      661 catgcattat tggatattgt cgaaaatcga cgcttgcctt atttagaacg ctatttttct
      721 cggttttca
//
LOCUS       DAKCAA010000187          698 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000187 DAKCAA010000000
VERSION     DAKCAA010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.195"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..627
                     /locus_tag="OUE31_002851"
     CDS             <1..627
                     /locus_tag="OUE31_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HCU0223772.1"
                     /translation="LVMDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQI
                     MNRFRTSHSENQKKYRRLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLS
                     YNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISN
                     AFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT          221 a          156 c          127 g          194 t
ORIGIN      
        1 ctagtgatgg acatgaatgc cagctattgt cagttgctta aaacagtctt tccaaatgcg
       61 gagatcgtaa ctgaccgctt tcatattgtc caacacatca atcgcagctt caatcaatta
      121 cgtgtccaga tcatgaatcg ttttcgaacc tcacactctg aaaatcagaa gaagtaccgt
      181 cggctcaagc gatattggaa actcttactc aaagattcca cgacatggga gccactcaaa
      241 cggcattatc atcgactgtt taaacgacca attagtcaaa cagaaatcgt tgatgagctg
      301 ttaagctaca acgaagaatt gcgaactgcg tatcattttt gtcaattatt acgctattat
      361 ttcgttaaac gaggtacgga aggctttcaa gaaaccctta aaacaatttc atctacgtta
      421 cctcagtcgt ttaaaaagaa attcacgatc ttccatcgct accaatcggg tatttcaaat
      481 gcctttaagg tgtcccactc aaacggcgtc actgaggggc tgaataacaa gatcaagctg
      541 attaaacgaa ttgcgtttgg ttatcgcaac ttttataact ttcgggcacg gatctattta
      601 caacaaggtc tgatctttga aaactaaaaa aatatgcggc gcacagaacg cgccgcatat
      661 cggactaagt tttattcaaa tttgtcttca ccaacacg
//
LOCUS       DAKCAA010000188          696 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000188 DAKCAA010000000
VERSION     DAKCAA010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.196"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(53..628)
                     /locus_tag="OUE31_002852"
     CDS             complement(53..628)
                     /locus_tag="OUE31_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCU0223773.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DAKCAA010000189          655 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000189 DAKCAA010000000
VERSION     DAKCAA010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.197"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..617
                     /locus_tag="OUE31_002853"
     CDS             <1..617
                     /locus_tag="OUE31_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223774.1"
                     /translation="APYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLK
                     GNSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNL
                     RQGYQLYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYS
                     YSNGPLECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          218 a          135 c          121 g          181 t
ORIGIN      
        1 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
       61 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      121 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      181 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
      241 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
      301 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
      361 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
      421 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
      481 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta aaacgcaatg
      541 cgtacggctt tcgcaacttt tacaatttca aactacgaat tatgattcgt catggcaaaa
      601 catttttaac caaataaaca gaacagaaag aggttttctt ctttctgttc tgtcc
//
LOCUS       DAKCAA010000190          639 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000190 DAKCAA010000000
VERSION     DAKCAA010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.198"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..282
                     /locus_tag="OUE31_002854"
     CDS             <1..282
                     /locus_tag="OUE31_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCU0223775.1"
                     /translation="LIQDDLHHTHRLWLMNKINLYFGHSYVFAFYDYRTNITEVDLVI
                     SNYYIDTGKTPLLLMKNIPTERNWRLFEKTIYQLKKEKEVVKSAFCPEY"
BASE COUNT          218 a           89 c          119 g          213 t
ORIGIN      
        1 ttaatacaag atgatttaca ccatacgcat cggttatggt taatgaataa aattaatctg
       61 tattttgggc attcttatgt ttttgctttt tatgattaca ggacaaatat aactgaagta
      121 gatttggtta tttctaatta ctacatcgac actggaaaaa cgccattact gttaatgaaa
      181 aatataccta ccgaaagaaa ctggcgtttg ttcgagaaaa cgatttatca attgaaaaaa
      241 gaaaaagagg ttgtgaaatc agcgttttgt cctgagtatt agagaaacaa acggaaaaat
      301 agtttttcat attttgccgt ttttgagcta ataccgaggg acagctgatt gaacaccatt
      361 tattgagaga ttgtgaaaaa actgtcctgc atcaagtaat aagaacagcc aagtaaaaac
      421 agcttctcat gtttgttgaa tattgtgact tgtgaccgag gagttggcaa gagaacaccg
      481 tttattcgga aaaagggact gtgacactac atgtcacagt ccctttttga ttgaattatc
      541 tcatttgttt tctaattttt tctttatttg agaaaatagt tgaactggat aaaaagtact
      601 ggacgtgtca aaattatttt ggatcaaatt agatctatt
//
LOCUS       DAKCAA010000191          615 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000191 DAKCAA010000000
VERSION     DAKCAA010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.199"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            26..412
                     /locus_tag="OUE31_002855"
     CDS             26..412
                     /locus_tag="OUE31_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCU0223776.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT          227 a          102 c          122 g          164 t
ORIGIN      
        1 ataaaaataa aaaaggagat ctttcatgaa aaaaatttta gggttgatcg ttatcatatt
       61 gattgctttt ataggatgga aaggttggga ctactatcag tctacttatg taggtaaaga
      121 ttattatgcg gtagtcaaag ctccaatgcc tgcagaaact gatatcaaag cagataatgg
      181 ggaagtaatt ggaagaggtt ttaaatacaa cgtagatgct tatgctgaaa acggtgaaaa
      241 aagacagtta gatttcgatg tcattacttc tggtgactct gccaatggtt ctgcttaccc
      301 cgaaggaacg atcttgcagt tgaaagcaag cgaaaagcgg atcatagaga aaaaagtaat
      361 taccagcgat aaggtaccct catctgtaaa agaaaaatta ggcctatctt aagctaagaa
      421 tatatcgcaa aaaagcactc gaagtgagtg cttttttgct tactgattct agaaaacaaa
      481 aaaacagaat taaccttcga agtcagcctc actgttctta aagtcctaaa acaaactaaa
      541 gagcaaggca atcaatcgat ttctatacaa acaagggact gtgacaaacg tcttgtcaca
      601 gccccttatt ctgaa
//
LOCUS       DAKCAA010000192          588 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000192 DAKCAA010000000
VERSION     DAKCAA010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.200"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(65..150)
                     /locus_tag="OUE31_002856"
     tRNA            complement(65..150)
                     /locus_tag="OUE31_002856"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Leu,seq:taa)
     gene            complement(167..238)
                     /locus_tag="OUE31_002857"
     tRNA            complement(167..238)
                     /locus_tag="OUE31_002857"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(204..206),aa:Gly,seq:gcc)
     gene            complement(250..322)
                     /locus_tag="OUE31_002858"
     tRNA            complement(250..322)
                     /locus_tag="OUE31_002858"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Thr,seq:tgt)
     gene            complement(340..421)
                     /locus_tag="OUE31_002859"
     tRNA            complement(340..421)
                     /locus_tag="OUE31_002859"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(385..387),aa:Leu,seq:tag)
     gene            complement(429..501)
                     /locus_tag="OUE31_002860"
     tRNA            complement(429..501)
                     /locus_tag="OUE31_002860"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(466..468),aa:Lys,seq:ttt)
     gene            complement(505..577)
                     /locus_tag="OUE31_002861"
     tRNA            complement(505..577)
                     /locus_tag="OUE31_002861"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(542..544),aa:Val,seq:tac)
BASE COUNT          149 a          169 c          138 g          132 t
ORIGIN      
        1 cccctaacct tttgatccgt agtcaaacac tctatccagt tgagctatgg gcgcatattt
       61 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
      121 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      181 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      241 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      301 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      361 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      421 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      481 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      541 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAKCAA010000193          575 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000193 DAKCAA010000000
VERSION     DAKCAA010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.201"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            79..>575
                     /locus_tag="OUE31_002862"
     CDS             79..>575
                     /locus_tag="OUE31_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HCU0223777.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          216 a          106 c           93 g          160 t
ORIGIN      
        1 aaaatccata caaaaaagga agtcccttct gtagaataaa gttaacgaca accaattcac
       61 agaaaagagg acttccctat gaatgatttt actacagaaa ttgtgcaaac tctagtcact
      121 aaaggcgatt taaatgaatt attccgttcg cacttagaaa aagcgataaa cacactccta
      181 cggactgaat taacggcttt tttagattac gaaaaatatg atcgcactgg ttttaattca
      241 ggtaattcga gaaacggttc ttactttcga tcaatcaaaa ccgaatatgg tgaattaaca
      301 ttggaaatac ctagagatcg taatggtgag tttaaacaac aaactttacc agcctacaaa
      361 agaacaaacg atacattgga aaccactatt atccatttat tcgaaaaagg tgttacgatg
      421 tctgaaattg ctgatttgat cgaaaaaatg tacggtcatc actatactcc acaaaccatg
      481 tccaacatga ctaaagttct gactgaagaa gtaaatgcct ttaaatccag agccttaaat
      541 gataagtatg tcgctatttt tatggacgct actta
//
LOCUS       DAKCAA010000194          513 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000194 DAKCAA010000000
VERSION     DAKCAA010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.202"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(107..>513)
                     /locus_tag="OUE31_002863"
     CDS             complement(107..>513)
                     /locus_tag="OUE31_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HCU0223778.1"
                     /translation="TPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMNA
                     ASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYEDS
                     QITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          162 a          102 c           78 g          171 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttc
//
LOCUS       DAKCAA010000195          510 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000195 DAKCAA010000000
VERSION     DAKCAA010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.203"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
BASE COUNT          228 a           70 c           82 g          130 t
ORIGIN      
        1 gaattcctta ggcagctttt gctgtgtaga aaggaataaa taataacgaa agttcaaaag
       61 ctaatgccga ctattctaga cattaaagaa gacgaaaacg aacgataaag aaagaaaagt
      121 tatgaataat cgtttattga aaaaaacttg aaaaaataca aaaaattcgt tgaccaagct
      181 aaatttagtt ggtatattat tacttgtcca aaagacagaa gaaaatattt attcaaaaac
      241 ataacaaaaa agttattgac atgttactaa cgacatgata agataactga gtcgttaaaa
      301 aagaaccact tgcgaagctt gattctatcg aaaaaaactt caaaaaagtt cttgacaaat
      361 aacaaacgat aagttatgat aaatgagttg ccgaaagatt tcgaaaaacg aaatcgaaaa
      421 aaacttttaa aaaagagttg acaatcgctt gtctctctga tatgatataa aagttgctac
      481 ggcagccaaa aatgaatcgg gaaacactct
//
LOCUS       DAKCAA010000196          508 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000196 DAKCAA010000000
VERSION     DAKCAA010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.204"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
BASE COUNT          156 a           77 c           78 g          197 t
ORIGIN      
        1 cttgaggagt aaaaatgaaa aagtatatag ggttgttggt tggtatgtat atagaataga
       61 agataaatgt gaagaaattg tgcattattt cttcacattt attaggttat agtttaagaa
      121 agtttaaaca ttgcgcaatt taattatttt agctgtttct tttcataaaa aaacatgttg
      181 tgactctgag acaaatcata gtccatagtg atgtctctag agtaactacg cctaatatta
      241 cgaggcatca tattaatcta tcagcactag tacctaaact agcatccctt tcgaatattt
      301 tttcttatat aataaagttt gctttcactc ctctaatctc accaaatcga ctggcttgcg
      361 ttgtgtgata ctaggaactg attggtttag aacgactttt ctattgtaat catatttttc
      421 gccatcctcg ttgtcttcta atccttcaat gaatgatccc taatgtgtgt attaaataat
      481 ttaatttttt tgttcctatt tatttaac
//
LOCUS       DAKCAA010000197          488 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000197 DAKCAA010000000
VERSION     DAKCAA010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.205"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(78..>488)
                     /locus_tag="OUE31_002864"
     CDS             complement(78..>488)
                     /locus_tag="OUE31_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCU0223779.1"
                     /translation="GLYYSPVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAP
                     QEYLSRAYNDAPKYCANIVNTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLA
                     ELKGYQVTTGEPVCQTRRLNSRIDKVRYMFNKIT"
BASE COUNT          167 a           88 c           73 g          160 t
ORIGIN      
        1 tttaattcaa atctatatta aagaatattt catcttattt aataagaaac catatttata
       61 taacaacata aaacgcacta agttatttta ttgaacatat atcttacttt atctatccga
      121 ctatttagac gacgggtctg gcaaacaggt tcgccagtgg taacctgata tccttttagc
      181 tctgctaaac aaacactaag cccatttgta aaaaaagtta aatcattgcg ataatcttga
      241 atacatcgag caggaatttc tccaataata atgacctcat tatttttcag ttgagtattt
      301 acgatatttg cacaatattt gggagcatcg ttatatgccc gtgaaagata ttcctgtggt
      361 gcataaactt taaaactaag atatggctct aacaattctg ttccagcttt tctaaaggct
      421 tgctccagta caataggagt aagcatccga aaatctgctg gagtactaac agggctatag
      481 tataaacc
//
LOCUS       DAKCAA010000198          476 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000198 DAKCAA010000000
VERSION     DAKCAA010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.206"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            22..>476
                     /locus_tag="OUE31_002865"
     CDS             22..>476
                     /locus_tag="OUE31_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCU0223780.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFS
                     CSVSTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKK"
BASE COUNT          178 a           87 c           95 g          116 t
ORIGIN      
        1 atacaaggag agtgaacata aatgacttat acccatctta caccaaacga gcttgtaatg
       61 atagaagcat attttcatca agaaactccg gttgctatcg ttgcgaagca gcttaaacgt
      121 ggacgccaaa caatttacaa tgtctataac tttctcaaat gtggtggaac agcacttgaa
      181 tactttgaac aatacaaaga aaataagcga cgttgtggga gaaccgaaat catttttcct
      241 gctgaggaaa aagaatacat tgaaaaaaga tcaactgaag gttggacccc agacgtcatt
      301 attggccgtg cagagcgaac cttctcttgt tcagtaagta ccctctatcg ccggtttaag
      361 acgggagaat tcaatgtttt acatttaccg atgcaaggaa aacgaaaacc aaatggttat
      421 aaggaaaaac gtggaaaaca ggcattcaaa agaaatattt ctgaacgtaa aaaaga
//
LOCUS       DAKCAA010000199          473 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000199 DAKCAA010000000
VERSION     DAKCAA010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.207"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..>473
                     /locus_tag="OUE31_002866"
     CDS             <1..>473
                     /locus_tag="OUE31_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCU0223781.1"
                     /translation="YLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDIW
                     LRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVKY
                     LNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVST"
BASE COUNT          161 a           92 c           95 g          125 t
ORIGIN      
        1 attatctttg gaagaagaaa aatagacaat ccttctattc atggaaaatg gacgaaacct
       61 atatcaaaat taagggacgt tggcattatc tttatcgtgc aattgatgcg gacggcttaa
      121 ccttagatat ctggttacga aagaaacggg atacgcaagc agcctatgct ttcttaaaac
      181 gactccataa acagtttggt gagccgaaag caattgtgac cgataaagca ccttctcttg
      241 gctccgcctt tagaaagtta cagagtgtgg gtttatatac taagacagag caccgaactg
      301 tgaagtatct taacaattta atagaacaag accatcgacc tattaaacga cgaaataaat
      361 tttatcaaag tctccgtaca gcctcttcca cgattaaggg catggagacc attcgaggaa
      421 tatataaaaa gaaccgaaga aatggaacgc tcttcggctt ttcggtgtct act
//
LOCUS       DAKCAA010000200          440 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000200 DAKCAA010000000
VERSION     DAKCAA010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.208"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            11..>440
                     /locus_tag="OUE31_002867"
     CDS             11..>440
                     /locus_tag="OUE31_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCU0223782.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          168 a           57 c           88 g          127 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag
//
LOCUS       DAKCAA010000201          433 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000201 DAKCAA010000000
VERSION     DAKCAA010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.209"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(128..>433)
                     /locus_tag="OUE31_002868"
     CDS             complement(128..>433)
                     /locus_tag="OUE31_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223783.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          121 a           99 c           85 g          128 t
ORIGIN      
        1 gaatggcaac actttttttg acaaaaatta taaggtgttg tgaatgctgc ggtgttatgg
       61 ctacgattgc ccttgacaat gagcatcctc ggatctgatt ttctccggca gaagcacaat
      121 cattcaatta cgctgcctct ccagaggtat cagatccgcg ctcattatca aggattcgct
      181 tcgccaatct ctgttgtcga atttggatcg gtgtttcata cgccaacgtg ccatgtaagc
      241 gtagatagtt ccaccaatgc acataatcaa acaattctag acgtagctgt gccagtgtct
      301 caaattggta ttgatgcacg aattctactt tgacagattt ataggttgat tccacaacgg
      361 cattatcata cggacaaccc ttcctactca atgaacgagt aattccaaaa ccattcagaa
      421 tctcatgaat ggt
//
LOCUS       DAKCAA010000202          429 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000202 DAKCAA010000000
VERSION     DAKCAA010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.210"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..>429
                     /locus_tag="OUE31_002869"
     CDS             <1..>429
                     /locus_tag="OUE31_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223784.1"
                     /translation="KIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNL
                     YLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKL
                     KERKISKADPESGYYVKGEREKQFAYSAHTSCDDNGFILST"
BASE COUNT          157 a           75 c           88 g          109 t
ORIGIN      
        1 aaaatccccc atttctcaac ttttggaaag aattatgttc gccgatttag agaaacgacg
       61 gtgtttgagg atatttttgc ctatatttta gaacaagcag ttaaagcagg ttttgtaaca
      121 gaggataatt tgtatctgga ttctacccac atcaaagcta acgccaataa acataagttt
      181 acgaaagaaa tgacccatga tgaagcgaaa gcctatcagg atgaattaga agatgagatc
      241 aatcgtcaac gaatagaggc tggaaaacgc ccttttactt tggacttaga aaaggaagtg
      301 aagctgaaag aaagaaaaat aagtaaagct gatccggaaa gcggctacta cgtcaaaggc
      361 gaacgagaaa aacaatttgc ttattctgcc catacttcat gcgacgacaa tggatttatt
      421 cttagcaca
//
LOCUS       DAKCAA010000203          415 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000203 DAKCAA010000000
VERSION     DAKCAA010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.211"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..339)
                     /locus_tag="OUE31_002870"
     CDS             complement(<1..339)
                     /locus_tag="OUE31_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223785.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DAKCAA010000204          398 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000204 DAKCAA010000000
VERSION     DAKCAA010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.212"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            106..381
                     /locus_tag="OUE31_002871"
     CDS             106..381
                     /locus_tag="OUE31_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223786.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
BASE COUNT          171 a           60 c           54 g          113 t
ORIGIN      
        1 aaataaccac tatttgattt atatatattt cagtatcctt cttgttttca tataaccaaa
       61 ggcgctatga tttccatatg aaaaaaataa agtcaggtga aaaaaatgaa acttgaggat
      121 aaaaaagtca ttttgaagaa aatcaaacga ctaccagacc aaatagatgg ctatacgatc
      181 tgttctttca aaaaagacag gagtataaaa gcttatacgc aaaacacaga aaaaggaata
      241 atctatttcc tacatgaaga aggttacgat acccaaacct ttatgtttac tgaaaaaaaa
      301 gaatttcata aacagatgaa aaaactgatt gaaaaagaat ttccaagaag tcataaactc
      361 tatgtgaatc agcaatttta acttctaact gttcttta
//
LOCUS       DAKCAA010000205          359 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000205 DAKCAA010000000
VERSION     DAKCAA010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.213"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..>359
                     /locus_tag="OUE31_002872"
     CDS             <1..>359
                     /locus_tag="OUE31_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCU0223787.1"
                     /translation="GRKALDIETALNQWFSRFPKNFFKSITFDCGKEFSNWKAISNQH
                     DIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRKVNQTFISSVSNQRNHIPRKS
                     LNYRTPIEIFLSYVQEA"
BASE COUNT          122 a           69 c           60 g          108 t
ORIGIN      
        1 ggccgtaagg cattagatat tgaaactgcc cttaatcaat ggttttctcg cttccctaaa
       61 aacttcttta aatctattac gtttgactgt ggaaaagaat tttctaactg gaaagccatt
      121 agtaaccaac atgatattga tatatatttt gcggaccctg gaacaccttc tcaacgccca
      181 ttaaacgaga attctaacgg gattctgcgt cgtaatggac tgccgaaatc aatggatttt
      241 agaaaagtga atcagacatt tatttccagt gtcagcaatc aacgtaatca tattccaaga
      301 aaatcattga attacagaac accaatcgaa atatttttga gctatgtaca agaagcatt
//
LOCUS       DAKCAA010000206          351 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000206 DAKCAA010000000
VERSION     DAKCAA010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.214"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            76..>351
                     /locus_tag="OUE31_002873"
     CDS             76..>351
                     /locus_tag="OUE31_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCU0223788.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDV"
BASE COUNT          141 a           59 c           63 g           88 t
ORIGIN      
        1 agaaaaataa aaaggcattt atggtacact caaattgtat ttccgacgaa agaaaacaaa
       61 ggagtgtaac cataaatgac ctacaaacat cttaccatag acgaactgac aatgatagaa
      121 tcatattatc ttcaacataa taagccggtt gaaatcgcta accgaatggg acgtgctata
      181 caaactattt ataatgtagt caataagttc aagcaaggca agactgctct tgattattgg
      241 caccagtata aagaaaataa gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat
      301 gaagtagatt acattaaaga gaaagtcact cttggttgga cgcctgacgt c
//
LOCUS       DAKCAA010000207          346 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000207 DAKCAA010000000
VERSION     DAKCAA010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.215"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..316
                     /locus_tag="OUE31_002874"
     CDS             <1..316
                     /locus_tag="OUE31_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HCU0223789.1"
                     /translation="QFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLI
                     EQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGI
                     PA"
BASE COUNT          119 a           68 c           67 g           92 t
ORIGIN      
        1 gcagtttgat gaaccgaagg ttgtagtcac agataaagcc ccctctatta caagtgcctt
       61 taagaaacta aaagaatacg gcttttatca agggacagaa catcgtacca ttaaatacct
      121 gaataatttg attgaacaag accatcgtcc agtaaagaga cgcaataaat tctatcgaag
      181 tttacgcact gcctctacca cgattaaagg catggaagcc attcgaggat tatataagaa
      241 aacccgaaaa gaaggcactc tcttcgggtt ttcggtctgt actgaaatca aggtattatt
      301 gggaatccca gcttaaatca tagataccgt aagggatttt attctt
//
LOCUS       DAKCAA010000208          345 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000208 DAKCAA010000000
VERSION     DAKCAA010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.216"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..298)
                     /locus_tag="OUE31_002875"
     CDS             complement(<1..298)
                     /locus_tag="OUE31_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223790.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDT"
BASE COUNT           86 a           76 c           75 g          108 t
ORIGIN      
        1 acgtgtcatt cgtccgtcta taagcaggaa cagtctgttg cttgaactca ccattgcggt
       61 cgcgcggaat ctggagatga agttccccat actcggtctt gaccgtacgg tcataggagc
      121 cgttacgaga attacccgtg ttaaaaccaa tgcgatcata cttttcgtaa tctaggaaag
      181 ccgttaactc cgttttgaga agcgtattga ctgctttctc caaatggaca cggaataatt
      241 cattcaaatc gcctttgttc gctagagtct ttagaatttc tgtagtaaaa tcgttcatag
      301 ggaagtcctc tcttctgtga atgtgttgtg gtaactctat tctac
//
LOCUS       DAKCAA010000209          334 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000209 DAKCAA010000000
VERSION     DAKCAA010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.217"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..>334
                     /locus_tag="OUE31_002876"
     CDS             <1..>334
                     /locus_tag="OUE31_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCU0223791.1"
                     /translation="SVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSA
                     KTDLVDEHHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRM
                     NFLPTVLC"
BASE COUNT          103 a           71 c           73 g           87 t
ORIGIN      
        1 gatcggttcg tattatccgc aacggttcct atacgacacg cactcagatg ttgaaagtca
       61 aagaaaagtt aactatttta gaattaaaac gtacccgttt tctctgccat gattgtggaa
      121 ggaccttttc tgcgaaaacg gacttagttg atgaacatca tcaactaaca aaggaactga
      181 agcaggcgat tctcatggaa ctgtacgaaa atcaatcacg taaactaatc gctaagaagt
      241 acttcgtctc ggatgggacg gtgacacgga tcttgcgtga agcaacgaag cattaccagc
      301 cacgtatgaa cttccttccg acggtgttgt gtat
//
LOCUS       DAKCAA010000210          325 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000210 DAKCAA010000000
VERSION     DAKCAA010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.218"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..>325
                     /locus_tag="OUE31_002877"
     CDS             <1..>325
                     /locus_tag="OUE31_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223792.1"
                     /translation="SFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTI
                     HIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLY
                     GWNVT"
BASE COUNT          100 a           52 c           78 g           95 t
ORIGIN      
        1 tttctttctt agggaaagta caaatggaag tgattagtgc actgttgcaa gaaaagtatc
       61 atgtggagat agaactaaaa gagcctacag tcatttatat ggagagaccg ttaaaaaatg
      121 cagaatatac cattcacatc gaagtgccgc caaatccttt ctgggcttcc attggtttat
      181 ctgtatcacc gcttccgttg ggaagtggaa tgcagtatga gagctcggtt tctcttggat
      241 acttaaatca atcatttcaa aatgcagtta tggaagggat acgctatggt tgcgaacaag
      301 gattatatgg ttggaatgtg acgga
//
LOCUS       DAKCAA010000211          323 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000211 DAKCAA010000000
VERSION     DAKCAA010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.219"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="OUE31_002878"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="OUE31_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HCU0223793.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT          100 a           49 c           51 g          123 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatatc aactcatttc ttg
//
LOCUS       DAKCAA010000212          316 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000212 DAKCAA010000000
VERSION     DAKCAA010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.denovo.220"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            28..>316
                     /locus_tag="OUE31_002879"
     CDS             28..>316
                     /locus_tag="OUE31_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HCU0223794.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCR"
BASE COUNT          109 a           52 c           70 g           85 t
ORIGIN      
        1 taaacaactg agaggacgat atgctatatg aatgattcta tcaaaaaaat gctgcgatta
       61 atagagaaag atttgatgat tacagaggtc tcttacgaga cctttcagaa gaaaaagacg
      121 ttgatcgtcg atgctgtttt ctcacctgct ccccatacct gtagaaattg tggttctact
      181 gtggtagatg gaaacgggaa agtaattgta gtgaaaaatg ggaagaagga aacgattgtc
      241 cgctttgaac aatacaatca catgcctttg gttatgcgct taaaaaagca gcgctatacc
      301 tgtaaaaact gtcgaa
//
LOCUS       DAKCAA010000213        13508 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.guided.066, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000213 DAKCAA010000000
VERSION     DAKCAA010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.guided.066"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            complement(<1..866)
                     /locus_tag="OUE31_002880"
     CDS             complement(<1..866)
                     /locus_tag="OUE31_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCU0223795.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQK"
     gene            992..2113
                     /locus_tag="OUE31_002881"
     CDS             992..2113
                     /locus_tag="OUE31_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCU0223796.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            2371..3873
                     /gene="eat(A)"
                     /locus_tag="OUE31_002882"
     CDS             2371..3873
                     /gene="eat(A)"
                     /locus_tag="OUE31_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCU0223797.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            3901..4467
                     /locus_tag="OUE31_002883"
     CDS             3901..4467
                     /locus_tag="OUE31_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCU0223798.1"
                     /translation="MVKENFVNEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQALAEKVVDLPVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELISYE"
     gene            4679..5740
                     /locus_tag="OUE31_002884"
     CDS             4679..5740
                     /locus_tag="OUE31_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCU0223799.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            5743..6639
                     /gene="murQ"
                     /locus_tag="OUE31_002885"
     CDS             5743..6639
                     /gene="murQ"
                     /locus_tag="OUE31_002885"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCU0223800.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            6653..8635
                     /locus_tag="OUE31_002886"
     CDS             6653..8635
                     /locus_tag="OUE31_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCU0223801.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(8705..9151)
                     /gene="nrdI"
                     /locus_tag="OUE31_002887"
     CDS             complement(8705..9151)
                     /gene="nrdI"
                     /locus_tag="OUE31_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCU0223802.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            9362..10786
                     /locus_tag="OUE31_002888"
     CDS             9362..10786
                     /locus_tag="OUE31_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCU0223803.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(10963..11736)
                     /locus_tag="OUE31_002889"
     CDS             complement(10963..11736)
                     /locus_tag="OUE31_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCU0223804.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(11733..12638)
                     /locus_tag="OUE31_002890"
     CDS             complement(11733..12638)
                     /locus_tag="OUE31_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCU0223805.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(12799..13119)
                     /locus_tag="OUE31_002891"
     CDS             complement(12799..13119)
                     /locus_tag="OUE31_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HCU0223806.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
BASE COUNT         4283 a         2430 c         2886 g         3909 t
ORIGIN      
        1 tatttttgtc cttttcgcca aacggcacca ttgatgtagt cgatttcagt caaacgatgg
       61 tttttgatca ggtcttggta catagatggg taatgcaacc cgatgttgtc aggatcataa
      121 gtagaagcaa tatgttggta cacttcttct tgatctaatg tgattccttc ttttgctgcg
      181 atagaagcaa actcagatac aatcgttcga accatgccct ctgccgcttt ttgcgcacct
      241 aattcagcaa tattacaatc caatatcgtg cataatccat ttaatgttcc gtttacacaa
      301 gcttttcgcc aaatggaata acgaacatta tgactataga ttggattcaa ttttgcttct
      361 tgaaagactt ctacaacttt ttttgtaaat gcttcgcctt ctggttccaa gttctctagt
      421 tcgatttctc catcacctaa taatgtgact tttccgggac cagctagacc agctgtccac
      481 atcgtgatcc caaataagat atttttcttt ggtacatatt tttccagtac atcttcatga
      541 cctaatccat tcagtaaaca caaaacataa gtattctcag taataatgga ttggatcgaa
      601 cgaaacatat catctaattg attcgctttt gtcaaggcta cgatcaaatc cacgtgtttg
      661 ttgctttcga tgatttcttc tggtgaatag attggcagtt ttgcaactac ttctttgcca
      721 ttaaagtcag caatcaatcc atttgtacga atggcttcaa tgtgagcagg ccagcgatcg
      781 atcaagacga cctcatttcc gctttgatgc aacattaatc cgattcggct gcccattgct
      841 ccggctccag ctattgcgat tttcatgttt tttctctcct ttattcaatg agttcccttt
      901 tagtatatag aaaaacagaa gaaaatagca ttgttttgtt tgaaaaaagt gaaaaaaagt
      961 gtcttactta agaagaaagt gagggatata gatggatatt ttggcggcaa tcgattcatt
     1021 taaaggaagt gcttcttcat ttgaattaaa tcaggcagtt ctaaatggtt gggaagaccg
     1081 taaaggaaga aaaatcaatg tgccgattgc agatggcgga gaaaatactg cagaagcaat
     1141 ctattacgcg ctcgggggaa cctggcgtac gattgatggg atggatctct tatttcgtca
     1201 gcgaaaaatc agttatttat tgacgaactg gcaaggaaaa aataccgcag tcattgaatc
     1261 tgcacaagta ttaggattag atttacttga taaaccaacg gatcaaacca tccgacttgc
     1321 ttctagttat gccttgggag agcttatcaa agatacactg cttcaagaag tggaacaaat
     1381 cattgtcact ttaggaggaa gcggatgtag cgatggtggt ctaggattac tccaatcttt
     1441 gggtgcttct ttagaagggt acacagaagg aaatcctttg ttatctacta gaaaacttca
     1501 tttggatcga aggaacgttc ttgtttctaa agtaaaagtg atcatcgctg cagacgtgac
     1561 caacccatat acaggtcaac aaggagctgc ttggcaattt ggaagacaaa aaggaggaac
     1621 ggatacgacg ttagctttct tggataaaca agctgaaaag attgctcagc agataaaaga
     1681 tgtttgggag gtggatttag atgacatccc aggaagcgga gcagcaggcg gtattggcgg
     1741 agcccttttt ttgttaggag cgaagatggt ctctggtttt gagttggtca gccaaatcac
     1801 tggattagaa aaacagatcg aacaagcgga tgtcatcatt acaggagaag ggcggattga
     1861 tcagcaaaca atccacggaa aagttccata tggcgtagca gtgcttgcaa aaaaatatcg
     1921 aaaaccaata atcgctattt gcggaagtag agaccgagag ctggaaggac tctttgattt
     1981 tctccccatt gtcttaagca ttcaattagg accaatcgat ttagaggaag caatggaaca
     2041 caggcaaaca ttagaaaaaa cagaaatctt aggacagaca ctcagcagat ttttcaacat
     2101 tctcccgaag tagttgacaa aaacaatttc tttatgctat cgtaatttca aatataggac
     2161 aaagtgaggg atccgtgcat tgaaaaatta agtcgattga tgaaagctgc attcagactg
     2221 taccttgtgg agacaaggga gcagtgtgca gattttcggg attggcttgg ttctttcgat
     2281 gtatgggtct ttttgtgtgc cccaaccctt gcatcctctt tagccagttc tgaaaatagg
     2341 actggtcttt ttttacgagg tgatggaata atgtctaaaa tcgaaataaa aaatctgaca
     2401 ttcggctatg acagccaagg cacattatta tttgaacaag ccaatctaaa ctttgacaca
     2461 caatggaaac taggacttat cggacgaaac ggtcgaggaa agacaacttt actgaatatc
     2521 ctgcaaaaca aactccctta tcaagggcaa gtgatccatc agcaagcgtt tgtctatttc
     2581 ccgcagcaaa caaaagataa agagcgtttg acctattatg tgttaaatga gattatggat
     2641 tttgagatat gggaaattga aagagagctc caactgatgc aaacagatcc tgaaatctta
     2701 tggagagaat tcagcacact atcaggagga gagaagacaa aagtcctact ggcactctta
     2761 tttgtggatg acactcattt cccgttaatc gatgaaccaa cgaatcattt ggatatctct
     2821 ggcagaaaac aagtagcggc ttacttgaaa aagaaaaaac aaggattcat cgtggtgagt
     2881 catgatcggg gatttatcga tgaagtagtg gaccatgttt tagcaatcga aaagagccaa
     2941 ctggaacttt atcaagggaa tttctctatc tatgaagaac agaaaaaact tcgtgatgaa
     3001 tttgaaatag ctaaaaatga aaaattgaaa aaagaagtca gcaggctaaa gaaaacagca
     3061 gctgaaaaag cagaatggtc tcgttcccga gaaggggaca aaacaaagaa aaaagtcgga
     3121 ttcatcgata cggaatctag gcgagtgaat aaaggagcag taggcgctga tgctgcacgg
     3181 acgatgaaac gatctaaagc aatcgtgaat cggatggaaa cccagatcag tgagaaagaa
     3241 aaattattaa aagatatcga gtatatcgat gctttgacga tgaatagcca agtgtctcat
     3301 cataaacggc tgttaagcgt agaaaatctt caattagggt atgaaaatct gttattcgag
     3361 ccagttcatt ttacgatcga acctcatcag cggatggcaa tttcaggtcc taacggcgcg
     3421 ggaaagtcat ccattatcca ttatcttctg gggacattca acggcaaggt tgtaggagaa
     3481 aaatcccagc ccaaacattt gaccattagt tacgtacgcc aaaattatga agacaatcga
     3541 gggacattgg cggaattcgc gaagaaaaac cgagtagact atcaagcatt tttgaataat
     3601 ctccgaaagc ttgggatgga aagagatgtt tttcataata aaatcgaaca gatgagtatg
     3661 ggacaacgga aaaaagtgga attggctaaa tctttatccc aaccagctga gctctatata
     3721 tgggatgaac cattgaatta tttggatgtc ttcaatcaag aacaattaga acaactgatt
     3781 ttgaacgtga aacctgctat gttactagtg gaacatgatc aaacctttct agataaagta
     3841 tctactgaga ttatttctct tgagaaaatc taaaccttgt aatctcaaag acaacaaggt
     3901 atggttaagg agaactttgt caacgaagga gagaatcaca tgctttatgt aacgagacac
     3961 ggagaaacaa cttggaacgc acaaggatta gtttgcgggc gagcagatgt gccgctgact
     4021 gaaaaaggac agatgcaggc acaggcacta gcagaaaagg tagtagattt gcctgttcca
     4081 atcacgaaaa tcatccattc ccctcttcaa cgagcaagag atacagcaca agcagtagtt
     4141 gatcgtctca atttgccgat gaccgctgat gagcgattgg tagaaatgga ttttggggat
     4201 tatgacggac tgccaagcaa agatgaaaac tttcaaaaag cgcgtttagc gtttgctgta
     4261 cgtttcccaa atggagagtc ggtcttagat gtgtacgcac ggatcgttcc tttattgaaa
     4321 gaatgcatgg aagacgaaga aaatgtctac ttgttagtct gtcataatgc cttgataaga
     4381 gtgatcaatg cttattttca tccaatgcct aatgaagggt tctttacatt catggtagac
     4441 aatacagaat taatttctta tgagtaatta gacttttgtg ttatttaaat aaaatgtttc
     4501 aaggcactgc ttttgcttag cagtgccttt tttgtggctg tgtcaattct tttggcatta
     4561 taaatccaat ttttagaaat aaaatttaat tattttaaca aaagtattga aattttgttt
     4621 ctttagatat atactctagt catagaaatg aagacggata cagaaaaaga gggataatat
     4681 gtttggcttt tcaatattta tgaatgattc tttgtcagaa gagaagaaac agtatatccg
     4741 ccaaatggca tccaatggct ttgtcggtat tttcacttcc atgcatatac cggaagatga
     4801 tgtttcggct tatcaaaatc gattgatcga actaggaagc gaagcgaaaa agaataaact
     4861 agagttgatg gtcgatattt caggagaggc attgaaacga gctggctttt cattagaaga
     4921 tctaacaccc ttgaaagcaa ttggtgtaac agggttaaga atggattatc atatttctaa
     4981 tcagcagatc gccgactggt cacatcaatt gaaaatcagt ttgaatgcca gcacgatcac
     5041 gcctaatgat atcgatgagt tgaaagaagc agcggctgat ttctcacaga ttgaagcttg
     5101 gcataattat tatccacgtc ttgaaacagg gttggacaaa gaatggtatc aggaaaaaaa
     5161 tcaatggctc aaaactcaag gattccttgt acaaggcttt gtaccaggag atacagagtt
     5221 gagaggtcca ctgtatcaag gattaccaac tttggaagaa catcgaggga tccatcctct
     5281 ggcaggtgct cttgatctat tagcaagtaa cacggatatt gtttatatcg gagatgcagg
     5341 tctgtcagaa cacgttcagg agcaatttgc ttctttccaa aaagaacaga cagtcttgct
     5401 ccatacggaa cctgtagatg aagtttttta cgaatatata ttaggaaaac atacgaatcg
     5461 gcaagatgat gcaagagatg tcatacgaag cgcagatgcg cgttttcgag agattccgcc
     5521 aatcccagta agaaatacag ctaagcgtat gaaaggatct attactttag ataacgaaaa
     5581 gtatttgcgc tatatgggtg agatccaatt aactaaatat gatttgccag cggatgaaaa
     5641 agtgaatgta gtagccaaag tcatcaaaga agaactaccg ctgatcaacc aaatcaaagc
     5701 tggtatgaac tatcaattta taagaaaaga aggaagataa aaatgagcaa aatcaattta
     5761 gagaacctaa caacggaacg cagaaaccaa gaaacttttg gattagatga aatgagtatt
     5821 tctcaagcag tccaactcat gaacaaagaa gatcagaaag tggccgctgc tgttgaaaaa
     5881 gaactgccaa gtatcgagcc agtgatcgcc aacacgattg aatcctttaa aaaaggtggt
     5941 cgcttgattt atatgggagc tggaacgagt ggtagacttg gtgtattaga tgctgctgaa
     6001 tgtgtaccga cattcggtgt agaaccggaa atggtcatag gcctaattgc tggtggagaa
     6061 gaagcaatga ctgtagccgt cgaaggagcc gaagattctt atgaattagg gcaagaagat
     6121 ctaatcaagc tgaatttaac aaaaaatgat atagttattg gtatcgcagc tagcggtcgt
     6181 acaccatatg tgattggtgg attagattac gcaaaatcga ttggtgctgt tacaggaacg
     6241 atttcttgca ataaacaagc agaaatcagc gagcatgcgg atttcccaat cgaagtcgat
     6301 gcaggaccag aatttttgac aggctctact cgattgaagt caggaacagc acaaaaactg
     6361 attttgaata tgatttctac tatcagtatg atcggtatcg gtaaagtatt caataacttg
     6421 atggtcgacg tcaaaccaac aaatgaaaaa ctaattgaac gctcaaaacg aatcatcatg
     6481 caagcgacag aagctgacta cgaaacagct gaaaagtact ttgaggaagc agatcaaaat
     6541 gtcaaactgg ctatcgtcat gattttgaca aatagtgata aagaggcagc tcaagcaaaa
     6601 ttagctgaag caaacggttt tgtaaaagga accttatgag ggggaaaaga ccatggcaaa
     6661 aaacgaattg actttggaag aactggcaaa acaaatttat caaggagcag gcggtatggg
     6721 caatgttgaa agcattgtcc actgcatgac tcgtgtacgt atgaaggtca tcaatgatga
     6781 tcttgtaaat gtctcggaat taaaagcgat tccaggagta cttggcgtag tagaggatga
     6841 acagctccaa gtcatcatcg gacctgggaa agtgaacaaa gtagcgcagg aaatggttga
     6901 cttagcaggc gtgaaattag gagaaaaact tccttctgct agtgcaacta cagcaagttc
     6961 ttctgcatct ggaaaagacc gtgtaaacga acgggcacaa gaaatgaaag cggcacaaaa
     7021 atcgaaacaa aaaccctcta aaatcaaatc ggtattaaaa gacatctcta atatctttgt
     7081 accaatgatc cctgcatttg tcggcactgg gatcgtggca gggattgccg cagttttagc
     7141 aaacttagtc acagctggaa cactagacgc aggaacatgg caacaatata tcgatgtgat
     7201 gaacatcttg aaaaacggga tgtttagcta tctagttatc tatacaggta tcaatgctgc
     7261 acaagttttt ggtgcaacgc caacgcttgg tggagttatc ggggctgttg tgatgctgac
     7321 agggatgaat ccagaagcac cactgaaaaa cttgtttacc ggtgaagctc ttgcaactgg
     7381 acaaggcggg atcttaggtg ttatcttcgc agtttggtta ttgtcaatcg ttgagaaaaa
     7441 actgcataaa gtagtacctg atgcggtaga tatcatcgtt acgccaactc tttccctgat
     7501 tgccatcggt ctgatcgaaa ttttcttcat catgccttta gcagggttca tttctgacgg
     7561 catggtcggt gggatcaact gggtacttgg tgttggagga gcatttgccg gcttcgttct
     7621 aggtacatta ttcttgccaa tggtcatgtt cggactacat cagatcttga cgccaatcca
     7681 tgtacaaatg attgatgaaa ctggtcgtac cttattgctt ccaatccttg cgatggccgg
     7741 agcaggacaa gtgggtgcag cattggcatt atggatccgc tgcaaaaaag acaaagaatt
     7801 aacagaaatg atcaaagggg ctttaccagt cggaatctta ggaatcggcg aaccattgat
     7861 ttacggagta acattacctc taggacgtcc atttattact gcttgtatcg gtggaggtat
     7921 cggtggggca gtgatcggaa tgatcggaaa tgtcggagca atcgctattg gaccttcagg
     7981 agccgctttg attccattga tctctgatgg taaatggtta ggctatatcc ttggtttatt
     8041 ggctgcttac gctggtggct tcgttgctac attcttcttc ggtattccta aagaccgttt
     8101 agaaaaagaa gaactagcga ccgaaacagc cacagtaaat gaagtacctg aaaaagcagt
     8161 acctcaagct tcagctgaaa gtgtgactat cttatcatca gttgctgacg gaacagttgt
     8221 ttctttagat aaagcaagtg acccagtttt tgcacaaaaa atgatgggtg aaggttactt
     8281 tgtagaacca gaaaacggac atatctattc cccggttact ggagtaataa gttctgtttt
     8341 cccaacaaaa catgctatcg gcattacgac accaaatggc ttagaaatct tgcttcacat
     8401 gggcatcaac acagttgact taggcggtac gccattcgat gtgaaagtaa cagaaggaca
     8461 gcaagtgaca cctgatacgc ttgtagcaga agctgactta gaagcaatca aagcagcaga
     8521 caaagaaacc tccatgatcg tcttggtaac caatatggat cgtgtaaaaa actttgtctt
     8581 ggaaaaaaca ggtaaagcga aagcaaaagc acctgtgatg gatgtcaaag cttaataaga
     8641 atagaaacaa tagagaacat aaaaagaaga agccgaaatt tatttttcag cttcttcttt
     8701 tgtgttattt atttttttct gccaaaattt gataaacgcg tgtcacatca gatggtgttc
     8761 cccgtaattc ataatctgcc aagaaaggaa agccgaatct ttgtgcgtat tgtttggctg
     8821 tcagacaata ttgattgttg aagtttttat taccgctacc gactacacca aggcaaagtt
     8881 tatgattgtc ttcgtattcc agatattcgc gcatcgtttc ggtcaagatt tctgtgtcac
     8941 cgttgtctaa cccattcccg ccgtctaaat aagtaggaac gaaagtaaaa aatggttctg
     9001 tttctttcgt aaaatcacta ttttcatgga tttcttttaa agtaacttca ggattgacag
     9061 gatcttctgc atgcattttt tcagcatatt ctgctagatg tttggcaaaa gcacgcgtat
     9121 ttcctgaaat cgatatatat aaaatgttca tggatcatcc cccaattctt tccctttagt
     9181 atagcatctt tttaagtttt tttggtggtg taatttggaa agggactagg cgctttgctt
     9241 gtataatgag aaaaaagtcg gtagaattat atttctatta aagtttttat taattaagta
     9301 aaaataaaaa aggtttgtta tactttttga taaaagcggt tttactttgg aggatgctta
     9361 catggataca gagcaacaga aaaaaggaat tggtttgatt ccacttgctg ccttagtgat
     9421 tggttcagcg attggaggtg gcgtatttgg tattatgacg gacatctccg gatcggctgg
     9481 tggcccagct atcttcagct gggtactcgt aggaacagca atgttgatgc tctccttatc
     9541 gatcaataat atcaataaaa aacgtccaga tttaaaaggc gggatcttta gttacgcaga
     9601 agaaggtttt ggccgtttcg ctggttttat cagcggttgg ggttactggc tcacatgctg
     9661 gttaggaaac gtggcgttcg caacattgtt gatgagtgca ttaggttatt tcttccccgt
     9721 attcgaaggt ggtcaaaatg tggcatcgat cgtgatgagt acgatcttct tatggggata
     9781 tgcatggcta gtgaatcgtg gagttgaaaa tgctagcttt gtcaatgcta tcgtcacatt
     9841 ttgtaaatta gtgccattat ttttatttat tgtagtagct atcagcacct tttcgatcca
     9901 acaattcatt aataactttt ctagcgatat catattgaat gcgaatgggc agccgatccc
     9961 gttttctagt caagtattga gttgcatcat ggtgatgctc tgggtattcg ttggtattga
    10021 aggagcttct gtcgtaggtt cacgagcaaa aaaacaatcg gatgttggga aagcaacgat
    10081 tctaggaata ttcggtttga tcattattta cgtcttggtt tccatgcttc catatggcac
    10141 aatgacgatg aatcagctgc aaacgatcaa agcgcaacct gctatgggat atgtatttga
    10201 aatgatggtt ggtaaatggg gggcggtcgt gatcaacggc ggtttgatca tttctttagt
    10261 tggggtttgg ctctcatgga caatcttgcc gattgaaaca atggggaata tggctgagga
    10321 cggacttttg cctaaagcat ggggaaaact caacaaaaat ggggcaccaa cttatgctat
    10381 cgtattgacg acgttatgta cgaatgtctt tttactttca ttattattca ctgacagtgc
    10441 atataacttt gcttatacac ttggtacagc agcgattttc ttcacgtggc ttttcttagg
    10501 gctgtaccaa atgaagcttt cttatcagcg gaaagagtgg gtccaatttt tagtagggtt
    10561 tttagcaagt gcttttcaag tatgggccat gctagttgta gcctttaatg aagtgatgct
    10621 tgttcttgtt cttttcttac caggtattta tttttacctc aaagcacgta aagaacaaaa
    10681 cgaacctgta caacatatcc acttagataa gattttactt atcggtgtga cgatggtcgg
    10741 agtaatcgca atggttttat ttgccactgg gatgcttcac gtatagaagt ataaagagag
    10801 gctgtgaagc ctgtggttta ttcaaaaaag aagcggtgac aacattcgtg tcatcgcttc
    10861 tttttttgaa taaatggtgt tcaagaagta gcttcttcta aaaataagcc gaaatttctt
    10921 gaaactggcc acttctgtca caacttcttt gttaatgaac catcatacat tttttcgctt
    10981 gaatacgagg tatcccaatg ctaagaacaa agcaatgtaa gctaaattgc caaacagcat
    11041 ttgattagta gaaagatgag tcaattgctt cataatctct tcgttgccaa tttggttttg
    11101 cagattcagc atactgattg gattccattt gatccactcc catttttgaa tgagtgcgat
    11161 gaggatacca gatatgattg atgaagcaaa ataaaagacg atccctgctg agatggaggc
    11221 accggaacta ttgataaaac aagcaatcat caacactaaa cttaaaatta gccataaacc
    11281 gatataacta cccaaagtat aagtgaataa gctttggatc agtgtctgac cagtagaaat
    11341 cttctccgta aaggaaatcg aagggaaaag gatcagtttc atcagcacgg tgacaataat
    11401 agctaaaagg tataaataaa tagaataaat aactaatgtg atccatttac ttactaatat
    11461 ttctcctcga gaatactttc gataaaggag atttttcaat gtaccatatt gtgattccat
    11521 tgaaatgatc gtacttgcag cagcaatcat gataaagaca atccaagatg tggcactgaa
    11581 aagctgagca gtcatttcaa ctggatcaat gatcgtcgtg tattttttgg ctagaagtgc
    11641 tgttcctatg agcaaagcaa ctaatagaac agataaaaca gcagttgact ttttcttgat
    11701 caatttaaat aattcttgtt ttataagcaa cgtcattttt cttcttcccc ctttactgaa
    11761 tccagaattt ccaataggga agattccaaa tcattcgtca gatgctggac atctgtcaca
    11821 tggacatttt ctgcagacaa taactggata acagttccta ataactcttc gttttttttt
    11881 agaagcttga ttttatcagg atcttccaag ggatatccag cgtctgtcaa gatcgttcga
    11941 gcagcttgat catttgtcgt agagataacg atgaaatctt gcgctgtttg gttcaattca
    12001 gccattgtac attgtttgat gatttttcct tgattgatca ggatcagctc atcgaccatt
    12061 ttttcaagct cgctgagtaa gtgactggag atcaagaaag aggtgccctg agtagccaag
    12121 tcggtaatga tttttcgcac atctcttgtt gcttgtggat ccaaaccgtt catcggctca
    12181 tctaaaataa cgatagacgg atggttcagt aaggcaagag caattcccaa tttttgtttc
    12241 attcccagcg agtaggattt cgcttttttg tgaatgtatt tttccatctt gagctgtttc
    12301 acgatagtgt cgatagcaga tacatcgttt gtttcagaga ataacttcag atgatcataa
    12361 cctgttaaga atggatagat acccggatat tcgatcaatg ctcctacttg ttctaatcct
    12421 ttatgactag agggagaaat ctcattttca ccaatacgga tcgttccttc tgagtaatgg
    12481 atcagtccta aaatagcttt catgatcgtt gtttttccag cgccattagg acctactaat
    12541 ccaacgattt tgccaggaga taagctaaaa ctgacatcgc tgagggcttg tttgtgacca
    12601 aagttcttgg ataattcttg gaccgaaaga cttttcaaaa atattcactc cttttctata
    12661 gatagtacaa gcatacacct gatgagtaga gaagtcgcta ggtcattagt cttattttct
    12721 tgttttttca tagaaagagg aatatcaaat aaaaagcccc gctttttctg atcagtcctt
    12781 gtctgcttgt ctaagtatct agtgaccgct agtgattttg atgccaatga tgctgatgag
    12841 cagcaacccg acaaagaacc aagtggaaag attcagctta tcatgaaaca agaccacacc
    12901 aataatgacc gaaccaactg cgccaatccc tgtccaaata ggataagaga gactcatagg
    12961 caaacttttg attgcctttg acaaaaagta aaaactagca atcattccaa tcactgtgta
    13021 aaaagaataa ttgattttag aaaaaccatc actccatttc atcatcgttg accagaatac
    13081 ttccaaaatt cctgctatga ttaattccat ccatgccata catacgttcc tccttcaata
    13141 taaaaaatac acaaaaagag gagaatcatc ccttcaaaga cctaatggaa tgatcatcct
    13201 cttttttact acccggtggc agatcgtata tctttttctg tagtatagca cacctatcca
    13261 gatatcggca atctcatact ttttagtaaa gtgtaacaag cattgacgga tatatcgtta
    13321 gcagaaaaga agatgaatgc tttgcaattt catagaaagg agttgttatt tattaatcat
    13381 ttaaaaaaac agtaactaga ccttattttt atatattagc aggcaataaa ttaaaaaaag
    13441 ctttatctta caataagtaa ggtgaattat ataatcttaa ttgtcaaatt aagttagaca
    13501 gatcatca
//
LOCUS       DAKCAA010000214         8434 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.guided.089, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000214 DAKCAA010000000
VERSION     DAKCAA010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.guided.089"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..771
                     /locus_tag="OUE31_002892"
     CDS             <1..771
                     /locus_tag="OUE31_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223807.1"
                     /translation="GDLMSLFTLQSNDSQNMGRQVFRRPRQMMNRQTRRFQRSMSKIF
                     RGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQQGGIGQRLGEKTA
                     HVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDFKQSMADTKAQRKQ
                     QRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRKRQQTVTPVLSQNT
                     KRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            768..1790
                     /locus_tag="OUE31_002893"
     CDS             768..1790
                     /locus_tag="OUE31_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCU0223808.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            1807..2736
                     /locus_tag="OUE31_002894"
     CDS             1807..2736
                     /locus_tag="OUE31_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCU0223809.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            2981..3097
                     /locus_tag="OUE31_002895"
     CDS             2981..3097
                     /locus_tag="OUE31_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HCU0223810.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            3113..3916
                     /locus_tag="OUE31_002896"
     CDS             3113..3916
                     /locus_tag="OUE31_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCU0223811.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            4151..4387
                     /locus_tag="OUE31_002897"
     CDS             4151..4387
                     /locus_tag="OUE31_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223812.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            4394..6346
                     /locus_tag="OUE31_002898"
     CDS             4394..6346
                     /locus_tag="OUE31_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCU0223813.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(6418..6915)
                     /gene="dfrG"
                     /locus_tag="OUE31_002899"
     CDS             complement(6418..6915)
                     /gene="dfrG"
                     /locus_tag="OUE31_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCU0223814.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            7277..8317
                     /locus_tag="OUE31_002900"
     CDS             7277..8317
                     /locus_tag="OUE31_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCU0223815.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
BASE COUNT         2984 a         1401 c         1591 g         2458 t
ORIGIN      
        1 ggcgatttaa tgagcctatt cactttacaa agcaacgact ctcaaaacat gggcagacaa
       61 gtgtttcgca gacctcgtca aatgatgaat cgacaaacca gaagatttca acgcagtatg
      121 agtaagattt ttcgtggaaa agcagggtca acgaagcaaa agacaatgac aacaaagcag
      181 aatcaaacca ataaagctaa ccatactcgt caaaatgaac ggactacacc aaagaaagaa
      241 acagcacttt ccaatgtgaa aaagcaacaa ggcggtatcg ggcaacgatt aggtgaaaag
      301 acagcccatg tattggacac gaaaaatcgt ctagtcaata aaagaaagca ggcaaaacaa
      361 cagatacagg cgacaccaac ccatgtcaaa tatgcccttc atcaaggaaa agagaatgtc
      421 actcataatg taacagactt taaacaatct atggcagata ccaaagctca acgcaaacaa
      481 cagcgtatga accagcagga gcaaaaacga aagaacattg ctcaaaagcg tttggagctg
      541 gataaagcaa aagaaaaaag acgaaaagaa aacccatcat ctcctgttca gaataaccag
      601 cagcatgttc gcaagcgtca gcaaaccgtc acgcctgttt tgtcacaaaa cactaaacgt
      661 gaaaatcatc agcgaccatt gaaaaaagag caaaaacaaa agacaccacc gaagcaattc
      721 aatcagagga agctaaataa aagaacggat aagcgaggac aacaaacatg aagctaaaaa
      781 taacagtgat ttgtagtgtg gtcttctctc tcttcttttt tctcttatta ttcctagtca
      841 ttttctttgc agatgatacg gacagtggcg aaaacaacaa ggattcttct attccacaag
      901 gcggtgtgac cgtttcacca gaagtgttgg cacaccgtcc gttgattgaa aaatatggta
      961 aggaatatgg gattgaagac tatgtttctt atatcttagc cattatgcaa gtggaatcgg
     1021 gcggtacagc agaagatgtt atgcaaagtt ccgaatcttt gggtttaccg cccaacagtt
     1081 tgagtaccga agagtccatc aaacaagggg ttaaatattt cagtgaatta ttaaccagtg
     1141 cagaacaaca aggagtggat atagattctg ttatccaatc ttataattat ggcggtggct
     1201 ttttaaatta tgtgaggagt catgggaaaa aatataccta tgaattagcc gaacagtttt
     1261 ctaaagagaa gtcgggtggt caaaaagcag actatcccaa tcctatagcc atacctgtga
     1321 atggtggttg gcgatataac tatggaaatc agttttatgt tcagttggtt tcacaatacc
     1381 taaccgacac ttccccaaca gaatttgatg atgaaaccgt gcaagtcatt atggacgaag
     1441 ccttgaaata cgaagggttt ccctatgtct ttggaggggc gtcgcctacc acctcttttg
     1501 attgtagtgg cttaatacaa tgggtgtatg acaaagctgg catttctctc cctcgtgtcg
     1561 cccaagatca gtatgacgct acgcaagaaa tctctatgga agaagcccaa gcaggcgacc
     1621 ttatcttctt tcattcaacc tataatgcag gcacatatgt gactcatgtg gcgatatatt
     1681 tagagggaaa tcgcttttat catgcaggcg acccaatcgg ttatggcgac ttaagcagtc
     1741 gttattggca agaccatctg attggggcta gacgtgttat tcataactaa gaaaggaatg
     1801 aatcaaatga ttataaaaat cgagcgaaaa gaaaagaagg agaaaccaaa gaaatctaaa
     1861 aaaccgagca agcaaagaaa agttccgatg attaaagttg gcacgcataa gaaattaacc
     1921 tttgttttat gggttttatt gattggtagt gtcggatttg gaatctataa aaattttact
     1981 gccattgaca ctcatactgt ccgtgaaaca gaaatcatta aacagcagat tgtcgatacc
     2041 aaccaagtag aaagttttgt gaaatccttt gcgaaagact acttttcgtg gcaacaatcc
     2101 caagaagcca ttgataaacg aaatgaaaaa ttgacccatt atttgacgga agaattgcag
     2161 gtattaaatg aagaaatgat tcgtaaggat attcctacta gttctagtgt gaacgatata
     2221 caggtgtggc aggtttctca agtgaatgag aacacctttg aggtactgtt ttctgttgaa
     2281 caagttatta ccgaagacaa agacaaggaa actatatcgt ctagctttca tgtggttgtc
     2341 catatagatg aatcagataa tatggttatt atcaaaaatc cgacaatgag taagaaacct
     2401 caaaaatcgg actaccaacc caaacagcta gaaagtgacc atacagtaga tacagaaacg
     2461 atggacgaaa tcactagctt tttagaaacg ttcttccagc tctatcctac cgccacagaa
     2521 aaagaattga cttactatgt aagtaatcat gtgttaccta tgattaacaa ggaatatgtt
     2581 ttcgaggaat tggtgaatcc tatctttacc agaaaagata accaagtaat cgtgaatgtc
     2641 gctgtgaaat atttagatca agaaacaaag gcaacccaaa tctcgcaatt tgagttgata
     2701 ttagaaaaac aagataattg gaagattgta aaataacaaa tattggtaca tgattacaga
     2761 tactttgtaa tcatgtactc tttttgataa aaaattggag attcctttac aaatatgctc
     2821 ttacgtgcta ttatttaagt gactatttaa aaggagttaa taaatatgcg gcaaggtatt
     2881 cttaaataaa ctgtcaattt gatagcggga acaaataatt agatgtcctt ttttaggagg
     2941 gcttagtttt ttgtacccag tttaagaata cctttatcat gtgattctaa agtatccaga
     3001 gaatatctgt atgctttgta tacctatggt tatgcataaa aatcccagtg ataaaagtat
     3061 ttatcactgg gatttttatg cccttttggg tttttgaatg gaggaaaatc acatgaaaat
     3121 tattaatatt ggagttttag ctcatgttga tgcaggaaaa actaccttaa cagaaagctt
     3181 attatataac agtggagcga ttacagaatt aggaagcgtg gacaaaggta caacgaggac
     3241 ggataatacg cttttagaac gtcagagagg aattacaatt cagacaggaa taacctcttt
     3301 tcagtgggaa aatacgaagg tgaacatcat agacacgcca ggacatatgg atttcttagc
     3361 agaagtatat cgttcattat cagttttaga tggggcaatt ctactgattt ctgcaaaaga
     3421 tggcgtacaa gcacaaactc gtatattatt tcatgcactt aggaaaatgg ggattcccac
     3481 aatctttttt atcaataaga ttgaccaaaa tggaattgat ttatcaacgg tttatcagga
     3541 tattaaagag aaactttctg ccgaaattgt aatcaaacag aaggtagaac tgtatcctaa
     3601 tatgtgtgtg acgaacttta ccgaatctga acaatgggat acggtaatag agggaaacga
     3661 tgacctttta gagaaatata tgtccggtaa atcattagaa gcattggaac tcgaacaaga
     3721 ggaaagcata agatttcaga attgttctct gttccctctt tatcatggaa gtgcaaaaag
     3781 taatataggg attgataacc ttatagaagt tattactaat aaattttatt catcaacaca
     3841 tcgaggtccg tctgaacttt gcggaaatgt tttcaaaatt gaatatacaa aaaaaagaca
     3901 acgtcttgca tattaagtag ttcagttttg gagtacaaaa agtgaaaatg taaacctaaa
     3961 tgagtatcaa attgcaactg aatttgatac tcgtttttta ttgttaaatc aacgtttgtt
     4021 gttaatttac accacaaaat gtaagttaaa atgtatataa aaatgcgaac gtgaaataat
     4081 tattgtagga atgcaaattg gtgtgttaaa atggttacaa tttactaagc aaaaaggggt
     4141 gcattttcct atgcaatttc ttgagccaaa aaataagaac gctaagtctg tggattggga
     4201 aatatcagag caagtaaggg tgatagttaa gcaatacgct gaatatgcag agcgtactga
     4261 aagcgaagca gtggatgaat tcttattgaa cattttagac gataagaagt ttattgaatg
     4321 gattgccaac aagcgaagta ataagcggat tgttgaaaaa atgggtatca aagatagagt
     4381 gggttgatag acaatgacca agcttaaaag attagccacg aaggaagatg aaattgtaga
     4441 tgttaaaatt ccgatttcaa acgaagaatt aaaagatagg gctaaacaat atgatttatt
     4501 aactccaaaa cgatttgcaa caaggtataa caaaatgttg ttcttgccaa cgtcttttaa
     4561 atggaacggt tctgaatatc ccattcaata taattactgc atcaatccgt tttgttgtaa
     4621 ttttgggaaa gaacagcaca aattcaaaga tgtaaaaggg aaaccaagtc gatataaaat
     4681 gactggtagt tccaaagata aaggtcataa aggtatgtac tgcaatgaca atcctattgg
     4741 cagaggtgta tcgcaaaact gtacagtaac ccctttatct aattggtctg ttgttgaaga
     4801 aattaaacgc cttatagaaa tcaatagcat ccaagatgtt gagccagatt atcaatttca
     4861 taaagaaggc tgctcggaag aagaatcaac cccattcaat gagccgaagc aattttacaa
     4921 aagggggaaa agtaggggca aatctcaacg ctatcaatgt aaggcgtgta agaagttcac
     4981 taatgttcta ccaaaaagag aagaaaccac tacttatcac caacaaaaga acaccattct
     5041 tccaatgttc gctaagatgg ttgttggaag ggtttcagtc agtcgtactt gtgatatttt
     5101 aggaattgga gttggaacct actatcataa gctggagtgg ctgtataggc gttgtttgga
     5161 gtttttagaa cgatatgaga cacaacccct tcaaacaaag aaatttaacg agatgtggct
     5221 taatacggac aagatgcact actacctaaa taacgtccgt aagaaaggac aaggttcaaa
     5281 gaaatatacg gggtttgaag accttaatat gcaaacgtat atagttgtat ctgctgaggt
     5341 cttatcaaga tatgtgttcc gttctgatgt tgcctatgat tggaatattt caatggatga
     5401 attaaatgaa gatacaagaa aattcaaaga agaccatctc aatactttta gtcgtaaaaa
     5461 tgataggtta gattggtctt attatccaca agaaccatcc gctaacgata gcgaaaatag
     5521 gaatgcttat cttcacgaat tagggaaaat tactaatagg agtagatttg tcgatggttt
     5581 aaatgttgat gctccttata ctacaactgc tcactattgg ttaattaaac aaatggttaa
     5641 tgccgacgaa tggcgaatga ttagtgatga tgacttctct attagaaacg ccttttatag
     5701 agtattcacg aaagaattaa ggttgagcga tgcacatcat tttatttgcc aagttaacaa
     5761 gacgaaaagc agaaaacaat gcttaaaaga attcggacaa gcaaaagcag aactgctcga
     5821 ttggggagat atcagaggat tcaaaacaaa gtttctacgg actttggcat ctcattatct
     5881 aactgaatta ctaacaagtc atcaattcca cgaagaggct attagtaaag atggagaaag
     5941 atatcgcaaa tatgccgata accctatcaa acatccatta gccactaagg ataaaggatt
     6001 ttattcagtt gattgtagaa cggatttatc tgctctggaa ccaaacgaaa tcgcaaagat
     6061 gctattaaat gttaatgacc attcgaccaa tagctttatt caacagataa gacgttatat
     6121 atcatctctt gaaagaccat taacaacagc tcgtggtgat aagaagagct atatttacgc
     6181 taacttcaat ccgaagtatg ctcaatttgc gattacaatt ctaagaactt actacaactt
     6241 ttgtcgccct tttaaatcag cggataaaaa ggttttgaca cctgctcaaa gattagggat
     6301 tacagataaa caatttgatt ggaaagatat aatttatttc aaatgacaaa aagagcttgg
     6361 agtaatccca agctcttgtg ctttatcttt actgttcttc ttcaattaac gcacccgtta
     6421 actcaataag ttttttcttt catatacatg aaaatagtag ttatacggat ttttatcatt
     6481 ctttatccct ttttgggcaa atacctcatt ccattcctca taattcactt ctggaaaaaa
     6541 agtatctcct tcgaattcat gatgtatttt tgtgatgtac attttctcaa cataagggaa
     6601 aaacaaatta taaatctgtt ctcctccgaa aataaaaatt tcttcttcgt ttttacataa
     6661 ctcaaaaaca tcttctattg aatgaacaat ttcacaacca ttaaaggtaa accccttatc
     6721 tctcgtcaga ataatatttc ttctgtcagg taaggctctt ccgattgatt caaggttctt
     6781 cctacctaat attatcggat gtccctttgt agtattttta acatattccc agtccttggg
     6841 aatcctccaa ggaatgtcat tctctttgcc aatcactcta ttcttatcca tcgcagcaat
     6901 caaagaaact ttcatttata acacagcctt tttaactaat ttaccatcta atttcttatt
     6961 tctatcaaaa aaccttttct cattatcctg cccgttagtt gaataagcaa ttttttctat
     7021 aagttatatt atcataatac cacaaaatca caaattttca ttcaattatc attttcaatt
     7081 gcattttata aatcattttg tatgtaattt ggtatgtaag ttaaaatgaa aaaagtagtc
     7141 cattttgaag tacattttgt cattttgtac tccaaaactg aactacttac ttgcatatat
     7201 acgcctttat agtggagtac tacatttacg agattcggtt agagtatcag aaaaagaaaa
     7261 aataaaagtt acagaaatgt atacttcaat aaatggtgaa ttatgtaaga ttgatagagc
     7321 ttattctgga gaaattgtta ttttgcaaaa tgagtttttg aagttaaata gtgttcttgg
     7381 agatacaaaa ctattgccac agagaaaaaa gattgaaaat ccgcaccctc tactacaaac
     7441 aactgttgaa ccgagtaaac ctgaacagag agaaatgttg cttgatgccc ttttggaaat
     7501 ctcagatagt gatccgcttc tacgatatta cgtggattct acgacacatg aaattatact
     7561 ttctttctta gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca
     7621 tgtggagata gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc
     7681 agaatatacc attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc
     7741 tgtatcaccg cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata
     7801 cttaaatcaa tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg
     7861 attatatggt tggaatgtga cggattgtaa aatctgtttt aagtacggtt tatactatag
     7921 ccctgttagt actccagcag attttcggat gcttactcct attgtactgg agcaagcctt
     7981 tagaaaagct ggaacagaat tgttagagcc atatcttagt tttaaagttt atgcaccaca
     8041 ggaatatctt tcacgggcat ataacgatgc tcccaaatat tgtgcaaata tcgtaaatac
     8101 tcaactgaaa aataatgagg tcattattat tggagaaatt cctgctcgat gtattcaaga
     8161 ttatcgcaat gatttaactt tttttacaaa tgggcttagt gtttgtttag cagagctaaa
     8221 aggatatcag gttaccactg gcgaacctgt ttgccagacc cgtcgtctaa atagtcggat
     8281 agataaagta agatatatgt tcaataaaat aacttagtgc gttttatgtt gttatataaa
     8341 tatggtttct tattaaataa gatgaaatat tctttaatat agatttgaat taaaggagag
     8401 tataaaatat tttgtgtaaa tgaaaaaatc cata
//
LOCUS       DAKCAA010000215         7397 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.guided.097, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000215 DAKCAA010000000
VERSION     DAKCAA010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.guided.097"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            162..1430
                     /locus_tag="OUE31_002901"
     CDS             162..1430
                     /locus_tag="OUE31_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCU0223816.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            1917..2381
                     /locus_tag="OUE31_002902"
     CDS             1917..2381
                     /locus_tag="OUE31_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCU0223817.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            2365..2994
                     /locus_tag="OUE31_002903"
     CDS             2365..2994
                     /locus_tag="OUE31_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCU0223818.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            3348..4826
                     /gene="msr(C)"
                     /locus_tag="OUE31_002904"
     CDS             3348..4826
                     /gene="msr(C)"
                     /locus_tag="OUE31_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCU0223819.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            4873..5319
                     /locus_tag="OUE31_002905"
     CDS             4873..5319
                     /locus_tag="OUE31_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCU0223820.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(5518..6033)
                     /locus_tag="OUE31_002906"
     CDS             complement(5518..6033)
                     /locus_tag="OUE31_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCU0223821.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            6150..7351
                     /locus_tag="OUE31_002907"
                     /pseudo
     CDS             6150..7351
                     /locus_tag="OUE31_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         2340 a         1269 c         1534 g         2254 t
ORIGIN      
        1 gtgaatggag aagaatattc ttcatttacg tctttttatg tagaaaaagc aaatttatca
       61 aaaagaaaca aatgttattt aaatatggac attgacttgc ttttactttt ttagttacac
      121 tgttatttag gaaaagtttc ataattcaaa ggagaaaaaa gatgaaagca aagaatttat
      181 tatttagcgt tattctttta ggaaatctag cagttgccaa cacaacagtg ctagctgaag
      241 aatcgacaga aactgtcgca actcagacat cgagttcttc agaaacagga attgaaaacg
      301 atacagagag tactttgcag tcagctactg tctcagaaaa tacaatttca accgaagaac
      361 caacaactga aacaacagaa caaacacaaa ccgaagacag tacatcagca gaagctcaga
      421 acaatccaga gaatgcagaa gaaatcacga accaattgac agatgggcaa acattgacac
      481 atacccatca agcagatttg tctgaattcg aaaactatac tggctatgct ttttatgctc
      541 gctcatctgc taattctcaa caagcgttca ttgatagtat tgcctcaact gcacaaagtt
      601 tggcaagtgc caatgactta tatgcatcag tcatgattgc tcaagccatc gttgaaagtg
      661 gctgggggaa cagtactttg gcttctgccc ctaattacaa tctatttggg attaaaggaa
      721 gctataatgg ccaatctgtt acgatgccta cttcggaata tgtgaatggg caatggatta
      781 cggtgaatgc cgcttttaga aaatatcctt cgtacaaaga atcattgcaa gataacgtaa
      841 cggtattgaa gacgacttct tttcagccag gcgtttacta ctattccggt gcatggaaaa
      901 gcaatacgaa ctcttacaaa gatgctacgg cttggctaac aggtcgttat gccactgcgc
      961 ctaattatgg ttctacattg aacaatgtaa tcgaaaccta taatctgaca cagtatgata
     1021 cagcaccaac ttcaacttct ccgatgtatc gtctgtataa ccgtcataca ggagaacatt
     1081 tatatacatt gaatgccgga gaaaaaaatt atctgccaac tgtaggctgg gaatatgaag
     1141 ggattgcttg gcaagcacca aacagcggac aacctgtcta ccgtttatac aatccttaca
     1201 gtggagacca tcattacaca atggcacaat ctgagatcaa ctctttaaca aaaatcggtt
     1261 ggcgttatga aggtctaagt ttttattctg gtggttccaa gccaatttat cgactattta
     1321 atccaaatga aaaaactggt acccatcact ataccttgag tgctaaggaa agagattggc
     1381 taacaccgat gggctggaga tatgaaggaa taggatttta tggttattaa aaagaggtag
     1441 tgaaaaagct gccctgcatc aagtagtaag aacagccaaa caaaaacaga ttttcatgtt
     1501 ttttgtttgg ttgaacttat taccgcagat gcaagttttt gaacaccgtt tactcaaaaa
     1561 aggttgtgac aacatcttgt cataactttt ttattactgt ttaagcatac tgatccaatt
     1621 tctaatattc gacgggattc ttgcaaaagg cgatttcgga aatttttggc ggtgtaaaat
     1681 tttctactgc agaagagcta tcttctatag tttgataaga atcaataatc ttggttttag
     1741 cgttgtgctt tctttatcat tttttccgtt cattctacaa aaaatttctt ttctctatac
     1801 ttttctattg agagcgtttt ttttattaca cagctgattc tttgactttt ttcttttttt
     1861 attctattat tgacaagtca atcgttgacg agtcaattat tagaaaggag gaaattatgt
     1921 ctttagaaga gattagtcac cttttatatc aaatcaaatt agccgatcaa aaaatcgtcc
     1981 agatctttga agaaaatatc ggtataagtc ttactagata cgagatcatg atgagactga
     2041 aagaagaaaa tccattgcta caaagcagtt tgcaagaaaa gttgcagatt gatcaaggag
     2101 cagttactcg tcatctgaag gtattggaag caaatggcta tgtttcgcgt cagagaaatc
     2161 ctcagaacaa ccgggaagtg tatgtagcgc taacagaaaa agcccagaag aaaatcgagc
     2221 attgtgaaat ggaccataaa gatacaggtt ccgtgctatc cccggctttc agcgatgtag
     2281 aaatgaaaca atttctaaca cttttagata aattgaatac ccaactttgc aatataacaa
     2341 cagaaacgaa agaggttaat aataatggaa caaaaaaatg atttttcaac aattatgact
     2401 ggtagaagat ccgttcgcgt atatgatgaa acatacaaaa tcccacacga agaaatgctg
     2461 gaaatgatca aagaagcgac gactgcacct tcttctgtca atatgcaacc atggcgcttt
     2521 gtggtcgctg aaagcgagga agcaaaagaa atcttgcgtc ctttgatccg tttcaatacg
     2581 agacaaaatg atacttcttc tgcaatggtc atgatttttg gcgatatgca atgttacgaa
     2641 tatggcgaag aaatctataa ccaagcttac gaatcaggga agatgccaaa agaagtcaga
     2701 gatcaacaat tagctgcgat cattccttat tacaagagtt tttcaagaga agaaatgaac
     2761 gatgtagtca aagtcgattc tagcttagcg gctatgcaat tcatgttagt tgcgcgtgat
     2821 catggctatg aaacaaatcc aattggtgga ttcgaagcag atcagttggc agaggcattt
     2881 ggtttggata aagaccgtta tgttccagtt attattttat caataggaaa agcggtagaa
     2941 gaaggttacg agtctgttcg tttagcacca gaaaagatca ctacgttcga ataaaaggtt
     3001 ttcagttact attcagtagc tattgctttt tttgaatcgt gtgtggtaac ctaataaaaa
     3061 aggaggtcgg aaaaatgact gcatcgatga aattacgttt cgaacttttg aataacaact
     3121 aaataaattc aaaagacatg tataaacaac aatttcatgg atggagtatg tccatttttt
     3181 cgaacgacag tagaataggt gaaagctatg acagatttgg tgatttagtc atagttattt
     3241 cgttcagagt aggaaaagat gtgatgcagt ttttttgcaa acagattttt ctgctctttt
     3301 ttagtatcga taattgttgt tttacatgaa ataggagtgt aaaacatatg gaaaatttag
     3361 cagtaaatat aacaaatcta caagtcagct ttggcaacca gctagaacta tctattgatt
     3421 ctcttcgtgt ctatcagcaa gatcgtatag ggatcatagg agaaaatggt gtcggtaaat
     3481 cgactttgct caaactaata gccggtgaac tttttcccga tcatgggaaa atccaaacag
     3541 agatcacctt caactacctg cctcaattaa cctatctcgc tgaagcaaag gacctaaatt
     3601 tggaattagc cagtcatttc cagttaagac tggaagaaac ttcagagcgg aaatggagcg
     3661 gaggggaaga acgaaagatc gagttgatac gtcttctttc ttcttatgaa caagggatgc
     3721 ttctagacga gccaacaacc catctagata gaaaaagtat tgatcgactg attgaagagc
     3781 ttcgttatta ttatggtacg ctggtttttg ttagtcatga tcgctatttt ctagatgagc
     3841 tagcatcgaa aatctgggaa gtaaaagacg gagaaatccg agagttttcg gggaattata
     3901 gtgcctatct cactcaaaag gaattggaga aaaagactca gctacgagaa gcagagtcga
     3961 tcatgaaaga gaaaaaacga ttggaaaaat cgatccaaga aaagaaaaaa caagcggaaa
     4021 agttggaaaa agtgtccagt aaaaagaaaa agcaacaaat cagaccggat cggttgtctt
     4081 cctctaaaca aaaagacagt gtacaaaaag ccatccaaaa gaatgcgaaa acattagaga
     4141 gaagactcca aaaaatagga gaaacaacca agccgcagca gatgaaacaa atccgttttc
     4201 cagtaccaaa atctcttgaa ctccacagcc gctatcccat catgggacaa aatgtccaat
     4261 tggaaagaag tgggagaaca ttactggtaa atggtgattt tcagttttct ttaggtaaaa
     4321 aaatcgcgat tgtcggtgaa aatggttcag gtaagacaac cttattagaa catatccgca
     4381 aacaaggaga aggaatcctt ctctctccga aagtaagctt tcaagtatat cagcaaaagg
     4441 gttatcaaat gacatctgaa gaatccatca ttcgttttgt catgagacaa acagagtttt
     4501 cagaatcgct tgtccgtagt ttgctgaatc acttagggtt tgctcaggaa actttgacga
     4561 aaccgttatg tacattaagt gggggagaag cgacccgtct gacgattgct ttgcttttta
     4621 ctaagccaag taatgtgttg ctgttagatg aaccgactaa ttttattgat atggcaacga
     4681 tcgaagcttt agagaagcta atgcaaatat atccgggaac gattttgttt acttctcatg
     4741 attcttactt tgtcgagcgt acggctgatg aagtttatga aataaaaggg cagaaaataa
     4801 aaaaagtact tacgagaaat ttttaaatgt gctacgatga ttttcgtgac aaatttaaag
     4861 gagtggtaca gattgcctac aaataaaaaa gaaggaataa tttttacaac aatgatgtgt
     4921 tttttgatgg tcttggggat gagcgcgtat aatttatggc tgcatcaaga tcttcattta
     4981 tcaagtttgt tgattggtct agtgcctgga ttcgtggtgg ctttcatttt ggatgtcttc
     5041 atcatcggtg tgctggcgaa aaaaattgcc tttaaactac cagtaaatcc agaaagcaag
     5101 gtccaaatga tcttaactat ttcatgcttg atggttttag gaatggtgac atgtatgtct
     5161 ttattcggtg tgatcatgga acaaggaata cctgatcaat tattctctgc ttatatgaat
     5221 gcttggaaaa tgaatgtgat tgccgcttta ccgttgcagt tgatcatcgt tggcccgctt
     5281 tcaagaagtg tgctaaaagc aattcaaagt aatgaatgat ggaacactgt tatttgaaaa
     5341 aaggccttgg catgcttttt gtcatagtct cttgaatgca gttctagaaa aatagtgatc
     5401 cgaacgatag gttttggcct gtcgttcgga tcgctttttc ttttccaact gtattgctct
     5461 tttattgaag ataatttgct cttcaataga tatttctaga aaggttctgt ttatccctta
     5521 ctcaaaaaac tgctgcattt gttctcttac ttgctgacac cattggagtt cctgctgaca
     5581 aagcataatt ctgcgctgga tcacaacata acgtccaaat tcttgtttct tgtctagcga
     5641 gaggtcattc aatttttttt gatttttttg catgattttg ttcagctgtt gttctctagt
     5701 gaatagcagt ccagtagctg ttgttttatc gagcgtcgaa aaagcataga tttttgctag
     5761 aaattcatct ttttgcgtag gagcgggagt ttcctctttg atccattcct ctacaagagc
     5821 acgtccttca tcagtcaagt ggtagatctt tttttgagag tgctcgtctt tgtccaaaac
     5881 ggtcacataa ccctgctggt ctaacttggc aagcgttgta tagatctgac tgtgatgggc
     5941 ttcccaaaaa attgtgatca gctgcttcaa ttcataccca gaacgtggtt tggataaaag
     6001 cacgcataat aatatatagg ctaaagtatt cataaaaatc ctacctctcg tcttattttc
     6061 tttattatat cacagtaaag tttccacgtt ttacatgtgc atatttacat gtaaaataaa
     6121 tcatgtatga tgctaataga gagaaaggga tggaaatatt ggagaatcaa atagatatac
     6181 aagaacaaac aaatgaagaa acaaagggga aaagttcagc gctagttgta gcagctacct
     6241 gtatgatcgc ttttatggga gtgggtctag tagacccaat cttaaaaacg attgctgcac
     6301 agttaaacgc tacgccagct gaaacgaccc tgttatttac tagttacatg ttagtcactg
     6361 gtgtggtgat gctatttaca ggtttcttat ctagtcggat cggtttgaaa aaacattgat
     6421 gacaggattg tttatcatcg ttgtattcgc tggtcttggc ggattatctg ggaatatcgg
     6481 aatgctgatt gggttacgtg ccggctgggg tgtcgggaat gctttatttg tctctactgc
     6541 tttagcaacg atcgtcagta ttttagttgg taacacagaa aaagcaatca tgatgtatga
     6601 agcagcactt ggctgcggaa tggctgttgg ccctctagtc ggtggggtct tgggcagtgg
     6661 ttcatggcgt tatccatttt ttggggtagc atttttgatg ttttgcggtt ttatagccct
     6721 agcggtactt ttacctgaaa ctgagaaacc aaagagaaaa gtaggccttt gggaaggtgt
     6781 caaagcgtta agcaatcata aacttcgttc agttggacta atcgcattgt tatataattt
     6841 cggattcttt actttacttg cgtatgcgcc atttttattg attggctatt ctgaattaga
     6901 agtcggtttt gtattttttg gctggggtgt gcttctggct attgcttcga ttttcgttgc
     6961 accggctctt gagcggaagt ttacgactta tcggacaatt ttagcagcat ttgtcttatt
     7021 cattatttgt ttgctgttat taggagctgg aacttctatg ccagtccttg taccgatcag
     7081 cattgtgtta gcaggatttt tccaaggaat tatcaataca ctgttgacga cgattgctat
     7141 ggaaatacca ggtctgcaac gaaacgttgc ttcgtccagc tatagttttg tccgcttttt
     7201 cggtggagct ttagcaccat ttattgcagg tgtgattggt gaacatattg gtgaaagcta
     7261 tgcgttttat tttgcaggtg ccattgttct tatcagtgta tgttgtatca tttatcaccg
     7321 taattatttt gctacaaatg aagaagaata agaaatcaga ggttgtgaaa aagctgtcct
     7381 gcatcaagtc ataagaa
//
LOCUS       DAKCAA010000216         3253 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.guided.138, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000216 DAKCAA010000000
VERSION     DAKCAA010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.guided.138"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..331
                     /locus_tag="OUE31_002908"
     CDS             <1..331
                     /locus_tag="OUE31_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223822.1"
                     /translation="AGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNE
                     VILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVR
                     YMFNKIT"
     gene            441..491
                     /locus_tag="OUE31_002909"
                     /pseudo
     CDS             441..491
                     /locus_tag="OUE31_002909"
                     /inference="COORDINATES: protein motif:HMM:NF019662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            525..1901
                     /gene="tet(L)"
                     /locus_tag="OUE31_002910"
     CDS             525..1901
                     /gene="tet(L)"
                     /locus_tag="OUE31_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCU0223823.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            2465..>3253
                     /locus_tag="OUE31_002911"
     CDS             2465..>3253
                     /locus_tag="OUE31_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCU0223824.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKGFCCKVLNLLSNK"
BASE COUNT         1043 a          486 c          664 g         1060 t
ORIGIN      
        1 agctggaaca gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata
       61 tctttcacga gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt
      121 gaaaaataat gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg
      181 tagtgattta actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta
      241 ccatgttact accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa
      301 agtacgatat atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt
      361 ttcttgttaa ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg
      421 aattaattat gaagtgaaat gaatgtaaca gggttcaatt aaaagaggga agcgtatcat
      481 taaccctata aactacgtct gccctcatta ttggagggtg aaatgtgaat acatcctatt
      541 cacaatcgaa tttacgacac aaccaaattt taatttggct ttgcatttta tcttttttta
      601 gcgtattaaa tgaaatggtt ttgaacgtct cattacctga tattgcaaat gattttaata
      661 aaccacctgc gagtacaaac tgggtgaaca cagcctttat gttaaccttt tccattggaa
      721 cagctgtata tggaaagcta tctgatcaat taggcatcaa aaggttactc ctatttggaa
      781 ttataataaa ttgtttcggg tcggtaattg ggtttgttgg ccattctttc ttttccttac
      841 ttattatggc tcgttttatt caaggggctg gtgcagctgc atttccagca ctcgtaatgg
      901 ttgtagttgc gcgctatatt ccaaaggaaa ataggggtaa agcatttggt cttattggat
      961 cgatagtagc catgggagaa ggagtcggtc cagcgattgg tggaatgata gcccattata
     1021 ttcattggtc ctatcttcta ctcattccta tgataacaat tatcactgtt ccgtttctta
     1081 tgaaattatt aaagaaagaa gtaaggataa aaggtcattt tgatatcaaa ggaattatac
     1141 taatgtctgt aggcattgta ttttttatgt tgtttacaac atcatatagc atttcttttc
     1201 ttatcgttag cgtgctgtca ttcctgatat ttgtaaaaca tatcaggaaa gtaacagatc
     1261 cttttgttga tcccggatta gggaaaaata taccttttat gattggagtt ctttgtgggg
     1321 gaattatatt tggaacagta gcagggtttg tctctatggt tccttatatg atgaaagatg
     1381 ttcaccagct aagtactgcc gaaatcggaa gtgtaattat tttccctgga acaatgagtg
     1441 tcattatttt cggctacatt ggtgggatac ttgttgatag aagaggtcct ttatacgtgt
     1501 taaacatcgg agttacattt ctttctgtta gctttttaac tgcttccttt cttttagaaa
     1561 caacatcatg gttcatgaca attataatcg tatttgtttt aggtgggctt tcgttcacca
     1621 aaacagttat atcaacaatt gtttcaagta gcttgaaaca gcaggaagct ggtgctggaa
     1681 tgagtttgct taactttacc agctttttat cagagggaac aggtattgca attgtaggtg
     1741 gtttattatc cataccctta cttgatcaaa ggttgttacc tatggaagtt gatcagtcaa
     1801 cttatctgta tagtaatttg ttattacttt tttcaggaat cattgtcatt agttggctgg
     1861 ttaccttgaa tgtatataaa cattctcaaa gggatttcta aatcgttaag ggatcaactt
     1921 tgggagagag ttcaaaattg atcctttttt tataacagga attcaaatct ttttgttcca
     1981 ttaaagggcg cgattgctga ataaaagata cgagagacct ctcttgtatc ttttttattt
     2041 tgagtggttt tgtccgttac actagaaaac cgaaagacaa taaaaatttt attcttgctg
     2101 agtctggctt tcggtaagct agacaaaacg gacaaaataa aaattggcaa gggtttaaag
     2161 gtggagattt tttgagtgat cttctcaaaa aatactacct gtcccttgct gatttttaaa
     2221 cgagcacgag agcaaaaccc ccctttgctg aggtggcaga gggcaggttt ttttgtttct
     2281 tttttctcgt aaaaaaaaga aaggtcttaa aggttttatg gttttggtcg gcactgccga
     2341 cagcctcgca gagcacacac tttatgaata taaagtatag tgtgttatac tttacttgga
     2401 agtggttgcc ggaaagagcg aaaatgcctc acatttgtgc cacctaaaaa ggagcgattt
     2461 acatatgagt tatgcagttt gtagaatgca aaaagtgaaa tcagctggac taaaaggcat
     2521 gcaatttcat aatcaaagag agcgaaaaag tagaacgaat gatgatattg accatgagcg
     2581 aacacgtgaa aattatgatt tgaaaaatga taaaaatatt gattacaacg aacgtgtcaa
     2641 agaaattatt gaatcacaaa aaacaggtac aagaaaaacg aggaaagatg ctgttcttgt
     2701 aaatgagttg ctagtaacat ctgaccgaga tttttttgag caactggatc caggagaaca
     2761 aaaacgattt tttgaggaaa gttataaatt attttccgaa cgatatggca agcaaaatat
     2821 tgcttatgca acagttcata atgatgagca aacccctcac atgcatttag gtgttgtgcc
     2881 tatgcgtgat ggaaaactgc aaggaaaaaa tgtgtttaat cgtcaagaac tgttatggct
     2941 acaagataaa ttccccgagc atatgaaaaa acagggtttt gagttgaagc gtggtgaacg
     3001 tggctctgac cgtaaacata ttgagacagc taaatttaaa aaacaaactt tggaaaaaga
     3061 gattgatttt ctagaaaaaa atttagcagt taaaaaagat gaatggactg cttatagcga
     3121 taaagttaaa tcagatttag aagtaccagc gaaacgacac atgaaaagtg ttgaagtgcc
     3181 aacgggtgaa aagtccatgt ttggtttggg aaaagggttc tgttgcaaag ttttaaatct
     3241 actatcaaat aag
//
LOCUS       DAKCAA010000217         1504 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.guided.163, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000217 DAKCAA010000000
VERSION     DAKCAA010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.guided.163"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            262..345
                     /locus_tag="OUE31_002912"
                     /pseudo
     CDS             262..345
                     /locus_tag="OUE31_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            394..477
                     /locus_tag="OUE31_002913"
     CDS             394..477
                     /locus_tag="OUE31_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HCU0223825.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            602..1339
                     /gene="erm(B)"
                     /locus_tag="OUE31_002914"
     CDS             602..1339
                     /gene="erm(B)"
                     /locus_tag="OUE31_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCU0223826.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          551 a          224 c          245 g          484 t
ORIGIN      
        1 atttgtatcg ataagaaata gatttaaaaa tttcgctgtt attttgtaca tttaacttga
       61 cggtgacatc tctctattgt gagttattag tggtacagtt ttcaaccgtt ttaattataa
      121 aaaagtggtg catttttaaa ttggcacaaa caggtaacgg ttattgcagg tgtatttctt
      181 atctatgggt ttaacatgga ttttatcatt aaaatcatga gtattgtccg agagtgattg
      241 gtcttgcgta tggttaaccc taaagttatg gaaataagac ttagaagcaa acttaagagt
      301 gtgttgatag tgcattatct taaaattttg tataatagga attgaagtta aattagatgc
      361 taaaaatttg taattaagaa ggagggattc gtcatgttgg tattccaaat gcgttatgta
      421 gataaaacat ctactgtttt gaaacagact aaaaacagtg attacgcaga taaataaata
      481 cgttagatta attcctacca gtgactaatc ttatgacttt ttaaacagat aactaaaatt
      541 acaaacaaat cgtttaactt ctgtatttgt ttatagatgt aatcacttca ggagtgataa
      601 catgaacaaa aatataaaat attctcaaaa ctttttaacg agtgaaaaag tactcaacca
      661 aataataaaa caattgaatt taaaagaaac cgataccgtt tacgaaattg gaacaggtaa
      721 agggcattta acgacgaaac tggctaaaat aagtaaacag gtaacgtcta ttgaattaga
      781 cagtcatcta ttcaacttat cgtcagaaaa attaaaactg aatactcgtg tcactttaat
      841 tcaccaagat attctacagt ttcaattccc taacaaacag aggtataaaa ttgttgggaa
      901 tattccttac catttaagca cacaaattat taaaaaagtg gtttttgaaa gccgtgcgtc
      961 tgacatctat ctgattgttg aagaaggatt ctacaagcgt accttggata ttcaccgaac
     1021 actagggttg ctcttgcaca ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga
     1081 atgctttcat cctaaaccaa aagtaaacag tgtcttaata aaacttaccc gccataccac
     1141 agatgttcca gataaatatt ggaagctata tacgtacttt gtttcaaaat gggtcaatcg
     1201 agaatatcgt caactgttta ctaaaaatca gtttcatcaa gcaatgaaac acgccaaagt
     1261 aaacaattta agtaccgtta cttatgagca agtattgtct atttttaata gttatctatt
     1321 atttaacggg aggaaataat tctatgagtc gcttttgtaa atttggaaag ttacacgtta
     1381 ctaaagggaa tgtagataaa ttattaggta tagggcacct ctaataacta ccaattaatt
     1441 cacctcaaaa tgaaattaga aaaaaacagc gaaattttta aatctatttc ttatcgatac
     1501 aaat
//
LOCUS       DAKCAA010000218         1418 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.guided.168, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000218 DAKCAA010000000
VERSION     DAKCAA010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.guided.168"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            <1..212
                     /locus_tag="OUE31_002915"
     CDS             <1..212
                     /locus_tag="OUE31_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCU0223827.1"
                     /translation="GFYSLFKTLQQNPKYHRTLTTYLNTLLSNSFIINQIVEPQPPEN
                     MMDIPGMADEMRRPMMLIVSAKKKM"
     gene            245..1153
                     /locus_tag="OUE31_002916"
     CDS             245..1153
                     /locus_tag="OUE31_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HCU0223828.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1150..1398
                     /locus_tag="OUE31_002917"
     CDS             1150..1398
                     /locus_tag="OUE31_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin acetyltransferase"
                     /protein_id="HCU0223829.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLLTRGAS"
BASE COUNT          508 a          203 c          309 g          398 t
ORIGIN      
        1 agggatttta ttctttattt aaaactttgc aacagaaccc aaaatatcat agaacactga
       61 ccacatatct aaatacactg ctttcaaata gttttataat aaatcagatt gtggagccac
      121 agccgccaga gaacatgatg gatattccgg ggatggcgga tgaaatgcga cgcccaatga
      181 tgctgattgt atcggcaaaa aagaagatgt aataatatag aaaaaataaa cgaggagtat
      241 gtaaatgaga tcagaaaaag aaatgatgga tttagtactt tctttagcag aacaggatga
      301 acgtattcga attgtgaccc ttgaggggtc acgcgcaaat attaatatac ctaaagatga
      361 atttcaggat tatgatatta catattttgt aagtgatata gaaccgttta tatctaatga
      421 tgactggctt aatcaatttg ggaatataat aatgatgcaa aagccggagg atatggaatt
      481 attcccacct gaagaaaagg gattttccta tcttatgcta tttgatgatt acaataaaat
      541 tgatcttacc ttattgccct tggaagagtt agataattac ctaaagggcg ataaattaat
      601 aaaggttcta attgataaag attgtagaat taaaagggac atagttccga ctgatataga
      661 ttatcatgta agaaagccaa gcgcaaggga gtatgatgat tgctgcaatg aattttggaa
      721 tgtaacacct tatgttatta aaggattgtg ccgtaaggaa attttatttg ctattgatca
      781 ttttaatcag attgttcgcc atgagctgct gagaatgata tcatggaagg tcggcatcga
      841 aacaggcttt aaattaagtg taggcaagaa ctataagttt attgaaaggt atatatccga
      901 ggatttgtgg gagaaacttt tgtccaccta ccggatggat tcctatgaaa acatatggga
      961 agcattattt ctatgccatc aattgttcag ggcggtatcc ggtgaggtgg cggaaaggct
     1021 tcattatgcc tatccggagt atgataggaa tataacaaaa tataccaggg acatgtataa
     1081 aaaatacact ggtaaaaccg gctgcctgga tagcacatat gccgctgata tagaagagag
     1141 gcgggaacag tgattacaga aatgaaagca gggcacctga aagatatcga taaacccagc
     1201 gaaccatttg aggtgatagg taagattata ccgaggtatg aaaacgagaa ttggaccttt
     1261 acagaattac tctatgaagc gccatattta aaaagctacc aagacgaaga ggatgaagag
     1321 gatgaggagg cagattgcct tgaatatatt gacaatactg ataagataat atatctttta
     1381 acccgtggtg ctagttaatt ttaatatcct aaagaata
//
LOCUS       DAKCAA010000219         1349 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.guided.170, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000219 DAKCAA010000000
VERSION     DAKCAA010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.guided.170"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            46..297
                     /locus_tag="OUE31_002918"
                     /pseudo
     CDS             46..297
                     /locus_tag="OUE31_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            390..1184
                     /locus_tag="OUE31_002919"
                     /note="aph(3')-IIIa"
     CDS             390..1184
                     /locus_tag="OUE31_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HCU0223830.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          424 a          234 c          322 g          369 t
ORIGIN      
        1 cattttcctc taggaaaaaa ttaactagca ccacgggtta tcttttatat agaagatatc
       61 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
      121 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
      181 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
      241 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
      301 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
      361 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
      421 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
      481 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
      541 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
      601 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
      661 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
      721 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
      781 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
      841 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
      901 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
      961 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     1021 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     1081 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     1141 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     1201 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     1261 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag gggtcccgag
     1321 cgcctacgag gaatttgtat cgataagaa
//
LOCUS       DAKCAA010000220         1288 bp    DNA     linear   BCT 24-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate
            DTU_2020_1000150_1_SI_ESP_BAR_026
            SAMEA111506025-rid15936023.guided.172, whole genome shotgun
            sequence.
ACCESSION   DAKCAA010000220 DAKCAA010000000
VERSION     DAKCAA010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA111506025
            Sequence Read Archive: ERR10432440
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001493463.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001493463.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/23/2022 00:33:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,920
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,785
            CDSs (with protein)               :: 2,785
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 33 of 71
            Pseudo Genes (incomplete)         :: 34 of 71
            Pseudo Genes (internal stop)      :: 14 of 71
            Pseudo Genes (multiple problems)  :: 10 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA111506025-rid15936023.guided.172"
                     /isolate="DTU_2020_1000150_1_SI_ESP_BAR_026"
                     /isolation_source="biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Spain"
                     /lat_lon="41.40359 N 2.15379 E"
                     /collection_date="2020-02-28"
                     /collected_by="Hospital de Bellvitge"
     gene            574..1122
                     /gene="aac(6')"
                     /locus_tag="OUE31_002920"
     CDS             574..1122
                     /gene="aac(6')"
                     /locus_tag="OUE31_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCU0223831.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          454 a          187 c          257 g          390 t
ORIGIN      
        1 ttaaaattta tatcttgact tattaccatt aggctttctt cgttgaaacg ggttaaaatt
       61 ttaaagagtg atcgatctga ctgcggctgt agatggagta gaggtgaacc taagacagga
      121 taagtgatga ataaggtggc atgaacacct tgaaatcatc aataagtatc ctaaaaacga
      181 acaagtacaa aaacattgaa aacgacaata atgaattttt gttcctctta gtatttctac
      241 cgattccctt tgcttttttg taattatcta aaaattctaa aaattaagat tattatatga
      301 aaacaggttt tatttgtcaa ttcataattg gtttttttta aagcaaaaga taatctatat
      361 catgatgaac aaacagagtt ttttcctcca attgatggct ttcctgatct ttcctatttt
      421 gaataaagtg tttctgtata atttttttat tttataagta agataaataa tgaaagaata
      481 gagatactga ttggtagcta aagatttttg agcgagaaca tttcgttttt tcaaaaggac
      541 tgttagaata agcaagaaca agggggaaga cgtatgataa tcagtgaatt tgaccgtaat
      601 aatccagtat tgaaagatca gctttctgat ttactgagac tgacttggcc ggaagaatat
      661 ggagacagct cggcagaaga agtagaagaa atgatgaatc cagaacgaat cgcggtagca
      721 gcggtagacc aagatgagtt agtaggattt attggtgcaa tccctcaata cggtatcaca
      781 ggttgggaat tgcatccatt agttgtagaa agctcccgac gaaagaacca aataggtact
      841 cgattagtca attacttaga aaaagaagta gcttccagag gaggaatcac gatttattta
      901 ggtacggatg atttagacca tggaacaacg ttaagtcaaa cggacctgta tgagcataca
      961 tttgataaag tggcttccat ccagaacctt cgtgaacatc cgtatgaatt ctatgaaaaa
     1021 ttaggttata aaatcgtagg tgtcttacca aatgcaaatg gctgggacaa accggatatt
     1081 tggatggcaa aaacgattat tcctcgacca aattctcaat aataaaaaga ggttgtgaca
     1141 gaagtaatca gcttcaagaa ataagaagga atttacgaaa attacttctt gaatttttgt
     1201 gaaattccaa cttatttccg aagaagctac ttttggaaca ccgtgtacca gaggttgtga
     1261 aaaagtcgct tagtttcgag tagtaaga
//
